FusionGDB Logo

Home

Download

Statistics

Examples

Help

Contact
Center for Computational Systems Medicine
leaf

Fusion Gene Summary

leaf

Fusion Gene ORF analysis

leaf

Fusion Genomic Features

leaf

Fusion Protein Features

leaf

Fusion Gene Sequence

leaf

Fusion Gene PPI analysis

leaf

Related Drugs

leaf

Related Diseases

Fusion gene:PDE4D-ELOVL7 (FusionGDB2 ID:63723)

Fusion Gene Summary for PDE4D-ELOVL7

check button Fusion gene summary
Fusion gene informationFusion gene name: PDE4D-ELOVL7
Fusion gene ID: 63723
HgeneTgene
Gene symbol

PDE4D

ELOVL7

Gene ID

5144

79993

Gene namephosphodiesterase 4DELOVL fatty acid elongase 7
SynonymsACRDYS2|DPDE3|HSPDE4D|PDE43|PDE4DN2|STRK1-
Cytomap

5q11.2-q12.1

5q12.1

Type of geneprotein-codingprotein-coding
DescriptioncAMP-specific 3',5'-cyclic phosphodiesterase 4DcAMP-specific phosphodiesterase PDE4D6phosphodiesterase 4D, cAMP-specific (phosphodiesterase E3 dunce homolog, Drosophila)testicular tissue protein Li 136elongation of very long chain fatty acids protein 73-keto acyl-CoA synthase ELOVL7ELOVL FA elongase 7ELOVL family member 7, elongation of long chain fatty acidsvery long chain 3-ketoacyl-CoA synthase 7very long chain 3-oxoacyl-CoA synthase 7
Modification date2020031320200313
UniProtAcc.

A1L3X0

Ensembl transtripts involved in fusion geneENST00000502484, ENST00000546160, 
ENST00000317118, ENST00000340635, 
ENST00000358923, ENST00000360047, 
ENST00000405755, ENST00000502575, 
ENST00000503258, ENST00000503947, 
ENST00000507116, 		ENST00000425382, 
ENST00000438340, ENST00000505959, 
ENST00000508821, 
Fusion gene scores* DoF score40 X 32 X 12=153606 X 6 X 8=288
# samples 5612
** MAII scorelog2(56/15360*10)=-4.77760757866355
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0		log2(12/288*10)=-1.26303440583379
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0
Context

PubMed: PDE4D [Title/Abstract] AND ELOVL7 [Title/Abstract] AND fusion [Title/Abstract]

Most frequent breakpointPDE4D(59481384)-ELOVL7(60050660), # samples:2
PDE4D(59783769)-ELOVL7(60095057), # samples:2
Anticipated loss of major functional domain due to fusion event.PDE4D-ELOVL7 seems lost the major protein functional domain in Hgene partner, which is a cell metabolism gene due to the frame-shifted ORF.
PDE4D-ELOVL7 seems lost the major protein functional domain in Hgene partner, which is a IUPHAR drug target due to the frame-shifted ORF.
PDE4D-ELOVL7 seems lost the major protein functional domain in Tgene partner, which is a cell metabolism gene due to the frame-shifted ORF.
* DoF score (Degree of Frequency) = # partners X # break points X # cancer types
** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10)

check button Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez
PartnerGeneGO IDGO termPubMed ID
TgeneELOVL7

GO:0019367

fatty acid elongation, saturated fatty acid

19826053

TgeneELOVL7

GO:0034626

fatty acid elongation, polyunsaturated fatty acid

20937905

TgeneELOVL7

GO:0042761

very long-chain fatty acid biosynthetic process

19826053|20937905


check buttonFusion gene breakpoints across PDE4D (5'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.
all structure

check buttonFusion gene breakpoints across ELOVL7 (3'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.
all structure

check button Fusion gene information from two resources (ChiTars 5.0 and ChimerDB 4.0)
* All genome coordinats were lifted-over on hg19.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
SourceDiseaseSampleHgeneHchrHbpHstrandTgeneTchrTbpTstrand
ChimerDB4LUADTCGA-44-7660-01APDE4Dchr5

59481384

-ELOVL7chr5

60050660

-
ChimerDB4PRADTCGA-EJ-7785-01APDE4Dchr5

59284315

-ELOVL7chr5

60095057

-
ChimerDB4PRADTCGA-G9-6342-01APDE4Dchr5

59481384

-ELOVL7chr5

60083258

-
ChimerDB4PRADTCGA-KC-A7FA-01APDE4Dchr5

59783769

-ELOVL7chr5

60083258

-
ChimerDB4PRADTCGA-V1-A9Z9-01APDE4Dchr5

59783769

-ELOVL7chr5

60095057

-
ChimerDB4PRADTCGA-V1-A9Z9PDE4Dchr5

59783769

-ELOVL7chr5

60095057

-


Top

Fusion Gene ORF analysis for PDE4D-ELOVL7

check button Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
ORFHenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrand
5CDS-5UTRENST00000502484ENST00000425382PDE4Dchr5

59481384

-ELOVL7chr5

60083258

-
5CDS-5UTRENST00000502484ENST00000438340PDE4Dchr5

59481384

-ELOVL7chr5

60083258

-
5CDS-5UTRENST00000502484ENST00000505959PDE4Dchr5

59284315

-ELOVL7chr5

60095057

-
5CDS-5UTRENST00000502484ENST00000505959PDE4Dchr5

59481384

-ELOVL7chr5

60083258

-
5CDS-5UTRENST00000502484ENST00000508821PDE4Dchr5

59284315

-ELOVL7chr5

60095057

-
5CDS-5UTRENST00000502484ENST00000508821PDE4Dchr5

59481384

-ELOVL7chr5

60083258

-
5CDS-5UTRENST00000546160ENST00000425382PDE4Dchr5

59481384

-ELOVL7chr5

60083258

-
5CDS-5UTRENST00000546160ENST00000438340PDE4Dchr5

59481384

-ELOVL7chr5

60083258

-
5CDS-5UTRENST00000546160ENST00000505959PDE4Dchr5

59284315

-ELOVL7chr5

60095057

-
5CDS-5UTRENST00000546160ENST00000505959PDE4Dchr5

59481384

-ELOVL7chr5

60083258

-
5CDS-5UTRENST00000546160ENST00000508821PDE4Dchr5

59284315

-ELOVL7chr5

60095057

-
5CDS-5UTRENST00000546160ENST00000508821PDE4Dchr5

59481384

-ELOVL7chr5

60083258

-
5CDS-intronENST00000502484ENST00000425382PDE4Dchr5

59284315

-ELOVL7chr5

60095057

-
5CDS-intronENST00000502484ENST00000438340PDE4Dchr5

59284315

-ELOVL7chr5

60095057

-
5CDS-intronENST00000546160ENST00000425382PDE4Dchr5

59284315

-ELOVL7chr5

60095057

-
5CDS-intronENST00000546160ENST00000438340PDE4Dchr5

59284315

-ELOVL7chr5

60095057

-
5UTR-5UTRENST00000502484ENST00000425382PDE4Dchr5

59783769

-ELOVL7chr5

60083258

-
5UTR-5UTRENST00000502484ENST00000438340PDE4Dchr5

59783769

-ELOVL7chr5

60083258

-
5UTR-5UTRENST00000502484ENST00000505959PDE4Dchr5

59783769

-ELOVL7chr5

60083258

-
5UTR-5UTRENST00000502484ENST00000505959PDE4Dchr5

59783769

-ELOVL7chr5

60095057

-
5UTR-5UTRENST00000502484ENST00000508821PDE4Dchr5

59783769

-ELOVL7chr5

60083258

-
5UTR-5UTRENST00000502484ENST00000508821PDE4Dchr5

59783769

-ELOVL7chr5

60095057

-
5UTR-intronENST00000502484ENST00000425382PDE4Dchr5

59783769

-ELOVL7chr5

60095057

-
5UTR-intronENST00000502484ENST00000438340PDE4Dchr5

59783769

-ELOVL7chr5

60095057

-
Frame-shiftENST00000502484ENST00000425382PDE4Dchr5

59481384

-ELOVL7chr5

60050660

-
Frame-shiftENST00000502484ENST00000438340PDE4Dchr5

59481384

-ELOVL7chr5

60050660

-
Frame-shiftENST00000502484ENST00000505959PDE4Dchr5

59481384

-ELOVL7chr5

60050660

-
Frame-shiftENST00000502484ENST00000508821PDE4Dchr5

59481384

-ELOVL7chr5

60050660

-
Frame-shiftENST00000546160ENST00000425382PDE4Dchr5

59481384

-ELOVL7chr5

60050660

-
Frame-shiftENST00000546160ENST00000438340PDE4Dchr5

59481384

-ELOVL7chr5

60050660

-
In-frameENST00000546160ENST00000505959PDE4Dchr5

59481384

-ELOVL7chr5

60050660

-
In-frameENST00000546160ENST00000508821PDE4Dchr5

59481384

-ELOVL7chr5

60050660

-
intron-3CDSENST00000317118ENST00000425382PDE4Dchr5

59481384

-ELOVL7chr5

60050660

-
intron-3CDSENST00000317118ENST00000438340PDE4Dchr5

59481384

-ELOVL7chr5

60050660

-
intron-3CDSENST00000317118ENST00000505959PDE4Dchr5

59481384

-ELOVL7chr5

60050660

-
intron-3CDSENST00000317118ENST00000508821PDE4Dchr5

59481384

-ELOVL7chr5

60050660

-
intron-3CDSENST00000340635ENST00000425382PDE4Dchr5

59481384

-ELOVL7chr5

60050660

-
intron-3CDSENST00000340635ENST00000438340PDE4Dchr5

59481384

-ELOVL7chr5

60050660

-
intron-3CDSENST00000340635ENST00000505959PDE4Dchr5

59481384

-ELOVL7chr5

60050660

-
intron-3CDSENST00000340635ENST00000508821PDE4Dchr5

59481384

-ELOVL7chr5

60050660

-
intron-3CDSENST00000358923ENST00000425382PDE4Dchr5

59481384

-ELOVL7chr5

60050660

-
intron-3CDSENST00000358923ENST00000438340PDE4Dchr5

59481384

-ELOVL7chr5

60050660

-
intron-3CDSENST00000358923ENST00000505959PDE4Dchr5

59481384

-ELOVL7chr5

60050660

-
intron-3CDSENST00000358923ENST00000508821PDE4Dchr5

59481384

-ELOVL7chr5

60050660

-
intron-3CDSENST00000360047ENST00000425382PDE4Dchr5

59481384

-ELOVL7chr5

60050660

-
intron-3CDSENST00000360047ENST00000438340PDE4Dchr5

59481384

-ELOVL7chr5

60050660

-
intron-3CDSENST00000360047ENST00000505959PDE4Dchr5

59481384

-ELOVL7chr5

60050660

-
intron-3CDSENST00000360047ENST00000508821PDE4Dchr5

59481384

-ELOVL7chr5

60050660

-
intron-3CDSENST00000405755ENST00000425382PDE4Dchr5

59481384

-ELOVL7chr5

60050660

-
intron-3CDSENST00000405755ENST00000438340PDE4Dchr5

59481384

-ELOVL7chr5

60050660

-
intron-3CDSENST00000405755ENST00000505959PDE4Dchr5

59481384

-ELOVL7chr5

60050660

-
intron-3CDSENST00000405755ENST00000508821PDE4Dchr5

59481384

-ELOVL7chr5

60050660

-
intron-3CDSENST00000502575ENST00000425382PDE4Dchr5

59481384

-ELOVL7chr5

60050660

-
intron-3CDSENST00000502575ENST00000438340PDE4Dchr5

59481384

-ELOVL7chr5

60050660

-
intron-3CDSENST00000502575ENST00000505959PDE4Dchr5

59481384

-ELOVL7chr5

60050660

-
intron-3CDSENST00000502575ENST00000508821PDE4Dchr5

59481384

-ELOVL7chr5

60050660

-
intron-3CDSENST00000503258ENST00000425382PDE4Dchr5

59481384

-ELOVL7chr5

60050660

-
intron-3CDSENST00000503258ENST00000438340PDE4Dchr5

59481384

-ELOVL7chr5

60050660

-
intron-3CDSENST00000503258ENST00000505959PDE4Dchr5

59481384

-ELOVL7chr5

60050660

-
intron-3CDSENST00000503258ENST00000508821PDE4Dchr5

59481384

-ELOVL7chr5

60050660

-
intron-3CDSENST00000503947ENST00000425382PDE4Dchr5

59481384

-ELOVL7chr5

60050660

-
intron-3CDSENST00000503947ENST00000438340PDE4Dchr5

59481384

-ELOVL7chr5

60050660

-
intron-3CDSENST00000503947ENST00000505959PDE4Dchr5

59481384

-ELOVL7chr5

60050660

-
intron-3CDSENST00000503947ENST00000508821PDE4Dchr5

59481384

-ELOVL7chr5

60050660

-
intron-3CDSENST00000507116ENST00000425382PDE4Dchr5

59481384

-ELOVL7chr5

60050660

-
intron-3CDSENST00000507116ENST00000438340PDE4Dchr5

59481384

-ELOVL7chr5

60050660

-
intron-3CDSENST00000507116ENST00000505959PDE4Dchr5

59481384

-ELOVL7chr5

60050660

-
intron-3CDSENST00000507116ENST00000508821PDE4Dchr5

59481384

-ELOVL7chr5

60050660

-
intron-5UTRENST00000317118ENST00000425382PDE4Dchr5

59481384

-ELOVL7chr5

60083258

-
intron-5UTRENST00000317118ENST00000425382PDE4Dchr5

59783769

-ELOVL7chr5

60083258

-
intron-5UTRENST00000317118ENST00000438340PDE4Dchr5

59481384

-ELOVL7chr5

60083258

-
intron-5UTRENST00000317118ENST00000438340PDE4Dchr5

59783769

-ELOVL7chr5

60083258

-
intron-5UTRENST00000317118ENST00000505959PDE4Dchr5

59284315

-ELOVL7chr5

60095057

-
intron-5UTRENST00000317118ENST00000505959PDE4Dchr5

59481384

-ELOVL7chr5

60083258

-
intron-5UTRENST00000317118ENST00000505959PDE4Dchr5

59783769

-ELOVL7chr5

60083258

-
intron-5UTRENST00000317118ENST00000505959PDE4Dchr5

59783769

-ELOVL7chr5

60095057

-
intron-5UTRENST00000317118ENST00000508821PDE4Dchr5

59284315

-ELOVL7chr5

60095057

-
intron-5UTRENST00000317118ENST00000508821PDE4Dchr5

59481384

-ELOVL7chr5

60083258

-
intron-5UTRENST00000317118ENST00000508821PDE4Dchr5

59783769

-ELOVL7chr5

60083258

-
intron-5UTRENST00000317118ENST00000508821PDE4Dchr5

59783769

-ELOVL7chr5

60095057

-
intron-5UTRENST00000340635ENST00000425382PDE4Dchr5

59481384

-ELOVL7chr5

60083258

-
intron-5UTRENST00000340635ENST00000425382PDE4Dchr5

59783769

-ELOVL7chr5

60083258

-
intron-5UTRENST00000340635ENST00000438340PDE4Dchr5

59481384

-ELOVL7chr5

60083258

-
intron-5UTRENST00000340635ENST00000438340PDE4Dchr5

59783769

-ELOVL7chr5

60083258

-
intron-5UTRENST00000340635ENST00000505959PDE4Dchr5

59284315

-ELOVL7chr5

60095057

-
intron-5UTRENST00000340635ENST00000505959PDE4Dchr5

59481384

-ELOVL7chr5

60083258

-
intron-5UTRENST00000340635ENST00000505959PDE4Dchr5

59783769

-ELOVL7chr5

60083258

-
intron-5UTRENST00000340635ENST00000505959PDE4Dchr5

59783769

-ELOVL7chr5

60095057

-
intron-5UTRENST00000340635ENST00000508821PDE4Dchr5

59284315

-ELOVL7chr5

60095057

-
intron-5UTRENST00000340635ENST00000508821PDE4Dchr5

59481384

-ELOVL7chr5

60083258

-
intron-5UTRENST00000340635ENST00000508821PDE4Dchr5

59783769

-ELOVL7chr5

60083258

-
intron-5UTRENST00000340635ENST00000508821PDE4Dchr5

59783769

-ELOVL7chr5

60095057

-
intron-5UTRENST00000358923ENST00000425382PDE4Dchr5

59481384

-ELOVL7chr5

60083258

-
intron-5UTRENST00000358923ENST00000425382PDE4Dchr5

59783769

-ELOVL7chr5

60083258

-
intron-5UTRENST00000358923ENST00000438340PDE4Dchr5

59481384

-ELOVL7chr5

60083258

-
intron-5UTRENST00000358923ENST00000438340PDE4Dchr5

59783769

-ELOVL7chr5

60083258

-
intron-5UTRENST00000358923ENST00000505959PDE4Dchr5

59284315

-ELOVL7chr5

60095057

-
intron-5UTRENST00000358923ENST00000505959PDE4Dchr5

59481384

-ELOVL7chr5

60083258

-
intron-5UTRENST00000358923ENST00000505959PDE4Dchr5

59783769

-ELOVL7chr5

60083258

-
intron-5UTRENST00000358923ENST00000505959PDE4Dchr5

59783769

-ELOVL7chr5

60095057

-
intron-5UTRENST00000358923ENST00000508821PDE4Dchr5

59284315

-ELOVL7chr5

60095057

-
intron-5UTRENST00000358923ENST00000508821PDE4Dchr5

59481384

-ELOVL7chr5

60083258

-
intron-5UTRENST00000358923ENST00000508821PDE4Dchr5

59783769

-ELOVL7chr5

60083258

-
intron-5UTRENST00000358923ENST00000508821PDE4Dchr5

59783769

-ELOVL7chr5

60095057

-
intron-5UTRENST00000360047ENST00000425382PDE4Dchr5

59481384

-ELOVL7chr5

60083258

-
intron-5UTRENST00000360047ENST00000425382PDE4Dchr5

59783769

-ELOVL7chr5

60083258

-
intron-5UTRENST00000360047ENST00000438340PDE4Dchr5

59481384

-ELOVL7chr5

60083258

-
intron-5UTRENST00000360047ENST00000438340PDE4Dchr5

59783769

-ELOVL7chr5

60083258

-
intron-5UTRENST00000360047ENST00000505959PDE4Dchr5

59284315

-ELOVL7chr5

60095057

-
intron-5UTRENST00000360047ENST00000505959PDE4Dchr5

59481384

-ELOVL7chr5

60083258

-
intron-5UTRENST00000360047ENST00000505959PDE4Dchr5

59783769

-ELOVL7chr5

60083258

-
intron-5UTRENST00000360047ENST00000505959PDE4Dchr5

59783769

-ELOVL7chr5

60095057

-
intron-5UTRENST00000360047ENST00000508821PDE4Dchr5

59284315

-ELOVL7chr5

60095057

-
intron-5UTRENST00000360047ENST00000508821PDE4Dchr5

59481384

-ELOVL7chr5

60083258

-
intron-5UTRENST00000360047ENST00000508821PDE4Dchr5

59783769

-ELOVL7chr5

60083258

-
intron-5UTRENST00000360047ENST00000508821PDE4Dchr5

59783769

-ELOVL7chr5

60095057

-
intron-5UTRENST00000405755ENST00000425382PDE4Dchr5

59481384

-ELOVL7chr5

60083258

-
intron-5UTRENST00000405755ENST00000425382PDE4Dchr5

59783769

-ELOVL7chr5

60083258

-
intron-5UTRENST00000405755ENST00000438340PDE4Dchr5

59481384

-ELOVL7chr5

60083258

-
intron-5UTRENST00000405755ENST00000438340PDE4Dchr5

59783769

-ELOVL7chr5

60083258

-
intron-5UTRENST00000405755ENST00000505959PDE4Dchr5

59284315

-ELOVL7chr5

60095057

-
intron-5UTRENST00000405755ENST00000505959PDE4Dchr5

59481384

-ELOVL7chr5

60083258

-
intron-5UTRENST00000405755ENST00000505959PDE4Dchr5

59783769

-ELOVL7chr5

60083258

-
intron-5UTRENST00000405755ENST00000505959PDE4Dchr5

59783769

-ELOVL7chr5

60095057

-
intron-5UTRENST00000405755ENST00000508821PDE4Dchr5

59284315

-ELOVL7chr5

60095057

-
intron-5UTRENST00000405755ENST00000508821PDE4Dchr5

59481384

-ELOVL7chr5

60083258

-
intron-5UTRENST00000405755ENST00000508821PDE4Dchr5

59783769

-ELOVL7chr5

60083258

-
intron-5UTRENST00000405755ENST00000508821PDE4Dchr5

59783769

-ELOVL7chr5

60095057

-
intron-5UTRENST00000502575ENST00000425382PDE4Dchr5

59481384

-ELOVL7chr5

60083258

-
intron-5UTRENST00000502575ENST00000425382PDE4Dchr5

59783769

-ELOVL7chr5

60083258

-
intron-5UTRENST00000502575ENST00000438340PDE4Dchr5

59481384

-ELOVL7chr5

60083258

-
intron-5UTRENST00000502575ENST00000438340PDE4Dchr5

59783769

-ELOVL7chr5

60083258

-
intron-5UTRENST00000502575ENST00000505959PDE4Dchr5

59284315

-ELOVL7chr5

60095057

-
intron-5UTRENST00000502575ENST00000505959PDE4Dchr5

59481384

-ELOVL7chr5

60083258

-
intron-5UTRENST00000502575ENST00000505959PDE4Dchr5

59783769

-ELOVL7chr5

60083258

-
intron-5UTRENST00000502575ENST00000505959PDE4Dchr5

59783769

-ELOVL7chr5

60095057

-
intron-5UTRENST00000502575ENST00000508821PDE4Dchr5

59284315

-ELOVL7chr5

60095057

-
intron-5UTRENST00000502575ENST00000508821PDE4Dchr5

59481384

-ELOVL7chr5

60083258

-
intron-5UTRENST00000502575ENST00000508821PDE4Dchr5

59783769

-ELOVL7chr5

60083258

-
intron-5UTRENST00000502575ENST00000508821PDE4Dchr5

59783769

-ELOVL7chr5

60095057

-
intron-5UTRENST00000503258ENST00000425382PDE4Dchr5

59481384

-ELOVL7chr5

60083258

-
intron-5UTRENST00000503258ENST00000425382PDE4Dchr5

59783769

-ELOVL7chr5

60083258

-
intron-5UTRENST00000503258ENST00000438340PDE4Dchr5

59481384

-ELOVL7chr5

60083258

-
intron-5UTRENST00000503258ENST00000438340PDE4Dchr5

59783769

-ELOVL7chr5

60083258

-
intron-5UTRENST00000503258ENST00000505959PDE4Dchr5

59284315

-ELOVL7chr5

60095057

-
intron-5UTRENST00000503258ENST00000505959PDE4Dchr5

59481384

-ELOVL7chr5

60083258

-
intron-5UTRENST00000503258ENST00000505959PDE4Dchr5

59783769

-ELOVL7chr5

60083258

-
intron-5UTRENST00000503258ENST00000505959PDE4Dchr5

59783769

-ELOVL7chr5

60095057

-
intron-5UTRENST00000503258ENST00000508821PDE4Dchr5

59284315

-ELOVL7chr5

60095057

-
intron-5UTRENST00000503258ENST00000508821PDE4Dchr5

59481384

-ELOVL7chr5

60083258

-
intron-5UTRENST00000503258ENST00000508821PDE4Dchr5

59783769

-ELOVL7chr5

60083258

-
intron-5UTRENST00000503258ENST00000508821PDE4Dchr5

59783769

-ELOVL7chr5

60095057

-
intron-5UTRENST00000503947ENST00000425382PDE4Dchr5

59481384

-ELOVL7chr5

60083258

-
intron-5UTRENST00000503947ENST00000425382PDE4Dchr5

59783769

-ELOVL7chr5

60083258

-
intron-5UTRENST00000503947ENST00000438340PDE4Dchr5

59481384

-ELOVL7chr5

60083258

-
intron-5UTRENST00000503947ENST00000438340PDE4Dchr5

59783769

-ELOVL7chr5

60083258

-
intron-5UTRENST00000503947ENST00000505959PDE4Dchr5

59284315

-ELOVL7chr5

60095057

-
intron-5UTRENST00000503947ENST00000505959PDE4Dchr5

59481384

-ELOVL7chr5

60083258

-
intron-5UTRENST00000503947ENST00000505959PDE4Dchr5

59783769

-ELOVL7chr5

60083258

-
intron-5UTRENST00000503947ENST00000505959PDE4Dchr5

59783769

-ELOVL7chr5

60095057

-
intron-5UTRENST00000503947ENST00000508821PDE4Dchr5

59284315

-ELOVL7chr5

60095057

-
intron-5UTRENST00000503947ENST00000508821PDE4Dchr5

59481384

-ELOVL7chr5

60083258

-
intron-5UTRENST00000503947ENST00000508821PDE4Dchr5

59783769

-ELOVL7chr5

60083258

-
intron-5UTRENST00000503947ENST00000508821PDE4Dchr5

59783769

-ELOVL7chr5

60095057

-
intron-5UTRENST00000507116ENST00000425382PDE4Dchr5

59481384

-ELOVL7chr5

60083258

-
intron-5UTRENST00000507116ENST00000425382PDE4Dchr5

59783769

-ELOVL7chr5

60083258

-
intron-5UTRENST00000507116ENST00000438340PDE4Dchr5

59481384

-ELOVL7chr5

60083258

-
intron-5UTRENST00000507116ENST00000438340PDE4Dchr5

59783769

-ELOVL7chr5

60083258

-
intron-5UTRENST00000507116ENST00000505959PDE4Dchr5

59284315

-ELOVL7chr5

60095057

-
intron-5UTRENST00000507116ENST00000505959PDE4Dchr5

59481384

-ELOVL7chr5

60083258

-
intron-5UTRENST00000507116ENST00000505959PDE4Dchr5

59783769

-ELOVL7chr5

60083258

-
intron-5UTRENST00000507116ENST00000505959PDE4Dchr5

59783769

-ELOVL7chr5

60095057

-
intron-5UTRENST00000507116ENST00000508821PDE4Dchr5

59284315

-ELOVL7chr5

60095057

-
intron-5UTRENST00000507116ENST00000508821PDE4Dchr5

59481384

-ELOVL7chr5

60083258

-
intron-5UTRENST00000507116ENST00000508821PDE4Dchr5

59783769

-ELOVL7chr5

60083258

-
intron-5UTRENST00000507116ENST00000508821PDE4Dchr5

59783769

-ELOVL7chr5

60095057

-
intron-5UTRENST00000546160ENST00000425382PDE4Dchr5

59783769

-ELOVL7chr5

60083258

-
intron-5UTRENST00000546160ENST00000438340PDE4Dchr5

59783769

-ELOVL7chr5

60083258

-
intron-5UTRENST00000546160ENST00000505959PDE4Dchr5

59783769

-ELOVL7chr5

60083258

-
intron-5UTRENST00000546160ENST00000505959PDE4Dchr5

59783769

-ELOVL7chr5

60095057

-
intron-5UTRENST00000546160ENST00000508821PDE4Dchr5

59783769

-ELOVL7chr5

60083258

-
intron-5UTRENST00000546160ENST00000508821PDE4Dchr5

59783769

-ELOVL7chr5

60095057

-
intron-intronENST00000317118ENST00000425382PDE4Dchr5

59284315

-ELOVL7chr5

60095057

-
intron-intronENST00000317118ENST00000425382PDE4Dchr5

59783769

-ELOVL7chr5

60095057

-
intron-intronENST00000317118ENST00000438340PDE4Dchr5

59284315

-ELOVL7chr5

60095057

-
intron-intronENST00000317118ENST00000438340PDE4Dchr5

59783769

-ELOVL7chr5

60095057

-
intron-intronENST00000340635ENST00000425382PDE4Dchr5

59284315

-ELOVL7chr5

60095057

-
intron-intronENST00000340635ENST00000425382PDE4Dchr5

59783769

-ELOVL7chr5

60095057

-
intron-intronENST00000340635ENST00000438340PDE4Dchr5

59284315

-ELOVL7chr5

60095057

-
intron-intronENST00000340635ENST00000438340PDE4Dchr5

59783769

-ELOVL7chr5

60095057

-
intron-intronENST00000358923ENST00000425382PDE4Dchr5

59284315

-ELOVL7chr5

60095057

-
intron-intronENST00000358923ENST00000425382PDE4Dchr5

59783769

-ELOVL7chr5

60095057

-
intron-intronENST00000358923ENST00000438340PDE4Dchr5

59284315

-ELOVL7chr5

60095057

-
intron-intronENST00000358923ENST00000438340PDE4Dchr5

59783769

-ELOVL7chr5

60095057

-
intron-intronENST00000360047ENST00000425382PDE4Dchr5

59284315

-ELOVL7chr5

60095057

-
intron-intronENST00000360047ENST00000425382PDE4Dchr5

59783769

-ELOVL7chr5

60095057

-
intron-intronENST00000360047ENST00000438340PDE4Dchr5

59284315

-ELOVL7chr5

60095057

-
intron-intronENST00000360047ENST00000438340PDE4Dchr5

59783769

-ELOVL7chr5

60095057

-
intron-intronENST00000405755ENST00000425382PDE4Dchr5

59284315

-ELOVL7chr5

60095057

-
intron-intronENST00000405755ENST00000425382PDE4Dchr5

59783769

-ELOVL7chr5

60095057

-
intron-intronENST00000405755ENST00000438340PDE4Dchr5

59284315

-ELOVL7chr5

60095057

-
intron-intronENST00000405755ENST00000438340PDE4Dchr5

59783769

-ELOVL7chr5

60095057

-
intron-intronENST00000502575ENST00000425382PDE4Dchr5

59284315

-ELOVL7chr5

60095057

-
intron-intronENST00000502575ENST00000425382PDE4Dchr5

59783769

-ELOVL7chr5

60095057

-
intron-intronENST00000502575ENST00000438340PDE4Dchr5

59284315

-ELOVL7chr5

60095057

-
intron-intronENST00000502575ENST00000438340PDE4Dchr5

59783769

-ELOVL7chr5

60095057

-
intron-intronENST00000503258ENST00000425382PDE4Dchr5

59284315

-ELOVL7chr5

60095057

-
intron-intronENST00000503258ENST00000425382PDE4Dchr5

59783769

-ELOVL7chr5

60095057

-
intron-intronENST00000503258ENST00000438340PDE4Dchr5

59284315

-ELOVL7chr5

60095057

-
intron-intronENST00000503258ENST00000438340PDE4Dchr5

59783769

-ELOVL7chr5

60095057

-
intron-intronENST00000503947ENST00000425382PDE4Dchr5

59284315

-ELOVL7chr5

60095057

-
intron-intronENST00000503947ENST00000425382PDE4Dchr5

59783769

-ELOVL7chr5

60095057

-
intron-intronENST00000503947ENST00000438340PDE4Dchr5

59284315

-ELOVL7chr5

60095057

-
intron-intronENST00000503947ENST00000438340PDE4Dchr5

59783769

-ELOVL7chr5

60095057

-
intron-intronENST00000507116ENST00000425382PDE4Dchr5

59284315

-ELOVL7chr5

60095057

-
intron-intronENST00000507116ENST00000425382PDE4Dchr5

59783769

-ELOVL7chr5

60095057

-
intron-intronENST00000507116ENST00000438340PDE4Dchr5

59284315

-ELOVL7chr5

60095057

-
intron-intronENST00000507116ENST00000438340PDE4Dchr5

59783769

-ELOVL7chr5

60095057

-
intron-intronENST00000546160ENST00000425382PDE4Dchr5

59783769

-ELOVL7chr5

60095057

-
intron-intronENST00000546160ENST00000438340PDE4Dchr5

59783769

-ELOVL7chr5

60095057

-

check buttonORFfinder result based on the fusion transcript sequence of in-frame fusion genes.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandSeq length
(transcript)		BP loci
(transcript)		Predicted start
(transcript)		Predicted stop
(transcript)		Seq length
(amino acids)
ENST00000546160PDE4Dchr559481384-ENST00000508821ELOVL7chr560050660-3085423290110
ENST00000546160PDE4Dchr559481384-ENST00000505959ELOVL7chr560050660-3083422651238289

check buttonDeepORF prediction of the coding potential based on the fusion transcript sequence of in-frame fusion genes. DeepORF is a coding potential classifier based on convolutional neural network by comparing the real Ribo-seq data. If the no-coding score < 0.5 and coding score > 0.5, then the in-frame fusion transcript is predicted as being likely translated.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandNo-coding scoreCoding score
ENST00000546160ENST00000508821PDE4Dchr559481384-ELOVL7chr560050660-0.54938620.4506138
ENST00000546160ENST00000505959PDE4Dchr559481384-ELOVL7chr560050660-0.75699390.24300613

Top

Fusion Genomic Features for PDE4D-ELOVL7


check buttonFusionAI prediction of the potential fusion gene breakpoint based on the pre-mature RNA sequence context (+/- 5kb of individual partner genes, total 20kb length sequence). FusionAI is a fusion gene breakpoint classifier based on convolutional neural network by comparing the fusion positive and negative sequence context of ~ 20K fusion gene data. From here, we can have the relative potentency of the 20K genomic sequence how individual sequnce will be likely used as the gene fusion breakpoints.
HgeneHchrHbpHstrandTgeneTchrTbpTstrand1-pp (fusion gene breakpoint)

check buttonDistribution of 44 human genomic features loci across 20kb length fusion breakpoint regions. We integrated a total of 44 different types of human genomic feature loci information across five big categories including virus integration sites, repeats, structural variants, chromatin states, and gene expression regulation. More details are in help page.
genomic feature

check buttonDistribution of 44 human genomic features loci across 20kb length fusion breakpoint regions that are ovelapped with the top 1% feature importance score regions. More details are in help page.

Top

Fusion Protein Features for PDE4D-ELOVL7


check button Four levels of functional features of fusion genes
Go to FGviewer search page for the most frequent breakpoint (https://ccsmweb.uth.edu/FGviewer/chr5:59481384/chr5:60050660)
- FGviewer provides the online visualization of the retention search of the protein functional features across DNA, RNA, protein, and pathological levels.
- How to search
1. Put your fusion gene symbol.
2. Press the tab key until there will be shown the breakpoint information filled.
4. Go down and press 'Search' tab twice.
4. Go down to have the hyperlink of the search result.
5. Click the hyperlink.
6. See the FGviewer result for your fusion gene.
FGviewer

check buttonMain function of each fusion partner protein. (from UniProt)
HgeneTgene
.ELOVL7

A1L3X0

FUNCTION: Transcriptional activator which is required for calcium-dependent dendritic growth and branching in cortical neurons. Recruits CREB-binding protein (CREBBP) to nuclear bodies. Component of the CREST-BRG1 complex, a multiprotein complex that regulates promoter activation by orchestrating a calcium-dependent release of a repressor complex and a recruitment of an activator complex. In resting neurons, transcription of the c-FOS promoter is inhibited by BRG1-dependent recruitment of a phospho-RB1-HDAC1 repressor complex. Upon calcium influx, RB1 is dephosphorylated by calcineurin, which leads to release of the repressor complex. At the same time, there is increased recruitment of CREBBP to the promoter by a CREST-dependent mechanism, which leads to transcriptional activation. The CREST-BRG1 complex also binds to the NR2B promoter, and activity-dependent induction of NR2B expression involves a release of HDAC1 and recruitment of CREBBP (By similarity). {ECO:0000250}.FUNCTION: Catalyzes the first and rate-limiting reaction of the four reactions that constitute the long-chain fatty acids elongation cycle. This endoplasmic reticulum-bound enzymatic process allows the addition of 2 carbons to the chain of long- and very long-chain fatty acids (VLCFAs) per cycle. Condensing enzyme with higher activity toward C18 acyl-CoAs, especially C18:3(n-3) acyl-CoAs and C18:3(n-6)-CoAs. Also active toward C20:4-, C18:0-, C18:1-, C18:2- and C16:0-CoAs, and weakly toward C20:0-CoA. Little or no activity toward C22:0-, C24:0-, or C26:0-CoAs. May participate in the production of saturated and polyunsaturated VLCFAs of different chain lengths that are involved in multiple biological processes as precursors of membrane lipids and lipid mediators. {ECO:0000255|HAMAP-Rule:MF_03207, ECO:0000269|PubMed:19826053, ECO:0000269|PubMed:20937905, ECO:0000269|PubMed:21959040}.

check buttonRetention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at

download page


* Minus value of BPloci means that the break pointn is located before the CDS.
- In-frame and retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
TgeneELOVL7chr5:59481384chr5:60050660ENST0000042538268277_281212282.0MotifDi-lysine motif
TgeneELOVL7chr5:59481384chr5:60050660ENST0000043834068277_281212282.0MotifDi-lysine motif
TgeneELOVL7chr5:59481384chr5:60050660ENST0000050882179277_281212282.0MotifDi-lysine motif
TgeneELOVL7chr5:59481384chr5:60050660ENST0000042538268237_257212282.0TransmembraneHelical
TgeneELOVL7chr5:59481384chr5:60050660ENST0000043834068237_257212282.0TransmembraneHelical
TgeneELOVL7chr5:59481384chr5:60050660ENST0000050882179237_257212282.0TransmembraneHelical

- In-frame and not-retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
HgenePDE4Dchr5:59481384chr5:60050660ENST00000317118-11042_880519.0Compositional biasNote=Pro-rich
HgenePDE4Dchr5:59481384chr5:60050660ENST00000340635-11542_880810.0Compositional biasNote=Pro-rich
HgenePDE4Dchr5:59481384chr5:60050660ENST00000358923-11142_880508.0Compositional biasNote=Pro-rich
HgenePDE4Dchr5:59481384chr5:60050660ENST00000360047-11542_880674.0Compositional biasNote=Pro-rich
HgenePDE4Dchr5:59481384chr5:60050660ENST00000405755-11542_880688.0Compositional biasNote=Pro-rich
HgenePDE4Dchr5:59481384chr5:60050660ENST00000502484-21742_8814749.0Compositional biasNote=Pro-rich
HgenePDE4Dchr5:59481384chr5:60050660ENST00000502575-1642_880220.0Compositional biasNote=Pro-rich
HgenePDE4Dchr5:59481384chr5:60050660ENST00000503258-11542_880680.0Compositional biasNote=Pro-rich
HgenePDE4Dchr5:59481384chr5:60050660ENST00000507116-11542_880746.0Compositional biasNote=Pro-rich
HgenePDE4Dchr5:59481384chr5:60050660ENST00000546160-11642_8814749.0Compositional biasNote=Pro-rich
HgenePDE4Dchr5:59481384chr5:60050660ENST00000317118-110386_7150519.0DomainPDEase
HgenePDE4Dchr5:59481384chr5:60050660ENST00000340635-115386_7150810.0DomainPDEase
HgenePDE4Dchr5:59481384chr5:60050660ENST00000358923-111386_7150508.0DomainPDEase
HgenePDE4Dchr5:59481384chr5:60050660ENST00000360047-115386_7150674.0DomainPDEase
HgenePDE4Dchr5:59481384chr5:60050660ENST00000405755-115386_7150688.0DomainPDEase
HgenePDE4Dchr5:59481384chr5:60050660ENST00000502484-217386_71514749.0DomainPDEase
HgenePDE4Dchr5:59481384chr5:60050660ENST00000502575-16386_7150220.0DomainPDEase
HgenePDE4Dchr5:59481384chr5:60050660ENST00000503258-115386_7150680.0DomainPDEase
HgenePDE4Dchr5:59481384chr5:60050660ENST00000507116-115386_7150746.0DomainPDEase
HgenePDE4Dchr5:59481384chr5:60050660ENST00000546160-116386_71514749.0DomainPDEase
HgenePDE4Dchr5:59481384chr5:60050660ENST00000317118-110462_4660519.0Nucleotide bindingcAMP
HgenePDE4Dchr5:59481384chr5:60050660ENST00000340635-115462_4660810.0Nucleotide bindingcAMP
HgenePDE4Dchr5:59481384chr5:60050660ENST00000358923-111462_4660508.0Nucleotide bindingcAMP
HgenePDE4Dchr5:59481384chr5:60050660ENST00000360047-115462_4660674.0Nucleotide bindingcAMP
HgenePDE4Dchr5:59481384chr5:60050660ENST00000405755-115462_4660688.0Nucleotide bindingcAMP
HgenePDE4Dchr5:59481384chr5:60050660ENST00000502484-217462_46614749.0Nucleotide bindingcAMP
HgenePDE4Dchr5:59481384chr5:60050660ENST00000502575-16462_4660220.0Nucleotide bindingcAMP
HgenePDE4Dchr5:59481384chr5:60050660ENST00000503258-115462_4660680.0Nucleotide bindingcAMP
HgenePDE4Dchr5:59481384chr5:60050660ENST00000507116-115462_4660746.0Nucleotide bindingcAMP
HgenePDE4Dchr5:59481384chr5:60050660ENST00000546160-116462_46614749.0Nucleotide bindingcAMP
TgeneELOVL7chr5:59481384chr5:60050660ENST0000042538268116_136212282.0TransmembraneHelical
TgeneELOVL7chr5:59481384chr5:60050660ENST0000042538268143_162212282.0TransmembraneHelical
TgeneELOVL7chr5:59481384chr5:60050660ENST0000042538268172_194212282.0TransmembraneHelical
TgeneELOVL7chr5:59481384chr5:60050660ENST0000042538268207_227212282.0TransmembraneHelical
TgeneELOVL7chr5:59481384chr5:60050660ENST000004253826828_48212282.0TransmembraneHelical
TgeneELOVL7chr5:59481384chr5:60050660ENST000004253826873_93212282.0TransmembraneHelical
TgeneELOVL7chr5:59481384chr5:60050660ENST0000043834068116_136212282.0TransmembraneHelical
TgeneELOVL7chr5:59481384chr5:60050660ENST0000043834068143_162212282.0TransmembraneHelical
TgeneELOVL7chr5:59481384chr5:60050660ENST0000043834068172_194212282.0TransmembraneHelical
TgeneELOVL7chr5:59481384chr5:60050660ENST0000043834068207_227212282.0TransmembraneHelical
TgeneELOVL7chr5:59481384chr5:60050660ENST000004383406828_48212282.0TransmembraneHelical
TgeneELOVL7chr5:59481384chr5:60050660ENST000004383406873_93212282.0TransmembraneHelical
TgeneELOVL7chr5:59481384chr5:60050660ENST0000050882179116_136212282.0TransmembraneHelical
TgeneELOVL7chr5:59481384chr5:60050660ENST0000050882179143_162212282.0TransmembraneHelical
TgeneELOVL7chr5:59481384chr5:60050660ENST0000050882179172_194212282.0TransmembraneHelical
TgeneELOVL7chr5:59481384chr5:60050660ENST0000050882179207_227212282.0TransmembraneHelical
TgeneELOVL7chr5:59481384chr5:60050660ENST000005088217928_48212282.0TransmembraneHelical
TgeneELOVL7chr5:59481384chr5:60050660ENST000005088217973_93212282.0TransmembraneHelical


Top

Fusion Gene Sequence for PDE4D-ELOVL7


check button For in-frame fusion transcripts, we provide the fusion transcript sequences and fusion amino acid sequences. To have fusion amino acid sequence, we ran ORFfinder and chose the longest ORF among the all predicted ones.
>63723_63723_1_PDE4D-ELOVL7_PDE4D_chr5_59481384_ENST00000546160_ELOVL7_chr5_60050660_ENST00000505959_length(transcript)=3083nt_BP=42nt
ATGAAAAGAAATACCTGTGATTTGCTTTCTCGGAGCAAAAGTGTCCAGTTTGTTATTGTCGCCATCCACATAAGCCAGTTCTTTTTCATG
GAGGATTGCAAGTATCAGTTTCCAGTCTTTGCGTGCATCATTATGAGTTACAGTTTCATGTTTCTGCTGCTCTTTCTCCATTTTTGGTAC
CGTGCTTACACCAAAGGTCAGAGGTTGCCCAAAACTGTGAAAAATGGAACTTGCAAAAACAAAGATAATTGAAGCCCAACATAAGTCTAT
GATCGAAACTGATACATTGTCTTCCTTGACAATCAAGAGATATTTACCTATGCAGTGCATTTTGTATATTTTTCAAAACTAAGAGCTTGT
ATTTTTATGGTAAGTTATTGGGATGTCTGATATTTGAGAGCCCGAAGCTTCCAGATAACAGTCTTCTGATAATTAGAGCCTACAGCAGCC
AGAATTTGTTTTTGTTTTTGTTTTTGTTTTTTTAGCTGCTTTTAAACCTAATCCAAAGGTTTTGTTTAAAACATTTTGTTGCAGTGAAAA
AAAGATATGAAGCAATACAGTACTCTTCAAAGAAGTCCAATAAAGATGAAAAATATCATTAGGTATTTTGAGCACAGACGGAGATCCATG
TGATAAAATAGATTCCTTCTGCTGGGTCTGGAAAGTCTGGAAACCACCTGTAGGCCCTGGCTTTGTCATTTATTGACTGTATTCAGAAGA
TACTATATTTGCTCTAGAGTTAACTCCCATTTTAGCAAGCTAGCACAGGTGAAAATTGAGTGAGTTTTTGATAACTTGTCATTTAAAATC
ATTAATGATAATTTTCAATGGATCTTTTCAGTAGCCATCACCAGTTTTGCTGATAAGACTTCCTCACAACCCATTTGTTGTACAAACTGT
TTCAAAGTAGCAATCCTTTGGGTTAGTACACTTGATACCAAGTTTCATTCAGTTGATTATTTTCAAAACAAGGTGATTTGTTTTAATGGG
TTAATGAATACTTTGCTATTACTGTTTTACAATTAACTTTGTATATCTCTGGAAAGAGGTGAATTTGTCAATGAAAAAAGTATTGTGTAG
TTCAGTGGGAAAAACCTGTTGTCTGTTATAGTATCACATCACTTTCTTACATTGTCATGGTTTAAATTATTATCTTGGTGAAATATATAG
GTTAGATACTTAAATGTTCATATTATTAGCACACTACAGGTACTACCCTTAAATCATAAATAATATTACCCATTGTACACAGTTTCCAGA
TATGAGTTAGAGTGGCTGTGAAGCAACTAGAGGCAAATTGTGGCACAGAGAATATCCAGGGGAAAATTGATTATGTAAGCAAGGGCTGTT
CTACTTTGAGAGAGAGACAGACAGACTACATAATAGTAATATATTATATAATTAATGTTATAGATACACTGAACAATAAAACATTTTCTG
GAATTATGAATTAATTAACAACCTGGATTTCTGTTTCCAGACCTATAAACCATGTAATGAAGGACTGAAATTCGTTTGGCATACACTTTG
TTTCTTTAAAATTGCTAGTTTCTTTCTGTTATTTTTACATTTTCTTGTCAGAGAATCAAAACTATTAGTCAGTAGAGTTTTGTCCATGAA
ATAATATTTGGACATTTGTGAATTTTTCCCTATTTTTTTTCTTCTTTTATTTATACTCAATTTTGAAGCACTGTTTATGTTTGTAGGACT
TTAAACAATTAGTACTTAAAGCCCCAGTTAATTTTGAACACACAGAGATACTTATTGTACTCTGTGTACAGTAAGTATTTTTATGTTTAC
ACTTACCAGATTCATAAGGTTATTTGCCTTTAAGTGATCTTTTGTGATTTTACTTGATTACAGCATGAGAAGGTAAAGGTTGATAAATGG
GAGTAATTACATATATATATATAATTTATTATTTTTTTTTCTGAAGCAGAGTTTTACTCTTGTTGCCCAGGCTAGAGTGCAATGGCACAA
TCTCGGTTCACTGCAACCTCTGCCTCCCAGGTTCAAGTGATTCTCCTGTCTCAGCCTCCCAAGTAGCTGGGATTACAGGTGCCCGCCACC
ATGCTCAGCTAATTTTTGTATTTTTAGTAGAGACAGGGTTGGCCAGGCTGGTCTCGAGCTCCTGACCTCAGGTGATCCTCCCACCTCGGC
CTCCCAAAGTTCTGGGATTACAGGGGTGAGCCACTGTGCCCGGCCATAATTTTATATTTTTAGAAAATAAAGAATGAAGGACAAAAGAGC
ACAGCTAAATGAAACTGCTGCTCTAATTTATTCCACTGGAAAGGTCTCAGGACTCCTTAACTGTTTTCCAGGTTTGGCTCTTCATATCTA
ACCTGTGCTAAAATGAGAAGGTATGCTAGGTGCTGTTAGAAATCACACCATTTCCAAAGAACCCAAGTAGTATAGAGACCAAAATGAGGC
AAAAATAAAAGAGATGAAACAGGAGAGTTTATTTCTTGCATACTTTCCGACCTTCATCATACAACCTCTCCTAACCTCCCTGTAGTCTTT
AAAATGTTTAACTTGCCTATAAGCTAACATGTAATAAAACACATACTCAATTATATGAATAGAAGTGGAGAGCCAGAATGCTACAAAAGA
AATCACAGCTGCTAGAAGTATCCTCCATAGAAACATCAACATGATTGTGGATCAAAATGATTTTCACTGGATATGGAATTTGTATGGGCC
ATATTTATTAAAAGAGTTCTGTGTGGTCACATAGAGTTCCTTTGGGATTTCATCCCACTTTTCAGGACTTAATTTGTTTGGGTTTGCTTA
CCTAACAAGCAACAACAACAACAAAATAAATAGTTCCAAAATCTAGTTTATTACATAAATCTCTATGAATCCTTGAGGGCCTATATCTAT
ATTATAAATAAATACAAATATAGATTTTTAAATATCTATGGGACTTTGCCATTTACAGCCTTAAGTATAAAATTACGAGATTATATTCTT
TCCATTACCCTTTATTTCTGCTAACTTTTTAAAGACTGGAACATTCTGTGGATGTTGTCAAAGTTTGAGTTTGTTTTTCCCTGTGTATTA

>63723_63723_1_PDE4D-ELOVL7_PDE4D_chr5_59481384_ENST00000546160_ELOVL7_chr5_60050660_ENST00000505959_length(amino acids)=89AA_BP=

--------------------------------------------------------------
>63723_63723_2_PDE4D-ELOVL7_PDE4D_chr5_59481384_ENST00000546160_ELOVL7_chr5_60050660_ENST00000508821_length(transcript)=3085nt_BP=42nt
ATGAAAAGAAATACCTGTGATTTGCTTTCTCGGAGCAAAAGTGTCCAGTTTGTTATTGTCGCCATCCACATAAGCCAGTTCTTTTTCATG
GAGGATTGCAAGTATCAGTTTCCAGTCTTTGCGTGCATCATTATGAGTTACAGTTTCATGTTTCTGCTGCTCTTTCTCCATTTTTGGTAC
CGTGCTTACACCAAAGGTCAGAGGTTGCCCAAAACTGTGAAAAATGGAACTTGCAAAAACAAAGATAATTGAAGCCCAACATAAGTCTAT
GATCGAAACTGATACATTGTCTTCCTTGACAATCAAGAGATATTTACCTATGCAGTGCATTTTGTATATTTTTCAAAACTAAGAGCTTGT
ATTTTTATGGTAAGTTATTGGGATGTCTGATATTTGAGAGCCCGAAGCTTCCAGATAACAGTCTTCTGATAATTAGAGCCTACAGCAGCC
AGAATTTGTTTTTGTTTTTGTTTTTGTTTTTTTAGCTGCTTTTAAACCTAATCCAAAGGTTTTGTTTAAAACATTTTGTTGCAGTGAAAA
AAAGATATGAAGCAATACAGTACTCTTCAAAGAAGTCCAATAAAGATGAAAAATATCATTAGGTATTTTGAGCACAGACGGAGATCCATG
TGATAAAATAGATTCCTTCTGCTGGGTCTGGAAAGTCTGGAAACCACCTGTAGGCCCTGGCTTTGTCATTTATTGACTGTATTCAGAAGA
TACTATATTTGCTCTAGAGTTAACTCCCATTTTAGCAAGCTAGCACAGGTGAAAATTGAGTGAGTTTTTGATAACTTGTCATTTAAAATC
ATTAATGATAATTTTCAATGGATCTTTTCAGTAGCCATCACCAGTTTTGCTGATAAGACTTCCTCACAACCCATTTGTTGTACAAACTGT
TTCAAAGTAGCAATCCTTTGGGTTAGTACACTTGATACCAAGTTTCATTCAGTTGATTATTTTCAAAACAAGGTGATTTGTTTTAATGGG
TTAATGAATACTTTGCTATTACTGTTTTACAATTAACTTTGTATATCTCTGGAAAGAGGTGAATTTGTCAATGAAAAAAGTATTGTGTAG
TTCAGTGGGAAAAACCTGTTGTCTGTTATAGTATCACATCACTTTCTTACATTGTCATGGTTTAAATTATTATCTTGGTGAAATATATAG
GTTAGATACTTAAATGTTCATATTATTAGCACACTACAGGTACTACCCTTAAATCATAAATAATATTACCCATTGTACACAGTTTCCAGA
TATGAGTTAGAGTGGCTGTGAAGCAACTAGAGGCAAATTGTGGCACAGAGAATATCCAGGGGAAAATTGATTATGTAAGCAAGGGCTGTT
CTACTTTGAGAGAGAGACAGACAGACTACATAATAGTAATATATTATATAATTAATGTTATAGATACACTGAACAATAAAACATTTTCTG
GAATTATGAATTAATTAACAACCTGGATTTCTGTTTCCAGACCTATAAACCATGTAATGAAGGACTGAAATTCGTTTGGCATACACTTTG
TTTCTTTAAAATTGCTAGTTTCTTTCTGTTATTTTTACATTTTCTTGTCAGAGAATCAAAACTATTAGTCAGTAGAGTTTTGTCCATGAA
ATAATATTTGGACATTTGTGAATTTTTCCCTATTTTTTTTCTTCTTTTATTTATACTCAATTTTGAAGCACTGTTTATGTTTGTAGGACT
TTAAACAATTAGTACTTAAAGCCCCAGTTAATTTTGAACACACAGAGATACTTATTGTACTCTGTGTACAGTAAGTATTTTTATGTTTAC
ACTTACCAGATTCATAAGGTTATTTGCCTTTAAGTGATCTTTTGTGATTTTACTTGATTACAGCATGAGAAGGTAAAGGTTGATAAATGG
GAGTAATTACATATATATATATAATTTATTATTTTTTTTTCTGAAGCAGAGTTTTACTCTTGTTGCCCAGGCTAGAGTGCAATGGCACAA
TCTCGGTTCACTGCAACCTCTGCCTCCCAGGTTCAAGTGATTCTCCTGTCTCAGCCTCCCAAGTAGCTGGGATTACAGGTGCCCGCCACC
ATGCTCAGCTAATTTTTGTATTTTTAGTAGAGACAGGGTTGGCCAGGCTGGTCTCGAGCTCCTGACCTCAGGTGATCCTCCCACCTCGGC
CTCCCAAAGTTCTGGGATTACAGGGGTGAGCCACTGTGCCCGGCCATAATTTTATATTTTTAGAAAATAAAGAATGAAGGACAAAAGAGC
ACAGCTAAATGAAACTGCTGCTCTAATTTATTCCACTGGAAAGGTCTCAGGACTCCTTAACTGTTTTCCAGGTTTGGCTCTTCATATCTA
ACCTGTGCTAAAATGAGAAGGTATGCTAGGTGCTGTTAGAAATCACACCATTTCCAAAGAACCCAAGTAGTATAGAGACCAAAATGAGGC
AAAAATAAAAGAGATGAAACAGGAGAGTTTATTTCTTGCATACTTTCCGACCTTCATCATACAACCTCTCCTAACCTCCCTGTAGTCTTT
AAAATGTTTAACTTGCCTATAAGCTAACATGTAATAAAACACATACTCAATTATATGAATAGAAGTGGAGAGCCAGAATGCTACAAAAGA
AATCACAGCTGCTAGAAGTATCCTCCATAGAAACATCAACATGATTGTGGATCAAAATGATTTTCACTGGATATGGAATTTGTATGGGCC
ATATTTATTAAAAGAGTTCTGTGTGGTCACATAGAGTTCCTTTGGGATTTCATCCCACTTTTCAGGACTTAATTTGTTTGGGTTTGCTTA
CCTAACAAGCAACAACAACAACAAAATAAATAGTTCCAAAATCTAGTTTATTACATAAATCTCTATGAATCCTTGAGGGCCTATATCTAT
ATTATAAATAAATACAAATATAGATTTTTAAATATCTATGGGACTTTGCCATTTACAGCCTTAAGTATAAAATTACGAGATTATATTCTT
TCCATTACCCTTTATTTCTGCTAACTTTTTAAAGACTGGAACATTCTGTGGATGTTGTCAAAGTTTGAGTTTGTTTTTCCCTGTGTATTA

>63723_63723_2_PDE4D-ELOVL7_PDE4D_chr5_59481384_ENST00000546160_ELOVL7_chr5_60050660_ENST00000508821_length(amino acids)=110AA_BP=0
MHCIGKYLLIVKEDNVSVSIIDLCWASIIFVFASSIFHSFGQPLTFGVSTVPKMEKEQQKHETVTHNDARKDWKLILAILHEKELAYVDG

--------------------------------------------------------------

Top

Fusion Gene PPI Analysis for PDE4D-ELOVL7


check button Go to ChiPPI (Chimeric Protein-Protein interactions) to see the chimeric PPI interaction in

ChiPPI page.


check button Protein-protein interactors with each fusion partner protein in wild-type (BIOGRID-3.4.160)
HgeneHgene's interactorsTgeneTgene's interactors


check button - Retained PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenStill interaction with


check button - Lost PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


check button - Retained PPIs, but lost function due to frame-shift fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


Top

Related Drugs for PDE4D-ELOVL7


check button Drugs targeting genes involved in this fusion gene.
(DrugBank Version 5.1.8 2021-05-08)
PartnerGeneUniProtAccDrugBank IDDrug nameDrug activityDrug typeDrug status

Top

Related Diseases for PDE4D-ELOVL7


check button Diseases associated with fusion partners.
(DisGeNet 4.0)
PartnerGeneDisease IDDisease name# pubmedsSource