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Center for Computational Systems Medicine
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Fusion Gene Summary

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Fusion Gene ORF analysis

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Fusion Genomic Features

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Fusion Protein Features

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Fusion Gene Sequence

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Fusion Gene PPI analysis

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Related Drugs

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Related Diseases

Fusion gene:PCBD2-SKP1 (FusionGDB2 ID:63092)

Fusion Gene Summary for PCBD2-SKP1

check button Fusion gene summary
Fusion gene informationFusion gene name: PCBD2-SKP1
Fusion gene ID: 63092
HgeneTgene
Gene symbol

PCBD2

SKP1

Gene ID

84105

6500

Gene namepterin-4 alpha-carbinolamine dehydratase 2S-phase kinase associated protein 1
SynonymsDCOH2|DCOHM|PHS2EMC19|OCP-II|OCP2|SKP1A|TCEB1L|p19A
Cytomap

5q31.1

5q31.1

Type of geneprotein-codingprotein-coding
Descriptionpterin-4-alpha-carbinolamine dehydratase 24-alpha-hydroxy-tetrahydropterin dehydratase 26-pyruvoyl-tetrahydropterin synthase/dimerization cofactor of hepatocyte nuclear factor 1 alpha (TCF1) 2DcoH-like protein DCoHmHNF-1-alpha dimerization cofactorPHS-phase kinase-associated protein 1OCP-2RNA polymerase II elongation factor-like protein OCP2SIIIcyclin A/CDK2-associated p19cyclin-A/CDK2-associated protein p19organ of Corti protein 2organ of Corti protein IIp19skp1transcription elongation fact
Modification date2020031320200327
UniProtAcc..
Ensembl transtripts involved in fusion geneENST00000510013, ENST00000254908, 
ENST00000512783, 		ENST00000353411, 
ENST00000517625, ENST00000521216, 
ENST00000522552, ENST00000522855, 
Fusion gene scores* DoF score15 X 64 X 7=672016 X 9 X 7=1008
# samples 4017
** MAII scorelog2(40/6720*10)=-4.0703893278914
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0		log2(17/1008*10)=-2.56788898736222
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0
Context

PubMed: PCBD2 [Title/Abstract] AND SKP1 [Title/Abstract] AND fusion [Title/Abstract]

Most frequent breakpointPCBD2(134246156)-SKP1(133509713), # samples:1
SKP1(133512545)-PCBD2(134294729), # samples:1
Anticipated loss of major functional domain due to fusion event.
* DoF score (Degree of Frequency) = # partners X # break points X # cancer types
** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10)

check button Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez
PartnerGeneGO IDGO termPubMed ID
HgenePCBD2

GO:0045893

positive regulation of transcription, DNA-templated

11980910

TgeneSKP1

GO:0016567

protein ubiquitination

15103331

TgeneSKP1

GO:0031146

SCF-dependent proteasomal ubiquitin-dependent protein catabolic process

15103331|20347421

TgeneSKP1

GO:0035518

histone H2A monoubiquitination

16943429


check buttonFusion gene breakpoints across PCBD2 (5'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.
all structure

check buttonFusion gene breakpoints across SKP1 (3'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.
all structure

check button Fusion gene information from two resources (ChiTars 5.0 and ChimerDB 4.0)
* All genome coordinats were lifted-over on hg19.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
SourceDiseaseSampleHgeneHchrHbpHstrandTgeneTchrTbpTstrand
ChimerDB4Non-Cancer215NPCBD2chr5

134246156

+SKP1chr5

133509713

-


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Fusion Gene ORF analysis for PCBD2-SKP1

check button Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
ORFHenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrand
3UTR-3CDSENST00000510013ENST00000353411PCBD2chr5

134246156

+SKP1chr5

133509713

-
3UTR-3CDSENST00000510013ENST00000517625PCBD2chr5

134246156

+SKP1chr5

133509713

-
3UTR-3CDSENST00000510013ENST00000521216PCBD2chr5

134246156

+SKP1chr5

133509713

-
3UTR-3CDSENST00000510013ENST00000522552PCBD2chr5

134246156

+SKP1chr5

133509713

-
3UTR-3CDSENST00000510013ENST00000522855PCBD2chr5

134246156

+SKP1chr5

133509713

-
In-frameENST00000254908ENST00000353411PCBD2chr5

134246156

+SKP1chr5

133509713

-
In-frameENST00000254908ENST00000517625PCBD2chr5

134246156

+SKP1chr5

133509713

-
In-frameENST00000254908ENST00000521216PCBD2chr5

134246156

+SKP1chr5

133509713

-
In-frameENST00000254908ENST00000522552PCBD2chr5

134246156

+SKP1chr5

133509713

-
In-frameENST00000254908ENST00000522855PCBD2chr5

134246156

+SKP1chr5

133509713

-
In-frameENST00000512783ENST00000353411PCBD2chr5

134246156

+SKP1chr5

133509713

-
In-frameENST00000512783ENST00000517625PCBD2chr5

134246156

+SKP1chr5

133509713

-
In-frameENST00000512783ENST00000521216PCBD2chr5

134246156

+SKP1chr5

133509713

-
In-frameENST00000512783ENST00000522552PCBD2chr5

134246156

+SKP1chr5

133509713

-
In-frameENST00000512783ENST00000522855PCBD2chr5

134246156

+SKP1chr5

133509713

-

check buttonORFfinder result based on the fusion transcript sequence of in-frame fusion genes.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandSeq length
(transcript)		BP loci
(transcript)		Predicted start
(transcript)		Predicted stop
(transcript)		Seq length
(amino acids)
ENST00000254908PCBD2chr5134246156+ENST00000353411SKP1chr5133509713-9733450159941260
ENST00000254908PCBD2chr5134246156+ENST00000522552SKP1chr5133509713-2023450159932257
ENST00000254908PCBD2chr5134246156+ENST00000521216SKP1chr5133509713-1283450159941260
ENST00000254908PCBD2chr5134246156+ENST00000517625SKP1chr5133509713-1167450159941260
ENST00000254908PCBD2chr5134246156+ENST00000522855SKP1chr5133509713-1103450159941260
ENST00000512783PCBD2chr5134246156+ENST00000353411SKP1chr5133509713-951923620727235
ENST00000512783PCBD2chr5134246156+ENST00000522552SKP1chr5133509713-180923620718232
ENST00000512783PCBD2chr5134246156+ENST00000521216SKP1chr5133509713-106923620727235
ENST00000512783PCBD2chr5134246156+ENST00000517625SKP1chr5133509713-95323620727235
ENST00000512783PCBD2chr5134246156+ENST00000522855SKP1chr5133509713-88923620727235

check buttonDeepORF prediction of the coding potential based on the fusion transcript sequence of in-frame fusion genes. DeepORF is a coding potential classifier based on convolutional neural network by comparing the real Ribo-seq data. If the no-coding score < 0.5 and coding score > 0.5, then the in-frame fusion transcript is predicted as being likely translated.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandNo-coding scoreCoding score
ENST00000254908ENST00000353411PCBD2chr5134246156+SKP1chr5133509713-0.0004532590.9995467
ENST00000254908ENST00000522552PCBD2chr5134246156+SKP1chr5133509713-0.0004042370.9995958
ENST00000254908ENST00000521216PCBD2chr5134246156+SKP1chr5133509713-0.000650880.99934906
ENST00000254908ENST00000517625PCBD2chr5134246156+SKP1chr5133509713-0.0009623970.9990376
ENST00000254908ENST00000522855PCBD2chr5134246156+SKP1chr5133509713-0.0011529120.9988471
ENST00000512783ENST00000353411PCBD2chr5134246156+SKP1chr5133509713-0.000437990.99956197
ENST00000512783ENST00000522552PCBD2chr5134246156+SKP1chr5133509713-0.0002589190.999741
ENST00000512783ENST00000521216PCBD2chr5134246156+SKP1chr5133509713-0.0004594480.99954057
ENST00000512783ENST00000517625PCBD2chr5134246156+SKP1chr5133509713-0.000488190.99951184
ENST00000512783ENST00000522855PCBD2chr5134246156+SKP1chr5133509713-0.0006048310.99939513

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Fusion Genomic Features for PCBD2-SKP1


check buttonFusionAI prediction of the potential fusion gene breakpoint based on the pre-mature RNA sequence context (+/- 5kb of individual partner genes, total 20kb length sequence). FusionAI is a fusion gene breakpoint classifier based on convolutional neural network by comparing the fusion positive and negative sequence context of ~ 20K fusion gene data. From here, we can have the relative potentency of the 20K genomic sequence how individual sequnce will be likely used as the gene fusion breakpoints.
HgeneHchrHbpHstrandTgeneTchrTbpTstrand1-pp (fusion gene breakpoint)

check buttonDistribution of 44 human genomic features loci across 20kb length fusion breakpoint regions. We integrated a total of 44 different types of human genomic feature loci information across five big categories including virus integration sites, repeats, structural variants, chromatin states, and gene expression regulation. More details are in help page.
genomic feature

check buttonDistribution of 44 human genomic features loci across 20kb length fusion breakpoint regions that are ovelapped with the top 1% feature importance score regions. More details are in help page.

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Fusion Protein Features for PCBD2-SKP1


check button Four levels of functional features of fusion genes
Go to FGviewer search page for the most frequent breakpoint (https://ccsmweb.uth.edu/FGviewer/chr5:134246156/chr5:133509713)
- FGviewer provides the online visualization of the retention search of the protein functional features across DNA, RNA, protein, and pathological levels.
- How to search
1. Put your fusion gene symbol.
2. Press the tab key until there will be shown the breakpoint information filled.
4. Go down and press 'Search' tab twice.
4. Go down to have the hyperlink of the search result.
5. Click the hyperlink.
6. See the FGviewer result for your fusion gene.
FGviewer

check buttonMain function of each fusion partner protein. (from UniProt)
HgeneTgene
..
FUNCTION: Transcriptional activator which is required for calcium-dependent dendritic growth and branching in cortical neurons. Recruits CREB-binding protein (CREBBP) to nuclear bodies. Component of the CREST-BRG1 complex, a multiprotein complex that regulates promoter activation by orchestrating a calcium-dependent release of a repressor complex and a recruitment of an activator complex. In resting neurons, transcription of the c-FOS promoter is inhibited by BRG1-dependent recruitment of a phospho-RB1-HDAC1 repressor complex. Upon calcium influx, RB1 is dephosphorylated by calcineurin, which leads to release of the repressor complex. At the same time, there is increased recruitment of CREBBP to the promoter by a CREST-dependent mechanism, which leads to transcriptional activation. The CREST-BRG1 complex also binds to the NR2B promoter, and activity-dependent induction of NR2B expression involves a release of HDAC1 and recruitment of CREBBP (By similarity). {ECO:0000250}.FUNCTION: Transcriptional activator which is required for calcium-dependent dendritic growth and branching in cortical neurons. Recruits CREB-binding protein (CREBBP) to nuclear bodies. Component of the CREST-BRG1 complex, a multiprotein complex that regulates promoter activation by orchestrating a calcium-dependent release of a repressor complex and a recruitment of an activator complex. In resting neurons, transcription of the c-FOS promoter is inhibited by BRG1-dependent recruitment of a phospho-RB1-HDAC1 repressor complex. Upon calcium influx, RB1 is dephosphorylated by calcineurin, which leads to release of the repressor complex. At the same time, there is increased recruitment of CREBBP to the promoter by a CREST-dependent mechanism, which leads to transcriptional activation. The CREST-BRG1 complex also binds to the NR2B promoter, and activity-dependent induction of NR2B expression involves a release of HDAC1 and recruitment of CREBBP (By similarity). {ECO:0000250}.

check buttonRetention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at

download page


* Minus value of BPloci means that the break pointn is located before the CDS.
- In-frame and retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note

- In-frame and not-retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note


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Fusion Gene Sequence for PCBD2-SKP1


check button For in-frame fusion transcripts, we provide the fusion transcript sequences and fusion amino acid sequences. To have fusion amino acid sequence, we ran ORFfinder and chose the longest ORF among the all predicted ones.
>63092_63092_1_PCBD2-SKP1_PCBD2_chr5_134246156_ENST00000254908_SKP1_chr5_133509713_ENST00000353411_length(transcript)=9733nt_BP=450nt
AGAGTCCACCTGGCGGCCAAGGGCGCTGGCGACCGCTGAAGCTCCTGGGGGTGTTCGGGGTCCGGGCTGCGCCTGTGCCCGCGGGAAGGC
TGGGCGCTTCCCACACACAGACCCCGCTCCGGGCCAGCCCCGCAGGGAGACTACCAGGGCTGGCGGTAGCTGGGCGTGGTCGGGTCGGGG
GCGGCTGTGGGCGGCCGGCAGGCAGCGCGCGGGGCAGCCCTCGGCAGACGGCCAATGGCGGCGGTGCTCGGGGCGCTCGGGGCGACGCGG
CGCTTGTTGGCGGCGCTGCGAGGCCAGAGCCTAGGGCTAGCGGCCATGTCATCAGGTACTCACAGGTTGACTGCAGAGGAGAGGAACCAA
GCTATACTTGACCTTAAAGCAGCAGGATGGTCGGAATTAAGTGAGAGAGATGCCATCTACAAAGAATTCTCCTTCCACAATTTTAATCAG
ATGCCTTCAATTAAGTTGCAGAGTTCTGATGGAGAGATATTTGAAGTTGATGTGGAAATTGCCAAACAATCTGTGACTATTAAGACCATG
TTGGAAGATTTGGGAATGGATGATGAAGGAGATGATGACCCAGTTCCTCTACCAAATGTGAATGCAGCAATATTAAAAAAGGTCATTCAG
TGGTGCACCCACCACAAGGATGACCCTCCTCCTCCTGAAGATGATGAGAACAAAGAAAAGCGAACAGATGATATCCCTGTTTGGGACCAA
GAATTCCTGAAAGTTGACCAAGGAACACTTTTTGAACTCATTCTGGCTGCAAACTACTTAGACATCAAAGGTTTGCTTGATGTTACATGC
AAGACTGTTGCCAATATGATCAAGGGGAAAACTCCTGAGGAGATTCGCAAGACCTTCAATATCAAAAATGACTTTACTGAAGAGGAGGAA
GCCCAGGTACGCAAAGAGAACCAGTGGTGTGAAGAGAAGTGAAATGTTGTGCCTGACACTGTAACACTGTAAGGATTGTTCCAAATACTA
GTTGCACTGCTCTGTTTATAATTGTTAATATTAGACAAACAGTAGACAAATGCAGCAGCAAGTCAATTGTATTAGCAGAATATTGTCCTC
ATTGCATGTGTAGTTTGAGCACAGATCCCAAACCTTACGGCCAAGTTTCTTCTAGTATGATGGAAAGTTTCTTTTTTCTTTGCTCTGAAT
AAAACTGAACTGTGGGTTCTCTATAAGTGGCATTTTGGGCTTTCCCTCTTTTTTGTAAAGCAATGTCTGCCTAGTTTATTGTCCAGTTAA
CTTTAGTGACCTTTTAAAAGTTGGCATTGTAAATAAAACAACTTGCAAAAAAGTTTTCTGGAATAGAATTAACAAAATATTATCTTTATT
CATGAGTTGGAAACTGGAAAAAGGCTTCTTGAAGTAAATGTTCTGAGTGGAGCTACTAGGATGTCTTCCAGCCTCCTGCAGTCAAGGAGT
ACCACTGTATTGATTAGCCTGTATGTAGCAGGGCTCCCTTCATTGCATCTGAGGACTTGTTTTCTTTTTCTTTATTTTTAATCCTCTTAG
TTTTAAATATATTGCCTAGAGACTCAGTTACTACCCAGTTTGTGGTTTTTTGGGAGAAATGTAACTGGACAGTTAGCTTTTCAATTAAAA
AGACACTTAACCCATGTGGGATGTCATCTTTTTATAATTAGTGTTCCCATGTGGAGAAAATTATTCACACTACTTGCATGTAAAGAATAA
TTTAACTTTTAACATTAAAATATGTGGTAAAACCCAGAAAGCATCCATCATGAATGCAAGATACTTTCAATAAAAAGTAAGTTATATAGT
AGGTAGTTAAGTTTGCTTTTGTGGACTTAAATGTGTCTCTTCACTTAAATGGGTTGAATGTGTATATATTTGTTCAGCTTGAAAAGACTT
AGTTTATATCCTAGCTCACTGGAGGCTGCTGACATAACCATAACTTCTGTCCCTTCTAATTGTCATTTATATGCCTAACTGGAGCTAGTA
CTTTAATTCTTAACACAAAATTACTCTGCCATTGTTTCCAGCTTCCCTCCTACAATAGAATGAAGTTTTTTTGATGGCTTGAGATGGCTC
ACAAATTTTGATTTTTTTTTCTTCCTTGTGCTCCCTTTTTTTCTCCTTGCTTTTCCAGTTAACATCTATATTCACATGTAATCTTGTTTT
CTCTTCACATTCACTGAGTTGTTCAGGCTCAGATCATCCCTTGACAGTAGTTTGCCTTCATCTCACCTTTCATTTGTCCCAAATTCACCT
TATTTAATAAAGTCCCATATGTTGTCTCACTTAATTCCAATTTGTTGTCTGTACCAGAGATAGGAAACTATAATGTGTGGGTCAAATCAG
GCCCATAGCCTGTTTTTGTAGTCTTTGAGCTAAAAATGGTTTTTACGTTGTAAAGAGTTATTTAAAATTCTCTCTCTCTCTCTCTCTCTC
TCTCAGGAGATAAGCTTGTTTTCTGTTTGTCCTGGTTTTAGTGGGGAAGGTAGCGGTGTATAGTCCTAGCTGAATTGTCTCATCTACCAA
TTCCTGCTATTATAAGATCAACTTCTGCAAAAACCTTATCCACCTCAAGTATCCTTAGCAGCTGGGCATGGTGGCTTATGCCTGTAATCT
CAACATTTTGGGAGGACAAGACAGGAGGATCGTTTGAGCCCAGGAGTTCAAGACCAGCCTGGGCAACACAGAAAGTCCCTGTCTCTCCAA
AAAAAAAAAAAAAAATTAGCAGTCATATGGTGCATGCCTATAATCCCAACTACTTGAGAGGCTGAGGTGGGAAGATGGCTTGAGCCTGAG
AGGTCGAGGCTGCAGTGAGCTGGCATTGCACCACTGCACTCCAGTCTAGGCAATAGAGCGAGACCTTGTCTCAAAAACAAACCAGAAGTA
TCCTTAGCAGTATTATGACAAACAAATCTTCACTGAAGGTCCAGGATTACTGCCATATGCCATGTTTAACTTGTAAAGGAAGTATCACCT
TCTAAGAAACTGGAGCTTGTTATTACCACTTGATCTGTATAATACTCAGCAGTAGTTAGAATTATATGAGTAAATAACGTCACTATCCGT
ATTTAAAGGATAATGAGATCTTTCAGAAAGATTGGATGGACAGACAATATAGTAGTAATTTAAATTTTTGTTTCCTGACTTTCTGTAGTC
CCTAAACAAACAACAAAAAATCCTAGTAATCTTAAACTTTTACATTAATAGAGATCCAAGAGAAAATAAGCCATTTTTCACCATTGTGGA
CCCAAATAAATCATAGACATGGTATTAAGAAGCCCTTTTCAGTCTGGTTGCAGTATTATTTTCCTACCTTTCTTTTTCCTGTTCCCTGCT
GTATGCCCACTATTCCTTTAATATATCTACTAGAACTTTTCTAGGCTTTCACCTGGAGTGAGTGGTCCTTTCTCATTATCACAGTAGCCA
AACCTCAGTCTTCAAAACTCCACTCATTTCTGGCTACTCTCTTACTTCCCAACTATTCTTCTAAACTAATATTGTGGCATTAAGTCATAC
CTTGAGGCTGGAGTTTTAGTGTCTTCATGGCCTTGGGCAAGTTGGAAATAGGTACTACGGTTTTATAGATCTAGTGCAGTCTGCTTTATA
TTAGTTCCAGAACTTCATTGGAAGTCACTTGACAGCAGGATTTAACTTGTATTTAGCAGCACTACTCCATGAATTTCAGTATAAGTAACA
GAAGTGAAAAGTCCTTGTGAAATGCAGGTACAGGGCATAATGAAAACAAGAAGAGTAGTTTTAATGCATGAGAGGGGAGAGCTTGATAAT
AGCTGATAATAGCCTTGGTTTGGAGAGTGGTTACTGATGAATTATGAAGACTTTCTCTAATTACTGTTATAGTAGTAAAGGAAAGAAAAC
CCTTGTTGATAAAGTAAACTTAGGGATTAATTAGGAAATGCCTTTTATTTCACCAGGAAAGAGAATGAGAGGAAGAAGGTATTTGGCAGA
TTTGGGTGATTGAAGGATGTTTGTCGGTTTCCTCTGTAAACAACATGCTGCTTTCTGCAGTGTGCTGCTTTTAATGATGAAGTCCTTTCA
AGGACTCCATGGCAGTCCTTTGGCTTCTCACCTTTTCATTGATTATGTCACTTGTGATCTAAAAGTAAACCAAAACCTTCCTGAATGTTA
GCTTATTATTTTCTCCTTAACATTGTCATAGGCTAAAGATGTGCCCCCTCAAATTCTAATAATTTTTTTTTTTTTTTTTTTTTTTTTGAG
ACAGAGTCTCACTCTGTCGCCCAGACTGGAATGCAGTGGTGCGATCTCAGCTCACTGCAACCTCCGCCTCCTGGGTTCAAGTGATTCTCC
TGCCTCAGCCTCCCGAGTAGCTGGGATTACAGGCACATGCCACCATGCCTGGCTAATTTTTTTGTGTTTTTATTAGAGATGGAGTTTTAC
CATATTGGCCAGGCTGGTCTTGAACTCCTGACCTTGTGATCCGCCCGCCTTAGCCTCCGAAAGTGCTGAGGTTACACGTGTGACCCACCG
CACACGGCCCTAATAATTCTTAAGTTGTAGAAGCAAGTTACTCTTTTGAAGTGCCATGTGTTAGCTTGCCTTAATCTATTCTTGGTATAC
AAAATAGATACTGCTTTACAGTTCTTATATTTTCTCAGAGATTCACAAAATCATCCTGTAGCTCCCTGTGTGGGATTATAGCTGTGACTT
TTTACTCTACAACTGTCAGAATACACCAGCTCCTGGAATTAAGCAAGAACTATATTGTGACTTGGTTGGACAGGTAACTGCAGCCTTGTA
ACATGACATCATAGTAATGCTGAGCTTATCTTAAAACTAGCTGGGGAGGGAGGATAGTAACAGTGAGTCACTGTGGGCATCTCACTTAGG
GCAGGCAGATATTCCAAATCACATTGATTTTTCAGTTTACGTAAAAATTGACCAATCCTATGGGCTGTGTTCTGATCCCAACATAAATTT
TGTTTAAGTTAATTTGCCTAGGCTCTCAATAAGGCAGTTTGGGAATATAAGGTGATTTTCCACCAGAAAAGAGAAAATTGAGAGAGCAGC
AGACCTCTTGCTCTCAGCACCCTTTACAAGCTTAACTTTTGCTTGCCACCATTAGCTTTTGAAGATTTTTTTTAACTGCTCCTTGCAGAG
CAGGACTACCCCATAGGCAGTGTGCCCAGAGTAGCCCGAAGAGCTTTTTGATTCTTCTTTTAAGAGACAAGGTCTCACCTCTGCCCCCCA
GGCTGGAGTGCAGTGATGTGATCACAGCTCATTGCAGCCTCGAACTCTTGGGCTCCAACAGTCCTCCTGCCTCAGCCTCCTGAATAGCTA
GGACTACATGTGTGTGCTACCATGCCTTGCTAGTTTTTGTTTTTTTAAATTGATTTTTATAGAGATGAGGTCTCCTCATGTTGCCCAGGC
TGTTTTCGAATTCCTGGGCTCAAGATCCTCCTGCCTCAACCTCCCAAAGTGCTGGTATTACAGATGTGAGCCACAGCACCCACCAATTTT
TCCTTTTCTAAAGCTCAGTGTACATTCTGGTAGGAAGGAATCAACCAAGTAAATGTTCTCCCTACAAAGTTGTTTGAGGATTTGAAAAGT
TAATCTTCAATTATCTGGATTTGAAACCAGTCTATAACTTTTTAAGCTAGGAAGAAGTCAAGAATAAGAAGATTGCAAGCAAAGGGAAAG
CTTACAAAATGGCTGAATCCTTAAAGTGTAGCTCCTGGCTTCTCCTTGGTAGGAAGCATTAGACATGGTTTCCCTCTAGGGAGCTGGGAG
CTTTTGGTGTAGTTCAGGAGAGAAGGCATAAATACTGCTGGGAGGGAGTGGATAACTCTAATAAAAATGTTCCTGGGCTGGGCACGGTGG
CTCACGCCTGTAATCCCAACATTTTCAGAGGCTGAGGTGTGCAGATCACGAGGTCAAGAGATCGAGACCATCCTGGCCAACATGGTGAAA
CCTCATCTCTACTAAAAATACAAAAATTAGCTGGGCGTGGTGGCACATGCCTGTAGTCCCAGCAACTCGGGAGGCTGAGGCAGGAGAACC
GCTTGAACCCGGGAGGCGGAAGTTGCAGTGAGCCGACATCACGCCACTGACTGCAGTCCAGCCTGGCGACAGAGCGAGACTCCGTTTCAA
AAAAAAAAAGTTTCTGGACAGAACAGATTAATGAGCCAATGGGGGGCTACAGAGCTGAAAGGTGCTACGAAAGGTTTTGTAAAGTGAAAC
TAATTTGGTTTCAAGAATCAAGTTGGATTTGTTTGGGGGTGGACAGATGCCAAAGTGAGGAAAAAGCAGTGCACAGTCAGGAACTAACAG
CAGAAGGTTGGGTGTTGGTACATTTCCCTGAGAATATAGACTAAAGAGAAATTAGGGCAGGATTAGTCACAGTACTTTGCTGACACTCAG
TAGTATTTTATCAGCATTTATTCATCAGACCCACATTAGGCAGGGCAATTTTTGAGTGAGCTAAATTCTAATTTTTTTAATTTTAATTTT
TATTTATTTATTTTTTGGCTGTTCAACTAAACCAGTCTTTTGAATGTTGGGGGTTTTACAGTTAGAGTCCTGATGACTTTTTCTTGTTTA
CTGTTGTTAAAAATCACTACCTCCAGTGGTCACAGAGAATGAGTAAGAGAACTGGCTGTGCATATCAAGATGAAGTATGGTGTAAGAAAT
ATTTCAGAGCATGTCCTTTGGCCCAAGATTGAGCCATTTGGACACCTAAGCAGGATTGGCTGAATGTTATCCTTTCTGCTGAGGCATCAG
TGGAGATGATCATTAGTGGTGGCCGAAAAGTGTTGTCGAAGGTGCTCTTGCTTGACACACTTCCAATGCGGGACATAGTTTGAGTGATAG
ATGGCTAATTCATTGATAATGTACTTGTTGCCTTGCAGTCTTGTGTACTGCTGGCTACCTCTGGTCTGTGTGCCAGTATTGAGCAGCATT
CTATGGGAGGAATGTAGTTGCTCATAACAGTGTCTGCTTCCACATCTGTAGTTCTTGCGACCTTCTGATATCTGTCAACTTTAAATTTTC
TGGAAGTATTTAAGTATATTCAGACCTTCTGATATCTCTTAACTTCAAATTTTCAACCTGCTATATAGCAGCCTCTTATTGCACACTGAG
GATCAGCTTATTTCCTTAAAGTGCTCTCACTTTGAATACCTCCCACCTATCTGGTGAAAATTCTTATTTGTCCTTTCTTTCCTGAATGTA
CCATTTCACAACCTCTAACTGCCTTCTTCAGTTGCTTTGCAGATTTTTCTGTTCCAGGAAGCTTACGGAAAGGGGTGGGAAAATAGAGAA
GCTGTACTCTATCCTCAAGTACTCAAGCAGGGTTTCCAGAGTGGCTTTGTAAAAATTTTTATTTATTTATTTATTTATTTTTGGTGAGTG
GAACCTGGCTTTTCCTCTTCCCTCCCCAAGCCCCACCCCGCTTCCTGACATTGCACATGCCTGAAAGAACTAGGCTTCAGATAAAAGAAT
GAGAACACTTGAATGAAAAAGGAAGACTTGGTCCAGAGCCCCTGGTGAATATGAAAGAAGTATTGGCCTGGACTATCTCCCGCATAATTC
ACAGCTGCTATCTTGTCTTCAGAAGTGAAACATCCCTTACCAATAGTGACCTAACTTGTGAGGACTGCTTGTGATAGTATAGTTCCCACC
CCCAGGACATAAGTTTTCCCTTTCCAGTTAACATGCCTAATCCCATGCTATCTTTAAGAGCTTGAAAATCCTTCCTGACCTGAGCTAGGC
TTTTATTCTAAGGGACTGTGTATGTGAACATCCCCACCATCTATGTTTCCTGTTTTCAAACTCGGTGCCGTTTTGAGTATTTTCAGATGC
TCACTGCCAGTAATGGTTTGTTAGTAGCTCCAAACTATTAGAGAAGAGCTCAGGAGTCAGAATTTGAAAGATGCCCATAGGGTGATTTGA
GATTTGGAACAAGGTTATCACAATAAGTTGGGATTGGGGGAGTTGACACAACCAGGGTCTGCTTGGGTGGGCAGCTGTTTCAGAAACCCT
TGGTGAACTCTTAAAGCCCTGAAGAGCTTAAAAAATGCTCTGAAGAGATCTGAGAGTCGCAGTTAAGGACTCTCAAAGAACCTCAAAGAA
AAGCCAACTTAGCCTTTTTATACAATTAACTAGATTTGGGTCTTAAATTCTACTTTGACATATAGGCCTAAGAGGTAGTTTAACATGGCC
TTGTTACCCTTACCCCTTCTGTTCTGTGCTGTTTTCTGAGAAACGGATGCAGGAACTGATTCCCTTTCTTCCTCTCTGGAACAGGATATA
AAGAACCCTTCCGCTTCCCTTTACTTGTGGCCTTCCTGGCCAGGCTTATGTATACTGAACAAAGCTAGGGTGCAGTGCTTCTGAGCTAGC
TGTTAGGGGTCCACAGCCAGAAGGAATGGGAGACCACAGGAGCCATTCAAAAGATAATTACATGTCAGAAGAGAGTCCATCCATGGGGTT
CTGTTAAAGTAGACACCTTCACGTTGGGAGACATAGGCTTTGTCTGCTTGCTGGGCTGAACCCTCACCATATCCACAGAGAACAAAATGG
GGAGCAGCTGTACCAGGGGAGGGATGAACGTCTTTCACCCAAGTTGCCAGTCTGCTAGTTGTCTGGAAATGTTCAAGGGAGGCTAAGGTA
TCTTGTCTTATGATGTCTCAGGAAACAGGGTTGGTTCTCAGCTGGCAGTGAAGGGGGACTGGTGTGGTATTAGCAGTTGAACTTGAGGTT
GCAATCTCAAGTCACCCTCTGGCCTCGCAGGAATGCACCAGGGTGATTTGGGAGGATCTGAGTTTCCTTTATGAAGTCAGATTAAAAAAA
AAAAAAGCTGATCTGATTTAAACAGAGTTGCCAAAGACTTCCCCGCCAATACACAAAGACTGCATTGTTCAGGTACCCTGTGTACTCTAA
GTGAGACACCAAATCAGATGCAGCAACCTGGTCTTGCATAAGCCCTGGTTAGAATGTAGGTTTTTTAAACAACTAGGCCAGTAGCCAGAA
CAGAATTCTTTAAAATGGGACAGATGTCCAGAGAATGGCTAGTGTCCTCTAGCACTCTCTCAGAAGCAAAAGCAAGTCTGGGGTTACAAC
TTCCAGTGGCCTACTTTAAATAGACGCTGTTCTGGAAAATGACTTTATACTTTAAACACAAAATCCAAAAAATAGAACTCAGTGGAGTGA
CAATGACAATGCATGATGGTGGCCCAGTGGCTGTCCCATGTGAAATACTTCTTGCCTGACATGTATCATCTACTTGTTGACTGACCTATT
GAGGTGCCTTCATGACACCTTTTACATTCATGATAGGTCTCAGGAAGACAGCAGTGTACTTGGTGGAAACTCATGTAAAAAGTGGGTTGT
AGGGAGCTAAACAGTGAGTACACATGGTATATGGATACGGAATGGAATAATAGACATTGGAGACTTCAAAAGGTGGGAGATGAAAGGGGG
ATGAGGTATGAAATCCTACCTGTTGAGTACAATGTACACTACTTACGTGCACAGTACACTGTTTGGGTGAGAGGCACACTAAAAGCCCGG
ACCTCACCGCTACCCAGTATGTTCATGTAACACAGCTGCACTTGTACCCCCTAAATGTATACAAATAATCTAAAAATAGCCCGGACCTCA
CCGCTACACAATATATTCATGTAACACAGCTGCATTTGTACCCCCTAAATGTATACAAATAATCTAAAAATAAAGTGGATATGGTGGCTG

>63092_63092_1_PCBD2-SKP1_PCBD2_chr5_134246156_ENST00000254908_SKP1_chr5_133509713_ENST00000353411_length(amino acids)=260AA_BP=97
MGVVGSGAAVGGRQAARGAALGRRPMAAVLGALGATRRLLAALRGQSLGLAAMSSGTHRLTAEERNQAILDLKAAGWSELSERDAIYKEF
SFHNFNQMPSIKLQSSDGEIFEVDVEIAKQSVTIKTMLEDLGMDDEGDDDPVPLPNVNAAILKKVIQWCTHHKDDPPPPEDDENKEKRTD

--------------------------------------------------------------
>63092_63092_2_PCBD2-SKP1_PCBD2_chr5_134246156_ENST00000254908_SKP1_chr5_133509713_ENST00000517625_length(transcript)=1167nt_BP=450nt
AGAGTCCACCTGGCGGCCAAGGGCGCTGGCGACCGCTGAAGCTCCTGGGGGTGTTCGGGGTCCGGGCTGCGCCTGTGCCCGCGGGAAGGC
TGGGCGCTTCCCACACACAGACCCCGCTCCGGGCCAGCCCCGCAGGGAGACTACCAGGGCTGGCGGTAGCTGGGCGTGGTCGGGTCGGGG
GCGGCTGTGGGCGGCCGGCAGGCAGCGCGCGGGGCAGCCCTCGGCAGACGGCCAATGGCGGCGGTGCTCGGGGCGCTCGGGGCGACGCGG
CGCTTGTTGGCGGCGCTGCGAGGCCAGAGCCTAGGGCTAGCGGCCATGTCATCAGGTACTCACAGGTTGACTGCAGAGGAGAGGAACCAA
GCTATACTTGACCTTAAAGCAGCAGGATGGTCGGAATTAAGTGAGAGAGATGCCATCTACAAAGAATTCTCCTTCCACAATTTTAATCAG
ATGCCTTCAATTAAGTTGCAGAGTTCTGATGGAGAGATATTTGAAGTTGATGTGGAAATTGCCAAACAATCTGTGACTATTAAGACCATG
TTGGAAGATTTGGGAATGGATGATGAAGGAGATGATGACCCAGTTCCTCTACCAAATGTGAATGCAGCAATATTAAAAAAGGTCATTCAG
TGGTGCACCCACCACAAGGATGACCCTCCTCCTCCTGAAGATGATGAGAACAAAGAAAAGCGAACAGATGATATCCCTGTTTGGGACCAA
GAATTCCTGAAAGTTGACCAAGGAACACTTTTTGAACTCATTCTGGCTGCAAACTACTTAGACATCAAAGGTTTGCTTGATGTTACATGC
AAGACTGTTGCCAATATGATCAAGGGGAAAACTCCTGAGGAGATTCGCAAGACCTTCAATATCAAAAATGACTTTACTGAAGAGGAGGAA
GCCCAGGTACGCAAAGAGAACCAGTGGTGTGAAGAGAAGTGAAATGTTGTGCCTGACACTGTAACACTGTAAGGATTGTTCCAAATACTA
GTTGCACTGCTCTGTTTATAATTGTTAATATTAGACAAACAGTAGACAAATGCAGCAGCAAGTCAATTGTATTAGCAGAATATTGTCCTC

>63092_63092_2_PCBD2-SKP1_PCBD2_chr5_134246156_ENST00000254908_SKP1_chr5_133509713_ENST00000517625_length(amino acids)=260AA_BP=97
MGVVGSGAAVGGRQAARGAALGRRPMAAVLGALGATRRLLAALRGQSLGLAAMSSGTHRLTAEERNQAILDLKAAGWSELSERDAIYKEF
SFHNFNQMPSIKLQSSDGEIFEVDVEIAKQSVTIKTMLEDLGMDDEGDDDPVPLPNVNAAILKKVIQWCTHHKDDPPPPEDDENKEKRTD

--------------------------------------------------------------
>63092_63092_3_PCBD2-SKP1_PCBD2_chr5_134246156_ENST00000254908_SKP1_chr5_133509713_ENST00000521216_length(transcript)=1283nt_BP=450nt
AGAGTCCACCTGGCGGCCAAGGGCGCTGGCGACCGCTGAAGCTCCTGGGGGTGTTCGGGGTCCGGGCTGCGCCTGTGCCCGCGGGAAGGC
TGGGCGCTTCCCACACACAGACCCCGCTCCGGGCCAGCCCCGCAGGGAGACTACCAGGGCTGGCGGTAGCTGGGCGTGGTCGGGTCGGGG
GCGGCTGTGGGCGGCCGGCAGGCAGCGCGCGGGGCAGCCCTCGGCAGACGGCCAATGGCGGCGGTGCTCGGGGCGCTCGGGGCGACGCGG
CGCTTGTTGGCGGCGCTGCGAGGCCAGAGCCTAGGGCTAGCGGCCATGTCATCAGGTACTCACAGGTTGACTGCAGAGGAGAGGAACCAA
GCTATACTTGACCTTAAAGCAGCAGGATGGTCGGAATTAAGTGAGAGAGATGCCATCTACAAAGAATTCTCCTTCCACAATTTTAATCAG
ATGCCTTCAATTAAGTTGCAGAGTTCTGATGGAGAGATATTTGAAGTTGATGTGGAAATTGCCAAACAATCTGTGACTATTAAGACCATG
TTGGAAGATTTGGGAATGGATGATGAAGGAGATGATGACCCAGTTCCTCTACCAAATGTGAATGCAGCAATATTAAAAAAGGTCATTCAG
TGGTGCACCCACCACAAGGATGACCCTCCTCCTCCTGAAGATGATGAGAACAAAGAAAAGCGAACAGATGATATCCCTGTTTGGGACCAA
GAATTCCTGAAATATACTTTAAGGAAAACAACTGTCTCTTTACAGGCTGCAAACTACTTAGACATCAAAGGTTTGCTTGATGTTACATGC
AAGACTGTTGCCAATATGATCAAGGGGAAAACTCCTGAGGAGATTCGCAAGACCTTCAATATCAAAAATGACTTTACTGAAGAGGAGGAA
GCCCAGGTACGCAAAGAGAACCAGTGGTGTGAAGAGAAGTGAAATGTTGTGCCTGACACTGTAACACTGTAAGGATTGTTCCAAATACTA
GTTGCACTGCTCTGTTTATAATTGTTAATATTAGACAAACAGTAGACAAATGCAGCAGCAAGTCAATTGTATTAGCAGAATATTGTCCTC
ATTGCATGTGTAGTTTGAGCACAGATCCCAAACCTTACGGCCAAGTTTCTTCTAGTATGATGGAAAGTTTCTTTTTTCTTTGCTCTGAAT
AAAACTGAACTGTGGGTTCTCTATAAGTGGCATTTTGGGCTTTCCCTCTTTTTTGTAAAGCAATGTCTGCCTAGTTTATTGTCCAGTTAA

>63092_63092_3_PCBD2-SKP1_PCBD2_chr5_134246156_ENST00000254908_SKP1_chr5_133509713_ENST00000521216_length(amino acids)=260AA_BP=97
MGVVGSGAAVGGRQAARGAALGRRPMAAVLGALGATRRLLAALRGQSLGLAAMSSGTHRLTAEERNQAILDLKAAGWSELSERDAIYKEF
SFHNFNQMPSIKLQSSDGEIFEVDVEIAKQSVTIKTMLEDLGMDDEGDDDPVPLPNVNAAILKKVIQWCTHHKDDPPPPEDDENKEKRTD

--------------------------------------------------------------
>63092_63092_4_PCBD2-SKP1_PCBD2_chr5_134246156_ENST00000254908_SKP1_chr5_133509713_ENST00000522552_length(transcript)=2023nt_BP=450nt
AGAGTCCACCTGGCGGCCAAGGGCGCTGGCGACCGCTGAAGCTCCTGGGGGTGTTCGGGGTCCGGGCTGCGCCTGTGCCCGCGGGAAGGC
TGGGCGCTTCCCACACACAGACCCCGCTCCGGGCCAGCCCCGCAGGGAGACTACCAGGGCTGGCGGTAGCTGGGCGTGGTCGGGTCGGGG
GCGGCTGTGGGCGGCCGGCAGGCAGCGCGCGGGGCAGCCCTCGGCAGACGGCCAATGGCGGCGGTGCTCGGGGCGCTCGGGGCGACGCGG
CGCTTGTTGGCGGCGCTGCGAGGCCAGAGCCTAGGGCTAGCGGCCATGTCATCAGGTACTCACAGGTTGACTGCAGAGGAGAGGAACCAA
GCTATACTTGACCTTAAAGCAGCAGGATGGTCGGAATTAAGTGAGAGAGATGCCATCTACAAAGAATTCTCCTTCCACAATTTTAATCAG
ATGCCTTCAATTAAGTTGCAGAGTTCTGATGGAGAGATATTTGAAGTTGATGTGGAAATTGCCAAACAATCTGTGACTATTAAGACCATG
TTGGAAGATTTGGGAATGGATGATGAAGGAGATGATGACCCAGTTCCTCTACCAAATGTGAATGCAGCAATATTAAAAAAGGTCATTCAG
TGGTGCACCCACCACAAGGATGACCCTCCTCCTCCTGAAGATGATGAGAACAAAGAAAAGCGAACAGATGATATCCCTGTTTGGGACCAA
GAATTCCTGAAAGTTGACCAAGGAACACTTTTTGAACTCATTCTGGCTGCAAACTACTTAGACATCAAAGGTTTGCTTGATGTTACATGC
AAGACTGTTGCCAATATGATCAAGGGGAAAACTCCTGAGGAGATTCGCAAGACCTTCAATATCAAAAATGACTTTACTGAAGAGGAGGAA
GCCCAGGTAGGTAGCACACAGTTTTGTCTTTGATCACATGCTCTTAAAAAGGGAGTAACACCTATAACATGCCAGCAAAAGAGGTGACTG
TATCAAGTAGTCTTGATACTTTAGGGATAATATGTACTTAATGTGTCTTAAACATACTCTTACTGTTCTGTCTTTATGAATCTGAACACT
TAGATGATACTGCATTTTAAGCATAAGAACAATTAGTTTTCAATGAGAAGAGCTCTTGTTAATGTATTAACAGTTACTAGTTTTGGCACC
TGCAACTTTCTGTATAGACCATACATATCTGACATCAGAAAAGCAGGCCCTAGAGAGAAGTATATACTAGGGTACTTTAGAGCAACTTAA
TGAGGGGAGGAAATGAAAGAATAGATCAGAATGATTTTGTTGACATGACTACAGACTGAAATAATGTGAATGAATTAACTGAATTTGCTC
TGTCAACTTTAGTAAATTGCCCATTGCCTTTGCTTTGTTCATAATTTCAGCAGGGCAGAATAAAAACCATGGGAGGCAAAGAAAGGAAAT
CCGGAAATATAGTCTTAACCTGGTGTTGTTCTAATTTTCCATCTGTTCTTCTGACTCAACTCACTGGCTATCGATGAATCAGTAGGTAGT
ATTTATAAGTCTTAGGAAAGACTACTCAAGTTAAGGTACTTCCCTATATCCATCTCTTTTAGGTACGCAAAGAGAACCAGTGGTGTGAAG
AGAAGTGAAATGTTGTGCCTGACACTGTAACACTGTAAGGATTGTTCCAAATACTAGTTGCACTGCTCTGTTTATAATTGTTAATATTAG
ACAAACAGTAGACAAATGCAGCAGCAAGTCAATTGTATTAGCAGAATATTGTCCTCATTGCATGTGTAGTTTGAGCACAGATCCCAAACC
TTACGGCCAAGTTTCTTCTAGTATGATGGAAAGTTTCTTTTTTCTTTGCTCTGAATAAAACTGAACTGTGGGTTCTCTATAAGTGGCATT
TTGGGCTTTCCCTCTTTTTTGTAAAGCAATGTCTGCCTAGTTTATTGTCCAGTTAACTTTAGTGACCTTTTAAAAGTTGGCATTGTAAAT

>63092_63092_4_PCBD2-SKP1_PCBD2_chr5_134246156_ENST00000254908_SKP1_chr5_133509713_ENST00000522552_length(amino acids)=257AA_BP=97
MGVVGSGAAVGGRQAARGAALGRRPMAAVLGALGATRRLLAALRGQSLGLAAMSSGTHRLTAEERNQAILDLKAAGWSELSERDAIYKEF
SFHNFNQMPSIKLQSSDGEIFEVDVEIAKQSVTIKTMLEDLGMDDEGDDDPVPLPNVNAAILKKVIQWCTHHKDDPPPPEDDENKEKRTD

--------------------------------------------------------------
>63092_63092_5_PCBD2-SKP1_PCBD2_chr5_134246156_ENST00000254908_SKP1_chr5_133509713_ENST00000522855_length(transcript)=1103nt_BP=450nt
AGAGTCCACCTGGCGGCCAAGGGCGCTGGCGACCGCTGAAGCTCCTGGGGGTGTTCGGGGTCCGGGCTGCGCCTGTGCCCGCGGGAAGGC
TGGGCGCTTCCCACACACAGACCCCGCTCCGGGCCAGCCCCGCAGGGAGACTACCAGGGCTGGCGGTAGCTGGGCGTGGTCGGGTCGGGG
GCGGCTGTGGGCGGCCGGCAGGCAGCGCGCGGGGCAGCCCTCGGCAGACGGCCAATGGCGGCGGTGCTCGGGGCGCTCGGGGCGACGCGG
CGCTTGTTGGCGGCGCTGCGAGGCCAGAGCCTAGGGCTAGCGGCCATGTCATCAGGTACTCACAGGTTGACTGCAGAGGAGAGGAACCAA
GCTATACTTGACCTTAAAGCAGCAGGATGGTCGGAATTAAGTGAGAGAGATGCCATCTACAAAGAATTCTCCTTCCACAATTTTAATCAG
ATGCCTTCAATTAAGTTGCAGAGTTCTGATGGAGAGATATTTGAAGTTGATGTGGAAATTGCCAAACAATCTGTGACTATTAAGACCATG
TTGGAAGATTTGGGAATGGATGATGAAGGAGATGATGACCCAGTTCCTCTACCAAATGTGAATGCAGCAATATTAAAAAAGGTCATTCAG
TGGTGCACCCACCACAAGGATGACCCTCCTCCTCCTGAAGATGATGAGAACAAAGAAAAGCGAACAGATGATATCCCTGTTTGGGACCAA
GAATTCCTGAAAGTTGACCAAGGAACACTTTTTGAACTCATTCTGGCTGCAAACTACTTAGACATCAAAGGTTTGCTTGATGTTACATGC
AAGACTGTTGCCAATATGATCAAGGGGAAAACTCCTGAGGAGATTCGCAAGACCTTCAATATCAAAAATGACTTTACTGAAGAGGAGGAA
GCCCAGGTACGCAAAGAGAACCAGTGGTGTGAAGAGAAGTGAAATGTTGTGCCTGACACTGTAACACTGTAAGGATTGTTCCAAATACTA
GTTGCACTGCTCTGTTTATAATTGTTAATATTAGACAAACAGTAGACAAATGCAGCAGCAAGTCAATTGTATTAGCAGAATATTGTCCTC

>63092_63092_5_PCBD2-SKP1_PCBD2_chr5_134246156_ENST00000254908_SKP1_chr5_133509713_ENST00000522855_length(amino acids)=260AA_BP=97
MGVVGSGAAVGGRQAARGAALGRRPMAAVLGALGATRRLLAALRGQSLGLAAMSSGTHRLTAEERNQAILDLKAAGWSELSERDAIYKEF
SFHNFNQMPSIKLQSSDGEIFEVDVEIAKQSVTIKTMLEDLGMDDEGDDDPVPLPNVNAAILKKVIQWCTHHKDDPPPPEDDENKEKRTD

--------------------------------------------------------------
>63092_63092_6_PCBD2-SKP1_PCBD2_chr5_134246156_ENST00000512783_SKP1_chr5_133509713_ENST00000353411_length(transcript)=9519nt_BP=236nt
CAGCCCTCGGCAGACGGCCAATGGCGGCGGTGCTCGGGGCGCTCGGGGCGACGCGGCGCTTGTTGGCGGCGCTGCGAGGCCAGAGCCTAG
GGCTAGCGGCCATGTCATCAGGTACTCACAGGTTGACTGCAGAGGAGAGGAACCAAGCTATACTTGACCTTAAAGCAGCAGGATGGTCGG
AATTAAGTGAGAGAGATGCCATCTACAAAGAATTCTCCTTCCACAATTTTAATCAGATGCCTTCAATTAAGTTGCAGAGTTCTGATGGAG
AGATATTTGAAGTTGATGTGGAAATTGCCAAACAATCTGTGACTATTAAGACCATGTTGGAAGATTTGGGAATGGATGATGAAGGAGATG
ATGACCCAGTTCCTCTACCAAATGTGAATGCAGCAATATTAAAAAAGGTCATTCAGTGGTGCACCCACCACAAGGATGACCCTCCTCCTC
CTGAAGATGATGAGAACAAAGAAAAGCGAACAGATGATATCCCTGTTTGGGACCAAGAATTCCTGAAAGTTGACCAAGGAACACTTTTTG
AACTCATTCTGGCTGCAAACTACTTAGACATCAAAGGTTTGCTTGATGTTACATGCAAGACTGTTGCCAATATGATCAAGGGGAAAACTC
CTGAGGAGATTCGCAAGACCTTCAATATCAAAAATGACTTTACTGAAGAGGAGGAAGCCCAGGTACGCAAAGAGAACCAGTGGTGTGAAG
AGAAGTGAAATGTTGTGCCTGACACTGTAACACTGTAAGGATTGTTCCAAATACTAGTTGCACTGCTCTGTTTATAATTGTTAATATTAG
ACAAACAGTAGACAAATGCAGCAGCAAGTCAATTGTATTAGCAGAATATTGTCCTCATTGCATGTGTAGTTTGAGCACAGATCCCAAACC
TTACGGCCAAGTTTCTTCTAGTATGATGGAAAGTTTCTTTTTTCTTTGCTCTGAATAAAACTGAACTGTGGGTTCTCTATAAGTGGCATT
TTGGGCTTTCCCTCTTTTTTGTAAAGCAATGTCTGCCTAGTTTATTGTCCAGTTAACTTTAGTGACCTTTTAAAAGTTGGCATTGTAAAT
AAAACAACTTGCAAAAAAGTTTTCTGGAATAGAATTAACAAAATATTATCTTTATTCATGAGTTGGAAACTGGAAAAAGGCTTCTTGAAG
TAAATGTTCTGAGTGGAGCTACTAGGATGTCTTCCAGCCTCCTGCAGTCAAGGAGTACCACTGTATTGATTAGCCTGTATGTAGCAGGGC
TCCCTTCATTGCATCTGAGGACTTGTTTTCTTTTTCTTTATTTTTAATCCTCTTAGTTTTAAATATATTGCCTAGAGACTCAGTTACTAC
CCAGTTTGTGGTTTTTTGGGAGAAATGTAACTGGACAGTTAGCTTTTCAATTAAAAAGACACTTAACCCATGTGGGATGTCATCTTTTTA
TAATTAGTGTTCCCATGTGGAGAAAATTATTCACACTACTTGCATGTAAAGAATAATTTAACTTTTAACATTAAAATATGTGGTAAAACC
CAGAAAGCATCCATCATGAATGCAAGATACTTTCAATAAAAAGTAAGTTATATAGTAGGTAGTTAAGTTTGCTTTTGTGGACTTAAATGT
GTCTCTTCACTTAAATGGGTTGAATGTGTATATATTTGTTCAGCTTGAAAAGACTTAGTTTATATCCTAGCTCACTGGAGGCTGCTGACA
TAACCATAACTTCTGTCCCTTCTAATTGTCATTTATATGCCTAACTGGAGCTAGTACTTTAATTCTTAACACAAAATTACTCTGCCATTG
TTTCCAGCTTCCCTCCTACAATAGAATGAAGTTTTTTTGATGGCTTGAGATGGCTCACAAATTTTGATTTTTTTTTCTTCCTTGTGCTCC
CTTTTTTTCTCCTTGCTTTTCCAGTTAACATCTATATTCACATGTAATCTTGTTTTCTCTTCACATTCACTGAGTTGTTCAGGCTCAGAT
CATCCCTTGACAGTAGTTTGCCTTCATCTCACCTTTCATTTGTCCCAAATTCACCTTATTTAATAAAGTCCCATATGTTGTCTCACTTAA
TTCCAATTTGTTGTCTGTACCAGAGATAGGAAACTATAATGTGTGGGTCAAATCAGGCCCATAGCCTGTTTTTGTAGTCTTTGAGCTAAA
AATGGTTTTTACGTTGTAAAGAGTTATTTAAAATTCTCTCTCTCTCTCTCTCTCTCTCTCAGGAGATAAGCTTGTTTTCTGTTTGTCCTG
GTTTTAGTGGGGAAGGTAGCGGTGTATAGTCCTAGCTGAATTGTCTCATCTACCAATTCCTGCTATTATAAGATCAACTTCTGCAAAAAC
CTTATCCACCTCAAGTATCCTTAGCAGCTGGGCATGGTGGCTTATGCCTGTAATCTCAACATTTTGGGAGGACAAGACAGGAGGATCGTT
TGAGCCCAGGAGTTCAAGACCAGCCTGGGCAACACAGAAAGTCCCTGTCTCTCCAAAAAAAAAAAAAAAAATTAGCAGTCATATGGTGCA
TGCCTATAATCCCAACTACTTGAGAGGCTGAGGTGGGAAGATGGCTTGAGCCTGAGAGGTCGAGGCTGCAGTGAGCTGGCATTGCACCAC
TGCACTCCAGTCTAGGCAATAGAGCGAGACCTTGTCTCAAAAACAAACCAGAAGTATCCTTAGCAGTATTATGACAAACAAATCTTCACT
GAAGGTCCAGGATTACTGCCATATGCCATGTTTAACTTGTAAAGGAAGTATCACCTTCTAAGAAACTGGAGCTTGTTATTACCACTTGAT
CTGTATAATACTCAGCAGTAGTTAGAATTATATGAGTAAATAACGTCACTATCCGTATTTAAAGGATAATGAGATCTTTCAGAAAGATTG
GATGGACAGACAATATAGTAGTAATTTAAATTTTTGTTTCCTGACTTTCTGTAGTCCCTAAACAAACAACAAAAAATCCTAGTAATCTTA
AACTTTTACATTAATAGAGATCCAAGAGAAAATAAGCCATTTTTCACCATTGTGGACCCAAATAAATCATAGACATGGTATTAAGAAGCC
CTTTTCAGTCTGGTTGCAGTATTATTTTCCTACCTTTCTTTTTCCTGTTCCCTGCTGTATGCCCACTATTCCTTTAATATATCTACTAGA
ACTTTTCTAGGCTTTCACCTGGAGTGAGTGGTCCTTTCTCATTATCACAGTAGCCAAACCTCAGTCTTCAAAACTCCACTCATTTCTGGC
TACTCTCTTACTTCCCAACTATTCTTCTAAACTAATATTGTGGCATTAAGTCATACCTTGAGGCTGGAGTTTTAGTGTCTTCATGGCCTT
GGGCAAGTTGGAAATAGGTACTACGGTTTTATAGATCTAGTGCAGTCTGCTTTATATTAGTTCCAGAACTTCATTGGAAGTCACTTGACA
GCAGGATTTAACTTGTATTTAGCAGCACTACTCCATGAATTTCAGTATAAGTAACAGAAGTGAAAAGTCCTTGTGAAATGCAGGTACAGG
GCATAATGAAAACAAGAAGAGTAGTTTTAATGCATGAGAGGGGAGAGCTTGATAATAGCTGATAATAGCCTTGGTTTGGAGAGTGGTTAC
TGATGAATTATGAAGACTTTCTCTAATTACTGTTATAGTAGTAAAGGAAAGAAAACCCTTGTTGATAAAGTAAACTTAGGGATTAATTAG
GAAATGCCTTTTATTTCACCAGGAAAGAGAATGAGAGGAAGAAGGTATTTGGCAGATTTGGGTGATTGAAGGATGTTTGTCGGTTTCCTC
TGTAAACAACATGCTGCTTTCTGCAGTGTGCTGCTTTTAATGATGAAGTCCTTTCAAGGACTCCATGGCAGTCCTTTGGCTTCTCACCTT
TTCATTGATTATGTCACTTGTGATCTAAAAGTAAACCAAAACCTTCCTGAATGTTAGCTTATTATTTTCTCCTTAACATTGTCATAGGCT
AAAGATGTGCCCCCTCAAATTCTAATAATTTTTTTTTTTTTTTTTTTTTTTTTGAGACAGAGTCTCACTCTGTCGCCCAGACTGGAATGC
AGTGGTGCGATCTCAGCTCACTGCAACCTCCGCCTCCTGGGTTCAAGTGATTCTCCTGCCTCAGCCTCCCGAGTAGCTGGGATTACAGGC
ACATGCCACCATGCCTGGCTAATTTTTTTGTGTTTTTATTAGAGATGGAGTTTTACCATATTGGCCAGGCTGGTCTTGAACTCCTGACCT
TGTGATCCGCCCGCCTTAGCCTCCGAAAGTGCTGAGGTTACACGTGTGACCCACCGCACACGGCCCTAATAATTCTTAAGTTGTAGAAGC
AAGTTACTCTTTTGAAGTGCCATGTGTTAGCTTGCCTTAATCTATTCTTGGTATACAAAATAGATACTGCTTTACAGTTCTTATATTTTC
TCAGAGATTCACAAAATCATCCTGTAGCTCCCTGTGTGGGATTATAGCTGTGACTTTTTACTCTACAACTGTCAGAATACACCAGCTCCT
GGAATTAAGCAAGAACTATATTGTGACTTGGTTGGACAGGTAACTGCAGCCTTGTAACATGACATCATAGTAATGCTGAGCTTATCTTAA
AACTAGCTGGGGAGGGAGGATAGTAACAGTGAGTCACTGTGGGCATCTCACTTAGGGCAGGCAGATATTCCAAATCACATTGATTTTTCA
GTTTACGTAAAAATTGACCAATCCTATGGGCTGTGTTCTGATCCCAACATAAATTTTGTTTAAGTTAATTTGCCTAGGCTCTCAATAAGG
CAGTTTGGGAATATAAGGTGATTTTCCACCAGAAAAGAGAAAATTGAGAGAGCAGCAGACCTCTTGCTCTCAGCACCCTTTACAAGCTTA
ACTTTTGCTTGCCACCATTAGCTTTTGAAGATTTTTTTTAACTGCTCCTTGCAGAGCAGGACTACCCCATAGGCAGTGTGCCCAGAGTAG
CCCGAAGAGCTTTTTGATTCTTCTTTTAAGAGACAAGGTCTCACCTCTGCCCCCCAGGCTGGAGTGCAGTGATGTGATCACAGCTCATTG
CAGCCTCGAACTCTTGGGCTCCAACAGTCCTCCTGCCTCAGCCTCCTGAATAGCTAGGACTACATGTGTGTGCTACCATGCCTTGCTAGT
TTTTGTTTTTTTAAATTGATTTTTATAGAGATGAGGTCTCCTCATGTTGCCCAGGCTGTTTTCGAATTCCTGGGCTCAAGATCCTCCTGC
CTCAACCTCCCAAAGTGCTGGTATTACAGATGTGAGCCACAGCACCCACCAATTTTTCCTTTTCTAAAGCTCAGTGTACATTCTGGTAGG
AAGGAATCAACCAAGTAAATGTTCTCCCTACAAAGTTGTTTGAGGATTTGAAAAGTTAATCTTCAATTATCTGGATTTGAAACCAGTCTA
TAACTTTTTAAGCTAGGAAGAAGTCAAGAATAAGAAGATTGCAAGCAAAGGGAAAGCTTACAAAATGGCTGAATCCTTAAAGTGTAGCTC
CTGGCTTCTCCTTGGTAGGAAGCATTAGACATGGTTTCCCTCTAGGGAGCTGGGAGCTTTTGGTGTAGTTCAGGAGAGAAGGCATAAATA
CTGCTGGGAGGGAGTGGATAACTCTAATAAAAATGTTCCTGGGCTGGGCACGGTGGCTCACGCCTGTAATCCCAACATTTTCAGAGGCTG
AGGTGTGCAGATCACGAGGTCAAGAGATCGAGACCATCCTGGCCAACATGGTGAAACCTCATCTCTACTAAAAATACAAAAATTAGCTGG
GCGTGGTGGCACATGCCTGTAGTCCCAGCAACTCGGGAGGCTGAGGCAGGAGAACCGCTTGAACCCGGGAGGCGGAAGTTGCAGTGAGCC
GACATCACGCCACTGACTGCAGTCCAGCCTGGCGACAGAGCGAGACTCCGTTTCAAAAAAAAAAAGTTTCTGGACAGAACAGATTAATGA
GCCAATGGGGGGCTACAGAGCTGAAAGGTGCTACGAAAGGTTTTGTAAAGTGAAACTAATTTGGTTTCAAGAATCAAGTTGGATTTGTTT
GGGGGTGGACAGATGCCAAAGTGAGGAAAAAGCAGTGCACAGTCAGGAACTAACAGCAGAAGGTTGGGTGTTGGTACATTTCCCTGAGAA
TATAGACTAAAGAGAAATTAGGGCAGGATTAGTCACAGTACTTTGCTGACACTCAGTAGTATTTTATCAGCATTTATTCATCAGACCCAC
ATTAGGCAGGGCAATTTTTGAGTGAGCTAAATTCTAATTTTTTTAATTTTAATTTTTATTTATTTATTTTTTGGCTGTTCAACTAAACCA
GTCTTTTGAATGTTGGGGGTTTTACAGTTAGAGTCCTGATGACTTTTTCTTGTTTACTGTTGTTAAAAATCACTACCTCCAGTGGTCACA
GAGAATGAGTAAGAGAACTGGCTGTGCATATCAAGATGAAGTATGGTGTAAGAAATATTTCAGAGCATGTCCTTTGGCCCAAGATTGAGC
CATTTGGACACCTAAGCAGGATTGGCTGAATGTTATCCTTTCTGCTGAGGCATCAGTGGAGATGATCATTAGTGGTGGCCGAAAAGTGTT
GTCGAAGGTGCTCTTGCTTGACACACTTCCAATGCGGGACATAGTTTGAGTGATAGATGGCTAATTCATTGATAATGTACTTGTTGCCTT
GCAGTCTTGTGTACTGCTGGCTACCTCTGGTCTGTGTGCCAGTATTGAGCAGCATTCTATGGGAGGAATGTAGTTGCTCATAACAGTGTC
TGCTTCCACATCTGTAGTTCTTGCGACCTTCTGATATCTGTCAACTTTAAATTTTCTGGAAGTATTTAAGTATATTCAGACCTTCTGATA
TCTCTTAACTTCAAATTTTCAACCTGCTATATAGCAGCCTCTTATTGCACACTGAGGATCAGCTTATTTCCTTAAAGTGCTCTCACTTTG
AATACCTCCCACCTATCTGGTGAAAATTCTTATTTGTCCTTTCTTTCCTGAATGTACCATTTCACAACCTCTAACTGCCTTCTTCAGTTG
CTTTGCAGATTTTTCTGTTCCAGGAAGCTTACGGAAAGGGGTGGGAAAATAGAGAAGCTGTACTCTATCCTCAAGTACTCAAGCAGGGTT
TCCAGAGTGGCTTTGTAAAAATTTTTATTTATTTATTTATTTATTTTTGGTGAGTGGAACCTGGCTTTTCCTCTTCCCTCCCCAAGCCCC
ACCCCGCTTCCTGACATTGCACATGCCTGAAAGAACTAGGCTTCAGATAAAAGAATGAGAACACTTGAATGAAAAAGGAAGACTTGGTCC
AGAGCCCCTGGTGAATATGAAAGAAGTATTGGCCTGGACTATCTCCCGCATAATTCACAGCTGCTATCTTGTCTTCAGAAGTGAAACATC
CCTTACCAATAGTGACCTAACTTGTGAGGACTGCTTGTGATAGTATAGTTCCCACCCCCAGGACATAAGTTTTCCCTTTCCAGTTAACAT
GCCTAATCCCATGCTATCTTTAAGAGCTTGAAAATCCTTCCTGACCTGAGCTAGGCTTTTATTCTAAGGGACTGTGTATGTGAACATCCC
CACCATCTATGTTTCCTGTTTTCAAACTCGGTGCCGTTTTGAGTATTTTCAGATGCTCACTGCCAGTAATGGTTTGTTAGTAGCTCCAAA
CTATTAGAGAAGAGCTCAGGAGTCAGAATTTGAAAGATGCCCATAGGGTGATTTGAGATTTGGAACAAGGTTATCACAATAAGTTGGGAT
TGGGGGAGTTGACACAACCAGGGTCTGCTTGGGTGGGCAGCTGTTTCAGAAACCCTTGGTGAACTCTTAAAGCCCTGAAGAGCTTAAAAA
ATGCTCTGAAGAGATCTGAGAGTCGCAGTTAAGGACTCTCAAAGAACCTCAAAGAAAAGCCAACTTAGCCTTTTTATACAATTAACTAGA
TTTGGGTCTTAAATTCTACTTTGACATATAGGCCTAAGAGGTAGTTTAACATGGCCTTGTTACCCTTACCCCTTCTGTTCTGTGCTGTTT
TCTGAGAAACGGATGCAGGAACTGATTCCCTTTCTTCCTCTCTGGAACAGGATATAAAGAACCCTTCCGCTTCCCTTTACTTGTGGCCTT
CCTGGCCAGGCTTATGTATACTGAACAAAGCTAGGGTGCAGTGCTTCTGAGCTAGCTGTTAGGGGTCCACAGCCAGAAGGAATGGGAGAC
CACAGGAGCCATTCAAAAGATAATTACATGTCAGAAGAGAGTCCATCCATGGGGTTCTGTTAAAGTAGACACCTTCACGTTGGGAGACAT
AGGCTTTGTCTGCTTGCTGGGCTGAACCCTCACCATATCCACAGAGAACAAAATGGGGAGCAGCTGTACCAGGGGAGGGATGAACGTCTT
TCACCCAAGTTGCCAGTCTGCTAGTTGTCTGGAAATGTTCAAGGGAGGCTAAGGTATCTTGTCTTATGATGTCTCAGGAAACAGGGTTGG
TTCTCAGCTGGCAGTGAAGGGGGACTGGTGTGGTATTAGCAGTTGAACTTGAGGTTGCAATCTCAAGTCACCCTCTGGCCTCGCAGGAAT
GCACCAGGGTGATTTGGGAGGATCTGAGTTTCCTTTATGAAGTCAGATTAAAAAAAAAAAAAGCTGATCTGATTTAAACAGAGTTGCCAA
AGACTTCCCCGCCAATACACAAAGACTGCATTGTTCAGGTACCCTGTGTACTCTAAGTGAGACACCAAATCAGATGCAGCAACCTGGTCT
TGCATAAGCCCTGGTTAGAATGTAGGTTTTTTAAACAACTAGGCCAGTAGCCAGAACAGAATTCTTTAAAATGGGACAGATGTCCAGAGA
ATGGCTAGTGTCCTCTAGCACTCTCTCAGAAGCAAAAGCAAGTCTGGGGTTACAACTTCCAGTGGCCTACTTTAAATAGACGCTGTTCTG
GAAAATGACTTTATACTTTAAACACAAAATCCAAAAAATAGAACTCAGTGGAGTGACAATGACAATGCATGATGGTGGCCCAGTGGCTGT
CCCATGTGAAATACTTCTTGCCTGACATGTATCATCTACTTGTTGACTGACCTATTGAGGTGCCTTCATGACACCTTTTACATTCATGAT
AGGTCTCAGGAAGACAGCAGTGTACTTGGTGGAAACTCATGTAAAAAGTGGGTTGTAGGGAGCTAAACAGTGAGTACACATGGTATATGG
ATACGGAATGGAATAATAGACATTGGAGACTTCAAAAGGTGGGAGATGAAAGGGGGATGAGGTATGAAATCCTACCTGTTGAGTACAATG
TACACTACTTACGTGCACAGTACACTGTTTGGGTGAGAGGCACACTAAAAGCCCGGACCTCACCGCTACCCAGTATGTTCATGTAACACA
GCTGCACTTGTACCCCCTAAATGTATACAAATAATCTAAAAATAGCCCGGACCTCACCGCTACACAATATATTCATGTAACACAGCTGCA

>63092_63092_6_PCBD2-SKP1_PCBD2_chr5_134246156_ENST00000512783_SKP1_chr5_133509713_ENST00000353411_length(amino acids)=235AA_BP=72
MAAVLGALGATRRLLAALRGQSLGLAAMSSGTHRLTAEERNQAILDLKAAGWSELSERDAIYKEFSFHNFNQMPSIKLQSSDGEIFEVDV
EIAKQSVTIKTMLEDLGMDDEGDDDPVPLPNVNAAILKKVIQWCTHHKDDPPPPEDDENKEKRTDDIPVWDQEFLKVDQGTLFELILAAN

--------------------------------------------------------------
>63092_63092_7_PCBD2-SKP1_PCBD2_chr5_134246156_ENST00000512783_SKP1_chr5_133509713_ENST00000517625_length(transcript)=953nt_BP=236nt
CAGCCCTCGGCAGACGGCCAATGGCGGCGGTGCTCGGGGCGCTCGGGGCGACGCGGCGCTTGTTGGCGGCGCTGCGAGGCCAGAGCCTAG
GGCTAGCGGCCATGTCATCAGGTACTCACAGGTTGACTGCAGAGGAGAGGAACCAAGCTATACTTGACCTTAAAGCAGCAGGATGGTCGG
AATTAAGTGAGAGAGATGCCATCTACAAAGAATTCTCCTTCCACAATTTTAATCAGATGCCTTCAATTAAGTTGCAGAGTTCTGATGGAG
AGATATTTGAAGTTGATGTGGAAATTGCCAAACAATCTGTGACTATTAAGACCATGTTGGAAGATTTGGGAATGGATGATGAAGGAGATG
ATGACCCAGTTCCTCTACCAAATGTGAATGCAGCAATATTAAAAAAGGTCATTCAGTGGTGCACCCACCACAAGGATGACCCTCCTCCTC
CTGAAGATGATGAGAACAAAGAAAAGCGAACAGATGATATCCCTGTTTGGGACCAAGAATTCCTGAAAGTTGACCAAGGAACACTTTTTG
AACTCATTCTGGCTGCAAACTACTTAGACATCAAAGGTTTGCTTGATGTTACATGCAAGACTGTTGCCAATATGATCAAGGGGAAAACTC
CTGAGGAGATTCGCAAGACCTTCAATATCAAAAATGACTTTACTGAAGAGGAGGAAGCCCAGGTACGCAAAGAGAACCAGTGGTGTGAAG
AGAAGTGAAATGTTGTGCCTGACACTGTAACACTGTAAGGATTGTTCCAAATACTAGTTGCACTGCTCTGTTTATAATTGTTAATATTAG
ACAAACAGTAGACAAATGCAGCAGCAAGTCAATTGTATTAGCAGAATATTGTCCTCATTGCATGTGTAGTTTGAGCACAGATCCCAAACC

>63092_63092_7_PCBD2-SKP1_PCBD2_chr5_134246156_ENST00000512783_SKP1_chr5_133509713_ENST00000517625_length(amino acids)=235AA_BP=72
MAAVLGALGATRRLLAALRGQSLGLAAMSSGTHRLTAEERNQAILDLKAAGWSELSERDAIYKEFSFHNFNQMPSIKLQSSDGEIFEVDV
EIAKQSVTIKTMLEDLGMDDEGDDDPVPLPNVNAAILKKVIQWCTHHKDDPPPPEDDENKEKRTDDIPVWDQEFLKVDQGTLFELILAAN

--------------------------------------------------------------
>63092_63092_8_PCBD2-SKP1_PCBD2_chr5_134246156_ENST00000512783_SKP1_chr5_133509713_ENST00000521216_length(transcript)=1069nt_BP=236nt
CAGCCCTCGGCAGACGGCCAATGGCGGCGGTGCTCGGGGCGCTCGGGGCGACGCGGCGCTTGTTGGCGGCGCTGCGAGGCCAGAGCCTAG
GGCTAGCGGCCATGTCATCAGGTACTCACAGGTTGACTGCAGAGGAGAGGAACCAAGCTATACTTGACCTTAAAGCAGCAGGATGGTCGG
AATTAAGTGAGAGAGATGCCATCTACAAAGAATTCTCCTTCCACAATTTTAATCAGATGCCTTCAATTAAGTTGCAGAGTTCTGATGGAG
AGATATTTGAAGTTGATGTGGAAATTGCCAAACAATCTGTGACTATTAAGACCATGTTGGAAGATTTGGGAATGGATGATGAAGGAGATG
ATGACCCAGTTCCTCTACCAAATGTGAATGCAGCAATATTAAAAAAGGTCATTCAGTGGTGCACCCACCACAAGGATGACCCTCCTCCTC
CTGAAGATGATGAGAACAAAGAAAAGCGAACAGATGATATCCCTGTTTGGGACCAAGAATTCCTGAAATATACTTTAAGGAAAACAACTG
TCTCTTTACAGGCTGCAAACTACTTAGACATCAAAGGTTTGCTTGATGTTACATGCAAGACTGTTGCCAATATGATCAAGGGGAAAACTC
CTGAGGAGATTCGCAAGACCTTCAATATCAAAAATGACTTTACTGAAGAGGAGGAAGCCCAGGTACGCAAAGAGAACCAGTGGTGTGAAG
AGAAGTGAAATGTTGTGCCTGACACTGTAACACTGTAAGGATTGTTCCAAATACTAGTTGCACTGCTCTGTTTATAATTGTTAATATTAG
ACAAACAGTAGACAAATGCAGCAGCAAGTCAATTGTATTAGCAGAATATTGTCCTCATTGCATGTGTAGTTTGAGCACAGATCCCAAACC
TTACGGCCAAGTTTCTTCTAGTATGATGGAAAGTTTCTTTTTTCTTTGCTCTGAATAAAACTGAACTGTGGGTTCTCTATAAGTGGCATT

>63092_63092_8_PCBD2-SKP1_PCBD2_chr5_134246156_ENST00000512783_SKP1_chr5_133509713_ENST00000521216_length(amino acids)=235AA_BP=72
MAAVLGALGATRRLLAALRGQSLGLAAMSSGTHRLTAEERNQAILDLKAAGWSELSERDAIYKEFSFHNFNQMPSIKLQSSDGEIFEVDV
EIAKQSVTIKTMLEDLGMDDEGDDDPVPLPNVNAAILKKVIQWCTHHKDDPPPPEDDENKEKRTDDIPVWDQEFLKYTLRKTTVSLQAAN

--------------------------------------------------------------
>63092_63092_9_PCBD2-SKP1_PCBD2_chr5_134246156_ENST00000512783_SKP1_chr5_133509713_ENST00000522552_length(transcript)=1809nt_BP=236nt
CAGCCCTCGGCAGACGGCCAATGGCGGCGGTGCTCGGGGCGCTCGGGGCGACGCGGCGCTTGTTGGCGGCGCTGCGAGGCCAGAGCCTAG
GGCTAGCGGCCATGTCATCAGGTACTCACAGGTTGACTGCAGAGGAGAGGAACCAAGCTATACTTGACCTTAAAGCAGCAGGATGGTCGG
AATTAAGTGAGAGAGATGCCATCTACAAAGAATTCTCCTTCCACAATTTTAATCAGATGCCTTCAATTAAGTTGCAGAGTTCTGATGGAG
AGATATTTGAAGTTGATGTGGAAATTGCCAAACAATCTGTGACTATTAAGACCATGTTGGAAGATTTGGGAATGGATGATGAAGGAGATG
ATGACCCAGTTCCTCTACCAAATGTGAATGCAGCAATATTAAAAAAGGTCATTCAGTGGTGCACCCACCACAAGGATGACCCTCCTCCTC
CTGAAGATGATGAGAACAAAGAAAAGCGAACAGATGATATCCCTGTTTGGGACCAAGAATTCCTGAAAGTTGACCAAGGAACACTTTTTG
AACTCATTCTGGCTGCAAACTACTTAGACATCAAAGGTTTGCTTGATGTTACATGCAAGACTGTTGCCAATATGATCAAGGGGAAAACTC
CTGAGGAGATTCGCAAGACCTTCAATATCAAAAATGACTTTACTGAAGAGGAGGAAGCCCAGGTAGGTAGCACACAGTTTTGTCTTTGAT
CACATGCTCTTAAAAAGGGAGTAACACCTATAACATGCCAGCAAAAGAGGTGACTGTATCAAGTAGTCTTGATACTTTAGGGATAATATG
TACTTAATGTGTCTTAAACATACTCTTACTGTTCTGTCTTTATGAATCTGAACACTTAGATGATACTGCATTTTAAGCATAAGAACAATT
AGTTTTCAATGAGAAGAGCTCTTGTTAATGTATTAACAGTTACTAGTTTTGGCACCTGCAACTTTCTGTATAGACCATACATATCTGACA
TCAGAAAAGCAGGCCCTAGAGAGAAGTATATACTAGGGTACTTTAGAGCAACTTAATGAGGGGAGGAAATGAAAGAATAGATCAGAATGA
TTTTGTTGACATGACTACAGACTGAAATAATGTGAATGAATTAACTGAATTTGCTCTGTCAACTTTAGTAAATTGCCCATTGCCTTTGCT
TTGTTCATAATTTCAGCAGGGCAGAATAAAAACCATGGGAGGCAAAGAAAGGAAATCCGGAAATATAGTCTTAACCTGGTGTTGTTCTAA
TTTTCCATCTGTTCTTCTGACTCAACTCACTGGCTATCGATGAATCAGTAGGTAGTATTTATAAGTCTTAGGAAAGACTACTCAAGTTAA
GGTACTTCCCTATATCCATCTCTTTTAGGTACGCAAAGAGAACCAGTGGTGTGAAGAGAAGTGAAATGTTGTGCCTGACACTGTAACACT
GTAAGGATTGTTCCAAATACTAGTTGCACTGCTCTGTTTATAATTGTTAATATTAGACAAACAGTAGACAAATGCAGCAGCAAGTCAATT
GTATTAGCAGAATATTGTCCTCATTGCATGTGTAGTTTGAGCACAGATCCCAAACCTTACGGCCAAGTTTCTTCTAGTATGATGGAAAGT
TTCTTTTTTCTTTGCTCTGAATAAAACTGAACTGTGGGTTCTCTATAAGTGGCATTTTGGGCTTTCCCTCTTTTTTGTAAAGCAATGTCT
GCCTAGTTTATTGTCCAGTTAACTTTAGTGACCTTTTAAAAGTTGGCATTGTAAATAAAACAACTTGCAAAAAAGTTTTCTGGAATAGAA

>63092_63092_9_PCBD2-SKP1_PCBD2_chr5_134246156_ENST00000512783_SKP1_chr5_133509713_ENST00000522552_length(amino acids)=232AA_BP=72
MAAVLGALGATRRLLAALRGQSLGLAAMSSGTHRLTAEERNQAILDLKAAGWSELSERDAIYKEFSFHNFNQMPSIKLQSSDGEIFEVDV
EIAKQSVTIKTMLEDLGMDDEGDDDPVPLPNVNAAILKKVIQWCTHHKDDPPPPEDDENKEKRTDDIPVWDQEFLKVDQGTLFELILAAN

--------------------------------------------------------------
>63092_63092_10_PCBD2-SKP1_PCBD2_chr5_134246156_ENST00000512783_SKP1_chr5_133509713_ENST00000522855_length(transcript)=889nt_BP=236nt
CAGCCCTCGGCAGACGGCCAATGGCGGCGGTGCTCGGGGCGCTCGGGGCGACGCGGCGCTTGTTGGCGGCGCTGCGAGGCCAGAGCCTAG
GGCTAGCGGCCATGTCATCAGGTACTCACAGGTTGACTGCAGAGGAGAGGAACCAAGCTATACTTGACCTTAAAGCAGCAGGATGGTCGG
AATTAAGTGAGAGAGATGCCATCTACAAAGAATTCTCCTTCCACAATTTTAATCAGATGCCTTCAATTAAGTTGCAGAGTTCTGATGGAG
AGATATTTGAAGTTGATGTGGAAATTGCCAAACAATCTGTGACTATTAAGACCATGTTGGAAGATTTGGGAATGGATGATGAAGGAGATG
ATGACCCAGTTCCTCTACCAAATGTGAATGCAGCAATATTAAAAAAGGTCATTCAGTGGTGCACCCACCACAAGGATGACCCTCCTCCTC
CTGAAGATGATGAGAACAAAGAAAAGCGAACAGATGATATCCCTGTTTGGGACCAAGAATTCCTGAAAGTTGACCAAGGAACACTTTTTG
AACTCATTCTGGCTGCAAACTACTTAGACATCAAAGGTTTGCTTGATGTTACATGCAAGACTGTTGCCAATATGATCAAGGGGAAAACTC
CTGAGGAGATTCGCAAGACCTTCAATATCAAAAATGACTTTACTGAAGAGGAGGAAGCCCAGGTACGCAAAGAGAACCAGTGGTGTGAAG
AGAAGTGAAATGTTGTGCCTGACACTGTAACACTGTAAGGATTGTTCCAAATACTAGTTGCACTGCTCTGTTTATAATTGTTAATATTAG

>63092_63092_10_PCBD2-SKP1_PCBD2_chr5_134246156_ENST00000512783_SKP1_chr5_133509713_ENST00000522855_length(amino acids)=235AA_BP=72
MAAVLGALGATRRLLAALRGQSLGLAAMSSGTHRLTAEERNQAILDLKAAGWSELSERDAIYKEFSFHNFNQMPSIKLQSSDGEIFEVDV
EIAKQSVTIKTMLEDLGMDDEGDDDPVPLPNVNAAILKKVIQWCTHHKDDPPPPEDDENKEKRTDDIPVWDQEFLKVDQGTLFELILAAN

--------------------------------------------------------------

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Fusion Gene PPI Analysis for PCBD2-SKP1


check button Go to ChiPPI (Chimeric Protein-Protein interactions) to see the chimeric PPI interaction in

ChiPPI page.


check button Protein-protein interactors with each fusion partner protein in wild-type (BIOGRID-3.4.160)
HgeneHgene's interactorsTgeneTgene's interactors


check button - Retained PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenStill interaction with
TgeneSKP1chr5:134246156chr5:133509713ENST0000035341106104_1630.0164.0the F-box domain of F-box proteins
TgeneSKP1chr5:134246156chr5:133509713ENST0000051762517104_1630.0164.0the F-box domain of F-box proteins
TgeneSKP1chr5:134246156chr5:133509713ENST0000052255205104_1630.0161.0the F-box domain of F-box proteins
TgeneSKP1chr5:134246156chr5:133509713ENST0000052285517104_1630.0164.0the F-box domain of F-box proteins


check button - Lost PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


check button - Retained PPIs, but lost function due to frame-shift fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


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Related Drugs for PCBD2-SKP1


check button Drugs targeting genes involved in this fusion gene.
(DrugBank Version 5.1.8 2021-05-08)
PartnerGeneUniProtAccDrugBank IDDrug nameDrug activityDrug typeDrug status

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Related Diseases for PCBD2-SKP1


check button Diseases associated with fusion partners.
(DisGeNet 4.0)
PartnerGeneDisease IDDisease name# pubmedsSource