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Center for Computational Systems Medicine
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Fusion Gene Summary

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Fusion Gene ORF analysis

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Fusion Genomic Features

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Fusion Protein Features

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Fusion Gene Sequence

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Fusion Gene PPI analysis

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Related Drugs

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Related Diseases

Fusion gene:PCNXL2-CDCA7 (FusionGDB2 ID:63461)

Fusion Gene Summary for PCNXL2-CDCA7

check button Fusion gene summary
Fusion gene informationFusion gene name: PCNXL2-CDCA7
Fusion gene ID: 63461
HgeneTgene
Gene symbol

PCNXL2

CDCA7

Gene ID

80003

83879

Gene namepecanex 2cell division cycle associated 7
SynonymsPCNXL2ICF3|JPO1
Cytomap

1q42.2

2q31.1

Type of geneprotein-codingprotein-coding
Descriptionpecanex-like protein 2pecanex homolog 2cell division cycle-associated protein 7c-Myc target JPO1
Modification date2020031320200329
UniProtAcc.

Q96GN5

Ensembl transtripts involved in fusion geneENST00000430153, ENST00000258229, 
ENST00000344698, ENST00000488780, 
ENST00000520463, 		ENST00000306721, 
ENST00000347703, ENST00000392567, 
ENST00000410019, ENST00000410101, 
Fusion gene scores* DoF score5 X 5 X 3=754 X 3 X 3=36
# samples 54
** MAII scorelog2(5/75*10)=-0.584962500721156
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0		log2(4/36*10)=0.15200309344505
effective Gene in Pan-Cancer Fusion Genes (eGinPCFGs).
DoF>8 and MAII>0
Context

PubMed: PCNXL2 [Title/Abstract] AND CDCA7 [Title/Abstract] AND fusion [Title/Abstract]

Most frequent breakpointPCNXL2(233372591)-CDCA7(174227954), # samples:1
Anticipated loss of major functional domain due to fusion event.
* DoF score (Degree of Frequency) = # partners X # break points X # cancer types
** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10)

check button Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez
PartnerGeneGO IDGO termPubMed ID
TgeneCDCA7

GO:0042127

regulation of cell proliferation

11598121


check buttonFusion gene breakpoints across PCNXL2 (5'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.
all structure

check buttonFusion gene breakpoints across CDCA7 (3'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.
all structure

check button Fusion gene information from two resources (ChiTars 5.0 and ChimerDB 4.0)
* All genome coordinats were lifted-over on hg19.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
SourceDiseaseSampleHgeneHchrHbpHstrandTgeneTchrTbpTstrand
ChimerDB4PRADTCGA-G9-6364-01APCNXL2chr1

233372591

-CDCA7chr2

174227954

+


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Fusion Gene ORF analysis for PCNXL2-CDCA7

check button Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
ORFHenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrand
Frame-shiftENST00000430153ENST00000306721PCNXL2chr1

233372591

-CDCA7chr2

174227954

+
Frame-shiftENST00000430153ENST00000347703PCNXL2chr1

233372591

-CDCA7chr2

174227954

+
Frame-shiftENST00000430153ENST00000392567PCNXL2chr1

233372591

-CDCA7chr2

174227954

+
Frame-shiftENST00000430153ENST00000410019PCNXL2chr1

233372591

-CDCA7chr2

174227954

+
Frame-shiftENST00000430153ENST00000410101PCNXL2chr1

233372591

-CDCA7chr2

174227954

+
In-frameENST00000258229ENST00000306721PCNXL2chr1

233372591

-CDCA7chr2

174227954

+
In-frameENST00000258229ENST00000347703PCNXL2chr1

233372591

-CDCA7chr2

174227954

+
In-frameENST00000258229ENST00000392567PCNXL2chr1

233372591

-CDCA7chr2

174227954

+
In-frameENST00000258229ENST00000410019PCNXL2chr1

233372591

-CDCA7chr2

174227954

+
In-frameENST00000258229ENST00000410101PCNXL2chr1

233372591

-CDCA7chr2

174227954

+
intron-3CDSENST00000344698ENST00000306721PCNXL2chr1

233372591

-CDCA7chr2

174227954

+
intron-3CDSENST00000344698ENST00000347703PCNXL2chr1

233372591

-CDCA7chr2

174227954

+
intron-3CDSENST00000344698ENST00000392567PCNXL2chr1

233372591

-CDCA7chr2

174227954

+
intron-3CDSENST00000344698ENST00000410019PCNXL2chr1

233372591

-CDCA7chr2

174227954

+
intron-3CDSENST00000344698ENST00000410101PCNXL2chr1

233372591

-CDCA7chr2

174227954

+
intron-3CDSENST00000488780ENST00000306721PCNXL2chr1

233372591

-CDCA7chr2

174227954

+
intron-3CDSENST00000488780ENST00000347703PCNXL2chr1

233372591

-CDCA7chr2

174227954

+
intron-3CDSENST00000488780ENST00000392567PCNXL2chr1

233372591

-CDCA7chr2

174227954

+
intron-3CDSENST00000488780ENST00000410019PCNXL2chr1

233372591

-CDCA7chr2

174227954

+
intron-3CDSENST00000488780ENST00000410101PCNXL2chr1

233372591

-CDCA7chr2

174227954

+
intron-3CDSENST00000520463ENST00000306721PCNXL2chr1

233372591

-CDCA7chr2

174227954

+
intron-3CDSENST00000520463ENST00000347703PCNXL2chr1

233372591

-CDCA7chr2

174227954

+
intron-3CDSENST00000520463ENST00000392567PCNXL2chr1

233372591

-CDCA7chr2

174227954

+
intron-3CDSENST00000520463ENST00000410019PCNXL2chr1

233372591

-CDCA7chr2

174227954

+
intron-3CDSENST00000520463ENST00000410101PCNXL2chr1

233372591

-CDCA7chr2

174227954

+

check buttonORFfinder result based on the fusion transcript sequence of in-frame fusion genes.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandSeq length
(transcript)		BP loci
(transcript)		Predicted start
(transcript)		Predicted stop
(transcript)		Seq length
(amino acids)
ENST00000258229PCNXL2chr1233372591-ENST00000347703CDCA7chr2174227954+480225931035611183
ENST00000258229PCNXL2chr1233372591-ENST00000392567CDCA7chr2174227954+473925931034111133
ENST00000258229PCNXL2chr1233372591-ENST00000306721CDCA7chr2174227954+489525931035611183
ENST00000258229PCNXL2chr1233372591-ENST00000410101CDCA7chr2174227954+361825931035611183
ENST00000258229PCNXL2chr1233372591-ENST00000410019CDCA7chr2174227954+396825931035611183

check buttonDeepORF prediction of the coding potential based on the fusion transcript sequence of in-frame fusion genes. DeepORF is a coding potential classifier based on convolutional neural network by comparing the real Ribo-seq data. If the no-coding score < 0.5 and coding score > 0.5, then the in-frame fusion transcript is predicted as being likely translated.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandNo-coding scoreCoding score
ENST00000258229ENST00000347703PCNXL2chr1233372591-CDCA7chr2174227954+0.0006696860.9993304
ENST00000258229ENST00000392567PCNXL2chr1233372591-CDCA7chr2174227954+0.0003916240.99960846
ENST00000258229ENST00000306721PCNXL2chr1233372591-CDCA7chr2174227954+0.0005992290.99940073
ENST00000258229ENST00000410101PCNXL2chr1233372591-CDCA7chr2174227954+0.0015326020.9984674
ENST00000258229ENST00000410019PCNXL2chr1233372591-CDCA7chr2174227954+0.0014446510.99855536

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Fusion Genomic Features for PCNXL2-CDCA7


check buttonFusionAI prediction of the potential fusion gene breakpoint based on the pre-mature RNA sequence context (+/- 5kb of individual partner genes, total 20kb length sequence). FusionAI is a fusion gene breakpoint classifier based on convolutional neural network by comparing the fusion positive and negative sequence context of ~ 20K fusion gene data. From here, we can have the relative potentency of the 20K genomic sequence how individual sequnce will be likely used as the gene fusion breakpoints.
HgeneHchrHbpHstrandTgeneTchrTbpTstrand1-pp (fusion gene breakpoint)
PCNXL2chr1233372590-CDCA7chr2174227953+5.88E-070.9999994
PCNXL2chr1233372590-CDCA7chr2174227953+5.88E-070.9999994

check buttonDistribution of 44 human genomic features loci across 20kb length fusion breakpoint regions. We integrated a total of 44 different types of human genomic feature loci information across five big categories including virus integration sites, repeats, structural variants, chromatin states, and gene expression regulation. More details are in help page.
genomic feature

check buttonDistribution of 44 human genomic features loci across 20kb length fusion breakpoint regions that are ovelapped with the top 1% feature importance score regions. More details are in help page.
genomic feature of top 1%

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Fusion Protein Features for PCNXL2-CDCA7


check button Four levels of functional features of fusion genes
Go to FGviewer search page for the most frequent breakpoint (https://ccsmweb.uth.edu/FGviewer/chr1:233372591/chr2:174227954)
- FGviewer provides the online visualization of the retention search of the protein functional features across DNA, RNA, protein, and pathological levels.
- How to search
1. Put your fusion gene symbol.
2. Press the tab key until there will be shown the breakpoint information filled.
4. Go down and press 'Search' tab twice.
4. Go down to have the hyperlink of the search result.
5. Click the hyperlink.
6. See the FGviewer result for your fusion gene.
FGviewer

check buttonMain function of each fusion partner protein. (from UniProt)
HgeneTgene
.CDCA7

Q96GN5

FUNCTION: Transcriptional activator which is required for calcium-dependent dendritic growth and branching in cortical neurons. Recruits CREB-binding protein (CREBBP) to nuclear bodies. Component of the CREST-BRG1 complex, a multiprotein complex that regulates promoter activation by orchestrating a calcium-dependent release of a repressor complex and a recruitment of an activator complex. In resting neurons, transcription of the c-FOS promoter is inhibited by BRG1-dependent recruitment of a phospho-RB1-HDAC1 repressor complex. Upon calcium influx, RB1 is dephosphorylated by calcineurin, which leads to release of the repressor complex. At the same time, there is increased recruitment of CREBBP to the promoter by a CREST-dependent mechanism, which leads to transcriptional activation. The CREST-BRG1 complex also binds to the NR2B promoter, and activity-dependent induction of NR2B expression involves a release of HDAC1 and recruitment of CREBBP (By similarity). {ECO:0000250}.FUNCTION: Plays a role in transcriptional regulation as a repressor that inhibits monoamine oxidase A (MAOA) activity and gene expression by binding to the promoter. Plays an important oncogenic role in mediating the full transforming effect of MYC in medulloblastoma cells. Involved in apoptotic signaling pathways; May act downstream of P38-kinase and BCL-2, but upstream of CASP3/caspase-3 as well as CCND1/cyclin D1 and E2F1. {ECO:0000269|PubMed:15654081, ECO:0000269|PubMed:15994933, ECO:0000269|PubMed:16829576}.

check buttonRetention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at

download page


* Minus value of BPloci means that the break pointn is located before the CDS.
- In-frame and retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
HgenePCNXL2chr1:233372591chr2:174227954ENST00000258229-93434_547862138.0TransmembraneHelical
HgenePCNXL2chr1:233372591chr2:174227954ENST00000258229-93457_777862138.0TransmembraneHelical
HgenePCNXL2chr1:233372591chr2:174227954ENST00000430153-91434_5485287.0TransmembraneHelical
HgenePCNXL2chr1:233372591chr2:174227954ENST00000430153-91457_7785287.0TransmembraneHelical
TgeneCDCA7chr1:233372591chr2:174227954ENST00000306721210157_186128451.0Compositional biasNote=Arg-rich
TgeneCDCA7chr1:233372591chr2:174227954ENST0000034770319157_18649372.0Compositional biasNote=Arg-rich
TgeneCDCA7chr1:233372591chr2:174227954ENST0000039256718157_18649322.0Compositional biasNote=Arg-rich
TgeneCDCA7chr1:233372591chr2:174227954ENST00000306721210160_176128451.0MotifNuclear localization signal
TgeneCDCA7chr1:233372591chr2:174227954ENST0000034770319160_17649372.0MotifNuclear localization signal
TgeneCDCA7chr1:233372591chr2:174227954ENST0000039256718160_17649322.0MotifNuclear localization signal
TgeneCDCA7chr1:233372591chr2:174227954ENST00000306721210247_371128451.0RegionNote=Mediates transcriptional activity
TgeneCDCA7chr1:233372591chr2:174227954ENST0000034770319247_37149372.0RegionNote=Mediates transcriptional activity
TgeneCDCA7chr1:233372591chr2:174227954ENST0000039256718247_37149322.0RegionNote=Mediates transcriptional activity

- In-frame and not-retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
HgenePCNXL2chr1:233372591chr2:174227954ENST00000258229-9341937_20637862138.0Compositional biasNote=Ser-rich
HgenePCNXL2chr1:233372591chr2:174227954ENST00000344698-1101937_20630778.0Compositional biasNote=Ser-rich
HgenePCNXL2chr1:233372591chr2:174227954ENST00000430153-9141937_206385287.0Compositional biasNote=Ser-rich
HgenePCNXL2chr1:233372591chr2:174227954ENST00000258229-9341029_10497862138.0TransmembraneHelical
HgenePCNXL2chr1:233372591chr2:174227954ENST00000258229-9341099_11197862138.0TransmembraneHelical
HgenePCNXL2chr1:233372591chr2:174227954ENST00000258229-9341124_11447862138.0TransmembraneHelical
HgenePCNXL2chr1:233372591chr2:174227954ENST00000258229-9341193_12137862138.0TransmembraneHelical
HgenePCNXL2chr1:233372591chr2:174227954ENST00000258229-9341237_12577862138.0TransmembraneHelical
HgenePCNXL2chr1:233372591chr2:174227954ENST00000258229-9341265_12857862138.0TransmembraneHelical
HgenePCNXL2chr1:233372591chr2:174227954ENST00000258229-9341302_13227862138.0TransmembraneHelical
HgenePCNXL2chr1:233372591chr2:174227954ENST00000258229-9341324_13447862138.0TransmembraneHelical
HgenePCNXL2chr1:233372591chr2:174227954ENST00000258229-934844_8647862138.0TransmembraneHelical
HgenePCNXL2chr1:233372591chr2:174227954ENST00000258229-934868_8887862138.0TransmembraneHelical
HgenePCNXL2chr1:233372591chr2:174227954ENST00000258229-934901_9217862138.0TransmembraneHelical
HgenePCNXL2chr1:233372591chr2:174227954ENST00000258229-934952_9727862138.0TransmembraneHelical
HgenePCNXL2chr1:233372591chr2:174227954ENST00000258229-934983_10037862138.0TransmembraneHelical
HgenePCNXL2chr1:233372591chr2:174227954ENST00000344698-1101029_10490778.0TransmembraneHelical
HgenePCNXL2chr1:233372591chr2:174227954ENST00000344698-1101099_11190778.0TransmembraneHelical
HgenePCNXL2chr1:233372591chr2:174227954ENST00000344698-1101124_11440778.0TransmembraneHelical
HgenePCNXL2chr1:233372591chr2:174227954ENST00000344698-1101193_12130778.0TransmembraneHelical
HgenePCNXL2chr1:233372591chr2:174227954ENST00000344698-1101237_12570778.0TransmembraneHelical
HgenePCNXL2chr1:233372591chr2:174227954ENST00000344698-1101265_12850778.0TransmembraneHelical
HgenePCNXL2chr1:233372591chr2:174227954ENST00000344698-1101302_13220778.0TransmembraneHelical
HgenePCNXL2chr1:233372591chr2:174227954ENST00000344698-1101324_13440778.0TransmembraneHelical
HgenePCNXL2chr1:233372591chr2:174227954ENST00000344698-11034_540778.0TransmembraneHelical
HgenePCNXL2chr1:233372591chr2:174227954ENST00000344698-11057_770778.0TransmembraneHelical
HgenePCNXL2chr1:233372591chr2:174227954ENST00000344698-110844_8640778.0TransmembraneHelical
HgenePCNXL2chr1:233372591chr2:174227954ENST00000344698-110868_8880778.0TransmembraneHelical
HgenePCNXL2chr1:233372591chr2:174227954ENST00000344698-110901_9210778.0TransmembraneHelical
HgenePCNXL2chr1:233372591chr2:174227954ENST00000344698-110952_9720778.0TransmembraneHelical
HgenePCNXL2chr1:233372591chr2:174227954ENST00000344698-110983_10030778.0TransmembraneHelical
HgenePCNXL2chr1:233372591chr2:174227954ENST00000430153-9141029_104985287.0TransmembraneHelical
HgenePCNXL2chr1:233372591chr2:174227954ENST00000430153-9141099_111985287.0TransmembraneHelical
HgenePCNXL2chr1:233372591chr2:174227954ENST00000430153-9141124_114485287.0TransmembraneHelical
HgenePCNXL2chr1:233372591chr2:174227954ENST00000430153-9141193_121385287.0TransmembraneHelical
HgenePCNXL2chr1:233372591chr2:174227954ENST00000430153-9141237_125785287.0TransmembraneHelical
HgenePCNXL2chr1:233372591chr2:174227954ENST00000430153-9141265_128585287.0TransmembraneHelical
HgenePCNXL2chr1:233372591chr2:174227954ENST00000430153-9141302_132285287.0TransmembraneHelical
HgenePCNXL2chr1:233372591chr2:174227954ENST00000430153-9141324_134485287.0TransmembraneHelical
HgenePCNXL2chr1:233372591chr2:174227954ENST00000430153-914844_86485287.0TransmembraneHelical
HgenePCNXL2chr1:233372591chr2:174227954ENST00000430153-914868_88885287.0TransmembraneHelical
HgenePCNXL2chr1:233372591chr2:174227954ENST00000430153-914901_92185287.0TransmembraneHelical
HgenePCNXL2chr1:233372591chr2:174227954ENST00000430153-914952_97285287.0TransmembraneHelical
HgenePCNXL2chr1:233372591chr2:174227954ENST00000430153-914983_100385287.0TransmembraneHelical


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Fusion Gene Sequence for PCNXL2-CDCA7


check button For in-frame fusion transcripts, we provide the fusion transcript sequences and fusion amino acid sequences. To have fusion amino acid sequence, we ran ORFfinder and chose the longest ORF among the all predicted ones.
>63461_63461_1_PCNXL2-CDCA7_PCNXL2_chr1_233372591_ENST00000258229_CDCA7_chr2_174227954_ENST00000306721_length(transcript)=4895nt_BP=2593nt
TGGCGCTCACCTGCCCGGCCGCAGCAGCCGGCTCCGGCGCCGCGGTTCGCGGGTCCGGGCGGAAGAGCAGCTCCAGCTTCAAACGTGGGG
TGGAAGGAGGCGGCGGGGGCGACGGCGGCGGCGACGGCGGGGGCGCGGCCCGCGGGCCCGGGTGTTAGACCTGAGGGAGCCTGGAGATCC
GGCCGGGGCGCGCAGGGTGCAGCGGGGCGCTCACCAGCCCCGGGGCGCAGCCGGCATGGTGTCCCAGGTGCTGCAGCTGCTCCGGCAGGG
CGTGTGGGCCGCGCTCACCGGGGGCTGGTACCACGACCCGGAGCAGAGCAAGTTCACCAACAGCTGCCACCTCTACCTGTGGCTGTTCCT
CCTGCTGCTGCCCCTGGCCCTGCACCTGGCTTTTCCTCCAAATGCGATCATTGTATTTTTCTACTGCAGTGCAGTGACTATATTCTTCAC
AATAATCAAACTGGTCAGTTATCGCCTACACCTCATGTTTGACAAAGGAGAAGTAATTCAGCAAAAGCCCTCCAGAAAGGAAGAAAAGCC
AAATAAAGACAAGGAGGCCAAAGGTGAACACATAACTAATCACAGAAATCCAAGCAATAATAGGCAGATTCACAATGGCAAAAAGGAAGA
GGCCAGTCGAAACCTCTCCACGCCTCCCCTCCGCTGCAGCTCCAGAGGGCAAAGCATAACCTCTCATCACTCTTCTGGGCCATTGGAGTT
GTCAGCACAGGAAACTGTAGAAGATCTCAAAGGTGTCATTCTATTAGAAGACCATCCCATAGCACCAGTGTCATCTACCTCACCTGGTAT
CAAAGTGGAAAGCTTACCTGCGTCTCAAGCACACATGCTGGAAACCACGACCAAGTCAGTAATACCTGTAAAACCAGTTGCCACAGAAAC
TCTCATCAATGGTAAAGGAAAGGAAAGAGGAGGCAAGGGGCAGCCTCCTTTGCGCCACAGATCCGAGGGTGGCTTAGTGGATAAGGGACC
CTTGAAGAAGTTGCCCCACCTGTCTTTGTCTCAGTATGACTTACTAGAAACAGACGTTTCTTTCCAGCCGTGGGGGAGTGAGAATTCAGT
CCTGATTCCAGAACCTGTCAGTTGTCCCCGGGGCTCCATAAGGGAACGGGTACAAAGCAAGTCACCTCAGGACAGCCTGAGCAGCAGCTG
CCCTCAATGTGACACCATCGTGGCCAAGCCTGTGGAGGAGCCAGCAGACACATCCTGTCAGGTAGATACCTCCTGCCAGGGGGACCTGCC
CTTGCACCAGGAAGTGGACTCCTCAGATAGTGAGGTAGCTGTTACTCTCATCGATACTTCTCAACCCGGAGACCCACTGAGTCTACATGA
GCCCATAAAAATTGTTATCACGATGAGCAGTACCCCAAACTCCATGACAGATTTGGAAAGCTCCCTCCACCTGAGGGTGGTTGGCACAGA
GAAGACCAGTGTAAAGTCTGACGCTGAGCCCACTAACCCAGGGGCGGCCGGTTCTCCAAATGCCGAGCAGATCTCAATTCCTGTAATCAC
CCTGGACCTGCCTGAGGGTGGGGGAGGAGGTGTTCCCTGTCCCGAAGGCAATGGAAGTGAAAGGACTCCAGAGAGACTGAAGACGAGGGT
ATCCACCAATCAGTGTTCTGGCTACGGATCTGGGGAGGGGGGAAATGCCATCAAGGATCACAGTTCTTCATCACGGGAACCCTGGGAATC
GGTGTCCCGGCTTACACCTGATACAGGCTCCGAGTCTAAGGTGGGGAAGGAAGGCCAGACTAACCTTGACCCATCGTCTTGTAAGTCCAG
CCATGAAAAGAGGCATGCCCGGGTGCTCAGTGTGGACAGTGGGACAGATGTCTTCTTGAGTAAAAGTTCTGCAGAAATTGTTAACGATAC
AGAGAAAACAATGCCAACTTCCAAATCTGACCTAGAGGCTAAGGAAGGACAAATGCCAAATGAGTCCAACTTCCTGGAATTTGTCTCCCT
GTTAGAATCCATTAATACTTCCAAGATGACGGCATCCAGTCAACTGAATGGCTCAGCTGAGCAGAATGAAGAAAGTGGGCTTCTCCGAGA
TAACTGTTCCCAGGAAAAAAAGGAGGAAATCCTGGAAAATGAAAAGCCCAGTGGACACAGTTCTAAGCAAGGAAAACCAGATTTGCAAAG
TCAAGACCATACTAGCACCGGCCCCGCATGCACTCAGCCTGCCAAGACCACAGCCTTTTTTCAGGGCAATAGACAAAGACAGATAATCTA
CAGGGTAACTTCCCAACAAGATAGTTCTGTCTTGCAAGTCATCAGTGGGCCTGAAACATCTGTACAAGAAGAGATATCTGTGGATGCTAT
GCATGTCTTCATTGATGAACATGGGGAAATTAGATCCTGTTATTTAAAATCTGGAAATCAGAAAGAAGGCCCTTTACAGCCTCTACCATC
AAATAATGACTGTCTCTCTCAGGCTCGAGAGATGCAGGTCAGCTCCTCCAGTACCACAACTTCTGAGAGTCAAGATCCGTCTTCTGGGGA
CCCTGCCGTCAGTGCCCTTCAGCAACAGCTGTTACTGATGGTGGCTCGCAGGACCCAGTCGGAAACCCCACGGAGGCTGCAGTCAGTTCG
GGAAGGCTGTAGGACCCGCAGCCAGTGCAGGCACTCTGGACCTCTCAGGGTGGCGATGAAGTTTCCAGCGCGGAGTACCAGGGGAGCAAC
CAACAAAAAAGCAGAGTCCCGCCAGCCCTCAGAGAATTCTGTGACTGATTCCAACTCCGATTCAGAAGATGAAAGTGGAATGAATTTTTT
GGAGAAAAGGGCTTTAAATATAAAGCAAAACAAAGCAATGCTTGCAAAACTCATGTCTGAATTAGAAAGCTTCCCTGGCTCGTTCCGTGG
AAGACATCCCCTCCCAGGCTCCGACTCACAATCAAGGAGACCGCGAAGGCGTACATTCCCGGGTGTTGCTTCCAGGAGAAACCCTGAACG
GAGAGCTCGTCCTCTTACCAGGTCAAGGTCCCGGATCCTCGGGTCCCTTGACGCTCTACCCATGGAGGAGGAGGAGGAAGAGGATAAGTA
CATGTTGGTGAGAAAGAGGAAGACCGTGGATGGCTACATGAATGAAGATGACCTGCCCAGAAGCCGTCGCTCCAGATCATCCGTGACCCT
TCCGCATATAATTCGCCCAGTGGAAGAAATTACAGAGGAGGAGTTGGAGAACGTCTGCAGCAATTCTCGAGAGAAGATATATAACCGTTC
ACTGGGCTCTACTTGTCATCAATGCCGTCAGAAGACTATTGATACCAAAACAAACTGCAGAAACCCAGACTGCTGGGGCGTTCGAGGCCA
GTTCTGTGGCCCCTGCCTTCGAAACCGTTATGGTGAAGAGGTCAGGGATGCTCTGCTGGATCCGAACTGGCATTGCCCGCCTTGTCGAGG
AATCTGCAACTGCAGTTTCTGCCGGCAGCGAGATGGACGGTGTGCGACTGGGGTCCTTGTGTATTTAGCCAAATATCATGGCTTTGGGAA
TGTGCATGCCTACTTGAAAAGCCTGAAACAGGAATTTGAAATGCAAGCATAATATCTGGAAAATTTGCTGCCTGCCTTCTACTTCTCAAA
TCTTTCTTGTAAAAGTTTCCAATTTTTTCACTGAAACCTGAGTTAAAAATCTTGATGATCAGCCTGTTTCATAAGAAACTCCAATCAAGT
TAATCTTAGCAGACATGTGTTTCTGGAGCATCACAGAAGGTATATTGCTAGTTACACTTTGCCCTCCTGCAGTTTCTTCTCTGCTCCCAA
CCCCCATCTCACAGCATCCCCCTCTATTTCCAATGCTCCTCTCCAACCGCTTAGTTTCTGAATTTCTTTTAAATTACAGTTTTATGAAAG
CATATTTTATTTACTTGGTGTTGAAATAGCCCTCATAAAACCTAAGCACTTGGAAACACAATAATAGTATTAACTAACTAGATCTATTGA
ATTTCAGAGAAGAGCCTTCTAACTTGTTTACACAAAAACGAGTATGATTTAGCATTCATACTAGTTGAAATTTTTAATAGAATCAAGGCA
CAAAAGTCTTAAAACCATGTGGAAAAATTAGGTAATTATTGCAGATTGATGTCTCTCAATCCCATGTATTGCGCTTATGTTACAAGTTGT
TGTCACAGTTGAGACTTAATTTCTCCTAATTTCTTCTGCCCGAAGGGTAAGTGGTGCGTCCAGCTTACACAATCATAATTCAAAGGTTGG
TGGGCAATGTAATACTTAATTAAAATAATGATGGAAGAGCTATCTGGAGATTATGAGTAAGCTGATTTGAATTTTCAGTATAAAACTTTA
GTATAATTGTAGTTTGCAAAGTTTATTTCAGTTCACATGTAAGGTATTGCAAATAAATTCTTGGACAATTTTGTATGGAAACTTGATATT
AAAAACTAGTCTGTGGTTCTTTGCAGTTTCTTGTAAATTTATAAACCAGGCACAAGGTTCAAGTTTAGATTTTAAGCACTTTTATAACAA
TGATAAGTGCCTTTTTGGAGATGTAACTTTTAGCAGTTTGTTAACCTGACATCTCTGCCAGTCTAGTTTCTGGGCAGGTTTCCTGTGTCA
GTATTCCCCCTCCTCTTTGCATTAATCAAGGTATTTGGTAGAGGTGGAATCTAAGTGTTTGTATGTCCAATTTACTTGCATATGTAAACC
ATTGCTGTGCCATTCAATGTTTGATGCATAATTGGACCTTGAATCGATAAGTGTAAATACAGCTTTTGATCTGTAATGCTTTTATACAAA
AGTTTATTTTAATAATAAAATGTTTGTTCTAACTTGTCTGCTTTTTTAAAAATAATCTTACTGTACTTAATTCTAATTTTTTCCTCATAT

>63461_63461_1_PCNXL2-CDCA7_PCNXL2_chr1_233372591_ENST00000258229_CDCA7_chr2_174227954_ENST00000306721_length(amino acids)=1183AA_BP=861
MPGRSSRLRRRGSRVRAEEQLQLQTWGGRRRRGRRRRRRRGRGPRARVLDLREPGDPAGARRVQRGAHQPRGAAGMVSQVLQLLRQGVWA
ALTGGWYHDPEQSKFTNSCHLYLWLFLLLLPLALHLAFPPNAIIVFFYCSAVTIFFTIIKLVSYRLHLMFDKGEVIQQKPSRKEEKPNKD
KEAKGEHITNHRNPSNNRQIHNGKKEEASRNLSTPPLRCSSRGQSITSHHSSGPLELSAQETVEDLKGVILLEDHPIAPVSSTSPGIKVE
SLPASQAHMLETTTKSVIPVKPVATETLINGKGKERGGKGQPPLRHRSEGGLVDKGPLKKLPHLSLSQYDLLETDVSFQPWGSENSVLIP
EPVSCPRGSIRERVQSKSPQDSLSSSCPQCDTIVAKPVEEPADTSCQVDTSCQGDLPLHQEVDSSDSEVAVTLIDTSQPGDPLSLHEPIK
IVITMSSTPNSMTDLESSLHLRVVGTEKTSVKSDAEPTNPGAAGSPNAEQISIPVITLDLPEGGGGGVPCPEGNGSERTPERLKTRVSTN
QCSGYGSGEGGNAIKDHSSSSREPWESVSRLTPDTGSESKVGKEGQTNLDPSSCKSSHEKRHARVLSVDSGTDVFLSKSSAEIVNDTEKT
MPTSKSDLEAKEGQMPNESNFLEFVSLLESINTSKMTASSQLNGSAEQNEESGLLRDNCSQEKKEEILENEKPSGHSSKQGKPDLQSQDH
TSTGPACTQPAKTTAFFQGNRQRQIIYRVTSQQDSSVLQVISGPETSVQEEISVDAMHVFIDEHGEIRSCYLKSGNQKEGPLQPLPSNND
CLSQAREMQVSSSSTTTSESQDPSSGDPAVSALQQQLLLMVARRTQSETPRRLQSVREGCRTRSQCRHSGPLRVAMKFPARSTRGATNKK
AESRQPSENSVTDSNSDSEDESGMNFLEKRALNIKQNKAMLAKLMSELESFPGSFRGRHPLPGSDSQSRRPRRRTFPGVASRRNPERRAR
PLTRSRSRILGSLDALPMEEEEEEDKYMLVRKRKTVDGYMNEDDLPRSRRSRSSVTLPHIIRPVEEITEEELENVCSNSREKIYNRSLGS
TCHQCRQKTIDTKTNCRNPDCWGVRGQFCGPCLRNRYGEEVRDALLDPNWHCPPCRGICNCSFCRQRDGRCATGVLVYLAKYHGFGNVHA

--------------------------------------------------------------
>63461_63461_2_PCNXL2-CDCA7_PCNXL2_chr1_233372591_ENST00000258229_CDCA7_chr2_174227954_ENST00000347703_length(transcript)=4802nt_BP=2593nt
TGGCGCTCACCTGCCCGGCCGCAGCAGCCGGCTCCGGCGCCGCGGTTCGCGGGTCCGGGCGGAAGAGCAGCTCCAGCTTCAAACGTGGGG
TGGAAGGAGGCGGCGGGGGCGACGGCGGCGGCGACGGCGGGGGCGCGGCCCGCGGGCCCGGGTGTTAGACCTGAGGGAGCCTGGAGATCC
GGCCGGGGCGCGCAGGGTGCAGCGGGGCGCTCACCAGCCCCGGGGCGCAGCCGGCATGGTGTCCCAGGTGCTGCAGCTGCTCCGGCAGGG
CGTGTGGGCCGCGCTCACCGGGGGCTGGTACCACGACCCGGAGCAGAGCAAGTTCACCAACAGCTGCCACCTCTACCTGTGGCTGTTCCT
CCTGCTGCTGCCCCTGGCCCTGCACCTGGCTTTTCCTCCAAATGCGATCATTGTATTTTTCTACTGCAGTGCAGTGACTATATTCTTCAC
AATAATCAAACTGGTCAGTTATCGCCTACACCTCATGTTTGACAAAGGAGAAGTAATTCAGCAAAAGCCCTCCAGAAAGGAAGAAAAGCC
AAATAAAGACAAGGAGGCCAAAGGTGAACACATAACTAATCACAGAAATCCAAGCAATAATAGGCAGATTCACAATGGCAAAAAGGAAGA
GGCCAGTCGAAACCTCTCCACGCCTCCCCTCCGCTGCAGCTCCAGAGGGCAAAGCATAACCTCTCATCACTCTTCTGGGCCATTGGAGTT
GTCAGCACAGGAAACTGTAGAAGATCTCAAAGGTGTCATTCTATTAGAAGACCATCCCATAGCACCAGTGTCATCTACCTCACCTGGTAT
CAAAGTGGAAAGCTTACCTGCGTCTCAAGCACACATGCTGGAAACCACGACCAAGTCAGTAATACCTGTAAAACCAGTTGCCACAGAAAC
TCTCATCAATGGTAAAGGAAAGGAAAGAGGAGGCAAGGGGCAGCCTCCTTTGCGCCACAGATCCGAGGGTGGCTTAGTGGATAAGGGACC
CTTGAAGAAGTTGCCCCACCTGTCTTTGTCTCAGTATGACTTACTAGAAACAGACGTTTCTTTCCAGCCGTGGGGGAGTGAGAATTCAGT
CCTGATTCCAGAACCTGTCAGTTGTCCCCGGGGCTCCATAAGGGAACGGGTACAAAGCAAGTCACCTCAGGACAGCCTGAGCAGCAGCTG
CCCTCAATGTGACACCATCGTGGCCAAGCCTGTGGAGGAGCCAGCAGACACATCCTGTCAGGTAGATACCTCCTGCCAGGGGGACCTGCC
CTTGCACCAGGAAGTGGACTCCTCAGATAGTGAGGTAGCTGTTACTCTCATCGATACTTCTCAACCCGGAGACCCACTGAGTCTACATGA
GCCCATAAAAATTGTTATCACGATGAGCAGTACCCCAAACTCCATGACAGATTTGGAAAGCTCCCTCCACCTGAGGGTGGTTGGCACAGA
GAAGACCAGTGTAAAGTCTGACGCTGAGCCCACTAACCCAGGGGCGGCCGGTTCTCCAAATGCCGAGCAGATCTCAATTCCTGTAATCAC
CCTGGACCTGCCTGAGGGTGGGGGAGGAGGTGTTCCCTGTCCCGAAGGCAATGGAAGTGAAAGGACTCCAGAGAGACTGAAGACGAGGGT
ATCCACCAATCAGTGTTCTGGCTACGGATCTGGGGAGGGGGGAAATGCCATCAAGGATCACAGTTCTTCATCACGGGAACCCTGGGAATC
GGTGTCCCGGCTTACACCTGATACAGGCTCCGAGTCTAAGGTGGGGAAGGAAGGCCAGACTAACCTTGACCCATCGTCTTGTAAGTCCAG
CCATGAAAAGAGGCATGCCCGGGTGCTCAGTGTGGACAGTGGGACAGATGTCTTCTTGAGTAAAAGTTCTGCAGAAATTGTTAACGATAC
AGAGAAAACAATGCCAACTTCCAAATCTGACCTAGAGGCTAAGGAAGGACAAATGCCAAATGAGTCCAACTTCCTGGAATTTGTCTCCCT
GTTAGAATCCATTAATACTTCCAAGATGACGGCATCCAGTCAACTGAATGGCTCAGCTGAGCAGAATGAAGAAAGTGGGCTTCTCCGAGA
TAACTGTTCCCAGGAAAAAAAGGAGGAAATCCTGGAAAATGAAAAGCCCAGTGGACACAGTTCTAAGCAAGGAAAACCAGATTTGCAAAG
TCAAGACCATACTAGCACCGGCCCCGCATGCACTCAGCCTGCCAAGACCACAGCCTTTTTTCAGGGCAATAGACAAAGACAGATAATCTA
CAGGGTAACTTCCCAACAAGATAGTTCTGTCTTGCAAGTCATCAGTGGGCCTGAAACATCTGTACAAGAAGAGATATCTGTGGATGCTAT
GCATGTCTTCATTGATGAACATGGGGAAATTAGATCCTGTTATTTAAAATCTGGAAATCAGAAAGAAGGCCCTTTACAGCCTCTACCATC
AAATAATGACTGTCTCTCTCAGGCTCGAGAGATGCAGGTCAGCTCCTCCAGTACCACAACTTCTGAGAGTCAAGATCCGTCTTCTGGGGA
CCCTGCCGTCAGTGCCCTTCAGCAACAGCTGTTACTGATGGTGGCTCGCAGGACCCAGTCGGAAACCCCACGGAGGCTGCAGTCAGTTCG
GGAAGGCTGTAGGACCCGCAGCCAGTGCAGGCACTCTGGACCTCTCAGGGTGGCGATGAAGTTTCCAGCGCGGAGTACCAGGGGAGCAAC
CAACAAAAAAGCAGAGTCCCGCCAGCCCTCAGAGAATTCTGTGACTGATTCCAACTCCGATTCAGAAGATGAAAGTGGAATGAATTTTTT
GGAGAAAAGGGCTTTAAATATAAAGCAAAACAAAGCAATGCTTGCAAAACTCATGTCTGAATTAGAAAGCTTCCCTGGCTCGTTCCGTGG
AAGACATCCCCTCCCAGGCTCCGACTCACAATCAAGGAGACCGCGAAGGCGTACATTCCCGGGTGTTGCTTCCAGGAGAAACCCTGAACG
GAGAGCTCGTCCTCTTACCAGGTCAAGGTCCCGGATCCTCGGGTCCCTTGACGCTCTACCCATGGAGGAGGAGGAGGAAGAGGATAAGTA
CATGTTGGTGAGAAAGAGGAAGACCGTGGATGGCTACATGAATGAAGATGACCTGCCCAGAAGCCGTCGCTCCAGATCATCCGTGACCCT
TCCGCATATAATTCGCCCAGTGGAAGAAATTACAGAGGAGGAGTTGGAGAACGTCTGCAGCAATTCTCGAGAGAAGATATATAACCGTTC
ACTGGGCTCTACTTGTCATCAATGCCGTCAGAAGACTATTGATACCAAAACAAACTGCAGAAACCCAGACTGCTGGGGCGTTCGAGGCCA
GTTCTGTGGCCCCTGCCTTCGAAACCGTTATGGTGAAGAGGTCAGGGATGCTCTGCTGGATCCGAACTGGCATTGCCCGCCTTGTCGAGG
AATCTGCAACTGCAGTTTCTGCCGGCAGCGAGATGGACGGTGTGCGACTGGGGTCCTTGTGTATTTAGCCAAATATCATGGCTTTGGGAA
TGTGCATGCCTACTTGAAAAGCCTGAAACAGGAATTTGAAATGCAAGCATAATATCTGGAAAATTTGCTGCCTGCCTTCTACTTCTCAAA
TCTTTCTTGTAAAAGTTTCCAATTTTTTCACTGAAACCTGAGTTAAAAATCTTGATGATCAGCCTGTTTCATAAGAAACTCCAATCAAGT
TAATCTTAGCAGACATGTGTTTCTGGAGCATCACAGAAGGTATATTGCTAGTTACACTTTGCCCTCCTGCAGTTTCTTCTCTGCTCCCAA
CCCCCATCTCACAGCATCCCCCTCTATTTCCAATGCTCCTCTCCAACCGCTTAGTTTCTGAATTTCTTTTAAATTACAGTTTTATGAAAG
CATATTTTATTTACTTGGTGTTGAAATAGCCCTCATAAAACCTAAGCACTTGGAAACACAATAATAGTATTAACTAACTAGATCTATTGA
ATTTCAGAGAAGAGCCTTCTAACTTGTTTACACAAAAACGAGTATGATTTAGCATTCATACTAGTTGAAATTTTTAATAGAATCAAGGCA
CAAAAGTCTTAAAACCATGTGGAAAAATTAGGTAATTATTGCAGATTGATGTCTCTCAATCCCATGTATTGCGCTTATGTTACAAGTTGT
TGTCACAGTTGAGACTTAATTTCTCCTAATTTCTTCTGCCCGAAGGGTAAGTGGTGCGTCCAGCTTACACAATCATAATTCAAAGGTTGG
TGGGCAATGTAATACTTAATTAAAATAATGATGGAAGAGCTATCTGGAGATTATGAGTAAGCTGATTTGAATTTTCAGTATAAAACTTTA
GTATAATTGTAGTTTGCAAAGTTTATTTCAGTTCACATGTAAGGTATTGCAAATAAATTCTTGGACAATTTTGTATGGAAACTTGATATT
AAAAACTAGTCTGTGGTTCTTTGCAGTTTCTTGTAAATTTATAAACCAGGCACAAGGTTCAAGTTTAGATTTTAAGCACTTTTATAACAA
TGATAAGTGCCTTTTTGGAGATGTAACTTTTAGCAGTTTGTTAACCTGACATCTCTGCCAGTCTAGTTTCTGGGCAGGTTTCCTGTGTCA
GTATTCCCCCTCCTCTTTGCATTAATCAAGGTATTTGGTAGAGGTGGAATCTAAGTGTTTGTATGTCCAATTTACTTGCATATGTAAACC
ATTGCTGTGCCATTCAATGTTTGATGCATAATTGGACCTTGAATCGATAAGTGTAAATACAGCTTTTGATCTGTAATGCTTTTATACAAA

>63461_63461_2_PCNXL2-CDCA7_PCNXL2_chr1_233372591_ENST00000258229_CDCA7_chr2_174227954_ENST00000347703_length(amino acids)=1183AA_BP=861
MPGRSSRLRRRGSRVRAEEQLQLQTWGGRRRRGRRRRRRRGRGPRARVLDLREPGDPAGARRVQRGAHQPRGAAGMVSQVLQLLRQGVWA
ALTGGWYHDPEQSKFTNSCHLYLWLFLLLLPLALHLAFPPNAIIVFFYCSAVTIFFTIIKLVSYRLHLMFDKGEVIQQKPSRKEEKPNKD
KEAKGEHITNHRNPSNNRQIHNGKKEEASRNLSTPPLRCSSRGQSITSHHSSGPLELSAQETVEDLKGVILLEDHPIAPVSSTSPGIKVE
SLPASQAHMLETTTKSVIPVKPVATETLINGKGKERGGKGQPPLRHRSEGGLVDKGPLKKLPHLSLSQYDLLETDVSFQPWGSENSVLIP
EPVSCPRGSIRERVQSKSPQDSLSSSCPQCDTIVAKPVEEPADTSCQVDTSCQGDLPLHQEVDSSDSEVAVTLIDTSQPGDPLSLHEPIK
IVITMSSTPNSMTDLESSLHLRVVGTEKTSVKSDAEPTNPGAAGSPNAEQISIPVITLDLPEGGGGGVPCPEGNGSERTPERLKTRVSTN
QCSGYGSGEGGNAIKDHSSSSREPWESVSRLTPDTGSESKVGKEGQTNLDPSSCKSSHEKRHARVLSVDSGTDVFLSKSSAEIVNDTEKT
MPTSKSDLEAKEGQMPNESNFLEFVSLLESINTSKMTASSQLNGSAEQNEESGLLRDNCSQEKKEEILENEKPSGHSSKQGKPDLQSQDH
TSTGPACTQPAKTTAFFQGNRQRQIIYRVTSQQDSSVLQVISGPETSVQEEISVDAMHVFIDEHGEIRSCYLKSGNQKEGPLQPLPSNND
CLSQAREMQVSSSSTTTSESQDPSSGDPAVSALQQQLLLMVARRTQSETPRRLQSVREGCRTRSQCRHSGPLRVAMKFPARSTRGATNKK
AESRQPSENSVTDSNSDSEDESGMNFLEKRALNIKQNKAMLAKLMSELESFPGSFRGRHPLPGSDSQSRRPRRRTFPGVASRRNPERRAR
PLTRSRSRILGSLDALPMEEEEEEDKYMLVRKRKTVDGYMNEDDLPRSRRSRSSVTLPHIIRPVEEITEEELENVCSNSREKIYNRSLGS
TCHQCRQKTIDTKTNCRNPDCWGVRGQFCGPCLRNRYGEEVRDALLDPNWHCPPCRGICNCSFCRQRDGRCATGVLVYLAKYHGFGNVHA

--------------------------------------------------------------
>63461_63461_3_PCNXL2-CDCA7_PCNXL2_chr1_233372591_ENST00000258229_CDCA7_chr2_174227954_ENST00000392567_length(transcript)=4739nt_BP=2593nt
TGGCGCTCACCTGCCCGGCCGCAGCAGCCGGCTCCGGCGCCGCGGTTCGCGGGTCCGGGCGGAAGAGCAGCTCCAGCTTCAAACGTGGGG
TGGAAGGAGGCGGCGGGGGCGACGGCGGCGGCGACGGCGGGGGCGCGGCCCGCGGGCCCGGGTGTTAGACCTGAGGGAGCCTGGAGATCC
GGCCGGGGCGCGCAGGGTGCAGCGGGGCGCTCACCAGCCCCGGGGCGCAGCCGGCATGGTGTCCCAGGTGCTGCAGCTGCTCCGGCAGGG
CGTGTGGGCCGCGCTCACCGGGGGCTGGTACCACGACCCGGAGCAGAGCAAGTTCACCAACAGCTGCCACCTCTACCTGTGGCTGTTCCT
CCTGCTGCTGCCCCTGGCCCTGCACCTGGCTTTTCCTCCAAATGCGATCATTGTATTTTTCTACTGCAGTGCAGTGACTATATTCTTCAC
AATAATCAAACTGGTCAGTTATCGCCTACACCTCATGTTTGACAAAGGAGAAGTAATTCAGCAAAAGCCCTCCAGAAAGGAAGAAAAGCC
AAATAAAGACAAGGAGGCCAAAGGTGAACACATAACTAATCACAGAAATCCAAGCAATAATAGGCAGATTCACAATGGCAAAAAGGAAGA
GGCCAGTCGAAACCTCTCCACGCCTCCCCTCCGCTGCAGCTCCAGAGGGCAAAGCATAACCTCTCATCACTCTTCTGGGCCATTGGAGTT
GTCAGCACAGGAAACTGTAGAAGATCTCAAAGGTGTCATTCTATTAGAAGACCATCCCATAGCACCAGTGTCATCTACCTCACCTGGTAT
CAAAGTGGAAAGCTTACCTGCGTCTCAAGCACACATGCTGGAAACCACGACCAAGTCAGTAATACCTGTAAAACCAGTTGCCACAGAAAC
TCTCATCAATGGTAAAGGAAAGGAAAGAGGAGGCAAGGGGCAGCCTCCTTTGCGCCACAGATCCGAGGGTGGCTTAGTGGATAAGGGACC
CTTGAAGAAGTTGCCCCACCTGTCTTTGTCTCAGTATGACTTACTAGAAACAGACGTTTCTTTCCAGCCGTGGGGGAGTGAGAATTCAGT
CCTGATTCCAGAACCTGTCAGTTGTCCCCGGGGCTCCATAAGGGAACGGGTACAAAGCAAGTCACCTCAGGACAGCCTGAGCAGCAGCTG
CCCTCAATGTGACACCATCGTGGCCAAGCCTGTGGAGGAGCCAGCAGACACATCCTGTCAGGTAGATACCTCCTGCCAGGGGGACCTGCC
CTTGCACCAGGAAGTGGACTCCTCAGATAGTGAGGTAGCTGTTACTCTCATCGATACTTCTCAACCCGGAGACCCACTGAGTCTACATGA
GCCCATAAAAATTGTTATCACGATGAGCAGTACCCCAAACTCCATGACAGATTTGGAAAGCTCCCTCCACCTGAGGGTGGTTGGCACAGA
GAAGACCAGTGTAAAGTCTGACGCTGAGCCCACTAACCCAGGGGCGGCCGGTTCTCCAAATGCCGAGCAGATCTCAATTCCTGTAATCAC
CCTGGACCTGCCTGAGGGTGGGGGAGGAGGTGTTCCCTGTCCCGAAGGCAATGGAAGTGAAAGGACTCCAGAGAGACTGAAGACGAGGGT
ATCCACCAATCAGTGTTCTGGCTACGGATCTGGGGAGGGGGGAAATGCCATCAAGGATCACAGTTCTTCATCACGGGAACCCTGGGAATC
GGTGTCCCGGCTTACACCTGATACAGGCTCCGAGTCTAAGGTGGGGAAGGAAGGCCAGACTAACCTTGACCCATCGTCTTGTAAGTCCAG
CCATGAAAAGAGGCATGCCCGGGTGCTCAGTGTGGACAGTGGGACAGATGTCTTCTTGAGTAAAAGTTCTGCAGAAATTGTTAACGATAC
AGAGAAAACAATGCCAACTTCCAAATCTGACCTAGAGGCTAAGGAAGGACAAATGCCAAATGAGTCCAACTTCCTGGAATTTGTCTCCCT
GTTAGAATCCATTAATACTTCCAAGATGACGGCATCCAGTCAACTGAATGGCTCAGCTGAGCAGAATGAAGAAAGTGGGCTTCTCCGAGA
TAACTGTTCCCAGGAAAAAAAGGAGGAAATCCTGGAAAATGAAAAGCCCAGTGGACACAGTTCTAAGCAAGGAAAACCAGATTTGCAAAG
TCAAGACCATACTAGCACCGGCCCCGCATGCACTCAGCCTGCCAAGACCACAGCCTTTTTTCAGGGCAATAGACAAAGACAGATAATCTA
CAGGGTAACTTCCCAACAAGATAGTTCTGTCTTGCAAGTCATCAGTGGGCCTGAAACATCTGTACAAGAAGAGATATCTGTGGATGCTAT
GCATGTCTTCATTGATGAACATGGGGAAATTAGATCCTGTTATTTAAAATCTGGAAATCAGAAAGAAGGCCCTTTACAGCCTCTACCATC
AAATAATGACTGTCTCTCTCAGGCTCGAGAGATGCAGGTCAGCTCCTCCAGTACCACAACTTCTGAGAGTCAAGATCCGTCTTCTGGGGA
CCCTGCCGTCAGTGCCCTTCAGCAACAGCTGTTACTGATGGTGGCTCGCAGGACCCAGTCGGAAACCCCACGGAGGCTGCAGTCAGTTCG
GGAAGGCTGTAGGACCCGCAGCCAGTGCAGGCACTCTGGACCTCTCAGGGTGGCGATGAAGTTTCCAGCGCGGAGTACCAGGGGAGCAAC
CAACAAAAAAGCAGAGTCCCGCCAGCCCTCAGAGAATTCTGTGACTGATTCCAACTCCGATTCAGAAGATGAAAGTGGAATGAATTTTTT
GGAGAAAAGGGCTTTAAATATAAAGCAAAACAAAGCAATGCTTGCAAAACTCATGTCTGAATTAGAAAGCTTCCCTGGCTCGTTCCGTGG
AAGACATCCCCTCCCAGGCTCCGACTCACAATCAAGGAGACCGCGAAGGCGTACATTCCCGGGTGTTGCTTCCAGGAGAAACCCTGAACG
GAGAGCTCGTCCTCTTACCAGGTCAAGGTCCCGGATCCTCGGGTCCCTTGACGCTCTACCCATGGAGGAGGAGGAGGAAGAGGATAAGTA
CATGTTGGTGAGAAAGAGGAAGACCGTGGATGGCTACATGAATGAAGATGACCTGCCCAGAAGCCGTCGCTCCAGATCATCCGTGACCCT
TCCGCATATAATTCGCCCAGTGGAAGAAATTACAGAGGAGGAGTTGGAGAACGTCTGCAGCAATTCTCGAGAGAAGATATATAACCGTTC
ACTGAACTGGCATTGCCCGCCTTGTCGAGGAATCTGCAACTGCAGTTTCTGCCGGCAGCGAGATGGACGGTGTGCGACTGGGGTCCTTGT
GTATTTAGCCAAATATCATGGCTTTGGGAATGTGCATGCCTACTTGAAAAGCCTGAAACAGGAATTTGAAATGCAAGCATAATATCTGGA
AAATTTGCTGCCTGCCTTCTACTTCTCAAATCTTTCTTGTAAAAGTTTCCAATTTTTTCACTGAAACCTGAGTTAAAAATCTTGATGATC
AGCCTGTTTCATAAGAAACTCCAATCAAGTTAATCTTAGCAGACATGTGTTTCTGGAGCATCACAGAAGGTATATTGCTAGTTACACTTT
GCCCTCCTGCAGTTTCTTCTCTGCTCCCAACCCCCATCTCACAGCATCCCCCTCTATTTCCAATGCTCCTCTCCAACCGCTTAGTTTCTG
AATTTCTTTTAAATTACAGTTTTATGAAAGCATATTTTATTTACTTGGTGTTGAAATAGCCCTCATAAAACCTAAGCACTTGGAAACACA
ATAATAGTATTAACTAACTAGATCTATTGAATTTCAGAGAAGAGCCTTCTAACTTGTTTACACAAAAACGAGTATGATTTAGCATTCATA
CTAGTTGAAATTTTTAATAGAATCAAGGCACAAAAGTCTTAAAACCATGTGGAAAAATTAGGTAATTATTGCAGATTGATGTCTCTCAAT
CCCATGTATTGCGCTTATGTTACAAGTTGTTGTCACAGTTGAGACTTAATTTCTCCTAATTTCTTCTGCCCGAAGGGTAAGTGGTGCGTC
CAGCTTACACAATCATAATTCAAAGGTTGGTGGGCAATGTAATACTTAATTAAAATAATGATGGAAGAGCTATCTGGAGATTATGAGTAA
GCTGATTTGAATTTTCAGTATAAAACTTTAGTATAATTGTAGTTTGCAAAGTTTATTTCAGTTCACATGTAAGGTATTGCAAATAAATTC
TTGGACAATTTTGTATGGAAACTTGATATTAAAAACTAGTCTGTGGTTCTTTGCAGTTTCTTGTAAATTTATAAACCAGGCACAAGGTTC
AAGTTTAGATTTTAAGCACTTTTATAACAATGATAAGTGCCTTTTTGGAGATGTAACTTTTAGCAGTTTGTTAACCTGACATCTCTGCCA
GTCTAGTTTCTGGGCAGGTTTCCTGTGTCAGTATTCCCCCTCCTCTTTGCATTAATCAAGGTATTTGGTAGAGGTGGAATCTAAGTGTTT
GTATGTCCAATTTACTTGCATATGTAAACCATTGCTGTGCCATTCAATGTTTGATGCATAATTGGACCTTGAATCGATAAGTGTAAATAC
AGCTTTTGATCTGTAATGCTTTTATACAAAAGTTTATTTTAATAATAAAATGTTTGTTCTAACTTGTCTGCTTTTTTAAAAATAATCTTA

>63461_63461_3_PCNXL2-CDCA7_PCNXL2_chr1_233372591_ENST00000258229_CDCA7_chr2_174227954_ENST00000392567_length(amino acids)=1133AA_BP=861
MPGRSSRLRRRGSRVRAEEQLQLQTWGGRRRRGRRRRRRRGRGPRARVLDLREPGDPAGARRVQRGAHQPRGAAGMVSQVLQLLRQGVWA
ALTGGWYHDPEQSKFTNSCHLYLWLFLLLLPLALHLAFPPNAIIVFFYCSAVTIFFTIIKLVSYRLHLMFDKGEVIQQKPSRKEEKPNKD
KEAKGEHITNHRNPSNNRQIHNGKKEEASRNLSTPPLRCSSRGQSITSHHSSGPLELSAQETVEDLKGVILLEDHPIAPVSSTSPGIKVE
SLPASQAHMLETTTKSVIPVKPVATETLINGKGKERGGKGQPPLRHRSEGGLVDKGPLKKLPHLSLSQYDLLETDVSFQPWGSENSVLIP
EPVSCPRGSIRERVQSKSPQDSLSSSCPQCDTIVAKPVEEPADTSCQVDTSCQGDLPLHQEVDSSDSEVAVTLIDTSQPGDPLSLHEPIK
IVITMSSTPNSMTDLESSLHLRVVGTEKTSVKSDAEPTNPGAAGSPNAEQISIPVITLDLPEGGGGGVPCPEGNGSERTPERLKTRVSTN
QCSGYGSGEGGNAIKDHSSSSREPWESVSRLTPDTGSESKVGKEGQTNLDPSSCKSSHEKRHARVLSVDSGTDVFLSKSSAEIVNDTEKT
MPTSKSDLEAKEGQMPNESNFLEFVSLLESINTSKMTASSQLNGSAEQNEESGLLRDNCSQEKKEEILENEKPSGHSSKQGKPDLQSQDH
TSTGPACTQPAKTTAFFQGNRQRQIIYRVTSQQDSSVLQVISGPETSVQEEISVDAMHVFIDEHGEIRSCYLKSGNQKEGPLQPLPSNND
CLSQAREMQVSSSSTTTSESQDPSSGDPAVSALQQQLLLMVARRTQSETPRRLQSVREGCRTRSQCRHSGPLRVAMKFPARSTRGATNKK
AESRQPSENSVTDSNSDSEDESGMNFLEKRALNIKQNKAMLAKLMSELESFPGSFRGRHPLPGSDSQSRRPRRRTFPGVASRRNPERRAR
PLTRSRSRILGSLDALPMEEEEEEDKYMLVRKRKTVDGYMNEDDLPRSRRSRSSVTLPHIIRPVEEITEEELENVCSNSREKIYNRSLNW

--------------------------------------------------------------
>63461_63461_4_PCNXL2-CDCA7_PCNXL2_chr1_233372591_ENST00000258229_CDCA7_chr2_174227954_ENST00000410019_length(transcript)=3968nt_BP=2593nt
TGGCGCTCACCTGCCCGGCCGCAGCAGCCGGCTCCGGCGCCGCGGTTCGCGGGTCCGGGCGGAAGAGCAGCTCCAGCTTCAAACGTGGGG
TGGAAGGAGGCGGCGGGGGCGACGGCGGCGGCGACGGCGGGGGCGCGGCCCGCGGGCCCGGGTGTTAGACCTGAGGGAGCCTGGAGATCC
GGCCGGGGCGCGCAGGGTGCAGCGGGGCGCTCACCAGCCCCGGGGCGCAGCCGGCATGGTGTCCCAGGTGCTGCAGCTGCTCCGGCAGGG
CGTGTGGGCCGCGCTCACCGGGGGCTGGTACCACGACCCGGAGCAGAGCAAGTTCACCAACAGCTGCCACCTCTACCTGTGGCTGTTCCT
CCTGCTGCTGCCCCTGGCCCTGCACCTGGCTTTTCCTCCAAATGCGATCATTGTATTTTTCTACTGCAGTGCAGTGACTATATTCTTCAC
AATAATCAAACTGGTCAGTTATCGCCTACACCTCATGTTTGACAAAGGAGAAGTAATTCAGCAAAAGCCCTCCAGAAAGGAAGAAAAGCC
AAATAAAGACAAGGAGGCCAAAGGTGAACACATAACTAATCACAGAAATCCAAGCAATAATAGGCAGATTCACAATGGCAAAAAGGAAGA
GGCCAGTCGAAACCTCTCCACGCCTCCCCTCCGCTGCAGCTCCAGAGGGCAAAGCATAACCTCTCATCACTCTTCTGGGCCATTGGAGTT
GTCAGCACAGGAAACTGTAGAAGATCTCAAAGGTGTCATTCTATTAGAAGACCATCCCATAGCACCAGTGTCATCTACCTCACCTGGTAT
CAAAGTGGAAAGCTTACCTGCGTCTCAAGCACACATGCTGGAAACCACGACCAAGTCAGTAATACCTGTAAAACCAGTTGCCACAGAAAC
TCTCATCAATGGTAAAGGAAAGGAAAGAGGAGGCAAGGGGCAGCCTCCTTTGCGCCACAGATCCGAGGGTGGCTTAGTGGATAAGGGACC
CTTGAAGAAGTTGCCCCACCTGTCTTTGTCTCAGTATGACTTACTAGAAACAGACGTTTCTTTCCAGCCGTGGGGGAGTGAGAATTCAGT
CCTGATTCCAGAACCTGTCAGTTGTCCCCGGGGCTCCATAAGGGAACGGGTACAAAGCAAGTCACCTCAGGACAGCCTGAGCAGCAGCTG
CCCTCAATGTGACACCATCGTGGCCAAGCCTGTGGAGGAGCCAGCAGACACATCCTGTCAGGTAGATACCTCCTGCCAGGGGGACCTGCC
CTTGCACCAGGAAGTGGACTCCTCAGATAGTGAGGTAGCTGTTACTCTCATCGATACTTCTCAACCCGGAGACCCACTGAGTCTACATGA
GCCCATAAAAATTGTTATCACGATGAGCAGTACCCCAAACTCCATGACAGATTTGGAAAGCTCCCTCCACCTGAGGGTGGTTGGCACAGA
GAAGACCAGTGTAAAGTCTGACGCTGAGCCCACTAACCCAGGGGCGGCCGGTTCTCCAAATGCCGAGCAGATCTCAATTCCTGTAATCAC
CCTGGACCTGCCTGAGGGTGGGGGAGGAGGTGTTCCCTGTCCCGAAGGCAATGGAAGTGAAAGGACTCCAGAGAGACTGAAGACGAGGGT
ATCCACCAATCAGTGTTCTGGCTACGGATCTGGGGAGGGGGGAAATGCCATCAAGGATCACAGTTCTTCATCACGGGAACCCTGGGAATC
GGTGTCCCGGCTTACACCTGATACAGGCTCCGAGTCTAAGGTGGGGAAGGAAGGCCAGACTAACCTTGACCCATCGTCTTGTAAGTCCAG
CCATGAAAAGAGGCATGCCCGGGTGCTCAGTGTGGACAGTGGGACAGATGTCTTCTTGAGTAAAAGTTCTGCAGAAATTGTTAACGATAC
AGAGAAAACAATGCCAACTTCCAAATCTGACCTAGAGGCTAAGGAAGGACAAATGCCAAATGAGTCCAACTTCCTGGAATTTGTCTCCCT
GTTAGAATCCATTAATACTTCCAAGATGACGGCATCCAGTCAACTGAATGGCTCAGCTGAGCAGAATGAAGAAAGTGGGCTTCTCCGAGA
TAACTGTTCCCAGGAAAAAAAGGAGGAAATCCTGGAAAATGAAAAGCCCAGTGGACACAGTTCTAAGCAAGGAAAACCAGATTTGCAAAG
TCAAGACCATACTAGCACCGGCCCCGCATGCACTCAGCCTGCCAAGACCACAGCCTTTTTTCAGGGCAATAGACAAAGACAGATAATCTA
CAGGGTAACTTCCCAACAAGATAGTTCTGTCTTGCAAGTCATCAGTGGGCCTGAAACATCTGTACAAGAAGAGATATCTGTGGATGCTAT
GCATGTCTTCATTGATGAACATGGGGAAATTAGATCCTGTTATTTAAAATCTGGAAATCAGAAAGAAGGCCCTTTACAGCCTCTACCATC
AAATAATGACTGTCTCTCTCAGGCTCGAGAGATGCAGGTCAGCTCCTCCAGTACCACAACTTCTGAGAGTCAAGATCCGTCTTCTGGGGA
CCCTGCCGTCAGTGCCCTTCAGCAACAGCTGTTACTGATGGTGGCTCGCAGGACCCAGTCGGAAACCCCACGGAGGCTGCAGTCAGTTCG
GGAAGGCTGTAGGACCCGCAGCCAGTGCAGGCACTCTGGACCTCTCAGGGTGGCGATGAAGTTTCCAGCGCGGAGTACCAGGGGAGCAAC
CAACAAAAAAGCAGAGTCCCGCCAGCCCTCAGAGAATTCTGTGACTGATTCCAACTCCGATTCAGAAGATGAAAGTGGAATGAATTTTTT
GGAGAAAAGGGCTTTAAATATAAAGCAAAACAAAGCAATGCTTGCAAAACTCATGTCTGAATTAGAAAGCTTCCCTGGCTCGTTCCGTGG
AAGACATCCCCTCCCAGGCTCCGACTCACAATCAAGGAGACCGCGAAGGCGTACATTCCCGGGTGTTGCTTCCAGGAGAAACCCTGAACG
GAGAGCTCGTCCTCTTACCAGGTCAAGGTCCCGGATCCTCGGGTCCCTTGACGCTCTACCCATGGAGGAGGAGGAGGAAGAGGATAAGTA
CATGTTGGTGAGAAAGAGGAAGACCGTGGATGGCTACATGAATGAAGATGACCTGCCCAGAAGCCGTCGCTCCAGATCATCCGTGACCCT
TCCGCATATAATTCGCCCAGTGGAAGAAATTACAGAGGAGGAGTTGGAGAACGTCTGCAGCAATTCTCGAGAGAAGATATATAACCGTTC
ACTGGGCTCTACTTGTCATCAATGCCGTCAGAAGACTATTGATACCAAAACAAACTGCAGAAACCCAGACTGCTGGGGCGTTCGAGGCCA
GTTCTGTGGCCCCTGCCTTCGAAACCGTTATGGTGAAGAGGTCAGGGATGCTCTGCTGGATCCGAACTGGCATTGCCCGCCTTGTCGAGG
AATCTGCAACTGCAGTTTCTGCCGGCAGCGAGATGGACGGTGTGCGACTGGGGTCCTTGTGTATTTAGCCAAATATCATGGCTTTGGGAA
TGTGCATGCCTACTTGAAAAGCCTGAAACAGGAATTTGAAATGCAAGCATAATATCTGGAAAATTTGCTGCCTGCCTTCTACTTCTCAAA
TCTTTCTTGTAAAAGTTTCCAATTTTTTCACTGAAACCTGAGTTAAAAATCTTGATGATCAGCCTGTTTCATAAGAAACTCCAATCAAGT
TAATCTTAGCAGACATGTGTTTCTGGAGCATCACAGAAGGTATATTGCTAGTTACACTTTGCCCTCCTGCAGTTTCTTCTCTGCTCCCAA
CCCCCATCTCACAGCATCCCCCTCTATTTCCAATGCTCCTCTCCAACCGCTTAGTTTCTGAATTTCTTTTAAATTACAGTTTTATGAAAG
CATATTTTATTTACTTGGTGTTGAAATAGCCCTCATAAAACCTAAGCACTTGGAAACACAATAATAGTATTAACTAACTAGATCTATTGA

>63461_63461_4_PCNXL2-CDCA7_PCNXL2_chr1_233372591_ENST00000258229_CDCA7_chr2_174227954_ENST00000410019_length(amino acids)=1183AA_BP=861
MPGRSSRLRRRGSRVRAEEQLQLQTWGGRRRRGRRRRRRRGRGPRARVLDLREPGDPAGARRVQRGAHQPRGAAGMVSQVLQLLRQGVWA
ALTGGWYHDPEQSKFTNSCHLYLWLFLLLLPLALHLAFPPNAIIVFFYCSAVTIFFTIIKLVSYRLHLMFDKGEVIQQKPSRKEEKPNKD
KEAKGEHITNHRNPSNNRQIHNGKKEEASRNLSTPPLRCSSRGQSITSHHSSGPLELSAQETVEDLKGVILLEDHPIAPVSSTSPGIKVE
SLPASQAHMLETTTKSVIPVKPVATETLINGKGKERGGKGQPPLRHRSEGGLVDKGPLKKLPHLSLSQYDLLETDVSFQPWGSENSVLIP
EPVSCPRGSIRERVQSKSPQDSLSSSCPQCDTIVAKPVEEPADTSCQVDTSCQGDLPLHQEVDSSDSEVAVTLIDTSQPGDPLSLHEPIK
IVITMSSTPNSMTDLESSLHLRVVGTEKTSVKSDAEPTNPGAAGSPNAEQISIPVITLDLPEGGGGGVPCPEGNGSERTPERLKTRVSTN
QCSGYGSGEGGNAIKDHSSSSREPWESVSRLTPDTGSESKVGKEGQTNLDPSSCKSSHEKRHARVLSVDSGTDVFLSKSSAEIVNDTEKT
MPTSKSDLEAKEGQMPNESNFLEFVSLLESINTSKMTASSQLNGSAEQNEESGLLRDNCSQEKKEEILENEKPSGHSSKQGKPDLQSQDH
TSTGPACTQPAKTTAFFQGNRQRQIIYRVTSQQDSSVLQVISGPETSVQEEISVDAMHVFIDEHGEIRSCYLKSGNQKEGPLQPLPSNND
CLSQAREMQVSSSSTTTSESQDPSSGDPAVSALQQQLLLMVARRTQSETPRRLQSVREGCRTRSQCRHSGPLRVAMKFPARSTRGATNKK
AESRQPSENSVTDSNSDSEDESGMNFLEKRALNIKQNKAMLAKLMSELESFPGSFRGRHPLPGSDSQSRRPRRRTFPGVASRRNPERRAR
PLTRSRSRILGSLDALPMEEEEEEDKYMLVRKRKTVDGYMNEDDLPRSRRSRSSVTLPHIIRPVEEITEEELENVCSNSREKIYNRSLGS
TCHQCRQKTIDTKTNCRNPDCWGVRGQFCGPCLRNRYGEEVRDALLDPNWHCPPCRGICNCSFCRQRDGRCATGVLVYLAKYHGFGNVHA

--------------------------------------------------------------
>63461_63461_5_PCNXL2-CDCA7_PCNXL2_chr1_233372591_ENST00000258229_CDCA7_chr2_174227954_ENST00000410101_length(transcript)=3618nt_BP=2593nt
TGGCGCTCACCTGCCCGGCCGCAGCAGCCGGCTCCGGCGCCGCGGTTCGCGGGTCCGGGCGGAAGAGCAGCTCCAGCTTCAAACGTGGGG
TGGAAGGAGGCGGCGGGGGCGACGGCGGCGGCGACGGCGGGGGCGCGGCCCGCGGGCCCGGGTGTTAGACCTGAGGGAGCCTGGAGATCC
GGCCGGGGCGCGCAGGGTGCAGCGGGGCGCTCACCAGCCCCGGGGCGCAGCCGGCATGGTGTCCCAGGTGCTGCAGCTGCTCCGGCAGGG
CGTGTGGGCCGCGCTCACCGGGGGCTGGTACCACGACCCGGAGCAGAGCAAGTTCACCAACAGCTGCCACCTCTACCTGTGGCTGTTCCT
CCTGCTGCTGCCCCTGGCCCTGCACCTGGCTTTTCCTCCAAATGCGATCATTGTATTTTTCTACTGCAGTGCAGTGACTATATTCTTCAC
AATAATCAAACTGGTCAGTTATCGCCTACACCTCATGTTTGACAAAGGAGAAGTAATTCAGCAAAAGCCCTCCAGAAAGGAAGAAAAGCC
AAATAAAGACAAGGAGGCCAAAGGTGAACACATAACTAATCACAGAAATCCAAGCAATAATAGGCAGATTCACAATGGCAAAAAGGAAGA
GGCCAGTCGAAACCTCTCCACGCCTCCCCTCCGCTGCAGCTCCAGAGGGCAAAGCATAACCTCTCATCACTCTTCTGGGCCATTGGAGTT
GTCAGCACAGGAAACTGTAGAAGATCTCAAAGGTGTCATTCTATTAGAAGACCATCCCATAGCACCAGTGTCATCTACCTCACCTGGTAT
CAAAGTGGAAAGCTTACCTGCGTCTCAAGCACACATGCTGGAAACCACGACCAAGTCAGTAATACCTGTAAAACCAGTTGCCACAGAAAC
TCTCATCAATGGTAAAGGAAAGGAAAGAGGAGGCAAGGGGCAGCCTCCTTTGCGCCACAGATCCGAGGGTGGCTTAGTGGATAAGGGACC
CTTGAAGAAGTTGCCCCACCTGTCTTTGTCTCAGTATGACTTACTAGAAACAGACGTTTCTTTCCAGCCGTGGGGGAGTGAGAATTCAGT
CCTGATTCCAGAACCTGTCAGTTGTCCCCGGGGCTCCATAAGGGAACGGGTACAAAGCAAGTCACCTCAGGACAGCCTGAGCAGCAGCTG
CCCTCAATGTGACACCATCGTGGCCAAGCCTGTGGAGGAGCCAGCAGACACATCCTGTCAGGTAGATACCTCCTGCCAGGGGGACCTGCC
CTTGCACCAGGAAGTGGACTCCTCAGATAGTGAGGTAGCTGTTACTCTCATCGATACTTCTCAACCCGGAGACCCACTGAGTCTACATGA
GCCCATAAAAATTGTTATCACGATGAGCAGTACCCCAAACTCCATGACAGATTTGGAAAGCTCCCTCCACCTGAGGGTGGTTGGCACAGA
GAAGACCAGTGTAAAGTCTGACGCTGAGCCCACTAACCCAGGGGCGGCCGGTTCTCCAAATGCCGAGCAGATCTCAATTCCTGTAATCAC
CCTGGACCTGCCTGAGGGTGGGGGAGGAGGTGTTCCCTGTCCCGAAGGCAATGGAAGTGAAAGGACTCCAGAGAGACTGAAGACGAGGGT
ATCCACCAATCAGTGTTCTGGCTACGGATCTGGGGAGGGGGGAAATGCCATCAAGGATCACAGTTCTTCATCACGGGAACCCTGGGAATC
GGTGTCCCGGCTTACACCTGATACAGGCTCCGAGTCTAAGGTGGGGAAGGAAGGCCAGACTAACCTTGACCCATCGTCTTGTAAGTCCAG
CCATGAAAAGAGGCATGCCCGGGTGCTCAGTGTGGACAGTGGGACAGATGTCTTCTTGAGTAAAAGTTCTGCAGAAATTGTTAACGATAC
AGAGAAAACAATGCCAACTTCCAAATCTGACCTAGAGGCTAAGGAAGGACAAATGCCAAATGAGTCCAACTTCCTGGAATTTGTCTCCCT
GTTAGAATCCATTAATACTTCCAAGATGACGGCATCCAGTCAACTGAATGGCTCAGCTGAGCAGAATGAAGAAAGTGGGCTTCTCCGAGA
TAACTGTTCCCAGGAAAAAAAGGAGGAAATCCTGGAAAATGAAAAGCCCAGTGGACACAGTTCTAAGCAAGGAAAACCAGATTTGCAAAG
TCAAGACCATACTAGCACCGGCCCCGCATGCACTCAGCCTGCCAAGACCACAGCCTTTTTTCAGGGCAATAGACAAAGACAGATAATCTA
CAGGGTAACTTCCCAACAAGATAGTTCTGTCTTGCAAGTCATCAGTGGGCCTGAAACATCTGTACAAGAAGAGATATCTGTGGATGCTAT
GCATGTCTTCATTGATGAACATGGGGAAATTAGATCCTGTTATTTAAAATCTGGAAATCAGAAAGAAGGCCCTTTACAGCCTCTACCATC
AAATAATGACTGTCTCTCTCAGGCTCGAGAGATGCAGGTCAGCTCCTCCAGTACCACAACTTCTGAGAGTCAAGATCCGTCTTCTGGGGA
CCCTGCCGTCAGTGCCCTTCAGCAACAGCTGTTACTGATGGTGGCTCGCAGGACCCAGTCGGAAACCCCACGGAGGCTGCAGTCAGTTCG
GGAAGGCTGTAGGACCCGCAGCCAGTGCAGGCACTCTGGACCTCTCAGGGTGGCGATGAAGTTTCCAGCGCGGAGTACCAGGGGAGCAAC
CAACAAAAAAGCAGAGTCCCGCCAGCCCTCAGAGAATTCTGTGACTGATTCCAACTCCGATTCAGAAGATGAAAGTGGAATGAATTTTTT
GGAGAAAAGGGCTTTAAATATAAAGCAAAACAAAGCAATGCTTGCAAAACTCATGTCTGAATTAGAAAGCTTCCCTGGCTCGTTCCGTGG
AAGACATCCCCTCCCAGGCTCCGACTCACAATCAAGGAGACCGCGAAGGCGTACATTCCCGGGTGTTGCTTCCAGGAGAAACCCTGAACG
GAGAGCTCGTCCTCTTACCAGGTCAAGGTCCCGGATCCTCGGGTCCCTTGACGCTCTACCCATGGAGGAGGAGGAGGAAGAGGATAAGTA
CATGTTGGTGAGAAAGAGGAAGACCGTGGATGGCTACATGAATGAAGATGACCTGCCCAGAAGCCGTCGCTCCAGATCATCCGTGACCCT
TCCGCATATAATTCGCCCAGTGGAAGAAATTACAGAGGAGGAGTTGGAGAACGTCTGCAGCAATTCTCGAGAGAAGATATATAACCGTTC
ACTGGGCTCTACTTGTCATCAATGCCGTCAGAAGACTATTGATACCAAAACAAACTGCAGAAACCCAGACTGCTGGGGCGTTCGAGGCCA
GTTCTGTGGCCCCTGCCTTCGAAACCGTTATGGTGAAGAGGTCAGGGATGCTCTGCTGGATCCGAACTGGCATTGCCCGCCTTGTCGAGG
AATCTGCAACTGCAGTTTCTGCCGGCAGCGAGATGGACGGTGTGCGACTGGGGTCCTTGTGTATTTAGCCAAATATCATGGCTTTGGGAA
TGTGCATGCCTACTTGAAAAGCCTGAAACAGGAATTTGAAATGCAAGCATAATATCTGGAAAATTTGCTGCCTGCCTTCTACTTCTCAAA

>63461_63461_5_PCNXL2-CDCA7_PCNXL2_chr1_233372591_ENST00000258229_CDCA7_chr2_174227954_ENST00000410101_length(amino acids)=1183AA_BP=861
MPGRSSRLRRRGSRVRAEEQLQLQTWGGRRRRGRRRRRRRGRGPRARVLDLREPGDPAGARRVQRGAHQPRGAAGMVSQVLQLLRQGVWA
ALTGGWYHDPEQSKFTNSCHLYLWLFLLLLPLALHLAFPPNAIIVFFYCSAVTIFFTIIKLVSYRLHLMFDKGEVIQQKPSRKEEKPNKD
KEAKGEHITNHRNPSNNRQIHNGKKEEASRNLSTPPLRCSSRGQSITSHHSSGPLELSAQETVEDLKGVILLEDHPIAPVSSTSPGIKVE
SLPASQAHMLETTTKSVIPVKPVATETLINGKGKERGGKGQPPLRHRSEGGLVDKGPLKKLPHLSLSQYDLLETDVSFQPWGSENSVLIP
EPVSCPRGSIRERVQSKSPQDSLSSSCPQCDTIVAKPVEEPADTSCQVDTSCQGDLPLHQEVDSSDSEVAVTLIDTSQPGDPLSLHEPIK
IVITMSSTPNSMTDLESSLHLRVVGTEKTSVKSDAEPTNPGAAGSPNAEQISIPVITLDLPEGGGGGVPCPEGNGSERTPERLKTRVSTN
QCSGYGSGEGGNAIKDHSSSSREPWESVSRLTPDTGSESKVGKEGQTNLDPSSCKSSHEKRHARVLSVDSGTDVFLSKSSAEIVNDTEKT
MPTSKSDLEAKEGQMPNESNFLEFVSLLESINTSKMTASSQLNGSAEQNEESGLLRDNCSQEKKEEILENEKPSGHSSKQGKPDLQSQDH
TSTGPACTQPAKTTAFFQGNRQRQIIYRVTSQQDSSVLQVISGPETSVQEEISVDAMHVFIDEHGEIRSCYLKSGNQKEGPLQPLPSNND
CLSQAREMQVSSSSTTTSESQDPSSGDPAVSALQQQLLLMVARRTQSETPRRLQSVREGCRTRSQCRHSGPLRVAMKFPARSTRGATNKK
AESRQPSENSVTDSNSDSEDESGMNFLEKRALNIKQNKAMLAKLMSELESFPGSFRGRHPLPGSDSQSRRPRRRTFPGVASRRNPERRAR
PLTRSRSRILGSLDALPMEEEEEEDKYMLVRKRKTVDGYMNEDDLPRSRRSRSSVTLPHIIRPVEEITEEELENVCSNSREKIYNRSLGS
TCHQCRQKTIDTKTNCRNPDCWGVRGQFCGPCLRNRYGEEVRDALLDPNWHCPPCRGICNCSFCRQRDGRCATGVLVYLAKYHGFGNVHA

--------------------------------------------------------------

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Fusion Gene PPI Analysis for PCNXL2-CDCA7


check button Go to ChiPPI (Chimeric Protein-Protein interactions) to see the chimeric PPI interaction in

ChiPPI page.


check button Protein-protein interactors with each fusion partner protein in wild-type (BIOGRID-3.4.160)
HgeneHgene's interactorsTgeneTgene's interactors


check button - Retained PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenStill interaction with
TgeneCDCA7chr1:233372591chr2:174227954ENST00000306721210146_170128.0451.0MYC
TgeneCDCA7chr1:233372591chr2:174227954ENST0000034770319146_17049.0372.0MYC
TgeneCDCA7chr1:233372591chr2:174227954ENST0000039256718146_17049.0322.0MYC


check button - Lost PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


check button - Retained PPIs, but lost function due to frame-shift fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


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Related Drugs for PCNXL2-CDCA7


check button Drugs targeting genes involved in this fusion gene.
(DrugBank Version 5.1.8 2021-05-08)
PartnerGeneUniProtAccDrugBank IDDrug nameDrug activityDrug typeDrug status

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Related Diseases for PCNXL2-CDCA7


check button Diseases associated with fusion partners.
(DisGeNet 4.0)
PartnerGeneDisease IDDisease name# pubmedsSource