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 | Fusion Gene Summary |
| Fusion Gene ORF analysis |
| Fusion Genomic Features |
| Fusion Protein Features |
| Fusion Gene Sequence |
| Fusion Gene PPI analysis |
| Related Drugs |
| Related Diseases |
Fusion gene:PDIA6-FBRSL1 (FusionGDB2 ID:63925) |
Fusion Gene Summary for PDIA6-FBRSL1 |
 Fusion gene summary |
| Fusion gene information | Fusion gene name: PDIA6-FBRSL1 | Fusion gene ID: 63925 | Hgene | Tgene | Gene symbol | PDIA6 | FBRSL1 | Gene ID | 10130 | 57666 |
| Gene name | protein disulfide isomerase family A member 6 | fibrosin like 1 | |
| Synonyms | ERP5|P5|TXNDC7 | - | |
| Cytomap | 2p25.1 | 12q24.33 | |
| Type of gene | protein-coding | protein-coding | |
| Description | protein disulfide-isomerase A6ER protein 5endoplasmic reticulum protein 5epididymis secretory sperm binding proteinprotein disulfide isomerase P5protein disulfide isomerase-associated 6protein disulfide isomerase-related proteinthioredoxin domain c | fibrosin-1-like proteinAUTS2-like proteinHBV X-transactivated gene 9 proteinHBV XAg-transactivated protein 9 | |
| Modification date | 20200313 | 20200313 | |
| UniProtAcc | . | Q9HCM7 | |
| Ensembl transtripts involved in fusion gene | ENST00000272227, ENST00000381611, ENST00000404371, ENST00000404824, ENST00000540494, ENST00000489662, | ENST00000542061, ENST00000261673, ENST00000434748, | |
| Fusion gene scores | * DoF score | 9 X 8 X 5=360 | 9 X 9 X 8=648 |
| # samples | 10 | 9 | |
| ** MAII score | log2(10/360*10)=-1.84799690655495 possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs). DoF>8 and MAII<0 | log2(9/648*10)=-2.84799690655495 possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs). DoF>8 and MAII<0 | |
| Context | PubMed: PDIA6 [Title/Abstract] AND FBRSL1 [Title/Abstract] AND fusion [Title/Abstract] | ||
| Most frequent breakpoint | PDIA6(10933222)-FBRSL1(133102320), # samples:1 | ||
| Anticipated loss of major functional domain due to fusion event. | PDIA6-FBRSL1 seems lost the major protein functional domain in Tgene partner, which is a epigenetic factor due to the frame-shifted ORF. | ||
| * DoF score (Degree of Frequency) = # partners X # break points X # cancer types ** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10) |
| Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez |
| Partner | Gene | GO ID | GO term | PubMed ID |
| Fusion gene breakpoints across PDIA6 (5'-gene) * Click on the image to open the UCSC genome browser with custom track showing this image in a new window. |
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| Fusion gene breakpoints across FBRSL1 (3'-gene) * Click on the image to open the UCSC genome browser with custom track showing this image in a new window. |
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| Fusion gene information from two resources (ChiTars 5.0 and ChimerDB 4.0) * All genome coordinats were lifted-over on hg19. * Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser. |
| Source | Disease | Sample | Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand |
| ChimerDB4 | LUSC | TCGA-79-5596-01A | PDIA6 | chr2 | 10933222 | - | FBRSL1 | chr12 | 133102320 | + |
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Fusion Gene ORF analysis for PDIA6-FBRSL1 |
| Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure. * Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser. |
| ORF | Henst | Tenst | Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand |
| 5CDS-intron | ENST00000272227 | ENST00000542061 | PDIA6 | chr2 | 10933222 | - | FBRSL1 | chr12 | 133102320 | + |
| 5CDS-intron | ENST00000381611 | ENST00000542061 | PDIA6 | chr2 | 10933222 | - | FBRSL1 | chr12 | 133102320 | + |
| 5CDS-intron | ENST00000404371 | ENST00000542061 | PDIA6 | chr2 | 10933222 | - | FBRSL1 | chr12 | 133102320 | + |
| 5CDS-intron | ENST00000404824 | ENST00000542061 | PDIA6 | chr2 | 10933222 | - | FBRSL1 | chr12 | 133102320 | + |
| 5CDS-intron | ENST00000540494 | ENST00000542061 | PDIA6 | chr2 | 10933222 | - | FBRSL1 | chr12 | 133102320 | + |
| Frame-shift | ENST00000381611 | ENST00000261673 | PDIA6 | chr2 | 10933222 | - | FBRSL1 | chr12 | 133102320 | + |
| Frame-shift | ENST00000381611 | ENST00000434748 | PDIA6 | chr2 | 10933222 | - | FBRSL1 | chr12 | 133102320 | + |
| Frame-shift | ENST00000540494 | ENST00000261673 | PDIA6 | chr2 | 10933222 | - | FBRSL1 | chr12 | 133102320 | + |
| Frame-shift | ENST00000540494 | ENST00000434748 | PDIA6 | chr2 | 10933222 | - | FBRSL1 | chr12 | 133102320 | + |
| In-frame | ENST00000272227 | ENST00000261673 | PDIA6 | chr2 | 10933222 | - | FBRSL1 | chr12 | 133102320 | + |
| In-frame | ENST00000272227 | ENST00000434748 | PDIA6 | chr2 | 10933222 | - | FBRSL1 | chr12 | 133102320 | + |
| In-frame | ENST00000404371 | ENST00000261673 | PDIA6 | chr2 | 10933222 | - | FBRSL1 | chr12 | 133102320 | + |
| In-frame | ENST00000404371 | ENST00000434748 | PDIA6 | chr2 | 10933222 | - | FBRSL1 | chr12 | 133102320 | + |
| In-frame | ENST00000404824 | ENST00000261673 | PDIA6 | chr2 | 10933222 | - | FBRSL1 | chr12 | 133102320 | + |
| In-frame | ENST00000404824 | ENST00000434748 | PDIA6 | chr2 | 10933222 | - | FBRSL1 | chr12 | 133102320 | + |
| intron-3CDS | ENST00000489662 | ENST00000261673 | PDIA6 | chr2 | 10933222 | - | FBRSL1 | chr12 | 133102320 | + |
| intron-3CDS | ENST00000489662 | ENST00000434748 | PDIA6 | chr2 | 10933222 | - | FBRSL1 | chr12 | 133102320 | + |
| intron-intron | ENST00000489662 | ENST00000542061 | PDIA6 | chr2 | 10933222 | - | FBRSL1 | chr12 | 133102320 | + |
| ORFfinder result based on the fusion transcript sequence of in-frame fusion genes. |
| Henst | Tenst | Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand | Seq length (transcript) | BP loci (transcript) | Predicted start (transcript) | Predicted stop (transcript) | Seq length (amino acids) |
| ENST00000272227 | PDIA6 | chr2 | 10933222 | - | ENST00000434748 | FBRSL1 | chr12 | 133102320 | + | 4660 | 601 | 52 | 3249 | 1065 |
| ENST00000272227 | PDIA6 | chr2 | 10933222 | - | ENST00000261673 | FBRSL1 | chr12 | 133102320 | + | 3250 | 601 | 52 | 3249 | 1066 |
| ENST00000404371 | PDIA6 | chr2 | 10933222 | - | ENST00000434748 | FBRSL1 | chr12 | 133102320 | + | 5006 | 947 | 338 | 3595 | 1085 |
| ENST00000404371 | PDIA6 | chr2 | 10933222 | - | ENST00000261673 | FBRSL1 | chr12 | 133102320 | + | 3596 | 947 | 338 | 3595 | 1086 |
| ENST00000404824 | PDIA6 | chr2 | 10933222 | - | ENST00000434748 | FBRSL1 | chr12 | 133102320 | + | 5028 | 969 | 345 | 3617 | 1090 |
| ENST00000404824 | PDIA6 | chr2 | 10933222 | - | ENST00000261673 | FBRSL1 | chr12 | 133102320 | + | 3618 | 969 | 345 | 3617 | 1090 |
| DeepORF prediction of the coding potential based on the fusion transcript sequence of in-frame fusion genes. DeepORF is a coding potential classifier based on convolutional neural network by comparing the real Ribo-seq data. If the no-coding score < 0.5 and coding score > 0.5, then the in-frame fusion transcript is predicted as being likely translated. |
| Henst | Tenst | Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand | No-coding score | Coding score |
| ENST00000272227 | ENST00000434748 | PDIA6 | chr2 | 10933222 | - | FBRSL1 | chr12 | 133102320 | + | 0.002492453 | 0.9975076 |
| ENST00000272227 | ENST00000261673 | PDIA6 | chr2 | 10933222 | - | FBRSL1 | chr12 | 133102320 | + | 0.008678545 | 0.9913215 |
| ENST00000404371 | ENST00000434748 | PDIA6 | chr2 | 10933222 | - | FBRSL1 | chr12 | 133102320 | + | 0.003618153 | 0.9963819 |
| ENST00000404371 | ENST00000261673 | PDIA6 | chr2 | 10933222 | - | FBRSL1 | chr12 | 133102320 | + | 0.011679319 | 0.9883207 |
| ENST00000404824 | ENST00000434748 | PDIA6 | chr2 | 10933222 | - | FBRSL1 | chr12 | 133102320 | + | 0.004335448 | 0.99566454 |
| ENST00000404824 | ENST00000261673 | PDIA6 | chr2 | 10933222 | - | FBRSL1 | chr12 | 133102320 | + | 0.014175404 | 0.9858246 |
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Fusion Genomic Features for PDIA6-FBRSL1 |
| FusionAI prediction of the potential fusion gene breakpoint based on the pre-mature RNA sequence context (+/- 5kb of individual partner genes, total 20kb length sequence). FusionAI is a fusion gene breakpoint classifier based on convolutional neural network by comparing the fusion positive and negative sequence context of ~ 20K fusion gene data. From here, we can have the relative potentency of the 20K genomic sequence how individual sequnce will be likely used as the gene fusion breakpoints. |
| Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand | 1-p | p (fusion gene breakpoint) |
| PDIA6 | chr2 | 10933221 | - | FBRSL1 | chr12 | 133102319 | + | 6.04E-11 | 1 |
| PDIA6 | chr2 | 10933221 | - | FBRSL1 | chr12 | 133102319 | + | 6.04E-11 | 1 |
| Distribution of 44 human genomic features loci across 20kb length fusion breakpoint regions. We integrated a total of 44 different types of human genomic feature loci information across five big categories including virus integration sites, repeats, structural variants, chromatin states, and gene expression regulation. More details are in help page. |
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| Distribution of 44 human genomic features loci across 20kb length fusion breakpoint regions that are ovelapped with the top 1% feature importance score regions. More details are in help page. |
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Fusion Protein Features for PDIA6-FBRSL1 |
| Four levels of functional features of fusion genes Go to FGviewer search page for the most frequent breakpoint (https://ccsmweb.uth.edu/FGviewer/chr2:10933222/chr12:133102320) - FGviewer provides the online visualization of the retention search of the protein functional features across DNA, RNA, protein, and pathological levels. - How to search 1. Put your fusion gene symbol. 2. Press the tab key until there will be shown the breakpoint information filled. 4. Go down and press 'Search' tab twice. 4. Go down to have the hyperlink of the search result. 5. Click the hyperlink. 6. See the FGviewer result for your fusion gene. |
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| Main function of each fusion partner protein. (from UniProt) |
| Hgene | Tgene |
| . | FBRSL1 |
| FUNCTION: Transcriptional activator which is required for calcium-dependent dendritic growth and branching in cortical neurons. Recruits CREB-binding protein (CREBBP) to nuclear bodies. Component of the CREST-BRG1 complex, a multiprotein complex that regulates promoter activation by orchestrating a calcium-dependent release of a repressor complex and a recruitment of an activator complex. In resting neurons, transcription of the c-FOS promoter is inhibited by BRG1-dependent recruitment of a phospho-RB1-HDAC1 repressor complex. Upon calcium influx, RB1 is dephosphorylated by calcineurin, which leads to release of the repressor complex. At the same time, there is increased recruitment of CREBBP to the promoter by a CREST-dependent mechanism, which leads to transcriptional activation. The CREST-BRG1 complex also binds to the NR2B promoter, and activity-dependent induction of NR2B expression involves a release of HDAC1 and recruitment of CREBBP (By similarity). {ECO:0000250}. |
| Retention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at * Minus value of BPloci means that the break pointn is located before the CDS. |
| - In-frame and retained protein feature among the 13 regional features. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Protein feature | Protein feature note |
| Hgene | PDIA6 | chr2:10933222 | chr12:133102320 | ENST00000272227 | - | 5 | 13 | 20_133 | 151 | 441.0 | Domain | Thioredoxin 1 |
| Hgene | PDIA6 | chr2:10933222 | chr12:133102320 | ENST00000404371 | - | 7 | 15 | 20_133 | 203 | 493.0 | Domain | Thioredoxin 1 |
| Tgene | FBRSL1 | chr2:10933222 | chr12:133102320 | ENST00000434748 | 1 | 17 | 263_517 | 163 | 1046.0 | Compositional bias | Note=Pro-rich |
| - In-frame and not-retained protein feature among the 13 regional features. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Protein feature | Protein feature note |
| Hgene | PDIA6 | chr2:10933222 | chr12:133102320 | ENST00000272227 | - | 5 | 13 | 422_434 | 151 | 441.0 | Compositional bias | Note=Asp/Glu-rich (acidic) |
| Hgene | PDIA6 | chr2:10933222 | chr12:133102320 | ENST00000404371 | - | 7 | 15 | 422_434 | 203 | 493.0 | Compositional bias | Note=Asp/Glu-rich (acidic) |
| Hgene | PDIA6 | chr2:10933222 | chr12:133102320 | ENST00000272227 | - | 5 | 13 | 154_287 | 151 | 441.0 | Domain | Thioredoxin 2 |
| Hgene | PDIA6 | chr2:10933222 | chr12:133102320 | ENST00000404371 | - | 7 | 15 | 154_287 | 203 | 493.0 | Domain | Thioredoxin 2 |
| Hgene | PDIA6 | chr2:10933222 | chr12:133102320 | ENST00000272227 | - | 5 | 13 | 437_440 | 151 | 441.0 | Motif | Prevents secretion from ER |
| Hgene | PDIA6 | chr2:10933222 | chr12:133102320 | ENST00000404371 | - | 7 | 15 | 437_440 | 203 | 493.0 | Motif | Prevents secretion from ER |
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Fusion Gene Sequence for PDIA6-FBRSL1 |
| For in-frame fusion transcripts, we provide the fusion transcript sequences and fusion amino acid sequences. To have fusion amino acid sequence, we ran ORFfinder and chose the longest ORF among the all predicted ones. |
| >63925_63925_1_PDIA6-FBRSL1_PDIA6_chr2_10933222_ENST00000272227_FBRSL1_chr12_133102320_ENST00000261673_length(transcript)=3250nt_BP=601nt AGCGCCTTCCGGCCCGCCCCCGCGCGGCCGCCCCTCGGACCACCGGACTGGCCTGGGGCGGGACGTGGGCGCGGGGGCGCGGCGTGCGGC ACGCTGCAGGGCTGAAGCGGCGGCGGCGGTGGGGACTGCACGTAGCCCGGCGCTCGGCATGGCTCTCCTGGTGCTCGGTCTGGTGAGCTG TACCTTCTTTCTGGCAGTGAATGGTCTGTATTCCTCTAGTGATGATGTGATCGAATTAACTCCATCGAATTTCAACCGAGAAGTTATTCA GAGTGATAGTTTGTGGCTTGTAGAATTCTATGCTCCATGGTGTGGTCACTGTCAAAGATTAACACCAGAATGGAAGAAAGCAGCAACTGC ATTAAAAGATGTTGTCAAAGTTGGTGCAGTTGATGCAGATAAGCATCATTCCCTAGGAGGTCAGTATGGTGTTCAGGGATTTCCTACCAT TAAGATTTTTGGATCCAACAAAAACAGACCAGAAGATTACCAAGGTGGCAGAACTGGTGAAGCCATTGTAGATGCTGCGCTGAGTGCTCT GCGCCAGCTCGTGAAGGATCGCCTCGGGGGACGGAGCGGAGGATACAGTTCTGGAAAACAAATGAAGGTCACCGTGTCCAAAGGGGGCGA CCGGGACAGTGACGACGACAGCGTCCTCGAAGCCACCAGCTCCCGGGACCCGCTCAGCGATAGCTCTGCGCATGCGGTCTCGGGGAGAGG CTACTCTTGTGACAGCGAGAGCGGCCCGGACGACAAGGCATCCGTGGGCTCTGAGAAGCTCTTTGCGCCGGGAACCGATAAAGGCCCAGC GCTTGAGAAGTCGGAGGCCAAGGCCGGGCCGGTGCCCAAGGTGTCAGGCCTGGAGCGCAGCCGCGAGCTCAGCGCCGAGAGCTTCCTGCC CACTGCCAGCCCCGCGCCCCATGCCGCGCCCTGCCCGGGGCCCCCGCCCGGCTCCCGCGCCAATCCCTTGGTGAAGAAGGAACCCCCCGC CCCGCACCGCCACACCCCGCAGCCGCCACCCCCGCAGCCCCGCGGCCTGCTCCCGACACACGTGCCTGCATCCCTGGGCGCCTTCGCGGG CCACAGCCAGGCGGCAGCCAACGGCCTGCACGGCCTCAGCAGGAGCAGCAGCGCCCCCCTGGGCCTGGGGAAGCACGTGTCGCTGTCGCC ACACGGGCCGGGCCCCCACCTGTCTACCTCACACCTGGCGCTCCGGTCCCAGGCGCAGCACCAGCTCCACGCGGCCATGTTTGCCGCACC CCCGACACTGCCCCCGCCCCCGGCGCTGCCGGCCAGCAGCCTGGTCCTCCCAGGACACCCGGCCGATCACGAGCTGCTCAGGCAAGAGCT GAACACGCGGTTTCTGGTGCAGAGCGCCGAGCGGCCTGGCGCCTCCCTGGGCCCGGGGGCTCTGCTGCGGGCGGAGTTCCATCAGCACCA GCACACACACCAGCACACGCACCAACACACACACCAGCACCAACACACATTCGCCCCCTTCCCCGCAGGGCTGCCCCCGACGCCGCCCGC CGCACCCCCGCCGTTTGACAAGTATGCGCCCAAGCTGGACAGCCCCTACTTCCGACATTCCAGCGTGAGTTTCTTCCCGTCCTTCCCTCC TGCCATCCCGGGACTGCCCACCCTGCTCCCACACCCCGGCCCCTTCGGGTCCCTGCAGGGCGCTTTTCAGCCTAAGGTGTCTGACCCGTA CCGGGCGGTGGTCAAGGTGAGCACGTGTTGGGAAGGCCCGTGGCAAGGGAGGACTCTGGTGCCCCCGGGGCGGCCTCGGGGGGCCCGTGA CAGCAGGAGTCTGCAGAAAACATGGGTGGGGGTGGCACCAGCCCCACTGAGCGCTTCCATCCTGTCGCAGAAGCCGGGGAGGTGGTGTGC CGTGCACGTGCAGATCGCCTGGCAGATCTACCGTCACCAGCAGAAGATAAAGGAGATGCAGCTGGACCCCCACAAGCTGGAGGTGGGTGC AAAGCTGGACCTGTTCGGCAGACCCCCTGCCCCGGGCGTGTTTGCAGGCTTCCACTACCCACAGGACCTGGCCCGGCCCCTCTTCCCCAG CACAGGTGCCGCCCATCCTGCCTCCAACCCATTTGGACCCTCAGCCCATCCTGGCAGCTTCCTGCCCACTGGCCCCCTGACAGACCCTTT CAGCAGACCGAGCACCTTTGGGGGCCTGGGCAGCCTGAGCAGCCACGCCTTTGGGGGCCTGGGCAGCCATGCACTGGCTCCCGGTGGCAG CATCTTTGCCCCCAAGGAGGGCTCCTCCGTGCACGGCCTGCCCAGCCCCCATGAGGCCTGGAACCGACTGCACCGGGCACCGCCCTCCTT CCCGGCTCCGCCCCCGTGGCCCAAGTCCGTGGACGCGGAGCGGGTGTCAGCCCTGACCAACCATGACCGAGAGCCGGACAATGGCAAGGA GGAGCAGGAACGGGACCTCCTGGAGAAGACGCGCCTGCTGAGCCGGGCCTCGCCCGCCACCCCCGCTGGCCACCCCGTCAGCGGCCTCCT GCTCCGGGCCCAGAGCGAGCTGGGCCGGTCCGGGGCCCCCGCGGAGCGCGAGGCCGAACCTCGGGTCAAGGAGAGCCGCTCCCCGGCCAA GGAGGAGGCCGCCAAGATGCCCGCGCGCGCATCCCCGCCCCACAGCAAGGCGGCCCCTGGAGACGTGAAGGTCAAGGAGGAGCGCGGGGA GGACGAGGCCTCCGAGCCCCCGGCGGGCGGCCTGCACCCCGCGCCCCTGCAGCTCGGCCTGGGCCGCGAGCGCCTGGGCGCGCCGGGCTT CGCGTGGGAGCCTTTCCGCGGCCTGGAGCTGCCACGTCGCGCCTTCCCCGCTGCCGCCCCCGCCCCGGGCTCCGCCGCCCTCTTGGAGCC CCCGGAGCGCCCCTACCGCGACCGCGAGCCCCACGGCTACAGCCCCGAGCGCCTGCGCGGGGAGCTGGAGCGCGCGCGGGCCCCGCACCT GCCGCCCGCCGCCCCCGCCTTGGACGGCGCGCTGCTGCCCTCGCTGGGAGCCCTGCACTTCCCGCGCCTCTCGCCCGCCGCGCTGCACAA TGGGCTCCTGGCGCGGACCCCGCCCGCCGCCGCCGCCCTCGGCGCACCGCCCCCCCTGGTGACGGCGGCCGGGCCCCCCACGCCCCCCGG GCCGCCGCGGAGCCGGACTACTCCGCTGGGGGGCCTCGGGCCGGGCGAGGCGCGCGACTACTCCCCGTCCCGAAATCCCCCGGAGGTGGA >63925_63925_1_PDIA6-FBRSL1_PDIA6_chr2_10933222_ENST00000272227_FBRSL1_chr12_133102320_ENST00000261673_length(amino acids)=1066AA_BP=182 MGRDVGAGARRAARCRAEAAAAVGTARSPALGMALLVLGLVSCTFFLAVNGLYSSSDDVIELTPSNFNREVIQSDSLWLVEFYAPWCGHC QRLTPEWKKAATALKDVVKVGAVDADKHHSLGGQYGVQGFPTIKIFGSNKNRPEDYQGGRTGEAIVDAALSALRQLVKDRLGGRSGGYSS GKQMKVTVSKGGDRDSDDDSVLEATSSRDPLSDSSAHAVSGRGYSCDSESGPDDKASVGSEKLFAPGTDKGPALEKSEAKAGPVPKVSGL ERSRELSAESFLPTASPAPHAAPCPGPPPGSRANPLVKKEPPAPHRHTPQPPPPQPRGLLPTHVPASLGAFAGHSQAAANGLHGLSRSSS APLGLGKHVSLSPHGPGPHLSTSHLALRSQAQHQLHAAMFAAPPTLPPPPALPASSLVLPGHPADHELLRQELNTRFLVQSAERPGASLG PGALLRAEFHQHQHTHQHTHQHTHQHQHTFAPFPAGLPPTPPAAPPPFDKYAPKLDSPYFRHSSVSFFPSFPPAIPGLPTLLPHPGPFGS LQGAFQPKVSDPYRAVVKVSTCWEGPWQGRTLVPPGRPRGARDSRSLQKTWVGVAPAPLSASILSQKPGRWCAVHVQIAWQIYRHQQKIK EMQLDPHKLEVGAKLDLFGRPPAPGVFAGFHYPQDLARPLFPSTGAAHPASNPFGPSAHPGSFLPTGPLTDPFSRPSTFGGLGSLSSHAF GGLGSHALAPGGSIFAPKEGSSVHGLPSPHEAWNRLHRAPPSFPAPPPWPKSVDAERVSALTNHDREPDNGKEEQERDLLEKTRLLSRAS PATPAGHPVSGLLLRAQSELGRSGAPAEREAEPRVKESRSPAKEEAAKMPARASPPHSKAAPGDVKVKEERGEDEASEPPAGGLHPAPLQ LGLGRERLGAPGFAWEPFRGLELPRRAFPAAAPAPGSAALLEPPERPYRDREPHGYSPERLRGELERARAPHLPPAAPALDGALLPSLGA -------------------------------------------------------------- >63925_63925_2_PDIA6-FBRSL1_PDIA6_chr2_10933222_ENST00000272227_FBRSL1_chr12_133102320_ENST00000434748_length(transcript)=4660nt_BP=601nt AGCGCCTTCCGGCCCGCCCCCGCGCGGCCGCCCCTCGGACCACCGGACTGGCCTGGGGCGGGACGTGGGCGCGGGGGCGCGGCGTGCGGC ACGCTGCAGGGCTGAAGCGGCGGCGGCGGTGGGGACTGCACGTAGCCCGGCGCTCGGCATGGCTCTCCTGGTGCTCGGTCTGGTGAGCTG TACCTTCTTTCTGGCAGTGAATGGTCTGTATTCCTCTAGTGATGATGTGATCGAATTAACTCCATCGAATTTCAACCGAGAAGTTATTCA GAGTGATAGTTTGTGGCTTGTAGAATTCTATGCTCCATGGTGTGGTCACTGTCAAAGATTAACACCAGAATGGAAGAAAGCAGCAACTGC ATTAAAAGATGTTGTCAAAGTTGGTGCAGTTGATGCAGATAAGCATCATTCCCTAGGAGGTCAGTATGGTGTTCAGGGATTTCCTACCAT TAAGATTTTTGGATCCAACAAAAACAGACCAGAAGATTACCAAGGTGGCAGAACTGGTGAAGCCATTGTAGATGCTGCGCTGAGTGCTCT GCGCCAGCTCGTGAAGGATCGCCTCGGGGGACGGAGCGGAGGATACAGTTCTGGAAAACAAATGAAGGTCACCGTGTCCAAAGGGGGCGA CCGGGACAGTGACGACGACAGCGTCCTCGAAGCCACCAGCTCCCGGGACCCGCTCAGCGATAGCTCTGCGCATGCGGTCTCGGGGAGAGG CTACTCTTGTGACAGCGAGAGCGGCCCGGACGACAAGGCATCCGTGGGCTCTGAGAAGCTCTTTGCGCCGGGAACCGATAAAGGCCCAGC GCTTGAGAAGTCGGAGGCCAAGGCCGGGCCGGTGCCCAAGGTGTCAGGCCTGGAGCGCAGCCGCGAGCTCAGCGCCGAGAGCTTCCTGCC CACTGCCAGCCCCGCGCCCCATGCCGCGCCCTGCCCGGGGCCCCCGCCCGGCTCCCGCGCCAATCCCTTGGTGAAGAAGGAACCCCCCGC CCCGCACCGCCACACCCCGCAGCCGCCACCCCCGCAGCCCCGCGGCCTGCTCCCGACACACGTGCCTGCATCCCTGGGCGCCTTCGCGGG CCACAGCCAGGCGGCAGCCAACGGCCTGCACGGCCTCAGCAGGAGCAGCAGCGCCCCCCTGGGCCTGGGGAAGCACGTGTCGCTGTCGCC ACACGGGCCGGGCCCCCACCTGTCTACCTCACACCTGGCGCTCCGGTCCCAGGCGCAGCACCAGCTCCACGCGGCCATGTTTGCCGCACC CCCGACACTGCCCCCGCCCCCGGCGCTGCCGGCCAGCAGCCTGGTCCTCCCAGGACACCCGGCCGATCACGAGCTGCTCAGGCAAGAGCT GAACACGCGGTTTCTGGTGCAGAGCGCCGAGCGGCCTGGCGCCTCCCTGGGCCCGGGGGCTCTGCTGCGGGCGGAGTTCCATCAGCACCA GCACACACACCAGCACACGCACCAACACACACACCAGCACCAACACACATTCGCCCCCTTCCCCGCAGGGCTGCCCCCGACGCCGCCCGC CGCACCCCCGCCGTTTGACAAGTATGCGCCCAAGCTGGACAGCCCCTACTTCCGACATTCCAGCGTGAGTTTCTTCCCGTCCTTCCCTCC TGCCATCCCGGGACTGCCCACCCTGCTCCCACACCCCGGCCCCTTCGGGTCCCTGCAGGGCGCTTTTCAGCCTAAGGTGTCTGACCCGTA CCGGGCGGTGGTCAAGGTGAGCACGTGTTGGGAAGGCCCGTGGCAAGGGAGGACTCTGGTGCCCCCGGGGCGGCCTCGGGGGGCCCGTGA CAGCAGGAGTCTGCAGAAAACATGGGTGGGGGTGGCACCAGCCCCACTGAGCGCTTCCATCCTGTCGCAGAAGCCGGGGAGGTGGTGTGC CGTGCACGTGCAGATCGCCTGGCAGATCTACCGTCACCAGCAGAAGATAAAGGAGATGCAGCTGGACCCCCACAAGCTGGAGGTGGGTGC AAAGCTGGACCTGTTCGGCAGACCCCCTGCCCCGGGCGTGTTTGCAGGCTTCCACTACCCACAGGACCTGGCCCGGCCCCTCTTCCCCAG CACAGGTGCCGCCCATCCTGCCTCCAACCCATTTGGACCCTCAGCCCATCCTGGCAGCTTCCTGCCCACTGGCCCCCTGACAGACCCTTT CAGCAGACCGAGCACCTTTGGGGGCCTGGGCAGCCTGAGCAGCCACGCCTTTGGGGGCCTGGGCAGCCATGCACTGGCTCCCGGTGGCAG CATCTTTGCCCCCAAGGAGGGCTCCTCCGTGCACGGCCTGCCCAGCCCCCATGAGGCCTGGAACCGACTGCACCGGGCACCGCCCTCCTT CCCGGCTCCGCCCCCGTGGCCCAAGTCCGTGGACGCGGAGCGGGTGTCAGCCCTGACCAACCATGACCGAGAGCCGGACAATGGCAAGGA GGAGCAGGAACGGGACCTCCTGGAGAAGACGCGCCTGCTGAGCCGGGCCTCGCCCGCCACCCCCGCTGGCCACCCCGTCAGCGGCCTCCT GCTCCGGGCCCAGAGCGAGCTGGGCCGGTCCGGGGCCCCCGCGGAGCGCGAGGCCGAACCTCGGGTCAAGGAGAGCCGCTCCCCGGCCAA GGAGGAGGCCGCCAAGATGCCCGCGCGCGCATCCCCGCCCCACAGCAAGGCGGCCCCTGGAGACGTGAAGGTCAAGGAGGAGCGCGGGGA GGACGAGGCCTCCGAGCCCCCGGCGGGCGGCCTGCACCCCGCGCCCCTGCAGCTCGGCCTGGGCCGCGAGCGCCTGGGCGCGCCGGGCTT CGCGTGGGAGCCTTTCCGCGGCCTGGAGCTGCCACGTCGCGCCTTCCCCGCTGCCGCCCCCGCCCCGGGCTCCGCCGCCCTCTTGGAGCC CCCGGAGCGCCCCTACCGCGACCGCGAGCCCCACGGCTACAGCCCCGAGCGCCTGCGCGGGGAGCTGGAGCGCGCGCGGGCCCCGCACCT GCCGCCCGCCGCCCCCGCCTTGGACGGCGCGCTGCTGCCCTCGCTGGGAGCCCTGCACTTCCCGCGCCTCTCGCCCGCCGCGCTGCACAA TGGGCTCCTGGCGCGGACCCCGCCCGCCGCCGCCGCCCTCGGCGCACCGCCCCCCCTGGTGACGGCGGCCGGGCCCCCCACGCCCCCCGG GCCGCCGCGGAGCCGGACTACTCCGCTGGGGGGCCTCGGGCCGGGCGAGGCGCGCGACTACTCCCCGTCCCGAAATCCCCCGGAGGTGGA GGCGCGGTAGCCCCGGGGCCGCAGACGCCTCTCCGAGCGGAGCGCACCGCTGTCCGTCTCTCCATCAGTTCCTAGAACTCAAGCACAGCT CCCGCCGATCCTGGGGCGGCGCCGCCTCTCCACCCGCAGCCTGCGGAGGCGGGGACTTGGGTGTCGGCTTTTCTGAGGGTGATCTTTTGT TTTCCGAGTTTGGGATTCGGCTGTTGGGAAAAAAAAATCGCGTTTGTACCTTTTCCCCCCACAGATGAGAAGTGTTTGTAATGGATTTGT ATTTTTCTTAATTTTATGCTCTTTAGACGTTTAAAAGAACCAAAAAAGAAACTTTTGCTTCTTCGTTTTCGGTTGGGATTTGCAGTTTAA TGGCCTCAGATCCTTCTCCAGATCCCCAGGGTTTCTTTGTCTTATTTATGGAGAAAAACCGGTCACTTTGTCCAGCGCACTGTGAGGCCC CCACTCAGGCCAGCCCTGGCCCCCCCTTGGTACTTGGAACCGAAGTTACAGATTATATTAAAATAATAATGTACAAAACTTTGTTTTTTT GCCTTATTATGCAGAAGTGTAATTTCTTTTTTGGTTTGTTTTTTTAAAAGCAAACGAAACGTGTAAATAGTCTGTTGATATAAATATATG ACGTTACTAAATTCTTAATCTAGATAGACTTTATAAAAACCGTTTCCAGAAACCCCTCTGGTTGTTTGTCTAACATGGTCACAAAAACCC AGGCGCTGCTGGCTGTAAACATTATCAGAAGTTTAATGGCAGCAACTTTCCTTCAACTATGCAAGCGCTTCCCGGCGGCTCTGCTGGTTG GGGGAGGAAGGTTCCGCCAGCGACCTCCCAGCCCCTGGGTCCGTGGAGGGGTTGGGTCCCCCAGCAGAGCCCCTGGGCCAGCAGAACAGC ACTCCTGGGCGGCTCCTGTGGGCTTCAGGACTGGCCGGCTCCAGCCGCAAGGGCGATGCTGTGGACGTTTGTGTGGATGGTGCAGTGTTC TTGGAATCTGTAGACCAGATCGGTGGAGGTATAGAAGTGCAAGAGTCTAAAGGCTGATTTTACACACACACACACACACACACACACACA CACAAAATCACTGCTGTGTGTTTTCTTCCGCCTGAGGCATCAGCGTCACCTCGGTGTGGTCGTCGCCTCCCAGGCCCTTGGCCTGGCCTC CTCTCAGTTTGGGTTTTGCCCTCACCCACATGAGCCCCCCCATGCCCTGCCCCCCTTGCGGCCTTTTGTGTTCCCCGATGTCTGGGCTGT GTCCCTGCCGGGATTCCCAGCCTTCGGGGTCAGCCGTCGAGCCACTTGCTTTGCTCAGTTCTGTGTTTCAGCCACATTTCCACGGTGGAC >63925_63925_2_PDIA6-FBRSL1_PDIA6_chr2_10933222_ENST00000272227_FBRSL1_chr12_133102320_ENST00000434748_length(amino acids)=1065AA_BP=182 MGRDVGAGARRAARCRAEAAAAVGTARSPALGMALLVLGLVSCTFFLAVNGLYSSSDDVIELTPSNFNREVIQSDSLWLVEFYAPWCGHC QRLTPEWKKAATALKDVVKVGAVDADKHHSLGGQYGVQGFPTIKIFGSNKNRPEDYQGGRTGEAIVDAALSALRQLVKDRLGGRSGGYSS GKQMKVTVSKGGDRDSDDDSVLEATSSRDPLSDSSAHAVSGRGYSCDSESGPDDKASVGSEKLFAPGTDKGPALEKSEAKAGPVPKVSGL ERSRELSAESFLPTASPAPHAAPCPGPPPGSRANPLVKKEPPAPHRHTPQPPPPQPRGLLPTHVPASLGAFAGHSQAAANGLHGLSRSSS APLGLGKHVSLSPHGPGPHLSTSHLALRSQAQHQLHAAMFAAPPTLPPPPALPASSLVLPGHPADHELLRQELNTRFLVQSAERPGASLG PGALLRAEFHQHQHTHQHTHQHTHQHQHTFAPFPAGLPPTPPAAPPPFDKYAPKLDSPYFRHSSVSFFPSFPPAIPGLPTLLPHPGPFGS LQGAFQPKVSDPYRAVVKVSTCWEGPWQGRTLVPPGRPRGARDSRSLQKTWVGVAPAPLSASILSQKPGRWCAVHVQIAWQIYRHQQKIK EMQLDPHKLEVGAKLDLFGRPPAPGVFAGFHYPQDLARPLFPSTGAAHPASNPFGPSAHPGSFLPTGPLTDPFSRPSTFGGLGSLSSHAF GGLGSHALAPGGSIFAPKEGSSVHGLPSPHEAWNRLHRAPPSFPAPPPWPKSVDAERVSALTNHDREPDNGKEEQERDLLEKTRLLSRAS PATPAGHPVSGLLLRAQSELGRSGAPAEREAEPRVKESRSPAKEEAAKMPARASPPHSKAAPGDVKVKEERGEDEASEPPAGGLHPAPLQ LGLGRERLGAPGFAWEPFRGLELPRRAFPAAAPAPGSAALLEPPERPYRDREPHGYSPERLRGELERARAPHLPPAAPALDGALLPSLGA -------------------------------------------------------------- >63925_63925_3_PDIA6-FBRSL1_PDIA6_chr2_10933222_ENST00000404371_FBRSL1_chr12_133102320_ENST00000261673_length(transcript)=3596nt_BP=947nt AACCGAGGGTGCCCGCTGCAAGGTTAGGTCTCCTGGCCTCGTGCTTCAAACAGGAATTAATAGAATCCCACCAGGTGGTGTTTGTGAGGC GTAGATGGCGAGGATATCTGCAGCTGCAGTTTGCTCATTCTCACGGCTGCACTGCATTGCACTGTGTGAGCAGAACACAATTTATCCTTC CACTGCTGATGGGCATTTGGGCGGTTTGCAGTTTGGGATCTGGCCAGTTCTGCTGTTGTGAGCATTCTTAAGCCTGCCTTTCGGTGAATT CACACGCCCGTGGGGACGCTCACTCTCAGAGCACAGCTTCCAGAGGAGAGAAGATACCCCCAGCATCCATGAGAAGAGACCTCCGGGAGA AGCTTGTGTGGGTGTGCCGACCACTGGCCCCAGTTGAGGTCCCAGCCAACATCAGCTCCGACTTCCAGCCATGCTCACCAACTTCTCCTG CCCACTCCCTATCAAGGAAAAGTCCCATAATGTATCCATCAACCACCATGGCTAATGCACCCGGTCTGGTGAGCTGTACCTTCTTTCTGG CAGTGAATGGTCTGTATTCCTCTAGTGATGATGTGATCGAATTAACTCCATCGAATTTCAACCGAGAAGTTATTCAGAGTGATAGTTTGT GGCTTGTAGAATTCTATGCTCCATGGTGTGGTCACTGTCAAAGATTAACACCAGAATGGAAGAAAGCAGCAACTGCATTAAAAGATGTTG TCAAAGTTGGTGCAGTTGATGCAGATAAGCATCATTCCCTAGGAGGTCAGTATGGTGTTCAGGGATTTCCTACCATTAAGATTTTTGGAT CCAACAAAAACAGACCAGAAGATTACCAAGGTGGCAGAACTGGTGAAGCCATTGTAGATGCTGCGCTGAGTGCTCTGCGCCAGCTCGTGA AGGATCGCCTCGGGGGACGGAGCGGAGGATACAGTTCTGGAAAACAAATGAAGGTCACCGTGTCCAAAGGGGGCGACCGGGACAGTGACG ACGACAGCGTCCTCGAAGCCACCAGCTCCCGGGACCCGCTCAGCGATAGCTCTGCGCATGCGGTCTCGGGGAGAGGCTACTCTTGTGACA GCGAGAGCGGCCCGGACGACAAGGCATCCGTGGGCTCTGAGAAGCTCTTTGCGCCGGGAACCGATAAAGGCCCAGCGCTTGAGAAGTCGG AGGCCAAGGCCGGGCCGGTGCCCAAGGTGTCAGGCCTGGAGCGCAGCCGCGAGCTCAGCGCCGAGAGCTTCCTGCCCACTGCCAGCCCCG CGCCCCATGCCGCGCCCTGCCCGGGGCCCCCGCCCGGCTCCCGCGCCAATCCCTTGGTGAAGAAGGAACCCCCCGCCCCGCACCGCCACA CCCCGCAGCCGCCACCCCCGCAGCCCCGCGGCCTGCTCCCGACACACGTGCCTGCATCCCTGGGCGCCTTCGCGGGCCACAGCCAGGCGG CAGCCAACGGCCTGCACGGCCTCAGCAGGAGCAGCAGCGCCCCCCTGGGCCTGGGGAAGCACGTGTCGCTGTCGCCACACGGGCCGGGCC CCCACCTGTCTACCTCACACCTGGCGCTCCGGTCCCAGGCGCAGCACCAGCTCCACGCGGCCATGTTTGCCGCACCCCCGACACTGCCCC CGCCCCCGGCGCTGCCGGCCAGCAGCCTGGTCCTCCCAGGACACCCGGCCGATCACGAGCTGCTCAGGCAAGAGCTGAACACGCGGTTTC TGGTGCAGAGCGCCGAGCGGCCTGGCGCCTCCCTGGGCCCGGGGGCTCTGCTGCGGGCGGAGTTCCATCAGCACCAGCACACACACCAGC ACACGCACCAACACACACACCAGCACCAACACACATTCGCCCCCTTCCCCGCAGGGCTGCCCCCGACGCCGCCCGCCGCACCCCCGCCGT TTGACAAGTATGCGCCCAAGCTGGACAGCCCCTACTTCCGACATTCCAGCGTGAGTTTCTTCCCGTCCTTCCCTCCTGCCATCCCGGGAC TGCCCACCCTGCTCCCACACCCCGGCCCCTTCGGGTCCCTGCAGGGCGCTTTTCAGCCTAAGGTGTCTGACCCGTACCGGGCGGTGGTCA AGGTGAGCACGTGTTGGGAAGGCCCGTGGCAAGGGAGGACTCTGGTGCCCCCGGGGCGGCCTCGGGGGGCCCGTGACAGCAGGAGTCTGC AGAAAACATGGGTGGGGGTGGCACCAGCCCCACTGAGCGCTTCCATCCTGTCGCAGAAGCCGGGGAGGTGGTGTGCCGTGCACGTGCAGA TCGCCTGGCAGATCTACCGTCACCAGCAGAAGATAAAGGAGATGCAGCTGGACCCCCACAAGCTGGAGGTGGGTGCAAAGCTGGACCTGT TCGGCAGACCCCCTGCCCCGGGCGTGTTTGCAGGCTTCCACTACCCACAGGACCTGGCCCGGCCCCTCTTCCCCAGCACAGGTGCCGCCC ATCCTGCCTCCAACCCATTTGGACCCTCAGCCCATCCTGGCAGCTTCCTGCCCACTGGCCCCCTGACAGACCCTTTCAGCAGACCGAGCA CCTTTGGGGGCCTGGGCAGCCTGAGCAGCCACGCCTTTGGGGGCCTGGGCAGCCATGCACTGGCTCCCGGTGGCAGCATCTTTGCCCCCA AGGAGGGCTCCTCCGTGCACGGCCTGCCCAGCCCCCATGAGGCCTGGAACCGACTGCACCGGGCACCGCCCTCCTTCCCGGCTCCGCCCC CGTGGCCCAAGTCCGTGGACGCGGAGCGGGTGTCAGCCCTGACCAACCATGACCGAGAGCCGGACAATGGCAAGGAGGAGCAGGAACGGG ACCTCCTGGAGAAGACGCGCCTGCTGAGCCGGGCCTCGCCCGCCACCCCCGCTGGCCACCCCGTCAGCGGCCTCCTGCTCCGGGCCCAGA GCGAGCTGGGCCGGTCCGGGGCCCCCGCGGAGCGCGAGGCCGAACCTCGGGTCAAGGAGAGCCGCTCCCCGGCCAAGGAGGAGGCCGCCA AGATGCCCGCGCGCGCATCCCCGCCCCACAGCAAGGCGGCCCCTGGAGACGTGAAGGTCAAGGAGGAGCGCGGGGAGGACGAGGCCTCCG AGCCCCCGGCGGGCGGCCTGCACCCCGCGCCCCTGCAGCTCGGCCTGGGCCGCGAGCGCCTGGGCGCGCCGGGCTTCGCGTGGGAGCCTT TCCGCGGCCTGGAGCTGCCACGTCGCGCCTTCCCCGCTGCCGCCCCCGCCCCGGGCTCCGCCGCCCTCTTGGAGCCCCCGGAGCGCCCCT ACCGCGACCGCGAGCCCCACGGCTACAGCCCCGAGCGCCTGCGCGGGGAGCTGGAGCGCGCGCGGGCCCCGCACCTGCCGCCCGCCGCCC CCGCCTTGGACGGCGCGCTGCTGCCCTCGCTGGGAGCCCTGCACTTCCCGCGCCTCTCGCCCGCCGCGCTGCACAATGGGCTCCTGGCGC GGACCCCGCCCGCCGCCGCCGCCCTCGGCGCACCGCCCCCCCTGGTGACGGCGGCCGGGCCCCCCACGCCCCCCGGGCCGCCGCGGAGCC >63925_63925_3_PDIA6-FBRSL1_PDIA6_chr2_10933222_ENST00000404371_FBRSL1_chr12_133102320_ENST00000261673_length(amino acids)=1086AA_BP=202 MRRDLREKLVWVCRPLAPVEVPANISSDFQPCSPTSPAHSLSRKSPIMYPSTTMANAPGLVSCTFFLAVNGLYSSSDDVIELTPSNFNRE VIQSDSLWLVEFYAPWCGHCQRLTPEWKKAATALKDVVKVGAVDADKHHSLGGQYGVQGFPTIKIFGSNKNRPEDYQGGRTGEAIVDAAL SALRQLVKDRLGGRSGGYSSGKQMKVTVSKGGDRDSDDDSVLEATSSRDPLSDSSAHAVSGRGYSCDSESGPDDKASVGSEKLFAPGTDK GPALEKSEAKAGPVPKVSGLERSRELSAESFLPTASPAPHAAPCPGPPPGSRANPLVKKEPPAPHRHTPQPPPPQPRGLLPTHVPASLGA FAGHSQAAANGLHGLSRSSSAPLGLGKHVSLSPHGPGPHLSTSHLALRSQAQHQLHAAMFAAPPTLPPPPALPASSLVLPGHPADHELLR QELNTRFLVQSAERPGASLGPGALLRAEFHQHQHTHQHTHQHTHQHQHTFAPFPAGLPPTPPAAPPPFDKYAPKLDSPYFRHSSVSFFPS FPPAIPGLPTLLPHPGPFGSLQGAFQPKVSDPYRAVVKVSTCWEGPWQGRTLVPPGRPRGARDSRSLQKTWVGVAPAPLSASILSQKPGR WCAVHVQIAWQIYRHQQKIKEMQLDPHKLEVGAKLDLFGRPPAPGVFAGFHYPQDLARPLFPSTGAAHPASNPFGPSAHPGSFLPTGPLT DPFSRPSTFGGLGSLSSHAFGGLGSHALAPGGSIFAPKEGSSVHGLPSPHEAWNRLHRAPPSFPAPPPWPKSVDAERVSALTNHDREPDN GKEEQERDLLEKTRLLSRASPATPAGHPVSGLLLRAQSELGRSGAPAEREAEPRVKESRSPAKEEAAKMPARASPPHSKAAPGDVKVKEE RGEDEASEPPAGGLHPAPLQLGLGRERLGAPGFAWEPFRGLELPRRAFPAAAPAPGSAALLEPPERPYRDREPHGYSPERLRGELERARA PHLPPAAPALDGALLPSLGALHFPRLSPAALHNGLLARTPPAAAALGAPPPLVTAAGPPTPPGPPRSRTTPLGGLGPGEARDYSPSRNPP -------------------------------------------------------------- >63925_63925_4_PDIA6-FBRSL1_PDIA6_chr2_10933222_ENST00000404371_FBRSL1_chr12_133102320_ENST00000434748_length(transcript)=5006nt_BP=947nt AACCGAGGGTGCCCGCTGCAAGGTTAGGTCTCCTGGCCTCGTGCTTCAAACAGGAATTAATAGAATCCCACCAGGTGGTGTTTGTGAGGC GTAGATGGCGAGGATATCTGCAGCTGCAGTTTGCTCATTCTCACGGCTGCACTGCATTGCACTGTGTGAGCAGAACACAATTTATCCTTC CACTGCTGATGGGCATTTGGGCGGTTTGCAGTTTGGGATCTGGCCAGTTCTGCTGTTGTGAGCATTCTTAAGCCTGCCTTTCGGTGAATT CACACGCCCGTGGGGACGCTCACTCTCAGAGCACAGCTTCCAGAGGAGAGAAGATACCCCCAGCATCCATGAGAAGAGACCTCCGGGAGA AGCTTGTGTGGGTGTGCCGACCACTGGCCCCAGTTGAGGTCCCAGCCAACATCAGCTCCGACTTCCAGCCATGCTCACCAACTTCTCCTG CCCACTCCCTATCAAGGAAAAGTCCCATAATGTATCCATCAACCACCATGGCTAATGCACCCGGTCTGGTGAGCTGTACCTTCTTTCTGG CAGTGAATGGTCTGTATTCCTCTAGTGATGATGTGATCGAATTAACTCCATCGAATTTCAACCGAGAAGTTATTCAGAGTGATAGTTTGT GGCTTGTAGAATTCTATGCTCCATGGTGTGGTCACTGTCAAAGATTAACACCAGAATGGAAGAAAGCAGCAACTGCATTAAAAGATGTTG TCAAAGTTGGTGCAGTTGATGCAGATAAGCATCATTCCCTAGGAGGTCAGTATGGTGTTCAGGGATTTCCTACCATTAAGATTTTTGGAT CCAACAAAAACAGACCAGAAGATTACCAAGGTGGCAGAACTGGTGAAGCCATTGTAGATGCTGCGCTGAGTGCTCTGCGCCAGCTCGTGA AGGATCGCCTCGGGGGACGGAGCGGAGGATACAGTTCTGGAAAACAAATGAAGGTCACCGTGTCCAAAGGGGGCGACCGGGACAGTGACG ACGACAGCGTCCTCGAAGCCACCAGCTCCCGGGACCCGCTCAGCGATAGCTCTGCGCATGCGGTCTCGGGGAGAGGCTACTCTTGTGACA GCGAGAGCGGCCCGGACGACAAGGCATCCGTGGGCTCTGAGAAGCTCTTTGCGCCGGGAACCGATAAAGGCCCAGCGCTTGAGAAGTCGG AGGCCAAGGCCGGGCCGGTGCCCAAGGTGTCAGGCCTGGAGCGCAGCCGCGAGCTCAGCGCCGAGAGCTTCCTGCCCACTGCCAGCCCCG CGCCCCATGCCGCGCCCTGCCCGGGGCCCCCGCCCGGCTCCCGCGCCAATCCCTTGGTGAAGAAGGAACCCCCCGCCCCGCACCGCCACA CCCCGCAGCCGCCACCCCCGCAGCCCCGCGGCCTGCTCCCGACACACGTGCCTGCATCCCTGGGCGCCTTCGCGGGCCACAGCCAGGCGG CAGCCAACGGCCTGCACGGCCTCAGCAGGAGCAGCAGCGCCCCCCTGGGCCTGGGGAAGCACGTGTCGCTGTCGCCACACGGGCCGGGCC CCCACCTGTCTACCTCACACCTGGCGCTCCGGTCCCAGGCGCAGCACCAGCTCCACGCGGCCATGTTTGCCGCACCCCCGACACTGCCCC CGCCCCCGGCGCTGCCGGCCAGCAGCCTGGTCCTCCCAGGACACCCGGCCGATCACGAGCTGCTCAGGCAAGAGCTGAACACGCGGTTTC TGGTGCAGAGCGCCGAGCGGCCTGGCGCCTCCCTGGGCCCGGGGGCTCTGCTGCGGGCGGAGTTCCATCAGCACCAGCACACACACCAGC ACACGCACCAACACACACACCAGCACCAACACACATTCGCCCCCTTCCCCGCAGGGCTGCCCCCGACGCCGCCCGCCGCACCCCCGCCGT TTGACAAGTATGCGCCCAAGCTGGACAGCCCCTACTTCCGACATTCCAGCGTGAGTTTCTTCCCGTCCTTCCCTCCTGCCATCCCGGGAC TGCCCACCCTGCTCCCACACCCCGGCCCCTTCGGGTCCCTGCAGGGCGCTTTTCAGCCTAAGGTGTCTGACCCGTACCGGGCGGTGGTCA AGGTGAGCACGTGTTGGGAAGGCCCGTGGCAAGGGAGGACTCTGGTGCCCCCGGGGCGGCCTCGGGGGGCCCGTGACAGCAGGAGTCTGC AGAAAACATGGGTGGGGGTGGCACCAGCCCCACTGAGCGCTTCCATCCTGTCGCAGAAGCCGGGGAGGTGGTGTGCCGTGCACGTGCAGA TCGCCTGGCAGATCTACCGTCACCAGCAGAAGATAAAGGAGATGCAGCTGGACCCCCACAAGCTGGAGGTGGGTGCAAAGCTGGACCTGT TCGGCAGACCCCCTGCCCCGGGCGTGTTTGCAGGCTTCCACTACCCACAGGACCTGGCCCGGCCCCTCTTCCCCAGCACAGGTGCCGCCC ATCCTGCCTCCAACCCATTTGGACCCTCAGCCCATCCTGGCAGCTTCCTGCCCACTGGCCCCCTGACAGACCCTTTCAGCAGACCGAGCA CCTTTGGGGGCCTGGGCAGCCTGAGCAGCCACGCCTTTGGGGGCCTGGGCAGCCATGCACTGGCTCCCGGTGGCAGCATCTTTGCCCCCA AGGAGGGCTCCTCCGTGCACGGCCTGCCCAGCCCCCATGAGGCCTGGAACCGACTGCACCGGGCACCGCCCTCCTTCCCGGCTCCGCCCC CGTGGCCCAAGTCCGTGGACGCGGAGCGGGTGTCAGCCCTGACCAACCATGACCGAGAGCCGGACAATGGCAAGGAGGAGCAGGAACGGG ACCTCCTGGAGAAGACGCGCCTGCTGAGCCGGGCCTCGCCCGCCACCCCCGCTGGCCACCCCGTCAGCGGCCTCCTGCTCCGGGCCCAGA GCGAGCTGGGCCGGTCCGGGGCCCCCGCGGAGCGCGAGGCCGAACCTCGGGTCAAGGAGAGCCGCTCCCCGGCCAAGGAGGAGGCCGCCA AGATGCCCGCGCGCGCATCCCCGCCCCACAGCAAGGCGGCCCCTGGAGACGTGAAGGTCAAGGAGGAGCGCGGGGAGGACGAGGCCTCCG AGCCCCCGGCGGGCGGCCTGCACCCCGCGCCCCTGCAGCTCGGCCTGGGCCGCGAGCGCCTGGGCGCGCCGGGCTTCGCGTGGGAGCCTT TCCGCGGCCTGGAGCTGCCACGTCGCGCCTTCCCCGCTGCCGCCCCCGCCCCGGGCTCCGCCGCCCTCTTGGAGCCCCCGGAGCGCCCCT ACCGCGACCGCGAGCCCCACGGCTACAGCCCCGAGCGCCTGCGCGGGGAGCTGGAGCGCGCGCGGGCCCCGCACCTGCCGCCCGCCGCCC CCGCCTTGGACGGCGCGCTGCTGCCCTCGCTGGGAGCCCTGCACTTCCCGCGCCTCTCGCCCGCCGCGCTGCACAATGGGCTCCTGGCGC GGACCCCGCCCGCCGCCGCCGCCCTCGGCGCACCGCCCCCCCTGGTGACGGCGGCCGGGCCCCCCACGCCCCCCGGGCCGCCGCGGAGCC GGACTACTCCGCTGGGGGGCCTCGGGCCGGGCGAGGCGCGCGACTACTCCCCGTCCCGAAATCCCCCGGAGGTGGAGGCGCGGTAGCCCC GGGGCCGCAGACGCCTCTCCGAGCGGAGCGCACCGCTGTCCGTCTCTCCATCAGTTCCTAGAACTCAAGCACAGCTCCCGCCGATCCTGG GGCGGCGCCGCCTCTCCACCCGCAGCCTGCGGAGGCGGGGACTTGGGTGTCGGCTTTTCTGAGGGTGATCTTTTGTTTTCCGAGTTTGGG ATTCGGCTGTTGGGAAAAAAAAATCGCGTTTGTACCTTTTCCCCCCACAGATGAGAAGTGTTTGTAATGGATTTGTATTTTTCTTAATTT TATGCTCTTTAGACGTTTAAAAGAACCAAAAAAGAAACTTTTGCTTCTTCGTTTTCGGTTGGGATTTGCAGTTTAATGGCCTCAGATCCT TCTCCAGATCCCCAGGGTTTCTTTGTCTTATTTATGGAGAAAAACCGGTCACTTTGTCCAGCGCACTGTGAGGCCCCCACTCAGGCCAGC CCTGGCCCCCCCTTGGTACTTGGAACCGAAGTTACAGATTATATTAAAATAATAATGTACAAAACTTTGTTTTTTTGCCTTATTATGCAG AAGTGTAATTTCTTTTTTGGTTTGTTTTTTTAAAAGCAAACGAAACGTGTAAATAGTCTGTTGATATAAATATATGACGTTACTAAATTC TTAATCTAGATAGACTTTATAAAAACCGTTTCCAGAAACCCCTCTGGTTGTTTGTCTAACATGGTCACAAAAACCCAGGCGCTGCTGGCT GTAAACATTATCAGAAGTTTAATGGCAGCAACTTTCCTTCAACTATGCAAGCGCTTCCCGGCGGCTCTGCTGGTTGGGGGAGGAAGGTTC CGCCAGCGACCTCCCAGCCCCTGGGTCCGTGGAGGGGTTGGGTCCCCCAGCAGAGCCCCTGGGCCAGCAGAACAGCACTCCTGGGCGGCT CCTGTGGGCTTCAGGACTGGCCGGCTCCAGCCGCAAGGGCGATGCTGTGGACGTTTGTGTGGATGGTGCAGTGTTCTTGGAATCTGTAGA CCAGATCGGTGGAGGTATAGAAGTGCAAGAGTCTAAAGGCTGATTTTACACACACACACACACACACACACACACACACAAAATCACTGC TGTGTGTTTTCTTCCGCCTGAGGCATCAGCGTCACCTCGGTGTGGTCGTCGCCTCCCAGGCCCTTGGCCTGGCCTCCTCTCAGTTTGGGT TTTGCCCTCACCCACATGAGCCCCCCCATGCCCTGCCCCCCTTGCGGCCTTTTGTGTTCCCCGATGTCTGGGCTGTGTCCCTGCCGGGAT TCCCAGCCTTCGGGGTCAGCCGTCGAGCCACTTGCTTTGCTCAGTTCTGTGTTTCAGCCACATTTCCACGGTGGACCCTGTTTGTTTTAA >63925_63925_4_PDIA6-FBRSL1_PDIA6_chr2_10933222_ENST00000404371_FBRSL1_chr12_133102320_ENST00000434748_length(amino acids)=1085AA_BP=202 MRRDLREKLVWVCRPLAPVEVPANISSDFQPCSPTSPAHSLSRKSPIMYPSTTMANAPGLVSCTFFLAVNGLYSSSDDVIELTPSNFNRE VIQSDSLWLVEFYAPWCGHCQRLTPEWKKAATALKDVVKVGAVDADKHHSLGGQYGVQGFPTIKIFGSNKNRPEDYQGGRTGEAIVDAAL SALRQLVKDRLGGRSGGYSSGKQMKVTVSKGGDRDSDDDSVLEATSSRDPLSDSSAHAVSGRGYSCDSESGPDDKASVGSEKLFAPGTDK GPALEKSEAKAGPVPKVSGLERSRELSAESFLPTASPAPHAAPCPGPPPGSRANPLVKKEPPAPHRHTPQPPPPQPRGLLPTHVPASLGA FAGHSQAAANGLHGLSRSSSAPLGLGKHVSLSPHGPGPHLSTSHLALRSQAQHQLHAAMFAAPPTLPPPPALPASSLVLPGHPADHELLR QELNTRFLVQSAERPGASLGPGALLRAEFHQHQHTHQHTHQHTHQHQHTFAPFPAGLPPTPPAAPPPFDKYAPKLDSPYFRHSSVSFFPS FPPAIPGLPTLLPHPGPFGSLQGAFQPKVSDPYRAVVKVSTCWEGPWQGRTLVPPGRPRGARDSRSLQKTWVGVAPAPLSASILSQKPGR WCAVHVQIAWQIYRHQQKIKEMQLDPHKLEVGAKLDLFGRPPAPGVFAGFHYPQDLARPLFPSTGAAHPASNPFGPSAHPGSFLPTGPLT DPFSRPSTFGGLGSLSSHAFGGLGSHALAPGGSIFAPKEGSSVHGLPSPHEAWNRLHRAPPSFPAPPPWPKSVDAERVSALTNHDREPDN GKEEQERDLLEKTRLLSRASPATPAGHPVSGLLLRAQSELGRSGAPAEREAEPRVKESRSPAKEEAAKMPARASPPHSKAAPGDVKVKEE RGEDEASEPPAGGLHPAPLQLGLGRERLGAPGFAWEPFRGLELPRRAFPAAAPAPGSAALLEPPERPYRDREPHGYSPERLRGELERARA PHLPPAAPALDGALLPSLGALHFPRLSPAALHNGLLARTPPAAAALGAPPPLVTAAGPPTPPGPPRSRTTPLGGLGPGEARDYSPSRNPP -------------------------------------------------------------- >63925_63925_5_PDIA6-FBRSL1_PDIA6_chr2_10933222_ENST00000404824_FBRSL1_chr12_133102320_ENST00000261673_length(transcript)=3618nt_BP=969nt AGAACCCCTCAGGGCCTCAGCTGAAGCTCAGACAGAGTGCCTGCGTGCGCGCGCACACACACACACACACACACACACAACCTAATTTTC AACACACTTGCACAAATATAGAAACATCATGGGGAAAAATGCAAAATACCTATGATTTCTGGAACAAGATCCAAGATGACAAAGATATTC CCTGCTTATTCTGCTCATGCCCGGGCTCCCCTGCCCACCCCCAGTGCGTTCATGTGATATCATGAAAAAGCAGCAGGGGTGGCATGAACT TGCACACCAGGCTGCCCAGGCTTGAGACCCAGCTCTGCCACCTAGAAGCTTGGAGCCCCTGAACAAGCTGCAATTCTGTGCCTGGGCTTT TCTGACTGCAAAATGAGGATAATCACAGCCCCTGCCTCCAAAGTGTCCCGAGGATCAAATGAGTTGATGATACTTGCACGGCGCTCGGAT CGTGGCTCACCAACTTCTCCTGCCCACTCCCTATCAAGGAAAAGTCCCATAATGTATCCATCAACCACCATGGCTAATGCACCCGGTCTG GTGAGCTGTACCTTCTTTCTGGCAGTGAATGGTCTGTATTCCTCTAGTGATGATGTGATCGAATTAACTCCATCGAATTTCAACCGAGAA GTTATTCAGAGTGATAGTTTGTGGCTTGTAGAATTCTATGCTCCATGGTGTGGTCACTGTCAAAGATTAACACCAGAATGGAAGAAAGCA GCAACTGCATTAAAAGATGTTGTCAAAGTTGGTGCAGTTGATGCAGATAAGCATCATTCCCTAGGAGGTCAGTATGGTGTTCAGGGATTT CCTACCATTAAGATTTTTGGATCCAACAAAAACAGACCAGAAGATTACCAAGGTGGCAGAACTGGTGAAGCCATTGTAGATGCTGCGCTG AGTGCTCTGCGCCAGCTCGTGAAGGATCGCCTCGGGGGACGGAGCGGAGGATACAGTTCTGGAAAACAAATGAAGGTCACCGTGTCCAAA GGGGGCGACCGGGACAGTGACGACGACAGCGTCCTCGAAGCCACCAGCTCCCGGGACCCGCTCAGCGATAGCTCTGCGCATGCGGTCTCG GGGAGAGGCTACTCTTGTGACAGCGAGAGCGGCCCGGACGACAAGGCATCCGTGGGCTCTGAGAAGCTCTTTGCGCCGGGAACCGATAAA GGCCCAGCGCTTGAGAAGTCGGAGGCCAAGGCCGGGCCGGTGCCCAAGGTGTCAGGCCTGGAGCGCAGCCGCGAGCTCAGCGCCGAGAGC TTCCTGCCCACTGCCAGCCCCGCGCCCCATGCCGCGCCCTGCCCGGGGCCCCCGCCCGGCTCCCGCGCCAATCCCTTGGTGAAGAAGGAA CCCCCCGCCCCGCACCGCCACACCCCGCAGCCGCCACCCCCGCAGCCCCGCGGCCTGCTCCCGACACACGTGCCTGCATCCCTGGGCGCC TTCGCGGGCCACAGCCAGGCGGCAGCCAACGGCCTGCACGGCCTCAGCAGGAGCAGCAGCGCCCCCCTGGGCCTGGGGAAGCACGTGTCG CTGTCGCCACACGGGCCGGGCCCCCACCTGTCTACCTCACACCTGGCGCTCCGGTCCCAGGCGCAGCACCAGCTCCACGCGGCCATGTTT GCCGCACCCCCGACACTGCCCCCGCCCCCGGCGCTGCCGGCCAGCAGCCTGGTCCTCCCAGGACACCCGGCCGATCACGAGCTGCTCAGG CAAGAGCTGAACACGCGGTTTCTGGTGCAGAGCGCCGAGCGGCCTGGCGCCTCCCTGGGCCCGGGGGCTCTGCTGCGGGCGGAGTTCCAT CAGCACCAGCACACACACCAGCACACGCACCAACACACACACCAGCACCAACACACATTCGCCCCCTTCCCCGCAGGGCTGCCCCCGACG CCGCCCGCCGCACCCCCGCCGTTTGACAAGTATGCGCCCAAGCTGGACAGCCCCTACTTCCGACATTCCAGCGTGAGTTTCTTCCCGTCC TTCCCTCCTGCCATCCCGGGACTGCCCACCCTGCTCCCACACCCCGGCCCCTTCGGGTCCCTGCAGGGCGCTTTTCAGCCTAAGGTGTCT GACCCGTACCGGGCGGTGGTCAAGGTGAGCACGTGTTGGGAAGGCCCGTGGCAAGGGAGGACTCTGGTGCCCCCGGGGCGGCCTCGGGGG GCCCGTGACAGCAGGAGTCTGCAGAAAACATGGGTGGGGGTGGCACCAGCCCCACTGAGCGCTTCCATCCTGTCGCAGAAGCCGGGGAGG TGGTGTGCCGTGCACGTGCAGATCGCCTGGCAGATCTACCGTCACCAGCAGAAGATAAAGGAGATGCAGCTGGACCCCCACAAGCTGGAG GTGGGTGCAAAGCTGGACCTGTTCGGCAGACCCCCTGCCCCGGGCGTGTTTGCAGGCTTCCACTACCCACAGGACCTGGCCCGGCCCCTC TTCCCCAGCACAGGTGCCGCCCATCCTGCCTCCAACCCATTTGGACCCTCAGCCCATCCTGGCAGCTTCCTGCCCACTGGCCCCCTGACA GACCCTTTCAGCAGACCGAGCACCTTTGGGGGCCTGGGCAGCCTGAGCAGCCACGCCTTTGGGGGCCTGGGCAGCCATGCACTGGCTCCC GGTGGCAGCATCTTTGCCCCCAAGGAGGGCTCCTCCGTGCACGGCCTGCCCAGCCCCCATGAGGCCTGGAACCGACTGCACCGGGCACCG CCCTCCTTCCCGGCTCCGCCCCCGTGGCCCAAGTCCGTGGACGCGGAGCGGGTGTCAGCCCTGACCAACCATGACCGAGAGCCGGACAAT GGCAAGGAGGAGCAGGAACGGGACCTCCTGGAGAAGACGCGCCTGCTGAGCCGGGCCTCGCCCGCCACCCCCGCTGGCCACCCCGTCAGC GGCCTCCTGCTCCGGGCCCAGAGCGAGCTGGGCCGGTCCGGGGCCCCCGCGGAGCGCGAGGCCGAACCTCGGGTCAAGGAGAGCCGCTCC CCGGCCAAGGAGGAGGCCGCCAAGATGCCCGCGCGCGCATCCCCGCCCCACAGCAAGGCGGCCCCTGGAGACGTGAAGGTCAAGGAGGAG CGCGGGGAGGACGAGGCCTCCGAGCCCCCGGCGGGCGGCCTGCACCCCGCGCCCCTGCAGCTCGGCCTGGGCCGCGAGCGCCTGGGCGCG CCGGGCTTCGCGTGGGAGCCTTTCCGCGGCCTGGAGCTGCCACGTCGCGCCTTCCCCGCTGCCGCCCCCGCCCCGGGCTCCGCCGCCCTC TTGGAGCCCCCGGAGCGCCCCTACCGCGACCGCGAGCCCCACGGCTACAGCCCCGAGCGCCTGCGCGGGGAGCTGGAGCGCGCGCGGGCC CCGCACCTGCCGCCCGCCGCCCCCGCCTTGGACGGCGCGCTGCTGCCCTCGCTGGGAGCCCTGCACTTCCCGCGCCTCTCGCCCGCCGCG CTGCACAATGGGCTCCTGGCGCGGACCCCGCCCGCCGCCGCCGCCCTCGGCGCACCGCCCCCCCTGGTGACGGCGGCCGGGCCCCCCACG CCCCCCGGGCCGCCGCGGAGCCGGACTACTCCGCTGGGGGGCCTCGGGCCGGGCGAGGCGCGCGACTACTCCCCGTCCCGAAATCCCCCG >63925_63925_5_PDIA6-FBRSL1_PDIA6_chr2_10933222_ENST00000404824_FBRSL1_chr12_133102320_ENST00000261673_length(amino acids)=1090AA_BP=207 MCLGFSDCKMRIITAPASKVSRGSNELMILARRSDRGSPTSPAHSLSRKSPIMYPSTTMANAPGLVSCTFFLAVNGLYSSSDDVIELTPS NFNREVIQSDSLWLVEFYAPWCGHCQRLTPEWKKAATALKDVVKVGAVDADKHHSLGGQYGVQGFPTIKIFGSNKNRPEDYQGGRTGEAI VDAALSALRQLVKDRLGGRSGGYSSGKQMKVTVSKGGDRDSDDDSVLEATSSRDPLSDSSAHAVSGRGYSCDSESGPDDKASVGSEKLFA PGTDKGPALEKSEAKAGPVPKVSGLERSRELSAESFLPTASPAPHAAPCPGPPPGSRANPLVKKEPPAPHRHTPQPPPPQPRGLLPTHVP ASLGAFAGHSQAAANGLHGLSRSSSAPLGLGKHVSLSPHGPGPHLSTSHLALRSQAQHQLHAAMFAAPPTLPPPPALPASSLVLPGHPAD HELLRQELNTRFLVQSAERPGASLGPGALLRAEFHQHQHTHQHTHQHTHQHQHTFAPFPAGLPPTPPAAPPPFDKYAPKLDSPYFRHSSV SFFPSFPPAIPGLPTLLPHPGPFGSLQGAFQPKVSDPYRAVVKVSTCWEGPWQGRTLVPPGRPRGARDSRSLQKTWVGVAPAPLSASILS QKPGRWCAVHVQIAWQIYRHQQKIKEMQLDPHKLEVGAKLDLFGRPPAPGVFAGFHYPQDLARPLFPSTGAAHPASNPFGPSAHPGSFLP TGPLTDPFSRPSTFGGLGSLSSHAFGGLGSHALAPGGSIFAPKEGSSVHGLPSPHEAWNRLHRAPPSFPAPPPWPKSVDAERVSALTNHD REPDNGKEEQERDLLEKTRLLSRASPATPAGHPVSGLLLRAQSELGRSGAPAEREAEPRVKESRSPAKEEAAKMPARASPPHSKAAPGDV KVKEERGEDEASEPPAGGLHPAPLQLGLGRERLGAPGFAWEPFRGLELPRRAFPAAAPAPGSAALLEPPERPYRDREPHGYSPERLRGEL ERARAPHLPPAAPALDGALLPSLGALHFPRLSPAALHNGLLARTPPAAAALGAPPPLVTAAGPPTPPGPPRSRTTPLGGLGPGEARDYSP -------------------------------------------------------------- >63925_63925_6_PDIA6-FBRSL1_PDIA6_chr2_10933222_ENST00000404824_FBRSL1_chr12_133102320_ENST00000434748_length(transcript)=5028nt_BP=969nt AGAACCCCTCAGGGCCTCAGCTGAAGCTCAGACAGAGTGCCTGCGTGCGCGCGCACACACACACACACACACACACACAACCTAATTTTC AACACACTTGCACAAATATAGAAACATCATGGGGAAAAATGCAAAATACCTATGATTTCTGGAACAAGATCCAAGATGACAAAGATATTC CCTGCTTATTCTGCTCATGCCCGGGCTCCCCTGCCCACCCCCAGTGCGTTCATGTGATATCATGAAAAAGCAGCAGGGGTGGCATGAACT TGCACACCAGGCTGCCCAGGCTTGAGACCCAGCTCTGCCACCTAGAAGCTTGGAGCCCCTGAACAAGCTGCAATTCTGTGCCTGGGCTTT TCTGACTGCAAAATGAGGATAATCACAGCCCCTGCCTCCAAAGTGTCCCGAGGATCAAATGAGTTGATGATACTTGCACGGCGCTCGGAT CGTGGCTCACCAACTTCTCCTGCCCACTCCCTATCAAGGAAAAGTCCCATAATGTATCCATCAACCACCATGGCTAATGCACCCGGTCTG GTGAGCTGTACCTTCTTTCTGGCAGTGAATGGTCTGTATTCCTCTAGTGATGATGTGATCGAATTAACTCCATCGAATTTCAACCGAGAA GTTATTCAGAGTGATAGTTTGTGGCTTGTAGAATTCTATGCTCCATGGTGTGGTCACTGTCAAAGATTAACACCAGAATGGAAGAAAGCA GCAACTGCATTAAAAGATGTTGTCAAAGTTGGTGCAGTTGATGCAGATAAGCATCATTCCCTAGGAGGTCAGTATGGTGTTCAGGGATTT CCTACCATTAAGATTTTTGGATCCAACAAAAACAGACCAGAAGATTACCAAGGTGGCAGAACTGGTGAAGCCATTGTAGATGCTGCGCTG AGTGCTCTGCGCCAGCTCGTGAAGGATCGCCTCGGGGGACGGAGCGGAGGATACAGTTCTGGAAAACAAATGAAGGTCACCGTGTCCAAA GGGGGCGACCGGGACAGTGACGACGACAGCGTCCTCGAAGCCACCAGCTCCCGGGACCCGCTCAGCGATAGCTCTGCGCATGCGGTCTCG GGGAGAGGCTACTCTTGTGACAGCGAGAGCGGCCCGGACGACAAGGCATCCGTGGGCTCTGAGAAGCTCTTTGCGCCGGGAACCGATAAA GGCCCAGCGCTTGAGAAGTCGGAGGCCAAGGCCGGGCCGGTGCCCAAGGTGTCAGGCCTGGAGCGCAGCCGCGAGCTCAGCGCCGAGAGC TTCCTGCCCACTGCCAGCCCCGCGCCCCATGCCGCGCCCTGCCCGGGGCCCCCGCCCGGCTCCCGCGCCAATCCCTTGGTGAAGAAGGAA CCCCCCGCCCCGCACCGCCACACCCCGCAGCCGCCACCCCCGCAGCCCCGCGGCCTGCTCCCGACACACGTGCCTGCATCCCTGGGCGCC TTCGCGGGCCACAGCCAGGCGGCAGCCAACGGCCTGCACGGCCTCAGCAGGAGCAGCAGCGCCCCCCTGGGCCTGGGGAAGCACGTGTCG CTGTCGCCACACGGGCCGGGCCCCCACCTGTCTACCTCACACCTGGCGCTCCGGTCCCAGGCGCAGCACCAGCTCCACGCGGCCATGTTT GCCGCACCCCCGACACTGCCCCCGCCCCCGGCGCTGCCGGCCAGCAGCCTGGTCCTCCCAGGACACCCGGCCGATCACGAGCTGCTCAGG CAAGAGCTGAACACGCGGTTTCTGGTGCAGAGCGCCGAGCGGCCTGGCGCCTCCCTGGGCCCGGGGGCTCTGCTGCGGGCGGAGTTCCAT CAGCACCAGCACACACACCAGCACACGCACCAACACACACACCAGCACCAACACACATTCGCCCCCTTCCCCGCAGGGCTGCCCCCGACG CCGCCCGCCGCACCCCCGCCGTTTGACAAGTATGCGCCCAAGCTGGACAGCCCCTACTTCCGACATTCCAGCGTGAGTTTCTTCCCGTCC TTCCCTCCTGCCATCCCGGGACTGCCCACCCTGCTCCCACACCCCGGCCCCTTCGGGTCCCTGCAGGGCGCTTTTCAGCCTAAGGTGTCT GACCCGTACCGGGCGGTGGTCAAGGTGAGCACGTGTTGGGAAGGCCCGTGGCAAGGGAGGACTCTGGTGCCCCCGGGGCGGCCTCGGGGG GCCCGTGACAGCAGGAGTCTGCAGAAAACATGGGTGGGGGTGGCACCAGCCCCACTGAGCGCTTCCATCCTGTCGCAGAAGCCGGGGAGG TGGTGTGCCGTGCACGTGCAGATCGCCTGGCAGATCTACCGTCACCAGCAGAAGATAAAGGAGATGCAGCTGGACCCCCACAAGCTGGAG GTGGGTGCAAAGCTGGACCTGTTCGGCAGACCCCCTGCCCCGGGCGTGTTTGCAGGCTTCCACTACCCACAGGACCTGGCCCGGCCCCTC TTCCCCAGCACAGGTGCCGCCCATCCTGCCTCCAACCCATTTGGACCCTCAGCCCATCCTGGCAGCTTCCTGCCCACTGGCCCCCTGACA GACCCTTTCAGCAGACCGAGCACCTTTGGGGGCCTGGGCAGCCTGAGCAGCCACGCCTTTGGGGGCCTGGGCAGCCATGCACTGGCTCCC GGTGGCAGCATCTTTGCCCCCAAGGAGGGCTCCTCCGTGCACGGCCTGCCCAGCCCCCATGAGGCCTGGAACCGACTGCACCGGGCACCG CCCTCCTTCCCGGCTCCGCCCCCGTGGCCCAAGTCCGTGGACGCGGAGCGGGTGTCAGCCCTGACCAACCATGACCGAGAGCCGGACAAT GGCAAGGAGGAGCAGGAACGGGACCTCCTGGAGAAGACGCGCCTGCTGAGCCGGGCCTCGCCCGCCACCCCCGCTGGCCACCCCGTCAGC GGCCTCCTGCTCCGGGCCCAGAGCGAGCTGGGCCGGTCCGGGGCCCCCGCGGAGCGCGAGGCCGAACCTCGGGTCAAGGAGAGCCGCTCC CCGGCCAAGGAGGAGGCCGCCAAGATGCCCGCGCGCGCATCCCCGCCCCACAGCAAGGCGGCCCCTGGAGACGTGAAGGTCAAGGAGGAG CGCGGGGAGGACGAGGCCTCCGAGCCCCCGGCGGGCGGCCTGCACCCCGCGCCCCTGCAGCTCGGCCTGGGCCGCGAGCGCCTGGGCGCG CCGGGCTTCGCGTGGGAGCCTTTCCGCGGCCTGGAGCTGCCACGTCGCGCCTTCCCCGCTGCCGCCCCCGCCCCGGGCTCCGCCGCCCTC TTGGAGCCCCCGGAGCGCCCCTACCGCGACCGCGAGCCCCACGGCTACAGCCCCGAGCGCCTGCGCGGGGAGCTGGAGCGCGCGCGGGCC CCGCACCTGCCGCCCGCCGCCCCCGCCTTGGACGGCGCGCTGCTGCCCTCGCTGGGAGCCCTGCACTTCCCGCGCCTCTCGCCCGCCGCG CTGCACAATGGGCTCCTGGCGCGGACCCCGCCCGCCGCCGCCGCCCTCGGCGCACCGCCCCCCCTGGTGACGGCGGCCGGGCCCCCCACG CCCCCCGGGCCGCCGCGGAGCCGGACTACTCCGCTGGGGGGCCTCGGGCCGGGCGAGGCGCGCGACTACTCCCCGTCCCGAAATCCCCCG GAGGTGGAGGCGCGGTAGCCCCGGGGCCGCAGACGCCTCTCCGAGCGGAGCGCACCGCTGTCCGTCTCTCCATCAGTTCCTAGAACTCAA GCACAGCTCCCGCCGATCCTGGGGCGGCGCCGCCTCTCCACCCGCAGCCTGCGGAGGCGGGGACTTGGGTGTCGGCTTTTCTGAGGGTGA TCTTTTGTTTTCCGAGTTTGGGATTCGGCTGTTGGGAAAAAAAAATCGCGTTTGTACCTTTTCCCCCCACAGATGAGAAGTGTTTGTAAT GGATTTGTATTTTTCTTAATTTTATGCTCTTTAGACGTTTAAAAGAACCAAAAAAGAAACTTTTGCTTCTTCGTTTTCGGTTGGGATTTG CAGTTTAATGGCCTCAGATCCTTCTCCAGATCCCCAGGGTTTCTTTGTCTTATTTATGGAGAAAAACCGGTCACTTTGTCCAGCGCACTG TGAGGCCCCCACTCAGGCCAGCCCTGGCCCCCCCTTGGTACTTGGAACCGAAGTTACAGATTATATTAAAATAATAATGTACAAAACTTT GTTTTTTTGCCTTATTATGCAGAAGTGTAATTTCTTTTTTGGTTTGTTTTTTTAAAAGCAAACGAAACGTGTAAATAGTCTGTTGATATA AATATATGACGTTACTAAATTCTTAATCTAGATAGACTTTATAAAAACCGTTTCCAGAAACCCCTCTGGTTGTTTGTCTAACATGGTCAC AAAAACCCAGGCGCTGCTGGCTGTAAACATTATCAGAAGTTTAATGGCAGCAACTTTCCTTCAACTATGCAAGCGCTTCCCGGCGGCTCT GCTGGTTGGGGGAGGAAGGTTCCGCCAGCGACCTCCCAGCCCCTGGGTCCGTGGAGGGGTTGGGTCCCCCAGCAGAGCCCCTGGGCCAGC AGAACAGCACTCCTGGGCGGCTCCTGTGGGCTTCAGGACTGGCCGGCTCCAGCCGCAAGGGCGATGCTGTGGACGTTTGTGTGGATGGTG CAGTGTTCTTGGAATCTGTAGACCAGATCGGTGGAGGTATAGAAGTGCAAGAGTCTAAAGGCTGATTTTACACACACACACACACACACA CACACACACACAAAATCACTGCTGTGTGTTTTCTTCCGCCTGAGGCATCAGCGTCACCTCGGTGTGGTCGTCGCCTCCCAGGCCCTTGGC CTGGCCTCCTCTCAGTTTGGGTTTTGCCCTCACCCACATGAGCCCCCCCATGCCCTGCCCCCCTTGCGGCCTTTTGTGTTCCCCGATGTC TGGGCTGTGTCCCTGCCGGGATTCCCAGCCTTCGGGGTCAGCCGTCGAGCCACTTGCTTTGCTCAGTTCTGTGTTTCAGCCACATTTCCA >63925_63925_6_PDIA6-FBRSL1_PDIA6_chr2_10933222_ENST00000404824_FBRSL1_chr12_133102320_ENST00000434748_length(amino acids)=1090AA_BP=207 MCLGFSDCKMRIITAPASKVSRGSNELMILARRSDRGSPTSPAHSLSRKSPIMYPSTTMANAPGLVSCTFFLAVNGLYSSSDDVIELTPS NFNREVIQSDSLWLVEFYAPWCGHCQRLTPEWKKAATALKDVVKVGAVDADKHHSLGGQYGVQGFPTIKIFGSNKNRPEDYQGGRTGEAI VDAALSALRQLVKDRLGGRSGGYSSGKQMKVTVSKGGDRDSDDDSVLEATSSRDPLSDSSAHAVSGRGYSCDSESGPDDKASVGSEKLFA PGTDKGPALEKSEAKAGPVPKVSGLERSRELSAESFLPTASPAPHAAPCPGPPPGSRANPLVKKEPPAPHRHTPQPPPPQPRGLLPTHVP ASLGAFAGHSQAAANGLHGLSRSSSAPLGLGKHVSLSPHGPGPHLSTSHLALRSQAQHQLHAAMFAAPPTLPPPPALPASSLVLPGHPAD HELLRQELNTRFLVQSAERPGASLGPGALLRAEFHQHQHTHQHTHQHTHQHQHTFAPFPAGLPPTPPAAPPPFDKYAPKLDSPYFRHSSV SFFPSFPPAIPGLPTLLPHPGPFGSLQGAFQPKVSDPYRAVVKVSTCWEGPWQGRTLVPPGRPRGARDSRSLQKTWVGVAPAPLSASILS QKPGRWCAVHVQIAWQIYRHQQKIKEMQLDPHKLEVGAKLDLFGRPPAPGVFAGFHYPQDLARPLFPSTGAAHPASNPFGPSAHPGSFLP TGPLTDPFSRPSTFGGLGSLSSHAFGGLGSHALAPGGSIFAPKEGSSVHGLPSPHEAWNRLHRAPPSFPAPPPWPKSVDAERVSALTNHD REPDNGKEEQERDLLEKTRLLSRASPATPAGHPVSGLLLRAQSELGRSGAPAEREAEPRVKESRSPAKEEAAKMPARASPPHSKAAPGDV KVKEERGEDEASEPPAGGLHPAPLQLGLGRERLGAPGFAWEPFRGLELPRRAFPAAAPAPGSAALLEPPERPYRDREPHGYSPERLRGEL ERARAPHLPPAAPALDGALLPSLGALHFPRLSPAALHNGLLARTPPAAAALGAPPPLVTAAGPPTPPGPPRSRTTPLGGLGPGEARDYSP -------------------------------------------------------------- |
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Fusion Gene PPI Analysis for PDIA6-FBRSL1 |
| Go to ChiPPI (Chimeric Protein-Protein interactions) to see the chimeric PPI interaction in |
| Protein-protein interactors with each fusion partner protein in wild-type (BIOGRID-3.4.160) |
| Hgene | Hgene's interactors | Tgene | Tgene's interactors |
| - Retained PPIs in in-frame fusion. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Still interaction with |
| - Lost PPIs in in-frame fusion. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Interaction lost with |
| - Retained PPIs, but lost function due to frame-shift fusion. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Interaction lost with |
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Related Drugs for PDIA6-FBRSL1 |
| Drugs targeting genes involved in this fusion gene. (DrugBank Version 5.1.8 2021-05-08) |
| Partner | Gene | UniProtAcc | DrugBank ID | Drug name | Drug activity | Drug type | Drug status |
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Related Diseases for PDIA6-FBRSL1 |
| Diseases associated with fusion partners. (DisGeNet 4.0) |
| Partner | Gene | Disease ID | Disease name | # pubmeds | Source |
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