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 | Fusion Gene Summary |
| Fusion Gene ORF analysis |
| Fusion Genomic Features |
| Fusion Protein Features |
| Fusion Gene Sequence |
| Fusion Gene PPI analysis |
| Related Drugs |
| Related Diseases |
Fusion gene:PDE3B-PLCXD3 (FusionGDB2 ID:63686) |
Fusion Gene Summary for PDE3B-PLCXD3 |
 Fusion gene summary |
| Fusion gene information | Fusion gene name: PDE3B-PLCXD3 | Fusion gene ID: 63686 | Hgene | Tgene | Gene symbol | PDE3B | PLCXD3 | Gene ID | 5140 | 345557 |
| Gene name | phosphodiesterase 3B | phosphatidylinositol specific phospholipase C X domain containing 3 | |
| Synonyms | HcGIP1|cGIPDE1 | - | |
| Cytomap | 11p15.2 | 5p13.1 | |
| Type of gene | protein-coding | protein-coding | |
| Description | cGMP-inhibited 3',5'-cyclic phosphodiesterase BCGI-PDE BCGIP1cyclic GMP-inhibited phosphodiesterase Bcyclic nucleotide phosphodiesterasephosphodiesterase 3B, cGMP-inhibited | PI-PLC X domain-containing protein 3 | |
| Modification date | 20200313 | 20200313 | |
| UniProtAcc | . | . | |
| Ensembl transtripts involved in fusion gene | ENST00000282096, ENST00000455098, ENST00000534317, | ENST00000328457, ENST00000377801, | |
| Fusion gene scores | * DoF score | 10 X 6 X 6=360 | 7 X 6 X 4=168 |
| # samples | 10 | 9 | |
| ** MAII score | log2(10/360*10)=-1.84799690655495 possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs). DoF>8 and MAII<0 | log2(9/168*10)=-0.900464326449086 possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs). DoF>8 and MAII<0 | |
| Context | PubMed: PDE3B [Title/Abstract] AND PLCXD3 [Title/Abstract] AND fusion [Title/Abstract] | ||
| Most frequent breakpoint | PDE3B(14889304)-PLCXD3(41313872), # samples:2 | ||
| Anticipated loss of major functional domain due to fusion event. | |||
| * DoF score (Degree of Frequency) = # partners X # break points X # cancer types ** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10) |
| Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez |
| Partner | Gene | GO ID | GO term | PubMed ID |
| Fusion gene breakpoints across PDE3B (5'-gene) * Click on the image to open the UCSC genome browser with custom track showing this image in a new window. |
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| Fusion gene breakpoints across PLCXD3 (3'-gene) * Click on the image to open the UCSC genome browser with custom track showing this image in a new window. |
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| Fusion gene information from two resources (ChiTars 5.0 and ChimerDB 4.0) * All genome coordinats were lifted-over on hg19. * Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser. |
| Source | Disease | Sample | Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand |
| ChimerDB4 | SKCM | TCGA-GN-A8LN-01A | PDE3B | chr11 | 14889304 | - | PLCXD3 | chr5 | 41313872 | - |
| ChimerDB4 | SKCM | TCGA-GN-A8LN-01A | PDE3B | chr11 | 14889304 | + | PLCXD3 | chr5 | 41313872 | - |
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Fusion Gene ORF analysis for PDE3B-PLCXD3 |
| Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure. * Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser. |
| ORF | Henst | Tenst | Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand |
| In-frame | ENST00000282096 | ENST00000328457 | PDE3B | chr11 | 14889304 | + | PLCXD3 | chr5 | 41313872 | - |
| In-frame | ENST00000282096 | ENST00000377801 | PDE3B | chr11 | 14889304 | + | PLCXD3 | chr5 | 41313872 | - |
| In-frame | ENST00000455098 | ENST00000328457 | PDE3B | chr11 | 14889304 | + | PLCXD3 | chr5 | 41313872 | - |
| In-frame | ENST00000455098 | ENST00000377801 | PDE3B | chr11 | 14889304 | + | PLCXD3 | chr5 | 41313872 | - |
| intron-3CDS | ENST00000534317 | ENST00000328457 | PDE3B | chr11 | 14889304 | + | PLCXD3 | chr5 | 41313872 | - |
| intron-3CDS | ENST00000534317 | ENST00000377801 | PDE3B | chr11 | 14889304 | + | PLCXD3 | chr5 | 41313872 | - |
| ORFfinder result based on the fusion transcript sequence of in-frame fusion genes. |
| Henst | Tenst | Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand | Seq length (transcript) | BP loci (transcript) | Predicted start (transcript) | Predicted stop (transcript) | Seq length (amino acids) |
| ENST00000282096 | PDE3B | chr11 | 14889304 | + | ENST00000377801 | PLCXD3 | chr5 | 41313872 | - | 10309 | 3492 | 353 | 3508 | 1051 |
| ENST00000282096 | PDE3B | chr11 | 14889304 | + | ENST00000328457 | PLCXD3 | chr5 | 41313872 | - | 10116 | 3492 | 353 | 3508 | 1051 |
| ENST00000455098 | PDE3B | chr11 | 14889304 | + | ENST00000377801 | PLCXD3 | chr5 | 41313872 | - | 10048 | 3231 | 245 | 3247 | 1000 |
| ENST00000455098 | PDE3B | chr11 | 14889304 | + | ENST00000328457 | PLCXD3 | chr5 | 41313872 | - | 9855 | 3231 | 245 | 3247 | 1000 |
| DeepORF prediction of the coding potential based on the fusion transcript sequence of in-frame fusion genes. DeepORF is a coding potential classifier based on convolutional neural network by comparing the real Ribo-seq data. If the no-coding score < 0.5 and coding score > 0.5, then the in-frame fusion transcript is predicted as being likely translated. |
| Henst | Tenst | Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand | No-coding score | Coding score |
| ENST00000282096 | ENST00000377801 | PDE3B | chr11 | 14889304 | + | PLCXD3 | chr5 | 41313872 | - | 0.000232556 | 0.9997675 |
| ENST00000282096 | ENST00000328457 | PDE3B | chr11 | 14889304 | + | PLCXD3 | chr5 | 41313872 | - | 0.000227663 | 0.99977237 |
| ENST00000455098 | ENST00000377801 | PDE3B | chr11 | 14889304 | + | PLCXD3 | chr5 | 41313872 | - | 0.000381972 | 0.99961805 |
| ENST00000455098 | ENST00000328457 | PDE3B | chr11 | 14889304 | + | PLCXD3 | chr5 | 41313872 | - | 0.000375898 | 0.99962413 |
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Fusion Genomic Features for PDE3B-PLCXD3 |
| FusionAI prediction of the potential fusion gene breakpoint based on the pre-mature RNA sequence context (+/- 5kb of individual partner genes, total 20kb length sequence). FusionAI is a fusion gene breakpoint classifier based on convolutional neural network by comparing the fusion positive and negative sequence context of ~ 20K fusion gene data. From here, we can have the relative potentency of the 20K genomic sequence how individual sequnce will be likely used as the gene fusion breakpoints. |
| Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand | 1-p | p (fusion gene breakpoint) |
| Distribution of 44 human genomic features loci across 20kb length fusion breakpoint regions. We integrated a total of 44 different types of human genomic feature loci information across five big categories including virus integration sites, repeats, structural variants, chromatin states, and gene expression regulation. More details are in help page. |
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| Distribution of 44 human genomic features loci across 20kb length fusion breakpoint regions that are ovelapped with the top 1% feature importance score regions. More details are in help page. |
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Fusion Protein Features for PDE3B-PLCXD3 |
| Four levels of functional features of fusion genes Go to FGviewer search page for the most frequent breakpoint (https://ccsmweb.uth.edu/FGviewer/chr11:14889304/chr5:41313872) - FGviewer provides the online visualization of the retention search of the protein functional features across DNA, RNA, protein, and pathological levels. - How to search 1. Put your fusion gene symbol. 2. Press the tab key until there will be shown the breakpoint information filled. 4. Go down and press 'Search' tab twice. 4. Go down to have the hyperlink of the search result. 5. Click the hyperlink. 6. See the FGviewer result for your fusion gene. |
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| Main function of each fusion partner protein. (from UniProt) |
| Hgene | Tgene |
| . | . |
| FUNCTION: Transcriptional activator which is required for calcium-dependent dendritic growth and branching in cortical neurons. Recruits CREB-binding protein (CREBBP) to nuclear bodies. Component of the CREST-BRG1 complex, a multiprotein complex that regulates promoter activation by orchestrating a calcium-dependent release of a repressor complex and a recruitment of an activator complex. In resting neurons, transcription of the c-FOS promoter is inhibited by BRG1-dependent recruitment of a phospho-RB1-HDAC1 repressor complex. Upon calcium influx, RB1 is dephosphorylated by calcineurin, which leads to release of the repressor complex. At the same time, there is increased recruitment of CREBBP to the promoter by a CREST-dependent mechanism, which leads to transcriptional activation. The CREST-BRG1 complex also binds to the NR2B promoter, and activity-dependent induction of NR2B expression involves a release of HDAC1 and recruitment of CREBBP (By similarity). {ECO:0000250}. | FUNCTION: Transcriptional activator which is required for calcium-dependent dendritic growth and branching in cortical neurons. Recruits CREB-binding protein (CREBBP) to nuclear bodies. Component of the CREST-BRG1 complex, a multiprotein complex that regulates promoter activation by orchestrating a calcium-dependent release of a repressor complex and a recruitment of an activator complex. In resting neurons, transcription of the c-FOS promoter is inhibited by BRG1-dependent recruitment of a phospho-RB1-HDAC1 repressor complex. Upon calcium influx, RB1 is dephosphorylated by calcineurin, which leads to release of the repressor complex. At the same time, there is increased recruitment of CREBBP to the promoter by a CREST-dependent mechanism, which leads to transcriptional activation. The CREST-BRG1 complex also binds to the NR2B promoter, and activity-dependent induction of NR2B expression involves a release of HDAC1 and recruitment of CREBBP (By similarity). {ECO:0000250}. |
| Retention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at * Minus value of BPloci means that the break pointn is located before the CDS. |
| - In-frame and retained protein feature among the 13 regional features. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Protein feature | Protein feature note |
| Hgene | PDE3B | chr11:14889304 | chr5:41313872 | ENST00000282096 | + | 15 | 16 | 117_137 | 1046 | 1113.0 | Transmembrane | Helical |
| Hgene | PDE3B | chr11:14889304 | chr5:41313872 | ENST00000282096 | + | 15 | 16 | 152_172 | 1046 | 1113.0 | Transmembrane | Helical |
| Hgene | PDE3B | chr11:14889304 | chr5:41313872 | ENST00000282096 | + | 15 | 16 | 192_212 | 1046 | 1113.0 | Transmembrane | Helical |
| Hgene | PDE3B | chr11:14889304 | chr5:41313872 | ENST00000282096 | + | 15 | 16 | 220_240 | 1046 | 1113.0 | Transmembrane | Helical |
| Hgene | PDE3B | chr11:14889304 | chr5:41313872 | ENST00000282096 | + | 15 | 16 | 247_267 | 1046 | 1113.0 | Transmembrane | Helical |
| Hgene | PDE3B | chr11:14889304 | chr5:41313872 | ENST00000282096 | + | 15 | 16 | 88_108 | 1046 | 1113.0 | Transmembrane | Helical |
| - In-frame and not-retained protein feature among the 13 regional features. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Protein feature | Protein feature note |
| Hgene | PDE3B | chr11:14889304 | chr5:41313872 | ENST00000282096 | + | 15 | 16 | 1077_1080 | 1046 | 1113.0 | Compositional bias | Note=Poly-Glu |
| Hgene | PDE3B | chr11:14889304 | chr5:41313872 | ENST00000282096 | + | 15 | 16 | 651_1079 | 1046 | 1113.0 | Domain | PDEase |
| Tgene | PLCXD3 | chr11:14889304 | chr5:41313872 | ENST00000328457 | 1 | 4 | 22_197 | 270 | 2225.3333333333335 | Domain | PI-PLC X-box | |
| Tgene | PLCXD3 | chr11:14889304 | chr5:41313872 | ENST00000377801 | 1 | 3 | 22_197 | 270 | 322.0 | Domain | PI-PLC X-box |
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Fusion Gene Sequence for PDE3B-PLCXD3 |
| For in-frame fusion transcripts, we provide the fusion transcript sequences and fusion amino acid sequences. To have fusion amino acid sequence, we ran ORFfinder and chose the longest ORF among the all predicted ones. |
| >63686_63686_1_PDE3B-PLCXD3_PDE3B_chr11_14889304_ENST00000282096_PLCXD3_chr5_41313872_ENST00000328457_length(transcript)=10116nt_BP=3492nt GCTCGCGCGCCCAACGGACCAGGCTGGGGCCGTGAGGTAACTGTTGCAGCCAGCGGAGGTGGGAGGCGACACTGAGTCTCCAGTCCCGAG AGGTGCCCGAGGGAAAAGGAGGCGGCAGCTAAACTGGTCCTGGAGAGAAGCCCCTTCCGCCCCTCTCCTCAGCCAGCATGTCCCGGACTC CGCCGCTCCTCAGTCCGCGCGGTGGGGACCCCGGGCCGTGGCGGCCGGCGCAGCCCTGACGGGTTGCGAACCAGGGGGCGCCCCGAACGC GGGGGTTGGGGTCTGGGAGCGCGAGCGGCCGCTACGGTACGAGCGGGGTGTGCTGAGTCCCGTGGCCACCCCCGGCCCCAGCCATGAGGA GGGACGAGCGAGACGCCAAAGCCATGCGGTCCCTGCAGCCGCCGGATGGGGCCGGCTCGCCCCCCGAGAGTCTGAGGAACGGCTACGTGA AGAGCTGCGTGAGCCCCTTGCGGCAGGACCCTCCGCGCGGCTTCTTCTTCCACCTCTGCCGCTTCTGCAACGTGGAGCTGCGGCCGCCGC CGGCCTCTCCCCAGCAGCCGCGGCGCTGCTCCCCCTTCTGCCGGGCGCGCCTCTCGCTGGGCGCCCTGGCTGCCTTTGTCCTCGCCCTGC TGCTGGGCGCGGAACCCGAGAGCTGGGCTGCCGGGGCCGCCTGGCTGCGGACGCTGCTGAGCGTGTGTTCGCACAGCTTGAGCCCCCTCT TCAGCATCGCCTGTGCCTTCTTCTTCCTCACCTGCTTCCTCACCCGGACCAAGCGGGGACCCGGCCCGGGCCGGAGCTGCGGCTCCTGGT GGCTGCTGGCGCTGCCCGCCTGCTGTTACCTGGGGGACTTCTTGGTGTGGCAGTGGTGGTCTTGGCCTTGGGGGGATGGCGACGCAGGGT CCGCGGCCCCGCACACGCCCCCGGAGGCGGCAGCGGGCAGGTTGCTGCTGGTGCTGAGCTGCGTAGGGCTGCTGCTGACGCTCGCGCACC CGCTGCGGCTCCGGCACTGCGTTCTGGTGCTGCTCCTGGCCAGCTTCGTCTGGTGGGTCTCCTTCACCAGCCTCGGGTCGCTGCCCTCCG CCCTCAGGCCGCTGCTCTCCGGCCTGGTGGGGGGCGCTGGCTGCCTGCTGGCCCTGGGGTTGGATCACTTCTTTCAAATCAGGGAAGCGC CTCTTCATCCTCGACTGTCCAGTGCCGCCGAAGAAAAAGTGCCTGTGATCCGACCCCGGAGGAGGTCCAGCTGCGTGTCGTTAGGAGAAA CTGCAGCCAGTTACTATGGCAGTTGCAAAATATTCAGGAGACCGTCGTTGCCTTGTATTTCCAGAGAACAGATGATTCTTTGGGATTGGG ACTTAAAACAATGGTATAAGCCTCATTATCAAAATTCTGGAGGTGGAAATGGAGTTGATCTTTCAGTGCTAAATGAGGCTCGCAATATGG TGTCAGATCTTCTGACTGATCCAAGCCTTCCACCACAAGTCATTTCCTCTCTACGGAGTATTAGTAGCTTAATGGGTGCTTTCTCAGGTT CCTGTAGGCCAAAGATTAATCCTCTCACACCATTTCCTGGATTTTACCCCTGTTCTGAAATAGAGGACCCAGCTGAGAAAGGGGATAGAA AACTTAACAAGGGACTAAATAGGAATAGTTTGCCAACTCCACAGCTGAGGAGAAGCTCAGGAACTTCAGGATTGCTACCTGTTGAACAGT CTTCAAGGTGGGATCGTAATAATGGCAAAAGACCTCACCAAGAATTTGGCATTTCAAGTCAAGGATGCTATCTAAATGGGCCTTTTAATT CAAATCTACTGACTATCCCGAAGCAAAGGTCATCTTCTGTATCACTGACTCACCATGTAGGTCTCAGAAGAGCTGGTGTTTTGTCCAGTC TGAGTCCTGTGAATTCTTCCAACCATGGACCAGTGTCTACTGGCTCTCTAACTAATCGATCACCCATAGAATTTCCTGATACTGCTGATT TTCTTAATAAGCCAAGCGTTATCTTGCAGAGATCTCTGGGCAATGCACCTAATACTCCAGATTTTTATCAGCAACTTAGAAATTCTGATA GCAATCTGTGTAACAGCTGTGGACATCAAATGCTGAAATATGTTTCAACATCTGAATCAGATGGTACAGATTGCTGCAGTGGAAAATCAG GTGAAGAAGAAAACATTTTCTCGAAAGAATCATTCAAACTTATGGAAACTCAACAAGAAGAGGAAACAGAGAAGAAAGACAGCAGAAAAT TATTTCAGGAAGGTGATAAGTGGCTAACAGAAGAGGCACAGAGTGAACAGCAAACAAATATTGAACAGGAAGTATCACTGGACCTGATTT TAGTAGAAGAGTATGACTCATTAATAGAAAAGATGAGCAACTGGAATTTTCCAATTTTTGAACTTGTAGAAAAGATGGGAGAGAAATCAG GAAGGATTCTCAGTCAGGTTATGTATACCTTATTTCAAGACACTGGTTTATTGGAAATATTTAAAATTCCCACTCAACAATTTATGAACT ATTTTCGTGCATTAGAAAATGGCTATCGAGACATTCCTTATCACAATCGTATACATGCCACAGATGTGCTACATGCAGTTTGGTATCTGA CAACACGGCCAGTTCCTGGCTTACAGCAGATCCACAATGGTTGTGGAACAGGAAATGAAACAGATTCTGATGGTAGAATTAACCATGGGC GAATTGCTTATATTTCTTCGAAGAGCTGCTCTAATCCTGATGAGAGTTATGGCTGCCTGTCTTCAAACATTCCTGCATTAGAATTGATGG CTCTATACGTGGCAGCTGCCATGCATGATTATGATCACCCAGGGAGGACAAATGCATTTCTAGTGGCTACAAATGCCCCTCAGGCAGTTT TATACAATGACAGATCTGTTCTGGAAAATCATCATGCTGCGTCAGCTTGGAATCTATATCTTTCTCGCCCAGAATACAACTTCCTTCTTC ATCTTGATCATGTGGAATTCAAGCGCTTTCGTTTTTTAGTCATTGAAGCAATCCTTGCTACGGATCTTAAAAAGCATTTTGATTTTCTCG CAGAATTCAATGCCAAGGCAAATGATGTAAATAGTAATGGCATAGAATGGAGTAATGAAAATGATCGCCTCTTGGTATGCCAGGTGTGCA TCAAACTGGCAGATATAAATGGCCCAGCAAAAGTTCGAGACTTGCATTTGAAATGGACAGAAGGCATTGTCAATGAATTTTATGAGCAGG GAGATGAAGAAGCAAATCTTGGTCTGCCCATCAGTCCATTCATGGATCGTTCTTCTCCTCAACTAGCAAAACTCCAAGAATCTTTTATCA CCCACATAGTGGGTCCCCTGTGTAACTCCTATGATGCTGCTGGTTTGCTACCAGGTCAGTGGTTAGAAGCAGAAGAGGATAATGATACTG AAAGTGGTGATGATGAAGACGGTGAAGAATTAGATACAGAAGATGAAGAAATGGAAAACAATCTAAATCCAAAGCTCTTCCTGCCATGAT GCAGTGGGTCCGCACGCAGAAGCCAGGAGAGAGTGGCATCAATATTGTCACTGCCGATTTTGTAGAACTTGGTGACTTTATCAGCACTGT CATAAAGCTCAACTATGTCTTTGATGAAGGAGAAGCCAACACTTGATAGCACTACTTGGAGTTTCCATGAATAAGATGGAGAAAGCTCAT TGTATTAGGGCATACTATCTGTAAACACTCTGATCTTCCTATTCCACTGAGTCTCTGAAGGGAATAGGGCTGGTAGTGGGTGGGAAAAGG GGAAAAACTGTTTCTTCAGTGATTACAATCATACTCTTCATTACTATAAATATTTCATTTCCCATTTGATGAGCAAAATCTACTTCTAGT GTTAGGAATAAAAAAAAAAGACCAGTAACTTTGTTTTTCAAAATTAGTCTTTGTAACATAGAATTCATGAGTGTTTACTTGATTAGGTTC TCTATTTCCAGCCTATGACTCCTACGCTGTCTATACCCTGCAACCTTTCTGCTCCCTCTCTTGCTCGCTCTTTTTAATCAGATGCTGTAT GGGAATCAAAACAATTGAATGCCCAACATTTTGTGTATTACATTGTTGTCTTAAAACTTACTAGTTTTGTGGGACTTGTTATAATGCTCT ATAGTCATCCACAGTTGGGCAATCATAGCTAATTTTTGGTCATAGAAAATCTGCATCAAATCAGTTTCCATGCATCAGTAATATTGAAGG TCATAATCAGTGATTTTTGTTATATGAAAATAATAGTGTTTCACAGTATTTCTATTTAAGGCAGCTATAAATATAGGAGAAAAATGTTTT TGGAGAGCTGTGAATGCCAATTTCAGAGGGAAAAATGGTTGAGGGGTGAAAGAGATGTATGGCATTTTAATTTGGCAATCTCTTAAATAA TATTGCCCTGCAAGTACCCAGTAAATGGTAAGGTACAAGTGTGTTAAAATTGAAAACTCTGAAAATAACTCTTTAAAAAGCCCTCTTAAT GATGCTCTTGATGAAAGAAAAAGACAGAAGGAAGGAAGAAGAAAAAGACTGCAAGCTTTCCTGCCAATTTGGGATTTTCAAATATTTAAT TCTAAATTCCAGATTTTAAGGAAGATTTTTCAAGAAACTGCAAGTTTTTGACTTGAAGGAAAGAAAGAGGAAGGCTGGTAGAAGCAGTTA GAGCAATGTGTTTGAAATTATGTCCATGAAATCACAGGGATCTCTGAAATATCTTTAGGAAACTTGAAATTTATGAGGTCTGAATGGACT TGTTTAAAATTGGCTCTGACTCCTCACTTCTGAGTTTCATCCTATCCGAGGGATGAGATTAAGGCAGAGGCAAAAGTTTCACACAAAGTT TCTGCAACCTAACGTTTAATAGTCCGGGTCTACAGGGAAGAACAATGACACAGCTTGAGCGTTACTTCCTCCTTCGTGTCATTGTGATAT TTGACAACTCTAAAAAATAAAAAAAAAAAACTTAGAGCACAATAATCCTTGCCTATGTACTTCACAGGAATATTGTGAGGTGTTTATAAA ATTATAAAATTTGATGAAATTCTTACAATTATTAATTATTTTATTTTCATGTTTAGAAATAATCACACCCCAATAGTTTCCTAGGATAAT ACAGTCCATGCAAAGTAGGGTCATAGAGAAATAAAAGCATGCCCTCAGCTTTTAATGAACTTAAATGTAGCACATATGGCTTAATCTCTT AGACTTAGATAAGGGAGTTCAATTCAAAACCATATATGTCAAGACCACAAATAATCAAGAGTTGATTTCAAGATTATAAATACTCATGAT CAGAAAATAGTACTTATTAGCAATTAAAGGGAGGAAAAGAAATTGTTTATACTGAAGAGAATGTTTATGAGGAGTGTGTATGTACCTGTG GTATACCAAATAGCATACATGTACACACAAAAATGTGTGTATACATTTGGGTTGTGTGTATACATCTTGCCATATACAATATACAAACAT ATGCCCATTCCTGTGATAGCATACAAATTCAAACATACAGAAACACACACAGATATGGACACAGTACAATTCTTCTTTTCAAATGAAGAC ATTGATAATATTAAATAATTTAATTTTAAGACTGAAACCCTTAATATTGTGTGAAAAAGAGTAATAAAACCTTTGAAAGTAGAGTAGATG ATCACATCAAAGTATTTTTGTAAAAGAATTCTAGTGTAGGACTTAATTATTTTTAAAATATATTTCTTCTCTTCTTTCCATTTTCCCTTC CCTTGTAGTTTTATTATCTTTCTGTCTTTTACACCTGCTCTTTATGTGAAAATGTATATGAATCCTTTTAAAATGATTAGGATTATTGAA ATGTATGTCCCGTAAATTTGGTTTTTGGGCAGACTTTCTCTCTAACTGGCTATTCATTCATCCTTCAGGAGGATCTTAGCCAAGAATATT TGCAATGACACATGAATTTAATTTTATAAATATAATGGAAAACAGATTTTTCATCATATCATGAATAAAATATAGAGGTAACTATGTTGT ATTTTCTTGAACCTAGATACTTTCTCATAGTGTTTGCTTAGAATTAACTTTGTCCTATTTGTCAACTGGGTTCTGGAAAAAAACAAACAT GATGAAGCTTTTGAATAATTGTGCAGTTTTTTAACTAGGGAAAGCTTTGTACTGCTGCTAATGATATGCACCCAGAAACCTTGTTAGACA AAAGGCAGTTTCAAGCCAATGCTATGGTTTCCATGTGGACATACAGTGCCTATGTAGCAGGCACTTAGAGTAAATGGACTTGCCTTAATT TATAAAGGAGGGAAGAGGTAGAAGGGAACCATGGGTCCTCCAGCTAGAGGGGGAGTTTACTAAAAGGGAGTCCTTGGAAAGGGGAATGGA GAGAAGGTGCCTTTGACTGTCTTCTATCCATTAGTTCTGCCCTGGAGCACACTGGGGAAGCAGGCTGCGGGCCTTCCAAAAGTAAAAAAT GGTGATATGCAATCGAAGCTTATCCTTAGCCTATGCACATTTGTCTCAGCTGGGCATTGTCTTTTCAGAGAGCTTGTAGCACAAGGGCTA CACATGGGCGCCAAGATGGTGGTAGATACACCTTGGTGCACTTTTTGTTTTACTTGTTTCTTAAGACTATTTCACAAGTCCTGTGAGGCA AAAAAACAAAACAAAACAAAACAACCAAACAAATACAATCTAACTTTTACCCAATCTACAGCAGGAAATCAAAGGAGTGGGTGGAATGAG AGAAAATATGCAAAGAGATCATTTTTAAGTTTGATTTCCTGTCTGTAATTTTCAAGGACTAATATAGCAAATTTTTCTTCTGCCATTATC ATTTATGTCTCCCTATTTACCACACAATAATGTAAATGCAGAGAATGAGGAGGCATCTTTTAAAAGCCTTAGGATATTCTATATGATGAC CTCAATATTGACTTTCAGCCATACTGGGAAAACTTACTTTTCATGGAGTGCCACCTAACAGTGAATGTATTAGAGTATAAAATGTTTGCC ATGTATACACCTGTATGTGCACATACACACATTACACACACACACAGAATGCACATTTCACACACATATACTTATTATTCAAGTTGAAAC TGCACTCTAATCAATCTGAGTCTATTGCTGTTTCAACTCTTAAAATCAATATCTCCTACATTAGTAGATATAAACATAATTCAAATATTT AAATATTTAAGAGGAGAAAAGTAACTAGAAAACCAATGAAAAGTGAGGCCATCAGAAATAGAAAATGCCTGGCACGAACAGTCTATCTAA ATTCTCAATTTCACTTCAAATTAGAGAATCCATAATGGACTAGAATATAAATTACAAACACATACACACATCTTCACTTAAAGTTGTTTT AAGTTCTTTGAAGTTCTGACATGTTTTTAGCCAGGGTTATTTGTTCAGGTTCTTCCTTGTTAGGATTCCAGACTGGAAAGTTGGAAGTCT CAGGAAATGCATGTTTCCATGAGTTTTTTAGTTTCACAGTTTTACAGATCCAACGACACAATCTTTTAATCTTTGGTCACTCAACCAAAC AGGAGTTCCGTAGGCAGAGTGCTCACTTTGAATTGCTAATAGAAAATAATGCACAGTGTCCTCAGGATATGCTAAACAAGGTTTTTAAGA GCATTTTATTTTACAGCACTTTAGTCTTTTCAGCTAGATTTCAGTGACACTATGGTGTAAATGCTATATCTGCCATAACTTATTGGTGGC TCCTGTGTTACATACAGTTTTAAATAATGCTCTAAATTGTTTGTTTTCCCAATGATAATGATAAAGTGTTCTGTAGAATTTGTAAAACAT GTCAATTGAATCTGTTGAAAATTGTGTAATTGTTATTTCAATTGTGATACTATTTTGTAGGTAATAGTTTTAAACGTATATTTGTATGAG TCAAAAGTATGTGCTTGTATGTGGTATGTGTGTGTAAGTATATAATATCTTATCAAAAATCAAACTTATCCTAAAGAAAAAGGGCACATT GTGACCAGCCTTAATTTATTAACACTTTTTTGTTGTTTTTGCAATTTGGATTTAAAATTGAAACAGAAATTAAGTTTTTGTTAAAAATGG TGTCTTTTAATTTTGTGAGGAATGGGCTTTAGAACCTATCTGAGTTCCCACAAGCAAACTGTCCACCTTGTGAGGTACCCCATTGCTTTT CGTAATAATCAAACATCAATTCATATATTAACTTCATTTTCATACAGACTAATTTGTTTTCATCAACAATAGAACCAGTACACCTTTAAA GTTGACCTTCCCAACATGGCACCCATTTTTCTTTAATGATAAATTTTCCATGAAAAATTGTTTCTCCAAACCATTACTTTTTAAAATTCA ATCTTCCCAAGTAAGATGAACTGCCTTGGTGTTAGGAGAGCTTTTAAAGGCCCATCCATACTAGGTGGTTCCAACATGGTTCTCTTCTCG AGAAAACAAGCATGCAACCCACACACTTTTCTGGTCTGCCCCACGTGTAGAATTAGTCTAGCAATAGAAAACTCATGACTGACAAGGATC TACACATGTGGTCATGCTTGAAGCAAAAATTCTGTGACCTTCTTTGGGCTTGGATCTGATTACAGAATATTAATTAACTTTCTTATTTCC TTTCTTTCTCCATCCTTAGTTATTCCTTTTCAATATTTAGAGTTGCCAGGTAAAATACAGGATATCCAGTGAAATTTAAATTTCAGATAA ACAGTATTTCTTTAGCATATTTCTCATATATTTAATCAGACATACTTTCACTTTAAAAAAAGTTTATCTGAAATTCAAATGTAACTGGGT ATGTCCTATATATTTTTTCCTAAATCTCACAATTCTATCCACACTGCCTTTCTATCTTTTTCAGCTGGGCTATCTATAAGGGGCGAGATC TACCTCCCTCCATACCCTTGTGTTCAGACACCTTATGAATATCTGCAGTCATAATGTCCTTCAAGAAAGAAAACATTGGTCAGCTCTAGG TCCTGCAAATGCTTTTTGAAGGACGAACTCAAATACAGATGGGATAATCAAGTAAATATCTTCATAGGATCAATGCCACCATGTTCAACA CTTCCCTTTGCCAGCCTGTTGTGAGGTCCAAGTTTCCCCATTAATCCCTTATATAGCATTTCCCAGTAACTGGGACAACCAAAAACACAC CGACATATTAGAAATGCTCCTGAAAAGTGGCAACACCGCCTAACTCAGTACCAGGACCTCTTTTAAATTCAATTTCTTTTTTCTTTCAGA GAGATAACAAACGAATTCATTATTTCCCCCATTCACATCTTACCACAAATTATTTTTATCAGGTTAAAACTGGTCATCTACGGAATTGTA GAAAGGTGACATAGGAACTGTCTTCACTGCTGGAAGAATAAAAGAGTCTGAGGTATAGACACTGCCCTGGTGACACCTTCTCAGAACATT GTTGGGGGACAGGGGAGGCAGGCGCAAGTAGGGGATAGAATCTGACCCTGACATGCAGCTATCACCTGGCAGAGAGACTCGTCAAAGCAA ATTATAACGACCAGTACTATTTTTTTTTGGAATTGAAAACCCAAGAAGCCCTAAAATAAGAACAGTGAGATCAAAGGCTGGTTTCTAAAA CAATGCAGAAAATAGAACCATGTTGGAATTCCTAAATTCTAGCTTTCAAATACTACTGTTTCCAACAGTGAATCCTTGACAGAGACTGAA TGCAGATGGAATTTTGAAACATTTTCAGTAGCTACCTCCTCTCCTGAAATTCCTATAAGTGGCAGAGGAAAATCCAAATCCTTTAATATA ACATGTCCATCTCATGACTCCTGCTTACACACATTTGTGTTGATTTGCTTCATTTCTGGAGGATGGGAATTTGCAGAGCTGGTGACATTT CCTTCATTAGACACCAGAAATTCACCAGAGAGAGACAGATCTGTGCCTTCTCTTTTTAGGATCTGGTTATTGATACTTTAATAAATGTGG TGTAAAGAAAATCCATGGCTACAGTCTGTATAGAAAATGTGAATTTTTTAAATAAGATTGTGTTCTTAATGTAAAAAATAAAAGTTTATT >63686_63686_1_PDE3B-PLCXD3_PDE3B_chr11_14889304_ENST00000282096_PLCXD3_chr5_41313872_ENST00000328457_length(amino acids)=1051AA_BP= MRRDERDAKAMRSLQPPDGAGSPPESLRNGYVKSCVSPLRQDPPRGFFFHLCRFCNVELRPPPASPQQPRRCSPFCRARLSLGALAAFVL ALLLGAEPESWAAGAAWLRTLLSVCSHSLSPLFSIACAFFFLTCFLTRTKRGPGPGRSCGSWWLLALPACCYLGDFLVWQWWSWPWGDGD AGSAAPHTPPEAAAGRLLLVLSCVGLLLTLAHPLRLRHCVLVLLLASFVWWVSFTSLGSLPSALRPLLSGLVGGAGCLLALGLDHFFQIR EAPLHPRLSSAAEEKVPVIRPRRRSSCVSLGETAASYYGSCKIFRRPSLPCISREQMILWDWDLKQWYKPHYQNSGGGNGVDLSVLNEAR NMVSDLLTDPSLPPQVISSLRSISSLMGAFSGSCRPKINPLTPFPGFYPCSEIEDPAEKGDRKLNKGLNRNSLPTPQLRRSSGTSGLLPV EQSSRWDRNNGKRPHQEFGISSQGCYLNGPFNSNLLTIPKQRSSSVSLTHHVGLRRAGVLSSLSPVNSSNHGPVSTGSLTNRSPIEFPDT ADFLNKPSVILQRSLGNAPNTPDFYQQLRNSDSNLCNSCGHQMLKYVSTSESDGTDCCSGKSGEEENIFSKESFKLMETQQEEETEKKDS RKLFQEGDKWLTEEAQSEQQTNIEQEVSLDLILVEEYDSLIEKMSNWNFPIFELVEKMGEKSGRILSQVMYTLFQDTGLLEIFKIPTQQF MNYFRALENGYRDIPYHNRIHATDVLHAVWYLTTRPVPGLQQIHNGCGTGNETDSDGRINHGRIAYISSKSCSNPDESYGCLSSNIPALE LMALYVAAAMHDYDHPGRTNAFLVATNAPQAVLYNDRSVLENHHAASAWNLYLSRPEYNFLLHLDHVEFKRFRFLVIEAILATDLKKHFD FLAEFNAKANDVNSNGIEWSNENDRLLVCQVCIKLADINGPAKVRDLHLKWTEGIVNEFYEQGDEEANLGLPISPFMDRSSPQLAKLQES -------------------------------------------------------------- >63686_63686_2_PDE3B-PLCXD3_PDE3B_chr11_14889304_ENST00000282096_PLCXD3_chr5_41313872_ENST00000377801_length(transcript)=10309nt_BP=3492nt GCTCGCGCGCCCAACGGACCAGGCTGGGGCCGTGAGGTAACTGTTGCAGCCAGCGGAGGTGGGAGGCGACACTGAGTCTCCAGTCCCGAG AGGTGCCCGAGGGAAAAGGAGGCGGCAGCTAAACTGGTCCTGGAGAGAAGCCCCTTCCGCCCCTCTCCTCAGCCAGCATGTCCCGGACTC CGCCGCTCCTCAGTCCGCGCGGTGGGGACCCCGGGCCGTGGCGGCCGGCGCAGCCCTGACGGGTTGCGAACCAGGGGGCGCCCCGAACGC GGGGGTTGGGGTCTGGGAGCGCGAGCGGCCGCTACGGTACGAGCGGGGTGTGCTGAGTCCCGTGGCCACCCCCGGCCCCAGCCATGAGGA GGGACGAGCGAGACGCCAAAGCCATGCGGTCCCTGCAGCCGCCGGATGGGGCCGGCTCGCCCCCCGAGAGTCTGAGGAACGGCTACGTGA AGAGCTGCGTGAGCCCCTTGCGGCAGGACCCTCCGCGCGGCTTCTTCTTCCACCTCTGCCGCTTCTGCAACGTGGAGCTGCGGCCGCCGC CGGCCTCTCCCCAGCAGCCGCGGCGCTGCTCCCCCTTCTGCCGGGCGCGCCTCTCGCTGGGCGCCCTGGCTGCCTTTGTCCTCGCCCTGC TGCTGGGCGCGGAACCCGAGAGCTGGGCTGCCGGGGCCGCCTGGCTGCGGACGCTGCTGAGCGTGTGTTCGCACAGCTTGAGCCCCCTCT TCAGCATCGCCTGTGCCTTCTTCTTCCTCACCTGCTTCCTCACCCGGACCAAGCGGGGACCCGGCCCGGGCCGGAGCTGCGGCTCCTGGT GGCTGCTGGCGCTGCCCGCCTGCTGTTACCTGGGGGACTTCTTGGTGTGGCAGTGGTGGTCTTGGCCTTGGGGGGATGGCGACGCAGGGT CCGCGGCCCCGCACACGCCCCCGGAGGCGGCAGCGGGCAGGTTGCTGCTGGTGCTGAGCTGCGTAGGGCTGCTGCTGACGCTCGCGCACC CGCTGCGGCTCCGGCACTGCGTTCTGGTGCTGCTCCTGGCCAGCTTCGTCTGGTGGGTCTCCTTCACCAGCCTCGGGTCGCTGCCCTCCG CCCTCAGGCCGCTGCTCTCCGGCCTGGTGGGGGGCGCTGGCTGCCTGCTGGCCCTGGGGTTGGATCACTTCTTTCAAATCAGGGAAGCGC CTCTTCATCCTCGACTGTCCAGTGCCGCCGAAGAAAAAGTGCCTGTGATCCGACCCCGGAGGAGGTCCAGCTGCGTGTCGTTAGGAGAAA CTGCAGCCAGTTACTATGGCAGTTGCAAAATATTCAGGAGACCGTCGTTGCCTTGTATTTCCAGAGAACAGATGATTCTTTGGGATTGGG ACTTAAAACAATGGTATAAGCCTCATTATCAAAATTCTGGAGGTGGAAATGGAGTTGATCTTTCAGTGCTAAATGAGGCTCGCAATATGG TGTCAGATCTTCTGACTGATCCAAGCCTTCCACCACAAGTCATTTCCTCTCTACGGAGTATTAGTAGCTTAATGGGTGCTTTCTCAGGTT CCTGTAGGCCAAAGATTAATCCTCTCACACCATTTCCTGGATTTTACCCCTGTTCTGAAATAGAGGACCCAGCTGAGAAAGGGGATAGAA AACTTAACAAGGGACTAAATAGGAATAGTTTGCCAACTCCACAGCTGAGGAGAAGCTCAGGAACTTCAGGATTGCTACCTGTTGAACAGT CTTCAAGGTGGGATCGTAATAATGGCAAAAGACCTCACCAAGAATTTGGCATTTCAAGTCAAGGATGCTATCTAAATGGGCCTTTTAATT CAAATCTACTGACTATCCCGAAGCAAAGGTCATCTTCTGTATCACTGACTCACCATGTAGGTCTCAGAAGAGCTGGTGTTTTGTCCAGTC TGAGTCCTGTGAATTCTTCCAACCATGGACCAGTGTCTACTGGCTCTCTAACTAATCGATCACCCATAGAATTTCCTGATACTGCTGATT TTCTTAATAAGCCAAGCGTTATCTTGCAGAGATCTCTGGGCAATGCACCTAATACTCCAGATTTTTATCAGCAACTTAGAAATTCTGATA GCAATCTGTGTAACAGCTGTGGACATCAAATGCTGAAATATGTTTCAACATCTGAATCAGATGGTACAGATTGCTGCAGTGGAAAATCAG GTGAAGAAGAAAACATTTTCTCGAAAGAATCATTCAAACTTATGGAAACTCAACAAGAAGAGGAAACAGAGAAGAAAGACAGCAGAAAAT TATTTCAGGAAGGTGATAAGTGGCTAACAGAAGAGGCACAGAGTGAACAGCAAACAAATATTGAACAGGAAGTATCACTGGACCTGATTT TAGTAGAAGAGTATGACTCATTAATAGAAAAGATGAGCAACTGGAATTTTCCAATTTTTGAACTTGTAGAAAAGATGGGAGAGAAATCAG GAAGGATTCTCAGTCAGGTTATGTATACCTTATTTCAAGACACTGGTTTATTGGAAATATTTAAAATTCCCACTCAACAATTTATGAACT ATTTTCGTGCATTAGAAAATGGCTATCGAGACATTCCTTATCACAATCGTATACATGCCACAGATGTGCTACATGCAGTTTGGTATCTGA CAACACGGCCAGTTCCTGGCTTACAGCAGATCCACAATGGTTGTGGAACAGGAAATGAAACAGATTCTGATGGTAGAATTAACCATGGGC GAATTGCTTATATTTCTTCGAAGAGCTGCTCTAATCCTGATGAGAGTTATGGCTGCCTGTCTTCAAACATTCCTGCATTAGAATTGATGG CTCTATACGTGGCAGCTGCCATGCATGATTATGATCACCCAGGGAGGACAAATGCATTTCTAGTGGCTACAAATGCCCCTCAGGCAGTTT TATACAATGACAGATCTGTTCTGGAAAATCATCATGCTGCGTCAGCTTGGAATCTATATCTTTCTCGCCCAGAATACAACTTCCTTCTTC ATCTTGATCATGTGGAATTCAAGCGCTTTCGTTTTTTAGTCATTGAAGCAATCCTTGCTACGGATCTTAAAAAGCATTTTGATTTTCTCG CAGAATTCAATGCCAAGGCAAATGATGTAAATAGTAATGGCATAGAATGGAGTAATGAAAATGATCGCCTCTTGGTATGCCAGGTGTGCA TCAAACTGGCAGATATAAATGGCCCAGCAAAAGTTCGAGACTTGCATTTGAAATGGACAGAAGGCATTGTCAATGAATTTTATGAGCAGG GAGATGAAGAAGCAAATCTTGGTCTGCCCATCAGTCCATTCATGGATCGTTCTTCTCCTCAACTAGCAAAACTCCAAGAATCTTTTATCA CCCACATAGTGGGTCCCCTGTGTAACTCCTATGATGCTGCTGGTTTGCTACCAGGTCAGTGGTTAGAAGCAGAAGAGGATAATGATACTG AAAGTGGTGATGATGAAGACGGTGAAGAATTAGATACAGAAGATGAAGAAATGGAAAACAATCTAAATCCAAAGCTCTTCCTGCCATGAT GCAGTGGGTCCGCACGCAGAAGCCAGGAGAGAGTGGCATCAATATTGTCACTGCCGATTTTGTAGAACTTGGTGACTTTATCAGCACTGT CATAAAGCTCAACTATGTCTTTGATGAAGGAGAAGCCAACACTTGATAGCACTACTTGGAGTTTCCATGAATAAGATGGAGAAAGCTCAT TGTATTAGGGCATACTATCTGTAAACACTCTGATCTTCCTATTCCACTGAGTCTCTGAAGGGAATAGGGCTGGTAGTGGGTGGGAAAAGG GGAAAAACTGTTTCTTCAGTGATTACAATCATACTCTTCATTACTATAAATATTTCATTTCCCATTTGATGAGCAAAATCTACTTCTAGT GTTAGGAATAAAAAAAAAAGACCAGTAACTTTGTTTTTCAAAATTAGTCTTTGTAACATAGAATTCATGAGTGTTTACTTGATTAGGTTC TCTATTTCCAGCCTATGACTCCTACGCTGTCTATACCCTGCAACCTTTCTGCTCCCTCTCTTGCTCGCTCTTTTTAATCAGATGCTGTAT GGGAATCAAAACAATTGAATGCCCAACATTTTGTGTATTACATTGTTGTCTTAAAACTTACTAGTTTTGTGGGACTTGTTATAATGCTCT ATAGTCATCCACAGTTGGGCAATCATAGCTAATTTTTGGTCATAGAAAATCTGCATCAAATCAGTTTCCATGCATCAGTAATATTGAAGG TCATAATCAGTGATTTTTGTTATATGAAAATAATAGTGTTTCACAGTATTTCTATTTAAGGCAGCTATAAATATAGGAGAAAAATGTTTT TGGAGAGCTGTGAATGCCAATTTCAGAGGGAAAAATGGTTGAGGGGTGAAAGAGATGTATGGCATTTTAATTTGGCAATCTCTTAAATAA TATTGCCCTGCAAGTACCCAGTAAATGGTAAGGTACAAGTGTGTTAAAATTGAAAACTCTGAAAATAACTCTTTAAAAAGCCCTCTTAAT GATGCTCTTGATGAAAGAAAAAGACAGAAGGAAGGAAGGAAGGAAGGAAGGAAGGAAGGAAGGAAGGAAGGAAGGAAAGGAAGAAAGGAA GGGAGGGAGGAAGGGAGGGAAGAAGGGAGGGAAGGACAGAAGGAAGGACGGGAGGAAGGAAGGAAGGGAGGAAGGAAGGAAGGAAGAGAG GGAGGGAGGGAGGAAGAGAGGGAGGGAGGGAGGAAGAGAGGAAGGAAGAAGAAAAAGACTGCAAGCTTTCCTGCCAATTTGGGATTTTCA AATATTTAATTCTAAATTCCAGATTTTAAGGAAGATTTTTCAAGAAACTGCAAGTTTTTGACTTGAAGGAAAGAAAGAGGAAGGCTGGTA GAAGCAGTTAGAGCAATGTGTTTGAAATTATGTCCATGAAATCACAGGGATCTCTGAAATATCTTTAGGAAACTTGAAATTTATGAGGTC TGAATGGACTTGTTTAAAATTGGCTCTGACTCCTCACTTCTGAGTTTCATCCTATCCGAGGGATGAGATTAAGGCAGAGGCAAAAGTTTC ACACAAAGTTTCTGCAACCTAACGTTTAATAGTCCGGGTCTACAGGGAAGAACAATGACACAGCTTGAGCGTTACTTCCTCCTTCGTGTC ATTGTGATATTTGACAACTCTAAAAAATAAAAAAAAAAAACTTAGAGCACAATAATCCTTGCCTATGTACTTCACAGGAATATTGTGAGG TGTTTATAAAATTATAAAATTTGATGAAATTCTTACAATTATTAATTATTTTATTTTCATGTTTAGAAATAATCACACCCCAATAGTTTC CTAGGATAATACAGTCCATGCAAAGTAGGGTCATAGAGAAATAAAAGCATGCCCTCAGCTTTTAATGAACTTAAATGTAGCACATATGGC TTAATCTCTTAGACTTAGATAAGGGAGTTCAATTCAAAACCATATATGTCAAGACCACAAATAATCAAGAGTTGATTTCAAGATTATAAA TACTCATGATCAGAAAATAGTACTTATTAGCAATTAAAGGGAGGAAAAGAAATTGTTTATACTGAAGAGAATGTTTATGAGGAGTGTGTA TGTACCTGTGGTATACCAAATAGCATACATGTACACACAAAAATGTGTGTATACATTTGGGTTGTGTGTATACATCTTGCCATATACAAT ATACAAACATATGCCCATTCCTGTGATAGCATACAAATTCAAACATACAGAAACACACACAGATATGGACACAGTACAATTCTTCTTTTC AAATGAAGACATTGATAATATTAAATAATTTAATTTTAAGACTGAAACCCTTAATATTGTGTGAAAAAGAGTAATAAAACCTTTGAAAGT AGAGTAGATGATCACATCAAAGTATTTTTGTAAAAGAATTCTAGTGTAGGACTTAATTATTTTTAAAATATATTTCTTCTCTTCTTTCCA TTTTCCCTTCCCTTGTAGTTTTATTATCTTTCTGTCTTTTACACCTGCTCTTTATGTGAAAATGTATATGAATCCTTTTAAAATGATTAG GATTATTGAAATGTATGTCCCGTAAATTTGGTTTTTGGGCAGACTTTCTCTCTAACTGGCTATTCATTCATCCTTCAGGAGGATCTTAGC CAAGAATATTTGCAATGACACATGAATTTAATTTTATAAATATAATGGAAAACAGATTTTTCATCATATCATGAATAAAATATAGAGGTA ACTATGTTGTATTTTCTTGAACCTAGATACTTTCTCATAGTGTTTGCTTAGAATTAACTTTGTCCTATTTGTCAACTGGGTTCTGGAAAA AAACAAACATGATGAAGCTTTTGAATAATTGTGCAGTTTTTTAACTAGGGAAAGCTTTGTACTGCTGCTAATGATATGCACCCAGAAACC TTGTTAGACAAAAGGCAGTTTCAAGCCAATGCTATGGTTTCCATGTGGACATACAGTGCCTATGTAGCAGGCACTTAGAGTAAATGGACT TGCCTTAATTTATAAAGGAGGGAAGAGGTAGAAGGGAACCATGGGTCCTCCAGCTAGAGGGGGAGTTTACTAAAAGGGAGTCCTTGGAAA GGGGAATGGAGAGAAGGTGCCTTTGACTGTCTTCTATCCATTAGTTCTGCCCTGGAGCACACTGGGGAAGCAGGCTGCGGGCCTTCCAAA AGTAAAAAATGGTGATATGCAATCGAAGCTTATCCTTAGCCTATGCACATTTGTCTCAGCTGGGCATTGTCTTTTCAGAGAGCTTGTAGC ACAAGGGCTACACATGGGCGCCAAGATGGTGGTAGATACACCTTGGTGCACTTTTTGTTTTACTTGTTTCTTAAGACTATTTCACAAGTC CTGTGAGGCAAAAAAACAAAACAAAACAAAACAACCAAACAAATACAATCTAACTTTTACCCAATCTACAGCAGGAAATCAAAGGAGTGG GTGGAATGAGAGAAAATATGCAAAGAGATCATTTTTAAGTTTGATTTCCTGTCTGTAATTTTCAAGGACTAATATAGCAAATTTTTCTTC TGCCATTATCATTTATGTCTCCCTATTTACCACACAATAATGTAAATGCAGAGAATGAGGAGGCATCTTTTAAAAGCCTTAGGATATTCT ATATGATGACCTCAATATTGACTTTCAGCCATACTGGGAAAACTTACTTTTCATGGAGTGCCACCTAACAGTGAATGTATTAGAGTATAA AATGTTTGCCATGTATACACCTGTATGTGCACATACACACATTACACACACACACAGAATGCACATTTCACACACATATACTTATTATTC AAGTTGAAACTGCACTCTAATCAATCTGAGTCTATTGCTGTTTCAACTCTTAAAATCAATATCTCCTACATTAGTAGATATAAACATAAT TCAAATATTTAAATATTTAAGAGGAGAAAAGTAACTAGAAAACCAATGAAAAGTGAGGCCATCAGAAATAGAAAATGCCTGGCACGAACA GTCTATCTAAATTCTCAATTTCACTTCAAATTAGAGAATCCATAATGGACTAGAATATAAATTACAAACACATACACACATCTTCACTTA AAGTTGTTTTAAGTTCTTTGAAGTTCTGACATGTTTTTAGCCAGGGTTATTTGTTCAGGTTCTTCCTTGTTAGGATTCCAGACTGGAAAG TTGGAAGTCTCAGGAAATGCATGTTTCCATGAGTTTTTTAGTTTCACAGTTTTACAGATCCAACGACACAATCTTTTAATCTTTGGTCAC TCAACCAAACAGGAGTTCCGTAGGCAGAGTGCTCACTTTGAATTGCTAATAGAAAATAATGCACAGTGTCCTCAGGATATGCTAAACAAG GTTTTTAAGAGCATTTTATTTTACAGCACTTTAGTCTTTTCAGCTAGATTTCAGTGACACTATGGTGTAAATGCTATATCTGCCATAACT TATTGGTGGCTCCTGTGTTACATACAGTTTTAAATAATGCTCTAAATTGTTTGTTTTCCCAATGATAATGATAAAGTGTTCTGTAGAATT TGTAAAACATGTCAATTGAATCTGTTGAAAATTGTGTAATTGTTATTTCAATTGTGATACTATTTTGTAGGTAATAGTTTTAAACGTATA TTTGTATGAGTCAAAAGTATGTGCTTGTATGTGGTATGTGTGTGTAAGTATATAATATCTTATCAAAAATCAAACTTATCCTAAAGAAAA AGGGCACATTGTGACCAGCCTTAATTTATTAACACTTTTTTGTTGTTTTTGCAATTTGGATTTAAAATTGAAACAGAAATTAAGTTTTTG TTAAAAATGGTGTCTTTTAATTTTGTGAGGAATGGGCTTTAGAACCTATCTGAGTTCCCACAAGCAAACTGTCCACCTTGTGAGGTACCC CATTGCTTTTCGTAATAATCAAACATCAATTCATATATTAACTTCATTTTCATACAGACTAATTTGTTTTCATCAACAATAGAACCAGTA CACCTTTAAAGTTGACCTTCCCAACATGGCACCCATTTTTCTTTAATGATAAATTTTCCATGAAAAATTGTTTCTCCAAACCATTACTTT TTAAAATTCAATCTTCCCAAGTAAGATGAACTGCCTTGGTGTTAGGAGAGCTTTTAAAGGCCCATCCATACTAGGTGGTTCCAACATGGT TCTCTTCTCGAGAAAACAAGCATGCAACCCACACACTTTTCTGGTCTGCCCCACGTGTAGAATTAGTCTAGCAATAGAAAACTCATGACT GACAAGGATCTACACATGTGGTCATGCTTGAAGCAAAAATTCTGTGACCTTCTTTGGGCTTGGATCTGATTACAGAATATTAATTAACTT TCTTATTTCCTTTCTTTCTCCATCCTTAGTTATTCCTTTTCAATATTTAGAGTTGCCAGGTAAAATACAGGATATCCAGTGAAATTTAAA TTTCAGATAAACAGTATTTCTTTAGCATATTTCTCATATATTTAATCAGACATACTTTCACTTTAAAAAAAGTTTATCTGAAATTCAAAT GTAACTGGGTATGTCCTATATATTTTTTCCTAAATCTCACAATTCTATCCACACTGCCTTTCTATCTTTTTCAGCTGGGCTATCTATAAG GGGCGAGATCTACCTCCCTCCATACCCTTGTGTTCAGACACCTTATGAATATCTGCAGTCATAATGTCCTTCAAGAAAGAAAACATTGGT CAGCTCTAGGTCCTGCAAATGCTTTTTGAAGGACGAACTCAAATACAGATGGGATAATCAAGTAAATATCTTCATAGGATCAATGCCACC ATGTTCAACACTTCCCTTTGCCAGCCTGTTGTGAGGTCCAAGTTTCCCCATTAATCCCTTATATAGCATTTCCCAGTAACTGGGACAACC AAAAACACACCGACATATTAGAAATGCTCCTGAAAAGTGGCAACACCGCCTAACTCAGTACCAGGACCTCTTTTAAATTCAATTTCTTTT TTCTTTCAGAGAGATAACAAACGAATTCATTATTTCCCCCATTCACATCTTACCACAAATTATTTTTATCAGGTTAAAACTGGTCATCTA CGGAATTGTAGAAAGGTGACATAGGAACTGTCTTCACTGCTGGAAGAATAAAAGAGTCTGAGGTATAGACACTGCCCTGGTGACACCTTC TCAGAACATTGTTGGGGGACAGGGGAGGCAGGCGCAAGTAGGGGATAGAATCTGACCCTGACATGCAGCTATCACCTGGCAGAGAGACTC GTCAAAGCAAATTATAACGACCAGTACTATTTTTTTTTGGAATTGAAAACCCAAGAAGCCCTAAAATAAGAACAGTGAGATCAAAGGCTG GTTTCTAAAACAATGCAGAAAATAGAACCATGTTGGAATTCCTAAATTCTAGCTTTCAAATACTACTGTTTCCAACAGTGAATCCTTGAC AGAGACTGAATGCAGATGGAATTTTGAAACATTTTCAGTAGCTACCTCCTCTCCTGAAATTCCTATAAGTGGCAGAGGAAAATCCAAATC CTTTAATATAACATGTCCATCTCATGACTCCTGCTTACACACATTTGTGTTGATTTGCTTCATTTCTGGAGGATGGGAATTTGCAGAGCT GGTGACATTTCCTTCATTAGACACCAGAAATTCACCAGAGAGAGACAGATCTGTGCCTTCTCTTTTTAGGATCTGGTTATTGATACTTTA ATAAATGTGGTGTAAAGAAAATCCATGGCTACAGTCTGTATAGAAAATGTGAATTTTTTAAATAAGATTGTGTTCTTAATGTAAAAAATA >63686_63686_2_PDE3B-PLCXD3_PDE3B_chr11_14889304_ENST00000282096_PLCXD3_chr5_41313872_ENST00000377801_length(amino acids)=1051AA_BP= MRRDERDAKAMRSLQPPDGAGSPPESLRNGYVKSCVSPLRQDPPRGFFFHLCRFCNVELRPPPASPQQPRRCSPFCRARLSLGALAAFVL ALLLGAEPESWAAGAAWLRTLLSVCSHSLSPLFSIACAFFFLTCFLTRTKRGPGPGRSCGSWWLLALPACCYLGDFLVWQWWSWPWGDGD AGSAAPHTPPEAAAGRLLLVLSCVGLLLTLAHPLRLRHCVLVLLLASFVWWVSFTSLGSLPSALRPLLSGLVGGAGCLLALGLDHFFQIR EAPLHPRLSSAAEEKVPVIRPRRRSSCVSLGETAASYYGSCKIFRRPSLPCISREQMILWDWDLKQWYKPHYQNSGGGNGVDLSVLNEAR NMVSDLLTDPSLPPQVISSLRSISSLMGAFSGSCRPKINPLTPFPGFYPCSEIEDPAEKGDRKLNKGLNRNSLPTPQLRRSSGTSGLLPV EQSSRWDRNNGKRPHQEFGISSQGCYLNGPFNSNLLTIPKQRSSSVSLTHHVGLRRAGVLSSLSPVNSSNHGPVSTGSLTNRSPIEFPDT ADFLNKPSVILQRSLGNAPNTPDFYQQLRNSDSNLCNSCGHQMLKYVSTSESDGTDCCSGKSGEEENIFSKESFKLMETQQEEETEKKDS RKLFQEGDKWLTEEAQSEQQTNIEQEVSLDLILVEEYDSLIEKMSNWNFPIFELVEKMGEKSGRILSQVMYTLFQDTGLLEIFKIPTQQF MNYFRALENGYRDIPYHNRIHATDVLHAVWYLTTRPVPGLQQIHNGCGTGNETDSDGRINHGRIAYISSKSCSNPDESYGCLSSNIPALE LMALYVAAAMHDYDHPGRTNAFLVATNAPQAVLYNDRSVLENHHAASAWNLYLSRPEYNFLLHLDHVEFKRFRFLVIEAILATDLKKHFD FLAEFNAKANDVNSNGIEWSNENDRLLVCQVCIKLADINGPAKVRDLHLKWTEGIVNEFYEQGDEEANLGLPISPFMDRSSPQLAKLQES -------------------------------------------------------------- >63686_63686_3_PDE3B-PLCXD3_PDE3B_chr11_14889304_ENST00000455098_PLCXD3_chr5_41313872_ENST00000328457_length(transcript)=9855nt_BP=3231nt GAGGCGGCAGCTAAACTGGTCCTGGAGAGAAGCCCCTTCCGCCCCTCTCCTCAGCCAGCATGTCCCGGACTCCGCCGCTCCTCAGTCCGC GCGGTGGGGACCCCGGGCCGTGGCGGCCGGCGCAGCCCTGACGGGTTGCGAACCAGGGGGCGCCCCGAACGCGGGGGTTGGGGTCTGGGA GCGCGAGCGGCCGCTACGGTACGAGCGGGGTGTGCTGAGTCCCGTGGCCACCCCCGGCCCCAGCCATGAGGAGGGACGAGCGAGACGCCA AAGCCATGCGGTCCCTGCAGCCGCCGGATGGGGCCGGCTCGCCCCCCGAGAGTCTGAGGAACGGCTACGTGAAGAGCTGCGTGAGCCCCT TGCGGCAGGACCCTCCGCGCGGCTTCTTCTTCCACCTCTGCCGCTTCTGCAACGTGGAGCTGCGGCCGCCGCCGGCCTCTCCCCAGCAGC CGCGGCGCTGCTCCCCCTTCTGCCGGGCGCGCCTCTCGCTGGGCGCCCTGGCTGCCTTTGTCCTCGCCCTGCTGCTGGGCGCGGAACCCG AGAGCTGGGCTGCCGGGGCCGCCTGGCTGCGGACGCTGCTGAGCGTGTGTTCGCACAGCTTGAGCCCCCTCTTCAGCATCGCCTGTGCCT TCTTCTTCCTCACCTGCTTCCTCACCCGGACCAAGCGGGGACCCGGCCCGGGCCGGAGCTGCGGCTCCTGGTGGCTGCTGGCGCTGCCCG CCTGCTGTTACCTGGGGGACTTCTTGGTGTGGCAGTGGTGGTCTTGGCCTTGGGGGGATGGCGACGCAGGGTCCGCGGCCCCGCACACGC CCCCGGAGGCGGCAGCGGGCAGGTTGCTGCTGGTGCTGAGCTGCGTAGGGCTGCTGCTGACGCTCGCGCACCCGCTGCGGCTCCGGCACT GCGTTCTGGTGCTGCTCCTGGCCAGCTTCGTCTGGTGGGTCTCCTTCACCAGCCTCGGGTCGCTGCCCTCCGCCCTCAGGCCGCTGCTCT CCGGCCTGGTGGGGGGCGCTGGCTGCCTGCTGGCCCTGGGGTTGGATCACTTCTTTCAAATCAGGGAAGCGCCTCTTCATCCTCGACTGT CCAGTGCCGCCGAAGAAAAAGTGCCTGTGATCCGACCCCGGAGGAGGTCCAGCTGCGTGTCGTTAGGAGAAACTGCAGCCAGTTACTATG GCAGTTGCAAAATATTCAGGAGACCGTCGTTGCCTTGTATTTCCAGAGAACAGATGATTCTTTGGGATTGGGACTTAAAACAATGGTATA AGCCTCATTATCAAAATTCTGGAGGTGGAAATGGAGTTGATCTTTCAGTGCTAAATGAGGCTCGCAATATGGTGTCAGATCTTCTGACTG ATCCAAGCCTTCCACCACAAGGACTAAATAGGAATAGTTTGCCAACTCCACAGCTGAGGAGAAGCTCAGGAACTTCAGGATTGCTACCTG TTGAACAGTCTTCAAGGTGGGATCGTAATAATGGCAAAAGACCTCACCAAGAATTTGGCATTTCAAGTCAAGGATGCTATCTAAATGGGC CTTTTAATTCAAATCTACTGACTATCCCGAAGCAAAGGTCATCTTCTGTATCACTGACTCACCATGTAGGTCTCAGAAGAGCTGGTGTTT TGTCCAGTCTGAGTCCTGTGAATTCTTCCAACCATGGACCAGTGTCTACTGGCTCTCTAACTAATCGATCACCCATAGAATTTCCTGATA CTGCTGATTTTCTTAATAAGCCAAGCGTTATCTTGCAGAGATCTCTGGGCAATGCACCTAATACTCCAGATTTTTATCAGCAACTTAGAA ATTCTGATAGCAATCTGTGTAACAGCTGTGGACATCAAATGCTGAAATATGTTTCAACATCTGAATCAGATGGTACAGATTGCTGCAGTG GAAAATCAGGTGAAGAAGAAAACATTTTCTCGAAAGAATCATTCAAACTTATGGAAACTCAACAAGAAGAGGAAACAGAGAAGAAAGACA GCAGAAAATTATTTCAGGAAGGTGATAAGTGGCTAACAGAAGAGGCACAGAGTGAACAGCAAACAAATATTGAACAGGAAGTATCACTGG ACCTGATTTTAGTAGAAGAGTATGACTCATTAATAGAAAAGATGAGCAACTGGAATTTTCCAATTTTTGAACTTGTAGAAAAGATGGGAG AGAAATCAGGAAGGATTCTCAGTCAGGTTATGTATACCTTATTTCAAGACACTGGTTTATTGGAAATATTTAAAATTCCCACTCAACAAT TTATGAACTATTTTCGTGCATTAGAAAATGGCTATCGAGACATTCCTTATCACAATCGTATACATGCCACAGATGTGCTACATGCAGTTT GGTATCTGACAACACGGCCAGTTCCTGGCTTACAGCAGATCCACAATGGTTGTGGAACAGGAAATGAAACAGATTCTGATGGTAGAATTA ACCATGGGCGAATTGCTTATATTTCTTCGAAGAGCTGCTCTAATCCTGATGAGAGTTATGGCTGCCTGTCTTCAAACATTCCTGCATTAG AATTGATGGCTCTATACGTGGCAGCTGCCATGCATGATTATGATCACCCAGGGAGGACAAATGCATTTCTAGTGGCTACAAATGCCCCTC AGGCAGTTTTATACAATGACAGATCTGTTCTGGAAAATCATCATGCTGCGTCAGCTTGGAATCTATATCTTTCTCGCCCAGAATACAACT TCCTTCTTCATCTTGATCATGTGGAATTCAAGCGCTTTCGTTTTTTAGTCATTGAAGCAATCCTTGCTACGGATCTTAAAAAGCATTTTG ATTTTCTCGCAGAATTCAATGCCAAGGCAAATGATGTAAATAGTAATGGCATAGAATGGAGTAATGAAAATGATCGCCTCTTGGTATGCC AGGTGTGCATCAAACTGGCAGATATAAATGGCCCAGCAAAAGTTCGAGACTTGCATTTGAAATGGACAGAAGGCATTGTCAATGAATTTT ATGAGCAGGGAGATGAAGAAGCAAATCTTGGTCTGCCCATCAGTCCATTCATGGATCGTTCTTCTCCTCAACTAGCAAAACTCCAAGAAT CTTTTATCACCCACATAGTGGGTCCCCTGTGTAACTCCTATGATGCTGCTGGTTTGCTACCAGGTCAGTGGTTAGAAGCAGAAGAGGATA ATGATACTGAAAGTGGTGATGATGAAGACGGTGAAGAATTAGATACAGAAGATGAAGAAATGGAAAACAATCTAAATCCAAAGCTCTTCC TGCCATGATGCAGTGGGTCCGCACGCAGAAGCCAGGAGAGAGTGGCATCAATATTGTCACTGCCGATTTTGTAGAACTTGGTGACTTTAT CAGCACTGTCATAAAGCTCAACTATGTCTTTGATGAAGGAGAAGCCAACACTTGATAGCACTACTTGGAGTTTCCATGAATAAGATGGAG AAAGCTCATTGTATTAGGGCATACTATCTGTAAACACTCTGATCTTCCTATTCCACTGAGTCTCTGAAGGGAATAGGGCTGGTAGTGGGT GGGAAAAGGGGAAAAACTGTTTCTTCAGTGATTACAATCATACTCTTCATTACTATAAATATTTCATTTCCCATTTGATGAGCAAAATCT ACTTCTAGTGTTAGGAATAAAAAAAAAAGACCAGTAACTTTGTTTTTCAAAATTAGTCTTTGTAACATAGAATTCATGAGTGTTTACTTG ATTAGGTTCTCTATTTCCAGCCTATGACTCCTACGCTGTCTATACCCTGCAACCTTTCTGCTCCCTCTCTTGCTCGCTCTTTTTAATCAG ATGCTGTATGGGAATCAAAACAATTGAATGCCCAACATTTTGTGTATTACATTGTTGTCTTAAAACTTACTAGTTTTGTGGGACTTGTTA TAATGCTCTATAGTCATCCACAGTTGGGCAATCATAGCTAATTTTTGGTCATAGAAAATCTGCATCAAATCAGTTTCCATGCATCAGTAA TATTGAAGGTCATAATCAGTGATTTTTGTTATATGAAAATAATAGTGTTTCACAGTATTTCTATTTAAGGCAGCTATAAATATAGGAGAA AAATGTTTTTGGAGAGCTGTGAATGCCAATTTCAGAGGGAAAAATGGTTGAGGGGTGAAAGAGATGTATGGCATTTTAATTTGGCAATCT CTTAAATAATATTGCCCTGCAAGTACCCAGTAAATGGTAAGGTACAAGTGTGTTAAAATTGAAAACTCTGAAAATAACTCTTTAAAAAGC CCTCTTAATGATGCTCTTGATGAAAGAAAAAGACAGAAGGAAGGAAGAAGAAAAAGACTGCAAGCTTTCCTGCCAATTTGGGATTTTCAA ATATTTAATTCTAAATTCCAGATTTTAAGGAAGATTTTTCAAGAAACTGCAAGTTTTTGACTTGAAGGAAAGAAAGAGGAAGGCTGGTAG AAGCAGTTAGAGCAATGTGTTTGAAATTATGTCCATGAAATCACAGGGATCTCTGAAATATCTTTAGGAAACTTGAAATTTATGAGGTCT GAATGGACTTGTTTAAAATTGGCTCTGACTCCTCACTTCTGAGTTTCATCCTATCCGAGGGATGAGATTAAGGCAGAGGCAAAAGTTTCA CACAAAGTTTCTGCAACCTAACGTTTAATAGTCCGGGTCTACAGGGAAGAACAATGACACAGCTTGAGCGTTACTTCCTCCTTCGTGTCA TTGTGATATTTGACAACTCTAAAAAATAAAAAAAAAAAACTTAGAGCACAATAATCCTTGCCTATGTACTTCACAGGAATATTGTGAGGT GTTTATAAAATTATAAAATTTGATGAAATTCTTACAATTATTAATTATTTTATTTTCATGTTTAGAAATAATCACACCCCAATAGTTTCC TAGGATAATACAGTCCATGCAAAGTAGGGTCATAGAGAAATAAAAGCATGCCCTCAGCTTTTAATGAACTTAAATGTAGCACATATGGCT TAATCTCTTAGACTTAGATAAGGGAGTTCAATTCAAAACCATATATGTCAAGACCACAAATAATCAAGAGTTGATTTCAAGATTATAAAT ACTCATGATCAGAAAATAGTACTTATTAGCAATTAAAGGGAGGAAAAGAAATTGTTTATACTGAAGAGAATGTTTATGAGGAGTGTGTAT GTACCTGTGGTATACCAAATAGCATACATGTACACACAAAAATGTGTGTATACATTTGGGTTGTGTGTATACATCTTGCCATATACAATA TACAAACATATGCCCATTCCTGTGATAGCATACAAATTCAAACATACAGAAACACACACAGATATGGACACAGTACAATTCTTCTTTTCA AATGAAGACATTGATAATATTAAATAATTTAATTTTAAGACTGAAACCCTTAATATTGTGTGAAAAAGAGTAATAAAACCTTTGAAAGTA GAGTAGATGATCACATCAAAGTATTTTTGTAAAAGAATTCTAGTGTAGGACTTAATTATTTTTAAAATATATTTCTTCTCTTCTTTCCAT TTTCCCTTCCCTTGTAGTTTTATTATCTTTCTGTCTTTTACACCTGCTCTTTATGTGAAAATGTATATGAATCCTTTTAAAATGATTAGG ATTATTGAAATGTATGTCCCGTAAATTTGGTTTTTGGGCAGACTTTCTCTCTAACTGGCTATTCATTCATCCTTCAGGAGGATCTTAGCC AAGAATATTTGCAATGACACATGAATTTAATTTTATAAATATAATGGAAAACAGATTTTTCATCATATCATGAATAAAATATAGAGGTAA CTATGTTGTATTTTCTTGAACCTAGATACTTTCTCATAGTGTTTGCTTAGAATTAACTTTGTCCTATTTGTCAACTGGGTTCTGGAAAAA AACAAACATGATGAAGCTTTTGAATAATTGTGCAGTTTTTTAACTAGGGAAAGCTTTGTACTGCTGCTAATGATATGCACCCAGAAACCT TGTTAGACAAAAGGCAGTTTCAAGCCAATGCTATGGTTTCCATGTGGACATACAGTGCCTATGTAGCAGGCACTTAGAGTAAATGGACTT GCCTTAATTTATAAAGGAGGGAAGAGGTAGAAGGGAACCATGGGTCCTCCAGCTAGAGGGGGAGTTTACTAAAAGGGAGTCCTTGGAAAG GGGAATGGAGAGAAGGTGCCTTTGACTGTCTTCTATCCATTAGTTCTGCCCTGGAGCACACTGGGGAAGCAGGCTGCGGGCCTTCCAAAA GTAAAAAATGGTGATATGCAATCGAAGCTTATCCTTAGCCTATGCACATTTGTCTCAGCTGGGCATTGTCTTTTCAGAGAGCTTGTAGCA CAAGGGCTACACATGGGCGCCAAGATGGTGGTAGATACACCTTGGTGCACTTTTTGTTTTACTTGTTTCTTAAGACTATTTCACAAGTCC TGTGAGGCAAAAAAACAAAACAAAACAAAACAACCAAACAAATACAATCTAACTTTTACCCAATCTACAGCAGGAAATCAAAGGAGTGGG TGGAATGAGAGAAAATATGCAAAGAGATCATTTTTAAGTTTGATTTCCTGTCTGTAATTTTCAAGGACTAATATAGCAAATTTTTCTTCT GCCATTATCATTTATGTCTCCCTATTTACCACACAATAATGTAAATGCAGAGAATGAGGAGGCATCTTTTAAAAGCCTTAGGATATTCTA TATGATGACCTCAATATTGACTTTCAGCCATACTGGGAAAACTTACTTTTCATGGAGTGCCACCTAACAGTGAATGTATTAGAGTATAAA ATGTTTGCCATGTATACACCTGTATGTGCACATACACACATTACACACACACACAGAATGCACATTTCACACACATATACTTATTATTCA AGTTGAAACTGCACTCTAATCAATCTGAGTCTATTGCTGTTTCAACTCTTAAAATCAATATCTCCTACATTAGTAGATATAAACATAATT CAAATATTTAAATATTTAAGAGGAGAAAAGTAACTAGAAAACCAATGAAAAGTGAGGCCATCAGAAATAGAAAATGCCTGGCACGAACAG TCTATCTAAATTCTCAATTTCACTTCAAATTAGAGAATCCATAATGGACTAGAATATAAATTACAAACACATACACACATCTTCACTTAA AGTTGTTTTAAGTTCTTTGAAGTTCTGACATGTTTTTAGCCAGGGTTATTTGTTCAGGTTCTTCCTTGTTAGGATTCCAGACTGGAAAGT TGGAAGTCTCAGGAAATGCATGTTTCCATGAGTTTTTTAGTTTCACAGTTTTACAGATCCAACGACACAATCTTTTAATCTTTGGTCACT CAACCAAACAGGAGTTCCGTAGGCAGAGTGCTCACTTTGAATTGCTAATAGAAAATAATGCACAGTGTCCTCAGGATATGCTAAACAAGG TTTTTAAGAGCATTTTATTTTACAGCACTTTAGTCTTTTCAGCTAGATTTCAGTGACACTATGGTGTAAATGCTATATCTGCCATAACTT ATTGGTGGCTCCTGTGTTACATACAGTTTTAAATAATGCTCTAAATTGTTTGTTTTCCCAATGATAATGATAAAGTGTTCTGTAGAATTT GTAAAACATGTCAATTGAATCTGTTGAAAATTGTGTAATTGTTATTTCAATTGTGATACTATTTTGTAGGTAATAGTTTTAAACGTATAT TTGTATGAGTCAAAAGTATGTGCTTGTATGTGGTATGTGTGTGTAAGTATATAATATCTTATCAAAAATCAAACTTATCCTAAAGAAAAA GGGCACATTGTGACCAGCCTTAATTTATTAACACTTTTTTGTTGTTTTTGCAATTTGGATTTAAAATTGAAACAGAAATTAAGTTTTTGT TAAAAATGGTGTCTTTTAATTTTGTGAGGAATGGGCTTTAGAACCTATCTGAGTTCCCACAAGCAAACTGTCCACCTTGTGAGGTACCCC ATTGCTTTTCGTAATAATCAAACATCAATTCATATATTAACTTCATTTTCATACAGACTAATTTGTTTTCATCAACAATAGAACCAGTAC ACCTTTAAAGTTGACCTTCCCAACATGGCACCCATTTTTCTTTAATGATAAATTTTCCATGAAAAATTGTTTCTCCAAACCATTACTTTT TAAAATTCAATCTTCCCAAGTAAGATGAACTGCCTTGGTGTTAGGAGAGCTTTTAAAGGCCCATCCATACTAGGTGGTTCCAACATGGTT CTCTTCTCGAGAAAACAAGCATGCAACCCACACACTTTTCTGGTCTGCCCCACGTGTAGAATTAGTCTAGCAATAGAAAACTCATGACTG ACAAGGATCTACACATGTGGTCATGCTTGAAGCAAAAATTCTGTGACCTTCTTTGGGCTTGGATCTGATTACAGAATATTAATTAACTTT CTTATTTCCTTTCTTTCTCCATCCTTAGTTATTCCTTTTCAATATTTAGAGTTGCCAGGTAAAATACAGGATATCCAGTGAAATTTAAAT TTCAGATAAACAGTATTTCTTTAGCATATTTCTCATATATTTAATCAGACATACTTTCACTTTAAAAAAAGTTTATCTGAAATTCAAATG TAACTGGGTATGTCCTATATATTTTTTCCTAAATCTCACAATTCTATCCACACTGCCTTTCTATCTTTTTCAGCTGGGCTATCTATAAGG GGCGAGATCTACCTCCCTCCATACCCTTGTGTTCAGACACCTTATGAATATCTGCAGTCATAATGTCCTTCAAGAAAGAAAACATTGGTC AGCTCTAGGTCCTGCAAATGCTTTTTGAAGGACGAACTCAAATACAGATGGGATAATCAAGTAAATATCTTCATAGGATCAATGCCACCA TGTTCAACACTTCCCTTTGCCAGCCTGTTGTGAGGTCCAAGTTTCCCCATTAATCCCTTATATAGCATTTCCCAGTAACTGGGACAACCA AAAACACACCGACATATTAGAAATGCTCCTGAAAAGTGGCAACACCGCCTAACTCAGTACCAGGACCTCTTTTAAATTCAATTTCTTTTT TCTTTCAGAGAGATAACAAACGAATTCATTATTTCCCCCATTCACATCTTACCACAAATTATTTTTATCAGGTTAAAACTGGTCATCTAC GGAATTGTAGAAAGGTGACATAGGAACTGTCTTCACTGCTGGAAGAATAAAAGAGTCTGAGGTATAGACACTGCCCTGGTGACACCTTCT CAGAACATTGTTGGGGGACAGGGGAGGCAGGCGCAAGTAGGGGATAGAATCTGACCCTGACATGCAGCTATCACCTGGCAGAGAGACTCG TCAAAGCAAATTATAACGACCAGTACTATTTTTTTTTGGAATTGAAAACCCAAGAAGCCCTAAAATAAGAACAGTGAGATCAAAGGCTGG TTTCTAAAACAATGCAGAAAATAGAACCATGTTGGAATTCCTAAATTCTAGCTTTCAAATACTACTGTTTCCAACAGTGAATCCTTGACA GAGACTGAATGCAGATGGAATTTTGAAACATTTTCAGTAGCTACCTCCTCTCCTGAAATTCCTATAAGTGGCAGAGGAAAATCCAAATCC TTTAATATAACATGTCCATCTCATGACTCCTGCTTACACACATTTGTGTTGATTTGCTTCATTTCTGGAGGATGGGAATTTGCAGAGCTG GTGACATTTCCTTCATTAGACACCAGAAATTCACCAGAGAGAGACAGATCTGTGCCTTCTCTTTTTAGGATCTGGTTATTGATACTTTAA TAAATGTGGTGTAAAGAAAATCCATGGCTACAGTCTGTATAGAAAATGTGAATTTTTTAAATAAGATTGTGTTCTTAATGTAAAAAATAA >63686_63686_3_PDE3B-PLCXD3_PDE3B_chr11_14889304_ENST00000455098_PLCXD3_chr5_41313872_ENST00000328457_length(amino acids)=1000AA_BP= MRRDERDAKAMRSLQPPDGAGSPPESLRNGYVKSCVSPLRQDPPRGFFFHLCRFCNVELRPPPASPQQPRRCSPFCRARLSLGALAAFVL ALLLGAEPESWAAGAAWLRTLLSVCSHSLSPLFSIACAFFFLTCFLTRTKRGPGPGRSCGSWWLLALPACCYLGDFLVWQWWSWPWGDGD AGSAAPHTPPEAAAGRLLLVLSCVGLLLTLAHPLRLRHCVLVLLLASFVWWVSFTSLGSLPSALRPLLSGLVGGAGCLLALGLDHFFQIR EAPLHPRLSSAAEEKVPVIRPRRRSSCVSLGETAASYYGSCKIFRRPSLPCISREQMILWDWDLKQWYKPHYQNSGGGNGVDLSVLNEAR NMVSDLLTDPSLPPQGLNRNSLPTPQLRRSSGTSGLLPVEQSSRWDRNNGKRPHQEFGISSQGCYLNGPFNSNLLTIPKQRSSSVSLTHH VGLRRAGVLSSLSPVNSSNHGPVSTGSLTNRSPIEFPDTADFLNKPSVILQRSLGNAPNTPDFYQQLRNSDSNLCNSCGHQMLKYVSTSE SDGTDCCSGKSGEEENIFSKESFKLMETQQEEETEKKDSRKLFQEGDKWLTEEAQSEQQTNIEQEVSLDLILVEEYDSLIEKMSNWNFPI FELVEKMGEKSGRILSQVMYTLFQDTGLLEIFKIPTQQFMNYFRALENGYRDIPYHNRIHATDVLHAVWYLTTRPVPGLQQIHNGCGTGN ETDSDGRINHGRIAYISSKSCSNPDESYGCLSSNIPALELMALYVAAAMHDYDHPGRTNAFLVATNAPQAVLYNDRSVLENHHAASAWNL YLSRPEYNFLLHLDHVEFKRFRFLVIEAILATDLKKHFDFLAEFNAKANDVNSNGIEWSNENDRLLVCQVCIKLADINGPAKVRDLHLKW TEGIVNEFYEQGDEEANLGLPISPFMDRSSPQLAKLQESFITHIVGPLCNSYDAAGLLPGQWLEAEEDNDTESGDDEDGEELDTEDEEME -------------------------------------------------------------- >63686_63686_4_PDE3B-PLCXD3_PDE3B_chr11_14889304_ENST00000455098_PLCXD3_chr5_41313872_ENST00000377801_length(transcript)=10048nt_BP=3231nt GAGGCGGCAGCTAAACTGGTCCTGGAGAGAAGCCCCTTCCGCCCCTCTCCTCAGCCAGCATGTCCCGGACTCCGCCGCTCCTCAGTCCGC GCGGTGGGGACCCCGGGCCGTGGCGGCCGGCGCAGCCCTGACGGGTTGCGAACCAGGGGGCGCCCCGAACGCGGGGGTTGGGGTCTGGGA GCGCGAGCGGCCGCTACGGTACGAGCGGGGTGTGCTGAGTCCCGTGGCCACCCCCGGCCCCAGCCATGAGGAGGGACGAGCGAGACGCCA AAGCCATGCGGTCCCTGCAGCCGCCGGATGGGGCCGGCTCGCCCCCCGAGAGTCTGAGGAACGGCTACGTGAAGAGCTGCGTGAGCCCCT TGCGGCAGGACCCTCCGCGCGGCTTCTTCTTCCACCTCTGCCGCTTCTGCAACGTGGAGCTGCGGCCGCCGCCGGCCTCTCCCCAGCAGC CGCGGCGCTGCTCCCCCTTCTGCCGGGCGCGCCTCTCGCTGGGCGCCCTGGCTGCCTTTGTCCTCGCCCTGCTGCTGGGCGCGGAACCCG AGAGCTGGGCTGCCGGGGCCGCCTGGCTGCGGACGCTGCTGAGCGTGTGTTCGCACAGCTTGAGCCCCCTCTTCAGCATCGCCTGTGCCT TCTTCTTCCTCACCTGCTTCCTCACCCGGACCAAGCGGGGACCCGGCCCGGGCCGGAGCTGCGGCTCCTGGTGGCTGCTGGCGCTGCCCG CCTGCTGTTACCTGGGGGACTTCTTGGTGTGGCAGTGGTGGTCTTGGCCTTGGGGGGATGGCGACGCAGGGTCCGCGGCCCCGCACACGC CCCCGGAGGCGGCAGCGGGCAGGTTGCTGCTGGTGCTGAGCTGCGTAGGGCTGCTGCTGACGCTCGCGCACCCGCTGCGGCTCCGGCACT GCGTTCTGGTGCTGCTCCTGGCCAGCTTCGTCTGGTGGGTCTCCTTCACCAGCCTCGGGTCGCTGCCCTCCGCCCTCAGGCCGCTGCTCT CCGGCCTGGTGGGGGGCGCTGGCTGCCTGCTGGCCCTGGGGTTGGATCACTTCTTTCAAATCAGGGAAGCGCCTCTTCATCCTCGACTGT CCAGTGCCGCCGAAGAAAAAGTGCCTGTGATCCGACCCCGGAGGAGGTCCAGCTGCGTGTCGTTAGGAGAAACTGCAGCCAGTTACTATG GCAGTTGCAAAATATTCAGGAGACCGTCGTTGCCTTGTATTTCCAGAGAACAGATGATTCTTTGGGATTGGGACTTAAAACAATGGTATA AGCCTCATTATCAAAATTCTGGAGGTGGAAATGGAGTTGATCTTTCAGTGCTAAATGAGGCTCGCAATATGGTGTCAGATCTTCTGACTG ATCCAAGCCTTCCACCACAAGGACTAAATAGGAATAGTTTGCCAACTCCACAGCTGAGGAGAAGCTCAGGAACTTCAGGATTGCTACCTG TTGAACAGTCTTCAAGGTGGGATCGTAATAATGGCAAAAGACCTCACCAAGAATTTGGCATTTCAAGTCAAGGATGCTATCTAAATGGGC CTTTTAATTCAAATCTACTGACTATCCCGAAGCAAAGGTCATCTTCTGTATCACTGACTCACCATGTAGGTCTCAGAAGAGCTGGTGTTT TGTCCAGTCTGAGTCCTGTGAATTCTTCCAACCATGGACCAGTGTCTACTGGCTCTCTAACTAATCGATCACCCATAGAATTTCCTGATA CTGCTGATTTTCTTAATAAGCCAAGCGTTATCTTGCAGAGATCTCTGGGCAATGCACCTAATACTCCAGATTTTTATCAGCAACTTAGAA ATTCTGATAGCAATCTGTGTAACAGCTGTGGACATCAAATGCTGAAATATGTTTCAACATCTGAATCAGATGGTACAGATTGCTGCAGTG GAAAATCAGGTGAAGAAGAAAACATTTTCTCGAAAGAATCATTCAAACTTATGGAAACTCAACAAGAAGAGGAAACAGAGAAGAAAGACA GCAGAAAATTATTTCAGGAAGGTGATAAGTGGCTAACAGAAGAGGCACAGAGTGAACAGCAAACAAATATTGAACAGGAAGTATCACTGG ACCTGATTTTAGTAGAAGAGTATGACTCATTAATAGAAAAGATGAGCAACTGGAATTTTCCAATTTTTGAACTTGTAGAAAAGATGGGAG AGAAATCAGGAAGGATTCTCAGTCAGGTTATGTATACCTTATTTCAAGACACTGGTTTATTGGAAATATTTAAAATTCCCACTCAACAAT TTATGAACTATTTTCGTGCATTAGAAAATGGCTATCGAGACATTCCTTATCACAATCGTATACATGCCACAGATGTGCTACATGCAGTTT GGTATCTGACAACACGGCCAGTTCCTGGCTTACAGCAGATCCACAATGGTTGTGGAACAGGAAATGAAACAGATTCTGATGGTAGAATTA ACCATGGGCGAATTGCTTATATTTCTTCGAAGAGCTGCTCTAATCCTGATGAGAGTTATGGCTGCCTGTCTTCAAACATTCCTGCATTAG AATTGATGGCTCTATACGTGGCAGCTGCCATGCATGATTATGATCACCCAGGGAGGACAAATGCATTTCTAGTGGCTACAAATGCCCCTC AGGCAGTTTTATACAATGACAGATCTGTTCTGGAAAATCATCATGCTGCGTCAGCTTGGAATCTATATCTTTCTCGCCCAGAATACAACT TCCTTCTTCATCTTGATCATGTGGAATTCAAGCGCTTTCGTTTTTTAGTCATTGAAGCAATCCTTGCTACGGATCTTAAAAAGCATTTTG ATTTTCTCGCAGAATTCAATGCCAAGGCAAATGATGTAAATAGTAATGGCATAGAATGGAGTAATGAAAATGATCGCCTCTTGGTATGCC AGGTGTGCATCAAACTGGCAGATATAAATGGCCCAGCAAAAGTTCGAGACTTGCATTTGAAATGGACAGAAGGCATTGTCAATGAATTTT ATGAGCAGGGAGATGAAGAAGCAAATCTTGGTCTGCCCATCAGTCCATTCATGGATCGTTCTTCTCCTCAACTAGCAAAACTCCAAGAAT CTTTTATCACCCACATAGTGGGTCCCCTGTGTAACTCCTATGATGCTGCTGGTTTGCTACCAGGTCAGTGGTTAGAAGCAGAAGAGGATA ATGATACTGAAAGTGGTGATGATGAAGACGGTGAAGAATTAGATACAGAAGATGAAGAAATGGAAAACAATCTAAATCCAAAGCTCTTCC TGCCATGATGCAGTGGGTCCGCACGCAGAAGCCAGGAGAGAGTGGCATCAATATTGTCACTGCCGATTTTGTAGAACTTGGTGACTTTAT CAGCACTGTCATAAAGCTCAACTATGTCTTTGATGAAGGAGAAGCCAACACTTGATAGCACTACTTGGAGTTTCCATGAATAAGATGGAG AAAGCTCATTGTATTAGGGCATACTATCTGTAAACACTCTGATCTTCCTATTCCACTGAGTCTCTGAAGGGAATAGGGCTGGTAGTGGGT GGGAAAAGGGGAAAAACTGTTTCTTCAGTGATTACAATCATACTCTTCATTACTATAAATATTTCATTTCCCATTTGATGAGCAAAATCT ACTTCTAGTGTTAGGAATAAAAAAAAAAGACCAGTAACTTTGTTTTTCAAAATTAGTCTTTGTAACATAGAATTCATGAGTGTTTACTTG ATTAGGTTCTCTATTTCCAGCCTATGACTCCTACGCTGTCTATACCCTGCAACCTTTCTGCTCCCTCTCTTGCTCGCTCTTTTTAATCAG ATGCTGTATGGGAATCAAAACAATTGAATGCCCAACATTTTGTGTATTACATTGTTGTCTTAAAACTTACTAGTTTTGTGGGACTTGTTA TAATGCTCTATAGTCATCCACAGTTGGGCAATCATAGCTAATTTTTGGTCATAGAAAATCTGCATCAAATCAGTTTCCATGCATCAGTAA TATTGAAGGTCATAATCAGTGATTTTTGTTATATGAAAATAATAGTGTTTCACAGTATTTCTATTTAAGGCAGCTATAAATATAGGAGAA AAATGTTTTTGGAGAGCTGTGAATGCCAATTTCAGAGGGAAAAATGGTTGAGGGGTGAAAGAGATGTATGGCATTTTAATTTGGCAATCT CTTAAATAATATTGCCCTGCAAGTACCCAGTAAATGGTAAGGTACAAGTGTGTTAAAATTGAAAACTCTGAAAATAACTCTTTAAAAAGC CCTCTTAATGATGCTCTTGATGAAAGAAAAAGACAGAAGGAAGGAAGGAAGGAAGGAAGGAAGGAAGGAAGGAAGGAAGGAAGGAAAGGA AGAAAGGAAGGGAGGGAGGAAGGGAGGGAAGAAGGGAGGGAAGGACAGAAGGAAGGACGGGAGGAAGGAAGGAAGGGAGGAAGGAAGGAA GGAAGAGAGGGAGGGAGGGAGGAAGAGAGGGAGGGAGGGAGGAAGAGAGGAAGGAAGAAGAAAAAGACTGCAAGCTTTCCTGCCAATTTG GGATTTTCAAATATTTAATTCTAAATTCCAGATTTTAAGGAAGATTTTTCAAGAAACTGCAAGTTTTTGACTTGAAGGAAAGAAAGAGGA AGGCTGGTAGAAGCAGTTAGAGCAATGTGTTTGAAATTATGTCCATGAAATCACAGGGATCTCTGAAATATCTTTAGGAAACTTGAAATT TATGAGGTCTGAATGGACTTGTTTAAAATTGGCTCTGACTCCTCACTTCTGAGTTTCATCCTATCCGAGGGATGAGATTAAGGCAGAGGC AAAAGTTTCACACAAAGTTTCTGCAACCTAACGTTTAATAGTCCGGGTCTACAGGGAAGAACAATGACACAGCTTGAGCGTTACTTCCTC CTTCGTGTCATTGTGATATTTGACAACTCTAAAAAATAAAAAAAAAAAACTTAGAGCACAATAATCCTTGCCTATGTACTTCACAGGAAT ATTGTGAGGTGTTTATAAAATTATAAAATTTGATGAAATTCTTACAATTATTAATTATTTTATTTTCATGTTTAGAAATAATCACACCCC AATAGTTTCCTAGGATAATACAGTCCATGCAAAGTAGGGTCATAGAGAAATAAAAGCATGCCCTCAGCTTTTAATGAACTTAAATGTAGC ACATATGGCTTAATCTCTTAGACTTAGATAAGGGAGTTCAATTCAAAACCATATATGTCAAGACCACAAATAATCAAGAGTTGATTTCAA GATTATAAATACTCATGATCAGAAAATAGTACTTATTAGCAATTAAAGGGAGGAAAAGAAATTGTTTATACTGAAGAGAATGTTTATGAG GAGTGTGTATGTACCTGTGGTATACCAAATAGCATACATGTACACACAAAAATGTGTGTATACATTTGGGTTGTGTGTATACATCTTGCC ATATACAATATACAAACATATGCCCATTCCTGTGATAGCATACAAATTCAAACATACAGAAACACACACAGATATGGACACAGTACAATT CTTCTTTTCAAATGAAGACATTGATAATATTAAATAATTTAATTTTAAGACTGAAACCCTTAATATTGTGTGAAAAAGAGTAATAAAACC TTTGAAAGTAGAGTAGATGATCACATCAAAGTATTTTTGTAAAAGAATTCTAGTGTAGGACTTAATTATTTTTAAAATATATTTCTTCTC TTCTTTCCATTTTCCCTTCCCTTGTAGTTTTATTATCTTTCTGTCTTTTACACCTGCTCTTTATGTGAAAATGTATATGAATCCTTTTAA AATGATTAGGATTATTGAAATGTATGTCCCGTAAATTTGGTTTTTGGGCAGACTTTCTCTCTAACTGGCTATTCATTCATCCTTCAGGAG GATCTTAGCCAAGAATATTTGCAATGACACATGAATTTAATTTTATAAATATAATGGAAAACAGATTTTTCATCATATCATGAATAAAAT ATAGAGGTAACTATGTTGTATTTTCTTGAACCTAGATACTTTCTCATAGTGTTTGCTTAGAATTAACTTTGTCCTATTTGTCAACTGGGT TCTGGAAAAAAACAAACATGATGAAGCTTTTGAATAATTGTGCAGTTTTTTAACTAGGGAAAGCTTTGTACTGCTGCTAATGATATGCAC CCAGAAACCTTGTTAGACAAAAGGCAGTTTCAAGCCAATGCTATGGTTTCCATGTGGACATACAGTGCCTATGTAGCAGGCACTTAGAGT AAATGGACTTGCCTTAATTTATAAAGGAGGGAAGAGGTAGAAGGGAACCATGGGTCCTCCAGCTAGAGGGGGAGTTTACTAAAAGGGAGT CCTTGGAAAGGGGAATGGAGAGAAGGTGCCTTTGACTGTCTTCTATCCATTAGTTCTGCCCTGGAGCACACTGGGGAAGCAGGCTGCGGG CCTTCCAAAAGTAAAAAATGGTGATATGCAATCGAAGCTTATCCTTAGCCTATGCACATTTGTCTCAGCTGGGCATTGTCTTTTCAGAGA GCTTGTAGCACAAGGGCTACACATGGGCGCCAAGATGGTGGTAGATACACCTTGGTGCACTTTTTGTTTTACTTGTTTCTTAAGACTATT TCACAAGTCCTGTGAGGCAAAAAAACAAAACAAAACAAAACAACCAAACAAATACAATCTAACTTTTACCCAATCTACAGCAGGAAATCA AAGGAGTGGGTGGAATGAGAGAAAATATGCAAAGAGATCATTTTTAAGTTTGATTTCCTGTCTGTAATTTTCAAGGACTAATATAGCAAA TTTTTCTTCTGCCATTATCATTTATGTCTCCCTATTTACCACACAATAATGTAAATGCAGAGAATGAGGAGGCATCTTTTAAAAGCCTTA GGATATTCTATATGATGACCTCAATATTGACTTTCAGCCATACTGGGAAAACTTACTTTTCATGGAGTGCCACCTAACAGTGAATGTATT AGAGTATAAAATGTTTGCCATGTATACACCTGTATGTGCACATACACACATTACACACACACACAGAATGCACATTTCACACACATATAC TTATTATTCAAGTTGAAACTGCACTCTAATCAATCTGAGTCTATTGCTGTTTCAACTCTTAAAATCAATATCTCCTACATTAGTAGATAT AAACATAATTCAAATATTTAAATATTTAAGAGGAGAAAAGTAACTAGAAAACCAATGAAAAGTGAGGCCATCAGAAATAGAAAATGCCTG GCACGAACAGTCTATCTAAATTCTCAATTTCACTTCAAATTAGAGAATCCATAATGGACTAGAATATAAATTACAAACACATACACACAT CTTCACTTAAAGTTGTTTTAAGTTCTTTGAAGTTCTGACATGTTTTTAGCCAGGGTTATTTGTTCAGGTTCTTCCTTGTTAGGATTCCAG ACTGGAAAGTTGGAAGTCTCAGGAAATGCATGTTTCCATGAGTTTTTTAGTTTCACAGTTTTACAGATCCAACGACACAATCTTTTAATC TTTGGTCACTCAACCAAACAGGAGTTCCGTAGGCAGAGTGCTCACTTTGAATTGCTAATAGAAAATAATGCACAGTGTCCTCAGGATATG CTAAACAAGGTTTTTAAGAGCATTTTATTTTACAGCACTTTAGTCTTTTCAGCTAGATTTCAGTGACACTATGGTGTAAATGCTATATCT GCCATAACTTATTGGTGGCTCCTGTGTTACATACAGTTTTAAATAATGCTCTAAATTGTTTGTTTTCCCAATGATAATGATAAAGTGTTC TGTAGAATTTGTAAAACATGTCAATTGAATCTGTTGAAAATTGTGTAATTGTTATTTCAATTGTGATACTATTTTGTAGGTAATAGTTTT AAACGTATATTTGTATGAGTCAAAAGTATGTGCTTGTATGTGGTATGTGTGTGTAAGTATATAATATCTTATCAAAAATCAAACTTATCC TAAAGAAAAAGGGCACATTGTGACCAGCCTTAATTTATTAACACTTTTTTGTTGTTTTTGCAATTTGGATTTAAAATTGAAACAGAAATT AAGTTTTTGTTAAAAATGGTGTCTTTTAATTTTGTGAGGAATGGGCTTTAGAACCTATCTGAGTTCCCACAAGCAAACTGTCCACCTTGT GAGGTACCCCATTGCTTTTCGTAATAATCAAACATCAATTCATATATTAACTTCATTTTCATACAGACTAATTTGTTTTCATCAACAATA GAACCAGTACACCTTTAAAGTTGACCTTCCCAACATGGCACCCATTTTTCTTTAATGATAAATTTTCCATGAAAAATTGTTTCTCCAAAC CATTACTTTTTAAAATTCAATCTTCCCAAGTAAGATGAACTGCCTTGGTGTTAGGAGAGCTTTTAAAGGCCCATCCATACTAGGTGGTTC CAACATGGTTCTCTTCTCGAGAAAACAAGCATGCAACCCACACACTTTTCTGGTCTGCCCCACGTGTAGAATTAGTCTAGCAATAGAAAA CTCATGACTGACAAGGATCTACACATGTGGTCATGCTTGAAGCAAAAATTCTGTGACCTTCTTTGGGCTTGGATCTGATTACAGAATATT AATTAACTTTCTTATTTCCTTTCTTTCTCCATCCTTAGTTATTCCTTTTCAATATTTAGAGTTGCCAGGTAAAATACAGGATATCCAGTG AAATTTAAATTTCAGATAAACAGTATTTCTTTAGCATATTTCTCATATATTTAATCAGACATACTTTCACTTTAAAAAAAGTTTATCTGA AATTCAAATGTAACTGGGTATGTCCTATATATTTTTTCCTAAATCTCACAATTCTATCCACACTGCCTTTCTATCTTTTTCAGCTGGGCT ATCTATAAGGGGCGAGATCTACCTCCCTCCATACCCTTGTGTTCAGACACCTTATGAATATCTGCAGTCATAATGTCCTTCAAGAAAGAA AACATTGGTCAGCTCTAGGTCCTGCAAATGCTTTTTGAAGGACGAACTCAAATACAGATGGGATAATCAAGTAAATATCTTCATAGGATC AATGCCACCATGTTCAACACTTCCCTTTGCCAGCCTGTTGTGAGGTCCAAGTTTCCCCATTAATCCCTTATATAGCATTTCCCAGTAACT GGGACAACCAAAAACACACCGACATATTAGAAATGCTCCTGAAAAGTGGCAACACCGCCTAACTCAGTACCAGGACCTCTTTTAAATTCA ATTTCTTTTTTCTTTCAGAGAGATAACAAACGAATTCATTATTTCCCCCATTCACATCTTACCACAAATTATTTTTATCAGGTTAAAACT GGTCATCTACGGAATTGTAGAAAGGTGACATAGGAACTGTCTTCACTGCTGGAAGAATAAAAGAGTCTGAGGTATAGACACTGCCCTGGT GACACCTTCTCAGAACATTGTTGGGGGACAGGGGAGGCAGGCGCAAGTAGGGGATAGAATCTGACCCTGACATGCAGCTATCACCTGGCA GAGAGACTCGTCAAAGCAAATTATAACGACCAGTACTATTTTTTTTTGGAATTGAAAACCCAAGAAGCCCTAAAATAAGAACAGTGAGAT CAAAGGCTGGTTTCTAAAACAATGCAGAAAATAGAACCATGTTGGAATTCCTAAATTCTAGCTTTCAAATACTACTGTTTCCAACAGTGA ATCCTTGACAGAGACTGAATGCAGATGGAATTTTGAAACATTTTCAGTAGCTACCTCCTCTCCTGAAATTCCTATAAGTGGCAGAGGAAA ATCCAAATCCTTTAATATAACATGTCCATCTCATGACTCCTGCTTACACACATTTGTGTTGATTTGCTTCATTTCTGGAGGATGGGAATT TGCAGAGCTGGTGACATTTCCTTCATTAGACACCAGAAATTCACCAGAGAGAGACAGATCTGTGCCTTCTCTTTTTAGGATCTGGTTATT GATACTTTAATAAATGTGGTGTAAAGAAAATCCATGGCTACAGTCTGTATAGAAAATGTGAATTTTTTAAATAAGATTGTGTTCTTAATG >63686_63686_4_PDE3B-PLCXD3_PDE3B_chr11_14889304_ENST00000455098_PLCXD3_chr5_41313872_ENST00000377801_length(amino acids)=1000AA_BP= MRRDERDAKAMRSLQPPDGAGSPPESLRNGYVKSCVSPLRQDPPRGFFFHLCRFCNVELRPPPASPQQPRRCSPFCRARLSLGALAAFVL ALLLGAEPESWAAGAAWLRTLLSVCSHSLSPLFSIACAFFFLTCFLTRTKRGPGPGRSCGSWWLLALPACCYLGDFLVWQWWSWPWGDGD AGSAAPHTPPEAAAGRLLLVLSCVGLLLTLAHPLRLRHCVLVLLLASFVWWVSFTSLGSLPSALRPLLSGLVGGAGCLLALGLDHFFQIR EAPLHPRLSSAAEEKVPVIRPRRRSSCVSLGETAASYYGSCKIFRRPSLPCISREQMILWDWDLKQWYKPHYQNSGGGNGVDLSVLNEAR NMVSDLLTDPSLPPQGLNRNSLPTPQLRRSSGTSGLLPVEQSSRWDRNNGKRPHQEFGISSQGCYLNGPFNSNLLTIPKQRSSSVSLTHH VGLRRAGVLSSLSPVNSSNHGPVSTGSLTNRSPIEFPDTADFLNKPSVILQRSLGNAPNTPDFYQQLRNSDSNLCNSCGHQMLKYVSTSE SDGTDCCSGKSGEEENIFSKESFKLMETQQEEETEKKDSRKLFQEGDKWLTEEAQSEQQTNIEQEVSLDLILVEEYDSLIEKMSNWNFPI FELVEKMGEKSGRILSQVMYTLFQDTGLLEIFKIPTQQFMNYFRALENGYRDIPYHNRIHATDVLHAVWYLTTRPVPGLQQIHNGCGTGN ETDSDGRINHGRIAYISSKSCSNPDESYGCLSSNIPALELMALYVAAAMHDYDHPGRTNAFLVATNAPQAVLYNDRSVLENHHAASAWNL YLSRPEYNFLLHLDHVEFKRFRFLVIEAILATDLKKHFDFLAEFNAKANDVNSNGIEWSNENDRLLVCQVCIKLADINGPAKVRDLHLKW TEGIVNEFYEQGDEEANLGLPISPFMDRSSPQLAKLQESFITHIVGPLCNSYDAAGLLPGQWLEAEEDNDTESGDDEDGEELDTEDEEME -------------------------------------------------------------- |
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Fusion Gene PPI Analysis for PDE3B-PLCXD3 |
| Go to ChiPPI (Chimeric Protein-Protein interactions) to see the chimeric PPI interaction in |
| Protein-protein interactors with each fusion partner protein in wild-type (BIOGRID-3.4.160) |
| Hgene | Hgene's interactors | Tgene | Tgene's interactors |
| - Retained PPIs in in-frame fusion. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Still interaction with |
| Hgene | PDE3B | chr11:14889304 | chr5:41313872 | ENST00000282096 | + | 15 | 16 | 436_460 | 1046.3333333333333 | 1113.0 | PIK3R6 |
| Hgene | PDE3B | chr11:14889304 | chr5:41313872 | ENST00000282096 | + | 15 | 16 | 1_25 | 1046.3333333333333 | 1113.0 | RAPGEF3 |
| - Lost PPIs in in-frame fusion. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Interaction lost with |
| - Retained PPIs, but lost function due to frame-shift fusion. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Interaction lost with |
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Related Drugs for PDE3B-PLCXD3 |
| Drugs targeting genes involved in this fusion gene. (DrugBank Version 5.1.8 2021-05-08) |
| Partner | Gene | UniProtAcc | DrugBank ID | Drug name | Drug activity | Drug type | Drug status |
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Related Diseases for PDE3B-PLCXD3 |
| Diseases associated with fusion partners. (DisGeNet 4.0) |
| Partner | Gene | Disease ID | Disease name | # pubmeds | Source |
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