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Center for Computational Systems Medicine
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Fusion Gene Summary

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Fusion Gene ORF analysis

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Fusion Genomic Features

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Fusion Protein Features

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Fusion Gene Sequence

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Fusion Gene PPI analysis

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Related Drugs

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Related Diseases

Fusion gene:PCM1-RET (FusionGDB2 ID:63341)

Fusion Gene Summary for PCM1-RET

check button Fusion gene summary
Fusion gene informationFusion gene name: PCM1-RET
Fusion gene ID: 63341
HgeneTgene
Gene symbol

PCM1

RET

Gene ID

5108

5979

Gene namepericentriolar material 1ret proto-oncogene
SynonymsPTC4|RET/PCM-1CDHF12|CDHR16|HSCR1|MEN2A|MEN2B|MTC1|PTC|RET-ELE1
Cytomap

8p22

10q11.21

Type of geneprotein-codingprotein-coding
Descriptionpericentriolar material 1 proteinPCM-1hPCM-1pericentriolar material 1, PCM1proto-oncogene tyrosine-protein kinase receptor RetRET receptor tyrosine kinasecadherin family member 12cadherin-related family member 16proto-oncogene c-Retrearranged during transfectionret proto-oncogene (multiple endocrine neoplasia and medullary
Modification date2020032720200322
UniProtAcc.

RTL1

Ensembl transtripts involved in fusion geneENST00000325083, ENST00000327578, 
ENST00000519253, ENST00000524226, 
ENST00000518537, ENST00000518936, 
ENST00000340058, ENST00000355710, 
Fusion gene scores* DoF score16 X 16 X 12=307232 X 31 X 11=10912
# samples 1648
** MAII scorelog2(16/3072*10)=-4.26303440583379
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0		log2(48/10912*10)=-4.50673733341565
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0
Context

PubMed: PCM1 [Title/Abstract] AND RET [Title/Abstract] AND fusion [Title/Abstract]

Most frequent breakpointPCM1(17851129)-RET(43612030), # samples:2
Anticipated loss of major functional domain due to fusion event.PCM1-RET seems lost the major protein functional domain in Hgene partner, which is a CGC due to the frame-shifted ORF.
PCM1-RET seems lost the major protein functional domain in Hgene partner, which is a essential gene due to the frame-shifted ORF.
PCM1-RET seems lost the major protein functional domain in Tgene partner, which is a CGC due to the frame-shifted ORF.
PCM1-RET seems lost the major protein functional domain in Tgene partner, which is a IUPHAR drug target due to the frame-shifted ORF.
PCM1-RET seems lost the major protein functional domain in Tgene partner, which is a kinase due to the frame-shifted ORF.
* DoF score (Degree of Frequency) = # partners X # break points X # cancer types
** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10)

check button Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez
PartnerGeneGO IDGO termPubMed ID
TgeneRET

GO:0030155

regulation of cell adhesion

21357690

TgeneRET

GO:0030335

positive regulation of cell migration

20702524

TgeneRET

GO:0033619

membrane protein proteolysis

21357690

TgeneRET

GO:0033630

positive regulation of cell adhesion mediated by integrin

20702524

TgeneRET

GO:0035860

glial cell-derived neurotrophic factor receptor signaling pathway

28953886

TgeneRET

GO:0043410

positive regulation of MAPK cascade

28846099


check buttonFusion gene breakpoints across PCM1 (5'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.
all structure

check buttonFusion gene breakpoints across RET (3'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.
all structure

check button Fusion gene information from two resources (ChiTars 5.0 and ChimerDB 4.0)
* All genome coordinats were lifted-over on hg19.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
SourceDiseaseSampleHgeneHchrHbpHstrandTgeneTchrTbpTstrand
ChimerDB4adenocarcinomaAJ297349PCM1chr8

17851129

RETchr10

43612030
ChimerKB3..PCM1chr8

17851128

+RETchr10

43612031

+
ChimerKB3..PCM1chr8

17851129

+RETchr10

43612030

+
ChimerKB3..PCM1chr8

17867253

+RETchr10

43619118

+
ChiTaRS5.0N/AAJ297349PCM1chr8

17851129

+RETchr10

43612030

+


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Fusion Gene ORF analysis for PCM1-RET

check button Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
ORFHenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrand
Frame-shiftENST00000325083ENST00000340058PCM1chr8

17867253

+RETchr10

43619118

+
Frame-shiftENST00000325083ENST00000355710PCM1chr8

17867253

+RETchr10

43619118

+
Frame-shiftENST00000327578ENST00000340058PCM1chr8

17867253

+RETchr10

43619118

+
Frame-shiftENST00000327578ENST00000355710PCM1chr8

17867253

+RETchr10

43619118

+
Frame-shiftENST00000519253ENST00000340058PCM1chr8

17867253

+RETchr10

43619118

+
Frame-shiftENST00000519253ENST00000355710PCM1chr8

17867253

+RETchr10

43619118

+
Frame-shiftENST00000524226ENST00000340058PCM1chr8

17867253

+RETchr10

43619118

+
Frame-shiftENST00000524226ENST00000355710PCM1chr8

17867253

+RETchr10

43619118

+
In-frameENST00000325083ENST00000340058PCM1chr8

17851129

RETchr10

43612030

In-frameENST00000325083ENST00000340058PCM1chr8

17851128

+RETchr10

43612031

+
In-frameENST00000325083ENST00000340058PCM1chr8

17851129

+RETchr10

43612030

+
In-frameENST00000325083ENST00000355710PCM1chr8

17851129

RETchr10

43612030

In-frameENST00000325083ENST00000355710PCM1chr8

17851128

+RETchr10

43612031

+
In-frameENST00000325083ENST00000355710PCM1chr8

17851129

+RETchr10

43612030

+
In-frameENST00000327578ENST00000340058PCM1chr8

17851129

RETchr10

43612030

In-frameENST00000327578ENST00000340058PCM1chr8

17851128

+RETchr10

43612031

+
In-frameENST00000327578ENST00000340058PCM1chr8

17851129

+RETchr10

43612030

+
In-frameENST00000327578ENST00000355710PCM1chr8

17851129

RETchr10

43612030

In-frameENST00000327578ENST00000355710PCM1chr8

17851128

+RETchr10

43612031

+
In-frameENST00000327578ENST00000355710PCM1chr8

17851129

+RETchr10

43612030

+
In-frameENST00000519253ENST00000340058PCM1chr8

17851129

RETchr10

43612030

In-frameENST00000519253ENST00000340058PCM1chr8

17851128

+RETchr10

43612031

+
In-frameENST00000519253ENST00000340058PCM1chr8

17851129

+RETchr10

43612030

+
In-frameENST00000519253ENST00000355710PCM1chr8

17851129

RETchr10

43612030

In-frameENST00000519253ENST00000355710PCM1chr8

17851128

+RETchr10

43612031

+
In-frameENST00000519253ENST00000355710PCM1chr8

17851129

+RETchr10

43612030

+
In-frameENST00000524226ENST00000340058PCM1chr8

17851129

RETchr10

43612030

In-frameENST00000524226ENST00000340058PCM1chr8

17851128

+RETchr10

43612031

+
In-frameENST00000524226ENST00000340058PCM1chr8

17851129

+RETchr10

43612030

+
In-frameENST00000524226ENST00000355710PCM1chr8

17851129

RETchr10

43612030

In-frameENST00000524226ENST00000355710PCM1chr8

17851128

+RETchr10

43612031

+
In-frameENST00000524226ENST00000355710PCM1chr8

17851129

+RETchr10

43612030

+
intron-3CDSENST00000518537ENST00000340058PCM1chr8

17851129

RETchr10

43612030

intron-3CDSENST00000518537ENST00000340058PCM1chr8

17851128

+RETchr10

43612031

+
intron-3CDSENST00000518537ENST00000340058PCM1chr8

17851129

+RETchr10

43612030

+
intron-3CDSENST00000518537ENST00000340058PCM1chr8

17867253

+RETchr10

43619118

+
intron-3CDSENST00000518537ENST00000355710PCM1chr8

17851129

RETchr10

43612030

intron-3CDSENST00000518537ENST00000355710PCM1chr8

17851128

+RETchr10

43612031

+
intron-3CDSENST00000518537ENST00000355710PCM1chr8

17851129

+RETchr10

43612030

+
intron-3CDSENST00000518537ENST00000355710PCM1chr8

17867253

+RETchr10

43619118

+
intron-3CDSENST00000518936ENST00000340058PCM1chr8

17851129

RETchr10

43612030

intron-3CDSENST00000518936ENST00000340058PCM1chr8

17851128

+RETchr10

43612031

+
intron-3CDSENST00000518936ENST00000340058PCM1chr8

17851129

+RETchr10

43612030

+
intron-3CDSENST00000518936ENST00000340058PCM1chr8

17867253

+RETchr10

43619118

+
intron-3CDSENST00000518936ENST00000355710PCM1chr8

17851129

RETchr10

43612030

intron-3CDSENST00000518936ENST00000355710PCM1chr8

17851128

+RETchr10

43612031

+
intron-3CDSENST00000518936ENST00000355710PCM1chr8

17851129

+RETchr10

43612030

+
intron-3CDSENST00000518936ENST00000355710PCM1chr8

17867253

+RETchr10

43619118

+

check buttonORFfinder result based on the fusion transcript sequence of in-frame fusion genes.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandSeq length
(transcript)		BP loci
(transcript)		Predicted start
(transcript)		Predicted stop
(transcript)		Seq length
(amino acids)
ENST00000325083PCM1chr817851128+ENST00000355710RETchr1043612031+8557526643964742011
ENST00000325083PCM1chr817851128+ENST00000340058RETchr1043612031+7099526643963481969
ENST00000519253PCM1chr817851128+ENST00000355710RETchr1043612031+8345505425162622003
ENST00000519253PCM1chr817851128+ENST00000340058RETchr1043612031+6887505425161361961
ENST00000524226PCM1chr817851128+ENST00000355710RETchr1043612031+801547245959321957
ENST00000524226PCM1chr817851128+ENST00000340058RETchr1043612031+655747245958061915
ENST00000327578PCM1chr817851128+ENST00000355710RETchr1043612031+43371046232254743
ENST00000327578PCM1chr817851128+ENST00000340058RETchr1043612031+28791046232128701
ENST00000325083PCM1chr817851129+ENST00000355710RETchr1043612030+8557526643964742011
ENST00000325083PCM1chr817851129+ENST00000340058RETchr1043612030+7099526643963481969
ENST00000519253PCM1chr817851129+ENST00000355710RETchr1043612030+8345505425162622003
ENST00000519253PCM1chr817851129+ENST00000340058RETchr1043612030+6887505425161361961
ENST00000524226PCM1chr817851129+ENST00000355710RETchr1043612030+801547245959321957
ENST00000524226PCM1chr817851129+ENST00000340058RETchr1043612030+655747245958061915
ENST00000327578PCM1chr817851129+ENST00000355710RETchr1043612030+43371046232254743
ENST00000327578PCM1chr817851129+ENST00000340058RETchr1043612030+28791046232128701
ENST00000325083PCM1chr817851129ENST00000355710RETchr10436120308557526643964742011
ENST00000325083PCM1chr817851129ENST00000340058RETchr10436120307099526643963481969
ENST00000519253PCM1chr817851129ENST00000355710RETchr10436120308345505425162622003
ENST00000519253PCM1chr817851129ENST00000340058RETchr10436120306887505425161361961
ENST00000524226PCM1chr817851129ENST00000355710RETchr1043612030801547245959321957
ENST00000524226PCM1chr817851129ENST00000340058RETchr1043612030655747245958061915
ENST00000327578PCM1chr817851129ENST00000355710RETchr104361203043371046232254743
ENST00000327578PCM1chr817851129ENST00000340058RETchr104361203028791046232128701

check buttonDeepORF prediction of the coding potential based on the fusion transcript sequence of in-frame fusion genes. DeepORF is a coding potential classifier based on convolutional neural network by comparing the real Ribo-seq data. If the no-coding score < 0.5 and coding score > 0.5, then the in-frame fusion transcript is predicted as being likely translated.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandNo-coding scoreCoding score
ENST00000325083ENST00000355710PCM1chr817851129RETchr10436120300.0012801470.99871993
ENST00000325083ENST00000340058PCM1chr817851129RETchr10436120300.0029393050.9970607
ENST00000519253ENST00000355710PCM1chr817851129RETchr10436120300.000559980.99944
ENST00000519253ENST00000340058PCM1chr817851129RETchr10436120300.0030330750.9969669
ENST00000524226ENST00000355710PCM1chr817851129RETchr10436120300.0011472870.9988527
ENST00000524226ENST00000340058PCM1chr817851129RETchr10436120300.0015086190.9984914
ENST00000327578ENST00000355710PCM1chr817851129RETchr10436120300.0015422550.9984578
ENST00000327578ENST00000340058PCM1chr817851129RETchr10436120300.0067443090.9932556

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Fusion Genomic Features for PCM1-RET


check buttonFusionAI prediction of the potential fusion gene breakpoint based on the pre-mature RNA sequence context (+/- 5kb of individual partner genes, total 20kb length sequence). FusionAI is a fusion gene breakpoint classifier based on convolutional neural network by comparing the fusion positive and negative sequence context of ~ 20K fusion gene data. From here, we can have the relative potentency of the 20K genomic sequence how individual sequnce will be likely used as the gene fusion breakpoints.
HgeneHchrHbpHstrandTgeneTchrTbpTstrand1-pp (fusion gene breakpoint)
PCM1chr817851128+RETchr1043612031+3.10E-050.999969
PCM1chr817851128+RETchr1043612031+3.10E-050.999969

check buttonDistribution of 44 human genomic features loci across 20kb length fusion breakpoint regions. We integrated a total of 44 different types of human genomic feature loci information across five big categories including virus integration sites, repeats, structural variants, chromatin states, and gene expression regulation. More details are in help page.
genomic feature

check buttonDistribution of 44 human genomic features loci across 20kb length fusion breakpoint regions that are ovelapped with the top 1% feature importance score regions. More details are in help page.
genomic feature of top 1%

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Fusion Protein Features for PCM1-RET


check button Four levels of functional features of fusion genes
Go to FGviewer search page for the most frequent breakpoint (https://ccsmweb.uth.edu/FGviewer/chr8:17851129/chr10:43612030)
- FGviewer provides the online visualization of the retention search of the protein functional features across DNA, RNA, protein, and pathological levels.
- How to search
1. Put your fusion gene symbol.
2. Press the tab key until there will be shown the breakpoint information filled.
4. Go down and press 'Search' tab twice.
4. Go down to have the hyperlink of the search result.
5. Click the hyperlink.
6. See the FGviewer result for your fusion gene.
FGviewer

check buttonMain function of each fusion partner protein. (from UniProt)
HgeneTgene
.RET

RTL1

FUNCTION: Transcriptional activator which is required for calcium-dependent dendritic growth and branching in cortical neurons. Recruits CREB-binding protein (CREBBP) to nuclear bodies. Component of the CREST-BRG1 complex, a multiprotein complex that regulates promoter activation by orchestrating a calcium-dependent release of a repressor complex and a recruitment of an activator complex. In resting neurons, transcription of the c-FOS promoter is inhibited by BRG1-dependent recruitment of a phospho-RB1-HDAC1 repressor complex. Upon calcium influx, RB1 is dephosphorylated by calcineurin, which leads to release of the repressor complex. At the same time, there is increased recruitment of CREBBP to the promoter by a CREST-dependent mechanism, which leads to transcriptional activation. The CREST-BRG1 complex also binds to the NR2B promoter, and activity-dependent induction of NR2B expression involves a release of HDAC1 and recruitment of CREBBP (By similarity). {ECO:0000250}.1358

check buttonRetention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at

download page


* Minus value of BPloci means that the break pointn is located before the CDS.
- In-frame and retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
HgenePCM1chr8:17851129chr10:43612030ENST00000325083+29391063_108916092025.0Coiled coilOntology_term=ECO:0000255
HgenePCM1chr8:17851129chr10:43612030ENST00000325083+29391515_153916092025.0Coiled coilOntology_term=ECO:0000255
HgenePCM1chr8:17851129chr10:43612030ENST00000325083+2939218_30116092025.0Coiled coilOntology_term=ECO:0000255
HgenePCM1chr8:17851129chr10:43612030ENST00000325083+2939400_42416092025.0Coiled coilOntology_term=ECO:0000255
HgenePCM1chr8:17851129chr10:43612030ENST00000325083+2939487_54316092025.0Coiled coilOntology_term=ECO:0000255
HgenePCM1chr8:17851129chr10:43612030ENST00000325083+2939651_68216092025.0Coiled coilOntology_term=ECO:0000255
HgenePCM1chr8:17851129chr10:43612030ENST00000325083+2939726_76916092025.0Coiled coilOntology_term=ECO:0000255
HgenePCM1chr8:17851129chr10:43612030ENST00000325083+2939824_85816092025.0Coiled coilOntology_term=ECO:0000255
TgeneRETchr8:17851129chr10:43612030ENST000003400581019724_10167121073.0DomainProtein kinase
TgeneRETchr8:17851129chr10:43612030ENST000003557101020724_10167121115.0DomainProtein kinase
TgeneRETchr8:17851129chr10:43612030ENST000003400581019730_7387121073.0Nucleotide bindingATP
TgeneRETchr8:17851129chr10:43612030ENST000003557101020730_7387121115.0Nucleotide bindingATP
TgeneRETchr8:17851129chr10:43612030ENST000003400581019805_8077121073.0RegionNote=Inhibitors binding
TgeneRETchr8:17851129chr10:43612030ENST000003557101020805_8077121115.0RegionNote=Inhibitors binding

- In-frame and not-retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
TgeneRETchr8:17851129chr10:43612030ENST000003400581019168_2727121073.0DomainCadherin
TgeneRETchr8:17851129chr10:43612030ENST000003557101020168_2727121115.0DomainCadherin
TgeneRETchr8:17851129chr10:43612030ENST00000340058101929_6357121073.0Topological domainExtracellular
TgeneRETchr8:17851129chr10:43612030ENST000003400581019658_11147121073.0Topological domainCytoplasmic
TgeneRETchr8:17851129chr10:43612030ENST00000355710102029_6357121115.0Topological domainExtracellular
TgeneRETchr8:17851129chr10:43612030ENST000003557101020658_11147121115.0Topological domainCytoplasmic
TgeneRETchr8:17851129chr10:43612030ENST000003400581019636_6577121073.0TransmembraneHelical
TgeneRETchr8:17851129chr10:43612030ENST000003557101020636_6577121115.0TransmembraneHelical


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Fusion Gene Sequence for PCM1-RET


check button For in-frame fusion transcripts, we provide the fusion transcript sequences and fusion amino acid sequences. To have fusion amino acid sequence, we ran ORFfinder and chose the longest ORF among the all predicted ones.
>63341_63341_1_PCM1-RET_PCM1_chr8_17851128_ENST00000325083_RET_chr10_43612031_ENST00000340058_length(transcript)=7099nt_BP=5266nt
TCCGGCGGGTCACATGACTCCAGTCTAGCTCGCATTGCGGCTCCCGCCCGGGCGAGTTCTCGCCCCCGCGCGGCCGTTGCCGAGGAGACG
GCGCATGTCCCGCCGCGCGTTGCCCCCTCTGCAGTACCCCCGCCCCTCTTCTCCCACCACAATGAGATCCTAAGATGGCGGTGGCTGCGG
CGGTTGGCGCTGCGTAGCTGAGGTCGAAAAGGCGGCCACTGGGGCCGAGGCAGCCAGGAAACGTGTGGGCCTCTCTGCTGCGGTCTCCGA
GGGCCGACCGCTGCCGGCGGCGGGTCGTGGGGGCTGACTGTCGCTCTGCCTTTGACAGGAGAGGCTGCTTCTTGTAGAGGAAACAGCTTT
GAAGTGTGGAGCGGGAAAGGAGCAGTTTCTGAGCTGCAAAAACTAGTTTCTAAACAGAGAGTTAATTGTTAAATCCAGTATGGCCACAGG
AGGAGGTCCCTTTGAAGATGGCATGAATGATCAGGATTTACCAAACTGGAGTAATGAGAATGTTGATGACAGGCTCAACAATATGGATTG
GGGTGCCCAACAGAAGAAAGCAAATAGATCATCAGAAAAGAATAAGAAAAAGTTTGGTGTAGAAAGTGATAAAAGAGTAACCAATGATAT
TTCTCCGGAGTCGTCACCAGGAGTTGGAAGGCGAAGAACAAAGACTCCACATACGTTCCCACACAGTAGATACATGAGTCAGATGTCTGT
CCCAGAGCAGGCAGAATTAGAGAAACTGAAACAGCGGATAAACTTCAGTGATTTAGATCAGAGAAGCATTGGAAGTGATTCCCAAGGTAG
AGCAACAGCTGCTAACAACAAACGTCAGCTTAGTGAAAACCGAAAGCCCTTCAACTTTTTGCCTATGCAGATTAATACTAACAAGAGCAA
AGATGCATCTACAAACCCCCCAAACAGAGAAACGATTGGATCAGCACAGTGTAAAGAGTTGTTTGCTTCTGCTTTAAGTAATGACCTCTT
GCAAAACTGTCAGGTGTCTGAAGAAGATGGGAGGGGAGAACCTGCAATGGAGAGCAGCCAGATTGTAAGCAGGCTTGTTCAAATTCGCGA
TTATATTACTAAAGCTAGTTCCATGCGGGAAGATCTTGTAGAGAAAAATGAGAGATCTGCTAATGTTGAGCGCCTTACTCATCTAATAGA
TCACCTTAAAGAACAAGAGAAGTCATATATGAAATTTCTTAAAAAAATCCTTGCCAGAGATCCTCAGCAGGAGCCTATGGAAGAGATAGA
AAATTTGAAGAAACAACATGATTTATTAAAAAGAATGTTACAACAGCAGGAGCAACTAAGAGCTCTACAGGGACGGCAGGCTGCACTTCT
AGCTCTGCAACATAAAGCAGAGCAAGCTATTGCAGTGATGGATGATTCTGTTGTTGCAGAAACTGCAGGTAGCTTATCTGGCGTCAGTAT
CACATCTGAACTAAATGAAGAATTGAATGACTTAATTCAGCGTTTTCATAATCAGCTTCGTGATTCTCAGCCTCCAGCTGTTCCAGACAA
TAGAAGACAGGCAGAAAGTCTTTCATTAACTAGGGAGGTTTCCCAGAGCAGGAAACCATCAGCTTCAGAACGTTTACCTGATGAGAAAGT
CGAACTTTTTAGCAAAATGAGAGTGCTACAGGAAAAGAAACAAAAAATGGACAAATTGCTTGGAGAACTTCATACACTTCGAGATCAGCA
TCTTAACAATTCATCATCCTCTCCACAAAGGAGTGTCGATCAGAGAAGTACTTCAGCTCCCTCTGCTTCTGTAGGCTTGGCACCGGTTGT
CAATGGAGAATCCAATAGCCTCACATCATCTGTTCCTTATCCTACTGCTTCTCTAGTATCTCAGAATGAGAGTGAAAACGAAGGCCACCT
CAATCCATCTGAAAAACTCCAGAAGTTAAATGAAGTTCGAAAGAGATTGAATGAGCTAAGAGAATTAGTTCATTATTATGAACAAACGTC
AGACATGATGACAGATGCTGTGAATGAAAACAGGAAAGATGAAGAAACTGAAGAGTCAGAATATGATTCTGAGCATGAAAATTCCGAGCC
TGTTACTAACATTCGAAATCCACAAGTAGCTTCCACTTGGAATGAAGTAAATAGTCATAGTAATGCACAGTGTGTTTCTAATAATAGAGA
TGGGCGAACAGTTAATTCTAATTGTGAAATTAACAACAGATCTGCTGCCAACATAAGGGCTCTAAACATGCCTCCTTCTTTAGATTGTCG
ATATAATAGAGAAGGGGAACAGGAGATTCATGTTGCACAAGGTGAAGATGATGAGGAGGAGGAGGAAGAAGCAGAAGAGGAGGGAGTCAG
TGGAGCTTCATTATCTAGTCACAGGAGCAGTCTGGTTGATGAGCATCCAGAAGATGCTGAATTTGAACAGAAGATCAACCGACTTATGGC
TGCAAAACAGAAACTTAGACAGTTACAAGATCTTGTTGCTATGGTACAGGATGATGATGCAGCTCAAGGAGTTATCTCTGCCAGTGCATC
AAATTTGGATGATTTCTACCCAGCAGAAGAAGACACCAAGCAAAATTCAAATAACACTAGAGGAAATGCCAATAAAACACAGAAAGATAC
TGGAGTAAATGAAAAGGCAAGAGAGAAATTTTATGAGGCTAAACTACAGCAGCAACAGAGAGAGCTAAAACAATTGCAGGAAGAAAGAAA
GAAACTGATTGACATTCAGGAGAAAATTCAAGCATTGCAAACGGCATGCCCTGACTTACAGCTGTCAGCTGCTAGTGTGGGTAACTGTCC
CACCAAAAAATATATGCCAGCTGTTACTTCAACCCCAACTGTTAATCAACACGAGACCAGTACAAGCAAATCTGTTTTTGAGCCTGAAGA
TTCTTCAATAGTAGATAATGAGTTGTGGTCAGAAATGAGAAGACATGAAATGTTGAGGGAGGAGCTGCGACAGAGAAGAAAGCAGCTTGA
AGCTCTGATGGCTGAACATCAGAGGAGGCAAGGTCTAGCTGAAACTGCATCTCCAGTGGCTGTGTCATTGAGAAGTGATGGATCTGAGAA
CCTATGTACTCCTCAGCAAAGTAGAACAGAAAAAACGATGGCAACTTGGGGAGGGTCTACCCAGTGTGCACTAGATGAAGAAGGAGATGA
AGACGGTTACCTTTCTGAAGGAATTGTTCGGACAGATGAAGAGGAGGAAGAAGAGCAAGATGCCAGTTCCAATGATAACTTTTCTGTGTG
TCCTTCTAACAGTGTGAATCATAACTCCTACAATGGAAAGGAAACTAAAAATAGGTGGAAGAACAATTGCCCTTTTTCGGCAGATGAAAA
TTATCGTCCTTTAGCCAAGACAAGGCAACAGAATATCAGCATGCAACGGCAAGAAAACCTTCGTTGGGTGTCAGAGCTCTCTTACGTAGA
AGAGAAAGAACAATGGCAAGAACAAATCAATCAGCTAAAGAAACAGCTTGATTTTAGTGTCAGTATTTGTCAGACTTTGATGCAAGACCA
GCAGACTCTATCTTGTCTGCTACAAACTCTTCTCACGGGTCCTTACAGTGTTATGCCCAGCAATGTTGCATCTCCTCAAGTACACTTCAT
AATGCACCAGTTGAACCAGTGCTATACTCAGCTAACATGGCAACAGAATAATGTTCAGAGGTTGAAACAAATGCTAAATGAACTTATGCG
CCAGCAAAATCAGCATCCAGAAAAACCTGGAGGCAAGGAAAGAGGCAGTAGTGCATCGCACCCTCCTTCTCCCAGTTTATTTTGTCCTTT
CAGCTTTCCAACACAGCCTGTAAATCTCTTCAATATACCTGGATTTACTAACTTTTCATCATTTGCACCAGGTATGAATTTCAGCCCTTT
ATTTCCTTCTAATTTTGGAGATTTTTCTCAGAATATCTCTACACCCAGTGAACAGCAGCAACCCTTAGCCCAGAATTCTTCAGGAAAAAC
AGAATATATGGCTTTTCCAAAACCTTTTGAAAGCAGTTCCTCTATTGGAGCAGAGAAACCAAGGAATAAAAAACTGCCTGAAGAGGAGGT
GGAAAGCAGTAGGACACCATGGTTATATGAACAAGAAGGTGAAGTAGAGAAACCATTTATCAAGACTGGATTTTCAGTGTCTGTAGAAAA
ATCTACAAGTAGTAACCGCAAAAATCAATTAGATACAAACGGAAGAAGACGCCAGTTTGATGAAGAATCACTGGAAAGCTTTAGCAGTAT
GCCTGATCCAGTAGATCCAACAACAGTGACTAAAACATTCAAGACAAGAAAAGCGTCTGCACAGGCCAGCCTGGCATCTAAAGATAAAAC
TCCCAAGTCAAAAAGTAAGAAGAGGAATTCTACTCAGCTGAAAAGCAGAGTTAAAAACATCAGGTATGAAAGTGCCAGTATGTCTAGCAC
ATGTGAACCTTGCAAAAGTAGGAACAGACATTCAGCCCAGACTGAAGAGCCTGTTCAAGCAAAAGTATTCAGCAGAAAGAATCATGAGCA
ACTGGAAAAAATAATAAAATGTAATAGGTCTACAGAAATATCTTCAGAAACTGGGAGTGATTTTTCCATGTTTGAAGCTTTGCGAGATAC
TATTTATTCTGAAGTAGCTACATTAATTTCTCAAAATGAATCTCGTCCACATTTTCTTATTGAACTCTTCCATGAGCTGCAGCTACTAAA
CACAGACTACTTGAGACAGAGGGCTTTATATGCATTGCAGGACATAGTATCCAGACATATTTCTGAGAGCCATGAAAAAGGAGAAAATGT
AAAGTCAGTAAACTCTGGTACTTGGATAGCATCAAACTCAGAACTTACTCCTAGTGAGAGCCTTGCTACTACTGATGATGAAACTTTTGA
GAAGAACTTTGAAAGAGAAACCCATAAAATAAGTGAGCAAAATGATGCTGATAATGCTAGTGTCCTGTCTGTATCATCAAATTTTGAGCC
TTTTGCAACAGATGATCTAGGTAACACCGTGATTCACTTAGATCAAGCATTAGCCAGAATGAGAGAATATGAGCGTATGAAGACTGAGGC
TGAAAGTAACTCAAATATGAGATGCACCTGCAGGATTATTGAGGATGGAGATGGTGCTGGTGCAGGTACTACAGTTAATAATTTAGAAGA
AACTCCCGTTATTGAAAATCGTAGTTCACAACAACCTGTAAGTGAAGTTTCTACCATCCCATGTCCTAGAATTGATACTCAGCAGCTGGA
CCGGCAAATTAAAGCAATTATGAAAGAAGTCATTCCTTTTTTGAAGGAGGATCCAAAGTGGGAATTCCCTCGGAAGAACTTGGTTCTTGG
AAAAACTCTAGGAGAAGGCGAATTTGGAAAAGTGGTCAAGGCAACGGCCTTCCATCTGAAAGGCAGAGCAGGGTACACCACGGTGGCCGT
GAAGATGCTGAAAGAGAACGCCTCCCCGAGTGAGCTGCGAGACCTGCTGTCAGAGTTCAACGTCCTGAAGCAGGTCAACCACCCACATGT
CATCAAATTGTATGGGGCCTGCAGCCAGGATGGCCCGCTCCTCCTCATCGTGGAGTACGCCAAATACGGCTCCCTGCGGGGCTTCCTCCG
CGAGAGCCGCAAAGTGGGGCCTGGCTACCTGGGCAGTGGAGGCAGCCGCAACTCCAGCTCCCTGGACCACCCGGATGAGCGGGCCCTCAC
CATGGGCGACCTCATCTCATTTGCCTGGCAGATCTCACAGGGGATGCAGTATCTGGCCGAGATGAAGCTCGTTCATCGGGACTTGGCAGC
CAGAAACATCCTGGTAGCTGAGGGGCGGAAGATGAAGATTTCGGATTTCGGCTTGTCCCGAGATGTTTATGAAGAGGATTCCTACGTGAA
GAGGAGCCAGGGTCGGATTCCAGTTAAATGGATGGCAATTGAATCCCTTTTTGATCATATCTACACCACGCAAAGTGATGTATGGTCTTT
TGGTGTCCTGCTGTGGGAGATCGTGACCCTAGGGGGAAACCCCTATCCTGGGATTCCTCCTGAGCGGCTCTTCAACCTTCTGAAGACCGG
CCACCGGATGGAGAGGCCAGACAACTGCAGCGAGGAGATGTACCGCCTGATGCTGCAATGCTGGAAGCAGGAGCCGGACAAAAGGCCGGT
GTTTGCGGACATCAGCAAAGACCTGGAGAAGATGATGGTTAAGAGGAGAGACTACTTGGACCTTGCGGCGTCCACTCCATCTGACTCCCT
GATTTATGACGACGGCCTCTCAGAGGAGGAGACACCGCTGGTGGACTGTAATAATGCCCCCCTCCCTCGAGCCCTCCCTTCCACATGGAT
TGAAAACAAACTCTATGGTAGAATTTCCCATGCATTTACTAGATTCTAGCACCGCTGTCCCCTTTGCACTATCCTTCCTCTCTGTGATGC
TTTTTAAAAATGTTTCTGGTCTGAACAAAACCAAAGTCTGCTCTGAACCTTTTTATTTGTAAATGTCTGACTTTGCATCCAGTTTACATT
TAGGCATTATTGCAACTATGTTTTTCTAAAAGGATGTGAAAATAAGTGTAATTACCACATTGCCCAGCAACTTAGGATGGTAGAGGAAAA
AACAGATCAGGGCGGAACTCTCAGGGGAGACCAAGAACAGGTTGAATAAGGCGCTTCTGGGGTGGGAATCAAGTCATAGTACTTCTACTT
TAACTAAGTGGATAAATATACAAATCTGGGGAGGTATTCAGTTGAGAAAGGAGCCACCAGCACCACTCAGCCTGCACTGGGAGCACAGCC
AGGTTCCCCCAGACCCCTCCTGGGCAGGCAGGTGCCTCTCAGAGGCCACCCGGCACTGGCGAGCAGCCACTGGCCAAGCCTCAGCCCCAG
TCCCAGCCACATGTCCTCCATCAGGGGTAGCGAGGTTGCAGGAGCTGGCTGGCCCTGGGAGGACGCACCCCCACTGCTGTTTTCACATCC
TTTCCCTTACCCACCTTCAGGACGGTTGTCACTTATGAAGTCAGTGCTAAAGCTGGAGCAGTTGCTTTTTGAAAGAACATGGTCTGTGGT

>63341_63341_1_PCM1-RET_PCM1_chr8_17851128_ENST00000325083_RET_chr10_43612031_ENST00000340058_length(amino acids)=1969AA_BP=1609
MATGGGPFEDGMNDQDLPNWSNENVDDRLNNMDWGAQQKKANRSSEKNKKKFGVESDKRVTNDISPESSPGVGRRRTKTPHTFPHSRYMS
QMSVPEQAELEKLKQRINFSDLDQRSIGSDSQGRATAANNKRQLSENRKPFNFLPMQINTNKSKDASTNPPNRETIGSAQCKELFASALS
NDLLQNCQVSEEDGRGEPAMESSQIVSRLVQIRDYITKASSMREDLVEKNERSANVERLTHLIDHLKEQEKSYMKFLKKILARDPQQEPM
EEIENLKKQHDLLKRMLQQQEQLRALQGRQAALLALQHKAEQAIAVMDDSVVAETAGSLSGVSITSELNEELNDLIQRFHNQLRDSQPPA
VPDNRRQAESLSLTREVSQSRKPSASERLPDEKVELFSKMRVLQEKKQKMDKLLGELHTLRDQHLNNSSSSPQRSVDQRSTSAPSASVGL
APVVNGESNSLTSSVPYPTASLVSQNESENEGHLNPSEKLQKLNEVRKRLNELRELVHYYEQTSDMMTDAVNENRKDEETEESEYDSEHE
NSEPVTNIRNPQVASTWNEVNSHSNAQCVSNNRDGRTVNSNCEINNRSAANIRALNMPPSLDCRYNREGEQEIHVAQGEDDEEEEEEAEE
EGVSGASLSSHRSSLVDEHPEDAEFEQKINRLMAAKQKLRQLQDLVAMVQDDDAAQGVISASASNLDDFYPAEEDTKQNSNNTRGNANKT
QKDTGVNEKAREKFYEAKLQQQQRELKQLQEERKKLIDIQEKIQALQTACPDLQLSAASVGNCPTKKYMPAVTSTPTVNQHETSTSKSVF
EPEDSSIVDNELWSEMRRHEMLREELRQRRKQLEALMAEHQRRQGLAETASPVAVSLRSDGSENLCTPQQSRTEKTMATWGGSTQCALDE
EGDEDGYLSEGIVRTDEEEEEEQDASSNDNFSVCPSNSVNHNSYNGKETKNRWKNNCPFSADENYRPLAKTRQQNISMQRQENLRWVSEL
SYVEEKEQWQEQINQLKKQLDFSVSICQTLMQDQQTLSCLLQTLLTGPYSVMPSNVASPQVHFIMHQLNQCYTQLTWQQNNVQRLKQMLN
ELMRQQNQHPEKPGGKERGSSASHPPSPSLFCPFSFPTQPVNLFNIPGFTNFSSFAPGMNFSPLFPSNFGDFSQNISTPSEQQQPLAQNS
SGKTEYMAFPKPFESSSSIGAEKPRNKKLPEEEVESSRTPWLYEQEGEVEKPFIKTGFSVSVEKSTSSNRKNQLDTNGRRRQFDEESLES
FSSMPDPVDPTTVTKTFKTRKASAQASLASKDKTPKSKSKKRNSTQLKSRVKNIRYESASMSSTCEPCKSRNRHSAQTEEPVQAKVFSRK
NHEQLEKIIKCNRSTEISSETGSDFSMFEALRDTIYSEVATLISQNESRPHFLIELFHELQLLNTDYLRQRALYALQDIVSRHISESHEK
GENVKSVNSGTWIASNSELTPSESLATTDDETFEKNFERETHKISEQNDADNASVLSVSSNFEPFATDDLGNTVIHLDQALARMREYERM
KTEAESNSNMRCTCRIIEDGDGAGAGTTVNNLEETPVIENRSSQQPVSEVSTIPCPRIDTQQLDRQIKAIMKEVIPFLKEDPKWEFPRKN
LVLGKTLGEGEFGKVVKATAFHLKGRAGYTTVAVKMLKENASPSELRDLLSEFNVLKQVNHPHVIKLYGACSQDGPLLLIVEYAKYGSLR
GFLRESRKVGPGYLGSGGSRNSSSLDHPDERALTMGDLISFAWQISQGMQYLAEMKLVHRDLAARNILVAEGRKMKISDFGLSRDVYEED
SYVKRSQGRIPVKWMAIESLFDHIYTTQSDVWSFGVLLWEIVTLGGNPYPGIPPERLFNLLKTGHRMERPDNCSEEMYRLMLQCWKQEPD

--------------------------------------------------------------
>63341_63341_2_PCM1-RET_PCM1_chr8_17851128_ENST00000325083_RET_chr10_43612031_ENST00000355710_length(transcript)=8557nt_BP=5266nt
TCCGGCGGGTCACATGACTCCAGTCTAGCTCGCATTGCGGCTCCCGCCCGGGCGAGTTCTCGCCCCCGCGCGGCCGTTGCCGAGGAGACG
GCGCATGTCCCGCCGCGCGTTGCCCCCTCTGCAGTACCCCCGCCCCTCTTCTCCCACCACAATGAGATCCTAAGATGGCGGTGGCTGCGG
CGGTTGGCGCTGCGTAGCTGAGGTCGAAAAGGCGGCCACTGGGGCCGAGGCAGCCAGGAAACGTGTGGGCCTCTCTGCTGCGGTCTCCGA
GGGCCGACCGCTGCCGGCGGCGGGTCGTGGGGGCTGACTGTCGCTCTGCCTTTGACAGGAGAGGCTGCTTCTTGTAGAGGAAACAGCTTT
GAAGTGTGGAGCGGGAAAGGAGCAGTTTCTGAGCTGCAAAAACTAGTTTCTAAACAGAGAGTTAATTGTTAAATCCAGTATGGCCACAGG
AGGAGGTCCCTTTGAAGATGGCATGAATGATCAGGATTTACCAAACTGGAGTAATGAGAATGTTGATGACAGGCTCAACAATATGGATTG
GGGTGCCCAACAGAAGAAAGCAAATAGATCATCAGAAAAGAATAAGAAAAAGTTTGGTGTAGAAAGTGATAAAAGAGTAACCAATGATAT
TTCTCCGGAGTCGTCACCAGGAGTTGGAAGGCGAAGAACAAAGACTCCACATACGTTCCCACACAGTAGATACATGAGTCAGATGTCTGT
CCCAGAGCAGGCAGAATTAGAGAAACTGAAACAGCGGATAAACTTCAGTGATTTAGATCAGAGAAGCATTGGAAGTGATTCCCAAGGTAG
AGCAACAGCTGCTAACAACAAACGTCAGCTTAGTGAAAACCGAAAGCCCTTCAACTTTTTGCCTATGCAGATTAATACTAACAAGAGCAA
AGATGCATCTACAAACCCCCCAAACAGAGAAACGATTGGATCAGCACAGTGTAAAGAGTTGTTTGCTTCTGCTTTAAGTAATGACCTCTT
GCAAAACTGTCAGGTGTCTGAAGAAGATGGGAGGGGAGAACCTGCAATGGAGAGCAGCCAGATTGTAAGCAGGCTTGTTCAAATTCGCGA
TTATATTACTAAAGCTAGTTCCATGCGGGAAGATCTTGTAGAGAAAAATGAGAGATCTGCTAATGTTGAGCGCCTTACTCATCTAATAGA
TCACCTTAAAGAACAAGAGAAGTCATATATGAAATTTCTTAAAAAAATCCTTGCCAGAGATCCTCAGCAGGAGCCTATGGAAGAGATAGA
AAATTTGAAGAAACAACATGATTTATTAAAAAGAATGTTACAACAGCAGGAGCAACTAAGAGCTCTACAGGGACGGCAGGCTGCACTTCT
AGCTCTGCAACATAAAGCAGAGCAAGCTATTGCAGTGATGGATGATTCTGTTGTTGCAGAAACTGCAGGTAGCTTATCTGGCGTCAGTAT
CACATCTGAACTAAATGAAGAATTGAATGACTTAATTCAGCGTTTTCATAATCAGCTTCGTGATTCTCAGCCTCCAGCTGTTCCAGACAA
TAGAAGACAGGCAGAAAGTCTTTCATTAACTAGGGAGGTTTCCCAGAGCAGGAAACCATCAGCTTCAGAACGTTTACCTGATGAGAAAGT
CGAACTTTTTAGCAAAATGAGAGTGCTACAGGAAAAGAAACAAAAAATGGACAAATTGCTTGGAGAACTTCATACACTTCGAGATCAGCA
TCTTAACAATTCATCATCCTCTCCACAAAGGAGTGTCGATCAGAGAAGTACTTCAGCTCCCTCTGCTTCTGTAGGCTTGGCACCGGTTGT
CAATGGAGAATCCAATAGCCTCACATCATCTGTTCCTTATCCTACTGCTTCTCTAGTATCTCAGAATGAGAGTGAAAACGAAGGCCACCT
CAATCCATCTGAAAAACTCCAGAAGTTAAATGAAGTTCGAAAGAGATTGAATGAGCTAAGAGAATTAGTTCATTATTATGAACAAACGTC
AGACATGATGACAGATGCTGTGAATGAAAACAGGAAAGATGAAGAAACTGAAGAGTCAGAATATGATTCTGAGCATGAAAATTCCGAGCC
TGTTACTAACATTCGAAATCCACAAGTAGCTTCCACTTGGAATGAAGTAAATAGTCATAGTAATGCACAGTGTGTTTCTAATAATAGAGA
TGGGCGAACAGTTAATTCTAATTGTGAAATTAACAACAGATCTGCTGCCAACATAAGGGCTCTAAACATGCCTCCTTCTTTAGATTGTCG
ATATAATAGAGAAGGGGAACAGGAGATTCATGTTGCACAAGGTGAAGATGATGAGGAGGAGGAGGAAGAAGCAGAAGAGGAGGGAGTCAG
TGGAGCTTCATTATCTAGTCACAGGAGCAGTCTGGTTGATGAGCATCCAGAAGATGCTGAATTTGAACAGAAGATCAACCGACTTATGGC
TGCAAAACAGAAACTTAGACAGTTACAAGATCTTGTTGCTATGGTACAGGATGATGATGCAGCTCAAGGAGTTATCTCTGCCAGTGCATC
AAATTTGGATGATTTCTACCCAGCAGAAGAAGACACCAAGCAAAATTCAAATAACACTAGAGGAAATGCCAATAAAACACAGAAAGATAC
TGGAGTAAATGAAAAGGCAAGAGAGAAATTTTATGAGGCTAAACTACAGCAGCAACAGAGAGAGCTAAAACAATTGCAGGAAGAAAGAAA
GAAACTGATTGACATTCAGGAGAAAATTCAAGCATTGCAAACGGCATGCCCTGACTTACAGCTGTCAGCTGCTAGTGTGGGTAACTGTCC
CACCAAAAAATATATGCCAGCTGTTACTTCAACCCCAACTGTTAATCAACACGAGACCAGTACAAGCAAATCTGTTTTTGAGCCTGAAGA
TTCTTCAATAGTAGATAATGAGTTGTGGTCAGAAATGAGAAGACATGAAATGTTGAGGGAGGAGCTGCGACAGAGAAGAAAGCAGCTTGA
AGCTCTGATGGCTGAACATCAGAGGAGGCAAGGTCTAGCTGAAACTGCATCTCCAGTGGCTGTGTCATTGAGAAGTGATGGATCTGAGAA
CCTATGTACTCCTCAGCAAAGTAGAACAGAAAAAACGATGGCAACTTGGGGAGGGTCTACCCAGTGTGCACTAGATGAAGAAGGAGATGA
AGACGGTTACCTTTCTGAAGGAATTGTTCGGACAGATGAAGAGGAGGAAGAAGAGCAAGATGCCAGTTCCAATGATAACTTTTCTGTGTG
TCCTTCTAACAGTGTGAATCATAACTCCTACAATGGAAAGGAAACTAAAAATAGGTGGAAGAACAATTGCCCTTTTTCGGCAGATGAAAA
TTATCGTCCTTTAGCCAAGACAAGGCAACAGAATATCAGCATGCAACGGCAAGAAAACCTTCGTTGGGTGTCAGAGCTCTCTTACGTAGA
AGAGAAAGAACAATGGCAAGAACAAATCAATCAGCTAAAGAAACAGCTTGATTTTAGTGTCAGTATTTGTCAGACTTTGATGCAAGACCA
GCAGACTCTATCTTGTCTGCTACAAACTCTTCTCACGGGTCCTTACAGTGTTATGCCCAGCAATGTTGCATCTCCTCAAGTACACTTCAT
AATGCACCAGTTGAACCAGTGCTATACTCAGCTAACATGGCAACAGAATAATGTTCAGAGGTTGAAACAAATGCTAAATGAACTTATGCG
CCAGCAAAATCAGCATCCAGAAAAACCTGGAGGCAAGGAAAGAGGCAGTAGTGCATCGCACCCTCCTTCTCCCAGTTTATTTTGTCCTTT
CAGCTTTCCAACACAGCCTGTAAATCTCTTCAATATACCTGGATTTACTAACTTTTCATCATTTGCACCAGGTATGAATTTCAGCCCTTT
ATTTCCTTCTAATTTTGGAGATTTTTCTCAGAATATCTCTACACCCAGTGAACAGCAGCAACCCTTAGCCCAGAATTCTTCAGGAAAAAC
AGAATATATGGCTTTTCCAAAACCTTTTGAAAGCAGTTCCTCTATTGGAGCAGAGAAACCAAGGAATAAAAAACTGCCTGAAGAGGAGGT
GGAAAGCAGTAGGACACCATGGTTATATGAACAAGAAGGTGAAGTAGAGAAACCATTTATCAAGACTGGATTTTCAGTGTCTGTAGAAAA
ATCTACAAGTAGTAACCGCAAAAATCAATTAGATACAAACGGAAGAAGACGCCAGTTTGATGAAGAATCACTGGAAAGCTTTAGCAGTAT
GCCTGATCCAGTAGATCCAACAACAGTGACTAAAACATTCAAGACAAGAAAAGCGTCTGCACAGGCCAGCCTGGCATCTAAAGATAAAAC
TCCCAAGTCAAAAAGTAAGAAGAGGAATTCTACTCAGCTGAAAAGCAGAGTTAAAAACATCAGGTATGAAAGTGCCAGTATGTCTAGCAC
ATGTGAACCTTGCAAAAGTAGGAACAGACATTCAGCCCAGACTGAAGAGCCTGTTCAAGCAAAAGTATTCAGCAGAAAGAATCATGAGCA
ACTGGAAAAAATAATAAAATGTAATAGGTCTACAGAAATATCTTCAGAAACTGGGAGTGATTTTTCCATGTTTGAAGCTTTGCGAGATAC
TATTTATTCTGAAGTAGCTACATTAATTTCTCAAAATGAATCTCGTCCACATTTTCTTATTGAACTCTTCCATGAGCTGCAGCTACTAAA
CACAGACTACTTGAGACAGAGGGCTTTATATGCATTGCAGGACATAGTATCCAGACATATTTCTGAGAGCCATGAAAAAGGAGAAAATGT
AAAGTCAGTAAACTCTGGTACTTGGATAGCATCAAACTCAGAACTTACTCCTAGTGAGAGCCTTGCTACTACTGATGATGAAACTTTTGA
GAAGAACTTTGAAAGAGAAACCCATAAAATAAGTGAGCAAAATGATGCTGATAATGCTAGTGTCCTGTCTGTATCATCAAATTTTGAGCC
TTTTGCAACAGATGATCTAGGTAACACCGTGATTCACTTAGATCAAGCATTAGCCAGAATGAGAGAATATGAGCGTATGAAGACTGAGGC
TGAAAGTAACTCAAATATGAGATGCACCTGCAGGATTATTGAGGATGGAGATGGTGCTGGTGCAGGTACTACAGTTAATAATTTAGAAGA
AACTCCCGTTATTGAAAATCGTAGTTCACAACAACCTGTAAGTGAAGTTTCTACCATCCCATGTCCTAGAATTGATACTCAGCAGCTGGA
CCGGCAAATTAAAGCAATTATGAAAGAAGTCATTCCTTTTTTGAAGGAGGATCCAAAGTGGGAATTCCCTCGGAAGAACTTGGTTCTTGG
AAAAACTCTAGGAGAAGGCGAATTTGGAAAAGTGGTCAAGGCAACGGCCTTCCATCTGAAAGGCAGAGCAGGGTACACCACGGTGGCCGT
GAAGATGCTGAAAGAGAACGCCTCCCCGAGTGAGCTGCGAGACCTGCTGTCAGAGTTCAACGTCCTGAAGCAGGTCAACCACCCACATGT
CATCAAATTGTATGGGGCCTGCAGCCAGGATGGCCCGCTCCTCCTCATCGTGGAGTACGCCAAATACGGCTCCCTGCGGGGCTTCCTCCG
CGAGAGCCGCAAAGTGGGGCCTGGCTACCTGGGCAGTGGAGGCAGCCGCAACTCCAGCTCCCTGGACCACCCGGATGAGCGGGCCCTCAC
CATGGGCGACCTCATCTCATTTGCCTGGCAGATCTCACAGGGGATGCAGTATCTGGCCGAGATGAAGCTCGTTCATCGGGACTTGGCAGC
CAGAAACATCCTGGTAGCTGAGGGGCGGAAGATGAAGATTTCGGATTTCGGCTTGTCCCGAGATGTTTATGAAGAGGATTCCTACGTGAA
GAGGAGCCAGGGTCGGATTCCAGTTAAATGGATGGCAATTGAATCCCTTTTTGATCATATCTACACCACGCAAAGTGATGTATGGTCTTT
TGGTGTCCTGCTGTGGGAGATCGTGACCCTAGGGGGAAACCCCTATCCTGGGATTCCTCCTGAGCGGCTCTTCAACCTTCTGAAGACCGG
CCACCGGATGGAGAGGCCAGACAACTGCAGCGAGGAGATGTACCGCCTGATGCTGCAATGCTGGAAGCAGGAGCCGGACAAAAGGCCGGT
GTTTGCGGACATCAGCAAAGACCTGGAGAAGATGATGGTTAAGAGGAGAGACTACTTGGACCTTGCGGCGTCCACTCCATCTGACTCCCT
GATTTATGACGACGGCCTCTCAGAGGAGGAGACACCGCTGGTGGACTGTAATAATGCCCCCCTCCCTCGAGCCCTCCCTTCCACATGGAT
TGAAAACAAACTCTATGGCATGTCAGACCCGAACTGGCCTGGAGAGAGTCCTGTACCACTCACGAGAGCTGATGGCACTAACACTGGGTT
TCCAAGATATCCAAATGATAGTGTATATGCTAACTGGATGCTTTCACCCTCAGCGGCAAAATTAATGGACACGTTTGATAGTTAACATTT
CTTTGTGAAAGGTAATGGACTCACAAGGGGAAGAAACATGCTGAGAATGGAAAGTCTACCGGCCCTTTCTTTGTGAACGTCACATTGGCC
GAGCCGTGTTCAGTTCCCAGGTGGCAGACTCGTTTTTGGTAGTTTGTTTTAACTTCCAAGGTGGTTTTACTTCTGATAGCCGGTGATTTT
CCCTCCTAGCAGACATGCCACACCGGGTAAGAGCTCTGAGTCTTAGTGGTTAAGCATTCCTTTCTCTTCAGTGCCCAGCAGCACCCAGTG
TTGGTCTGTGTCCATCAGTGACCACCAACATTCTGTGTTCACATGTGTGGGTCCAACACTTACTACCTGGTGTATGAAATTGGACCTGAA
CTGTTGGATTTTTCTAGTTGCCGCCAAACAAGGCAAAAAAATTTAAACATGAAGCACACACACAAAAAAGGCAGTAGGAAAAATGCTGGC
CCTGATGACCTGTCCTTATTCAGAATGAGAGACTGCGGGGGGGGCCTGGGGGTAGTGTCAATGCCCCTCCAGGGCTGGAGGGGAAGAGGG
GCCCCGAGGATGGGCCTGGGCTCAGCATTCGAGATCTTGAGAATGATTTTTTTTAAATCATGCAACCTTTCCTTAGGAAGACATTTGGTT
TTCATCATGATTAAGATGATTCCTAGATTTAGCACAATGGAGAGATTCCATGCCATCTTTACTATGTGGATGGTGGTATCAGGGAAGAGG
GCTCACAAGACACATTTGTCCCCCGGGCCCACCACATCATCCTCACGTGTTCGGTACTGAGCAGCCACTACCCCTGATGAGAACAGTATG
AAGAAAGGGGGCTGTTGGAGTCCCAGAATTGCTGACAGCAGAGGCTTTGCTGCTGTGAATCCCACCTGCCACCAGCCTGCAGCACACCCC
ACAGCCAAGTAGAGGCGAAAGCAGTGGCTCATCCTACCTGTTAGGAGCAGGTAGGGCTTGTACTCACTTTAATTTGAATCTTATCAACTT
ACTCATAAAGGGACAGGCTAGCTAGCTGTGTTAGAAGTAGCAATGACAATGACCAAGGACTGCTACACCTCTGATTACAATTCTGATGTG
AAAAAGATGGTGTTTGGCTCTTATAGAGCCTGTGTGAAAGGCCCATGGATCAGCTCTTCCTGTGTTTGTAATTTAATGCTGCTACAAGAT
GTTTCTGTTTCTTAGATTCTGACCATGACTCATAAGCTTCTTGTCATTCTTCATTGCTTGTTTGTGGTCACAGATGCACAACACTCCTCC
AGTCTTGTGGGGGCAGCTTTTGGGAAGTCTCAGCAGCTCTTCTGGCTGTGTTGTCAGCACTGTAACTTCGCAGAAAAGAGTCGGATTACC
AAAACACTGCCTGCTCTTCAGACTTAAAGCACTGATAGGACTTAAAATAGTCTCATTCAAATACTGTATTTTATATAGGCATTTCACAAA
AACAGCAAAATTGTGGCATTTTGTGAGGCCAAGGCTTGGATGCGTGTGTAATAGAGCCTTGTGGTGTGTGCGCACACACCCAGAGGGAGA
GTTTGAAAAATGCTTATTGGACACGTAACCTGGCTCTAATTTGGGCTGTTTTTCAGATACACTGTGATAAGTTCTTTTACAAATATCTAT
AGACATGGTAAACTTTTGGTTTTCAGATATGCTTAATGATAGTCTTACTAAATGCAGAAATAAGAATAAACTTTCTCAAATTATTAAAAA
TGCCTACACAGTAAGTGTGAATTGCTGCAACAGGTTTGTTCTCAGGAGGGTAAGAACTCCAGGTCTAAACAGCTGACCCAGTGATGGGGA
ATTTATCCTTGACCAATTTATCCTTGACCAATAACCTAATTGTCTATTCCTGAGTTATAAAAGTCCCCATCCTTATTAGCTCTACTGGAA
TTTTCATACACGTAAATGCAGAAGTTACTAAGTATTAAGTATTACTGAGTATTAAGTAGTAATCTGTCAGTTATTAAAATTTGTAAAATC
TATTTATGAAAGGTCATTAAACCAGATCATGTTCCTTTTTTTGTAATCAAGGTGACTAAGAAAATCAGTTGTGTAAATAAAATCATGTAT

>63341_63341_2_PCM1-RET_PCM1_chr8_17851128_ENST00000325083_RET_chr10_43612031_ENST00000355710_length(amino acids)=2011AA_BP=1609
MATGGGPFEDGMNDQDLPNWSNENVDDRLNNMDWGAQQKKANRSSEKNKKKFGVESDKRVTNDISPESSPGVGRRRTKTPHTFPHSRYMS
QMSVPEQAELEKLKQRINFSDLDQRSIGSDSQGRATAANNKRQLSENRKPFNFLPMQINTNKSKDASTNPPNRETIGSAQCKELFASALS
NDLLQNCQVSEEDGRGEPAMESSQIVSRLVQIRDYITKASSMREDLVEKNERSANVERLTHLIDHLKEQEKSYMKFLKKILARDPQQEPM
EEIENLKKQHDLLKRMLQQQEQLRALQGRQAALLALQHKAEQAIAVMDDSVVAETAGSLSGVSITSELNEELNDLIQRFHNQLRDSQPPA
VPDNRRQAESLSLTREVSQSRKPSASERLPDEKVELFSKMRVLQEKKQKMDKLLGELHTLRDQHLNNSSSSPQRSVDQRSTSAPSASVGL
APVVNGESNSLTSSVPYPTASLVSQNESENEGHLNPSEKLQKLNEVRKRLNELRELVHYYEQTSDMMTDAVNENRKDEETEESEYDSEHE
NSEPVTNIRNPQVASTWNEVNSHSNAQCVSNNRDGRTVNSNCEINNRSAANIRALNMPPSLDCRYNREGEQEIHVAQGEDDEEEEEEAEE
EGVSGASLSSHRSSLVDEHPEDAEFEQKINRLMAAKQKLRQLQDLVAMVQDDDAAQGVISASASNLDDFYPAEEDTKQNSNNTRGNANKT
QKDTGVNEKAREKFYEAKLQQQQRELKQLQEERKKLIDIQEKIQALQTACPDLQLSAASVGNCPTKKYMPAVTSTPTVNQHETSTSKSVF
EPEDSSIVDNELWSEMRRHEMLREELRQRRKQLEALMAEHQRRQGLAETASPVAVSLRSDGSENLCTPQQSRTEKTMATWGGSTQCALDE
EGDEDGYLSEGIVRTDEEEEEEQDASSNDNFSVCPSNSVNHNSYNGKETKNRWKNNCPFSADENYRPLAKTRQQNISMQRQENLRWVSEL
SYVEEKEQWQEQINQLKKQLDFSVSICQTLMQDQQTLSCLLQTLLTGPYSVMPSNVASPQVHFIMHQLNQCYTQLTWQQNNVQRLKQMLN
ELMRQQNQHPEKPGGKERGSSASHPPSPSLFCPFSFPTQPVNLFNIPGFTNFSSFAPGMNFSPLFPSNFGDFSQNISTPSEQQQPLAQNS
SGKTEYMAFPKPFESSSSIGAEKPRNKKLPEEEVESSRTPWLYEQEGEVEKPFIKTGFSVSVEKSTSSNRKNQLDTNGRRRQFDEESLES
FSSMPDPVDPTTVTKTFKTRKASAQASLASKDKTPKSKSKKRNSTQLKSRVKNIRYESASMSSTCEPCKSRNRHSAQTEEPVQAKVFSRK
NHEQLEKIIKCNRSTEISSETGSDFSMFEALRDTIYSEVATLISQNESRPHFLIELFHELQLLNTDYLRQRALYALQDIVSRHISESHEK
GENVKSVNSGTWIASNSELTPSESLATTDDETFEKNFERETHKISEQNDADNASVLSVSSNFEPFATDDLGNTVIHLDQALARMREYERM
KTEAESNSNMRCTCRIIEDGDGAGAGTTVNNLEETPVIENRSSQQPVSEVSTIPCPRIDTQQLDRQIKAIMKEVIPFLKEDPKWEFPRKN
LVLGKTLGEGEFGKVVKATAFHLKGRAGYTTVAVKMLKENASPSELRDLLSEFNVLKQVNHPHVIKLYGACSQDGPLLLIVEYAKYGSLR
GFLRESRKVGPGYLGSGGSRNSSSLDHPDERALTMGDLISFAWQISQGMQYLAEMKLVHRDLAARNILVAEGRKMKISDFGLSRDVYEED
SYVKRSQGRIPVKWMAIESLFDHIYTTQSDVWSFGVLLWEIVTLGGNPYPGIPPERLFNLLKTGHRMERPDNCSEEMYRLMLQCWKQEPD
KRPVFADISKDLEKMMVKRRDYLDLAASTPSDSLIYDDGLSEEETPLVDCNNAPLPRALPSTWIENKLYGMSDPNWPGESPVPLTRADGT

--------------------------------------------------------------
>63341_63341_3_PCM1-RET_PCM1_chr8_17851128_ENST00000327578_RET_chr10_43612031_ENST00000340058_length(transcript)=2879nt_BP=1046nt
GAAAAGCGTCTGCACAGGCCAGCCTGGCATCTAAAGATAAAACTCCCAAGTCAAAAAGTAAGAAGAGGAATTCTACTCAGCTGAAAAGCA
GAGTTAAAAACATCAGGTATGAAAGTGCCAGTATGTCTAGCACATGTGAACCTTGCAAAAGTAGGAACAGACATTCAGCCCAGACTGAAG
AGCCTGTTCAAGCAAAAGTATTCAGCAGAAAGAATCATGAGCAACTGGAAAAAATAATAAAATGTAATAGGTCTACAGAAATATCTTCAG
CACATGCTAGGAGAATACTACAGCAGTCTAACAGAAATGCATGCAATGAAGCGCCAGAAACTGGGAGTGATTTTTCCATGTTTGAAGCTT
TGCGAGATACTATTTATTCTGAAGTAGCTACATTAATTTCTCAAAATGAATCTCGTCCACATTTTCTTATTGAACTCTTCCATGAGCTGC
AGCTACTAAACACAGACTACTTGAGACAGAGGGCTTTATATGCATTGCAGGACATAGTATCCAGACATATTTCTGAGAGCCATGAAAAAG
GAGAAAATGTAAAGTCAGTAAACTCTGGTACTTGGATAGCATCAAACTCAGAACTTACTCCTAGTGAGAGCCTTGCTACTACTGATGATG
AAACTTTTGAGAAGAACTTTGAAAGAGAAACCCATAAAATAAGTGAGCAAAATGATGCTGATAATGCTAGTGTCCTGTCTGTATCATCAA
ATTTTGAGCCTTTTGCAACAGATGATCTAGGTAACACCGTGATTCACTTAGATCAAGCATTAGCCAGAATGAGAGAATATGAGCGTATGA
AGACTGAGGCTGAAAGTAACTCAAATATGAGATGCACCTGCAGGATTATTGAGGATGGAGATGGTGCTGGTGCAGGTACTACAGTTAATA
ATTTAGAAGAAACTCCCGTTATTGAAAATCGTAGTTCACAACAACCTGTAAGTGAAGTTTCTACCATCCCATGTCCTAGAATTGATACTC
AGCAGCTGGACCGGCAAATTAAAGCAATTATGAAAGAAGTCATTCCTTTTTTGAAGGAGGATCCAAAGTGGGAATTCCCTCGGAAGAACT
TGGTTCTTGGAAAAACTCTAGGAGAAGGCGAATTTGGAAAAGTGGTCAAGGCAACGGCCTTCCATCTGAAAGGCAGAGCAGGGTACACCA
CGGTGGCCGTGAAGATGCTGAAAGAGAACGCCTCCCCGAGTGAGCTGCGAGACCTGCTGTCAGAGTTCAACGTCCTGAAGCAGGTCAACC
ACCCACATGTCATCAAATTGTATGGGGCCTGCAGCCAGGATGGCCCGCTCCTCCTCATCGTGGAGTACGCCAAATACGGCTCCCTGCGGG
GCTTCCTCCGCGAGAGCCGCAAAGTGGGGCCTGGCTACCTGGGCAGTGGAGGCAGCCGCAACTCCAGCTCCCTGGACCACCCGGATGAGC
GGGCCCTCACCATGGGCGACCTCATCTCATTTGCCTGGCAGATCTCACAGGGGATGCAGTATCTGGCCGAGATGAAGCTCGTTCATCGGG
ACTTGGCAGCCAGAAACATCCTGGTAGCTGAGGGGCGGAAGATGAAGATTTCGGATTTCGGCTTGTCCCGAGATGTTTATGAAGAGGATT
CCTACGTGAAGAGGAGCCAGGGTCGGATTCCAGTTAAATGGATGGCAATTGAATCCCTTTTTGATCATATCTACACCACGCAAAGTGATG
TATGGTCTTTTGGTGTCCTGCTGTGGGAGATCGTGACCCTAGGGGGAAACCCCTATCCTGGGATTCCTCCTGAGCGGCTCTTCAACCTTC
TGAAGACCGGCCACCGGATGGAGAGGCCAGACAACTGCAGCGAGGAGATGTACCGCCTGATGCTGCAATGCTGGAAGCAGGAGCCGGACA
AAAGGCCGGTGTTTGCGGACATCAGCAAAGACCTGGAGAAGATGATGGTTAAGAGGAGAGACTACTTGGACCTTGCGGCGTCCACTCCAT
CTGACTCCCTGATTTATGACGACGGCCTCTCAGAGGAGGAGACACCGCTGGTGGACTGTAATAATGCCCCCCTCCCTCGAGCCCTCCCTT
CCACATGGATTGAAAACAAACTCTATGGTAGAATTTCCCATGCATTTACTAGATTCTAGCACCGCTGTCCCCTTTGCACTATCCTTCCTC
TCTGTGATGCTTTTTAAAAATGTTTCTGGTCTGAACAAAACCAAAGTCTGCTCTGAACCTTTTTATTTGTAAATGTCTGACTTTGCATCC
AGTTTACATTTAGGCATTATTGCAACTATGTTTTTCTAAAAGGATGTGAAAATAAGTGTAATTACCACATTGCCCAGCAACTTAGGATGG
TAGAGGAAAAAACAGATCAGGGCGGAACTCTCAGGGGAGACCAAGAACAGGTTGAATAAGGCGCTTCTGGGGTGGGAATCAAGTCATAGT
ACTTCTACTTTAACTAAGTGGATAAATATACAAATCTGGGGAGGTATTCAGTTGAGAAAGGAGCCACCAGCACCACTCAGCCTGCACTGG
GAGCACAGCCAGGTTCCCCCAGACCCCTCCTGGGCAGGCAGGTGCCTCTCAGAGGCCACCCGGCACTGGCGAGCAGCCACTGGCCAAGCC
TCAGCCCCAGTCCCAGCCACATGTCCTCCATCAGGGGTAGCGAGGTTGCAGGAGCTGGCTGGCCCTGGGAGGACGCACCCCCACTGCTGT
TTTCACATCCTTTCCCTTACCCACCTTCAGGACGGTTGTCACTTATGAAGTCAGTGCTAAAGCTGGAGCAGTTGCTTTTTGAAAGAACAT

>63341_63341_3_PCM1-RET_PCM1_chr8_17851128_ENST00000327578_RET_chr10_43612031_ENST00000340058_length(amino acids)=701AA_BP=341
MASKDKTPKSKSKKRNSTQLKSRVKNIRYESASMSSTCEPCKSRNRHSAQTEEPVQAKVFSRKNHEQLEKIIKCNRSTEISSAHARRILQ
QSNRNACNEAPETGSDFSMFEALRDTIYSEVATLISQNESRPHFLIELFHELQLLNTDYLRQRALYALQDIVSRHISESHEKGENVKSVN
SGTWIASNSELTPSESLATTDDETFEKNFERETHKISEQNDADNASVLSVSSNFEPFATDDLGNTVIHLDQALARMREYERMKTEAESNS
NMRCTCRIIEDGDGAGAGTTVNNLEETPVIENRSSQQPVSEVSTIPCPRIDTQQLDRQIKAIMKEVIPFLKEDPKWEFPRKNLVLGKTLG
EGEFGKVVKATAFHLKGRAGYTTVAVKMLKENASPSELRDLLSEFNVLKQVNHPHVIKLYGACSQDGPLLLIVEYAKYGSLRGFLRESRK
VGPGYLGSGGSRNSSSLDHPDERALTMGDLISFAWQISQGMQYLAEMKLVHRDLAARNILVAEGRKMKISDFGLSRDVYEEDSYVKRSQG
RIPVKWMAIESLFDHIYTTQSDVWSFGVLLWEIVTLGGNPYPGIPPERLFNLLKTGHRMERPDNCSEEMYRLMLQCWKQEPDKRPVFADI

--------------------------------------------------------------
>63341_63341_4_PCM1-RET_PCM1_chr8_17851128_ENST00000327578_RET_chr10_43612031_ENST00000355710_length(transcript)=4337nt_BP=1046nt
GAAAAGCGTCTGCACAGGCCAGCCTGGCATCTAAAGATAAAACTCCCAAGTCAAAAAGTAAGAAGAGGAATTCTACTCAGCTGAAAAGCA
GAGTTAAAAACATCAGGTATGAAAGTGCCAGTATGTCTAGCACATGTGAACCTTGCAAAAGTAGGAACAGACATTCAGCCCAGACTGAAG
AGCCTGTTCAAGCAAAAGTATTCAGCAGAAAGAATCATGAGCAACTGGAAAAAATAATAAAATGTAATAGGTCTACAGAAATATCTTCAG
CACATGCTAGGAGAATACTACAGCAGTCTAACAGAAATGCATGCAATGAAGCGCCAGAAACTGGGAGTGATTTTTCCATGTTTGAAGCTT
TGCGAGATACTATTTATTCTGAAGTAGCTACATTAATTTCTCAAAATGAATCTCGTCCACATTTTCTTATTGAACTCTTCCATGAGCTGC
AGCTACTAAACACAGACTACTTGAGACAGAGGGCTTTATATGCATTGCAGGACATAGTATCCAGACATATTTCTGAGAGCCATGAAAAAG
GAGAAAATGTAAAGTCAGTAAACTCTGGTACTTGGATAGCATCAAACTCAGAACTTACTCCTAGTGAGAGCCTTGCTACTACTGATGATG
AAACTTTTGAGAAGAACTTTGAAAGAGAAACCCATAAAATAAGTGAGCAAAATGATGCTGATAATGCTAGTGTCCTGTCTGTATCATCAA
ATTTTGAGCCTTTTGCAACAGATGATCTAGGTAACACCGTGATTCACTTAGATCAAGCATTAGCCAGAATGAGAGAATATGAGCGTATGA
AGACTGAGGCTGAAAGTAACTCAAATATGAGATGCACCTGCAGGATTATTGAGGATGGAGATGGTGCTGGTGCAGGTACTACAGTTAATA
ATTTAGAAGAAACTCCCGTTATTGAAAATCGTAGTTCACAACAACCTGTAAGTGAAGTTTCTACCATCCCATGTCCTAGAATTGATACTC
AGCAGCTGGACCGGCAAATTAAAGCAATTATGAAAGAAGTCATTCCTTTTTTGAAGGAGGATCCAAAGTGGGAATTCCCTCGGAAGAACT
TGGTTCTTGGAAAAACTCTAGGAGAAGGCGAATTTGGAAAAGTGGTCAAGGCAACGGCCTTCCATCTGAAAGGCAGAGCAGGGTACACCA
CGGTGGCCGTGAAGATGCTGAAAGAGAACGCCTCCCCGAGTGAGCTGCGAGACCTGCTGTCAGAGTTCAACGTCCTGAAGCAGGTCAACC
ACCCACATGTCATCAAATTGTATGGGGCCTGCAGCCAGGATGGCCCGCTCCTCCTCATCGTGGAGTACGCCAAATACGGCTCCCTGCGGG
GCTTCCTCCGCGAGAGCCGCAAAGTGGGGCCTGGCTACCTGGGCAGTGGAGGCAGCCGCAACTCCAGCTCCCTGGACCACCCGGATGAGC
GGGCCCTCACCATGGGCGACCTCATCTCATTTGCCTGGCAGATCTCACAGGGGATGCAGTATCTGGCCGAGATGAAGCTCGTTCATCGGG
ACTTGGCAGCCAGAAACATCCTGGTAGCTGAGGGGCGGAAGATGAAGATTTCGGATTTCGGCTTGTCCCGAGATGTTTATGAAGAGGATT
CCTACGTGAAGAGGAGCCAGGGTCGGATTCCAGTTAAATGGATGGCAATTGAATCCCTTTTTGATCATATCTACACCACGCAAAGTGATG
TATGGTCTTTTGGTGTCCTGCTGTGGGAGATCGTGACCCTAGGGGGAAACCCCTATCCTGGGATTCCTCCTGAGCGGCTCTTCAACCTTC
TGAAGACCGGCCACCGGATGGAGAGGCCAGACAACTGCAGCGAGGAGATGTACCGCCTGATGCTGCAATGCTGGAAGCAGGAGCCGGACA
AAAGGCCGGTGTTTGCGGACATCAGCAAAGACCTGGAGAAGATGATGGTTAAGAGGAGAGACTACTTGGACCTTGCGGCGTCCACTCCAT
CTGACTCCCTGATTTATGACGACGGCCTCTCAGAGGAGGAGACACCGCTGGTGGACTGTAATAATGCCCCCCTCCCTCGAGCCCTCCCTT
CCACATGGATTGAAAACAAACTCTATGGCATGTCAGACCCGAACTGGCCTGGAGAGAGTCCTGTACCACTCACGAGAGCTGATGGCACTA
ACACTGGGTTTCCAAGATATCCAAATGATAGTGTATATGCTAACTGGATGCTTTCACCCTCAGCGGCAAAATTAATGGACACGTTTGATA
GTTAACATTTCTTTGTGAAAGGTAATGGACTCACAAGGGGAAGAAACATGCTGAGAATGGAAAGTCTACCGGCCCTTTCTTTGTGAACGT
CACATTGGCCGAGCCGTGTTCAGTTCCCAGGTGGCAGACTCGTTTTTGGTAGTTTGTTTTAACTTCCAAGGTGGTTTTACTTCTGATAGC
CGGTGATTTTCCCTCCTAGCAGACATGCCACACCGGGTAAGAGCTCTGAGTCTTAGTGGTTAAGCATTCCTTTCTCTTCAGTGCCCAGCA
GCACCCAGTGTTGGTCTGTGTCCATCAGTGACCACCAACATTCTGTGTTCACATGTGTGGGTCCAACACTTACTACCTGGTGTATGAAAT
TGGACCTGAACTGTTGGATTTTTCTAGTTGCCGCCAAACAAGGCAAAAAAATTTAAACATGAAGCACACACACAAAAAAGGCAGTAGGAA
AAATGCTGGCCCTGATGACCTGTCCTTATTCAGAATGAGAGACTGCGGGGGGGGCCTGGGGGTAGTGTCAATGCCCCTCCAGGGCTGGAG
GGGAAGAGGGGCCCCGAGGATGGGCCTGGGCTCAGCATTCGAGATCTTGAGAATGATTTTTTTTAAATCATGCAACCTTTCCTTAGGAAG
ACATTTGGTTTTCATCATGATTAAGATGATTCCTAGATTTAGCACAATGGAGAGATTCCATGCCATCTTTACTATGTGGATGGTGGTATC
AGGGAAGAGGGCTCACAAGACACATTTGTCCCCCGGGCCCACCACATCATCCTCACGTGTTCGGTACTGAGCAGCCACTACCCCTGATGA
GAACAGTATGAAGAAAGGGGGCTGTTGGAGTCCCAGAATTGCTGACAGCAGAGGCTTTGCTGCTGTGAATCCCACCTGCCACCAGCCTGC
AGCACACCCCACAGCCAAGTAGAGGCGAAAGCAGTGGCTCATCCTACCTGTTAGGAGCAGGTAGGGCTTGTACTCACTTTAATTTGAATC
TTATCAACTTACTCATAAAGGGACAGGCTAGCTAGCTGTGTTAGAAGTAGCAATGACAATGACCAAGGACTGCTACACCTCTGATTACAA
TTCTGATGTGAAAAAGATGGTGTTTGGCTCTTATAGAGCCTGTGTGAAAGGCCCATGGATCAGCTCTTCCTGTGTTTGTAATTTAATGCT
GCTACAAGATGTTTCTGTTTCTTAGATTCTGACCATGACTCATAAGCTTCTTGTCATTCTTCATTGCTTGTTTGTGGTCACAGATGCACA
ACACTCCTCCAGTCTTGTGGGGGCAGCTTTTGGGAAGTCTCAGCAGCTCTTCTGGCTGTGTTGTCAGCACTGTAACTTCGCAGAAAAGAG
TCGGATTACCAAAACACTGCCTGCTCTTCAGACTTAAAGCACTGATAGGACTTAAAATAGTCTCATTCAAATACTGTATTTTATATAGGC
ATTTCACAAAAACAGCAAAATTGTGGCATTTTGTGAGGCCAAGGCTTGGATGCGTGTGTAATAGAGCCTTGTGGTGTGTGCGCACACACC
CAGAGGGAGAGTTTGAAAAATGCTTATTGGACACGTAACCTGGCTCTAATTTGGGCTGTTTTTCAGATACACTGTGATAAGTTCTTTTAC
AAATATCTATAGACATGGTAAACTTTTGGTTTTCAGATATGCTTAATGATAGTCTTACTAAATGCAGAAATAAGAATAAACTTTCTCAAA
TTATTAAAAATGCCTACACAGTAAGTGTGAATTGCTGCAACAGGTTTGTTCTCAGGAGGGTAAGAACTCCAGGTCTAAACAGCTGACCCA
GTGATGGGGAATTTATCCTTGACCAATTTATCCTTGACCAATAACCTAATTGTCTATTCCTGAGTTATAAAAGTCCCCATCCTTATTAGC
TCTACTGGAATTTTCATACACGTAAATGCAGAAGTTACTAAGTATTAAGTATTACTGAGTATTAAGTAGTAATCTGTCAGTTATTAAAAT
TTGTAAAATCTATTTATGAAAGGTCATTAAACCAGATCATGTTCCTTTTTTTGTAATCAAGGTGACTAAGAAAATCAGTTGTGTAAATAA

>63341_63341_4_PCM1-RET_PCM1_chr8_17851128_ENST00000327578_RET_chr10_43612031_ENST00000355710_length(amino acids)=743AA_BP=341
MASKDKTPKSKSKKRNSTQLKSRVKNIRYESASMSSTCEPCKSRNRHSAQTEEPVQAKVFSRKNHEQLEKIIKCNRSTEISSAHARRILQ
QSNRNACNEAPETGSDFSMFEALRDTIYSEVATLISQNESRPHFLIELFHELQLLNTDYLRQRALYALQDIVSRHISESHEKGENVKSVN
SGTWIASNSELTPSESLATTDDETFEKNFERETHKISEQNDADNASVLSVSSNFEPFATDDLGNTVIHLDQALARMREYERMKTEAESNS
NMRCTCRIIEDGDGAGAGTTVNNLEETPVIENRSSQQPVSEVSTIPCPRIDTQQLDRQIKAIMKEVIPFLKEDPKWEFPRKNLVLGKTLG
EGEFGKVVKATAFHLKGRAGYTTVAVKMLKENASPSELRDLLSEFNVLKQVNHPHVIKLYGACSQDGPLLLIVEYAKYGSLRGFLRESRK
VGPGYLGSGGSRNSSSLDHPDERALTMGDLISFAWQISQGMQYLAEMKLVHRDLAARNILVAEGRKMKISDFGLSRDVYEEDSYVKRSQG
RIPVKWMAIESLFDHIYTTQSDVWSFGVLLWEIVTLGGNPYPGIPPERLFNLLKTGHRMERPDNCSEEMYRLMLQCWKQEPDKRPVFADI
SKDLEKMMVKRRDYLDLAASTPSDSLIYDDGLSEEETPLVDCNNAPLPRALPSTWIENKLYGMSDPNWPGESPVPLTRADGTNTGFPRYP

--------------------------------------------------------------
>63341_63341_5_PCM1-RET_PCM1_chr8_17851128_ENST00000519253_RET_chr10_43612031_ENST00000340058_length(transcript)=6887nt_BP=5054nt
GCTGCGTAGCTGAGGTCGAAAAGGCGGCCACTGGGGCCGAGGCAGCCAGGAAACGTGTGGGCCTCTCTGCTGCGGTCTCCGAGGGCCGAC
CGCTGCCGGCGGCGGGTCGTGGGGGCTGACTGTCGCTCTGCCTTTGACAGGAGAGGCTGCTTCTTGTAGAGGAAACAGCTTTGAAGTGTG
GAGCGGGAAAGGAGCAGTTTCTGAGCTGCAAAAACTAGTTTCTAAACAGAGAGTTAATTGTTAAATCCAGTATGGCCACAGGAGGAGGTC
CCTTTGAAGATGGCATGAATGATCAGGATTTACCAAACTGGAGTAATGAGAATGTTGATGACAGGCTCAACAATATGGATTGGGGTGCCC
AACAGAAGAAAGCAAATAGATCATCAGAAAAGAATAAGAAAAAGTTTGGTGTAGAAAGTGATAAAAGAGTAACCAATGATATTTCTCCGG
AGTCGTCACCAGGAGTTGGAAGGCGAAGAACAAAGACTCCACATACGTTCCCACACAGTAGATACATGAGTCAGATGTCTGTCCCAGAGC
AGGCAGAATTAGAGAAACTGAAACAGCGGATAAACTTCAGTGATTTAGATCAGAGAAGCATTGGAAGTGATTCCCAAGGTAGAGCAACAG
CTGCTAACAACAAACGTCAGCTTAGTGAAAACCGAAAGCCCTTCAACTTTTTGCCTATGCAGATTAATACTAACAAGAGCAAAGATGCAT
CTACAAACCCCCCAAACAGAGAAACGATTGGATCAGCACAGTGTAAAGAGTTGTTTGCTTCTGCTTTAAGTAATGACCTCTTGCAAAACT
GTCAGGTGTCTGAAGAAGATGGGAGGGGAGAACCTGCAATGGAGAGCAGCCAGATTGTAAGCAGGCTTGTTCAAATTCGCGATTATATTA
CTAAAGCTAGTTCCATGCGGGAAGATCTTGTAGAGAAAAATGAGAGATCTGCTAATGTTGAGCGCCTTACTCATCTAATAGATCACCTTA
AAGAACAAGAGAAGTCATATATGAAATTTCTTAAAAAAATCCTTGCCAGAGATCCTCAGCAGGAGCCTATGGAAGAGATAGAAAATTTGA
AGAAACAACATGATTTATTAAAAAGAATGTTACAACAGCAGGAGCAACTAAGAGCTCTACAGGGACGGCAGGCTGCACTTCTAGCTCTGC
AACATAAAGCAGAGCAAGCTATTGCAGTGATGGATGATTCTGTTGTTGCAGAAACTGCAGGTAGCTTATCTGGCGTCAGTATCACATCTG
AACTAAATGAAGAATTGAATGACTTAATTCAGCGTTTTCATAATCAGCTTCGTGATTCTCAGCCTCCAGCTGTTCCAGACAATAGAAGAC
AGGCAGAAAGTCTTTCATTAACTAGGGAGGTTTCCCAGAGCAGGAAACCATCAGCTTCAGAACGTTTACCTGATGAGAAAGTCGAACTTT
TTAGCAAAATGAGAGTGCTACAGGAAAAGAAACAAAAAATGGACAAATTGCTTGGAGAACTTCATACACTTCGAGATCAGCATCTTAACA
ATTCATCATCCTCTCCACAAAGGAGTGTCGATCAGAGAAGTACTTCAGCTCCCTCTGCTTCTGTAGGCTTGGCACCGGTTGTCAATGGAG
AATCCAATAGCCTCACATCATCTGTTCCTTATCCTACTGCTTCTCTAGTATCTCAGAATGAGAGTGAAAACGAAGGCCACCTCAATCCAT
CTGAAAAACTCCAGAAGTTAAATGAAGTTCGAAAGAGATTGAATGAGCTAAGAGAATTAGTTCATTATTATGAACAAACGTCAGACATGA
TGACAGATGCTGTGAATGAAAACAGGAAAGATGAAGAAACTGAAGAGTCAGAATATGATTCTGAGCATGAAAATTCCGAGCCTGTTACTA
ACATTCGAAATCCACAAGTAGCTTCCACTTGGAATGAAGTAAATAGTCATAGTAATGCACAGTGTGTTTCTAATAATAGAGATGGGCGAA
CAGTTAATTCTAATTGTGAAATTAACAACAGATCTGCTGCCAACATAAGGGCTCTAAACATGCCTCCTTCTTTAGATTGTCGATATAATA
GAGAAGGGGAACAGGAGATTCATGTTGCACAAGGTGAAGATGATGAGGAGGAGGAGGAAGAAGCAGAAGAGGAGGGAGTCAGTGGAGCTT
CATTATCTAGTCACAGGAGCAGTCTGGTTGATGAGCATCCAGAAGATGCTGAATTTGAACAGAAGATCAACCGACTTATGGCTGCAAAAC
AGAAACTTAGACAGTTACAAGATCTTGTTGCTATGGTACAGGATGATGATGCAGCTCAAGGAGTTATCTCTGCCAGTGCATCAAATTTGG
ATGATTTCTACCCAGCAGAAGAAGACACCAAGCAAAATTCAAATAACACTAGAGGAAATGCCAATAAAACACAGAAAGATACTGGAGTAA
ATGAAAAGGCAAGAGAGAAATTTTATGAGGCTAAACTACAGCAGCAACAGAGAGAGCTAAAACAATTGCAGGAAGAAAGAAAGAAACTGA
TTGACATTCAGGAGAAAATTCAAGCATTGCAAACGGCATGCCCTGACTTACAGCTGTCAGCTGCTAGTGTGGGTAACTGTCCCACCAAAA
AATATATGCCAGCTGTTACTTCAACCCCAACTGTTAATCAACACGAGACCAGTACAAGCAAATCTGTTTTTGAGCCTGAAGATTCTTCAA
TAGTAGATAATGAGTTGTGGTCAGAAATGAGAAGACATGAAATGTTGAGGGAGGAGCTGCGACAGAGAAGAAAGCAGCTTGAAGCTCTGA
TGGCTGAACATCAGAGGAGGCAAGGTCTAGCTGAAACTGCATCTCCAGTGGCTGTGTCATTGAGAAGTGATGGATCTGAGAACCTATGTA
CTCCTCAGCAAAGTAGAACAGAAAAAACGATGGCAACTTGGGGAGGGTCTACCCAGTGTGCACTAGATGAAGAAGGAGATGAAGACGGTT
ACCTTTCTGAAGGAATTGTTCGGACAGATGAAGAGGAGGAAGAAGAGCAAGATGCCAGTTCCAATGATAACTTTTCTGTGTGTCCTTCTA
ACAGTGTGAATCATAACTCCTACAATGGAAAGGAAACTAAAAATAGGTGGAAGAACAATTGCCCTTTTTCGGCAGATGAAAATTATCGTC
CTTTAGCCAAGACAAGGCAACAGAATATCAGCATGCAACGGCAAGAAAACCTTCGTTGGGTGTCAGAGCTCTCTTACGTAGAAGAGAAAG
AACAATGGCAAGAACAAATCAATCAGCTAAAGAAACAGCTTGATTTTAGTGTCAGTATTTGTCAGACTTTGATGCAAGACCAGCAGACTC
TATCTTGTCTGCTACAAACTCTTCTCACGGGTCCTTACAGTGTTATGCCCAGCAATGTTGCATCTCCTCAAGTACACTTCATAATGCACC
AGTTGAACCAGTGCTATACTCAGCTAACATGGCAACAGAATAATGTTCAGAGGTTGAAACAAATGCTAAATGAACTTATGCGCCAGCAAA
ATCAGCATCCAGAAAAACCTGGAGGCAAGGAAAGAGGCAGTAGTGCATCGCACCCTCCTTCTCCCAGTTTATTTTGTCCTTTCAGCTTTC
CAACACAGCCTGTAAATCTCTTCAATATACCTGGATTTACTAACTTTTCATCATTTGCACCAGGTATGAATTTCAGCCCTTTATTTCCTT
CTAATTTTGGAGATTTTTCTCAGAATATCTCTACACCCAGTGAACAGCAGCAACCCTTAGCCCAGAATTCTTCAGGAAAAACAGAATATA
TGGCTTTTCCAAAACCTTTTGAAAGCAGTTCCTCTATTGGAGCAGAGAAACCAAGGAATAAAAAACTGCCTGAAGAGGAGGTGGAAAGCA
GTAGGACACCATGGTTATATGAACAAGAAGGTGAAGTAGAGAAACCATTTATCAAGACTGGATTTTCAGTGTCTGTAGAAAAATCTACAA
GTAGTAACCGCAAAAATCAATTAGATACAAACGGAAGAAGACGCCAGTTTGATGAAGAATCACTGGAAAGCTTTAGCAGTATGCCTGATC
CAGTAGATCCAACAACAGTGACTAAAACATTCAAGACAAGAAAAGCGTCTGCACAGGCCAGCCTGGCATCTAAAGATAAAACTCCCAAGT
CAAAAAGTAAGAAGAGGAATTCTACTCAGCTGAAAAGCAGAGTTAAAAACATCAGGTATGAAAGTGCCAGTATGTCTAGCACATGTGAAC
CTTGCAAAAGTAGGAACAGACATTCAGCCCAGACTGAAGAGCCTGTTCAAGCAAAAGTATTCAGCAGAAAGAATCATGAGCAACTGGAAA
AAATAATAAAATGTAATAGGTCTACAGAAATATCTTCAGAAACTGGGAGTGATTTTTCCATGTTTGAAGCTTTGCGAGATACTATTTATT
CTGAAGTAGCTACATTAATTTCTCAAAATGAATCTCGTCCACATTTTCTTATTGAACTCTTCCATGAGCTGCAGCTACTAAACACAGACT
ACTTGAGACAGAGGGCTTTATATGCATTGCAGGACATAGTATCCAGACATATTTCTGAGAGCCATGAAAAAGGAGAAAATGTAAAGTCAG
TAAACTCTGGTACTTGGATAGCATCAAACTCAGAACTTACTCCTAGTGAGAGCCTTGCTACTACTGATGATGAAACTTTTGAGAAGAACT
TTGAAAGAGAAACCCATAAAATAAGTGAGCAAAATGATGCTGATAATGCTAGTGTCCTGTCTGTATCATCAAATTTTGAGCCTTTTGCAA
CAGATGATCTAGGTAACACCGTGATTCACTTAGATCAAGCATTAGCCAGAATGAGAGAATATGAGCGTATGAAGACTGAGGCTGAAAGTA
ACTCAAATATGAGATGCACCTGCAGGATTATTGAGGATGGAGATGGTGCTGGTGCAGAAACTCCCGTTATTGAAAATCGTAGTTCACAAC
AACCTGTAAGTGAAGTTTCTACCATCCCATGTCCTAGAATTGATACTCAGCAGCTGGACCGGCAAATTAAAGCAATTATGAAAGAAGTCA
TTCCTTTTTTGAAGGAGGATCCAAAGTGGGAATTCCCTCGGAAGAACTTGGTTCTTGGAAAAACTCTAGGAGAAGGCGAATTTGGAAAAG
TGGTCAAGGCAACGGCCTTCCATCTGAAAGGCAGAGCAGGGTACACCACGGTGGCCGTGAAGATGCTGAAAGAGAACGCCTCCCCGAGTG
AGCTGCGAGACCTGCTGTCAGAGTTCAACGTCCTGAAGCAGGTCAACCACCCACATGTCATCAAATTGTATGGGGCCTGCAGCCAGGATG
GCCCGCTCCTCCTCATCGTGGAGTACGCCAAATACGGCTCCCTGCGGGGCTTCCTCCGCGAGAGCCGCAAAGTGGGGCCTGGCTACCTGG
GCAGTGGAGGCAGCCGCAACTCCAGCTCCCTGGACCACCCGGATGAGCGGGCCCTCACCATGGGCGACCTCATCTCATTTGCCTGGCAGA
TCTCACAGGGGATGCAGTATCTGGCCGAGATGAAGCTCGTTCATCGGGACTTGGCAGCCAGAAACATCCTGGTAGCTGAGGGGCGGAAGA
TGAAGATTTCGGATTTCGGCTTGTCCCGAGATGTTTATGAAGAGGATTCCTACGTGAAGAGGAGCCAGGGTCGGATTCCAGTTAAATGGA
TGGCAATTGAATCCCTTTTTGATCATATCTACACCACGCAAAGTGATGTATGGTCTTTTGGTGTCCTGCTGTGGGAGATCGTGACCCTAG
GGGGAAACCCCTATCCTGGGATTCCTCCTGAGCGGCTCTTCAACCTTCTGAAGACCGGCCACCGGATGGAGAGGCCAGACAACTGCAGCG
AGGAGATGTACCGCCTGATGCTGCAATGCTGGAAGCAGGAGCCGGACAAAAGGCCGGTGTTTGCGGACATCAGCAAAGACCTGGAGAAGA
TGATGGTTAAGAGGAGAGACTACTTGGACCTTGCGGCGTCCACTCCATCTGACTCCCTGATTTATGACGACGGCCTCTCAGAGGAGGAGA
CACCGCTGGTGGACTGTAATAATGCCCCCCTCCCTCGAGCCCTCCCTTCCACATGGATTGAAAACAAACTCTATGGTAGAATTTCCCATG
CATTTACTAGATTCTAGCACCGCTGTCCCCTTTGCACTATCCTTCCTCTCTGTGATGCTTTTTAAAAATGTTTCTGGTCTGAACAAAACC
AAAGTCTGCTCTGAACCTTTTTATTTGTAAATGTCTGACTTTGCATCCAGTTTACATTTAGGCATTATTGCAACTATGTTTTTCTAAAAG
GATGTGAAAATAAGTGTAATTACCACATTGCCCAGCAACTTAGGATGGTAGAGGAAAAAACAGATCAGGGCGGAACTCTCAGGGGAGACC
AAGAACAGGTTGAATAAGGCGCTTCTGGGGTGGGAATCAAGTCATAGTACTTCTACTTTAACTAAGTGGATAAATATACAAATCTGGGGA
GGTATTCAGTTGAGAAAGGAGCCACCAGCACCACTCAGCCTGCACTGGGAGCACAGCCAGGTTCCCCCAGACCCCTCCTGGGCAGGCAGG
TGCCTCTCAGAGGCCACCCGGCACTGGCGAGCAGCCACTGGCCAAGCCTCAGCCCCAGTCCCAGCCACATGTCCTCCATCAGGGGTAGCG
AGGTTGCAGGAGCTGGCTGGCCCTGGGAGGACGCACCCCCACTGCTGTTTTCACATCCTTTCCCTTACCCACCTTCAGGACGGTTGTCAC
TTATGAAGTCAGTGCTAAAGCTGGAGCAGTTGCTTTTTGAAAGAACATGGTCTGTGGTGCTGTGGTCTTACAATGGACAGTAAATATGGT

>63341_63341_5_PCM1-RET_PCM1_chr8_17851128_ENST00000519253_RET_chr10_43612031_ENST00000340058_length(amino acids)=1961AA_BP=1601
MATGGGPFEDGMNDQDLPNWSNENVDDRLNNMDWGAQQKKANRSSEKNKKKFGVESDKRVTNDISPESSPGVGRRRTKTPHTFPHSRYMS
QMSVPEQAELEKLKQRINFSDLDQRSIGSDSQGRATAANNKRQLSENRKPFNFLPMQINTNKSKDASTNPPNRETIGSAQCKELFASALS
NDLLQNCQVSEEDGRGEPAMESSQIVSRLVQIRDYITKASSMREDLVEKNERSANVERLTHLIDHLKEQEKSYMKFLKKILARDPQQEPM
EEIENLKKQHDLLKRMLQQQEQLRALQGRQAALLALQHKAEQAIAVMDDSVVAETAGSLSGVSITSELNEELNDLIQRFHNQLRDSQPPA
VPDNRRQAESLSLTREVSQSRKPSASERLPDEKVELFSKMRVLQEKKQKMDKLLGELHTLRDQHLNNSSSSPQRSVDQRSTSAPSASVGL
APVVNGESNSLTSSVPYPTASLVSQNESENEGHLNPSEKLQKLNEVRKRLNELRELVHYYEQTSDMMTDAVNENRKDEETEESEYDSEHE
NSEPVTNIRNPQVASTWNEVNSHSNAQCVSNNRDGRTVNSNCEINNRSAANIRALNMPPSLDCRYNREGEQEIHVAQGEDDEEEEEEAEE
EGVSGASLSSHRSSLVDEHPEDAEFEQKINRLMAAKQKLRQLQDLVAMVQDDDAAQGVISASASNLDDFYPAEEDTKQNSNNTRGNANKT
QKDTGVNEKAREKFYEAKLQQQQRELKQLQEERKKLIDIQEKIQALQTACPDLQLSAASVGNCPTKKYMPAVTSTPTVNQHETSTSKSVF
EPEDSSIVDNELWSEMRRHEMLREELRQRRKQLEALMAEHQRRQGLAETASPVAVSLRSDGSENLCTPQQSRTEKTMATWGGSTQCALDE
EGDEDGYLSEGIVRTDEEEEEEQDASSNDNFSVCPSNSVNHNSYNGKETKNRWKNNCPFSADENYRPLAKTRQQNISMQRQENLRWVSEL
SYVEEKEQWQEQINQLKKQLDFSVSICQTLMQDQQTLSCLLQTLLTGPYSVMPSNVASPQVHFIMHQLNQCYTQLTWQQNNVQRLKQMLN
ELMRQQNQHPEKPGGKERGSSASHPPSPSLFCPFSFPTQPVNLFNIPGFTNFSSFAPGMNFSPLFPSNFGDFSQNISTPSEQQQPLAQNS
SGKTEYMAFPKPFESSSSIGAEKPRNKKLPEEEVESSRTPWLYEQEGEVEKPFIKTGFSVSVEKSTSSNRKNQLDTNGRRRQFDEESLES
FSSMPDPVDPTTVTKTFKTRKASAQASLASKDKTPKSKSKKRNSTQLKSRVKNIRYESASMSSTCEPCKSRNRHSAQTEEPVQAKVFSRK
NHEQLEKIIKCNRSTEISSETGSDFSMFEALRDTIYSEVATLISQNESRPHFLIELFHELQLLNTDYLRQRALYALQDIVSRHISESHEK
GENVKSVNSGTWIASNSELTPSESLATTDDETFEKNFERETHKISEQNDADNASVLSVSSNFEPFATDDLGNTVIHLDQALARMREYERM
KTEAESNSNMRCTCRIIEDGDGAGAETPVIENRSSQQPVSEVSTIPCPRIDTQQLDRQIKAIMKEVIPFLKEDPKWEFPRKNLVLGKTLG
EGEFGKVVKATAFHLKGRAGYTTVAVKMLKENASPSELRDLLSEFNVLKQVNHPHVIKLYGACSQDGPLLLIVEYAKYGSLRGFLRESRK
VGPGYLGSGGSRNSSSLDHPDERALTMGDLISFAWQISQGMQYLAEMKLVHRDLAARNILVAEGRKMKISDFGLSRDVYEEDSYVKRSQG
RIPVKWMAIESLFDHIYTTQSDVWSFGVLLWEIVTLGGNPYPGIPPERLFNLLKTGHRMERPDNCSEEMYRLMLQCWKQEPDKRPVFADI

--------------------------------------------------------------
>63341_63341_6_PCM1-RET_PCM1_chr8_17851128_ENST00000519253_RET_chr10_43612031_ENST00000355710_length(transcript)=8345nt_BP=5054nt
GCTGCGTAGCTGAGGTCGAAAAGGCGGCCACTGGGGCCGAGGCAGCCAGGAAACGTGTGGGCCTCTCTGCTGCGGTCTCCGAGGGCCGAC
CGCTGCCGGCGGCGGGTCGTGGGGGCTGACTGTCGCTCTGCCTTTGACAGGAGAGGCTGCTTCTTGTAGAGGAAACAGCTTTGAAGTGTG
GAGCGGGAAAGGAGCAGTTTCTGAGCTGCAAAAACTAGTTTCTAAACAGAGAGTTAATTGTTAAATCCAGTATGGCCACAGGAGGAGGTC
CCTTTGAAGATGGCATGAATGATCAGGATTTACCAAACTGGAGTAATGAGAATGTTGATGACAGGCTCAACAATATGGATTGGGGTGCCC
AACAGAAGAAAGCAAATAGATCATCAGAAAAGAATAAGAAAAAGTTTGGTGTAGAAAGTGATAAAAGAGTAACCAATGATATTTCTCCGG
AGTCGTCACCAGGAGTTGGAAGGCGAAGAACAAAGACTCCACATACGTTCCCACACAGTAGATACATGAGTCAGATGTCTGTCCCAGAGC
AGGCAGAATTAGAGAAACTGAAACAGCGGATAAACTTCAGTGATTTAGATCAGAGAAGCATTGGAAGTGATTCCCAAGGTAGAGCAACAG
CTGCTAACAACAAACGTCAGCTTAGTGAAAACCGAAAGCCCTTCAACTTTTTGCCTATGCAGATTAATACTAACAAGAGCAAAGATGCAT
CTACAAACCCCCCAAACAGAGAAACGATTGGATCAGCACAGTGTAAAGAGTTGTTTGCTTCTGCTTTAAGTAATGACCTCTTGCAAAACT
GTCAGGTGTCTGAAGAAGATGGGAGGGGAGAACCTGCAATGGAGAGCAGCCAGATTGTAAGCAGGCTTGTTCAAATTCGCGATTATATTA
CTAAAGCTAGTTCCATGCGGGAAGATCTTGTAGAGAAAAATGAGAGATCTGCTAATGTTGAGCGCCTTACTCATCTAATAGATCACCTTA
AAGAACAAGAGAAGTCATATATGAAATTTCTTAAAAAAATCCTTGCCAGAGATCCTCAGCAGGAGCCTATGGAAGAGATAGAAAATTTGA
AGAAACAACATGATTTATTAAAAAGAATGTTACAACAGCAGGAGCAACTAAGAGCTCTACAGGGACGGCAGGCTGCACTTCTAGCTCTGC
AACATAAAGCAGAGCAAGCTATTGCAGTGATGGATGATTCTGTTGTTGCAGAAACTGCAGGTAGCTTATCTGGCGTCAGTATCACATCTG
AACTAAATGAAGAATTGAATGACTTAATTCAGCGTTTTCATAATCAGCTTCGTGATTCTCAGCCTCCAGCTGTTCCAGACAATAGAAGAC
AGGCAGAAAGTCTTTCATTAACTAGGGAGGTTTCCCAGAGCAGGAAACCATCAGCTTCAGAACGTTTACCTGATGAGAAAGTCGAACTTT
TTAGCAAAATGAGAGTGCTACAGGAAAAGAAACAAAAAATGGACAAATTGCTTGGAGAACTTCATACACTTCGAGATCAGCATCTTAACA
ATTCATCATCCTCTCCACAAAGGAGTGTCGATCAGAGAAGTACTTCAGCTCCCTCTGCTTCTGTAGGCTTGGCACCGGTTGTCAATGGAG
AATCCAATAGCCTCACATCATCTGTTCCTTATCCTACTGCTTCTCTAGTATCTCAGAATGAGAGTGAAAACGAAGGCCACCTCAATCCAT
CTGAAAAACTCCAGAAGTTAAATGAAGTTCGAAAGAGATTGAATGAGCTAAGAGAATTAGTTCATTATTATGAACAAACGTCAGACATGA
TGACAGATGCTGTGAATGAAAACAGGAAAGATGAAGAAACTGAAGAGTCAGAATATGATTCTGAGCATGAAAATTCCGAGCCTGTTACTA
ACATTCGAAATCCACAAGTAGCTTCCACTTGGAATGAAGTAAATAGTCATAGTAATGCACAGTGTGTTTCTAATAATAGAGATGGGCGAA
CAGTTAATTCTAATTGTGAAATTAACAACAGATCTGCTGCCAACATAAGGGCTCTAAACATGCCTCCTTCTTTAGATTGTCGATATAATA
GAGAAGGGGAACAGGAGATTCATGTTGCACAAGGTGAAGATGATGAGGAGGAGGAGGAAGAAGCAGAAGAGGAGGGAGTCAGTGGAGCTT
CATTATCTAGTCACAGGAGCAGTCTGGTTGATGAGCATCCAGAAGATGCTGAATTTGAACAGAAGATCAACCGACTTATGGCTGCAAAAC
AGAAACTTAGACAGTTACAAGATCTTGTTGCTATGGTACAGGATGATGATGCAGCTCAAGGAGTTATCTCTGCCAGTGCATCAAATTTGG
ATGATTTCTACCCAGCAGAAGAAGACACCAAGCAAAATTCAAATAACACTAGAGGAAATGCCAATAAAACACAGAAAGATACTGGAGTAA
ATGAAAAGGCAAGAGAGAAATTTTATGAGGCTAAACTACAGCAGCAACAGAGAGAGCTAAAACAATTGCAGGAAGAAAGAAAGAAACTGA
TTGACATTCAGGAGAAAATTCAAGCATTGCAAACGGCATGCCCTGACTTACAGCTGTCAGCTGCTAGTGTGGGTAACTGTCCCACCAAAA
AATATATGCCAGCTGTTACTTCAACCCCAACTGTTAATCAACACGAGACCAGTACAAGCAAATCTGTTTTTGAGCCTGAAGATTCTTCAA
TAGTAGATAATGAGTTGTGGTCAGAAATGAGAAGACATGAAATGTTGAGGGAGGAGCTGCGACAGAGAAGAAAGCAGCTTGAAGCTCTGA
TGGCTGAACATCAGAGGAGGCAAGGTCTAGCTGAAACTGCATCTCCAGTGGCTGTGTCATTGAGAAGTGATGGATCTGAGAACCTATGTA
CTCCTCAGCAAAGTAGAACAGAAAAAACGATGGCAACTTGGGGAGGGTCTACCCAGTGTGCACTAGATGAAGAAGGAGATGAAGACGGTT
ACCTTTCTGAAGGAATTGTTCGGACAGATGAAGAGGAGGAAGAAGAGCAAGATGCCAGTTCCAATGATAACTTTTCTGTGTGTCCTTCTA
ACAGTGTGAATCATAACTCCTACAATGGAAAGGAAACTAAAAATAGGTGGAAGAACAATTGCCCTTTTTCGGCAGATGAAAATTATCGTC
CTTTAGCCAAGACAAGGCAACAGAATATCAGCATGCAACGGCAAGAAAACCTTCGTTGGGTGTCAGAGCTCTCTTACGTAGAAGAGAAAG
AACAATGGCAAGAACAAATCAATCAGCTAAAGAAACAGCTTGATTTTAGTGTCAGTATTTGTCAGACTTTGATGCAAGACCAGCAGACTC
TATCTTGTCTGCTACAAACTCTTCTCACGGGTCCTTACAGTGTTATGCCCAGCAATGTTGCATCTCCTCAAGTACACTTCATAATGCACC
AGTTGAACCAGTGCTATACTCAGCTAACATGGCAACAGAATAATGTTCAGAGGTTGAAACAAATGCTAAATGAACTTATGCGCCAGCAAA
ATCAGCATCCAGAAAAACCTGGAGGCAAGGAAAGAGGCAGTAGTGCATCGCACCCTCCTTCTCCCAGTTTATTTTGTCCTTTCAGCTTTC
CAACACAGCCTGTAAATCTCTTCAATATACCTGGATTTACTAACTTTTCATCATTTGCACCAGGTATGAATTTCAGCCCTTTATTTCCTT
CTAATTTTGGAGATTTTTCTCAGAATATCTCTACACCCAGTGAACAGCAGCAACCCTTAGCCCAGAATTCTTCAGGAAAAACAGAATATA
TGGCTTTTCCAAAACCTTTTGAAAGCAGTTCCTCTATTGGAGCAGAGAAACCAAGGAATAAAAAACTGCCTGAAGAGGAGGTGGAAAGCA
GTAGGACACCATGGTTATATGAACAAGAAGGTGAAGTAGAGAAACCATTTATCAAGACTGGATTTTCAGTGTCTGTAGAAAAATCTACAA
GTAGTAACCGCAAAAATCAATTAGATACAAACGGAAGAAGACGCCAGTTTGATGAAGAATCACTGGAAAGCTTTAGCAGTATGCCTGATC
CAGTAGATCCAACAACAGTGACTAAAACATTCAAGACAAGAAAAGCGTCTGCACAGGCCAGCCTGGCATCTAAAGATAAAACTCCCAAGT
CAAAAAGTAAGAAGAGGAATTCTACTCAGCTGAAAAGCAGAGTTAAAAACATCAGGTATGAAAGTGCCAGTATGTCTAGCACATGTGAAC
CTTGCAAAAGTAGGAACAGACATTCAGCCCAGACTGAAGAGCCTGTTCAAGCAAAAGTATTCAGCAGAAAGAATCATGAGCAACTGGAAA
AAATAATAAAATGTAATAGGTCTACAGAAATATCTTCAGAAACTGGGAGTGATTTTTCCATGTTTGAAGCTTTGCGAGATACTATTTATT
CTGAAGTAGCTACATTAATTTCTCAAAATGAATCTCGTCCACATTTTCTTATTGAACTCTTCCATGAGCTGCAGCTACTAAACACAGACT
ACTTGAGACAGAGGGCTTTATATGCATTGCAGGACATAGTATCCAGACATATTTCTGAGAGCCATGAAAAAGGAGAAAATGTAAAGTCAG
TAAACTCTGGTACTTGGATAGCATCAAACTCAGAACTTACTCCTAGTGAGAGCCTTGCTACTACTGATGATGAAACTTTTGAGAAGAACT
TTGAAAGAGAAACCCATAAAATAAGTGAGCAAAATGATGCTGATAATGCTAGTGTCCTGTCTGTATCATCAAATTTTGAGCCTTTTGCAA
CAGATGATCTAGGTAACACCGTGATTCACTTAGATCAAGCATTAGCCAGAATGAGAGAATATGAGCGTATGAAGACTGAGGCTGAAAGTA
ACTCAAATATGAGATGCACCTGCAGGATTATTGAGGATGGAGATGGTGCTGGTGCAGAAACTCCCGTTATTGAAAATCGTAGTTCACAAC
AACCTGTAAGTGAAGTTTCTACCATCCCATGTCCTAGAATTGATACTCAGCAGCTGGACCGGCAAATTAAAGCAATTATGAAAGAAGTCA
TTCCTTTTTTGAAGGAGGATCCAAAGTGGGAATTCCCTCGGAAGAACTTGGTTCTTGGAAAAACTCTAGGAGAAGGCGAATTTGGAAAAG
TGGTCAAGGCAACGGCCTTCCATCTGAAAGGCAGAGCAGGGTACACCACGGTGGCCGTGAAGATGCTGAAAGAGAACGCCTCCCCGAGTG
AGCTGCGAGACCTGCTGTCAGAGTTCAACGTCCTGAAGCAGGTCAACCACCCACATGTCATCAAATTGTATGGGGCCTGCAGCCAGGATG
GCCCGCTCCTCCTCATCGTGGAGTACGCCAAATACGGCTCCCTGCGGGGCTTCCTCCGCGAGAGCCGCAAAGTGGGGCCTGGCTACCTGG
GCAGTGGAGGCAGCCGCAACTCCAGCTCCCTGGACCACCCGGATGAGCGGGCCCTCACCATGGGCGACCTCATCTCATTTGCCTGGCAGA
TCTCACAGGGGATGCAGTATCTGGCCGAGATGAAGCTCGTTCATCGGGACTTGGCAGCCAGAAACATCCTGGTAGCTGAGGGGCGGAAGA
TGAAGATTTCGGATTTCGGCTTGTCCCGAGATGTTTATGAAGAGGATTCCTACGTGAAGAGGAGCCAGGGTCGGATTCCAGTTAAATGGA
TGGCAATTGAATCCCTTTTTGATCATATCTACACCACGCAAAGTGATGTATGGTCTTTTGGTGTCCTGCTGTGGGAGATCGTGACCCTAG
GGGGAAACCCCTATCCTGGGATTCCTCCTGAGCGGCTCTTCAACCTTCTGAAGACCGGCCACCGGATGGAGAGGCCAGACAACTGCAGCG
AGGAGATGTACCGCCTGATGCTGCAATGCTGGAAGCAGGAGCCGGACAAAAGGCCGGTGTTTGCGGACATCAGCAAAGACCTGGAGAAGA
TGATGGTTAAGAGGAGAGACTACTTGGACCTTGCGGCGTCCACTCCATCTGACTCCCTGATTTATGACGACGGCCTCTCAGAGGAGGAGA
CACCGCTGGTGGACTGTAATAATGCCCCCCTCCCTCGAGCCCTCCCTTCCACATGGATTGAAAACAAACTCTATGGCATGTCAGACCCGA
ACTGGCCTGGAGAGAGTCCTGTACCACTCACGAGAGCTGATGGCACTAACACTGGGTTTCCAAGATATCCAAATGATAGTGTATATGCTA
ACTGGATGCTTTCACCCTCAGCGGCAAAATTAATGGACACGTTTGATAGTTAACATTTCTTTGTGAAAGGTAATGGACTCACAAGGGGAA
GAAACATGCTGAGAATGGAAAGTCTACCGGCCCTTTCTTTGTGAACGTCACATTGGCCGAGCCGTGTTCAGTTCCCAGGTGGCAGACTCG
TTTTTGGTAGTTTGTTTTAACTTCCAAGGTGGTTTTACTTCTGATAGCCGGTGATTTTCCCTCCTAGCAGACATGCCACACCGGGTAAGA
GCTCTGAGTCTTAGTGGTTAAGCATTCCTTTCTCTTCAGTGCCCAGCAGCACCCAGTGTTGGTCTGTGTCCATCAGTGACCACCAACATT
CTGTGTTCACATGTGTGGGTCCAACACTTACTACCTGGTGTATGAAATTGGACCTGAACTGTTGGATTTTTCTAGTTGCCGCCAAACAAG
GCAAAAAAATTTAAACATGAAGCACACACACAAAAAAGGCAGTAGGAAAAATGCTGGCCCTGATGACCTGTCCTTATTCAGAATGAGAGA
CTGCGGGGGGGGCCTGGGGGTAGTGTCAATGCCCCTCCAGGGCTGGAGGGGAAGAGGGGCCCCGAGGATGGGCCTGGGCTCAGCATTCGA
GATCTTGAGAATGATTTTTTTTAAATCATGCAACCTTTCCTTAGGAAGACATTTGGTTTTCATCATGATTAAGATGATTCCTAGATTTAG
CACAATGGAGAGATTCCATGCCATCTTTACTATGTGGATGGTGGTATCAGGGAAGAGGGCTCACAAGACACATTTGTCCCCCGGGCCCAC
CACATCATCCTCACGTGTTCGGTACTGAGCAGCCACTACCCCTGATGAGAACAGTATGAAGAAAGGGGGCTGTTGGAGTCCCAGAATTGC
TGACAGCAGAGGCTTTGCTGCTGTGAATCCCACCTGCCACCAGCCTGCAGCACACCCCACAGCCAAGTAGAGGCGAAAGCAGTGGCTCAT
CCTACCTGTTAGGAGCAGGTAGGGCTTGTACTCACTTTAATTTGAATCTTATCAACTTACTCATAAAGGGACAGGCTAGCTAGCTGTGTT
AGAAGTAGCAATGACAATGACCAAGGACTGCTACACCTCTGATTACAATTCTGATGTGAAAAAGATGGTGTTTGGCTCTTATAGAGCCTG
TGTGAAAGGCCCATGGATCAGCTCTTCCTGTGTTTGTAATTTAATGCTGCTACAAGATGTTTCTGTTTCTTAGATTCTGACCATGACTCA
TAAGCTTCTTGTCATTCTTCATTGCTTGTTTGTGGTCACAGATGCACAACACTCCTCCAGTCTTGTGGGGGCAGCTTTTGGGAAGTCTCA
GCAGCTCTTCTGGCTGTGTTGTCAGCACTGTAACTTCGCAGAAAAGAGTCGGATTACCAAAACACTGCCTGCTCTTCAGACTTAAAGCAC
TGATAGGACTTAAAATAGTCTCATTCAAATACTGTATTTTATATAGGCATTTCACAAAAACAGCAAAATTGTGGCATTTTGTGAGGCCAA
GGCTTGGATGCGTGTGTAATAGAGCCTTGTGGTGTGTGCGCACACACCCAGAGGGAGAGTTTGAAAAATGCTTATTGGACACGTAACCTG
GCTCTAATTTGGGCTGTTTTTCAGATACACTGTGATAAGTTCTTTTACAAATATCTATAGACATGGTAAACTTTTGGTTTTCAGATATGC
TTAATGATAGTCTTACTAAATGCAGAAATAAGAATAAACTTTCTCAAATTATTAAAAATGCCTACACAGTAAGTGTGAATTGCTGCAACA
GGTTTGTTCTCAGGAGGGTAAGAACTCCAGGTCTAAACAGCTGACCCAGTGATGGGGAATTTATCCTTGACCAATTTATCCTTGACCAAT
AACCTAATTGTCTATTCCTGAGTTATAAAAGTCCCCATCCTTATTAGCTCTACTGGAATTTTCATACACGTAAATGCAGAAGTTACTAAG
TATTAAGTATTACTGAGTATTAAGTAGTAATCTGTCAGTTATTAAAATTTGTAAAATCTATTTATGAAAGGTCATTAAACCAGATCATGT

>63341_63341_6_PCM1-RET_PCM1_chr8_17851128_ENST00000519253_RET_chr10_43612031_ENST00000355710_length(amino acids)=2003AA_BP=1601
MATGGGPFEDGMNDQDLPNWSNENVDDRLNNMDWGAQQKKANRSSEKNKKKFGVESDKRVTNDISPESSPGVGRRRTKTPHTFPHSRYMS
QMSVPEQAELEKLKQRINFSDLDQRSIGSDSQGRATAANNKRQLSENRKPFNFLPMQINTNKSKDASTNPPNRETIGSAQCKELFASALS
NDLLQNCQVSEEDGRGEPAMESSQIVSRLVQIRDYITKASSMREDLVEKNERSANVERLTHLIDHLKEQEKSYMKFLKKILARDPQQEPM
EEIENLKKQHDLLKRMLQQQEQLRALQGRQAALLALQHKAEQAIAVMDDSVVAETAGSLSGVSITSELNEELNDLIQRFHNQLRDSQPPA
VPDNRRQAESLSLTREVSQSRKPSASERLPDEKVELFSKMRVLQEKKQKMDKLLGELHTLRDQHLNNSSSSPQRSVDQRSTSAPSASVGL
APVVNGESNSLTSSVPYPTASLVSQNESENEGHLNPSEKLQKLNEVRKRLNELRELVHYYEQTSDMMTDAVNENRKDEETEESEYDSEHE
NSEPVTNIRNPQVASTWNEVNSHSNAQCVSNNRDGRTVNSNCEINNRSAANIRALNMPPSLDCRYNREGEQEIHVAQGEDDEEEEEEAEE
EGVSGASLSSHRSSLVDEHPEDAEFEQKINRLMAAKQKLRQLQDLVAMVQDDDAAQGVISASASNLDDFYPAEEDTKQNSNNTRGNANKT
QKDTGVNEKAREKFYEAKLQQQQRELKQLQEERKKLIDIQEKIQALQTACPDLQLSAASVGNCPTKKYMPAVTSTPTVNQHETSTSKSVF
EPEDSSIVDNELWSEMRRHEMLREELRQRRKQLEALMAEHQRRQGLAETASPVAVSLRSDGSENLCTPQQSRTEKTMATWGGSTQCALDE
EGDEDGYLSEGIVRTDEEEEEEQDASSNDNFSVCPSNSVNHNSYNGKETKNRWKNNCPFSADENYRPLAKTRQQNISMQRQENLRWVSEL
SYVEEKEQWQEQINQLKKQLDFSVSICQTLMQDQQTLSCLLQTLLTGPYSVMPSNVASPQVHFIMHQLNQCYTQLTWQQNNVQRLKQMLN
ELMRQQNQHPEKPGGKERGSSASHPPSPSLFCPFSFPTQPVNLFNIPGFTNFSSFAPGMNFSPLFPSNFGDFSQNISTPSEQQQPLAQNS
SGKTEYMAFPKPFESSSSIGAEKPRNKKLPEEEVESSRTPWLYEQEGEVEKPFIKTGFSVSVEKSTSSNRKNQLDTNGRRRQFDEESLES
FSSMPDPVDPTTVTKTFKTRKASAQASLASKDKTPKSKSKKRNSTQLKSRVKNIRYESASMSSTCEPCKSRNRHSAQTEEPVQAKVFSRK
NHEQLEKIIKCNRSTEISSETGSDFSMFEALRDTIYSEVATLISQNESRPHFLIELFHELQLLNTDYLRQRALYALQDIVSRHISESHEK
GENVKSVNSGTWIASNSELTPSESLATTDDETFEKNFERETHKISEQNDADNASVLSVSSNFEPFATDDLGNTVIHLDQALARMREYERM
KTEAESNSNMRCTCRIIEDGDGAGAETPVIENRSSQQPVSEVSTIPCPRIDTQQLDRQIKAIMKEVIPFLKEDPKWEFPRKNLVLGKTLG
EGEFGKVVKATAFHLKGRAGYTTVAVKMLKENASPSELRDLLSEFNVLKQVNHPHVIKLYGACSQDGPLLLIVEYAKYGSLRGFLRESRK
VGPGYLGSGGSRNSSSLDHPDERALTMGDLISFAWQISQGMQYLAEMKLVHRDLAARNILVAEGRKMKISDFGLSRDVYEEDSYVKRSQG
RIPVKWMAIESLFDHIYTTQSDVWSFGVLLWEIVTLGGNPYPGIPPERLFNLLKTGHRMERPDNCSEEMYRLMLQCWKQEPDKRPVFADI
SKDLEKMMVKRRDYLDLAASTPSDSLIYDDGLSEEETPLVDCNNAPLPRALPSTWIENKLYGMSDPNWPGESPVPLTRADGTNTGFPRYP

--------------------------------------------------------------
>63341_63341_7_PCM1-RET_PCM1_chr8_17851128_ENST00000524226_RET_chr10_43612031_ENST00000340058_length(transcript)=6557nt_BP=4724nt
AGCAGTTTCTGAGCTGCAAAAACTAGTTTCTAAACAGAGAGTTAATTGTTAAATCCAGTATGGCCACAGGAGGAGGTCCCTTTGAAGATG
GCATGAATGATCAGGATTTACCAAACTGGAGTAATGAGAATGTTGATGACAGGCTCAACAATATGGATTGGGGTGCCCAACAGAAGAAAG
CAAATAGATCATCAGAAAAGAATAAGAAAAAGTTTGGTGTAGAAAGTGATAAAAGAGTAACCAATGATATTTCTCCGGAGTCGTCACCAG
GAGTTGGAAGGCGAAGAACAAAGACTCCACATACGTTCCCACACAGTAGATACATGAGTCAGATGTCTGTCCCAGAGCAGGCAGAATTAG
AGAAACTGAAACAGCGGATAAACTTCAGTGATTTAGATCAGAGAAGCATTGGAAGTGATTCCCAAGGTAGAGCAACAGCTGCTAACAACA
AACGTCAGCTTAGTGAAAACCGAAAGCCCTTCAACTTTTTGCCTATGCAGATTAATACTAACAAGAGCAAAGATGCATCTACAAACCCCC
CAAACAGAGAAACGATTGGATCAGCACAGTGTAAAGAGTTGTTTGCTTCTGCTTTAAGTAATGACCTCTTGCAAAACTGTCAGGTGTCTG
AAGAAGATGGGAGGGGAGAACCTGCAATGGAGAGCAGCCAGATTGTAAGCAGGCTTGTTCAAATTCGCGATTATATTACTAAAGCTAGTT
CCATGCGGGAAGATCTTGTAGAGAAAAATGAGAGATCTGCTAATGTTGAGCGCCTTACTCATCTAATAGATCACCTTAAAGAACAAGAGA
AGTCATATATGAAATTTCTTAAAAAAATCCTTGCCAGAGATCCTCAGCAGGAGCCTATGGAAGAGATAGAAAATTTGAAGAAACAACATG
ATTTATTAAAAAGAATGTTACAACAGCAGGAGCAACTAAGAGCTCTACAGGGACGGCAGGCTGCACTTCTAGCTCTGCAACATAAAGCAG
AGCAAGCTATTGCAGTGATGGATGATTCTGTTGTTGCAGAAACTGCAGGTAGCTTATCTGGCGTCAGTATCACATCTGAACTAAATGAAG
AATTGAATGACTTAATTCAGCGTTTTCATAATCAGCTTCGTGATTCTCAGCCTCCAGCTGTTCCAGACAATAGAAGACAGGCAGAAAGTC
TTTCATTAACTAGGGAGGTTTCCCAGAGCAGGAAACCATCAGCTTCAGAACGTTTACCTGATGAGAAAGTCGAACTTTTTAGCAAAATGA
GAGTGCTACAGGAAAAGAAACAAAAAATGGACAAATTGCTTGGAGAACTTCATACACTTCGAGATCAGCATCTTAACAATTCATCATCCT
CTCCACAAAGGAGTGTCGATCAGAGAAGTACTTCAGCTCCCTCTGCTTCTGTAGGCTTGGCACCGGTTGTCAATGGAGAATCCAATAGCC
TCACATCATCTGTTCCTTATCCTACTGCTTCTCTAGTATCTCAGAATGAGAGTGAAAACGAAGGCCACCTCAATCCATCTGAAAAACTCC
AGAAGTTAAATGAAGTTCGAAAGAGATTGAATGAGCTAAGAGAATTAGTTCATTATTATGAACAAACGTCAGACATGATGACAGATGCTG
TGAATGAAAACAGGAAAGATGAAGAAACTGAAGAGTCAGAATATGATTCTGAGCATGAAAATTCCGAGCCTGTTACTAACATTCGAAATC
CACAAGTAGCTTCCACTTGGAATGAAGTAAATAGTCATAGTAATGCACAGTGTGTTTCTAATAATAGAGATGGGCGAACAGTTAATTCTA
ATTGTGAAATTAACAACAGATCTGCTGCCAACATAAGGGCTCTAAACATGCCTCCTTCTTTAGCAGATTGTCGATATAATAGAGAAGGGG
AACAGGAGATTCATGTTGCACAAGGTGAAGATGATGAGGAGGAGGAGGAAGAAGCAGAAGAGGAGGGAGTCAGTGGAGCTTCATTATCTA
GTCACAGGAGCAGTCTGGTTGATGAGCATCCAGAAGATGCTGAATTTGAACAGAAGATCAACCGACTTATGGCTGCAAAACAGAAACTTA
GACAGTTACAAGATCTTGTTGCTATGGTACAGGATGATGATGCAGCTCAAGGAGTTATCTCTGCCAGTGCATCAAATTTGGATGATTTCT
ACCCAGCAGAAGAAGACACCAAGCAAAATTCAAATAACACTAGAGGAAATGCCAATAAAACACAGAAAGATACTGGAGTAAATGAAAAGG
CAAGAGAGAAATTTTATGAGGCTAAACTACAGCAGCAACAGAGAGAGCTAAAACAATTGCAGGAAGAAAGAAAGAAACTGATTGACATTC
AGGAGAAAATTCAAGCATTGCAAACGGCATGCCCTGACTTACAGCTGTCAGCTGCTAGTGTGGGTAACTGTCCCACCAAAAAATATATGC
CAGCTGTTACTTCAACCCCAACTGTTAATCAACACGAGACCAGTACAAGCAAATCTGTTTTTGAGCCTGAAGATTCTTCAATAGTAGATA
ATGAGTTGTGGTCAGAAATGAGAAGACATGAAATGTTGAGGGAGGAGCTGCGACAGAGAAGAAAGCAGCTTGAAGCTCTGATGGCTGAAC
ATCAGAGGAGGCAAGGTCTAGCTGAAACTGCATCTCCAGTGGCTGTGTCATTGAGAAGTGATGGATCTGAGAACCTATGTACTCCTCAGC
AAAGTAGAACAGAAAAAACGATGGCAACTTGGGGAGGGTCTACCCAGTGTGCACTAGATGAAGAAGGAGATGAAGACGGTTACCTTTCTG
AAGGAATTGTTCGGACAGATGAAGAGGAGGAAGAAGAGCAAGATGCCAGTTCCAATGATAACTTTTCTGTGTGTCCTTCTAACAGTGTGA
ATCATAACTCCTACAATGGAAAGGAAACTAAAAATAGGTGGAAGAACAATTGCCCTTTTTCGGCAGATGAAAATTATCGTCCTTTAGCCA
AGACAAGGCAACAGAATATCAGCATGCAACGGCAAGAAAACCTTCGTTGGGTGTCAGAGCTCTCTTACGTAGAAGAGAAAGAACAATGGC
AAGAACAAATCAATCAGCTAAAGAAACAGCTTGATTTTAGTGTCAGTATTTGTCAGACTTTGATGCAAGACCAGCAGACTCTATCTTGTC
TGCTACAAACTCTTCTCACGGGTCCTTACAGTGTTATGCCCAGCAATGTTGCATCTCCTCAAGTACACTTCATAATGCACCAGTTGAACC
AGTGCTATACTCAGCTAACATGGCAACAGAATAATGTTCAGAGGTTGAAACAAATGCTAAATGAACTTATGCGCCAGCAAAATCAGCATC
CAGAAAAACCTGGAGGCAAGGAAAGAGGCAGTAGTGCATCGCACCCTCCTTCTCCCAGTTTATTTTGTCCTTTCAGCTTTCCAACACAGC
CTGTAAATCTCTTCAATATACCTGGATTTACTAACTTTTCATCATTTGCACCAGGTATGAATTTCAGCCCTTTATTTCCTTCTAATTTTG
GAGATTTTTCTCAGAATATCTCTACACCCAGTGAACAGCAGCAACCCTTAGCCCAGAATTCTTCAGGAAAAACAGAATATATGGCTTTTC
CAAAACCTTTTGAAAGCAGTTCCTCTATTGGAGCAGAGAAACCAAGGAATAAAAAACTGCCTGAAGAGGAGGTGGAAAGCAGTAGGACAC
CATGGTTATATGAACAAGAAGGTGAAGTAGAGAAACCATTTATCAAGACTGGATTTTCAGTGTCTGTAGAAAAATCTACAAGTAGTAACC
GCAAAAATCAATTAGATACAAACGGAAGAAGACGCCAGTTTGATGAAGAATCACTGGAAAGCTTTAGCAGTATGCCTGATCCAGTAGATC
CAACAACAGTGACTAAAACATTCAAGACAAGAAAAGCGTCTGCACAGGCCAGCCTGGCATCTAAAGATAAAACTCCCAAGTCAAAAAGTA
AGAAGAGGAATTCTACTCAGCTGAAAAGCAGAGTTAAAAACATCAAAACTGGGAGTGATTTTTCCATGTTTGAAGCTTTGCGAGATACTA
TTTATTCTGAAGTAGCTACATTAATTTCTCAAAATGAATCTCGTCCACATTTTCTTATTGAACTCTTCCATGAGCTGCAGCTACTAAACA
CAGACTACTTGAGACAGAGGGCTTTATATGCATTGCAGGACATAGTATCCAGACATATTTCTGAGAGCCATGAAAAAGGAGAAAATGTAA
AGTCAGTAAACTCTGGTACTTGGATAGCATCAAACTCAGAACTTACTCCTAGTGAGAGCCTTGCTACTACTGATGATGAAACTTTTGAGA
AGAACTTTGAAAGAGAAACCCATAAAATAAGTGAGCAAAATGATGCTGATAATGCTAGTGTCCTGTCTGTATCATCAAATTTTGAGCCTT
TTGCAACAGATGATCTAGGTAACACCGTGATTCACTTAGATCAAGCATTAGCCAGAATGAGAGAATATGAGCGTATGAAGACTGAGGCTG
AAAGTAACTCAAATATGAGATGCACCTGCAGGATTATTGAGGATGGAGATGGTGCTGGTGCAGGTACTACAGTTAATAATTTAGAAGAAA
CTCCCGTTATTGAAAATCGTAGTTCACAACAACCTGTAAGTGAAGTTTCTACCATCCCATGTCCTAGAATTGATACTCAGCAGCTGGACC
GGCAAATTAAAGCAATTATGAAAGAAGTCATTCCTTTTTTGAAGGAGGATCCAAAGTGGGAATTCCCTCGGAAGAACTTGGTTCTTGGAA
AAACTCTAGGAGAAGGCGAATTTGGAAAAGTGGTCAAGGCAACGGCCTTCCATCTGAAAGGCAGAGCAGGGTACACCACGGTGGCCGTGA
AGATGCTGAAAGAGAACGCCTCCCCGAGTGAGCTGCGAGACCTGCTGTCAGAGTTCAACGTCCTGAAGCAGGTCAACCACCCACATGTCA
TCAAATTGTATGGGGCCTGCAGCCAGGATGGCCCGCTCCTCCTCATCGTGGAGTACGCCAAATACGGCTCCCTGCGGGGCTTCCTCCGCG
AGAGCCGCAAAGTGGGGCCTGGCTACCTGGGCAGTGGAGGCAGCCGCAACTCCAGCTCCCTGGACCACCCGGATGAGCGGGCCCTCACCA
TGGGCGACCTCATCTCATTTGCCTGGCAGATCTCACAGGGGATGCAGTATCTGGCCGAGATGAAGCTCGTTCATCGGGACTTGGCAGCCA
GAAACATCCTGGTAGCTGAGGGGCGGAAGATGAAGATTTCGGATTTCGGCTTGTCCCGAGATGTTTATGAAGAGGATTCCTACGTGAAGA
GGAGCCAGGGTCGGATTCCAGTTAAATGGATGGCAATTGAATCCCTTTTTGATCATATCTACACCACGCAAAGTGATGTATGGTCTTTTG
GTGTCCTGCTGTGGGAGATCGTGACCCTAGGGGGAAACCCCTATCCTGGGATTCCTCCTGAGCGGCTCTTCAACCTTCTGAAGACCGGCC
ACCGGATGGAGAGGCCAGACAACTGCAGCGAGGAGATGTACCGCCTGATGCTGCAATGCTGGAAGCAGGAGCCGGACAAAAGGCCGGTGT
TTGCGGACATCAGCAAAGACCTGGAGAAGATGATGGTTAAGAGGAGAGACTACTTGGACCTTGCGGCGTCCACTCCATCTGACTCCCTGA
TTTATGACGACGGCCTCTCAGAGGAGGAGACACCGCTGGTGGACTGTAATAATGCCCCCCTCCCTCGAGCCCTCCCTTCCACATGGATTG
AAAACAAACTCTATGGTAGAATTTCCCATGCATTTACTAGATTCTAGCACCGCTGTCCCCTTTGCACTATCCTTCCTCTCTGTGATGCTT
TTTAAAAATGTTTCTGGTCTGAACAAAACCAAAGTCTGCTCTGAACCTTTTTATTTGTAAATGTCTGACTTTGCATCCAGTTTACATTTA
GGCATTATTGCAACTATGTTTTTCTAAAAGGATGTGAAAATAAGTGTAATTACCACATTGCCCAGCAACTTAGGATGGTAGAGGAAAAAA
CAGATCAGGGCGGAACTCTCAGGGGAGACCAAGAACAGGTTGAATAAGGCGCTTCTGGGGTGGGAATCAAGTCATAGTACTTCTACTTTA
ACTAAGTGGATAAATATACAAATCTGGGGAGGTATTCAGTTGAGAAAGGAGCCACCAGCACCACTCAGCCTGCACTGGGAGCACAGCCAG
GTTCCCCCAGACCCCTCCTGGGCAGGCAGGTGCCTCTCAGAGGCCACCCGGCACTGGCGAGCAGCCACTGGCCAAGCCTCAGCCCCAGTC
CCAGCCACATGTCCTCCATCAGGGGTAGCGAGGTTGCAGGAGCTGGCTGGCCCTGGGAGGACGCACCCCCACTGCTGTTTTCACATCCTT
TCCCTTACCCACCTTCAGGACGGTTGTCACTTATGAAGTCAGTGCTAAAGCTGGAGCAGTTGCTTTTTGAAAGAACATGGTCTGTGGTGC

>63341_63341_7_PCM1-RET_PCM1_chr8_17851128_ENST00000524226_RET_chr10_43612031_ENST00000340058_length(amino acids)=1915AA_BP=1555
MATGGGPFEDGMNDQDLPNWSNENVDDRLNNMDWGAQQKKANRSSEKNKKKFGVESDKRVTNDISPESSPGVGRRRTKTPHTFPHSRYMS
QMSVPEQAELEKLKQRINFSDLDQRSIGSDSQGRATAANNKRQLSENRKPFNFLPMQINTNKSKDASTNPPNRETIGSAQCKELFASALS
NDLLQNCQVSEEDGRGEPAMESSQIVSRLVQIRDYITKASSMREDLVEKNERSANVERLTHLIDHLKEQEKSYMKFLKKILARDPQQEPM
EEIENLKKQHDLLKRMLQQQEQLRALQGRQAALLALQHKAEQAIAVMDDSVVAETAGSLSGVSITSELNEELNDLIQRFHNQLRDSQPPA
VPDNRRQAESLSLTREVSQSRKPSASERLPDEKVELFSKMRVLQEKKQKMDKLLGELHTLRDQHLNNSSSSPQRSVDQRSTSAPSASVGL
APVVNGESNSLTSSVPYPTASLVSQNESENEGHLNPSEKLQKLNEVRKRLNELRELVHYYEQTSDMMTDAVNENRKDEETEESEYDSEHE
NSEPVTNIRNPQVASTWNEVNSHSNAQCVSNNRDGRTVNSNCEINNRSAANIRALNMPPSLADCRYNREGEQEIHVAQGEDDEEEEEEAE
EEGVSGASLSSHRSSLVDEHPEDAEFEQKINRLMAAKQKLRQLQDLVAMVQDDDAAQGVISASASNLDDFYPAEEDTKQNSNNTRGNANK
TQKDTGVNEKAREKFYEAKLQQQQRELKQLQEERKKLIDIQEKIQALQTACPDLQLSAASVGNCPTKKYMPAVTSTPTVNQHETSTSKSV
FEPEDSSIVDNELWSEMRRHEMLREELRQRRKQLEALMAEHQRRQGLAETASPVAVSLRSDGSENLCTPQQSRTEKTMATWGGSTQCALD
EEGDEDGYLSEGIVRTDEEEEEEQDASSNDNFSVCPSNSVNHNSYNGKETKNRWKNNCPFSADENYRPLAKTRQQNISMQRQENLRWVSE
LSYVEEKEQWQEQINQLKKQLDFSVSICQTLMQDQQTLSCLLQTLLTGPYSVMPSNVASPQVHFIMHQLNQCYTQLTWQQNNVQRLKQML
NELMRQQNQHPEKPGGKERGSSASHPPSPSLFCPFSFPTQPVNLFNIPGFTNFSSFAPGMNFSPLFPSNFGDFSQNISTPSEQQQPLAQN
SSGKTEYMAFPKPFESSSSIGAEKPRNKKLPEEEVESSRTPWLYEQEGEVEKPFIKTGFSVSVEKSTSSNRKNQLDTNGRRRQFDEESLE
SFSSMPDPVDPTTVTKTFKTRKASAQASLASKDKTPKSKSKKRNSTQLKSRVKNIKTGSDFSMFEALRDTIYSEVATLISQNESRPHFLI
ELFHELQLLNTDYLRQRALYALQDIVSRHISESHEKGENVKSVNSGTWIASNSELTPSESLATTDDETFEKNFERETHKISEQNDADNAS
VLSVSSNFEPFATDDLGNTVIHLDQALARMREYERMKTEAESNSNMRCTCRIIEDGDGAGAGTTVNNLEETPVIENRSSQQPVSEVSTIP
CPRIDTQQLDRQIKAIMKEVIPFLKEDPKWEFPRKNLVLGKTLGEGEFGKVVKATAFHLKGRAGYTTVAVKMLKENASPSELRDLLSEFN
VLKQVNHPHVIKLYGACSQDGPLLLIVEYAKYGSLRGFLRESRKVGPGYLGSGGSRNSSSLDHPDERALTMGDLISFAWQISQGMQYLAE
MKLVHRDLAARNILVAEGRKMKISDFGLSRDVYEEDSYVKRSQGRIPVKWMAIESLFDHIYTTQSDVWSFGVLLWEIVTLGGNPYPGIPP
ERLFNLLKTGHRMERPDNCSEEMYRLMLQCWKQEPDKRPVFADISKDLEKMMVKRRDYLDLAASTPSDSLIYDDGLSEEETPLVDCNNAP

--------------------------------------------------------------
>63341_63341_8_PCM1-RET_PCM1_chr8_17851128_ENST00000524226_RET_chr10_43612031_ENST00000355710_length(transcript)=8015nt_BP=4724nt
AGCAGTTTCTGAGCTGCAAAAACTAGTTTCTAAACAGAGAGTTAATTGTTAAATCCAGTATGGCCACAGGAGGAGGTCCCTTTGAAGATG
GCATGAATGATCAGGATTTACCAAACTGGAGTAATGAGAATGTTGATGACAGGCTCAACAATATGGATTGGGGTGCCCAACAGAAGAAAG
CAAATAGATCATCAGAAAAGAATAAGAAAAAGTTTGGTGTAGAAAGTGATAAAAGAGTAACCAATGATATTTCTCCGGAGTCGTCACCAG
GAGTTGGAAGGCGAAGAACAAAGACTCCACATACGTTCCCACACAGTAGATACATGAGTCAGATGTCTGTCCCAGAGCAGGCAGAATTAG
AGAAACTGAAACAGCGGATAAACTTCAGTGATTTAGATCAGAGAAGCATTGGAAGTGATTCCCAAGGTAGAGCAACAGCTGCTAACAACA
AACGTCAGCTTAGTGAAAACCGAAAGCCCTTCAACTTTTTGCCTATGCAGATTAATACTAACAAGAGCAAAGATGCATCTACAAACCCCC
CAAACAGAGAAACGATTGGATCAGCACAGTGTAAAGAGTTGTTTGCTTCTGCTTTAAGTAATGACCTCTTGCAAAACTGTCAGGTGTCTG
AAGAAGATGGGAGGGGAGAACCTGCAATGGAGAGCAGCCAGATTGTAAGCAGGCTTGTTCAAATTCGCGATTATATTACTAAAGCTAGTT
CCATGCGGGAAGATCTTGTAGAGAAAAATGAGAGATCTGCTAATGTTGAGCGCCTTACTCATCTAATAGATCACCTTAAAGAACAAGAGA
AGTCATATATGAAATTTCTTAAAAAAATCCTTGCCAGAGATCCTCAGCAGGAGCCTATGGAAGAGATAGAAAATTTGAAGAAACAACATG
ATTTATTAAAAAGAATGTTACAACAGCAGGAGCAACTAAGAGCTCTACAGGGACGGCAGGCTGCACTTCTAGCTCTGCAACATAAAGCAG
AGCAAGCTATTGCAGTGATGGATGATTCTGTTGTTGCAGAAACTGCAGGTAGCTTATCTGGCGTCAGTATCACATCTGAACTAAATGAAG
AATTGAATGACTTAATTCAGCGTTTTCATAATCAGCTTCGTGATTCTCAGCCTCCAGCTGTTCCAGACAATAGAAGACAGGCAGAAAGTC
TTTCATTAACTAGGGAGGTTTCCCAGAGCAGGAAACCATCAGCTTCAGAACGTTTACCTGATGAGAAAGTCGAACTTTTTAGCAAAATGA
GAGTGCTACAGGAAAAGAAACAAAAAATGGACAAATTGCTTGGAGAACTTCATACACTTCGAGATCAGCATCTTAACAATTCATCATCCT
CTCCACAAAGGAGTGTCGATCAGAGAAGTACTTCAGCTCCCTCTGCTTCTGTAGGCTTGGCACCGGTTGTCAATGGAGAATCCAATAGCC
TCACATCATCTGTTCCTTATCCTACTGCTTCTCTAGTATCTCAGAATGAGAGTGAAAACGAAGGCCACCTCAATCCATCTGAAAAACTCC
AGAAGTTAAATGAAGTTCGAAAGAGATTGAATGAGCTAAGAGAATTAGTTCATTATTATGAACAAACGTCAGACATGATGACAGATGCTG
TGAATGAAAACAGGAAAGATGAAGAAACTGAAGAGTCAGAATATGATTCTGAGCATGAAAATTCCGAGCCTGTTACTAACATTCGAAATC
CACAAGTAGCTTCCACTTGGAATGAAGTAAATAGTCATAGTAATGCACAGTGTGTTTCTAATAATAGAGATGGGCGAACAGTTAATTCTA
ATTGTGAAATTAACAACAGATCTGCTGCCAACATAAGGGCTCTAAACATGCCTCCTTCTTTAGCAGATTGTCGATATAATAGAGAAGGGG
AACAGGAGATTCATGTTGCACAAGGTGAAGATGATGAGGAGGAGGAGGAAGAAGCAGAAGAGGAGGGAGTCAGTGGAGCTTCATTATCTA
GTCACAGGAGCAGTCTGGTTGATGAGCATCCAGAAGATGCTGAATTTGAACAGAAGATCAACCGACTTATGGCTGCAAAACAGAAACTTA
GACAGTTACAAGATCTTGTTGCTATGGTACAGGATGATGATGCAGCTCAAGGAGTTATCTCTGCCAGTGCATCAAATTTGGATGATTTCT
ACCCAGCAGAAGAAGACACCAAGCAAAATTCAAATAACACTAGAGGAAATGCCAATAAAACACAGAAAGATACTGGAGTAAATGAAAAGG
CAAGAGAGAAATTTTATGAGGCTAAACTACAGCAGCAACAGAGAGAGCTAAAACAATTGCAGGAAGAAAGAAAGAAACTGATTGACATTC
AGGAGAAAATTCAAGCATTGCAAACGGCATGCCCTGACTTACAGCTGTCAGCTGCTAGTGTGGGTAACTGTCCCACCAAAAAATATATGC
CAGCTGTTACTTCAACCCCAACTGTTAATCAACACGAGACCAGTACAAGCAAATCTGTTTTTGAGCCTGAAGATTCTTCAATAGTAGATA
ATGAGTTGTGGTCAGAAATGAGAAGACATGAAATGTTGAGGGAGGAGCTGCGACAGAGAAGAAAGCAGCTTGAAGCTCTGATGGCTGAAC
ATCAGAGGAGGCAAGGTCTAGCTGAAACTGCATCTCCAGTGGCTGTGTCATTGAGAAGTGATGGATCTGAGAACCTATGTACTCCTCAGC
AAAGTAGAACAGAAAAAACGATGGCAACTTGGGGAGGGTCTACCCAGTGTGCACTAGATGAAGAAGGAGATGAAGACGGTTACCTTTCTG
AAGGAATTGTTCGGACAGATGAAGAGGAGGAAGAAGAGCAAGATGCCAGTTCCAATGATAACTTTTCTGTGTGTCCTTCTAACAGTGTGA
ATCATAACTCCTACAATGGAAAGGAAACTAAAAATAGGTGGAAGAACAATTGCCCTTTTTCGGCAGATGAAAATTATCGTCCTTTAGCCA
AGACAAGGCAACAGAATATCAGCATGCAACGGCAAGAAAACCTTCGTTGGGTGTCAGAGCTCTCTTACGTAGAAGAGAAAGAACAATGGC
AAGAACAAATCAATCAGCTAAAGAAACAGCTTGATTTTAGTGTCAGTATTTGTCAGACTTTGATGCAAGACCAGCAGACTCTATCTTGTC
TGCTACAAACTCTTCTCACGGGTCCTTACAGTGTTATGCCCAGCAATGTTGCATCTCCTCAAGTACACTTCATAATGCACCAGTTGAACC
AGTGCTATACTCAGCTAACATGGCAACAGAATAATGTTCAGAGGTTGAAACAAATGCTAAATGAACTTATGCGCCAGCAAAATCAGCATC
CAGAAAAACCTGGAGGCAAGGAAAGAGGCAGTAGTGCATCGCACCCTCCTTCTCCCAGTTTATTTTGTCCTTTCAGCTTTCCAACACAGC
CTGTAAATCTCTTCAATATACCTGGATTTACTAACTTTTCATCATTTGCACCAGGTATGAATTTCAGCCCTTTATTTCCTTCTAATTTTG
GAGATTTTTCTCAGAATATCTCTACACCCAGTGAACAGCAGCAACCCTTAGCCCAGAATTCTTCAGGAAAAACAGAATATATGGCTTTTC
CAAAACCTTTTGAAAGCAGTTCCTCTATTGGAGCAGAGAAACCAAGGAATAAAAAACTGCCTGAAGAGGAGGTGGAAAGCAGTAGGACAC
CATGGTTATATGAACAAGAAGGTGAAGTAGAGAAACCATTTATCAAGACTGGATTTTCAGTGTCTGTAGAAAAATCTACAAGTAGTAACC
GCAAAAATCAATTAGATACAAACGGAAGAAGACGCCAGTTTGATGAAGAATCACTGGAAAGCTTTAGCAGTATGCCTGATCCAGTAGATC
CAACAACAGTGACTAAAACATTCAAGACAAGAAAAGCGTCTGCACAGGCCAGCCTGGCATCTAAAGATAAAACTCCCAAGTCAAAAAGTA
AGAAGAGGAATTCTACTCAGCTGAAAAGCAGAGTTAAAAACATCAAAACTGGGAGTGATTTTTCCATGTTTGAAGCTTTGCGAGATACTA
TTTATTCTGAAGTAGCTACATTAATTTCTCAAAATGAATCTCGTCCACATTTTCTTATTGAACTCTTCCATGAGCTGCAGCTACTAAACA
CAGACTACTTGAGACAGAGGGCTTTATATGCATTGCAGGACATAGTATCCAGACATATTTCTGAGAGCCATGAAAAAGGAGAAAATGTAA
AGTCAGTAAACTCTGGTACTTGGATAGCATCAAACTCAGAACTTACTCCTAGTGAGAGCCTTGCTACTACTGATGATGAAACTTTTGAGA
AGAACTTTGAAAGAGAAACCCATAAAATAAGTGAGCAAAATGATGCTGATAATGCTAGTGTCCTGTCTGTATCATCAAATTTTGAGCCTT
TTGCAACAGATGATCTAGGTAACACCGTGATTCACTTAGATCAAGCATTAGCCAGAATGAGAGAATATGAGCGTATGAAGACTGAGGCTG
AAAGTAACTCAAATATGAGATGCACCTGCAGGATTATTGAGGATGGAGATGGTGCTGGTGCAGGTACTACAGTTAATAATTTAGAAGAAA
CTCCCGTTATTGAAAATCGTAGTTCACAACAACCTGTAAGTGAAGTTTCTACCATCCCATGTCCTAGAATTGATACTCAGCAGCTGGACC
GGCAAATTAAAGCAATTATGAAAGAAGTCATTCCTTTTTTGAAGGAGGATCCAAAGTGGGAATTCCCTCGGAAGAACTTGGTTCTTGGAA
AAACTCTAGGAGAAGGCGAATTTGGAAAAGTGGTCAAGGCAACGGCCTTCCATCTGAAAGGCAGAGCAGGGTACACCACGGTGGCCGTGA
AGATGCTGAAAGAGAACGCCTCCCCGAGTGAGCTGCGAGACCTGCTGTCAGAGTTCAACGTCCTGAAGCAGGTCAACCACCCACATGTCA
TCAAATTGTATGGGGCCTGCAGCCAGGATGGCCCGCTCCTCCTCATCGTGGAGTACGCCAAATACGGCTCCCTGCGGGGCTTCCTCCGCG
AGAGCCGCAAAGTGGGGCCTGGCTACCTGGGCAGTGGAGGCAGCCGCAACTCCAGCTCCCTGGACCACCCGGATGAGCGGGCCCTCACCA
TGGGCGACCTCATCTCATTTGCCTGGCAGATCTCACAGGGGATGCAGTATCTGGCCGAGATGAAGCTCGTTCATCGGGACTTGGCAGCCA
GAAACATCCTGGTAGCTGAGGGGCGGAAGATGAAGATTTCGGATTTCGGCTTGTCCCGAGATGTTTATGAAGAGGATTCCTACGTGAAGA
GGAGCCAGGGTCGGATTCCAGTTAAATGGATGGCAATTGAATCCCTTTTTGATCATATCTACACCACGCAAAGTGATGTATGGTCTTTTG
GTGTCCTGCTGTGGGAGATCGTGACCCTAGGGGGAAACCCCTATCCTGGGATTCCTCCTGAGCGGCTCTTCAACCTTCTGAAGACCGGCC
ACCGGATGGAGAGGCCAGACAACTGCAGCGAGGAGATGTACCGCCTGATGCTGCAATGCTGGAAGCAGGAGCCGGACAAAAGGCCGGTGT
TTGCGGACATCAGCAAAGACCTGGAGAAGATGATGGTTAAGAGGAGAGACTACTTGGACCTTGCGGCGTCCACTCCATCTGACTCCCTGA
TTTATGACGACGGCCTCTCAGAGGAGGAGACACCGCTGGTGGACTGTAATAATGCCCCCCTCCCTCGAGCCCTCCCTTCCACATGGATTG
AAAACAAACTCTATGGCATGTCAGACCCGAACTGGCCTGGAGAGAGTCCTGTACCACTCACGAGAGCTGATGGCACTAACACTGGGTTTC
CAAGATATCCAAATGATAGTGTATATGCTAACTGGATGCTTTCACCCTCAGCGGCAAAATTAATGGACACGTTTGATAGTTAACATTTCT
TTGTGAAAGGTAATGGACTCACAAGGGGAAGAAACATGCTGAGAATGGAAAGTCTACCGGCCCTTTCTTTGTGAACGTCACATTGGCCGA
GCCGTGTTCAGTTCCCAGGTGGCAGACTCGTTTTTGGTAGTTTGTTTTAACTTCCAAGGTGGTTTTACTTCTGATAGCCGGTGATTTTCC
CTCCTAGCAGACATGCCACACCGGGTAAGAGCTCTGAGTCTTAGTGGTTAAGCATTCCTTTCTCTTCAGTGCCCAGCAGCACCCAGTGTT
GGTCTGTGTCCATCAGTGACCACCAACATTCTGTGTTCACATGTGTGGGTCCAACACTTACTACCTGGTGTATGAAATTGGACCTGAACT
GTTGGATTTTTCTAGTTGCCGCCAAACAAGGCAAAAAAATTTAAACATGAAGCACACACACAAAAAAGGCAGTAGGAAAAATGCTGGCCC
TGATGACCTGTCCTTATTCAGAATGAGAGACTGCGGGGGGGGCCTGGGGGTAGTGTCAATGCCCCTCCAGGGCTGGAGGGGAAGAGGGGC
CCCGAGGATGGGCCTGGGCTCAGCATTCGAGATCTTGAGAATGATTTTTTTTAAATCATGCAACCTTTCCTTAGGAAGACATTTGGTTTT
CATCATGATTAAGATGATTCCTAGATTTAGCACAATGGAGAGATTCCATGCCATCTTTACTATGTGGATGGTGGTATCAGGGAAGAGGGC
TCACAAGACACATTTGTCCCCCGGGCCCACCACATCATCCTCACGTGTTCGGTACTGAGCAGCCACTACCCCTGATGAGAACAGTATGAA
GAAAGGGGGCTGTTGGAGTCCCAGAATTGCTGACAGCAGAGGCTTTGCTGCTGTGAATCCCACCTGCCACCAGCCTGCAGCACACCCCAC
AGCCAAGTAGAGGCGAAAGCAGTGGCTCATCCTACCTGTTAGGAGCAGGTAGGGCTTGTACTCACTTTAATTTGAATCTTATCAACTTAC
TCATAAAGGGACAGGCTAGCTAGCTGTGTTAGAAGTAGCAATGACAATGACCAAGGACTGCTACACCTCTGATTACAATTCTGATGTGAA
AAAGATGGTGTTTGGCTCTTATAGAGCCTGTGTGAAAGGCCCATGGATCAGCTCTTCCTGTGTTTGTAATTTAATGCTGCTACAAGATGT
TTCTGTTTCTTAGATTCTGACCATGACTCATAAGCTTCTTGTCATTCTTCATTGCTTGTTTGTGGTCACAGATGCACAACACTCCTCCAG
TCTTGTGGGGGCAGCTTTTGGGAAGTCTCAGCAGCTCTTCTGGCTGTGTTGTCAGCACTGTAACTTCGCAGAAAAGAGTCGGATTACCAA
AACACTGCCTGCTCTTCAGACTTAAAGCACTGATAGGACTTAAAATAGTCTCATTCAAATACTGTATTTTATATAGGCATTTCACAAAAA
CAGCAAAATTGTGGCATTTTGTGAGGCCAAGGCTTGGATGCGTGTGTAATAGAGCCTTGTGGTGTGTGCGCACACACCCAGAGGGAGAGT
TTGAAAAATGCTTATTGGACACGTAACCTGGCTCTAATTTGGGCTGTTTTTCAGATACACTGTGATAAGTTCTTTTACAAATATCTATAG
ACATGGTAAACTTTTGGTTTTCAGATATGCTTAATGATAGTCTTACTAAATGCAGAAATAAGAATAAACTTTCTCAAATTATTAAAAATG
CCTACACAGTAAGTGTGAATTGCTGCAACAGGTTTGTTCTCAGGAGGGTAAGAACTCCAGGTCTAAACAGCTGACCCAGTGATGGGGAAT
TTATCCTTGACCAATTTATCCTTGACCAATAACCTAATTGTCTATTCCTGAGTTATAAAAGTCCCCATCCTTATTAGCTCTACTGGAATT
TTCATACACGTAAATGCAGAAGTTACTAAGTATTAAGTATTACTGAGTATTAAGTAGTAATCTGTCAGTTATTAAAATTTGTAAAATCTA
TTTATGAAAGGTCATTAAACCAGATCATGTTCCTTTTTTTGTAATCAAGGTGACTAAGAAAATCAGTTGTGTAAATAAAATCATGTATCA

>63341_63341_8_PCM1-RET_PCM1_chr8_17851128_ENST00000524226_RET_chr10_43612031_ENST00000355710_length(amino acids)=1957AA_BP=1555
MATGGGPFEDGMNDQDLPNWSNENVDDRLNNMDWGAQQKKANRSSEKNKKKFGVESDKRVTNDISPESSPGVGRRRTKTPHTFPHSRYMS
QMSVPEQAELEKLKQRINFSDLDQRSIGSDSQGRATAANNKRQLSENRKPFNFLPMQINTNKSKDASTNPPNRETIGSAQCKELFASALS
NDLLQNCQVSEEDGRGEPAMESSQIVSRLVQIRDYITKASSMREDLVEKNERSANVERLTHLIDHLKEQEKSYMKFLKKILARDPQQEPM
EEIENLKKQHDLLKRMLQQQEQLRALQGRQAALLALQHKAEQAIAVMDDSVVAETAGSLSGVSITSELNEELNDLIQRFHNQLRDSQPPA
VPDNRRQAESLSLTREVSQSRKPSASERLPDEKVELFSKMRVLQEKKQKMDKLLGELHTLRDQHLNNSSSSPQRSVDQRSTSAPSASVGL
APVVNGESNSLTSSVPYPTASLVSQNESENEGHLNPSEKLQKLNEVRKRLNELRELVHYYEQTSDMMTDAVNENRKDEETEESEYDSEHE
NSEPVTNIRNPQVASTWNEVNSHSNAQCVSNNRDGRTVNSNCEINNRSAANIRALNMPPSLADCRYNREGEQEIHVAQGEDDEEEEEEAE
EEGVSGASLSSHRSSLVDEHPEDAEFEQKINRLMAAKQKLRQLQDLVAMVQDDDAAQGVISASASNLDDFYPAEEDTKQNSNNTRGNANK
TQKDTGVNEKAREKFYEAKLQQQQRELKQLQEERKKLIDIQEKIQALQTACPDLQLSAASVGNCPTKKYMPAVTSTPTVNQHETSTSKSV
FEPEDSSIVDNELWSEMRRHEMLREELRQRRKQLEALMAEHQRRQGLAETASPVAVSLRSDGSENLCTPQQSRTEKTMATWGGSTQCALD
EEGDEDGYLSEGIVRTDEEEEEEQDASSNDNFSVCPSNSVNHNSYNGKETKNRWKNNCPFSADENYRPLAKTRQQNISMQRQENLRWVSE
LSYVEEKEQWQEQINQLKKQLDFSVSICQTLMQDQQTLSCLLQTLLTGPYSVMPSNVASPQVHFIMHQLNQCYTQLTWQQNNVQRLKQML
NELMRQQNQHPEKPGGKERGSSASHPPSPSLFCPFSFPTQPVNLFNIPGFTNFSSFAPGMNFSPLFPSNFGDFSQNISTPSEQQQPLAQN
SSGKTEYMAFPKPFESSSSIGAEKPRNKKLPEEEVESSRTPWLYEQEGEVEKPFIKTGFSVSVEKSTSSNRKNQLDTNGRRRQFDEESLE
SFSSMPDPVDPTTVTKTFKTRKASAQASLASKDKTPKSKSKKRNSTQLKSRVKNIKTGSDFSMFEALRDTIYSEVATLISQNESRPHFLI
ELFHELQLLNTDYLRQRALYALQDIVSRHISESHEKGENVKSVNSGTWIASNSELTPSESLATTDDETFEKNFERETHKISEQNDADNAS
VLSVSSNFEPFATDDLGNTVIHLDQALARMREYERMKTEAESNSNMRCTCRIIEDGDGAGAGTTVNNLEETPVIENRSSQQPVSEVSTIP
CPRIDTQQLDRQIKAIMKEVIPFLKEDPKWEFPRKNLVLGKTLGEGEFGKVVKATAFHLKGRAGYTTVAVKMLKENASPSELRDLLSEFN
VLKQVNHPHVIKLYGACSQDGPLLLIVEYAKYGSLRGFLRESRKVGPGYLGSGGSRNSSSLDHPDERALTMGDLISFAWQISQGMQYLAE
MKLVHRDLAARNILVAEGRKMKISDFGLSRDVYEEDSYVKRSQGRIPVKWMAIESLFDHIYTTQSDVWSFGVLLWEIVTLGGNPYPGIPP
ERLFNLLKTGHRMERPDNCSEEMYRLMLQCWKQEPDKRPVFADISKDLEKMMVKRRDYLDLAASTPSDSLIYDDGLSEEETPLVDCNNAP

--------------------------------------------------------------
>63341_63341_9_PCM1-RET_PCM1_chr8_17851129_ENST00000325083_RET_chr10_43612030_ENST00000340058_length(transcript)=7099nt_BP=5266nt
TCCGGCGGGTCACATGACTCCAGTCTAGCTCGCATTGCGGCTCCCGCCCGGGCGAGTTCTCGCCCCCGCGCGGCCGTTGCCGAGGAGACG
GCGCATGTCCCGCCGCGCGTTGCCCCCTCTGCAGTACCCCCGCCCCTCTTCTCCCACCACAATGAGATCCTAAGATGGCGGTGGCTGCGG
CGGTTGGCGCTGCGTAGCTGAGGTCGAAAAGGCGGCCACTGGGGCCGAGGCAGCCAGGAAACGTGTGGGCCTCTCTGCTGCGGTCTCCGA
GGGCCGACCGCTGCCGGCGGCGGGTCGTGGGGGCTGACTGTCGCTCTGCCTTTGACAGGAGAGGCTGCTTCTTGTAGAGGAAACAGCTTT
GAAGTGTGGAGCGGGAAAGGAGCAGTTTCTGAGCTGCAAAAACTAGTTTCTAAACAGAGAGTTAATTGTTAAATCCAGTATGGCCACAGG
AGGAGGTCCCTTTGAAGATGGCATGAATGATCAGGATTTACCAAACTGGAGTAATGAGAATGTTGATGACAGGCTCAACAATATGGATTG
GGGTGCCCAACAGAAGAAAGCAAATAGATCATCAGAAAAGAATAAGAAAAAGTTTGGTGTAGAAAGTGATAAAAGAGTAACCAATGATAT
TTCTCCGGAGTCGTCACCAGGAGTTGGAAGGCGAAGAACAAAGACTCCACATACGTTCCCACACAGTAGATACATGAGTCAGATGTCTGT
CCCAGAGCAGGCAGAATTAGAGAAACTGAAACAGCGGATAAACTTCAGTGATTTAGATCAGAGAAGCATTGGAAGTGATTCCCAAGGTAG
AGCAACAGCTGCTAACAACAAACGTCAGCTTAGTGAAAACCGAAAGCCCTTCAACTTTTTGCCTATGCAGATTAATACTAACAAGAGCAA
AGATGCATCTACAAACCCCCCAAACAGAGAAACGATTGGATCAGCACAGTGTAAAGAGTTGTTTGCTTCTGCTTTAAGTAATGACCTCTT
GCAAAACTGTCAGGTGTCTGAAGAAGATGGGAGGGGAGAACCTGCAATGGAGAGCAGCCAGATTGTAAGCAGGCTTGTTCAAATTCGCGA
TTATATTACTAAAGCTAGTTCCATGCGGGAAGATCTTGTAGAGAAAAATGAGAGATCTGCTAATGTTGAGCGCCTTACTCATCTAATAGA
TCACCTTAAAGAACAAGAGAAGTCATATATGAAATTTCTTAAAAAAATCCTTGCCAGAGATCCTCAGCAGGAGCCTATGGAAGAGATAGA
AAATTTGAAGAAACAACATGATTTATTAAAAAGAATGTTACAACAGCAGGAGCAACTAAGAGCTCTACAGGGACGGCAGGCTGCACTTCT
AGCTCTGCAACATAAAGCAGAGCAAGCTATTGCAGTGATGGATGATTCTGTTGTTGCAGAAACTGCAGGTAGCTTATCTGGCGTCAGTAT
CACATCTGAACTAAATGAAGAATTGAATGACTTAATTCAGCGTTTTCATAATCAGCTTCGTGATTCTCAGCCTCCAGCTGTTCCAGACAA
TAGAAGACAGGCAGAAAGTCTTTCATTAACTAGGGAGGTTTCCCAGAGCAGGAAACCATCAGCTTCAGAACGTTTACCTGATGAGAAAGT
CGAACTTTTTAGCAAAATGAGAGTGCTACAGGAAAAGAAACAAAAAATGGACAAATTGCTTGGAGAACTTCATACACTTCGAGATCAGCA
TCTTAACAATTCATCATCCTCTCCACAAAGGAGTGTCGATCAGAGAAGTACTTCAGCTCCCTCTGCTTCTGTAGGCTTGGCACCGGTTGT
CAATGGAGAATCCAATAGCCTCACATCATCTGTTCCTTATCCTACTGCTTCTCTAGTATCTCAGAATGAGAGTGAAAACGAAGGCCACCT
CAATCCATCTGAAAAACTCCAGAAGTTAAATGAAGTTCGAAAGAGATTGAATGAGCTAAGAGAATTAGTTCATTATTATGAACAAACGTC
AGACATGATGACAGATGCTGTGAATGAAAACAGGAAAGATGAAGAAACTGAAGAGTCAGAATATGATTCTGAGCATGAAAATTCCGAGCC
TGTTACTAACATTCGAAATCCACAAGTAGCTTCCACTTGGAATGAAGTAAATAGTCATAGTAATGCACAGTGTGTTTCTAATAATAGAGA
TGGGCGAACAGTTAATTCTAATTGTGAAATTAACAACAGATCTGCTGCCAACATAAGGGCTCTAAACATGCCTCCTTCTTTAGATTGTCG
ATATAATAGAGAAGGGGAACAGGAGATTCATGTTGCACAAGGTGAAGATGATGAGGAGGAGGAGGAAGAAGCAGAAGAGGAGGGAGTCAG
TGGAGCTTCATTATCTAGTCACAGGAGCAGTCTGGTTGATGAGCATCCAGAAGATGCTGAATTTGAACAGAAGATCAACCGACTTATGGC
TGCAAAACAGAAACTTAGACAGTTACAAGATCTTGTTGCTATGGTACAGGATGATGATGCAGCTCAAGGAGTTATCTCTGCCAGTGCATC
AAATTTGGATGATTTCTACCCAGCAGAAGAAGACACCAAGCAAAATTCAAATAACACTAGAGGAAATGCCAATAAAACACAGAAAGATAC
TGGAGTAAATGAAAAGGCAAGAGAGAAATTTTATGAGGCTAAACTACAGCAGCAACAGAGAGAGCTAAAACAATTGCAGGAAGAAAGAAA
GAAACTGATTGACATTCAGGAGAAAATTCAAGCATTGCAAACGGCATGCCCTGACTTACAGCTGTCAGCTGCTAGTGTGGGTAACTGTCC
CACCAAAAAATATATGCCAGCTGTTACTTCAACCCCAACTGTTAATCAACACGAGACCAGTACAAGCAAATCTGTTTTTGAGCCTGAAGA
TTCTTCAATAGTAGATAATGAGTTGTGGTCAGAAATGAGAAGACATGAAATGTTGAGGGAGGAGCTGCGACAGAGAAGAAAGCAGCTTGA
AGCTCTGATGGCTGAACATCAGAGGAGGCAAGGTCTAGCTGAAACTGCATCTCCAGTGGCTGTGTCATTGAGAAGTGATGGATCTGAGAA
CCTATGTACTCCTCAGCAAAGTAGAACAGAAAAAACGATGGCAACTTGGGGAGGGTCTACCCAGTGTGCACTAGATGAAGAAGGAGATGA
AGACGGTTACCTTTCTGAAGGAATTGTTCGGACAGATGAAGAGGAGGAAGAAGAGCAAGATGCCAGTTCCAATGATAACTTTTCTGTGTG
TCCTTCTAACAGTGTGAATCATAACTCCTACAATGGAAAGGAAACTAAAAATAGGTGGAAGAACAATTGCCCTTTTTCGGCAGATGAAAA
TTATCGTCCTTTAGCCAAGACAAGGCAACAGAATATCAGCATGCAACGGCAAGAAAACCTTCGTTGGGTGTCAGAGCTCTCTTACGTAGA
AGAGAAAGAACAATGGCAAGAACAAATCAATCAGCTAAAGAAACAGCTTGATTTTAGTGTCAGTATTTGTCAGACTTTGATGCAAGACCA
GCAGACTCTATCTTGTCTGCTACAAACTCTTCTCACGGGTCCTTACAGTGTTATGCCCAGCAATGTTGCATCTCCTCAAGTACACTTCAT
AATGCACCAGTTGAACCAGTGCTATACTCAGCTAACATGGCAACAGAATAATGTTCAGAGGTTGAAACAAATGCTAAATGAACTTATGCG
CCAGCAAAATCAGCATCCAGAAAAACCTGGAGGCAAGGAAAGAGGCAGTAGTGCATCGCACCCTCCTTCTCCCAGTTTATTTTGTCCTTT
CAGCTTTCCAACACAGCCTGTAAATCTCTTCAATATACCTGGATTTACTAACTTTTCATCATTTGCACCAGGTATGAATTTCAGCCCTTT
ATTTCCTTCTAATTTTGGAGATTTTTCTCAGAATATCTCTACACCCAGTGAACAGCAGCAACCCTTAGCCCAGAATTCTTCAGGAAAAAC
AGAATATATGGCTTTTCCAAAACCTTTTGAAAGCAGTTCCTCTATTGGAGCAGAGAAACCAAGGAATAAAAAACTGCCTGAAGAGGAGGT
GGAAAGCAGTAGGACACCATGGTTATATGAACAAGAAGGTGAAGTAGAGAAACCATTTATCAAGACTGGATTTTCAGTGTCTGTAGAAAA
ATCTACAAGTAGTAACCGCAAAAATCAATTAGATACAAACGGAAGAAGACGCCAGTTTGATGAAGAATCACTGGAAAGCTTTAGCAGTAT
GCCTGATCCAGTAGATCCAACAACAGTGACTAAAACATTCAAGACAAGAAAAGCGTCTGCACAGGCCAGCCTGGCATCTAAAGATAAAAC
TCCCAAGTCAAAAAGTAAGAAGAGGAATTCTACTCAGCTGAAAAGCAGAGTTAAAAACATCAGGTATGAAAGTGCCAGTATGTCTAGCAC
ATGTGAACCTTGCAAAAGTAGGAACAGACATTCAGCCCAGACTGAAGAGCCTGTTCAAGCAAAAGTATTCAGCAGAAAGAATCATGAGCA
ACTGGAAAAAATAATAAAATGTAATAGGTCTACAGAAATATCTTCAGAAACTGGGAGTGATTTTTCCATGTTTGAAGCTTTGCGAGATAC
TATTTATTCTGAAGTAGCTACATTAATTTCTCAAAATGAATCTCGTCCACATTTTCTTATTGAACTCTTCCATGAGCTGCAGCTACTAAA
CACAGACTACTTGAGACAGAGGGCTTTATATGCATTGCAGGACATAGTATCCAGACATATTTCTGAGAGCCATGAAAAAGGAGAAAATGT
AAAGTCAGTAAACTCTGGTACTTGGATAGCATCAAACTCAGAACTTACTCCTAGTGAGAGCCTTGCTACTACTGATGATGAAACTTTTGA
GAAGAACTTTGAAAGAGAAACCCATAAAATAAGTGAGCAAAATGATGCTGATAATGCTAGTGTCCTGTCTGTATCATCAAATTTTGAGCC
TTTTGCAACAGATGATCTAGGTAACACCGTGATTCACTTAGATCAAGCATTAGCCAGAATGAGAGAATATGAGCGTATGAAGACTGAGGC
TGAAAGTAACTCAAATATGAGATGCACCTGCAGGATTATTGAGGATGGAGATGGTGCTGGTGCAGGTACTACAGTTAATAATTTAGAAGA
AACTCCCGTTATTGAAAATCGTAGTTCACAACAACCTGTAAGTGAAGTTTCTACCATCCCATGTCCTAGAATTGATACTCAGCAGCTGGA
CCGGCAAATTAAAGCAATTATGAAAGAAGTCATTCCTTTTTTGAAGGAGGATCCAAAGTGGGAATTCCCTCGGAAGAACTTGGTTCTTGG
AAAAACTCTAGGAGAAGGCGAATTTGGAAAAGTGGTCAAGGCAACGGCCTTCCATCTGAAAGGCAGAGCAGGGTACACCACGGTGGCCGT
GAAGATGCTGAAAGAGAACGCCTCCCCGAGTGAGCTGCGAGACCTGCTGTCAGAGTTCAACGTCCTGAAGCAGGTCAACCACCCACATGT
CATCAAATTGTATGGGGCCTGCAGCCAGGATGGCCCGCTCCTCCTCATCGTGGAGTACGCCAAATACGGCTCCCTGCGGGGCTTCCTCCG
CGAGAGCCGCAAAGTGGGGCCTGGCTACCTGGGCAGTGGAGGCAGCCGCAACTCCAGCTCCCTGGACCACCCGGATGAGCGGGCCCTCAC
CATGGGCGACCTCATCTCATTTGCCTGGCAGATCTCACAGGGGATGCAGTATCTGGCCGAGATGAAGCTCGTTCATCGGGACTTGGCAGC
CAGAAACATCCTGGTAGCTGAGGGGCGGAAGATGAAGATTTCGGATTTCGGCTTGTCCCGAGATGTTTATGAAGAGGATTCCTACGTGAA
GAGGAGCCAGGGTCGGATTCCAGTTAAATGGATGGCAATTGAATCCCTTTTTGATCATATCTACACCACGCAAAGTGATGTATGGTCTTT
TGGTGTCCTGCTGTGGGAGATCGTGACCCTAGGGGGAAACCCCTATCCTGGGATTCCTCCTGAGCGGCTCTTCAACCTTCTGAAGACCGG
CCACCGGATGGAGAGGCCAGACAACTGCAGCGAGGAGATGTACCGCCTGATGCTGCAATGCTGGAAGCAGGAGCCGGACAAAAGGCCGGT
GTTTGCGGACATCAGCAAAGACCTGGAGAAGATGATGGTTAAGAGGAGAGACTACTTGGACCTTGCGGCGTCCACTCCATCTGACTCCCT
GATTTATGACGACGGCCTCTCAGAGGAGGAGACACCGCTGGTGGACTGTAATAATGCCCCCCTCCCTCGAGCCCTCCCTTCCACATGGAT
TGAAAACAAACTCTATGGTAGAATTTCCCATGCATTTACTAGATTCTAGCACCGCTGTCCCCTTTGCACTATCCTTCCTCTCTGTGATGC
TTTTTAAAAATGTTTCTGGTCTGAACAAAACCAAAGTCTGCTCTGAACCTTTTTATTTGTAAATGTCTGACTTTGCATCCAGTTTACATT
TAGGCATTATTGCAACTATGTTTTTCTAAAAGGATGTGAAAATAAGTGTAATTACCACATTGCCCAGCAACTTAGGATGGTAGAGGAAAA
AACAGATCAGGGCGGAACTCTCAGGGGAGACCAAGAACAGGTTGAATAAGGCGCTTCTGGGGTGGGAATCAAGTCATAGTACTTCTACTT
TAACTAAGTGGATAAATATACAAATCTGGGGAGGTATTCAGTTGAGAAAGGAGCCACCAGCACCACTCAGCCTGCACTGGGAGCACAGCC
AGGTTCCCCCAGACCCCTCCTGGGCAGGCAGGTGCCTCTCAGAGGCCACCCGGCACTGGCGAGCAGCCACTGGCCAAGCCTCAGCCCCAG
TCCCAGCCACATGTCCTCCATCAGGGGTAGCGAGGTTGCAGGAGCTGGCTGGCCCTGGGAGGACGCACCCCCACTGCTGTTTTCACATCC
TTTCCCTTACCCACCTTCAGGACGGTTGTCACTTATGAAGTCAGTGCTAAAGCTGGAGCAGTTGCTTTTTGAAAGAACATGGTCTGTGGT

>63341_63341_9_PCM1-RET_PCM1_chr8_17851129_ENST00000325083_RET_chr10_43612030_ENST00000340058_length(amino acids)=1969AA_BP=1609
MATGGGPFEDGMNDQDLPNWSNENVDDRLNNMDWGAQQKKANRSSEKNKKKFGVESDKRVTNDISPESSPGVGRRRTKTPHTFPHSRYMS
QMSVPEQAELEKLKQRINFSDLDQRSIGSDSQGRATAANNKRQLSENRKPFNFLPMQINTNKSKDASTNPPNRETIGSAQCKELFASALS
NDLLQNCQVSEEDGRGEPAMESSQIVSRLVQIRDYITKASSMREDLVEKNERSANVERLTHLIDHLKEQEKSYMKFLKKILARDPQQEPM
EEIENLKKQHDLLKRMLQQQEQLRALQGRQAALLALQHKAEQAIAVMDDSVVAETAGSLSGVSITSELNEELNDLIQRFHNQLRDSQPPA
VPDNRRQAESLSLTREVSQSRKPSASERLPDEKVELFSKMRVLQEKKQKMDKLLGELHTLRDQHLNNSSSSPQRSVDQRSTSAPSASVGL
APVVNGESNSLTSSVPYPTASLVSQNESENEGHLNPSEKLQKLNEVRKRLNELRELVHYYEQTSDMMTDAVNENRKDEETEESEYDSEHE
NSEPVTNIRNPQVASTWNEVNSHSNAQCVSNNRDGRTVNSNCEINNRSAANIRALNMPPSLDCRYNREGEQEIHVAQGEDDEEEEEEAEE
EGVSGASLSSHRSSLVDEHPEDAEFEQKINRLMAAKQKLRQLQDLVAMVQDDDAAQGVISASASNLDDFYPAEEDTKQNSNNTRGNANKT
QKDTGVNEKAREKFYEAKLQQQQRELKQLQEERKKLIDIQEKIQALQTACPDLQLSAASVGNCPTKKYMPAVTSTPTVNQHETSTSKSVF
EPEDSSIVDNELWSEMRRHEMLREELRQRRKQLEALMAEHQRRQGLAETASPVAVSLRSDGSENLCTPQQSRTEKTMATWGGSTQCALDE
EGDEDGYLSEGIVRTDEEEEEEQDASSNDNFSVCPSNSVNHNSYNGKETKNRWKNNCPFSADENYRPLAKTRQQNISMQRQENLRWVSEL
SYVEEKEQWQEQINQLKKQLDFSVSICQTLMQDQQTLSCLLQTLLTGPYSVMPSNVASPQVHFIMHQLNQCYTQLTWQQNNVQRLKQMLN
ELMRQQNQHPEKPGGKERGSSASHPPSPSLFCPFSFPTQPVNLFNIPGFTNFSSFAPGMNFSPLFPSNFGDFSQNISTPSEQQQPLAQNS
SGKTEYMAFPKPFESSSSIGAEKPRNKKLPEEEVESSRTPWLYEQEGEVEKPFIKTGFSVSVEKSTSSNRKNQLDTNGRRRQFDEESLES
FSSMPDPVDPTTVTKTFKTRKASAQASLASKDKTPKSKSKKRNSTQLKSRVKNIRYESASMSSTCEPCKSRNRHSAQTEEPVQAKVFSRK
NHEQLEKIIKCNRSTEISSETGSDFSMFEALRDTIYSEVATLISQNESRPHFLIELFHELQLLNTDYLRQRALYALQDIVSRHISESHEK
GENVKSVNSGTWIASNSELTPSESLATTDDETFEKNFERETHKISEQNDADNASVLSVSSNFEPFATDDLGNTVIHLDQALARMREYERM
KTEAESNSNMRCTCRIIEDGDGAGAGTTVNNLEETPVIENRSSQQPVSEVSTIPCPRIDTQQLDRQIKAIMKEVIPFLKEDPKWEFPRKN
LVLGKTLGEGEFGKVVKATAFHLKGRAGYTTVAVKMLKENASPSELRDLLSEFNVLKQVNHPHVIKLYGACSQDGPLLLIVEYAKYGSLR
GFLRESRKVGPGYLGSGGSRNSSSLDHPDERALTMGDLISFAWQISQGMQYLAEMKLVHRDLAARNILVAEGRKMKISDFGLSRDVYEED
SYVKRSQGRIPVKWMAIESLFDHIYTTQSDVWSFGVLLWEIVTLGGNPYPGIPPERLFNLLKTGHRMERPDNCSEEMYRLMLQCWKQEPD

--------------------------------------------------------------
>63341_63341_10_PCM1-RET_PCM1_chr8_17851129_ENST00000325083_RET_chr10_43612030_ENST00000355710_length(transcript)=8557nt_BP=5266nt
TCCGGCGGGTCACATGACTCCAGTCTAGCTCGCATTGCGGCTCCCGCCCGGGCGAGTTCTCGCCCCCGCGCGGCCGTTGCCGAGGAGACG
GCGCATGTCCCGCCGCGCGTTGCCCCCTCTGCAGTACCCCCGCCCCTCTTCTCCCACCACAATGAGATCCTAAGATGGCGGTGGCTGCGG
CGGTTGGCGCTGCGTAGCTGAGGTCGAAAAGGCGGCCACTGGGGCCGAGGCAGCCAGGAAACGTGTGGGCCTCTCTGCTGCGGTCTCCGA
GGGCCGACCGCTGCCGGCGGCGGGTCGTGGGGGCTGACTGTCGCTCTGCCTTTGACAGGAGAGGCTGCTTCTTGTAGAGGAAACAGCTTT
GAAGTGTGGAGCGGGAAAGGAGCAGTTTCTGAGCTGCAAAAACTAGTTTCTAAACAGAGAGTTAATTGTTAAATCCAGTATGGCCACAGG
AGGAGGTCCCTTTGAAGATGGCATGAATGATCAGGATTTACCAAACTGGAGTAATGAGAATGTTGATGACAGGCTCAACAATATGGATTG
GGGTGCCCAACAGAAGAAAGCAAATAGATCATCAGAAAAGAATAAGAAAAAGTTTGGTGTAGAAAGTGATAAAAGAGTAACCAATGATAT
TTCTCCGGAGTCGTCACCAGGAGTTGGAAGGCGAAGAACAAAGACTCCACATACGTTCCCACACAGTAGATACATGAGTCAGATGTCTGT
CCCAGAGCAGGCAGAATTAGAGAAACTGAAACAGCGGATAAACTTCAGTGATTTAGATCAGAGAAGCATTGGAAGTGATTCCCAAGGTAG
AGCAACAGCTGCTAACAACAAACGTCAGCTTAGTGAAAACCGAAAGCCCTTCAACTTTTTGCCTATGCAGATTAATACTAACAAGAGCAA
AGATGCATCTACAAACCCCCCAAACAGAGAAACGATTGGATCAGCACAGTGTAAAGAGTTGTTTGCTTCTGCTTTAAGTAATGACCTCTT
GCAAAACTGTCAGGTGTCTGAAGAAGATGGGAGGGGAGAACCTGCAATGGAGAGCAGCCAGATTGTAAGCAGGCTTGTTCAAATTCGCGA
TTATATTACTAAAGCTAGTTCCATGCGGGAAGATCTTGTAGAGAAAAATGAGAGATCTGCTAATGTTGAGCGCCTTACTCATCTAATAGA
TCACCTTAAAGAACAAGAGAAGTCATATATGAAATTTCTTAAAAAAATCCTTGCCAGAGATCCTCAGCAGGAGCCTATGGAAGAGATAGA
AAATTTGAAGAAACAACATGATTTATTAAAAAGAATGTTACAACAGCAGGAGCAACTAAGAGCTCTACAGGGACGGCAGGCTGCACTTCT
AGCTCTGCAACATAAAGCAGAGCAAGCTATTGCAGTGATGGATGATTCTGTTGTTGCAGAAACTGCAGGTAGCTTATCTGGCGTCAGTAT
CACATCTGAACTAAATGAAGAATTGAATGACTTAATTCAGCGTTTTCATAATCAGCTTCGTGATTCTCAGCCTCCAGCTGTTCCAGACAA
TAGAAGACAGGCAGAAAGTCTTTCATTAACTAGGGAGGTTTCCCAGAGCAGGAAACCATCAGCTTCAGAACGTTTACCTGATGAGAAAGT
CGAACTTTTTAGCAAAATGAGAGTGCTACAGGAAAAGAAACAAAAAATGGACAAATTGCTTGGAGAACTTCATACACTTCGAGATCAGCA
TCTTAACAATTCATCATCCTCTCCACAAAGGAGTGTCGATCAGAGAAGTACTTCAGCTCCCTCTGCTTCTGTAGGCTTGGCACCGGTTGT
CAATGGAGAATCCAATAGCCTCACATCATCTGTTCCTTATCCTACTGCTTCTCTAGTATCTCAGAATGAGAGTGAAAACGAAGGCCACCT
CAATCCATCTGAAAAACTCCAGAAGTTAAATGAAGTTCGAAAGAGATTGAATGAGCTAAGAGAATTAGTTCATTATTATGAACAAACGTC
AGACATGATGACAGATGCTGTGAATGAAAACAGGAAAGATGAAGAAACTGAAGAGTCAGAATATGATTCTGAGCATGAAAATTCCGAGCC
TGTTACTAACATTCGAAATCCACAAGTAGCTTCCACTTGGAATGAAGTAAATAGTCATAGTAATGCACAGTGTGTTTCTAATAATAGAGA
TGGGCGAACAGTTAATTCTAATTGTGAAATTAACAACAGATCTGCTGCCAACATAAGGGCTCTAAACATGCCTCCTTCTTTAGATTGTCG
ATATAATAGAGAAGGGGAACAGGAGATTCATGTTGCACAAGGTGAAGATGATGAGGAGGAGGAGGAAGAAGCAGAAGAGGAGGGAGTCAG
TGGAGCTTCATTATCTAGTCACAGGAGCAGTCTGGTTGATGAGCATCCAGAAGATGCTGAATTTGAACAGAAGATCAACCGACTTATGGC
TGCAAAACAGAAACTTAGACAGTTACAAGATCTTGTTGCTATGGTACAGGATGATGATGCAGCTCAAGGAGTTATCTCTGCCAGTGCATC
AAATTTGGATGATTTCTACCCAGCAGAAGAAGACACCAAGCAAAATTCAAATAACACTAGAGGAAATGCCAATAAAACACAGAAAGATAC
TGGAGTAAATGAAAAGGCAAGAGAGAAATTTTATGAGGCTAAACTACAGCAGCAACAGAGAGAGCTAAAACAATTGCAGGAAGAAAGAAA
GAAACTGATTGACATTCAGGAGAAAATTCAAGCATTGCAAACGGCATGCCCTGACTTACAGCTGTCAGCTGCTAGTGTGGGTAACTGTCC
CACCAAAAAATATATGCCAGCTGTTACTTCAACCCCAACTGTTAATCAACACGAGACCAGTACAAGCAAATCTGTTTTTGAGCCTGAAGA
TTCTTCAATAGTAGATAATGAGTTGTGGTCAGAAATGAGAAGACATGAAATGTTGAGGGAGGAGCTGCGACAGAGAAGAAAGCAGCTTGA
AGCTCTGATGGCTGAACATCAGAGGAGGCAAGGTCTAGCTGAAACTGCATCTCCAGTGGCTGTGTCATTGAGAAGTGATGGATCTGAGAA
CCTATGTACTCCTCAGCAAAGTAGAACAGAAAAAACGATGGCAACTTGGGGAGGGTCTACCCAGTGTGCACTAGATGAAGAAGGAGATGA
AGACGGTTACCTTTCTGAAGGAATTGTTCGGACAGATGAAGAGGAGGAAGAAGAGCAAGATGCCAGTTCCAATGATAACTTTTCTGTGTG
TCCTTCTAACAGTGTGAATCATAACTCCTACAATGGAAAGGAAACTAAAAATAGGTGGAAGAACAATTGCCCTTTTTCGGCAGATGAAAA
TTATCGTCCTTTAGCCAAGACAAGGCAACAGAATATCAGCATGCAACGGCAAGAAAACCTTCGTTGGGTGTCAGAGCTCTCTTACGTAGA
AGAGAAAGAACAATGGCAAGAACAAATCAATCAGCTAAAGAAACAGCTTGATTTTAGTGTCAGTATTTGTCAGACTTTGATGCAAGACCA
GCAGACTCTATCTTGTCTGCTACAAACTCTTCTCACGGGTCCTTACAGTGTTATGCCCAGCAATGTTGCATCTCCTCAAGTACACTTCAT
AATGCACCAGTTGAACCAGTGCTATACTCAGCTAACATGGCAACAGAATAATGTTCAGAGGTTGAAACAAATGCTAAATGAACTTATGCG
CCAGCAAAATCAGCATCCAGAAAAACCTGGAGGCAAGGAAAGAGGCAGTAGTGCATCGCACCCTCCTTCTCCCAGTTTATTTTGTCCTTT
CAGCTTTCCAACACAGCCTGTAAATCTCTTCAATATACCTGGATTTACTAACTTTTCATCATTTGCACCAGGTATGAATTTCAGCCCTTT
ATTTCCTTCTAATTTTGGAGATTTTTCTCAGAATATCTCTACACCCAGTGAACAGCAGCAACCCTTAGCCCAGAATTCTTCAGGAAAAAC
AGAATATATGGCTTTTCCAAAACCTTTTGAAAGCAGTTCCTCTATTGGAGCAGAGAAACCAAGGAATAAAAAACTGCCTGAAGAGGAGGT
GGAAAGCAGTAGGACACCATGGTTATATGAACAAGAAGGTGAAGTAGAGAAACCATTTATCAAGACTGGATTTTCAGTGTCTGTAGAAAA
ATCTACAAGTAGTAACCGCAAAAATCAATTAGATACAAACGGAAGAAGACGCCAGTTTGATGAAGAATCACTGGAAAGCTTTAGCAGTAT
GCCTGATCCAGTAGATCCAACAACAGTGACTAAAACATTCAAGACAAGAAAAGCGTCTGCACAGGCCAGCCTGGCATCTAAAGATAAAAC
TCCCAAGTCAAAAAGTAAGAAGAGGAATTCTACTCAGCTGAAAAGCAGAGTTAAAAACATCAGGTATGAAAGTGCCAGTATGTCTAGCAC
ATGTGAACCTTGCAAAAGTAGGAACAGACATTCAGCCCAGACTGAAGAGCCTGTTCAAGCAAAAGTATTCAGCAGAAAGAATCATGAGCA
ACTGGAAAAAATAATAAAATGTAATAGGTCTACAGAAATATCTTCAGAAACTGGGAGTGATTTTTCCATGTTTGAAGCTTTGCGAGATAC
TATTTATTCTGAAGTAGCTACATTAATTTCTCAAAATGAATCTCGTCCACATTTTCTTATTGAACTCTTCCATGAGCTGCAGCTACTAAA
CACAGACTACTTGAGACAGAGGGCTTTATATGCATTGCAGGACATAGTATCCAGACATATTTCTGAGAGCCATGAAAAAGGAGAAAATGT
AAAGTCAGTAAACTCTGGTACTTGGATAGCATCAAACTCAGAACTTACTCCTAGTGAGAGCCTTGCTACTACTGATGATGAAACTTTTGA
GAAGAACTTTGAAAGAGAAACCCATAAAATAAGTGAGCAAAATGATGCTGATAATGCTAGTGTCCTGTCTGTATCATCAAATTTTGAGCC
TTTTGCAACAGATGATCTAGGTAACACCGTGATTCACTTAGATCAAGCATTAGCCAGAATGAGAGAATATGAGCGTATGAAGACTGAGGC
TGAAAGTAACTCAAATATGAGATGCACCTGCAGGATTATTGAGGATGGAGATGGTGCTGGTGCAGGTACTACAGTTAATAATTTAGAAGA
AACTCCCGTTATTGAAAATCGTAGTTCACAACAACCTGTAAGTGAAGTTTCTACCATCCCATGTCCTAGAATTGATACTCAGCAGCTGGA
CCGGCAAATTAAAGCAATTATGAAAGAAGTCATTCCTTTTTTGAAGGAGGATCCAAAGTGGGAATTCCCTCGGAAGAACTTGGTTCTTGG
AAAAACTCTAGGAGAAGGCGAATTTGGAAAAGTGGTCAAGGCAACGGCCTTCCATCTGAAAGGCAGAGCAGGGTACACCACGGTGGCCGT
GAAGATGCTGAAAGAGAACGCCTCCCCGAGTGAGCTGCGAGACCTGCTGTCAGAGTTCAACGTCCTGAAGCAGGTCAACCACCCACATGT
CATCAAATTGTATGGGGCCTGCAGCCAGGATGGCCCGCTCCTCCTCATCGTGGAGTACGCCAAATACGGCTCCCTGCGGGGCTTCCTCCG
CGAGAGCCGCAAAGTGGGGCCTGGCTACCTGGGCAGTGGAGGCAGCCGCAACTCCAGCTCCCTGGACCACCCGGATGAGCGGGCCCTCAC
CATGGGCGACCTCATCTCATTTGCCTGGCAGATCTCACAGGGGATGCAGTATCTGGCCGAGATGAAGCTCGTTCATCGGGACTTGGCAGC
CAGAAACATCCTGGTAGCTGAGGGGCGGAAGATGAAGATTTCGGATTTCGGCTTGTCCCGAGATGTTTATGAAGAGGATTCCTACGTGAA
GAGGAGCCAGGGTCGGATTCCAGTTAAATGGATGGCAATTGAATCCCTTTTTGATCATATCTACACCACGCAAAGTGATGTATGGTCTTT
TGGTGTCCTGCTGTGGGAGATCGTGACCCTAGGGGGAAACCCCTATCCTGGGATTCCTCCTGAGCGGCTCTTCAACCTTCTGAAGACCGG
CCACCGGATGGAGAGGCCAGACAACTGCAGCGAGGAGATGTACCGCCTGATGCTGCAATGCTGGAAGCAGGAGCCGGACAAAAGGCCGGT
GTTTGCGGACATCAGCAAAGACCTGGAGAAGATGATGGTTAAGAGGAGAGACTACTTGGACCTTGCGGCGTCCACTCCATCTGACTCCCT
GATTTATGACGACGGCCTCTCAGAGGAGGAGACACCGCTGGTGGACTGTAATAATGCCCCCCTCCCTCGAGCCCTCCCTTCCACATGGAT
TGAAAACAAACTCTATGGCATGTCAGACCCGAACTGGCCTGGAGAGAGTCCTGTACCACTCACGAGAGCTGATGGCACTAACACTGGGTT
TCCAAGATATCCAAATGATAGTGTATATGCTAACTGGATGCTTTCACCCTCAGCGGCAAAATTAATGGACACGTTTGATAGTTAACATTT
CTTTGTGAAAGGTAATGGACTCACAAGGGGAAGAAACATGCTGAGAATGGAAAGTCTACCGGCCCTTTCTTTGTGAACGTCACATTGGCC
GAGCCGTGTTCAGTTCCCAGGTGGCAGACTCGTTTTTGGTAGTTTGTTTTAACTTCCAAGGTGGTTTTACTTCTGATAGCCGGTGATTTT
CCCTCCTAGCAGACATGCCACACCGGGTAAGAGCTCTGAGTCTTAGTGGTTAAGCATTCCTTTCTCTTCAGTGCCCAGCAGCACCCAGTG
TTGGTCTGTGTCCATCAGTGACCACCAACATTCTGTGTTCACATGTGTGGGTCCAACACTTACTACCTGGTGTATGAAATTGGACCTGAA
CTGTTGGATTTTTCTAGTTGCCGCCAAACAAGGCAAAAAAATTTAAACATGAAGCACACACACAAAAAAGGCAGTAGGAAAAATGCTGGC
CCTGATGACCTGTCCTTATTCAGAATGAGAGACTGCGGGGGGGGCCTGGGGGTAGTGTCAATGCCCCTCCAGGGCTGGAGGGGAAGAGGG
GCCCCGAGGATGGGCCTGGGCTCAGCATTCGAGATCTTGAGAATGATTTTTTTTAAATCATGCAACCTTTCCTTAGGAAGACATTTGGTT
TTCATCATGATTAAGATGATTCCTAGATTTAGCACAATGGAGAGATTCCATGCCATCTTTACTATGTGGATGGTGGTATCAGGGAAGAGG
GCTCACAAGACACATTTGTCCCCCGGGCCCACCACATCATCCTCACGTGTTCGGTACTGAGCAGCCACTACCCCTGATGAGAACAGTATG
AAGAAAGGGGGCTGTTGGAGTCCCAGAATTGCTGACAGCAGAGGCTTTGCTGCTGTGAATCCCACCTGCCACCAGCCTGCAGCACACCCC
ACAGCCAAGTAGAGGCGAAAGCAGTGGCTCATCCTACCTGTTAGGAGCAGGTAGGGCTTGTACTCACTTTAATTTGAATCTTATCAACTT
ACTCATAAAGGGACAGGCTAGCTAGCTGTGTTAGAAGTAGCAATGACAATGACCAAGGACTGCTACACCTCTGATTACAATTCTGATGTG
AAAAAGATGGTGTTTGGCTCTTATAGAGCCTGTGTGAAAGGCCCATGGATCAGCTCTTCCTGTGTTTGTAATTTAATGCTGCTACAAGAT
GTTTCTGTTTCTTAGATTCTGACCATGACTCATAAGCTTCTTGTCATTCTTCATTGCTTGTTTGTGGTCACAGATGCACAACACTCCTCC
AGTCTTGTGGGGGCAGCTTTTGGGAAGTCTCAGCAGCTCTTCTGGCTGTGTTGTCAGCACTGTAACTTCGCAGAAAAGAGTCGGATTACC
AAAACACTGCCTGCTCTTCAGACTTAAAGCACTGATAGGACTTAAAATAGTCTCATTCAAATACTGTATTTTATATAGGCATTTCACAAA
AACAGCAAAATTGTGGCATTTTGTGAGGCCAAGGCTTGGATGCGTGTGTAATAGAGCCTTGTGGTGTGTGCGCACACACCCAGAGGGAGA
GTTTGAAAAATGCTTATTGGACACGTAACCTGGCTCTAATTTGGGCTGTTTTTCAGATACACTGTGATAAGTTCTTTTACAAATATCTAT
AGACATGGTAAACTTTTGGTTTTCAGATATGCTTAATGATAGTCTTACTAAATGCAGAAATAAGAATAAACTTTCTCAAATTATTAAAAA
TGCCTACACAGTAAGTGTGAATTGCTGCAACAGGTTTGTTCTCAGGAGGGTAAGAACTCCAGGTCTAAACAGCTGACCCAGTGATGGGGA
ATTTATCCTTGACCAATTTATCCTTGACCAATAACCTAATTGTCTATTCCTGAGTTATAAAAGTCCCCATCCTTATTAGCTCTACTGGAA
TTTTCATACACGTAAATGCAGAAGTTACTAAGTATTAAGTATTACTGAGTATTAAGTAGTAATCTGTCAGTTATTAAAATTTGTAAAATC
TATTTATGAAAGGTCATTAAACCAGATCATGTTCCTTTTTTTGTAATCAAGGTGACTAAGAAAATCAGTTGTGTAAATAAAATCATGTAT

>63341_63341_10_PCM1-RET_PCM1_chr8_17851129_ENST00000325083_RET_chr10_43612030_ENST00000355710_length(amino acids)=2011AA_BP=1609
MATGGGPFEDGMNDQDLPNWSNENVDDRLNNMDWGAQQKKANRSSEKNKKKFGVESDKRVTNDISPESSPGVGRRRTKTPHTFPHSRYMS
QMSVPEQAELEKLKQRINFSDLDQRSIGSDSQGRATAANNKRQLSENRKPFNFLPMQINTNKSKDASTNPPNRETIGSAQCKELFASALS
NDLLQNCQVSEEDGRGEPAMESSQIVSRLVQIRDYITKASSMREDLVEKNERSANVERLTHLIDHLKEQEKSYMKFLKKILARDPQQEPM
EEIENLKKQHDLLKRMLQQQEQLRALQGRQAALLALQHKAEQAIAVMDDSVVAETAGSLSGVSITSELNEELNDLIQRFHNQLRDSQPPA
VPDNRRQAESLSLTREVSQSRKPSASERLPDEKVELFSKMRVLQEKKQKMDKLLGELHTLRDQHLNNSSSSPQRSVDQRSTSAPSASVGL
APVVNGESNSLTSSVPYPTASLVSQNESENEGHLNPSEKLQKLNEVRKRLNELRELVHYYEQTSDMMTDAVNENRKDEETEESEYDSEHE
NSEPVTNIRNPQVASTWNEVNSHSNAQCVSNNRDGRTVNSNCEINNRSAANIRALNMPPSLDCRYNREGEQEIHVAQGEDDEEEEEEAEE
EGVSGASLSSHRSSLVDEHPEDAEFEQKINRLMAAKQKLRQLQDLVAMVQDDDAAQGVISASASNLDDFYPAEEDTKQNSNNTRGNANKT
QKDTGVNEKAREKFYEAKLQQQQRELKQLQEERKKLIDIQEKIQALQTACPDLQLSAASVGNCPTKKYMPAVTSTPTVNQHETSTSKSVF
EPEDSSIVDNELWSEMRRHEMLREELRQRRKQLEALMAEHQRRQGLAETASPVAVSLRSDGSENLCTPQQSRTEKTMATWGGSTQCALDE
EGDEDGYLSEGIVRTDEEEEEEQDASSNDNFSVCPSNSVNHNSYNGKETKNRWKNNCPFSADENYRPLAKTRQQNISMQRQENLRWVSEL
SYVEEKEQWQEQINQLKKQLDFSVSICQTLMQDQQTLSCLLQTLLTGPYSVMPSNVASPQVHFIMHQLNQCYTQLTWQQNNVQRLKQMLN
ELMRQQNQHPEKPGGKERGSSASHPPSPSLFCPFSFPTQPVNLFNIPGFTNFSSFAPGMNFSPLFPSNFGDFSQNISTPSEQQQPLAQNS
SGKTEYMAFPKPFESSSSIGAEKPRNKKLPEEEVESSRTPWLYEQEGEVEKPFIKTGFSVSVEKSTSSNRKNQLDTNGRRRQFDEESLES
FSSMPDPVDPTTVTKTFKTRKASAQASLASKDKTPKSKSKKRNSTQLKSRVKNIRYESASMSSTCEPCKSRNRHSAQTEEPVQAKVFSRK
NHEQLEKIIKCNRSTEISSETGSDFSMFEALRDTIYSEVATLISQNESRPHFLIELFHELQLLNTDYLRQRALYALQDIVSRHISESHEK
GENVKSVNSGTWIASNSELTPSESLATTDDETFEKNFERETHKISEQNDADNASVLSVSSNFEPFATDDLGNTVIHLDQALARMREYERM
KTEAESNSNMRCTCRIIEDGDGAGAGTTVNNLEETPVIENRSSQQPVSEVSTIPCPRIDTQQLDRQIKAIMKEVIPFLKEDPKWEFPRKN
LVLGKTLGEGEFGKVVKATAFHLKGRAGYTTVAVKMLKENASPSELRDLLSEFNVLKQVNHPHVIKLYGACSQDGPLLLIVEYAKYGSLR
GFLRESRKVGPGYLGSGGSRNSSSLDHPDERALTMGDLISFAWQISQGMQYLAEMKLVHRDLAARNILVAEGRKMKISDFGLSRDVYEED
SYVKRSQGRIPVKWMAIESLFDHIYTTQSDVWSFGVLLWEIVTLGGNPYPGIPPERLFNLLKTGHRMERPDNCSEEMYRLMLQCWKQEPD
KRPVFADISKDLEKMMVKRRDYLDLAASTPSDSLIYDDGLSEEETPLVDCNNAPLPRALPSTWIENKLYGMSDPNWPGESPVPLTRADGT

--------------------------------------------------------------
>63341_63341_11_PCM1-RET_PCM1_chr8_17851129_ENST00000327578_RET_chr10_43612030_ENST00000340058_length(transcript)=2879nt_BP=1046nt
GAAAAGCGTCTGCACAGGCCAGCCTGGCATCTAAAGATAAAACTCCCAAGTCAAAAAGTAAGAAGAGGAATTCTACTCAGCTGAAAAGCA
GAGTTAAAAACATCAGGTATGAAAGTGCCAGTATGTCTAGCACATGTGAACCTTGCAAAAGTAGGAACAGACATTCAGCCCAGACTGAAG
AGCCTGTTCAAGCAAAAGTATTCAGCAGAAAGAATCATGAGCAACTGGAAAAAATAATAAAATGTAATAGGTCTACAGAAATATCTTCAG
CACATGCTAGGAGAATACTACAGCAGTCTAACAGAAATGCATGCAATGAAGCGCCAGAAACTGGGAGTGATTTTTCCATGTTTGAAGCTT
TGCGAGATACTATTTATTCTGAAGTAGCTACATTAATTTCTCAAAATGAATCTCGTCCACATTTTCTTATTGAACTCTTCCATGAGCTGC
AGCTACTAAACACAGACTACTTGAGACAGAGGGCTTTATATGCATTGCAGGACATAGTATCCAGACATATTTCTGAGAGCCATGAAAAAG
GAGAAAATGTAAAGTCAGTAAACTCTGGTACTTGGATAGCATCAAACTCAGAACTTACTCCTAGTGAGAGCCTTGCTACTACTGATGATG
AAACTTTTGAGAAGAACTTTGAAAGAGAAACCCATAAAATAAGTGAGCAAAATGATGCTGATAATGCTAGTGTCCTGTCTGTATCATCAA
ATTTTGAGCCTTTTGCAACAGATGATCTAGGTAACACCGTGATTCACTTAGATCAAGCATTAGCCAGAATGAGAGAATATGAGCGTATGA
AGACTGAGGCTGAAAGTAACTCAAATATGAGATGCACCTGCAGGATTATTGAGGATGGAGATGGTGCTGGTGCAGGTACTACAGTTAATA
ATTTAGAAGAAACTCCCGTTATTGAAAATCGTAGTTCACAACAACCTGTAAGTGAAGTTTCTACCATCCCATGTCCTAGAATTGATACTC
AGCAGCTGGACCGGCAAATTAAAGCAATTATGAAAGAAGTCATTCCTTTTTTGAAGGAGGATCCAAAGTGGGAATTCCCTCGGAAGAACT
TGGTTCTTGGAAAAACTCTAGGAGAAGGCGAATTTGGAAAAGTGGTCAAGGCAACGGCCTTCCATCTGAAAGGCAGAGCAGGGTACACCA
CGGTGGCCGTGAAGATGCTGAAAGAGAACGCCTCCCCGAGTGAGCTGCGAGACCTGCTGTCAGAGTTCAACGTCCTGAAGCAGGTCAACC
ACCCACATGTCATCAAATTGTATGGGGCCTGCAGCCAGGATGGCCCGCTCCTCCTCATCGTGGAGTACGCCAAATACGGCTCCCTGCGGG
GCTTCCTCCGCGAGAGCCGCAAAGTGGGGCCTGGCTACCTGGGCAGTGGAGGCAGCCGCAACTCCAGCTCCCTGGACCACCCGGATGAGC
GGGCCCTCACCATGGGCGACCTCATCTCATTTGCCTGGCAGATCTCACAGGGGATGCAGTATCTGGCCGAGATGAAGCTCGTTCATCGGG
ACTTGGCAGCCAGAAACATCCTGGTAGCTGAGGGGCGGAAGATGAAGATTTCGGATTTCGGCTTGTCCCGAGATGTTTATGAAGAGGATT
CCTACGTGAAGAGGAGCCAGGGTCGGATTCCAGTTAAATGGATGGCAATTGAATCCCTTTTTGATCATATCTACACCACGCAAAGTGATG
TATGGTCTTTTGGTGTCCTGCTGTGGGAGATCGTGACCCTAGGGGGAAACCCCTATCCTGGGATTCCTCCTGAGCGGCTCTTCAACCTTC
TGAAGACCGGCCACCGGATGGAGAGGCCAGACAACTGCAGCGAGGAGATGTACCGCCTGATGCTGCAATGCTGGAAGCAGGAGCCGGACA
AAAGGCCGGTGTTTGCGGACATCAGCAAAGACCTGGAGAAGATGATGGTTAAGAGGAGAGACTACTTGGACCTTGCGGCGTCCACTCCAT
CTGACTCCCTGATTTATGACGACGGCCTCTCAGAGGAGGAGACACCGCTGGTGGACTGTAATAATGCCCCCCTCCCTCGAGCCCTCCCTT
CCACATGGATTGAAAACAAACTCTATGGTAGAATTTCCCATGCATTTACTAGATTCTAGCACCGCTGTCCCCTTTGCACTATCCTTCCTC
TCTGTGATGCTTTTTAAAAATGTTTCTGGTCTGAACAAAACCAAAGTCTGCTCTGAACCTTTTTATTTGTAAATGTCTGACTTTGCATCC
AGTTTACATTTAGGCATTATTGCAACTATGTTTTTCTAAAAGGATGTGAAAATAAGTGTAATTACCACATTGCCCAGCAACTTAGGATGG
TAGAGGAAAAAACAGATCAGGGCGGAACTCTCAGGGGAGACCAAGAACAGGTTGAATAAGGCGCTTCTGGGGTGGGAATCAAGTCATAGT
ACTTCTACTTTAACTAAGTGGATAAATATACAAATCTGGGGAGGTATTCAGTTGAGAAAGGAGCCACCAGCACCACTCAGCCTGCACTGG
GAGCACAGCCAGGTTCCCCCAGACCCCTCCTGGGCAGGCAGGTGCCTCTCAGAGGCCACCCGGCACTGGCGAGCAGCCACTGGCCAAGCC
TCAGCCCCAGTCCCAGCCACATGTCCTCCATCAGGGGTAGCGAGGTTGCAGGAGCTGGCTGGCCCTGGGAGGACGCACCCCCACTGCTGT
TTTCACATCCTTTCCCTTACCCACCTTCAGGACGGTTGTCACTTATGAAGTCAGTGCTAAAGCTGGAGCAGTTGCTTTTTGAAAGAACAT

>63341_63341_11_PCM1-RET_PCM1_chr8_17851129_ENST00000327578_RET_chr10_43612030_ENST00000340058_length(amino acids)=701AA_BP=341
MASKDKTPKSKSKKRNSTQLKSRVKNIRYESASMSSTCEPCKSRNRHSAQTEEPVQAKVFSRKNHEQLEKIIKCNRSTEISSAHARRILQ
QSNRNACNEAPETGSDFSMFEALRDTIYSEVATLISQNESRPHFLIELFHELQLLNTDYLRQRALYALQDIVSRHISESHEKGENVKSVN
SGTWIASNSELTPSESLATTDDETFEKNFERETHKISEQNDADNASVLSVSSNFEPFATDDLGNTVIHLDQALARMREYERMKTEAESNS
NMRCTCRIIEDGDGAGAGTTVNNLEETPVIENRSSQQPVSEVSTIPCPRIDTQQLDRQIKAIMKEVIPFLKEDPKWEFPRKNLVLGKTLG
EGEFGKVVKATAFHLKGRAGYTTVAVKMLKENASPSELRDLLSEFNVLKQVNHPHVIKLYGACSQDGPLLLIVEYAKYGSLRGFLRESRK
VGPGYLGSGGSRNSSSLDHPDERALTMGDLISFAWQISQGMQYLAEMKLVHRDLAARNILVAEGRKMKISDFGLSRDVYEEDSYVKRSQG
RIPVKWMAIESLFDHIYTTQSDVWSFGVLLWEIVTLGGNPYPGIPPERLFNLLKTGHRMERPDNCSEEMYRLMLQCWKQEPDKRPVFADI

--------------------------------------------------------------
>63341_63341_12_PCM1-RET_PCM1_chr8_17851129_ENST00000327578_RET_chr10_43612030_ENST00000355710_length(transcript)=4337nt_BP=1046nt
GAAAAGCGTCTGCACAGGCCAGCCTGGCATCTAAAGATAAAACTCCCAAGTCAAAAAGTAAGAAGAGGAATTCTACTCAGCTGAAAAGCA
GAGTTAAAAACATCAGGTATGAAAGTGCCAGTATGTCTAGCACATGTGAACCTTGCAAAAGTAGGAACAGACATTCAGCCCAGACTGAAG
AGCCTGTTCAAGCAAAAGTATTCAGCAGAAAGAATCATGAGCAACTGGAAAAAATAATAAAATGTAATAGGTCTACAGAAATATCTTCAG
CACATGCTAGGAGAATACTACAGCAGTCTAACAGAAATGCATGCAATGAAGCGCCAGAAACTGGGAGTGATTTTTCCATGTTTGAAGCTT
TGCGAGATACTATTTATTCTGAAGTAGCTACATTAATTTCTCAAAATGAATCTCGTCCACATTTTCTTATTGAACTCTTCCATGAGCTGC
AGCTACTAAACACAGACTACTTGAGACAGAGGGCTTTATATGCATTGCAGGACATAGTATCCAGACATATTTCTGAGAGCCATGAAAAAG
GAGAAAATGTAAAGTCAGTAAACTCTGGTACTTGGATAGCATCAAACTCAGAACTTACTCCTAGTGAGAGCCTTGCTACTACTGATGATG
AAACTTTTGAGAAGAACTTTGAAAGAGAAACCCATAAAATAAGTGAGCAAAATGATGCTGATAATGCTAGTGTCCTGTCTGTATCATCAA
ATTTTGAGCCTTTTGCAACAGATGATCTAGGTAACACCGTGATTCACTTAGATCAAGCATTAGCCAGAATGAGAGAATATGAGCGTATGA
AGACTGAGGCTGAAAGTAACTCAAATATGAGATGCACCTGCAGGATTATTGAGGATGGAGATGGTGCTGGTGCAGGTACTACAGTTAATA
ATTTAGAAGAAACTCCCGTTATTGAAAATCGTAGTTCACAACAACCTGTAAGTGAAGTTTCTACCATCCCATGTCCTAGAATTGATACTC
AGCAGCTGGACCGGCAAATTAAAGCAATTATGAAAGAAGTCATTCCTTTTTTGAAGGAGGATCCAAAGTGGGAATTCCCTCGGAAGAACT
TGGTTCTTGGAAAAACTCTAGGAGAAGGCGAATTTGGAAAAGTGGTCAAGGCAACGGCCTTCCATCTGAAAGGCAGAGCAGGGTACACCA
CGGTGGCCGTGAAGATGCTGAAAGAGAACGCCTCCCCGAGTGAGCTGCGAGACCTGCTGTCAGAGTTCAACGTCCTGAAGCAGGTCAACC
ACCCACATGTCATCAAATTGTATGGGGCCTGCAGCCAGGATGGCCCGCTCCTCCTCATCGTGGAGTACGCCAAATACGGCTCCCTGCGGG
GCTTCCTCCGCGAGAGCCGCAAAGTGGGGCCTGGCTACCTGGGCAGTGGAGGCAGCCGCAACTCCAGCTCCCTGGACCACCCGGATGAGC
GGGCCCTCACCATGGGCGACCTCATCTCATTTGCCTGGCAGATCTCACAGGGGATGCAGTATCTGGCCGAGATGAAGCTCGTTCATCGGG
ACTTGGCAGCCAGAAACATCCTGGTAGCTGAGGGGCGGAAGATGAAGATTTCGGATTTCGGCTTGTCCCGAGATGTTTATGAAGAGGATT
CCTACGTGAAGAGGAGCCAGGGTCGGATTCCAGTTAAATGGATGGCAATTGAATCCCTTTTTGATCATATCTACACCACGCAAAGTGATG
TATGGTCTTTTGGTGTCCTGCTGTGGGAGATCGTGACCCTAGGGGGAAACCCCTATCCTGGGATTCCTCCTGAGCGGCTCTTCAACCTTC
TGAAGACCGGCCACCGGATGGAGAGGCCAGACAACTGCAGCGAGGAGATGTACCGCCTGATGCTGCAATGCTGGAAGCAGGAGCCGGACA
AAAGGCCGGTGTTTGCGGACATCAGCAAAGACCTGGAGAAGATGATGGTTAAGAGGAGAGACTACTTGGACCTTGCGGCGTCCACTCCAT
CTGACTCCCTGATTTATGACGACGGCCTCTCAGAGGAGGAGACACCGCTGGTGGACTGTAATAATGCCCCCCTCCCTCGAGCCCTCCCTT
CCACATGGATTGAAAACAAACTCTATGGCATGTCAGACCCGAACTGGCCTGGAGAGAGTCCTGTACCACTCACGAGAGCTGATGGCACTA
ACACTGGGTTTCCAAGATATCCAAATGATAGTGTATATGCTAACTGGATGCTTTCACCCTCAGCGGCAAAATTAATGGACACGTTTGATA
GTTAACATTTCTTTGTGAAAGGTAATGGACTCACAAGGGGAAGAAACATGCTGAGAATGGAAAGTCTACCGGCCCTTTCTTTGTGAACGT
CACATTGGCCGAGCCGTGTTCAGTTCCCAGGTGGCAGACTCGTTTTTGGTAGTTTGTTTTAACTTCCAAGGTGGTTTTACTTCTGATAGC
CGGTGATTTTCCCTCCTAGCAGACATGCCACACCGGGTAAGAGCTCTGAGTCTTAGTGGTTAAGCATTCCTTTCTCTTCAGTGCCCAGCA
GCACCCAGTGTTGGTCTGTGTCCATCAGTGACCACCAACATTCTGTGTTCACATGTGTGGGTCCAACACTTACTACCTGGTGTATGAAAT
TGGACCTGAACTGTTGGATTTTTCTAGTTGCCGCCAAACAAGGCAAAAAAATTTAAACATGAAGCACACACACAAAAAAGGCAGTAGGAA
AAATGCTGGCCCTGATGACCTGTCCTTATTCAGAATGAGAGACTGCGGGGGGGGCCTGGGGGTAGTGTCAATGCCCCTCCAGGGCTGGAG
GGGAAGAGGGGCCCCGAGGATGGGCCTGGGCTCAGCATTCGAGATCTTGAGAATGATTTTTTTTAAATCATGCAACCTTTCCTTAGGAAG
ACATTTGGTTTTCATCATGATTAAGATGATTCCTAGATTTAGCACAATGGAGAGATTCCATGCCATCTTTACTATGTGGATGGTGGTATC
AGGGAAGAGGGCTCACAAGACACATTTGTCCCCCGGGCCCACCACATCATCCTCACGTGTTCGGTACTGAGCAGCCACTACCCCTGATGA
GAACAGTATGAAGAAAGGGGGCTGTTGGAGTCCCAGAATTGCTGACAGCAGAGGCTTTGCTGCTGTGAATCCCACCTGCCACCAGCCTGC
AGCACACCCCACAGCCAAGTAGAGGCGAAAGCAGTGGCTCATCCTACCTGTTAGGAGCAGGTAGGGCTTGTACTCACTTTAATTTGAATC
TTATCAACTTACTCATAAAGGGACAGGCTAGCTAGCTGTGTTAGAAGTAGCAATGACAATGACCAAGGACTGCTACACCTCTGATTACAA
TTCTGATGTGAAAAAGATGGTGTTTGGCTCTTATAGAGCCTGTGTGAAAGGCCCATGGATCAGCTCTTCCTGTGTTTGTAATTTAATGCT
GCTACAAGATGTTTCTGTTTCTTAGATTCTGACCATGACTCATAAGCTTCTTGTCATTCTTCATTGCTTGTTTGTGGTCACAGATGCACA
ACACTCCTCCAGTCTTGTGGGGGCAGCTTTTGGGAAGTCTCAGCAGCTCTTCTGGCTGTGTTGTCAGCACTGTAACTTCGCAGAAAAGAG
TCGGATTACCAAAACACTGCCTGCTCTTCAGACTTAAAGCACTGATAGGACTTAAAATAGTCTCATTCAAATACTGTATTTTATATAGGC
ATTTCACAAAAACAGCAAAATTGTGGCATTTTGTGAGGCCAAGGCTTGGATGCGTGTGTAATAGAGCCTTGTGGTGTGTGCGCACACACC
CAGAGGGAGAGTTTGAAAAATGCTTATTGGACACGTAACCTGGCTCTAATTTGGGCTGTTTTTCAGATACACTGTGATAAGTTCTTTTAC
AAATATCTATAGACATGGTAAACTTTTGGTTTTCAGATATGCTTAATGATAGTCTTACTAAATGCAGAAATAAGAATAAACTTTCTCAAA
TTATTAAAAATGCCTACACAGTAAGTGTGAATTGCTGCAACAGGTTTGTTCTCAGGAGGGTAAGAACTCCAGGTCTAAACAGCTGACCCA
GTGATGGGGAATTTATCCTTGACCAATTTATCCTTGACCAATAACCTAATTGTCTATTCCTGAGTTATAAAAGTCCCCATCCTTATTAGC
TCTACTGGAATTTTCATACACGTAAATGCAGAAGTTACTAAGTATTAAGTATTACTGAGTATTAAGTAGTAATCTGTCAGTTATTAAAAT
TTGTAAAATCTATTTATGAAAGGTCATTAAACCAGATCATGTTCCTTTTTTTGTAATCAAGGTGACTAAGAAAATCAGTTGTGTAAATAA

>63341_63341_12_PCM1-RET_PCM1_chr8_17851129_ENST00000327578_RET_chr10_43612030_ENST00000355710_length(amino acids)=743AA_BP=341
MASKDKTPKSKSKKRNSTQLKSRVKNIRYESASMSSTCEPCKSRNRHSAQTEEPVQAKVFSRKNHEQLEKIIKCNRSTEISSAHARRILQ
QSNRNACNEAPETGSDFSMFEALRDTIYSEVATLISQNESRPHFLIELFHELQLLNTDYLRQRALYALQDIVSRHISESHEKGENVKSVN
SGTWIASNSELTPSESLATTDDETFEKNFERETHKISEQNDADNASVLSVSSNFEPFATDDLGNTVIHLDQALARMREYERMKTEAESNS
NMRCTCRIIEDGDGAGAGTTVNNLEETPVIENRSSQQPVSEVSTIPCPRIDTQQLDRQIKAIMKEVIPFLKEDPKWEFPRKNLVLGKTLG
EGEFGKVVKATAFHLKGRAGYTTVAVKMLKENASPSELRDLLSEFNVLKQVNHPHVIKLYGACSQDGPLLLIVEYAKYGSLRGFLRESRK
VGPGYLGSGGSRNSSSLDHPDERALTMGDLISFAWQISQGMQYLAEMKLVHRDLAARNILVAEGRKMKISDFGLSRDVYEEDSYVKRSQG
RIPVKWMAIESLFDHIYTTQSDVWSFGVLLWEIVTLGGNPYPGIPPERLFNLLKTGHRMERPDNCSEEMYRLMLQCWKQEPDKRPVFADI
SKDLEKMMVKRRDYLDLAASTPSDSLIYDDGLSEEETPLVDCNNAPLPRALPSTWIENKLYGMSDPNWPGESPVPLTRADGTNTGFPRYP

--------------------------------------------------------------
>63341_63341_13_PCM1-RET_PCM1_chr8_17851129_ENST00000519253_RET_chr10_43612030_ENST00000340058_length(transcript)=6887nt_BP=5054nt
GCTGCGTAGCTGAGGTCGAAAAGGCGGCCACTGGGGCCGAGGCAGCCAGGAAACGTGTGGGCCTCTCTGCTGCGGTCTCCGAGGGCCGAC
CGCTGCCGGCGGCGGGTCGTGGGGGCTGACTGTCGCTCTGCCTTTGACAGGAGAGGCTGCTTCTTGTAGAGGAAACAGCTTTGAAGTGTG
GAGCGGGAAAGGAGCAGTTTCTGAGCTGCAAAAACTAGTTTCTAAACAGAGAGTTAATTGTTAAATCCAGTATGGCCACAGGAGGAGGTC
CCTTTGAAGATGGCATGAATGATCAGGATTTACCAAACTGGAGTAATGAGAATGTTGATGACAGGCTCAACAATATGGATTGGGGTGCCC
AACAGAAGAAAGCAAATAGATCATCAGAAAAGAATAAGAAAAAGTTTGGTGTAGAAAGTGATAAAAGAGTAACCAATGATATTTCTCCGG
AGTCGTCACCAGGAGTTGGAAGGCGAAGAACAAAGACTCCACATACGTTCCCACACAGTAGATACATGAGTCAGATGTCTGTCCCAGAGC
AGGCAGAATTAGAGAAACTGAAACAGCGGATAAACTTCAGTGATTTAGATCAGAGAAGCATTGGAAGTGATTCCCAAGGTAGAGCAACAG
CTGCTAACAACAAACGTCAGCTTAGTGAAAACCGAAAGCCCTTCAACTTTTTGCCTATGCAGATTAATACTAACAAGAGCAAAGATGCAT
CTACAAACCCCCCAAACAGAGAAACGATTGGATCAGCACAGTGTAAAGAGTTGTTTGCTTCTGCTTTAAGTAATGACCTCTTGCAAAACT
GTCAGGTGTCTGAAGAAGATGGGAGGGGAGAACCTGCAATGGAGAGCAGCCAGATTGTAAGCAGGCTTGTTCAAATTCGCGATTATATTA
CTAAAGCTAGTTCCATGCGGGAAGATCTTGTAGAGAAAAATGAGAGATCTGCTAATGTTGAGCGCCTTACTCATCTAATAGATCACCTTA
AAGAACAAGAGAAGTCATATATGAAATTTCTTAAAAAAATCCTTGCCAGAGATCCTCAGCAGGAGCCTATGGAAGAGATAGAAAATTTGA
AGAAACAACATGATTTATTAAAAAGAATGTTACAACAGCAGGAGCAACTAAGAGCTCTACAGGGACGGCAGGCTGCACTTCTAGCTCTGC
AACATAAAGCAGAGCAAGCTATTGCAGTGATGGATGATTCTGTTGTTGCAGAAACTGCAGGTAGCTTATCTGGCGTCAGTATCACATCTG
AACTAAATGAAGAATTGAATGACTTAATTCAGCGTTTTCATAATCAGCTTCGTGATTCTCAGCCTCCAGCTGTTCCAGACAATAGAAGAC
AGGCAGAAAGTCTTTCATTAACTAGGGAGGTTTCCCAGAGCAGGAAACCATCAGCTTCAGAACGTTTACCTGATGAGAAAGTCGAACTTT
TTAGCAAAATGAGAGTGCTACAGGAAAAGAAACAAAAAATGGACAAATTGCTTGGAGAACTTCATACACTTCGAGATCAGCATCTTAACA
ATTCATCATCCTCTCCACAAAGGAGTGTCGATCAGAGAAGTACTTCAGCTCCCTCTGCTTCTGTAGGCTTGGCACCGGTTGTCAATGGAG
AATCCAATAGCCTCACATCATCTGTTCCTTATCCTACTGCTTCTCTAGTATCTCAGAATGAGAGTGAAAACGAAGGCCACCTCAATCCAT
CTGAAAAACTCCAGAAGTTAAATGAAGTTCGAAAGAGATTGAATGAGCTAAGAGAATTAGTTCATTATTATGAACAAACGTCAGACATGA
TGACAGATGCTGTGAATGAAAACAGGAAAGATGAAGAAACTGAAGAGTCAGAATATGATTCTGAGCATGAAAATTCCGAGCCTGTTACTA
ACATTCGAAATCCACAAGTAGCTTCCACTTGGAATGAAGTAAATAGTCATAGTAATGCACAGTGTGTTTCTAATAATAGAGATGGGCGAA
CAGTTAATTCTAATTGTGAAATTAACAACAGATCTGCTGCCAACATAAGGGCTCTAAACATGCCTCCTTCTTTAGATTGTCGATATAATA
GAGAAGGGGAACAGGAGATTCATGTTGCACAAGGTGAAGATGATGAGGAGGAGGAGGAAGAAGCAGAAGAGGAGGGAGTCAGTGGAGCTT
CATTATCTAGTCACAGGAGCAGTCTGGTTGATGAGCATCCAGAAGATGCTGAATTTGAACAGAAGATCAACCGACTTATGGCTGCAAAAC
AGAAACTTAGACAGTTACAAGATCTTGTTGCTATGGTACAGGATGATGATGCAGCTCAAGGAGTTATCTCTGCCAGTGCATCAAATTTGG
ATGATTTCTACCCAGCAGAAGAAGACACCAAGCAAAATTCAAATAACACTAGAGGAAATGCCAATAAAACACAGAAAGATACTGGAGTAA
ATGAAAAGGCAAGAGAGAAATTTTATGAGGCTAAACTACAGCAGCAACAGAGAGAGCTAAAACAATTGCAGGAAGAAAGAAAGAAACTGA
TTGACATTCAGGAGAAAATTCAAGCATTGCAAACGGCATGCCCTGACTTACAGCTGTCAGCTGCTAGTGTGGGTAACTGTCCCACCAAAA
AATATATGCCAGCTGTTACTTCAACCCCAACTGTTAATCAACACGAGACCAGTACAAGCAAATCTGTTTTTGAGCCTGAAGATTCTTCAA
TAGTAGATAATGAGTTGTGGTCAGAAATGAGAAGACATGAAATGTTGAGGGAGGAGCTGCGACAGAGAAGAAAGCAGCTTGAAGCTCTGA
TGGCTGAACATCAGAGGAGGCAAGGTCTAGCTGAAACTGCATCTCCAGTGGCTGTGTCATTGAGAAGTGATGGATCTGAGAACCTATGTA
CTCCTCAGCAAAGTAGAACAGAAAAAACGATGGCAACTTGGGGAGGGTCTACCCAGTGTGCACTAGATGAAGAAGGAGATGAAGACGGTT
ACCTTTCTGAAGGAATTGTTCGGACAGATGAAGAGGAGGAAGAAGAGCAAGATGCCAGTTCCAATGATAACTTTTCTGTGTGTCCTTCTA
ACAGTGTGAATCATAACTCCTACAATGGAAAGGAAACTAAAAATAGGTGGAAGAACAATTGCCCTTTTTCGGCAGATGAAAATTATCGTC
CTTTAGCCAAGACAAGGCAACAGAATATCAGCATGCAACGGCAAGAAAACCTTCGTTGGGTGTCAGAGCTCTCTTACGTAGAAGAGAAAG
AACAATGGCAAGAACAAATCAATCAGCTAAAGAAACAGCTTGATTTTAGTGTCAGTATTTGTCAGACTTTGATGCAAGACCAGCAGACTC
TATCTTGTCTGCTACAAACTCTTCTCACGGGTCCTTACAGTGTTATGCCCAGCAATGTTGCATCTCCTCAAGTACACTTCATAATGCACC
AGTTGAACCAGTGCTATACTCAGCTAACATGGCAACAGAATAATGTTCAGAGGTTGAAACAAATGCTAAATGAACTTATGCGCCAGCAAA
ATCAGCATCCAGAAAAACCTGGAGGCAAGGAAAGAGGCAGTAGTGCATCGCACCCTCCTTCTCCCAGTTTATTTTGTCCTTTCAGCTTTC
CAACACAGCCTGTAAATCTCTTCAATATACCTGGATTTACTAACTTTTCATCATTTGCACCAGGTATGAATTTCAGCCCTTTATTTCCTT
CTAATTTTGGAGATTTTTCTCAGAATATCTCTACACCCAGTGAACAGCAGCAACCCTTAGCCCAGAATTCTTCAGGAAAAACAGAATATA
TGGCTTTTCCAAAACCTTTTGAAAGCAGTTCCTCTATTGGAGCAGAGAAACCAAGGAATAAAAAACTGCCTGAAGAGGAGGTGGAAAGCA
GTAGGACACCATGGTTATATGAACAAGAAGGTGAAGTAGAGAAACCATTTATCAAGACTGGATTTTCAGTGTCTGTAGAAAAATCTACAA
GTAGTAACCGCAAAAATCAATTAGATACAAACGGAAGAAGACGCCAGTTTGATGAAGAATCACTGGAAAGCTTTAGCAGTATGCCTGATC
CAGTAGATCCAACAACAGTGACTAAAACATTCAAGACAAGAAAAGCGTCTGCACAGGCCAGCCTGGCATCTAAAGATAAAACTCCCAAGT
CAAAAAGTAAGAAGAGGAATTCTACTCAGCTGAAAAGCAGAGTTAAAAACATCAGGTATGAAAGTGCCAGTATGTCTAGCACATGTGAAC
CTTGCAAAAGTAGGAACAGACATTCAGCCCAGACTGAAGAGCCTGTTCAAGCAAAAGTATTCAGCAGAAAGAATCATGAGCAACTGGAAA
AAATAATAAAATGTAATAGGTCTACAGAAATATCTTCAGAAACTGGGAGTGATTTTTCCATGTTTGAAGCTTTGCGAGATACTATTTATT
CTGAAGTAGCTACATTAATTTCTCAAAATGAATCTCGTCCACATTTTCTTATTGAACTCTTCCATGAGCTGCAGCTACTAAACACAGACT
ACTTGAGACAGAGGGCTTTATATGCATTGCAGGACATAGTATCCAGACATATTTCTGAGAGCCATGAAAAAGGAGAAAATGTAAAGTCAG
TAAACTCTGGTACTTGGATAGCATCAAACTCAGAACTTACTCCTAGTGAGAGCCTTGCTACTACTGATGATGAAACTTTTGAGAAGAACT
TTGAAAGAGAAACCCATAAAATAAGTGAGCAAAATGATGCTGATAATGCTAGTGTCCTGTCTGTATCATCAAATTTTGAGCCTTTTGCAA
CAGATGATCTAGGTAACACCGTGATTCACTTAGATCAAGCATTAGCCAGAATGAGAGAATATGAGCGTATGAAGACTGAGGCTGAAAGTA
ACTCAAATATGAGATGCACCTGCAGGATTATTGAGGATGGAGATGGTGCTGGTGCAGAAACTCCCGTTATTGAAAATCGTAGTTCACAAC
AACCTGTAAGTGAAGTTTCTACCATCCCATGTCCTAGAATTGATACTCAGCAGCTGGACCGGCAAATTAAAGCAATTATGAAAGAAGTCA
TTCCTTTTTTGAAGGAGGATCCAAAGTGGGAATTCCCTCGGAAGAACTTGGTTCTTGGAAAAACTCTAGGAGAAGGCGAATTTGGAAAAG
TGGTCAAGGCAACGGCCTTCCATCTGAAAGGCAGAGCAGGGTACACCACGGTGGCCGTGAAGATGCTGAAAGAGAACGCCTCCCCGAGTG
AGCTGCGAGACCTGCTGTCAGAGTTCAACGTCCTGAAGCAGGTCAACCACCCACATGTCATCAAATTGTATGGGGCCTGCAGCCAGGATG
GCCCGCTCCTCCTCATCGTGGAGTACGCCAAATACGGCTCCCTGCGGGGCTTCCTCCGCGAGAGCCGCAAAGTGGGGCCTGGCTACCTGG
GCAGTGGAGGCAGCCGCAACTCCAGCTCCCTGGACCACCCGGATGAGCGGGCCCTCACCATGGGCGACCTCATCTCATTTGCCTGGCAGA
TCTCACAGGGGATGCAGTATCTGGCCGAGATGAAGCTCGTTCATCGGGACTTGGCAGCCAGAAACATCCTGGTAGCTGAGGGGCGGAAGA
TGAAGATTTCGGATTTCGGCTTGTCCCGAGATGTTTATGAAGAGGATTCCTACGTGAAGAGGAGCCAGGGTCGGATTCCAGTTAAATGGA
TGGCAATTGAATCCCTTTTTGATCATATCTACACCACGCAAAGTGATGTATGGTCTTTTGGTGTCCTGCTGTGGGAGATCGTGACCCTAG
GGGGAAACCCCTATCCTGGGATTCCTCCTGAGCGGCTCTTCAACCTTCTGAAGACCGGCCACCGGATGGAGAGGCCAGACAACTGCAGCG
AGGAGATGTACCGCCTGATGCTGCAATGCTGGAAGCAGGAGCCGGACAAAAGGCCGGTGTTTGCGGACATCAGCAAAGACCTGGAGAAGA
TGATGGTTAAGAGGAGAGACTACTTGGACCTTGCGGCGTCCACTCCATCTGACTCCCTGATTTATGACGACGGCCTCTCAGAGGAGGAGA
CACCGCTGGTGGACTGTAATAATGCCCCCCTCCCTCGAGCCCTCCCTTCCACATGGATTGAAAACAAACTCTATGGTAGAATTTCCCATG
CATTTACTAGATTCTAGCACCGCTGTCCCCTTTGCACTATCCTTCCTCTCTGTGATGCTTTTTAAAAATGTTTCTGGTCTGAACAAAACC
AAAGTCTGCTCTGAACCTTTTTATTTGTAAATGTCTGACTTTGCATCCAGTTTACATTTAGGCATTATTGCAACTATGTTTTTCTAAAAG
GATGTGAAAATAAGTGTAATTACCACATTGCCCAGCAACTTAGGATGGTAGAGGAAAAAACAGATCAGGGCGGAACTCTCAGGGGAGACC
AAGAACAGGTTGAATAAGGCGCTTCTGGGGTGGGAATCAAGTCATAGTACTTCTACTTTAACTAAGTGGATAAATATACAAATCTGGGGA
GGTATTCAGTTGAGAAAGGAGCCACCAGCACCACTCAGCCTGCACTGGGAGCACAGCCAGGTTCCCCCAGACCCCTCCTGGGCAGGCAGG
TGCCTCTCAGAGGCCACCCGGCACTGGCGAGCAGCCACTGGCCAAGCCTCAGCCCCAGTCCCAGCCACATGTCCTCCATCAGGGGTAGCG
AGGTTGCAGGAGCTGGCTGGCCCTGGGAGGACGCACCCCCACTGCTGTTTTCACATCCTTTCCCTTACCCACCTTCAGGACGGTTGTCAC
TTATGAAGTCAGTGCTAAAGCTGGAGCAGTTGCTTTTTGAAAGAACATGGTCTGTGGTGCTGTGGTCTTACAATGGACAGTAAATATGGT

>63341_63341_13_PCM1-RET_PCM1_chr8_17851129_ENST00000519253_RET_chr10_43612030_ENST00000340058_length(amino acids)=1961AA_BP=1601
MATGGGPFEDGMNDQDLPNWSNENVDDRLNNMDWGAQQKKANRSSEKNKKKFGVESDKRVTNDISPESSPGVGRRRTKTPHTFPHSRYMS
QMSVPEQAELEKLKQRINFSDLDQRSIGSDSQGRATAANNKRQLSENRKPFNFLPMQINTNKSKDASTNPPNRETIGSAQCKELFASALS
NDLLQNCQVSEEDGRGEPAMESSQIVSRLVQIRDYITKASSMREDLVEKNERSANVERLTHLIDHLKEQEKSYMKFLKKILARDPQQEPM
EEIENLKKQHDLLKRMLQQQEQLRALQGRQAALLALQHKAEQAIAVMDDSVVAETAGSLSGVSITSELNEELNDLIQRFHNQLRDSQPPA
VPDNRRQAESLSLTREVSQSRKPSASERLPDEKVELFSKMRVLQEKKQKMDKLLGELHTLRDQHLNNSSSSPQRSVDQRSTSAPSASVGL
APVVNGESNSLTSSVPYPTASLVSQNESENEGHLNPSEKLQKLNEVRKRLNELRELVHYYEQTSDMMTDAVNENRKDEETEESEYDSEHE
NSEPVTNIRNPQVASTWNEVNSHSNAQCVSNNRDGRTVNSNCEINNRSAANIRALNMPPSLDCRYNREGEQEIHVAQGEDDEEEEEEAEE
EGVSGASLSSHRSSLVDEHPEDAEFEQKINRLMAAKQKLRQLQDLVAMVQDDDAAQGVISASASNLDDFYPAEEDTKQNSNNTRGNANKT
QKDTGVNEKAREKFYEAKLQQQQRELKQLQEERKKLIDIQEKIQALQTACPDLQLSAASVGNCPTKKYMPAVTSTPTVNQHETSTSKSVF
EPEDSSIVDNELWSEMRRHEMLREELRQRRKQLEALMAEHQRRQGLAETASPVAVSLRSDGSENLCTPQQSRTEKTMATWGGSTQCALDE
EGDEDGYLSEGIVRTDEEEEEEQDASSNDNFSVCPSNSVNHNSYNGKETKNRWKNNCPFSADENYRPLAKTRQQNISMQRQENLRWVSEL
SYVEEKEQWQEQINQLKKQLDFSVSICQTLMQDQQTLSCLLQTLLTGPYSVMPSNVASPQVHFIMHQLNQCYTQLTWQQNNVQRLKQMLN
ELMRQQNQHPEKPGGKERGSSASHPPSPSLFCPFSFPTQPVNLFNIPGFTNFSSFAPGMNFSPLFPSNFGDFSQNISTPSEQQQPLAQNS
SGKTEYMAFPKPFESSSSIGAEKPRNKKLPEEEVESSRTPWLYEQEGEVEKPFIKTGFSVSVEKSTSSNRKNQLDTNGRRRQFDEESLES
FSSMPDPVDPTTVTKTFKTRKASAQASLASKDKTPKSKSKKRNSTQLKSRVKNIRYESASMSSTCEPCKSRNRHSAQTEEPVQAKVFSRK
NHEQLEKIIKCNRSTEISSETGSDFSMFEALRDTIYSEVATLISQNESRPHFLIELFHELQLLNTDYLRQRALYALQDIVSRHISESHEK
GENVKSVNSGTWIASNSELTPSESLATTDDETFEKNFERETHKISEQNDADNASVLSVSSNFEPFATDDLGNTVIHLDQALARMREYERM
KTEAESNSNMRCTCRIIEDGDGAGAETPVIENRSSQQPVSEVSTIPCPRIDTQQLDRQIKAIMKEVIPFLKEDPKWEFPRKNLVLGKTLG
EGEFGKVVKATAFHLKGRAGYTTVAVKMLKENASPSELRDLLSEFNVLKQVNHPHVIKLYGACSQDGPLLLIVEYAKYGSLRGFLRESRK
VGPGYLGSGGSRNSSSLDHPDERALTMGDLISFAWQISQGMQYLAEMKLVHRDLAARNILVAEGRKMKISDFGLSRDVYEEDSYVKRSQG
RIPVKWMAIESLFDHIYTTQSDVWSFGVLLWEIVTLGGNPYPGIPPERLFNLLKTGHRMERPDNCSEEMYRLMLQCWKQEPDKRPVFADI

--------------------------------------------------------------
>63341_63341_14_PCM1-RET_PCM1_chr8_17851129_ENST00000519253_RET_chr10_43612030_ENST00000355710_length(transcript)=8345nt_BP=5054nt
GCTGCGTAGCTGAGGTCGAAAAGGCGGCCACTGGGGCCGAGGCAGCCAGGAAACGTGTGGGCCTCTCTGCTGCGGTCTCCGAGGGCCGAC
CGCTGCCGGCGGCGGGTCGTGGGGGCTGACTGTCGCTCTGCCTTTGACAGGAGAGGCTGCTTCTTGTAGAGGAAACAGCTTTGAAGTGTG
GAGCGGGAAAGGAGCAGTTTCTGAGCTGCAAAAACTAGTTTCTAAACAGAGAGTTAATTGTTAAATCCAGTATGGCCACAGGAGGAGGTC
CCTTTGAAGATGGCATGAATGATCAGGATTTACCAAACTGGAGTAATGAGAATGTTGATGACAGGCTCAACAATATGGATTGGGGTGCCC
AACAGAAGAAAGCAAATAGATCATCAGAAAAGAATAAGAAAAAGTTTGGTGTAGAAAGTGATAAAAGAGTAACCAATGATATTTCTCCGG
AGTCGTCACCAGGAGTTGGAAGGCGAAGAACAAAGACTCCACATACGTTCCCACACAGTAGATACATGAGTCAGATGTCTGTCCCAGAGC
AGGCAGAATTAGAGAAACTGAAACAGCGGATAAACTTCAGTGATTTAGATCAGAGAAGCATTGGAAGTGATTCCCAAGGTAGAGCAACAG
CTGCTAACAACAAACGTCAGCTTAGTGAAAACCGAAAGCCCTTCAACTTTTTGCCTATGCAGATTAATACTAACAAGAGCAAAGATGCAT
CTACAAACCCCCCAAACAGAGAAACGATTGGATCAGCACAGTGTAAAGAGTTGTTTGCTTCTGCTTTAAGTAATGACCTCTTGCAAAACT
GTCAGGTGTCTGAAGAAGATGGGAGGGGAGAACCTGCAATGGAGAGCAGCCAGATTGTAAGCAGGCTTGTTCAAATTCGCGATTATATTA
CTAAAGCTAGTTCCATGCGGGAAGATCTTGTAGAGAAAAATGAGAGATCTGCTAATGTTGAGCGCCTTACTCATCTAATAGATCACCTTA
AAGAACAAGAGAAGTCATATATGAAATTTCTTAAAAAAATCCTTGCCAGAGATCCTCAGCAGGAGCCTATGGAAGAGATAGAAAATTTGA
AGAAACAACATGATTTATTAAAAAGAATGTTACAACAGCAGGAGCAACTAAGAGCTCTACAGGGACGGCAGGCTGCACTTCTAGCTCTGC
AACATAAAGCAGAGCAAGCTATTGCAGTGATGGATGATTCTGTTGTTGCAGAAACTGCAGGTAGCTTATCTGGCGTCAGTATCACATCTG
AACTAAATGAAGAATTGAATGACTTAATTCAGCGTTTTCATAATCAGCTTCGTGATTCTCAGCCTCCAGCTGTTCCAGACAATAGAAGAC
AGGCAGAAAGTCTTTCATTAACTAGGGAGGTTTCCCAGAGCAGGAAACCATCAGCTTCAGAACGTTTACCTGATGAGAAAGTCGAACTTT
TTAGCAAAATGAGAGTGCTACAGGAAAAGAAACAAAAAATGGACAAATTGCTTGGAGAACTTCATACACTTCGAGATCAGCATCTTAACA
ATTCATCATCCTCTCCACAAAGGAGTGTCGATCAGAGAAGTACTTCAGCTCCCTCTGCTTCTGTAGGCTTGGCACCGGTTGTCAATGGAG
AATCCAATAGCCTCACATCATCTGTTCCTTATCCTACTGCTTCTCTAGTATCTCAGAATGAGAGTGAAAACGAAGGCCACCTCAATCCAT
CTGAAAAACTCCAGAAGTTAAATGAAGTTCGAAAGAGATTGAATGAGCTAAGAGAATTAGTTCATTATTATGAACAAACGTCAGACATGA
TGACAGATGCTGTGAATGAAAACAGGAAAGATGAAGAAACTGAAGAGTCAGAATATGATTCTGAGCATGAAAATTCCGAGCCTGTTACTA
ACATTCGAAATCCACAAGTAGCTTCCACTTGGAATGAAGTAAATAGTCATAGTAATGCACAGTGTGTTTCTAATAATAGAGATGGGCGAA
CAGTTAATTCTAATTGTGAAATTAACAACAGATCTGCTGCCAACATAAGGGCTCTAAACATGCCTCCTTCTTTAGATTGTCGATATAATA
GAGAAGGGGAACAGGAGATTCATGTTGCACAAGGTGAAGATGATGAGGAGGAGGAGGAAGAAGCAGAAGAGGAGGGAGTCAGTGGAGCTT
CATTATCTAGTCACAGGAGCAGTCTGGTTGATGAGCATCCAGAAGATGCTGAATTTGAACAGAAGATCAACCGACTTATGGCTGCAAAAC
AGAAACTTAGACAGTTACAAGATCTTGTTGCTATGGTACAGGATGATGATGCAGCTCAAGGAGTTATCTCTGCCAGTGCATCAAATTTGG
ATGATTTCTACCCAGCAGAAGAAGACACCAAGCAAAATTCAAATAACACTAGAGGAAATGCCAATAAAACACAGAAAGATACTGGAGTAA
ATGAAAAGGCAAGAGAGAAATTTTATGAGGCTAAACTACAGCAGCAACAGAGAGAGCTAAAACAATTGCAGGAAGAAAGAAAGAAACTGA
TTGACATTCAGGAGAAAATTCAAGCATTGCAAACGGCATGCCCTGACTTACAGCTGTCAGCTGCTAGTGTGGGTAACTGTCCCACCAAAA
AATATATGCCAGCTGTTACTTCAACCCCAACTGTTAATCAACACGAGACCAGTACAAGCAAATCTGTTTTTGAGCCTGAAGATTCTTCAA
TAGTAGATAATGAGTTGTGGTCAGAAATGAGAAGACATGAAATGTTGAGGGAGGAGCTGCGACAGAGAAGAAAGCAGCTTGAAGCTCTGA
TGGCTGAACATCAGAGGAGGCAAGGTCTAGCTGAAACTGCATCTCCAGTGGCTGTGTCATTGAGAAGTGATGGATCTGAGAACCTATGTA
CTCCTCAGCAAAGTAGAACAGAAAAAACGATGGCAACTTGGGGAGGGTCTACCCAGTGTGCACTAGATGAAGAAGGAGATGAAGACGGTT
ACCTTTCTGAAGGAATTGTTCGGACAGATGAAGAGGAGGAAGAAGAGCAAGATGCCAGTTCCAATGATAACTTTTCTGTGTGTCCTTCTA
ACAGTGTGAATCATAACTCCTACAATGGAAAGGAAACTAAAAATAGGTGGAAGAACAATTGCCCTTTTTCGGCAGATGAAAATTATCGTC
CTTTAGCCAAGACAAGGCAACAGAATATCAGCATGCAACGGCAAGAAAACCTTCGTTGGGTGTCAGAGCTCTCTTACGTAGAAGAGAAAG
AACAATGGCAAGAACAAATCAATCAGCTAAAGAAACAGCTTGATTTTAGTGTCAGTATTTGTCAGACTTTGATGCAAGACCAGCAGACTC
TATCTTGTCTGCTACAAACTCTTCTCACGGGTCCTTACAGTGTTATGCCCAGCAATGTTGCATCTCCTCAAGTACACTTCATAATGCACC
AGTTGAACCAGTGCTATACTCAGCTAACATGGCAACAGAATAATGTTCAGAGGTTGAAACAAATGCTAAATGAACTTATGCGCCAGCAAA
ATCAGCATCCAGAAAAACCTGGAGGCAAGGAAAGAGGCAGTAGTGCATCGCACCCTCCTTCTCCCAGTTTATTTTGTCCTTTCAGCTTTC
CAACACAGCCTGTAAATCTCTTCAATATACCTGGATTTACTAACTTTTCATCATTTGCACCAGGTATGAATTTCAGCCCTTTATTTCCTT
CTAATTTTGGAGATTTTTCTCAGAATATCTCTACACCCAGTGAACAGCAGCAACCCTTAGCCCAGAATTCTTCAGGAAAAACAGAATATA
TGGCTTTTCCAAAACCTTTTGAAAGCAGTTCCTCTATTGGAGCAGAGAAACCAAGGAATAAAAAACTGCCTGAAGAGGAGGTGGAAAGCA
GTAGGACACCATGGTTATATGAACAAGAAGGTGAAGTAGAGAAACCATTTATCAAGACTGGATTTTCAGTGTCTGTAGAAAAATCTACAA
GTAGTAACCGCAAAAATCAATTAGATACAAACGGAAGAAGACGCCAGTTTGATGAAGAATCACTGGAAAGCTTTAGCAGTATGCCTGATC
CAGTAGATCCAACAACAGTGACTAAAACATTCAAGACAAGAAAAGCGTCTGCACAGGCCAGCCTGGCATCTAAAGATAAAACTCCCAAGT
CAAAAAGTAAGAAGAGGAATTCTACTCAGCTGAAAAGCAGAGTTAAAAACATCAGGTATGAAAGTGCCAGTATGTCTAGCACATGTGAAC
CTTGCAAAAGTAGGAACAGACATTCAGCCCAGACTGAAGAGCCTGTTCAAGCAAAAGTATTCAGCAGAAAGAATCATGAGCAACTGGAAA
AAATAATAAAATGTAATAGGTCTACAGAAATATCTTCAGAAACTGGGAGTGATTTTTCCATGTTTGAAGCTTTGCGAGATACTATTTATT
CTGAAGTAGCTACATTAATTTCTCAAAATGAATCTCGTCCACATTTTCTTATTGAACTCTTCCATGAGCTGCAGCTACTAAACACAGACT
ACTTGAGACAGAGGGCTTTATATGCATTGCAGGACATAGTATCCAGACATATTTCTGAGAGCCATGAAAAAGGAGAAAATGTAAAGTCAG
TAAACTCTGGTACTTGGATAGCATCAAACTCAGAACTTACTCCTAGTGAGAGCCTTGCTACTACTGATGATGAAACTTTTGAGAAGAACT
TTGAAAGAGAAACCCATAAAATAAGTGAGCAAAATGATGCTGATAATGCTAGTGTCCTGTCTGTATCATCAAATTTTGAGCCTTTTGCAA
CAGATGATCTAGGTAACACCGTGATTCACTTAGATCAAGCATTAGCCAGAATGAGAGAATATGAGCGTATGAAGACTGAGGCTGAAAGTA
ACTCAAATATGAGATGCACCTGCAGGATTATTGAGGATGGAGATGGTGCTGGTGCAGAAACTCCCGTTATTGAAAATCGTAGTTCACAAC
AACCTGTAAGTGAAGTTTCTACCATCCCATGTCCTAGAATTGATACTCAGCAGCTGGACCGGCAAATTAAAGCAATTATGAAAGAAGTCA
TTCCTTTTTTGAAGGAGGATCCAAAGTGGGAATTCCCTCGGAAGAACTTGGTTCTTGGAAAAACTCTAGGAGAAGGCGAATTTGGAAAAG
TGGTCAAGGCAACGGCCTTCCATCTGAAAGGCAGAGCAGGGTACACCACGGTGGCCGTGAAGATGCTGAAAGAGAACGCCTCCCCGAGTG
AGCTGCGAGACCTGCTGTCAGAGTTCAACGTCCTGAAGCAGGTCAACCACCCACATGTCATCAAATTGTATGGGGCCTGCAGCCAGGATG
GCCCGCTCCTCCTCATCGTGGAGTACGCCAAATACGGCTCCCTGCGGGGCTTCCTCCGCGAGAGCCGCAAAGTGGGGCCTGGCTACCTGG
GCAGTGGAGGCAGCCGCAACTCCAGCTCCCTGGACCACCCGGATGAGCGGGCCCTCACCATGGGCGACCTCATCTCATTTGCCTGGCAGA
TCTCACAGGGGATGCAGTATCTGGCCGAGATGAAGCTCGTTCATCGGGACTTGGCAGCCAGAAACATCCTGGTAGCTGAGGGGCGGAAGA
TGAAGATTTCGGATTTCGGCTTGTCCCGAGATGTTTATGAAGAGGATTCCTACGTGAAGAGGAGCCAGGGTCGGATTCCAGTTAAATGGA
TGGCAATTGAATCCCTTTTTGATCATATCTACACCACGCAAAGTGATGTATGGTCTTTTGGTGTCCTGCTGTGGGAGATCGTGACCCTAG
GGGGAAACCCCTATCCTGGGATTCCTCCTGAGCGGCTCTTCAACCTTCTGAAGACCGGCCACCGGATGGAGAGGCCAGACAACTGCAGCG
AGGAGATGTACCGCCTGATGCTGCAATGCTGGAAGCAGGAGCCGGACAAAAGGCCGGTGTTTGCGGACATCAGCAAAGACCTGGAGAAGA
TGATGGTTAAGAGGAGAGACTACTTGGACCTTGCGGCGTCCACTCCATCTGACTCCCTGATTTATGACGACGGCCTCTCAGAGGAGGAGA
CACCGCTGGTGGACTGTAATAATGCCCCCCTCCCTCGAGCCCTCCCTTCCACATGGATTGAAAACAAACTCTATGGCATGTCAGACCCGA
ACTGGCCTGGAGAGAGTCCTGTACCACTCACGAGAGCTGATGGCACTAACACTGGGTTTCCAAGATATCCAAATGATAGTGTATATGCTA
ACTGGATGCTTTCACCCTCAGCGGCAAAATTAATGGACACGTTTGATAGTTAACATTTCTTTGTGAAAGGTAATGGACTCACAAGGGGAA
GAAACATGCTGAGAATGGAAAGTCTACCGGCCCTTTCTTTGTGAACGTCACATTGGCCGAGCCGTGTTCAGTTCCCAGGTGGCAGACTCG
TTTTTGGTAGTTTGTTTTAACTTCCAAGGTGGTTTTACTTCTGATAGCCGGTGATTTTCCCTCCTAGCAGACATGCCACACCGGGTAAGA
GCTCTGAGTCTTAGTGGTTAAGCATTCCTTTCTCTTCAGTGCCCAGCAGCACCCAGTGTTGGTCTGTGTCCATCAGTGACCACCAACATT
CTGTGTTCACATGTGTGGGTCCAACACTTACTACCTGGTGTATGAAATTGGACCTGAACTGTTGGATTTTTCTAGTTGCCGCCAAACAAG
GCAAAAAAATTTAAACATGAAGCACACACACAAAAAAGGCAGTAGGAAAAATGCTGGCCCTGATGACCTGTCCTTATTCAGAATGAGAGA
CTGCGGGGGGGGCCTGGGGGTAGTGTCAATGCCCCTCCAGGGCTGGAGGGGAAGAGGGGCCCCGAGGATGGGCCTGGGCTCAGCATTCGA
GATCTTGAGAATGATTTTTTTTAAATCATGCAACCTTTCCTTAGGAAGACATTTGGTTTTCATCATGATTAAGATGATTCCTAGATTTAG
CACAATGGAGAGATTCCATGCCATCTTTACTATGTGGATGGTGGTATCAGGGAAGAGGGCTCACAAGACACATTTGTCCCCCGGGCCCAC
CACATCATCCTCACGTGTTCGGTACTGAGCAGCCACTACCCCTGATGAGAACAGTATGAAGAAAGGGGGCTGTTGGAGTCCCAGAATTGC
TGACAGCAGAGGCTTTGCTGCTGTGAATCCCACCTGCCACCAGCCTGCAGCACACCCCACAGCCAAGTAGAGGCGAAAGCAGTGGCTCAT
CCTACCTGTTAGGAGCAGGTAGGGCTTGTACTCACTTTAATTTGAATCTTATCAACTTACTCATAAAGGGACAGGCTAGCTAGCTGTGTT
AGAAGTAGCAATGACAATGACCAAGGACTGCTACACCTCTGATTACAATTCTGATGTGAAAAAGATGGTGTTTGGCTCTTATAGAGCCTG
TGTGAAAGGCCCATGGATCAGCTCTTCCTGTGTTTGTAATTTAATGCTGCTACAAGATGTTTCTGTTTCTTAGATTCTGACCATGACTCA
TAAGCTTCTTGTCATTCTTCATTGCTTGTTTGTGGTCACAGATGCACAACACTCCTCCAGTCTTGTGGGGGCAGCTTTTGGGAAGTCTCA
GCAGCTCTTCTGGCTGTGTTGTCAGCACTGTAACTTCGCAGAAAAGAGTCGGATTACCAAAACACTGCCTGCTCTTCAGACTTAAAGCAC
TGATAGGACTTAAAATAGTCTCATTCAAATACTGTATTTTATATAGGCATTTCACAAAAACAGCAAAATTGTGGCATTTTGTGAGGCCAA
GGCTTGGATGCGTGTGTAATAGAGCCTTGTGGTGTGTGCGCACACACCCAGAGGGAGAGTTTGAAAAATGCTTATTGGACACGTAACCTG
GCTCTAATTTGGGCTGTTTTTCAGATACACTGTGATAAGTTCTTTTACAAATATCTATAGACATGGTAAACTTTTGGTTTTCAGATATGC
TTAATGATAGTCTTACTAAATGCAGAAATAAGAATAAACTTTCTCAAATTATTAAAAATGCCTACACAGTAAGTGTGAATTGCTGCAACA
GGTTTGTTCTCAGGAGGGTAAGAACTCCAGGTCTAAACAGCTGACCCAGTGATGGGGAATTTATCCTTGACCAATTTATCCTTGACCAAT
AACCTAATTGTCTATTCCTGAGTTATAAAAGTCCCCATCCTTATTAGCTCTACTGGAATTTTCATACACGTAAATGCAGAAGTTACTAAG
TATTAAGTATTACTGAGTATTAAGTAGTAATCTGTCAGTTATTAAAATTTGTAAAATCTATTTATGAAAGGTCATTAAACCAGATCATGT

>63341_63341_14_PCM1-RET_PCM1_chr8_17851129_ENST00000519253_RET_chr10_43612030_ENST00000355710_length(amino acids)=2003AA_BP=1601
MATGGGPFEDGMNDQDLPNWSNENVDDRLNNMDWGAQQKKANRSSEKNKKKFGVESDKRVTNDISPESSPGVGRRRTKTPHTFPHSRYMS
QMSVPEQAELEKLKQRINFSDLDQRSIGSDSQGRATAANNKRQLSENRKPFNFLPMQINTNKSKDASTNPPNRETIGSAQCKELFASALS
NDLLQNCQVSEEDGRGEPAMESSQIVSRLVQIRDYITKASSMREDLVEKNERSANVERLTHLIDHLKEQEKSYMKFLKKILARDPQQEPM
EEIENLKKQHDLLKRMLQQQEQLRALQGRQAALLALQHKAEQAIAVMDDSVVAETAGSLSGVSITSELNEELNDLIQRFHNQLRDSQPPA
VPDNRRQAESLSLTREVSQSRKPSASERLPDEKVELFSKMRVLQEKKQKMDKLLGELHTLRDQHLNNSSSSPQRSVDQRSTSAPSASVGL
APVVNGESNSLTSSVPYPTASLVSQNESENEGHLNPSEKLQKLNEVRKRLNELRELVHYYEQTSDMMTDAVNENRKDEETEESEYDSEHE
NSEPVTNIRNPQVASTWNEVNSHSNAQCVSNNRDGRTVNSNCEINNRSAANIRALNMPPSLDCRYNREGEQEIHVAQGEDDEEEEEEAEE
EGVSGASLSSHRSSLVDEHPEDAEFEQKINRLMAAKQKLRQLQDLVAMVQDDDAAQGVISASASNLDDFYPAEEDTKQNSNNTRGNANKT
QKDTGVNEKAREKFYEAKLQQQQRELKQLQEERKKLIDIQEKIQALQTACPDLQLSAASVGNCPTKKYMPAVTSTPTVNQHETSTSKSVF
EPEDSSIVDNELWSEMRRHEMLREELRQRRKQLEALMAEHQRRQGLAETASPVAVSLRSDGSENLCTPQQSRTEKTMATWGGSTQCALDE
EGDEDGYLSEGIVRTDEEEEEEQDASSNDNFSVCPSNSVNHNSYNGKETKNRWKNNCPFSADENYRPLAKTRQQNISMQRQENLRWVSEL
SYVEEKEQWQEQINQLKKQLDFSVSICQTLMQDQQTLSCLLQTLLTGPYSVMPSNVASPQVHFIMHQLNQCYTQLTWQQNNVQRLKQMLN
ELMRQQNQHPEKPGGKERGSSASHPPSPSLFCPFSFPTQPVNLFNIPGFTNFSSFAPGMNFSPLFPSNFGDFSQNISTPSEQQQPLAQNS
SGKTEYMAFPKPFESSSSIGAEKPRNKKLPEEEVESSRTPWLYEQEGEVEKPFIKTGFSVSVEKSTSSNRKNQLDTNGRRRQFDEESLES
FSSMPDPVDPTTVTKTFKTRKASAQASLASKDKTPKSKSKKRNSTQLKSRVKNIRYESASMSSTCEPCKSRNRHSAQTEEPVQAKVFSRK
NHEQLEKIIKCNRSTEISSETGSDFSMFEALRDTIYSEVATLISQNESRPHFLIELFHELQLLNTDYLRQRALYALQDIVSRHISESHEK
GENVKSVNSGTWIASNSELTPSESLATTDDETFEKNFERETHKISEQNDADNASVLSVSSNFEPFATDDLGNTVIHLDQALARMREYERM
KTEAESNSNMRCTCRIIEDGDGAGAETPVIENRSSQQPVSEVSTIPCPRIDTQQLDRQIKAIMKEVIPFLKEDPKWEFPRKNLVLGKTLG
EGEFGKVVKATAFHLKGRAGYTTVAVKMLKENASPSELRDLLSEFNVLKQVNHPHVIKLYGACSQDGPLLLIVEYAKYGSLRGFLRESRK
VGPGYLGSGGSRNSSSLDHPDERALTMGDLISFAWQISQGMQYLAEMKLVHRDLAARNILVAEGRKMKISDFGLSRDVYEEDSYVKRSQG
RIPVKWMAIESLFDHIYTTQSDVWSFGVLLWEIVTLGGNPYPGIPPERLFNLLKTGHRMERPDNCSEEMYRLMLQCWKQEPDKRPVFADI
SKDLEKMMVKRRDYLDLAASTPSDSLIYDDGLSEEETPLVDCNNAPLPRALPSTWIENKLYGMSDPNWPGESPVPLTRADGTNTGFPRYP

--------------------------------------------------------------
>63341_63341_15_PCM1-RET_PCM1_chr8_17851129_ENST00000524226_RET_chr10_43612030_ENST00000340058_length(transcript)=6557nt_BP=4724nt
AGCAGTTTCTGAGCTGCAAAAACTAGTTTCTAAACAGAGAGTTAATTGTTAAATCCAGTATGGCCACAGGAGGAGGTCCCTTTGAAGATG
GCATGAATGATCAGGATTTACCAAACTGGAGTAATGAGAATGTTGATGACAGGCTCAACAATATGGATTGGGGTGCCCAACAGAAGAAAG
CAAATAGATCATCAGAAAAGAATAAGAAAAAGTTTGGTGTAGAAAGTGATAAAAGAGTAACCAATGATATTTCTCCGGAGTCGTCACCAG
GAGTTGGAAGGCGAAGAACAAAGACTCCACATACGTTCCCACACAGTAGATACATGAGTCAGATGTCTGTCCCAGAGCAGGCAGAATTAG
AGAAACTGAAACAGCGGATAAACTTCAGTGATTTAGATCAGAGAAGCATTGGAAGTGATTCCCAAGGTAGAGCAACAGCTGCTAACAACA
AACGTCAGCTTAGTGAAAACCGAAAGCCCTTCAACTTTTTGCCTATGCAGATTAATACTAACAAGAGCAAAGATGCATCTACAAACCCCC
CAAACAGAGAAACGATTGGATCAGCACAGTGTAAAGAGTTGTTTGCTTCTGCTTTAAGTAATGACCTCTTGCAAAACTGTCAGGTGTCTG
AAGAAGATGGGAGGGGAGAACCTGCAATGGAGAGCAGCCAGATTGTAAGCAGGCTTGTTCAAATTCGCGATTATATTACTAAAGCTAGTT
CCATGCGGGAAGATCTTGTAGAGAAAAATGAGAGATCTGCTAATGTTGAGCGCCTTACTCATCTAATAGATCACCTTAAAGAACAAGAGA
AGTCATATATGAAATTTCTTAAAAAAATCCTTGCCAGAGATCCTCAGCAGGAGCCTATGGAAGAGATAGAAAATTTGAAGAAACAACATG
ATTTATTAAAAAGAATGTTACAACAGCAGGAGCAACTAAGAGCTCTACAGGGACGGCAGGCTGCACTTCTAGCTCTGCAACATAAAGCAG
AGCAAGCTATTGCAGTGATGGATGATTCTGTTGTTGCAGAAACTGCAGGTAGCTTATCTGGCGTCAGTATCACATCTGAACTAAATGAAG
AATTGAATGACTTAATTCAGCGTTTTCATAATCAGCTTCGTGATTCTCAGCCTCCAGCTGTTCCAGACAATAGAAGACAGGCAGAAAGTC
TTTCATTAACTAGGGAGGTTTCCCAGAGCAGGAAACCATCAGCTTCAGAACGTTTACCTGATGAGAAAGTCGAACTTTTTAGCAAAATGA
GAGTGCTACAGGAAAAGAAACAAAAAATGGACAAATTGCTTGGAGAACTTCATACACTTCGAGATCAGCATCTTAACAATTCATCATCCT
CTCCACAAAGGAGTGTCGATCAGAGAAGTACTTCAGCTCCCTCTGCTTCTGTAGGCTTGGCACCGGTTGTCAATGGAGAATCCAATAGCC
TCACATCATCTGTTCCTTATCCTACTGCTTCTCTAGTATCTCAGAATGAGAGTGAAAACGAAGGCCACCTCAATCCATCTGAAAAACTCC
AGAAGTTAAATGAAGTTCGAAAGAGATTGAATGAGCTAAGAGAATTAGTTCATTATTATGAACAAACGTCAGACATGATGACAGATGCTG
TGAATGAAAACAGGAAAGATGAAGAAACTGAAGAGTCAGAATATGATTCTGAGCATGAAAATTCCGAGCCTGTTACTAACATTCGAAATC
CACAAGTAGCTTCCACTTGGAATGAAGTAAATAGTCATAGTAATGCACAGTGTGTTTCTAATAATAGAGATGGGCGAACAGTTAATTCTA
ATTGTGAAATTAACAACAGATCTGCTGCCAACATAAGGGCTCTAAACATGCCTCCTTCTTTAGCAGATTGTCGATATAATAGAGAAGGGG
AACAGGAGATTCATGTTGCACAAGGTGAAGATGATGAGGAGGAGGAGGAAGAAGCAGAAGAGGAGGGAGTCAGTGGAGCTTCATTATCTA
GTCACAGGAGCAGTCTGGTTGATGAGCATCCAGAAGATGCTGAATTTGAACAGAAGATCAACCGACTTATGGCTGCAAAACAGAAACTTA
GACAGTTACAAGATCTTGTTGCTATGGTACAGGATGATGATGCAGCTCAAGGAGTTATCTCTGCCAGTGCATCAAATTTGGATGATTTCT
ACCCAGCAGAAGAAGACACCAAGCAAAATTCAAATAACACTAGAGGAAATGCCAATAAAACACAGAAAGATACTGGAGTAAATGAAAAGG
CAAGAGAGAAATTTTATGAGGCTAAACTACAGCAGCAACAGAGAGAGCTAAAACAATTGCAGGAAGAAAGAAAGAAACTGATTGACATTC
AGGAGAAAATTCAAGCATTGCAAACGGCATGCCCTGACTTACAGCTGTCAGCTGCTAGTGTGGGTAACTGTCCCACCAAAAAATATATGC
CAGCTGTTACTTCAACCCCAACTGTTAATCAACACGAGACCAGTACAAGCAAATCTGTTTTTGAGCCTGAAGATTCTTCAATAGTAGATA
ATGAGTTGTGGTCAGAAATGAGAAGACATGAAATGTTGAGGGAGGAGCTGCGACAGAGAAGAAAGCAGCTTGAAGCTCTGATGGCTGAAC
ATCAGAGGAGGCAAGGTCTAGCTGAAACTGCATCTCCAGTGGCTGTGTCATTGAGAAGTGATGGATCTGAGAACCTATGTACTCCTCAGC
AAAGTAGAACAGAAAAAACGATGGCAACTTGGGGAGGGTCTACCCAGTGTGCACTAGATGAAGAAGGAGATGAAGACGGTTACCTTTCTG
AAGGAATTGTTCGGACAGATGAAGAGGAGGAAGAAGAGCAAGATGCCAGTTCCAATGATAACTTTTCTGTGTGTCCTTCTAACAGTGTGA
ATCATAACTCCTACAATGGAAAGGAAACTAAAAATAGGTGGAAGAACAATTGCCCTTTTTCGGCAGATGAAAATTATCGTCCTTTAGCCA
AGACAAGGCAACAGAATATCAGCATGCAACGGCAAGAAAACCTTCGTTGGGTGTCAGAGCTCTCTTACGTAGAAGAGAAAGAACAATGGC
AAGAACAAATCAATCAGCTAAAGAAACAGCTTGATTTTAGTGTCAGTATTTGTCAGACTTTGATGCAAGACCAGCAGACTCTATCTTGTC
TGCTACAAACTCTTCTCACGGGTCCTTACAGTGTTATGCCCAGCAATGTTGCATCTCCTCAAGTACACTTCATAATGCACCAGTTGAACC
AGTGCTATACTCAGCTAACATGGCAACAGAATAATGTTCAGAGGTTGAAACAAATGCTAAATGAACTTATGCGCCAGCAAAATCAGCATC
CAGAAAAACCTGGAGGCAAGGAAAGAGGCAGTAGTGCATCGCACCCTCCTTCTCCCAGTTTATTTTGTCCTTTCAGCTTTCCAACACAGC
CTGTAAATCTCTTCAATATACCTGGATTTACTAACTTTTCATCATTTGCACCAGGTATGAATTTCAGCCCTTTATTTCCTTCTAATTTTG
GAGATTTTTCTCAGAATATCTCTACACCCAGTGAACAGCAGCAACCCTTAGCCCAGAATTCTTCAGGAAAAACAGAATATATGGCTTTTC
CAAAACCTTTTGAAAGCAGTTCCTCTATTGGAGCAGAGAAACCAAGGAATAAAAAACTGCCTGAAGAGGAGGTGGAAAGCAGTAGGACAC
CATGGTTATATGAACAAGAAGGTGAAGTAGAGAAACCATTTATCAAGACTGGATTTTCAGTGTCTGTAGAAAAATCTACAAGTAGTAACC
GCAAAAATCAATTAGATACAAACGGAAGAAGACGCCAGTTTGATGAAGAATCACTGGAAAGCTTTAGCAGTATGCCTGATCCAGTAGATC
CAACAACAGTGACTAAAACATTCAAGACAAGAAAAGCGTCTGCACAGGCCAGCCTGGCATCTAAAGATAAAACTCCCAAGTCAAAAAGTA
AGAAGAGGAATTCTACTCAGCTGAAAAGCAGAGTTAAAAACATCAAAACTGGGAGTGATTTTTCCATGTTTGAAGCTTTGCGAGATACTA
TTTATTCTGAAGTAGCTACATTAATTTCTCAAAATGAATCTCGTCCACATTTTCTTATTGAACTCTTCCATGAGCTGCAGCTACTAAACA
CAGACTACTTGAGACAGAGGGCTTTATATGCATTGCAGGACATAGTATCCAGACATATTTCTGAGAGCCATGAAAAAGGAGAAAATGTAA
AGTCAGTAAACTCTGGTACTTGGATAGCATCAAACTCAGAACTTACTCCTAGTGAGAGCCTTGCTACTACTGATGATGAAACTTTTGAGA
AGAACTTTGAAAGAGAAACCCATAAAATAAGTGAGCAAAATGATGCTGATAATGCTAGTGTCCTGTCTGTATCATCAAATTTTGAGCCTT
TTGCAACAGATGATCTAGGTAACACCGTGATTCACTTAGATCAAGCATTAGCCAGAATGAGAGAATATGAGCGTATGAAGACTGAGGCTG
AAAGTAACTCAAATATGAGATGCACCTGCAGGATTATTGAGGATGGAGATGGTGCTGGTGCAGGTACTACAGTTAATAATTTAGAAGAAA
CTCCCGTTATTGAAAATCGTAGTTCACAACAACCTGTAAGTGAAGTTTCTACCATCCCATGTCCTAGAATTGATACTCAGCAGCTGGACC
GGCAAATTAAAGCAATTATGAAAGAAGTCATTCCTTTTTTGAAGGAGGATCCAAAGTGGGAATTCCCTCGGAAGAACTTGGTTCTTGGAA
AAACTCTAGGAGAAGGCGAATTTGGAAAAGTGGTCAAGGCAACGGCCTTCCATCTGAAAGGCAGAGCAGGGTACACCACGGTGGCCGTGA
AGATGCTGAAAGAGAACGCCTCCCCGAGTGAGCTGCGAGACCTGCTGTCAGAGTTCAACGTCCTGAAGCAGGTCAACCACCCACATGTCA
TCAAATTGTATGGGGCCTGCAGCCAGGATGGCCCGCTCCTCCTCATCGTGGAGTACGCCAAATACGGCTCCCTGCGGGGCTTCCTCCGCG
AGAGCCGCAAAGTGGGGCCTGGCTACCTGGGCAGTGGAGGCAGCCGCAACTCCAGCTCCCTGGACCACCCGGATGAGCGGGCCCTCACCA
TGGGCGACCTCATCTCATTTGCCTGGCAGATCTCACAGGGGATGCAGTATCTGGCCGAGATGAAGCTCGTTCATCGGGACTTGGCAGCCA
GAAACATCCTGGTAGCTGAGGGGCGGAAGATGAAGATTTCGGATTTCGGCTTGTCCCGAGATGTTTATGAAGAGGATTCCTACGTGAAGA
GGAGCCAGGGTCGGATTCCAGTTAAATGGATGGCAATTGAATCCCTTTTTGATCATATCTACACCACGCAAAGTGATGTATGGTCTTTTG
GTGTCCTGCTGTGGGAGATCGTGACCCTAGGGGGAAACCCCTATCCTGGGATTCCTCCTGAGCGGCTCTTCAACCTTCTGAAGACCGGCC
ACCGGATGGAGAGGCCAGACAACTGCAGCGAGGAGATGTACCGCCTGATGCTGCAATGCTGGAAGCAGGAGCCGGACAAAAGGCCGGTGT
TTGCGGACATCAGCAAAGACCTGGAGAAGATGATGGTTAAGAGGAGAGACTACTTGGACCTTGCGGCGTCCACTCCATCTGACTCCCTGA
TTTATGACGACGGCCTCTCAGAGGAGGAGACACCGCTGGTGGACTGTAATAATGCCCCCCTCCCTCGAGCCCTCCCTTCCACATGGATTG
AAAACAAACTCTATGGTAGAATTTCCCATGCATTTACTAGATTCTAGCACCGCTGTCCCCTTTGCACTATCCTTCCTCTCTGTGATGCTT
TTTAAAAATGTTTCTGGTCTGAACAAAACCAAAGTCTGCTCTGAACCTTTTTATTTGTAAATGTCTGACTTTGCATCCAGTTTACATTTA
GGCATTATTGCAACTATGTTTTTCTAAAAGGATGTGAAAATAAGTGTAATTACCACATTGCCCAGCAACTTAGGATGGTAGAGGAAAAAA
CAGATCAGGGCGGAACTCTCAGGGGAGACCAAGAACAGGTTGAATAAGGCGCTTCTGGGGTGGGAATCAAGTCATAGTACTTCTACTTTA
ACTAAGTGGATAAATATACAAATCTGGGGAGGTATTCAGTTGAGAAAGGAGCCACCAGCACCACTCAGCCTGCACTGGGAGCACAGCCAG
GTTCCCCCAGACCCCTCCTGGGCAGGCAGGTGCCTCTCAGAGGCCACCCGGCACTGGCGAGCAGCCACTGGCCAAGCCTCAGCCCCAGTC
CCAGCCACATGTCCTCCATCAGGGGTAGCGAGGTTGCAGGAGCTGGCTGGCCCTGGGAGGACGCACCCCCACTGCTGTTTTCACATCCTT
TCCCTTACCCACCTTCAGGACGGTTGTCACTTATGAAGTCAGTGCTAAAGCTGGAGCAGTTGCTTTTTGAAAGAACATGGTCTGTGGTGC

>63341_63341_15_PCM1-RET_PCM1_chr8_17851129_ENST00000524226_RET_chr10_43612030_ENST00000340058_length(amino acids)=1915AA_BP=1555
MATGGGPFEDGMNDQDLPNWSNENVDDRLNNMDWGAQQKKANRSSEKNKKKFGVESDKRVTNDISPESSPGVGRRRTKTPHTFPHSRYMS
QMSVPEQAELEKLKQRINFSDLDQRSIGSDSQGRATAANNKRQLSENRKPFNFLPMQINTNKSKDASTNPPNRETIGSAQCKELFASALS
NDLLQNCQVSEEDGRGEPAMESSQIVSRLVQIRDYITKASSMREDLVEKNERSANVERLTHLIDHLKEQEKSYMKFLKKILARDPQQEPM
EEIENLKKQHDLLKRMLQQQEQLRALQGRQAALLALQHKAEQAIAVMDDSVVAETAGSLSGVSITSELNEELNDLIQRFHNQLRDSQPPA
VPDNRRQAESLSLTREVSQSRKPSASERLPDEKVELFSKMRVLQEKKQKMDKLLGELHTLRDQHLNNSSSSPQRSVDQRSTSAPSASVGL
APVVNGESNSLTSSVPYPTASLVSQNESENEGHLNPSEKLQKLNEVRKRLNELRELVHYYEQTSDMMTDAVNENRKDEETEESEYDSEHE
NSEPVTNIRNPQVASTWNEVNSHSNAQCVSNNRDGRTVNSNCEINNRSAANIRALNMPPSLADCRYNREGEQEIHVAQGEDDEEEEEEAE
EEGVSGASLSSHRSSLVDEHPEDAEFEQKINRLMAAKQKLRQLQDLVAMVQDDDAAQGVISASASNLDDFYPAEEDTKQNSNNTRGNANK
TQKDTGVNEKAREKFYEAKLQQQQRELKQLQEERKKLIDIQEKIQALQTACPDLQLSAASVGNCPTKKYMPAVTSTPTVNQHETSTSKSV
FEPEDSSIVDNELWSEMRRHEMLREELRQRRKQLEALMAEHQRRQGLAETASPVAVSLRSDGSENLCTPQQSRTEKTMATWGGSTQCALD
EEGDEDGYLSEGIVRTDEEEEEEQDASSNDNFSVCPSNSVNHNSYNGKETKNRWKNNCPFSADENYRPLAKTRQQNISMQRQENLRWVSE
LSYVEEKEQWQEQINQLKKQLDFSVSICQTLMQDQQTLSCLLQTLLTGPYSVMPSNVASPQVHFIMHQLNQCYTQLTWQQNNVQRLKQML
NELMRQQNQHPEKPGGKERGSSASHPPSPSLFCPFSFPTQPVNLFNIPGFTNFSSFAPGMNFSPLFPSNFGDFSQNISTPSEQQQPLAQN
SSGKTEYMAFPKPFESSSSIGAEKPRNKKLPEEEVESSRTPWLYEQEGEVEKPFIKTGFSVSVEKSTSSNRKNQLDTNGRRRQFDEESLE
SFSSMPDPVDPTTVTKTFKTRKASAQASLASKDKTPKSKSKKRNSTQLKSRVKNIKTGSDFSMFEALRDTIYSEVATLISQNESRPHFLI
ELFHELQLLNTDYLRQRALYALQDIVSRHISESHEKGENVKSVNSGTWIASNSELTPSESLATTDDETFEKNFERETHKISEQNDADNAS
VLSVSSNFEPFATDDLGNTVIHLDQALARMREYERMKTEAESNSNMRCTCRIIEDGDGAGAGTTVNNLEETPVIENRSSQQPVSEVSTIP
CPRIDTQQLDRQIKAIMKEVIPFLKEDPKWEFPRKNLVLGKTLGEGEFGKVVKATAFHLKGRAGYTTVAVKMLKENASPSELRDLLSEFN
VLKQVNHPHVIKLYGACSQDGPLLLIVEYAKYGSLRGFLRESRKVGPGYLGSGGSRNSSSLDHPDERALTMGDLISFAWQISQGMQYLAE
MKLVHRDLAARNILVAEGRKMKISDFGLSRDVYEEDSYVKRSQGRIPVKWMAIESLFDHIYTTQSDVWSFGVLLWEIVTLGGNPYPGIPP
ERLFNLLKTGHRMERPDNCSEEMYRLMLQCWKQEPDKRPVFADISKDLEKMMVKRRDYLDLAASTPSDSLIYDDGLSEEETPLVDCNNAP

--------------------------------------------------------------
>63341_63341_16_PCM1-RET_PCM1_chr8_17851129_ENST00000524226_RET_chr10_43612030_ENST00000355710_length(transcript)=8015nt_BP=4724nt
AGCAGTTTCTGAGCTGCAAAAACTAGTTTCTAAACAGAGAGTTAATTGTTAAATCCAGTATGGCCACAGGAGGAGGTCCCTTTGAAGATG
GCATGAATGATCAGGATTTACCAAACTGGAGTAATGAGAATGTTGATGACAGGCTCAACAATATGGATTGGGGTGCCCAACAGAAGAAAG
CAAATAGATCATCAGAAAAGAATAAGAAAAAGTTTGGTGTAGAAAGTGATAAAAGAGTAACCAATGATATTTCTCCGGAGTCGTCACCAG
GAGTTGGAAGGCGAAGAACAAAGACTCCACATACGTTCCCACACAGTAGATACATGAGTCAGATGTCTGTCCCAGAGCAGGCAGAATTAG
AGAAACTGAAACAGCGGATAAACTTCAGTGATTTAGATCAGAGAAGCATTGGAAGTGATTCCCAAGGTAGAGCAACAGCTGCTAACAACA
AACGTCAGCTTAGTGAAAACCGAAAGCCCTTCAACTTTTTGCCTATGCAGATTAATACTAACAAGAGCAAAGATGCATCTACAAACCCCC
CAAACAGAGAAACGATTGGATCAGCACAGTGTAAAGAGTTGTTTGCTTCTGCTTTAAGTAATGACCTCTTGCAAAACTGTCAGGTGTCTG
AAGAAGATGGGAGGGGAGAACCTGCAATGGAGAGCAGCCAGATTGTAAGCAGGCTTGTTCAAATTCGCGATTATATTACTAAAGCTAGTT
CCATGCGGGAAGATCTTGTAGAGAAAAATGAGAGATCTGCTAATGTTGAGCGCCTTACTCATCTAATAGATCACCTTAAAGAACAAGAGA
AGTCATATATGAAATTTCTTAAAAAAATCCTTGCCAGAGATCCTCAGCAGGAGCCTATGGAAGAGATAGAAAATTTGAAGAAACAACATG
ATTTATTAAAAAGAATGTTACAACAGCAGGAGCAACTAAGAGCTCTACAGGGACGGCAGGCTGCACTTCTAGCTCTGCAACATAAAGCAG
AGCAAGCTATTGCAGTGATGGATGATTCTGTTGTTGCAGAAACTGCAGGTAGCTTATCTGGCGTCAGTATCACATCTGAACTAAATGAAG
AATTGAATGACTTAATTCAGCGTTTTCATAATCAGCTTCGTGATTCTCAGCCTCCAGCTGTTCCAGACAATAGAAGACAGGCAGAAAGTC
TTTCATTAACTAGGGAGGTTTCCCAGAGCAGGAAACCATCAGCTTCAGAACGTTTACCTGATGAGAAAGTCGAACTTTTTAGCAAAATGA
GAGTGCTACAGGAAAAGAAACAAAAAATGGACAAATTGCTTGGAGAACTTCATACACTTCGAGATCAGCATCTTAACAATTCATCATCCT
CTCCACAAAGGAGTGTCGATCAGAGAAGTACTTCAGCTCCCTCTGCTTCTGTAGGCTTGGCACCGGTTGTCAATGGAGAATCCAATAGCC
TCACATCATCTGTTCCTTATCCTACTGCTTCTCTAGTATCTCAGAATGAGAGTGAAAACGAAGGCCACCTCAATCCATCTGAAAAACTCC
AGAAGTTAAATGAAGTTCGAAAGAGATTGAATGAGCTAAGAGAATTAGTTCATTATTATGAACAAACGTCAGACATGATGACAGATGCTG
TGAATGAAAACAGGAAAGATGAAGAAACTGAAGAGTCAGAATATGATTCTGAGCATGAAAATTCCGAGCCTGTTACTAACATTCGAAATC
CACAAGTAGCTTCCACTTGGAATGAAGTAAATAGTCATAGTAATGCACAGTGTGTTTCTAATAATAGAGATGGGCGAACAGTTAATTCTA
ATTGTGAAATTAACAACAGATCTGCTGCCAACATAAGGGCTCTAAACATGCCTCCTTCTTTAGCAGATTGTCGATATAATAGAGAAGGGG
AACAGGAGATTCATGTTGCACAAGGTGAAGATGATGAGGAGGAGGAGGAAGAAGCAGAAGAGGAGGGAGTCAGTGGAGCTTCATTATCTA
GTCACAGGAGCAGTCTGGTTGATGAGCATCCAGAAGATGCTGAATTTGAACAGAAGATCAACCGACTTATGGCTGCAAAACAGAAACTTA
GACAGTTACAAGATCTTGTTGCTATGGTACAGGATGATGATGCAGCTCAAGGAGTTATCTCTGCCAGTGCATCAAATTTGGATGATTTCT
ACCCAGCAGAAGAAGACACCAAGCAAAATTCAAATAACACTAGAGGAAATGCCAATAAAACACAGAAAGATACTGGAGTAAATGAAAAGG
CAAGAGAGAAATTTTATGAGGCTAAACTACAGCAGCAACAGAGAGAGCTAAAACAATTGCAGGAAGAAAGAAAGAAACTGATTGACATTC
AGGAGAAAATTCAAGCATTGCAAACGGCATGCCCTGACTTACAGCTGTCAGCTGCTAGTGTGGGTAACTGTCCCACCAAAAAATATATGC
CAGCTGTTACTTCAACCCCAACTGTTAATCAACACGAGACCAGTACAAGCAAATCTGTTTTTGAGCCTGAAGATTCTTCAATAGTAGATA
ATGAGTTGTGGTCAGAAATGAGAAGACATGAAATGTTGAGGGAGGAGCTGCGACAGAGAAGAAAGCAGCTTGAAGCTCTGATGGCTGAAC
ATCAGAGGAGGCAAGGTCTAGCTGAAACTGCATCTCCAGTGGCTGTGTCATTGAGAAGTGATGGATCTGAGAACCTATGTACTCCTCAGC
AAAGTAGAACAGAAAAAACGATGGCAACTTGGGGAGGGTCTACCCAGTGTGCACTAGATGAAGAAGGAGATGAAGACGGTTACCTTTCTG
AAGGAATTGTTCGGACAGATGAAGAGGAGGAAGAAGAGCAAGATGCCAGTTCCAATGATAACTTTTCTGTGTGTCCTTCTAACAGTGTGA
ATCATAACTCCTACAATGGAAAGGAAACTAAAAATAGGTGGAAGAACAATTGCCCTTTTTCGGCAGATGAAAATTATCGTCCTTTAGCCA
AGACAAGGCAACAGAATATCAGCATGCAACGGCAAGAAAACCTTCGTTGGGTGTCAGAGCTCTCTTACGTAGAAGAGAAAGAACAATGGC
AAGAACAAATCAATCAGCTAAAGAAACAGCTTGATTTTAGTGTCAGTATTTGTCAGACTTTGATGCAAGACCAGCAGACTCTATCTTGTC
TGCTACAAACTCTTCTCACGGGTCCTTACAGTGTTATGCCCAGCAATGTTGCATCTCCTCAAGTACACTTCATAATGCACCAGTTGAACC
AGTGCTATACTCAGCTAACATGGCAACAGAATAATGTTCAGAGGTTGAAACAAATGCTAAATGAACTTATGCGCCAGCAAAATCAGCATC
CAGAAAAACCTGGAGGCAAGGAAAGAGGCAGTAGTGCATCGCACCCTCCTTCTCCCAGTTTATTTTGTCCTTTCAGCTTTCCAACACAGC
CTGTAAATCTCTTCAATATACCTGGATTTACTAACTTTTCATCATTTGCACCAGGTATGAATTTCAGCCCTTTATTTCCTTCTAATTTTG
GAGATTTTTCTCAGAATATCTCTACACCCAGTGAACAGCAGCAACCCTTAGCCCAGAATTCTTCAGGAAAAACAGAATATATGGCTTTTC
CAAAACCTTTTGAAAGCAGTTCCTCTATTGGAGCAGAGAAACCAAGGAATAAAAAACTGCCTGAAGAGGAGGTGGAAAGCAGTAGGACAC
CATGGTTATATGAACAAGAAGGTGAAGTAGAGAAACCATTTATCAAGACTGGATTTTCAGTGTCTGTAGAAAAATCTACAAGTAGTAACC
GCAAAAATCAATTAGATACAAACGGAAGAAGACGCCAGTTTGATGAAGAATCACTGGAAAGCTTTAGCAGTATGCCTGATCCAGTAGATC
CAACAACAGTGACTAAAACATTCAAGACAAGAAAAGCGTCTGCACAGGCCAGCCTGGCATCTAAAGATAAAACTCCCAAGTCAAAAAGTA
AGAAGAGGAATTCTACTCAGCTGAAAAGCAGAGTTAAAAACATCAAAACTGGGAGTGATTTTTCCATGTTTGAAGCTTTGCGAGATACTA
TTTATTCTGAAGTAGCTACATTAATTTCTCAAAATGAATCTCGTCCACATTTTCTTATTGAACTCTTCCATGAGCTGCAGCTACTAAACA
CAGACTACTTGAGACAGAGGGCTTTATATGCATTGCAGGACATAGTATCCAGACATATTTCTGAGAGCCATGAAAAAGGAGAAAATGTAA
AGTCAGTAAACTCTGGTACTTGGATAGCATCAAACTCAGAACTTACTCCTAGTGAGAGCCTTGCTACTACTGATGATGAAACTTTTGAGA
AGAACTTTGAAAGAGAAACCCATAAAATAAGTGAGCAAAATGATGCTGATAATGCTAGTGTCCTGTCTGTATCATCAAATTTTGAGCCTT
TTGCAACAGATGATCTAGGTAACACCGTGATTCACTTAGATCAAGCATTAGCCAGAATGAGAGAATATGAGCGTATGAAGACTGAGGCTG
AAAGTAACTCAAATATGAGATGCACCTGCAGGATTATTGAGGATGGAGATGGTGCTGGTGCAGGTACTACAGTTAATAATTTAGAAGAAA
CTCCCGTTATTGAAAATCGTAGTTCACAACAACCTGTAAGTGAAGTTTCTACCATCCCATGTCCTAGAATTGATACTCAGCAGCTGGACC
GGCAAATTAAAGCAATTATGAAAGAAGTCATTCCTTTTTTGAAGGAGGATCCAAAGTGGGAATTCCCTCGGAAGAACTTGGTTCTTGGAA
AAACTCTAGGAGAAGGCGAATTTGGAAAAGTGGTCAAGGCAACGGCCTTCCATCTGAAAGGCAGAGCAGGGTACACCACGGTGGCCGTGA
AGATGCTGAAAGAGAACGCCTCCCCGAGTGAGCTGCGAGACCTGCTGTCAGAGTTCAACGTCCTGAAGCAGGTCAACCACCCACATGTCA
TCAAATTGTATGGGGCCTGCAGCCAGGATGGCCCGCTCCTCCTCATCGTGGAGTACGCCAAATACGGCTCCCTGCGGGGCTTCCTCCGCG
AGAGCCGCAAAGTGGGGCCTGGCTACCTGGGCAGTGGAGGCAGCCGCAACTCCAGCTCCCTGGACCACCCGGATGAGCGGGCCCTCACCA
TGGGCGACCTCATCTCATTTGCCTGGCAGATCTCACAGGGGATGCAGTATCTGGCCGAGATGAAGCTCGTTCATCGGGACTTGGCAGCCA
GAAACATCCTGGTAGCTGAGGGGCGGAAGATGAAGATTTCGGATTTCGGCTTGTCCCGAGATGTTTATGAAGAGGATTCCTACGTGAAGA
GGAGCCAGGGTCGGATTCCAGTTAAATGGATGGCAATTGAATCCCTTTTTGATCATATCTACACCACGCAAAGTGATGTATGGTCTTTTG
GTGTCCTGCTGTGGGAGATCGTGACCCTAGGGGGAAACCCCTATCCTGGGATTCCTCCTGAGCGGCTCTTCAACCTTCTGAAGACCGGCC
ACCGGATGGAGAGGCCAGACAACTGCAGCGAGGAGATGTACCGCCTGATGCTGCAATGCTGGAAGCAGGAGCCGGACAAAAGGCCGGTGT
TTGCGGACATCAGCAAAGACCTGGAGAAGATGATGGTTAAGAGGAGAGACTACTTGGACCTTGCGGCGTCCACTCCATCTGACTCCCTGA
TTTATGACGACGGCCTCTCAGAGGAGGAGACACCGCTGGTGGACTGTAATAATGCCCCCCTCCCTCGAGCCCTCCCTTCCACATGGATTG
AAAACAAACTCTATGGCATGTCAGACCCGAACTGGCCTGGAGAGAGTCCTGTACCACTCACGAGAGCTGATGGCACTAACACTGGGTTTC
CAAGATATCCAAATGATAGTGTATATGCTAACTGGATGCTTTCACCCTCAGCGGCAAAATTAATGGACACGTTTGATAGTTAACATTTCT
TTGTGAAAGGTAATGGACTCACAAGGGGAAGAAACATGCTGAGAATGGAAAGTCTACCGGCCCTTTCTTTGTGAACGTCACATTGGCCGA
GCCGTGTTCAGTTCCCAGGTGGCAGACTCGTTTTTGGTAGTTTGTTTTAACTTCCAAGGTGGTTTTACTTCTGATAGCCGGTGATTTTCC
CTCCTAGCAGACATGCCACACCGGGTAAGAGCTCTGAGTCTTAGTGGTTAAGCATTCCTTTCTCTTCAGTGCCCAGCAGCACCCAGTGTT
GGTCTGTGTCCATCAGTGACCACCAACATTCTGTGTTCACATGTGTGGGTCCAACACTTACTACCTGGTGTATGAAATTGGACCTGAACT
GTTGGATTTTTCTAGTTGCCGCCAAACAAGGCAAAAAAATTTAAACATGAAGCACACACACAAAAAAGGCAGTAGGAAAAATGCTGGCCC
TGATGACCTGTCCTTATTCAGAATGAGAGACTGCGGGGGGGGCCTGGGGGTAGTGTCAATGCCCCTCCAGGGCTGGAGGGGAAGAGGGGC
CCCGAGGATGGGCCTGGGCTCAGCATTCGAGATCTTGAGAATGATTTTTTTTAAATCATGCAACCTTTCCTTAGGAAGACATTTGGTTTT
CATCATGATTAAGATGATTCCTAGATTTAGCACAATGGAGAGATTCCATGCCATCTTTACTATGTGGATGGTGGTATCAGGGAAGAGGGC
TCACAAGACACATTTGTCCCCCGGGCCCACCACATCATCCTCACGTGTTCGGTACTGAGCAGCCACTACCCCTGATGAGAACAGTATGAA
GAAAGGGGGCTGTTGGAGTCCCAGAATTGCTGACAGCAGAGGCTTTGCTGCTGTGAATCCCACCTGCCACCAGCCTGCAGCACACCCCAC
AGCCAAGTAGAGGCGAAAGCAGTGGCTCATCCTACCTGTTAGGAGCAGGTAGGGCTTGTACTCACTTTAATTTGAATCTTATCAACTTAC
TCATAAAGGGACAGGCTAGCTAGCTGTGTTAGAAGTAGCAATGACAATGACCAAGGACTGCTACACCTCTGATTACAATTCTGATGTGAA
AAAGATGGTGTTTGGCTCTTATAGAGCCTGTGTGAAAGGCCCATGGATCAGCTCTTCCTGTGTTTGTAATTTAATGCTGCTACAAGATGT
TTCTGTTTCTTAGATTCTGACCATGACTCATAAGCTTCTTGTCATTCTTCATTGCTTGTTTGTGGTCACAGATGCACAACACTCCTCCAG
TCTTGTGGGGGCAGCTTTTGGGAAGTCTCAGCAGCTCTTCTGGCTGTGTTGTCAGCACTGTAACTTCGCAGAAAAGAGTCGGATTACCAA
AACACTGCCTGCTCTTCAGACTTAAAGCACTGATAGGACTTAAAATAGTCTCATTCAAATACTGTATTTTATATAGGCATTTCACAAAAA
CAGCAAAATTGTGGCATTTTGTGAGGCCAAGGCTTGGATGCGTGTGTAATAGAGCCTTGTGGTGTGTGCGCACACACCCAGAGGGAGAGT
TTGAAAAATGCTTATTGGACACGTAACCTGGCTCTAATTTGGGCTGTTTTTCAGATACACTGTGATAAGTTCTTTTACAAATATCTATAG
ACATGGTAAACTTTTGGTTTTCAGATATGCTTAATGATAGTCTTACTAAATGCAGAAATAAGAATAAACTTTCTCAAATTATTAAAAATG
CCTACACAGTAAGTGTGAATTGCTGCAACAGGTTTGTTCTCAGGAGGGTAAGAACTCCAGGTCTAAACAGCTGACCCAGTGATGGGGAAT
TTATCCTTGACCAATTTATCCTTGACCAATAACCTAATTGTCTATTCCTGAGTTATAAAAGTCCCCATCCTTATTAGCTCTACTGGAATT
TTCATACACGTAAATGCAGAAGTTACTAAGTATTAAGTATTACTGAGTATTAAGTAGTAATCTGTCAGTTATTAAAATTTGTAAAATCTA
TTTATGAAAGGTCATTAAACCAGATCATGTTCCTTTTTTTGTAATCAAGGTGACTAAGAAAATCAGTTGTGTAAATAAAATCATGTATCA

>63341_63341_16_PCM1-RET_PCM1_chr8_17851129_ENST00000524226_RET_chr10_43612030_ENST00000355710_length(amino acids)=1957AA_BP=1555
MATGGGPFEDGMNDQDLPNWSNENVDDRLNNMDWGAQQKKANRSSEKNKKKFGVESDKRVTNDISPESSPGVGRRRTKTPHTFPHSRYMS
QMSVPEQAELEKLKQRINFSDLDQRSIGSDSQGRATAANNKRQLSENRKPFNFLPMQINTNKSKDASTNPPNRETIGSAQCKELFASALS
NDLLQNCQVSEEDGRGEPAMESSQIVSRLVQIRDYITKASSMREDLVEKNERSANVERLTHLIDHLKEQEKSYMKFLKKILARDPQQEPM
EEIENLKKQHDLLKRMLQQQEQLRALQGRQAALLALQHKAEQAIAVMDDSVVAETAGSLSGVSITSELNEELNDLIQRFHNQLRDSQPPA
VPDNRRQAESLSLTREVSQSRKPSASERLPDEKVELFSKMRVLQEKKQKMDKLLGELHTLRDQHLNNSSSSPQRSVDQRSTSAPSASVGL
APVVNGESNSLTSSVPYPTASLVSQNESENEGHLNPSEKLQKLNEVRKRLNELRELVHYYEQTSDMMTDAVNENRKDEETEESEYDSEHE
NSEPVTNIRNPQVASTWNEVNSHSNAQCVSNNRDGRTVNSNCEINNRSAANIRALNMPPSLADCRYNREGEQEIHVAQGEDDEEEEEEAE
EEGVSGASLSSHRSSLVDEHPEDAEFEQKINRLMAAKQKLRQLQDLVAMVQDDDAAQGVISASASNLDDFYPAEEDTKQNSNNTRGNANK
TQKDTGVNEKAREKFYEAKLQQQQRELKQLQEERKKLIDIQEKIQALQTACPDLQLSAASVGNCPTKKYMPAVTSTPTVNQHETSTSKSV
FEPEDSSIVDNELWSEMRRHEMLREELRQRRKQLEALMAEHQRRQGLAETASPVAVSLRSDGSENLCTPQQSRTEKTMATWGGSTQCALD
EEGDEDGYLSEGIVRTDEEEEEEQDASSNDNFSVCPSNSVNHNSYNGKETKNRWKNNCPFSADENYRPLAKTRQQNISMQRQENLRWVSE
LSYVEEKEQWQEQINQLKKQLDFSVSICQTLMQDQQTLSCLLQTLLTGPYSVMPSNVASPQVHFIMHQLNQCYTQLTWQQNNVQRLKQML
NELMRQQNQHPEKPGGKERGSSASHPPSPSLFCPFSFPTQPVNLFNIPGFTNFSSFAPGMNFSPLFPSNFGDFSQNISTPSEQQQPLAQN
SSGKTEYMAFPKPFESSSSIGAEKPRNKKLPEEEVESSRTPWLYEQEGEVEKPFIKTGFSVSVEKSTSSNRKNQLDTNGRRRQFDEESLE
SFSSMPDPVDPTTVTKTFKTRKASAQASLASKDKTPKSKSKKRNSTQLKSRVKNIKTGSDFSMFEALRDTIYSEVATLISQNESRPHFLI
ELFHELQLLNTDYLRQRALYALQDIVSRHISESHEKGENVKSVNSGTWIASNSELTPSESLATTDDETFEKNFERETHKISEQNDADNAS
VLSVSSNFEPFATDDLGNTVIHLDQALARMREYERMKTEAESNSNMRCTCRIIEDGDGAGAGTTVNNLEETPVIENRSSQQPVSEVSTIP
CPRIDTQQLDRQIKAIMKEVIPFLKEDPKWEFPRKNLVLGKTLGEGEFGKVVKATAFHLKGRAGYTTVAVKMLKENASPSELRDLLSEFN
VLKQVNHPHVIKLYGACSQDGPLLLIVEYAKYGSLRGFLRESRKVGPGYLGSGGSRNSSSLDHPDERALTMGDLISFAWQISQGMQYLAE
MKLVHRDLAARNILVAEGRKMKISDFGLSRDVYEEDSYVKRSQGRIPVKWMAIESLFDHIYTTQSDVWSFGVLLWEIVTLGGNPYPGIPP
ERLFNLLKTGHRMERPDNCSEEMYRLMLQCWKQEPDKRPVFADISKDLEKMMVKRRDYLDLAASTPSDSLIYDDGLSEEETPLVDCNNAP

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Fusion Gene PPI Analysis for PCM1-RET


check button Go to ChiPPI (Chimeric Protein-Protein interactions) to see the chimeric PPI interaction in

ChiPPI page.


check button Protein-protein interactors with each fusion partner protein in wild-type (BIOGRID-3.4.160)
HgeneHgene's interactorsTgeneTgene's interactors


check button - Retained PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenStill interaction with


check button - Lost PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with
HgenePCM1chr8:17851129chr10:43612030ENST00000325083+29391913_20241609.02025.0BBS4
HgenePCM1chr8:17851129chr10:43612030ENST00000325083+29391279_17991609.02025.0HAP1


check button - Retained PPIs, but lost function due to frame-shift fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


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Related Drugs for PCM1-RET


check button Drugs targeting genes involved in this fusion gene.
(DrugBank Version 5.1.8 2021-05-08)
PartnerGeneUniProtAccDrugBank IDDrug nameDrug activityDrug typeDrug status

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Related Diseases for PCM1-RET


check button Diseases associated with fusion partners.
(DisGeNet 4.0)
PartnerGeneDisease IDDisease name# pubmedsSource