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Center for Computational Systems Medicine
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Fusion Gene Summary

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Fusion Gene ORF analysis

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Fusion Genomic Features

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Fusion Protein Features

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Fusion Gene Sequence

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Fusion Gene PPI analysis

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Related Drugs

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Related Diseases

Fusion gene:PAQR3-ANTXR2 (FusionGDB2 ID:62655)

Fusion Gene Summary for PAQR3-ANTXR2

check button Fusion gene summary
Fusion gene informationFusion gene name: PAQR3-ANTXR2
Fusion gene ID: 62655
HgeneTgene
Gene symbol

PAQR3

ANTXR2

Gene ID

152559

118429

Gene nameprogestin and adipoQ receptor family member 3ANTXR cell adhesion molecule 2
SynonymsRKTGCMG-2|CMG2|HFS|ISH|JHF
Cytomap

4q21.21

4q21.21

Type of geneprotein-codingprotein-coding
Descriptionprogestin and adipoQ receptor family member 3Raf kinase trapping to Golgiprogestin and adipoQ receptor family member IIIanthrax toxin receptor 2capillary morphogenesis gene 2 proteincapillary morphogenesis protein 2
Modification date2020031320200313
UniProtAcc.

P58335

Ensembl transtripts involved in fusion geneENST00000295462, ENST00000380645, 
ENST00000512733, ENST00000515541, 
ENST00000403729, ENST00000295465, 
ENST00000307333, ENST00000346652, 
ENST00000404191, ENST00000482406, 
Fusion gene scores* DoF score3 X 3 X 3=2713 X 11 X 3=429
# samples 313
** MAII scorelog2(3/27*10)=0.15200309344505
effective Gene in Pan-Cancer Fusion Genes (eGinPCFGs).
DoF>8 and MAII>0		log2(13/429*10)=-1.72246602447109
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0
Context

PubMed: PAQR3 [Title/Abstract] AND ANTXR2 [Title/Abstract] AND fusion [Title/Abstract]

Most frequent breakpointPAQR3(79847675)-ANTXR2(80906017), # samples:2
Anticipated loss of major functional domain due to fusion event.
* DoF score (Degree of Frequency) = # partners X # break points X # cancer types
** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10)

check button Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez
PartnerGeneGO IDGO termPubMed ID
HgenePAQR3

GO:0001933

negative regulation of protein phosphorylation

17724343

HgenePAQR3

GO:0010977

negative regulation of neuron projection development

17724343

HgenePAQR3

GO:0033137

negative regulation of peptidyl-serine phosphorylation

17724343

HgenePAQR3

GO:0043407

negative regulation of MAP kinase activity

17724343


check buttonFusion gene breakpoints across PAQR3 (5'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.
all structure

check buttonFusion gene breakpoints across ANTXR2 (3'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.
all structure

check button Fusion gene information from two resources (ChiTars 5.0 and ChimerDB 4.0)
* All genome coordinats were lifted-over on hg19.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
SourceDiseaseSampleHgeneHchrHbpHstrandTgeneTchrTbpTstrand
ChimerDB4PRADTCGA-YJ-A8SW-01APAQR3chr4

79847675

-ANTXR2chr4

80906017

-
ChimerDB4PRADTCGA-YJ-A8SWPAQR3chr4

79847675

-ANTXR2chr4

80906017

-


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Fusion Gene ORF analysis for PAQR3-ANTXR2

check button Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
ORFHenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrand
3UTR-3CDSENST00000295462ENST00000403729PAQR3chr4

79847675

-ANTXR2chr4

80906017

-
3UTR-intronENST00000295462ENST00000295465PAQR3chr4

79847675

-ANTXR2chr4

80906017

-
3UTR-intronENST00000295462ENST00000307333PAQR3chr4

79847675

-ANTXR2chr4

80906017

-
3UTR-intronENST00000295462ENST00000346652PAQR3chr4

79847675

-ANTXR2chr4

80906017

-
3UTR-intronENST00000295462ENST00000404191PAQR3chr4

79847675

-ANTXR2chr4

80906017

-
3UTR-intronENST00000295462ENST00000482406PAQR3chr4

79847675

-ANTXR2chr4

80906017

-
5CDS-intronENST00000380645ENST00000295465PAQR3chr4

79847675

-ANTXR2chr4

80906017

-
5CDS-intronENST00000380645ENST00000307333PAQR3chr4

79847675

-ANTXR2chr4

80906017

-
5CDS-intronENST00000380645ENST00000346652PAQR3chr4

79847675

-ANTXR2chr4

80906017

-
5CDS-intronENST00000380645ENST00000404191PAQR3chr4

79847675

-ANTXR2chr4

80906017

-
5CDS-intronENST00000380645ENST00000482406PAQR3chr4

79847675

-ANTXR2chr4

80906017

-
5CDS-intronENST00000512733ENST00000295465PAQR3chr4

79847675

-ANTXR2chr4

80906017

-
5CDS-intronENST00000512733ENST00000307333PAQR3chr4

79847675

-ANTXR2chr4

80906017

-
5CDS-intronENST00000512733ENST00000346652PAQR3chr4

79847675

-ANTXR2chr4

80906017

-
5CDS-intronENST00000512733ENST00000404191PAQR3chr4

79847675

-ANTXR2chr4

80906017

-
5CDS-intronENST00000512733ENST00000482406PAQR3chr4

79847675

-ANTXR2chr4

80906017

-
5UTR-3CDSENST00000515541ENST00000403729PAQR3chr4

79847675

-ANTXR2chr4

80906017

-
5UTR-intronENST00000515541ENST00000295465PAQR3chr4

79847675

-ANTXR2chr4

80906017

-
5UTR-intronENST00000515541ENST00000307333PAQR3chr4

79847675

-ANTXR2chr4

80906017

-
5UTR-intronENST00000515541ENST00000346652PAQR3chr4

79847675

-ANTXR2chr4

80906017

-
5UTR-intronENST00000515541ENST00000404191PAQR3chr4

79847675

-ANTXR2chr4

80906017

-
5UTR-intronENST00000515541ENST00000482406PAQR3chr4

79847675

-ANTXR2chr4

80906017

-
In-frameENST00000380645ENST00000403729PAQR3chr4

79847675

-ANTXR2chr4

80906017

-
In-frameENST00000512733ENST00000403729PAQR3chr4

79847675

-ANTXR2chr4

80906017

-

check buttonORFfinder result based on the fusion transcript sequence of in-frame fusion genes.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandSeq length
(transcript)		BP loci
(transcript)		Predicted start
(transcript)		Predicted stop
(transcript)		Seq length
(amino acids)
ENST00000512733PAQR3chr479847675-ENST00000403729ANTXR2chr480906017-7622916731341422
ENST00000380645PAQR3chr479847675-ENST00000403729ANTXR2chr480906017-7587881381306422

check buttonDeepORF prediction of the coding potential based on the fusion transcript sequence of in-frame fusion genes. DeepORF is a coding potential classifier based on convolutional neural network by comparing the real Ribo-seq data. If the no-coding score < 0.5 and coding score > 0.5, then the in-frame fusion transcript is predicted as being likely translated.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandNo-coding scoreCoding score
ENST00000512733ENST00000403729PAQR3chr479847675-ANTXR2chr480906017-0.0005758010.9994242
ENST00000380645ENST00000403729PAQR3chr479847675-ANTXR2chr480906017-0.0005671990.99943274

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Fusion Genomic Features for PAQR3-ANTXR2


check buttonFusionAI prediction of the potential fusion gene breakpoint based on the pre-mature RNA sequence context (+/- 5kb of individual partner genes, total 20kb length sequence). FusionAI is a fusion gene breakpoint classifier based on convolutional neural network by comparing the fusion positive and negative sequence context of ~ 20K fusion gene data. From here, we can have the relative potentency of the 20K genomic sequence how individual sequnce will be likely used as the gene fusion breakpoints.
HgeneHchrHbpHstrandTgeneTchrTbpTstrand1-pp (fusion gene breakpoint)

check buttonDistribution of 44 human genomic features loci across 20kb length fusion breakpoint regions. We integrated a total of 44 different types of human genomic feature loci information across five big categories including virus integration sites, repeats, structural variants, chromatin states, and gene expression regulation. More details are in help page.
genomic feature

check buttonDistribution of 44 human genomic features loci across 20kb length fusion breakpoint regions that are ovelapped with the top 1% feature importance score regions. More details are in help page.

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Fusion Protein Features for PAQR3-ANTXR2


check button Four levels of functional features of fusion genes
Go to FGviewer search page for the most frequent breakpoint (https://ccsmweb.uth.edu/FGviewer/chr4:79847675/chr4:80906017)
- FGviewer provides the online visualization of the retention search of the protein functional features across DNA, RNA, protein, and pathological levels.
- How to search
1. Put your fusion gene symbol.
2. Press the tab key until there will be shown the breakpoint information filled.
4. Go down and press 'Search' tab twice.
4. Go down to have the hyperlink of the search result.
5. Click the hyperlink.
6. See the FGviewer result for your fusion gene.
FGviewer

check buttonMain function of each fusion partner protein. (from UniProt)
HgeneTgene
.ANTXR2

P58335

FUNCTION: Transcriptional activator which is required for calcium-dependent dendritic growth and branching in cortical neurons. Recruits CREB-binding protein (CREBBP) to nuclear bodies. Component of the CREST-BRG1 complex, a multiprotein complex that regulates promoter activation by orchestrating a calcium-dependent release of a repressor complex and a recruitment of an activator complex. In resting neurons, transcription of the c-FOS promoter is inhibited by BRG1-dependent recruitment of a phospho-RB1-HDAC1 repressor complex. Upon calcium influx, RB1 is dephosphorylated by calcineurin, which leads to release of the repressor complex. At the same time, there is increased recruitment of CREBBP to the promoter by a CREST-dependent mechanism, which leads to transcriptional activation. The CREST-BRG1 complex also binds to the NR2B promoter, and activity-dependent induction of NR2B expression involves a release of HDAC1 and recruitment of CREBBP (By similarity). {ECO:0000250}.FUNCTION: Necessary for cellular interactions with laminin and the extracellular matrix. {ECO:0000269|PubMed:11683410, ECO:0000269|PubMed:12973667}.

check buttonRetention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at

download page


* Minus value of BPloci means that the break pointn is located before the CDS.
- In-frame and retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
HgenePAQR3chr4:79847675chr4:80906017ENST00000295462-312299_30317923.0RegionNote=Golgi targeting
HgenePAQR3chr4:79847675chr4:80906017ENST00000295462-31261_7117923.0RegionNote=Golgi targeting
HgenePAQR3chr4:79847675chr4:80906017ENST00000512733-4661_71234312.0RegionNote=Golgi targeting
HgenePAQR3chr4:79847675chr4:80906017ENST00000295462-312129_14017923.0Topological domainCytoplasmic
HgenePAQR3chr4:79847675chr4:80906017ENST00000295462-312164_17217923.0Topological domainLumenal
HgenePAQR3chr4:79847675chr4:80906017ENST00000295462-312196_20117923.0Topological domainCytoplasmic
HgenePAQR3chr4:79847675chr4:80906017ENST00000295462-3121_7317923.0Topological domainCytoplasmic
HgenePAQR3chr4:79847675chr4:80906017ENST00000295462-312225_23817923.0Topological domainLumenal
HgenePAQR3chr4:79847675chr4:80906017ENST00000295462-312257_27517923.0Topological domainCytoplasmic
HgenePAQR3chr4:79847675chr4:80906017ENST00000295462-312299_31117923.0Topological domainLumenal
HgenePAQR3chr4:79847675chr4:80906017ENST00000295462-31297_10517923.0Topological domainLumenal
HgenePAQR3chr4:79847675chr4:80906017ENST00000512733-46129_140234312.0Topological domainCytoplasmic
HgenePAQR3chr4:79847675chr4:80906017ENST00000512733-46164_172234312.0Topological domainLumenal
HgenePAQR3chr4:79847675chr4:80906017ENST00000512733-46196_201234312.0Topological domainCytoplasmic
HgenePAQR3chr4:79847675chr4:80906017ENST00000512733-461_73234312.0Topological domainCytoplasmic
HgenePAQR3chr4:79847675chr4:80906017ENST00000512733-4697_105234312.0Topological domainLumenal
HgenePAQR3chr4:79847675chr4:80906017ENST00000295462-312106_12817923.0TransmembraneHelical
HgenePAQR3chr4:79847675chr4:80906017ENST00000295462-312141_16317923.0TransmembraneHelical
HgenePAQR3chr4:79847675chr4:80906017ENST00000295462-312173_19517923.0TransmembraneHelical
HgenePAQR3chr4:79847675chr4:80906017ENST00000295462-312202_22417923.0TransmembraneHelical
HgenePAQR3chr4:79847675chr4:80906017ENST00000295462-312239_25617923.0TransmembraneHelical
HgenePAQR3chr4:79847675chr4:80906017ENST00000295462-312276_29817923.0TransmembraneHelical
HgenePAQR3chr4:79847675chr4:80906017ENST00000295462-31274_9617923.0TransmembraneHelical
HgenePAQR3chr4:79847675chr4:80906017ENST00000512733-46106_128234312.0TransmembraneHelical
HgenePAQR3chr4:79847675chr4:80906017ENST00000512733-46141_163234312.0TransmembraneHelical
HgenePAQR3chr4:79847675chr4:80906017ENST00000512733-46173_195234312.0TransmembraneHelical
HgenePAQR3chr4:79847675chr4:80906017ENST00000512733-46202_224234312.0TransmembraneHelical
HgenePAQR3chr4:79847675chr4:80906017ENST00000512733-4674_96234312.0TransmembraneHelical
TgeneANTXR2chr4:79847675chr4:80906017ENST00000295465011352_3600323.0Compositional biasNote=Poly-Pro
TgeneANTXR2chr4:79847675chr4:80906017ENST00000295465011362_3660323.0Compositional biasNote=Poly-Glu
TgeneANTXR2chr4:79847675chr4:80906017ENST000003073331116352_360347490.0Compositional biasNote=Poly-Pro
TgeneANTXR2chr4:79847675chr4:80906017ENST000003073331116362_366347490.0Compositional biasNote=Poly-Glu
TgeneANTXR2chr4:79847675chr4:80906017ENST00000346652712352_360244387.0Compositional biasNote=Poly-Pro
TgeneANTXR2chr4:79847675chr4:80906017ENST00000346652712362_366244387.0Compositional biasNote=Poly-Glu
TgeneANTXR2chr4:79847675chr4:80906017ENST000004037291117352_360347489.0Compositional biasNote=Poly-Pro
TgeneANTXR2chr4:79847675chr4:80906017ENST000004037291117362_366347489.0Compositional biasNote=Poly-Glu
TgeneANTXR2chr4:79847675chr4:80906017ENST0000029546501144_2130323.0DomainVWFA
TgeneANTXR2chr4:79847675chr4:80906017ENST00000295465011342_4890323.0Topological domainCytoplasmic
TgeneANTXR2chr4:79847675chr4:80906017ENST0000029546501134_3180323.0Topological domainExtracellular
TgeneANTXR2chr4:79847675chr4:80906017ENST00000346652712342_489244387.0Topological domainCytoplasmic
TgeneANTXR2chr4:79847675chr4:80906017ENST00000295465011319_3410323.0TransmembraneHelical
TgeneANTXR2chr4:79847675chr4:80906017ENST00000346652712319_341244387.0TransmembraneHelical

- In-frame and not-retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
HgenePAQR3chr4:79847675chr4:80906017ENST00000512733-46299_303234312.0RegionNote=Golgi targeting
HgenePAQR3chr4:79847675chr4:80906017ENST00000512733-46225_238234312.0Topological domainLumenal
HgenePAQR3chr4:79847675chr4:80906017ENST00000512733-46257_275234312.0Topological domainCytoplasmic
HgenePAQR3chr4:79847675chr4:80906017ENST00000512733-46299_311234312.0Topological domainLumenal
HgenePAQR3chr4:79847675chr4:80906017ENST00000512733-46239_256234312.0TransmembraneHelical
HgenePAQR3chr4:79847675chr4:80906017ENST00000512733-46276_298234312.0TransmembraneHelical
TgeneANTXR2chr4:79847675chr4:80906017ENST00000307333111644_213347490.0DomainVWFA
TgeneANTXR2chr4:79847675chr4:80906017ENST0000034665271244_213244387.0DomainVWFA
TgeneANTXR2chr4:79847675chr4:80906017ENST00000403729111744_213347489.0DomainVWFA
TgeneANTXR2chr4:79847675chr4:80906017ENST000003073331116342_489347490.0Topological domainCytoplasmic
TgeneANTXR2chr4:79847675chr4:80906017ENST00000307333111634_318347490.0Topological domainExtracellular
TgeneANTXR2chr4:79847675chr4:80906017ENST0000034665271234_318244387.0Topological domainExtracellular
TgeneANTXR2chr4:79847675chr4:80906017ENST000004037291117342_489347489.0Topological domainCytoplasmic
TgeneANTXR2chr4:79847675chr4:80906017ENST00000403729111734_318347489.0Topological domainExtracellular
TgeneANTXR2chr4:79847675chr4:80906017ENST000003073331116319_341347490.0TransmembraneHelical
TgeneANTXR2chr4:79847675chr4:80906017ENST000004037291117319_341347489.0TransmembraneHelical


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Fusion Gene Sequence for PAQR3-ANTXR2


check button For in-frame fusion transcripts, we provide the fusion transcript sequences and fusion amino acid sequences. To have fusion amino acid sequence, we ran ORFfinder and chose the longest ORF among the all predicted ones.
>62655_62655_1_PAQR3-ANTXR2_PAQR3_chr4_79847675_ENST00000380645_ANTXR2_chr4_80906017_ENST00000403729_length(transcript)=7587nt_BP=881nt
GCTGGCGGCAGTGGCCGGTGTGAGCGCAGAGCCGGGCCCTGGGCAGCAGCGGCAGCGCGGTAGGACCTCGCGCAGCGTCCGCGGGCTCCG
GGGCGGGGGCGCCAGCGGCGAAGCCCCCTCCCCGGGGAGGCGGGACCTGGGGGAGCTCCCGAGCCGGGGAGCGGCGGCGGCCGGGAACGA
TGCATCAGAAGCTGCTGAAGAGCGCGCATTACATCGAGCTGGGCAGCTACCAGTACTGGCCGGTCCTGGTGCCCCGTGGCATCCGCCTGT
ACACCTACGAGCAGATCCCCGGGTCCCTCAAGGACAACCCGTACATCACCGACGGCTACCGGGCCTACCTGCCGTCCAGGCTGTGTATCA
AAAGTTTGTTTATTTTATCTAATGAGACAGTAAACATCTGGAGTCATTTGCTGGGTTTCTTTCTCTTCTTCACCCTGGGAATATATGACA
TGACATCTGTGTTACCTTCAGCAAGTGCGTCCAGAGAAGATTTTGTAATTTGTTCTATTTGTCTTTTCTGCTTCCAGGTCTGTATGCTTT
GCTCTGTGGGCTATCATCTTTTTTCCTGCCATCGGTCAGAAAAAACATGTCGAAGATGGATGGCATTAGATTATGCAGGAATTTCTATTG
GAATACTGGGCTGCTATGTCTCAGGAGTATTTTACGCATTTTATTGTAATAACTACTGGCGTCAGGTGTACTTGATCACAGTGCTTGCTA
TGATCCTGGCAGTGTTCTTTGCGCAGATTCATCCCAATTACCTCACGCAGCAATGGCAAAGGCTCCGTTCTATCATCTTTTGTTCTGTTT
CGGGATATGGAGTGATTCCTACTCTTCACTGGGTTTGGCTCAATGGAGGAATTGGTGCTCCTATTGTACAGGTTATTAAGGATCCTCCAC
CACCACCCGCCCCTGCACCAAAAGAGGAGGAAGAAGAACCTTTGCCTACTAAAAAGTGGCCAACTGTGGATGCTTCCTATTATGGTGGTC
GAGGGGTTGGAGGAATTAAAAGAATGGAGGTTCGTTGGGGTGATAAAGGATCTACTGAGGAAGGTGCAAGGCTAGAGAAAGCCAAAAATG
CTGTGGTGAAGATTCCTGAAGAAACAGAGGAACCCATCAGGCCTAGACCACCTCGACCCAAACCCACACACCAGCCTCCTCAGACAAAAT
GGTACACCCCAATTAAGGGTCGTCTTGATGCTCTCTGGGCTTTGTTGAGGCGGCAGTATGACCGGGTTTCTTTGATGCGACCTCAGGAAG
GAGATGAGGGCCGGTGCATAAACTTCTCCCGAGTTCCATCTCAGTAAAAGGGAAGCAGGAAGACCAAGAAGGTACGAAGATGGCACATTT
TCACATAGCTGATTTTCAACCAAATGAAAAAAATCAAGTGCATTTCAGAAGCTTTTGGAAGAGCAGCTTAATTCCTCTCAGTCGGGAAAT
GTTTTCTCTGCCTTCTGCTTTGCTTGCACCAAACATTTCTAAACACTTGTTCTGCCATCTACATGGGAGGTGATGAAACTCAGTGGTAAC
TCATGATTTATGACATTGAAAATAAAGAGGAACATTGACCTGCAGACTATGGTTTGTACAAGAAAGTTTGTTTGAATGTGTAGAAGAGGA
AAAAGCAACAACAGCAACAACACGAAGATGATACCAAAACAAGGACCACAAAACAACTAGCCATGATGGGAGACAGGAGTTTTTTACATG
GAAACATGGCACTTGTGTTTTTATGTGGCAAGATCTTTATCCATAGGCAGAGTATGAAATTTCCCACCAGGCTAAGCAAATAAAGAAGTC
CATTGCCTTATAGCTATGTCAGATCACAGAATCCTTCCAAGTGCTCTATCACAGTGTGCCTTATGGGAAGTTTCTGACTGGAAAATCTTG
TCATTCTAACACTGAAAAGTGCACACGCATGACAAAATGTAGACAAGATGCCTCAAGGTATTGGTAGCAAGCAAGATTTTGCCCTTTAGT
TTTCGAAGACACCTTTCTTTCATTATGCACTCGGGACAAGAAAATTAATAGAGCGTTATTCCACAGAAGGCCTCTAGCCAGAGATCTTGA
GTGTAGTGCAAGGGACTCATTTTTTGCGAACTTGTCCCTGTGACTAGTAGATTCCCCCTTTTCCTGTGTTTAGGATTTAGTAGTGCATAA
AGCATTAATATCCATAAACATACCTAGAAGTTTGTTTTGCTTTTAATTTAAAGGAAGCAGTAACCACAAAGCTTCCGCTCAGGGTTTTTT
CTTTCTTCAAGTCTCCAAGGGCTCTTCAGCGTCACAAGCCAGCAACTCTCTTTGCATTAAAATTTCAAAGTTTAATTAATATAATTAAAA
GCAACAGCAAGCAGCAGCCTGTGAAGATTTTGCTCATCTTTTTTATGCCTTTTGACATTGAATGACCTATTACTGTATGCGCATTACTTG
GATTTTGAGGGGCACTCTACCTTGGTTATGATTCAGTAGAGGAAAAAGACCACCTTTCTTCAATTTACAAATTAAATCTTCTGGAGGGTC
GCTATCACAAAACATTGACGATGTATGTATTATAATTTTTTAGAAAAACCACCATCGTGTCACGTCGACGATGCCAAATTATGTTAGCGT
GAGCAGAAACACCGTGGGGGAGGAAGGCAGCAGCTGAAGAAAAAAGCTCAAATGATCTAGTCACTTTCGATACTGTACTTCAGATGCGAA
ATGGATATTCGAGTGGAAACCTGACAAAGTGCGCCTGCTTTGATGTGAACTGGTATAGACAATGACCAGTGGCTGGGTCAGTGGGATGTC
TCTCTGTGAGCACAAAGGCTTATCAAATGACACTAAAAATAAGTTCAACAACCATCACATTGGAAGGGAGAAGGCGAACATTTCATGTTT
GGCGGGCATGTGAGTGCACAAGATGGAAAGAGCGATTGGAGCATCCTGGTATAATTACCCCCATTGTGCTCTTAATGGAAATTTCAAAGG
ACGGGAGTATTCTGTTGGTTGGTGTCCAGGTTTGTGGCACTGTTCCAAGAGGCCTTACACACACACACAAATATATAATTTTCTATACAT
ATATATCCTCTAGCTTGAAACTTTTGCTCAAGTTTATTTATGTCACTGGCTGGCTGGATCCAAAGTCATGTGTCCACACATTCATAAATA
AAAATTTTACCTATGCCTGTGCTACCATTTCTTTAAGCCCACATAAAGCTAATGCCTTCTTGGGTTGAATATGCAGTTGTTATGCTTAGT
TTCAGGGATGGAATTCTATTCAGTTCCAAAATGTCCCTCATGTTCACAGATGATACTATTGGCAGTAGCTGCATATGCAAGTGTAACTTG
GAAGCCTGATATAGTATACCCAACCCTTTCTGCAATGAGTTATTGTATCCCTTTGTTCTGCATTTGCATCTGGAACAAGACCTAATGTGG
CTTCCTTAAATGGGCACTTCATTTCTGATGAGTGCACACCAATTATTGCTATTTTAATATCATTGAGAATACTACAGAAGCTAAGGCTAT
GTTTCTTTGGTAACTACTTCAAATTTCTCTAGAATTATGTAGCATACTTACATTTTGCTGCATGAACAATGAAAATTAACCTCTGCCTTT
AAATGGAAAAATAACTTTCTGTAGATTGTTATACAGCTACTATGAAGAGCTCTTAATGAAGAGGAAGTGGCAGTGGTCTATATGTAGACT
GAAAAAATATCATTAATAAAGTTCAAAGACTGATGGAATTTCATTGCCCTTAAAGATATGAACCAGATCTGTTTTATGCTTTTCTCCAAT
TATACTAACTAGCAGTTGAAAAGAATTTGTTTTGAAGAGTGTTATTTTCTTACCAAAAGACCAGATCAAAAATCCCTATACTTTTCCACC
AAAAAAAGATTAAAATGAAGCCATTTCTATAAATTTAATGGCACTTTATATTTTATATAGAGAAATAGCTTCTGTTTGATTTTCTGGACA
CCATGTCAGTCAAGATCTACTTTCTGTGTAAAAATGAATAAGTCTTGCACATAATCCATTCGTGTTGCATAAGGTTGCAAAAACAATTAA
GTGGGAAATGACTCCTAACTTATGTGTCTACTCTGCCTAGAAAGAAAGTTTTGAAGGCATCTATATATATTTCATAACAATGTCTGTTCT
TTATGGATTTGATCCATAAATATTTATCTATCTGAAAACTTTGATACTTGGAATGTTTTCCTTAGAGCATTTGGTGCTCCAAGAAAAAAC
ATTTGGTGCTAAGAGTTGCAGCACTGATGCCTTTCCCTAAGTTAATTCTATTTTAAAAATTTATATTTCCTTCCCAATGAGATGCAGAGT
AAAATTTGAGACCCTCCATTGACTAGGGAGCAGCATCTGTCATCTATGGTTAATTACTATTTTGACAAAAATATAGAAGGTTTAAACCCC
CATGTATTTCAGATTGTTAGAGAAAGAAGTAGTTTGCTTATATTTCCCTTGAACTTTATTCTAACCATTTAAATAATAAATTATTCAATA
TTTGTTATAATAAATCCTTACTAGATACAAGATTTGGGTGTTTCTGTGAAGTTAACTTTATTATCTAAATATCACTAACCATTGTTTACT
GCTCAGAGGCAGATACATTTGTTTAGTTTAAAGTTGAAACAAATTCTATATTGTGGATAATTAGGTGTTTAAAACATTTTGATAGACCAG
CTTATATATGTTATTTTTGAAATTTAAGAAGGCAGAATGTAATTAGGTCACATTTACAAGTAGAAGGAATTATAACTTCCTACTCCATGC
ATATATTGTATATTGGTTAGCTTTTACTAGCATTTTCTAGCATCACATTACTTTAGAAAGTTTTTGAGAGTTTCATTACTACTGGAAAAG
TTTGGTGGGTATATGTACACAGGAAAGAAATATATGCATCATTTCAATATGAAAGGAAATACATAATCTAGAAACATAGAATAACTCTTG
GTACATCTGTTACATAGTTAAGGAAAGAAACAGGCAGGTGAGGCTGGAGAATGTTGTCTATTTGTAGGAAATAAAGTCAGTGCAGACGCA
TATTCTAGTTTAGAGTTAGATTAATATTGTGCTTAGTGAATTTCTATGACATATTTCTGAGAACACTTTAATATATTTCCACACCTACTG
GAATCTAATTCAGTCGATCGGATAAAAGAAAGACTTTTTTGTTGTTGTTTTTGAAAATCCATAATGTAGCAGGTTCTGCGCTGGTTTTTT
AATGTATTTTATTTTTGTGCTCTCCTGCCAAAAGAAAAGGCTGATAAGTAAGTACACAGTACAACATGTAAATTTGTATAAAAATATGCT
TGTTTAGATTGCTCTACAATAACTATATTAAGGTAAATTGTGTGTGTGTGTGTGAGAGAGAGAGAGAGAGAGAGAAACAGAGGGAGAATT
GACTCAATGTGTTTTCTATGAAGAGTCTTAGCTTAGGAATCAGGTAACAGAGAGGTCCTAGACCATAGACCCAGCCATCAACTAGCTTGC
TGATGTTGAACAGATCAACTCTCAACCATAGACTGAAGATGGAATGAAGATATCAAAAGTTCCTTTTAGCACTGACTAGATTTTTTTTCT
TTTTTTTGAAACAGAGTCTCACTCTGTCACCCAGGCTGGAGTTCAATGGCATGGTCTGGGCTGACTGTAACCTCCTCTTCCTGGGTTCAA
GTGATTCTCATCCCTCAGCCTCCTGAGTAGCTGGGATTACAGGCACATAACACCACACCCAGCTAACTCTTGTATTTTTGTAGAAATGGG
GTTTCGCTATGTTGCTCAGACTGGTCTCAAACACCTGGCCTCAAGTGATCCTCCTGCCTCAGTCTCCCAAATGCTGTGATTACAGGCACA
AGCTACTGCACCAGGCCTCTGACTACATTTCTATTAATATGGTTAGGTTGGAGGTTTTAGTATTTTTGTATCTCATATTTGTATCAATAT
GACTGGCTTCTTTGTCTGTAGTGTGTGGTAATATTAGTTCTGTAAACTGTCAGTTGCAAAAAAAAAAAATACCTTGAACTATAGTATATG
TTGATAATTAGCCATAATAATTTCTTAGTTAATTTCTTATAATTAAATTTGTCAAAGAGGAAACTTACAGTTTATATCTGATGAAATCTC
TAAAAAGATGGGTAAAACATTGGGAAATGTATGCATGTACTTCACTCTGGTTTCATAGGGTTAGCAAGTGTCTTAAAAACATATATAAAG
AAGCACAGAGATTGTTAGGAGATATTTATGCTCCCAGTTTTAATAATTGGGATACTTTGTATACCACAGAAAGAAAAATTACTAAACTCC
TCTTTTTTTAGTCAAAATTGGAAAAAAAGTCTTAATTGACAGTTACTATGCCTGTGCTACCCATAGCAAGTATTCAGTGGAAAATACTTT
ACTAAGTAAGTAATTTGAACACAGCTTAAAATCCATAGTATGTTACAATTGCTAGCCTTTCACAAAGTTTGCATTGTCTTAATGTAGAAG
GATACTGTGATCTAAGAATTCACAATTTTAAAAAGTGGAACCTAAATAGGGTTTCCTAATTGCCATGAAGTTATTTGTATCTTAGATGAA
TTATATTTACAACATTGTAAATGTCAGTGGGTGATCCAAAATAAATTGTTAAAGTTATTAAAATGTACATTTAAGTAGGTTTCAGTTTGA
CTAGAAATAATTGGCAAGAAGGCAAGAACTAGTCTTCTAGAGCAGGGATCCCATCCCCCAGGTCATGGACTGGTACTGGTCCATGGCCTG
TTAGAAACCAGGCCACACAGCAGGAGATGAGTGGAAAGCAAGTGAAACTTCATGGGTATTTACAGCAATTCCCCGTCGCTCGCATTACCA
CCTGAGCTGTGTCTCCTGTGAGATCAGCAGCAGCATTAGATTCTCAAGGAGCACAAACCCTTTTGGAACTGTGTGTGAGGGATCTAAGTT
GCGCATTTCTTATGAGAATCTAATACCTGATGATCTGTTGTTGTCTCCCACCACCCCCAGATGGGACCATCTAGTTGCAGGAAAACAAGC
TCAGGCTCCCACTGATTCTACATTATAGTGAGTTGTGTAATTATTTCATTATATATAACAATGTAATAATAATAGAAATAAAGTACATAA
TAAATGTAATCCACTTGAATTATCCTGAAACCATCCCCACCCCCCACCCCCCGGTCTGTGGAAAAATTGGCTTCCACGAAACTGGTCCGT
GGTGCCAAAAATATTGGGTATGGTTGTTCTAGGGTGTAGACTATGAAAAAGATATGCATTGTCTCCATGAACTAAAAGGCAAGGTGATTT
TAAACAATTTAGATGCCAAACAAAGAAACCAAAAGCTTCCAAAGTAATAAATGATAGAGAAAGGAAATTGTTACATCATGTGCCAAATTA
GAAGCAAATCTAAACTTCTTATCATGTACTCCACCATCTGATTTGTATAAGTAATTGGGGAAAGAAAAACTCACAATATAAAACAAGATT
GACTAGTTCTAGCAGATGACACCTGTAAATAGAATTTTTACTAGTTGAAATTCTGATGTGAAATGAAGCCATTATTATTATCACAATAAA

>62655_62655_1_PAQR3-ANTXR2_PAQR3_chr4_79847675_ENST00000380645_ANTXR2_chr4_80906017_ENST00000403729_length(amino acids)=422AA_BP=280
MGSSGSAVGPRAASAGSGAGAPAAKPPPRGGGTWGSSRAGERRRPGTMHQKLLKSAHYIELGSYQYWPVLVPRGIRLYTYEQIPGSLKDN
PYITDGYRAYLPSRLCIKSLFILSNETVNIWSHLLGFFLFFTLGIYDMTSVLPSASASREDFVICSICLFCFQVCMLCSVGYHLFSCHRS
EKTCRRWMALDYAGISIGILGCYVSGVFYAFYCNNYWRQVYLITVLAMILAVFFAQIHPNYLTQQWQRLRSIIFCSVSGYGVIPTLHWVW
LNGGIGAPIVQVIKDPPPPPAPAPKEEEEEPLPTKKWPTVDASYYGGRGVGGIKRMEVRWGDKGSTEEGARLEKAKNAVVKIPEETEEPI

--------------------------------------------------------------
>62655_62655_2_PAQR3-ANTXR2_PAQR3_chr4_79847675_ENST00000512733_ANTXR2_chr4_80906017_ENST00000403729_length(transcript)=7622nt_BP=916nt
AGAGGAGGCTGCGACGCTGCCGGGTCCGCCGCGGCGCTGGCGGCAGTGGCCGGTGTGAGCGCAGAGCCGGGCCCTGGGCAGCAGCGGCAG
CGCGGTAGGACCTCGCGCAGCGTCCGCGGGCTCCGGGGCGGGGGCGCCAGCGGCGAAGCCCCCTCCCCGGGGAGGCGGGACCTGGGGGAG
CTCCCGAGCCGGGGAGCGGCGGCGGCCGGGAACGATGCATCAGAAGCTGCTGAAGAGCGCGCATTACATCGAGCTGGGCAGCTACCAGTA
CTGGCCGGTCCTGGTGCCCCGTGGCATCCGCCTGTACACCTACGAGCAGATCCCCGGGTCCCTCAAGGACAACCCGTACATCACCGACGG
CTACCGGGCCTACCTGCCGTCCAGGCTGTGTATCAAAAGTTTGTTTATTTTATCTAATGAGACAGTAAACATCTGGAGTCATTTGCTGGG
TTTCTTTCTCTTCTTCACCCTGGGAATATATGACATGACATCTGTGTTACCTTCAGCAAGTGCGTCCAGAGAAGATTTTGTAATTTGTTC
TATTTGTCTTTTCTGCTTCCAGGTCTGTATGCTTTGCTCTGTGGGCTATCATCTTTTTTCCTGCCATCGGTCAGAAAAAACATGTCGAAG
ATGGATGGCATTAGATTATGCAGGAATTTCTATTGGAATACTGGGCTGCTATGTCTCAGGAGTATTTTACGCATTTTATTGTAATAACTA
CTGGCGTCAGGTGTACTTGATCACAGTGCTTGCTATGATCCTGGCAGTGTTCTTTGCGCAGATTCATCCCAATTACCTCACGCAGCAATG
GCAAAGGCTCCGTTCTATCATCTTTTGTTCTGTTTCGGGATATGGAGTGATTCCTACTCTTCACTGGGTTTGGCTCAATGGAGGAATTGG
TGCTCCTATTGTACAGGTTATTAAGGATCCTCCACCACCACCCGCCCCTGCACCAAAAGAGGAGGAAGAAGAACCTTTGCCTACTAAAAA
GTGGCCAACTGTGGATGCTTCCTATTATGGTGGTCGAGGGGTTGGAGGAATTAAAAGAATGGAGGTTCGTTGGGGTGATAAAGGATCTAC
TGAGGAAGGTGCAAGGCTAGAGAAAGCCAAAAATGCTGTGGTGAAGATTCCTGAAGAAACAGAGGAACCCATCAGGCCTAGACCACCTCG
ACCCAAACCCACACACCAGCCTCCTCAGACAAAATGGTACACCCCAATTAAGGGTCGTCTTGATGCTCTCTGGGCTTTGTTGAGGCGGCA
GTATGACCGGGTTTCTTTGATGCGACCTCAGGAAGGAGATGAGGGCCGGTGCATAAACTTCTCCCGAGTTCCATCTCAGTAAAAGGGAAG
CAGGAAGACCAAGAAGGTACGAAGATGGCACATTTTCACATAGCTGATTTTCAACCAAATGAAAAAAATCAAGTGCATTTCAGAAGCTTT
TGGAAGAGCAGCTTAATTCCTCTCAGTCGGGAAATGTTTTCTCTGCCTTCTGCTTTGCTTGCACCAAACATTTCTAAACACTTGTTCTGC
CATCTACATGGGAGGTGATGAAACTCAGTGGTAACTCATGATTTATGACATTGAAAATAAAGAGGAACATTGACCTGCAGACTATGGTTT
GTACAAGAAAGTTTGTTTGAATGTGTAGAAGAGGAAAAAGCAACAACAGCAACAACACGAAGATGATACCAAAACAAGGACCACAAAACA
ACTAGCCATGATGGGAGACAGGAGTTTTTTACATGGAAACATGGCACTTGTGTTTTTATGTGGCAAGATCTTTATCCATAGGCAGAGTAT
GAAATTTCCCACCAGGCTAAGCAAATAAAGAAGTCCATTGCCTTATAGCTATGTCAGATCACAGAATCCTTCCAAGTGCTCTATCACAGT
GTGCCTTATGGGAAGTTTCTGACTGGAAAATCTTGTCATTCTAACACTGAAAAGTGCACACGCATGACAAAATGTAGACAAGATGCCTCA
AGGTATTGGTAGCAAGCAAGATTTTGCCCTTTAGTTTTCGAAGACACCTTTCTTTCATTATGCACTCGGGACAAGAAAATTAATAGAGCG
TTATTCCACAGAAGGCCTCTAGCCAGAGATCTTGAGTGTAGTGCAAGGGACTCATTTTTTGCGAACTTGTCCCTGTGACTAGTAGATTCC
CCCTTTTCCTGTGTTTAGGATTTAGTAGTGCATAAAGCATTAATATCCATAAACATACCTAGAAGTTTGTTTTGCTTTTAATTTAAAGGA
AGCAGTAACCACAAAGCTTCCGCTCAGGGTTTTTTCTTTCTTCAAGTCTCCAAGGGCTCTTCAGCGTCACAAGCCAGCAACTCTCTTTGC
ATTAAAATTTCAAAGTTTAATTAATATAATTAAAAGCAACAGCAAGCAGCAGCCTGTGAAGATTTTGCTCATCTTTTTTATGCCTTTTGA
CATTGAATGACCTATTACTGTATGCGCATTACTTGGATTTTGAGGGGCACTCTACCTTGGTTATGATTCAGTAGAGGAAAAAGACCACCT
TTCTTCAATTTACAAATTAAATCTTCTGGAGGGTCGCTATCACAAAACATTGACGATGTATGTATTATAATTTTTTAGAAAAACCACCAT
CGTGTCACGTCGACGATGCCAAATTATGTTAGCGTGAGCAGAAACACCGTGGGGGAGGAAGGCAGCAGCTGAAGAAAAAAGCTCAAATGA
TCTAGTCACTTTCGATACTGTACTTCAGATGCGAAATGGATATTCGAGTGGAAACCTGACAAAGTGCGCCTGCTTTGATGTGAACTGGTA
TAGACAATGACCAGTGGCTGGGTCAGTGGGATGTCTCTCTGTGAGCACAAAGGCTTATCAAATGACACTAAAAATAAGTTCAACAACCAT
CACATTGGAAGGGAGAAGGCGAACATTTCATGTTTGGCGGGCATGTGAGTGCACAAGATGGAAAGAGCGATTGGAGCATCCTGGTATAAT
TACCCCCATTGTGCTCTTAATGGAAATTTCAAAGGACGGGAGTATTCTGTTGGTTGGTGTCCAGGTTTGTGGCACTGTTCCAAGAGGCCT
TACACACACACACAAATATATAATTTTCTATACATATATATCCTCTAGCTTGAAACTTTTGCTCAAGTTTATTTATGTCACTGGCTGGCT
GGATCCAAAGTCATGTGTCCACACATTCATAAATAAAAATTTTACCTATGCCTGTGCTACCATTTCTTTAAGCCCACATAAAGCTAATGC
CTTCTTGGGTTGAATATGCAGTTGTTATGCTTAGTTTCAGGGATGGAATTCTATTCAGTTCCAAAATGTCCCTCATGTTCACAGATGATA
CTATTGGCAGTAGCTGCATATGCAAGTGTAACTTGGAAGCCTGATATAGTATACCCAACCCTTTCTGCAATGAGTTATTGTATCCCTTTG
TTCTGCATTTGCATCTGGAACAAGACCTAATGTGGCTTCCTTAAATGGGCACTTCATTTCTGATGAGTGCACACCAATTATTGCTATTTT
AATATCATTGAGAATACTACAGAAGCTAAGGCTATGTTTCTTTGGTAACTACTTCAAATTTCTCTAGAATTATGTAGCATACTTACATTT
TGCTGCATGAACAATGAAAATTAACCTCTGCCTTTAAATGGAAAAATAACTTTCTGTAGATTGTTATACAGCTACTATGAAGAGCTCTTA
ATGAAGAGGAAGTGGCAGTGGTCTATATGTAGACTGAAAAAATATCATTAATAAAGTTCAAAGACTGATGGAATTTCATTGCCCTTAAAG
ATATGAACCAGATCTGTTTTATGCTTTTCTCCAATTATACTAACTAGCAGTTGAAAAGAATTTGTTTTGAAGAGTGTTATTTTCTTACCA
AAAGACCAGATCAAAAATCCCTATACTTTTCCACCAAAAAAAGATTAAAATGAAGCCATTTCTATAAATTTAATGGCACTTTATATTTTA
TATAGAGAAATAGCTTCTGTTTGATTTTCTGGACACCATGTCAGTCAAGATCTACTTTCTGTGTAAAAATGAATAAGTCTTGCACATAAT
CCATTCGTGTTGCATAAGGTTGCAAAAACAATTAAGTGGGAAATGACTCCTAACTTATGTGTCTACTCTGCCTAGAAAGAAAGTTTTGAA
GGCATCTATATATATTTCATAACAATGTCTGTTCTTTATGGATTTGATCCATAAATATTTATCTATCTGAAAACTTTGATACTTGGAATG
TTTTCCTTAGAGCATTTGGTGCTCCAAGAAAAAACATTTGGTGCTAAGAGTTGCAGCACTGATGCCTTTCCCTAAGTTAATTCTATTTTA
AAAATTTATATTTCCTTCCCAATGAGATGCAGAGTAAAATTTGAGACCCTCCATTGACTAGGGAGCAGCATCTGTCATCTATGGTTAATT
ACTATTTTGACAAAAATATAGAAGGTTTAAACCCCCATGTATTTCAGATTGTTAGAGAAAGAAGTAGTTTGCTTATATTTCCCTTGAACT
TTATTCTAACCATTTAAATAATAAATTATTCAATATTTGTTATAATAAATCCTTACTAGATACAAGATTTGGGTGTTTCTGTGAAGTTAA
CTTTATTATCTAAATATCACTAACCATTGTTTACTGCTCAGAGGCAGATACATTTGTTTAGTTTAAAGTTGAAACAAATTCTATATTGTG
GATAATTAGGTGTTTAAAACATTTTGATAGACCAGCTTATATATGTTATTTTTGAAATTTAAGAAGGCAGAATGTAATTAGGTCACATTT
ACAAGTAGAAGGAATTATAACTTCCTACTCCATGCATATATTGTATATTGGTTAGCTTTTACTAGCATTTTCTAGCATCACATTACTTTA
GAAAGTTTTTGAGAGTTTCATTACTACTGGAAAAGTTTGGTGGGTATATGTACACAGGAAAGAAATATATGCATCATTTCAATATGAAAG
GAAATACATAATCTAGAAACATAGAATAACTCTTGGTACATCTGTTACATAGTTAAGGAAAGAAACAGGCAGGTGAGGCTGGAGAATGTT
GTCTATTTGTAGGAAATAAAGTCAGTGCAGACGCATATTCTAGTTTAGAGTTAGATTAATATTGTGCTTAGTGAATTTCTATGACATATT
TCTGAGAACACTTTAATATATTTCCACACCTACTGGAATCTAATTCAGTCGATCGGATAAAAGAAAGACTTTTTTGTTGTTGTTTTTGAA
AATCCATAATGTAGCAGGTTCTGCGCTGGTTTTTTAATGTATTTTATTTTTGTGCTCTCCTGCCAAAAGAAAAGGCTGATAAGTAAGTAC
ACAGTACAACATGTAAATTTGTATAAAAATATGCTTGTTTAGATTGCTCTACAATAACTATATTAAGGTAAATTGTGTGTGTGTGTGTGA
GAGAGAGAGAGAGAGAGAGAAACAGAGGGAGAATTGACTCAATGTGTTTTCTATGAAGAGTCTTAGCTTAGGAATCAGGTAACAGAGAGG
TCCTAGACCATAGACCCAGCCATCAACTAGCTTGCTGATGTTGAACAGATCAACTCTCAACCATAGACTGAAGATGGAATGAAGATATCA
AAAGTTCCTTTTAGCACTGACTAGATTTTTTTTCTTTTTTTTGAAACAGAGTCTCACTCTGTCACCCAGGCTGGAGTTCAATGGCATGGT
CTGGGCTGACTGTAACCTCCTCTTCCTGGGTTCAAGTGATTCTCATCCCTCAGCCTCCTGAGTAGCTGGGATTACAGGCACATAACACCA
CACCCAGCTAACTCTTGTATTTTTGTAGAAATGGGGTTTCGCTATGTTGCTCAGACTGGTCTCAAACACCTGGCCTCAAGTGATCCTCCT
GCCTCAGTCTCCCAAATGCTGTGATTACAGGCACAAGCTACTGCACCAGGCCTCTGACTACATTTCTATTAATATGGTTAGGTTGGAGGT
TTTAGTATTTTTGTATCTCATATTTGTATCAATATGACTGGCTTCTTTGTCTGTAGTGTGTGGTAATATTAGTTCTGTAAACTGTCAGTT
GCAAAAAAAAAAAATACCTTGAACTATAGTATATGTTGATAATTAGCCATAATAATTTCTTAGTTAATTTCTTATAATTAAATTTGTCAA
AGAGGAAACTTACAGTTTATATCTGATGAAATCTCTAAAAAGATGGGTAAAACATTGGGAAATGTATGCATGTACTTCACTCTGGTTTCA
TAGGGTTAGCAAGTGTCTTAAAAACATATATAAAGAAGCACAGAGATTGTTAGGAGATATTTATGCTCCCAGTTTTAATAATTGGGATAC
TTTGTATACCACAGAAAGAAAAATTACTAAACTCCTCTTTTTTTAGTCAAAATTGGAAAAAAAGTCTTAATTGACAGTTACTATGCCTGT
GCTACCCATAGCAAGTATTCAGTGGAAAATACTTTACTAAGTAAGTAATTTGAACACAGCTTAAAATCCATAGTATGTTACAATTGCTAG
CCTTTCACAAAGTTTGCATTGTCTTAATGTAGAAGGATACTGTGATCTAAGAATTCACAATTTTAAAAAGTGGAACCTAAATAGGGTTTC
CTAATTGCCATGAAGTTATTTGTATCTTAGATGAATTATATTTACAACATTGTAAATGTCAGTGGGTGATCCAAAATAAATTGTTAAAGT
TATTAAAATGTACATTTAAGTAGGTTTCAGTTTGACTAGAAATAATTGGCAAGAAGGCAAGAACTAGTCTTCTAGAGCAGGGATCCCATC
CCCCAGGTCATGGACTGGTACTGGTCCATGGCCTGTTAGAAACCAGGCCACACAGCAGGAGATGAGTGGAAAGCAAGTGAAACTTCATGG
GTATTTACAGCAATTCCCCGTCGCTCGCATTACCACCTGAGCTGTGTCTCCTGTGAGATCAGCAGCAGCATTAGATTCTCAAGGAGCACA
AACCCTTTTGGAACTGTGTGTGAGGGATCTAAGTTGCGCATTTCTTATGAGAATCTAATACCTGATGATCTGTTGTTGTCTCCCACCACC
CCCAGATGGGACCATCTAGTTGCAGGAAAACAAGCTCAGGCTCCCACTGATTCTACATTATAGTGAGTTGTGTAATTATTTCATTATATA
TAACAATGTAATAATAATAGAAATAAAGTACATAATAAATGTAATCCACTTGAATTATCCTGAAACCATCCCCACCCCCCACCCCCCGGT
CTGTGGAAAAATTGGCTTCCACGAAACTGGTCCGTGGTGCCAAAAATATTGGGTATGGTTGTTCTAGGGTGTAGACTATGAAAAAGATAT
GCATTGTCTCCATGAACTAAAAGGCAAGGTGATTTTAAACAATTTAGATGCCAAACAAAGAAACCAAAAGCTTCCAAAGTAATAAATGAT
AGAGAAAGGAAATTGTTACATCATGTGCCAAATTAGAAGCAAATCTAAACTTCTTATCATGTACTCCACCATCTGATTTGTATAAGTAAT
TGGGGAAAGAAAAACTCACAATATAAAACAAGATTGACTAGTTCTAGCAGATGACACCTGTAAATAGAATTTTTACTAGTTGAAATTCTG

>62655_62655_2_PAQR3-ANTXR2_PAQR3_chr4_79847675_ENST00000512733_ANTXR2_chr4_80906017_ENST00000403729_length(amino acids)=422AA_BP=280
MGSSGSAVGPRAASAGSGAGAPAAKPPPRGGGTWGSSRAGERRRPGTMHQKLLKSAHYIELGSYQYWPVLVPRGIRLYTYEQIPGSLKDN
PYITDGYRAYLPSRLCIKSLFILSNETVNIWSHLLGFFLFFTLGIYDMTSVLPSASASREDFVICSICLFCFQVCMLCSVGYHLFSCHRS
EKTCRRWMALDYAGISIGILGCYVSGVFYAFYCNNYWRQVYLITVLAMILAVFFAQIHPNYLTQQWQRLRSIIFCSVSGYGVIPTLHWVW
LNGGIGAPIVQVIKDPPPPPAPAPKEEEEEPLPTKKWPTVDASYYGGRGVGGIKRMEVRWGDKGSTEEGARLEKAKNAVVKIPEETEEPI

--------------------------------------------------------------

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Fusion Gene PPI Analysis for PAQR3-ANTXR2


check button Go to ChiPPI (Chimeric Protein-Protein interactions) to see the chimeric PPI interaction in

ChiPPI page.


check button Protein-protein interactors with each fusion partner protein in wild-type (BIOGRID-3.4.160)
HgeneHgene's interactorsTgeneTgene's interactors


check button - Retained PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenStill interaction with


check button - Lost PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


check button - Retained PPIs, but lost function due to frame-shift fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


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Related Drugs for PAQR3-ANTXR2


check button Drugs targeting genes involved in this fusion gene.
(DrugBank Version 5.1.8 2021-05-08)
PartnerGeneUniProtAccDrugBank IDDrug nameDrug activityDrug typeDrug status

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Related Diseases for PAQR3-ANTXR2


check button Diseases associated with fusion partners.
(DisGeNet 4.0)
PartnerGeneDisease IDDisease name# pubmedsSource