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	Fusion Gene Summary
	Fusion Gene ORF analysis
	Fusion Genomic Features
	Fusion Protein Features
	Fusion Gene Sequence
	Fusion Gene PPI analysis
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Fusion gene:PCNXL2-TAOK3 (FusionGDB2 ID:63465)

Fusion Gene Summary for PCNXL2-TAOK3

Fusion gene summary

Fusion gene information	Fusion gene name: PCNXL2-TAOK3
	Fusion gene ID: 63465
		Hgene	Tgene
	Gene symbol	PCNXL2	TAOK3
	Gene ID	80003	51347
	Gene name	pecanex 2	TAO kinase 3
	Synonyms	PCNXL2	DPK\|JIK\|MAP3K18\|hKFC-A
	Cytomap	1q42.2	12q24.23
	Type of gene	protein-coding	protein-coding
	Description	pecanex-like protein 2pecanex homolog 2	serine/threonine-protein kinase TAO3CTCL-associated antigen HD-CL-09JNK/SAPK-inhibitory kinaseSTE20-like kinasecutaneous T-cell lymphoma-associated antigen HD-CL-09dendritic cell-derived protein kinasejun kinase-inhibitory kinasekinase from chicken
	Modification date	20200313	20200313
	UniProtAcc	.	.
	Ensembl transtripts involved in fusion gene	ENST00000258229, ENST00000520463, ENST00000344698, ENST00000430153, ENST00000488780,	ENST00000536979, ENST00000537952, ENST00000543709, ENST00000392533, ENST00000419821,
Fusion gene scores	* DoF score	5 X 5 X 3=75	13 X 15 X 5=975
	# samples	5	16
	** MAII score	log2(5/75*10)=-0.584962500721156 possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs). DoF>8 and MAII<0	log2(16/975*10)=-2.60733031374961 possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs). DoF>8 and MAII<0
Context	PubMed: PCNXL2 [Title/Abstract] AND TAOK3 [Title/Abstract] AND fusion [Title/Abstract]
Most frequent breakpoint	PCNXL2(233270759)-TAOK3(118639268), # samples:2
Anticipated loss of major functional domain due to fusion event.

* DoF score (Degree of Frequency) = # partners X # break points X # cancer types
** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10)

Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez

Partner	Gene	GO ID	GO term	PubMed ID
Tgene	TAOK3	GO:0006468	protein phosphorylation	10559204
Tgene	TAOK3	GO:0006974	cellular response to DNA damage stimulus	17396146
Tgene	TAOK3	GO:0046329	negative regulation of JNK cascade	10559204
Tgene	TAOK3	GO:0046777	protein autophosphorylation	10559204

Fusion gene breakpoints across PCNXL2 (5'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.

Fusion gene breakpoints across TAOK3 (3'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.

Fusion gene information from two resources (ChiTars 5.0 and ChimerDB 4.0)
* All genome coordinats were lifted-over on hg19.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.

Source	Disease	Sample	Hgene	Hchr	Hbp	Hstrand	Tgene	Tchr	Tbp	Tstrand
ChimerDB4	BRCA	TCGA-AR-A1AH-01A	PCNXL2	chr1	233270759	-	TAOK3	chr12	118639268	-
ChimerDB4	BRCA	TCGA-AR-A1AH-01A	PCNXL2	chr1	233270761	-	TAOK3	chr12	118639270	-

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Fusion Gene ORF analysis for PCNXL2-TAOK3

Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.

ORF	Henst	Tenst	Hgene	Hchr	Hbp	Hstrand	Tgene	Tchr	Tbp	Tstrand
5CDS-intron	ENST00000258229	ENST00000536979	PCNXL2	chr1	233270759	-	TAOK3	chr12	118639268	-
5CDS-intron	ENST00000258229	ENST00000536979	PCNXL2	chr1	233270761	-	TAOK3	chr12	118639270	-
5CDS-intron	ENST00000258229	ENST00000537952	PCNXL2	chr1	233270759	-	TAOK3	chr12	118639268	-
5CDS-intron	ENST00000258229	ENST00000537952	PCNXL2	chr1	233270761	-	TAOK3	chr12	118639270	-
5CDS-intron	ENST00000258229	ENST00000543709	PCNXL2	chr1	233270759	-	TAOK3	chr12	118639268	-
5CDS-intron	ENST00000258229	ENST00000543709	PCNXL2	chr1	233270761	-	TAOK3	chr12	118639270	-
5UTR-3CDS	ENST00000520463	ENST00000392533	PCNXL2	chr1	233270759	-	TAOK3	chr12	118639268	-
5UTR-3CDS	ENST00000520463	ENST00000392533	PCNXL2	chr1	233270761	-	TAOK3	chr12	118639270	-
5UTR-3CDS	ENST00000520463	ENST00000419821	PCNXL2	chr1	233270759	-	TAOK3	chr12	118639268	-
5UTR-3CDS	ENST00000520463	ENST00000419821	PCNXL2	chr1	233270761	-	TAOK3	chr12	118639270	-
5UTR-intron	ENST00000520463	ENST00000536979	PCNXL2	chr1	233270759	-	TAOK3	chr12	118639268	-
5UTR-intron	ENST00000520463	ENST00000536979	PCNXL2	chr1	233270761	-	TAOK3	chr12	118639270	-
5UTR-intron	ENST00000520463	ENST00000537952	PCNXL2	chr1	233270759	-	TAOK3	chr12	118639268	-
5UTR-intron	ENST00000520463	ENST00000537952	PCNXL2	chr1	233270761	-	TAOK3	chr12	118639270	-
5UTR-intron	ENST00000520463	ENST00000543709	PCNXL2	chr1	233270759	-	TAOK3	chr12	118639268	-
5UTR-intron	ENST00000520463	ENST00000543709	PCNXL2	chr1	233270761	-	TAOK3	chr12	118639270	-
In-frame	ENST00000258229	ENST00000392533	PCNXL2	chr1	233270759	-	TAOK3	chr12	118639268	-
In-frame	ENST00000258229	ENST00000392533	PCNXL2	chr1	233270761	-	TAOK3	chr12	118639270	-
In-frame	ENST00000258229	ENST00000419821	PCNXL2	chr1	233270759	-	TAOK3	chr12	118639268	-
In-frame	ENST00000258229	ENST00000419821	PCNXL2	chr1	233270761	-	TAOK3	chr12	118639270	-
intron-3CDS	ENST00000344698	ENST00000392533	PCNXL2	chr1	233270759	-	TAOK3	chr12	118639268	-
intron-3CDS	ENST00000344698	ENST00000392533	PCNXL2	chr1	233270761	-	TAOK3	chr12	118639270	-
intron-3CDS	ENST00000344698	ENST00000419821	PCNXL2	chr1	233270759	-	TAOK3	chr12	118639268	-
intron-3CDS	ENST00000344698	ENST00000419821	PCNXL2	chr1	233270761	-	TAOK3	chr12	118639270	-
intron-3CDS	ENST00000430153	ENST00000392533	PCNXL2	chr1	233270759	-	TAOK3	chr12	118639268	-
intron-3CDS	ENST00000430153	ENST00000392533	PCNXL2	chr1	233270761	-	TAOK3	chr12	118639270	-
intron-3CDS	ENST00000430153	ENST00000419821	PCNXL2	chr1	233270759	-	TAOK3	chr12	118639268	-
intron-3CDS	ENST00000430153	ENST00000419821	PCNXL2	chr1	233270761	-	TAOK3	chr12	118639270	-
intron-3CDS	ENST00000488780	ENST00000392533	PCNXL2	chr1	233270759	-	TAOK3	chr12	118639268	-
intron-3CDS	ENST00000488780	ENST00000392533	PCNXL2	chr1	233270761	-	TAOK3	chr12	118639270	-
intron-3CDS	ENST00000488780	ENST00000419821	PCNXL2	chr1	233270759	-	TAOK3	chr12	118639268	-
intron-3CDS	ENST00000488780	ENST00000419821	PCNXL2	chr1	233270761	-	TAOK3	chr12	118639270	-
intron-intron	ENST00000344698	ENST00000536979	PCNXL2	chr1	233270759	-	TAOK3	chr12	118639268	-
intron-intron	ENST00000344698	ENST00000536979	PCNXL2	chr1	233270761	-	TAOK3	chr12	118639270	-
intron-intron	ENST00000344698	ENST00000537952	PCNXL2	chr1	233270759	-	TAOK3	chr12	118639268	-
intron-intron	ENST00000344698	ENST00000537952	PCNXL2	chr1	233270761	-	TAOK3	chr12	118639270	-
intron-intron	ENST00000344698	ENST00000543709	PCNXL2	chr1	233270759	-	TAOK3	chr12	118639268	-
intron-intron	ENST00000344698	ENST00000543709	PCNXL2	chr1	233270761	-	TAOK3	chr12	118639270	-
intron-intron	ENST00000430153	ENST00000536979	PCNXL2	chr1	233270759	-	TAOK3	chr12	118639268	-
intron-intron	ENST00000430153	ENST00000536979	PCNXL2	chr1	233270761	-	TAOK3	chr12	118639270	-
intron-intron	ENST00000430153	ENST00000537952	PCNXL2	chr1	233270759	-	TAOK3	chr12	118639268	-
intron-intron	ENST00000430153	ENST00000537952	PCNXL2	chr1	233270761	-	TAOK3	chr12	118639270	-
intron-intron	ENST00000430153	ENST00000543709	PCNXL2	chr1	233270759	-	TAOK3	chr12	118639268	-
intron-intron	ENST00000430153	ENST00000543709	PCNXL2	chr1	233270761	-	TAOK3	chr12	118639270	-
intron-intron	ENST00000488780	ENST00000536979	PCNXL2	chr1	233270759	-	TAOK3	chr12	118639268	-
intron-intron	ENST00000488780	ENST00000536979	PCNXL2	chr1	233270761	-	TAOK3	chr12	118639270	-
intron-intron	ENST00000488780	ENST00000537952	PCNXL2	chr1	233270759	-	TAOK3	chr12	118639268	-
intron-intron	ENST00000488780	ENST00000537952	PCNXL2	chr1	233270761	-	TAOK3	chr12	118639270	-
intron-intron	ENST00000488780	ENST00000543709	PCNXL2	chr1	233270759	-	TAOK3	chr12	118639268	-
intron-intron	ENST00000488780	ENST00000543709	PCNXL2	chr1	233270761	-	TAOK3	chr12	118639270	-

ORFfinder result based on the fusion transcript sequence of in-frame fusion genes.

Henst	Tenst	Hgene	Hchr	Hbp	Hstrand	Tgene	Tchr	Tbp	Tstrand	Seq length (transcript)	BP loci (transcript)	Predicted start (transcript)	Predicted stop (transcript)	Seq length (amino acids)
ENST00000258229	PCNXL2	chr1	233270761	-	ENST00000419821	TAOK3	chr12	118639270	-	7146	4072	10	5949	1979
ENST00000258229	PCNXL2	chr1	233270761	-	ENST00000392533	TAOK3	chr12	118639270	-	7146	4072	10	5949	1979
ENST00000258229	PCNXL2	chr1	233270759	-	ENST00000419821	TAOK3	chr12	118639268	-	7146	4072	10	5949	1979
ENST00000258229	PCNXL2	chr1	233270759	-	ENST00000392533	TAOK3	chr12	118639268	-	7146	4072	10	5949	1979

DeepORF prediction of the coding potential based on the fusion transcript sequence of in-frame fusion genes. DeepORF is a coding potential classifier based on convolutional neural network by comparing the real Ribo-seq data. If the no-coding score < 0.5 and coding score > 0.5, then the in-frame fusion transcript is predicted as being likely translated.

Henst	Tenst	Hgene	Hchr	Hbp	Hstrand	Tgene	Tchr	Tbp	Tstrand	No-coding score	Coding score
ENST00000258229	ENST00000419821	PCNXL2	chr1	233270761	-	TAOK3	chr12	118639270	-	0.0004002	0.9995999
ENST00000258229	ENST00000392533	PCNXL2	chr1	233270761	-	TAOK3	chr12	118639270	-	0.0004002	0.9995999
ENST00000258229	ENST00000419821	PCNXL2	chr1	233270759	-	TAOK3	chr12	118639268	-	0.0004002	0.9995999
ENST00000258229	ENST00000392533	PCNXL2	chr1	233270759	-	TAOK3	chr12	118639268	-	0.0004002	0.9995999

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Fusion Genomic Features for PCNXL2-TAOK3

FusionAI prediction of the potential fusion gene breakpoint based on the pre-mature RNA sequence context (+/- 5kb of individual partner genes, total 20kb length sequence). FusionAI is a fusion gene breakpoint classifier based on convolutional neural network by comparing the fusion positive and negative sequence context of ~ 20K fusion gene data. From here, we can have the relative potentency of the 20K genomic sequence how individual sequnce will be likely used as the gene fusion breakpoints.

Hgene

Hchr

Hbp

Hstrand

Tgene

Tchr

Tbp

Tstrand

1-p

p (fusion gene breakpoint)

Distribution of 44 human genomic features loci across 20kb length fusion breakpoint regions. We integrated a total of 44 different types of human genomic feature loci information across five big categories including virus integration sites, repeats, structural variants, chromatin states, and gene expression regulation. More details are in help page.

Distribution of 44 human genomic features loci across 20kb length fusion breakpoint regions that are ovelapped with the top 1% feature importance score regions. More details are in help page.

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Fusion Protein Features for PCNXL2-TAOK3

Four levels of functional features of fusion genes
Go to FGviewer search page for the most frequent breakpoint (https://ccsmweb.uth.edu/FGviewer/chr1:233270759/chr12:118639268)
- FGviewer provides the online visualization of the retention search of the protein functional features across DNA, RNA, protein, and pathological levels.
- How to search
1. Put your fusion gene symbol.
2. Press the tab key until there will be shown the breakpoint information filled.
4. Go down and press 'Search' tab twice.
4. Go down to have the hyperlink of the search result.
5. Click the hyperlink.
6. See the FGviewer result for your fusion gene.

Main function of each fusion partner protein. (from UniProt)

Hgene	Tgene
.	.
FUNCTION: Transcriptional activator which is required for calcium-dependent dendritic growth and branching in cortical neurons. Recruits CREB-binding protein (CREBBP) to nuclear bodies. Component of the CREST-BRG1 complex, a multiprotein complex that regulates promoter activation by orchestrating a calcium-dependent release of a repressor complex and a recruitment of an activator complex. In resting neurons, transcription of the c-FOS promoter is inhibited by BRG1-dependent recruitment of a phospho-RB1-HDAC1 repressor complex. Upon calcium influx, RB1 is dephosphorylated by calcineurin, which leads to release of the repressor complex. At the same time, there is increased recruitment of CREBBP to the promoter by a CREST-dependent mechanism, which leads to transcriptional activation. The CREST-BRG1 complex also binds to the NR2B promoter, and activity-dependent induction of NR2B expression involves a release of HDAC1 and recruitment of CREBBP (By similarity). {ECO:0000250}.	FUNCTION: Transcriptional activator which is required for calcium-dependent dendritic growth and branching in cortical neurons. Recruits CREB-binding protein (CREBBP) to nuclear bodies. Component of the CREST-BRG1 complex, a multiprotein complex that regulates promoter activation by orchestrating a calcium-dependent release of a repressor complex and a recruitment of an activator complex. In resting neurons, transcription of the c-FOS promoter is inhibited by BRG1-dependent recruitment of a phospho-RB1-HDAC1 repressor complex. Upon calcium influx, RB1 is dephosphorylated by calcineurin, which leads to release of the repressor complex. At the same time, there is increased recruitment of CREBBP to the promoter by a CREST-dependent mechanism, which leads to transcriptional activation. The CREST-BRG1 complex also binds to the NR2B promoter, and activity-dependent induction of NR2B expression involves a release of HDAC1 and recruitment of CREBBP (By similarity). {ECO:0000250}.

Retention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at
download page

* Minus value of BPloci means that the break pointn is located before the CDS.

- In-frame and retained protein feature among the 13 regional features.

Partner

Gene

Hbp

Tbp

ENST

Strand

BPexon

TotalExon

Protein feature loci

*BPloci

TotalLen

Protein feature

Protein feature note

Hgene

PCNXL2

chr1:233270759

chr12:118639268

ENST00000258229

1029_1049

1279

2138.0

Transmembrane

Helical

Hgene

PCNXL2

chr1:233270759

chr12:118639268

ENST00000258229

1099_1119

1279

2138.0

Transmembrane

Helical

Hgene

PCNXL2

chr1:233270759

chr12:118639268

ENST00000258229

1124_1144

1279

2138.0

Transmembrane

Helical

Hgene

PCNXL2

chr1:233270759

chr12:118639268

ENST00000258229

1193_1213

1279

2138.0

Transmembrane

Helical

Hgene

PCNXL2

chr1:233270759

chr12:118639268

ENST00000258229

1237_1257

1279

2138.0

Transmembrane

Helical

Hgene

PCNXL2

chr1:233270759

chr12:118639268

ENST00000258229

34_54

1279

2138.0

Transmembrane

Helical

Hgene

PCNXL2

chr1:233270759

chr12:118639268

ENST00000258229

57_77

1279

2138.0

Transmembrane

Helical

Hgene

PCNXL2

chr1:233270759

chr12:118639268

ENST00000258229

844_864

1279

2138.0

Transmembrane

Helical

Hgene

PCNXL2

chr1:233270759

chr12:118639268

ENST00000258229

868_888

1279

2138.0

Transmembrane

Helical

Hgene

PCNXL2

chr1:233270759

chr12:118639268

ENST00000258229

901_921

1279

2138.0

Transmembrane

Helical

Hgene

PCNXL2

chr1:233270759

chr12:118639268

ENST00000258229

952_972

1279

2138.0

Transmembrane

Helical

Hgene

PCNXL2

chr1:233270759

chr12:118639268

ENST00000258229

983_1003

1279

2138.0

Transmembrane

Helical

Hgene

PCNXL2

chr1:233270761

chr12:118639270

ENST00000258229

1029_1049

1279

2138.0

Transmembrane

Helical

Hgene

PCNXL2

chr1:233270761

chr12:118639270

ENST00000258229

1099_1119

1279

2138.0

Transmembrane

Helical

Hgene

PCNXL2

chr1:233270761

chr12:118639270

ENST00000258229

1124_1144

1279

2138.0

Transmembrane

Helical

Hgene

PCNXL2

chr1:233270761

chr12:118639270

ENST00000258229

1193_1213

1279

2138.0

Transmembrane

Helical

Hgene

PCNXL2

chr1:233270761

chr12:118639270

ENST00000258229

1237_1257

1279

2138.0

Transmembrane

Helical

Hgene

PCNXL2

chr1:233270761

chr12:118639270

ENST00000258229

34_54

1279

2138.0

Transmembrane

Helical

Hgene

PCNXL2

chr1:233270761

chr12:118639270

ENST00000258229

57_77

1279

2138.0

Transmembrane

Helical

Hgene

PCNXL2

chr1:233270761

chr12:118639270

ENST00000258229

844_864

1279

2138.0

Transmembrane

Helical

Hgene

PCNXL2

chr1:233270761

chr12:118639270

ENST00000258229

868_888

1279

2138.0

Transmembrane

Helical

Hgene

PCNXL2

chr1:233270761

chr12:118639270

ENST00000258229

901_921

1279

2138.0

Transmembrane

Helical

Hgene

PCNXL2

chr1:233270761

chr12:118639270

ENST00000258229

952_972

1279

2138.0

Transmembrane

Helical

Hgene

PCNXL2

chr1:233270761

chr12:118639270

ENST00000258229

983_1003

1279

2138.0

Transmembrane

Helical

Tgene

TAOK3

chr1:233270759

chr12:118639268

ENST00000392533

452_502

273

899.0

Coiled coil

Ontology_term=ECO:0000255

Tgene

TAOK3

chr1:233270759

chr12:118639268

ENST00000392533

548_649

273

899.0

Coiled coil

Ontology_term=ECO:0000255

Tgene

TAOK3

chr1:233270759

chr12:118639268

ENST00000392533

754_879

273

899.0

Coiled coil

Ontology_term=ECO:0000255

Tgene

TAOK3

chr1:233270759

chr12:118639268

ENST00000419821

452_502

273

899.0

Coiled coil

Ontology_term=ECO:0000255

Tgene

TAOK3

chr1:233270759

chr12:118639268

ENST00000419821

548_649

273

899.0

Coiled coil

Ontology_term=ECO:0000255

Tgene

TAOK3

chr1:233270759

chr12:118639268

ENST00000419821

754_879

273

899.0

Coiled coil

Ontology_term=ECO:0000255

Tgene

TAOK3

chr1:233270761

chr12:118639270

ENST00000392533

452_502

273

899.0

Coiled coil

Ontology_term=ECO:0000255

Tgene

TAOK3

chr1:233270761

chr12:118639270

ENST00000392533

548_649

273

899.0

Coiled coil

Ontology_term=ECO:0000255

Tgene

TAOK3

chr1:233270761

chr12:118639270

ENST00000392533

754_879

273

899.0

Coiled coil

Ontology_term=ECO:0000255

Tgene

TAOK3

chr1:233270761

chr12:118639270

ENST00000419821

452_502

273

899.0

Coiled coil

Ontology_term=ECO:0000255

Tgene

TAOK3

chr1:233270761

chr12:118639270

ENST00000419821

548_649

273

899.0

Coiled coil

Ontology_term=ECO:0000255

Tgene

TAOK3

chr1:233270761

chr12:118639270

ENST00000419821

754_879

273

899.0

Coiled coil

Ontology_term=ECO:0000255

Tgene

TAOK3

chr1:233270759

chr12:118639268

ENST00000392533

343_393

273

899.0

Compositional bias

Note=Ser-rich

Tgene

TAOK3

chr1:233270759

chr12:118639268

ENST00000419821

343_393

273

899.0

Compositional bias

Note=Ser-rich

Tgene

TAOK3

chr1:233270761

chr12:118639270

ENST00000392533

343_393

273

899.0

Compositional bias

Note=Ser-rich

Tgene

TAOK3

chr1:233270761

chr12:118639270

ENST00000419821

343_393

273

899.0

Compositional bias

Note=Ser-rich

- In-frame and not-retained protein feature among the 13 regional features.

Partner

Gene

Hbp

Tbp

ENST

Strand

BPexon

TotalExon

Protein feature loci

*BPloci

TotalLen

Protein feature

Protein feature note

Hgene

PCNXL2

chr1:233270759

chr12:118639268

ENST00000258229

1937_2063

1279

2138.0

Compositional bias

Note=Ser-rich

Hgene

PCNXL2

chr1:233270759

chr12:118639268

ENST00000344698

1937_2063

778.0

Compositional bias

Note=Ser-rich

Hgene

PCNXL2

chr1:233270759

chr12:118639268

ENST00000430153

1937_2063

287.0

Compositional bias

Note=Ser-rich

Hgene

PCNXL2

chr1:233270761

chr12:118639270

ENST00000258229

1937_2063

1279

2138.0

Compositional bias

Note=Ser-rich

Hgene

PCNXL2

chr1:233270761

chr12:118639270

ENST00000344698

1937_2063

778.0

Compositional bias

Note=Ser-rich

Hgene

PCNXL2

chr1:233270761

chr12:118639270

ENST00000430153

1937_2063

287.0

Compositional bias

Note=Ser-rich

Hgene

PCNXL2

chr1:233270759

chr12:118639268

ENST00000258229

1265_1285

1279

2138.0

Transmembrane

Helical

Hgene

PCNXL2

chr1:233270759

chr12:118639268

ENST00000258229

1302_1322

1279

2138.0

Transmembrane

Helical

Hgene

PCNXL2

chr1:233270759

chr12:118639268

ENST00000258229

1324_1344

1279

2138.0

Transmembrane

Helical

Hgene

PCNXL2

chr1:233270759

chr12:118639268

ENST00000344698

1029_1049

778.0

Transmembrane

Helical

Hgene

PCNXL2

chr1:233270759

chr12:118639268

ENST00000344698

1099_1119

778.0

Transmembrane

Helical

Hgene

PCNXL2

chr1:233270759

chr12:118639268

ENST00000344698

1124_1144

778.0

Transmembrane

Helical

Hgene

PCNXL2

chr1:233270759

chr12:118639268

ENST00000344698

1193_1213

778.0

Transmembrane

Helical

Hgene

PCNXL2

chr1:233270759

chr12:118639268

ENST00000344698

1237_1257

778.0

Transmembrane

Helical

Hgene

PCNXL2

chr1:233270759

chr12:118639268

ENST00000344698

1265_1285

778.0

Transmembrane

Helical

Hgene

PCNXL2

chr1:233270759

chr12:118639268

ENST00000344698

1302_1322

778.0

Transmembrane

Helical

Hgene

PCNXL2

chr1:233270759

chr12:118639268

ENST00000344698

1324_1344

778.0

Transmembrane

Helical

Hgene

PCNXL2

chr1:233270759

chr12:118639268

ENST00000344698

34_54

778.0

Transmembrane

Helical

Hgene

PCNXL2

chr1:233270759

chr12:118639268

ENST00000344698

57_77

778.0

Transmembrane

Helical

Hgene

PCNXL2

chr1:233270759

chr12:118639268

ENST00000344698

844_864

778.0

Transmembrane

Helical

Hgene

PCNXL2

chr1:233270759

chr12:118639268

ENST00000344698

868_888

778.0

Transmembrane

Helical

Hgene

PCNXL2

chr1:233270759

chr12:118639268

ENST00000344698

901_921

778.0

Transmembrane

Helical

Hgene

PCNXL2

chr1:233270759

chr12:118639268

ENST00000344698

952_972

778.0

Transmembrane

Helical

Hgene

PCNXL2

chr1:233270759

chr12:118639268

ENST00000344698

983_1003

778.0

Transmembrane

Helical

Hgene

PCNXL2

chr1:233270759

chr12:118639268

ENST00000430153

1029_1049

287.0

Transmembrane

Helical

Hgene

PCNXL2

chr1:233270759

chr12:118639268

ENST00000430153

1099_1119

287.0

Transmembrane

Helical

Hgene

PCNXL2

chr1:233270759

chr12:118639268

ENST00000430153

1124_1144

287.0

Transmembrane

Helical

Hgene

PCNXL2

chr1:233270759

chr12:118639268

ENST00000430153

1193_1213

287.0

Transmembrane

Helical

Hgene

PCNXL2

chr1:233270759

chr12:118639268

ENST00000430153

1237_1257

287.0

Transmembrane

Helical

Hgene

PCNXL2

chr1:233270759

chr12:118639268

ENST00000430153

1265_1285

287.0

Transmembrane

Helical

Hgene

PCNXL2

chr1:233270759

chr12:118639268

ENST00000430153

1302_1322

287.0

Transmembrane

Helical

Hgene

PCNXL2

chr1:233270759

chr12:118639268

ENST00000430153

1324_1344

287.0

Transmembrane

Helical

Hgene

PCNXL2

chr1:233270759

chr12:118639268

ENST00000430153

34_54

287.0

Transmembrane

Helical

Hgene

PCNXL2

chr1:233270759

chr12:118639268

ENST00000430153

57_77

287.0

Transmembrane

Helical

Hgene

PCNXL2

chr1:233270759

chr12:118639268

ENST00000430153

844_864

287.0

Transmembrane

Helical

Hgene

PCNXL2

chr1:233270759

chr12:118639268

ENST00000430153

868_888

287.0

Transmembrane

Helical

Hgene

PCNXL2

chr1:233270759

chr12:118639268

ENST00000430153

901_921

287.0

Transmembrane

Helical

Hgene

PCNXL2

chr1:233270759

chr12:118639268

ENST00000430153

952_972

287.0

Transmembrane

Helical

Hgene

PCNXL2

chr1:233270759

chr12:118639268

ENST00000430153

983_1003

287.0

Transmembrane

Helical

Hgene

PCNXL2

chr1:233270761

chr12:118639270

ENST00000258229

1265_1285

1279

2138.0

Transmembrane

Helical

Hgene

PCNXL2

chr1:233270761

chr12:118639270

ENST00000258229

1302_1322

1279

2138.0

Transmembrane

Helical

Hgene

PCNXL2

chr1:233270761

chr12:118639270

ENST00000258229

1324_1344

1279

2138.0

Transmembrane

Helical

Hgene

PCNXL2

chr1:233270761

chr12:118639270

ENST00000344698

1029_1049

778.0

Transmembrane

Helical

Hgene

PCNXL2

chr1:233270761

chr12:118639270

ENST00000344698

1099_1119

778.0

Transmembrane

Helical

Hgene

PCNXL2

chr1:233270761

chr12:118639270

ENST00000344698

1124_1144

778.0

Transmembrane

Helical

Hgene

PCNXL2

chr1:233270761

chr12:118639270

ENST00000344698

1193_1213

778.0

Transmembrane

Helical

Hgene

PCNXL2

chr1:233270761

chr12:118639270

ENST00000344698

1237_1257

778.0

Transmembrane

Helical

Hgene

PCNXL2

chr1:233270761

chr12:118639270

ENST00000344698

1265_1285

778.0

Transmembrane

Helical

Hgene

PCNXL2

chr1:233270761

chr12:118639270

ENST00000344698

1302_1322

778.0

Transmembrane

Helical

Hgene

PCNXL2

chr1:233270761

chr12:118639270

ENST00000344698

1324_1344

778.0

Transmembrane

Helical

Hgene

PCNXL2

chr1:233270761

chr12:118639270

ENST00000344698

34_54

778.0

Transmembrane

Helical

Hgene

PCNXL2

chr1:233270761

chr12:118639270

ENST00000344698

57_77

778.0

Transmembrane

Helical

Hgene

PCNXL2

chr1:233270761

chr12:118639270

ENST00000344698

844_864

778.0

Transmembrane

Helical

Hgene

PCNXL2

chr1:233270761

chr12:118639270

ENST00000344698

868_888

778.0

Transmembrane

Helical

Hgene

PCNXL2

chr1:233270761

chr12:118639270

ENST00000344698

901_921

778.0

Transmembrane

Helical

Hgene

PCNXL2

chr1:233270761

chr12:118639270

ENST00000344698

952_972

778.0

Transmembrane

Helical

Hgene

PCNXL2

chr1:233270761

chr12:118639270

ENST00000344698

983_1003

778.0

Transmembrane

Helical

Hgene

PCNXL2

chr1:233270761

chr12:118639270

ENST00000430153

1029_1049

287.0

Transmembrane

Helical

Hgene

PCNXL2

chr1:233270761

chr12:118639270

ENST00000430153

1099_1119

287.0

Transmembrane

Helical

Hgene

PCNXL2

chr1:233270761

chr12:118639270

ENST00000430153

1124_1144

287.0

Transmembrane

Helical

Hgene

PCNXL2

chr1:233270761

chr12:118639270

ENST00000430153

1193_1213

287.0

Transmembrane

Helical

Hgene

PCNXL2

chr1:233270761

chr12:118639270

ENST00000430153

1237_1257

287.0

Transmembrane

Helical

Hgene

PCNXL2

chr1:233270761

chr12:118639270

ENST00000430153

1265_1285

287.0

Transmembrane

Helical

Hgene

PCNXL2

chr1:233270761

chr12:118639270

ENST00000430153

1302_1322

287.0

Transmembrane

Helical

Hgene

PCNXL2

chr1:233270761

chr12:118639270

ENST00000430153

1324_1344

287.0

Transmembrane

Helical

Hgene

PCNXL2

chr1:233270761

chr12:118639270

ENST00000430153

34_54

287.0

Transmembrane

Helical

Hgene

PCNXL2

chr1:233270761

chr12:118639270

ENST00000430153

57_77

287.0

Transmembrane

Helical

Hgene

PCNXL2

chr1:233270761

chr12:118639270

ENST00000430153

844_864

287.0

Transmembrane

Helical

Hgene

PCNXL2

chr1:233270761

chr12:118639270

ENST00000430153

868_888

287.0

Transmembrane

Helical

Hgene

PCNXL2

chr1:233270761

chr12:118639270

ENST00000430153

901_921

287.0

Transmembrane

Helical

Hgene

PCNXL2

chr1:233270761

chr12:118639270

ENST00000430153

952_972

287.0

Transmembrane

Helical

Hgene

PCNXL2

chr1:233270761

chr12:118639270

ENST00000430153

983_1003

287.0

Transmembrane

Helical

Tgene

TAOK3

chr1:233270759

chr12:118639268

ENST00000392533

24_277

273

899.0

Domain

Protein kinase

Tgene

TAOK3

chr1:233270759

chr12:118639268

ENST00000419821

24_277

273

899.0

Domain

Protein kinase

Tgene

TAOK3

chr1:233270761

chr12:118639270

ENST00000392533

24_277

273

899.0

Domain

Protein kinase

Tgene

TAOK3

chr1:233270761

chr12:118639270

ENST00000419821

24_277

273

899.0

Domain

Protein kinase

Tgene

TAOK3

chr1:233270759

chr12:118639268

ENST00000392533

30_38

273

899.0

Nucleotide binding

ATP

Tgene

TAOK3

chr1:233270759

chr12:118639268

ENST00000419821

30_38

273

899.0

Nucleotide binding

ATP

Tgene

TAOK3

chr1:233270761

chr12:118639270

ENST00000392533

30_38

273

899.0

Nucleotide binding

ATP

Tgene

TAOK3

chr1:233270761

chr12:118639270

ENST00000419821

30_38

273

899.0

Nucleotide binding

ATP

Top

Fusion Gene Sequence for PCNXL2-TAOK3

For in-frame fusion transcripts, we provide the fusion transcript sequences and fusion amino acid sequences. To have fusion amino acid sequence, we ran ORFfinder and chose the longest ORF among the all predicted ones.

>63465_63465_1_PCNXL2-TAOK3_PCNXL2_chr1_233270759_ENST00000258229_TAOK3_chr12_118639268_ENST00000392533_length(transcript)=7146nt_BP=4072nt
TGGCGCTCACCTGCCCGGCCGCAGCAGCCGGCTCCGGCGCCGCGGTTCGCGGGTCCGGGCGGAAGAGCAGCTCCAGCTTCAAACGTGGGG
TGGAAGGAGGCGGCGGGGGCGACGGCGGCGGCGACGGCGGGGGCGCGGCCCGCGGGCCCGGGTGTTAGACCTGAGGGAGCCTGGAGATCC
GGCCGGGGCGCGCAGGGTGCAGCGGGGCGCTCACCAGCCCCGGGGCGCAGCCGGCATGGTGTCCCAGGTGCTGCAGCTGCTCCGGCAGGG
CGTGTGGGCCGCGCTCACCGGGGGCTGGTACCACGACCCGGAGCAGAGCAAGTTCACCAACAGCTGCCACCTCTACCTGTGGCTGTTCCT
CCTGCTGCTGCCCCTGGCCCTGCACCTGGCTTTTCCTCCAAATGCGATCATTGTATTTTTCTACTGCAGTGCAGTGACTATATTCTTCAC
AATAATCAAACTGGTCAGTTATCGCCTACACCTCATGTTTGACAAAGGAGAAGTAATTCAGCAAAAGCCCTCCAGAAAGGAAGAAAAGCC
AAATAAAGACAAGGAGGCCAAAGGTGAACACATAACTAATCACAGAAATCCAAGCAATAATAGGCAGATTCACAATGGCAAAAAGGAAGA
GGCCAGTCGAAACCTCTCCACGCCTCCCCTCCGCTGCAGCTCCAGAGGGCAAAGCATAACCTCTCATCACTCTTCTGGGCCATTGGAGTT
GTCAGCACAGGAAACTGTAGAAGATCTCAAAGGTGTCATTCTATTAGAAGACCATCCCATAGCACCAGTGTCATCTACCTCACCTGGTAT
CAAAGTGGAAAGCTTACCTGCGTCTCAAGCACACATGCTGGAAACCACGACCAAGTCAGTAATACCTGTAAAACCAGTTGCCACAGAAAC
TCTCATCAATGGTAAAGGAAAGGAAAGAGGAGGCAAGGGGCAGCCTCCTTTGCGCCACAGATCCGAGGGTGGCTTAGTGGATAAGGGACC
CTTGAAGAAGTTGCCCCACCTGTCTTTGTCTCAGTATGACTTACTAGAAACAGACGTTTCTTTCCAGCCGTGGGGGAGTGAGAATTCAGT
CCTGATTCCAGAACCTGTCAGTTGTCCCCGGGGCTCCATAAGGGAACGGGTACAAAGCAAGTCACCTCAGGACAGCCTGAGCAGCAGCTG
CCCTCAATGTGACACCATCGTGGCCAAGCCTGTGGAGGAGCCAGCAGACACATCCTGTCAGGTAGATACCTCCTGCCAGGGGGACCTGCC
CTTGCACCAGGAAGTGGACTCCTCAGATAGTGAGGTAGCTGTTACTCTCATCGATACTTCTCAACCCGGAGACCCACTGAGTCTACATGA
GCCCATAAAAATTGTTATCACGATGAGCAGTACCCCAAACTCCATGACAGATTTGGAAAGCTCCCTCCACCTGAGGGTGGTTGGCACAGA
GAAGACCAGTGTAAAGTCTGACGCTGAGCCCACTAACCCAGGGGCGGCCGGTTCTCCAAATGCCGAGCAGATCTCAATTCCTGTAATCAC
CCTGGACCTGCCTGAGGGTGGGGGAGGAGGTGTTCCCTGTCCCGAAGGCAATGGAAGTGAAAGGACTCCAGAGAGACTGAAGACGAGGGT
ATCCACCAATCAGTGTTCTGGCTACGGATCTGGGGAGGGGGGAAATGCCATCAAGGATCACAGTTCTTCATCACGGGAACCCTGGGAATC
GGTGTCCCGGCTTACACCTGATACAGGCTCCGAGTCTAAGGTGGGGAAGGAAGGCCAGACTAACCTTGACCCATCGTCTTGTAAGTCCAG
CCATGAAAAGAGGCATGCCCGGGTGCTCAGTGTGGACAGTGGGACAGATGTCTTCTTGAGTAAAAGTTCTGCAGAAATTGTTAACGATAC
AGAGAAAACAATGCCAACTTCCAAATCTGACCTAGAGGCTAAGGAAGGACAAATGCCAAATGAGTCCAACTTCCTGGAATTTGTCTCCCT
GTTAGAATCCATTAATACTTCCAAGATGACGGCATCCAGTCAACTGAATGGCTCAGCTGAGCAGAATGAAGAAAGTGGGCTTCTCCGAGA
TAACTGTTCCCAGGAAAAAAAGGAGGAAATCCTGGAAAATGAAAAGCCCAGTGGACACAGTTCTAAGCAAGGAAAACCAGATTTGCAAAG
TCAAGACCATACTAGCACCGGCCCCGCATGCACTCAGCCTGCCAAGACCACAGCCTTTTTTCAGGGCAATAGACAAAGACAGATAATCTA
CAGGGTAACTTCCCAACAAGATAGTTCTGTCTTGCAAGTCATCAGTGGGCCTGAAACATCTGTACAAGAAGAGATATCTGTGGATGCTAT
GCATGTCTTCATTGATGAACATGGGGAAATTAGATCCTGTTATTTAAAATCTGGAAATCAGAAAGAAGGCCCTTTACAGCCTCTACCATC
AAATAATGACTGTCTCTCTCAGGCTCGAGAGATGCAGGTCAGCTCCTCCAGTACCACAACTTCTGAGAGTCAAGATCCGTCTTCTGGGGA
CCCTGCCGTCAGTGCCCTTCAGCAACAGCTGTTACTGATGGTGGCTCGCAGGACCCAGTCGGAAACCCCACGGCATGTGAGTCAGGATCT
GGAAGCCTCGTCATGTTCTTCAACACAAGGAAAATTTAACCGAGAGCAGTTTTACAAATTTATCATTTTCCCTGGCAAGTGGATTAAAGT
CTGGTATGATCGACTGACCTTGCTGGCATTACTTGATCGAACTGAAGACATCAAGGAGAATGTACTGGCGATTTTACTCATTGTCCTGGT
TTCCCTCCTTGGATTTCTGACCTTGAGCCAAGGCTTTTGCAAAGATATGTGGGTGCTCCTCTTCTGCCTCGTCATGGCCAGCTGCCAGTA
CTCCCTGCTAAAGAGTGTTCAGCCTGACCCCGCCTCACCAATACACGGACACAACCAAATCATAACATATAGCAGACCAATCTATTTTTG
TGTGCTGTGTGGCCTTATTTTGCTTCTTGATACAGGGGCCAAAGCCAGGCACCCTCCCAGTTACGTTGTGTATGGCCTGAAGCTCTTCTC
TCCAGTGTTTCTACAATCAGCTAGGGACTACTTAATAGTATTTTTATATTGCTTCCCTGCTATTTCCCTCCTTGGGCTCTTCCCGCAAAT
CAACACTTTCTGCACTTATCTTTTGGAGCAAATTGACATGCTGTTTTTTGGTGGTTCTGCTGTGTCTGGGATAACCTCGGCTGTTTACAG
TGTGGCCCGGAGCGTCTTGGCTGCCGCCCTGCTCCACGCAGTCTGCTTCAGTGCAGTGAAGGAACCGTGGAGCATGCAACACATCCCGGC
ACTGTTTTCGGCCTTCTGTGGCCTCTTGGTCGCCCTTTCTTACCATCTGAGCCGTCAGAGCAGTGACCCATCTGTACTCATGTCCTTCAT
CCAATGCAGGCTGTTTCCTAAATTTTTACATCAAAATCTGGCAGAGTCAGCTGCTGACCCTCTCCCCAAGAAGATGAAAGATTCAGTGAC
GGATGTCTTAAAATGGGATCTCATCGTCTGCGCAGTGGTTGCTGTCCTCTCATTTGCAGTCAGCGCCAGCACTGTATTCCTGTCATTGCG
ACCATTTCTCAGCATCGTGCTGTTTGCCTTGGCTGGAGCCGTGGGGTTTGTAACACATTACGTGCTCCCTCAGCTCCGCAAGCATCATCC
CTGGATGTGGATTTCACACCCCATTCTCAAAAACAAAGAGTATCATCAACGGGAAGTGAGAGATGTTGCCCATTTAATGTGGTTCGAAAG
ACTCTATGTTTGGCTTCAGTGTTTTGAAAAATACATCTTGTACCCAGCGCTAATTTTGAATGCCCTCACTATTGATGCATTTTTAATAAG
CAATCACCGGAGACTTGGTACCCACTGGGACATTTTTCTGATGATCATTGCTGGCATGAAGCTGTTGCGGACATCATTCTGCAACCCGGT
TTACCAGTTTATTAACTTGAGCTTCACTGTCATCTTTTTCCACTTTGACTACAAAGATATTTCAGAGAGCTTCTTACTGGATTTCTTCAT
GGTGTCCATTTTATTTAGCAAGCATGACTTTGTTCGACGAGACCGGCCACTACGTGTCCTCATTGACCTCATACAGAGGACAAAAGATGC
AGTTCGTGAGCTAGATAACCTACAGTACCGAAAAATGAAAAAAATACTTTTCCAAGAGACACGGAATGGACCCTTGAATGAGTCACAGGA
GGATGAGGAAGACAGTGAACATGGAACCAGCCTGAACAGGGAAATGGACAGCCTGGGCAGCAACCATTCCATTCCAAGCATGTCCGTGAG
CACAGGCAGCCAGAGCAGCAGTGTGAACAGCATGCAGGAAGTCATGGACGAGAGCAGTTCCGAACTTGTCATGATGCACGATGACGAAAG
CACAATCAATTCCAGCTCCTCCGTCGTGCATAAGAAAGATCATGTATTCATAAGGGATGAGGCGGGCCACGGCGATCCCAGGCCTGAGCC
GCGGCCTACCCAGTCAGTTCAGAGCCAGGCCCTCCACTACCGGAACAGAGAGCGCTTTGCCACGATCAAATCAGCATCTTTGGTTACACG
ACAGATCCATGAGCATGAGCAGGAGAACGAGTTGCGGGAACAGATGTCAGGTTATAAGCGGATGCGGCGCCAGCACCAGAAGCAGCTGAT
CGCCCTGGAGAACAAGCTGAAGGCTGAGATGGACGAGCACCGCCTCAAGCTACAGAAGGAGGTGGAGACGCATGCCAACAACTCGTCCAT
CGAGCTGGAGAAGCTGGCCAAGAAGCAAGTGGCTATCATAGAAAAGGAGGCAAAGGTAGCTGCAGCAGATGAGAAGAAGTTCCAGCAACA
GATCTTGGCCCAGCAGAAGAAAGATTTGACAACTTTCTTAGAAAGTCAGAAGAAGCAGTATAAGATTTGTAAGGAAAAAATAAAAGAGGA
AATGAATGAGGACCATAGCACACCCAAGAAAGAGAAGCAAGAGCGGATCTCCAAACATAAAGAGAACTTGCAGCACACACAGGCTGAAGA
GGAAGCCCACCTTCTCACTCAACAGAGACTGTACTACGACAAAAATTGTCGTTTCTTCAAGCGGAAAATAATGATCAAGCGGCACGAGGT
GGAGCAGCAGAACATTCGGGAGGAACTAAATAAAAAGAGGACCCAGAAGGAGATGGAGCATGCCATGCTAATCCGGCACGACGAGTCCAC
CCGAGAGCTAGAGTACAGGCAGCTGCACACGTTACAGAAGCTACGCATGGATCTGATCCGTTTACAGCACCAGACGGAACTGGAAAACCA
GCTGGAGTACAATAAGAGGCGAGAAAGAGAACTGCACAGAAAGCATGTCATGGAACTTCGGCAACAGCCAAAAAACTTAAAGGCCATGGA
AATGCAAATTAAAAAACAGTTTCAGGACACTTGCAAAGTACAGACCAAACAGTATAAAGCACTCAAGAATCACCAGTTGGAAGTTACTCC
AAAGAATGAGCACAAAACAATCTTAAAGACACTGAAAGATGAGCAGACAAGAAAACTTGCCATTTTGGCAGAGCAGTATGAACAGAGTAT
AAATGAAATGATGGCCTCTCAAGCGTTACGGCTAGATGAGGCTCAAGAAGCAGAATGCCAGGCCTTGAGGCTACAGCTCCAGCAGGAAAT
GGAGCTGCTCAACGCCTACCAGAGCAAAATCAAGATGCAAACAGAGGCACAACATGAACGTGAGCTCCAGAAGCTAGAGCAGAGAGTGTC
TCTGCGCAGAGCACACCTTGAGCAGAAGATTGAAGAGGAGCTGGCTGCCCTTCAGAAGGAACGCAGCGAGAGAATAAAGAACCTATTGGA
AAGGCAAGAGCGAGAGATTGAAACTTTTGACATGGAGAGCCTCAGAATGGGATTTGGGAATTTGGTTACATTAGATTTTCCTAAGGAGGA
CTACAGATGAGATTAAATTTTTTGCCATTTACAAAAAAAAAAAAAAAAAAGAAAACAGAAAAAAATTCAGACCCTGCAAAACCACATTCC
CCATTTTAACGGGCGTTGCTCTCACTCTCTCTCTCTCTTACTCTTACTGACATCGTGTCGGACTAGTGCCTGTTTATTCTTACTCCATCA
GGGGCCCCCTTCCTCCCCCCGTGTCAACTTTCAGTGCTGGCCAAAACCTGGCCGTCTCTTCTATTCACAGTACACGTCACAGTATTGATG
TGATTCAAAATGTTTCAGTGAAAACTTTGGAGACAGTTTTAACAAAACCAATAAACCAACAACAAAAAAAGTGGATGTATATTGCTTTAA
GCAATCACTCATTACCACCAATCTGTGAAAGTAAAGCAAAAAATAATAATAATAAATGCCAAGGGGGAGAGAGACACAATATCCGCAGCC
TTACACCTTAACTAGCTGCTGCATTATTTTATTTTATTTTATTTTTTTGGTATTTATTCATCAGGAATAAAAAAAACAAAGTTTTATTAA
AGATTGAAAATTTGATACATTTTACAGAAACTAATTGTGATGTACATATCAGTGGTGACATATTATTACTTTTTTGGGGACGGGGGGTGG
GTGGGGTGAAGAGATCTTGTGATTTTTAAGAACCTGCTGGCAAGAGTTTAACTTGTCTTCAGCATATTCTGATTGTATCATAATCATTTT
CTGCTGTTGCAGAGGATGTGAATACACTTAAGGAGCTCACAGAATCCCAGTAGCACAAATTGGGCTTTGGCAAATCGTGTATTTTGTGTA
TAGAAGGAATTTAAGGAGAGGTATTACTTATTTTCATATTGTATTTTAACTGTTTCTCTGATCAAATTTTTTTACTTCCTCCTCCTGTTC
CTCCCCACCTCCCTCCTTTTCCAGTTCAGTATTTGGAGTTCAACACTGTCTCTCAATCAGATCATCTTGATCTTTTTCTTTATCTCCCTT
CCCCTTCCTAAGTCCCATTTCTTGGTCATAAATATTGCATTATTCACACTTTCAAACTGTGTATTTTCTTACAATAAAAAATGATGAAAA
AAAAAAAGGCTTTACTTCTTTTGCATGCACTTTAAAAACAAAACAAAACATTTTTCAGGTTCCAAGGAAGAGCATGATAACTGTCAGAGC

>63465_63465_1_PCNXL2-TAOK3_PCNXL2_chr1_233270759_ENST00000258229_TAOK3_chr12_118639268_ENST00000392533_length(amino acids)=1979AA_BP=1354
MPGRSSRLRRRGSRVRAEEQLQLQTWGGRRRRGRRRRRRRGRGPRARVLDLREPGDPAGARRVQRGAHQPRGAAGMVSQVLQLLRQGVWA
ALTGGWYHDPEQSKFTNSCHLYLWLFLLLLPLALHLAFPPNAIIVFFYCSAVTIFFTIIKLVSYRLHLMFDKGEVIQQKPSRKEEKPNKD
KEAKGEHITNHRNPSNNRQIHNGKKEEASRNLSTPPLRCSSRGQSITSHHSSGPLELSAQETVEDLKGVILLEDHPIAPVSSTSPGIKVE
SLPASQAHMLETTTKSVIPVKPVATETLINGKGKERGGKGQPPLRHRSEGGLVDKGPLKKLPHLSLSQYDLLETDVSFQPWGSENSVLIP
EPVSCPRGSIRERVQSKSPQDSLSSSCPQCDTIVAKPVEEPADTSCQVDTSCQGDLPLHQEVDSSDSEVAVTLIDTSQPGDPLSLHEPIK
IVITMSSTPNSMTDLESSLHLRVVGTEKTSVKSDAEPTNPGAAGSPNAEQISIPVITLDLPEGGGGGVPCPEGNGSERTPERLKTRVSTN
QCSGYGSGEGGNAIKDHSSSSREPWESVSRLTPDTGSESKVGKEGQTNLDPSSCKSSHEKRHARVLSVDSGTDVFLSKSSAEIVNDTEKT
MPTSKSDLEAKEGQMPNESNFLEFVSLLESINTSKMTASSQLNGSAEQNEESGLLRDNCSQEKKEEILENEKPSGHSSKQGKPDLQSQDH
TSTGPACTQPAKTTAFFQGNRQRQIIYRVTSQQDSSVLQVISGPETSVQEEISVDAMHVFIDEHGEIRSCYLKSGNQKEGPLQPLPSNND
CLSQAREMQVSSSSTTTSESQDPSSGDPAVSALQQQLLLMVARRTQSETPRHVSQDLEASSCSSTQGKFNREQFYKFIIFPGKWIKVWYD
RLTLLALLDRTEDIKENVLAILLIVLVSLLGFLTLSQGFCKDMWVLLFCLVMASCQYSLLKSVQPDPASPIHGHNQIITYSRPIYFCVLC
GLILLLDTGAKARHPPSYVVYGLKLFSPVFLQSARDYLIVFLYCFPAISLLGLFPQINTFCTYLLEQIDMLFFGGSAVSGITSAVYSVAR
SVLAAALLHAVCFSAVKEPWSMQHIPALFSAFCGLLVALSYHLSRQSSDPSVLMSFIQCRLFPKFLHQNLAESAADPLPKKMKDSVTDVL
KWDLIVCAVVAVLSFAVSASTVFLSLRPFLSIVLFALAGAVGFVTHYVLPQLRKHHPWMWISHPILKNKEYHQREVRDVAHLMWFERLYV
WLQCFEKYILYPALILNALTIDAFLISNHRRLGTHWDIFLMIIAGMKLLRTSFCNPVYQFINLSFTVIFFHFDYKDISESFLLDFFMVSI
LFSKHDFVRRDRPLRVLIDLIQRTKDAVRELDNLQYRKMKKILFQETRNGPLNESQEDEEDSEHGTSLNREMDSLGSNHSIPSMSVSTGS
QSSSVNSMQEVMDESSSELVMMHDDESTINSSSSVVHKKDHVFIRDEAGHGDPRPEPRPTQSVQSQALHYRNRERFATIKSASLVTRQIH
EHEQENELREQMSGYKRMRRQHQKQLIALENKLKAEMDEHRLKLQKEVETHANNSSIELEKLAKKQVAIIEKEAKVAAADEKKFQQQILA
QQKKDLTTFLESQKKQYKICKEKIKEEMNEDHSTPKKEKQERISKHKENLQHTQAEEEAHLLTQQRLYYDKNCRFFKRKIMIKRHEVEQQ
NIREELNKKRTQKEMEHAMLIRHDESTRELEYRQLHTLQKLRMDLIRLQHQTELENQLEYNKRRERELHRKHVMELRQQPKNLKAMEMQI
KKQFQDTCKVQTKQYKALKNHQLEVTPKNEHKTILKTLKDEQTRKLAILAEQYEQSINEMMASQALRLDEAQEAECQALRLQLQQEMELL

--------------------------------------------------------------
>63465_63465_2_PCNXL2-TAOK3_PCNXL2_chr1_233270759_ENST00000258229_TAOK3_chr12_118639268_ENST00000419821_length(transcript)=7146nt_BP=4072nt
TGGCGCTCACCTGCCCGGCCGCAGCAGCCGGCTCCGGCGCCGCGGTTCGCGGGTCCGGGCGGAAGAGCAGCTCCAGCTTCAAACGTGGGG
TGGAAGGAGGCGGCGGGGGCGACGGCGGCGGCGACGGCGGGGGCGCGGCCCGCGGGCCCGGGTGTTAGACCTGAGGGAGCCTGGAGATCC
GGCCGGGGCGCGCAGGGTGCAGCGGGGCGCTCACCAGCCCCGGGGCGCAGCCGGCATGGTGTCCCAGGTGCTGCAGCTGCTCCGGCAGGG
CGTGTGGGCCGCGCTCACCGGGGGCTGGTACCACGACCCGGAGCAGAGCAAGTTCACCAACAGCTGCCACCTCTACCTGTGGCTGTTCCT
CCTGCTGCTGCCCCTGGCCCTGCACCTGGCTTTTCCTCCAAATGCGATCATTGTATTTTTCTACTGCAGTGCAGTGACTATATTCTTCAC
AATAATCAAACTGGTCAGTTATCGCCTACACCTCATGTTTGACAAAGGAGAAGTAATTCAGCAAAAGCCCTCCAGAAAGGAAGAAAAGCC
AAATAAAGACAAGGAGGCCAAAGGTGAACACATAACTAATCACAGAAATCCAAGCAATAATAGGCAGATTCACAATGGCAAAAAGGAAGA
GGCCAGTCGAAACCTCTCCACGCCTCCCCTCCGCTGCAGCTCCAGAGGGCAAAGCATAACCTCTCATCACTCTTCTGGGCCATTGGAGTT
GTCAGCACAGGAAACTGTAGAAGATCTCAAAGGTGTCATTCTATTAGAAGACCATCCCATAGCACCAGTGTCATCTACCTCACCTGGTAT
CAAAGTGGAAAGCTTACCTGCGTCTCAAGCACACATGCTGGAAACCACGACCAAGTCAGTAATACCTGTAAAACCAGTTGCCACAGAAAC
TCTCATCAATGGTAAAGGAAAGGAAAGAGGAGGCAAGGGGCAGCCTCCTTTGCGCCACAGATCCGAGGGTGGCTTAGTGGATAAGGGACC
CTTGAAGAAGTTGCCCCACCTGTCTTTGTCTCAGTATGACTTACTAGAAACAGACGTTTCTTTCCAGCCGTGGGGGAGTGAGAATTCAGT
CCTGATTCCAGAACCTGTCAGTTGTCCCCGGGGCTCCATAAGGGAACGGGTACAAAGCAAGTCACCTCAGGACAGCCTGAGCAGCAGCTG
CCCTCAATGTGACACCATCGTGGCCAAGCCTGTGGAGGAGCCAGCAGACACATCCTGTCAGGTAGATACCTCCTGCCAGGGGGACCTGCC
CTTGCACCAGGAAGTGGACTCCTCAGATAGTGAGGTAGCTGTTACTCTCATCGATACTTCTCAACCCGGAGACCCACTGAGTCTACATGA
GCCCATAAAAATTGTTATCACGATGAGCAGTACCCCAAACTCCATGACAGATTTGGAAAGCTCCCTCCACCTGAGGGTGGTTGGCACAGA
GAAGACCAGTGTAAAGTCTGACGCTGAGCCCACTAACCCAGGGGCGGCCGGTTCTCCAAATGCCGAGCAGATCTCAATTCCTGTAATCAC
CCTGGACCTGCCTGAGGGTGGGGGAGGAGGTGTTCCCTGTCCCGAAGGCAATGGAAGTGAAAGGACTCCAGAGAGACTGAAGACGAGGGT
ATCCACCAATCAGTGTTCTGGCTACGGATCTGGGGAGGGGGGAAATGCCATCAAGGATCACAGTTCTTCATCACGGGAACCCTGGGAATC
GGTGTCCCGGCTTACACCTGATACAGGCTCCGAGTCTAAGGTGGGGAAGGAAGGCCAGACTAACCTTGACCCATCGTCTTGTAAGTCCAG
CCATGAAAAGAGGCATGCCCGGGTGCTCAGTGTGGACAGTGGGACAGATGTCTTCTTGAGTAAAAGTTCTGCAGAAATTGTTAACGATAC
AGAGAAAACAATGCCAACTTCCAAATCTGACCTAGAGGCTAAGGAAGGACAAATGCCAAATGAGTCCAACTTCCTGGAATTTGTCTCCCT
GTTAGAATCCATTAATACTTCCAAGATGACGGCATCCAGTCAACTGAATGGCTCAGCTGAGCAGAATGAAGAAAGTGGGCTTCTCCGAGA
TAACTGTTCCCAGGAAAAAAAGGAGGAAATCCTGGAAAATGAAAAGCCCAGTGGACACAGTTCTAAGCAAGGAAAACCAGATTTGCAAAG
TCAAGACCATACTAGCACCGGCCCCGCATGCACTCAGCCTGCCAAGACCACAGCCTTTTTTCAGGGCAATAGACAAAGACAGATAATCTA
CAGGGTAACTTCCCAACAAGATAGTTCTGTCTTGCAAGTCATCAGTGGGCCTGAAACATCTGTACAAGAAGAGATATCTGTGGATGCTAT
GCATGTCTTCATTGATGAACATGGGGAAATTAGATCCTGTTATTTAAAATCTGGAAATCAGAAAGAAGGCCCTTTACAGCCTCTACCATC
AAATAATGACTGTCTCTCTCAGGCTCGAGAGATGCAGGTCAGCTCCTCCAGTACCACAACTTCTGAGAGTCAAGATCCGTCTTCTGGGGA
CCCTGCCGTCAGTGCCCTTCAGCAACAGCTGTTACTGATGGTGGCTCGCAGGACCCAGTCGGAAACCCCACGGCATGTGAGTCAGGATCT
GGAAGCCTCGTCATGTTCTTCAACACAAGGAAAATTTAACCGAGAGCAGTTTTACAAATTTATCATTTTCCCTGGCAAGTGGATTAAAGT
CTGGTATGATCGACTGACCTTGCTGGCATTACTTGATCGAACTGAAGACATCAAGGAGAATGTACTGGCGATTTTACTCATTGTCCTGGT
TTCCCTCCTTGGATTTCTGACCTTGAGCCAAGGCTTTTGCAAAGATATGTGGGTGCTCCTCTTCTGCCTCGTCATGGCCAGCTGCCAGTA
CTCCCTGCTAAAGAGTGTTCAGCCTGACCCCGCCTCACCAATACACGGACACAACCAAATCATAACATATAGCAGACCAATCTATTTTTG
TGTGCTGTGTGGCCTTATTTTGCTTCTTGATACAGGGGCCAAAGCCAGGCACCCTCCCAGTTACGTTGTGTATGGCCTGAAGCTCTTCTC
TCCAGTGTTTCTACAATCAGCTAGGGACTACTTAATAGTATTTTTATATTGCTTCCCTGCTATTTCCCTCCTTGGGCTCTTCCCGCAAAT
CAACACTTTCTGCACTTATCTTTTGGAGCAAATTGACATGCTGTTTTTTGGTGGTTCTGCTGTGTCTGGGATAACCTCGGCTGTTTACAG
TGTGGCCCGGAGCGTCTTGGCTGCCGCCCTGCTCCACGCAGTCTGCTTCAGTGCAGTGAAGGAACCGTGGAGCATGCAACACATCCCGGC
ACTGTTTTCGGCCTTCTGTGGCCTCTTGGTCGCCCTTTCTTACCATCTGAGCCGTCAGAGCAGTGACCCATCTGTACTCATGTCCTTCAT
CCAATGCAGGCTGTTTCCTAAATTTTTACATCAAAATCTGGCAGAGTCAGCTGCTGACCCTCTCCCCAAGAAGATGAAAGATTCAGTGAC
GGATGTCTTAAAATGGGATCTCATCGTCTGCGCAGTGGTTGCTGTCCTCTCATTTGCAGTCAGCGCCAGCACTGTATTCCTGTCATTGCG
ACCATTTCTCAGCATCGTGCTGTTTGCCTTGGCTGGAGCCGTGGGGTTTGTAACACATTACGTGCTCCCTCAGCTCCGCAAGCATCATCC
CTGGATGTGGATTTCACACCCCATTCTCAAAAACAAAGAGTATCATCAACGGGAAGTGAGAGATGTTGCCCATTTAATGTGGTTCGAAAG
ACTCTATGTTTGGCTTCAGTGTTTTGAAAAATACATCTTGTACCCAGCGCTAATTTTGAATGCCCTCACTATTGATGCATTTTTAATAAG
CAATCACCGGAGACTTGGTACCCACTGGGACATTTTTCTGATGATCATTGCTGGCATGAAGCTGTTGCGGACATCATTCTGCAACCCGGT
TTACCAGTTTATTAACTTGAGCTTCACTGTCATCTTTTTCCACTTTGACTACAAAGATATTTCAGAGAGCTTCTTACTGGATTTCTTCAT
GGTGTCCATTTTATTTAGCAAGCATGACTTTGTTCGACGAGACCGGCCACTACGTGTCCTCATTGACCTCATACAGAGGACAAAAGATGC
AGTTCGTGAGCTAGATAACCTACAGTACCGAAAAATGAAAAAAATACTTTTCCAAGAGACACGGAATGGACCCTTGAATGAGTCACAGGA
GGATGAGGAAGACAGTGAACATGGAACCAGCCTGAACAGGGAAATGGACAGCCTGGGCAGCAACCATTCCATTCCAAGCATGTCCGTGAG
CACAGGCAGCCAGAGCAGCAGTGTGAACAGCATGCAGGAAGTCATGGACGAGAGCAGTTCCGAACTTGTCATGATGCACGATGACGAAAG
CACAATCAATTCCAGCTCCTCCGTCGTGCATAAGAAAGATCATGTATTCATAAGGGATGAGGCGGGCCACGGCGATCCCAGGCCTGAGCC
GCGGCCTACCCAGTCAGTTCAGAGCCAGGCCCTCCACTACCGGAACAGAGAGCGCTTTGCCACGATCAAATCAGCATCTTTGGTTACACG
ACAGATCCATGAGCATGAGCAGGAGAACGAGTTGCGGGAACAGATGTCAGGTTATAAGCGGATGCGGCGCCAGCACCAGAAGCAGCTGAT
CGCCCTGGAGAACAAGCTGAAGGCTGAGATGGACGAGCACCGCCTCAAGCTACAGAAGGAGGTGGAGACGCATGCCAACAACTCGTCCAT
CGAGCTGGAGAAGCTGGCCAAGAAGCAAGTGGCTATCATAGAAAAGGAGGCAAAGGTAGCTGCAGCAGATGAGAAGAAGTTCCAGCAACA
GATCTTGGCCCAGCAGAAGAAAGATTTGACAACTTTCTTAGAAAGTCAGAAGAAGCAGTATAAGATTTGTAAGGAAAAAATAAAAGAGGA
AATGAATGAGGACCATAGCACACCCAAGAAAGAGAAGCAAGAGCGGATCTCCAAACATAAAGAGAACTTGCAGCACACACAGGCTGAAGA
GGAAGCCCACCTTCTCACTCAACAGAGACTGTACTACGACAAAAATTGTCGTTTCTTCAAGCGGAAAATAATGATCAAGCGGCACGAGGT
GGAGCAGCAGAACATTCGGGAGGAACTAAATAAAAAGAGGACCCAGAAGGAGATGGAGCATGCCATGCTAATCCGGCACGACGAGTCCAC
CCGAGAGCTAGAGTACAGGCAGCTGCACACGTTACAGAAGCTACGCATGGATCTGATCCGTTTACAGCACCAGACGGAACTGGAAAACCA
GCTGGAGTACAATAAGAGGCGAGAAAGAGAACTGCACAGAAAGCATGTCATGGAACTTCGGCAACAGCCAAAAAACTTAAAGGCCATGGA
AATGCAAATTAAAAAACAGTTTCAGGACACTTGCAAAGTACAGACCAAACAGTATAAAGCACTCAAGAATCACCAGTTGGAAGTTACTCC
AAAGAATGAGCACAAAACAATCTTAAAGACACTGAAAGATGAGCAGACAAGAAAACTTGCCATTTTGGCAGAGCAGTATGAACAGAGTAT
AAATGAAATGATGGCCTCTCAAGCGTTACGGCTAGATGAGGCTCAAGAAGCAGAATGCCAGGCCTTGAGGCTACAGCTCCAGCAGGAAAT
GGAGCTGCTCAACGCCTACCAGAGCAAAATCAAGATGCAAACAGAGGCACAACATGAACGTGAGCTCCAGAAGCTAGAGCAGAGAGTGTC
TCTGCGCAGAGCACACCTTGAGCAGAAGATTGAAGAGGAGCTGGCTGCCCTTCAGAAGGAACGCAGCGAGAGAATAAAGAACCTATTGGA
AAGGCAAGAGCGAGAGATTGAAACTTTTGACATGGAGAGCCTCAGAATGGGATTTGGGAATTTGGTTACATTAGATTTTCCTAAGGAGGA
CTACAGATGAGATTAAATTTTTTGCCATTTACAAAAAAAAAAAAAAAAAAGAAAACAGAAAAAAATTCAGACCCTGCAAAACCACATTCC
CCATTTTAACGGGCGTTGCTCTCACTCTCTCTCTCTCTTACTCTTACTGACATCGTGTCGGACTAGTGCCTGTTTATTCTTACTCCATCA
GGGGCCCCCTTCCTCCCCCCGTGTCAACTTTCAGTGCTGGCCAAAACCTGGCCGTCTCTTCTATTCACAGTACACGTCACAGTATTGATG
TGATTCAAAATGTTTCAGTGAAAACTTTGGAGACAGTTTTAACAAAACCAATAAACCAACAACAAAAAAAGTGGATGTATATTGCTTTAA
GCAATCACTCATTACCACCAATCTGTGAAAGTAAAGCAAAAAATAATAATAATAAATGCCAAGGGGGAGAGAGACACAATATCCGCAGCC
TTACACCTTAACTAGCTGCTGCATTATTTTATTTTATTTTATTTTTTTGGTATTTATTCATCAGGAATAAAAAAAACAAAGTTTTATTAA
AGATTGAAAATTTGATACATTTTACAGAAACTAATTGTGATGTACATATCAGTGGTGACATATTATTACTTTTTTGGGGACGGGGGGTGG
GTGGGGTGAAGAGATCTTGTGATTTTTAAGAACCTGCTGGCAAGAGTTTAACTTGTCTTCAGCATATTCTGATTGTATCATAATCATTTT
CTGCTGTTGCAGAGGATGTGAATACACTTAAGGAGCTCACAGAATCCCAGTAGCACAAATTGGGCTTTGGCAAATCGTGTATTTTGTGTA
TAGAAGGAATTTAAGGAGAGGTATTACTTATTTTCATATTGTATTTTAACTGTTTCTCTGATCAAATTTTTTTACTTCCTCCTCCTGTTC
CTCCCCACCTCCCTCCTTTTCCAGTTCAGTATTTGGAGTTCAACACTGTCTCTCAATCAGATCATCTTGATCTTTTTCTTTATCTCCCTT
CCCCTTCCTAAGTCCCATTTCTTGGTCATAAATATTGCATTATTCACACTTTCAAACTGTGTATTTTCTTACAATAAAAAATGATGAAAA
AAAAAAAGGCTTTACTTCTTTTGCATGCACTTTAAAAACAAAACAAAACATTTTTCAGGTTCCAAGGAAGAGCATGATAACTGTCAGAGC

>63465_63465_2_PCNXL2-TAOK3_PCNXL2_chr1_233270759_ENST00000258229_TAOK3_chr12_118639268_ENST00000419821_length(amino acids)=1979AA_BP=1354
MPGRSSRLRRRGSRVRAEEQLQLQTWGGRRRRGRRRRRRRGRGPRARVLDLREPGDPAGARRVQRGAHQPRGAAGMVSQVLQLLRQGVWA
ALTGGWYHDPEQSKFTNSCHLYLWLFLLLLPLALHLAFPPNAIIVFFYCSAVTIFFTIIKLVSYRLHLMFDKGEVIQQKPSRKEEKPNKD
KEAKGEHITNHRNPSNNRQIHNGKKEEASRNLSTPPLRCSSRGQSITSHHSSGPLELSAQETVEDLKGVILLEDHPIAPVSSTSPGIKVE
SLPASQAHMLETTTKSVIPVKPVATETLINGKGKERGGKGQPPLRHRSEGGLVDKGPLKKLPHLSLSQYDLLETDVSFQPWGSENSVLIP
EPVSCPRGSIRERVQSKSPQDSLSSSCPQCDTIVAKPVEEPADTSCQVDTSCQGDLPLHQEVDSSDSEVAVTLIDTSQPGDPLSLHEPIK
IVITMSSTPNSMTDLESSLHLRVVGTEKTSVKSDAEPTNPGAAGSPNAEQISIPVITLDLPEGGGGGVPCPEGNGSERTPERLKTRVSTN
QCSGYGSGEGGNAIKDHSSSSREPWESVSRLTPDTGSESKVGKEGQTNLDPSSCKSSHEKRHARVLSVDSGTDVFLSKSSAEIVNDTEKT
MPTSKSDLEAKEGQMPNESNFLEFVSLLESINTSKMTASSQLNGSAEQNEESGLLRDNCSQEKKEEILENEKPSGHSSKQGKPDLQSQDH
TSTGPACTQPAKTTAFFQGNRQRQIIYRVTSQQDSSVLQVISGPETSVQEEISVDAMHVFIDEHGEIRSCYLKSGNQKEGPLQPLPSNND
CLSQAREMQVSSSSTTTSESQDPSSGDPAVSALQQQLLLMVARRTQSETPRHVSQDLEASSCSSTQGKFNREQFYKFIIFPGKWIKVWYD
RLTLLALLDRTEDIKENVLAILLIVLVSLLGFLTLSQGFCKDMWVLLFCLVMASCQYSLLKSVQPDPASPIHGHNQIITYSRPIYFCVLC
GLILLLDTGAKARHPPSYVVYGLKLFSPVFLQSARDYLIVFLYCFPAISLLGLFPQINTFCTYLLEQIDMLFFGGSAVSGITSAVYSVAR
SVLAAALLHAVCFSAVKEPWSMQHIPALFSAFCGLLVALSYHLSRQSSDPSVLMSFIQCRLFPKFLHQNLAESAADPLPKKMKDSVTDVL
KWDLIVCAVVAVLSFAVSASTVFLSLRPFLSIVLFALAGAVGFVTHYVLPQLRKHHPWMWISHPILKNKEYHQREVRDVAHLMWFERLYV
WLQCFEKYILYPALILNALTIDAFLISNHRRLGTHWDIFLMIIAGMKLLRTSFCNPVYQFINLSFTVIFFHFDYKDISESFLLDFFMVSI
LFSKHDFVRRDRPLRVLIDLIQRTKDAVRELDNLQYRKMKKILFQETRNGPLNESQEDEEDSEHGTSLNREMDSLGSNHSIPSMSVSTGS
QSSSVNSMQEVMDESSSELVMMHDDESTINSSSSVVHKKDHVFIRDEAGHGDPRPEPRPTQSVQSQALHYRNRERFATIKSASLVTRQIH
EHEQENELREQMSGYKRMRRQHQKQLIALENKLKAEMDEHRLKLQKEVETHANNSSIELEKLAKKQVAIIEKEAKVAAADEKKFQQQILA
QQKKDLTTFLESQKKQYKICKEKIKEEMNEDHSTPKKEKQERISKHKENLQHTQAEEEAHLLTQQRLYYDKNCRFFKRKIMIKRHEVEQQ
NIREELNKKRTQKEMEHAMLIRHDESTRELEYRQLHTLQKLRMDLIRLQHQTELENQLEYNKRRERELHRKHVMELRQQPKNLKAMEMQI
KKQFQDTCKVQTKQYKALKNHQLEVTPKNEHKTILKTLKDEQTRKLAILAEQYEQSINEMMASQALRLDEAQEAECQALRLQLQQEMELL

--------------------------------------------------------------
>63465_63465_3_PCNXL2-TAOK3_PCNXL2_chr1_233270761_ENST00000258229_TAOK3_chr12_118639270_ENST00000392533_length(transcript)=7146nt_BP=4072nt
TGGCGCTCACCTGCCCGGCCGCAGCAGCCGGCTCCGGCGCCGCGGTTCGCGGGTCCGGGCGGAAGAGCAGCTCCAGCTTCAAACGTGGGG
TGGAAGGAGGCGGCGGGGGCGACGGCGGCGGCGACGGCGGGGGCGCGGCCCGCGGGCCCGGGTGTTAGACCTGAGGGAGCCTGGAGATCC
GGCCGGGGCGCGCAGGGTGCAGCGGGGCGCTCACCAGCCCCGGGGCGCAGCCGGCATGGTGTCCCAGGTGCTGCAGCTGCTCCGGCAGGG
CGTGTGGGCCGCGCTCACCGGGGGCTGGTACCACGACCCGGAGCAGAGCAAGTTCACCAACAGCTGCCACCTCTACCTGTGGCTGTTCCT
CCTGCTGCTGCCCCTGGCCCTGCACCTGGCTTTTCCTCCAAATGCGATCATTGTATTTTTCTACTGCAGTGCAGTGACTATATTCTTCAC
AATAATCAAACTGGTCAGTTATCGCCTACACCTCATGTTTGACAAAGGAGAAGTAATTCAGCAAAAGCCCTCCAGAAAGGAAGAAAAGCC
AAATAAAGACAAGGAGGCCAAAGGTGAACACATAACTAATCACAGAAATCCAAGCAATAATAGGCAGATTCACAATGGCAAAAAGGAAGA
GGCCAGTCGAAACCTCTCCACGCCTCCCCTCCGCTGCAGCTCCAGAGGGCAAAGCATAACCTCTCATCACTCTTCTGGGCCATTGGAGTT
GTCAGCACAGGAAACTGTAGAAGATCTCAAAGGTGTCATTCTATTAGAAGACCATCCCATAGCACCAGTGTCATCTACCTCACCTGGTAT
CAAAGTGGAAAGCTTACCTGCGTCTCAAGCACACATGCTGGAAACCACGACCAAGTCAGTAATACCTGTAAAACCAGTTGCCACAGAAAC
TCTCATCAATGGTAAAGGAAAGGAAAGAGGAGGCAAGGGGCAGCCTCCTTTGCGCCACAGATCCGAGGGTGGCTTAGTGGATAAGGGACC
CTTGAAGAAGTTGCCCCACCTGTCTTTGTCTCAGTATGACTTACTAGAAACAGACGTTTCTTTCCAGCCGTGGGGGAGTGAGAATTCAGT
CCTGATTCCAGAACCTGTCAGTTGTCCCCGGGGCTCCATAAGGGAACGGGTACAAAGCAAGTCACCTCAGGACAGCCTGAGCAGCAGCTG
CCCTCAATGTGACACCATCGTGGCCAAGCCTGTGGAGGAGCCAGCAGACACATCCTGTCAGGTAGATACCTCCTGCCAGGGGGACCTGCC
CTTGCACCAGGAAGTGGACTCCTCAGATAGTGAGGTAGCTGTTACTCTCATCGATACTTCTCAACCCGGAGACCCACTGAGTCTACATGA
GCCCATAAAAATTGTTATCACGATGAGCAGTACCCCAAACTCCATGACAGATTTGGAAAGCTCCCTCCACCTGAGGGTGGTTGGCACAGA
GAAGACCAGTGTAAAGTCTGACGCTGAGCCCACTAACCCAGGGGCGGCCGGTTCTCCAAATGCCGAGCAGATCTCAATTCCTGTAATCAC
CCTGGACCTGCCTGAGGGTGGGGGAGGAGGTGTTCCCTGTCCCGAAGGCAATGGAAGTGAAAGGACTCCAGAGAGACTGAAGACGAGGGT
ATCCACCAATCAGTGTTCTGGCTACGGATCTGGGGAGGGGGGAAATGCCATCAAGGATCACAGTTCTTCATCACGGGAACCCTGGGAATC
GGTGTCCCGGCTTACACCTGATACAGGCTCCGAGTCTAAGGTGGGGAAGGAAGGCCAGACTAACCTTGACCCATCGTCTTGTAAGTCCAG
CCATGAAAAGAGGCATGCCCGGGTGCTCAGTGTGGACAGTGGGACAGATGTCTTCTTGAGTAAAAGTTCTGCAGAAATTGTTAACGATAC
AGAGAAAACAATGCCAACTTCCAAATCTGACCTAGAGGCTAAGGAAGGACAAATGCCAAATGAGTCCAACTTCCTGGAATTTGTCTCCCT
GTTAGAATCCATTAATACTTCCAAGATGACGGCATCCAGTCAACTGAATGGCTCAGCTGAGCAGAATGAAGAAAGTGGGCTTCTCCGAGA
TAACTGTTCCCAGGAAAAAAAGGAGGAAATCCTGGAAAATGAAAAGCCCAGTGGACACAGTTCTAAGCAAGGAAAACCAGATTTGCAAAG
TCAAGACCATACTAGCACCGGCCCCGCATGCACTCAGCCTGCCAAGACCACAGCCTTTTTTCAGGGCAATAGACAAAGACAGATAATCTA
CAGGGTAACTTCCCAACAAGATAGTTCTGTCTTGCAAGTCATCAGTGGGCCTGAAACATCTGTACAAGAAGAGATATCTGTGGATGCTAT
GCATGTCTTCATTGATGAACATGGGGAAATTAGATCCTGTTATTTAAAATCTGGAAATCAGAAAGAAGGCCCTTTACAGCCTCTACCATC
AAATAATGACTGTCTCTCTCAGGCTCGAGAGATGCAGGTCAGCTCCTCCAGTACCACAACTTCTGAGAGTCAAGATCCGTCTTCTGGGGA
CCCTGCCGTCAGTGCCCTTCAGCAACAGCTGTTACTGATGGTGGCTCGCAGGACCCAGTCGGAAACCCCACGGCATGTGAGTCAGGATCT
GGAAGCCTCGTCATGTTCTTCAACACAAGGAAAATTTAACCGAGAGCAGTTTTACAAATTTATCATTTTCCCTGGCAAGTGGATTAAAGT
CTGGTATGATCGACTGACCTTGCTGGCATTACTTGATCGAACTGAAGACATCAAGGAGAATGTACTGGCGATTTTACTCATTGTCCTGGT
TTCCCTCCTTGGATTTCTGACCTTGAGCCAAGGCTTTTGCAAAGATATGTGGGTGCTCCTCTTCTGCCTCGTCATGGCCAGCTGCCAGTA
CTCCCTGCTAAAGAGTGTTCAGCCTGACCCCGCCTCACCAATACACGGACACAACCAAATCATAACATATAGCAGACCAATCTATTTTTG
TGTGCTGTGTGGCCTTATTTTGCTTCTTGATACAGGGGCCAAAGCCAGGCACCCTCCCAGTTACGTTGTGTATGGCCTGAAGCTCTTCTC
TCCAGTGTTTCTACAATCAGCTAGGGACTACTTAATAGTATTTTTATATTGCTTCCCTGCTATTTCCCTCCTTGGGCTCTTCCCGCAAAT
CAACACTTTCTGCACTTATCTTTTGGAGCAAATTGACATGCTGTTTTTTGGTGGTTCTGCTGTGTCTGGGATAACCTCGGCTGTTTACAG
TGTGGCCCGGAGCGTCTTGGCTGCCGCCCTGCTCCACGCAGTCTGCTTCAGTGCAGTGAAGGAACCGTGGAGCATGCAACACATCCCGGC
ACTGTTTTCGGCCTTCTGTGGCCTCTTGGTCGCCCTTTCTTACCATCTGAGCCGTCAGAGCAGTGACCCATCTGTACTCATGTCCTTCAT
CCAATGCAGGCTGTTTCCTAAATTTTTACATCAAAATCTGGCAGAGTCAGCTGCTGACCCTCTCCCCAAGAAGATGAAAGATTCAGTGAC
GGATGTCTTAAAATGGGATCTCATCGTCTGCGCAGTGGTTGCTGTCCTCTCATTTGCAGTCAGCGCCAGCACTGTATTCCTGTCATTGCG
ACCATTTCTCAGCATCGTGCTGTTTGCCTTGGCTGGAGCCGTGGGGTTTGTAACACATTACGTGCTCCCTCAGCTCCGCAAGCATCATCC
CTGGATGTGGATTTCACACCCCATTCTCAAAAACAAAGAGTATCATCAACGGGAAGTGAGAGATGTTGCCCATTTAATGTGGTTCGAAAG
ACTCTATGTTTGGCTTCAGTGTTTTGAAAAATACATCTTGTACCCAGCGCTAATTTTGAATGCCCTCACTATTGATGCATTTTTAATAAG
CAATCACCGGAGACTTGGTACCCACTGGGACATTTTTCTGATGATCATTGCTGGCATGAAGCTGTTGCGGACATCATTCTGCAACCCGGT
TTACCAGTTTATTAACTTGAGCTTCACTGTCATCTTTTTCCACTTTGACTACAAAGATATTTCAGAGAGCTTCTTACTGGATTTCTTCAT
GGTGTCCATTTTATTTAGCAAGCATGACTTTGTTCGACGAGACCGGCCACTACGTGTCCTCATTGACCTCATACAGAGGACAAAAGATGC
AGTTCGTGAGCTAGATAACCTACAGTACCGAAAAATGAAAAAAATACTTTTCCAAGAGACACGGAATGGACCCTTGAATGAGTCACAGGA
GGATGAGGAAGACAGTGAACATGGAACCAGCCTGAACAGGGAAATGGACAGCCTGGGCAGCAACCATTCCATTCCAAGCATGTCCGTGAG
CACAGGCAGCCAGAGCAGCAGTGTGAACAGCATGCAGGAAGTCATGGACGAGAGCAGTTCCGAACTTGTCATGATGCACGATGACGAAAG
CACAATCAATTCCAGCTCCTCCGTCGTGCATAAGAAAGATCATGTATTCATAAGGGATGAGGCGGGCCACGGCGATCCCAGGCCTGAGCC
GCGGCCTACCCAGTCAGTTCAGAGCCAGGCCCTCCACTACCGGAACAGAGAGCGCTTTGCCACGATCAAATCAGCATCTTTGGTTACACG
ACAGATCCATGAGCATGAGCAGGAGAACGAGTTGCGGGAACAGATGTCAGGTTATAAGCGGATGCGGCGCCAGCACCAGAAGCAGCTGAT
CGCCCTGGAGAACAAGCTGAAGGCTGAGATGGACGAGCACCGCCTCAAGCTACAGAAGGAGGTGGAGACGCATGCCAACAACTCGTCCAT
CGAGCTGGAGAAGCTGGCCAAGAAGCAAGTGGCTATCATAGAAAAGGAGGCAAAGGTAGCTGCAGCAGATGAGAAGAAGTTCCAGCAACA
GATCTTGGCCCAGCAGAAGAAAGATTTGACAACTTTCTTAGAAAGTCAGAAGAAGCAGTATAAGATTTGTAAGGAAAAAATAAAAGAGGA
AATGAATGAGGACCATAGCACACCCAAGAAAGAGAAGCAAGAGCGGATCTCCAAACATAAAGAGAACTTGCAGCACACACAGGCTGAAGA
GGAAGCCCACCTTCTCACTCAACAGAGACTGTACTACGACAAAAATTGTCGTTTCTTCAAGCGGAAAATAATGATCAAGCGGCACGAGGT
GGAGCAGCAGAACATTCGGGAGGAACTAAATAAAAAGAGGACCCAGAAGGAGATGGAGCATGCCATGCTAATCCGGCACGACGAGTCCAC
CCGAGAGCTAGAGTACAGGCAGCTGCACACGTTACAGAAGCTACGCATGGATCTGATCCGTTTACAGCACCAGACGGAACTGGAAAACCA
GCTGGAGTACAATAAGAGGCGAGAAAGAGAACTGCACAGAAAGCATGTCATGGAACTTCGGCAACAGCCAAAAAACTTAAAGGCCATGGA
AATGCAAATTAAAAAACAGTTTCAGGACACTTGCAAAGTACAGACCAAACAGTATAAAGCACTCAAGAATCACCAGTTGGAAGTTACTCC
AAAGAATGAGCACAAAACAATCTTAAAGACACTGAAAGATGAGCAGACAAGAAAACTTGCCATTTTGGCAGAGCAGTATGAACAGAGTAT
AAATGAAATGATGGCCTCTCAAGCGTTACGGCTAGATGAGGCTCAAGAAGCAGAATGCCAGGCCTTGAGGCTACAGCTCCAGCAGGAAAT
GGAGCTGCTCAACGCCTACCAGAGCAAAATCAAGATGCAAACAGAGGCACAACATGAACGTGAGCTCCAGAAGCTAGAGCAGAGAGTGTC
TCTGCGCAGAGCACACCTTGAGCAGAAGATTGAAGAGGAGCTGGCTGCCCTTCAGAAGGAACGCAGCGAGAGAATAAAGAACCTATTGGA
AAGGCAAGAGCGAGAGATTGAAACTTTTGACATGGAGAGCCTCAGAATGGGATTTGGGAATTTGGTTACATTAGATTTTCCTAAGGAGGA
CTACAGATGAGATTAAATTTTTTGCCATTTACAAAAAAAAAAAAAAAAAAGAAAACAGAAAAAAATTCAGACCCTGCAAAACCACATTCC
CCATTTTAACGGGCGTTGCTCTCACTCTCTCTCTCTCTTACTCTTACTGACATCGTGTCGGACTAGTGCCTGTTTATTCTTACTCCATCA
GGGGCCCCCTTCCTCCCCCCGTGTCAACTTTCAGTGCTGGCCAAAACCTGGCCGTCTCTTCTATTCACAGTACACGTCACAGTATTGATG
TGATTCAAAATGTTTCAGTGAAAACTTTGGAGACAGTTTTAACAAAACCAATAAACCAACAACAAAAAAAGTGGATGTATATTGCTTTAA
GCAATCACTCATTACCACCAATCTGTGAAAGTAAAGCAAAAAATAATAATAATAAATGCCAAGGGGGAGAGAGACACAATATCCGCAGCC
TTACACCTTAACTAGCTGCTGCATTATTTTATTTTATTTTATTTTTTTGGTATTTATTCATCAGGAATAAAAAAAACAAAGTTTTATTAA
AGATTGAAAATTTGATACATTTTACAGAAACTAATTGTGATGTACATATCAGTGGTGACATATTATTACTTTTTTGGGGACGGGGGGTGG
GTGGGGTGAAGAGATCTTGTGATTTTTAAGAACCTGCTGGCAAGAGTTTAACTTGTCTTCAGCATATTCTGATTGTATCATAATCATTTT
CTGCTGTTGCAGAGGATGTGAATACACTTAAGGAGCTCACAGAATCCCAGTAGCACAAATTGGGCTTTGGCAAATCGTGTATTTTGTGTA
TAGAAGGAATTTAAGGAGAGGTATTACTTATTTTCATATTGTATTTTAACTGTTTCTCTGATCAAATTTTTTTACTTCCTCCTCCTGTTC
CTCCCCACCTCCCTCCTTTTCCAGTTCAGTATTTGGAGTTCAACACTGTCTCTCAATCAGATCATCTTGATCTTTTTCTTTATCTCCCTT
CCCCTTCCTAAGTCCCATTTCTTGGTCATAAATATTGCATTATTCACACTTTCAAACTGTGTATTTTCTTACAATAAAAAATGATGAAAA
AAAAAAAGGCTTTACTTCTTTTGCATGCACTTTAAAAACAAAACAAAACATTTTTCAGGTTCCAAGGAAGAGCATGATAACTGTCAGAGC

>63465_63465_3_PCNXL2-TAOK3_PCNXL2_chr1_233270761_ENST00000258229_TAOK3_chr12_118639270_ENST00000392533_length(amino acids)=1979AA_BP=1354
MPGRSSRLRRRGSRVRAEEQLQLQTWGGRRRRGRRRRRRRGRGPRARVLDLREPGDPAGARRVQRGAHQPRGAAGMVSQVLQLLRQGVWA
ALTGGWYHDPEQSKFTNSCHLYLWLFLLLLPLALHLAFPPNAIIVFFYCSAVTIFFTIIKLVSYRLHLMFDKGEVIQQKPSRKEEKPNKD
KEAKGEHITNHRNPSNNRQIHNGKKEEASRNLSTPPLRCSSRGQSITSHHSSGPLELSAQETVEDLKGVILLEDHPIAPVSSTSPGIKVE
SLPASQAHMLETTTKSVIPVKPVATETLINGKGKERGGKGQPPLRHRSEGGLVDKGPLKKLPHLSLSQYDLLETDVSFQPWGSENSVLIP
EPVSCPRGSIRERVQSKSPQDSLSSSCPQCDTIVAKPVEEPADTSCQVDTSCQGDLPLHQEVDSSDSEVAVTLIDTSQPGDPLSLHEPIK
IVITMSSTPNSMTDLESSLHLRVVGTEKTSVKSDAEPTNPGAAGSPNAEQISIPVITLDLPEGGGGGVPCPEGNGSERTPERLKTRVSTN
QCSGYGSGEGGNAIKDHSSSSREPWESVSRLTPDTGSESKVGKEGQTNLDPSSCKSSHEKRHARVLSVDSGTDVFLSKSSAEIVNDTEKT
MPTSKSDLEAKEGQMPNESNFLEFVSLLESINTSKMTASSQLNGSAEQNEESGLLRDNCSQEKKEEILENEKPSGHSSKQGKPDLQSQDH
TSTGPACTQPAKTTAFFQGNRQRQIIYRVTSQQDSSVLQVISGPETSVQEEISVDAMHVFIDEHGEIRSCYLKSGNQKEGPLQPLPSNND
CLSQAREMQVSSSSTTTSESQDPSSGDPAVSALQQQLLLMVARRTQSETPRHVSQDLEASSCSSTQGKFNREQFYKFIIFPGKWIKVWYD
RLTLLALLDRTEDIKENVLAILLIVLVSLLGFLTLSQGFCKDMWVLLFCLVMASCQYSLLKSVQPDPASPIHGHNQIITYSRPIYFCVLC
GLILLLDTGAKARHPPSYVVYGLKLFSPVFLQSARDYLIVFLYCFPAISLLGLFPQINTFCTYLLEQIDMLFFGGSAVSGITSAVYSVAR
SVLAAALLHAVCFSAVKEPWSMQHIPALFSAFCGLLVALSYHLSRQSSDPSVLMSFIQCRLFPKFLHQNLAESAADPLPKKMKDSVTDVL
KWDLIVCAVVAVLSFAVSASTVFLSLRPFLSIVLFALAGAVGFVTHYVLPQLRKHHPWMWISHPILKNKEYHQREVRDVAHLMWFERLYV
WLQCFEKYILYPALILNALTIDAFLISNHRRLGTHWDIFLMIIAGMKLLRTSFCNPVYQFINLSFTVIFFHFDYKDISESFLLDFFMVSI
LFSKHDFVRRDRPLRVLIDLIQRTKDAVRELDNLQYRKMKKILFQETRNGPLNESQEDEEDSEHGTSLNREMDSLGSNHSIPSMSVSTGS
QSSSVNSMQEVMDESSSELVMMHDDESTINSSSSVVHKKDHVFIRDEAGHGDPRPEPRPTQSVQSQALHYRNRERFATIKSASLVTRQIH
EHEQENELREQMSGYKRMRRQHQKQLIALENKLKAEMDEHRLKLQKEVETHANNSSIELEKLAKKQVAIIEKEAKVAAADEKKFQQQILA
QQKKDLTTFLESQKKQYKICKEKIKEEMNEDHSTPKKEKQERISKHKENLQHTQAEEEAHLLTQQRLYYDKNCRFFKRKIMIKRHEVEQQ
NIREELNKKRTQKEMEHAMLIRHDESTRELEYRQLHTLQKLRMDLIRLQHQTELENQLEYNKRRERELHRKHVMELRQQPKNLKAMEMQI
KKQFQDTCKVQTKQYKALKNHQLEVTPKNEHKTILKTLKDEQTRKLAILAEQYEQSINEMMASQALRLDEAQEAECQALRLQLQQEMELL

--------------------------------------------------------------
>63465_63465_4_PCNXL2-TAOK3_PCNXL2_chr1_233270761_ENST00000258229_TAOK3_chr12_118639270_ENST00000419821_length(transcript)=7146nt_BP=4072nt
TGGCGCTCACCTGCCCGGCCGCAGCAGCCGGCTCCGGCGCCGCGGTTCGCGGGTCCGGGCGGAAGAGCAGCTCCAGCTTCAAACGTGGGG
TGGAAGGAGGCGGCGGGGGCGACGGCGGCGGCGACGGCGGGGGCGCGGCCCGCGGGCCCGGGTGTTAGACCTGAGGGAGCCTGGAGATCC
GGCCGGGGCGCGCAGGGTGCAGCGGGGCGCTCACCAGCCCCGGGGCGCAGCCGGCATGGTGTCCCAGGTGCTGCAGCTGCTCCGGCAGGG
CGTGTGGGCCGCGCTCACCGGGGGCTGGTACCACGACCCGGAGCAGAGCAAGTTCACCAACAGCTGCCACCTCTACCTGTGGCTGTTCCT
CCTGCTGCTGCCCCTGGCCCTGCACCTGGCTTTTCCTCCAAATGCGATCATTGTATTTTTCTACTGCAGTGCAGTGACTATATTCTTCAC
AATAATCAAACTGGTCAGTTATCGCCTACACCTCATGTTTGACAAAGGAGAAGTAATTCAGCAAAAGCCCTCCAGAAAGGAAGAAAAGCC
AAATAAAGACAAGGAGGCCAAAGGTGAACACATAACTAATCACAGAAATCCAAGCAATAATAGGCAGATTCACAATGGCAAAAAGGAAGA
GGCCAGTCGAAACCTCTCCACGCCTCCCCTCCGCTGCAGCTCCAGAGGGCAAAGCATAACCTCTCATCACTCTTCTGGGCCATTGGAGTT
GTCAGCACAGGAAACTGTAGAAGATCTCAAAGGTGTCATTCTATTAGAAGACCATCCCATAGCACCAGTGTCATCTACCTCACCTGGTAT
CAAAGTGGAAAGCTTACCTGCGTCTCAAGCACACATGCTGGAAACCACGACCAAGTCAGTAATACCTGTAAAACCAGTTGCCACAGAAAC
TCTCATCAATGGTAAAGGAAAGGAAAGAGGAGGCAAGGGGCAGCCTCCTTTGCGCCACAGATCCGAGGGTGGCTTAGTGGATAAGGGACC
CTTGAAGAAGTTGCCCCACCTGTCTTTGTCTCAGTATGACTTACTAGAAACAGACGTTTCTTTCCAGCCGTGGGGGAGTGAGAATTCAGT
CCTGATTCCAGAACCTGTCAGTTGTCCCCGGGGCTCCATAAGGGAACGGGTACAAAGCAAGTCACCTCAGGACAGCCTGAGCAGCAGCTG
CCCTCAATGTGACACCATCGTGGCCAAGCCTGTGGAGGAGCCAGCAGACACATCCTGTCAGGTAGATACCTCCTGCCAGGGGGACCTGCC
CTTGCACCAGGAAGTGGACTCCTCAGATAGTGAGGTAGCTGTTACTCTCATCGATACTTCTCAACCCGGAGACCCACTGAGTCTACATGA
GCCCATAAAAATTGTTATCACGATGAGCAGTACCCCAAACTCCATGACAGATTTGGAAAGCTCCCTCCACCTGAGGGTGGTTGGCACAGA
GAAGACCAGTGTAAAGTCTGACGCTGAGCCCACTAACCCAGGGGCGGCCGGTTCTCCAAATGCCGAGCAGATCTCAATTCCTGTAATCAC
CCTGGACCTGCCTGAGGGTGGGGGAGGAGGTGTTCCCTGTCCCGAAGGCAATGGAAGTGAAAGGACTCCAGAGAGACTGAAGACGAGGGT
ATCCACCAATCAGTGTTCTGGCTACGGATCTGGGGAGGGGGGAAATGCCATCAAGGATCACAGTTCTTCATCACGGGAACCCTGGGAATC
GGTGTCCCGGCTTACACCTGATACAGGCTCCGAGTCTAAGGTGGGGAAGGAAGGCCAGACTAACCTTGACCCATCGTCTTGTAAGTCCAG
CCATGAAAAGAGGCATGCCCGGGTGCTCAGTGTGGACAGTGGGACAGATGTCTTCTTGAGTAAAAGTTCTGCAGAAATTGTTAACGATAC
AGAGAAAACAATGCCAACTTCCAAATCTGACCTAGAGGCTAAGGAAGGACAAATGCCAAATGAGTCCAACTTCCTGGAATTTGTCTCCCT
GTTAGAATCCATTAATACTTCCAAGATGACGGCATCCAGTCAACTGAATGGCTCAGCTGAGCAGAATGAAGAAAGTGGGCTTCTCCGAGA
TAACTGTTCCCAGGAAAAAAAGGAGGAAATCCTGGAAAATGAAAAGCCCAGTGGACACAGTTCTAAGCAAGGAAAACCAGATTTGCAAAG
TCAAGACCATACTAGCACCGGCCCCGCATGCACTCAGCCTGCCAAGACCACAGCCTTTTTTCAGGGCAATAGACAAAGACAGATAATCTA
CAGGGTAACTTCCCAACAAGATAGTTCTGTCTTGCAAGTCATCAGTGGGCCTGAAACATCTGTACAAGAAGAGATATCTGTGGATGCTAT
GCATGTCTTCATTGATGAACATGGGGAAATTAGATCCTGTTATTTAAAATCTGGAAATCAGAAAGAAGGCCCTTTACAGCCTCTACCATC
AAATAATGACTGTCTCTCTCAGGCTCGAGAGATGCAGGTCAGCTCCTCCAGTACCACAACTTCTGAGAGTCAAGATCCGTCTTCTGGGGA
CCCTGCCGTCAGTGCCCTTCAGCAACAGCTGTTACTGATGGTGGCTCGCAGGACCCAGTCGGAAACCCCACGGCATGTGAGTCAGGATCT
GGAAGCCTCGTCATGTTCTTCAACACAAGGAAAATTTAACCGAGAGCAGTTTTACAAATTTATCATTTTCCCTGGCAAGTGGATTAAAGT
CTGGTATGATCGACTGACCTTGCTGGCATTACTTGATCGAACTGAAGACATCAAGGAGAATGTACTGGCGATTTTACTCATTGTCCTGGT
TTCCCTCCTTGGATTTCTGACCTTGAGCCAAGGCTTTTGCAAAGATATGTGGGTGCTCCTCTTCTGCCTCGTCATGGCCAGCTGCCAGTA
CTCCCTGCTAAAGAGTGTTCAGCCTGACCCCGCCTCACCAATACACGGACACAACCAAATCATAACATATAGCAGACCAATCTATTTTTG
TGTGCTGTGTGGCCTTATTTTGCTTCTTGATACAGGGGCCAAAGCCAGGCACCCTCCCAGTTACGTTGTGTATGGCCTGAAGCTCTTCTC
TCCAGTGTTTCTACAATCAGCTAGGGACTACTTAATAGTATTTTTATATTGCTTCCCTGCTATTTCCCTCCTTGGGCTCTTCCCGCAAAT
CAACACTTTCTGCACTTATCTTTTGGAGCAAATTGACATGCTGTTTTTTGGTGGTTCTGCTGTGTCTGGGATAACCTCGGCTGTTTACAG
TGTGGCCCGGAGCGTCTTGGCTGCCGCCCTGCTCCACGCAGTCTGCTTCAGTGCAGTGAAGGAACCGTGGAGCATGCAACACATCCCGGC
ACTGTTTTCGGCCTTCTGTGGCCTCTTGGTCGCCCTTTCTTACCATCTGAGCCGTCAGAGCAGTGACCCATCTGTACTCATGTCCTTCAT
CCAATGCAGGCTGTTTCCTAAATTTTTACATCAAAATCTGGCAGAGTCAGCTGCTGACCCTCTCCCCAAGAAGATGAAAGATTCAGTGAC
GGATGTCTTAAAATGGGATCTCATCGTCTGCGCAGTGGTTGCTGTCCTCTCATTTGCAGTCAGCGCCAGCACTGTATTCCTGTCATTGCG
ACCATTTCTCAGCATCGTGCTGTTTGCCTTGGCTGGAGCCGTGGGGTTTGTAACACATTACGTGCTCCCTCAGCTCCGCAAGCATCATCC
CTGGATGTGGATTTCACACCCCATTCTCAAAAACAAAGAGTATCATCAACGGGAAGTGAGAGATGTTGCCCATTTAATGTGGTTCGAAAG
ACTCTATGTTTGGCTTCAGTGTTTTGAAAAATACATCTTGTACCCAGCGCTAATTTTGAATGCCCTCACTATTGATGCATTTTTAATAAG
CAATCACCGGAGACTTGGTACCCACTGGGACATTTTTCTGATGATCATTGCTGGCATGAAGCTGTTGCGGACATCATTCTGCAACCCGGT
TTACCAGTTTATTAACTTGAGCTTCACTGTCATCTTTTTCCACTTTGACTACAAAGATATTTCAGAGAGCTTCTTACTGGATTTCTTCAT
GGTGTCCATTTTATTTAGCAAGCATGACTTTGTTCGACGAGACCGGCCACTACGTGTCCTCATTGACCTCATACAGAGGACAAAAGATGC
AGTTCGTGAGCTAGATAACCTACAGTACCGAAAAATGAAAAAAATACTTTTCCAAGAGACACGGAATGGACCCTTGAATGAGTCACAGGA
GGATGAGGAAGACAGTGAACATGGAACCAGCCTGAACAGGGAAATGGACAGCCTGGGCAGCAACCATTCCATTCCAAGCATGTCCGTGAG
CACAGGCAGCCAGAGCAGCAGTGTGAACAGCATGCAGGAAGTCATGGACGAGAGCAGTTCCGAACTTGTCATGATGCACGATGACGAAAG
CACAATCAATTCCAGCTCCTCCGTCGTGCATAAGAAAGATCATGTATTCATAAGGGATGAGGCGGGCCACGGCGATCCCAGGCCTGAGCC
GCGGCCTACCCAGTCAGTTCAGAGCCAGGCCCTCCACTACCGGAACAGAGAGCGCTTTGCCACGATCAAATCAGCATCTTTGGTTACACG
ACAGATCCATGAGCATGAGCAGGAGAACGAGTTGCGGGAACAGATGTCAGGTTATAAGCGGATGCGGCGCCAGCACCAGAAGCAGCTGAT
CGCCCTGGAGAACAAGCTGAAGGCTGAGATGGACGAGCACCGCCTCAAGCTACAGAAGGAGGTGGAGACGCATGCCAACAACTCGTCCAT
CGAGCTGGAGAAGCTGGCCAAGAAGCAAGTGGCTATCATAGAAAAGGAGGCAAAGGTAGCTGCAGCAGATGAGAAGAAGTTCCAGCAACA
GATCTTGGCCCAGCAGAAGAAAGATTTGACAACTTTCTTAGAAAGTCAGAAGAAGCAGTATAAGATTTGTAAGGAAAAAATAAAAGAGGA
AATGAATGAGGACCATAGCACACCCAAGAAAGAGAAGCAAGAGCGGATCTCCAAACATAAAGAGAACTTGCAGCACACACAGGCTGAAGA
GGAAGCCCACCTTCTCACTCAACAGAGACTGTACTACGACAAAAATTGTCGTTTCTTCAAGCGGAAAATAATGATCAAGCGGCACGAGGT
GGAGCAGCAGAACATTCGGGAGGAACTAAATAAAAAGAGGACCCAGAAGGAGATGGAGCATGCCATGCTAATCCGGCACGACGAGTCCAC
CCGAGAGCTAGAGTACAGGCAGCTGCACACGTTACAGAAGCTACGCATGGATCTGATCCGTTTACAGCACCAGACGGAACTGGAAAACCA
GCTGGAGTACAATAAGAGGCGAGAAAGAGAACTGCACAGAAAGCATGTCATGGAACTTCGGCAACAGCCAAAAAACTTAAAGGCCATGGA
AATGCAAATTAAAAAACAGTTTCAGGACACTTGCAAAGTACAGACCAAACAGTATAAAGCACTCAAGAATCACCAGTTGGAAGTTACTCC
AAAGAATGAGCACAAAACAATCTTAAAGACACTGAAAGATGAGCAGACAAGAAAACTTGCCATTTTGGCAGAGCAGTATGAACAGAGTAT
AAATGAAATGATGGCCTCTCAAGCGTTACGGCTAGATGAGGCTCAAGAAGCAGAATGCCAGGCCTTGAGGCTACAGCTCCAGCAGGAAAT
GGAGCTGCTCAACGCCTACCAGAGCAAAATCAAGATGCAAACAGAGGCACAACATGAACGTGAGCTCCAGAAGCTAGAGCAGAGAGTGTC
TCTGCGCAGAGCACACCTTGAGCAGAAGATTGAAGAGGAGCTGGCTGCCCTTCAGAAGGAACGCAGCGAGAGAATAAAGAACCTATTGGA
AAGGCAAGAGCGAGAGATTGAAACTTTTGACATGGAGAGCCTCAGAATGGGATTTGGGAATTTGGTTACATTAGATTTTCCTAAGGAGGA
CTACAGATGAGATTAAATTTTTTGCCATTTACAAAAAAAAAAAAAAAAAAGAAAACAGAAAAAAATTCAGACCCTGCAAAACCACATTCC
CCATTTTAACGGGCGTTGCTCTCACTCTCTCTCTCTCTTACTCTTACTGACATCGTGTCGGACTAGTGCCTGTTTATTCTTACTCCATCA
GGGGCCCCCTTCCTCCCCCCGTGTCAACTTTCAGTGCTGGCCAAAACCTGGCCGTCTCTTCTATTCACAGTACACGTCACAGTATTGATG
TGATTCAAAATGTTTCAGTGAAAACTTTGGAGACAGTTTTAACAAAACCAATAAACCAACAACAAAAAAAGTGGATGTATATTGCTTTAA
GCAATCACTCATTACCACCAATCTGTGAAAGTAAAGCAAAAAATAATAATAATAAATGCCAAGGGGGAGAGAGACACAATATCCGCAGCC
TTACACCTTAACTAGCTGCTGCATTATTTTATTTTATTTTATTTTTTTGGTATTTATTCATCAGGAATAAAAAAAACAAAGTTTTATTAA
AGATTGAAAATTTGATACATTTTACAGAAACTAATTGTGATGTACATATCAGTGGTGACATATTATTACTTTTTTGGGGACGGGGGGTGG
GTGGGGTGAAGAGATCTTGTGATTTTTAAGAACCTGCTGGCAAGAGTTTAACTTGTCTTCAGCATATTCTGATTGTATCATAATCATTTT
CTGCTGTTGCAGAGGATGTGAATACACTTAAGGAGCTCACAGAATCCCAGTAGCACAAATTGGGCTTTGGCAAATCGTGTATTTTGTGTA
TAGAAGGAATTTAAGGAGAGGTATTACTTATTTTCATATTGTATTTTAACTGTTTCTCTGATCAAATTTTTTTACTTCCTCCTCCTGTTC
CTCCCCACCTCCCTCCTTTTCCAGTTCAGTATTTGGAGTTCAACACTGTCTCTCAATCAGATCATCTTGATCTTTTTCTTTATCTCCCTT
CCCCTTCCTAAGTCCCATTTCTTGGTCATAAATATTGCATTATTCACACTTTCAAACTGTGTATTTTCTTACAATAAAAAATGATGAAAA
AAAAAAAGGCTTTACTTCTTTTGCATGCACTTTAAAAACAAAACAAAACATTTTTCAGGTTCCAAGGAAGAGCATGATAACTGTCAGAGC

>63465_63465_4_PCNXL2-TAOK3_PCNXL2_chr1_233270761_ENST00000258229_TAOK3_chr12_118639270_ENST00000419821_length(amino acids)=1979AA_BP=1354
MPGRSSRLRRRGSRVRAEEQLQLQTWGGRRRRGRRRRRRRGRGPRARVLDLREPGDPAGARRVQRGAHQPRGAAGMVSQVLQLLRQGVWA
ALTGGWYHDPEQSKFTNSCHLYLWLFLLLLPLALHLAFPPNAIIVFFYCSAVTIFFTIIKLVSYRLHLMFDKGEVIQQKPSRKEEKPNKD
KEAKGEHITNHRNPSNNRQIHNGKKEEASRNLSTPPLRCSSRGQSITSHHSSGPLELSAQETVEDLKGVILLEDHPIAPVSSTSPGIKVE
SLPASQAHMLETTTKSVIPVKPVATETLINGKGKERGGKGQPPLRHRSEGGLVDKGPLKKLPHLSLSQYDLLETDVSFQPWGSENSVLIP
EPVSCPRGSIRERVQSKSPQDSLSSSCPQCDTIVAKPVEEPADTSCQVDTSCQGDLPLHQEVDSSDSEVAVTLIDTSQPGDPLSLHEPIK
IVITMSSTPNSMTDLESSLHLRVVGTEKTSVKSDAEPTNPGAAGSPNAEQISIPVITLDLPEGGGGGVPCPEGNGSERTPERLKTRVSTN
QCSGYGSGEGGNAIKDHSSSSREPWESVSRLTPDTGSESKVGKEGQTNLDPSSCKSSHEKRHARVLSVDSGTDVFLSKSSAEIVNDTEKT
MPTSKSDLEAKEGQMPNESNFLEFVSLLESINTSKMTASSQLNGSAEQNEESGLLRDNCSQEKKEEILENEKPSGHSSKQGKPDLQSQDH
TSTGPACTQPAKTTAFFQGNRQRQIIYRVTSQQDSSVLQVISGPETSVQEEISVDAMHVFIDEHGEIRSCYLKSGNQKEGPLQPLPSNND
CLSQAREMQVSSSSTTTSESQDPSSGDPAVSALQQQLLLMVARRTQSETPRHVSQDLEASSCSSTQGKFNREQFYKFIIFPGKWIKVWYD
RLTLLALLDRTEDIKENVLAILLIVLVSLLGFLTLSQGFCKDMWVLLFCLVMASCQYSLLKSVQPDPASPIHGHNQIITYSRPIYFCVLC
GLILLLDTGAKARHPPSYVVYGLKLFSPVFLQSARDYLIVFLYCFPAISLLGLFPQINTFCTYLLEQIDMLFFGGSAVSGITSAVYSVAR
SVLAAALLHAVCFSAVKEPWSMQHIPALFSAFCGLLVALSYHLSRQSSDPSVLMSFIQCRLFPKFLHQNLAESAADPLPKKMKDSVTDVL
KWDLIVCAVVAVLSFAVSASTVFLSLRPFLSIVLFALAGAVGFVTHYVLPQLRKHHPWMWISHPILKNKEYHQREVRDVAHLMWFERLYV
WLQCFEKYILYPALILNALTIDAFLISNHRRLGTHWDIFLMIIAGMKLLRTSFCNPVYQFINLSFTVIFFHFDYKDISESFLLDFFMVSI
LFSKHDFVRRDRPLRVLIDLIQRTKDAVRELDNLQYRKMKKILFQETRNGPLNESQEDEEDSEHGTSLNREMDSLGSNHSIPSMSVSTGS
QSSSVNSMQEVMDESSSELVMMHDDESTINSSSSVVHKKDHVFIRDEAGHGDPRPEPRPTQSVQSQALHYRNRERFATIKSASLVTRQIH
EHEQENELREQMSGYKRMRRQHQKQLIALENKLKAEMDEHRLKLQKEVETHANNSSIELEKLAKKQVAIIEKEAKVAAADEKKFQQQILA
QQKKDLTTFLESQKKQYKICKEKIKEEMNEDHSTPKKEKQERISKHKENLQHTQAEEEAHLLTQQRLYYDKNCRFFKRKIMIKRHEVEQQ
NIREELNKKRTQKEMEHAMLIRHDESTRELEYRQLHTLQKLRMDLIRLQHQTELENQLEYNKRRERELHRKHVMELRQQPKNLKAMEMQI
KKQFQDTCKVQTKQYKALKNHQLEVTPKNEHKTILKTLKDEQTRKLAILAEQYEQSINEMMASQALRLDEAQEAECQALRLQLQQEMELL

--------------------------------------------------------------

Top

Fusion Gene PPI Analysis for PCNXL2-TAOK3

Go to ChiPPI (Chimeric Protein-Protein interactions) to see the chimeric PPI interaction in
ChiPPI page.

Protein-protein interactors with each fusion partner protein in wild-type (BIOGRID-3.4.160)

Hgene

Hgene's interactors

Tgene

Tgene's interactors

- Retained PPIs in in-frame fusion.

Partner

Gene

Hbp

Tbp

ENST

Strand

BPexon

TotalExon

Protein feature loci

*BPloci

TotalLen

Still interaction with

- Lost PPIs in in-frame fusion.

Partner

Gene

Hbp

Tbp

ENST

Strand

BPexon

TotalExon

Protein feature loci

*BPloci

TotalLen

Interaction lost with

- Retained PPIs, but lost function due to frame-shift fusion.

Partner

Gene

Hbp

Tbp

ENST

Strand

BPexon

TotalExon

Protein feature loci

*BPloci

TotalLen

Interaction lost with

Top

Related Drugs for PCNXL2-TAOK3

Drugs targeting genes involved in this fusion gene.
(DrugBank Version 5.1.8 2021-05-08)

Partner

Gene

UniProtAcc

DrugBank ID

Drug name

Drug activity

Drug type

Drug status

Top

Related Diseases for PCNXL2-TAOK3

Diseases associated with fusion partners.
(DisGeNet 4.0)

Partner

Gene

Disease ID

Disease name

# pubmeds

Source