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Center for Computational Systems Medicine
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Fusion Gene Summary

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Fusion Gene ORF analysis

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Fusion Genomic Features

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Fusion Protein Features

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Fusion Gene Sequence

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Fusion Gene PPI analysis

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Related Drugs

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Related Diseases

Fusion gene:PBRM1-TMEM110 (FusionGDB2 ID:63011)

Fusion Gene Summary for PBRM1-TMEM110

check button Fusion gene summary
Fusion gene informationFusion gene name: PBRM1-TMEM110
Fusion gene ID: 63011
HgeneTgene
Gene symbol

PBRM1

TMEM110

Gene ID

55193

375346

Gene namepolybromo 1STIM activating enhancer
SynonymsBAF180|PB1TMEM110
Cytomap

3p21.1

3p21.1

Type of geneprotein-codingprotein-coding
Descriptionprotein polybromo-1BRG1-associated factor 180polybromo-1Dstore-operated calcium entry regulator STIMATESTIM-activating enhancer encoded by TMEM110transmembrane protein 110
Modification date2020031320200313
UniProtAcc..
Ensembl transtripts involved in fusion geneENST00000296302, ENST00000337303, 
ENST00000356770, ENST00000394830, 
ENST00000409057, ENST00000409114, 
ENST00000409767, ENST00000410007, 
ENST00000464769, ENST00000355083, 
Fusion gene scores* DoF score15 X 15 X 10=22504 X 2 X 3=24
# samples 194
** MAII scorelog2(19/2250*10)=-3.56585367777345
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0		log2(4/24*10)=0.736965594166206
effective Gene in Pan-Cancer Fusion Genes (eGinPCFGs).
DoF>8 and MAII>0
Context

PubMed: PBRM1 [Title/Abstract] AND TMEM110 [Title/Abstract] AND fusion [Title/Abstract]

Most frequent breakpointPBRM1(52584437)-TMEM110(52889460), # samples:2
Anticipated loss of major functional domain due to fusion event.PBRM1-TMEM110 seems lost the major protein functional domain in Hgene partner, which is a CGC due to the frame-shifted ORF.
PBRM1-TMEM110 seems lost the major protein functional domain in Hgene partner, which is a epigenetic factor due to the frame-shifted ORF.
PBRM1-TMEM110 seems lost the major protein functional domain in Hgene partner, which is a essential gene due to the frame-shifted ORF.
PBRM1-TMEM110 seems lost the major protein functional domain in Hgene partner, which is a IUPHAR drug target due to the frame-shifted ORF.
PBRM1-TMEM110 seems lost the major protein functional domain in Hgene partner, which is a tumor suppressor due to the frame-shifted ORF.
PBRM1-TMEM110 seems lost the major protein functional domain in Tgene partner, which is a essential gene due to the frame-shifted ORF.
* DoF score (Degree of Frequency) = # partners X # break points X # cancer types
** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10)

check button Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez
PartnerGeneGO IDGO termPubMed ID
TgeneTMEM110

GO:0032237

activation of store-operated calcium channel activity

26322679|26644574

TgeneTMEM110

GO:0035584

calcium-mediated signaling using intracellular calcium source

26644574

TgeneTMEM110

GO:0070886

positive regulation of calcineurin-NFAT signaling cascade

26644574


check buttonFusion gene breakpoints across PBRM1 (5'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.
all structure

check buttonFusion gene breakpoints across TMEM110 (3'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.
all structure

check button Fusion gene information from two resources (ChiTars 5.0 and ChimerDB 4.0)
* All genome coordinats were lifted-over on hg19.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
SourceDiseaseSampleHgeneHchrHbpHstrandTgeneTchrTbpTstrand
ChimerDB4LUADTCGA-55-8085-01APBRM1chr3

52584437

-TMEM110chr3

52889460

-


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Fusion Gene ORF analysis for PBRM1-TMEM110

check button Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
ORFHenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrand
5CDS-intronENST00000296302ENST00000464769PBRM1chr3

52584437

-TMEM110chr3

52889460

-
5CDS-intronENST00000337303ENST00000464769PBRM1chr3

52584437

-TMEM110chr3

52889460

-
5CDS-intronENST00000356770ENST00000464769PBRM1chr3

52584437

-TMEM110chr3

52889460

-
5CDS-intronENST00000394830ENST00000464769PBRM1chr3

52584437

-TMEM110chr3

52889460

-
5CDS-intronENST00000409057ENST00000464769PBRM1chr3

52584437

-TMEM110chr3

52889460

-
5CDS-intronENST00000409114ENST00000464769PBRM1chr3

52584437

-TMEM110chr3

52889460

-
5CDS-intronENST00000409767ENST00000464769PBRM1chr3

52584437

-TMEM110chr3

52889460

-
5CDS-intronENST00000410007ENST00000464769PBRM1chr3

52584437

-TMEM110chr3

52889460

-
Frame-shiftENST00000394830ENST00000355083PBRM1chr3

52584437

-TMEM110chr3

52889460

-
In-frameENST00000296302ENST00000355083PBRM1chr3

52584437

-TMEM110chr3

52889460

-
In-frameENST00000337303ENST00000355083PBRM1chr3

52584437

-TMEM110chr3

52889460

-
In-frameENST00000356770ENST00000355083PBRM1chr3

52584437

-TMEM110chr3

52889460

-
In-frameENST00000409057ENST00000355083PBRM1chr3

52584437

-TMEM110chr3

52889460

-
In-frameENST00000409114ENST00000355083PBRM1chr3

52584437

-TMEM110chr3

52889460

-
In-frameENST00000409767ENST00000355083PBRM1chr3

52584437

-TMEM110chr3

52889460

-
In-frameENST00000410007ENST00000355083PBRM1chr3

52584437

-TMEM110chr3

52889460

-

check buttonORFfinder result based on the fusion transcript sequence of in-frame fusion genes.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandSeq length
(transcript)		BP loci
(transcript)		Predicted start
(transcript)		Predicted stop
(transcript)		Seq length
(amino acids)
ENST00000356770PBRM1chr352584437-ENST00000355083TMEM110chr352889460-91024639353631786
ENST00000296302PBRM1chr352584437-ENST00000355083TMEM110chr352889460-93624899256231873
ENST00000337303PBRM1chr352584437-ENST00000355083TMEM110chr352889460-90424579353031766
ENST00000410007PBRM1chr352584437-ENST00000355083TMEM110chr352889460-91234660353841793
ENST00000409057PBRM1chr352584437-ENST00000355083TMEM110chr352889460-91984735354591818
ENST00000409114PBRM1chr352584437-ENST00000355083TMEM110chr352889460-92524789355131836
ENST00000409767PBRM1chr352584437-ENST00000355083TMEM110chr352889460-90874624353481781

check buttonDeepORF prediction of the coding potential based on the fusion transcript sequence of in-frame fusion genes. DeepORF is a coding potential classifier based on convolutional neural network by comparing the real Ribo-seq data. If the no-coding score < 0.5 and coding score > 0.5, then the in-frame fusion transcript is predicted as being likely translated.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandNo-coding scoreCoding score
ENST00000356770ENST00000355083PBRM1chr352584437-TMEM110chr352889460-0.0002026040.9997974
ENST00000296302ENST00000355083PBRM1chr352584437-TMEM110chr352889460-0.0004289940.999571
ENST00000337303ENST00000355083PBRM1chr352584437-TMEM110chr352889460-0.0002745870.9997254
ENST00000410007ENST00000355083PBRM1chr352584437-TMEM110chr352889460-0.00075430.99924576
ENST00000409057ENST00000355083PBRM1chr352584437-TMEM110chr352889460-0.0002090530.99979097
ENST00000409114ENST00000355083PBRM1chr352584437-TMEM110chr352889460-0.0003688360.99963117
ENST00000409767ENST00000355083PBRM1chr352584437-TMEM110chr352889460-0.0002790820.9997209

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Fusion Genomic Features for PBRM1-TMEM110


check buttonFusionAI prediction of the potential fusion gene breakpoint based on the pre-mature RNA sequence context (+/- 5kb of individual partner genes, total 20kb length sequence). FusionAI is a fusion gene breakpoint classifier based on convolutional neural network by comparing the fusion positive and negative sequence context of ~ 20K fusion gene data. From here, we can have the relative potentency of the 20K genomic sequence how individual sequnce will be likely used as the gene fusion breakpoints.
HgeneHchrHbpHstrandTgeneTchrTbpTstrand1-pp (fusion gene breakpoint)

check buttonDistribution of 44 human genomic features loci across 20kb length fusion breakpoint regions. We integrated a total of 44 different types of human genomic feature loci information across five big categories including virus integration sites, repeats, structural variants, chromatin states, and gene expression regulation. More details are in help page.
genomic feature

check buttonDistribution of 44 human genomic features loci across 20kb length fusion breakpoint regions that are ovelapped with the top 1% feature importance score regions. More details are in help page.

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Fusion Protein Features for PBRM1-TMEM110


check button Four levels of functional features of fusion genes
Go to FGviewer search page for the most frequent breakpoint (https://ccsmweb.uth.edu/FGviewer/chr3:52584437/chr3:52889460)
- FGviewer provides the online visualization of the retention search of the protein functional features across DNA, RNA, protein, and pathological levels.
- How to search
1. Put your fusion gene symbol.
2. Press the tab key until there will be shown the breakpoint information filled.
4. Go down and press 'Search' tab twice.
4. Go down to have the hyperlink of the search result.
5. Click the hyperlink.
6. See the FGviewer result for your fusion gene.
FGviewer

check buttonMain function of each fusion partner protein. (from UniProt)
HgeneTgene
..
FUNCTION: Transcriptional activator which is required for calcium-dependent dendritic growth and branching in cortical neurons. Recruits CREB-binding protein (CREBBP) to nuclear bodies. Component of the CREST-BRG1 complex, a multiprotein complex that regulates promoter activation by orchestrating a calcium-dependent release of a repressor complex and a recruitment of an activator complex. In resting neurons, transcription of the c-FOS promoter is inhibited by BRG1-dependent recruitment of a phospho-RB1-HDAC1 repressor complex. Upon calcium influx, RB1 is dephosphorylated by calcineurin, which leads to release of the repressor complex. At the same time, there is increased recruitment of CREBBP to the promoter by a CREST-dependent mechanism, which leads to transcriptional activation. The CREST-BRG1 complex also binds to the NR2B promoter, and activity-dependent induction of NR2B expression involves a release of HDAC1 and recruitment of CREBBP (By similarity). {ECO:0000250}.FUNCTION: Transcriptional activator which is required for calcium-dependent dendritic growth and branching in cortical neurons. Recruits CREB-binding protein (CREBBP) to nuclear bodies. Component of the CREST-BRG1 complex, a multiprotein complex that regulates promoter activation by orchestrating a calcium-dependent release of a repressor complex and a recruitment of an activator complex. In resting neurons, transcription of the c-FOS promoter is inhibited by BRG1-dependent recruitment of a phospho-RB1-HDAC1 repressor complex. Upon calcium influx, RB1 is dephosphorylated by calcineurin, which leads to release of the repressor complex. At the same time, there is increased recruitment of CREBBP to the promoter by a CREST-dependent mechanism, which leads to transcriptional activation. The CREST-BRG1 complex also binds to the NR2B promoter, and activity-dependent induction of NR2B expression involves a release of HDAC1 and recruitment of CREBBP (By similarity). {ECO:0000250}.

check buttonRetention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at

download page


* Minus value of BPloci means that the break pointn is located before the CDS.
- In-frame and retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
HgenePBRM1chr3:52584437chr3:52889460ENST00000296302-29301468_159916321690.0Compositional biasNote=Pro-rich
HgenePBRM1chr3:52584437chr3:52889460ENST00000296302-2930630_63316321690.0Compositional biasNote=Poly-Asp
HgenePBRM1chr3:52584437chr3:52889460ENST00000337303-2728630_63315251583.0Compositional biasNote=Poly-Asp
HgenePBRM1chr3:52584437chr3:52889460ENST00000356770-2728630_63315451603.0Compositional biasNote=Poly-Asp
HgenePBRM1chr3:52584437chr3:52889460ENST00000394830-2930630_63315251583.0Compositional biasNote=Poly-Asp
HgenePBRM1chr3:52584437chr3:52889460ENST00000409057-2829630_63315771635.0Compositional biasNote=Poly-Asp
HgenePBRM1chr3:52584437chr3:52889460ENST00000409114-2930630_63315951653.0Compositional biasNote=Poly-Asp
HgenePBRM1chr3:52584437chr3:52889460ENST00000409767-2829630_63315401598.0Compositional biasNote=Poly-Asp
HgenePBRM1chr3:52584437chr3:52889460ENST00000410007-2829630_63315521610.0Compositional biasNote=Poly-Asp
HgenePBRM1chr3:52584437chr3:52889460ENST00000296302-29301379_144716321690.0DNA bindingHMG box
HgenePBRM1chr3:52584437chr3:52889460ENST00000337303-27281379_144715251583.0DNA bindingHMG box
HgenePBRM1chr3:52584437chr3:52889460ENST00000356770-27281379_144715451603.0DNA bindingHMG box
HgenePBRM1chr3:52584437chr3:52889460ENST00000394830-29301379_144715251583.0DNA bindingHMG box
HgenePBRM1chr3:52584437chr3:52889460ENST00000409057-28291379_144715771635.0DNA bindingHMG box
HgenePBRM1chr3:52584437chr3:52889460ENST00000409114-29301379_144715951653.0DNA bindingHMG box
HgenePBRM1chr3:52584437chr3:52889460ENST00000409767-28291379_144715401598.0DNA bindingHMG box
HgenePBRM1chr3:52584437chr3:52889460ENST00000410007-28291379_144715521610.0DNA bindingHMG box
HgenePBRM1chr3:52584437chr3:52889460ENST00000296302-29301156_127216321690.0DomainBAH 2
HgenePBRM1chr3:52584437chr3:52889460ENST00000296302-2930200_27016321690.0DomainBromo 2
HgenePBRM1chr3:52584437chr3:52889460ENST00000296302-2930400_47016321690.0DomainBromo 3
HgenePBRM1chr3:52584437chr3:52889460ENST00000296302-2930538_60816321690.0DomainBromo 4
HgenePBRM1chr3:52584437chr3:52889460ENST00000296302-293064_13416321690.0DomainBromo 1
HgenePBRM1chr3:52584437chr3:52889460ENST00000296302-2930676_74616321690.0DomainBromo 5
HgenePBRM1chr3:52584437chr3:52889460ENST00000296302-2930792_86216321690.0DomainBromo 6
HgenePBRM1chr3:52584437chr3:52889460ENST00000296302-2930956_107416321690.0DomainBAH 1
HgenePBRM1chr3:52584437chr3:52889460ENST00000337303-27281156_127215251583.0DomainBAH 2
HgenePBRM1chr3:52584437chr3:52889460ENST00000337303-2728200_27015251583.0DomainBromo 2
HgenePBRM1chr3:52584437chr3:52889460ENST00000337303-2728400_47015251583.0DomainBromo 3
HgenePBRM1chr3:52584437chr3:52889460ENST00000337303-2728538_60815251583.0DomainBromo 4
HgenePBRM1chr3:52584437chr3:52889460ENST00000337303-272864_13415251583.0DomainBromo 1
HgenePBRM1chr3:52584437chr3:52889460ENST00000337303-2728676_74615251583.0DomainBromo 5
HgenePBRM1chr3:52584437chr3:52889460ENST00000337303-2728792_86215251583.0DomainBromo 6
HgenePBRM1chr3:52584437chr3:52889460ENST00000337303-2728956_107415251583.0DomainBAH 1
HgenePBRM1chr3:52584437chr3:52889460ENST00000356770-27281156_127215451603.0DomainBAH 2
HgenePBRM1chr3:52584437chr3:52889460ENST00000356770-2728200_27015451603.0DomainBromo 2
HgenePBRM1chr3:52584437chr3:52889460ENST00000356770-2728400_47015451603.0DomainBromo 3
HgenePBRM1chr3:52584437chr3:52889460ENST00000356770-2728538_60815451603.0DomainBromo 4
HgenePBRM1chr3:52584437chr3:52889460ENST00000356770-272864_13415451603.0DomainBromo 1
HgenePBRM1chr3:52584437chr3:52889460ENST00000356770-2728676_74615451603.0DomainBromo 5
HgenePBRM1chr3:52584437chr3:52889460ENST00000356770-2728792_86215451603.0DomainBromo 6
HgenePBRM1chr3:52584437chr3:52889460ENST00000356770-2728956_107415451603.0DomainBAH 1
HgenePBRM1chr3:52584437chr3:52889460ENST00000394830-29301156_127215251583.0DomainBAH 2
HgenePBRM1chr3:52584437chr3:52889460ENST00000394830-2930200_27015251583.0DomainBromo 2
HgenePBRM1chr3:52584437chr3:52889460ENST00000394830-2930400_47015251583.0DomainBromo 3
HgenePBRM1chr3:52584437chr3:52889460ENST00000394830-2930538_60815251583.0DomainBromo 4
HgenePBRM1chr3:52584437chr3:52889460ENST00000394830-293064_13415251583.0DomainBromo 1
HgenePBRM1chr3:52584437chr3:52889460ENST00000394830-2930676_74615251583.0DomainBromo 5
HgenePBRM1chr3:52584437chr3:52889460ENST00000394830-2930792_86215251583.0DomainBromo 6
HgenePBRM1chr3:52584437chr3:52889460ENST00000394830-2930956_107415251583.0DomainBAH 1
HgenePBRM1chr3:52584437chr3:52889460ENST00000409057-28291156_127215771635.0DomainBAH 2
HgenePBRM1chr3:52584437chr3:52889460ENST00000409057-2829200_27015771635.0DomainBromo 2
HgenePBRM1chr3:52584437chr3:52889460ENST00000409057-2829400_47015771635.0DomainBromo 3
HgenePBRM1chr3:52584437chr3:52889460ENST00000409057-2829538_60815771635.0DomainBromo 4
HgenePBRM1chr3:52584437chr3:52889460ENST00000409057-282964_13415771635.0DomainBromo 1
HgenePBRM1chr3:52584437chr3:52889460ENST00000409057-2829676_74615771635.0DomainBromo 5
HgenePBRM1chr3:52584437chr3:52889460ENST00000409057-2829792_86215771635.0DomainBromo 6
HgenePBRM1chr3:52584437chr3:52889460ENST00000409057-2829956_107415771635.0DomainBAH 1
HgenePBRM1chr3:52584437chr3:52889460ENST00000409114-29301156_127215951653.0DomainBAH 2
HgenePBRM1chr3:52584437chr3:52889460ENST00000409114-2930200_27015951653.0DomainBromo 2
HgenePBRM1chr3:52584437chr3:52889460ENST00000409114-2930400_47015951653.0DomainBromo 3
HgenePBRM1chr3:52584437chr3:52889460ENST00000409114-2930538_60815951653.0DomainBromo 4
HgenePBRM1chr3:52584437chr3:52889460ENST00000409114-293064_13415951653.0DomainBromo 1
HgenePBRM1chr3:52584437chr3:52889460ENST00000409114-2930676_74615951653.0DomainBromo 5
HgenePBRM1chr3:52584437chr3:52889460ENST00000409114-2930792_86215951653.0DomainBromo 6
HgenePBRM1chr3:52584437chr3:52889460ENST00000409114-2930956_107415951653.0DomainBAH 1
HgenePBRM1chr3:52584437chr3:52889460ENST00000409767-28291156_127215401598.0DomainBAH 2
HgenePBRM1chr3:52584437chr3:52889460ENST00000409767-2829200_27015401598.0DomainBromo 2
HgenePBRM1chr3:52584437chr3:52889460ENST00000409767-2829400_47015401598.0DomainBromo 3
HgenePBRM1chr3:52584437chr3:52889460ENST00000409767-2829538_60815401598.0DomainBromo 4
HgenePBRM1chr3:52584437chr3:52889460ENST00000409767-282964_13415401598.0DomainBromo 1
HgenePBRM1chr3:52584437chr3:52889460ENST00000409767-2829676_74615401598.0DomainBromo 5
HgenePBRM1chr3:52584437chr3:52889460ENST00000409767-2829792_86215401598.0DomainBromo 6
HgenePBRM1chr3:52584437chr3:52889460ENST00000409767-2829956_107415401598.0DomainBAH 1
HgenePBRM1chr3:52584437chr3:52889460ENST00000410007-28291156_127215521610.0DomainBAH 2
HgenePBRM1chr3:52584437chr3:52889460ENST00000410007-2829200_27015521610.0DomainBromo 2
HgenePBRM1chr3:52584437chr3:52889460ENST00000410007-2829400_47015521610.0DomainBromo 3
HgenePBRM1chr3:52584437chr3:52889460ENST00000410007-2829538_60815521610.0DomainBromo 4
HgenePBRM1chr3:52584437chr3:52889460ENST00000410007-282964_13415521610.0DomainBromo 1
HgenePBRM1chr3:52584437chr3:52889460ENST00000410007-2829676_74615521610.0DomainBromo 5
HgenePBRM1chr3:52584437chr3:52889460ENST00000410007-2829792_86215521610.0DomainBromo 6
HgenePBRM1chr3:52584437chr3:52889460ENST00000410007-2829956_107415521610.0DomainBAH 1
TgeneTMEM110chr3:52584437chr3:52889460ENST0000035508308149_15353295.0MotifGXXXG motif
TgeneTMEM110chr3:52584437chr3:52889460ENST0000035508308215_29453295.0Topological domainCytoplasmic
TgeneTMEM110chr3:52584437chr3:52889460ENST0000035508308102_12253295.0TransmembraneHelical
TgeneTMEM110chr3:52584437chr3:52889460ENST0000035508308156_17653295.0TransmembraneHelical
TgeneTMEM110chr3:52584437chr3:52889460ENST0000035508308194_21453295.0TransmembraneHelical
TgeneTMEM110chr3:52584437chr3:52889460ENST000003550830869_8953295.0TransmembraneHelical

- In-frame and not-retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
HgenePBRM1chr3:52584437chr3:52889460ENST00000337303-27281468_159915251583.0Compositional biasNote=Pro-rich
HgenePBRM1chr3:52584437chr3:52889460ENST00000356770-27281468_159915451603.0Compositional biasNote=Pro-rich
HgenePBRM1chr3:52584437chr3:52889460ENST00000394830-29301468_159915251583.0Compositional biasNote=Pro-rich
HgenePBRM1chr3:52584437chr3:52889460ENST00000409057-28291468_159915771635.0Compositional biasNote=Pro-rich
HgenePBRM1chr3:52584437chr3:52889460ENST00000409114-29301468_159915951653.0Compositional biasNote=Pro-rich
HgenePBRM1chr3:52584437chr3:52889460ENST00000409767-28291468_159915401598.0Compositional biasNote=Pro-rich
HgenePBRM1chr3:52584437chr3:52889460ENST00000410007-28291468_159915521610.0Compositional biasNote=Pro-rich
TgeneTMEM110chr3:52584437chr3:52889460ENST00000355083081_2853295.0Topological domainCytoplasmic
TgeneTMEM110chr3:52584437chr3:52889460ENST000003550830829_4953295.0TransmembraneHelical


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Fusion Gene Sequence for PBRM1-TMEM110


check button For in-frame fusion transcripts, we provide the fusion transcript sequences and fusion amino acid sequences. To have fusion amino acid sequence, we ran ORFfinder and chose the longest ORF among the all predicted ones.
>63011_63011_1_PBRM1-TMEM110_PBRM1_chr3_52584437_ENST00000296302_TMEM110_chr3_52889460_ENST00000355083_length(transcript)=9362nt_BP=4899nt
CCATGGGTTCCAAGAGAAGAAGAGCTACCTCCCCTTCCAGCAGTGTCAGCGGGGACTTTGATGATGGGCACCATTCTGTGTCAACACCAG
GCCCAAGCAGGAAAAGGAGGAGACTTTCCAATCTTCCAACTGTAGATCCTATTGCCGTGTGCCATGAACTCTATAATACCATCCGAGACT
ATAAGGATGAACAGGGCAGACTTCTCTGTGAGCTCTTCATTAGGGCACCAAAGCGAAGAAATCAACCAGACTATTATGAAGTGGTTTCTC
AGCCCATTGACTTGATGAAAATCCAACAGAAACTAAAAATGGAAGAGTATGATGATGTTAATTTGCTGACTGCTGACTTCCAGCTTCTTT
TTAACAATGCAAAGTCCTATTATAAGCCAGATTCTCCTGAATATAAAGCCGCTTGCAAACTCTGGGATTTGTACCTTCGAACAAGAAATG
AGTTTGTTCAGAAAGGAGAAGCAGATGACGAAGATGATGATGAAGATGGGCAAGACAATCAGGGCACAGTGACTGAAGGATCTTCTCCAG
CTTACTTGAAGGAGATCCTGGAGCAGCTTCTTGAAGCCATAGTTGTAGCTACAAATCCATCAGGACGTCTCATTAGCGAACTTTTTCAGA
AACTGCCTTCTAAAGTGCAATATCCAGATTATTATGCAATAATTAAGGAGCCTATAGATCTCAAGACCATTGCCCAGAGGATACAGAATG
GAAGCTACAAAAGTATTCATGCAATGGCCAAAGATATAGATCTCCTCGCAAAAAATGCCAAAACTTATAATGAGCCTGGCTCTCAAGTAT
TCAAGGATGCAAATTCAATTAAAAAAATATTTTATATGAAAAAGGCTGAAATTGAACATCATGAAATGGCTAAGTCAAGTCTTCGAATGA
GGACTCCATCCAACTTGGCTGCAGCCAGACTGACAGGTCCTTCACACAGTAAAGGCAGCCTTGGTGAAGAGAGAAATCCCACTAGCAAGT
ATTACCGTAATAAAAGAGCAGTACAAGGAGGTCGTTTATCAGCAATTACAATGGCACTTCAATATGGCTCAGAAAGTGAAGAAGATGCTG
CTTTAGCTGCTGCACGCTATGAAGAGGGAGAGTCAGAAGCAGAAAGCATCACTTCCTTTATGGATGTTTCAAATCCTTTTTATCAGCTTT
ATGACACAGTTAGGAGTTGTCGGAATAACCAAGGGCAGCTAATAGCTGAACCTTTTTACCATTTGCCTTCAAAGAAAAAATACCCTGATT
ATTACCAGCAAATTAAAATGCCCATATCACTACAACAGATCCGAACAAAACTGAAGAATCAAGAATATGAAACTTTAGATCATTTGGAGT
GTGATCTGAATTTAATGTTTGAAAATGCCAAACGCTATAATGTGCCCAATTCAGCCATCTACAAGCGAGTTCTAAAATTGCAGCAAGTTA
TGCAGGCAAAGAAGAAAGAGCTTGCCAGGAGAGACGATATCGAGGACGGAGACAGCATGATCTCTTCAGCCACCTCTGATACTGGTAGTG
CCAAAAGAAAAAGTAAAAAGAACATAAGAAAGCAGCGAATGAAAATCTTATTCAATGTTGTTCTTGAAGCTCGAGAGCCAGGTTCAGGCA
GAAGACTTTGTGACCTATTTATGGTTAAACCATCCAAAAAGGACTATCCTGATTATTATAAAATCATCTTGGAGCCAATGGACTTGAAAA
TAATTGAGCATAACATCCGCAATGACAAATATGCTGGTGAAGAGGGAATGATAGAAGACATGAAGCTGATGTTCCGGAATGCCAGGCACT
ATAATGAGGAGGGCTCCCAGGTTTATAATGATGCACATATCCTGGAGAAGTTACTCAAGGAGAAAAGGAAAGAGCTGGGCCCACTGCCTG
ATGATGATGACATGGCTTCTCCCAAACTCAAGCTGAGTAGGAAGAGTGGCATTTCTCCTAAAAAATCAAAATACATGACTCCAATGCAGC
AGAAACTAAATGAGGTCTATGAAGCTGTAAAGAACTATACTGATAAGAGGGGTCGCCGCCTCAGTGCCATATTTCTGAGGCTTCCCTCTA
GATCTGAGTTGCCTGACTACTATCTGACTATTAAAAAGCCCATGGACATGGAAAAAATTCGAAGTCACATGATGGCCAACAAGTACCAAG
ATATTGACTCTATGGTTGAGGACTTTGTCATGATGTTTAATAATGCCTGTACATACAATGAGCCGGAGTCTTTGATCTACAAAGATGCTC
TTGTTCTACACAAAGTCCTGCTTGAAACACGCAGAGACCTGGAGGGAGATGAGGACTCTCATGTCCCAAATGTGACTTTGCTGATTCAAG
AGCTTATCCACAATCTTTTTGTGTCAGTCATGAGTCATCAGGATGATGAGGGAAGATGCTACAGCGATTCTTTAGCAGAAATTCCTGCTG
TGGATCCCAACTTTCCTAACAAACCACCCCTTACATTTGACATAATTAGGAAGAATGTTGAAAATAATCGCTACCGTCGGCTTGATTTAT
TTCAAGAGCATATGTTTGAAGTATTGGAACGAGCAAGAAGGATGAATCGGACAGATTCAGAAATATATGAAGATGCAGTAGAACTTCAGC
AGTTTTTTATTAAAATTCGTGATGAACTCTGCAAAAATGGAGAGATTCTTCTTTCACCGGCACTCAGCTATACCACAAAACATTTGCATA
ATGATGTGGAGAAAGAGAGAAAGGAAAAATTGCCAAAAGAAATAGAGGAAGATAAACTAAAACGAGAAGAAGAAAAAAGAGAAGCTGAAA
AGAGTGAAGATTCCTCTGGTGCTGCAGGCCTCTCAGGCTTACATCGCACATACAGCCAGGACTGTAGCTTTAAAAACAGCATGTACCATG
TTGGAGATTACGTCTATGTGGAACCTGCAGAGGCCAACCTACAACCACATATCGTCTGTATTGAAAGACTGTGGGAGGATTCAGCTGGTG
AAAAATGGTTGTATGGCTGTTGGTTTTACCGACCAAATGAAACATTCCACCTGGCTACACGAAAATTTCTAGAAAAAGAAGTTTTTAAGA
GTGACTATTACAACAAAGTTCCAGTTAGTAAAATTCTAGGCAAGTGTGTGGTCATGTTTGTCAAGGAATACTTTAAGTTATGCCCAGAAA
ACTTCCGAGATGAGGATGTTTTTGTCTGTGAATCACGGTATTCTGCCAAAACCAAATCTTTTAAGAAAATTAAACTGTGGACCATGCCCA
TCAGCTCAGTCAGGTTTGTCCCTCGGGATGTGCCTCTGCCTGTGGTTCGCGTGGCCTCTGTATTTGCAAATGCAGATAAAGGTGATGATG
AGAAGAATACAGACAACTCAGAGGACAGTCGAGCTGAAGACAATTTTAACTTGGAAAAGGAAAAAGAAGATGTCCCTGTGGAAATGTCCA
ATGGTGAACCAGGTTGCCACTACTTTGAGCAGCTCCATTACAATGACATGTGGCTGAAGGTTGGCGACTGTGTCTTCATCAAGTCCCATG
GCCTGGTGCGTCCTCGTGTGGGCAGAATTGAAAAAGTATGGGTTCGAGATGGAGCTGCATATTTTTATGGCCCCATCTTCATTCACCCAG
AAGAAACAGAGCATGAGCCCACAAAAATGTTCTACAAAAAAGAAGTATTTCTGAGTAATCTGGAAGAAACCTGCCCCATGACATGTATTC
TCGGAAAGTGTGCTGTGTTGTCATTCAAGGACTTCCTCTCCTGCAGGCCAACTGAAATACCAGAAAATGACATTCTGCTTTGTGAGAGCC
GCTACAATGAGAGCGACAAGCAGATGAAGAAATTCAAAGGATTGAAGAGGTTTTCACTCTCTGCTAAAGTGGTAGATGATGAAATTTACT
ACTTCAGAAAACCAATTGTTCCTCAGAAGGAGCCATCACCTTTGCTGGAAAAGAAGATCCAGTTGCTAGAAGCTAAATTTGCCGAGTTAG
AAGGTGGAGATGATGATATTGAAGAGATGGGAGAAGAAGATAGTGAGGTCATTGAACCTCCTTCTCTACCTCAGCTTCAGACCCCCCTGG
CCAGTGAGCTGGACCTCATGCCCTACACACCCCCACAGTCTACCCCAAAGTCTGCCAAAGGCAGTGCAAAGAAGGAAGGCTCCAAACGGA
AAATCAACATGAGTGGCTACATCCTGTTCAGCAGTGAGATGAGGGCTGTGATTAAGGCCCAACACCCAGACTACTCTTTCGGGGAGCTCA
GCCGCCTGGTGGGGACAGAATGGAGAAATCTTGAGACAGCCAAGAAAGCAGAATATGAAGAGCGGGCAGCTAAAGTTGCTGAGCAGCAGG
AGAGAGAGCGAGCAGCACAGCAACAGCAGCCGAGTGCTTCTCCCCGAGCAGGCACCCCTGTGGGGGCTCTCATGGGGGTGGTGCCACCAC
CAACACCAATGGGGATGCTCAATCAGCAGTTGACACCTGTTGCAGGCATGATGGGTGGCTATCCGCCAGGCCTTCCACCTTTGCAGGGCC
CAGTTGATGGCCTTGTTAGCATGGGCAGCATGCAGCCACTTCACCCTGGGGGGCCTCCACCCCACCATCTTCCGCCAGGTGTGCCTGGCC
TCCCGGGCATCCCACCACCGGGTGTGATGAACCAAGGAGTGGCCCCTATGGTAGGGACTCCAGCACCAGGTGGAAGTCCATATGGACAAC
AGGTGGGAGTTTTGGGGCCTCCAGGGCAGCAGGCACCACCTCCATATCCCGGCCCACATCCAGCTGGACCCCCTGTCATACAGCAGCCAA
CAACACCCATGTTTGTAGCTCCCCCACCAAAGACCCAGCGGCTTCTTCACTCAGAGGCCTACCTGAAATACATTGAAGGACTCAGTGCGG
AGTCCAACAGCATTAGCAAGTGGGATCAGACACTGGCAGTCAAACGCTTCAGAGAACCAAAGCATGAAAGACGTCCGTGGAGGATATGGT
TTTTAGACACTTCCAAACAAGCCATAGGAATGCTGTTCATCCACTTTGCAAATGTATACCTAGCAGATCTCACTGAAGAGGACCCTTGTT
CACTGTACCTCATCAACTTCCTCCTGGACGCCACTGTGGGCATGCTGCTCATCTACGTGGGGGTGCGCGCCGTCAGCGTCCTGGTAGAGT
GGCAGCAGTGGGAGTCCCTGCGCTTCGGCGAATATGGAGACCCTCTGCAGTGTGGAGCCTGGGTCGGGCAGTGCGCTCTTTACATCGTGA
TCATGATTTTTGAAAAGTCTGTCGTCTTCATCGTCCTCCTAATACTTCAGTGGAAAAAGGTGGCCCTGTTGAATCCCATTGAAAACCCAG
ACTTGAAGCTGGCCATCGTCATGCTGATCGTCCCCTTCTTTGTCAACGCTTTGATGTTTTGGGTAGTGGACAATTTCCTCATGAGAAAGG
GGAAGACGAAAGCTAAGCTAGAAGAAAGGGGAGCCAACCAGGACTCGAGGAATGGGAGCAAGGTCCGCTACCGGAGGGCCGCATCCCACG
AGGAGTCTGAGTCTGAGATCCTGATCTCAGCGGATGATGAGATGGAGGAGTCCGACGTGGAGGAGGACCTCCGCAGACTGACCCCCCTCA
AGCCTGTGAAGAAAAAGAAGCACCGCTTTGGGCTACCCGTATGACACATTCCCATGCTGGGGGTGACGGGAGGGCCCCGCCAGCCGCTGG
TGTGCAGAGGTCATCCCGCAGCATCGTTCCTTACCCTCTCTCTGCCCTTCCTTTCTACCTCTGCTCCTCTTGCTGTCTCTGCCCGCTCTC
GCCTGCCCCCAGACTACTGTGACTTAAAAAGAGGGAAGAGGAGCCAGCGCCCGAGGGGGCCACTGGCGGCTGGAGGTCCCCATTCAGTTG
CACTACAAACACTGACCAAATATGCAAGGAAGGAGCTGTGTTTGTTTGTTGTCGTCCCAGACAGTGTTGTGAGGGACCTGAGGCCCTGCC
CCGTGTCCGACCACCGAGTGGCAAGGTGGAAGGAAGCACAGGCACACAGACCGTGGGTGGGTCTCCTCACCGTGGCTGTGGGCAGTGCGA
ACACATAACACCCTCGGGCTAAAAGTGACTCGTTGACCAAGTTGGAACCGGAATGCTTTCTTACTCAAAATGGCTTTTGTAACTATTGAT
TTCTGAAGCTGGTTTTATGAGTTGTGACAGTGTTACCAGGTTGGGGGTATGTGTTTATTTCCTACAAAGTACTTACGGGACTAATGGGCA
AAACAGAGATTTTTAAGTCTTCCGTATGCTGTTTGACTTTTATATTTTTAAGTTATATTTTCATACTATTGTATTTAAAAACTCTTTTTA
GTCCCCAAAGAAATGGGTTTATTTGCCTTTCATGGGGTGTGGGCTGGCAGGAGGAAAAATCGGGAGTTTTTTATTTGGAATATTATTAGA
TGATGCCCTATGATAAGATGAGACAAATGATGGGGAGGGAAGGAGGATGGCCCTTCTCTAGAATCAGCAAACCCAATGGTTCTGTGAAGG
TCAGACCCAAGCTTGGAGCAGCTGGTCTGGATGCAGATCCAGGAGCTGCAGAGTGTGGAACAGGAAAGGCTCTGCCCAGGGCCCATGAGC
TCTAGCATTCCTGCTGGCAGATTAGAGATCTTAGTTAAATTTGACCAAGAAAGGAGCTTAGCTAAGAGGTCTTTGTTTCCAGAGGACCCA
AGACTACCAGACTCCTGTGCAGTCTGCCTGTCTGCAGAGCCTCCAATCACGGTTTAAAGTGGTCTTGGCCTCCCAGCCCCCACTGCTGCA
GCCTTCAGAGCCAGCCTCTGGACTCAGCGCCAGGAGCCTCCTCTCCTGCTGCCCTGGTACCTGTCATCCTAGTGTCACCTATTTGTTTTG
CACAGCATTCTGGAGAACATGTGCCTCACAAAGTGATCCTGTTTTTCTCACCCTCCAAAGCTGAGGTGGCTAAGGGAGGCAGGGGTGAGA
GAGCTCACTCTCTAAACCACAGGCAGGGCAAGGTGCTTCTAGGCCGTGTCCCCTCCCTGGGGAATGGTCACTACTCCTCAGCATGGCCAC
AGGCCCCTGTGGTTTTGGGAGTTTGCTGAGTGACTGTGGAATGGGCTGACCCCAGCCGTTTCCCTGCTGTGGAAACAGCAAGGTAGGGGC
ACTGCTTGGTGGTTTGTCAAGCTCAGAGGCAGCCACGGATGGTTAGGAACAGGAAGCCACACTGCTAAGGTGTGATGAGCTAGAAGGGAG
ACATCCTGGACTTCAAGTGAGACAAGTGCAGAGGAGGCCACTCCACTTAGGACCTTCCTTTTAGACCTGCATGAGCACGTGTTTCACTTA
AGCACATTGGGTCCGAATTGGGCGCATGAACCCAGCTGTTAAACCAGGTACCCTGGGACTGCCCTCTGCCTCTCAGAGCCCTACCTGTCC
TGGACTTGAAGGCGAGCATCAGGCAGGCCTTCTCAGCCCATCTTCCACCAGGAGTGCAGAGCCAGGGTGCTGAGAGGAGCAGGGACTGTA
ACTACAGTAGGAGGCAACTTTGCTGGTGTCATTCCTGCTCGGATTGACTTTGTGCTCCCTCCCATCCACAGCTATGGTAGCCAGTATTTC
CCCAGCAGCTCTCTAGTGGGGAAGAGTGGCTAGAACCAGGCCATTCTCAGTCGAATTTAGGAAGACCAAGACTCATGTTCCTGACAGGAC
GGTCATTCCCTCATGGCATCACTGACTCAGTTCTAATTCCTCCCCTCCTGTTTCATTTTGGTTTGAACAACCTGTGCCTGCAGCTGTTTC
TTCCACCTTCCTGGAGCTCACAATTGGAGCTTCATGTTCAGTCTTGAGCTCCTAATGTTTCCAGACAGGGCAGGGGATAGGAGAGCCATA
ATCTATGAAAGCTGTGAAACAAACCCTGGGTTATATAGATCTCAGATGGTCTCATCTGAAGGCTTTGCCCACTTCCCAGTGAGCAGAGGG
TTTGGGGAACAAAGAGGTAGCTGAAGAGTGGTGGTTTTTCCCTGTATCCTGATTTTCAGAAAGGGCTTTAGTCTCTGAGCTGTGGCTAGT
AGCTGGCTGGCTGACCAGGGGACGGGGGTCTAATAGGGTGTCTGACCATAGGACACCTCTCGTGTTTGGCCTTCCCTTTCTTGTGTGTTT
GTGTGTGTGTGTGCACGTGCACGTGCACACACATGTACACACACAAATCTGTATCCCCAGGAGTGCCTCCTGCAGTCACTGGGGGCTCTT
CCGTGGTGCACCATCCCATGAGAGCAGATCAGAGGGCTGTGGTCAGGACTTCCTCCCGAGCTGCCCTCCCTCCCTGGGATGAGTTTCCTC
TCCACCTGCTCCAAGGTGCCTTACGAGGTGCAGCTCTTCACCTGGCCACATGGCATCCATCACCGTGTTGAGAAATGGTGGGACGTTGGC
TGGATATTGTGTGCTATGAATCTGATTTGTCCAAATCTGGACCTCAGCCAAGCCACCTGTGGTGGAACCTTGCAAGTCAAGGTCATGAAC
AAATTTCTTGTAACTATTGGAAATAAACTAATGAGGTAGAACTGTCATATCCAAATGGAAGAGGTGGTTGGTACTGTTACTTCCTTTTGC
TGTCAGAGGGTTGTTGACAATGGCAAGGGGGGATGTTAGTGAGATCCAGGTGGTGGTGGCTTCTTGGTCCACTCAGCTTGCACACATGCA
AGAGGAGGGTCTGTGGCCCCTCAGCCGTGCTGGTGGCCTCCTTCCTCAAGCTTTAACTTGTGCCCTCCCTGGCAACAGGGAGTCATGGGT
TAATGTCACCTGTCATGCCTCTTTCTTCAGGGAAAATATTAAAAGGCTCAAATCCAAGCTGTGACTTCCCTTAGACAGTGTAAGCCTGTA
GGGTGCAGCCCCAAGTTTATGTCCAAAGGCTGCCTCAGAACCCTGGAGGGAGCAGCGCCCAGCTGGCAGCTCACTCTGCCCTTGCAGTTC
ACTGGCCTTTTCGCAGCCAGGCTAAGATAGGCAGTGCAAGGAGCTTCCCACTGGCCAGAGCAGCTGCCTTGTAGAATGTGGGGCTGGCTT
TTAGAAGTTTCACACGCTTGCAGCTAAGAGTGCAGAGCTCTCTGTTTTACTTCGTGAAACATTAGCAGCTCTGAGGGGCTTGGCTTTTGG
TAAGGGACTTATGGTCTGACTTGCCACAAGCACCTTGAGCTCCTGGGTTGGTTGGTGGTTGGTTGGTTGGGTTGTTTTAAATTTGATTTT
TCTTTTCCTGAAGTTTGTTAGAAGTCAGACCTATGCAAGGAAAACCATGGCCCACTTCAGCAGCCATCCAGTGGGGGTGCTTAATCGGTG
GTGGTAGGATTCATGGAAACGTTTTTTTGAAATGAAAGAGAAGATGATGTACTTACATTGTAAAATGGTTTACAATAAAGTTTGGCATCT

>63011_63011_1_PBRM1-TMEM110_PBRM1_chr3_52584437_ENST00000296302_TMEM110_chr3_52889460_ENST00000355083_length(amino acids)=1873AA_BP=1630
MGSKRRRATSPSSSVSGDFDDGHHSVSTPGPSRKRRRLSNLPTVDPIAVCHELYNTIRDYKDEQGRLLCELFIRAPKRRNQPDYYEVVSQ
PIDLMKIQQKLKMEEYDDVNLLTADFQLLFNNAKSYYKPDSPEYKAACKLWDLYLRTRNEFVQKGEADDEDDDEDGQDNQGTVTEGSSPA
YLKEILEQLLEAIVVATNPSGRLISELFQKLPSKVQYPDYYAIIKEPIDLKTIAQRIQNGSYKSIHAMAKDIDLLAKNAKTYNEPGSQVF
KDANSIKKIFYMKKAEIEHHEMAKSSLRMRTPSNLAAARLTGPSHSKGSLGEERNPTSKYYRNKRAVQGGRLSAITMALQYGSESEEDAA
LAAARYEEGESEAESITSFMDVSNPFYQLYDTVRSCRNNQGQLIAEPFYHLPSKKKYPDYYQQIKMPISLQQIRTKLKNQEYETLDHLEC
DLNLMFENAKRYNVPNSAIYKRVLKLQQVMQAKKKELARRDDIEDGDSMISSATSDTGSAKRKSKKNIRKQRMKILFNVVLEAREPGSGR
RLCDLFMVKPSKKDYPDYYKIILEPMDLKIIEHNIRNDKYAGEEGMIEDMKLMFRNARHYNEEGSQVYNDAHILEKLLKEKRKELGPLPD
DDDMASPKLKLSRKSGISPKKSKYMTPMQQKLNEVYEAVKNYTDKRGRRLSAIFLRLPSRSELPDYYLTIKKPMDMEKIRSHMMANKYQD
IDSMVEDFVMMFNNACTYNEPESLIYKDALVLHKVLLETRRDLEGDEDSHVPNVTLLIQELIHNLFVSVMSHQDDEGRCYSDSLAEIPAV
DPNFPNKPPLTFDIIRKNVENNRYRRLDLFQEHMFEVLERARRMNRTDSEIYEDAVELQQFFIKIRDELCKNGEILLSPALSYTTKHLHN
DVEKERKEKLPKEIEEDKLKREEEKREAEKSEDSSGAAGLSGLHRTYSQDCSFKNSMYHVGDYVYVEPAEANLQPHIVCIERLWEDSAGE
KWLYGCWFYRPNETFHLATRKFLEKEVFKSDYYNKVPVSKILGKCVVMFVKEYFKLCPENFRDEDVFVCESRYSAKTKSFKKIKLWTMPI
SSVRFVPRDVPLPVVRVASVFANADKGDDEKNTDNSEDSRAEDNFNLEKEKEDVPVEMSNGEPGCHYFEQLHYNDMWLKVGDCVFIKSHG
LVRPRVGRIEKVWVRDGAAYFYGPIFIHPEETEHEPTKMFYKKEVFLSNLEETCPMTCILGKCAVLSFKDFLSCRPTEIPENDILLCESR
YNESDKQMKKFKGLKRFSLSAKVVDDEIYYFRKPIVPQKEPSPLLEKKIQLLEAKFAELEGGDDDIEEMGEEDSEVIEPPSLPQLQTPLA
SELDLMPYTPPQSTPKSAKGSAKKEGSKRKINMSGYILFSSEMRAVIKAQHPDYSFGELSRLVGTEWRNLETAKKAEYEERAAKVAEQQE
RERAAQQQQPSASPRAGTPVGALMGVVPPPTPMGMLNQQLTPVAGMMGGYPPGLPPLQGPVDGLVSMGSMQPLHPGGPPPHHLPPGVPGL
PGIPPPGVMNQGVAPMVGTPAPGGSPYGQQVGVLGPPGQQAPPPYPGPHPAGPPVIQQPTTPMFVAPPPKTQRLLHSEAYLKYIEGLSAE
SNSISKWDQTLAVKRFREPKHERRPWRIWFLDTSKQAIGMLFIHFANVYLADLTEEDPCSLYLINFLLDATVGMLLIYVGVRAVSVLVEW
QQWESLRFGEYGDPLQCGAWVGQCALYIVIMIFEKSVVFIVLLILQWKKVALLNPIENPDLKLAIVMLIVPFFVNALMFWVVDNFLMRKG

--------------------------------------------------------------
>63011_63011_2_PBRM1-TMEM110_PBRM1_chr3_52584437_ENST00000337303_TMEM110_chr3_52889460_ENST00000355083_length(transcript)=9042nt_BP=4579nt
TCCATGGGTTCCAAGAGAAGAAGAGCTACCTCCCCTTCCAGCAGTGTCAGCGGGGACTTTGATGATGGGCACCATTCTGTGTCAACACCA
GGCCCAAGCAGGAAAAGGAGGAGACTTTCCAATCTTCCAACTGTAGATCCTATTGCCGTGTGCCATGAACTCTATAATACCATCCGAGAC
TATAAGGATGAACAGGGCAGACTTCTCTGTGAGCTCTTCATTAGGGCACCAAAGCGAAGAAATCAACCAGACTATTATGAAGTGGTTTCT
CAGCCCATTGACTTGATGAAAATCCAACAGAAACTAAAAATGGAAGAGTATGATGATGTTAATTTGCTGACTGCTGACTTCCAGCTTCTT
TTTAACAATGCAAAGTCCTATTATAAGCCAGATTCTCCTGAATATAAAGCCGCTTGCAAACTCTGGGATTTGTACCTTCGAACAAGAAAT
GAGTTTGTTCAGAAAGGAGAAGCAGATGACGAAGATGATGATGAAGATGGGCAAGACAATCAGGGCACAGTGACTGAAGGATCTTCTCCA
GCTTACTTGAAGGAGATCCTGGAGCAGCTTCTTGAAGCCATAGTTGTAGCTACAAATCCATCAGGACGTCTCATTAGCGAACTTTTTCAG
AAACTGCCTTCTAAAGTGCAATATCCAGATTATTATGCAATAATTAAGGAGCCTATAGATCTCAAGACCATTGCCCAGAGGATACAGAAT
GGAAGCTACAAAAGTATTCATGCAATGGCCAAAGATATAGATCTCCTCGCAAAAAATGCCAAAACTTATAATGAGCCTGGCTCTCAAGTA
TTCAAGGATGCAAATTCAATTAAAAAAATATTTTATATGAAAAAGGCTGAAATTGAACATCATGAAATGGCTAAGTCAAGTCTTCGAATG
AGGACTCCATCCAACTTGGCTGCAGCCAGACTGACAGGTCCTTCACACAGTAAAGGCAGCCTTGGTGAAGAGAGAAATCCCACTAGCAAG
TATTACCGTAATAAAAGAGCAGTACAAGGAGGTCGTTTATCAGCAATTACAATGGCACTTCAATATGGCTCAGAAAGTGAAGAAGATGCT
GCTTTAGCTGCTGCACGCTATGAAGAGGGAGAGTCAGAAGCAGAAAGCATCACTTCCTTTATGGATGTTTCAAATCCTTTTTATCAGCTT
TATGACACAGTTAGGAGTTGTCGGAATAACCAAGGGCAGCTAATAGCTGAACCTTTTTACCATTTGCCTTCAAAGAAAAAATACCCTGAT
TATTACCAGCAAATTAAAATGCCCATATCACTACAACAGATCCGAACAAAACTGAAGAATCAAGAATATGAAACTTTAGATCATTTGGAG
TGTGATCTGAATTTAATGTTTGAAAATGCCAAACGCTATAATGTGCCCAATTCAGCCATCTACAAGCGAGTTCTAAAATTGCAGCAAGTT
ATGCAGGCAAAGAAGAAAGAGCTTGCCAGGAGAGACGATATCGAGGACGGAGACAGCATGATCTCTTCAGCCACCTCTGATACTGGTAGT
GCCAAAAGAAAAAGTAAAAAGAACATAAGAAAGCAGCGAATGAAAATCTTATTCAATGTTGTTCTTGAAGCTCGAGAGCCAGGTTCAGGC
AGAAGACTTTGTGACCTATTTATGGTTAAACCATCCAAAAAGGACTATCCTGATTATTATAAAATCATCTTGGAGCCAATGGACTTGAAA
ATAATTGAGCATAACATCCGCAATGACAAATATGCTGGTGAAGAGGGAATGATAGAAGACATGAAGCTGATGTTCCGGAATGCCAGGCAC
TATAATGAGGAGGGCTCCCAGGTTTATAATGATGCACATATCCTGGAGAAGTTACTCAAGGAGAAAAGGAAAGAGCTGGGCCCACTGCCT
GATGATGATGACATGGCTTCTCCCAAACTCAAGCTGAGTAGGAAGAGTGGCATTTCTCCTAAAAAATCAAAATACATGACTCCAATGCAG
CAGAAACTAAATGAGGTCTATGAAGCTGTAAAGAACTATACTGATAAGAGGGGTCGCCGCCTCAGTGCCATATTTCTGAGGCTTCCCTCT
AGATCTGAGTTGCCTGACTACTATCTGACTATTAAAAAGCCCATGGACATGGAAAAAATTCGAAGTCACATGATGGCCAACAAGTACCAA
GATATTGACTCTATGGTTGAGGACTTTGTCATGATGTTTAATAATGCCTGTACATACAATGAGCCGGAGTCTTTGATCTACAAAGATGCT
CTTGTTCTACACAAAGTCCTGCTTGAAACACGCAGAGACCTGGAGGGAGATGAGGACTCTCATGTCCCAAATGTGACTTTGCTGATTCAA
GAGCTTATCCACAATCTTTTTGTGTCAGTCATGAGTCATCAGGATGATGAGGGAAGATGCTACAGCGATTCTTTAGCAGAAATTCCTGCT
GTGGATCCCAACTTTCCTAACAAACCACCCCTTACATTTGACATAATTAGGAAGAATGTTGAAAATAATCGCTACCGTCGGCTTGATTTA
TTTCAAGAGCATATGTTTGAAGTATTGGAACGAGCAAGAAGGATGAATCGGACAGATTCAGAAATATATGAAGATGCAGTAGAACTTCAG
CAGTTTTTTATTAAAATTCGTGATGAACTCTGCAAAAATGGAGAGATTCTTCTTTCACCGGCACTCAGCTATACCACAAAACATTTGCAT
AATGATGTGGAGAAAGAGAGAAAGGAAAAATTGCCAAAAGAAATAGAGGAAGATAAACTAAAACGAGAAGAAGAAAAAAGAGAAGCTGAA
AAGAGTGAAGATTCCTCTGGTGCTGCAGGCCTCTCAGGCTTACATCGCACATACAGCCAGGACTGTAGCTTTAAAAACAGCATGTACCAT
GTTGGAGATTACGTCTATGTGGAACCTGCAGAGGCCAACCTACAACCACATATCGTCTGTATTGAAAGACTGTGGGAGGATTCAGCTGGT
GAAAAATGGTTGTATGGCTGTTGGTTTTACCGACCAAATGAAACATTCCACCTGGCTACACGAAAATTTCTAGAAAAAGAAGTTTTTAAG
AGTGACTATTACAACAAAGTTCCAGTTAGTAAAATTCTAGGCAAGTGTGTGGTCATGTTTGTCAAGGAATACTTTAAGTTATGCCCAGAA
AACTTCCGAGATGAGGATGTTTTTGTCTGTGAATCACGGTATTCTGCCAAAACCAAATCTTTTAAGAAAATTAAACTGTGGACCATGCCC
ATCAGCTCAGTCAGGTTTGTCCCTCGGGATGTGCCTCTGCCTGTGGTTCGCGTGGCCTCTGTATTTGCAAATGCAGATAAAGGTGATGAT
GAGAAGAATACAGACAACTCAGAGGACAGTCGAGCTGAAGACAATTTTAACTTGGAAAAGGAAAAAGAAGATGTCCCTGTGGAAATGTCC
AATGGTGAACCAGGTTGCCACTACTTTGAGCAGCTCCATTACAATGACATGTGGCTGAAGGTTGGCGACTGTGTCTTCATCAAGTCCCAT
GGCCTGGTGCGTCCTCGTGTGGGCAGAATTGAAAAAGTATGGGTTCGAGATGGAGCTGCATATTTTTATGGCCCCATCTTCATTCACCCA
GAAGAAACAGAGCATGAGCCCACAAAAATGTTCTACAAAAAAGAAGTATTTCTGAGTAATCTGGAAGAAACCTGCCCCATGACATGTATT
CTCGGAAAGTGTGCTGTGTTGTCATTCAAGGACTTCCTCTCCTGCAGGCCAACTGAAATACCAGAAAATGACATTCTGCTTTGTGAGAGC
CGCTACAATGAGAGCGACAAGCAGATGAAGAAATTCAAAGGATTGAAGAGGTTTTCACTCTCTGCTAAAGTGGTAGATGATGAAATTTAC
TACTTCAGAAAACCAATTGTTCCTCAGAAGGAGCCATCACCTTTGCTGGAAAAGAAGATCCAGTTGCTAGAAGCTAAATTTGCCGAGTTA
GAAGGTGGAGATGATGATATTGAAGAGATGGGAGAAGAAGATAGTGAGGTCATTGAACCTCCTTCTCTACCTCAGCTTCAGACCCCCCTG
GCCAGTGAGCTGGACCTCATGCCCTACACACCCCCACAGTCTACCCCAAAGTCTGCCAAAGGCAGTGCAAAGAAGGAAGGCTCCAAACGG
AAAATCAACATGAGTGGCTACATCCTGTTCAGCAGTGAGATGAGGGCTGTGATTAAGGCCCAACACCCAGACTACTCTTTCGGGGAGCTC
AGCCGCCTGGTGGGGACAGAATGGAGAAATCTTGAGACAGCCAAGAAAGCAGAATATGAAGGTGTGATGAACCAAGGAGTGGCCCCTATG
GTAGGGACTCCAGCACCAGGTGGAAGTCCATATGGACAACAGGTGGGAGTTTTGGGGCCTCCAGGGCAGCAGGCACCACCTCCATATCCC
GGCCCACATCCAGCTGGACCCCCTGTCATACAGCAGCCAACAACACCCATGTTTGTAGCTCCCCCACCAAAGACCCAGCGGCTTCTTCAC
TCAGAGGCCTACCTGAAATACATTGAAGGACTCAGTGCGGAGTCCAACAGCATTAGCAAGTGGGATCAGACACTGGCAGTCAAACGCTTC
AGAGAACCAAAGCATGAAAGACGTCCGTGGAGGATATGGTTTTTAGACACTTCCAAACAAGCCATAGGAATGCTGTTCATCCACTTTGCA
AATGTATACCTAGCAGATCTCACTGAAGAGGACCCTTGTTCACTGTACCTCATCAACTTCCTCCTGGACGCCACTGTGGGCATGCTGCTC
ATCTACGTGGGGGTGCGCGCCGTCAGCGTCCTGGTAGAGTGGCAGCAGTGGGAGTCCCTGCGCTTCGGCGAATATGGAGACCCTCTGCAG
TGTGGAGCCTGGGTCGGGCAGTGCGCTCTTTACATCGTGATCATGATTTTTGAAAAGTCTGTCGTCTTCATCGTCCTCCTAATACTTCAG
TGGAAAAAGGTGGCCCTGTTGAATCCCATTGAAAACCCAGACTTGAAGCTGGCCATCGTCATGCTGATCGTCCCCTTCTTTGTCAACGCT
TTGATGTTTTGGGTAGTGGACAATTTCCTCATGAGAAAGGGGAAGACGAAAGCTAAGCTAGAAGAAAGGGGAGCCAACCAGGACTCGAGG
AATGGGAGCAAGGTCCGCTACCGGAGGGCCGCATCCCACGAGGAGTCTGAGTCTGAGATCCTGATCTCAGCGGATGATGAGATGGAGGAG
TCCGACGTGGAGGAGGACCTCCGCAGACTGACCCCCCTCAAGCCTGTGAAGAAAAAGAAGCACCGCTTTGGGCTACCCGTATGACACATT
CCCATGCTGGGGGTGACGGGAGGGCCCCGCCAGCCGCTGGTGTGCAGAGGTCATCCCGCAGCATCGTTCCTTACCCTCTCTCTGCCCTTC
CTTTCTACCTCTGCTCCTCTTGCTGTCTCTGCCCGCTCTCGCCTGCCCCCAGACTACTGTGACTTAAAAAGAGGGAAGAGGAGCCAGCGC
CCGAGGGGGCCACTGGCGGCTGGAGGTCCCCATTCAGTTGCACTACAAACACTGACCAAATATGCAAGGAAGGAGCTGTGTTTGTTTGTT
GTCGTCCCAGACAGTGTTGTGAGGGACCTGAGGCCCTGCCCCGTGTCCGACCACCGAGTGGCAAGGTGGAAGGAAGCACAGGCACACAGA
CCGTGGGTGGGTCTCCTCACCGTGGCTGTGGGCAGTGCGAACACATAACACCCTCGGGCTAAAAGTGACTCGTTGACCAAGTTGGAACCG
GAATGCTTTCTTACTCAAAATGGCTTTTGTAACTATTGATTTCTGAAGCTGGTTTTATGAGTTGTGACAGTGTTACCAGGTTGGGGGTAT
GTGTTTATTTCCTACAAAGTACTTACGGGACTAATGGGCAAAACAGAGATTTTTAAGTCTTCCGTATGCTGTTTGACTTTTATATTTTTA
AGTTATATTTTCATACTATTGTATTTAAAAACTCTTTTTAGTCCCCAAAGAAATGGGTTTATTTGCCTTTCATGGGGTGTGGGCTGGCAG
GAGGAAAAATCGGGAGTTTTTTATTTGGAATATTATTAGATGATGCCCTATGATAAGATGAGACAAATGATGGGGAGGGAAGGAGGATGG
CCCTTCTCTAGAATCAGCAAACCCAATGGTTCTGTGAAGGTCAGACCCAAGCTTGGAGCAGCTGGTCTGGATGCAGATCCAGGAGCTGCA
GAGTGTGGAACAGGAAAGGCTCTGCCCAGGGCCCATGAGCTCTAGCATTCCTGCTGGCAGATTAGAGATCTTAGTTAAATTTGACCAAGA
AAGGAGCTTAGCTAAGAGGTCTTTGTTTCCAGAGGACCCAAGACTACCAGACTCCTGTGCAGTCTGCCTGTCTGCAGAGCCTCCAATCAC
GGTTTAAAGTGGTCTTGGCCTCCCAGCCCCCACTGCTGCAGCCTTCAGAGCCAGCCTCTGGACTCAGCGCCAGGAGCCTCCTCTCCTGCT
GCCCTGGTACCTGTCATCCTAGTGTCACCTATTTGTTTTGCACAGCATTCTGGAGAACATGTGCCTCACAAAGTGATCCTGTTTTTCTCA
CCCTCCAAAGCTGAGGTGGCTAAGGGAGGCAGGGGTGAGAGAGCTCACTCTCTAAACCACAGGCAGGGCAAGGTGCTTCTAGGCCGTGTC
CCCTCCCTGGGGAATGGTCACTACTCCTCAGCATGGCCACAGGCCCCTGTGGTTTTGGGAGTTTGCTGAGTGACTGTGGAATGGGCTGAC
CCCAGCCGTTTCCCTGCTGTGGAAACAGCAAGGTAGGGGCACTGCTTGGTGGTTTGTCAAGCTCAGAGGCAGCCACGGATGGTTAGGAAC
AGGAAGCCACACTGCTAAGGTGTGATGAGCTAGAAGGGAGACATCCTGGACTTCAAGTGAGACAAGTGCAGAGGAGGCCACTCCACTTAG
GACCTTCCTTTTAGACCTGCATGAGCACGTGTTTCACTTAAGCACATTGGGTCCGAATTGGGCGCATGAACCCAGCTGTTAAACCAGGTA
CCCTGGGACTGCCCTCTGCCTCTCAGAGCCCTACCTGTCCTGGACTTGAAGGCGAGCATCAGGCAGGCCTTCTCAGCCCATCTTCCACCA
GGAGTGCAGAGCCAGGGTGCTGAGAGGAGCAGGGACTGTAACTACAGTAGGAGGCAACTTTGCTGGTGTCATTCCTGCTCGGATTGACTT
TGTGCTCCCTCCCATCCACAGCTATGGTAGCCAGTATTTCCCCAGCAGCTCTCTAGTGGGGAAGAGTGGCTAGAACCAGGCCATTCTCAG
TCGAATTTAGGAAGACCAAGACTCATGTTCCTGACAGGACGGTCATTCCCTCATGGCATCACTGACTCAGTTCTAATTCCTCCCCTCCTG
TTTCATTTTGGTTTGAACAACCTGTGCCTGCAGCTGTTTCTTCCACCTTCCTGGAGCTCACAATTGGAGCTTCATGTTCAGTCTTGAGCT
CCTAATGTTTCCAGACAGGGCAGGGGATAGGAGAGCCATAATCTATGAAAGCTGTGAAACAAACCCTGGGTTATATAGATCTCAGATGGT
CTCATCTGAAGGCTTTGCCCACTTCCCAGTGAGCAGAGGGTTTGGGGAACAAAGAGGTAGCTGAAGAGTGGTGGTTTTTCCCTGTATCCT
GATTTTCAGAAAGGGCTTTAGTCTCTGAGCTGTGGCTAGTAGCTGGCTGGCTGACCAGGGGACGGGGGTCTAATAGGGTGTCTGACCATA
GGACACCTCTCGTGTTTGGCCTTCCCTTTCTTGTGTGTTTGTGTGTGTGTGTGCACGTGCACGTGCACACACATGTACACACACAAATCT
GTATCCCCAGGAGTGCCTCCTGCAGTCACTGGGGGCTCTTCCGTGGTGCACCATCCCATGAGAGCAGATCAGAGGGCTGTGGTCAGGACT
TCCTCCCGAGCTGCCCTCCCTCCCTGGGATGAGTTTCCTCTCCACCTGCTCCAAGGTGCCTTACGAGGTGCAGCTCTTCACCTGGCCACA
TGGCATCCATCACCGTGTTGAGAAATGGTGGGACGTTGGCTGGATATTGTGTGCTATGAATCTGATTTGTCCAAATCTGGACCTCAGCCA
AGCCACCTGTGGTGGAACCTTGCAAGTCAAGGTCATGAACAAATTTCTTGTAACTATTGGAAATAAACTAATGAGGTAGAACTGTCATAT
CCAAATGGAAGAGGTGGTTGGTACTGTTACTTCCTTTTGCTGTCAGAGGGTTGTTGACAATGGCAAGGGGGGATGTTAGTGAGATCCAGG
TGGTGGTGGCTTCTTGGTCCACTCAGCTTGCACACATGCAAGAGGAGGGTCTGTGGCCCCTCAGCCGTGCTGGTGGCCTCCTTCCTCAAG
CTTTAACTTGTGCCCTCCCTGGCAACAGGGAGTCATGGGTTAATGTCACCTGTCATGCCTCTTTCTTCAGGGAAAATATTAAAAGGCTCA
AATCCAAGCTGTGACTTCCCTTAGACAGTGTAAGCCTGTAGGGTGCAGCCCCAAGTTTATGTCCAAAGGCTGCCTCAGAACCCTGGAGGG
AGCAGCGCCCAGCTGGCAGCTCACTCTGCCCTTGCAGTTCACTGGCCTTTTCGCAGCCAGGCTAAGATAGGCAGTGCAAGGAGCTTCCCA
CTGGCCAGAGCAGCTGCCTTGTAGAATGTGGGGCTGGCTTTTAGAAGTTTCACACGCTTGCAGCTAAGAGTGCAGAGCTCTCTGTTTTAC
TTCGTGAAACATTAGCAGCTCTGAGGGGCTTGGCTTTTGGTAAGGGACTTATGGTCTGACTTGCCACAAGCACCTTGAGCTCCTGGGTTG
GTTGGTGGTTGGTTGGTTGGGTTGTTTTAAATTTGATTTTTCTTTTCCTGAAGTTTGTTAGAAGTCAGACCTATGCAAGGAAAACCATGG
CCCACTTCAGCAGCCATCCAGTGGGGGTGCTTAATCGGTGGTGGTAGGATTCATGGAAACGTTTTTTTGAAATGAAAGAGAAGATGATGT

>63011_63011_2_PBRM1-TMEM110_PBRM1_chr3_52584437_ENST00000337303_TMEM110_chr3_52889460_ENST00000355083_length(amino acids)=1766AA_BP=1523
MGSKRRRATSPSSSVSGDFDDGHHSVSTPGPSRKRRRLSNLPTVDPIAVCHELYNTIRDYKDEQGRLLCELFIRAPKRRNQPDYYEVVSQ
PIDLMKIQQKLKMEEYDDVNLLTADFQLLFNNAKSYYKPDSPEYKAACKLWDLYLRTRNEFVQKGEADDEDDDEDGQDNQGTVTEGSSPA
YLKEILEQLLEAIVVATNPSGRLISELFQKLPSKVQYPDYYAIIKEPIDLKTIAQRIQNGSYKSIHAMAKDIDLLAKNAKTYNEPGSQVF
KDANSIKKIFYMKKAEIEHHEMAKSSLRMRTPSNLAAARLTGPSHSKGSLGEERNPTSKYYRNKRAVQGGRLSAITMALQYGSESEEDAA
LAAARYEEGESEAESITSFMDVSNPFYQLYDTVRSCRNNQGQLIAEPFYHLPSKKKYPDYYQQIKMPISLQQIRTKLKNQEYETLDHLEC
DLNLMFENAKRYNVPNSAIYKRVLKLQQVMQAKKKELARRDDIEDGDSMISSATSDTGSAKRKSKKNIRKQRMKILFNVVLEAREPGSGR
RLCDLFMVKPSKKDYPDYYKIILEPMDLKIIEHNIRNDKYAGEEGMIEDMKLMFRNARHYNEEGSQVYNDAHILEKLLKEKRKELGPLPD
DDDMASPKLKLSRKSGISPKKSKYMTPMQQKLNEVYEAVKNYTDKRGRRLSAIFLRLPSRSELPDYYLTIKKPMDMEKIRSHMMANKYQD
IDSMVEDFVMMFNNACTYNEPESLIYKDALVLHKVLLETRRDLEGDEDSHVPNVTLLIQELIHNLFVSVMSHQDDEGRCYSDSLAEIPAV
DPNFPNKPPLTFDIIRKNVENNRYRRLDLFQEHMFEVLERARRMNRTDSEIYEDAVELQQFFIKIRDELCKNGEILLSPALSYTTKHLHN
DVEKERKEKLPKEIEEDKLKREEEKREAEKSEDSSGAAGLSGLHRTYSQDCSFKNSMYHVGDYVYVEPAEANLQPHIVCIERLWEDSAGE
KWLYGCWFYRPNETFHLATRKFLEKEVFKSDYYNKVPVSKILGKCVVMFVKEYFKLCPENFRDEDVFVCESRYSAKTKSFKKIKLWTMPI
SSVRFVPRDVPLPVVRVASVFANADKGDDEKNTDNSEDSRAEDNFNLEKEKEDVPVEMSNGEPGCHYFEQLHYNDMWLKVGDCVFIKSHG
LVRPRVGRIEKVWVRDGAAYFYGPIFIHPEETEHEPTKMFYKKEVFLSNLEETCPMTCILGKCAVLSFKDFLSCRPTEIPENDILLCESR
YNESDKQMKKFKGLKRFSLSAKVVDDEIYYFRKPIVPQKEPSPLLEKKIQLLEAKFAELEGGDDDIEEMGEEDSEVIEPPSLPQLQTPLA
SELDLMPYTPPQSTPKSAKGSAKKEGSKRKINMSGYILFSSEMRAVIKAQHPDYSFGELSRLVGTEWRNLETAKKAEYEGVMNQGVAPMV
GTPAPGGSPYGQQVGVLGPPGQQAPPPYPGPHPAGPPVIQQPTTPMFVAPPPKTQRLLHSEAYLKYIEGLSAESNSISKWDQTLAVKRFR
EPKHERRPWRIWFLDTSKQAIGMLFIHFANVYLADLTEEDPCSLYLINFLLDATVGMLLIYVGVRAVSVLVEWQQWESLRFGEYGDPLQC
GAWVGQCALYIVIMIFEKSVVFIVLLILQWKKVALLNPIENPDLKLAIVMLIVPFFVNALMFWVVDNFLMRKGKTKAKLEERGANQDSRN

--------------------------------------------------------------
>63011_63011_3_PBRM1-TMEM110_PBRM1_chr3_52584437_ENST00000356770_TMEM110_chr3_52889460_ENST00000355083_length(transcript)=9102nt_BP=4639nt
TCCATGGGTTCCAAGAGAAGAAGAGCTACCTCCCCTTCCAGCAGTGTCAGCGGGGACTTTGATGATGGGCACCATTCTGTGTCAACACCA
GGCCCAAGCAGGAAAAGGAGGAGACTTTCCAATCTTCCAACTGTAGATCCTATTGCCGTGTGCCATGAACTCTATAATACCATCCGAGAC
TATAAGGATGAACAGGGCAGACTTCTCTGTGAGCTCTTCATTAGGGCACCAAAGCGAAGAAATCAACCAGACTATTATGAAGTGGTTTCT
CAGCCCATTGACTTGATGAAAATCCAACAGAAACTAAAAATGGAAGAGTATGATGATGTTAATTTGCTGACTGCTGACTTCCAGCTTCTT
TTTAACAATGCAAAGTCCTATTATAAGCCAGATTCTCCTGAATATAAAGCCGCTTGCAAACTCTGGGATTTGTACCTTCGAACAAGAAAT
GAGTTTGTTCAGAAAGGAGAAGCAGATGACGAAGATGATGATGAAGATGGGCAAGACAATCAGGGCACAGTGACTGAAGGATCTTCTCCA
GCTTACTTGAAGGAGATCCTGGAGCAGCTTCTTGAAGCCATAGTTGTAGCTACAAATCCATCAGGACGTCTCATTAGCGAACTTTTTCAG
AAACTGCCTTCTAAAGTGCAATATCCAGATTATTATGCAATAATTAAGGAGCCTATAGATCTCAAGACCATTGCCCAGAGGATACAGAAT
GGAAGCTACAAAAGTATTCATGCAATGGCCAAAGATATAGATCTCCTCGCAAAAAATGCCAAAACTTATAATGAGCCTGGCTCTCAAGTA
TTCAAGGATGCAAATTCAATTAAAAAAATATTTTATATGAAAAAGGCTGAAATTGAACATCATGAAATGGCTAAGTCAAGTCTTCGAATG
AGTAATAAAAGAGCAGTACAAGGAGGTCGTTTATCAGCAATTACAATGGCACTTCAATATGGCTCAGAAAGTGAAGAAGATGCTGCTTTA
GCTGCTGCACGCTATGAAGAGGGAGAGTCAGAAGCAGAAAGCATCACTTCCTTTATGGATGTTTCAAATCCTTTTTATCAGCTTTATGAC
ACAGTTAGGAGTTGTCGGAATAACCAAGGGCAGCTAATAGCTGAACCTTTTTACCATTTGCCTTCAAAGAAAAAATACCCTGATTATTAC
CAGCAAATTAAAATGCCCATATCACTACAACAGATCCGAACAAAACTGAAGAATCAAGAATATGAAACTTTAGATCATTTGGAGTGTGAT
CTGAATTTAATGTTTGAAAATGCCAAACGCTATAATGTGCCCAATTCAGCCATCTACAAGCGAGTTCTAAAATTGCAGCAAGTTATGCAG
GCAAAGAAGAAAGAGCTTGCCAGGAGAGACGATATCGAGGACGGAGACAGCATGATCTCTTCAGCCACCTCTGATACTGGTAGTGCCAAA
AGAAAAAGTAAAAAGAACATAAGAAAGCAGCGAATGAAAATCTTATTCAATGTTGTTCTTGAAGCTCGAGAGCCAGGTTCAGGCAGAAGA
CTTTGTGACCTATTTATGGTTAAACCATCCAAAAAGGACTATCCTGATTATTATAAAATCATCTTGGAGCCAATGGACTTGAAAATAATT
GAGCATAACATCCGCAATGACAAATATGCTGGTGAAGAGGGAATGATAGAAGACATGAAGCTGATGTTCCGGAATGCCAGGCACTATAAT
GAGGAGGGCTCCCAGGTTTATAATGATGCACATATCCTGGAGAAGTTACTCAAGGAGAAAAGGAAAGAGCTGGGCCCACTGCCTGATGAT
GATGACATGGCTTCTCCCAAACTCAAGCTGAGTAGGAAGAGTGGCATTTCTCCTAAAAAATCAAAATACATGACTCCAATGCAGCAGAAA
CTAAATGAGGTCTATGAAGCTGTAAAGAACTATACTGATAAGAGGGGTCGCCGCCTCAGTGCCATATTTCTGAGGCTTCCCTCTAGATCT
GAGTTGCCTGACTACTATCTGACTATTAAAAAGCCCATGGACATGGAAAAAATTCGAAGTCACATGATGGCCAACAAGTACCAAGATATT
GACTCTATGGTTGAGGACTTTGTCATGATGTTTAATAATGCCTGTACATACAATGAGCCGGAGTCTTTGATCTACAAAGATGCTCTTGTT
CTACACAAAGTCCTGCTTGAAACACGCAGAGACCTGGAGGGAGATGAGGACTCTCATGTCCCAAATGTGACTTTGCTGATTCAAGAGCTT
ATCCACAATCTTTTTGTGTCAGTCATGAGTCATCAGGATGATGAGGGAAGATGCTACAGCGATTCTTTAGCAGAAATTCCTGCTGTGGAT
CCCAACTTTCCTAACAAACCACCCCTTACATTTGACATAATTAGGAAGAATGTTGAAAATAATCGCTACCGTCGGCTTGATTTATTTCAA
GAGCATATGTTTGAAGTATTGGAACGAGCAAGAAGGATGAATCGGACAGATTCAGAAATATATGAAGATGCAGTAGAACTTCAGCAGTTT
TTTATTAAAATTCGTGATGAACTCTGCAAAAATGGAGAGATTCTTCTTTCACCGGCACTCAGCTATACCACAAAACATTTGCATAATGAT
GTGGAGAAAGAGAGAAAGGAAAAATTGCCAAAAGAAATAGAGGAAGATAAACTAAAACGAGAAGAAGAAAAAAGAGAAGCTGAAAAGAGT
GAAGATTCCTCTGGTGCTGCAGGCCTCTCAGGCTTACATCGCACATACAGCCAGGACTGTAGCTTTAAAAACAGCATGTACCATGTTGGA
GATTACGTCTATGTGGAACCTGCAGAGGCCAACCTACAACCACATATCGTCTGTATTGAAAGACTGTGGGAGGATTCAGCTGGTGAAAAA
TGGTTGTATGGCTGTTGGTTTTACCGACCAAATGAAACATTCCACCTGGCTACACGAAAATTTCTAGAAAAAGAAGTTTTTAAGAGTGAC
TATTACAACAAAGTTCCAGTTAGTAAAATTCTAGGCAAGTGTGTGGTCATGTTTGTCAAGGAATACTTTAAGTTATGCCCAGAAAACTTC
CGAGATGAGGATGTTTTTGTCTGTGAATCACGGTATTCTGCCAAAACCAAATCTTTTAAGAAAATTAAACTGTGGACCATGCCCATCAGC
TCAGTCAGGTTTGTCCCTCGGGATGTGCCTCTGCCTGTGGTTCGCGTGGCCTCTGTATTTGCAAATGCAGATAAAGGTGATGATGAGAAG
AATACAGACAACTCAGAGGACAGTCGAGCTGAAGACAATTTTAACTTGGAAAAGGAAAAAGAAGATGTCCCTGTGGAAATGTCCAATGGT
GAACCAGGTTGCCACTACTTTGAGCAGCTCCATTACAATGACATGTGGCTGAAGGTTGGCGACTGTGTCTTCATCAAGTCCCATGGCCTG
GTGCGTCCTCGTGTGGGCAGAATTGAAAAAGTATGGGTTCGAGATGGAGCTGCATATTTTTATGGCCCCATCTTCATTCACCCAGAAGAA
ACAGAGCATGAGCCCACAAAAATGTTCTACAAAAAAGAAGTATTTCTGAGTAATCTGGAAGAAACCTGCCCCATGACATGTATTCTCGGA
AAGTGTGCTGTGTTGTCATTCAAGGACTTCCTCTCCTGCAGGCCAACTGAAATACCAGAAAATGACATTCTGCTTTGTGAGAGCCGCTAC
AATGAGAGCGACAAGCAGATGAAGAAATTCAAAGGATTGAAGAGGTTTTCACTCTCTGCTAAAGTGGTAGATGATGAAATTTACTACTTC
AGAAAACCAATTGTTCCTCAGAAGGAGCCATCACCTTTGCTGGAAAAGAAGATCCAGTTGCTAGAAGCTAAATTTGCCGAGTTAGAAGGT
GGAGATGATGATATTGAAGAGATGGGAGAAGAAGATAGTGAGGTCATTGAACCTCCTTCTCTACCTCAGCTTCAGACCCCCCTGGCCAGT
GAGCTGGACCTCATGCCCTACACACCCCCACAGTCTACCCCAAAGTCTGCCAAAGGCAGTGCAAAGAAGGAAGGCTCCAAACGGAAAATC
AACATGAGTGGCTACATCCTGTTCAGCAGTGAGATGAGGGCTGTGATTAAGGCCCAACACCCAGACTACTCTTTCGGGGAGCTCAGCCGC
CTGGTGGGGACAGAATGGAGAAATCTTGAGACAGCCAAGAAAGCAGAATATGAAGGCATGATGGGTGGCTATCCGCCAGGCCTTCCACCT
TTGCAGGGCCCAGTTGATGGCCTTGTTAGCATGGGCAGCATGCAGCCACTTCACCCTGGGGGGCCTCCACCCCACCATCTTCCGCCAGGT
GTGCCTGGCCTCCCGGGCATCCCACCACCGGGTGTGATGAACCAAGGAGTGGCCCCTATGGTAGGGACTCCAGCACCAGGTGGAAGTCCA
TATGGACAACAGGTGGGAGTTTTGGGGCCTCCAGGGCAGCAGGCACCACCTCCATATCCCGGCCCACATCCAGCTGGACCCCCTGTCATA
CAGCAGCCAACAACACCCATGTTTGTAGCTCCCCCACCAAAGACCCAGCGGCTTCTTCACTCAGAGGCCTACCTGAAATACATTGAAGGA
CTCAGTGCGGAGTCCAACAGCATTAGCAAGTGGGATCAGACACTGGCAGTCAAACGCTTCAGAGAACCAAAGCATGAAAGACGTCCGTGG
AGGATATGGTTTTTAGACACTTCCAAACAAGCCATAGGAATGCTGTTCATCCACTTTGCAAATGTATACCTAGCAGATCTCACTGAAGAG
GACCCTTGTTCACTGTACCTCATCAACTTCCTCCTGGACGCCACTGTGGGCATGCTGCTCATCTACGTGGGGGTGCGCGCCGTCAGCGTC
CTGGTAGAGTGGCAGCAGTGGGAGTCCCTGCGCTTCGGCGAATATGGAGACCCTCTGCAGTGTGGAGCCTGGGTCGGGCAGTGCGCTCTT
TACATCGTGATCATGATTTTTGAAAAGTCTGTCGTCTTCATCGTCCTCCTAATACTTCAGTGGAAAAAGGTGGCCCTGTTGAATCCCATT
GAAAACCCAGACTTGAAGCTGGCCATCGTCATGCTGATCGTCCCCTTCTTTGTCAACGCTTTGATGTTTTGGGTAGTGGACAATTTCCTC
ATGAGAAAGGGGAAGACGAAAGCTAAGCTAGAAGAAAGGGGAGCCAACCAGGACTCGAGGAATGGGAGCAAGGTCCGCTACCGGAGGGCC
GCATCCCACGAGGAGTCTGAGTCTGAGATCCTGATCTCAGCGGATGATGAGATGGAGGAGTCCGACGTGGAGGAGGACCTCCGCAGACTG
ACCCCCCTCAAGCCTGTGAAGAAAAAGAAGCACCGCTTTGGGCTACCCGTATGACACATTCCCATGCTGGGGGTGACGGGAGGGCCCCGC
CAGCCGCTGGTGTGCAGAGGTCATCCCGCAGCATCGTTCCTTACCCTCTCTCTGCCCTTCCTTTCTACCTCTGCTCCTCTTGCTGTCTCT
GCCCGCTCTCGCCTGCCCCCAGACTACTGTGACTTAAAAAGAGGGAAGAGGAGCCAGCGCCCGAGGGGGCCACTGGCGGCTGGAGGTCCC
CATTCAGTTGCACTACAAACACTGACCAAATATGCAAGGAAGGAGCTGTGTTTGTTTGTTGTCGTCCCAGACAGTGTTGTGAGGGACCTG
AGGCCCTGCCCCGTGTCCGACCACCGAGTGGCAAGGTGGAAGGAAGCACAGGCACACAGACCGTGGGTGGGTCTCCTCACCGTGGCTGTG
GGCAGTGCGAACACATAACACCCTCGGGCTAAAAGTGACTCGTTGACCAAGTTGGAACCGGAATGCTTTCTTACTCAAAATGGCTTTTGT
AACTATTGATTTCTGAAGCTGGTTTTATGAGTTGTGACAGTGTTACCAGGTTGGGGGTATGTGTTTATTTCCTACAAAGTACTTACGGGA
CTAATGGGCAAAACAGAGATTTTTAAGTCTTCCGTATGCTGTTTGACTTTTATATTTTTAAGTTATATTTTCATACTATTGTATTTAAAA
ACTCTTTTTAGTCCCCAAAGAAATGGGTTTATTTGCCTTTCATGGGGTGTGGGCTGGCAGGAGGAAAAATCGGGAGTTTTTTATTTGGAA
TATTATTAGATGATGCCCTATGATAAGATGAGACAAATGATGGGGAGGGAAGGAGGATGGCCCTTCTCTAGAATCAGCAAACCCAATGGT
TCTGTGAAGGTCAGACCCAAGCTTGGAGCAGCTGGTCTGGATGCAGATCCAGGAGCTGCAGAGTGTGGAACAGGAAAGGCTCTGCCCAGG
GCCCATGAGCTCTAGCATTCCTGCTGGCAGATTAGAGATCTTAGTTAAATTTGACCAAGAAAGGAGCTTAGCTAAGAGGTCTTTGTTTCC
AGAGGACCCAAGACTACCAGACTCCTGTGCAGTCTGCCTGTCTGCAGAGCCTCCAATCACGGTTTAAAGTGGTCTTGGCCTCCCAGCCCC
CACTGCTGCAGCCTTCAGAGCCAGCCTCTGGACTCAGCGCCAGGAGCCTCCTCTCCTGCTGCCCTGGTACCTGTCATCCTAGTGTCACCT
ATTTGTTTTGCACAGCATTCTGGAGAACATGTGCCTCACAAAGTGATCCTGTTTTTCTCACCCTCCAAAGCTGAGGTGGCTAAGGGAGGC
AGGGGTGAGAGAGCTCACTCTCTAAACCACAGGCAGGGCAAGGTGCTTCTAGGCCGTGTCCCCTCCCTGGGGAATGGTCACTACTCCTCA
GCATGGCCACAGGCCCCTGTGGTTTTGGGAGTTTGCTGAGTGACTGTGGAATGGGCTGACCCCAGCCGTTTCCCTGCTGTGGAAACAGCA
AGGTAGGGGCACTGCTTGGTGGTTTGTCAAGCTCAGAGGCAGCCACGGATGGTTAGGAACAGGAAGCCACACTGCTAAGGTGTGATGAGC
TAGAAGGGAGACATCCTGGACTTCAAGTGAGACAAGTGCAGAGGAGGCCACTCCACTTAGGACCTTCCTTTTAGACCTGCATGAGCACGT
GTTTCACTTAAGCACATTGGGTCCGAATTGGGCGCATGAACCCAGCTGTTAAACCAGGTACCCTGGGACTGCCCTCTGCCTCTCAGAGCC
CTACCTGTCCTGGACTTGAAGGCGAGCATCAGGCAGGCCTTCTCAGCCCATCTTCCACCAGGAGTGCAGAGCCAGGGTGCTGAGAGGAGC
AGGGACTGTAACTACAGTAGGAGGCAACTTTGCTGGTGTCATTCCTGCTCGGATTGACTTTGTGCTCCCTCCCATCCACAGCTATGGTAG
CCAGTATTTCCCCAGCAGCTCTCTAGTGGGGAAGAGTGGCTAGAACCAGGCCATTCTCAGTCGAATTTAGGAAGACCAAGACTCATGTTC
CTGACAGGACGGTCATTCCCTCATGGCATCACTGACTCAGTTCTAATTCCTCCCCTCCTGTTTCATTTTGGTTTGAACAACCTGTGCCTG
CAGCTGTTTCTTCCACCTTCCTGGAGCTCACAATTGGAGCTTCATGTTCAGTCTTGAGCTCCTAATGTTTCCAGACAGGGCAGGGGATAG
GAGAGCCATAATCTATGAAAGCTGTGAAACAAACCCTGGGTTATATAGATCTCAGATGGTCTCATCTGAAGGCTTTGCCCACTTCCCAGT
GAGCAGAGGGTTTGGGGAACAAAGAGGTAGCTGAAGAGTGGTGGTTTTTCCCTGTATCCTGATTTTCAGAAAGGGCTTTAGTCTCTGAGC
TGTGGCTAGTAGCTGGCTGGCTGACCAGGGGACGGGGGTCTAATAGGGTGTCTGACCATAGGACACCTCTCGTGTTTGGCCTTCCCTTTC
TTGTGTGTTTGTGTGTGTGTGTGCACGTGCACGTGCACACACATGTACACACACAAATCTGTATCCCCAGGAGTGCCTCCTGCAGTCACT
GGGGGCTCTTCCGTGGTGCACCATCCCATGAGAGCAGATCAGAGGGCTGTGGTCAGGACTTCCTCCCGAGCTGCCCTCCCTCCCTGGGAT
GAGTTTCCTCTCCACCTGCTCCAAGGTGCCTTACGAGGTGCAGCTCTTCACCTGGCCACATGGCATCCATCACCGTGTTGAGAAATGGTG
GGACGTTGGCTGGATATTGTGTGCTATGAATCTGATTTGTCCAAATCTGGACCTCAGCCAAGCCACCTGTGGTGGAACCTTGCAAGTCAA
GGTCATGAACAAATTTCTTGTAACTATTGGAAATAAACTAATGAGGTAGAACTGTCATATCCAAATGGAAGAGGTGGTTGGTACTGTTAC
TTCCTTTTGCTGTCAGAGGGTTGTTGACAATGGCAAGGGGGGATGTTAGTGAGATCCAGGTGGTGGTGGCTTCTTGGTCCACTCAGCTTG
CACACATGCAAGAGGAGGGTCTGTGGCCCCTCAGCCGTGCTGGTGGCCTCCTTCCTCAAGCTTTAACTTGTGCCCTCCCTGGCAACAGGG
AGTCATGGGTTAATGTCACCTGTCATGCCTCTTTCTTCAGGGAAAATATTAAAAGGCTCAAATCCAAGCTGTGACTTCCCTTAGACAGTG
TAAGCCTGTAGGGTGCAGCCCCAAGTTTATGTCCAAAGGCTGCCTCAGAACCCTGGAGGGAGCAGCGCCCAGCTGGCAGCTCACTCTGCC
CTTGCAGTTCACTGGCCTTTTCGCAGCCAGGCTAAGATAGGCAGTGCAAGGAGCTTCCCACTGGCCAGAGCAGCTGCCTTGTAGAATGTG
GGGCTGGCTTTTAGAAGTTTCACACGCTTGCAGCTAAGAGTGCAGAGCTCTCTGTTTTACTTCGTGAAACATTAGCAGCTCTGAGGGGCT
TGGCTTTTGGTAAGGGACTTATGGTCTGACTTGCCACAAGCACCTTGAGCTCCTGGGTTGGTTGGTGGTTGGTTGGTTGGGTTGTTTTAA
ATTTGATTTTTCTTTTCCTGAAGTTTGTTAGAAGTCAGACCTATGCAAGGAAAACCATGGCCCACTTCAGCAGCCATCCAGTGGGGGTGC
TTAATCGGTGGTGGTAGGATTCATGGAAACGTTTTTTTGAAATGAAAGAGAAGATGATGTACTTACATTGTAAAATGGTTTACAATAAAG

>63011_63011_3_PBRM1-TMEM110_PBRM1_chr3_52584437_ENST00000356770_TMEM110_chr3_52889460_ENST00000355083_length(amino acids)=1786AA_BP=1543
MGSKRRRATSPSSSVSGDFDDGHHSVSTPGPSRKRRRLSNLPTVDPIAVCHELYNTIRDYKDEQGRLLCELFIRAPKRRNQPDYYEVVSQ
PIDLMKIQQKLKMEEYDDVNLLTADFQLLFNNAKSYYKPDSPEYKAACKLWDLYLRTRNEFVQKGEADDEDDDEDGQDNQGTVTEGSSPA
YLKEILEQLLEAIVVATNPSGRLISELFQKLPSKVQYPDYYAIIKEPIDLKTIAQRIQNGSYKSIHAMAKDIDLLAKNAKTYNEPGSQVF
KDANSIKKIFYMKKAEIEHHEMAKSSLRMSNKRAVQGGRLSAITMALQYGSESEEDAALAAARYEEGESEAESITSFMDVSNPFYQLYDT
VRSCRNNQGQLIAEPFYHLPSKKKYPDYYQQIKMPISLQQIRTKLKNQEYETLDHLECDLNLMFENAKRYNVPNSAIYKRVLKLQQVMQA
KKKELARRDDIEDGDSMISSATSDTGSAKRKSKKNIRKQRMKILFNVVLEAREPGSGRRLCDLFMVKPSKKDYPDYYKIILEPMDLKIIE
HNIRNDKYAGEEGMIEDMKLMFRNARHYNEEGSQVYNDAHILEKLLKEKRKELGPLPDDDDMASPKLKLSRKSGISPKKSKYMTPMQQKL
NEVYEAVKNYTDKRGRRLSAIFLRLPSRSELPDYYLTIKKPMDMEKIRSHMMANKYQDIDSMVEDFVMMFNNACTYNEPESLIYKDALVL
HKVLLETRRDLEGDEDSHVPNVTLLIQELIHNLFVSVMSHQDDEGRCYSDSLAEIPAVDPNFPNKPPLTFDIIRKNVENNRYRRLDLFQE
HMFEVLERARRMNRTDSEIYEDAVELQQFFIKIRDELCKNGEILLSPALSYTTKHLHNDVEKERKEKLPKEIEEDKLKREEEKREAEKSE
DSSGAAGLSGLHRTYSQDCSFKNSMYHVGDYVYVEPAEANLQPHIVCIERLWEDSAGEKWLYGCWFYRPNETFHLATRKFLEKEVFKSDY
YNKVPVSKILGKCVVMFVKEYFKLCPENFRDEDVFVCESRYSAKTKSFKKIKLWTMPISSVRFVPRDVPLPVVRVASVFANADKGDDEKN
TDNSEDSRAEDNFNLEKEKEDVPVEMSNGEPGCHYFEQLHYNDMWLKVGDCVFIKSHGLVRPRVGRIEKVWVRDGAAYFYGPIFIHPEET
EHEPTKMFYKKEVFLSNLEETCPMTCILGKCAVLSFKDFLSCRPTEIPENDILLCESRYNESDKQMKKFKGLKRFSLSAKVVDDEIYYFR
KPIVPQKEPSPLLEKKIQLLEAKFAELEGGDDDIEEMGEEDSEVIEPPSLPQLQTPLASELDLMPYTPPQSTPKSAKGSAKKEGSKRKIN
MSGYILFSSEMRAVIKAQHPDYSFGELSRLVGTEWRNLETAKKAEYEGMMGGYPPGLPPLQGPVDGLVSMGSMQPLHPGGPPPHHLPPGV
PGLPGIPPPGVMNQGVAPMVGTPAPGGSPYGQQVGVLGPPGQQAPPPYPGPHPAGPPVIQQPTTPMFVAPPPKTQRLLHSEAYLKYIEGL
SAESNSISKWDQTLAVKRFREPKHERRPWRIWFLDTSKQAIGMLFIHFANVYLADLTEEDPCSLYLINFLLDATVGMLLIYVGVRAVSVL
VEWQQWESLRFGEYGDPLQCGAWVGQCALYIVIMIFEKSVVFIVLLILQWKKVALLNPIENPDLKLAIVMLIVPFFVNALMFWVVDNFLM

--------------------------------------------------------------
>63011_63011_4_PBRM1-TMEM110_PBRM1_chr3_52584437_ENST00000409057_TMEM110_chr3_52889460_ENST00000355083_length(transcript)=9198nt_BP=4735nt
TCCATGGGTTCCAAGAGAAGAAGAGCTACCTCCCCTTCCAGCAGTGTCAGCGGGGACTTTGATGATGGGCACCATTCTGTGTCAACACCA
GGCCCAAGCAGGAAAAGGAGGAGACTTTCCAATCTTCCAACTGTAGATCCTATTGCCGTGTGCCATGAACTCTATAATACCATCCGAGAC
TATAAGGATGAACAGGGCAGACTTCTCTGTGAGCTCTTCATTAGGGCACCAAAGCGAAGAAATCAACCAGACTATTATGAAGTGGTTTCT
CAGCCCATTGACTTGATGAAAATCCAACAGAAACTAAAAATGGAAGAGTATGATGATGTTAATTTGCTGACTGCTGACTTCCAGCTTCTT
TTTAACAATGCAAAGTCCTATTATAAGCCAGATTCTCCTGAATATAAAGCCGCTTGCAAACTCTGGGATTTGTACCTTCGAACAAGAAAT
GAGTTTGTTCAGAAAGGAGAAGCAGATGACGAAGATGATGATGAAGATGGGCAAGACAATCAGGGCACAGTGACTGAAGGATCTTCTCCA
GCTTACTTGAAGGAGATCCTGGAGCAGCTTCTTGAAGCCATAGTTGTAGCTACAAATCCATCAGGACGTCTCATTAGCGAACTTTTTCAG
AAACTGCCTTCTAAAGTGCAATATCCAGATTATTATGCAATAATTAAGGAGCCTATAGATCTCAAGACCATTGCCCAGAGGATACAGAAT
GGAAGCTACAAAAGTATTCATGCAATGGCCAAAGATATAGATCTCCTCGCAAAAAATGCCAAAACTTATAATGAGCCTGGCTCTCAAGTA
TTCAAGGATGCAAATTCAATTAAAAAAATATTTTATATGAAAAAGGCTGAAATTGAACATCATGAAATGGCTAAGTCAAGTCTTCGAATG
AGGACTCCATCCAACTTGGCTGCAGCCAGACTGACAGGTCCTTCACACAGTAAAGGCAGCCTTGGTGAAGAGAGAAATCCCACTAGCAAG
TATTACCGTAATAAAAGAGCAGTACAAGGAGGTCGTTTATCAGCAATTACAATGGCACTTCAATATGGCTCAGAAAGTGAAGAAGATGCT
GCTTTAGCTGCTGCACGCTATGAAGAGGGAGAGTCAGAAGCAGAAAGCATCACTTCCTTTATGGATGTTTCAAATCCTTTTTATCAGCTT
TATGACACAGTTAGGAGTTGTCGGAATAACCAAGGGCAGCTAATAGCTGAACCTTTTTACCATTTGCCTTCAAAGAAAAAATACCCTGAT
TATTACCAGCAAATTAAAATGCCCATATCACTACAACAGATCCGAACAAAACTGAAGAATCAAGAATATGAAACTTTAGATCATTTGGAG
TGTGATCTGAATTTAATGTTTGAAAATGCCAAACGCTATAATGTGCCCAATTCAGCCATCTACAAGCGAGTTCTAAAATTGCAGCAAGTT
ATGCAGGCAAAGAAGAAAGAGCTTGCCAGGAGAGACGATATCGAGGACGGAGACAGCATGATCTCTTCAGCCACCTCTGATACTGGTAGT
GCCAAAAGAAAAAGTAAAAAGAACATAAGAAAGCAGCGAATGAAAATCTTATTCAATGTTGTTCTTGAAGCTCGAGAGCCAGGTTCAGGC
AGAAGACTTTGTGACCTATTTATGGTTAAACCATCCAAAAAGGACTATCCTGATTATTATAAAATCATCTTGGAGCCAATGGACTTGAAA
ATAATTGAGCATAACATCCGCAATGACAAATATGCTGGTGAAGAGGGAATGATAGAAGACATGAAGCTGATGTTCCGGAATGCCAGGCAC
TATAATGAGGAGGGCTCCCAGGTTTATAATGATGCACATATCCTGGAGAAGTTACTCAAGGAGAAAAGGAAAGAGCTGGGCCCACTGCCT
GATGATGATGACATGGCTTCTCCCAAACTCAAGCTGAGTAGGAAGAGTGGCATTTCTCCTAAAAAATCAAAATACATGACTCCAATGCAG
CAGAAACTAAATGAGGTCTATGAAGCTGTAAAGAACTATACTGATAAGAGGGGTCGCCGCCTCAGTGCCATATTTCTGAGGCTTCCCTCT
AGATCTGAGTTGCCTGACTACTATCTGACTATTAAAAAGCCCATGGACATGGAAAAAATTCGAAGTCACATGATGGCCAACAAGTACCAA
GATATTGACTCTATGGTTGAGGACTTTGTCATGATGTTTAATAATGCCTGTACATACAATGAGCCGGAGTCTTTGATCTACAAAGATGCT
CTTGTTCTACACAAAGTCCTGCTTGAAACACGCAGAGACCTGGAGGGAGATGAGGACTCTCATGTCCCAAATGTGACTTTGCTGATTCAA
GAGCTTATCCACAATCTTTTTGTGTCAGTCATGAGTCATCAGGATGATGAGGGAAGATGCTACAGCGATTCTTTAGCAGAAATTCCTGCT
GTGGATCCCAACTTTCCTAACAAACCACCCCTTACATTTGACATAATTAGGAAGAATGTTGAAAATAATCGCTACCGTCGGCTTGATTTA
TTTCAAGAGCATATGTTTGAAGTATTGGAACGAGCAAGAAGGATGAATCGGACAGATTCAGAAATATATGAAGATGCAGTAGAACTTCAG
CAGTTTTTTATTAAAATTCGTGATGAACTCTGCAAAAATGGAGAGATTCTTCTTTCACCGGCACTCAGCTATACCACAAAACATTTGCAT
AATGATGTGGAGAAAGAGAGAAAGGAAAAATTGCCAAAAGAAATAGAGGAAGATAAACTAAAACGAGAAGAAGAAAAAAGAGAAGCTGAA
AAGAGTGAAGATTCCTCTGGTGCTGCAGGCCTCTCAGGCTTACATCGCACATACAGCCAGGACTGTAGCTTTAAAAACAGCATGTACCAT
GTTGGAGATTACGTCTATGTGGAACCTGCAGAGGCCAACCTACAACCACATATCGTCTGTATTGAAAGACTGTGGGAGGATTCAGCTGGT
GAAAAATGGTTGTATGGCTGTTGGTTTTACCGACCAAATGAAACATTCCACCTGGCTACACGAAAATTTCTAGAAAAAGAAGTTTTTAAG
AGTGACTATTACAACAAAGTTCCAGTTAGTAAAATTCTAGGCAAGTGTGTGGTCATGTTTGTCAAGGAATACTTTAAGTTATGCCCAGAA
AACTTCCGAGATGAGGATGTTTTTGTCTGTGAATCACGGTATTCTGCCAAAACCAAATCTTTTAAGAAAATTAAACTGTGGACCATGCCC
ATCAGCTCAGTCAGGTTTGTCCCTCGGGATGTGCCTCTGCCTGTGGTTCGCGTGGCCTCTGTATTTGCAAATGCAGATAAAGGTGATGAT
GAGAAGAATACAGACAACTCAGAGGACAGTCGAGCTGAAGACAATTTTAACTTGGAAAAGGAAAAAGAAGATGTCCCTGTGGAAATGTCC
AATGGTGAACCAGGTTGCCACTACTTTGAGCAGCTCCATTACAATGACATGTGGCTGAAGGTTGGCGACTGTGTCTTCATCAAGTCCCAT
GGCCTGGTGCGTCCTCGTGTGGGCAGAATTGAAAAAGTATGGGTTCGAGATGGAGCTGCATATTTTTATGGCCCCATCTTCATTCACCCA
GAAGAAACAGAGCATGAGCCCACAAAAATGTTCTACAAAAAAGAAGTATTTCTGAGTAATCTGGAAGAAACCTGCCCCATGACATGTATT
CTCGGAAAGTGTGCTGTGTTGTCATTCAAGGACTTCCTCTCCTGCAGGCCAACTGAAATACCAGAAAATGACATTCTGCTTTGTGAGAGC
CGCTACAATGAGAGCGACAAGCAGATGAAGAAATTCAAAGGATTGAAGAGGTTTTCACTCTCTGCTAAAGTGGTAGATGATGAAATTTAC
TACTTCAGAAAACCAATTGTTCCTCAGAAGGAGCCATCACCTTTGCTGGAAAAGAAGATCCAGTTGCTAGAAGCTAAATTTGCCGAGTTA
GAAGGTGGAGATGATGATATTGAAGAGATGGGAGAAGAAGATAGTGAGGTCATTGAACCTCCTTCTCTACCTCAGCTTCAGACCCCCCTG
GCCAGTGAGCTGGACCTCATGCCCTACACACCCCCACAGTCTACCCCAAAGTCTGCCAAAGGCAGTGCAAAGAAGGAAGGCTCCAAACGG
AAAATCAACATGAGTGGCTACATCCTGTTCAGCAGTGAGATGAGGGCTGTGATTAAGGCCCAACACCCAGACTACTCTTTCGGGGAGCTC
AGCCGCCTGGTGGGGACAGAATGGAGAAATCTTGAGACAGCCAAGAAAGCAGAATATGAAGGCATGATGGGTGGCTATCCGCCAGGCCTT
CCACCTTTGCAGGGCCCAGTTGATGGCCTTGTTAGCATGGGCAGCATGCAGCCACTTCACCCTGGGGGGCCTCCACCCCACCATCTTCCG
CCAGGTGTGCCTGGCCTCCCGGGCATCCCACCACCGGGTGTGATGAACCAAGGAGTGGCCCCTATGGTAGGGACTCCAGCACCAGGTGGA
AGTCCATATGGACAACAGGTGGGAGTTTTGGGGCCTCCAGGGCAGCAGGCACCACCTCCATATCCCGGCCCACATCCAGCTGGACCCCCT
GTCATACAGCAGCCAACAACACCCATGTTTGTAGCTCCCCCACCAAAGACCCAGCGGCTTCTTCACTCAGAGGCCTACCTGAAATACATT
GAAGGACTCAGTGCGGAGTCCAACAGCATTAGCAAGTGGGATCAGACACTGGCAGTCAAACGCTTCAGAGAACCAAAGCATGAAAGACGT
CCGTGGAGGATATGGTTTTTAGACACTTCCAAACAAGCCATAGGAATGCTGTTCATCCACTTTGCAAATGTATACCTAGCAGATCTCACT
GAAGAGGACCCTTGTTCACTGTACCTCATCAACTTCCTCCTGGACGCCACTGTGGGCATGCTGCTCATCTACGTGGGGGTGCGCGCCGTC
AGCGTCCTGGTAGAGTGGCAGCAGTGGGAGTCCCTGCGCTTCGGCGAATATGGAGACCCTCTGCAGTGTGGAGCCTGGGTCGGGCAGTGC
GCTCTTTACATCGTGATCATGATTTTTGAAAAGTCTGTCGTCTTCATCGTCCTCCTAATACTTCAGTGGAAAAAGGTGGCCCTGTTGAAT
CCCATTGAAAACCCAGACTTGAAGCTGGCCATCGTCATGCTGATCGTCCCCTTCTTTGTCAACGCTTTGATGTTTTGGGTAGTGGACAAT
TTCCTCATGAGAAAGGGGAAGACGAAAGCTAAGCTAGAAGAAAGGGGAGCCAACCAGGACTCGAGGAATGGGAGCAAGGTCCGCTACCGG
AGGGCCGCATCCCACGAGGAGTCTGAGTCTGAGATCCTGATCTCAGCGGATGATGAGATGGAGGAGTCCGACGTGGAGGAGGACCTCCGC
AGACTGACCCCCCTCAAGCCTGTGAAGAAAAAGAAGCACCGCTTTGGGCTACCCGTATGACACATTCCCATGCTGGGGGTGACGGGAGGG
CCCCGCCAGCCGCTGGTGTGCAGAGGTCATCCCGCAGCATCGTTCCTTACCCTCTCTCTGCCCTTCCTTTCTACCTCTGCTCCTCTTGCT
GTCTCTGCCCGCTCTCGCCTGCCCCCAGACTACTGTGACTTAAAAAGAGGGAAGAGGAGCCAGCGCCCGAGGGGGCCACTGGCGGCTGGA
GGTCCCCATTCAGTTGCACTACAAACACTGACCAAATATGCAAGGAAGGAGCTGTGTTTGTTTGTTGTCGTCCCAGACAGTGTTGTGAGG
GACCTGAGGCCCTGCCCCGTGTCCGACCACCGAGTGGCAAGGTGGAAGGAAGCACAGGCACACAGACCGTGGGTGGGTCTCCTCACCGTG
GCTGTGGGCAGTGCGAACACATAACACCCTCGGGCTAAAAGTGACTCGTTGACCAAGTTGGAACCGGAATGCTTTCTTACTCAAAATGGC
TTTTGTAACTATTGATTTCTGAAGCTGGTTTTATGAGTTGTGACAGTGTTACCAGGTTGGGGGTATGTGTTTATTTCCTACAAAGTACTT
ACGGGACTAATGGGCAAAACAGAGATTTTTAAGTCTTCCGTATGCTGTTTGACTTTTATATTTTTAAGTTATATTTTCATACTATTGTAT
TTAAAAACTCTTTTTAGTCCCCAAAGAAATGGGTTTATTTGCCTTTCATGGGGTGTGGGCTGGCAGGAGGAAAAATCGGGAGTTTTTTAT
TTGGAATATTATTAGATGATGCCCTATGATAAGATGAGACAAATGATGGGGAGGGAAGGAGGATGGCCCTTCTCTAGAATCAGCAAACCC
AATGGTTCTGTGAAGGTCAGACCCAAGCTTGGAGCAGCTGGTCTGGATGCAGATCCAGGAGCTGCAGAGTGTGGAACAGGAAAGGCTCTG
CCCAGGGCCCATGAGCTCTAGCATTCCTGCTGGCAGATTAGAGATCTTAGTTAAATTTGACCAAGAAAGGAGCTTAGCTAAGAGGTCTTT
GTTTCCAGAGGACCCAAGACTACCAGACTCCTGTGCAGTCTGCCTGTCTGCAGAGCCTCCAATCACGGTTTAAAGTGGTCTTGGCCTCCC
AGCCCCCACTGCTGCAGCCTTCAGAGCCAGCCTCTGGACTCAGCGCCAGGAGCCTCCTCTCCTGCTGCCCTGGTACCTGTCATCCTAGTG
TCACCTATTTGTTTTGCACAGCATTCTGGAGAACATGTGCCTCACAAAGTGATCCTGTTTTTCTCACCCTCCAAAGCTGAGGTGGCTAAG
GGAGGCAGGGGTGAGAGAGCTCACTCTCTAAACCACAGGCAGGGCAAGGTGCTTCTAGGCCGTGTCCCCTCCCTGGGGAATGGTCACTAC
TCCTCAGCATGGCCACAGGCCCCTGTGGTTTTGGGAGTTTGCTGAGTGACTGTGGAATGGGCTGACCCCAGCCGTTTCCCTGCTGTGGAA
ACAGCAAGGTAGGGGCACTGCTTGGTGGTTTGTCAAGCTCAGAGGCAGCCACGGATGGTTAGGAACAGGAAGCCACACTGCTAAGGTGTG
ATGAGCTAGAAGGGAGACATCCTGGACTTCAAGTGAGACAAGTGCAGAGGAGGCCACTCCACTTAGGACCTTCCTTTTAGACCTGCATGA
GCACGTGTTTCACTTAAGCACATTGGGTCCGAATTGGGCGCATGAACCCAGCTGTTAAACCAGGTACCCTGGGACTGCCCTCTGCCTCTC
AGAGCCCTACCTGTCCTGGACTTGAAGGCGAGCATCAGGCAGGCCTTCTCAGCCCATCTTCCACCAGGAGTGCAGAGCCAGGGTGCTGAG
AGGAGCAGGGACTGTAACTACAGTAGGAGGCAACTTTGCTGGTGTCATTCCTGCTCGGATTGACTTTGTGCTCCCTCCCATCCACAGCTA
TGGTAGCCAGTATTTCCCCAGCAGCTCTCTAGTGGGGAAGAGTGGCTAGAACCAGGCCATTCTCAGTCGAATTTAGGAAGACCAAGACTC
ATGTTCCTGACAGGACGGTCATTCCCTCATGGCATCACTGACTCAGTTCTAATTCCTCCCCTCCTGTTTCATTTTGGTTTGAACAACCTG
TGCCTGCAGCTGTTTCTTCCACCTTCCTGGAGCTCACAATTGGAGCTTCATGTTCAGTCTTGAGCTCCTAATGTTTCCAGACAGGGCAGG
GGATAGGAGAGCCATAATCTATGAAAGCTGTGAAACAAACCCTGGGTTATATAGATCTCAGATGGTCTCATCTGAAGGCTTTGCCCACTT
CCCAGTGAGCAGAGGGTTTGGGGAACAAAGAGGTAGCTGAAGAGTGGTGGTTTTTCCCTGTATCCTGATTTTCAGAAAGGGCTTTAGTCT
CTGAGCTGTGGCTAGTAGCTGGCTGGCTGACCAGGGGACGGGGGTCTAATAGGGTGTCTGACCATAGGACACCTCTCGTGTTTGGCCTTC
CCTTTCTTGTGTGTTTGTGTGTGTGTGTGCACGTGCACGTGCACACACATGTACACACACAAATCTGTATCCCCAGGAGTGCCTCCTGCA
GTCACTGGGGGCTCTTCCGTGGTGCACCATCCCATGAGAGCAGATCAGAGGGCTGTGGTCAGGACTTCCTCCCGAGCTGCCCTCCCTCCC
TGGGATGAGTTTCCTCTCCACCTGCTCCAAGGTGCCTTACGAGGTGCAGCTCTTCACCTGGCCACATGGCATCCATCACCGTGTTGAGAA
ATGGTGGGACGTTGGCTGGATATTGTGTGCTATGAATCTGATTTGTCCAAATCTGGACCTCAGCCAAGCCACCTGTGGTGGAACCTTGCA
AGTCAAGGTCATGAACAAATTTCTTGTAACTATTGGAAATAAACTAATGAGGTAGAACTGTCATATCCAAATGGAAGAGGTGGTTGGTAC
TGTTACTTCCTTTTGCTGTCAGAGGGTTGTTGACAATGGCAAGGGGGGATGTTAGTGAGATCCAGGTGGTGGTGGCTTCTTGGTCCACTC
AGCTTGCACACATGCAAGAGGAGGGTCTGTGGCCCCTCAGCCGTGCTGGTGGCCTCCTTCCTCAAGCTTTAACTTGTGCCCTCCCTGGCA
ACAGGGAGTCATGGGTTAATGTCACCTGTCATGCCTCTTTCTTCAGGGAAAATATTAAAAGGCTCAAATCCAAGCTGTGACTTCCCTTAG
ACAGTGTAAGCCTGTAGGGTGCAGCCCCAAGTTTATGTCCAAAGGCTGCCTCAGAACCCTGGAGGGAGCAGCGCCCAGCTGGCAGCTCAC
TCTGCCCTTGCAGTTCACTGGCCTTTTCGCAGCCAGGCTAAGATAGGCAGTGCAAGGAGCTTCCCACTGGCCAGAGCAGCTGCCTTGTAG
AATGTGGGGCTGGCTTTTAGAAGTTTCACACGCTTGCAGCTAAGAGTGCAGAGCTCTCTGTTTTACTTCGTGAAACATTAGCAGCTCTGA
GGGGCTTGGCTTTTGGTAAGGGACTTATGGTCTGACTTGCCACAAGCACCTTGAGCTCCTGGGTTGGTTGGTGGTTGGTTGGTTGGGTTG
TTTTAAATTTGATTTTTCTTTTCCTGAAGTTTGTTAGAAGTCAGACCTATGCAAGGAAAACCATGGCCCACTTCAGCAGCCATCCAGTGG
GGGTGCTTAATCGGTGGTGGTAGGATTCATGGAAACGTTTTTTTGAAATGAAAGAGAAGATGATGTACTTACATTGTAAAATGGTTTACA

>63011_63011_4_PBRM1-TMEM110_PBRM1_chr3_52584437_ENST00000409057_TMEM110_chr3_52889460_ENST00000355083_length(amino acids)=1818AA_BP=1575
MGSKRRRATSPSSSVSGDFDDGHHSVSTPGPSRKRRRLSNLPTVDPIAVCHELYNTIRDYKDEQGRLLCELFIRAPKRRNQPDYYEVVSQ
PIDLMKIQQKLKMEEYDDVNLLTADFQLLFNNAKSYYKPDSPEYKAACKLWDLYLRTRNEFVQKGEADDEDDDEDGQDNQGTVTEGSSPA
YLKEILEQLLEAIVVATNPSGRLISELFQKLPSKVQYPDYYAIIKEPIDLKTIAQRIQNGSYKSIHAMAKDIDLLAKNAKTYNEPGSQVF
KDANSIKKIFYMKKAEIEHHEMAKSSLRMRTPSNLAAARLTGPSHSKGSLGEERNPTSKYYRNKRAVQGGRLSAITMALQYGSESEEDAA
LAAARYEEGESEAESITSFMDVSNPFYQLYDTVRSCRNNQGQLIAEPFYHLPSKKKYPDYYQQIKMPISLQQIRTKLKNQEYETLDHLEC
DLNLMFENAKRYNVPNSAIYKRVLKLQQVMQAKKKELARRDDIEDGDSMISSATSDTGSAKRKSKKNIRKQRMKILFNVVLEAREPGSGR
RLCDLFMVKPSKKDYPDYYKIILEPMDLKIIEHNIRNDKYAGEEGMIEDMKLMFRNARHYNEEGSQVYNDAHILEKLLKEKRKELGPLPD
DDDMASPKLKLSRKSGISPKKSKYMTPMQQKLNEVYEAVKNYTDKRGRRLSAIFLRLPSRSELPDYYLTIKKPMDMEKIRSHMMANKYQD
IDSMVEDFVMMFNNACTYNEPESLIYKDALVLHKVLLETRRDLEGDEDSHVPNVTLLIQELIHNLFVSVMSHQDDEGRCYSDSLAEIPAV
DPNFPNKPPLTFDIIRKNVENNRYRRLDLFQEHMFEVLERARRMNRTDSEIYEDAVELQQFFIKIRDELCKNGEILLSPALSYTTKHLHN
DVEKERKEKLPKEIEEDKLKREEEKREAEKSEDSSGAAGLSGLHRTYSQDCSFKNSMYHVGDYVYVEPAEANLQPHIVCIERLWEDSAGE
KWLYGCWFYRPNETFHLATRKFLEKEVFKSDYYNKVPVSKILGKCVVMFVKEYFKLCPENFRDEDVFVCESRYSAKTKSFKKIKLWTMPI
SSVRFVPRDVPLPVVRVASVFANADKGDDEKNTDNSEDSRAEDNFNLEKEKEDVPVEMSNGEPGCHYFEQLHYNDMWLKVGDCVFIKSHG
LVRPRVGRIEKVWVRDGAAYFYGPIFIHPEETEHEPTKMFYKKEVFLSNLEETCPMTCILGKCAVLSFKDFLSCRPTEIPENDILLCESR
YNESDKQMKKFKGLKRFSLSAKVVDDEIYYFRKPIVPQKEPSPLLEKKIQLLEAKFAELEGGDDDIEEMGEEDSEVIEPPSLPQLQTPLA
SELDLMPYTPPQSTPKSAKGSAKKEGSKRKINMSGYILFSSEMRAVIKAQHPDYSFGELSRLVGTEWRNLETAKKAEYEGMMGGYPPGLP
PLQGPVDGLVSMGSMQPLHPGGPPPHHLPPGVPGLPGIPPPGVMNQGVAPMVGTPAPGGSPYGQQVGVLGPPGQQAPPPYPGPHPAGPPV
IQQPTTPMFVAPPPKTQRLLHSEAYLKYIEGLSAESNSISKWDQTLAVKRFREPKHERRPWRIWFLDTSKQAIGMLFIHFANVYLADLTE
EDPCSLYLINFLLDATVGMLLIYVGVRAVSVLVEWQQWESLRFGEYGDPLQCGAWVGQCALYIVIMIFEKSVVFIVLLILQWKKVALLNP
IENPDLKLAIVMLIVPFFVNALMFWVVDNFLMRKGKTKAKLEERGANQDSRNGSKVRYRRAASHEESESEILISADDEMEESDVEEDLRR

--------------------------------------------------------------
>63011_63011_5_PBRM1-TMEM110_PBRM1_chr3_52584437_ENST00000409114_TMEM110_chr3_52889460_ENST00000355083_length(transcript)=9252nt_BP=4789nt
TCCATGGGTTCCAAGAGAAGAAGAGCTACCTCCCCTTCCAGCAGTGTCAGCGGGGACTTTGATGATGGGCACCATTCTGTGTCAACACCA
GGCCCAAGCAGGAAAAGGAGGAGACTTTCCAATCTTCCAACTGTAGATCCTATTGCCGTGTGCCATGAACTCTATAATACCATCCGAGAC
TATAAGGATGAACAGGGCAGACTTCTCTGTGAGCTCTTCATTAGGGCACCAAAGCGAAGAAATCAACCAGACTATTATGAAGTGGTTTCT
CAGCCCATTGACTTGATGAAAATCCAACAGAAACTAAAAATGGAAGAGTATGATGATGTTAATTTGCTGACTGCTGACTTCCAGCTTCTT
TTTAACAATGCAAAGTCCTATTATAAGCCAGATTCTCCTGAATATAAAGCCGCTTGCAAACTCTGGGATTTGTACCTTCGAACAAGAAAT
GAGTTTGTTCAGAAAGGAGAAGCAGATGACGAAGATGATGATGAAGATGGGCAAGACAATCAGGGCACAGTGACTGAAGGATCTTCTCCA
GCTTACTTGAAGGAGATCCTGGAGCAGCTTCTTGAAGCCATAGTTGTAGCTACAAATCCATCAGGACGTCTCATTAGCGAACTTTTTCAG
AAACTGCCTTCTAAAGTGCAATATCCAGATTATTATGCAATAATTAAGGAGCCTATAGATCTCAAGACCATTGCCCAGAGGATACAGAAT
GGAAGCTACAAAAGTATTCATGCAATGGCCAAAGATATAGATCTCCTCGCAAAAAATGCCAAAACTTATAATGAGCCTGGCTCTCAAGTA
TTCAAGGATGCAAATTCAATTAAAAAAATATTTTATATGAAAAAGGCTGAAATTGAACATCATGAAATGGCTAAGTCAAGTCTTCGAATG
AGGACTCCATCCAACTTGGCTGCAGCCAGACTGACAGGTCCTTCACACAGTAAAGGCAGCCTTGGTGAAGAGAGAAATCCCACTAGCAAG
TATTACCGTAATAAAAGAGCAGTACAAGGAGGTCGTTTATCAGCAATTACAATGGCACTTCAATATGGCTCAGAAAGTGAAGAAGATGCT
GCTTTAGCTGCTGCACGCTATGAAGAGGGAGAGTCAGAAGCAGAAAGCATCACTTCCTTTATGGATGTTTCAAATCCTTTTTATCAGCTT
TATGACACAGTTAGGAGTTGTCGGAATAACCAAGGGCAGCTAATAGCTGAACCTTTTTACCATTTGCCTTCAAAGAAAAAATACCCTGAT
TATTACCAGCAAATTAAAATGCCCATATCACTACAACAGATCCGAACAAAACTGAAGAATCAAGAATATGAAACTTTAGATCATTTGGAG
TGTGATCTGAATTTAATGTTTGAAAATGCCAAACGCTATAATGTGCCCAATTCAGCCATCTACAAGCGAGTTCTAAAATTGCAGCAAGTT
ATGCAGGCAAAGAAGAAAGAGCTTGCCAGGAGAGACGATATCGAGGACGGAGACAGCATGATCTCTTCAGCCACCTCTGATACTGGTAGT
GCCAAAAGAAAAAGGAACACTCATGACAGTGAGATGTTGGGTCTCAGGAGGCTATCCAGTAAAAAGAACATAAGAAAGCAGCGAATGAAA
ATCTTATTCAATGTTGTTCTTGAAGCTCGAGAGCCAGGTTCAGGCAGAAGACTTTGTGACCTATTTATGGTTAAACCATCCAAAAAGGAC
TATCCTGATTATTATAAAATCATCTTGGAGCCAATGGACTTGAAAATAATTGAGCATAACATCCGCAATGACAAATATGCTGGTGAAGAG
GGAATGATAGAAGACATGAAGCTGATGTTCCGGAATGCCAGGCACTATAATGAGGAGGGCTCCCAGGTTTATAATGATGCACATATCCTG
GAGAAGTTACTCAAGGAGAAAAGGAAAGAGCTGGGCCCACTGCCTGATGATGATGACATGGCTTCTCCCAAACTCAAGCTGAGTAGGAAG
AGTGGCATTTCTCCTAAAAAATCAAAATACATGACTCCAATGCAGCAGAAACTAAATGAGGTCTATGAAGCTGTAAAGAACTATACTGAT
AAGAGGGGTCGCCGCCTCAGTGCCATATTTCTGAGGCTTCCCTCTAGATCTGAGTTGCCTGACTACTATCTGACTATTAAAAAGCCCATG
GACATGGAAAAAATTCGAAGTCACATGATGGCCAACAAGTACCAAGATATTGACTCTATGGTTGAGGACTTTGTCATGATGTTTAATAAT
GCCTGTACATACAATGAGCCGGAGTCTTTGATCTACAAAGATGCTCTTGTTCTACACAAAGTCCTGCTTGAAACACGCAGAGACCTGGAG
GGAGATGAGGACTCTCATGTCCCAAATGTGACTTTGCTGATTCAAGAGCTTATCCACAATCTTTTTGTGTCAGTCATGAGTCATCAGGAT
GATGAGGGAAGATGCTACAGCGATTCTTTAGCAGAAATTCCTGCTGTGGATCCCAACTTTCCTAACAAACCACCCCTTACATTTGACATA
ATTAGGAAGAATGTTGAAAATAATCGCTACCGTCGGCTTGATTTATTTCAAGAGCATATGTTTGAAGTATTGGAACGAGCAAGAAGGATG
AATCGGACAGATTCAGAAATATATGAAGATGCAGTAGAACTTCAGCAGTTTTTTATTAAAATTCGTGATGAACTCTGCAAAAATGGAGAG
ATTCTTCTTTCACCGGCACTCAGCTATACCACAAAACATTTGCATAATGATGTGGAGAAAGAGAGAAAGGAAAAATTGCCAAAAGAAATA
GAGGAAGATAAACTAAAACGAGAAGAAGAAAAAAGAGAAGCTGAAAAGAGTGAAGATTCCTCTGGTGCTGCAGGCCTCTCAGGCTTACAT
CGCACATACAGCCAGGACTGTAGCTTTAAAAACAGCATGTACCATGTTGGAGATTACGTCTATGTGGAACCTGCAGAGGCCAACCTACAA
CCACATATCGTCTGTATTGAAAGACTGTGGGAGGATTCAGCTGGTGAAAAATGGTTGTATGGCTGTTGGTTTTACCGACCAAATGAAACA
TTCCACCTGGCTACACGAAAATTTCTAGAAAAAGAAGTTTTTAAGAGTGACTATTACAACAAAGTTCCAGTTAGTAAAATTCTAGGCAAG
TGTGTGGTCATGTTTGTCAAGGAATACTTTAAGTTATGCCCAGAAAACTTCCGAGATGAGGATGTTTTTGTCTGTGAATCACGGTATTCT
GCCAAAACCAAATCTTTTAAGAAAATTAAACTGTGGACCATGCCCATCAGCTCAGTCAGGTTTGTCCCTCGGGATGTGCCTCTGCCTGTG
GTTCGCGTGGCCTCTGTATTTGCAAATGCAGATAAAGGTGATGATGAGAAGAATACAGACAACTCAGAGGACAGTCGAGCTGAAGACAAT
TTTAACTTGGAAAAGGAAAAAGAAGATGTCCCTGTGGAAATGTCCAATGGTGAACCAGGTTGCCACTACTTTGAGCAGCTCCATTACAAT
GACATGTGGCTGAAGGTTGGCGACTGTGTCTTCATCAAGTCCCATGGCCTGGTGCGTCCTCGTGTGGGCAGAATTGAAAAAGTATGGGTT
CGAGATGGAGCTGCATATTTTTATGGCCCCATCTTCATTCACCCAGAAGAAACAGAGCATGAGCCCACAAAAATGTTCTACAAAAAAGAA
GTATTTCTGAGTAATCTGGAAGAAACCTGCCCCATGACATGTATTCTCGGAAAGTGTGCTGTGTTGTCATTCAAGGACTTCCTCTCCTGC
AGGCCAACTGAAATACCAGAAAATGACATTCTGCTTTGTGAGAGCCGCTACAATGAGAGCGACAAGCAGATGAAGAAATTCAAAGGATTG
AAGAGGTTTTCACTCTCTGCTAAAGTGGTAGATGATGAAATTTACTACTTCAGAAAACCAATTGTTCCTCAGAAGGAGCCATCACCTTTG
CTGGAAAAGAAGATCCAGTTGCTAGAAGCTAAATTTGCCGAGTTAGAAGGTGGAGATGATGATATTGAAGAGATGGGAGAAGAAGATAGT
GAGGTCATTGAACCTCCTTCTCTACCTCAGCTTCAGACCCCCCTGGCCAGTGAGCTGGACCTCATGCCCTACACACCCCCACAGTCTACC
CCAAAGTCTGCCAAAGGCAGTGCAAAGAAGGAAGGCTCCAAACGGAAAATCAACATGAGTGGCTACATCCTGTTCAGCAGTGAGATGAGG
GCTGTGATTAAGGCCCAACACCCAGACTACTCTTTCGGGGAGCTCAGCCGCCTGGTGGGGACAGAATGGAGAAATCTTGAGACAGCCAAG
AAAGCAGAATATGAAGAGCGGGCAGCTAAAGTTGCTGAGCAGCAGGAGAGAGAGCGAGCAGCACAGCAACAGCAGCCGAGTGCTTCTCCC
CGAGCAGGCACCCCTGTGGGGGCTCTCATGGGGGTGGTGCCACCACCAACACCAATGGGGATGCTCAATCAGCAGTTGACACCTGTTGCA
GGTGTGATGAACCAAGGAGTGGCCCCTATGGTAGGGACTCCAGCACCAGGTGGAAGTCCATATGGACAACAGGTGGGAGTTTTGGGGCCT
CCAGGGCAGCAGGCACCACCTCCATATCCCGGCCCACATCCAGCTGGACCCCCTGTCATACAGCAGCCAACAACACCCATGTTTGTAGCT
CCCCCACCAAAGACCCAGCGGCTTCTTCACTCAGAGGCCTACCTGAAATACATTGAAGGACTCAGTGCGGAGTCCAACAGCATTAGCAAG
TGGGATCAGACACTGGCAGTCAAACGCTTCAGAGAACCAAAGCATGAAAGACGTCCGTGGAGGATATGGTTTTTAGACACTTCCAAACAA
GCCATAGGAATGCTGTTCATCCACTTTGCAAATGTATACCTAGCAGATCTCACTGAAGAGGACCCTTGTTCACTGTACCTCATCAACTTC
CTCCTGGACGCCACTGTGGGCATGCTGCTCATCTACGTGGGGGTGCGCGCCGTCAGCGTCCTGGTAGAGTGGCAGCAGTGGGAGTCCCTG
CGCTTCGGCGAATATGGAGACCCTCTGCAGTGTGGAGCCTGGGTCGGGCAGTGCGCTCTTTACATCGTGATCATGATTTTTGAAAAGTCT
GTCGTCTTCATCGTCCTCCTAATACTTCAGTGGAAAAAGGTGGCCCTGTTGAATCCCATTGAAAACCCAGACTTGAAGCTGGCCATCGTC
ATGCTGATCGTCCCCTTCTTTGTCAACGCTTTGATGTTTTGGGTAGTGGACAATTTCCTCATGAGAAAGGGGAAGACGAAAGCTAAGCTA
GAAGAAAGGGGAGCCAACCAGGACTCGAGGAATGGGAGCAAGGTCCGCTACCGGAGGGCCGCATCCCACGAGGAGTCTGAGTCTGAGATC
CTGATCTCAGCGGATGATGAGATGGAGGAGTCCGACGTGGAGGAGGACCTCCGCAGACTGACCCCCCTCAAGCCTGTGAAGAAAAAGAAG
CACCGCTTTGGGCTACCCGTATGACACATTCCCATGCTGGGGGTGACGGGAGGGCCCCGCCAGCCGCTGGTGTGCAGAGGTCATCCCGCA
GCATCGTTCCTTACCCTCTCTCTGCCCTTCCTTTCTACCTCTGCTCCTCTTGCTGTCTCTGCCCGCTCTCGCCTGCCCCCAGACTACTGT
GACTTAAAAAGAGGGAAGAGGAGCCAGCGCCCGAGGGGGCCACTGGCGGCTGGAGGTCCCCATTCAGTTGCACTACAAACACTGACCAAA
TATGCAAGGAAGGAGCTGTGTTTGTTTGTTGTCGTCCCAGACAGTGTTGTGAGGGACCTGAGGCCCTGCCCCGTGTCCGACCACCGAGTG
GCAAGGTGGAAGGAAGCACAGGCACACAGACCGTGGGTGGGTCTCCTCACCGTGGCTGTGGGCAGTGCGAACACATAACACCCTCGGGCT
AAAAGTGACTCGTTGACCAAGTTGGAACCGGAATGCTTTCTTACTCAAAATGGCTTTTGTAACTATTGATTTCTGAAGCTGGTTTTATGA
GTTGTGACAGTGTTACCAGGTTGGGGGTATGTGTTTATTTCCTACAAAGTACTTACGGGACTAATGGGCAAAACAGAGATTTTTAAGTCT
TCCGTATGCTGTTTGACTTTTATATTTTTAAGTTATATTTTCATACTATTGTATTTAAAAACTCTTTTTAGTCCCCAAAGAAATGGGTTT
ATTTGCCTTTCATGGGGTGTGGGCTGGCAGGAGGAAAAATCGGGAGTTTTTTATTTGGAATATTATTAGATGATGCCCTATGATAAGATG
AGACAAATGATGGGGAGGGAAGGAGGATGGCCCTTCTCTAGAATCAGCAAACCCAATGGTTCTGTGAAGGTCAGACCCAAGCTTGGAGCA
GCTGGTCTGGATGCAGATCCAGGAGCTGCAGAGTGTGGAACAGGAAAGGCTCTGCCCAGGGCCCATGAGCTCTAGCATTCCTGCTGGCAG
ATTAGAGATCTTAGTTAAATTTGACCAAGAAAGGAGCTTAGCTAAGAGGTCTTTGTTTCCAGAGGACCCAAGACTACCAGACTCCTGTGC
AGTCTGCCTGTCTGCAGAGCCTCCAATCACGGTTTAAAGTGGTCTTGGCCTCCCAGCCCCCACTGCTGCAGCCTTCAGAGCCAGCCTCTG
GACTCAGCGCCAGGAGCCTCCTCTCCTGCTGCCCTGGTACCTGTCATCCTAGTGTCACCTATTTGTTTTGCACAGCATTCTGGAGAACAT
GTGCCTCACAAAGTGATCCTGTTTTTCTCACCCTCCAAAGCTGAGGTGGCTAAGGGAGGCAGGGGTGAGAGAGCTCACTCTCTAAACCAC
AGGCAGGGCAAGGTGCTTCTAGGCCGTGTCCCCTCCCTGGGGAATGGTCACTACTCCTCAGCATGGCCACAGGCCCCTGTGGTTTTGGGA
GTTTGCTGAGTGACTGTGGAATGGGCTGACCCCAGCCGTTTCCCTGCTGTGGAAACAGCAAGGTAGGGGCACTGCTTGGTGGTTTGTCAA
GCTCAGAGGCAGCCACGGATGGTTAGGAACAGGAAGCCACACTGCTAAGGTGTGATGAGCTAGAAGGGAGACATCCTGGACTTCAAGTGA
GACAAGTGCAGAGGAGGCCACTCCACTTAGGACCTTCCTTTTAGACCTGCATGAGCACGTGTTTCACTTAAGCACATTGGGTCCGAATTG
GGCGCATGAACCCAGCTGTTAAACCAGGTACCCTGGGACTGCCCTCTGCCTCTCAGAGCCCTACCTGTCCTGGACTTGAAGGCGAGCATC
AGGCAGGCCTTCTCAGCCCATCTTCCACCAGGAGTGCAGAGCCAGGGTGCTGAGAGGAGCAGGGACTGTAACTACAGTAGGAGGCAACTT
TGCTGGTGTCATTCCTGCTCGGATTGACTTTGTGCTCCCTCCCATCCACAGCTATGGTAGCCAGTATTTCCCCAGCAGCTCTCTAGTGGG
GAAGAGTGGCTAGAACCAGGCCATTCTCAGTCGAATTTAGGAAGACCAAGACTCATGTTCCTGACAGGACGGTCATTCCCTCATGGCATC
ACTGACTCAGTTCTAATTCCTCCCCTCCTGTTTCATTTTGGTTTGAACAACCTGTGCCTGCAGCTGTTTCTTCCACCTTCCTGGAGCTCA
CAATTGGAGCTTCATGTTCAGTCTTGAGCTCCTAATGTTTCCAGACAGGGCAGGGGATAGGAGAGCCATAATCTATGAAAGCTGTGAAAC
AAACCCTGGGTTATATAGATCTCAGATGGTCTCATCTGAAGGCTTTGCCCACTTCCCAGTGAGCAGAGGGTTTGGGGAACAAAGAGGTAG
CTGAAGAGTGGTGGTTTTTCCCTGTATCCTGATTTTCAGAAAGGGCTTTAGTCTCTGAGCTGTGGCTAGTAGCTGGCTGGCTGACCAGGG
GACGGGGGTCTAATAGGGTGTCTGACCATAGGACACCTCTCGTGTTTGGCCTTCCCTTTCTTGTGTGTTTGTGTGTGTGTGTGCACGTGC
ACGTGCACACACATGTACACACACAAATCTGTATCCCCAGGAGTGCCTCCTGCAGTCACTGGGGGCTCTTCCGTGGTGCACCATCCCATG
AGAGCAGATCAGAGGGCTGTGGTCAGGACTTCCTCCCGAGCTGCCCTCCCTCCCTGGGATGAGTTTCCTCTCCACCTGCTCCAAGGTGCC
TTACGAGGTGCAGCTCTTCACCTGGCCACATGGCATCCATCACCGTGTTGAGAAATGGTGGGACGTTGGCTGGATATTGTGTGCTATGAA
TCTGATTTGTCCAAATCTGGACCTCAGCCAAGCCACCTGTGGTGGAACCTTGCAAGTCAAGGTCATGAACAAATTTCTTGTAACTATTGG
AAATAAACTAATGAGGTAGAACTGTCATATCCAAATGGAAGAGGTGGTTGGTACTGTTACTTCCTTTTGCTGTCAGAGGGTTGTTGACAA
TGGCAAGGGGGGATGTTAGTGAGATCCAGGTGGTGGTGGCTTCTTGGTCCACTCAGCTTGCACACATGCAAGAGGAGGGTCTGTGGCCCC
TCAGCCGTGCTGGTGGCCTCCTTCCTCAAGCTTTAACTTGTGCCCTCCCTGGCAACAGGGAGTCATGGGTTAATGTCACCTGTCATGCCT
CTTTCTTCAGGGAAAATATTAAAAGGCTCAAATCCAAGCTGTGACTTCCCTTAGACAGTGTAAGCCTGTAGGGTGCAGCCCCAAGTTTAT
GTCCAAAGGCTGCCTCAGAACCCTGGAGGGAGCAGCGCCCAGCTGGCAGCTCACTCTGCCCTTGCAGTTCACTGGCCTTTTCGCAGCCAG
GCTAAGATAGGCAGTGCAAGGAGCTTCCCACTGGCCAGAGCAGCTGCCTTGTAGAATGTGGGGCTGGCTTTTAGAAGTTTCACACGCTTG
CAGCTAAGAGTGCAGAGCTCTCTGTTTTACTTCGTGAAACATTAGCAGCTCTGAGGGGCTTGGCTTTTGGTAAGGGACTTATGGTCTGAC
TTGCCACAAGCACCTTGAGCTCCTGGGTTGGTTGGTGGTTGGTTGGTTGGGTTGTTTTAAATTTGATTTTTCTTTTCCTGAAGTTTGTTA
GAAGTCAGACCTATGCAAGGAAAACCATGGCCCACTTCAGCAGCCATCCAGTGGGGGTGCTTAATCGGTGGTGGTAGGATTCATGGAAAC

>63011_63011_5_PBRM1-TMEM110_PBRM1_chr3_52584437_ENST00000409114_TMEM110_chr3_52889460_ENST00000355083_length(amino acids)=1836AA_BP=1593
MGSKRRRATSPSSSVSGDFDDGHHSVSTPGPSRKRRRLSNLPTVDPIAVCHELYNTIRDYKDEQGRLLCELFIRAPKRRNQPDYYEVVSQ
PIDLMKIQQKLKMEEYDDVNLLTADFQLLFNNAKSYYKPDSPEYKAACKLWDLYLRTRNEFVQKGEADDEDDDEDGQDNQGTVTEGSSPA
YLKEILEQLLEAIVVATNPSGRLISELFQKLPSKVQYPDYYAIIKEPIDLKTIAQRIQNGSYKSIHAMAKDIDLLAKNAKTYNEPGSQVF
KDANSIKKIFYMKKAEIEHHEMAKSSLRMRTPSNLAAARLTGPSHSKGSLGEERNPTSKYYRNKRAVQGGRLSAITMALQYGSESEEDAA
LAAARYEEGESEAESITSFMDVSNPFYQLYDTVRSCRNNQGQLIAEPFYHLPSKKKYPDYYQQIKMPISLQQIRTKLKNQEYETLDHLEC
DLNLMFENAKRYNVPNSAIYKRVLKLQQVMQAKKKELARRDDIEDGDSMISSATSDTGSAKRKRNTHDSEMLGLRRLSSKKNIRKQRMKI
LFNVVLEAREPGSGRRLCDLFMVKPSKKDYPDYYKIILEPMDLKIIEHNIRNDKYAGEEGMIEDMKLMFRNARHYNEEGSQVYNDAHILE
KLLKEKRKELGPLPDDDDMASPKLKLSRKSGISPKKSKYMTPMQQKLNEVYEAVKNYTDKRGRRLSAIFLRLPSRSELPDYYLTIKKPMD
MEKIRSHMMANKYQDIDSMVEDFVMMFNNACTYNEPESLIYKDALVLHKVLLETRRDLEGDEDSHVPNVTLLIQELIHNLFVSVMSHQDD
EGRCYSDSLAEIPAVDPNFPNKPPLTFDIIRKNVENNRYRRLDLFQEHMFEVLERARRMNRTDSEIYEDAVELQQFFIKIRDELCKNGEI
LLSPALSYTTKHLHNDVEKERKEKLPKEIEEDKLKREEEKREAEKSEDSSGAAGLSGLHRTYSQDCSFKNSMYHVGDYVYVEPAEANLQP
HIVCIERLWEDSAGEKWLYGCWFYRPNETFHLATRKFLEKEVFKSDYYNKVPVSKILGKCVVMFVKEYFKLCPENFRDEDVFVCESRYSA
KTKSFKKIKLWTMPISSVRFVPRDVPLPVVRVASVFANADKGDDEKNTDNSEDSRAEDNFNLEKEKEDVPVEMSNGEPGCHYFEQLHYND
MWLKVGDCVFIKSHGLVRPRVGRIEKVWVRDGAAYFYGPIFIHPEETEHEPTKMFYKKEVFLSNLEETCPMTCILGKCAVLSFKDFLSCR
PTEIPENDILLCESRYNESDKQMKKFKGLKRFSLSAKVVDDEIYYFRKPIVPQKEPSPLLEKKIQLLEAKFAELEGGDDDIEEMGEEDSE
VIEPPSLPQLQTPLASELDLMPYTPPQSTPKSAKGSAKKEGSKRKINMSGYILFSSEMRAVIKAQHPDYSFGELSRLVGTEWRNLETAKK
AEYEERAAKVAEQQERERAAQQQQPSASPRAGTPVGALMGVVPPPTPMGMLNQQLTPVAGVMNQGVAPMVGTPAPGGSPYGQQVGVLGPP
GQQAPPPYPGPHPAGPPVIQQPTTPMFVAPPPKTQRLLHSEAYLKYIEGLSAESNSISKWDQTLAVKRFREPKHERRPWRIWFLDTSKQA
IGMLFIHFANVYLADLTEEDPCSLYLINFLLDATVGMLLIYVGVRAVSVLVEWQQWESLRFGEYGDPLQCGAWVGQCALYIVIMIFEKSV
VFIVLLILQWKKVALLNPIENPDLKLAIVMLIVPFFVNALMFWVVDNFLMRKGKTKAKLEERGANQDSRNGSKVRYRRAASHEESESEIL

--------------------------------------------------------------
>63011_63011_6_PBRM1-TMEM110_PBRM1_chr3_52584437_ENST00000409767_TMEM110_chr3_52889460_ENST00000355083_length(transcript)=9087nt_BP=4624nt
TCCATGGGTTCCAAGAGAAGAAGAGCTACCTCCCCTTCCAGCAGTGTCAGCGGGGACTTTGATGATGGGCACCATTCTGTGTCAACACCA
GGCCCAAGCAGGAAAAGGAGGAGACTTTCCAATCTTCCAACTGTAGATCCTATTGCCGTGTGCCATGAACTCTATAATACCATCCGAGAC
TATAAGGATGAACAGGGCAGACTTCTCTGTGAGCTCTTCATTAGGGCACCAAAGCGAAGAAATCAACCAGACTATTATGAAGTGGTTTCT
CAGCCCATTGACTTGATGAAAATCCAACAGAAACTAAAAATGGAAGAGTATGATGATGTTAATTTGCTGACTGCTGACTTCCAGCTTCTT
TTTAACAATGCAAAGTCCTATTATAAGCCAGATTCTCCTGAATATAAAGCCGCTTGCAAACTCTGGGATTTGTACCTTCGAACAAGAAAT
GAGTTTGTTCAGAAAGGAGAAGCAGATGACGAAGATGATGATGAAGATGGGCAAGACAATCAGGGCACAGTGACTGAAGGATCTTCTCCA
GCTTACTTGAAGGAGATCCTGGAGCAGCTTCTTGAAGCCATAGTTGTAGCTACAAATCCATCAGGACGTCTCATTAGCGAACTTTTTCAG
AAACTGCCTTCTAAAGTGCAATATCCAGATTATTATGCAATAATTAAGGAGCCTATAGATCTCAAGACCATTGCCCAGAGGATACAGAAT
GGAAGCTACAAAAGTATTCATGCAATGGCCAAAGATATAGATCTCCTCGCAAAAAATGCCAAAACTTATAATGAGCCTGGCTCTCAAGTA
TTCAAGGATGCAAATTCAATTAAAAAAATATTTTATATGAAAAAGGCTGAAATTGAACATCATGAAATGGCTAAGTCAAGTCTTCGAATG
AGGACTCCATCCAACTTGGCTGCAGCCAGACTGACAGGTCCTTCACACAGTAAAGGCAGCCTTGGTGAAGAGAGAAATCCCACTAGCAAG
TATTACCGTAATAAAAGAGCAGTACAAGGAGGTCGTTTATCAGCAATTACAATGGCACTTCAATATGGCTCAGAAAGTGAAGAAGATGCT
GCTTTAGCTGCTGCACGCTATGAAGAGGGAGAGTCAGAAGCAGAAAGCATCACTTCCTTTATGGATGTTTCAAATCCTTTTTATCAGCTT
TATGACACAGTTAGGAGTTGTCGGAATAACCAAGGGCAGCTAATAGCTGAACCTTTTTACCATTTGCCTTCAAAGAAAAAATACCCTGAT
TATTACCAGCAAATTAAAATGCCCATATCACTACAACAGATCCGAACAAAACTGAAGAATCAAGAATATGAAACTTTAGATCATTTGGAG
TGTGATCTGAATTTAATGTTTGAAAATGCCAAACGCTATAATGTGCCCAATTCAGCCATCTACAAGCGAGTTCTAAAATTGCAGCAAGTT
ATGCAGGCAAAGAAGAAAGAGCTTGCCAGGAGAGACGATATCGAGGACGGAGACAGCATGATCTCTTCAGCCACCTCTGATACTGGTAGT
GCCAAAAGAAAAAGGAACACTCATGACAGTGAGATGTTGGGTCTCAGGAGGCTATCCAGTAAAAAGAACATAAGAAAGCAGCGAATGAAA
ATCTTATTCAATGTTGTTCTTGAAGCTCGAGAGCCAGGTTCAGGCAGAAGACTTTGTGACCTATTTATGGTTAAACCATCCAAAAAGGAC
TATCCTGATTATTATAAAATCATCTTGGAGCCAATGGACTTGAAAATAATTGAGCATAACATCCGCAATGACAAATATGCTGGTGAAGAG
GGAATGATAGAAGACATGAAGCTGATGTTCCGGAATGCCAGGCACTATAATGAGGAGGGCTCCCAGGTTTATAATGATGCACATATCCTG
GAGAAGTTACTCAAGGAGAAAAGGAAAGAGCTGGGCCCACTGCCTGATGATGATGACATGGCTTCTCCCAAACTCAAGCTGAGTAGGAAG
AGTGGCATTTCTCCTAAAAAATCAAAATACATGACTCCAATGCAGCAGAAACTAAATGAGGTCTATGAAGCTGTAAAGAACTATACTGAT
AAGAGGGGTCGCCGCCTCAGTGCCATATTTCTGAGGCTTCCCTCTAGATCTGAGTTGCCTGACTACTATCTGACTATTAAAAAGCCCATG
GACATGGAAAAAATTCGAAGTCACATGATGGCCAACAAGTACCAAGATATTGACTCTATGGTTGAGGACTTTGTCATGATGTTTAATAAT
GCCTGTACATACAATGAGCCGGAGTCTTTGATCTACAAAGATGCTCTTGTTCTACACAAAGTCCTGCTTGAAACACGCAGAGACCTGGAG
GGAGATGAGGACTCTCATGTCCCAAATGTGACTTTGCTGATTCAAGAGCTTATCCACAATCTTTTTGTGTCAGTCATGAGTCATCAGGAT
GATGAGGGAAGATGCTACAGCGATTCTTTAGCAGAAATTCCTGCTGTGGATCCCAACTTTCCTAACAAACCACCCCTTACATTTGACATA
ATTAGGAAGAATGTTGAAAATAATCGCTACCGTCGGCTTGATTTATTTCAAGAGCATATGTTTGAAGTATTGGAACGAGCAAGAAGGATG
AATCGGACAGATTCAGAAATATATGAAGATGCAGTAGAACTTCAGCAGTTTTTTATTAAAATTCGTGATGAACTCTGCAAAAATGGAGAG
ATTCTTCTTTCACCGGCACTCAGCTATACCACAAAACATTTGCATAATGATGTGGAGAAAGAGAGAAAGGAAAAATTGCCAAAAGAAATA
GAGGAAGATAAACTAAAACGAGAAGAAGAAAAAAGAGAAGCTGAAAAGAGTGAAGATTCCTCTGGTGCTGCAGGCCTCTCAGGCTTACAT
CGCACATACAGCCAGGACTGTAGCTTTAAAAACAGCATGTACCATGTTGGAGATTACGTCTATGTGGAACCTGCAGAGGCCAACCTACAA
CCACATATCGTCTGTATTGAAAGACTGTGGGAGGATTCAGCTGGTGAAAAATGGTTGTATGGCTGTTGGTTTTACCGACCAAATGAAACA
TTCCACCTGGCTACACGAAAATTTCTAGAAAAAGAAGTTTTTAAGAGTGACTATTACAACAAAGTTCCAGTTAGTAAAATTCTAGGCAAG
TGTGTGGTCATGTTTGTCAAGGAATACTTTAAGTTATGCCCAGAAAACTTCCGAGATGAGGATGTTTTTGTCTGTGAATCACGGTATTCT
GCCAAAACCAAATCTTTTAAGAAAATTAAACTGTGGACCATGCCCATCAGCTCAGTCAGGTTTGTCCCTCGGGATGTGCCTCTGCCTGTG
GTTCGCGTGGCCTCTGTATTTGCAAATGCAGATAAAGGTGATGATGAGAAGAATACAGACAACTCAGAGGACAGTCGAGCTGAAGACAAT
TTTAACTTGGAAAAGGAAAAAGAAGATGTCCCTGTGGAAATGTCCAATGGTGAACCAGGTTGCCACTACTTTGAGCAGCTCCATTACAAT
GACATGTGGCTGAAGGTTGGCGACTGTGTCTTCATCAAGTCCCATGGCCTGGTGCGTCCTCGTGTGGGCAGAATTGAAAAAGTATGGGTT
CGAGATGGAGCTGCATATTTTTATGGCCCCATCTTCATTCACCCAGAAGAAACAGAGCATGAGCCCACAAAAATGTTCTACAAAAAAGAA
GTATTTCTGAGTAATCTGGAAGAAACCTGCCCCATGACATGTATTCTCGGAAAGTGTGCTGTGTTGTCATTCAAGGACTTCCTCTCCTGC
AGGCCAACTGAAATACCAGAAAATGACATTCTGCTTTGTGAGAGCCGCTACAATGAGAGCGACAAGCAGATGAAGAAATTCAAAGGATTG
AAGAGGTTTTCACTCTCTGCTAAAGTGGTAGATGATGAAATTTACTACTTCAGAAAACCAATTGTTCCTCAGAAGGAGCCATCACCTTTG
CTGGAAAAGAAGATCCAGTTGCTAGAAGCTAAATTTGCCGAGTTAGAAGGTGGAGATGATGATATTGAAGAGATGGGAGAAGAAGATAGT
GAGGTCATTGAACCTCCTTCTCTACCTCAGCTTCAGACCCCCCTGGCCAGTGAGCTGGACCTCATGCCCTACACACCCCCACAGTCTACC
CCAAAGTCTGCCAAAGGCAGTGCAAAGAAGGAAGGCTCCAAACGGAAAATCAACATGAGTGGCTACATCCTGTTCAGCAGTGAGATGAGG
GCTGTGATTAAGGCCCAACACCCAGACTACTCTTTCGGGGAGCTCAGCCGCCTGGTGGGGACAGAATGGAGAAATCTTGAGACAGCCAAG
AAAGCAGAATATGAAGGTGTGATGAACCAAGGAGTGGCCCCTATGGTAGGGACTCCAGCACCAGGTGGAAGTCCATATGGACAACAGGTG
GGAGTTTTGGGGCCTCCAGGGCAGCAGGCACCACCTCCATATCCCGGCCCACATCCAGCTGGACCCCCTGTCATACAGCAGCCAACAACA
CCCATGTTTGTAGCTCCCCCACCAAAGACCCAGCGGCTTCTTCACTCAGAGGCCTACCTGAAATACATTGAAGGACTCAGTGCGGAGTCC
AACAGCATTAGCAAGTGGGATCAGACACTGGCAGTCAAACGCTTCAGAGAACCAAAGCATGAAAGACGTCCGTGGAGGATATGGTTTTTA
GACACTTCCAAACAAGCCATAGGAATGCTGTTCATCCACTTTGCAAATGTATACCTAGCAGATCTCACTGAAGAGGACCCTTGTTCACTG
TACCTCATCAACTTCCTCCTGGACGCCACTGTGGGCATGCTGCTCATCTACGTGGGGGTGCGCGCCGTCAGCGTCCTGGTAGAGTGGCAG
CAGTGGGAGTCCCTGCGCTTCGGCGAATATGGAGACCCTCTGCAGTGTGGAGCCTGGGTCGGGCAGTGCGCTCTTTACATCGTGATCATG
ATTTTTGAAAAGTCTGTCGTCTTCATCGTCCTCCTAATACTTCAGTGGAAAAAGGTGGCCCTGTTGAATCCCATTGAAAACCCAGACTTG
AAGCTGGCCATCGTCATGCTGATCGTCCCCTTCTTTGTCAACGCTTTGATGTTTTGGGTAGTGGACAATTTCCTCATGAGAAAGGGGAAG
ACGAAAGCTAAGCTAGAAGAAAGGGGAGCCAACCAGGACTCGAGGAATGGGAGCAAGGTCCGCTACCGGAGGGCCGCATCCCACGAGGAG
TCTGAGTCTGAGATCCTGATCTCAGCGGATGATGAGATGGAGGAGTCCGACGTGGAGGAGGACCTCCGCAGACTGACCCCCCTCAAGCCT
GTGAAGAAAAAGAAGCACCGCTTTGGGCTACCCGTATGACACATTCCCATGCTGGGGGTGACGGGAGGGCCCCGCCAGCCGCTGGTGTGC
AGAGGTCATCCCGCAGCATCGTTCCTTACCCTCTCTCTGCCCTTCCTTTCTACCTCTGCTCCTCTTGCTGTCTCTGCCCGCTCTCGCCTG
CCCCCAGACTACTGTGACTTAAAAAGAGGGAAGAGGAGCCAGCGCCCGAGGGGGCCACTGGCGGCTGGAGGTCCCCATTCAGTTGCACTA
CAAACACTGACCAAATATGCAAGGAAGGAGCTGTGTTTGTTTGTTGTCGTCCCAGACAGTGTTGTGAGGGACCTGAGGCCCTGCCCCGTG
TCCGACCACCGAGTGGCAAGGTGGAAGGAAGCACAGGCACACAGACCGTGGGTGGGTCTCCTCACCGTGGCTGTGGGCAGTGCGAACACA
TAACACCCTCGGGCTAAAAGTGACTCGTTGACCAAGTTGGAACCGGAATGCTTTCTTACTCAAAATGGCTTTTGTAACTATTGATTTCTG
AAGCTGGTTTTATGAGTTGTGACAGTGTTACCAGGTTGGGGGTATGTGTTTATTTCCTACAAAGTACTTACGGGACTAATGGGCAAAACA
GAGATTTTTAAGTCTTCCGTATGCTGTTTGACTTTTATATTTTTAAGTTATATTTTCATACTATTGTATTTAAAAACTCTTTTTAGTCCC
CAAAGAAATGGGTTTATTTGCCTTTCATGGGGTGTGGGCTGGCAGGAGGAAAAATCGGGAGTTTTTTATTTGGAATATTATTAGATGATG
CCCTATGATAAGATGAGACAAATGATGGGGAGGGAAGGAGGATGGCCCTTCTCTAGAATCAGCAAACCCAATGGTTCTGTGAAGGTCAGA
CCCAAGCTTGGAGCAGCTGGTCTGGATGCAGATCCAGGAGCTGCAGAGTGTGGAACAGGAAAGGCTCTGCCCAGGGCCCATGAGCTCTAG
CATTCCTGCTGGCAGATTAGAGATCTTAGTTAAATTTGACCAAGAAAGGAGCTTAGCTAAGAGGTCTTTGTTTCCAGAGGACCCAAGACT
ACCAGACTCCTGTGCAGTCTGCCTGTCTGCAGAGCCTCCAATCACGGTTTAAAGTGGTCTTGGCCTCCCAGCCCCCACTGCTGCAGCCTT
CAGAGCCAGCCTCTGGACTCAGCGCCAGGAGCCTCCTCTCCTGCTGCCCTGGTACCTGTCATCCTAGTGTCACCTATTTGTTTTGCACAG
CATTCTGGAGAACATGTGCCTCACAAAGTGATCCTGTTTTTCTCACCCTCCAAAGCTGAGGTGGCTAAGGGAGGCAGGGGTGAGAGAGCT
CACTCTCTAAACCACAGGCAGGGCAAGGTGCTTCTAGGCCGTGTCCCCTCCCTGGGGAATGGTCACTACTCCTCAGCATGGCCACAGGCC
CCTGTGGTTTTGGGAGTTTGCTGAGTGACTGTGGAATGGGCTGACCCCAGCCGTTTCCCTGCTGTGGAAACAGCAAGGTAGGGGCACTGC
TTGGTGGTTTGTCAAGCTCAGAGGCAGCCACGGATGGTTAGGAACAGGAAGCCACACTGCTAAGGTGTGATGAGCTAGAAGGGAGACATC
CTGGACTTCAAGTGAGACAAGTGCAGAGGAGGCCACTCCACTTAGGACCTTCCTTTTAGACCTGCATGAGCACGTGTTTCACTTAAGCAC
ATTGGGTCCGAATTGGGCGCATGAACCCAGCTGTTAAACCAGGTACCCTGGGACTGCCCTCTGCCTCTCAGAGCCCTACCTGTCCTGGAC
TTGAAGGCGAGCATCAGGCAGGCCTTCTCAGCCCATCTTCCACCAGGAGTGCAGAGCCAGGGTGCTGAGAGGAGCAGGGACTGTAACTAC
AGTAGGAGGCAACTTTGCTGGTGTCATTCCTGCTCGGATTGACTTTGTGCTCCCTCCCATCCACAGCTATGGTAGCCAGTATTTCCCCAG
CAGCTCTCTAGTGGGGAAGAGTGGCTAGAACCAGGCCATTCTCAGTCGAATTTAGGAAGACCAAGACTCATGTTCCTGACAGGACGGTCA
TTCCCTCATGGCATCACTGACTCAGTTCTAATTCCTCCCCTCCTGTTTCATTTTGGTTTGAACAACCTGTGCCTGCAGCTGTTTCTTCCA
CCTTCCTGGAGCTCACAATTGGAGCTTCATGTTCAGTCTTGAGCTCCTAATGTTTCCAGACAGGGCAGGGGATAGGAGAGCCATAATCTA
TGAAAGCTGTGAAACAAACCCTGGGTTATATAGATCTCAGATGGTCTCATCTGAAGGCTTTGCCCACTTCCCAGTGAGCAGAGGGTTTGG
GGAACAAAGAGGTAGCTGAAGAGTGGTGGTTTTTCCCTGTATCCTGATTTTCAGAAAGGGCTTTAGTCTCTGAGCTGTGGCTAGTAGCTG
GCTGGCTGACCAGGGGACGGGGGTCTAATAGGGTGTCTGACCATAGGACACCTCTCGTGTTTGGCCTTCCCTTTCTTGTGTGTTTGTGTG
TGTGTGTGCACGTGCACGTGCACACACATGTACACACACAAATCTGTATCCCCAGGAGTGCCTCCTGCAGTCACTGGGGGCTCTTCCGTG
GTGCACCATCCCATGAGAGCAGATCAGAGGGCTGTGGTCAGGACTTCCTCCCGAGCTGCCCTCCCTCCCTGGGATGAGTTTCCTCTCCAC
CTGCTCCAAGGTGCCTTACGAGGTGCAGCTCTTCACCTGGCCACATGGCATCCATCACCGTGTTGAGAAATGGTGGGACGTTGGCTGGAT
ATTGTGTGCTATGAATCTGATTTGTCCAAATCTGGACCTCAGCCAAGCCACCTGTGGTGGAACCTTGCAAGTCAAGGTCATGAACAAATT
TCTTGTAACTATTGGAAATAAACTAATGAGGTAGAACTGTCATATCCAAATGGAAGAGGTGGTTGGTACTGTTACTTCCTTTTGCTGTCA
GAGGGTTGTTGACAATGGCAAGGGGGGATGTTAGTGAGATCCAGGTGGTGGTGGCTTCTTGGTCCACTCAGCTTGCACACATGCAAGAGG
AGGGTCTGTGGCCCCTCAGCCGTGCTGGTGGCCTCCTTCCTCAAGCTTTAACTTGTGCCCTCCCTGGCAACAGGGAGTCATGGGTTAATG
TCACCTGTCATGCCTCTTTCTTCAGGGAAAATATTAAAAGGCTCAAATCCAAGCTGTGACTTCCCTTAGACAGTGTAAGCCTGTAGGGTG
CAGCCCCAAGTTTATGTCCAAAGGCTGCCTCAGAACCCTGGAGGGAGCAGCGCCCAGCTGGCAGCTCACTCTGCCCTTGCAGTTCACTGG
CCTTTTCGCAGCCAGGCTAAGATAGGCAGTGCAAGGAGCTTCCCACTGGCCAGAGCAGCTGCCTTGTAGAATGTGGGGCTGGCTTTTAGA
AGTTTCACACGCTTGCAGCTAAGAGTGCAGAGCTCTCTGTTTTACTTCGTGAAACATTAGCAGCTCTGAGGGGCTTGGCTTTTGGTAAGG
GACTTATGGTCTGACTTGCCACAAGCACCTTGAGCTCCTGGGTTGGTTGGTGGTTGGTTGGTTGGGTTGTTTTAAATTTGATTTTTCTTT
TCCTGAAGTTTGTTAGAAGTCAGACCTATGCAAGGAAAACCATGGCCCACTTCAGCAGCCATCCAGTGGGGGTGCTTAATCGGTGGTGGT

>63011_63011_6_PBRM1-TMEM110_PBRM1_chr3_52584437_ENST00000409767_TMEM110_chr3_52889460_ENST00000355083_length(amino acids)=1781AA_BP=1538
MGSKRRRATSPSSSVSGDFDDGHHSVSTPGPSRKRRRLSNLPTVDPIAVCHELYNTIRDYKDEQGRLLCELFIRAPKRRNQPDYYEVVSQ
PIDLMKIQQKLKMEEYDDVNLLTADFQLLFNNAKSYYKPDSPEYKAACKLWDLYLRTRNEFVQKGEADDEDDDEDGQDNQGTVTEGSSPA
YLKEILEQLLEAIVVATNPSGRLISELFQKLPSKVQYPDYYAIIKEPIDLKTIAQRIQNGSYKSIHAMAKDIDLLAKNAKTYNEPGSQVF
KDANSIKKIFYMKKAEIEHHEMAKSSLRMRTPSNLAAARLTGPSHSKGSLGEERNPTSKYYRNKRAVQGGRLSAITMALQYGSESEEDAA
LAAARYEEGESEAESITSFMDVSNPFYQLYDTVRSCRNNQGQLIAEPFYHLPSKKKYPDYYQQIKMPISLQQIRTKLKNQEYETLDHLEC
DLNLMFENAKRYNVPNSAIYKRVLKLQQVMQAKKKELARRDDIEDGDSMISSATSDTGSAKRKRNTHDSEMLGLRRLSSKKNIRKQRMKI
LFNVVLEAREPGSGRRLCDLFMVKPSKKDYPDYYKIILEPMDLKIIEHNIRNDKYAGEEGMIEDMKLMFRNARHYNEEGSQVYNDAHILE
KLLKEKRKELGPLPDDDDMASPKLKLSRKSGISPKKSKYMTPMQQKLNEVYEAVKNYTDKRGRRLSAIFLRLPSRSELPDYYLTIKKPMD
MEKIRSHMMANKYQDIDSMVEDFVMMFNNACTYNEPESLIYKDALVLHKVLLETRRDLEGDEDSHVPNVTLLIQELIHNLFVSVMSHQDD
EGRCYSDSLAEIPAVDPNFPNKPPLTFDIIRKNVENNRYRRLDLFQEHMFEVLERARRMNRTDSEIYEDAVELQQFFIKIRDELCKNGEI
LLSPALSYTTKHLHNDVEKERKEKLPKEIEEDKLKREEEKREAEKSEDSSGAAGLSGLHRTYSQDCSFKNSMYHVGDYVYVEPAEANLQP
HIVCIERLWEDSAGEKWLYGCWFYRPNETFHLATRKFLEKEVFKSDYYNKVPVSKILGKCVVMFVKEYFKLCPENFRDEDVFVCESRYSA
KTKSFKKIKLWTMPISSVRFVPRDVPLPVVRVASVFANADKGDDEKNTDNSEDSRAEDNFNLEKEKEDVPVEMSNGEPGCHYFEQLHYND
MWLKVGDCVFIKSHGLVRPRVGRIEKVWVRDGAAYFYGPIFIHPEETEHEPTKMFYKKEVFLSNLEETCPMTCILGKCAVLSFKDFLSCR
PTEIPENDILLCESRYNESDKQMKKFKGLKRFSLSAKVVDDEIYYFRKPIVPQKEPSPLLEKKIQLLEAKFAELEGGDDDIEEMGEEDSE
VIEPPSLPQLQTPLASELDLMPYTPPQSTPKSAKGSAKKEGSKRKINMSGYILFSSEMRAVIKAQHPDYSFGELSRLVGTEWRNLETAKK
AEYEGVMNQGVAPMVGTPAPGGSPYGQQVGVLGPPGQQAPPPYPGPHPAGPPVIQQPTTPMFVAPPPKTQRLLHSEAYLKYIEGLSAESN
SISKWDQTLAVKRFREPKHERRPWRIWFLDTSKQAIGMLFIHFANVYLADLTEEDPCSLYLINFLLDATVGMLLIYVGVRAVSVLVEWQQ
WESLRFGEYGDPLQCGAWVGQCALYIVIMIFEKSVVFIVLLILQWKKVALLNPIENPDLKLAIVMLIVPFFVNALMFWVVDNFLMRKGKT

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>63011_63011_7_PBRM1-TMEM110_PBRM1_chr3_52584437_ENST00000410007_TMEM110_chr3_52889460_ENST00000355083_length(transcript)=9123nt_BP=4660nt
TCCATGGGTTCCAAGAGAAGAAGAGCTACCTCCCCTTCCAGCAGTGTCAGCGGGGACTTTGATGATGGGCACCATTCTGTGTCAACACCA
GGCCCAAGCAGGAAAAGGAGGAGACTTTCCAATCTTCCAACTGTAGATCCTATTGCCGTGTGCCATGAACTCTATAATACCATCCGAGAC
TATAAGGATGAACAGGGCAGACTTCTCTGTGAGCTCTTCATTAGGGCACCAAAGCGAAGAAATCAACCAGACTATTATGAAGTGGTTTCT
CAGCCCATTGACTTGATGAAAATCCAACAGAAACTAAAAATGGAAGAGTATGATGATGTTAATTTGCTGACTGCTGACTTCCAGCTTCTT
TTTAACAATGCAAAGTCCTATTATAAGCCAGATTCTCCTGAATATAAAGCCGCTTGCAAACTCTGGGATTTGTACCTTCGAACAAGAAAT
GAGTTTGTTCAGAAAGGAGAAGCAGATGACGAAGATGATGATGAAGATGGGCAAGACAATCAGGGCACAGTGACTGAAGGATCTTCTCCA
GCTTACTTGAAGGAGATCCTGGAGCAGCTTCTTGAAGCCATAGTTGTAGCTACAAATCCATCAGGACGTCTCATTAGCGAACTTTTTCAG
AAACTGCCTTCTAAAGTGCAATATCCAGATTATTATGCAATAATTAAGGAGCCTATAGATCTCAAGACCATTGCCCAGAGGATACAGAAT
GGAAGCTACAAAAGTATTCATGCAATGGCCAAAGATATAGATCTCCTCGCAAAAAATGCCAAAACTTATAATGAGCCTGGCTCTCAAGTA
TTCAAGGATGCAAATTCAATTAAAAAAATATTTTATATGAAAAAGGCTGAAATTGAACATCATGAAATGGCTAAGTCAAGTCTTCGAATG
AGGACTCCATCCAACTTGGCTGCAGCCAGACTGACAGGTCCTTCACACAGTAAAGGCAGCCTTGGTGAAGAGAGAAATCCCACTAGCAAG
TATTACCGTAATAAAAGAGCAGTACAAGGAGGTCGTTTATCAGCAATTACAATGGCACTTCAATATGGCTCAGAAAGTGAAGAAGATGCT
GCTTTAGCTGCTGCACGCTATGAAGAGGGAGAGTCAGAAGCAGAAAGCATCACTTCCTTTATGGATGTTTCAAATCCTTTTTATCAGCTT
TATGACACAGTTAGGAGTTGTCGGAATAACCAAGGGCAGCTAATAGCTGAACCTTTTTACCATTTGCCTTCAAAGAAAAAATACCCTGAT
TATTACCAGCAAATTAAAATGCCCATATCACTACAACAGATCCGAACAAAACTGAAGAATCAAGAATATGAAACTTTAGATCATTTGGAG
TGTGATCTGAATTTAATGTTTGAAAATGCCAAACGCTATAATGTGCCCAATTCAGCCATCTACAAGCGAGTTCTAAAATTGCAGCAAGTT
ATGCAGGCAAAGAAGAAAGAGCTTGCCAGGAGAGACGATATCGAGGACGGAGACAGCATGATCTCTTCAGCCACCTCTGATACTGGTAGT
GCCAAAAGAAAAAGTAAAAAGAACATAAGAAAGCAGCGAATGAAAATCTTATTCAATGTTGTTCTTGAAGCTCGAGAGCCAGGTTCAGGC
AGAAGACTTTGTGACCTATTTATGGTTAAACCATCCAAAAAGGACTATCCTGATTATTATAAAATCATCTTGGAGCCAATGGACTTGAAA
ATAATTGAGCATAACATCCGCAATGACAAATATGCTGGTGAAGAGGGAATGATAGAAGACATGAAGCTGATGTTCCGGAATGCCAGGCAC
TATAATGAGGAGGGCTCCCAGGTTTATAATGATGCACATATCCTGGAGAAGTTACTCAAGGAGAAAAGGAAAGAGCTGGGCCCACTGCCT
GATGATGATGACATGGCTTCTCCCAAACTCAAGCTGAGTAGGAAGAGTGGCATTTCTCCTAAAAAATCAAAATACATGACTCCAATGCAG
CAGAAACTAAATGAGGTCTATGAAGCTGTAAAGAACTATACTGATAAGAGGGGTCGCCGCCTCAGTGCCATATTTCTGAGGCTTCCCTCT
AGATCTGAGTTGCCTGACTACTATCTGACTATTAAAAAGCCCATGGACATGGAAAAAATTCGAAGTCACATGATGGCCAACAAGTACCAA
GATATTGACTCTATGGTTGAGGACTTTGTCATGATGTTTAATAATGCCTGTACATACAATGAGCCGGAGTCTTTGATCTACAAAGATGCT
CTTGTTCTACACAAAGTCCTGCTTGAAACACGCAGAGACCTGGAGGGAGATGAGGACTCTCATGTCCCAAATGTGACTTTGCTGATTCAA
GAGCTTATCCACAATCTTTTTGTGTCAGTCATGAGTCATCAGGATGATGAGGGAAGATGCTACAGCGATTCTTTAGCAGAAATTCCTGCT
GTGGATCCCAACTTTCCTAACAAACCACCCCTTACATTTGACATAATTAGGAAGAATGTTGAAAATAATCGCTACCGTCGGCTTGATTTA
TTTCAAGAGCATATGTTTGAAGTATTGGAACGAGCAAGAAGGATGAATCGGACAGATTCAGAAATATATGAAGATGCAGTAGAACTTCAG
CAGTTTTTTATTAAAATTCGTGATGAACTCTGCAAAAATGGAGAGATTCTTCTTTCACCGGCACTCAGCTATACCACAAAACATTTGCAT
AATGATGTGGAGAAAGAGAGAAAGGAAAAATTGCCAAAAGAAATAGAGGAAGATAAACTAAAACGAGAAGAAGAAAAAAGAGAAGCTGAA
AAGAGTGAAGATTCCTCTGGTGCTGCAGGCCTCTCAGGCTTACATCGCACATACAGCCAGGACTGTAGCTTTAAAAACAGCATGTACCAT
GTTGGAGATTACGTCTATGTGGAACCTGCAGAGGCCAACCTACAACCACATATCGTCTGTATTGAAAGACTGTGGGAGGATTCAGCTGAA
AAAGAAGTTTTTAAGAGTGACTATTACAACAAAGTTCCAGTTAGTAAAATTCTAGGCAAGTGTGTGGTCATGTTTGTCAAGGAATACTTT
AAGTTATGCCCAGAAAACTTCCGAGATGAGGATGTTTTTGTCTGTGAATCACGGTATTCTGCCAAAACCAAATCTTTTAAGAAAATTAAA
CTGTGGACCATGCCCATCAGCTCAGTCAGGTTTGTCCCTCGGGATGTGCCTCTGCCTGTGGTTCGCGTGGCCTCTGTATTTGCAAATGCA
GATAAAGGTGATGATGAGAAGAATACAGACAACTCAGAGGACAGTCGAGCTGAAGACAATTTTAACTTGGAAAAGGAAAAAGAAGATGTC
CCTGTGGAAATGTCCAATGGTGAACCAGGTTGCCACTACTTTGAGCAGCTCCATTACAATGACATGTGGCTGAAGGTTGGCGACTGTGTC
TTCATCAAGTCCCATGGCCTGGTGCGTCCTCGTGTGGGCAGAATTGAAAAAGTATGGGTTCGAGATGGAGCTGCATATTTTTATGGCCCC
ATCTTCATTCACCCAGAAGAAACAGAGCATGAGCCCACAAAAATGTTCTACAAAAAAGAAGTATTTCTGAGTAATCTGGAAGAAACCTGC
CCCATGACATGTATTCTCGGAAAGTGTGCTGTGTTGTCATTCAAGGACTTCCTCTCCTGCAGGCCAACTGAAATACCAGAAAATGACATT
CTGCTTTGTGAGAGCCGCTACAATGAGAGCGACAAGCAGATGAAGAAATTCAAAGGATTGAAGAGGTTTTCACTCTCTGCTAAAGTGGTA
GATGATGAAATTTACTACTTCAGAAAACCAATTGTTCCTCAGAAGGAGCCATCACCTTTGCTGGAAAAGAAGATCCAGTTGCTAGAAGCT
AAATTTGCCGAGTTAGAAGGTGGAGATGATGATATTGAAGAGATGGGAGAAGAAGATAGTGAGGTCATTGAACCTCCTTCTCTACCTCAG
CTTCAGACCCCCCTGGCCAGTGAGCTGGACCTCATGCCCTACACACCCCCACAGTCTACCCCAAAGTCTGCCAAAGGCAGTGCAAAGAAG
GAAGGCTCCAAACGGAAAATCAACATGAGTGGCTACATCCTGTTCAGCAGTGAGATGAGGGCTGTGATTAAGGCCCAACACCCAGACTAC
TCTTTCGGGGAGCTCAGCCGCCTGGTGGGGACAGAATGGAGAAATCTTGAGACAGCCAAGAAAGCAGAATATGAAGGCATGATGGGTGGC
TATCCGCCAGGCCTTCCACCTTTGCAGGGCCCAGTTGATGGCCTTGTTAGCATGGGCAGCATGCAGCCACTTCACCCTGGGGGGCCTCCA
CCCCACCATCTTCCGCCAGGTGTGCCTGGCCTCCCGGGCATCCCACCACCGGGTGTGATGAACCAAGGAGTGGCCCCTATGGTAGGGACT
CCAGCACCAGGTGGAAGTCCATATGGACAACAGGTGGGAGTTTTGGGGCCTCCAGGGCAGCAGGCACCACCTCCATATCCCGGCCCACAT
CCAGCTGGACCCCCTGTCATACAGCAGCCAACAACACCCATGTTTGTAGCTCCCCCACCAAAGACCCAGCGGCTTCTTCACTCAGAGGCC
TACCTGAAATACATTGAAGGACTCAGTGCGGAGTCCAACAGCATTAGCAAGTGGGATCAGACACTGGCAGTCAAACGCTTCAGAGAACCA
AAGCATGAAAGACGTCCGTGGAGGATATGGTTTTTAGACACTTCCAAACAAGCCATAGGAATGCTGTTCATCCACTTTGCAAATGTATAC
CTAGCAGATCTCACTGAAGAGGACCCTTGTTCACTGTACCTCATCAACTTCCTCCTGGACGCCACTGTGGGCATGCTGCTCATCTACGTG
GGGGTGCGCGCCGTCAGCGTCCTGGTAGAGTGGCAGCAGTGGGAGTCCCTGCGCTTCGGCGAATATGGAGACCCTCTGCAGTGTGGAGCC
TGGGTCGGGCAGTGCGCTCTTTACATCGTGATCATGATTTTTGAAAAGTCTGTCGTCTTCATCGTCCTCCTAATACTTCAGTGGAAAAAG
GTGGCCCTGTTGAATCCCATTGAAAACCCAGACTTGAAGCTGGCCATCGTCATGCTGATCGTCCCCTTCTTTGTCAACGCTTTGATGTTT
TGGGTAGTGGACAATTTCCTCATGAGAAAGGGGAAGACGAAAGCTAAGCTAGAAGAAAGGGGAGCCAACCAGGACTCGAGGAATGGGAGC
AAGGTCCGCTACCGGAGGGCCGCATCCCACGAGGAGTCTGAGTCTGAGATCCTGATCTCAGCGGATGATGAGATGGAGGAGTCCGACGTG
GAGGAGGACCTCCGCAGACTGACCCCCCTCAAGCCTGTGAAGAAAAAGAAGCACCGCTTTGGGCTACCCGTATGACACATTCCCATGCTG
GGGGTGACGGGAGGGCCCCGCCAGCCGCTGGTGTGCAGAGGTCATCCCGCAGCATCGTTCCTTACCCTCTCTCTGCCCTTCCTTTCTACC
TCTGCTCCTCTTGCTGTCTCTGCCCGCTCTCGCCTGCCCCCAGACTACTGTGACTTAAAAAGAGGGAAGAGGAGCCAGCGCCCGAGGGGG
CCACTGGCGGCTGGAGGTCCCCATTCAGTTGCACTACAAACACTGACCAAATATGCAAGGAAGGAGCTGTGTTTGTTTGTTGTCGTCCCA
GACAGTGTTGTGAGGGACCTGAGGCCCTGCCCCGTGTCCGACCACCGAGTGGCAAGGTGGAAGGAAGCACAGGCACACAGACCGTGGGTG
GGTCTCCTCACCGTGGCTGTGGGCAGTGCGAACACATAACACCCTCGGGCTAAAAGTGACTCGTTGACCAAGTTGGAACCGGAATGCTTT
CTTACTCAAAATGGCTTTTGTAACTATTGATTTCTGAAGCTGGTTTTATGAGTTGTGACAGTGTTACCAGGTTGGGGGTATGTGTTTATT
TCCTACAAAGTACTTACGGGACTAATGGGCAAAACAGAGATTTTTAAGTCTTCCGTATGCTGTTTGACTTTTATATTTTTAAGTTATATT
TTCATACTATTGTATTTAAAAACTCTTTTTAGTCCCCAAAGAAATGGGTTTATTTGCCTTTCATGGGGTGTGGGCTGGCAGGAGGAAAAA
TCGGGAGTTTTTTATTTGGAATATTATTAGATGATGCCCTATGATAAGATGAGACAAATGATGGGGAGGGAAGGAGGATGGCCCTTCTCT
AGAATCAGCAAACCCAATGGTTCTGTGAAGGTCAGACCCAAGCTTGGAGCAGCTGGTCTGGATGCAGATCCAGGAGCTGCAGAGTGTGGA
ACAGGAAAGGCTCTGCCCAGGGCCCATGAGCTCTAGCATTCCTGCTGGCAGATTAGAGATCTTAGTTAAATTTGACCAAGAAAGGAGCTT
AGCTAAGAGGTCTTTGTTTCCAGAGGACCCAAGACTACCAGACTCCTGTGCAGTCTGCCTGTCTGCAGAGCCTCCAATCACGGTTTAAAG
TGGTCTTGGCCTCCCAGCCCCCACTGCTGCAGCCTTCAGAGCCAGCCTCTGGACTCAGCGCCAGGAGCCTCCTCTCCTGCTGCCCTGGTA
CCTGTCATCCTAGTGTCACCTATTTGTTTTGCACAGCATTCTGGAGAACATGTGCCTCACAAAGTGATCCTGTTTTTCTCACCCTCCAAA
GCTGAGGTGGCTAAGGGAGGCAGGGGTGAGAGAGCTCACTCTCTAAACCACAGGCAGGGCAAGGTGCTTCTAGGCCGTGTCCCCTCCCTG
GGGAATGGTCACTACTCCTCAGCATGGCCACAGGCCCCTGTGGTTTTGGGAGTTTGCTGAGTGACTGTGGAATGGGCTGACCCCAGCCGT
TTCCCTGCTGTGGAAACAGCAAGGTAGGGGCACTGCTTGGTGGTTTGTCAAGCTCAGAGGCAGCCACGGATGGTTAGGAACAGGAAGCCA
CACTGCTAAGGTGTGATGAGCTAGAAGGGAGACATCCTGGACTTCAAGTGAGACAAGTGCAGAGGAGGCCACTCCACTTAGGACCTTCCT
TTTAGACCTGCATGAGCACGTGTTTCACTTAAGCACATTGGGTCCGAATTGGGCGCATGAACCCAGCTGTTAAACCAGGTACCCTGGGAC
TGCCCTCTGCCTCTCAGAGCCCTACCTGTCCTGGACTTGAAGGCGAGCATCAGGCAGGCCTTCTCAGCCCATCTTCCACCAGGAGTGCAG
AGCCAGGGTGCTGAGAGGAGCAGGGACTGTAACTACAGTAGGAGGCAACTTTGCTGGTGTCATTCCTGCTCGGATTGACTTTGTGCTCCC
TCCCATCCACAGCTATGGTAGCCAGTATTTCCCCAGCAGCTCTCTAGTGGGGAAGAGTGGCTAGAACCAGGCCATTCTCAGTCGAATTTA
GGAAGACCAAGACTCATGTTCCTGACAGGACGGTCATTCCCTCATGGCATCACTGACTCAGTTCTAATTCCTCCCCTCCTGTTTCATTTT
GGTTTGAACAACCTGTGCCTGCAGCTGTTTCTTCCACCTTCCTGGAGCTCACAATTGGAGCTTCATGTTCAGTCTTGAGCTCCTAATGTT
TCCAGACAGGGCAGGGGATAGGAGAGCCATAATCTATGAAAGCTGTGAAACAAACCCTGGGTTATATAGATCTCAGATGGTCTCATCTGA
AGGCTTTGCCCACTTCCCAGTGAGCAGAGGGTTTGGGGAACAAAGAGGTAGCTGAAGAGTGGTGGTTTTTCCCTGTATCCTGATTTTCAG
AAAGGGCTTTAGTCTCTGAGCTGTGGCTAGTAGCTGGCTGGCTGACCAGGGGACGGGGGTCTAATAGGGTGTCTGACCATAGGACACCTC
TCGTGTTTGGCCTTCCCTTTCTTGTGTGTTTGTGTGTGTGTGTGCACGTGCACGTGCACACACATGTACACACACAAATCTGTATCCCCA
GGAGTGCCTCCTGCAGTCACTGGGGGCTCTTCCGTGGTGCACCATCCCATGAGAGCAGATCAGAGGGCTGTGGTCAGGACTTCCTCCCGA
GCTGCCCTCCCTCCCTGGGATGAGTTTCCTCTCCACCTGCTCCAAGGTGCCTTACGAGGTGCAGCTCTTCACCTGGCCACATGGCATCCA
TCACCGTGTTGAGAAATGGTGGGACGTTGGCTGGATATTGTGTGCTATGAATCTGATTTGTCCAAATCTGGACCTCAGCCAAGCCACCTG
TGGTGGAACCTTGCAAGTCAAGGTCATGAACAAATTTCTTGTAACTATTGGAAATAAACTAATGAGGTAGAACTGTCATATCCAAATGGA
AGAGGTGGTTGGTACTGTTACTTCCTTTTGCTGTCAGAGGGTTGTTGACAATGGCAAGGGGGGATGTTAGTGAGATCCAGGTGGTGGTGG
CTTCTTGGTCCACTCAGCTTGCACACATGCAAGAGGAGGGTCTGTGGCCCCTCAGCCGTGCTGGTGGCCTCCTTCCTCAAGCTTTAACTT
GTGCCCTCCCTGGCAACAGGGAGTCATGGGTTAATGTCACCTGTCATGCCTCTTTCTTCAGGGAAAATATTAAAAGGCTCAAATCCAAGC
TGTGACTTCCCTTAGACAGTGTAAGCCTGTAGGGTGCAGCCCCAAGTTTATGTCCAAAGGCTGCCTCAGAACCCTGGAGGGAGCAGCGCC
CAGCTGGCAGCTCACTCTGCCCTTGCAGTTCACTGGCCTTTTCGCAGCCAGGCTAAGATAGGCAGTGCAAGGAGCTTCCCACTGGCCAGA
GCAGCTGCCTTGTAGAATGTGGGGCTGGCTTTTAGAAGTTTCACACGCTTGCAGCTAAGAGTGCAGAGCTCTCTGTTTTACTTCGTGAAA
CATTAGCAGCTCTGAGGGGCTTGGCTTTTGGTAAGGGACTTATGGTCTGACTTGCCACAAGCACCTTGAGCTCCTGGGTTGGTTGGTGGT
TGGTTGGTTGGGTTGTTTTAAATTTGATTTTTCTTTTCCTGAAGTTTGTTAGAAGTCAGACCTATGCAAGGAAAACCATGGCCCACTTCA
GCAGCCATCCAGTGGGGGTGCTTAATCGGTGGTGGTAGGATTCATGGAAACGTTTTTTTGAAATGAAAGAGAAGATGATGTACTTACATT

>63011_63011_7_PBRM1-TMEM110_PBRM1_chr3_52584437_ENST00000410007_TMEM110_chr3_52889460_ENST00000355083_length(amino acids)=1793AA_BP=1550
MGSKRRRATSPSSSVSGDFDDGHHSVSTPGPSRKRRRLSNLPTVDPIAVCHELYNTIRDYKDEQGRLLCELFIRAPKRRNQPDYYEVVSQ
PIDLMKIQQKLKMEEYDDVNLLTADFQLLFNNAKSYYKPDSPEYKAACKLWDLYLRTRNEFVQKGEADDEDDDEDGQDNQGTVTEGSSPA
YLKEILEQLLEAIVVATNPSGRLISELFQKLPSKVQYPDYYAIIKEPIDLKTIAQRIQNGSYKSIHAMAKDIDLLAKNAKTYNEPGSQVF
KDANSIKKIFYMKKAEIEHHEMAKSSLRMRTPSNLAAARLTGPSHSKGSLGEERNPTSKYYRNKRAVQGGRLSAITMALQYGSESEEDAA
LAAARYEEGESEAESITSFMDVSNPFYQLYDTVRSCRNNQGQLIAEPFYHLPSKKKYPDYYQQIKMPISLQQIRTKLKNQEYETLDHLEC
DLNLMFENAKRYNVPNSAIYKRVLKLQQVMQAKKKELARRDDIEDGDSMISSATSDTGSAKRKSKKNIRKQRMKILFNVVLEAREPGSGR
RLCDLFMVKPSKKDYPDYYKIILEPMDLKIIEHNIRNDKYAGEEGMIEDMKLMFRNARHYNEEGSQVYNDAHILEKLLKEKRKELGPLPD
DDDMASPKLKLSRKSGISPKKSKYMTPMQQKLNEVYEAVKNYTDKRGRRLSAIFLRLPSRSELPDYYLTIKKPMDMEKIRSHMMANKYQD
IDSMVEDFVMMFNNACTYNEPESLIYKDALVLHKVLLETRRDLEGDEDSHVPNVTLLIQELIHNLFVSVMSHQDDEGRCYSDSLAEIPAV
DPNFPNKPPLTFDIIRKNVENNRYRRLDLFQEHMFEVLERARRMNRTDSEIYEDAVELQQFFIKIRDELCKNGEILLSPALSYTTKHLHN
DVEKERKEKLPKEIEEDKLKREEEKREAEKSEDSSGAAGLSGLHRTYSQDCSFKNSMYHVGDYVYVEPAEANLQPHIVCIERLWEDSAEK
EVFKSDYYNKVPVSKILGKCVVMFVKEYFKLCPENFRDEDVFVCESRYSAKTKSFKKIKLWTMPISSVRFVPRDVPLPVVRVASVFANAD
KGDDEKNTDNSEDSRAEDNFNLEKEKEDVPVEMSNGEPGCHYFEQLHYNDMWLKVGDCVFIKSHGLVRPRVGRIEKVWVRDGAAYFYGPI
FIHPEETEHEPTKMFYKKEVFLSNLEETCPMTCILGKCAVLSFKDFLSCRPTEIPENDILLCESRYNESDKQMKKFKGLKRFSLSAKVVD
DEIYYFRKPIVPQKEPSPLLEKKIQLLEAKFAELEGGDDDIEEMGEEDSEVIEPPSLPQLQTPLASELDLMPYTPPQSTPKSAKGSAKKE
GSKRKINMSGYILFSSEMRAVIKAQHPDYSFGELSRLVGTEWRNLETAKKAEYEGMMGGYPPGLPPLQGPVDGLVSMGSMQPLHPGGPPP
HHLPPGVPGLPGIPPPGVMNQGVAPMVGTPAPGGSPYGQQVGVLGPPGQQAPPPYPGPHPAGPPVIQQPTTPMFVAPPPKTQRLLHSEAY
LKYIEGLSAESNSISKWDQTLAVKRFREPKHERRPWRIWFLDTSKQAIGMLFIHFANVYLADLTEEDPCSLYLINFLLDATVGMLLIYVG
VRAVSVLVEWQQWESLRFGEYGDPLQCGAWVGQCALYIVIMIFEKSVVFIVLLILQWKKVALLNPIENPDLKLAIVMLIVPFFVNALMFW

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Fusion Gene PPI Analysis for PBRM1-TMEM110


check button Go to ChiPPI (Chimeric Protein-Protein interactions) to see the chimeric PPI interaction in

ChiPPI page.


check button Protein-protein interactors with each fusion partner protein in wild-type (BIOGRID-3.4.160)
HgeneHgene's interactorsTgeneTgene's interactors


check button - Retained PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenStill interaction with


check button - Lost PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


check button - Retained PPIs, but lost function due to frame-shift fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


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Related Drugs for PBRM1-TMEM110


check button Drugs targeting genes involved in this fusion gene.
(DrugBank Version 5.1.8 2021-05-08)
PartnerGeneUniProtAccDrugBank IDDrug nameDrug activityDrug typeDrug status

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Related Diseases for PBRM1-TMEM110


check button Diseases associated with fusion partners.
(DisGeNet 4.0)
PartnerGeneDisease IDDisease name# pubmedsSource