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Center for Computational Systems Medicine
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Fusion Gene Summary

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Fusion Gene ORF analysis

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Fusion Genomic Features

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Fusion Protein Features

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Fusion Gene Sequence

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Fusion Gene PPI analysis

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Related Drugs

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Related Diseases

Fusion gene:PARP6-MYO9A (FusionGDB2 ID:62842)

Fusion Gene Summary for PARP6-MYO9A

check button Fusion gene summary
Fusion gene informationFusion gene name: PARP6-MYO9A
Fusion gene ID: 62842
HgeneTgene
Gene symbol

PARP6

MYO9A

Gene ID

56965

4649

Gene namepoly(ADP-ribose) polymerase family member 6myosin IXA
SynonymsARTD17|PARP-6-B1|PARP-6-C|pART17CMS24
Cytomap

15q23

15q23

Type of geneprotein-codingprotein-coding
Descriptionprotein mono-ADP-ribosyltransferase PARP6ADP-ribosyltransferase diphtheria toxin-like 17PARP-6poly [ADP-ribose] polymerase 6unconventional myosin-IXamyosin-IXaunconventional myosin-9a
Modification date2020032020200313
UniProtAcc.

B2RTY4

Ensembl transtripts involved in fusion geneENST00000260376, ENST00000287196, 
ENST00000569795, ENST00000413097, 
ENST00000563542, ENST00000356056, 
ENST00000424560, ENST00000444904, 
ENST00000564571, ENST00000566885, 
Fusion gene scores* DoF score1 X 1 X 1=110 X 10 X 4=400
# samples 110
** MAII scorelog2(1/1*10)=3.32192809488736log2(10/400*10)=-2
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0
Context

PubMed: PARP6 [Title/Abstract] AND MYO9A [Title/Abstract] AND fusion [Title/Abstract]

Most frequent breakpointMYO9A(72410021)-PARP6(72535040), # samples:3
PARP6(72545778)-MYO9A(72260466), # samples:2
Anticipated loss of major functional domain due to fusion event.MYO9A-PARP6 seems lost the major protein functional domain in Hgene partner, which is a essential gene due to the frame-shifted ORF.
MYO9A-PARP6 seems lost the major protein functional domain in Tgene partner, which is a essential gene due to the frame-shifted ORF.
PARP6-MYO9A seems lost the major protein functional domain in Hgene partner, which is a essential gene due to the frame-shifted ORF.
PARP6-MYO9A seems lost the major protein functional domain in Tgene partner, which is a essential gene due to the frame-shifted ORF.
* DoF score (Degree of Frequency) = # partners X # break points X # cancer types
** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10)

check button Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez
PartnerGeneGO IDGO termPubMed ID
HgenePARP6

GO:0070213

protein auto-ADP-ribosylation

25043379


check buttonFusion gene breakpoints across PARP6 (5'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.
all structure

check buttonFusion gene breakpoints across MYO9A (3'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.
all structure

check button Fusion gene information from two resources (ChiTars 5.0 and ChimerDB 4.0)
* All genome coordinats were lifted-over on hg19.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
SourceDiseaseSampleHgeneHchrHbpHstrandTgeneTchrTbpTstrand
ChimerDB4LUADTCGA-86-8358-01APARP6chr15

72545778

-MYO9Achr15

72260466

-


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Fusion Gene ORF analysis for PARP6-MYO9A

check button Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
ORFHenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrand
5CDS-5UTRENST00000260376ENST00000563542PARP6chr15

72545778

-MYO9Achr15

72260466

-
5CDS-5UTRENST00000287196ENST00000563542PARP6chr15

72545778

-MYO9Achr15

72260466

-
5CDS-5UTRENST00000569795ENST00000563542PARP6chr15

72545778

-MYO9Achr15

72260466

-
5UTR-3CDSENST00000413097ENST00000356056PARP6chr15

72545778

-MYO9Achr15

72260466

-
5UTR-3CDSENST00000413097ENST00000424560PARP6chr15

72545778

-MYO9Achr15

72260466

-
5UTR-3CDSENST00000413097ENST00000444904PARP6chr15

72545778

-MYO9Achr15

72260466

-
5UTR-3CDSENST00000413097ENST00000564571PARP6chr15

72545778

-MYO9Achr15

72260466

-
5UTR-3CDSENST00000413097ENST00000566885PARP6chr15

72545778

-MYO9Achr15

72260466

-
5UTR-5UTRENST00000413097ENST00000563542PARP6chr15

72545778

-MYO9Achr15

72260466

-
Frame-shiftENST00000260376ENST00000356056PARP6chr15

72545778

-MYO9Achr15

72260466

-
Frame-shiftENST00000260376ENST00000424560PARP6chr15

72545778

-MYO9Achr15

72260466

-
Frame-shiftENST00000260376ENST00000444904PARP6chr15

72545778

-MYO9Achr15

72260466

-
Frame-shiftENST00000260376ENST00000564571PARP6chr15

72545778

-MYO9Achr15

72260466

-
Frame-shiftENST00000260376ENST00000566885PARP6chr15

72545778

-MYO9Achr15

72260466

-
Frame-shiftENST00000569795ENST00000356056PARP6chr15

72545778

-MYO9Achr15

72260466

-
Frame-shiftENST00000569795ENST00000424560PARP6chr15

72545778

-MYO9Achr15

72260466

-
Frame-shiftENST00000569795ENST00000444904PARP6chr15

72545778

-MYO9Achr15

72260466

-
Frame-shiftENST00000569795ENST00000564571PARP6chr15

72545778

-MYO9Achr15

72260466

-
Frame-shiftENST00000569795ENST00000566885PARP6chr15

72545778

-MYO9Achr15

72260466

-
In-frameENST00000287196ENST00000356056PARP6chr15

72545778

-MYO9Achr15

72260466

-
In-frameENST00000287196ENST00000424560PARP6chr15

72545778

-MYO9Achr15

72260466

-
In-frameENST00000287196ENST00000444904PARP6chr15

72545778

-MYO9Achr15

72260466

-
In-frameENST00000287196ENST00000564571PARP6chr15

72545778

-MYO9Achr15

72260466

-
In-frameENST00000287196ENST00000566885PARP6chr15

72545778

-MYO9Achr15

72260466

-

check buttonORFfinder result based on the fusion transcript sequence of in-frame fusion genes.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandSeq length
(transcript)		BP loci
(transcript)		Predicted start
(transcript)		Predicted stop
(transcript)		Seq length
(amino acids)
ENST00000287196PARP6chr1572545778-ENST00000356056MYO9Achr1572260466-11810171845975202353
ENST00000287196PARP6chr1572545778-ENST00000444904MYO9Achr1572260466-8073171845975202353
ENST00000287196PARP6chr1572545778-ENST00000424560MYO9Achr1572260466-8286171845977332424
ENST00000287196PARP6chr1572545778-ENST00000564571MYO9Achr1572260466-7825171845970642201
ENST00000287196PARP6chr1572545778-ENST00000566885MYO9Achr1572260466-5562171845949941511

check buttonDeepORF prediction of the coding potential based on the fusion transcript sequence of in-frame fusion genes. DeepORF is a coding potential classifier based on convolutional neural network by comparing the real Ribo-seq data. If the no-coding score < 0.5 and coding score > 0.5, then the in-frame fusion transcript is predicted as being likely translated.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandNo-coding scoreCoding score
ENST00000287196ENST00000356056PARP6chr1572545778-MYO9Achr1572260466-0.0002910760.99970895
ENST00000287196ENST00000444904PARP6chr1572545778-MYO9Achr1572260466-0.0008761470.9991239
ENST00000287196ENST00000424560PARP6chr1572545778-MYO9Achr1572260466-0.0010139280.99898607
ENST00000287196ENST00000564571PARP6chr1572545778-MYO9Achr1572260466-0.0015910930.998409
ENST00000287196ENST00000566885PARP6chr1572545778-MYO9Achr1572260466-0.0006120030.999388

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Fusion Genomic Features for PARP6-MYO9A


check buttonFusionAI prediction of the potential fusion gene breakpoint based on the pre-mature RNA sequence context (+/- 5kb of individual partner genes, total 20kb length sequence). FusionAI is a fusion gene breakpoint classifier based on convolutional neural network by comparing the fusion positive and negative sequence context of ~ 20K fusion gene data. From here, we can have the relative potentency of the 20K genomic sequence how individual sequnce will be likely used as the gene fusion breakpoints.
HgeneHchrHbpHstrandTgeneTchrTbpTstrand1-pp (fusion gene breakpoint)

check buttonDistribution of 44 human genomic features loci across 20kb length fusion breakpoint regions. We integrated a total of 44 different types of human genomic feature loci information across five big categories including virus integration sites, repeats, structural variants, chromatin states, and gene expression regulation. More details are in help page.
genomic feature

check buttonDistribution of 44 human genomic features loci across 20kb length fusion breakpoint regions that are ovelapped with the top 1% feature importance score regions. More details are in help page.

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Fusion Protein Features for PARP6-MYO9A


check button Four levels of functional features of fusion genes
Go to FGviewer search page for the most frequent breakpoint (https://ccsmweb.uth.edu/FGviewer/chr15:72410021/chr15:72535040)
- FGviewer provides the online visualization of the retention search of the protein functional features across DNA, RNA, protein, and pathological levels.
- How to search
1. Put your fusion gene symbol.
2. Press the tab key until there will be shown the breakpoint information filled.
4. Go down and press 'Search' tab twice.
4. Go down to have the hyperlink of the search result.
5. Click the hyperlink.
6. See the FGviewer result for your fusion gene.
FGviewer

check buttonMain function of each fusion partner protein. (from UniProt)
HgeneTgene
.MYO9A

B2RTY4

FUNCTION: Transcriptional activator which is required for calcium-dependent dendritic growth and branching in cortical neurons. Recruits CREB-binding protein (CREBBP) to nuclear bodies. Component of the CREST-BRG1 complex, a multiprotein complex that regulates promoter activation by orchestrating a calcium-dependent release of a repressor complex and a recruitment of an activator complex. In resting neurons, transcription of the c-FOS promoter is inhibited by BRG1-dependent recruitment of a phospho-RB1-HDAC1 repressor complex. Upon calcium influx, RB1 is dephosphorylated by calcineurin, which leads to release of the repressor complex. At the same time, there is increased recruitment of CREBBP to the promoter by a CREST-dependent mechanism, which leads to transcriptional activation. The CREST-BRG1 complex also binds to the NR2B promoter, and activity-dependent induction of NR2B expression involves a release of HDAC1 and recruitment of CREBBP (By similarity). {ECO:0000250}.FUNCTION: Myosins are actin-based motor molecules with ATPase activity. Unconventional myosins serve in intracellular movements. Regulates Rho by stimulating it's GTPase activity in neurons. Required for the regulation of neurite branching and motor neuron axon guidance (By similarity). {ECO:0000250|UniProtKB:Q8C170, ECO:0000250|UniProtKB:Q9Z1N3}.

check buttonRetention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at

download page


* Minus value of BPloci means that the break pointn is located before the CDS.
- In-frame and retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
TgeneMYO9Achr15:72545778chr15:72260466ENST0000035605611421264_12916142549.0Coiled coilOntology_term=ECO:0000255
TgeneMYO9Achr15:72545778chr15:72260466ENST0000035605611421486_15326142549.0Coiled coilOntology_term=ECO:0000255
TgeneMYO9Achr15:72545778chr15:72260466ENST0000035605611422315_23586142549.0Coiled coilOntology_term=ECO:0000255
TgeneMYO9Achr15:72545778chr15:72260466ENST0000042456011431264_12916142620.0Coiled coilOntology_term=ECO:0000255
TgeneMYO9Achr15:72545778chr15:72260466ENST0000042456011431486_15326142620.0Coiled coilOntology_term=ECO:0000255
TgeneMYO9Achr15:72545778chr15:72260466ENST0000042456011432315_23586142620.0Coiled coilOntology_term=ECO:0000255
TgeneMYO9Achr15:72545778chr15:72260466ENST0000044490410411264_12915952530.0Coiled coilOntology_term=ECO:0000255
TgeneMYO9Achr15:72545778chr15:72260466ENST0000044490410411486_15325952530.0Coiled coilOntology_term=ECO:0000255
TgeneMYO9Achr15:72545778chr15:72260466ENST0000044490410412315_23585952530.0Coiled coilOntology_term=ECO:0000255
TgeneMYO9Achr15:72545778chr15:72260466ENST0000035605611421021_10416142549.0DomainIQ 1
TgeneMYO9Achr15:72545778chr15:72260466ENST0000035605611421042_10716142549.0DomainIQ 2
TgeneMYO9Achr15:72545778chr15:72260466ENST0000035605611421074_11036142549.0DomainIQ 3
TgeneMYO9Achr15:72545778chr15:72260466ENST0000035605611421115_11446142549.0DomainIQ 4
TgeneMYO9Achr15:72545778chr15:72260466ENST0000035605611421138_11676142549.0DomainIQ 5
TgeneMYO9Achr15:72545778chr15:72260466ENST0000035605611422063_22516142549.0DomainRho-GAP
TgeneMYO9Achr15:72545778chr15:72260466ENST0000042456011431021_10416142620.0DomainIQ 1
TgeneMYO9Achr15:72545778chr15:72260466ENST0000042456011431042_10716142620.0DomainIQ 2
TgeneMYO9Achr15:72545778chr15:72260466ENST0000042456011431074_11036142620.0DomainIQ 3
TgeneMYO9Achr15:72545778chr15:72260466ENST0000042456011431115_11446142620.0DomainIQ 4
TgeneMYO9Achr15:72545778chr15:72260466ENST0000042456011431138_11676142620.0DomainIQ 5
TgeneMYO9Achr15:72545778chr15:72260466ENST0000042456011432063_22516142620.0DomainRho-GAP
TgeneMYO9Achr15:72545778chr15:72260466ENST0000044490410411021_10415952530.0DomainIQ 1
TgeneMYO9Achr15:72545778chr15:72260466ENST0000044490410411042_10715952530.0DomainIQ 2
TgeneMYO9Achr15:72545778chr15:72260466ENST0000044490410411074_11035952530.0DomainIQ 3
TgeneMYO9Achr15:72545778chr15:72260466ENST0000044490410411115_11445952530.0DomainIQ 4
TgeneMYO9Achr15:72545778chr15:72260466ENST0000044490410411138_11675952530.0DomainIQ 5
TgeneMYO9Achr15:72545778chr15:72260466ENST0000044490410412063_22515952530.0DomainRho-GAP
TgeneMYO9Achr15:72545778chr15:72260466ENST0000035605611421021_11626142549.0RegionNote=Neck or regulatory domain
TgeneMYO9Achr15:72545778chr15:72260466ENST0000035605611421163_25116142549.0RegionNote=Tail
TgeneMYO9Achr15:72545778chr15:72260466ENST000003560561142898_9206142549.0RegionActin-binding
TgeneMYO9Achr15:72545778chr15:72260466ENST0000042456011431021_11626142620.0RegionNote=Neck or regulatory domain
TgeneMYO9Achr15:72545778chr15:72260466ENST0000042456011431163_25116142620.0RegionNote=Tail
TgeneMYO9Achr15:72545778chr15:72260466ENST000004245601143898_9206142620.0RegionActin-binding
TgeneMYO9Achr15:72545778chr15:72260466ENST0000044490410411021_11625952530.0RegionNote=Neck or regulatory domain
TgeneMYO9Achr15:72545778chr15:72260466ENST0000044490410411163_25115952530.0RegionNote=Tail
TgeneMYO9Achr15:72545778chr15:72260466ENST000004449041041898_9205952530.0RegionActin-binding
TgeneMYO9Achr15:72545778chr15:72260466ENST0000035605611421999_20486142549.0Zinc fingerPhorbol-ester/DAG-type 1
TgeneMYO9Achr15:72545778chr15:72260466ENST0000035605611422068_21196142549.0Zinc fingerPhorbol-ester/DAG-type 2
TgeneMYO9Achr15:72545778chr15:72260466ENST0000042456011431999_20486142620.0Zinc fingerPhorbol-ester/DAG-type 1
TgeneMYO9Achr15:72545778chr15:72260466ENST0000042456011432068_21196142620.0Zinc fingerPhorbol-ester/DAG-type 2
TgeneMYO9Achr15:72545778chr15:72260466ENST0000044490410411999_20485952530.0Zinc fingerPhorbol-ester/DAG-type 1
TgeneMYO9Achr15:72545778chr15:72260466ENST0000044490410412068_21195952530.0Zinc fingerPhorbol-ester/DAG-type 2

- In-frame and not-retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
HgenePARP6chr15:72545778chr15:72260466ENST00000260376-1522394_620419509.0DomainPARP catalytic
HgenePARP6chr15:72545778chr15:72260466ENST00000287196-1523394_620419631.0DomainPARP catalytic
HgenePARP6chr15:72545778chr15:72260466ENST00000569795-1624394_620419631.0DomainPARP catalytic
TgeneMYO9Achr15:72545778chr15:72260466ENST000003560561142146_10166142549.0DomainMyosin motor
TgeneMYO9Achr15:72545778chr15:72260466ENST00000356056114214_1126142549.0DomainRas-associating
TgeneMYO9Achr15:72545778chr15:72260466ENST000004245601143146_10166142620.0DomainMyosin motor
TgeneMYO9Achr15:72545778chr15:72260466ENST00000424560114314_1126142620.0DomainRas-associating
TgeneMYO9Achr15:72545778chr15:72260466ENST000004449041041146_10165952530.0DomainMyosin motor
TgeneMYO9Achr15:72545778chr15:72260466ENST00000444904104114_1125952530.0DomainRas-associating
TgeneMYO9Achr15:72545778chr15:72260466ENST000003560561142239_2466142549.0Nucleotide bindingATP
TgeneMYO9Achr15:72545778chr15:72260466ENST000004245601143239_2466142620.0Nucleotide bindingATP
TgeneMYO9Achr15:72545778chr15:72260466ENST000004449041041239_2465952530.0Nucleotide bindingATP
TgeneMYO9Achr15:72545778chr15:72260466ENST000003560561142175_1956142549.0TransmembraneHelical
TgeneMYO9Achr15:72545778chr15:72260466ENST000004245601143175_1956142620.0TransmembraneHelical
TgeneMYO9Achr15:72545778chr15:72260466ENST000004449041041175_1955952530.0TransmembraneHelical


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Fusion Gene Sequence for PARP6-MYO9A


check button For in-frame fusion transcripts, we provide the fusion transcript sequences and fusion amino acid sequences. To have fusion amino acid sequence, we ran ORFfinder and chose the longest ORF among the all predicted ones.
>62842_62842_1_PARP6-MYO9A_PARP6_chr15_72545778_ENST00000287196_MYO9A_chr15_72260466_ENST00000356056_length(transcript)=11810nt_BP=1718nt
CAACAGAAACCAAGCAGCAACAGCCCTTGGAAAGAGGCTAAATTTTTCTTGACTTCTGCAGCAACAAAGACCGTGAAAAGTTGGCACTTC
TGGCCTAACGCTGCCGTCATCCTACCCCTCACCCCAGGGCAACCCAGGCTGGACATTTAGTGCCTCCCTCTTTATTCCTCTGTGATCATC
CAGATCAGCACTTGACTGTTTATTTTCAAATCTCACGAACCTCACCCCAAGATCTTCACATTCTGGATCTCAGCTGCTCTTGAAGGACAG
TGACTTGTTACCACCGCAACAGCAGAGCCTGCCATCCCCAACAGATCACCAGTTGTCCCTGACATCGTGCCCTACCTTGTCTCCCTTTGT
GGTCTCCTAAATGCCCATCTCGTTGGCCTTGGTTCGGCTAGTGGTATGGAGGGGTGCTGCCTAGCACTGACCTGAGAGTGTGTGTGACCC
ACTGACCCAATGGACATCAAAGGCCAGTTCTGGAATGATGACGACTCGGAGGGAGATAATGAATCAGAGGAATTTCTCTATGGCGTTCAG
GGGAGCTGTGCAGCTGACCTGTATCGACACCCACAGCTTGATGCAGACATTGAAGCCGTGAAGGAGATCTACAGTGAGAACTCTGTATCC
ATCAGAGAATATGGAACTATCGATGACGTGGACATTGACCTCCACATCAACATCAGCTTCCTCGATGAGGAAGTCTCTACAGCCTGGAAG
GTCCTCCGGACAGAACCTATTGTGTTGAGGCTGCGATTTTCTCTCTCCCAGTACCTAGATGGACCAGAACCATCCATTGAGGTTTTCCAG
CCATCAAATAAGGAAGGATTTGGGCTGGGTCTTCAGTTGAAAAAGATCCTGGGTATGTTTACATCCCAACAATGGAAACATCTGAGCAAT
GATTTCTTGAAGACCCAGCAGGAGAAGAGGCACAGTTGGTTCAAGGCAAGTGGTACCATCAAGAAGTTCCGAGCTGGCCTCAGCATCTTT
TCACCCATCCCCAAGTCTCCCAGTTTCCCTATCATACAGGACTCCATGCTGAAAGGCAAACTAGGTGTACCAGAGCTTCGGGTTGGGCGC
CTCATGAACCGTTCCATCTCCTGTACCATGAAGAACCCCAAAGTGGAAGTGTTTGGCTACCCTCCCAGCCCCCAGGCAGGTCTCCTGTGC
CCTCAGCACGTGGGCCTCCCTCCCCCAGCACGGACCTCTCCTTTGGTCAGTGGTCACTGCAAGAACATTCCCACTCTGGAGTATGGATTC
CTCGTTCAGATCATGAAGTATGCAGAACAGAGGATTCCAACATTGAATGAGTACTGTGTGGTGTGTGATGAGCAGCATGTCTTCCAAAAT
GGATCTATGCTGAAGCCAGCTGTCTGTACTCGTGAACTATGCGTTTTCTCCTTCTACACACTGGGCGTCATGTCTGGAGCTGCAGAGGAG
GTGGCCACTGGAGCAGAGGTGGTGGATCTGCTGGTGGCCATGTGTAGGGCAGCTTTAGAGTCCCCTAGAAAGAGCATCATCTTTGAGCCT
TATCCCTCTGTGGTGGACCCCACTGATCCCAAGACTCTGGCCTTTAACCCTAAGAAGAAGAATTATGAGCGGCTTCAGAAAGCTCTGGAT
AGTGTGATGTCTATTCGGGAGATGACCCAGGGCTCATATTTGGAAATCAAGAAACAGATGGACAAGTTGGATCCCCTGGCCCATCCTCTC
CTGCAGTGCTTTCCACAGGCTACAAATCAAACATTGCTAGACAAGTTTAAGCATCAACATGAAGATAATTCTTACATCGAATTTCCAGCC
GTGATGGAGCCTGCTTTCATTATAAAACATTATGCTGGAAAAGTAAAATATGGGGTAAAGGATTTCCGGGAAAAAAATACAGATCATATG
CGCCCAGACATTGTAGCTCTTCTGAGAAGCAGCAAGAATGCATTTATCTCTGGGATGATTGGAATTGATCCTGTAGCTGTTTTCCGATGG
GCAATTCTCCGAGCTTTTTTCAGAGCCATGGTTGCTTTCAGGGAAGCTGGGAAAAGAAACATTCACAGAAAAACTGGACATGATGATACA
GCGCCATGTGCAATTTTGAAAAGTATGGATAGTTTTAGCTTTCTCCAACACCCAGTCCACCAGAGGAGCTTAGAGATTCTGCAGAGATGC
AAGGAAGAGAAGTACAGTATAACCCGGAAAAATCCCAGAACACCTCTTTCTGATCTCCAGGGCATGAATGCTCTAAATGAAAAAAACCAA
CATGATACATTTGATATTGCCTGGAATGGCAGAACTGGGATTCGCCAGAGCAGACTATCAAGTGGCACCTCCTTGCTTGATAAAGATGGA
ATATTTGCTAATTCAACTAGCAGCAAACTCCTGGAGAGAGCCCATGGAATTCTCACGAGAAACAAAAATTTCAAATCCAAGCCTGCCCTT
CCAAAGCACTTGCTAGAAGTAAATTCTTTAAAGCACCTGACAAGACTGACACTACAAGATCGCATTACCAAGTCTCTTCTTCATTTACAC
AAGAAGAAAAAACCTCCCAGCATCAGTGCCCAGTTTCAGGCATCATTAAGCAAGCTAATGGAAACACTTGGTCAAGCAGAACCATATTTT
GTAAAATGCATTCGCTCTAATGCTGAAAAGCTGCCCTTAAGGTTCAGTGATGTCTTGGTACTTAGACAGCTTCGATACACCGGGATGCTG
GAAACAGTTCGAATTCGCCAATCAGGATACAGCTCCAAATATTCTTTCCAGGATTTTGTGAGCCACTTCCATGTACTTCTTCCCCGAAAT
ATTATTCCATCCAAATTTAACATTCAGGATTTCTTCAGGAAAATAAATCTTAATCCAGATAATTATCAAGTTGGAAAAACCATGGTCTTT
CTAAAGGAGCAGGAACGACAGCACTTACAAGATCTGCTTCACCAAGAGGTGCTCCGCAGAATCATATTGTTGCAGCGATGGTTCAGGGTC
TTGCTGTGTAGGCAGCATTTCCTCCATCTGAGACAAGCATCTGTTATTATCCAGAGATTCTGGAGGAATTACCTAAATCAGAAGCAAGTC
AGAGATGCAGCTGTGCAGAAGGATGCTTTTGTTATGGCTAGTGCAGCTGCTCTTCTCCAAGCTTCCTGGCGTGCTCACTTAGAGAGGCAG
CGGTACTTGGAGTTACGGGCTGCAGCCATCGTTATCCAGCAGAAATGGAGAGATTACTATAGGCGCAGGCACATGGCTGCTATTTGCATA
CAAGCAAGATGGAAAGCCTACAGGGAAAGTAAAAGGTACCAAGAACAAAGGAAAAAAATTATCCTTTTGCAATCAACATGTAGAGGATTC
AGAGCAAGACAAAGATTTAAAGCTTTAAAAGAACAAAGGCTAAGAGAAACAAAGCCAGAAGTTGGATTGGTGAATATTAAGGGATATGGA
TCTCTGGAAATTCAGGGTTCAGACCCTTCAGGATGGGAGGATTGTTCTTTTGACAACAGAATAAAAGCCATAGAGGAATGTAAATCTGTA
ATAGAGAGTAATCGAATTAGCCGTGAAAGTTCAGTGGACTGCTTGAAGGAGTCACCAAACAAGCAGCAGGAGAGAGCCCAAAGCCAGAGT
GGTGTGGACTTGCAGGAAGATGTGCTTGTAAGAGAGAGACCCAGATCCTTGGAGGATCTCCATCAGAAAAAAGTAGGCCGGGCTAAGAGA
GAAAGTAGGAGAATGAGAGAACTAGAGCAAGCTATATTTAGCTTAGAATTGCTGAAAGTTCGTTCTCTTGGTGGTATTTCTCCTTCAGAG
GATCGCAGATGGTCTACAGAATTGGTGCCTGAAGGCCTTCAGTCTCCACGGGGTACACCTGATAGTGAGAGCTCTCAAGGAAGCTTGGAA
CTTCTGAGCTATGAGGAAAGCCAAAAGAGCAAACTAGAGTCTGTCATTTCAGATGAAGGAGACTTGCAGTTTCCATCACCTAAGATATCC
AGCAGTCCAAAATTTGATTCACGGGACAATGCCCTCAGTGCCTCAAATGAGACTAGCAGTGCAGAGCATTTGAAGGATGGAACTATGAAG
GAAATGGTGGTCTGCAGTTCTGAGTCTATTACCTGTAAACCACAGCTGAAAGACTCCTTCATTTCAAATAGTCTACCTACTTTTTTTTAT
ATCCCCCAACAAGACCCACTGAAAACAAATTCCCAACTAGACACAAGTATCCAAAGAAACAAACTATTGGAAAATGAAGACACAGCGGGG
GAAGCTCTTACTTTGGATATCAACAGGGAAACTAGAAGGTATCACTGCTCAGGAAAAGATCAGATTGTTCCTTCTTTGAATACAGAGTCT
TCTAATCCTGTGCTTAAGAAGTTAGAAAAGCTAAACACTGAGAAGGAAGAAAGGCAAAAACAGTTGCAGCAACAGAATGAAAAAGAGATG
ATGGAACAGATTCGCCAGCAAACAGATATTTTAGAGAAGGAGCGCAAAGCCTTCAAGACAATTGAAAAGCCAAGAATTGGAGAGTGTTTG
GTGGCACCATCTTCCTATCAGTCAAAGCAAAGAGTAGAGAGGCCATCCTCTCTCCTCAGCTTAAATACCTCAAATAAGGGAGAACTTAAT
GTACTGGGGTCCCTATCATTAAAAGATGCAGCTCTTGCCCAAAAAGACAGTTCCTCTGCTCACTTACCCCCAAAGGACCGACCTGTCACC
GTGTTCTTTGAAAGAAAAGGAAGTCCATGCCAATCTAGTACTGTCAAGGAATTATCCAAGACAGACAGAATGGGCACCCAGCTGAATGTA
GCCTGTAAACTCTCAAATAATCGCATTTCAAAAAGAGAACACTTTAGGCCAACTCAGTCTTACAGCCACAATTCTGATGACCTTTCCAGA
GAGGGAAATGCTAGGCCCATTTTCTTCACTCCAAAGGACAATATGAGTATTCCCCTTGTCAGCAAAGAAGCCTTAAACAGTAAAAATCCT
CAACTCCATAAAGAAGATGAACCAGCATGGAAACCTGTGAAGTTAGCTGGGCCAGGCCAAAGAGAGACATCACAGCGATTTTCGTCAGTT
GATGAACAAGCAAAACTTCATAAGACTATGTCTCAAGGAGAGATTACCAAGTTGGCAGTGAGACAGAAGGCTTCAGATTCAGATATAAGA
CCTCAGAGAGCTAAGATGAGATTCTGGGCCAAAGGGAAACAAGGGGAGAAGAAGACTACCAGAGTGAAACCTACTACCCAGTCAGAGGTT
TCGCCACTCTTTGCAGGCACAGATGTGATTCCAGCTCATCAGTTTCCAGATGAATTAGCTGCATATCACCCAACACCTCCTTTGAGCCCA
GAACTGCCCGGCAGTTGCCGGAAGGAATTCAAAGAGAACAAAGAACCTTCTCCAAAGGCTAAGCGCAAGCGAAGTGTGAAGATTAGCAAC
GTGGCTTTGGATTCTATGCATTGGCAAAATGACTCTGTCCAGATCATAGCAAGTGTCAGTGATTTAAAAAGCATGGATGAATTTCTTCTG
AAAAAGGTGAATGACCTAGATAATGAAGACAGCAAGAAGGATACACTAGTGGATGTTGTATTTAAAAAAGCCCTGAAGGAATTTCGGCAG
AATATCTTCAGCTTTTATTCATCTGCATTGGCGATGGATGATGGGAAAAGCATACGGTATAAAGACCTCTATGCACTATTTGAACAGATT
CTGGAAAAGACGATGAGGCTTGAGCAGCGTGATTCACTGGGTGAATCTCCAGTGAGAGTTTGGGTCAACACTTTTAAAGTGTTTTTAGAT
GAATATATGAATGAATTCAAGACTTCAGATTGCACAGCCACAAAGGTGCCAAAAACAGAAAGAAAGAAAAGAAGGAAAAAGGAAACTGAT
TTGGTGGAAGAACACAATGGTCACATCTTTAAAGCCACCCAATATAGCATCCCTACATACTGTGAATACTGTTCTTCTTTGATATGGATA
ATGGACCGAGCCTCTGTTTGCAAATTATGCAAGTATGCTTGCCATAAGAAGTGCTGTCTGAAAACCACAGCCAAGTGCTCTAAAAAGTAT
GATCCAGAGCTGTCATCTCGACAATTTGGGGTTGAACTGTCCCGTTTGACCAGTGAAGACCGAACTGTTCCTTTAGTAGTGGAAAAGCTC
ATAAACTACATTGAAATGCATGGACTGTATACAGAAGGTATTTATCGAAAGTCTGGTTCGACTAATAAAATCAAGGAGCTTCGGCAGGGT
CTAGATACAGATGCTGAGAGTGTAAATCTAGATGACTATAACATACACGTCATTGCAAGTGTATTCAAACAATGGCTTCGAGATTTGCCC
AATCCTCTCATGACCTTTGAACTCTATGAGGAATTTCTTCGAGCTATGGGCCTTCAGGAGAGGAAGGAGACAATCCGTGGTGTATACTCT
GTGATTGATCAACTCTCCCGAACTCATCTCAATACACTGGAACGCCTCATCTTTCATCTAGTCAGGATTGCTCTGCAGGAAGACACTAAT
CGAATGTCTGCTAATGCTTTGGCCATTGTGTTTGCGCCCTGCATTCTCCGCTGCCCTGACACCACTGACCCACTACAAAGTGTACAGGAC
ATCAGTAAGACTACCACTTGTGTGGAACTGATTGTTGTGGAACAAATGAATAAATACAAGGCTCGTCTCAAAGATATCAGTAGCTTGGAA
TTTGCTGAGAATAAGGCAAAGACCAGGTTGTCACTGATTCGTAGATCAATGGGAAAGGGGCGTATTCGTCGAGGAAACTATCCAGGTCCA
TCGTCTCCTGTTGTAGTTCGGTTGCCTTCTGTGTCTGATGTCTCAGAGGAGACCTTGACTAGTGAGGCAGCCATGGAGACTGACATCACA
GAACAGCAGCAAGCAGCTATGCAGCAGGAGGAGAGAGTACTGACTGAGCAGATTGAGAACCTACAGAAGGAGAAGGAGGAGCTAACATTT
GAGATGCTTGTACTGGAACCCCGTGCCTCTGATGATGAAACCCTTGAGTCTGAGGCCTCCATTGGGACTGCTGATAGCTCAGAGAATTTG
AATATGGAGTCTGAATATGCTATCTCTGAGAAATCAGAAAGAAGCTTAGCCCTTAGCTCCCTGAAGACAGCTGGCAAGTCTGAACCTTCC
AGCAAGTTGCGAAAGCAACTTAAAAAGCAGCAAGACTCTTTAGATGTCGTGGACTCTTCGGTCTCCTCTTTATGTCTGTCTAACACGGCA
TCATCTCATGGGACCAGAAAACTATTTCAGATTTATTCCAAATCTCCATTCTACCGAGCTGCCTCAGGTAATGAGGCCCTGGGAATGGAA
GGACCATTGGGCCAGACCAAATTCCTGGAAGACAAGCCTCAGTTCATCAGCAGAGGAACCTTCAACCCGGAAAAGGGCAAACAAAAATTA
AAGAATGTGAAAAACTCACCTCAGAAAACCAAAGAGACCCCAGAGGGGACAGTCATGTCTGGCCGCAGAAAAACTGTGGACCCAGACTGC
ACCTCCAACCAACAGCTAGCACTCTTTGGAAATAATGAATTTATGGTCTGAACCGGCAGATGTGTGTCCCTCCGTGGCTACAGAGTGGTA
AACAAATCTCACCTTTGGGGCTGCGTTTCATCACCTCGTCCACAATAGTCAATCCTAATTGTGGTCCTGCCTCTTTTCTAAGCATATGGC
TAAGACTGTATGTGCTGAATTCCTGGGCCTCCTGCAGAAGCAGAAAGCCTGCTGGGGATGGTGCCAGCTGTGCCTTGGCTGTTGTATTTG
AATTGAGATTTTTACTATACAAAGCCACCTAGGGCCTGGGGATTTGGGTCAGTTGTAGTTGCCTCTCCCCCACCCTCTTTTCCCTTCCCA
AAGGTGGGTGTTGAACTAGGGGGGATATTGCTGTCCTGAGGGACCCTCTCATTTCTGACATTTGAAGAAAACGTATAAATCTTTCTTAAC
CGTGAAAGCAAAAGCCTTTGGGTTTATTTTGGGATAGTTAGGAGCTAGGGTAGAATATAATTTTTTTCCAAAAACTTACTTACAAACAAA
AAGCCTAATCCCTCTATTTTAAGATTTCTGAAAAAACACTCCATGTTATATTCTGGGGAAAGCAAAAACAAAAAAAAAAAACAAAAAAAA
AAAAACAAAAAAAAACCGTGATTGTTTCCATTAAGCCATCAGAGCGTGTCTCAGATATCTTGTTATACAGTGAAGAAGAGAATACCTATT
TTTTTTGATGATGTTTGATGTCATAGTAATCAGTGCTGGTTTAACTCCTGTTTAGTTCCTGCCAAATACATTGCATGGGCTGAAGTGTCA
GTAGCCATACTGTTCTCATGTTTCTTGGTCCTAGGATCAGATTCTTCTACATTATTTTTTAGTTTCCCAGAGACATGGTGATCCCTAAAC
TTATGAAGGTTTCATCCTAAGCCATTCAGGCTTTTCTCTTTGTATAGATTAAACCGAAAACCGCATATGAGCCTGTTCATCTGCTGGTGG
ATTCCCACCACAGACTCAGACTCAAACAAACAAACAAATAATGTGACCGTTTAGTTAGTTTCCAAAAACATTCACATACAATATTGCATG
AATAAGTAAGTAAGTGTTACAGAAAGCTGCCAAAAAATAAAAAGGTTTTTAATATGACCTATCTAACTAACTAACTTTTATCTTCCTTTT
CTCAGACTATCAGTATTAAATAGATGGAAAAAAATCAAGGACTACTTGAAGCTATTTTTGTTAATATTCTGGTTACTGAAGTTTATTGTA
AATATGTATGTATAGTAGGCATATTTCTTTTTAACCTTGTGCTTCCCTCCTTCCCATGGAATTTCTTCCCACAGATGAGGGGCCACTGGA
CAGGGGGATGAGAGCCATTCGTCCCTGGGTTGAGGGAATTAGTAAGACATCATTTTCACCACTGGGTGGTCTTCATACACATGAGTTATA
ATAGCATTTTAAGTATCTTAGCATTTGTGGGATTAGAAATCTGTTTTTGCTATTTATAATATATAAAAAATGAAACATGATAGCCTTTCT
TGAGATAAGTATGTGAAATGTTTATTTTTAAAGTTACTAAATGCATCTTGTCTTGCTACTACATGCACTGCTCTGAAAAAGAGCCTTTAC
CATCTATAACCTGTATTTTGGGTATTCTTCCTTTTCATACTTCTTTGAAGTTGTGGAAATATTAAGTCTTTTGTTAAGGCAGAGTCTCTC
TCTCCTGTTACACAACACTGAACCTCACGCCACTGCCTCAGTGGTTATTGGCCAGCCCCAGAGGTTAGACTTGGAGCATAATTCTGAGTG
GCAGCTAAAGGTAGCAGGAGTCTTACCTCTCCCTACTTTGGGTTCAGAATTGAGCCAGAGAAAGGAAGCCATTAAAATCTCCAGAATAAT
GATAGTTAATGAGCAAATGTTATGCTTTATATCCCACAGACATCTGCCACCTTGTTCATCTTGTCCTGAGGAGTAATAAATAATGTTAAG
CTTTTAAAAATCTGAATTTCAGAGAATCTCCTAGAGGATAGAGGAAAACCCCTCAGCATGGTGTGTTAGAGTGGGATTGCTGGTTCCTCA
GCCCCGTGCCAGGTTGCACAGTCTGTGTTTCAGTGTTCTTGGGAGAGTAGTGTACTGCTGGGCATTAATTGTTACTCTGCACTTGCTCCA
GAATGTTGGTTAAATCCTGTATGAAAAAAAGAGATTGCCCTTATGGAATAATTTCCTGTGGCCCAGAGGAATGGCCAGAAGAACATATGT
TGGCACATGTTCTTCCTTCTAAATCTTTGTGGGGCTTTTTTGGCAAAATAAGTTTTTTGGCAGTTAAAAAACGACTGATGTAGGTCACTT
TAAAGGAACTAGGTGATGGATGTTAAGAGACTTTATAATTTTTCTCAGGGACCTGAAACTCCAGTTTGGATAAAATTCAATTAAAAAAAC
TTGTTTTTTCAGTTGCTAGATTTGTGGATTTCTAGTAATTTAATCTGCCAGGATTGGGGTGGGTGGGTGAGGAGGAGAGAGCCACAAAAT
GATAAGAGTGGAGAGCAGTGTGGGGCCCTCCCTTTGAGGGAAAGCCGTTGTTTACATAGGGTAGTAGGCCTTGTTGGCCTGATCAAGAGA
TGAAGCCATAACTCTTAAAAACCTTCAGAACCAAACGCTGTGTCTGCATCCATCTGTTCTCACTGGCCCTCTGCATGGTAAAGTTATGTC
ACCACAAAGTGATGCCGCATTACAATCACTTATGAAACTGTTAGCCCTTAATATGCATCACATTTGTGGTTCCATAGTGCTTCTCCTTTG
CTTGTTTGATCTCTGCATGGCAGCAGTGGGGCAGCTCCACATTTGGAGCCCATACTCCAAAATGCAGAGCACTCTTCTCACAGCACACAT
TCCCAGCCCCAAACAAAACCTGAATTTTCAACTCTGCCCATTAAAGTGAATGTATCCCTGTAATTTAGTATGTACTTATTATGGAAAATG
TAACAAAAGCAGAGAAGTGTGATTTCATTCTGTATCACAAATTGAAGCAAATCAACAGCAAATACAGCAGGATTCAGGGAGGCTTAGTTT
ACAACGTACTTTGTACCTCCTGCCATTTAAATTATTTTGCCACTCTGGGCTTCTGAAAACACAAAGGGAGATACAGCCCTCCAACTATGA
GCCTTGCAGAGAGAGACAAAAGGGCCAGAGGTCCTGGGATGGAATACTAGAGCCCCCACCTTCTCATGCTTTGGAAACCTGCCAGAGCAC
TTACCCTGCTGGAAGATTAATGAAGACTCCATTCTGTGTTTCATAACAGTAGCGTTGTTTTCTCCATCAAAAACAGAGGGTCACAGAAAT
GTGCTGAAAAGATGTGGTCCAGCAAGGTTCTGTAGTCCCACCTCAGTGCCTGTGGGCTGTGTTTTTCACTGTAACAAGCACTTTGGTAAA
CTAGAAAGAAGAAAGGATTCTCAGGATGTGTTCAAAGCTAAGAGAGTTTTCATTTTAAAAAGAAACATACATACTCACTCCATGGCTTTC
CTCATCCTCCTCTCTTTTTTCTTCTTGGTGGGAAGCTGGATGCGGGGCATGCATCATTCTGTATGGACAAATGTGTTATGTCCACCCATA
CTCTTGTGACAACTCCCCAGCACTGTCCTGCAATACCATGCTGGCCTTGGTAGTAAAACTCCTTGGTATCTGTGAGAGTCCTCTTTTTCT
ATGCCCTAGACTACTTTTAACCACTTTTCTCTGGAATGACTCCCACATTTGATTGGGTATTGAAAGGGTAACAGCAAAATGATGATTGTG
GAGATGGATCTATTAGGTCTCATGTTGGTCCCCTGGTTGAAACTATTTTCAAAAAAGCCCCAACAATGGGCCTGTCACCTTGCTAGTCAT
CCATTCTTAATGCCTATTTATCAGCCCTCTGAGGTCATATAAAAGTTGCACCTTTTGAACCAAGTATTTGTATTTACTATGGGAAAGGTG
TGGACTACAGATTCGTATTATATTATTTTAATGGATTTTAAGTAATTTATAAGTATGCTGAGTGTAAATTTTTTTTAAAAACTGTATTAT
AAAAGGACATATCCTGTGAAATATAACATTTTACTGTTTAATAGAATAATTCTATAAGAAGAATGATTTATCTCACCCACGGAACTGATT
ACATTCCGGATGCAATCAATAGGCACTTTGTAATTTCCTTTTTGTTTTTTTTTCTTTGCTGGGGGGTTGAGGGGTAACAAGATACCATCT
GTATAAAGTGCAGTTTGTGTCACTCAAAATATGCACTGTATGGCTACACAAAAGCAGCTTGATGAACAAATCACCCCATGGCTCATTAAA

>62842_62842_1_PARP6-MYO9A_PARP6_chr15_72545778_ENST00000287196_MYO9A_chr15_72260466_ENST00000356056_length(amino acids)=2353AA_BP=1
MDIKGQFWNDDDSEGDNESEEFLYGVQGSCAADLYRHPQLDADIEAVKEIYSENSVSIREYGTIDDVDIDLHINISFLDEEVSTAWKVLR
TEPIVLRLRFSLSQYLDGPEPSIEVFQPSNKEGFGLGLQLKKILGMFTSQQWKHLSNDFLKTQQEKRHSWFKASGTIKKFRAGLSIFSPI
PKSPSFPIIQDSMLKGKLGVPELRVGRLMNRSISCTMKNPKVEVFGYPPSPQAGLLCPQHVGLPPPARTSPLVSGHCKNIPTLEYGFLVQ
IMKYAEQRIPTLNEYCVVCDEQHVFQNGSMLKPAVCTRELCVFSFYTLGVMSGAAEEVATGAEVVDLLVAMCRAALESPRKSIIFEPYPS
VVDPTDPKTLAFNPKKKNYERLQKALDSVMSIREMTQGSYLEIKKQMDKLDPLAHPLLQCFPQATNQTLLDKFKHQHEDNSYIEFPAVME
PAFIIKHYAGKVKYGVKDFREKNTDHMRPDIVALLRSSKNAFISGMIGIDPVAVFRWAILRAFFRAMVAFREAGKRNIHRKTGHDDTAPC
AILKSMDSFSFLQHPVHQRSLEILQRCKEEKYSITRKNPRTPLSDLQGMNALNEKNQHDTFDIAWNGRTGIRQSRLSSGTSLLDKDGIFA
NSTSSKLLERAHGILTRNKNFKSKPALPKHLLEVNSLKHLTRLTLQDRITKSLLHLHKKKKPPSISAQFQASLSKLMETLGQAEPYFVKC
IRSNAEKLPLRFSDVLVLRQLRYTGMLETVRIRQSGYSSKYSFQDFVSHFHVLLPRNIIPSKFNIQDFFRKINLNPDNYQVGKTMVFLKE
QERQHLQDLLHQEVLRRIILLQRWFRVLLCRQHFLHLRQASVIIQRFWRNYLNQKQVRDAAVQKDAFVMASAAALLQASWRAHLERQRYL
ELRAAAIVIQQKWRDYYRRRHMAAICIQARWKAYRESKRYQEQRKKIILLQSTCRGFRARQRFKALKEQRLRETKPEVGLVNIKGYGSLE
IQGSDPSGWEDCSFDNRIKAIEECKSVIESNRISRESSVDCLKESPNKQQERAQSQSGVDLQEDVLVRERPRSLEDLHQKKVGRAKRESR
RMRELEQAIFSLELLKVRSLGGISPSEDRRWSTELVPEGLQSPRGTPDSESSQGSLELLSYEESQKSKLESVISDEGDLQFPSPKISSSP
KFDSRDNALSASNETSSAEHLKDGTMKEMVVCSSESITCKPQLKDSFISNSLPTFFYIPQQDPLKTNSQLDTSIQRNKLLENEDTAGEAL
TLDINRETRRYHCSGKDQIVPSLNTESSNPVLKKLEKLNTEKEERQKQLQQQNEKEMMEQIRQQTDILEKERKAFKTIEKPRIGECLVAP
SSYQSKQRVERPSSLLSLNTSNKGELNVLGSLSLKDAALAQKDSSSAHLPPKDRPVTVFFERKGSPCQSSTVKELSKTDRMGTQLNVACK
LSNNRISKREHFRPTQSYSHNSDDLSREGNARPIFFTPKDNMSIPLVSKEALNSKNPQLHKEDEPAWKPVKLAGPGQRETSQRFSSVDEQ
AKLHKTMSQGEITKLAVRQKASDSDIRPQRAKMRFWAKGKQGEKKTTRVKPTTQSEVSPLFAGTDVIPAHQFPDELAAYHPTPPLSPELP
GSCRKEFKENKEPSPKAKRKRSVKISNVALDSMHWQNDSVQIIASVSDLKSMDEFLLKKVNDLDNEDSKKDTLVDVVFKKALKEFRQNIF
SFYSSALAMDDGKSIRYKDLYALFEQILEKTMRLEQRDSLGESPVRVWVNTFKVFLDEYMNEFKTSDCTATKVPKTERKKRRKKETDLVE
EHNGHIFKATQYSIPTYCEYCSSLIWIMDRASVCKLCKYACHKKCCLKTTAKCSKKYDPELSSRQFGVELSRLTSEDRTVPLVVEKLINY
IEMHGLYTEGIYRKSGSTNKIKELRQGLDTDAESVNLDDYNIHVIASVFKQWLRDLPNPLMTFELYEEFLRAMGLQERKETIRGVYSVID
QLSRTHLNTLERLIFHLVRIALQEDTNRMSANALAIVFAPCILRCPDTTDPLQSVQDISKTTTCVELIVVEQMNKYKARLKDISSLEFAE
NKAKTRLSLIRRSMGKGRIRRGNYPGPSSPVVVRLPSVSDVSEETLTSEAAMETDITEQQQAAMQQEERVLTEQIENLQKEKEELTFEML
VLEPRASDDETLESEASIGTADSSENLNMESEYAISEKSERSLALSSLKTAGKSEPSSKLRKQLKKQQDSLDVVDSSVSSLCLSNTASSH
GTRKLFQIYSKSPFYRAASGNEALGMEGPLGQTKFLEDKPQFISRGTFNPEKGKQKLKNVKNSPQKTKETPEGTVMSGRRKTVDPDCTSN

--------------------------------------------------------------
>62842_62842_2_PARP6-MYO9A_PARP6_chr15_72545778_ENST00000287196_MYO9A_chr15_72260466_ENST00000424560_length(transcript)=8286nt_BP=1718nt
CAACAGAAACCAAGCAGCAACAGCCCTTGGAAAGAGGCTAAATTTTTCTTGACTTCTGCAGCAACAAAGACCGTGAAAAGTTGGCACTTC
TGGCCTAACGCTGCCGTCATCCTACCCCTCACCCCAGGGCAACCCAGGCTGGACATTTAGTGCCTCCCTCTTTATTCCTCTGTGATCATC
CAGATCAGCACTTGACTGTTTATTTTCAAATCTCACGAACCTCACCCCAAGATCTTCACATTCTGGATCTCAGCTGCTCTTGAAGGACAG
TGACTTGTTACCACCGCAACAGCAGAGCCTGCCATCCCCAACAGATCACCAGTTGTCCCTGACATCGTGCCCTACCTTGTCTCCCTTTGT
GGTCTCCTAAATGCCCATCTCGTTGGCCTTGGTTCGGCTAGTGGTATGGAGGGGTGCTGCCTAGCACTGACCTGAGAGTGTGTGTGACCC
ACTGACCCAATGGACATCAAAGGCCAGTTCTGGAATGATGACGACTCGGAGGGAGATAATGAATCAGAGGAATTTCTCTATGGCGTTCAG
GGGAGCTGTGCAGCTGACCTGTATCGACACCCACAGCTTGATGCAGACATTGAAGCCGTGAAGGAGATCTACAGTGAGAACTCTGTATCC
ATCAGAGAATATGGAACTATCGATGACGTGGACATTGACCTCCACATCAACATCAGCTTCCTCGATGAGGAAGTCTCTACAGCCTGGAAG
GTCCTCCGGACAGAACCTATTGTGTTGAGGCTGCGATTTTCTCTCTCCCAGTACCTAGATGGACCAGAACCATCCATTGAGGTTTTCCAG
CCATCAAATAAGGAAGGATTTGGGCTGGGTCTTCAGTTGAAAAAGATCCTGGGTATGTTTACATCCCAACAATGGAAACATCTGAGCAAT
GATTTCTTGAAGACCCAGCAGGAGAAGAGGCACAGTTGGTTCAAGGCAAGTGGTACCATCAAGAAGTTCCGAGCTGGCCTCAGCATCTTT
TCACCCATCCCCAAGTCTCCCAGTTTCCCTATCATACAGGACTCCATGCTGAAAGGCAAACTAGGTGTACCAGAGCTTCGGGTTGGGCGC
CTCATGAACCGTTCCATCTCCTGTACCATGAAGAACCCCAAAGTGGAAGTGTTTGGCTACCCTCCCAGCCCCCAGGCAGGTCTCCTGTGC
CCTCAGCACGTGGGCCTCCCTCCCCCAGCACGGACCTCTCCTTTGGTCAGTGGTCACTGCAAGAACATTCCCACTCTGGAGTATGGATTC
CTCGTTCAGATCATGAAGTATGCAGAACAGAGGATTCCAACATTGAATGAGTACTGTGTGGTGTGTGATGAGCAGCATGTCTTCCAAAAT
GGATCTATGCTGAAGCCAGCTGTCTGTACTCGTGAACTATGCGTTTTCTCCTTCTACACACTGGGCGTCATGTCTGGAGCTGCAGAGGAG
GTGGCCACTGGAGCAGAGGTGGTGGATCTGCTGGTGGCCATGTGTAGGGCAGCTTTAGAGTCCCCTAGAAAGAGCATCATCTTTGAGCCT
TATCCCTCTGTGGTGGACCCCACTGATCCCAAGACTCTGGCCTTTAACCCTAAGAAGAAGAATTATGAGCGGCTTCAGAAAGCTCTGGAT
AGTGTGATGTCTATTCGGGAGATGACCCAGGGCTCATATTTGGAAATCAAGAAACAGATGGACAAGTTGGATCCCCTGGCCCATCCTCTC
CTGCAGTGCTTTCCACAGGCTACAAATCAAACATTGCTAGACAAGTTTAAGCATCAACATGAAGATAATTCTTACATCGAATTTCCAGCC
GTGATGGAGCCTGCTTTCATTATAAAACATTATGCTGGAAAAGTAAAATATGGGGTAAAGGATTTCCGGGAAAAAAATACAGATCATATG
CGCCCAGACATTGTAGCTCTTCTGAGAAGCAGCAAGAATGCATTTATCTCTGGGATGATTGGAATTGATCCTGTAGCTGTTTTCCGATGG
GCAATTCTCCGAGCTTTTTTCAGAGCCATGGTTGCTTTCAGGGAAGCTGGGAAAAGAAACATTCACAGAAAAACTGGACATGATGATACA
GCGCCATGTGCAATTTTGAAAAGTATGGATAGTTTTAGCTTTCTCCAACACCCAGTCCACCAGAGGAGCTTAGAGATTCTGCAGAGATGC
AAGGAAGAGAAGTACAGTATAACCCGGAAAAATCCCAGAACACCTCTTTCTGATCTCCAGGGCATGAATGCTCTAAATGAAAAAAACCAA
CATGATACATTTGATATTGCCTGGAATGGCAGAACTGGGATTCGCCAGAGCAGACTATCAAGTGGCACCTCCTTGCTTGATAAAGATGGA
ATATTTGCTAATTCAACTAGCAGCAAACTCCTGGAGAGAGCCCATGGAATTCTCACGAGAAACAAAAATTTCAAATCCAAGCCTGCCCTT
CCAAAGCACTTGCTAGAAGTAAATTCTTTAAAGCACCTGACAAGACTGACACTACAAGATCGCATTACCAAGTCTCTTCTTCATTTACAC
AAGAAGAAAAAACCTCCCAGCATCAGTGCCCAGTTTCAGGCATCATTAAGCAAGCTAATGGAAACACTTGGTCAAGCAGAACCATATTTT
GTAAAATGCATTCGCTCTAATGCTGAAAAGCTGCCCTTAAGGTTCAGTGATGTCTTGGTACTTAGACAGCTTCGATACACCGGGATGCTG
GAAACAGTTCGAATTCGCCAATCAGGATACAGCTCCAAATATTCTTTCCAGGATTTTGTGAGCCACTTCCATGTACTTCTTCCCCGAAAT
ATTATTCCATCCAAATTTAACATTCAGGATTTCTTCAGGAAAATAAATCTTAATCCAGATAATTATCAAGTTGGAAAAACCATGGTCTTT
CTAAAGGAGCAGGAACGACAGCACTTACAAGATCTGCTTCACCAAGAGGTGCTCCGCAGAATCATATTGTTGCAGCGATGGTTCAGGGTC
TTGCTGTGTAGGCAGCATTTCCTCCATCTGAGACAAGCATCTGTTATTATCCAGAGATTCTGGAGGAATTACCTAAATCAGAAGCAAGTC
AGAGATGCAGCTGTGCAGAAGGATGCTTTTGTTATGGCTAGTGCAGCTGCTCTTCTCCAAGCTTCCTGGCGTGCTCACTTAGAGAGGCAG
CGGTACTTGGAGTTACGGGCTGCAGCCATCGTTATCCAGCAGAAATGGAGAGATTACTATAGGCGCAGGCACATGGCTGCTATTTGCATA
CAAGCAAGATGGAAAGCCTACAGGGAAAGTAAAAGGTACCAAGAACAAAGGAAAAAAATTATCCTTTTGCAATCAACATGTAGAGGATTC
AGAGCAAGACAAAGATTTAAAGCTTTAAAAGAACAAAGGCTAAGAGAAACAAAGCCAGAAGTTGGATTGGTGAATATTAAGGGATATGGA
TCTCTGGAAATTCAGGGTTCAGACCCTTCAGGATGGGAGGATTGTTCTTTTGACAACAGAATAAAAGCCATAGAGGAATGTAAATCTGTA
ATAGAGAGTAATCGAATTAGCCGTGAAAGTTCAGTGGACTGCTTGAAGGAGTCACCAAACAAGCAGCAGGAGAGAGCCCAAAGCCAGAGT
GGTGTGGACTTGCAGGAAGATGTGCTTGTAAGAGAGAGACCCAGATCCTTGGAGGATCTCCATCAGAAAAAAGTAGGCCGGGCTAAGAGA
GAAAGTAGGAGAATGAGAGAACTAGAGCAAGCTATATTTAGCTTAGAATTGCTGAAAGTTCGTTCTCTTGGTGGTATTTCTCCTTCAGAG
GATCGCAGATGGTCTACAGAATTGGTGCCTGAAGGCCTTCAGTCTCCACGGGGTACACCTGATAGTGAGAGCTCTCAAGGAAGCTTGGAA
CTTCTGAGCTATGAGGAAAGCCAAAAGAGCAAACTAGAGTCTGTCATTTCAGATGAAGGAGACTTGCAGTTTCCATCACCTAAGATATCC
AGCAGTCCAAAATTTGATTCACGGGACAATGCCCTCAGTGCCTCAAATGAGACTAGCAGTGCAGAGCATTTGAAGGATGGAACTATGAAG
GAAATGGTGGTCTGCAGTTCTGAGTCTATTACCTGTAAACCACAGCTGAAAGACTCCTTCATTTCAAATAGTCTACCTACTTTTTTTTAT
ATCCCCCAACAAGACCCACTGAAAACAAATTCCCAACTAGACACAAGTATCCAAAGAAACAAACTATTGGAAAATGAAGACACAGCGGGG
GAAGCTCTTACTTTGGATATCAACAGGGAAACTAGAAGGTATCACTGCTCAGGAAAAGATCAGATTGTTCCTTCTTTGAATACAGAGTCT
TCTAATCCTGTGCTTAAGAAGTTAGAAAAGCTAAACACTGAGAAGGAAGAAAGGCAAAAACAGTTGCAGCAACAGAATGAAAAAGAGATG
ATGGAACAGATTCGCCAGCAAACAGATATTTTAGAGAAGGAGCGCAAAGCCTTCAAGACAATTGAAAAGCCAAGAATTGGAGAGTGTTTG
GTGGCACCATCTTCCTATCAGTCAAAGCAAAGAGTAGAGAGGCCATCCTCTCTCCTCAGCTTAAATACCTCAAATAAGGGAGAACTTAAT
GTACTGGGGTCCCTATCATTAAAAGATGCAGCTCTTGCCCAAAAAGACAGTTCCTCTGCTCACTTACCCCCAAAGGACCGACCTGTCACC
GTGTTCTTTGAAAGAAAAGGAAGTCCATGCCAATCTAGTACTGTCAAGGAATTATCCAAGACAGACAGAATGGGCACCCAGCTGAATGTA
GCCTGTAAACTCTCAAATAATCGCATTTCAAAAAGAGAACACTTTAGGCCAACTCAGTCTTACAGCCACAATTCTGATGACCTTTCCAGA
GAGGGAAATGCTAGGCCCATTTTCTTCACTCCAAAGGACAATATGAGTATTCCCCTTGTCAGCAAAGAAGCCTTAAACAGTAAAAATCCT
CAACTCCATAAAGAAGATGAACCAGCATGGAAACCTGTGAAGTTAGCTGGGCCAGGCCAAAGAGAGGTTGCCAGACCGGCCCATAAAAAG
AAAGCTCGAATGGCGCGGACGCGCTCCGATTTCTTGACTAGAGGTACTTTTGCCGATGGGGAGGGGGATACAGAGGAAGATGATTACGAT
GACATTATTGAGCCCCTTCTCTCCCTTGACCAAGCTTCTCACTGTGAGCTAGGGCCTGCACCCAGCCTGGGTCAGGCCTCTCACAGTGAC
TCCGAAATGACATCACAGCGATTTTCGTCAGTTGATGAACAAGCAAAACTTCATAAGACTATGTCTCAAGGAGAGATTACCAAGTTGGCA
GTGAGACAGAAGGCTTCAGATTCAGATATAAGACCTCAGAGAGCTAAGATGAGATTCTGGGCCAAAGGGAAACAAGGGGAGAAGAAGACT
ACCAGAGTGAAACCTACTACCCAGTCAGAGGTTTCGCCACTCTTTGCAGGCACAGATGTGATTCCAGCTCATCAGTTTCCAGATGAATTA
GCTGCATATCACCCAACACCTCCTTTGAGCCCAGAACTGCCCGGCAGTTGCCGGAAGGAATTCAAAGAGAACAAAGAACCTTCTCCAAAG
GCTAAGCGCAAGCGAAGTGTGAAGATTAGCAACGTGGCTTTGGATTCTATGCATTGGCAAAATGACTCTGTCCAGATCATAGCAAGTGTC
AGTGATTTAAAAAGCATGGATGAATTTCTTCTGAAAAAGGTGAATGACCTAGATAATGAAGACAGCAAGAAGGATACACTAGTGGATGTT
GTATTTAAAAAAGCCCTGAAGGAATTTCGGCAGAATATCTTCAGCTTTTATTCATCTGCATTGGCGATGGATGATGGGAAAAGCATACGG
TATAAAGACCTCTATGCACTATTTGAACAGATTCTGGAAAAGACGATGAGGCTTGAGCAGCGTGATTCACTGGGTGAATCTCCAGTGAGA
GTTTGGGTCAACACTTTTAAAGTGTTTTTAGATGAATATATGAATGAATTCAAGACTTCAGATTGCACAGCCACAAAGGTGCCAAAAACA
GAAAGAAAGAAAAGAAGGAAAAAGGAAACTGATTTGGTGGAAGAACACAATGGTCACATCTTTAAAGCCACCCAATATAGCATCCCTACA
TACTGTGAATACTGTTCTTCTTTGATATGGATAATGGACCGAGCCTCTGTTTGCAAATTATGCAAGTATGCTTGCCATAAGAAGTGCTGT
CTGAAAACCACAGCCAAGTGCTCTAAAAAGTATGATCCAGAGCTGTCATCTCGACAATTTGGGGTTGAACTGTCCCGTTTGACCAGTGAA
GACCGAACTGTTCCTTTAGTAGTGGAAAAGCTCATAAACTACATTGAAATGCATGGACTGTATACAGAAGGTATTTATCGAAAGTCTGGT
TCGACTAATAAAATCAAGGAGCTTCGGCAGGGTCTAGATACAGATGCTGAGAGTGTAAATCTAGATGACTATAACATACACGTCATTGCA
AGTGTATTCAAACAATGGCTTCGAGATTTGCCCAATCCTCTCATGACCTTTGAACTCTATGAGGAATTTCTTCGAGCTATGGGCCTTCAG
GAGAGGAAGGAGACAATCCGTGGTGTATACTCTGTGATTGATCAACTCTCCCGAACTCATCTCAATACACTGGAACGCCTCATCTTTCAT
CTAGTCAGGATTGCTCTGCAGGAAGACACTAATCGAATGTCTGCTAATGCTTTGGCCATTGTGTTTGCGCCCTGCATTCTCCGCTGCCCT
GACACCACTGACCCACTACAAAGTGTACAGGACATCAGTAAGACTACCACTTGTGTGGAACTGATTGTTGTGGAACAAATGAATAAATAC
AAGGCTCGTCTCAAAGATATCAGTAGCTTGGAATTTGCTGAGAATAAGGCAAAGACCAGGTTGTCACTGATTCGTAGATCAATGGGAAAG
GGGCGTATTCGTCGAGGAAACTATCCAGGTCCATCGTCTCCTGTTGTAGTTCGGTTGCCTTCTGTGTCTGATGTCTCAGAGGAGACCTTG
ACTAGTGAGGCAGCCATGGAGACTGACATCACAGAACAGCAGCAAGCAGCTATGCAGCAGGAGGAGAGAGTACTGACTGAGCAGATTGAG
AACCTACAGAAGGAGAAGGAGGAGCTAACATTTGAGATGCTTGTACTGGAACCCCGTGCCTCTGATGATGAAACCCTTGAGTCTGAGGCC
TCCATTGGGACTGCTGATAGCTCAGAGAATTTGAATATGGAGTCTGAATATGCTATCTCTGAGAAATCAGAAAGAAGCTTAGCCCTTAGC
TCCCTGAAGACAGCTGGCAAGTCTGAACCTTCCAGCAAGTTGCGAAAGCAACTTAAAAAGCAGCAAGACTCTTTAGATGTCGTGGACTCT
TCGGTCTCCTCTTTATGTCTGTCTAACACGGCATCATCTCATGGGACCAGAAAACTATTTCAGATTTATTCCAAATCTCCATTCTACCGA
GCTGCCTCAGGTAATGAGGCCCTGGGAATGGAAGGACCATTGGGCCAGACCAAATTCCTGGAAGACAAGCCTCAGTTCATCAGCAGAGGA
ACCTTCAACCCGGAAAAGGGCAAACAAAAATTAAAGAATGTGAAAAACTCACCTCAGAAAACCAAAGAGACCCCAGAGGGGACAGTCATG
TCTGGCCGCAGAAAAACTGTGGACCCAGACTGCACCTCCAACCAACAGCTAGCACTCTTTGGAAATAATGAATTTATGGTCTGAACCGGC
AGATGTGTGTCCCTCCGTGGCTACAGAGTGGTAAACAAATCTCACCTTTGGGGCTGCGTTTCATCACCTCGTCCACAATAGTCAATCCTA
ATTGTGGTCCTGCCTCTTTTCTAAGCATATGGCTAAGACTGTATGTGCTGAATTCCTGGGCCTCCTGCAGAAGCAGAAAGCCTGCTGGGG
ATGGTGCCAGCTGTGCCTTGGCTGTTGTATTTGAATTGAGATTTTTACTATACAAAGCCACCTAGGGCCTGGGGATTTGGGTCAGTTGTA
GTTGCCTCTCCCCCACCCTCTTTTCCCTTCCCAAAGGTGGGTGTTGAACTAGGGGGGATATTGCTGTCCTGAGGGACCCTCTCATTTCTG
ACATTTGAAGAAAACGTATAAATCTTTCTTAACCGTGAAAGCAAAAGCCTTTGGGTTTATTTTGGGATAGTTAGGAGCTAGGGTAGAATA
TAATTTTTTTCCAAAAACTTACTTACAAACAAAAAGCCTAATCCCTCTATTTTAAGATTTCTGAAAAAACACTCCATGTTATATTCTGGG

>62842_62842_2_PARP6-MYO9A_PARP6_chr15_72545778_ENST00000287196_MYO9A_chr15_72260466_ENST00000424560_length(amino acids)=2424AA_BP=1
MDIKGQFWNDDDSEGDNESEEFLYGVQGSCAADLYRHPQLDADIEAVKEIYSENSVSIREYGTIDDVDIDLHINISFLDEEVSTAWKVLR
TEPIVLRLRFSLSQYLDGPEPSIEVFQPSNKEGFGLGLQLKKILGMFTSQQWKHLSNDFLKTQQEKRHSWFKASGTIKKFRAGLSIFSPI
PKSPSFPIIQDSMLKGKLGVPELRVGRLMNRSISCTMKNPKVEVFGYPPSPQAGLLCPQHVGLPPPARTSPLVSGHCKNIPTLEYGFLVQ
IMKYAEQRIPTLNEYCVVCDEQHVFQNGSMLKPAVCTRELCVFSFYTLGVMSGAAEEVATGAEVVDLLVAMCRAALESPRKSIIFEPYPS
VVDPTDPKTLAFNPKKKNYERLQKALDSVMSIREMTQGSYLEIKKQMDKLDPLAHPLLQCFPQATNQTLLDKFKHQHEDNSYIEFPAVME
PAFIIKHYAGKVKYGVKDFREKNTDHMRPDIVALLRSSKNAFISGMIGIDPVAVFRWAILRAFFRAMVAFREAGKRNIHRKTGHDDTAPC
AILKSMDSFSFLQHPVHQRSLEILQRCKEEKYSITRKNPRTPLSDLQGMNALNEKNQHDTFDIAWNGRTGIRQSRLSSGTSLLDKDGIFA
NSTSSKLLERAHGILTRNKNFKSKPALPKHLLEVNSLKHLTRLTLQDRITKSLLHLHKKKKPPSISAQFQASLSKLMETLGQAEPYFVKC
IRSNAEKLPLRFSDVLVLRQLRYTGMLETVRIRQSGYSSKYSFQDFVSHFHVLLPRNIIPSKFNIQDFFRKINLNPDNYQVGKTMVFLKE
QERQHLQDLLHQEVLRRIILLQRWFRVLLCRQHFLHLRQASVIIQRFWRNYLNQKQVRDAAVQKDAFVMASAAALLQASWRAHLERQRYL
ELRAAAIVIQQKWRDYYRRRHMAAICIQARWKAYRESKRYQEQRKKIILLQSTCRGFRARQRFKALKEQRLRETKPEVGLVNIKGYGSLE
IQGSDPSGWEDCSFDNRIKAIEECKSVIESNRISRESSVDCLKESPNKQQERAQSQSGVDLQEDVLVRERPRSLEDLHQKKVGRAKRESR
RMRELEQAIFSLELLKVRSLGGISPSEDRRWSTELVPEGLQSPRGTPDSESSQGSLELLSYEESQKSKLESVISDEGDLQFPSPKISSSP
KFDSRDNALSASNETSSAEHLKDGTMKEMVVCSSESITCKPQLKDSFISNSLPTFFYIPQQDPLKTNSQLDTSIQRNKLLENEDTAGEAL
TLDINRETRRYHCSGKDQIVPSLNTESSNPVLKKLEKLNTEKEERQKQLQQQNEKEMMEQIRQQTDILEKERKAFKTIEKPRIGECLVAP
SSYQSKQRVERPSSLLSLNTSNKGELNVLGSLSLKDAALAQKDSSSAHLPPKDRPVTVFFERKGSPCQSSTVKELSKTDRMGTQLNVACK
LSNNRISKREHFRPTQSYSHNSDDLSREGNARPIFFTPKDNMSIPLVSKEALNSKNPQLHKEDEPAWKPVKLAGPGQREVARPAHKKKAR
MARTRSDFLTRGTFADGEGDTEEDDYDDIIEPLLSLDQASHCELGPAPSLGQASHSDSEMTSQRFSSVDEQAKLHKTMSQGEITKLAVRQ
KASDSDIRPQRAKMRFWAKGKQGEKKTTRVKPTTQSEVSPLFAGTDVIPAHQFPDELAAYHPTPPLSPELPGSCRKEFKENKEPSPKAKR
KRSVKISNVALDSMHWQNDSVQIIASVSDLKSMDEFLLKKVNDLDNEDSKKDTLVDVVFKKALKEFRQNIFSFYSSALAMDDGKSIRYKD
LYALFEQILEKTMRLEQRDSLGESPVRVWVNTFKVFLDEYMNEFKTSDCTATKVPKTERKKRRKKETDLVEEHNGHIFKATQYSIPTYCE
YCSSLIWIMDRASVCKLCKYACHKKCCLKTTAKCSKKYDPELSSRQFGVELSRLTSEDRTVPLVVEKLINYIEMHGLYTEGIYRKSGSTN
KIKELRQGLDTDAESVNLDDYNIHVIASVFKQWLRDLPNPLMTFELYEEFLRAMGLQERKETIRGVYSVIDQLSRTHLNTLERLIFHLVR
IALQEDTNRMSANALAIVFAPCILRCPDTTDPLQSVQDISKTTTCVELIVVEQMNKYKARLKDISSLEFAENKAKTRLSLIRRSMGKGRI
RRGNYPGPSSPVVVRLPSVSDVSEETLTSEAAMETDITEQQQAAMQQEERVLTEQIENLQKEKEELTFEMLVLEPRASDDETLESEASIG
TADSSENLNMESEYAISEKSERSLALSSLKTAGKSEPSSKLRKQLKKQQDSLDVVDSSVSSLCLSNTASSHGTRKLFQIYSKSPFYRAAS

--------------------------------------------------------------
>62842_62842_3_PARP6-MYO9A_PARP6_chr15_72545778_ENST00000287196_MYO9A_chr15_72260466_ENST00000444904_length(transcript)=8073nt_BP=1718nt
CAACAGAAACCAAGCAGCAACAGCCCTTGGAAAGAGGCTAAATTTTTCTTGACTTCTGCAGCAACAAAGACCGTGAAAAGTTGGCACTTC
TGGCCTAACGCTGCCGTCATCCTACCCCTCACCCCAGGGCAACCCAGGCTGGACATTTAGTGCCTCCCTCTTTATTCCTCTGTGATCATC
CAGATCAGCACTTGACTGTTTATTTTCAAATCTCACGAACCTCACCCCAAGATCTTCACATTCTGGATCTCAGCTGCTCTTGAAGGACAG
TGACTTGTTACCACCGCAACAGCAGAGCCTGCCATCCCCAACAGATCACCAGTTGTCCCTGACATCGTGCCCTACCTTGTCTCCCTTTGT
GGTCTCCTAAATGCCCATCTCGTTGGCCTTGGTTCGGCTAGTGGTATGGAGGGGTGCTGCCTAGCACTGACCTGAGAGTGTGTGTGACCC
ACTGACCCAATGGACATCAAAGGCCAGTTCTGGAATGATGACGACTCGGAGGGAGATAATGAATCAGAGGAATTTCTCTATGGCGTTCAG
GGGAGCTGTGCAGCTGACCTGTATCGACACCCACAGCTTGATGCAGACATTGAAGCCGTGAAGGAGATCTACAGTGAGAACTCTGTATCC
ATCAGAGAATATGGAACTATCGATGACGTGGACATTGACCTCCACATCAACATCAGCTTCCTCGATGAGGAAGTCTCTACAGCCTGGAAG
GTCCTCCGGACAGAACCTATTGTGTTGAGGCTGCGATTTTCTCTCTCCCAGTACCTAGATGGACCAGAACCATCCATTGAGGTTTTCCAG
CCATCAAATAAGGAAGGATTTGGGCTGGGTCTTCAGTTGAAAAAGATCCTGGGTATGTTTACATCCCAACAATGGAAACATCTGAGCAAT
GATTTCTTGAAGACCCAGCAGGAGAAGAGGCACAGTTGGTTCAAGGCAAGTGGTACCATCAAGAAGTTCCGAGCTGGCCTCAGCATCTTT
TCACCCATCCCCAAGTCTCCCAGTTTCCCTATCATACAGGACTCCATGCTGAAAGGCAAACTAGGTGTACCAGAGCTTCGGGTTGGGCGC
CTCATGAACCGTTCCATCTCCTGTACCATGAAGAACCCCAAAGTGGAAGTGTTTGGCTACCCTCCCAGCCCCCAGGCAGGTCTCCTGTGC
CCTCAGCACGTGGGCCTCCCTCCCCCAGCACGGACCTCTCCTTTGGTCAGTGGTCACTGCAAGAACATTCCCACTCTGGAGTATGGATTC
CTCGTTCAGATCATGAAGTATGCAGAACAGAGGATTCCAACATTGAATGAGTACTGTGTGGTGTGTGATGAGCAGCATGTCTTCCAAAAT
GGATCTATGCTGAAGCCAGCTGTCTGTACTCGTGAACTATGCGTTTTCTCCTTCTACACACTGGGCGTCATGTCTGGAGCTGCAGAGGAG
GTGGCCACTGGAGCAGAGGTGGTGGATCTGCTGGTGGCCATGTGTAGGGCAGCTTTAGAGTCCCCTAGAAAGAGCATCATCTTTGAGCCT
TATCCCTCTGTGGTGGACCCCACTGATCCCAAGACTCTGGCCTTTAACCCTAAGAAGAAGAATTATGAGCGGCTTCAGAAAGCTCTGGAT
AGTGTGATGTCTATTCGGGAGATGACCCAGGGCTCATATTTGGAAATCAAGAAACAGATGGACAAGTTGGATCCCCTGGCCCATCCTCTC
CTGCAGTGCTTTCCACAGGCTACAAATCAAACATTGCTAGACAAGTTTAAGCATCAACATGAAGATAATTCTTACATCGAATTTCCAGCC
GTGATGGAGCCTGCTTTCATTATAAAACATTATGCTGGAAAAGTAAAATATGGGGTAAAGGATTTCCGGGAAAAAAATACAGATCATATG
CGCCCAGACATTGTAGCTCTTCTGAGAAGCAGCAAGAATGCATTTATCTCTGGGATGATTGGAATTGATCCTGTAGCTGTTTTCCGATGG
GCAATTCTCCGAGCTTTTTTCAGAGCCATGGTTGCTTTCAGGGAAGCTGGGAAAAGAAACATTCACAGAAAAACTGGACATGATGATACA
GCGCCATGTGCAATTTTGAAAAGTATGGATAGTTTTAGCTTTCTCCAACACCCAGTCCACCAGAGGAGCTTAGAGATTCTGCAGAGATGC
AAGGAAGAGAAGTACAGTATAACCCGGAAAAATCCCAGAACACCTCTTTCTGATCTCCAGGGCATGAATGCTCTAAATGAAAAAAACCAA
CATGATACATTTGATATTGCCTGGAATGGCAGAACTGGGATTCGCCAGAGCAGACTATCAAGTGGCACCTCCTTGCTTGATAAAGATGGA
ATATTTGCTAATTCAACTAGCAGCAAACTCCTGGAGAGAGCCCATGGAATTCTCACGAGAAACAAAAATTTCAAATCCAAGCCTGCCCTT
CCAAAGCACTTGCTAGAAGTAAATTCTTTAAAGCACCTGACAAGACTGACACTACAAGATCGCATTACCAAGTCTCTTCTTCATTTACAC
AAGAAGAAAAAACCTCCCAGCATCAGTGCCCAGTTTCAGGCATCATTAAGCAAGCTAATGGAAACACTTGGTCAAGCAGAACCATATTTT
GTAAAATGCATTCGCTCTAATGCTGAAAAGCTGCCCTTAAGGTTCAGTGATGTCTTGGTACTTAGACAGCTTCGATACACCGGGATGCTG
GAAACAGTTCGAATTCGCCAATCAGGATACAGCTCCAAATATTCTTTCCAGGATTTTGTGAGCCACTTCCATGTACTTCTTCCCCGAAAT
ATTATTCCATCCAAATTTAACATTCAGGATTTCTTCAGGAAAATAAATCTTAATCCAGATAATTATCAAGTTGGAAAAACCATGGTCTTT
CTAAAGGAGCAGGAACGACAGCACTTACAAGATCTGCTTCACCAAGAGGTGCTCCGCAGAATCATATTGTTGCAGCGATGGTTCAGGGTC
TTGCTGTGTAGGCAGCATTTCCTCCATCTGAGACAAGCATCTGTTATTATCCAGAGATTCTGGAGGAATTACCTAAATCAGAAGCAAGTC
AGAGATGCAGCTGTGCAGAAGGATGCTTTTGTTATGGCTAGTGCAGCTGCTCTTCTCCAAGCTTCCTGGCGTGCTCACTTAGAGAGGCAG
CGGTACTTGGAGTTACGGGCTGCAGCCATCGTTATCCAGCAGAAATGGAGAGATTACTATAGGCGCAGGCACATGGCTGCTATTTGCATA
CAAGCAAGATGGAAAGCCTACAGGGAAAGTAAAAGGTACCAAGAACAAAGGAAAAAAATTATCCTTTTGCAATCAACATGTAGAGGATTC
AGAGCAAGACAAAGATTTAAAGCTTTAAAAGAACAAAGGCTAAGAGAAACAAAGCCAGAAGTTGGATTGGTGAATATTAAGGGATATGGA
TCTCTGGAAATTCAGGGTTCAGACCCTTCAGGATGGGAGGATTGTTCTTTTGACAACAGAATAAAAGCCATAGAGGAATGTAAATCTGTA
ATAGAGAGTAATCGAATTAGCCGTGAAAGTTCAGTGGACTGCTTGAAGGAGTCACCAAACAAGCAGCAGGAGAGAGCCCAAAGCCAGAGT
GGTGTGGACTTGCAGGAAGATGTGCTTGTAAGAGAGAGACCCAGATCCTTGGAGGATCTCCATCAGAAAAAAGTAGGCCGGGCTAAGAGA
GAAAGTAGGAGAATGAGAGAACTAGAGCAAGCTATATTTAGCTTAGAATTGCTGAAAGTTCGTTCTCTTGGTGGTATTTCTCCTTCAGAG
GATCGCAGATGGTCTACAGAATTGGTGCCTGAAGGCCTTCAGTCTCCACGGGGTACACCTGATAGTGAGAGCTCTCAAGGAAGCTTGGAA
CTTCTGAGCTATGAGGAAAGCCAAAAGAGCAAACTAGAGTCTGTCATTTCAGATGAAGGAGACTTGCAGTTTCCATCACCTAAGATATCC
AGCAGTCCAAAATTTGATTCACGGGACAATGCCCTCAGTGCCTCAAATGAGACTAGCAGTGCAGAGCATTTGAAGGATGGAACTATGAAG
GAAATGGTGGTCTGCAGTTCTGAGTCTATTACCTGTAAACCACAGCTGAAAGACTCCTTCATTTCAAATAGTCTACCTACTTTTTTTTAT
ATCCCCCAACAAGACCCACTGAAAACAAATTCCCAACTAGACACAAGTATCCAAAGAAACAAACTATTGGAAAATGAAGACACAGCGGGG
GAAGCTCTTACTTTGGATATCAACAGGGAAACTAGAAGGTATCACTGCTCAGGAAAAGATCAGATTGTTCCTTCTTTGAATACAGAGTCT
TCTAATCCTGTGCTTAAGAAGTTAGAAAAGCTAAACACTGAGAAGGAAGAAAGGCAAAAACAGTTGCAGCAACAGAATGAAAAAGAGATG
ATGGAACAGATTCGCCAGCAAACAGATATTTTAGAGAAGGAGCGCAAAGCCTTCAAGACAATTGAAAAGCCAAGAATTGGAGAGTGTTTG
GTGGCACCATCTTCCTATCAGTCAAAGCAAAGAGTAGAGAGGCCATCCTCTCTCCTCAGCTTAAATACCTCAAATAAGGGAGAACTTAAT
GTACTGGGGTCCCTATCATTAAAAGATGCAGCTCTTGCCCAAAAAGACAGTTCCTCTGCTCACTTACCCCCAAAGGACCGACCTGTCACC
GTGTTCTTTGAAAGAAAAGGAAGTCCATGCCAATCTAGTACTGTCAAGGAATTATCCAAGACAGACAGAATGGGCACCCAGCTGAATGTA
GCCTGTAAACTCTCAAATAATCGCATTTCAAAAAGAGAACACTTTAGGCCAACTCAGTCTTACAGCCACAATTCTGATGACCTTTCCAGA
GAGGGAAATGCTAGGCCCATTTTCTTCACTCCAAAGGACAATATGAGTATTCCCCTTGTCAGCAAAGAAGCCTTAAACAGTAAAAATCCT
CAACTCCATAAAGAAGATGAACCAGCATGGAAACCTGTGAAGTTAGCTGGGCCAGGCCAAAGAGAGACATCACAGCGATTTTCGTCAGTT
GATGAACAAGCAAAACTTCATAAGACTATGTCTCAAGGAGAGATTACCAAGTTGGCAGTGAGACAGAAGGCTTCAGATTCAGATATAAGA
CCTCAGAGAGCTAAGATGAGATTCTGGGCCAAAGGGAAACAAGGGGAGAAGAAGACTACCAGAGTGAAACCTACTACCCAGTCAGAGGTT
TCGCCACTCTTTGCAGGCACAGATGTGATTCCAGCTCATCAGTTTCCAGATGAATTAGCTGCATATCACCCAACACCTCCTTTGAGCCCA
GAACTGCCCGGCAGTTGCCGGAAGGAATTCAAAGAGAACAAAGAACCTTCTCCAAAGGCTAAGCGCAAGCGAAGTGTGAAGATTAGCAAC
GTGGCTTTGGATTCTATGCATTGGCAAAATGACTCTGTCCAGATCATAGCAAGTGTCAGTGATTTAAAAAGCATGGATGAATTTCTTCTG
AAAAAGGTGAATGACCTAGATAATGAAGACAGCAAGAAGGATACACTAGTGGATGTTGTATTTAAAAAAGCCCTGAAGGAATTTCGGCAG
AATATCTTCAGCTTTTATTCATCTGCATTGGCGATGGATGATGGGAAAAGCATACGGTATAAAGACCTCTATGCACTATTTGAACAGATT
CTGGAAAAGACGATGAGGCTTGAGCAGCGTGATTCACTGGGTGAATCTCCAGTGAGAGTTTGGGTCAACACTTTTAAAGTGTTTTTAGAT
GAATATATGAATGAATTCAAGACTTCAGATTGCACAGCCACAAAGGTGCCAAAAACAGAAAGAAAGAAAAGAAGGAAAAAGGAAACTGAT
TTGGTGGAAGAACACAATGGTCACATCTTTAAAGCCACCCAATATAGCATCCCTACATACTGTGAATACTGTTCTTCTTTGATATGGATA
ATGGACCGAGCCTCTGTTTGCAAATTATGCAAGTATGCTTGCCATAAGAAGTGCTGTCTGAAAACCACAGCCAAGTGCTCTAAAAAGTAT
GATCCAGAGCTGTCATCTCGACAATTTGGGGTTGAACTGTCCCGTTTGACCAGTGAAGACCGAACTGTTCCTTTAGTAGTGGAAAAGCTC
ATAAACTACATTGAAATGCATGGACTGTATACAGAAGGTATTTATCGAAAGTCTGGTTCGACTAATAAAATCAAGGAGCTTCGGCAGGGT
CTAGATACAGATGCTGAGAGTGTAAATCTAGATGACTATAACATACACGTCATTGCAAGTGTATTCAAACAATGGCTTCGAGATTTGCCC
AATCCTCTCATGACCTTTGAACTCTATGAGGAATTTCTTCGAGCTATGGGCCTTCAGGAGAGGAAGGAGACAATCCGTGGTGTATACTCT
GTGATTGATCAACTCTCCCGAACTCATCTCAATACACTGGAACGCCTCATCTTTCATCTAGTCAGGATTGCTCTGCAGGAAGACACTAAT
CGAATGTCTGCTAATGCTTTGGCCATTGTGTTTGCGCCCTGCATTCTCCGCTGCCCTGACACCACTGACCCACTACAAAGTGTACAGGAC
ATCAGTAAGACTACCACTTGTGTGGAACTGATTGTTGTGGAACAAATGAATAAATACAAGGCTCGTCTCAAAGATATCAGTAGCTTGGAA
TTTGCTGAGAATAAGGCAAAGACCAGGTTGTCACTGATTCGTAGATCAATGGGAAAGGGGCGTATTCGTCGAGGAAACTATCCAGGTCCA
TCGTCTCCTGTTGTAGTTCGGTTGCCTTCTGTGTCTGATGTCTCAGAGGAGACCTTGACTAGTGAGGCAGCCATGGAGACTGACATCACA
GAACAGCAGCAAGCAGCTATGCAGCAGGAGGAGAGAGTACTGACTGAGCAGATTGAGAACCTACAGAAGGAGAAGGAGGAGCTAACATTT
GAGATGCTTGTACTGGAACCCCGTGCCTCTGATGATGAAACCCTTGAGTCTGAGGCCTCCATTGGGACTGCTGATAGCTCAGAGAATTTG
AATATGGAGTCTGAATATGCTATCTCTGAGAAATCAGAAAGAAGCTTAGCCCTTAGCTCCCTGAAGACAGCTGGCAAGTCTGAACCTTCC
AGCAAGTTGCGAAAGCAACTTAAAAAGCAGCAAGACTCTTTAGATGTCGTGGACTCTTCGGTCTCCTCTTTATGTCTGTCTAACACGGCA
TCATCTCATGGGACCAGAAAACTATTTCAGATTTATTCCAAATCTCCATTCTACCGAGCTGCCTCAGGTAATGAGGCCCTGGGAATGGAA
GGACCATTGGGCCAGACCAAATTCCTGGAAGACAAGCCTCAGTTCATCAGCAGAGGAACCTTCAACCCGGAAAAGGGCAAACAAAAATTA
AAGAATGTGAAAAACTCACCTCAGAAAACCAAAGAGACCCCAGAGGGGACAGTCATGTCTGGCCGCAGAAAAACTGTGGACCCAGACTGC
ACCTCCAACCAACAGCTAGCACTCTTTGGAAATAATGAATTTATGGTCTGAACCGGCAGATGTGTGTCCCTCCGTGGCTACAGAGTGGTA
AACAAATCTCACCTTTGGGGCTGCGTTTCATCACCTCGTCCACAATAGTCAATCCTAATTGTGGTCCTGCCTCTTTTCTAAGCATATGGC
TAAGACTGTATGTGCTGAATTCCTGGGCCTCCTGCAGAAGCAGAAAGCCTGCTGGGGATGGTGCCAGCTGTGCCTTGGCTGTTGTATTTG
AATTGAGATTTTTACTATACAAAGCCACCTAGGGCCTGGGGATTTGGGTCAGTTGTAGTTGCCTCTCCCCCACCCTCTTTTCCCTTCCCA
AAGGTGGGTGTTGAACTAGGGGGGATATTGCTGTCCTGAGGGACCCTCTCATTTCTGACATTTGAAGAAAACGTATAAATCTTTCTTAAC
CGTGAAAGCAAAAGCCTTTGGGTTTATTTTGGGATAGTTAGGAGCTAGGGTAGAATATAATTTTTTTCCAAAAACTTACTTACAAACAAA

>62842_62842_3_PARP6-MYO9A_PARP6_chr15_72545778_ENST00000287196_MYO9A_chr15_72260466_ENST00000444904_length(amino acids)=2353AA_BP=1
MDIKGQFWNDDDSEGDNESEEFLYGVQGSCAADLYRHPQLDADIEAVKEIYSENSVSIREYGTIDDVDIDLHINISFLDEEVSTAWKVLR
TEPIVLRLRFSLSQYLDGPEPSIEVFQPSNKEGFGLGLQLKKILGMFTSQQWKHLSNDFLKTQQEKRHSWFKASGTIKKFRAGLSIFSPI
PKSPSFPIIQDSMLKGKLGVPELRVGRLMNRSISCTMKNPKVEVFGYPPSPQAGLLCPQHVGLPPPARTSPLVSGHCKNIPTLEYGFLVQ
IMKYAEQRIPTLNEYCVVCDEQHVFQNGSMLKPAVCTRELCVFSFYTLGVMSGAAEEVATGAEVVDLLVAMCRAALESPRKSIIFEPYPS
VVDPTDPKTLAFNPKKKNYERLQKALDSVMSIREMTQGSYLEIKKQMDKLDPLAHPLLQCFPQATNQTLLDKFKHQHEDNSYIEFPAVME
PAFIIKHYAGKVKYGVKDFREKNTDHMRPDIVALLRSSKNAFISGMIGIDPVAVFRWAILRAFFRAMVAFREAGKRNIHRKTGHDDTAPC
AILKSMDSFSFLQHPVHQRSLEILQRCKEEKYSITRKNPRTPLSDLQGMNALNEKNQHDTFDIAWNGRTGIRQSRLSSGTSLLDKDGIFA
NSTSSKLLERAHGILTRNKNFKSKPALPKHLLEVNSLKHLTRLTLQDRITKSLLHLHKKKKPPSISAQFQASLSKLMETLGQAEPYFVKC
IRSNAEKLPLRFSDVLVLRQLRYTGMLETVRIRQSGYSSKYSFQDFVSHFHVLLPRNIIPSKFNIQDFFRKINLNPDNYQVGKTMVFLKE
QERQHLQDLLHQEVLRRIILLQRWFRVLLCRQHFLHLRQASVIIQRFWRNYLNQKQVRDAAVQKDAFVMASAAALLQASWRAHLERQRYL
ELRAAAIVIQQKWRDYYRRRHMAAICIQARWKAYRESKRYQEQRKKIILLQSTCRGFRARQRFKALKEQRLRETKPEVGLVNIKGYGSLE
IQGSDPSGWEDCSFDNRIKAIEECKSVIESNRISRESSVDCLKESPNKQQERAQSQSGVDLQEDVLVRERPRSLEDLHQKKVGRAKRESR
RMRELEQAIFSLELLKVRSLGGISPSEDRRWSTELVPEGLQSPRGTPDSESSQGSLELLSYEESQKSKLESVISDEGDLQFPSPKISSSP
KFDSRDNALSASNETSSAEHLKDGTMKEMVVCSSESITCKPQLKDSFISNSLPTFFYIPQQDPLKTNSQLDTSIQRNKLLENEDTAGEAL
TLDINRETRRYHCSGKDQIVPSLNTESSNPVLKKLEKLNTEKEERQKQLQQQNEKEMMEQIRQQTDILEKERKAFKTIEKPRIGECLVAP
SSYQSKQRVERPSSLLSLNTSNKGELNVLGSLSLKDAALAQKDSSSAHLPPKDRPVTVFFERKGSPCQSSTVKELSKTDRMGTQLNVACK
LSNNRISKREHFRPTQSYSHNSDDLSREGNARPIFFTPKDNMSIPLVSKEALNSKNPQLHKEDEPAWKPVKLAGPGQRETSQRFSSVDEQ
AKLHKTMSQGEITKLAVRQKASDSDIRPQRAKMRFWAKGKQGEKKTTRVKPTTQSEVSPLFAGTDVIPAHQFPDELAAYHPTPPLSPELP
GSCRKEFKENKEPSPKAKRKRSVKISNVALDSMHWQNDSVQIIASVSDLKSMDEFLLKKVNDLDNEDSKKDTLVDVVFKKALKEFRQNIF
SFYSSALAMDDGKSIRYKDLYALFEQILEKTMRLEQRDSLGESPVRVWVNTFKVFLDEYMNEFKTSDCTATKVPKTERKKRRKKETDLVE
EHNGHIFKATQYSIPTYCEYCSSLIWIMDRASVCKLCKYACHKKCCLKTTAKCSKKYDPELSSRQFGVELSRLTSEDRTVPLVVEKLINY
IEMHGLYTEGIYRKSGSTNKIKELRQGLDTDAESVNLDDYNIHVIASVFKQWLRDLPNPLMTFELYEEFLRAMGLQERKETIRGVYSVID
QLSRTHLNTLERLIFHLVRIALQEDTNRMSANALAIVFAPCILRCPDTTDPLQSVQDISKTTTCVELIVVEQMNKYKARLKDISSLEFAE
NKAKTRLSLIRRSMGKGRIRRGNYPGPSSPVVVRLPSVSDVSEETLTSEAAMETDITEQQQAAMQQEERVLTEQIENLQKEKEELTFEML
VLEPRASDDETLESEASIGTADSSENLNMESEYAISEKSERSLALSSLKTAGKSEPSSKLRKQLKKQQDSLDVVDSSVSSLCLSNTASSH
GTRKLFQIYSKSPFYRAASGNEALGMEGPLGQTKFLEDKPQFISRGTFNPEKGKQKLKNVKNSPQKTKETPEGTVMSGRRKTVDPDCTSN

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>62842_62842_4_PARP6-MYO9A_PARP6_chr15_72545778_ENST00000287196_MYO9A_chr15_72260466_ENST00000564571_length(transcript)=7825nt_BP=1718nt
CAACAGAAACCAAGCAGCAACAGCCCTTGGAAAGAGGCTAAATTTTTCTTGACTTCTGCAGCAACAAAGACCGTGAAAAGTTGGCACTTC
TGGCCTAACGCTGCCGTCATCCTACCCCTCACCCCAGGGCAACCCAGGCTGGACATTTAGTGCCTCCCTCTTTATTCCTCTGTGATCATC
CAGATCAGCACTTGACTGTTTATTTTCAAATCTCACGAACCTCACCCCAAGATCTTCACATTCTGGATCTCAGCTGCTCTTGAAGGACAG
TGACTTGTTACCACCGCAACAGCAGAGCCTGCCATCCCCAACAGATCACCAGTTGTCCCTGACATCGTGCCCTACCTTGTCTCCCTTTGT
GGTCTCCTAAATGCCCATCTCGTTGGCCTTGGTTCGGCTAGTGGTATGGAGGGGTGCTGCCTAGCACTGACCTGAGAGTGTGTGTGACCC
ACTGACCCAATGGACATCAAAGGCCAGTTCTGGAATGATGACGACTCGGAGGGAGATAATGAATCAGAGGAATTTCTCTATGGCGTTCAG
GGGAGCTGTGCAGCTGACCTGTATCGACACCCACAGCTTGATGCAGACATTGAAGCCGTGAAGGAGATCTACAGTGAGAACTCTGTATCC
ATCAGAGAATATGGAACTATCGATGACGTGGACATTGACCTCCACATCAACATCAGCTTCCTCGATGAGGAAGTCTCTACAGCCTGGAAG
GTCCTCCGGACAGAACCTATTGTGTTGAGGCTGCGATTTTCTCTCTCCCAGTACCTAGATGGACCAGAACCATCCATTGAGGTTTTCCAG
CCATCAAATAAGGAAGGATTTGGGCTGGGTCTTCAGTTGAAAAAGATCCTGGGTATGTTTACATCCCAACAATGGAAACATCTGAGCAAT
GATTTCTTGAAGACCCAGCAGGAGAAGAGGCACAGTTGGTTCAAGGCAAGTGGTACCATCAAGAAGTTCCGAGCTGGCCTCAGCATCTTT
TCACCCATCCCCAAGTCTCCCAGTTTCCCTATCATACAGGACTCCATGCTGAAAGGCAAACTAGGTGTACCAGAGCTTCGGGTTGGGCGC
CTCATGAACCGTTCCATCTCCTGTACCATGAAGAACCCCAAAGTGGAAGTGTTTGGCTACCCTCCCAGCCCCCAGGCAGGTCTCCTGTGC
CCTCAGCACGTGGGCCTCCCTCCCCCAGCACGGACCTCTCCTTTGGTCAGTGGTCACTGCAAGAACATTCCCACTCTGGAGTATGGATTC
CTCGTTCAGATCATGAAGTATGCAGAACAGAGGATTCCAACATTGAATGAGTACTGTGTGGTGTGTGATGAGCAGCATGTCTTCCAAAAT
GGATCTATGCTGAAGCCAGCTGTCTGTACTCGTGAACTATGCGTTTTCTCCTTCTACACACTGGGCGTCATGTCTGGAGCTGCAGAGGAG
GTGGCCACTGGAGCAGAGGTGGTGGATCTGCTGGTGGCCATGTGTAGGGCAGCTTTAGAGTCCCCTAGAAAGAGCATCATCTTTGAGCCT
TATCCCTCTGTGGTGGACCCCACTGATCCCAAGACTCTGGCCTTTAACCCTAAGAAGAAGAATTATGAGCGGCTTCAGAAAGCTCTGGAT
AGTGTGATGTCTATTCGGGAGATGACCCAGGGCTCATATTTGGAAATCAAGAAACAGATGGACAAGTTGGATCCCCTGGCCCATCCTCTC
CTGCAGTGCTTTCCACAGGCTACAAATCAAACATTGCTAGACAAGTTTAAGCATCAACATGAAGATAATTCTTACATCGAATTTCCAGCC
GTGATGGAGCCTGCTTTCATTATAAAACATTATGCTGGAAAAGTAAAATATGGGGTAAAGGATTTCCGGGAAAAAAATACAGATCATATG
CGCCCAGACATTGTAGCTCTTCTGAGAAGCAGCAAGAATGCATTTATCTCTGGGATGATTGGAATTGATCCTGTAGCTGTTTTCCGATGG
GCAATTCTCCGAGCTTTTTTCAGAGCCATGGTTGCTTTCAGGGAAGCTGGGAAAAGAAACATTCACAGAAAAACTGGACATGATGATACA
GCGCCATGTGCAATTTTGAAAAGTATGGATAGTTTTAGCTTTCTCCAACACCCAGTCCACCAGAGGAGCTTAGAGATTCTGCAGAGATGC
AAGGAAGAGAAGTACAGTATAACCCGGAAAAATCCCAGAACACCTCTTTCTGATCTCCAGGGCATGAATGCTCTAAATGAAAAAAACCAA
CATGATACATTTGATATTGCCTGGAATGGCAGAACTGGGATTCGCCAGAGCAGACTATCAAGTGGCACCTCCTTGCTTGATAAAGATGGA
ATATTTGCTAATTCAACTAGCAGCAAACTCCTGGAGAGAGCCCATGGAATTCTCACGAGAAACAAAAATTTCAAATCCAAGCCTGCCCTT
CCAAAGCACTTGCTAGAAGTAAATTCTTTAAAGCACCTGACAAGACTGACACTACAAGATCGCATTACCAAGTCTCTTCTTCATTTACAC
AAGAAGAAAAAACCTCCCAGCATCAGTGCCCAGTTTCAGGCATCATTAAGCAAGCTAATGGAAACACTTGGTCAAGCAGAACCATATTTT
GTAAAATGCATTCGCTCTAATGCTGAAAAGCTGCCCTTAAGGTTCAGTGATGTCTTGGTACTTAGACAGCTTCGATACACCGGGATGCTG
GAAACAGTTCGAATTCGCCAATCAGGATACAGCTCCAAATATTCTTTCCAGGATTTTGTGAGCCACTTCCATGTACTTCTTCCCCGAAAT
ATTATTCCATCCAAATTTAACATTCAGGATTTCTTCAGGAAAATAAATCTTAATCCAGATAATTATCAAGTTGGAAAAACCATGGTCTTT
CTAAAGGAGCAGGAACGACAGCACTTACAAGATCTGCTTCACCAAGAGGTGCTCCGCAGAATCATATTGTTGCAGCGATGGTTCAGGGTC
TTGCTGTGTAGGCAGCATTTCCTCCATCTGAGACAAGCATCTGTTATTATCCAGAGATTCTGGAGGAATTACCTAAATCAGAAGCAAGTC
AGAGATGCAGCTGTGCAGAAGGATGCTTTTGTTATGGCTAGTGCAGCTGCTCTTCTCCAAGCTTCCTGGCGTGCTCACTTAGAGAGGCAG
CGGTACTTGGAGTTACGGGCTGCAGCCATCGTTATCCAGCAGAAATGGAGAGATTACTATAGGCGCAGGCACATGGCTGCTATTTGCATA
CAAGCAAGATGGAAAGCCTACAGGGAAAGTAAAAGGTACCAAGAACAAAGGAAAAAAATTATCCTTTTGCAATCAACATGTAGAGGATTC
AGAGCAAGACAAAGATTTAAAGCTTTAAAAGAACAAAGGCTAAGAGAAACAAAGCCAGAAGTTGGATTGGTGAATATTAAGGGATATGGA
TCTCTGGAAATTCAGGGTTCAGACCCTTCAGGATGGGAGGATTGTTCTTTTGACAACAGAATAAAAGCCATAGAGGAATGTAAATCTGTA
ATAGAGAGTAATCGAATTAGCCGTGAAAGTTCAGTGGACTGCTTGAAGGAGTCACCAAACAAGCAGCAGGAGAGAGCCCAAAGCCAGAGT
GGTGTGGACTTGCAGGAAGATGTGCTTGTAAGAGAGAGACCCAGATCCTTGGAGGATCTCCATCAGAAAAAAGTAGGCCGGGCTAAGAGA
GAAAGTAGGAGAATGAGAGAACTAGAGCAAGCTATATTTAGCTTAGAATTGCTGAAAGTTCGTTCTCTTGGTGGTATTTCTCCTTCAGAG
GATCGCAGATGGTCTACAGAATTGGTGCCTGAAGGCCTTCAGTCTCCACGGGGTACACCTGATAGTGAGAGCTCTCAAGGAAGCTTGGAA
CTTCTGAGCTATGAGGAAAGCCAAAAGAGCAAACTAGAGTCTGTCATTTCAGATGAAGGAGACTTGCAGTTTCCATCACCTAAGATATCC
AGCAGTCCAAAATTTGATTCACGGGACAATGCCCTCAGTGCCTCAAATGAGACTAGCAGTGCAGAGCATTTGAAGGATGGAACTATGAAG
GAAATGGTGGTCTGCAGTTCTGAGTCTATTACCTGTAAACCACAGCTGAAAGACTCCTTCATTTCAAATAGTCTACCTACTTTTTTTTAT
ATCCCCCAACAAGACCCACTGAAAACAAATTCCCAACTAGACACAAGTATCCAAAGAAACAAACTATTGGAAAATGAAGACACAGCGGGG
GAAGCTCTTACTTTGGATATCAACAGGGAAACTAGAAGGTATCACTGCTCAGGAAAAGATCAGATTGTTCCTTCTTTGAATACAGAGTCT
TCTAATCCTGTGCTTAAGAAGTTAGAAAAGCTAAACACTGAGAAGGAAGAAAGGCAAAAACAGTTGCAGCAACAGAATGAAAAAGAGATG
ATGGAACAGATTCGCCAGCAAACAGATATTTTAGAGAAGGAGCGCAAAGCCTTCAAGACAATTGAAAAGCCAAGAATTGGAGAGTGTTTG
GTGGCACCATCTTCCTATCAGTCAAAGCAAAGAGTAGAGAGGCCATCCTCTCTCCTCAGCTTAAATACCTCAAATAAGGGAGAACTTAAT
GTACTGGGGTCCCTATCATTAAAAGATGCAGCTCTTGCCCAAAAAGACAGTTCCTCTGCTCACTTACCCCCAAAGGACCGACCTGTCACC
GTGTTCTTTGAAAGAAAAGGAAGTCCATGCCAATCTAGTACTGTCAAGGAATTATCCAAGACAGACAGAATGGGCACCCAGCTGAATGTA
GCCTGTAAACTCTCAAATAATCGCATTTCAAAAAGAGAACACTTTAGGCCAACTCAGTCTTACAGCCACAATTCTGATGACCTTTCCAGA
GAGGGAAATGCTAGGCCCATTTTCTTCACTCCAAAGGACAATATGAGTATTCCCCTTGTCAGCAAAGAAGCCTTAAACAGTAAAAATCCT
CAACTCCATAAAGAAGATGAACCAGCATGGAAACCTGTGAAGTTAGCTGGGCCAGGCCAAAGAGAGACATCACAGCGATTTTCGTCAGTT
GATGAACAAGCAAAACTTCATAAGACTATGTCTCAAGGAGAGATTACCAAGTTGGCAGTGAGACAGAAGGCTTCAGATTCAGATATAAGA
CCTCAGAGAGCTAAGATGAGATTCTGGGCCAAAGGGAAACAAGGGGAGAAGAAGACTACCAGAGTGAAACCTACTACCCAGTCAGAGGTT
TCGCCACTCTTTGCAGGCACAGATGTGATTCCAGCTCATCAGTTTCCAGATGAATTAGCTGCATATCACCCAACACCTCCTTTGAGCCCA
GAACTGCCCGGCAGTTGCCGGAAGGAATTCAAAGAGAACAAAGAACCTTCTCCAAAGGCTAAGCGCAAGCGAAGTGTGAAGATTAGCAAC
GTGGCTTTGGATTCTATGCATTGGCAAAATGACTCTGTCCAGATCATAGCAAGTGTCAGTGATTTAAAAAGCATGGATGAATTTCTTCTG
AAAAAGGTGAATGACCTAGATAATGAAGACAGCAAGAAGGATACACTAGTGGATGTTGTATTTAAAAAAGCCCTGAAGGAATTTCGGCAG
AATATCTTCAGCTTTTATTCATCTGCATTGGCGATGGATGATGGGAAAAGCATACGGTATAAAGACCTCTATGCACTATTTGAACAGATT
CTGGAAAAGACGATGAGGCTTGAGCAGCGTGATTCACTGGGTGAATCTCCAGTGAGAGTTTGGGTCAACACTTTTAAAGTGTTTTTAGAT
GAATATATGAATGAATTCAAGACTTCAGATTGCACAGCCACAAAGGTGCCAAAAACAGAAAGAAAGAAAAGAAGGAAAAAGGAAACTGAT
TTGGTGGAAGAACACAATGGTCACATCTTTAAAGCCACCCAATATAGCATCCCTACATACTGTGAATACTGTTCTTCTTTGATATGGATA
ATGGACCGAGCCTCTGTTTGCAAATTATGCAAGTATGCTTGCCATAAGAAGTGCTGTCTGAAAACCACAGCCAAGTGCTCTAAAAAGTAT
GATCCAGAGCTGTCATCTCGACAATTTGGGGTTGAACTGTCCCGTTTGACCAGTGAAGACCGAACTGTTCCTTTAGTAGTGGAAAAGCTC
ATAAACTACATTGAAATGCATGGACTGTATACAGAAGGTATTTATCGAAAGTCTGGTTCGACTAATAAAATCAAGGAGCTTCGGCAGGGT
CTAGATACAGATGCTGAGAGTGTAAATCTAGATGACTATAACATACACGTCATTGCAAGTGTATTCAAACAATGGCTTCGAGATTTGCCC
AATCCTCTCATGACCTTTGAACTCTATGAGGAATTTCTTCGAGCTATGGGCCTTCAGGAGAGGAAGGAGACAATCCGTGGTGTATACTCT
GTGATTGATCAACTCTCCCGAACTCATCTCAATACACTGGAACGCCTCATCTTTCATCTAGTCAGGATTGCTCTGCAGGAAGACACTAAT
CGAATGTCTGCTAATGCTTTGGCCATTGTGTTTGCGCCCTGCATTCTCCGCTGCCCTGACACCACTGACCCACTACAAAGTGTACAGGAC
ATCAGTAAGACTACCACTTGTGTGGAACTGATTGTTGTGGAACAAATGAATAAATACAAGGCTCGTCTCAAAGATATCAGTAGCTTGGAA
TTTGCTGAGAATAAGGCAAAGACCAGGTTGTCACTGATTCGTAGATCAATGGGAAAGGGGCGTATTCGTCGAGGAAACTATCCAGGTCCA
TCGTCTCCTGTTGTAGTTCGGTTGCCTTCTGTGTCTGATGTCTCAGAGGAGACCTTGACTAGTGAGGCAGCCATGGAGACTGACATCACA
GAACAGCAGCAAGCAGCTATGCAGCAGGAGGAGAGAGTACTGACTGAGCAGATTGAGAACCTACAGAAGGAGAAGGAGGAGCTAACATTT
GAGATGCTTGTACTGGAACCCCGTGCCTCTGATGATGAAACCCTTGAGTCTGAGGCCTCCATTGGGACTGCTGATAGCTCAGAGAATTTG
AATATGGAGTCTGAATATGCTATCTCTGAGAAATCAGAAGCTTAGCCCTTAGCTCCCTGAAGACAGCTGGCAAGTCTGAACCTTCCAGCA
AGTTGCGAAAGCAACTTAAAAAGCAGCAAGACTCTTTAGATGTCGTGGACTCTTCGGTCTCCTCTTTATGTCTGTCTAACACGGCATCAT
CTCATGGGACCAGAAAACTATTTCAGATTTATTCCAAATCTCCATTCTACCGAGCTGCCTCAGGTAATGAGGCCCTGGGAATGGAAGGAC
CATTGGGCCAGACCAAATTCCTGGAAGACAAGCCTCAGTTCATCAGCAGAGGAACCTTCAACCCGGAAAAGGGCAAACAAAAATTAAAGA
ATGTGAAAAACTCACCTCAGAAAACCAAAGAGACCCCAGAGGGGACAGTCATGTCTGGCCGCAGAAAAACTGTGGACCCAGACTGCACCT
CCAACCAACAGCTAGCACTCTTTGGAAATAATGAATTTATGGTCTGAACCGGCAGATGTGTGTCCCTCCGTGGCTACAGAGTGGTAAACA
AATCTCACCTTTGGGGCTGCGTTTCATCACCTCGTCCACAATAGTCAATCCTAATTGTGGTCCTGCCTCTTTTCTAAGCATATGGCTAAG
ACTGTATGTGCTGAATTCCTGGGCCTCCTGCAGAAGCAGAAAGCCTGCTGGGGATGGTGCCAGCTGTGCCTTGGCTGTTGTATTTGAATT

>62842_62842_4_PARP6-MYO9A_PARP6_chr15_72545778_ENST00000287196_MYO9A_chr15_72260466_ENST00000564571_length(amino acids)=2201AA_BP=1
MDIKGQFWNDDDSEGDNESEEFLYGVQGSCAADLYRHPQLDADIEAVKEIYSENSVSIREYGTIDDVDIDLHINISFLDEEVSTAWKVLR
TEPIVLRLRFSLSQYLDGPEPSIEVFQPSNKEGFGLGLQLKKILGMFTSQQWKHLSNDFLKTQQEKRHSWFKASGTIKKFRAGLSIFSPI
PKSPSFPIIQDSMLKGKLGVPELRVGRLMNRSISCTMKNPKVEVFGYPPSPQAGLLCPQHVGLPPPARTSPLVSGHCKNIPTLEYGFLVQ
IMKYAEQRIPTLNEYCVVCDEQHVFQNGSMLKPAVCTRELCVFSFYTLGVMSGAAEEVATGAEVVDLLVAMCRAALESPRKSIIFEPYPS
VVDPTDPKTLAFNPKKKNYERLQKALDSVMSIREMTQGSYLEIKKQMDKLDPLAHPLLQCFPQATNQTLLDKFKHQHEDNSYIEFPAVME
PAFIIKHYAGKVKYGVKDFREKNTDHMRPDIVALLRSSKNAFISGMIGIDPVAVFRWAILRAFFRAMVAFREAGKRNIHRKTGHDDTAPC
AILKSMDSFSFLQHPVHQRSLEILQRCKEEKYSITRKNPRTPLSDLQGMNALNEKNQHDTFDIAWNGRTGIRQSRLSSGTSLLDKDGIFA
NSTSSKLLERAHGILTRNKNFKSKPALPKHLLEVNSLKHLTRLTLQDRITKSLLHLHKKKKPPSISAQFQASLSKLMETLGQAEPYFVKC
IRSNAEKLPLRFSDVLVLRQLRYTGMLETVRIRQSGYSSKYSFQDFVSHFHVLLPRNIIPSKFNIQDFFRKINLNPDNYQVGKTMVFLKE
QERQHLQDLLHQEVLRRIILLQRWFRVLLCRQHFLHLRQASVIIQRFWRNYLNQKQVRDAAVQKDAFVMASAAALLQASWRAHLERQRYL
ELRAAAIVIQQKWRDYYRRRHMAAICIQARWKAYRESKRYQEQRKKIILLQSTCRGFRARQRFKALKEQRLRETKPEVGLVNIKGYGSLE
IQGSDPSGWEDCSFDNRIKAIEECKSVIESNRISRESSVDCLKESPNKQQERAQSQSGVDLQEDVLVRERPRSLEDLHQKKVGRAKRESR
RMRELEQAIFSLELLKVRSLGGISPSEDRRWSTELVPEGLQSPRGTPDSESSQGSLELLSYEESQKSKLESVISDEGDLQFPSPKISSSP
KFDSRDNALSASNETSSAEHLKDGTMKEMVVCSSESITCKPQLKDSFISNSLPTFFYIPQQDPLKTNSQLDTSIQRNKLLENEDTAGEAL
TLDINRETRRYHCSGKDQIVPSLNTESSNPVLKKLEKLNTEKEERQKQLQQQNEKEMMEQIRQQTDILEKERKAFKTIEKPRIGECLVAP
SSYQSKQRVERPSSLLSLNTSNKGELNVLGSLSLKDAALAQKDSSSAHLPPKDRPVTVFFERKGSPCQSSTVKELSKTDRMGTQLNVACK
LSNNRISKREHFRPTQSYSHNSDDLSREGNARPIFFTPKDNMSIPLVSKEALNSKNPQLHKEDEPAWKPVKLAGPGQRETSQRFSSVDEQ
AKLHKTMSQGEITKLAVRQKASDSDIRPQRAKMRFWAKGKQGEKKTTRVKPTTQSEVSPLFAGTDVIPAHQFPDELAAYHPTPPLSPELP
GSCRKEFKENKEPSPKAKRKRSVKISNVALDSMHWQNDSVQIIASVSDLKSMDEFLLKKVNDLDNEDSKKDTLVDVVFKKALKEFRQNIF
SFYSSALAMDDGKSIRYKDLYALFEQILEKTMRLEQRDSLGESPVRVWVNTFKVFLDEYMNEFKTSDCTATKVPKTERKKRRKKETDLVE
EHNGHIFKATQYSIPTYCEYCSSLIWIMDRASVCKLCKYACHKKCCLKTTAKCSKKYDPELSSRQFGVELSRLTSEDRTVPLVVEKLINY
IEMHGLYTEGIYRKSGSTNKIKELRQGLDTDAESVNLDDYNIHVIASVFKQWLRDLPNPLMTFELYEEFLRAMGLQERKETIRGVYSVID
QLSRTHLNTLERLIFHLVRIALQEDTNRMSANALAIVFAPCILRCPDTTDPLQSVQDISKTTTCVELIVVEQMNKYKARLKDISSLEFAE
NKAKTRLSLIRRSMGKGRIRRGNYPGPSSPVVVRLPSVSDVSEETLTSEAAMETDITEQQQAAMQQEERVLTEQIENLQKEKEELTFEML

--------------------------------------------------------------
>62842_62842_5_PARP6-MYO9A_PARP6_chr15_72545778_ENST00000287196_MYO9A_chr15_72260466_ENST00000566885_length(transcript)=5562nt_BP=1718nt
CAACAGAAACCAAGCAGCAACAGCCCTTGGAAAGAGGCTAAATTTTTCTTGACTTCTGCAGCAACAAAGACCGTGAAAAGTTGGCACTTC
TGGCCTAACGCTGCCGTCATCCTACCCCTCACCCCAGGGCAACCCAGGCTGGACATTTAGTGCCTCCCTCTTTATTCCTCTGTGATCATC
CAGATCAGCACTTGACTGTTTATTTTCAAATCTCACGAACCTCACCCCAAGATCTTCACATTCTGGATCTCAGCTGCTCTTGAAGGACAG
TGACTTGTTACCACCGCAACAGCAGAGCCTGCCATCCCCAACAGATCACCAGTTGTCCCTGACATCGTGCCCTACCTTGTCTCCCTTTGT
GGTCTCCTAAATGCCCATCTCGTTGGCCTTGGTTCGGCTAGTGGTATGGAGGGGTGCTGCCTAGCACTGACCTGAGAGTGTGTGTGACCC
ACTGACCCAATGGACATCAAAGGCCAGTTCTGGAATGATGACGACTCGGAGGGAGATAATGAATCAGAGGAATTTCTCTATGGCGTTCAG
GGGAGCTGTGCAGCTGACCTGTATCGACACCCACAGCTTGATGCAGACATTGAAGCCGTGAAGGAGATCTACAGTGAGAACTCTGTATCC
ATCAGAGAATATGGAACTATCGATGACGTGGACATTGACCTCCACATCAACATCAGCTTCCTCGATGAGGAAGTCTCTACAGCCTGGAAG
GTCCTCCGGACAGAACCTATTGTGTTGAGGCTGCGATTTTCTCTCTCCCAGTACCTAGATGGACCAGAACCATCCATTGAGGTTTTCCAG
CCATCAAATAAGGAAGGATTTGGGCTGGGTCTTCAGTTGAAAAAGATCCTGGGTATGTTTACATCCCAACAATGGAAACATCTGAGCAAT
GATTTCTTGAAGACCCAGCAGGAGAAGAGGCACAGTTGGTTCAAGGCAAGTGGTACCATCAAGAAGTTCCGAGCTGGCCTCAGCATCTTT
TCACCCATCCCCAAGTCTCCCAGTTTCCCTATCATACAGGACTCCATGCTGAAAGGCAAACTAGGTGTACCAGAGCTTCGGGTTGGGCGC
CTCATGAACCGTTCCATCTCCTGTACCATGAAGAACCCCAAAGTGGAAGTGTTTGGCTACCCTCCCAGCCCCCAGGCAGGTCTCCTGTGC
CCTCAGCACGTGGGCCTCCCTCCCCCAGCACGGACCTCTCCTTTGGTCAGTGGTCACTGCAAGAACATTCCCACTCTGGAGTATGGATTC
CTCGTTCAGATCATGAAGTATGCAGAACAGAGGATTCCAACATTGAATGAGTACTGTGTGGTGTGTGATGAGCAGCATGTCTTCCAAAAT
GGATCTATGCTGAAGCCAGCTGTCTGTACTCGTGAACTATGCGTTTTCTCCTTCTACACACTGGGCGTCATGTCTGGAGCTGCAGAGGAG
GTGGCCACTGGAGCAGAGGTGGTGGATCTGCTGGTGGCCATGTGTAGGGCAGCTTTAGAGTCCCCTAGAAAGAGCATCATCTTTGAGCCT
TATCCCTCTGTGGTGGACCCCACTGATCCCAAGACTCTGGCCTTTAACCCTAAGAAGAAGAATTATGAGCGGCTTCAGAAAGCTCTGGAT
AGTGTGATGTCTATTCGGGAGATGACCCAGGGCTCATATTTGGAAATCAAGAAACAGATGGACAAGTTGGATCCCCTGGCCCATCCTCTC
CTGCAGTGCTTTCCACAGGCTACAAATCAAACATTGCTAGACAAGTTTAAGCATCAACATGAAGATAATTCTTACATCGAATTTCCAGCC
GTGATGGAGCCTGCTTTCATTATAAAACATTATGCTGGAAAAGTAAAATATGGGGTAAAGGATTTCCGGGAAAAAAATACAGATCATATG
CGCCCAGACATTGTAGCTCTTCTGAGAAGCAGCAAGAATGCATTTATCTCTGGGATGATTGGAATTGATCCTGTAGCTGTTTTCCGATGG
GCAATTCTCCGAGCTTTTTTCAGAGCCATGGTTGCTTTCAGGGAAGCTGGGAAAAGAAACATTCACAGAAAAACTGGACATGATGATACA
GCGCCATGTGCAATTTTGAAAAGTATGGATAGTTTTAGCTTTCTCCAACACCCAGTCCACCAGAGGAGCTTAGAGATTCTGCAGAGATGC
AAGGAAGAGAAGTACAGTAAGGCTACAAATCCTGATAAACTGTTATCACATATCCATTTGGAAATGGAAACCAGGAGCATCCTACACCAG
GGTATAACCCGGAAAAATCCCAGAACACCTCTTTCTGATCTCCAGGGCATGAATGCTCTAAATGAAAAAAACCAACATGATACATTTGAT
ATTGCCTGGAATGGCAGAACTGGGATTCGCCAGAGCAGACTATCAAGTGGCACCTCCTTGCTTGATAAAGATGGAATATTTGCTAATTCA
ACTAGCAGCAAACTCCTGGAGAGAGCCCATGGAATTCTCACGAGAAACAAAAATTTCAAATCCAAGCCTGCCCTTCCAAAGCACTTGCTA
GAAGTAAATTCTTTAAAGCACCTGACAAGACTGACACTACAAGATCGCATTACCAAGTCTCTTCTTCATTTACACAAGAAGAAAAAACCT
CCCAGCATCAGTGCCCAGTTTCAGGCATCATTAAGCAAGCTAATGGAAACACTTGGTCAAGCAGAACCATATTTTGTAAAATGCATTCGC
TCTAATGCTGAAAAGCTGCCCTTAAGGTTCAGTGATGTCTTGGTACTTAGACAGCTTCGATACACCGGGATGCTGGAAACAGTTCGAATT
CGCCAATCAGGATACAGCTCCAAATATTCTTTCCAGGATTTTGTGAGCCACTTCCATGTACTTCTTCCCCGAAATATTATTCCATCCAAA
TTTAACATTCAGGATTTCTTCAGGAAAATAAATCTTAATCCAGATAATTATCAAGTTGGAAAAACCATGGTCTTTCTAAAGGAGCAGGAA
CGACAGCACTTACAAGATCTGCTTCACCAAGAGGTGCTCCGCAGAATCATATTGTTGCAGCGATGGTTCAGGGTCTTGCTGTGTAGGCAG
CATTTCCTCCATCTGAGACAAGCATCTGTTATTATCCAGAGATTCTGGAGGAATTACCTAAATCAGAAGCAAGTCAGAGATGCAGCTGTG
CAGAAGGATGCTTTTGTTATGGCTAGTGCAGCTGCTCTTCTCCAAGCTTCCTGGCGTGCTCACTTAGAGAGGCAGCGGTACTTGGAGTTA
CGGGCTGCAGCCATCGTTATCCAGCAGAAATGGAGAGATTACTATAGGCGCAGGCACATGGCTGCTATTTGCATACAAGCAAGATGGAAA
GCCTACAGGGAAAGTAAAAGGTACCAAGAACAAAGGAAAAAAATTATCCTTTTGCAATCAACATGTAGAGGATTCAGAGCAAGACAAAGA
TTTAAAGCTTTAAAAGAACAAAGGCTAAGAGAAACAAAGCCAGAAGTTGGATTGGTGAATATTAAGGGATATGGATCTCTGGAAATTCAG
GGTTCAGACCCTTCAGGATGGGAGGATTGTTCTTTTGACAACAGAATAAAAGCCATAGAGGAATGTAAATCTGTAATAGAGAGTAATCGA
ATTAGCCGTGAAAGTTCAGTGGACTGCTTGAAGGAGTCACCAAACAAGCAGCAGGAGAGAGCCCAAAGCCAGAGTGGTGTGGACTTGCAG
GAAGATGTGCTTGTAAGAGAGAGACCCAGATCCTTGGAGGATCTCCATCAGAAAAAAGTAGGCCGGGCTAAGAGAGAAAGTAGGAGAATG
AGAGAACTAGAGCAAGCTATATTTAGCTTAGAATTGCTGAAAGTTCGTTCTCTTGGTGGTATTTCTCCTTCAGAGGATCGCAGATGGTCT
ACAGAATTGGTGCCTGAAGGCCTTCAGTCTCCACGGGGTACACCTGATAGTGAGAGCTCTCAAGGAAGCTTGGAACTTCTGAGCTATGAG
GAAAGCCAAAAGAGCAAACTAGAGTCTGTCATTTCAGATGAAGGAGACTTGCAGTTTCCATCACCTAAGATATCCAGCAGTCCAAAATTT
GATTCACGGGACAATGCCCTCAGTGCCTCAAATGAGACTAGCAGTGCAGAGCATTTGAAGGATGGAACTATGAAGGAAATGGTGGTCTGC
AGTTCTGAGTCTATTACCTGTAAACCACAGCTGAAAGACTCCTTCATTTCAAATAGTCTACCTACTTTTTTTTATATCCCCCAACAAGAC
CCACTGAAAACAAATTCCCAACTAGACACAAGTATCCAAAGAAACAAACTATTGGAAAATGAAGACACAGCGGGGGAAGCTCTTACTTTG
GATATCAACAGGGAAACTAGAAGGTATCACTGCTCAGGAAAAGATCAGATTGTTCCTTCTTTGAATACAGAGTCTTCTAATCCTGTGCTT
AAGAAGTTAGAAAAGCTAAACACTGAGAAGGAAGAAAGGCAAAAACAGTTGCAGCAACAGAATGAAAAAGAGATGATGGAACAGATTCGC
CAGCAAACAGATATTTTAGAGAAGGAGCGCAAAGCCTTCAAGACAATTGAAAAGCCAAGAATTGGAGAGTGTTTGGTGGCACCATCTTCC
TATCAGTCAAAGCAAAGAGTAGAGAGGCCATCCTCTCTCCTCAGCTTAAATACCTCAAATAAGGGAGAACTTAATGTACTGGGGTCCCTA
TCATTAAAAGATGCAGCTCTTGCCCAAAAAGACAGTTCCTCTGCTCACTTACCCCCAAAGGACCGACCTGTCACCGTGTTCTTTGAAAGA
AAAGGAAGTCCATGCCAATCTAGTACTGTCAAGGAATTATCCAAGACAGACAGAATGGGCACCCAGCTGAATGTAGCCTGTAAACTCTCA
AATAATCGCATTTCAAAAAGAGAACACTTTAGGCCAACTCAGTCTTACAGCCACAATTCTGATGACCTTTCCAGAGAGGGAAATGCTAGG
CCCATTTTCTTCACTCCAAAGGACAATATGAGTATTCCCCTGTAAGTGAAATGTTTATTTATGTATAAATGGGAAACTTCTTGGAGTATT
TTTATTAAGGTGCCTTGTTCTGCTCCAACTATTTGTGTAAAGTGGCTGCTCAACTTGGCCATTTTCTCTTTGTAAAAATATTCCCTAATT
GTTGACTCTACCATCACCTGAAGTTGGATGTAGTTATATCCTAGGAATCCTTGACTGATCATGAATAGCAGAGTAAATACTGGGTTCCTC
CCCATTAAGTGAGAAGCATTTGTGAAGGGCAGTACAGTGCCTATAAACATAGTAGGCATTCACCGAATACTGGTTGCTTTACAGCTGTGA
AGTTTAGTAGTTGAAGGTTGTTTGTTTCAGGCTTTAAAGAAGTTAATTTGTTTTGTTACAGCTGTTGGCCTATTTATGGTCATCATTACG
TTCATTATACTTCTTTGTATGTGATAAACACATAACATAAAATTTCCCATCTTAACCATTTTTAAATAATATAGTACAGTAGTGTTAACT

>62842_62842_5_PARP6-MYO9A_PARP6_chr15_72545778_ENST00000287196_MYO9A_chr15_72260466_ENST00000566885_length(amino acids)=1511AA_BP=1
MDIKGQFWNDDDSEGDNESEEFLYGVQGSCAADLYRHPQLDADIEAVKEIYSENSVSIREYGTIDDVDIDLHINISFLDEEVSTAWKVLR
TEPIVLRLRFSLSQYLDGPEPSIEVFQPSNKEGFGLGLQLKKILGMFTSQQWKHLSNDFLKTQQEKRHSWFKASGTIKKFRAGLSIFSPI
PKSPSFPIIQDSMLKGKLGVPELRVGRLMNRSISCTMKNPKVEVFGYPPSPQAGLLCPQHVGLPPPARTSPLVSGHCKNIPTLEYGFLVQ
IMKYAEQRIPTLNEYCVVCDEQHVFQNGSMLKPAVCTRELCVFSFYTLGVMSGAAEEVATGAEVVDLLVAMCRAALESPRKSIIFEPYPS
VVDPTDPKTLAFNPKKKNYERLQKALDSVMSIREMTQGSYLEIKKQMDKLDPLAHPLLQCFPQATNQTLLDKFKHQHEDNSYIEFPAVME
PAFIIKHYAGKVKYGVKDFREKNTDHMRPDIVALLRSSKNAFISGMIGIDPVAVFRWAILRAFFRAMVAFREAGKRNIHRKTGHDDTAPC
AILKSMDSFSFLQHPVHQRSLEILQRCKEEKYSKATNPDKLLSHIHLEMETRSILHQGITRKNPRTPLSDLQGMNALNEKNQHDTFDIAW
NGRTGIRQSRLSSGTSLLDKDGIFANSTSSKLLERAHGILTRNKNFKSKPALPKHLLEVNSLKHLTRLTLQDRITKSLLHLHKKKKPPSI
SAQFQASLSKLMETLGQAEPYFVKCIRSNAEKLPLRFSDVLVLRQLRYTGMLETVRIRQSGYSSKYSFQDFVSHFHVLLPRNIIPSKFNI
QDFFRKINLNPDNYQVGKTMVFLKEQERQHLQDLLHQEVLRRIILLQRWFRVLLCRQHFLHLRQASVIIQRFWRNYLNQKQVRDAAVQKD
AFVMASAAALLQASWRAHLERQRYLELRAAAIVIQQKWRDYYRRRHMAAICIQARWKAYRESKRYQEQRKKIILLQSTCRGFRARQRFKA
LKEQRLRETKPEVGLVNIKGYGSLEIQGSDPSGWEDCSFDNRIKAIEECKSVIESNRISRESSVDCLKESPNKQQERAQSQSGVDLQEDV
LVRERPRSLEDLHQKKVGRAKRESRRMRELEQAIFSLELLKVRSLGGISPSEDRRWSTELVPEGLQSPRGTPDSESSQGSLELLSYEESQ
KSKLESVISDEGDLQFPSPKISSSPKFDSRDNALSASNETSSAEHLKDGTMKEMVVCSSESITCKPQLKDSFISNSLPTFFYIPQQDPLK
TNSQLDTSIQRNKLLENEDTAGEALTLDINRETRRYHCSGKDQIVPSLNTESSNPVLKKLEKLNTEKEERQKQLQQQNEKEMMEQIRQQT
DILEKERKAFKTIEKPRIGECLVAPSSYQSKQRVERPSSLLSLNTSNKGELNVLGSLSLKDAALAQKDSSSAHLPPKDRPVTVFFERKGS

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Fusion Gene PPI Analysis for PARP6-MYO9A


check button Go to ChiPPI (Chimeric Protein-Protein interactions) to see the chimeric PPI interaction in

ChiPPI page.


check button Protein-protein interactors with each fusion partner protein in wild-type (BIOGRID-3.4.160)
HgeneHgene's interactorsTgeneTgene's interactors


check button - Retained PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenStill interaction with


check button - Lost PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


check button - Retained PPIs, but lost function due to frame-shift fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


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Related Drugs for PARP6-MYO9A


check button Drugs targeting genes involved in this fusion gene.
(DrugBank Version 5.1.8 2021-05-08)
PartnerGeneUniProtAccDrugBank IDDrug nameDrug activityDrug typeDrug status

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Related Diseases for PARP6-MYO9A


check button Diseases associated with fusion partners.
(DisGeNet 4.0)
PartnerGeneDisease IDDisease name# pubmedsSource