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Center for Computational Systems Medicine
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Fusion Gene Summary

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Fusion Gene ORF analysis

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Fusion Genomic Features

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Fusion Protein Features

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Fusion Gene Sequence

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Fusion Gene PPI analysis

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Related Drugs

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Related Diseases

Fusion gene:PDE4DIP-C1orf186 (FusionGDB2 ID:63729)

Fusion Gene Summary for PDE4DIP-C1orf186

check button Fusion gene summary
Fusion gene informationFusion gene name: PDE4DIP-C1orf186
Fusion gene ID: 63729
HgeneTgene
Gene symbol

PDE4DIP

C1orf186

Gene ID

9659

440712

Gene namephosphodiesterase 4D interacting proteinregulator of hemoglobinization and erythroid cell expansion
SynonymsCMYA2|MMGLC1orf186
Cytomap

1q21.2

1q32.1

Type of geneprotein-codingprotein-coding
Descriptionmyomegalincardiomyopathy-associated protein 2myomegalin/phosphodiesterase 4D interacting protein variant 8regulator of hemoglobinization and erythroid cell expansion proteinregulator of human erythroid cell expansionregulator of human erythroid cell expansion proteinuncharacterized protein C1orf186
Modification date2020031320200313
UniProtAcc..
Ensembl transtripts involved in fusion geneENST00000313382, ENST00000313431, 
ENST00000369349, ENST00000369351, 
ENST00000369354, ENST00000369356, 
ENST00000369359, ENST00000479408, 
ENST00000529945, ENST00000530740, 
ENST00000369345, ENST00000369347, 
ENST00000369348, ENST00000478649, 
ENST00000493130, ENST00000524974, 
ENST00000469540, ENST00000331555, 
Fusion gene scores* DoF score9 X 9 X 7=5674 X 4 X 4=64
# samples 94
** MAII scorelog2(9/567*10)=-2.65535182861255
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0		log2(4/64*10)=-0.678071905112638
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0
Context

PubMed: PDE4DIP [Title/Abstract] AND C1orf186 [Title/Abstract] AND fusion [Title/Abstract]

Most frequent breakpointPDE4DIP(144915445)-C1orf186(206239579), # samples:3
Anticipated loss of major functional domain due to fusion event.PDE4DIP-C1orf186 seems lost the major protein functional domain in Hgene partner, which is a CGC due to the frame-shifted ORF.
PDE4DIP-C1orf186 seems lost the major protein functional domain in Hgene partner, which is a essential gene due to the frame-shifted ORF.
* DoF score (Degree of Frequency) = # partners X # break points X # cancer types
** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10)

check button Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez
PartnerGeneGO IDGO termPubMed ID
HgenePDE4DIP

GO:1903358

regulation of Golgi organization

27666745


check buttonFusion gene breakpoints across PDE4DIP (5'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.
all structure

check buttonFusion gene breakpoints across C1orf186 (3'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.
all structure

check button Fusion gene information from two resources (ChiTars 5.0 and ChimerDB 4.0)
* All genome coordinats were lifted-over on hg19.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
SourceDiseaseSampleHgeneHchrHbpHstrandTgeneTchrTbpTstrand
ChimerDB4BRCATCGA-BH-A203-01APDE4DIPchr1

144915445

-C1orf186chr1

206239579

-
ChimerDB4BRCATCGA-BH-A203-01APDE4DIPchr1

144915445

+C1orf186chr1

206239579

+


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Fusion Gene ORF analysis for PDE4DIP-C1orf186

check button Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
ORFHenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrand
5CDS-intronENST00000313382ENST00000469540PDE4DIPchr1

144915445

+C1orf186chr1

206239579

+
5CDS-intronENST00000313431ENST00000469540PDE4DIPchr1

144915445

+C1orf186chr1

206239579

+
5CDS-intronENST00000369349ENST00000469540PDE4DIPchr1

144915445

+C1orf186chr1

206239579

+
5CDS-intronENST00000369351ENST00000469540PDE4DIPchr1

144915445

+C1orf186chr1

206239579

+
5CDS-intronENST00000369354ENST00000469540PDE4DIPchr1

144915445

+C1orf186chr1

206239579

+
5CDS-intronENST00000369356ENST00000469540PDE4DIPchr1

144915445

+C1orf186chr1

206239579

+
5CDS-intronENST00000369359ENST00000469540PDE4DIPchr1

144915445

+C1orf186chr1

206239579

+
5CDS-intronENST00000479408ENST00000469540PDE4DIPchr1

144915445

+C1orf186chr1

206239579

+
5CDS-intronENST00000529945ENST00000469540PDE4DIPchr1

144915445

+C1orf186chr1

206239579

+
5CDS-intronENST00000530740ENST00000469540PDE4DIPchr1

144915445

+C1orf186chr1

206239579

+
Frame-shiftENST00000479408ENST00000331555PDE4DIPchr1

144915445

+C1orf186chr1

206239579

+
In-frameENST00000313382ENST00000331555PDE4DIPchr1

144915445

+C1orf186chr1

206239579

+
In-frameENST00000313431ENST00000331555PDE4DIPchr1

144915445

+C1orf186chr1

206239579

+
In-frameENST00000369349ENST00000331555PDE4DIPchr1

144915445

+C1orf186chr1

206239579

+
In-frameENST00000369351ENST00000331555PDE4DIPchr1

144915445

+C1orf186chr1

206239579

+
In-frameENST00000369354ENST00000331555PDE4DIPchr1

144915445

+C1orf186chr1

206239579

+
In-frameENST00000369356ENST00000331555PDE4DIPchr1

144915445

+C1orf186chr1

206239579

+
In-frameENST00000369359ENST00000331555PDE4DIPchr1

144915445

+C1orf186chr1

206239579

+
In-frameENST00000529945ENST00000331555PDE4DIPchr1

144915445

+C1orf186chr1

206239579

+
In-frameENST00000530740ENST00000331555PDE4DIPchr1

144915445

+C1orf186chr1

206239579

+
intron-3CDSENST00000369345ENST00000331555PDE4DIPchr1

144915445

+C1orf186chr1

206239579

+
intron-3CDSENST00000369347ENST00000331555PDE4DIPchr1

144915445

+C1orf186chr1

206239579

+
intron-3CDSENST00000369348ENST00000331555PDE4DIPchr1

144915445

+C1orf186chr1

206239579

+
intron-3CDSENST00000478649ENST00000331555PDE4DIPchr1

144915445

+C1orf186chr1

206239579

+
intron-3CDSENST00000493130ENST00000331555PDE4DIPchr1

144915445

+C1orf186chr1

206239579

+
intron-3CDSENST00000524974ENST00000331555PDE4DIPchr1

144915445

+C1orf186chr1

206239579

+
intron-intronENST00000369345ENST00000469540PDE4DIPchr1

144915445

+C1orf186chr1

206239579

+
intron-intronENST00000369347ENST00000469540PDE4DIPchr1

144915445

+C1orf186chr1

206239579

+
intron-intronENST00000369348ENST00000469540PDE4DIPchr1

144915445

+C1orf186chr1

206239579

+
intron-intronENST00000478649ENST00000469540PDE4DIPchr1

144915445

+C1orf186chr1

206239579

+
intron-intronENST00000493130ENST00000469540PDE4DIPchr1

144915445

+C1orf186chr1

206239579

+
intron-intronENST00000524974ENST00000469540PDE4DIPchr1

144915445

+C1orf186chr1

206239579

+

check buttonORFfinder result based on the fusion transcript sequence of in-frame fusion genes.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandSeq length
(transcript)		BP loci
(transcript)		Predicted start
(transcript)		Predicted stop
(transcript)		Seq length
(amino acids)
ENST00000313382PDE4DIPchr1144915445+ENST00000331555C1orf186chr1206239579+327925712972771824
ENST00000369354PDE4DIPchr1144915445+ENST00000331555C1orf186chr1206239579+287821701062370754
ENST00000369356PDE4DIPchr1144915445+ENST00000331555C1orf186chr1206239579+297922712072471754
ENST00000530740PDE4DIPchr1144915445+ENST00000331555C1orf186chr1206239579+31382430392630863
ENST00000369359PDE4DIPchr1144915445+ENST00000331555C1orf186chr1206239579+31382430392630863
ENST00000369351PDE4DIPchr1144915445+ENST00000331555C1orf186chr1206239579+27972089252289754
ENST00000369349PDE4DIPchr1144915445+ENST00000331555C1orf186chr1206239579+28332125612325754
ENST00000313431PDE4DIPchr1144915445+ENST00000331555C1orf186chr1206239579+383431266573326889
ENST00000529945PDE4DIPchr1144915445+ENST00000331555C1orf186chr1206239579+361729094403109889

check buttonDeepORF prediction of the coding potential based on the fusion transcript sequence of in-frame fusion genes. DeepORF is a coding potential classifier based on convolutional neural network by comparing the real Ribo-seq data. If the no-coding score < 0.5 and coding score > 0.5, then the in-frame fusion transcript is predicted as being likely translated.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandNo-coding scoreCoding score
ENST00000313382ENST00000331555PDE4DIPchr1144915445+C1orf186chr1206239579+0.0220704970.97792953
ENST00000369354ENST00000331555PDE4DIPchr1144915445+C1orf186chr1206239579+0.0152983860.98470163
ENST00000369356ENST00000331555PDE4DIPchr1144915445+C1orf186chr1206239579+0.0134586060.9865414
ENST00000530740ENST00000331555PDE4DIPchr1144915445+C1orf186chr1206239579+0.0103153380.9896847
ENST00000369359ENST00000331555PDE4DIPchr1144915445+C1orf186chr1206239579+0.0103153380.9896847
ENST00000369351ENST00000331555PDE4DIPchr1144915445+C1orf186chr1206239579+0.016610820.9833892
ENST00000369349ENST00000331555PDE4DIPchr1144915445+C1orf186chr1206239579+0.0149817940.9850182
ENST00000313431ENST00000331555PDE4DIPchr1144915445+C1orf186chr1206239579+0.0037234560.99627656
ENST00000529945ENST00000331555PDE4DIPchr1144915445+C1orf186chr1206239579+0.0034803050.9965197

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Fusion Genomic Features for PDE4DIP-C1orf186


check buttonFusionAI prediction of the potential fusion gene breakpoint based on the pre-mature RNA sequence context (+/- 5kb of individual partner genes, total 20kb length sequence). FusionAI is a fusion gene breakpoint classifier based on convolutional neural network by comparing the fusion positive and negative sequence context of ~ 20K fusion gene data. From here, we can have the relative potentency of the 20K genomic sequence how individual sequnce will be likely used as the gene fusion breakpoints.
HgeneHchrHbpHstrandTgeneTchrTbpTstrand1-pp (fusion gene breakpoint)

check buttonDistribution of 44 human genomic features loci across 20kb length fusion breakpoint regions. We integrated a total of 44 different types of human genomic feature loci information across five big categories including virus integration sites, repeats, structural variants, chromatin states, and gene expression regulation. More details are in help page.
genomic feature

check buttonDistribution of 44 human genomic features loci across 20kb length fusion breakpoint regions that are ovelapped with the top 1% feature importance score regions. More details are in help page.

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Fusion Protein Features for PDE4DIP-C1orf186


check button Four levels of functional features of fusion genes
Go to FGviewer search page for the most frequent breakpoint (https://ccsmweb.uth.edu/FGviewer/chr1:144915445/chr1:206239579)
- FGviewer provides the online visualization of the retention search of the protein functional features across DNA, RNA, protein, and pathological levels.
- How to search
1. Put your fusion gene symbol.
2. Press the tab key until there will be shown the breakpoint information filled.
4. Go down and press 'Search' tab twice.
4. Go down to have the hyperlink of the search result.
5. Click the hyperlink.
6. See the FGviewer result for your fusion gene.
FGviewer

check buttonMain function of each fusion partner protein. (from UniProt)
HgeneTgene
..
FUNCTION: Transcriptional activator which is required for calcium-dependent dendritic growth and branching in cortical neurons. Recruits CREB-binding protein (CREBBP) to nuclear bodies. Component of the CREST-BRG1 complex, a multiprotein complex that regulates promoter activation by orchestrating a calcium-dependent release of a repressor complex and a recruitment of an activator complex. In resting neurons, transcription of the c-FOS promoter is inhibited by BRG1-dependent recruitment of a phospho-RB1-HDAC1 repressor complex. Upon calcium influx, RB1 is dephosphorylated by calcineurin, which leads to release of the repressor complex. At the same time, there is increased recruitment of CREBBP to the promoter by a CREST-dependent mechanism, which leads to transcriptional activation. The CREST-BRG1 complex also binds to the NR2B promoter, and activity-dependent induction of NR2B expression involves a release of HDAC1 and recruitment of CREBBP (By similarity). {ECO:0000250}.FUNCTION: Transcriptional activator which is required for calcium-dependent dendritic growth and branching in cortical neurons. Recruits CREB-binding protein (CREBBP) to nuclear bodies. Component of the CREST-BRG1 complex, a multiprotein complex that regulates promoter activation by orchestrating a calcium-dependent release of a repressor complex and a recruitment of an activator complex. In resting neurons, transcription of the c-FOS promoter is inhibited by BRG1-dependent recruitment of a phospho-RB1-HDAC1 repressor complex. Upon calcium influx, RB1 is dephosphorylated by calcineurin, which leads to release of the repressor complex. At the same time, there is increased recruitment of CREBBP to the promoter by a CREST-dependent mechanism, which leads to transcriptional activation. The CREST-BRG1 complex also binds to the NR2B promoter, and activity-dependent induction of NR2B expression involves a release of HDAC1 and recruitment of CREBBP (By similarity). {ECO:0000250}.

check buttonRetention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at

download page


* Minus value of BPloci means that the break pointn is located before the CDS.
- In-frame and retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
HgenePDE4DIPchr1:144915445chr1:206239579ENST00000313382+1746162_2057262241.0Coiled coilOntology_term=ECO:0000255
HgenePDE4DIPchr1:144915445chr1:206239579ENST00000313382+1746238_3187262241.0Coiled coilOntology_term=ECO:0000255
HgenePDE4DIPchr1:144915445chr1:206239579ENST00000313382+1746350_6847262241.0Coiled coilOntology_term=ECO:0000255
HgenePDE4DIPchr1:144915445chr1:206239579ENST00000313382+174641_1327262241.0Coiled coilOntology_term=ECO:0000255
HgenePDE4DIPchr1:144915445chr1:206239579ENST00000313431+1019162_2058231133.0Coiled coilOntology_term=ECO:0000255
HgenePDE4DIPchr1:144915445chr1:206239579ENST00000313431+1019238_3188231133.0Coiled coilOntology_term=ECO:0000255
HgenePDE4DIPchr1:144915445chr1:206239579ENST00000313431+1019350_6848231133.0Coiled coilOntology_term=ECO:0000255
HgenePDE4DIPchr1:144915445chr1:206239579ENST00000313431+101941_1328231133.0Coiled coilOntology_term=ECO:0000255
HgenePDE4DIPchr1:144915445chr1:206239579ENST00000369349+1423162_205660970.0Coiled coilOntology_term=ECO:0000255
HgenePDE4DIPchr1:144915445chr1:206239579ENST00000369349+1423238_318660970.0Coiled coilOntology_term=ECO:0000255
HgenePDE4DIPchr1:144915445chr1:206239579ENST00000369349+142341_132660970.0Coiled coilOntology_term=ECO:0000255
HgenePDE4DIPchr1:144915445chr1:206239579ENST00000369351+1422162_205660989.0Coiled coilOntology_term=ECO:0000255
HgenePDE4DIPchr1:144915445chr1:206239579ENST00000369351+1422238_318660989.0Coiled coilOntology_term=ECO:0000255
HgenePDE4DIPchr1:144915445chr1:206239579ENST00000369351+142241_132660989.0Coiled coilOntology_term=ECO:0000255
HgenePDE4DIPchr1:144915445chr1:206239579ENST00000369354+1444162_2056602347.0Coiled coilOntology_term=ECO:0000255
HgenePDE4DIPchr1:144915445chr1:206239579ENST00000369354+1444238_3186602347.0Coiled coilOntology_term=ECO:0000255
HgenePDE4DIPchr1:144915445chr1:206239579ENST00000369354+144441_1326602347.0Coiled coilOntology_term=ECO:0000255
HgenePDE4DIPchr1:144915445chr1:206239579ENST00000369356+1444162_2056602363.0Coiled coilOntology_term=ECO:0000255
HgenePDE4DIPchr1:144915445chr1:206239579ENST00000369356+1444238_3186602363.0Coiled coilOntology_term=ECO:0000255
HgenePDE4DIPchr1:144915445chr1:206239579ENST00000369356+144441_1326602363.0Coiled coilOntology_term=ECO:0000255

- In-frame and not-retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
HgenePDE4DIPchr1:144915445chr1:206239579ENST00000313382+17461002_10437262241.0Coiled coilOntology_term=ECO:0000255
HgenePDE4DIPchr1:144915445chr1:206239579ENST00000313382+17461096_11247262241.0Coiled coilOntology_term=ECO:0000255
HgenePDE4DIPchr1:144915445chr1:206239579ENST00000313382+17461212_12407262241.0Coiled coilOntology_term=ECO:0000255
HgenePDE4DIPchr1:144915445chr1:206239579ENST00000313382+17461346_13857262241.0Coiled coilOntology_term=ECO:0000255
HgenePDE4DIPchr1:144915445chr1:206239579ENST00000313382+17461431_14557262241.0Coiled coilOntology_term=ECO:0000255
HgenePDE4DIPchr1:144915445chr1:206239579ENST00000313382+17461736_17607262241.0Coiled coilOntology_term=ECO:0000255
HgenePDE4DIPchr1:144915445chr1:206239579ENST00000313382+17461840_20777262241.0Coiled coilOntology_term=ECO:0000255
HgenePDE4DIPchr1:144915445chr1:206239579ENST00000313382+17462273_23127262241.0Coiled coilOntology_term=ECO:0000255
HgenePDE4DIPchr1:144915445chr1:206239579ENST00000313382+1746743_9367262241.0Coiled coilOntology_term=ECO:0000255
HgenePDE4DIPchr1:144915445chr1:206239579ENST00000313431+10191002_10438231133.0Coiled coilOntology_term=ECO:0000255
HgenePDE4DIPchr1:144915445chr1:206239579ENST00000313431+10191096_11248231133.0Coiled coilOntology_term=ECO:0000255
HgenePDE4DIPchr1:144915445chr1:206239579ENST00000313431+10191212_12408231133.0Coiled coilOntology_term=ECO:0000255
HgenePDE4DIPchr1:144915445chr1:206239579ENST00000313431+10191346_13858231133.0Coiled coilOntology_term=ECO:0000255
HgenePDE4DIPchr1:144915445chr1:206239579ENST00000313431+10191431_14558231133.0Coiled coilOntology_term=ECO:0000255
HgenePDE4DIPchr1:144915445chr1:206239579ENST00000313431+10191736_17608231133.0Coiled coilOntology_term=ECO:0000255
HgenePDE4DIPchr1:144915445chr1:206239579ENST00000313431+10191840_20778231133.0Coiled coilOntology_term=ECO:0000255
HgenePDE4DIPchr1:144915445chr1:206239579ENST00000313431+10192273_23128231133.0Coiled coilOntology_term=ECO:0000255
HgenePDE4DIPchr1:144915445chr1:206239579ENST00000313431+1019743_9368231133.0Coiled coilOntology_term=ECO:0000255
HgenePDE4DIPchr1:144915445chr1:206239579ENST00000369347+141002_10430174.0Coiled coilOntology_term=ECO:0000255
HgenePDE4DIPchr1:144915445chr1:206239579ENST00000369347+141096_11240174.0Coiled coilOntology_term=ECO:0000255
HgenePDE4DIPchr1:144915445chr1:206239579ENST00000369347+141212_12400174.0Coiled coilOntology_term=ECO:0000255
HgenePDE4DIPchr1:144915445chr1:206239579ENST00000369347+141346_13850174.0Coiled coilOntology_term=ECO:0000255
HgenePDE4DIPchr1:144915445chr1:206239579ENST00000369347+141431_14550174.0Coiled coilOntology_term=ECO:0000255
HgenePDE4DIPchr1:144915445chr1:206239579ENST00000369347+14162_2050174.0Coiled coilOntology_term=ECO:0000255
HgenePDE4DIPchr1:144915445chr1:206239579ENST00000369347+141736_17600174.0Coiled coilOntology_term=ECO:0000255
HgenePDE4DIPchr1:144915445chr1:206239579ENST00000369347+141840_20770174.0Coiled coilOntology_term=ECO:0000255
HgenePDE4DIPchr1:144915445chr1:206239579ENST00000369347+142273_23120174.0Coiled coilOntology_term=ECO:0000255
HgenePDE4DIPchr1:144915445chr1:206239579ENST00000369347+14238_3180174.0Coiled coilOntology_term=ECO:0000255
HgenePDE4DIPchr1:144915445chr1:206239579ENST00000369347+14350_6840174.0Coiled coilOntology_term=ECO:0000255
HgenePDE4DIPchr1:144915445chr1:206239579ENST00000369347+1441_1320174.0Coiled coilOntology_term=ECO:0000255
HgenePDE4DIPchr1:144915445chr1:206239579ENST00000369347+14743_9360174.0Coiled coilOntology_term=ECO:0000255
HgenePDE4DIPchr1:144915445chr1:206239579ENST00000369348+171002_10430311.0Coiled coilOntology_term=ECO:0000255
HgenePDE4DIPchr1:144915445chr1:206239579ENST00000369348+171096_11240311.0Coiled coilOntology_term=ECO:0000255
HgenePDE4DIPchr1:144915445chr1:206239579ENST00000369348+171212_12400311.0Coiled coilOntology_term=ECO:0000255
HgenePDE4DIPchr1:144915445chr1:206239579ENST00000369348+171346_13850311.0Coiled coilOntology_term=ECO:0000255
HgenePDE4DIPchr1:144915445chr1:206239579ENST00000369348+171431_14550311.0Coiled coilOntology_term=ECO:0000255
HgenePDE4DIPchr1:144915445chr1:206239579ENST00000369348+17162_2050311.0Coiled coilOntology_term=ECO:0000255
HgenePDE4DIPchr1:144915445chr1:206239579ENST00000369348+171736_17600311.0Coiled coilOntology_term=ECO:0000255
HgenePDE4DIPchr1:144915445chr1:206239579ENST00000369348+171840_20770311.0Coiled coilOntology_term=ECO:0000255
HgenePDE4DIPchr1:144915445chr1:206239579ENST00000369348+172273_23120311.0Coiled coilOntology_term=ECO:0000255
HgenePDE4DIPchr1:144915445chr1:206239579ENST00000369348+17238_3180311.0Coiled coilOntology_term=ECO:0000255
HgenePDE4DIPchr1:144915445chr1:206239579ENST00000369348+17350_6840311.0Coiled coilOntology_term=ECO:0000255
HgenePDE4DIPchr1:144915445chr1:206239579ENST00000369348+1741_1320311.0Coiled coilOntology_term=ECO:0000255
HgenePDE4DIPchr1:144915445chr1:206239579ENST00000369348+17743_9360311.0Coiled coilOntology_term=ECO:0000255
HgenePDE4DIPchr1:144915445chr1:206239579ENST00000369349+14231002_1043660970.0Coiled coilOntology_term=ECO:0000255
HgenePDE4DIPchr1:144915445chr1:206239579ENST00000369349+14231096_1124660970.0Coiled coilOntology_term=ECO:0000255
HgenePDE4DIPchr1:144915445chr1:206239579ENST00000369349+14231212_1240660970.0Coiled coilOntology_term=ECO:0000255
HgenePDE4DIPchr1:144915445chr1:206239579ENST00000369349+14231346_1385660970.0Coiled coilOntology_term=ECO:0000255
HgenePDE4DIPchr1:144915445chr1:206239579ENST00000369349+14231431_1455660970.0Coiled coilOntology_term=ECO:0000255
HgenePDE4DIPchr1:144915445chr1:206239579ENST00000369349+14231736_1760660970.0Coiled coilOntology_term=ECO:0000255
HgenePDE4DIPchr1:144915445chr1:206239579ENST00000369349+14231840_2077660970.0Coiled coilOntology_term=ECO:0000255
HgenePDE4DIPchr1:144915445chr1:206239579ENST00000369349+14232273_2312660970.0Coiled coilOntology_term=ECO:0000255
HgenePDE4DIPchr1:144915445chr1:206239579ENST00000369349+1423350_684660970.0Coiled coilOntology_term=ECO:0000255
HgenePDE4DIPchr1:144915445chr1:206239579ENST00000369349+1423743_936660970.0Coiled coilOntology_term=ECO:0000255
HgenePDE4DIPchr1:144915445chr1:206239579ENST00000369351+14221002_1043660989.0Coiled coilOntology_term=ECO:0000255
HgenePDE4DIPchr1:144915445chr1:206239579ENST00000369351+14221096_1124660989.0Coiled coilOntology_term=ECO:0000255
HgenePDE4DIPchr1:144915445chr1:206239579ENST00000369351+14221212_1240660989.0Coiled coilOntology_term=ECO:0000255
HgenePDE4DIPchr1:144915445chr1:206239579ENST00000369351+14221346_1385660989.0Coiled coilOntology_term=ECO:0000255
HgenePDE4DIPchr1:144915445chr1:206239579ENST00000369351+14221431_1455660989.0Coiled coilOntology_term=ECO:0000255
HgenePDE4DIPchr1:144915445chr1:206239579ENST00000369351+14221736_1760660989.0Coiled coilOntology_term=ECO:0000255
HgenePDE4DIPchr1:144915445chr1:206239579ENST00000369351+14221840_2077660989.0Coiled coilOntology_term=ECO:0000255
HgenePDE4DIPchr1:144915445chr1:206239579ENST00000369351+14222273_2312660989.0Coiled coilOntology_term=ECO:0000255
HgenePDE4DIPchr1:144915445chr1:206239579ENST00000369351+1422350_684660989.0Coiled coilOntology_term=ECO:0000255
HgenePDE4DIPchr1:144915445chr1:206239579ENST00000369351+1422743_936660989.0Coiled coilOntology_term=ECO:0000255
HgenePDE4DIPchr1:144915445chr1:206239579ENST00000369354+14441002_10436602347.0Coiled coilOntology_term=ECO:0000255
HgenePDE4DIPchr1:144915445chr1:206239579ENST00000369354+14441096_11246602347.0Coiled coilOntology_term=ECO:0000255
HgenePDE4DIPchr1:144915445chr1:206239579ENST00000369354+14441212_12406602347.0Coiled coilOntology_term=ECO:0000255
HgenePDE4DIPchr1:144915445chr1:206239579ENST00000369354+14441346_13856602347.0Coiled coilOntology_term=ECO:0000255
HgenePDE4DIPchr1:144915445chr1:206239579ENST00000369354+14441431_14556602347.0Coiled coilOntology_term=ECO:0000255
HgenePDE4DIPchr1:144915445chr1:206239579ENST00000369354+14441736_17606602347.0Coiled coilOntology_term=ECO:0000255
HgenePDE4DIPchr1:144915445chr1:206239579ENST00000369354+14441840_20776602347.0Coiled coilOntology_term=ECO:0000255
HgenePDE4DIPchr1:144915445chr1:206239579ENST00000369354+14442273_23126602347.0Coiled coilOntology_term=ECO:0000255
HgenePDE4DIPchr1:144915445chr1:206239579ENST00000369354+1444350_6846602347.0Coiled coilOntology_term=ECO:0000255
HgenePDE4DIPchr1:144915445chr1:206239579ENST00000369354+1444743_9366602347.0Coiled coilOntology_term=ECO:0000255
HgenePDE4DIPchr1:144915445chr1:206239579ENST00000369356+14441002_10436602363.0Coiled coilOntology_term=ECO:0000255
HgenePDE4DIPchr1:144915445chr1:206239579ENST00000369356+14441096_11246602363.0Coiled coilOntology_term=ECO:0000255
HgenePDE4DIPchr1:144915445chr1:206239579ENST00000369356+14441212_12406602363.0Coiled coilOntology_term=ECO:0000255
HgenePDE4DIPchr1:144915445chr1:206239579ENST00000369356+14441346_13856602363.0Coiled coilOntology_term=ECO:0000255
HgenePDE4DIPchr1:144915445chr1:206239579ENST00000369356+14441431_14556602363.0Coiled coilOntology_term=ECO:0000255
HgenePDE4DIPchr1:144915445chr1:206239579ENST00000369356+14441736_17606602363.0Coiled coilOntology_term=ECO:0000255
HgenePDE4DIPchr1:144915445chr1:206239579ENST00000369356+14441840_20776602363.0Coiled coilOntology_term=ECO:0000255
HgenePDE4DIPchr1:144915445chr1:206239579ENST00000369356+14442273_23126602363.0Coiled coilOntology_term=ECO:0000255
HgenePDE4DIPchr1:144915445chr1:206239579ENST00000369356+1444350_6846602363.0Coiled coilOntology_term=ECO:0000255
HgenePDE4DIPchr1:144915445chr1:206239579ENST00000369356+1444743_9366602363.0Coiled coilOntology_term=ECO:0000255
HgenePDE4DIPchr1:144915445chr1:206239579ENST00000313382+17461551_16427262241.0DomainOlduvai
HgenePDE4DIPchr1:144915445chr1:206239579ENST00000313431+10191551_16428231133.0DomainOlduvai
HgenePDE4DIPchr1:144915445chr1:206239579ENST00000369347+141551_16420174.0DomainOlduvai
HgenePDE4DIPchr1:144915445chr1:206239579ENST00000369348+171551_16420311.0DomainOlduvai
HgenePDE4DIPchr1:144915445chr1:206239579ENST00000369349+14231551_1642660970.0DomainOlduvai
HgenePDE4DIPchr1:144915445chr1:206239579ENST00000369351+14221551_1642660989.0DomainOlduvai
HgenePDE4DIPchr1:144915445chr1:206239579ENST00000369354+14441551_16426602347.0DomainOlduvai
HgenePDE4DIPchr1:144915445chr1:206239579ENST00000369356+14441551_16426602363.0DomainOlduvai
TgeneC1orf186chr1:144915445chr1:206239579ENST00000331555469_29106173.0TransmembraneHelical


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Fusion Gene Sequence for PDE4DIP-C1orf186


check button For in-frame fusion transcripts, we provide the fusion transcript sequences and fusion amino acid sequences. To have fusion amino acid sequence, we ran ORFfinder and chose the longest ORF among the all predicted ones.
>63729_63729_1_PDE4DIP-C1orf186_PDE4DIP_chr1_144915445_ENST00000313382_C1orf186_chr1_206239579_ENST00000331555_length(transcript)=3279nt_BP=2571nt
GCTCGCGGTTGACAGCTCAGCTGGTGCCGAGCAACTCGTGCCAGCCAGTCGTGTCTCAGCCTGGAGAGTGCGCGCACCGCCGCCCGGGCA
GCCGCTGGCTCCAGCTCACGAAACAGCCCCGGGCGCCGCGCCGCTCTGAGTCCAGCCTCCTACTGAGAACAGTCCCTCCCTTGTGCGGGT
CGCACGGCTAGCCGCAGGTTCGGCCACGTCAAATCCATTTTCTAAAAAAGCAGGGAGCAGAGCTCTCTCTTCGCCGCCGACGCAGAAAGG
AGCTGGGGAGGAAAAAGCTGCTGCCTTTTGCGCTGGAGATTCGTGGGCAAGGCTTCTCATTTTCCCAGGCTGCTTCCCCTCCCGGGTGAG
GAGCGTCCTGAGACTAAGGAAAGAGCCTGGAAAATGGAGCAGACCTGGACGAGAGATTATTTTGCAGAGGATGATGGGGAGATGGTACCC
AGAACGAGTCACACAGCAGCTTTTCTTAGTGACACTAAAGATCGAGGCCCTCCAGTGCAGTCACAGATCTGGAGAAGTGGTGAAAAGGTC
CCGTTTGTGCAGACATATTCCTTGAGAGCATTTGAGAAACCCCCTCAGGTACAGACCCAGGCTCTTCGAGACTTTGAGAAGCACCTCAAT
GACCTGAAGAAGGAGAACTTCAGCCTCAAGCTGCGCATCTACTTCCTGGAGGAGCGCATGCAACAGAAGTATGAGGCCAGCCGGGAGGAC
ATCTACAAGCGGAACATTGAGCTGAAGGTTGAAGTGGAGAGCTTGAAACGAGAACTCCAGGACAAGAAACAGCATCTGGATAAAACATGG
GCTGATGTGGAGAATCTCAACAGTCAGAATGAAGCTGAGCTCCGACGCCAGTTTGAGGAGCGACAGCAGGAGACGGAGCATGTTTATGAG
CTCTTGGAGAATAAGATCCAGCTTCTGCAGGAGGAATCCAGGCTAGCAAAGAATGAAGCTGCGCGGATGGCAGCTCTGGTGGAAGCAGAG
AAGGAGTGTAACCTGGAGCTCTCAGAGAAACTGAAGGGAGTCACCAAAAACTGGGAAGATGTACCAGGAGACCAGGTCAAGCCCGACCAA
TACACTGAGGCCCTGGCCCAGAGGGACAAGAGAATTGAAGAACTGAATCAGAGCCTGGCTGCCCAGGAGAGGCTTGTAGAACAGCTATCT
CGGGAGAAACAACAACTGCTACATCTGTTGGAGGAGCCAACTAGCATGGAAGTGCAGCCCATGACTGAAGAGTTGCTGAAACAACAAAAG
CTGAATTCACATGAGACCACTATAACTCAGCAGTCTGTATCTGATTCCCACTTGGCAGAACTCCAGGAAAAAATCCAGCAAACAGAGGCC
ACCAACAAGATTCTTCAAGAGAAACTTAATGAAATGAGCTATGAACTAAAGTGTGCTCAGGAGTCGTCTCAAAAGCAAGATGGTACAATT
CAGAACCTCAAGGAAACTCTGAAAAGCAGGGAACGTGAGACTGAGGAGTTGTACCAGGTAATTGAAGGTCAAAATGACACAATGGCAAAG
CTTCGAGAAATGCTGCACCAAAGCCAGCTTGGACAACTTCACAGCTCAGAGGGTACTTCTCCAGCTCAGCAACAGGTAGCTCTGCTTGAT
CTTCAGAGTGCTTTATTCTGCAGCCAACTTGAAATACAGAAGCTCCAGAGGGTGGTACGACAGAAAGAGCGCCAACTGGCTGATGCCAAA
CAATGTGTGCAATTTGTAGAGGCTGCAGCACACGAGAGTGAACAGCAGAAAGAGGCTTCTTGGAAACATAACCAGGAATTGCGAAAAGCC
TTGCAGCAGCTACAAGAAGAATTGCAGAATAAGAGCCAACAGCTTCGTGCCTGGGAGGCTGAAAAATACAATGAGATTCGAACCCAGGAA
CAAAACATCCAGCACCTAAACCATAGTCTGAGTCACAAGGAGCAGTTGCTTCAGGAATTTCGGGAGCTCCTACAGTATCGAGATAACTCA
GACAAAACCCTTGAAGCAAATGAAATGTTGCTTGAGAAACTTCGCCAGCGAATACATGATAAAGCTGTTGCTCTGGAGCGGGCTATAGAT
GAAAAATTCTCTGCTCTAGAAGAGAAAGAAAAAGAACTGCGCCAGCTTCGTCTTGCTGTGAGAGAGCGAGATCATGACTTAGAGAGACTG
CGCGATGTCCTCTCCTCCAATGAAGCTACTATGCAAAGTATGGAGAGTCTCCTGAGGGCCAAAGGCCTGGAAGTGGAACAGTTATCTACT
ACCTGTCAAAACCTCCAGTGGCTGAAAGAAGAAATGGAAACCAAATTTAGCCGTTGGCAGAAGGAACAAGAGAGTATCATTCAGCAGTTA
CAGACGTCTCTTCATGATAGGAACAAAGAAGTGGAGGATCTTAGTGCAACACTGCTCTGCAAACTTGGACCAGGGCAGAGTGAGATAGCA
GAGGAGCTGTGCCAGCGTCTACAGCGAAAGGAAAGGATGCTGCAGGACCTTCTAAGTGATCGAAATAAACAAGTGCTGGAACATGAAATG
GAGATTCAAGGCCTGCTTCAGTCTGTGAGCACCAGGGAGCAGGAAAGCCAAGCCACAGAGGATGTGGATTACACACAAGTCGTCTTTTCT
GACCCTGGAGAACTAAAAAATGACTCCCCGCTGGACTATGAGAACATAAAGGAAATCACAGATTATGTCAATGTCAATCCAGAAAGACAC
AAGCCCAGTTTCTGGTATTTTGTCAACCCTGCTCTGTCTGAGCCAGCGGAATATGATCAAGTGGCCATGTGAATTCCAAATATTTTTAAT
GGGGTCCAGTTCTCTATGGATTCTTACATTTAATTTGTAGGGAAATGCCATTTTTCCCCCTTAAACAAGGCATGGGGCTCACAAGTCTAT
GGAGACAGGCCAAAAAGAATGTGGAGAAGAAAACTGATAAATACACAGAGGTCCTCAAGACCCATGGACTCCTGGTCTGTACCCAAAAAA
GCTGTTCGTTCCTCAAAAACAAAAACAAGGCTTGGCTGGGAAAACAGGCCAATGCCCCGGCAAGAAAGGTTGAGATCAGATGTTAGGAAG
AACTTTCAGGTAAAGTATGAGAACTATGGAGTCCATCAGCAGAGATAGTAGTGAAGTCTCTCCCCAGGGAAAATTTTAAAAAGGTTGAAT
CAGCTGTTGTAGAGTTCTATTTGGCAATCTCATGGTTAAATGACTTCCCTTTGAGCTCTTTAATTATTGGCAATAAACAACTTCTTTAAA

>63729_63729_1_PDE4DIP-C1orf186_PDE4DIP_chr1_144915445_ENST00000313382_C1orf186_chr1_206239579_ENST00000331555_length(amino acids)=824AA_BP=758
MRWRFVGKASHFPRLLPLPGEERPETKERAWKMEQTWTRDYFAEDDGEMVPRTSHTAAFLSDTKDRGPPVQSQIWRSGEKVPFVQTYSLR
AFEKPPQVQTQALRDFEKHLNDLKKENFSLKLRIYFLEERMQQKYEASREDIYKRNIELKVEVESLKRELQDKKQHLDKTWADVENLNSQ
NEAELRRQFEERQQETEHVYELLENKIQLLQEESRLAKNEAARMAALVEAEKECNLELSEKLKGVTKNWEDVPGDQVKPDQYTEALAQRD
KRIEELNQSLAAQERLVEQLSREKQQLLHLLEEPTSMEVQPMTEELLKQQKLNSHETTITQQSVSDSHLAELQEKIQQTEATNKILQEKL
NEMSYELKCAQESSQKQDGTIQNLKETLKSRERETEELYQVIEGQNDTMAKLREMLHQSQLGQLHSSEGTSPAQQQVALLDLQSALFCSQ
LEIQKLQRVVRQKERQLADAKQCVQFVEAAAHESEQQKEASWKHNQELRKALQQLQEELQNKSQQLRAWEAEKYNEIRTQEQNIQHLNHS
LSHKEQLLQEFRELLQYRDNSDKTLEANEMLLEKLRQRIHDKAVALERAIDEKFSALEEKEKELRQLRLAVRERDHDLERLRDVLSSNEA
TMQSMESLLRAKGLEVEQLSTTCQNLQWLKEEMETKFSRWQKEQESIIQQLQTSLHDRNKEVEDLSATLLCKLGPGQSEIAEELCQRLQR
KERMLQDLLSDRNKQVLEHEMEIQGLLQSVSTREQESQATEDVDYTQVVFSDPGELKNDSPLDYENIKEITDYVNVNPERHKPSFWYFVN

--------------------------------------------------------------
>63729_63729_2_PDE4DIP-C1orf186_PDE4DIP_chr1_144915445_ENST00000313431_C1orf186_chr1_206239579_ENST00000331555_length(transcript)=3834nt_BP=3126nt
GGATCCTTGAGGGCACTGGTGCGACTTTCAGGTGAGGTCTTAGCAGATGAAAGCGGCTGGCTGTGGCCCGCGCCAGTAGTGCTTTCTGCT
CCGCACTCGCCGTGAGCCAGGTGTGCAACCGGATTTGGGGCGAGGGTCGCGCTGGCTACCTCGCATGCGCAGAGCCGGAAGCCCGCTGAC
CGGACTACAGCTCCCAGAAGAGCCTTGTGGAGGCCGCAGACGCGAAGCCGCTGGCGCCATCTTGAAATCTGATCCTCCATCCCCGAGGCT
TTGCGTCTGCGCGGCCGGCCGCTGCTGCTCCGGGAGCCCAGTCTGCTAAAAGGGGAGGACGTTGAGGACGCGGCGGCTGGCGGGAGAGAC
AGCTGGGGAGAGACATGGCAGGGTCGGAGCGCGGCCTGCGCCTCTGTCACTCAGCATCCTCTTAGGCGTTTCCACGCCCGCCCCCTGCCC
GAGGGGCGGGGCTGACGGCTCTGGTACCCGGAGTCGGCGCGCGGGGCAGGGGCGCGCCCCTGCAGAGTGGGGACCCCACTGGGCTGTGCC
ATGCTGACCGGAGACCACCGAGGCGGGAGACAGAGCGCGGCGAAGAGCCATTGAGTGGTCACCCAGTAGCCGCCGCCGCCGCCGCCTCGG
GAAGCTTGCCACCCGCTAGGAGGGAAGATGAAGGAGATTTGCAGGATCTGTGCCCGAGAGCTGTGTGGAAACCAGCGGCGCTGGATCTTC
CACACGGCGTCCAAGCTCAATCTCCAGGTTCTGCTTTCGCACGTCTTGGGCAAGGATGTCCCCCGCGATGGCAAAGCCGAGTTCGCTTGC
AGCAAGTGTGCTTTCATGCTTGATCGAATCTATCGATTCGACACAGTTATTGCCCGGATTGAAGCGCTTTCTATTGAGCGCTTGCAAAAG
CTGCTACTGGAGAAGGATCGCCTCAAGTTCTGCATTGCCAGTATGTATCGGAAGAATAACGATGACTCTGGCGCGGAGATCAAGGCGGGG
AATGGGACGGTTGACATGTCCGTCTTACCCGATGCGAGATACTCTGCACTGCTCCAGGAGGACTTCGCCTATTCAGGGTTTGAGTGCTGG
GTGGAGAATGAGGATCAGATCCAGGAGCCACACAGCTGCCATGGTTCAGAAGGCCCTGGAAACCGACCCAGGAGATGCCGTGGTTGTGCC
GCTTTGCGGGTTGCTGATTCTGACTATGAAGCCATTTGTAAGGTACCTCGAAAGGTGGCCAGAAGTATCTCCTGCGGCCCTTCTAGCAGG
TGGTCGACCAGCATTTGCACTGAAGAACCAGCGTTGTCTGAGGTTGGGCCACCCGACTTAGCAAGCACAAAGGTACCCCCAGATGGAGAA
AGCATGGAGGAAGAGACGCCTGGTTCCTCTGTGGAATCTTTGGATGCAAGCGTCCAGGCTAGCCCTCCACAACAGAAAGATGAGGAGACT
GAGAGAAGTGCAAAGGAACTTGGAAAGTGTGACTGTTGTTCAGATGATCAGGCTCCGCAGCATGGGTGTAATCACAAGCTGGAATTAGCT
CTTAGCATGATTAAAGGTCTTGATTATAAGCCCATCCAGAGCCCCCGAGGGAGCAGGCTTCCGATTCCAGTGAAATCCAGCCTACCTGGA
GCCAAGCCTGGCCCTAGCATGACAGATGGAGTTAGTTCCGGTTTCCTTAACAGGTCTTTGAAACCCCTTTACAAGACACCTGTGAGTTAT
CCCTTGGAGCTTTCAGACCTGCAGGAGCTGTGGGATGATCTCTGTGAAGATTATTTGCCGCTCCGGGTCCAGCCCATGACTGAAGAGTTG
CTGAAACAACAAAAGCTGAATTCACATGAGACCACTATAACTCAGCAGTCTGTATCTGATTCCCACTTGGCAGAACTCCAGGAAAAAATC
CAGCAAACAGAGGCCACCAACAAGATTCTTCAAGAGAAACTTAATGAAATGAGCTATGAACTAAAGTGTGCTCAGGAGTCGTCTCAAAAG
CAAGATGGTACAATTCAGAACCTCAAGGAAACTCTGAAAAGCAGGGAACGTGAGACTGAGGAGTTGTACCAGGTAATTGAAGGTCAAAAT
GACACAATGGCAAAGCTTCGAGAAATGCTGCACCAAAGCCAGCTTGGACAACTTCACAGCTCAGAGGGTACTTCTCCAGCTCAGCAACAG
GTAGCTCTGCTTGATCTTCAGAGTGCTTTATTCTGCAGCCAACTTGAAATACAGAAGCTCCAGAGGGTGGTACGACAGAAAGAGCGCCAA
CTGGCTGATGCCAAACAATGTGTGCAATTTGTAGAGGCTGCAGCACACGAGAGTGAACAGCAGAAAGAGGCTTCTTGGAAACATAACCAG
GAATTGCGAAAAGCCTTGCAGCAGCTACAAGAAGAATTGCAGAATAAGAGCCAACAGCTTCGTGCCTGGGAGGCTGAAAAATACAATGAG
ATTCGAACCCAGGAACAAAACATCCAGCACCTAAACCATAGTCTGAGTCACAAGGAGCAGTTGCTTCAGGAATTTCGGGAGCTCCTACAG
TATCGAGATAACTCAGACAAAACCCTTGAAGCAAATGAAATGTTGCTTGAGAAACTTCGCCAGCGAATACATGATAAAGCTGTTGCTCTG
GAGCGGGCTATAGATGAAAAATTCTCTGCTCTAGAAGAGAAAGAAAAAGAACTGCGCCAGCTTCGTCTTGCTGTGAGAGAGCGAGATCAT
GACTTAGAGAGACTGCGCGATGTCCTCTCCTCCAATGAAGCTACTATGCAAAGTATGGAGAGTCTCCTGAGGGCCAAAGGCCTGGAAGTG
GAACAGTTATCTACTACCTGTCAAAACCTCCAGTGGCTGAAAGAAGAAATGGAAACCAAATTTAGCCGTTGGCAGAAGGAACAAGAGAGT
ATCATTCAGCAGTTACAGACGTCTCTTCATGATAGGAACAAAGAAGTGGAGGATCTTAGTGCAACACTGCTCTGCAAACTTGGACCAGGG
CAGAGTGAGATAGCAGAGGAGCTGTGCCAGCGTCTACAGCGAAAGGAAAGGATGCTGCAGGACCTTCTAAGTGATCGAAATAAACAAGTG
CTGGAACATGAAATGGAGATTCAAGGCCTGCTTCAGTCTGTGAGCACCAGGGAGCAGGAAAGCCAAGCCACAGAGGATGTGGATTACACA
CAAGTCGTCTTTTCTGACCCTGGAGAACTAAAAAATGACTCCCCGCTGGACTATGAGAACATAAAGGAAATCACAGATTATGTCAATGTC
AATCCAGAAAGACACAAGCCCAGTTTCTGGTATTTTGTCAACCCTGCTCTGTCTGAGCCAGCGGAATATGATCAAGTGGCCATGTGAATT
CCAAATATTTTTAATGGGGTCCAGTTCTCTATGGATTCTTACATTTAATTTGTAGGGAAATGCCATTTTTCCCCCTTAAACAAGGCATGG
GGCTCACAAGTCTATGGAGACAGGCCAAAAAGAATGTGGAGAAGAAAACTGATAAATACACAGAGGTCCTCAAGACCCATGGACTCCTGG
TCTGTACCCAAAAAAGCTGTTCGTTCCTCAAAAACAAAAACAAGGCTTGGCTGGGAAAACAGGCCAATGCCCCGGCAAGAAAGGTTGAGA
TCAGATGTTAGGAAGAACTTTCAGGTAAAGTATGAGAACTATGGAGTCCATCAGCAGAGATAGTAGTGAAGTCTCTCCCCAGGGAAAATT
TTAAAAAGGTTGAATCAGCTGTTGTAGAGTTCTATTTGGCAATCTCATGGTTAAATGACTTCCCTTTGAGCTCTTTAATTATTGGCAATA

>63729_63729_2_PDE4DIP-C1orf186_PDE4DIP_chr1_144915445_ENST00000313431_C1orf186_chr1_206239579_ENST00000331555_length(amino acids)=889AA_BP=823
MKEICRICARELCGNQRRWIFHTASKLNLQVLLSHVLGKDVPRDGKAEFACSKCAFMLDRIYRFDTVIARIEALSIERLQKLLLEKDRLK
FCIASMYRKNNDDSGAEIKAGNGTVDMSVLPDARYSALLQEDFAYSGFECWVENEDQIQEPHSCHGSEGPGNRPRRCRGCAALRVADSDY
EAICKVPRKVARSISCGPSSRWSTSICTEEPALSEVGPPDLASTKVPPDGESMEEETPGSSVESLDASVQASPPQQKDEETERSAKELGK
CDCCSDDQAPQHGCNHKLELALSMIKGLDYKPIQSPRGSRLPIPVKSSLPGAKPGPSMTDGVSSGFLNRSLKPLYKTPVSYPLELSDLQE
LWDDLCEDYLPLRVQPMTEELLKQQKLNSHETTITQQSVSDSHLAELQEKIQQTEATNKILQEKLNEMSYELKCAQESSQKQDGTIQNLK
ETLKSRERETEELYQVIEGQNDTMAKLREMLHQSQLGQLHSSEGTSPAQQQVALLDLQSALFCSQLEIQKLQRVVRQKERQLADAKQCVQ
FVEAAAHESEQQKEASWKHNQELRKALQQLQEELQNKSQQLRAWEAEKYNEIRTQEQNIQHLNHSLSHKEQLLQEFRELLQYRDNSDKTL
EANEMLLEKLRQRIHDKAVALERAIDEKFSALEEKEKELRQLRLAVRERDHDLERLRDVLSSNEATMQSMESLLRAKGLEVEQLSTTCQN
LQWLKEEMETKFSRWQKEQESIIQQLQTSLHDRNKEVEDLSATLLCKLGPGQSEIAEELCQRLQRKERMLQDLLSDRNKQVLEHEMEIQG

--------------------------------------------------------------
>63729_63729_3_PDE4DIP-C1orf186_PDE4DIP_chr1_144915445_ENST00000369349_C1orf186_chr1_206239579_ENST00000331555_length(transcript)=2833nt_BP=2125nt
AGGGGCCATGTCGCCGTAGCCCCAGCCTCTCGGTCCGCAGCCTCAGCAGCGTCCCAGCCGGCTGGCTTCATGCTGCGGTGCAGCTGCACC
ATGTTCCTGGGTTGAGGGGGCAATCGGGCACGCTCCTCCCCATGGGTTGCCCATCATGTCTAATGGATATCGCACTCTGTCCCAGCACCT
CAATGACCTGAAGAAGGAGAACTTCAGCCTCAAGCTGCGCATCTACTTCCTGGAGGAGCGCATGCAACAGAAGTATGAGGCCAGCCGGGA
GGACATCTACAAGCGGAACATTGAGCTGAAGGTTGAAGTGGAGAGCTTGAAACGAGAACTCCAGGACAAGAAACAGCATCTGGATAAAAC
ATGGGCTGATGTGGAGAATCTCAACAGTCAGAATGAAGCTGAGCTCCGACGCCAGTTTGAGGAGCGACAGCAGGAGACGGAGCATGTTTA
TGAGCTCTTGGAGAATAAGATCCAGCTTCTGCAGGAGGAATCCAGGCTAGCAAAGAATGAAGCTGCGCGGATGGCAGCTCTGGTGGAAGC
AGAGAAGGAGTGTAACCTGGAGCTCTCAGAGAAACTGAAGGGAGTCACCAAAAACTGGGAAGATGTACCAGGAGACCAGGTCAAGCCCGA
CCAATACACTGAGGCCCTGGCCCAGAGGGACAAGAGAATTGAAGAACTGAATCAGAGCCTGGCTGCCCAGGAGAGGCTTGTAGAACAGCT
ATCTCGGGAGAAACAACAACTGCTACATCTGTTGGAGGAGCCAACTAGCATGGAAGTGCAGCCCATGACTGAAGAGTTGCTGAAACAACA
AAAGCTGAATTCACATGAGACCACTATAACTCAGCAGTCTGTATCTGATTCCCACTTGGCAGAACTCCAGGAAAAAATCCAGCAAACAGA
GGCCACCAACAAGATTCTTCAAGAGAAACTTAATGAAATGAGCTATGAACTAAAGTGTGCTCAGGAGTCGTCTCAAAAGCAAGATGGTAC
AATTCAGAACCTCAAGGAAACTCTGAAAAGCAGGGAACGTGAGACTGAGGAGTTGTACCAGGTAATTGAAGGTCAAAATGACACAATGGC
AAAGCTTCGAGAAATGCTGCACCAAAGCCAGCTTGGACAACTTCACAGCTCAGAGGGTACTTCTCCAGCTCAGCAACAGGTAGCTCTGCT
TGATCTTCAGAGTGCTTTATTCTGCAGCCAACTTGAAATACAGAAGCTCCAGAGGGTGGTACGACAGAAAGAGCGCCAACTGGCTGATGC
CAAACAATGTGTGCAATTTGTAGAGGCTGCAGCACACGAGAGTGAACAGCAGAAAGAGGCTTCTTGGAAACATAACCAGGAATTGCGAAA
AGCCTTGCAGCAGCTACAAGAAGAATTGCAGAATAAGAGCCAACAGCTTCGTGCCTGGGAGGCTGAAAAATACAATGAGATTCGAACCCA
GGAACAAAACATCCAGCACCTAAACCATAGTCTGAGTCACAAGGAGCAGTTGCTTCAGGAATTTCGGGAGCTCCTACAGTATCGAGATAA
CTCAGACAAAACCCTTGAAGCAAATGAAATGTTGCTTGAGAAACTTCGCCAGCGAATACATGATAAAGCTGTTGCTCTGGAGCGGGCTAT
AGATGAAAAATTCTCTGCTCTAGAAGAGAAAGAAAAAGAACTGCGCCAGCTTCGTCTTGCTGTGAGAGAGCGAGATCATGACTTAGAGAG
ACTGCGCGATGTCCTCTCCTCCAATGAAGCTACTATGCAAAGTATGGAGAGTCTCCTGAGGGCCAAAGGCCTGGAAGTGGAACAGTTATC
TACTACCTGTCAAAACCTCCAGTGGCTGAAAGAAGAAATGGAAACCAAATTTAGCCGTTGGCAGAAGGAACAAGAGAGTATCATTCAGCA
GTTACAGACGTCTCTTCATGATAGGAACAAAGAAGTGGAGGATCTTAGTGCAACACTGCTCTGCAAACTTGGACCAGGGCAGAGTGAGAT
AGCAGAGGAGCTGTGCCAGCGTCTACAGCGAAAGGAAAGGATGCTGCAGGACCTTCTAAGTGATCGAAATAAACAAGTGCTGGAACATGA
AATGGAGATTCAAGGCCTGCTTCAGTCTGTGAGCACCAGGGAGCAGGAAAGCCAAGCCACAGAGGATGTGGATTACACACAAGTCGTCTT
TTCTGACCCTGGAGAACTAAAAAATGACTCCCCGCTGGACTATGAGAACATAAAGGAAATCACAGATTATGTCAATGTCAATCCAGAAAG
ACACAAGCCCAGTTTCTGGTATTTTGTCAACCCTGCTCTGTCTGAGCCAGCGGAATATGATCAAGTGGCCATGTGAATTCCAAATATTTT
TAATGGGGTCCAGTTCTCTATGGATTCTTACATTTAATTTGTAGGGAAATGCCATTTTTCCCCCTTAAACAAGGCATGGGGCTCACAAGT
CTATGGAGACAGGCCAAAAAGAATGTGGAGAAGAAAACTGATAAATACACAGAGGTCCTCAAGACCCATGGACTCCTGGTCTGTACCCAA
AAAAGCTGTTCGTTCCTCAAAAACAAAAACAAGGCTTGGCTGGGAAAACAGGCCAATGCCCCGGCAAGAAAGGTTGAGATCAGATGTTAG
GAAGAACTTTCAGGTAAAGTATGAGAACTATGGAGTCCATCAGCAGAGATAGTAGTGAAGTCTCTCCCCAGGGAAAATTTTAAAAAGGTT
GAATCAGCTGTTGTAGAGTTCTATTTGGCAATCTCATGGTTAAATGACTTCCCTTTGAGCTCTTTAATTATTGGCAATAAACAACTTCTT

>63729_63729_3_PDE4DIP-C1orf186_PDE4DIP_chr1_144915445_ENST00000369349_C1orf186_chr1_206239579_ENST00000331555_length(amino acids)=754AA_BP=688
MASCCGAAAPCSWVEGAIGHAPPHGLPIMSNGYRTLSQHLNDLKKENFSLKLRIYFLEERMQQKYEASREDIYKRNIELKVEVESLKREL
QDKKQHLDKTWADVENLNSQNEAELRRQFEERQQETEHVYELLENKIQLLQEESRLAKNEAARMAALVEAEKECNLELSEKLKGVTKNWE
DVPGDQVKPDQYTEALAQRDKRIEELNQSLAAQERLVEQLSREKQQLLHLLEEPTSMEVQPMTEELLKQQKLNSHETTITQQSVSDSHLA
ELQEKIQQTEATNKILQEKLNEMSYELKCAQESSQKQDGTIQNLKETLKSRERETEELYQVIEGQNDTMAKLREMLHQSQLGQLHSSEGT
SPAQQQVALLDLQSALFCSQLEIQKLQRVVRQKERQLADAKQCVQFVEAAAHESEQQKEASWKHNQELRKALQQLQEELQNKSQQLRAWE
AEKYNEIRTQEQNIQHLNHSLSHKEQLLQEFRELLQYRDNSDKTLEANEMLLEKLRQRIHDKAVALERAIDEKFSALEEKEKELRQLRLA
VRERDHDLERLRDVLSSNEATMQSMESLLRAKGLEVEQLSTTCQNLQWLKEEMETKFSRWQKEQESIIQQLQTSLHDRNKEVEDLSATLL
CKLGPGQSEIAEELCQRLQRKERMLQDLLSDRNKQVLEHEMEIQGLLQSVSTREQESQATEDVDYTQVVFSDPGELKNDSPLDYENIKEI

--------------------------------------------------------------
>63729_63729_4_PDE4DIP-C1orf186_PDE4DIP_chr1_144915445_ENST00000369351_C1orf186_chr1_206239579_ENST00000331555_length(transcript)=2797nt_BP=2089nt
GCAGCCTCAGCAGCGTCCCAGCCGGCTGGCTTCATGCTGCGGTGCAGCTGCACCATGTTCCTGGGTTGAGGGGGCAATCGGGCACGCTCC
TCCCCATGGGTTGCCCATCATGTCTAATGGATATCGCACTCTGTCCCAGCACCTCAATGACCTGAAGAAGGAGAACTTCAGCCTCAAGCT
GCGCATCTACTTCCTGGAGGAGCGCATGCAACAGAAGTATGAGGCCAGCCGGGAGGACATCTACAAGCGGAACATTGAGCTGAAGGTTGA
AGTGGAGAGCTTGAAACGAGAACTCCAGGACAAGAAACAGCATCTGGATAAAACATGGGCTGATGTGGAGAATCTCAACAGTCAGAATGA
AGCTGAGCTCCGACGCCAGTTTGAGGAGCGACAGCAGGAGACGGAGCATGTTTATGAGCTCTTGGAGAATAAGATCCAGCTTCTGCAGGA
GGAATCCAGGCTAGCAAAGAATGAAGCTGCGCGGATGGCAGCTCTGGTGGAAGCAGAGAAGGAGTGTAACCTGGAGCTCTCAGAGAAACT
GAAGGGAGTCACCAAAAACTGGGAAGATGTACCAGGAGACCAGGTCAAGCCCGACCAATACACTGAGGCCCTGGCCCAGAGGGACAAGAG
AATTGAAGAACTGAATCAGAGCCTGGCTGCCCAGGAGAGGCTTGTAGAACAGCTATCTCGGGAGAAACAACAACTGCTACATCTGTTGGA
GGAGCCAACTAGCATGGAAGTGCAGCCCATGACTGAAGAGTTGCTGAAACAACAAAAGCTGAATTCACATGAGACCACTATAACTCAGCA
GTCTGTATCTGATTCCCACTTGGCAGAACTCCAGGAAAAAATCCAGCAAACAGAGGCCACCAACAAGATTCTTCAAGAGAAACTTAATGA
AATGAGCTATGAACTAAAGTGTGCTCAGGAGTCGTCTCAAAAGCAAGATGGTACAATTCAGAACCTCAAGGAAACTCTGAAAAGCAGGGA
ACGTGAGACTGAGGAGTTGTACCAGGTAATTGAAGGTCAAAATGACACAATGGCAAAGCTTCGAGAAATGCTGCACCAAAGCCAGCTTGG
ACAACTTCACAGCTCAGAGGGTACTTCTCCAGCTCAGCAACAGGTAGCTCTGCTTGATCTTCAGAGTGCTTTATTCTGCAGCCAACTTGA
AATACAGAAGCTCCAGAGGGTGGTACGACAGAAAGAGCGCCAACTGGCTGATGCCAAACAATGTGTGCAATTTGTAGAGGCTGCAGCACA
CGAGAGTGAACAGCAGAAAGAGGCTTCTTGGAAACATAACCAGGAATTGCGAAAAGCCTTGCAGCAGCTACAAGAAGAATTGCAGAATAA
GAGCCAACAGCTTCGTGCCTGGGAGGCTGAAAAATACAATGAGATTCGAACCCAGGAACAAAACATCCAGCACCTAAACCATAGTCTGAG
TCACAAGGAGCAGTTGCTTCAGGAATTTCGGGAGCTCCTACAGTATCGAGATAACTCAGACAAAACCCTTGAAGCAAATGAAATGTTGCT
TGAGAAACTTCGCCAGCGAATACATGATAAAGCTGTTGCTCTGGAGCGGGCTATAGATGAAAAATTCTCTGCTCTAGAAGAGAAAGAAAA
AGAACTGCGCCAGCTTCGTCTTGCTGTGAGAGAGCGAGATCATGACTTAGAGAGACTGCGCGATGTCCTCTCCTCCAATGAAGCTACTAT
GCAAAGTATGGAGAGTCTCCTGAGGGCCAAAGGCCTGGAAGTGGAACAGTTATCTACTACCTGTCAAAACCTCCAGTGGCTGAAAGAAGA
AATGGAAACCAAATTTAGCCGTTGGCAGAAGGAACAAGAGAGTATCATTCAGCAGTTACAGACGTCTCTTCATGATAGGAACAAAGAAGT
GGAGGATCTTAGTGCAACACTGCTCTGCAAACTTGGACCAGGGCAGAGTGAGATAGCAGAGGAGCTGTGCCAGCGTCTACAGCGAAAGGA
AAGGATGCTGCAGGACCTTCTAAGTGATCGAAATAAACAAGTGCTGGAACATGAAATGGAGATTCAAGGCCTGCTTCAGTCTGTGAGCAC
CAGGGAGCAGGAAAGCCAAGCCACAGAGGATGTGGATTACACACAAGTCGTCTTTTCTGACCCTGGAGAACTAAAAAATGACTCCCCGCT
GGACTATGAGAACATAAAGGAAATCACAGATTATGTCAATGTCAATCCAGAAAGACACAAGCCCAGTTTCTGGTATTTTGTCAACCCTGC
TCTGTCTGAGCCAGCGGAATATGATCAAGTGGCCATGTGAATTCCAAATATTTTTAATGGGGTCCAGTTCTCTATGGATTCTTACATTTA
ATTTGTAGGGAAATGCCATTTTTCCCCCTTAAACAAGGCATGGGGCTCACAAGTCTATGGAGACAGGCCAAAAAGAATGTGGAGAAGAAA
ACTGATAAATACACAGAGGTCCTCAAGACCCATGGACTCCTGGTCTGTACCCAAAAAAGCTGTTCGTTCCTCAAAAACAAAAACAAGGCT
TGGCTGGGAAAACAGGCCAATGCCCCGGCAAGAAAGGTTGAGATCAGATGTTAGGAAGAACTTTCAGGTAAAGTATGAGAACTATGGAGT
CCATCAGCAGAGATAGTAGTGAAGTCTCTCCCCAGGGAAAATTTTAAAAAGGTTGAATCAGCTGTTGTAGAGTTCTATTTGGCAATCTCA
TGGTTAAATGACTTCCCTTTGAGCTCTTTAATTATTGGCAATAAACAACTTCTTTAAAAGTTTTAAATAAAATAGCAACCACCACCAGTT

>63729_63729_4_PDE4DIP-C1orf186_PDE4DIP_chr1_144915445_ENST00000369351_C1orf186_chr1_206239579_ENST00000331555_length(amino acids)=754AA_BP=688
MASCCGAAAPCSWVEGAIGHAPPHGLPIMSNGYRTLSQHLNDLKKENFSLKLRIYFLEERMQQKYEASREDIYKRNIELKVEVESLKREL
QDKKQHLDKTWADVENLNSQNEAELRRQFEERQQETEHVYELLENKIQLLQEESRLAKNEAARMAALVEAEKECNLELSEKLKGVTKNWE
DVPGDQVKPDQYTEALAQRDKRIEELNQSLAAQERLVEQLSREKQQLLHLLEEPTSMEVQPMTEELLKQQKLNSHETTITQQSVSDSHLA
ELQEKIQQTEATNKILQEKLNEMSYELKCAQESSQKQDGTIQNLKETLKSRERETEELYQVIEGQNDTMAKLREMLHQSQLGQLHSSEGT
SPAQQQVALLDLQSALFCSQLEIQKLQRVVRQKERQLADAKQCVQFVEAAAHESEQQKEASWKHNQELRKALQQLQEELQNKSQQLRAWE
AEKYNEIRTQEQNIQHLNHSLSHKEQLLQEFRELLQYRDNSDKTLEANEMLLEKLRQRIHDKAVALERAIDEKFSALEEKEKELRQLRLA
VRERDHDLERLRDVLSSNEATMQSMESLLRAKGLEVEQLSTTCQNLQWLKEEMETKFSRWQKEQESIIQQLQTSLHDRNKEVEDLSATLL
CKLGPGQSEIAEELCQRLQRKERMLQDLLSDRNKQVLEHEMEIQGLLQSVSTREQESQATEDVDYTQVVFSDPGELKNDSPLDYENIKEI

--------------------------------------------------------------
>63729_63729_5_PDE4DIP-C1orf186_PDE4DIP_chr1_144915445_ENST00000369354_C1orf186_chr1_206239579_ENST00000331555_length(transcript)=2878nt_BP=2170nt
AGAGCAGTGAGCCCAGTCCCGAGTCCCGGAGAGAGCTCCAGCAATAGGGGCCATGTCGCCGTAGCCCCAGCCTCTCGGTCCGCAGCCTCA
GCAGCGTCCCAGCCGGCTGGCTTCATGCTGCGGTGCAGCTGCACCATGTTCCTGGGTTGAGGGGGCAATCGGGCACGCTCCTCCCCATGG
GTTGCCCATCATGTCTAATGGATATCGCACTCTGTCCCAGCACCTCAATGACCTGAAGAAGGAGAACTTCAGCCTCAAGCTGCGCATCTA
CTTCCTGGAGGAGCGCATGCAACAGAAGTATGAGGCCAGCCGGGAGGACATCTACAAGCGGAACATTGAGCTGAAGGTTGAAGTGGAGAG
CTTGAAACGAGAACTCCAGGACAAGAAACAGCATCTGGATAAAACATGGGCTGATGTGGAGAATCTCAACAGTCAGAATGAAGCTGAGCT
CCGACGCCAGTTTGAGGAGCGACAGCAGGAGACGGAGCATGTTTATGAGCTCTTGGAGAATAAGATCCAGCTTCTGCAGGAGGAATCCAG
GCTAGCAAAGAATGAAGCTGCGCGGATGGCAGCTCTGGTGGAAGCAGAGAAGGAGTGTAACCTGGAGCTCTCAGAGAAACTGAAGGGAGT
CACCAAAAACTGGGAAGATGTACCAGGAGACCAGGTCAAGCCCGACCAATACACTGAGGCCCTGGCCCAGAGGGACAAGAGAATTGAAGA
ACTGAATCAGAGCCTGGCTGCCCAGGAGAGGCTTGTAGAACAGCTATCTCGGGAGAAACAACAACTGCTACATCTGTTGGAGGAGCCAAC
TAGCATGGAAGTGCAGCCCATGACTGAAGAGTTGCTGAAACAACAAAAGCTGAATTCACATGAGACCACTATAACTCAGCAGTCTGTATC
TGATTCCCACTTGGCAGAACTCCAGGAAAAAATCCAGCAAACAGAGGCCACCAACAAGATTCTTCAAGAGAAACTTAATGAAATGAGCTA
TGAACTAAAGTGTGCTCAGGAGTCGTCTCAAAAGCAAGATGGTACAATTCAGAACCTCAAGGAAACTCTGAAAAGCAGGGAACGTGAGAC
TGAGGAGTTGTACCAGGTAATTGAAGGTCAAAATGACACAATGGCAAAGCTTCGAGAAATGCTGCACCAAAGCCAGCTTGGACAACTTCA
CAGCTCAGAGGGTACTTCTCCAGCTCAGCAACAGGTAGCTCTGCTTGATCTTCAGAGTGCTTTATTCTGCAGCCAACTTGAAATACAGAA
GCTCCAGAGGGTGGTACGACAGAAAGAGCGCCAACTGGCTGATGCCAAACAATGTGTGCAATTTGTAGAGGCTGCAGCACACGAGAGTGA
ACAGCAGAAAGAGGCTTCTTGGAAACATAACCAGGAATTGCGAAAAGCCTTGCAGCAGCTACAAGAAGAATTGCAGAATAAGAGCCAACA
GCTTCGTGCCTGGGAGGCTGAAAAATACAATGAGATTCGAACCCAGGAACAAAACATCCAGCACCTAAACCATAGTCTGAGTCACAAGGA
GCAGTTGCTTCAGGAATTTCGGGAGCTCCTACAGTATCGAGATAACTCAGACAAAACCCTTGAAGCAAATGAAATGTTGCTTGAGAAACT
TCGCCAGCGAATACATGATAAAGCTGTTGCTCTGGAGCGGGCTATAGATGAAAAATTCTCTGCTCTAGAAGAGAAAGAAAAAGAACTGCG
CCAGCTTCGTCTTGCTGTGAGAGAGCGAGATCATGACTTAGAGAGACTGCGCGATGTCCTCTCCTCCAATGAAGCTACTATGCAAAGTAT
GGAGAGTCTCCTGAGGGCCAAAGGCCTGGAAGTGGAACAGTTATCTACTACCTGTCAAAACCTCCAGTGGCTGAAAGAAGAAATGGAAAC
CAAATTTAGCCGTTGGCAGAAGGAACAAGAGAGTATCATTCAGCAGTTACAGACGTCTCTTCATGATAGGAACAAAGAAGTGGAGGATCT
TAGTGCAACACTGCTCTGCAAACTTGGACCAGGGCAGAGTGAGATAGCAGAGGAGCTGTGCCAGCGTCTACAGCGAAAGGAAAGGATGCT
GCAGGACCTTCTAAGTGATCGAAATAAACAAGTGCTGGAACATGAAATGGAGATTCAAGGCCTGCTTCAGTCTGTGAGCACCAGGGAGCA
GGAAAGCCAAGCCACAGAGGATGTGGATTACACACAAGTCGTCTTTTCTGACCCTGGAGAACTAAAAAATGACTCCCCGCTGGACTATGA
GAACATAAAGGAAATCACAGATTATGTCAATGTCAATCCAGAAAGACACAAGCCCAGTTTCTGGTATTTTGTCAACCCTGCTCTGTCTGA
GCCAGCGGAATATGATCAAGTGGCCATGTGAATTCCAAATATTTTTAATGGGGTCCAGTTCTCTATGGATTCTTACATTTAATTTGTAGG
GAAATGCCATTTTTCCCCCTTAAACAAGGCATGGGGCTCACAAGTCTATGGAGACAGGCCAAAAAGAATGTGGAGAAGAAAACTGATAAA
TACACAGAGGTCCTCAAGACCCATGGACTCCTGGTCTGTACCCAAAAAAGCTGTTCGTTCCTCAAAAACAAAAACAAGGCTTGGCTGGGA
AAACAGGCCAATGCCCCGGCAAGAAAGGTTGAGATCAGATGTTAGGAAGAACTTTCAGGTAAAGTATGAGAACTATGGAGTCCATCAGCA
GAGATAGTAGTGAAGTCTCTCCCCAGGGAAAATTTTAAAAAGGTTGAATCAGCTGTTGTAGAGTTCTATTTGGCAATCTCATGGTTAAAT

>63729_63729_5_PDE4DIP-C1orf186_PDE4DIP_chr1_144915445_ENST00000369354_C1orf186_chr1_206239579_ENST00000331555_length(amino acids)=754AA_BP=688
MASCCGAAAPCSWVEGAIGHAPPHGLPIMSNGYRTLSQHLNDLKKENFSLKLRIYFLEERMQQKYEASREDIYKRNIELKVEVESLKREL
QDKKQHLDKTWADVENLNSQNEAELRRQFEERQQETEHVYELLENKIQLLQEESRLAKNEAARMAALVEAEKECNLELSEKLKGVTKNWE
DVPGDQVKPDQYTEALAQRDKRIEELNQSLAAQERLVEQLSREKQQLLHLLEEPTSMEVQPMTEELLKQQKLNSHETTITQQSVSDSHLA
ELQEKIQQTEATNKILQEKLNEMSYELKCAQESSQKQDGTIQNLKETLKSRERETEELYQVIEGQNDTMAKLREMLHQSQLGQLHSSEGT
SPAQQQVALLDLQSALFCSQLEIQKLQRVVRQKERQLADAKQCVQFVEAAAHESEQQKEASWKHNQELRKALQQLQEELQNKSQQLRAWE
AEKYNEIRTQEQNIQHLNHSLSHKEQLLQEFRELLQYRDNSDKTLEANEMLLEKLRQRIHDKAVALERAIDEKFSALEEKEKELRQLRLA
VRERDHDLERLRDVLSSNEATMQSMESLLRAKGLEVEQLSTTCQNLQWLKEEMETKFSRWQKEQESIIQQLQTSLHDRNKEVEDLSATLL
CKLGPGQSEIAEELCQRLQRKERMLQDLLSDRNKQVLEHEMEIQGLLQSVSTREQESQATEDVDYTQVVFSDPGELKNDSPLDYENIKEI

--------------------------------------------------------------
>63729_63729_6_PDE4DIP-C1orf186_PDE4DIP_chr1_144915445_ENST00000369356_C1orf186_chr1_206239579_ENST00000331555_length(transcript)=2979nt_BP=2271nt
ACACCACTTGTGTCTGAGTTCACGCAGCATGTTCCTCTGTCAGGGATTCCGCAAATATCTCCCTGAGGTAAAAAAGGAAAGTGTGCTGCG
CTCCAGCACCCAGAGCAGTGAGCCCAGTCCCGAGTCCCGGAGAGAGCTCCAGCAATAGGGGCCATGTCGCCGTAGCCCCAGCCTCTCGGT
CCGCAGCCTCAGCAGCGTCCCAGCCGGCTGGCTTCATGCTGCGGTGCAGCTGCACCATGTTCCTGGGTTGAGGGGGCAATCGGGCACGCT
CCTCCCCATGGGTTGCCCATCATGTCTAATGGATATCGCACTCTGTCCCAGCACCTCAATGACCTGAAGAAGGAGAACTTCAGCCTCAAG
CTGCGCATCTACTTCCTGGAGGAGCGCATGCAACAGAAGTATGAGGCCAGCCGGGAGGACATCTACAAGCGGAACATTGAGCTGAAGGTT
GAAGTGGAGAGCTTGAAACGAGAACTCCAGGACAAGAAACAGCATCTGGATAAAACATGGGCTGATGTGGAGAATCTCAACAGTCAGAAT
GAAGCTGAGCTCCGACGCCAGTTTGAGGAGCGACAGCAGGAGACGGAGCATGTTTATGAGCTCTTGGAGAATAAGATCCAGCTTCTGCAG
GAGGAATCCAGGCTAGCAAAGAATGAAGCTGCGCGGATGGCAGCTCTGGTGGAAGCAGAGAAGGAGTGTAACCTGGAGCTCTCAGAGAAA
CTGAAGGGAGTCACCAAAAACTGGGAAGATGTACCAGGAGACCAGGTCAAGCCCGACCAATACACTGAGGCCCTGGCCCAGAGGGACAAG
AGAATTGAAGAACTGAATCAGAGCCTGGCTGCCCAGGAGAGGCTTGTAGAACAGCTATCTCGGGAGAAACAACAACTGCTACATCTGTTG
GAGGAGCCAACTAGCATGGAAGTGCAGCCCATGACTGAAGAGTTGCTGAAACAACAAAAGCTGAATTCACATGAGACCACTATAACTCAG
CAGTCTGTATCTGATTCCCACTTGGCAGAACTCCAGGAAAAAATCCAGCAAACAGAGGCCACCAACAAGATTCTTCAAGAGAAACTTAAT
GAAATGAGCTATGAACTAAAGTGTGCTCAGGAGTCGTCTCAAAAGCAAGATGGTACAATTCAGAACCTCAAGGAAACTCTGAAAAGCAGG
GAACGTGAGACTGAGGAGTTGTACCAGGTAATTGAAGGTCAAAATGACACAATGGCAAAGCTTCGAGAAATGCTGCACCAAAGCCAGCTT
GGACAACTTCACAGCTCAGAGGGTACTTCTCCAGCTCAGCAACAGGTAGCTCTGCTTGATCTTCAGAGTGCTTTATTCTGCAGCCAACTT
GAAATACAGAAGCTCCAGAGGGTGGTACGACAGAAAGAGCGCCAACTGGCTGATGCCAAACAATGTGTGCAATTTGTAGAGGCTGCAGCA
CACGAGAGTGAACAGCAGAAAGAGGCTTCTTGGAAACATAACCAGGAATTGCGAAAAGCCTTGCAGCAGCTACAAGAAGAATTGCAGAAT
AAGAGCCAACAGCTTCGTGCCTGGGAGGCTGAAAAATACAATGAGATTCGAACCCAGGAACAAAACATCCAGCACCTAAACCATAGTCTG
AGTCACAAGGAGCAGTTGCTTCAGGAATTTCGGGAGCTCCTACAGTATCGAGATAACTCAGACAAAACCCTTGAAGCAAATGAAATGTTG
CTTGAGAAACTTCGCCAGCGAATACATGATAAAGCTGTTGCTCTGGAGCGGGCTATAGATGAAAAATTCTCTGCTCTAGAAGAGAAAGAA
AAAGAACTGCGCCAGCTTCGTCTTGCTGTGAGAGAGCGAGATCATGACTTAGAGAGACTGCGCGATGTCCTCTCCTCCAATGAAGCTACT
ATGCAAAGTATGGAGAGTCTCCTGAGGGCCAAAGGCCTGGAAGTGGAACAGTTATCTACTACCTGTCAAAACCTCCAGTGGCTGAAAGAA
GAAATGGAAACCAAATTTAGCCGTTGGCAGAAGGAACAAGAGAGTATCATTCAGCAGTTACAGACGTCTCTTCATGATAGGAACAAAGAA
GTGGAGGATCTTAGTGCAACACTGCTCTGCAAACTTGGACCAGGGCAGAGTGAGATAGCAGAGGAGCTGTGCCAGCGTCTACAGCGAAAG
GAAAGGATGCTGCAGGACCTTCTAAGTGATCGAAATAAACAAGTGCTGGAACATGAAATGGAGATTCAAGGCCTGCTTCAGTCTGTGAGC
ACCAGGGAGCAGGAAAGCCAAGCCACAGAGGATGTGGATTACACACAAGTCGTCTTTTCTGACCCTGGAGAACTAAAAAATGACTCCCCG
CTGGACTATGAGAACATAAAGGAAATCACAGATTATGTCAATGTCAATCCAGAAAGACACAAGCCCAGTTTCTGGTATTTTGTCAACCCT
GCTCTGTCTGAGCCAGCGGAATATGATCAAGTGGCCATGTGAATTCCAAATATTTTTAATGGGGTCCAGTTCTCTATGGATTCTTACATT
TAATTTGTAGGGAAATGCCATTTTTCCCCCTTAAACAAGGCATGGGGCTCACAAGTCTATGGAGACAGGCCAAAAAGAATGTGGAGAAGA
AAACTGATAAATACACAGAGGTCCTCAAGACCCATGGACTCCTGGTCTGTACCCAAAAAAGCTGTTCGTTCCTCAAAAACAAAAACAAGG
CTTGGCTGGGAAAACAGGCCAATGCCCCGGCAAGAAAGGTTGAGATCAGATGTTAGGAAGAACTTTCAGGTAAAGTATGAGAACTATGGA
GTCCATCAGCAGAGATAGTAGTGAAGTCTCTCCCCAGGGAAAATTTTAAAAAGGTTGAATCAGCTGTTGTAGAGTTCTATTTGGCAATCT
CATGGTTAAATGACTTCCCTTTGAGCTCTTTAATTATTGGCAATAAACAACTTCTTTAAAAGTTTTAAATAAAATAGCAACCACCACCAG

>63729_63729_6_PDE4DIP-C1orf186_PDE4DIP_chr1_144915445_ENST00000369356_C1orf186_chr1_206239579_ENST00000331555_length(amino acids)=754AA_BP=688
MASCCGAAAPCSWVEGAIGHAPPHGLPIMSNGYRTLSQHLNDLKKENFSLKLRIYFLEERMQQKYEASREDIYKRNIELKVEVESLKREL
QDKKQHLDKTWADVENLNSQNEAELRRQFEERQQETEHVYELLENKIQLLQEESRLAKNEAARMAALVEAEKECNLELSEKLKGVTKNWE
DVPGDQVKPDQYTEALAQRDKRIEELNQSLAAQERLVEQLSREKQQLLHLLEEPTSMEVQPMTEELLKQQKLNSHETTITQQSVSDSHLA
ELQEKIQQTEATNKILQEKLNEMSYELKCAQESSQKQDGTIQNLKETLKSRERETEELYQVIEGQNDTMAKLREMLHQSQLGQLHSSEGT
SPAQQQVALLDLQSALFCSQLEIQKLQRVVRQKERQLADAKQCVQFVEAAAHESEQQKEASWKHNQELRKALQQLQEELQNKSQQLRAWE
AEKYNEIRTQEQNIQHLNHSLSHKEQLLQEFRELLQYRDNSDKTLEANEMLLEKLRQRIHDKAVALERAIDEKFSALEEKEKELRQLRLA
VRERDHDLERLRDVLSSNEATMQSMESLLRAKGLEVEQLSTTCQNLQWLKEEMETKFSRWQKEQESIIQQLQTSLHDRNKEVEDLSATLL
CKLGPGQSEIAEELCQRLQRKERMLQDLLSDRNKQVLEHEMEIQGLLQSVSTREQESQATEDVDYTQVVFSDPGELKNDSPLDYENIKEI

--------------------------------------------------------------
>63729_63729_7_PDE4DIP-C1orf186_PDE4DIP_chr1_144915445_ENST00000369359_C1orf186_chr1_206239579_ENST00000331555_length(transcript)=3138nt_BP=2430nt
ACCGTAGCTAGGACTGGGGTGGCCAGGCCCAGGAAATCCATGAAGGGCACAGACAGCGGGTCCTGCTGCCGCCGCCGATGCGACTTTGGC
TGCTGCTGTCGCGCGTCCCGCCGGGCTCACTACACGCCTTACCGGTCCGGGGACGCGACGCGAACCCCTCAGTCCCCACGGCAGACCCCG
AGCCGGGAAAGACGGCGCCCGGAGCCAGCCGGGAGCTGGGCAGCAGCGGCCGAGGAGGAAGAAGCAGCTGCGGCGGCCACACCCTGGATG
AGAGATTATTTTGCAGAGGATGATGGGGAGATGGTACCCAGAACGAGTCACACAGCAGCTTTTCTTAGTGACACTAAAGATCGAGGCCCT
CCAGTGCAGTCACAGATCTGGAGAAGTGGTGAAAAGGTCCCGTTTGTGCAGACATATTCCTTGAGAGCATTTGAGAAACCCCCTCAGGTA
CAGACCCAGGCTCTTCGAGACTTTGAGAAGCACCTCAATGACCTGAAGAAGGAGAACTTCAGCCTCAAGCTGCGCATCTACTTCCTGGAG
GAGCGCATGCAACAGAAGTATGAGGCCAGCCGGGAGGACATCTACAAGCGGAACATTGAGCTGAAGGTTGAAGTGGAGAGCTTGAAACGA
GAACTCCAGGACAAGAAACAGCATCTGGATAAAACATGGGCTGATGTGGAGAATCTCAACAGTCAGAATGAAGCTGAGCTCCGACGCCAG
TTTGAGGAGCGACAGCAGGAGACGGAGCATGTTTATGAGCTCTTGGAGAATAAGATCCAGCTTCTGCAGGAGGAATCCAGGCTAGCAAAG
AATGAAGCTGCGCGGATGGCAGCTCTGGTGGAAGCAGAGAAGGAGTGTAACCTGGAGCTCTCAGAGAAACTGAAGGGAGTCACCAAAAAC
TGGGAAGATGTACCAGGAGACCAGGTCAAGCCCGACCAATACACTGAGGCCCTGGCCCAGAGGGACAAGAGAATTGAAGAACTGAATCAG
AGCCTGGCTGCCCAGGAGAGGCTTGTAGAACAGCTATCTCGGGAGAAACAACAACTGCTACATCTGTTGGAGGAGCCAACTAGCATGGAA
GTGCAGCCCATGACTGAAGAGTTGCTGAAACAACAAAAGCTGAATTCACATGAGACCACTATAACTCAGCAGTCTGTATCTGATTCCCAC
TTGGCAGAACTCCAGGAAAAAATCCAGCAAACAGAGGCCACCAACAAGATTCTTCAAGAGAAACTTAATGAAATGAGCTATGAACTAAAG
TGTGCTCAGGAGTCGTCTCAAAAGCAAGATGGTACAATTCAGAACCTCAAGGAAACTCTGAAAAGCAGGGAACGTGAGACTGAGGAGTTG
TACCAGGTAATTGAAGGTCAAAATGACACAATGGCAAAGCTTCGAGAAATGCTGCACCAAAGCCAGCTTGGACAACTTCACAGCTCAGAG
GGTACTTCTCCAGCTCAGCAACAGGTAGCTCTGCTTGATCTTCAGAGTGCTTTATTCTGCAGCCAACTTGAAATACAGAAGCTCCAGAGG
GTGGTACGACAGAAAGAGCGCCAACTGGCTGATGCCAAACAATGTGTGCAATTTGTAGAGGCTGCAGCACACGAGAGTGAACAGCAGAAA
GAGGCTTCTTGGAAACATAACCAGGAATTGCGAAAAGCCTTGCAGCAGCTACAAGAAGAATTGCAGAATAAGAGCCAACAGCTTCGTGCC
TGGGAGGCTGAAAAATACAATGAGATTCGAACCCAGGAACAAAACATCCAGCACCTAAACCATAGTCTGAGTCACAAGGAGCAGTTGCTT
CAGGAATTTCGGGAGCTCCTACAGTATCGAGATAACTCAGACAAAACCCTTGAAGCAAATGAAATGTTGCTTGAGAAACTTCGCCAGCGA
ATACATGATAAAGCTGTTGCTCTGGAGCGGGCTATAGATGAAAAATTCTCTGCTCTAGAAGAGAAAGAAAAAGAACTGCGCCAGCTTCGT
CTTGCTGTGAGAGAGCGAGATCATGACTTAGAGAGACTGCGCGATGTCCTCTCCTCCAATGAAGCTACTATGCAAAGTATGGAGAGTCTC
CTGAGGGCCAAAGGCCTGGAAGTGGAACAGTTATCTACTACCTGTCAAAACCTCCAGTGGCTGAAAGAAGAAATGGAAACCAAATTTAGC
CGTTGGCAGAAGGAACAAGAGAGTATCATTCAGCAGTTACAGACGTCTCTTCATGATAGGAACAAAGAAGTGGAGGATCTTAGTGCAACA
CTGCTCTGCAAACTTGGACCAGGGCAGAGTGAGATAGCAGAGGAGCTGTGCCAGCGTCTACAGCGAAAGGAAAGGATGCTGCAGGACCTT
CTAAGTGATCGAAATAAACAAGTGCTGGAACATGAAATGGAGATTCAAGGCCTGCTTCAGTCTGTGAGCACCAGGGAGCAGGAAAGCCAA
GCCACAGAGGATGTGGATTACACACAAGTCGTCTTTTCTGACCCTGGAGAACTAAAAAATGACTCCCCGCTGGACTATGAGAACATAAAG
GAAATCACAGATTATGTCAATGTCAATCCAGAAAGACACAAGCCCAGTTTCTGGTATTTTGTCAACCCTGCTCTGTCTGAGCCAGCGGAA
TATGATCAAGTGGCCATGTGAATTCCAAATATTTTTAATGGGGTCCAGTTCTCTATGGATTCTTACATTTAATTTGTAGGGAAATGCCAT
TTTTCCCCCTTAAACAAGGCATGGGGCTCACAAGTCTATGGAGACAGGCCAAAAAGAATGTGGAGAAGAAAACTGATAAATACACAGAGG
TCCTCAAGACCCATGGACTCCTGGTCTGTACCCAAAAAAGCTGTTCGTTCCTCAAAAACAAAAACAAGGCTTGGCTGGGAAAACAGGCCA
ATGCCCCGGCAAGAAAGGTTGAGATCAGATGTTAGGAAGAACTTTCAGGTAAAGTATGAGAACTATGGAGTCCATCAGCAGAGATAGTAG
TGAAGTCTCTCCCCAGGGAAAATTTTAAAAAGGTTGAATCAGCTGTTGTAGAGTTCTATTTGGCAATCTCATGGTTAAATGACTTCCCTT

>63729_63729_7_PDE4DIP-C1orf186_PDE4DIP_chr1_144915445_ENST00000369359_C1orf186_chr1_206239579_ENST00000331555_length(amino acids)=863AA_BP=797
MKGTDSGSCCRRRCDFGCCCRASRRAHYTPYRSGDATRTPQSPRQTPSRERRRPEPAGSWAAAAEEEEAAAAATPWMRDYFAEDDGEMVP
RTSHTAAFLSDTKDRGPPVQSQIWRSGEKVPFVQTYSLRAFEKPPQVQTQALRDFEKHLNDLKKENFSLKLRIYFLEERMQQKYEASRED
IYKRNIELKVEVESLKRELQDKKQHLDKTWADVENLNSQNEAELRRQFEERQQETEHVYELLENKIQLLQEESRLAKNEAARMAALVEAE
KECNLELSEKLKGVTKNWEDVPGDQVKPDQYTEALAQRDKRIEELNQSLAAQERLVEQLSREKQQLLHLLEEPTSMEVQPMTEELLKQQK
LNSHETTITQQSVSDSHLAELQEKIQQTEATNKILQEKLNEMSYELKCAQESSQKQDGTIQNLKETLKSRERETEELYQVIEGQNDTMAK
LREMLHQSQLGQLHSSEGTSPAQQQVALLDLQSALFCSQLEIQKLQRVVRQKERQLADAKQCVQFVEAAAHESEQQKEASWKHNQELRKA
LQQLQEELQNKSQQLRAWEAEKYNEIRTQEQNIQHLNHSLSHKEQLLQEFRELLQYRDNSDKTLEANEMLLEKLRQRIHDKAVALERAID
EKFSALEEKEKELRQLRLAVRERDHDLERLRDVLSSNEATMQSMESLLRAKGLEVEQLSTTCQNLQWLKEEMETKFSRWQKEQESIIQQL
QTSLHDRNKEVEDLSATLLCKLGPGQSEIAEELCQRLQRKERMLQDLLSDRNKQVLEHEMEIQGLLQSVSTREQESQATEDVDYTQVVFS

--------------------------------------------------------------
>63729_63729_8_PDE4DIP-C1orf186_PDE4DIP_chr1_144915445_ENST00000529945_C1orf186_chr1_206239579_ENST00000331555_length(transcript)=3617nt_BP=2909nt
AGACGCGAAGCCGCTGGCGCCATCTTGAAATCTGATCCTCCATCCCCGAGGCTTTGCGTCTGCGCGGCCGGCCGCTGCTGCTCCGGGAGC
CCAGTCTGCTAAAAGGGGAGGACGTTGAGGACGCGGCGGCTGGCGGGAGAGACAGCTGGGGAGAGACATGGCAGGGTCGGAGCGCGGCCT
GCGCCTCTGTCACTCAGCATCCTCTTAGGCGTTTCCACGCCCGCCCCCTGCCCGAGGGGCGGGGCTGACGGCTCTGGTACCCGGAGTCGG
CGCGCGGGGCAGGGGCGCGCCCCTGCAGAGTGGGGACCCCACTGGGCTGTGCCATGCTGACCGGAGACCACCGAGGCGGGAGACAGAGCG
CGGCGAAGAGCCATTGAGTGGTCACCCAGTAGCCGCCGCCGCCGCCGCCTCGGGAAGCTTGCCACCCGCTAGGAGGGAAGATGAAGGAGA
TTTGCAGGATCTGTGCCCGAGAGCTGTGTGGAAACCAGCGGCGCTGGATCTTCCACACGGCGTCCAAGCTCAATCTCCAGGTTCTGCTTT
CGCACGTCTTGGGCAAGGATGTCCCCCGCGATGGCAAAGCCGAGTTCGCTTGCAGCAAGTGTGCTTTCATGCTTGATCGAATCTATCGAT
TCGACACAGTTATTGCCCGGATTGAAGCGCTTTCTATTGAGCGCTTGCAAAAGCTGCTACTGGAGAAGGATCGCCTCAAGTTCTGCATTG
CCAGTATGTATCGGAAGAATAACGATGACTCTGGCGCGGAGATCAAGGCGGGGAATGGGACGGTTGACATGTCCGTCTTACCCGATGCGA
GATACTCTGCACTGCTCCAGGAGGACTTCGCCTATTCAGGGTTTGAGTGCTGGGTGGAGAATGAGGATCAGATCCAGGAGCCACACAGCT
GCCATGGTTCAGAAGGCCCTGGAAACCGACCCAGGAGATGCCGTGGTTGTGCCGCTTTGCGGGTTGCTGATTCTGACTATGAAGCCATTT
GTAAGGTACCTCGAAAGGTGGCCAGAAGTATCTCCTGCGGCCCTTCTAGCAGGTGGTCGACCAGCATTTGCACTGAAGAACCAGCGTTGT
CTGAGGTTGGGCCACCCGACTTAGCAAGCACAAAGGTACCCCCAGATGGAGAAAGCATGGAGGAAGAGACGCCTGGTTCCTCTGTGGAAT
CTTTGGATGCAAGCGTCCAGGCTAGCCCTCCACAACAGAAAGATGAGGAGACTGAGAGAAGTGCAAAGGAACTTGGAAAGTGTGACTGTT
GTTCAGATGATCAGGCTCCGCAGCATGGGTGTAATCACAAGCTGGAATTAGCTCTTAGCATGATTAAAGGTCTTGATTATAAGCCCATCC
AGAGCCCCCGAGGGAGCAGGCTTCCGATTCCAGTGAAATCCAGCCTACCTGGAGCCAAGCCTGGCCCTAGCATGACAGATGGAGTTAGTT
CCGGTTTCCTTAACAGGTCTTTGAAACCCCTTTACAAGACACCTGTGAGTTATCCCTTGGAGCTTTCAGACCTGCAGGAGCTGTGGGATG
ATCTCTGTGAAGATTATTTGCCGCTCCGGGTCCAGCCCATGACTGAAGAGTTGCTGAAACAACAAAAGCTGAATTCACATGAGACCACTA
TAACTCAGCAGTCTGTATCTGATTCCCACTTGGCAGAACTCCAGGAAAAAATCCAGCAAACAGAGGCCACCAACAAGATTCTTCAAGAGA
AACTTAATGAAATGAGCTATGAACTAAAGTGTGCTCAGGAGTCGTCTCAAAAGCAAGATGGTACAATTCAGAACCTCAAGGAAACTCTGA
AAAGCAGGGAACGTGAGACTGAGGAGTTGTACCAGGTAATTGAAGGTCAAAATGACACAATGGCAAAGCTTCGAGAAATGCTGCACCAAA
GCCAGCTTGGACAACTTCACAGCTCAGAGGGTACTTCTCCAGCTCAGCAACAGGTAGCTCTGCTTGATCTTCAGAGTGCTTTATTCTGCA
GCCAACTTGAAATACAGAAGCTCCAGAGGGTGGTACGACAGAAAGAGCGCCAACTGGCTGATGCCAAACAATGTGTGCAATTTGTAGAGG
CTGCAGCACACGAGAGTGAACAGCAGAAAGAGGCTTCTTGGAAACATAACCAGGAATTGCGAAAAGCCTTGCAGCAGCTACAAGAAGAAT
TGCAGAATAAGAGCCAACAGCTTCGTGCCTGGGAGGCTGAAAAATACAATGAGATTCGAACCCAGGAACAAAACATCCAGCACCTAAACC
ATAGTCTGAGTCACAAGGAGCAGTTGCTTCAGGAATTTCGGGAGCTCCTACAGTATCGAGATAACTCAGACAAAACCCTTGAAGCAAATG
AAATGTTGCTTGAGAAACTTCGCCAGCGAATACATGATAAAGCTGTTGCTCTGGAGCGGGCTATAGATGAAAAATTCTCTGCTCTAGAAG
AGAAAGAAAAAGAACTGCGCCAGCTTCGTCTTGCTGTGAGAGAGCGAGATCATGACTTAGAGAGACTGCGCGATGTCCTCTCCTCCAATG
AAGCTACTATGCAAAGTATGGAGAGTCTCCTGAGGGCCAAAGGCCTGGAAGTGGAACAGTTATCTACTACCTGTCAAAACCTCCAGTGGC
TGAAAGAAGAAATGGAAACCAAATTTAGCCGTTGGCAGAAGGAACAAGAGAGTATCATTCAGCAGTTACAGACGTCTCTTCATGATAGGA
ACAAAGAAGTGGAGGATCTTAGTGCAACACTGCTCTGCAAACTTGGACCAGGGCAGAGTGAGATAGCAGAGGAGCTGTGCCAGCGTCTAC
AGCGAAAGGAAAGGATGCTGCAGGACCTTCTAAGTGATCGAAATAAACAAGTGCTGGAACATGAAATGGAGATTCAAGGCCTGCTTCAGT
CTGTGAGCACCAGGGAGCAGGAAAGCCAAGCCACAGAGGATGTGGATTACACACAAGTCGTCTTTTCTGACCCTGGAGAACTAAAAAATG
ACTCCCCGCTGGACTATGAGAACATAAAGGAAATCACAGATTATGTCAATGTCAATCCAGAAAGACACAAGCCCAGTTTCTGGTATTTTG
TCAACCCTGCTCTGTCTGAGCCAGCGGAATATGATCAAGTGGCCATGTGAATTCCAAATATTTTTAATGGGGTCCAGTTCTCTATGGATT
CTTACATTTAATTTGTAGGGAAATGCCATTTTTCCCCCTTAAACAAGGCATGGGGCTCACAAGTCTATGGAGACAGGCCAAAAAGAATGT
GGAGAAGAAAACTGATAAATACACAGAGGTCCTCAAGACCCATGGACTCCTGGTCTGTACCCAAAAAAGCTGTTCGTTCCTCAAAAACAA
AAACAAGGCTTGGCTGGGAAAACAGGCCAATGCCCCGGCAAGAAAGGTTGAGATCAGATGTTAGGAAGAACTTTCAGGTAAAGTATGAGA
ACTATGGAGTCCATCAGCAGAGATAGTAGTGAAGTCTCTCCCCAGGGAAAATTTTAAAAAGGTTGAATCAGCTGTTGTAGAGTTCTATTT
GGCAATCTCATGGTTAAATGACTTCCCTTTGAGCTCTTTAATTATTGGCAATAAACAACTTCTTTAAAAGTTTTAAATAAAATAGCAACC

>63729_63729_8_PDE4DIP-C1orf186_PDE4DIP_chr1_144915445_ENST00000529945_C1orf186_chr1_206239579_ENST00000331555_length(amino acids)=889AA_BP=823
MKEICRICARELCGNQRRWIFHTASKLNLQVLLSHVLGKDVPRDGKAEFACSKCAFMLDRIYRFDTVIARIEALSIERLQKLLLEKDRLK
FCIASMYRKNNDDSGAEIKAGNGTVDMSVLPDARYSALLQEDFAYSGFECWVENEDQIQEPHSCHGSEGPGNRPRRCRGCAALRVADSDY
EAICKVPRKVARSISCGPSSRWSTSICTEEPALSEVGPPDLASTKVPPDGESMEEETPGSSVESLDASVQASPPQQKDEETERSAKELGK
CDCCSDDQAPQHGCNHKLELALSMIKGLDYKPIQSPRGSRLPIPVKSSLPGAKPGPSMTDGVSSGFLNRSLKPLYKTPVSYPLELSDLQE
LWDDLCEDYLPLRVQPMTEELLKQQKLNSHETTITQQSVSDSHLAELQEKIQQTEATNKILQEKLNEMSYELKCAQESSQKQDGTIQNLK
ETLKSRERETEELYQVIEGQNDTMAKLREMLHQSQLGQLHSSEGTSPAQQQVALLDLQSALFCSQLEIQKLQRVVRQKERQLADAKQCVQ
FVEAAAHESEQQKEASWKHNQELRKALQQLQEELQNKSQQLRAWEAEKYNEIRTQEQNIQHLNHSLSHKEQLLQEFRELLQYRDNSDKTL
EANEMLLEKLRQRIHDKAVALERAIDEKFSALEEKEKELRQLRLAVRERDHDLERLRDVLSSNEATMQSMESLLRAKGLEVEQLSTTCQN
LQWLKEEMETKFSRWQKEQESIIQQLQTSLHDRNKEVEDLSATLLCKLGPGQSEIAEELCQRLQRKERMLQDLLSDRNKQVLEHEMEIQG

--------------------------------------------------------------
>63729_63729_9_PDE4DIP-C1orf186_PDE4DIP_chr1_144915445_ENST00000530740_C1orf186_chr1_206239579_ENST00000331555_length(transcript)=3138nt_BP=2430nt
ACCGTAGCTAGGACTGGGGTGGCCAGGCCCAGGAAATCCATGAAGGGCACAGACAGCGGGTCCTGCTGCCGCCGCCGATGCGACTTTGGC
TGCTGCTGTCGCGCGTCCCGCCGGGCTCACTACACGCCTTACCGGTCCGGGGACGCGACGCGAACCCCTCAGTCCCCACGGCAGACCCCG
AGCCGGGAAAGACGGCGCCCGGAGCCAGCCGGGAGCTGGGCAGCAGCGGCCGAGGAGGAAGAAGCAGCTGCGGCGGCCACACCCTGGATG
AGAGATTATTTTGCAGAGGATGATGGGGAGATGGTACCCAGAACGAGTCACACAGCAGCTTTTCTTAGTGACACTAAAGATCGAGGCCCT
CCAGTGCAGTCACAGATCTGGAGAAGTGGTGAAAAGGTCCCGTTTGTGCAGACATATTCCTTGAGAGCATTTGAGAAACCCCCTCAGGTA
CAGACCCAGGCTCTTCGAGACTTTGAGAAGCACCTCAATGACCTGAAGAAGGAGAACTTCAGCCTCAAGCTGCGCATCTACTTCCTGGAG
GAGCGCATGCAACAGAAGTATGAGGCCAGCCGGGAGGACATCTACAAGCGGAACATTGAGCTGAAGGTTGAAGTGGAGAGCTTGAAACGA
GAACTCCAGGACAAGAAACAGCATCTGGATAAAACATGGGCTGATGTGGAGAATCTCAACAGTCAGAATGAAGCTGAGCTCCGACGCCAG
TTTGAGGAGCGACAGCAGGAGACGGAGCATGTTTATGAGCTCTTGGAGAATAAGATCCAGCTTCTGCAGGAGGAATCCAGGCTAGCAAAG
AATGAAGCTGCGCGGATGGCAGCTCTGGTGGAAGCAGAGAAGGAGTGTAACCTGGAGCTCTCAGAGAAACTGAAGGGAGTCACCAAAAAC
TGGGAAGATGTACCAGGAGACCAGGTCAAGCCCGACCAATACACTGAGGCCCTGGCCCAGAGGGACAAGAGAATTGAAGAACTGAATCAG
AGCCTGGCTGCCCAGGAGAGGCTTGTAGAACAGCTATCTCGGGAGAAACAACAACTGCTACATCTGTTGGAGGAGCCAACTAGCATGGAA
GTGCAGCCCATGACTGAAGAGTTGCTGAAACAACAAAAGCTGAATTCACATGAGACCACTATAACTCAGCAGTCTGTATCTGATTCCCAC
TTGGCAGAACTCCAGGAAAAAATCCAGCAAACAGAGGCCACCAACAAGATTCTTCAAGAGAAACTTAATGAAATGAGCTATGAACTAAAG
TGTGCTCAGGAGTCGTCTCAAAAGCAAGATGGTACAATTCAGAACCTCAAGGAAACTCTGAAAAGCAGGGAACGTGAGACTGAGGAGTTG
TACCAGGTAATTGAAGGTCAAAATGACACAATGGCAAAGCTTCGAGAAATGCTGCACCAAAGCCAGCTTGGACAACTTCACAGCTCAGAG
GGTACTTCTCCAGCTCAGCAACAGGTAGCTCTGCTTGATCTTCAGAGTGCTTTATTCTGCAGCCAACTTGAAATACAGAAGCTCCAGAGG
GTGGTACGACAGAAAGAGCGCCAACTGGCTGATGCCAAACAATGTGTGCAATTTGTAGAGGCTGCAGCACACGAGAGTGAACAGCAGAAA
GAGGCTTCTTGGAAACATAACCAGGAATTGCGAAAAGCCTTGCAGCAGCTACAAGAAGAATTGCAGAATAAGAGCCAACAGCTTCGTGCC
TGGGAGGCTGAAAAATACAATGAGATTCGAACCCAGGAACAAAACATCCAGCACCTAAACCATAGTCTGAGTCACAAGGAGCAGTTGCTT
CAGGAATTTCGGGAGCTCCTACAGTATCGAGATAACTCAGACAAAACCCTTGAAGCAAATGAAATGTTGCTTGAGAAACTTCGCCAGCGA
ATACATGATAAAGCTGTTGCTCTGGAGCGGGCTATAGATGAAAAATTCTCTGCTCTAGAAGAGAAAGAAAAAGAACTGCGCCAGCTTCGT
CTTGCTGTGAGAGAGCGAGATCATGACTTAGAGAGACTGCGCGATGTCCTCTCCTCCAATGAAGCTACTATGCAAAGTATGGAGAGTCTC
CTGAGGGCCAAAGGCCTGGAAGTGGAACAGTTATCTACTACCTGTCAAAACCTCCAGTGGCTGAAAGAAGAAATGGAAACCAAATTTAGC
CGTTGGCAGAAGGAACAAGAGAGTATCATTCAGCAGTTACAGACGTCTCTTCATGATAGGAACAAAGAAGTGGAGGATCTTAGTGCAACA
CTGCTCTGCAAACTTGGACCAGGGCAGAGTGAGATAGCAGAGGAGCTGTGCCAGCGTCTACAGCGAAAGGAAAGGATGCTGCAGGACCTT
CTAAGTGATCGAAATAAACAAGTGCTGGAACATGAAATGGAGATTCAAGGCCTGCTTCAGTCTGTGAGCACCAGGGAGCAGGAAAGCCAA
GCCACAGAGGATGTGGATTACACACAAGTCGTCTTTTCTGACCCTGGAGAACTAAAAAATGACTCCCCGCTGGACTATGAGAACATAAAG
GAAATCACAGATTATGTCAATGTCAATCCAGAAAGACACAAGCCCAGTTTCTGGTATTTTGTCAACCCTGCTCTGTCTGAGCCAGCGGAA
TATGATCAAGTGGCCATGTGAATTCCAAATATTTTTAATGGGGTCCAGTTCTCTATGGATTCTTACATTTAATTTGTAGGGAAATGCCAT
TTTTCCCCCTTAAACAAGGCATGGGGCTCACAAGTCTATGGAGACAGGCCAAAAAGAATGTGGAGAAGAAAACTGATAAATACACAGAGG
TCCTCAAGACCCATGGACTCCTGGTCTGTACCCAAAAAAGCTGTTCGTTCCTCAAAAACAAAAACAAGGCTTGGCTGGGAAAACAGGCCA
ATGCCCCGGCAAGAAAGGTTGAGATCAGATGTTAGGAAGAACTTTCAGGTAAAGTATGAGAACTATGGAGTCCATCAGCAGAGATAGTAG
TGAAGTCTCTCCCCAGGGAAAATTTTAAAAAGGTTGAATCAGCTGTTGTAGAGTTCTATTTGGCAATCTCATGGTTAAATGACTTCCCTT

>63729_63729_9_PDE4DIP-C1orf186_PDE4DIP_chr1_144915445_ENST00000530740_C1orf186_chr1_206239579_ENST00000331555_length(amino acids)=863AA_BP=797
MKGTDSGSCCRRRCDFGCCCRASRRAHYTPYRSGDATRTPQSPRQTPSRERRRPEPAGSWAAAAEEEEAAAAATPWMRDYFAEDDGEMVP
RTSHTAAFLSDTKDRGPPVQSQIWRSGEKVPFVQTYSLRAFEKPPQVQTQALRDFEKHLNDLKKENFSLKLRIYFLEERMQQKYEASRED
IYKRNIELKVEVESLKRELQDKKQHLDKTWADVENLNSQNEAELRRQFEERQQETEHVYELLENKIQLLQEESRLAKNEAARMAALVEAE
KECNLELSEKLKGVTKNWEDVPGDQVKPDQYTEALAQRDKRIEELNQSLAAQERLVEQLSREKQQLLHLLEEPTSMEVQPMTEELLKQQK
LNSHETTITQQSVSDSHLAELQEKIQQTEATNKILQEKLNEMSYELKCAQESSQKQDGTIQNLKETLKSRERETEELYQVIEGQNDTMAK
LREMLHQSQLGQLHSSEGTSPAQQQVALLDLQSALFCSQLEIQKLQRVVRQKERQLADAKQCVQFVEAAAHESEQQKEASWKHNQELRKA
LQQLQEELQNKSQQLRAWEAEKYNEIRTQEQNIQHLNHSLSHKEQLLQEFRELLQYRDNSDKTLEANEMLLEKLRQRIHDKAVALERAID
EKFSALEEKEKELRQLRLAVRERDHDLERLRDVLSSNEATMQSMESLLRAKGLEVEQLSTTCQNLQWLKEEMETKFSRWQKEQESIIQQL
QTSLHDRNKEVEDLSATLLCKLGPGQSEIAEELCQRLQRKERMLQDLLSDRNKQVLEHEMEIQGLLQSVSTREQESQATEDVDYTQVVFS

--------------------------------------------------------------

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Fusion Gene PPI Analysis for PDE4DIP-C1orf186


check button Go to ChiPPI (Chimeric Protein-Protein interactions) to see the chimeric PPI interaction in

ChiPPI page.


check button Protein-protein interactors with each fusion partner protein in wild-type (BIOGRID-3.4.160)
HgeneHgene's interactorsTgeneTgene's interactors


check button - Retained PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenStill interaction with


check button - Lost PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


check button - Retained PPIs, but lost function due to frame-shift fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


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Related Drugs for PDE4DIP-C1orf186


check button Drugs targeting genes involved in this fusion gene.
(DrugBank Version 5.1.8 2021-05-08)
PartnerGeneUniProtAccDrugBank IDDrug nameDrug activityDrug typeDrug status

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Related Diseases for PDE4DIP-C1orf186


check button Diseases associated with fusion partners.
(DisGeNet 4.0)
PartnerGeneDisease IDDisease name# pubmedsSource