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Center for Computational Systems Medicine
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Fusion Gene Summary

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Fusion Gene ORF analysis

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Fusion Genomic Features

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Fusion Protein Features

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Fusion Gene Sequence

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Fusion Gene PPI analysis

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Related Drugs

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Related Diseases

Fusion gene:PDE9A-ABCG1 (FusionGDB2 ID:63815)

Fusion Gene Summary for PDE9A-ABCG1

check button Fusion gene summary
Fusion gene informationFusion gene name: PDE9A-ABCG1
Fusion gene ID: 63815
HgeneTgene
Gene symbol

PDE9A

ABCG1

Gene ID

5152

9619

Gene namephosphodiesterase 9AATP binding cassette subfamily G member 1
SynonymsHSPDE9A2ABC8|WHITE1
Cytomap

21q22.3

21q22.3

Type of geneprotein-codingprotein-coding
Descriptionhigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9ACGMP-specific 3',5'-cyclic phosphodiesterase type 9phosphodiesterase PDE9A21ATP-binding cassette sub-family G member 1ABC transporter 8ATP-binding cassette transporter 8ATP-binding cassette transporter member 1 of subfamily GATP-binding cassette, sub-family G (WHITE), member 1homolog of Drosophila whitewhite protein homolog
Modification date2020032720200329
UniProtAcc.

P45844

Ensembl transtripts involved in fusion geneENST00000470987, ENST00000291539, 
ENST00000328862, ENST00000335440, 
ENST00000335512, ENST00000349112, 
ENST00000380328, ENST00000398224, 
ENST00000398225, ENST00000398227, 
ENST00000398229, ENST00000398232, 
ENST00000398234, ENST00000398236, 
ENST00000539837, 		ENST00000398457, 
ENST00000343687, ENST00000347800, 
ENST00000361802, ENST00000398449, 
ENST00000462050, ENST00000340588, 
ENST00000398437, 
Fusion gene scores* DoF score11 X 7 X 6=4629 X 5 X 8=360
# samples 1110
** MAII scorelog2(11/462*10)=-2.0703893278914
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0		log2(10/360*10)=-1.84799690655495
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0
Context

PubMed: PDE9A [Title/Abstract] AND ABCG1 [Title/Abstract] AND fusion [Title/Abstract]

Most frequent breakpointPDE9A(44073993)-ABCG1(43645781), # samples:3
Anticipated loss of major functional domain due to fusion event.PDE9A-ABCG1 seems lost the major protein functional domain in Hgene partner, which is a cell metabolism gene due to the frame-shifted ORF.
PDE9A-ABCG1 seems lost the major protein functional domain in Hgene partner, which is a IUPHAR drug target due to the frame-shifted ORF.
PDE9A-ABCG1 seems lost the major protein functional domain in Tgene partner, which is a cell metabolism gene due to the frame-shifted ORF.
PDE9A-ABCG1 seems lost the major protein functional domain in Tgene partner, which is a IUPHAR drug target due to the frame-shifted ORF.
* DoF score (Degree of Frequency) = # partners X # break points X # cancer types
** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10)

check button Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez
PartnerGeneGO IDGO termPubMed ID
HgenePDE9A

GO:0046068

cGMP metabolic process

9624146

HgenePDE9A

GO:0046069

cGMP catabolic process

25799991

TgeneABCG1

GO:0008203

cholesterol metabolic process

15994327

TgeneABCG1

GO:0033344

cholesterol efflux

15994327

TgeneABCG1

GO:0033993

response to lipid

16556852

TgeneABCG1

GO:0034436

glycoprotein transport

17293612

TgeneABCG1

GO:0042632

cholesterol homeostasis

15994327

TgeneABCG1

GO:0042987

amyloid precursor protein catabolic process

17293612

TgeneABCG1

GO:0050714

positive regulation of protein secretion

17293612

TgeneABCG1

GO:1902004

positive regulation of amyloid-beta formation

17293612


check buttonFusion gene breakpoints across PDE9A (5'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.
all structure

check buttonFusion gene breakpoints across ABCG1 (3'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.
all structure

check button Fusion gene information from two resources (ChiTars 5.0 and ChimerDB 4.0)
* All genome coordinats were lifted-over on hg19.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
SourceDiseaseSampleHgeneHchrHbpHstrandTgeneTchrTbpTstrand
ChimerDB4LUADTCGA-50-5941-01APDE9Achr21

44073993

-ABCG1chr21

43645781

+
ChimerDB4LUADTCGA-50-5941-01APDE9Achr21

44073993

+ABCG1chr21

43645781

+


Top

Fusion Gene ORF analysis for PDE9A-ABCG1

check button Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
ORFHenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrand
3UTR-3CDSENST00000470987ENST00000398457PDE9Achr21

44073993

+ABCG1chr21

43645781

+
3UTR-3UTRENST00000470987ENST00000343687PDE9Achr21

44073993

+ABCG1chr21

43645781

+
3UTR-3UTRENST00000470987ENST00000347800PDE9Achr21

44073993

+ABCG1chr21

43645781

+
3UTR-3UTRENST00000470987ENST00000361802PDE9Achr21

44073993

+ABCG1chr21

43645781

+
3UTR-3UTRENST00000470987ENST00000398449PDE9Achr21

44073993

+ABCG1chr21

43645781

+
3UTR-3UTRENST00000470987ENST00000462050PDE9Achr21

44073993

+ABCG1chr21

43645781

+
3UTR-intronENST00000470987ENST00000340588PDE9Achr21

44073993

+ABCG1chr21

43645781

+
3UTR-intronENST00000470987ENST00000398437PDE9Achr21

44073993

+ABCG1chr21

43645781

+
5CDS-3UTRENST00000291539ENST00000343687PDE9Achr21

44073993

+ABCG1chr21

43645781

+
5CDS-3UTRENST00000291539ENST00000347800PDE9Achr21

44073993

+ABCG1chr21

43645781

+
5CDS-3UTRENST00000291539ENST00000361802PDE9Achr21

44073993

+ABCG1chr21

43645781

+
5CDS-3UTRENST00000291539ENST00000398449PDE9Achr21

44073993

+ABCG1chr21

43645781

+
5CDS-3UTRENST00000291539ENST00000462050PDE9Achr21

44073993

+ABCG1chr21

43645781

+
5CDS-3UTRENST00000328862ENST00000343687PDE9Achr21

44073993

+ABCG1chr21

43645781

+
5CDS-3UTRENST00000328862ENST00000347800PDE9Achr21

44073993

+ABCG1chr21

43645781

+
5CDS-3UTRENST00000328862ENST00000361802PDE9Achr21

44073993

+ABCG1chr21

43645781

+
5CDS-3UTRENST00000328862ENST00000398449PDE9Achr21

44073993

+ABCG1chr21

43645781

+
5CDS-3UTRENST00000328862ENST00000462050PDE9Achr21

44073993

+ABCG1chr21

43645781

+
5CDS-3UTRENST00000335440ENST00000343687PDE9Achr21

44073993

+ABCG1chr21

43645781

+
5CDS-3UTRENST00000335440ENST00000347800PDE9Achr21

44073993

+ABCG1chr21

43645781

+
5CDS-3UTRENST00000335440ENST00000361802PDE9Achr21

44073993

+ABCG1chr21

43645781

+
5CDS-3UTRENST00000335440ENST00000398449PDE9Achr21

44073993

+ABCG1chr21

43645781

+
5CDS-3UTRENST00000335440ENST00000462050PDE9Achr21

44073993

+ABCG1chr21

43645781

+
5CDS-3UTRENST00000335512ENST00000343687PDE9Achr21

44073993

+ABCG1chr21

43645781

+
5CDS-3UTRENST00000335512ENST00000347800PDE9Achr21

44073993

+ABCG1chr21

43645781

+
5CDS-3UTRENST00000335512ENST00000361802PDE9Achr21

44073993

+ABCG1chr21

43645781

+
5CDS-3UTRENST00000335512ENST00000398449PDE9Achr21

44073993

+ABCG1chr21

43645781

+
5CDS-3UTRENST00000335512ENST00000462050PDE9Achr21

44073993

+ABCG1chr21

43645781

+
5CDS-3UTRENST00000349112ENST00000343687PDE9Achr21

44073993

+ABCG1chr21

43645781

+
5CDS-3UTRENST00000349112ENST00000347800PDE9Achr21

44073993

+ABCG1chr21

43645781

+
5CDS-3UTRENST00000349112ENST00000361802PDE9Achr21

44073993

+ABCG1chr21

43645781

+
5CDS-3UTRENST00000349112ENST00000398449PDE9Achr21

44073993

+ABCG1chr21

43645781

+
5CDS-3UTRENST00000349112ENST00000462050PDE9Achr21

44073993

+ABCG1chr21

43645781

+
5CDS-3UTRENST00000380328ENST00000343687PDE9Achr21

44073993

+ABCG1chr21

43645781

+
5CDS-3UTRENST00000380328ENST00000347800PDE9Achr21

44073993

+ABCG1chr21

43645781

+
5CDS-3UTRENST00000380328ENST00000361802PDE9Achr21

44073993

+ABCG1chr21

43645781

+
5CDS-3UTRENST00000380328ENST00000398449PDE9Achr21

44073993

+ABCG1chr21

43645781

+
5CDS-3UTRENST00000380328ENST00000462050PDE9Achr21

44073993

+ABCG1chr21

43645781

+
5CDS-3UTRENST00000398224ENST00000343687PDE9Achr21

44073993

+ABCG1chr21

43645781

+
5CDS-3UTRENST00000398224ENST00000347800PDE9Achr21

44073993

+ABCG1chr21

43645781

+
5CDS-3UTRENST00000398224ENST00000361802PDE9Achr21

44073993

+ABCG1chr21

43645781

+
5CDS-3UTRENST00000398224ENST00000398449PDE9Achr21

44073993

+ABCG1chr21

43645781

+
5CDS-3UTRENST00000398224ENST00000462050PDE9Achr21

44073993

+ABCG1chr21

43645781

+
5CDS-3UTRENST00000398225ENST00000343687PDE9Achr21

44073993

+ABCG1chr21

43645781

+
5CDS-3UTRENST00000398225ENST00000347800PDE9Achr21

44073993

+ABCG1chr21

43645781

+
5CDS-3UTRENST00000398225ENST00000361802PDE9Achr21

44073993

+ABCG1chr21

43645781

+
5CDS-3UTRENST00000398225ENST00000398449PDE9Achr21

44073993

+ABCG1chr21

43645781

+
5CDS-3UTRENST00000398225ENST00000462050PDE9Achr21

44073993

+ABCG1chr21

43645781

+
5CDS-3UTRENST00000398227ENST00000343687PDE9Achr21

44073993

+ABCG1chr21

43645781

+
5CDS-3UTRENST00000398227ENST00000347800PDE9Achr21

44073993

+ABCG1chr21

43645781

+
5CDS-3UTRENST00000398227ENST00000361802PDE9Achr21

44073993

+ABCG1chr21

43645781

+
5CDS-3UTRENST00000398227ENST00000398449PDE9Achr21

44073993

+ABCG1chr21

43645781

+
5CDS-3UTRENST00000398227ENST00000462050PDE9Achr21

44073993

+ABCG1chr21

43645781

+
5CDS-3UTRENST00000398229ENST00000343687PDE9Achr21

44073993

+ABCG1chr21

43645781

+
5CDS-3UTRENST00000398229ENST00000347800PDE9Achr21

44073993

+ABCG1chr21

43645781

+
5CDS-3UTRENST00000398229ENST00000361802PDE9Achr21

44073993

+ABCG1chr21

43645781

+
5CDS-3UTRENST00000398229ENST00000398449PDE9Achr21

44073993

+ABCG1chr21

43645781

+
5CDS-3UTRENST00000398229ENST00000462050PDE9Achr21

44073993

+ABCG1chr21

43645781

+
5CDS-3UTRENST00000398232ENST00000343687PDE9Achr21

44073993

+ABCG1chr21

43645781

+
5CDS-3UTRENST00000398232ENST00000347800PDE9Achr21

44073993

+ABCG1chr21

43645781

+
5CDS-3UTRENST00000398232ENST00000361802PDE9Achr21

44073993

+ABCG1chr21

43645781

+
5CDS-3UTRENST00000398232ENST00000398449PDE9Achr21

44073993

+ABCG1chr21

43645781

+
5CDS-3UTRENST00000398232ENST00000462050PDE9Achr21

44073993

+ABCG1chr21

43645781

+
5CDS-3UTRENST00000398234ENST00000343687PDE9Achr21

44073993

+ABCG1chr21

43645781

+
5CDS-3UTRENST00000398234ENST00000347800PDE9Achr21

44073993

+ABCG1chr21

43645781

+
5CDS-3UTRENST00000398234ENST00000361802PDE9Achr21

44073993

+ABCG1chr21

43645781

+
5CDS-3UTRENST00000398234ENST00000398449PDE9Achr21

44073993

+ABCG1chr21

43645781

+
5CDS-3UTRENST00000398234ENST00000462050PDE9Achr21

44073993

+ABCG1chr21

43645781

+
5CDS-3UTRENST00000398236ENST00000343687PDE9Achr21

44073993

+ABCG1chr21

43645781

+
5CDS-3UTRENST00000398236ENST00000347800PDE9Achr21

44073993

+ABCG1chr21

43645781

+
5CDS-3UTRENST00000398236ENST00000361802PDE9Achr21

44073993

+ABCG1chr21

43645781

+
5CDS-3UTRENST00000398236ENST00000398449PDE9Achr21

44073993

+ABCG1chr21

43645781

+
5CDS-3UTRENST00000398236ENST00000462050PDE9Achr21

44073993

+ABCG1chr21

43645781

+
5CDS-intronENST00000291539ENST00000340588PDE9Achr21

44073993

+ABCG1chr21

43645781

+
5CDS-intronENST00000291539ENST00000398437PDE9Achr21

44073993

+ABCG1chr21

43645781

+
5CDS-intronENST00000328862ENST00000340588PDE9Achr21

44073993

+ABCG1chr21

43645781

+
5CDS-intronENST00000328862ENST00000398437PDE9Achr21

44073993

+ABCG1chr21

43645781

+
5CDS-intronENST00000335440ENST00000340588PDE9Achr21

44073993

+ABCG1chr21

43645781

+
5CDS-intronENST00000335440ENST00000398437PDE9Achr21

44073993

+ABCG1chr21

43645781

+
5CDS-intronENST00000335512ENST00000340588PDE9Achr21

44073993

+ABCG1chr21

43645781

+
5CDS-intronENST00000335512ENST00000398437PDE9Achr21

44073993

+ABCG1chr21

43645781

+
5CDS-intronENST00000349112ENST00000340588PDE9Achr21

44073993

+ABCG1chr21

43645781

+
5CDS-intronENST00000349112ENST00000398437PDE9Achr21

44073993

+ABCG1chr21

43645781

+
5CDS-intronENST00000380328ENST00000340588PDE9Achr21

44073993

+ABCG1chr21

43645781

+
5CDS-intronENST00000380328ENST00000398437PDE9Achr21

44073993

+ABCG1chr21

43645781

+
5CDS-intronENST00000398224ENST00000340588PDE9Achr21

44073993

+ABCG1chr21

43645781

+
5CDS-intronENST00000398224ENST00000398437PDE9Achr21

44073993

+ABCG1chr21

43645781

+
5CDS-intronENST00000398225ENST00000340588PDE9Achr21

44073993

+ABCG1chr21

43645781

+
5CDS-intronENST00000398225ENST00000398437PDE9Achr21

44073993

+ABCG1chr21

43645781

+
5CDS-intronENST00000398227ENST00000340588PDE9Achr21

44073993

+ABCG1chr21

43645781

+
5CDS-intronENST00000398227ENST00000398437PDE9Achr21

44073993

+ABCG1chr21

43645781

+
5CDS-intronENST00000398229ENST00000340588PDE9Achr21

44073993

+ABCG1chr21

43645781

+
5CDS-intronENST00000398229ENST00000398437PDE9Achr21

44073993

+ABCG1chr21

43645781

+
5CDS-intronENST00000398232ENST00000340588PDE9Achr21

44073993

+ABCG1chr21

43645781

+
5CDS-intronENST00000398232ENST00000398437PDE9Achr21

44073993

+ABCG1chr21

43645781

+
5CDS-intronENST00000398234ENST00000340588PDE9Achr21

44073993

+ABCG1chr21

43645781

+
5CDS-intronENST00000398234ENST00000398437PDE9Achr21

44073993

+ABCG1chr21

43645781

+
5CDS-intronENST00000398236ENST00000340588PDE9Achr21

44073993

+ABCG1chr21

43645781

+
5CDS-intronENST00000398236ENST00000398437PDE9Achr21

44073993

+ABCG1chr21

43645781

+
5UTR-3CDSENST00000539837ENST00000398457PDE9Achr21

44073993

+ABCG1chr21

43645781

+
5UTR-3UTRENST00000539837ENST00000343687PDE9Achr21

44073993

+ABCG1chr21

43645781

+
5UTR-3UTRENST00000539837ENST00000347800PDE9Achr21

44073993

+ABCG1chr21

43645781

+
5UTR-3UTRENST00000539837ENST00000361802PDE9Achr21

44073993

+ABCG1chr21

43645781

+
5UTR-3UTRENST00000539837ENST00000398449PDE9Achr21

44073993

+ABCG1chr21

43645781

+
5UTR-3UTRENST00000539837ENST00000462050PDE9Achr21

44073993

+ABCG1chr21

43645781

+
5UTR-intronENST00000539837ENST00000340588PDE9Achr21

44073993

+ABCG1chr21

43645781

+
5UTR-intronENST00000539837ENST00000398437PDE9Achr21

44073993

+ABCG1chr21

43645781

+
Frame-shiftENST00000398224ENST00000398457PDE9Achr21

44073993

+ABCG1chr21

43645781

+
Frame-shiftENST00000398225ENST00000398457PDE9Achr21

44073993

+ABCG1chr21

43645781

+
Frame-shiftENST00000398227ENST00000398457PDE9Achr21

44073993

+ABCG1chr21

43645781

+
Frame-shiftENST00000398229ENST00000398457PDE9Achr21

44073993

+ABCG1chr21

43645781

+
Frame-shiftENST00000398232ENST00000398457PDE9Achr21

44073993

+ABCG1chr21

43645781

+
Frame-shiftENST00000398234ENST00000398457PDE9Achr21

44073993

+ABCG1chr21

43645781

+
In-frameENST00000291539ENST00000398457PDE9Achr21

44073993

+ABCG1chr21

43645781

+
In-frameENST00000328862ENST00000398457PDE9Achr21

44073993

+ABCG1chr21

43645781

+
In-frameENST00000335440ENST00000398457PDE9Achr21

44073993

+ABCG1chr21

43645781

+
In-frameENST00000335512ENST00000398457PDE9Achr21

44073993

+ABCG1chr21

43645781

+
In-frameENST00000349112ENST00000398457PDE9Achr21

44073993

+ABCG1chr21

43645781

+
In-frameENST00000380328ENST00000398457PDE9Achr21

44073993

+ABCG1chr21

43645781

+
In-frameENST00000398236ENST00000398457PDE9Achr21

44073993

+ABCG1chr21

43645781

+

check buttonORFfinder result based on the fusion transcript sequence of in-frame fusion genes.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandSeq length
(transcript)		BP loci
(transcript)		Predicted start
(transcript)		Predicted stop
(transcript)		Seq length
(amino acids)
ENST00000335512PDE9Achr2144073993+ENST00000398457ABCG1chr2143645781+2945134652092675
ENST00000291539PDE9Achr2144073993+ENST00000398457ABCG1chr2143645781+2940129602087675
ENST00000398236PDE9Achr2144073993+ENST00000398457ABCG1chr2143645781+2916105362063675
ENST00000380328PDE9Achr2144073993+ENST00000398457ABCG1chr2143645781+2916105362063675
ENST00000328862PDE9Achr2144073993+ENST00000398457ABCG1chr2143645781+2916105362063675
ENST00000335440PDE9Achr2144073993+ENST00000398457ABCG1chr2143645781+2916105362063675
ENST00000349112PDE9Achr2144073993+ENST00000398457ABCG1chr2143645781+28827122029675

check buttonDeepORF prediction of the coding potential based on the fusion transcript sequence of in-frame fusion genes. DeepORF is a coding potential classifier based on convolutional neural network by comparing the real Ribo-seq data. If the no-coding score < 0.5 and coding score > 0.5, then the in-frame fusion transcript is predicted as being likely translated.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandNo-coding scoreCoding score
ENST00000335512ENST00000398457PDE9Achr2144073993+ABCG1chr2143645781+0.0035110860.9964889
ENST00000291539ENST00000398457PDE9Achr2144073993+ABCG1chr2143645781+0.0034920220.99650794
ENST00000398236ENST00000398457PDE9Achr2144073993+ABCG1chr2143645781+0.0035390020.996461
ENST00000380328ENST00000398457PDE9Achr2144073993+ABCG1chr2143645781+0.0035390020.996461
ENST00000328862ENST00000398457PDE9Achr2144073993+ABCG1chr2143645781+0.0035390020.996461
ENST00000335440ENST00000398457PDE9Achr2144073993+ABCG1chr2143645781+0.0035390020.996461
ENST00000349112ENST00000398457PDE9Achr2144073993+ABCG1chr2143645781+0.0035592770.9964407

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Fusion Genomic Features for PDE9A-ABCG1


check buttonFusionAI prediction of the potential fusion gene breakpoint based on the pre-mature RNA sequence context (+/- 5kb of individual partner genes, total 20kb length sequence). FusionAI is a fusion gene breakpoint classifier based on convolutional neural network by comparing the fusion positive and negative sequence context of ~ 20K fusion gene data. From here, we can have the relative potentency of the 20K genomic sequence how individual sequnce will be likely used as the gene fusion breakpoints.
HgeneHchrHbpHstrandTgeneTchrTbpTstrand1-pp (fusion gene breakpoint)
PDE9Achr2144073993+ABCG1chr2143645780+2.19E-081
PDE9Achr2144073993+ABCG1chr2143645780+2.19E-081

check buttonDistribution of 44 human genomic features loci across 20kb length fusion breakpoint regions. We integrated a total of 44 different types of human genomic feature loci information across five big categories including virus integration sites, repeats, structural variants, chromatin states, and gene expression regulation. More details are in help page.
genomic feature

check buttonDistribution of 44 human genomic features loci across 20kb length fusion breakpoint regions that are ovelapped with the top 1% feature importance score regions. More details are in help page.
genomic feature of top 1%

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Fusion Protein Features for PDE9A-ABCG1


check button Four levels of functional features of fusion genes
Go to FGviewer search page for the most frequent breakpoint (https://ccsmweb.uth.edu/FGviewer/chr21:44073993/chr21:43645781)
- FGviewer provides the online visualization of the retention search of the protein functional features across DNA, RNA, protein, and pathological levels.
- How to search
1. Put your fusion gene symbol.
2. Press the tab key until there will be shown the breakpoint information filled.
4. Go down and press 'Search' tab twice.
4. Go down to have the hyperlink of the search result.
5. Click the hyperlink.
6. See the FGviewer result for your fusion gene.
FGviewer

check buttonMain function of each fusion partner protein. (from UniProt)
HgeneTgene
.ABCG1

P45844

FUNCTION: Transcriptional activator which is required for calcium-dependent dendritic growth and branching in cortical neurons. Recruits CREB-binding protein (CREBBP) to nuclear bodies. Component of the CREST-BRG1 complex, a multiprotein complex that regulates promoter activation by orchestrating a calcium-dependent release of a repressor complex and a recruitment of an activator complex. In resting neurons, transcription of the c-FOS promoter is inhibited by BRG1-dependent recruitment of a phospho-RB1-HDAC1 repressor complex. Upon calcium influx, RB1 is dephosphorylated by calcineurin, which leads to release of the repressor complex. At the same time, there is increased recruitment of CREBBP to the promoter by a CREST-dependent mechanism, which leads to transcriptional activation. The CREST-BRG1 complex also binds to the NR2B promoter, and activity-dependent induction of NR2B expression involves a release of HDAC1 and recruitment of CREBBP (By similarity). {ECO:0000250}.FUNCTION: Catalyzes the efflux of phospholipids such as sphingomyelin, cholesterol and its oxygenated derivatives like 7beta-hydroxycholesterol and this transport is coupled to hydrlysis of ATP (PubMed:17408620, PubMed:24576892). The lipid efflux is ALB-dependent (PubMed:16702602). Is an active component of the macrophage lipid export complex. Could also be involved in intracellular lipid transport processes. The role in cellular lipid homeostasis may not be limited to macrophages. Prevents cell death by transporting cytotoxic 7beta-hydroxycholesterol (PubMed:17408620). {ECO:0000269|PubMed:16702602, ECO:0000269|PubMed:17408620, ECO:0000269|PubMed:24576892}.

check buttonRetention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at

download page


* Minus value of BPloci means that the break pointn is located before the CDS.
- In-frame and retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
TgeneABCG1chr21:44073993chr21:43645781ENST00000343687015415_67325678.0DomainNote=ABC transmembrane type-2
TgeneABCG1chr21:44073993chr21:43645781ENST0000034368701577_31725678.0DomainABC transporter
TgeneABCG1chr21:44073993chr21:43645781ENST00000347800015415_67311664.0DomainNote=ABC transmembrane type-2
TgeneABCG1chr21:44073993chr21:43645781ENST0000034780001577_31711664.0DomainABC transporter
TgeneABCG1chr21:44073993chr21:43645781ENST00000361802015415_67314679.0DomainNote=ABC transmembrane type-2
TgeneABCG1chr21:44073993chr21:43645781ENST0000036180201577_31714679.0DomainABC transporter
TgeneABCG1chr21:44073993chr21:43645781ENST00000398449015415_67314667.0DomainNote=ABC transmembrane type-2
TgeneABCG1chr21:44073993chr21:43645781ENST0000039844901577_31714667.0DomainABC transporter
TgeneABCG1chr21:44073993chr21:43645781ENST00000398457116415_67316669.0DomainNote=ABC transmembrane type-2
TgeneABCG1chr21:44073993chr21:43645781ENST0000039845711677_31716669.0DomainABC transporter
TgeneABCG1chr21:44073993chr21:43645781ENST00000343687015118_12525678.0Nucleotide bindingATP
TgeneABCG1chr21:44073993chr21:43645781ENST00000347800015118_12511664.0Nucleotide bindingATP
TgeneABCG1chr21:44073993chr21:43645781ENST00000361802015118_12514679.0Nucleotide bindingATP
TgeneABCG1chr21:44073993chr21:43645781ENST00000398449015118_12514667.0Nucleotide bindingATP
TgeneABCG1chr21:44073993chr21:43645781ENST00000398457116118_12516669.0Nucleotide bindingATP
TgeneABCG1chr21:44073993chr21:43645781ENST00000343687015446_45625678.0Topological domainExtracellular
TgeneABCG1chr21:44073993chr21:43645781ENST00000343687015478_50625678.0Topological domainCytoplasmic
TgeneABCG1chr21:44073993chr21:43645781ENST00000343687015526_53325678.0Topological domainExtracellular
TgeneABCG1chr21:44073993chr21:43645781ENST00000343687015556_56725678.0Topological domainCytoplasmic
TgeneABCG1chr21:44073993chr21:43645781ENST00000343687015587_64925678.0Topological domainExtracellular
TgeneABCG1chr21:44073993chr21:43645781ENST00000343687015670_67825678.0Topological domainCytoplasmic
TgeneABCG1chr21:44073993chr21:43645781ENST00000347800015446_45611664.0Topological domainExtracellular
TgeneABCG1chr21:44073993chr21:43645781ENST00000347800015478_50611664.0Topological domainCytoplasmic
TgeneABCG1chr21:44073993chr21:43645781ENST00000347800015526_53311664.0Topological domainExtracellular
TgeneABCG1chr21:44073993chr21:43645781ENST00000347800015556_56711664.0Topological domainCytoplasmic
TgeneABCG1chr21:44073993chr21:43645781ENST00000347800015587_64911664.0Topological domainExtracellular
TgeneABCG1chr21:44073993chr21:43645781ENST00000347800015670_67811664.0Topological domainCytoplasmic
TgeneABCG1chr21:44073993chr21:43645781ENST00000361802015446_45614679.0Topological domainExtracellular
TgeneABCG1chr21:44073993chr21:43645781ENST00000361802015478_50614679.0Topological domainCytoplasmic
TgeneABCG1chr21:44073993chr21:43645781ENST00000361802015526_53314679.0Topological domainExtracellular
TgeneABCG1chr21:44073993chr21:43645781ENST00000361802015556_56714679.0Topological domainCytoplasmic
TgeneABCG1chr21:44073993chr21:43645781ENST00000361802015587_64914679.0Topological domainExtracellular
TgeneABCG1chr21:44073993chr21:43645781ENST00000361802015670_67814679.0Topological domainCytoplasmic
TgeneABCG1chr21:44073993chr21:43645781ENST00000398449015446_45614667.0Topological domainExtracellular
TgeneABCG1chr21:44073993chr21:43645781ENST00000398449015478_50614667.0Topological domainCytoplasmic
TgeneABCG1chr21:44073993chr21:43645781ENST00000398449015526_53314667.0Topological domainExtracellular
TgeneABCG1chr21:44073993chr21:43645781ENST00000398449015556_56714667.0Topological domainCytoplasmic
TgeneABCG1chr21:44073993chr21:43645781ENST00000398449015587_64914667.0Topological domainExtracellular
TgeneABCG1chr21:44073993chr21:43645781ENST00000398449015670_67814667.0Topological domainCytoplasmic
TgeneABCG1chr21:44073993chr21:43645781ENST00000398457116446_45616669.0Topological domainExtracellular
TgeneABCG1chr21:44073993chr21:43645781ENST00000398457116478_50616669.0Topological domainCytoplasmic
TgeneABCG1chr21:44073993chr21:43645781ENST00000398457116526_53316669.0Topological domainExtracellular
TgeneABCG1chr21:44073993chr21:43645781ENST00000398457116556_56716669.0Topological domainCytoplasmic
TgeneABCG1chr21:44073993chr21:43645781ENST00000398457116587_64916669.0Topological domainExtracellular
TgeneABCG1chr21:44073993chr21:43645781ENST00000398457116670_67816669.0Topological domainCytoplasmic
TgeneABCG1chr21:44073993chr21:43645781ENST00000343687015427_44525678.0TransmembraneHelical
TgeneABCG1chr21:44073993chr21:43645781ENST00000343687015457_47725678.0TransmembraneHelical
TgeneABCG1chr21:44073993chr21:43645781ENST00000343687015507_52525678.0TransmembraneHelical
TgeneABCG1chr21:44073993chr21:43645781ENST00000343687015534_55525678.0TransmembraneHelical
TgeneABCG1chr21:44073993chr21:43645781ENST00000343687015568_58625678.0TransmembraneHelical
TgeneABCG1chr21:44073993chr21:43645781ENST00000343687015650_66925678.0TransmembraneHelical
TgeneABCG1chr21:44073993chr21:43645781ENST00000347800015427_44511664.0TransmembraneHelical
TgeneABCG1chr21:44073993chr21:43645781ENST00000347800015457_47711664.0TransmembraneHelical
TgeneABCG1chr21:44073993chr21:43645781ENST00000347800015507_52511664.0TransmembraneHelical
TgeneABCG1chr21:44073993chr21:43645781ENST00000347800015534_55511664.0TransmembraneHelical
TgeneABCG1chr21:44073993chr21:43645781ENST00000347800015568_58611664.0TransmembraneHelical
TgeneABCG1chr21:44073993chr21:43645781ENST00000347800015650_66911664.0TransmembraneHelical
TgeneABCG1chr21:44073993chr21:43645781ENST00000361802015427_44514679.0TransmembraneHelical
TgeneABCG1chr21:44073993chr21:43645781ENST00000361802015457_47714679.0TransmembraneHelical
TgeneABCG1chr21:44073993chr21:43645781ENST00000361802015507_52514679.0TransmembraneHelical
TgeneABCG1chr21:44073993chr21:43645781ENST00000361802015534_55514679.0TransmembraneHelical
TgeneABCG1chr21:44073993chr21:43645781ENST00000361802015568_58614679.0TransmembraneHelical
TgeneABCG1chr21:44073993chr21:43645781ENST00000361802015650_66914679.0TransmembraneHelical
TgeneABCG1chr21:44073993chr21:43645781ENST00000398449015427_44514667.0TransmembraneHelical
TgeneABCG1chr21:44073993chr21:43645781ENST00000398449015457_47714667.0TransmembraneHelical
TgeneABCG1chr21:44073993chr21:43645781ENST00000398449015507_52514667.0TransmembraneHelical
TgeneABCG1chr21:44073993chr21:43645781ENST00000398449015534_55514667.0TransmembraneHelical
TgeneABCG1chr21:44073993chr21:43645781ENST00000398449015568_58614667.0TransmembraneHelical
TgeneABCG1chr21:44073993chr21:43645781ENST00000398449015650_66914667.0TransmembraneHelical
TgeneABCG1chr21:44073993chr21:43645781ENST00000398457116427_44516669.0TransmembraneHelical
TgeneABCG1chr21:44073993chr21:43645781ENST00000398457116457_47716669.0TransmembraneHelical
TgeneABCG1chr21:44073993chr21:43645781ENST00000398457116507_52516669.0TransmembraneHelical
TgeneABCG1chr21:44073993chr21:43645781ENST00000398457116534_55516669.0TransmembraneHelical
TgeneABCG1chr21:44073993chr21:43645781ENST00000398457116568_58616669.0TransmembraneHelical
TgeneABCG1chr21:44073993chr21:43645781ENST00000398457116650_66916669.0TransmembraneHelical

- In-frame and not-retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
HgenePDE9Achr21:44073993chr21:43645781ENST00000291539+120236_55723594.0DomainPDEase
HgenePDE9Achr21:44073993chr21:43645781ENST00000328862+119236_55723568.0DomainPDEase
HgenePDE9Achr21:44073993chr21:43645781ENST00000335440+117236_55723492.0DomainPDEase
HgenePDE9Achr21:44073993chr21:43645781ENST00000335512+119236_55723534.0DomainPDEase
HgenePDE9Achr21:44073993chr21:43645781ENST00000349112+116236_55723466.0DomainPDEase
HgenePDE9Achr21:44073993chr21:43645781ENST00000380328+119236_55723541.0DomainPDEase
HgenePDE9Achr21:44073993chr21:43645781ENST00000398224+117236_5575467.0DomainPDEase
HgenePDE9Achr21:44073993chr21:43645781ENST00000398225+119236_5575553.0DomainPDEase
HgenePDE9Achr21:44073993chr21:43645781ENST00000398227+115236_5575434.0DomainPDEase
HgenePDE9Achr21:44073993chr21:43645781ENST00000398229+116236_5575460.0DomainPDEase
HgenePDE9Achr21:44073993chr21:43645781ENST00000398232+118236_5575527.0DomainPDEase
HgenePDE9Achr21:44073993chr21:43645781ENST00000398234+118236_5575493.0DomainPDEase
HgenePDE9Achr21:44073993chr21:43645781ENST00000398236+118236_55723508.0DomainPDEase
HgenePDE9Achr21:44073993chr21:43645781ENST00000291539+120312_31623594.0Nucleotide binding3'%2C5'-cGMP
HgenePDE9Achr21:44073993chr21:43645781ENST00000291539+120512_51323594.0Nucleotide binding3'%2C5'-cGMP
HgenePDE9Achr21:44073993chr21:43645781ENST00000328862+119312_31623568.0Nucleotide binding3'%2C5'-cGMP
HgenePDE9Achr21:44073993chr21:43645781ENST00000328862+119512_51323568.0Nucleotide binding3'%2C5'-cGMP
HgenePDE9Achr21:44073993chr21:43645781ENST00000335440+117312_31623492.0Nucleotide binding3'%2C5'-cGMP
HgenePDE9Achr21:44073993chr21:43645781ENST00000335440+117512_51323492.0Nucleotide binding3'%2C5'-cGMP
HgenePDE9Achr21:44073993chr21:43645781ENST00000335512+119312_31623534.0Nucleotide binding3'%2C5'-cGMP
HgenePDE9Achr21:44073993chr21:43645781ENST00000335512+119512_51323534.0Nucleotide binding3'%2C5'-cGMP
HgenePDE9Achr21:44073993chr21:43645781ENST00000349112+116312_31623466.0Nucleotide binding3'%2C5'-cGMP
HgenePDE9Achr21:44073993chr21:43645781ENST00000349112+116512_51323466.0Nucleotide binding3'%2C5'-cGMP
HgenePDE9Achr21:44073993chr21:43645781ENST00000380328+119312_31623541.0Nucleotide binding3'%2C5'-cGMP
HgenePDE9Achr21:44073993chr21:43645781ENST00000380328+119512_51323541.0Nucleotide binding3'%2C5'-cGMP
HgenePDE9Achr21:44073993chr21:43645781ENST00000398224+117312_3165467.0Nucleotide binding3'%2C5'-cGMP
HgenePDE9Achr21:44073993chr21:43645781ENST00000398224+117512_5135467.0Nucleotide binding3'%2C5'-cGMP
HgenePDE9Achr21:44073993chr21:43645781ENST00000398225+119312_3165553.0Nucleotide binding3'%2C5'-cGMP
HgenePDE9Achr21:44073993chr21:43645781ENST00000398225+119512_5135553.0Nucleotide binding3'%2C5'-cGMP
HgenePDE9Achr21:44073993chr21:43645781ENST00000398227+115312_3165434.0Nucleotide binding3'%2C5'-cGMP
HgenePDE9Achr21:44073993chr21:43645781ENST00000398227+115512_5135434.0Nucleotide binding3'%2C5'-cGMP
HgenePDE9Achr21:44073993chr21:43645781ENST00000398229+116312_3165460.0Nucleotide binding3'%2C5'-cGMP
HgenePDE9Achr21:44073993chr21:43645781ENST00000398229+116512_5135460.0Nucleotide binding3'%2C5'-cGMP
HgenePDE9Achr21:44073993chr21:43645781ENST00000398232+118312_3165527.0Nucleotide binding3'%2C5'-cGMP
HgenePDE9Achr21:44073993chr21:43645781ENST00000398232+118512_5135527.0Nucleotide binding3'%2C5'-cGMP
HgenePDE9Achr21:44073993chr21:43645781ENST00000398234+118312_3165493.0Nucleotide binding3'%2C5'-cGMP
HgenePDE9Achr21:44073993chr21:43645781ENST00000398234+118512_5135493.0Nucleotide binding3'%2C5'-cGMP
HgenePDE9Achr21:44073993chr21:43645781ENST00000398236+118312_31623508.0Nucleotide binding3'%2C5'-cGMP
HgenePDE9Achr21:44073993chr21:43645781ENST00000398236+118512_51323508.0Nucleotide binding3'%2C5'-cGMP
TgeneABCG1chr21:44073993chr21:43645781ENST000003436870151_42625678.0Topological domainCytoplasmic
TgeneABCG1chr21:44073993chr21:43645781ENST000003478000151_42611664.0Topological domainCytoplasmic
TgeneABCG1chr21:44073993chr21:43645781ENST000003618020151_42614679.0Topological domainCytoplasmic
TgeneABCG1chr21:44073993chr21:43645781ENST000003984490151_42614667.0Topological domainCytoplasmic
TgeneABCG1chr21:44073993chr21:43645781ENST000003984571161_42616669.0Topological domainCytoplasmic


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Fusion Gene Sequence for PDE9A-ABCG1


check button For in-frame fusion transcripts, we provide the fusion transcript sequences and fusion amino acid sequences. To have fusion amino acid sequence, we ran ORFfinder and chose the longest ORF among the all predicted ones.
>63815_63815_1_PDE9A-ABCG1_PDE9A_chr21_44073993_ENST00000291539_ABCG1_chr21_43645781_ENST00000398457_length(transcript)=2940nt_BP=129nt
CGCGGCGGCTGGCGTCGGGAAAGTACAGTAAAAAGTCCGAGTGCAGCCGCCGGGCGCAGGATGGGATCCGGCTCCTCCAGCTACCGGCCC
AAGGCCATCTACCTGGACATCGATGGACGCATTCAGAAGAATGCCAGCAGTTACTCTGCAGAGATGACGGAGCCCAAGTCGGTGTGTGTC
TCGGTGGATGAGGTGGTGTCCAGCAACATGGAGGCCACTGAGACGGACCTGCTGAATGGACATCTGAAAAAAGTAGATAATAACCTCACG
GAAGCCCAGCGCTTCTCCTCCTTGCCTCGGAGGGCAGCTGTGAACATTGAATTCAGGGACCTTTCCTATTCGGTTCCTGAAGGACCCTGG
TGGAGGAAGAAAGGATACAAGACCCTCCTGAAAGGAATTTCCGGGAAGTTCAATAGTGGTGAGTTGGTGGCCATTATGGGTCCTTCCGGG
GCCGGGAAGTCCACGCTGATGAACATCCTGGCTGGATACAGGGAGACGGGCATGAAGGGGGCCGTCCTCATCAACGGCCTGCCCCGGGAC
CTGCGCTGCTTCCGGAAGGTGTCCTGCTACATCATGCAGGATGACATGCTGCTGCCGCATCTCACTGTGCAGGAGGCCATGATGGTGTCG
GCACATCTGAAGCTTCAGGAGAAGGATGAAGGCAGAAGGGAAATGGTCAAGGAGATACTGACAGCGCTGGGCTTGCTGTCTTGCGCCAAC
ACGCGGACCGGGAGCCTGTCAGGTGGTCAGCGCAAGCGCCTGGCCATCGCGCTGGAGCTGGTGAACAACCCTCCAGTCATGTTCTTCGAT
GAGCCCACCAGCGGCCTGGACAGCGCCTCCTGCTTCCAGGTGGTCTCGCTGATGAAAGGGCTCGCTCAAGGGGGTCGCTCCATCATTTGC
ACCATCCACCAGCCCAGCGCCAAACTCTTCGAGCTGTTCGACCAGCTTTACGTCCTGAGTCAAGGACAATGTGTGTACCGGGGAAAAGTC
TGCAATCTTGTGCCATATTTGAGGGATTTGGGTCTGAACTGCCCAACCTACCACAACCCAGCAGATTTTGTCATGGAGGTTGCATCCGGC
GAGTACGGTGATCAGAACAGTCGGCTGGTGAGAGCGGTTCGGGAGGGCATGTGTGACTCAGACCACAAGAGAGACCTCGGGGGTGATGCC
GAGGTGAACCCTTTTCTTTGGCACCGGCCCTCTGAAGAGGACTCCTCGTCCATGGAAGGCTGCCACAGCTTCTCTGCCAGCTGCCTCACG
CAGTTCTGCATCCTCTTCAAGAGGACCTTCCTCAGCATCATGAGGGACTCGGTCCTGACACACCTGCGCATCACCTCGCACATTGGGATC
GGCCTCCTCATTGGCCTGCTGTACTTGGGGATCGGGAACGAAGCCAAGAAGGTCTTGAGCAACTCCGGCTTCCTCTTCTTCTCCATGCTG
TTCCTCATGTTCGCGGCCCTCATGCCTACTGTTCTGACATTTCCCCTGGAGATGGGAGTCTTTCTTCGGGAACACCTGAACTACTGGTAC
AGCCTGAAGGCCTACTACCTGGCCAAGACCATGGCAGACGTGCCCTTTCAGATCATGTTCCCAGTGGCCTACTGCAGCATCGTGTACTGG
ATGACGTCGCAGCCGTCCGACGCCGTGCGCTTTGTGCTGTTTGCCGCGCTGGGCACCATGACCTCCCTGGTGGCACAGTCCCTGGGCCTG
CTGATCGGAGCCGCCTCCACGTCCCTGCAGGTGGCCACTTTCGTGGGCCCAGTGACAGCCATCCCGGTGCTCCTGTTCTCGGGGTTCTTC
GTCAGCTTCGACACCATCCCCACGTACCTACAGTGGATGTCCTACATCTCCTATGTCAGGTATGGGTTCGAAGGGGTCATCCTCTCCATC
TATGGCTTAGACCGGGAAGATCTGCACTGTGACATCGACGAGACGTGCCACTTCCAGAAGTCGGAGGCCATCCTGCGGGAGCTGGACGTG
GAAAATGCCAAGCTGTACCTGGACTTCATCGTACTCGGGATTTTCTTCATCTCCCTCCGCCTCATTGCCTATTTTGTCCTCAGGTACAAA
ATCCGGGCAGAGAGGTAAAACACCTGAATGCCAGGAAACAGGAAGATTAGACACTGTGGCCGAGGGCACGTCTAGAATCGAGGAGGCAAG
CCTGTGCCCGACCGACGACACAGAGACTCTTCTGATCCAACCCCTAGAACCGCGTTGGGTTTGTGGGTGTCTCGTGCTCAGCCACTCTGC
CCAGCTGGGTTGGATCTTCTCTCCATTCCCCTTTCTAGCTTTAACTAGGAAGATGTAGGCAGATTGGTGGTTTTTTTTTTTTTAACATAC
AGAATTTTAAATACCACAACTGGGGCAGAATTTAAAGCTGCAACACAGCTGGTGATGAGAGGCTTCCTCAGTCCAGTCGCTCCTTAGCAC
CAGGCACCGTGGGTCCTGGATGGGGAACTGCAAGCAGCCTCTCAGCTGATGGCTGCACAGTCAGATGTCTGGTGGCAGAGAGTCCGAGCA
TGGAGCGATTCCATTTTATGACTGTTGTTTTTCACATTTTCATCTTTCTAAGGTGTGTCTCTTTTCCAATGAGAAGTCATTTTTGCAAGC
CAAAAGTCGATCAATCGCATTCATTTTAAGAAATTATACCTTTTTAGTACTTGCTGAAGAATGATTCAGGGTAAATCACATACTTTGTTT
AGAGAGGCGAGGGGTTTAACCGAGTCACCCAGCTGGTCTCATACATAGACAGCACTTGTGAAGGATTGAATGCAGGTTCCAGGTGGAGGG
AAGACGTGGACACCATCTCCACTGAGCCATGCAGACATTTTTAAAAGCTATACAAAAAATTGTGAGAAGACATTGGCCAACTCTTTCAAA

>63815_63815_1_PDE9A-ABCG1_PDE9A_chr21_44073993_ENST00000291539_ABCG1_chr21_43645781_ENST00000398457_length(amino acids)=675AA_BP=23
MGSGSSSYRPKAIYLDIDGRIQKNASSYSAEMTEPKSVCVSVDEVVSSNMEATETDLLNGHLKKVDNNLTEAQRFSSLPRRAAVNIEFRD
LSYSVPEGPWWRKKGYKTLLKGISGKFNSGELVAIMGPSGAGKSTLMNILAGYRETGMKGAVLINGLPRDLRCFRKVSCYIMQDDMLLPH
LTVQEAMMVSAHLKLQEKDEGRREMVKEILTALGLLSCANTRTGSLSGGQRKRLAIALELVNNPPVMFFDEPTSGLDSASCFQVVSLMKG
LAQGGRSIICTIHQPSAKLFELFDQLYVLSQGQCVYRGKVCNLVPYLRDLGLNCPTYHNPADFVMEVASGEYGDQNSRLVRAVREGMCDS
DHKRDLGGDAEVNPFLWHRPSEEDSSSMEGCHSFSASCLTQFCILFKRTFLSIMRDSVLTHLRITSHIGIGLLIGLLYLGIGNEAKKVLS
NSGFLFFSMLFLMFAALMPTVLTFPLEMGVFLREHLNYWYSLKAYYLAKTMADVPFQIMFPVAYCSIVYWMTSQPSDAVRFVLFAALGTM
TSLVAQSLGLLIGAASTSLQVATFVGPVTAIPVLLFSGFFVSFDTIPTYLQWMSYISYVRYGFEGVILSIYGLDREDLHCDIDETCHFQK

--------------------------------------------------------------
>63815_63815_2_PDE9A-ABCG1_PDE9A_chr21_44073993_ENST00000328862_ABCG1_chr21_43645781_ENST00000398457_length(transcript)=2916nt_BP=105nt
ACAGTAAAAAGTCCGAGTGCAGCCGCCGGGCGCAGGATGGGATCCGGCTCCTCCAGCTACCGGCCCAAGGCCATCTACCTGGACATCGAT
GGACGCATTCAGAAGAATGCCAGCAGTTACTCTGCAGAGATGACGGAGCCCAAGTCGGTGTGTGTCTCGGTGGATGAGGTGGTGTCCAGC
AACATGGAGGCCACTGAGACGGACCTGCTGAATGGACATCTGAAAAAAGTAGATAATAACCTCACGGAAGCCCAGCGCTTCTCCTCCTTG
CCTCGGAGGGCAGCTGTGAACATTGAATTCAGGGACCTTTCCTATTCGGTTCCTGAAGGACCCTGGTGGAGGAAGAAAGGATACAAGACC
CTCCTGAAAGGAATTTCCGGGAAGTTCAATAGTGGTGAGTTGGTGGCCATTATGGGTCCTTCCGGGGCCGGGAAGTCCACGCTGATGAAC
ATCCTGGCTGGATACAGGGAGACGGGCATGAAGGGGGCCGTCCTCATCAACGGCCTGCCCCGGGACCTGCGCTGCTTCCGGAAGGTGTCC
TGCTACATCATGCAGGATGACATGCTGCTGCCGCATCTCACTGTGCAGGAGGCCATGATGGTGTCGGCACATCTGAAGCTTCAGGAGAAG
GATGAAGGCAGAAGGGAAATGGTCAAGGAGATACTGACAGCGCTGGGCTTGCTGTCTTGCGCCAACACGCGGACCGGGAGCCTGTCAGGT
GGTCAGCGCAAGCGCCTGGCCATCGCGCTGGAGCTGGTGAACAACCCTCCAGTCATGTTCTTCGATGAGCCCACCAGCGGCCTGGACAGC
GCCTCCTGCTTCCAGGTGGTCTCGCTGATGAAAGGGCTCGCTCAAGGGGGTCGCTCCATCATTTGCACCATCCACCAGCCCAGCGCCAAA
CTCTTCGAGCTGTTCGACCAGCTTTACGTCCTGAGTCAAGGACAATGTGTGTACCGGGGAAAAGTCTGCAATCTTGTGCCATATTTGAGG
GATTTGGGTCTGAACTGCCCAACCTACCACAACCCAGCAGATTTTGTCATGGAGGTTGCATCCGGCGAGTACGGTGATCAGAACAGTCGG
CTGGTGAGAGCGGTTCGGGAGGGCATGTGTGACTCAGACCACAAGAGAGACCTCGGGGGTGATGCCGAGGTGAACCCTTTTCTTTGGCAC
CGGCCCTCTGAAGAGGACTCCTCGTCCATGGAAGGCTGCCACAGCTTCTCTGCCAGCTGCCTCACGCAGTTCTGCATCCTCTTCAAGAGG
ACCTTCCTCAGCATCATGAGGGACTCGGTCCTGACACACCTGCGCATCACCTCGCACATTGGGATCGGCCTCCTCATTGGCCTGCTGTAC
TTGGGGATCGGGAACGAAGCCAAGAAGGTCTTGAGCAACTCCGGCTTCCTCTTCTTCTCCATGCTGTTCCTCATGTTCGCGGCCCTCATG
CCTACTGTTCTGACATTTCCCCTGGAGATGGGAGTCTTTCTTCGGGAACACCTGAACTACTGGTACAGCCTGAAGGCCTACTACCTGGCC
AAGACCATGGCAGACGTGCCCTTTCAGATCATGTTCCCAGTGGCCTACTGCAGCATCGTGTACTGGATGACGTCGCAGCCGTCCGACGCC
GTGCGCTTTGTGCTGTTTGCCGCGCTGGGCACCATGACCTCCCTGGTGGCACAGTCCCTGGGCCTGCTGATCGGAGCCGCCTCCACGTCC
CTGCAGGTGGCCACTTTCGTGGGCCCAGTGACAGCCATCCCGGTGCTCCTGTTCTCGGGGTTCTTCGTCAGCTTCGACACCATCCCCACG
TACCTACAGTGGATGTCCTACATCTCCTATGTCAGGTATGGGTTCGAAGGGGTCATCCTCTCCATCTATGGCTTAGACCGGGAAGATCTG
CACTGTGACATCGACGAGACGTGCCACTTCCAGAAGTCGGAGGCCATCCTGCGGGAGCTGGACGTGGAAAATGCCAAGCTGTACCTGGAC
TTCATCGTACTCGGGATTTTCTTCATCTCCCTCCGCCTCATTGCCTATTTTGTCCTCAGGTACAAAATCCGGGCAGAGAGGTAAAACACC
TGAATGCCAGGAAACAGGAAGATTAGACACTGTGGCCGAGGGCACGTCTAGAATCGAGGAGGCAAGCCTGTGCCCGACCGACGACACAGA
GACTCTTCTGATCCAACCCCTAGAACCGCGTTGGGTTTGTGGGTGTCTCGTGCTCAGCCACTCTGCCCAGCTGGGTTGGATCTTCTCTCC
ATTCCCCTTTCTAGCTTTAACTAGGAAGATGTAGGCAGATTGGTGGTTTTTTTTTTTTTAACATACAGAATTTTAAATACCACAACTGGG
GCAGAATTTAAAGCTGCAACACAGCTGGTGATGAGAGGCTTCCTCAGTCCAGTCGCTCCTTAGCACCAGGCACCGTGGGTCCTGGATGGG
GAACTGCAAGCAGCCTCTCAGCTGATGGCTGCACAGTCAGATGTCTGGTGGCAGAGAGTCCGAGCATGGAGCGATTCCATTTTATGACTG
TTGTTTTTCACATTTTCATCTTTCTAAGGTGTGTCTCTTTTCCAATGAGAAGTCATTTTTGCAAGCCAAAAGTCGATCAATCGCATTCAT
TTTAAGAAATTATACCTTTTTAGTACTTGCTGAAGAATGATTCAGGGTAAATCACATACTTTGTTTAGAGAGGCGAGGGGTTTAACCGAG
TCACCCAGCTGGTCTCATACATAGACAGCACTTGTGAAGGATTGAATGCAGGTTCCAGGTGGAGGGAAGACGTGGACACCATCTCCACTG
AGCCATGCAGACATTTTTAAAAGCTATACAAAAAATTGTGAGAAGACATTGGCCAACTCTTTCAAAGTCTTTCTTTTTCCACGTGCTTCT

>63815_63815_2_PDE9A-ABCG1_PDE9A_chr21_44073993_ENST00000328862_ABCG1_chr21_43645781_ENST00000398457_length(amino acids)=675AA_BP=23
MGSGSSSYRPKAIYLDIDGRIQKNASSYSAEMTEPKSVCVSVDEVVSSNMEATETDLLNGHLKKVDNNLTEAQRFSSLPRRAAVNIEFRD
LSYSVPEGPWWRKKGYKTLLKGISGKFNSGELVAIMGPSGAGKSTLMNILAGYRETGMKGAVLINGLPRDLRCFRKVSCYIMQDDMLLPH
LTVQEAMMVSAHLKLQEKDEGRREMVKEILTALGLLSCANTRTGSLSGGQRKRLAIALELVNNPPVMFFDEPTSGLDSASCFQVVSLMKG
LAQGGRSIICTIHQPSAKLFELFDQLYVLSQGQCVYRGKVCNLVPYLRDLGLNCPTYHNPADFVMEVASGEYGDQNSRLVRAVREGMCDS
DHKRDLGGDAEVNPFLWHRPSEEDSSSMEGCHSFSASCLTQFCILFKRTFLSIMRDSVLTHLRITSHIGIGLLIGLLYLGIGNEAKKVLS
NSGFLFFSMLFLMFAALMPTVLTFPLEMGVFLREHLNYWYSLKAYYLAKTMADVPFQIMFPVAYCSIVYWMTSQPSDAVRFVLFAALGTM
TSLVAQSLGLLIGAASTSLQVATFVGPVTAIPVLLFSGFFVSFDTIPTYLQWMSYISYVRYGFEGVILSIYGLDREDLHCDIDETCHFQK

--------------------------------------------------------------
>63815_63815_3_PDE9A-ABCG1_PDE9A_chr21_44073993_ENST00000335440_ABCG1_chr21_43645781_ENST00000398457_length(transcript)=2916nt_BP=105nt
ACAGTAAAAAGTCCGAGTGCAGCCGCCGGGCGCAGGATGGGATCCGGCTCCTCCAGCTACCGGCCCAAGGCCATCTACCTGGACATCGAT
GGACGCATTCAGAAGAATGCCAGCAGTTACTCTGCAGAGATGACGGAGCCCAAGTCGGTGTGTGTCTCGGTGGATGAGGTGGTGTCCAGC
AACATGGAGGCCACTGAGACGGACCTGCTGAATGGACATCTGAAAAAAGTAGATAATAACCTCACGGAAGCCCAGCGCTTCTCCTCCTTG
CCTCGGAGGGCAGCTGTGAACATTGAATTCAGGGACCTTTCCTATTCGGTTCCTGAAGGACCCTGGTGGAGGAAGAAAGGATACAAGACC
CTCCTGAAAGGAATTTCCGGGAAGTTCAATAGTGGTGAGTTGGTGGCCATTATGGGTCCTTCCGGGGCCGGGAAGTCCACGCTGATGAAC
ATCCTGGCTGGATACAGGGAGACGGGCATGAAGGGGGCCGTCCTCATCAACGGCCTGCCCCGGGACCTGCGCTGCTTCCGGAAGGTGTCC
TGCTACATCATGCAGGATGACATGCTGCTGCCGCATCTCACTGTGCAGGAGGCCATGATGGTGTCGGCACATCTGAAGCTTCAGGAGAAG
GATGAAGGCAGAAGGGAAATGGTCAAGGAGATACTGACAGCGCTGGGCTTGCTGTCTTGCGCCAACACGCGGACCGGGAGCCTGTCAGGT
GGTCAGCGCAAGCGCCTGGCCATCGCGCTGGAGCTGGTGAACAACCCTCCAGTCATGTTCTTCGATGAGCCCACCAGCGGCCTGGACAGC
GCCTCCTGCTTCCAGGTGGTCTCGCTGATGAAAGGGCTCGCTCAAGGGGGTCGCTCCATCATTTGCACCATCCACCAGCCCAGCGCCAAA
CTCTTCGAGCTGTTCGACCAGCTTTACGTCCTGAGTCAAGGACAATGTGTGTACCGGGGAAAAGTCTGCAATCTTGTGCCATATTTGAGG
GATTTGGGTCTGAACTGCCCAACCTACCACAACCCAGCAGATTTTGTCATGGAGGTTGCATCCGGCGAGTACGGTGATCAGAACAGTCGG
CTGGTGAGAGCGGTTCGGGAGGGCATGTGTGACTCAGACCACAAGAGAGACCTCGGGGGTGATGCCGAGGTGAACCCTTTTCTTTGGCAC
CGGCCCTCTGAAGAGGACTCCTCGTCCATGGAAGGCTGCCACAGCTTCTCTGCCAGCTGCCTCACGCAGTTCTGCATCCTCTTCAAGAGG
ACCTTCCTCAGCATCATGAGGGACTCGGTCCTGACACACCTGCGCATCACCTCGCACATTGGGATCGGCCTCCTCATTGGCCTGCTGTAC
TTGGGGATCGGGAACGAAGCCAAGAAGGTCTTGAGCAACTCCGGCTTCCTCTTCTTCTCCATGCTGTTCCTCATGTTCGCGGCCCTCATG
CCTACTGTTCTGACATTTCCCCTGGAGATGGGAGTCTTTCTTCGGGAACACCTGAACTACTGGTACAGCCTGAAGGCCTACTACCTGGCC
AAGACCATGGCAGACGTGCCCTTTCAGATCATGTTCCCAGTGGCCTACTGCAGCATCGTGTACTGGATGACGTCGCAGCCGTCCGACGCC
GTGCGCTTTGTGCTGTTTGCCGCGCTGGGCACCATGACCTCCCTGGTGGCACAGTCCCTGGGCCTGCTGATCGGAGCCGCCTCCACGTCC
CTGCAGGTGGCCACTTTCGTGGGCCCAGTGACAGCCATCCCGGTGCTCCTGTTCTCGGGGTTCTTCGTCAGCTTCGACACCATCCCCACG
TACCTACAGTGGATGTCCTACATCTCCTATGTCAGGTATGGGTTCGAAGGGGTCATCCTCTCCATCTATGGCTTAGACCGGGAAGATCTG
CACTGTGACATCGACGAGACGTGCCACTTCCAGAAGTCGGAGGCCATCCTGCGGGAGCTGGACGTGGAAAATGCCAAGCTGTACCTGGAC
TTCATCGTACTCGGGATTTTCTTCATCTCCCTCCGCCTCATTGCCTATTTTGTCCTCAGGTACAAAATCCGGGCAGAGAGGTAAAACACC
TGAATGCCAGGAAACAGGAAGATTAGACACTGTGGCCGAGGGCACGTCTAGAATCGAGGAGGCAAGCCTGTGCCCGACCGACGACACAGA
GACTCTTCTGATCCAACCCCTAGAACCGCGTTGGGTTTGTGGGTGTCTCGTGCTCAGCCACTCTGCCCAGCTGGGTTGGATCTTCTCTCC
ATTCCCCTTTCTAGCTTTAACTAGGAAGATGTAGGCAGATTGGTGGTTTTTTTTTTTTTAACATACAGAATTTTAAATACCACAACTGGG
GCAGAATTTAAAGCTGCAACACAGCTGGTGATGAGAGGCTTCCTCAGTCCAGTCGCTCCTTAGCACCAGGCACCGTGGGTCCTGGATGGG
GAACTGCAAGCAGCCTCTCAGCTGATGGCTGCACAGTCAGATGTCTGGTGGCAGAGAGTCCGAGCATGGAGCGATTCCATTTTATGACTG
TTGTTTTTCACATTTTCATCTTTCTAAGGTGTGTCTCTTTTCCAATGAGAAGTCATTTTTGCAAGCCAAAAGTCGATCAATCGCATTCAT
TTTAAGAAATTATACCTTTTTAGTACTTGCTGAAGAATGATTCAGGGTAAATCACATACTTTGTTTAGAGAGGCGAGGGGTTTAACCGAG
TCACCCAGCTGGTCTCATACATAGACAGCACTTGTGAAGGATTGAATGCAGGTTCCAGGTGGAGGGAAGACGTGGACACCATCTCCACTG
AGCCATGCAGACATTTTTAAAAGCTATACAAAAAATTGTGAGAAGACATTGGCCAACTCTTTCAAAGTCTTTCTTTTTCCACGTGCTTCT

>63815_63815_3_PDE9A-ABCG1_PDE9A_chr21_44073993_ENST00000335440_ABCG1_chr21_43645781_ENST00000398457_length(amino acids)=675AA_BP=23
MGSGSSSYRPKAIYLDIDGRIQKNASSYSAEMTEPKSVCVSVDEVVSSNMEATETDLLNGHLKKVDNNLTEAQRFSSLPRRAAVNIEFRD
LSYSVPEGPWWRKKGYKTLLKGISGKFNSGELVAIMGPSGAGKSTLMNILAGYRETGMKGAVLINGLPRDLRCFRKVSCYIMQDDMLLPH
LTVQEAMMVSAHLKLQEKDEGRREMVKEILTALGLLSCANTRTGSLSGGQRKRLAIALELVNNPPVMFFDEPTSGLDSASCFQVVSLMKG
LAQGGRSIICTIHQPSAKLFELFDQLYVLSQGQCVYRGKVCNLVPYLRDLGLNCPTYHNPADFVMEVASGEYGDQNSRLVRAVREGMCDS
DHKRDLGGDAEVNPFLWHRPSEEDSSSMEGCHSFSASCLTQFCILFKRTFLSIMRDSVLTHLRITSHIGIGLLIGLLYLGIGNEAKKVLS
NSGFLFFSMLFLMFAALMPTVLTFPLEMGVFLREHLNYWYSLKAYYLAKTMADVPFQIMFPVAYCSIVYWMTSQPSDAVRFVLFAALGTM
TSLVAQSLGLLIGAASTSLQVATFVGPVTAIPVLLFSGFFVSFDTIPTYLQWMSYISYVRYGFEGVILSIYGLDREDLHCDIDETCHFQK

--------------------------------------------------------------
>63815_63815_4_PDE9A-ABCG1_PDE9A_chr21_44073993_ENST00000335512_ABCG1_chr21_43645781_ENST00000398457_length(transcript)=2945nt_BP=134nt
CCTCCCGCGGCGGCTGGCGTCGGGAAAGTACAGTAAAAAGTCCGAGTGCAGCCGCCGGGCGCAGGATGGGATCCGGCTCCTCCAGCTACC
GGCCCAAGGCCATCTACCTGGACATCGATGGACGCATTCAGAAGAATGCCAGCAGTTACTCTGCAGAGATGACGGAGCCCAAGTCGGTGT
GTGTCTCGGTGGATGAGGTGGTGTCCAGCAACATGGAGGCCACTGAGACGGACCTGCTGAATGGACATCTGAAAAAAGTAGATAATAACC
TCACGGAAGCCCAGCGCTTCTCCTCCTTGCCTCGGAGGGCAGCTGTGAACATTGAATTCAGGGACCTTTCCTATTCGGTTCCTGAAGGAC
CCTGGTGGAGGAAGAAAGGATACAAGACCCTCCTGAAAGGAATTTCCGGGAAGTTCAATAGTGGTGAGTTGGTGGCCATTATGGGTCCTT
CCGGGGCCGGGAAGTCCACGCTGATGAACATCCTGGCTGGATACAGGGAGACGGGCATGAAGGGGGCCGTCCTCATCAACGGCCTGCCCC
GGGACCTGCGCTGCTTCCGGAAGGTGTCCTGCTACATCATGCAGGATGACATGCTGCTGCCGCATCTCACTGTGCAGGAGGCCATGATGG
TGTCGGCACATCTGAAGCTTCAGGAGAAGGATGAAGGCAGAAGGGAAATGGTCAAGGAGATACTGACAGCGCTGGGCTTGCTGTCTTGCG
CCAACACGCGGACCGGGAGCCTGTCAGGTGGTCAGCGCAAGCGCCTGGCCATCGCGCTGGAGCTGGTGAACAACCCTCCAGTCATGTTCT
TCGATGAGCCCACCAGCGGCCTGGACAGCGCCTCCTGCTTCCAGGTGGTCTCGCTGATGAAAGGGCTCGCTCAAGGGGGTCGCTCCATCA
TTTGCACCATCCACCAGCCCAGCGCCAAACTCTTCGAGCTGTTCGACCAGCTTTACGTCCTGAGTCAAGGACAATGTGTGTACCGGGGAA
AAGTCTGCAATCTTGTGCCATATTTGAGGGATTTGGGTCTGAACTGCCCAACCTACCACAACCCAGCAGATTTTGTCATGGAGGTTGCAT
CCGGCGAGTACGGTGATCAGAACAGTCGGCTGGTGAGAGCGGTTCGGGAGGGCATGTGTGACTCAGACCACAAGAGAGACCTCGGGGGTG
ATGCCGAGGTGAACCCTTTTCTTTGGCACCGGCCCTCTGAAGAGGACTCCTCGTCCATGGAAGGCTGCCACAGCTTCTCTGCCAGCTGCC
TCACGCAGTTCTGCATCCTCTTCAAGAGGACCTTCCTCAGCATCATGAGGGACTCGGTCCTGACACACCTGCGCATCACCTCGCACATTG
GGATCGGCCTCCTCATTGGCCTGCTGTACTTGGGGATCGGGAACGAAGCCAAGAAGGTCTTGAGCAACTCCGGCTTCCTCTTCTTCTCCA
TGCTGTTCCTCATGTTCGCGGCCCTCATGCCTACTGTTCTGACATTTCCCCTGGAGATGGGAGTCTTTCTTCGGGAACACCTGAACTACT
GGTACAGCCTGAAGGCCTACTACCTGGCCAAGACCATGGCAGACGTGCCCTTTCAGATCATGTTCCCAGTGGCCTACTGCAGCATCGTGT
ACTGGATGACGTCGCAGCCGTCCGACGCCGTGCGCTTTGTGCTGTTTGCCGCGCTGGGCACCATGACCTCCCTGGTGGCACAGTCCCTGG
GCCTGCTGATCGGAGCCGCCTCCACGTCCCTGCAGGTGGCCACTTTCGTGGGCCCAGTGACAGCCATCCCGGTGCTCCTGTTCTCGGGGT
TCTTCGTCAGCTTCGACACCATCCCCACGTACCTACAGTGGATGTCCTACATCTCCTATGTCAGGTATGGGTTCGAAGGGGTCATCCTCT
CCATCTATGGCTTAGACCGGGAAGATCTGCACTGTGACATCGACGAGACGTGCCACTTCCAGAAGTCGGAGGCCATCCTGCGGGAGCTGG
ACGTGGAAAATGCCAAGCTGTACCTGGACTTCATCGTACTCGGGATTTTCTTCATCTCCCTCCGCCTCATTGCCTATTTTGTCCTCAGGT
ACAAAATCCGGGCAGAGAGGTAAAACACCTGAATGCCAGGAAACAGGAAGATTAGACACTGTGGCCGAGGGCACGTCTAGAATCGAGGAG
GCAAGCCTGTGCCCGACCGACGACACAGAGACTCTTCTGATCCAACCCCTAGAACCGCGTTGGGTTTGTGGGTGTCTCGTGCTCAGCCAC
TCTGCCCAGCTGGGTTGGATCTTCTCTCCATTCCCCTTTCTAGCTTTAACTAGGAAGATGTAGGCAGATTGGTGGTTTTTTTTTTTTTAA
CATACAGAATTTTAAATACCACAACTGGGGCAGAATTTAAAGCTGCAACACAGCTGGTGATGAGAGGCTTCCTCAGTCCAGTCGCTCCTT
AGCACCAGGCACCGTGGGTCCTGGATGGGGAACTGCAAGCAGCCTCTCAGCTGATGGCTGCACAGTCAGATGTCTGGTGGCAGAGAGTCC
GAGCATGGAGCGATTCCATTTTATGACTGTTGTTTTTCACATTTTCATCTTTCTAAGGTGTGTCTCTTTTCCAATGAGAAGTCATTTTTG
CAAGCCAAAAGTCGATCAATCGCATTCATTTTAAGAAATTATACCTTTTTAGTACTTGCTGAAGAATGATTCAGGGTAAATCACATACTT
TGTTTAGAGAGGCGAGGGGTTTAACCGAGTCACCCAGCTGGTCTCATACATAGACAGCACTTGTGAAGGATTGAATGCAGGTTCCAGGTG
GAGGGAAGACGTGGACACCATCTCCACTGAGCCATGCAGACATTTTTAAAAGCTATACAAAAAATTGTGAGAAGACATTGGCCAACTCTT

>63815_63815_4_PDE9A-ABCG1_PDE9A_chr21_44073993_ENST00000335512_ABCG1_chr21_43645781_ENST00000398457_length(amino acids)=675AA_BP=23
MGSGSSSYRPKAIYLDIDGRIQKNASSYSAEMTEPKSVCVSVDEVVSSNMEATETDLLNGHLKKVDNNLTEAQRFSSLPRRAAVNIEFRD
LSYSVPEGPWWRKKGYKTLLKGISGKFNSGELVAIMGPSGAGKSTLMNILAGYRETGMKGAVLINGLPRDLRCFRKVSCYIMQDDMLLPH
LTVQEAMMVSAHLKLQEKDEGRREMVKEILTALGLLSCANTRTGSLSGGQRKRLAIALELVNNPPVMFFDEPTSGLDSASCFQVVSLMKG
LAQGGRSIICTIHQPSAKLFELFDQLYVLSQGQCVYRGKVCNLVPYLRDLGLNCPTYHNPADFVMEVASGEYGDQNSRLVRAVREGMCDS
DHKRDLGGDAEVNPFLWHRPSEEDSSSMEGCHSFSASCLTQFCILFKRTFLSIMRDSVLTHLRITSHIGIGLLIGLLYLGIGNEAKKVLS
NSGFLFFSMLFLMFAALMPTVLTFPLEMGVFLREHLNYWYSLKAYYLAKTMADVPFQIMFPVAYCSIVYWMTSQPSDAVRFVLFAALGTM
TSLVAQSLGLLIGAASTSLQVATFVGPVTAIPVLLFSGFFVSFDTIPTYLQWMSYISYVRYGFEGVILSIYGLDREDLHCDIDETCHFQK

--------------------------------------------------------------
>63815_63815_5_PDE9A-ABCG1_PDE9A_chr21_44073993_ENST00000349112_ABCG1_chr21_43645781_ENST00000398457_length(transcript)=2882nt_BP=71nt
GGATGGGATCCGGCTCCTCCAGCTACCGGCCCAAGGCCATCTACCTGGACATCGATGGACGCATTCAGAAGAATGCCAGCAGTTACTCTG
CAGAGATGACGGAGCCCAAGTCGGTGTGTGTCTCGGTGGATGAGGTGGTGTCCAGCAACATGGAGGCCACTGAGACGGACCTGCTGAATG
GACATCTGAAAAAAGTAGATAATAACCTCACGGAAGCCCAGCGCTTCTCCTCCTTGCCTCGGAGGGCAGCTGTGAACATTGAATTCAGGG
ACCTTTCCTATTCGGTTCCTGAAGGACCCTGGTGGAGGAAGAAAGGATACAAGACCCTCCTGAAAGGAATTTCCGGGAAGTTCAATAGTG
GTGAGTTGGTGGCCATTATGGGTCCTTCCGGGGCCGGGAAGTCCACGCTGATGAACATCCTGGCTGGATACAGGGAGACGGGCATGAAGG
GGGCCGTCCTCATCAACGGCCTGCCCCGGGACCTGCGCTGCTTCCGGAAGGTGTCCTGCTACATCATGCAGGATGACATGCTGCTGCCGC
ATCTCACTGTGCAGGAGGCCATGATGGTGTCGGCACATCTGAAGCTTCAGGAGAAGGATGAAGGCAGAAGGGAAATGGTCAAGGAGATAC
TGACAGCGCTGGGCTTGCTGTCTTGCGCCAACACGCGGACCGGGAGCCTGTCAGGTGGTCAGCGCAAGCGCCTGGCCATCGCGCTGGAGC
TGGTGAACAACCCTCCAGTCATGTTCTTCGATGAGCCCACCAGCGGCCTGGACAGCGCCTCCTGCTTCCAGGTGGTCTCGCTGATGAAAG
GGCTCGCTCAAGGGGGTCGCTCCATCATTTGCACCATCCACCAGCCCAGCGCCAAACTCTTCGAGCTGTTCGACCAGCTTTACGTCCTGA
GTCAAGGACAATGTGTGTACCGGGGAAAAGTCTGCAATCTTGTGCCATATTTGAGGGATTTGGGTCTGAACTGCCCAACCTACCACAACC
CAGCAGATTTTGTCATGGAGGTTGCATCCGGCGAGTACGGTGATCAGAACAGTCGGCTGGTGAGAGCGGTTCGGGAGGGCATGTGTGACT
CAGACCACAAGAGAGACCTCGGGGGTGATGCCGAGGTGAACCCTTTTCTTTGGCACCGGCCCTCTGAAGAGGACTCCTCGTCCATGGAAG
GCTGCCACAGCTTCTCTGCCAGCTGCCTCACGCAGTTCTGCATCCTCTTCAAGAGGACCTTCCTCAGCATCATGAGGGACTCGGTCCTGA
CACACCTGCGCATCACCTCGCACATTGGGATCGGCCTCCTCATTGGCCTGCTGTACTTGGGGATCGGGAACGAAGCCAAGAAGGTCTTGA
GCAACTCCGGCTTCCTCTTCTTCTCCATGCTGTTCCTCATGTTCGCGGCCCTCATGCCTACTGTTCTGACATTTCCCCTGGAGATGGGAG
TCTTTCTTCGGGAACACCTGAACTACTGGTACAGCCTGAAGGCCTACTACCTGGCCAAGACCATGGCAGACGTGCCCTTTCAGATCATGT
TCCCAGTGGCCTACTGCAGCATCGTGTACTGGATGACGTCGCAGCCGTCCGACGCCGTGCGCTTTGTGCTGTTTGCCGCGCTGGGCACCA
TGACCTCCCTGGTGGCACAGTCCCTGGGCCTGCTGATCGGAGCCGCCTCCACGTCCCTGCAGGTGGCCACTTTCGTGGGCCCAGTGACAG
CCATCCCGGTGCTCCTGTTCTCGGGGTTCTTCGTCAGCTTCGACACCATCCCCACGTACCTACAGTGGATGTCCTACATCTCCTATGTCA
GGTATGGGTTCGAAGGGGTCATCCTCTCCATCTATGGCTTAGACCGGGAAGATCTGCACTGTGACATCGACGAGACGTGCCACTTCCAGA
AGTCGGAGGCCATCCTGCGGGAGCTGGACGTGGAAAATGCCAAGCTGTACCTGGACTTCATCGTACTCGGGATTTTCTTCATCTCCCTCC
GCCTCATTGCCTATTTTGTCCTCAGGTACAAAATCCGGGCAGAGAGGTAAAACACCTGAATGCCAGGAAACAGGAAGATTAGACACTGTG
GCCGAGGGCACGTCTAGAATCGAGGAGGCAAGCCTGTGCCCGACCGACGACACAGAGACTCTTCTGATCCAACCCCTAGAACCGCGTTGG
GTTTGTGGGTGTCTCGTGCTCAGCCACTCTGCCCAGCTGGGTTGGATCTTCTCTCCATTCCCCTTTCTAGCTTTAACTAGGAAGATGTAG
GCAGATTGGTGGTTTTTTTTTTTTTAACATACAGAATTTTAAATACCACAACTGGGGCAGAATTTAAAGCTGCAACACAGCTGGTGATGA
GAGGCTTCCTCAGTCCAGTCGCTCCTTAGCACCAGGCACCGTGGGTCCTGGATGGGGAACTGCAAGCAGCCTCTCAGCTGATGGCTGCAC
AGTCAGATGTCTGGTGGCAGAGAGTCCGAGCATGGAGCGATTCCATTTTATGACTGTTGTTTTTCACATTTTCATCTTTCTAAGGTGTGT
CTCTTTTCCAATGAGAAGTCATTTTTGCAAGCCAAAAGTCGATCAATCGCATTCATTTTAAGAAATTATACCTTTTTAGTACTTGCTGAA
GAATGATTCAGGGTAAATCACATACTTTGTTTAGAGAGGCGAGGGGTTTAACCGAGTCACCCAGCTGGTCTCATACATAGACAGCACTTG
TGAAGGATTGAATGCAGGTTCCAGGTGGAGGGAAGACGTGGACACCATCTCCACTGAGCCATGCAGACATTTTTAAAAGCTATACAAAAA
ATTGTGAGAAGACATTGGCCAACTCTTTCAAAGTCTTTCTTTTTCCACGTGCTTCTTATTTTAAGCGAAATATATTGTTTGTTTCTTCCT

>63815_63815_5_PDE9A-ABCG1_PDE9A_chr21_44073993_ENST00000349112_ABCG1_chr21_43645781_ENST00000398457_length(amino acids)=675AA_BP=23
MGSGSSSYRPKAIYLDIDGRIQKNASSYSAEMTEPKSVCVSVDEVVSSNMEATETDLLNGHLKKVDNNLTEAQRFSSLPRRAAVNIEFRD
LSYSVPEGPWWRKKGYKTLLKGISGKFNSGELVAIMGPSGAGKSTLMNILAGYRETGMKGAVLINGLPRDLRCFRKVSCYIMQDDMLLPH
LTVQEAMMVSAHLKLQEKDEGRREMVKEILTALGLLSCANTRTGSLSGGQRKRLAIALELVNNPPVMFFDEPTSGLDSASCFQVVSLMKG
LAQGGRSIICTIHQPSAKLFELFDQLYVLSQGQCVYRGKVCNLVPYLRDLGLNCPTYHNPADFVMEVASGEYGDQNSRLVRAVREGMCDS
DHKRDLGGDAEVNPFLWHRPSEEDSSSMEGCHSFSASCLTQFCILFKRTFLSIMRDSVLTHLRITSHIGIGLLIGLLYLGIGNEAKKVLS
NSGFLFFSMLFLMFAALMPTVLTFPLEMGVFLREHLNYWYSLKAYYLAKTMADVPFQIMFPVAYCSIVYWMTSQPSDAVRFVLFAALGTM
TSLVAQSLGLLIGAASTSLQVATFVGPVTAIPVLLFSGFFVSFDTIPTYLQWMSYISYVRYGFEGVILSIYGLDREDLHCDIDETCHFQK

--------------------------------------------------------------
>63815_63815_6_PDE9A-ABCG1_PDE9A_chr21_44073993_ENST00000380328_ABCG1_chr21_43645781_ENST00000398457_length(transcript)=2916nt_BP=105nt
ACAGTAAAAAGTCCGAGTGCAGCCGCCGGGCGCAGGATGGGATCCGGCTCCTCCAGCTACCGGCCCAAGGCCATCTACCTGGACATCGAT
GGACGCATTCAGAAGAATGCCAGCAGTTACTCTGCAGAGATGACGGAGCCCAAGTCGGTGTGTGTCTCGGTGGATGAGGTGGTGTCCAGC
AACATGGAGGCCACTGAGACGGACCTGCTGAATGGACATCTGAAAAAAGTAGATAATAACCTCACGGAAGCCCAGCGCTTCTCCTCCTTG
CCTCGGAGGGCAGCTGTGAACATTGAATTCAGGGACCTTTCCTATTCGGTTCCTGAAGGACCCTGGTGGAGGAAGAAAGGATACAAGACC
CTCCTGAAAGGAATTTCCGGGAAGTTCAATAGTGGTGAGTTGGTGGCCATTATGGGTCCTTCCGGGGCCGGGAAGTCCACGCTGATGAAC
ATCCTGGCTGGATACAGGGAGACGGGCATGAAGGGGGCCGTCCTCATCAACGGCCTGCCCCGGGACCTGCGCTGCTTCCGGAAGGTGTCC
TGCTACATCATGCAGGATGACATGCTGCTGCCGCATCTCACTGTGCAGGAGGCCATGATGGTGTCGGCACATCTGAAGCTTCAGGAGAAG
GATGAAGGCAGAAGGGAAATGGTCAAGGAGATACTGACAGCGCTGGGCTTGCTGTCTTGCGCCAACACGCGGACCGGGAGCCTGTCAGGT
GGTCAGCGCAAGCGCCTGGCCATCGCGCTGGAGCTGGTGAACAACCCTCCAGTCATGTTCTTCGATGAGCCCACCAGCGGCCTGGACAGC
GCCTCCTGCTTCCAGGTGGTCTCGCTGATGAAAGGGCTCGCTCAAGGGGGTCGCTCCATCATTTGCACCATCCACCAGCCCAGCGCCAAA
CTCTTCGAGCTGTTCGACCAGCTTTACGTCCTGAGTCAAGGACAATGTGTGTACCGGGGAAAAGTCTGCAATCTTGTGCCATATTTGAGG
GATTTGGGTCTGAACTGCCCAACCTACCACAACCCAGCAGATTTTGTCATGGAGGTTGCATCCGGCGAGTACGGTGATCAGAACAGTCGG
CTGGTGAGAGCGGTTCGGGAGGGCATGTGTGACTCAGACCACAAGAGAGACCTCGGGGGTGATGCCGAGGTGAACCCTTTTCTTTGGCAC
CGGCCCTCTGAAGAGGACTCCTCGTCCATGGAAGGCTGCCACAGCTTCTCTGCCAGCTGCCTCACGCAGTTCTGCATCCTCTTCAAGAGG
ACCTTCCTCAGCATCATGAGGGACTCGGTCCTGACACACCTGCGCATCACCTCGCACATTGGGATCGGCCTCCTCATTGGCCTGCTGTAC
TTGGGGATCGGGAACGAAGCCAAGAAGGTCTTGAGCAACTCCGGCTTCCTCTTCTTCTCCATGCTGTTCCTCATGTTCGCGGCCCTCATG
CCTACTGTTCTGACATTTCCCCTGGAGATGGGAGTCTTTCTTCGGGAACACCTGAACTACTGGTACAGCCTGAAGGCCTACTACCTGGCC
AAGACCATGGCAGACGTGCCCTTTCAGATCATGTTCCCAGTGGCCTACTGCAGCATCGTGTACTGGATGACGTCGCAGCCGTCCGACGCC
GTGCGCTTTGTGCTGTTTGCCGCGCTGGGCACCATGACCTCCCTGGTGGCACAGTCCCTGGGCCTGCTGATCGGAGCCGCCTCCACGTCC
CTGCAGGTGGCCACTTTCGTGGGCCCAGTGACAGCCATCCCGGTGCTCCTGTTCTCGGGGTTCTTCGTCAGCTTCGACACCATCCCCACG
TACCTACAGTGGATGTCCTACATCTCCTATGTCAGGTATGGGTTCGAAGGGGTCATCCTCTCCATCTATGGCTTAGACCGGGAAGATCTG
CACTGTGACATCGACGAGACGTGCCACTTCCAGAAGTCGGAGGCCATCCTGCGGGAGCTGGACGTGGAAAATGCCAAGCTGTACCTGGAC
TTCATCGTACTCGGGATTTTCTTCATCTCCCTCCGCCTCATTGCCTATTTTGTCCTCAGGTACAAAATCCGGGCAGAGAGGTAAAACACC
TGAATGCCAGGAAACAGGAAGATTAGACACTGTGGCCGAGGGCACGTCTAGAATCGAGGAGGCAAGCCTGTGCCCGACCGACGACACAGA
GACTCTTCTGATCCAACCCCTAGAACCGCGTTGGGTTTGTGGGTGTCTCGTGCTCAGCCACTCTGCCCAGCTGGGTTGGATCTTCTCTCC
ATTCCCCTTTCTAGCTTTAACTAGGAAGATGTAGGCAGATTGGTGGTTTTTTTTTTTTTAACATACAGAATTTTAAATACCACAACTGGG
GCAGAATTTAAAGCTGCAACACAGCTGGTGATGAGAGGCTTCCTCAGTCCAGTCGCTCCTTAGCACCAGGCACCGTGGGTCCTGGATGGG
GAACTGCAAGCAGCCTCTCAGCTGATGGCTGCACAGTCAGATGTCTGGTGGCAGAGAGTCCGAGCATGGAGCGATTCCATTTTATGACTG
TTGTTTTTCACATTTTCATCTTTCTAAGGTGTGTCTCTTTTCCAATGAGAAGTCATTTTTGCAAGCCAAAAGTCGATCAATCGCATTCAT
TTTAAGAAATTATACCTTTTTAGTACTTGCTGAAGAATGATTCAGGGTAAATCACATACTTTGTTTAGAGAGGCGAGGGGTTTAACCGAG
TCACCCAGCTGGTCTCATACATAGACAGCACTTGTGAAGGATTGAATGCAGGTTCCAGGTGGAGGGAAGACGTGGACACCATCTCCACTG
AGCCATGCAGACATTTTTAAAAGCTATACAAAAAATTGTGAGAAGACATTGGCCAACTCTTTCAAAGTCTTTCTTTTTCCACGTGCTTCT

>63815_63815_6_PDE9A-ABCG1_PDE9A_chr21_44073993_ENST00000380328_ABCG1_chr21_43645781_ENST00000398457_length(amino acids)=675AA_BP=23
MGSGSSSYRPKAIYLDIDGRIQKNASSYSAEMTEPKSVCVSVDEVVSSNMEATETDLLNGHLKKVDNNLTEAQRFSSLPRRAAVNIEFRD
LSYSVPEGPWWRKKGYKTLLKGISGKFNSGELVAIMGPSGAGKSTLMNILAGYRETGMKGAVLINGLPRDLRCFRKVSCYIMQDDMLLPH
LTVQEAMMVSAHLKLQEKDEGRREMVKEILTALGLLSCANTRTGSLSGGQRKRLAIALELVNNPPVMFFDEPTSGLDSASCFQVVSLMKG
LAQGGRSIICTIHQPSAKLFELFDQLYVLSQGQCVYRGKVCNLVPYLRDLGLNCPTYHNPADFVMEVASGEYGDQNSRLVRAVREGMCDS
DHKRDLGGDAEVNPFLWHRPSEEDSSSMEGCHSFSASCLTQFCILFKRTFLSIMRDSVLTHLRITSHIGIGLLIGLLYLGIGNEAKKVLS
NSGFLFFSMLFLMFAALMPTVLTFPLEMGVFLREHLNYWYSLKAYYLAKTMADVPFQIMFPVAYCSIVYWMTSQPSDAVRFVLFAALGTM
TSLVAQSLGLLIGAASTSLQVATFVGPVTAIPVLLFSGFFVSFDTIPTYLQWMSYISYVRYGFEGVILSIYGLDREDLHCDIDETCHFQK

--------------------------------------------------------------
>63815_63815_7_PDE9A-ABCG1_PDE9A_chr21_44073993_ENST00000398236_ABCG1_chr21_43645781_ENST00000398457_length(transcript)=2916nt_BP=105nt
ACAGTAAAAAGTCCGAGTGCAGCCGCCGGGCGCAGGATGGGATCCGGCTCCTCCAGCTACCGGCCCAAGGCCATCTACCTGGACATCGAT
GGACGCATTCAGAAGAATGCCAGCAGTTACTCTGCAGAGATGACGGAGCCCAAGTCGGTGTGTGTCTCGGTGGATGAGGTGGTGTCCAGC
AACATGGAGGCCACTGAGACGGACCTGCTGAATGGACATCTGAAAAAAGTAGATAATAACCTCACGGAAGCCCAGCGCTTCTCCTCCTTG
CCTCGGAGGGCAGCTGTGAACATTGAATTCAGGGACCTTTCCTATTCGGTTCCTGAAGGACCCTGGTGGAGGAAGAAAGGATACAAGACC
CTCCTGAAAGGAATTTCCGGGAAGTTCAATAGTGGTGAGTTGGTGGCCATTATGGGTCCTTCCGGGGCCGGGAAGTCCACGCTGATGAAC
ATCCTGGCTGGATACAGGGAGACGGGCATGAAGGGGGCCGTCCTCATCAACGGCCTGCCCCGGGACCTGCGCTGCTTCCGGAAGGTGTCC
TGCTACATCATGCAGGATGACATGCTGCTGCCGCATCTCACTGTGCAGGAGGCCATGATGGTGTCGGCACATCTGAAGCTTCAGGAGAAG
GATGAAGGCAGAAGGGAAATGGTCAAGGAGATACTGACAGCGCTGGGCTTGCTGTCTTGCGCCAACACGCGGACCGGGAGCCTGTCAGGT
GGTCAGCGCAAGCGCCTGGCCATCGCGCTGGAGCTGGTGAACAACCCTCCAGTCATGTTCTTCGATGAGCCCACCAGCGGCCTGGACAGC
GCCTCCTGCTTCCAGGTGGTCTCGCTGATGAAAGGGCTCGCTCAAGGGGGTCGCTCCATCATTTGCACCATCCACCAGCCCAGCGCCAAA
CTCTTCGAGCTGTTCGACCAGCTTTACGTCCTGAGTCAAGGACAATGTGTGTACCGGGGAAAAGTCTGCAATCTTGTGCCATATTTGAGG
GATTTGGGTCTGAACTGCCCAACCTACCACAACCCAGCAGATTTTGTCATGGAGGTTGCATCCGGCGAGTACGGTGATCAGAACAGTCGG
CTGGTGAGAGCGGTTCGGGAGGGCATGTGTGACTCAGACCACAAGAGAGACCTCGGGGGTGATGCCGAGGTGAACCCTTTTCTTTGGCAC
CGGCCCTCTGAAGAGGACTCCTCGTCCATGGAAGGCTGCCACAGCTTCTCTGCCAGCTGCCTCACGCAGTTCTGCATCCTCTTCAAGAGG
ACCTTCCTCAGCATCATGAGGGACTCGGTCCTGACACACCTGCGCATCACCTCGCACATTGGGATCGGCCTCCTCATTGGCCTGCTGTAC
TTGGGGATCGGGAACGAAGCCAAGAAGGTCTTGAGCAACTCCGGCTTCCTCTTCTTCTCCATGCTGTTCCTCATGTTCGCGGCCCTCATG
CCTACTGTTCTGACATTTCCCCTGGAGATGGGAGTCTTTCTTCGGGAACACCTGAACTACTGGTACAGCCTGAAGGCCTACTACCTGGCC
AAGACCATGGCAGACGTGCCCTTTCAGATCATGTTCCCAGTGGCCTACTGCAGCATCGTGTACTGGATGACGTCGCAGCCGTCCGACGCC
GTGCGCTTTGTGCTGTTTGCCGCGCTGGGCACCATGACCTCCCTGGTGGCACAGTCCCTGGGCCTGCTGATCGGAGCCGCCTCCACGTCC
CTGCAGGTGGCCACTTTCGTGGGCCCAGTGACAGCCATCCCGGTGCTCCTGTTCTCGGGGTTCTTCGTCAGCTTCGACACCATCCCCACG
TACCTACAGTGGATGTCCTACATCTCCTATGTCAGGTATGGGTTCGAAGGGGTCATCCTCTCCATCTATGGCTTAGACCGGGAAGATCTG
CACTGTGACATCGACGAGACGTGCCACTTCCAGAAGTCGGAGGCCATCCTGCGGGAGCTGGACGTGGAAAATGCCAAGCTGTACCTGGAC
TTCATCGTACTCGGGATTTTCTTCATCTCCCTCCGCCTCATTGCCTATTTTGTCCTCAGGTACAAAATCCGGGCAGAGAGGTAAAACACC
TGAATGCCAGGAAACAGGAAGATTAGACACTGTGGCCGAGGGCACGTCTAGAATCGAGGAGGCAAGCCTGTGCCCGACCGACGACACAGA
GACTCTTCTGATCCAACCCCTAGAACCGCGTTGGGTTTGTGGGTGTCTCGTGCTCAGCCACTCTGCCCAGCTGGGTTGGATCTTCTCTCC
ATTCCCCTTTCTAGCTTTAACTAGGAAGATGTAGGCAGATTGGTGGTTTTTTTTTTTTTAACATACAGAATTTTAAATACCACAACTGGG
GCAGAATTTAAAGCTGCAACACAGCTGGTGATGAGAGGCTTCCTCAGTCCAGTCGCTCCTTAGCACCAGGCACCGTGGGTCCTGGATGGG
GAACTGCAAGCAGCCTCTCAGCTGATGGCTGCACAGTCAGATGTCTGGTGGCAGAGAGTCCGAGCATGGAGCGATTCCATTTTATGACTG
TTGTTTTTCACATTTTCATCTTTCTAAGGTGTGTCTCTTTTCCAATGAGAAGTCATTTTTGCAAGCCAAAAGTCGATCAATCGCATTCAT
TTTAAGAAATTATACCTTTTTAGTACTTGCTGAAGAATGATTCAGGGTAAATCACATACTTTGTTTAGAGAGGCGAGGGGTTTAACCGAG
TCACCCAGCTGGTCTCATACATAGACAGCACTTGTGAAGGATTGAATGCAGGTTCCAGGTGGAGGGAAGACGTGGACACCATCTCCACTG
AGCCATGCAGACATTTTTAAAAGCTATACAAAAAATTGTGAGAAGACATTGGCCAACTCTTTCAAAGTCTTTCTTTTTCCACGTGCTTCT

>63815_63815_7_PDE9A-ABCG1_PDE9A_chr21_44073993_ENST00000398236_ABCG1_chr21_43645781_ENST00000398457_length(amino acids)=675AA_BP=23
MGSGSSSYRPKAIYLDIDGRIQKNASSYSAEMTEPKSVCVSVDEVVSSNMEATETDLLNGHLKKVDNNLTEAQRFSSLPRRAAVNIEFRD
LSYSVPEGPWWRKKGYKTLLKGISGKFNSGELVAIMGPSGAGKSTLMNILAGYRETGMKGAVLINGLPRDLRCFRKVSCYIMQDDMLLPH
LTVQEAMMVSAHLKLQEKDEGRREMVKEILTALGLLSCANTRTGSLSGGQRKRLAIALELVNNPPVMFFDEPTSGLDSASCFQVVSLMKG
LAQGGRSIICTIHQPSAKLFELFDQLYVLSQGQCVYRGKVCNLVPYLRDLGLNCPTYHNPADFVMEVASGEYGDQNSRLVRAVREGMCDS
DHKRDLGGDAEVNPFLWHRPSEEDSSSMEGCHSFSASCLTQFCILFKRTFLSIMRDSVLTHLRITSHIGIGLLIGLLYLGIGNEAKKVLS
NSGFLFFSMLFLMFAALMPTVLTFPLEMGVFLREHLNYWYSLKAYYLAKTMADVPFQIMFPVAYCSIVYWMTSQPSDAVRFVLFAALGTM
TSLVAQSLGLLIGAASTSLQVATFVGPVTAIPVLLFSGFFVSFDTIPTYLQWMSYISYVRYGFEGVILSIYGLDREDLHCDIDETCHFQK

--------------------------------------------------------------

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Fusion Gene PPI Analysis for PDE9A-ABCG1


check button Go to ChiPPI (Chimeric Protein-Protein interactions) to see the chimeric PPI interaction in

ChiPPI page.


check button Protein-protein interactors with each fusion partner protein in wild-type (BIOGRID-3.4.160)
HgeneHgene's interactorsTgeneTgene's interactors


check button - Retained PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenStill interaction with


check button - Lost PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


check button - Retained PPIs, but lost function due to frame-shift fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


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Related Drugs for PDE9A-ABCG1


check button Drugs targeting genes involved in this fusion gene.
(DrugBank Version 5.1.8 2021-05-08)
PartnerGeneUniProtAccDrugBank IDDrug nameDrug activityDrug typeDrug status

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Related Diseases for PDE9A-ABCG1


check button Diseases associated with fusion partners.
(DisGeNet 4.0)
PartnerGeneDisease IDDisease name# pubmedsSource