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Center for Computational Systems Medicine
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Fusion Gene Summary

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Fusion Gene ORF analysis

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Fusion Genomic Features

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Fusion Protein Features

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Fusion Gene Sequence

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Fusion Gene PPI analysis

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Related Drugs

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Related Diseases

Fusion gene:PDLIM7-ZMIZ1 (FusionGDB2 ID:64017)

Fusion Gene Summary for PDLIM7-ZMIZ1

check button Fusion gene summary
Fusion gene informationFusion gene name: PDLIM7-ZMIZ1
Fusion gene ID: 64017
HgeneTgene
Gene symbol

PDLIM7

ZMIZ1

Gene ID

9260

57178

Gene namePDZ and LIM domain 7zinc finger MIZ-type containing 1
SynonymsLMP1|LMP3MIZ|NEDDFSA|RAI17|TRAFIP10|ZIMP10
Cytomap

5q35.3

10q22.3

Type of geneprotein-codingprotein-coding
DescriptionPDZ and LIM domain protein 71110003B01RikLIM domain proteinLMPLim mineralization protein 3PDZ and LIM domain 7 (enigma)protein enigmazinc finger MIZ domain-containing protein 1retinoic acid induced 17zinc finger-containing, Miz1, PIAS-like protein on chromosome 10
Modification date2020032720200315
UniProtAcc..
Ensembl transtripts involved in fusion geneENST00000355572, ENST00000355841, 
ENST00000356618, ENST00000359895, 
ENST00000393551, ENST00000505746, 
ENST00000446377, ENST00000478357, 
ENST00000334512, 
Fusion gene scores* DoF score6 X 7 X 3=1267 X 8 X 5=280
# samples 78
** MAII scorelog2(7/126*10)=-0.84799690655495
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0		log2(8/280*10)=-1.8073549220576
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0
Context

PubMed: PDLIM7 [Title/Abstract] AND ZMIZ1 [Title/Abstract] AND fusion [Title/Abstract]

Most frequent breakpointPDLIM7(176919406)-ZMIZ1(81072399), # samples:1
Anticipated loss of major functional domain due to fusion event.PDLIM7-ZMIZ1 seems lost the major protein functional domain in Hgene partner, which is a essential gene due to the frame-shifted ORF.
PDLIM7-ZMIZ1 seems lost the major protein functional domain in Tgene partner, which is a essential gene due to the frame-shifted ORF.
* DoF score (Degree of Frequency) = # partners X # break points X # cancer types
** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10)

check button Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez
PartnerGeneGO IDGO termPubMed ID
TgeneZMIZ1

GO:0007179

transforming growth factor beta receptor signaling pathway

16777850

TgeneZMIZ1

GO:0030521

androgen receptor signaling pathway

14609956

TgeneZMIZ1

GO:0033233

regulation of protein sumoylation

14609956

TgeneZMIZ1

GO:0045944

positive regulation of transcription by RNA polymerase II

26522984

TgeneZMIZ1

GO:0060395

SMAD protein signal transduction

16777850

TgeneZMIZ1

GO:1903508

positive regulation of nucleic acid-templated transcription

14609956|16777850


check buttonFusion gene breakpoints across PDLIM7 (5'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.
all structure

check buttonFusion gene breakpoints across ZMIZ1 (3'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.
all structure

check button Fusion gene information from two resources (ChiTars 5.0 and ChimerDB 4.0)
* All genome coordinats were lifted-over on hg19.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
SourceDiseaseSampleHgeneHchrHbpHstrandTgeneTchrTbpTstrand
ChimerDB4STADTCGA-FP-8210-01APDLIM7chr5

176919406

-ZMIZ1chr10

81072399

+


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Fusion Gene ORF analysis for PDLIM7-ZMIZ1

check button Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
ORFHenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrand
5CDS-intronENST00000355572ENST00000446377PDLIM7chr5

176919406

-ZMIZ1chr10

81072399

+
5CDS-intronENST00000355572ENST00000478357PDLIM7chr5

176919406

-ZMIZ1chr10

81072399

+
5CDS-intronENST00000355841ENST00000446377PDLIM7chr5

176919406

-ZMIZ1chr10

81072399

+
5CDS-intronENST00000355841ENST00000478357PDLIM7chr5

176919406

-ZMIZ1chr10

81072399

+
5CDS-intronENST00000356618ENST00000446377PDLIM7chr5

176919406

-ZMIZ1chr10

81072399

+
5CDS-intronENST00000356618ENST00000478357PDLIM7chr5

176919406

-ZMIZ1chr10

81072399

+
5CDS-intronENST00000359895ENST00000446377PDLIM7chr5

176919406

-ZMIZ1chr10

81072399

+
5CDS-intronENST00000359895ENST00000478357PDLIM7chr5

176919406

-ZMIZ1chr10

81072399

+
5CDS-intronENST00000393551ENST00000446377PDLIM7chr5

176919406

-ZMIZ1chr10

81072399

+
5CDS-intronENST00000393551ENST00000478357PDLIM7chr5

176919406

-ZMIZ1chr10

81072399

+
Frame-shiftENST00000356618ENST00000334512PDLIM7chr5

176919406

-ZMIZ1chr10

81072399

+
In-frameENST00000355572ENST00000334512PDLIM7chr5

176919406

-ZMIZ1chr10

81072399

+
In-frameENST00000355841ENST00000334512PDLIM7chr5

176919406

-ZMIZ1chr10

81072399

+
In-frameENST00000359895ENST00000334512PDLIM7chr5

176919406

-ZMIZ1chr10

81072399

+
In-frameENST00000393551ENST00000334512PDLIM7chr5

176919406

-ZMIZ1chr10

81072399

+
intron-3CDSENST00000505746ENST00000334512PDLIM7chr5

176919406

-ZMIZ1chr10

81072399

+
intron-intronENST00000505746ENST00000446377PDLIM7chr5

176919406

-ZMIZ1chr10

81072399

+
intron-intronENST00000505746ENST00000478357PDLIM7chr5

176919406

-ZMIZ1chr10

81072399

+

check buttonORFfinder result based on the fusion transcript sequence of in-frame fusion genes.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandSeq length
(transcript)		BP loci
(transcript)		Predicted start
(transcript)		Predicted stop
(transcript)		Seq length
(amino acids)
ENST00000359895PDLIM7chr5176919406-ENST00000334512ZMIZ1chr1081072399+420232411001921273
ENST00000355841PDLIM7chr5176919406-ENST00000334512ZMIZ1chr1081072399+422434611221943273
ENST00000393551PDLIM7chr5176919406-ENST00000334512ZMIZ1chr1081072399+422434611221943273
ENST00000355572PDLIM7chr5176919406-ENST00000334512ZMIZ1chr1081072399+421433611121933273

check buttonDeepORF prediction of the coding potential based on the fusion transcript sequence of in-frame fusion genes. DeepORF is a coding potential classifier based on convolutional neural network by comparing the real Ribo-seq data. If the no-coding score < 0.5 and coding score > 0.5, then the in-frame fusion transcript is predicted as being likely translated.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandNo-coding scoreCoding score
ENST00000359895ENST00000334512PDLIM7chr5176919406-ZMIZ1chr1081072399+0.767019870.2329801
ENST00000355841ENST00000334512PDLIM7chr5176919406-ZMIZ1chr1081072399+0.77445460.22554538
ENST00000393551ENST00000334512PDLIM7chr5176919406-ZMIZ1chr1081072399+0.77445460.22554538
ENST00000355572ENST00000334512PDLIM7chr5176919406-ZMIZ1chr1081072399+0.7738170.22618298

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Fusion Genomic Features for PDLIM7-ZMIZ1


check buttonFusionAI prediction of the potential fusion gene breakpoint based on the pre-mature RNA sequence context (+/- 5kb of individual partner genes, total 20kb length sequence). FusionAI is a fusion gene breakpoint classifier based on convolutional neural network by comparing the fusion positive and negative sequence context of ~ 20K fusion gene data. From here, we can have the relative potentency of the 20K genomic sequence how individual sequnce will be likely used as the gene fusion breakpoints.
HgeneHchrHbpHstrandTgeneTchrTbpTstrand1-pp (fusion gene breakpoint)
PDLIM7chr5176919405-ZMIZ1chr1081072398+0.789130870.21086916
PDLIM7chr5176919405-ZMIZ1chr1081072398+0.789130870.21086916

check buttonDistribution of 44 human genomic features loci across 20kb length fusion breakpoint regions. We integrated a total of 44 different types of human genomic feature loci information across five big categories including virus integration sites, repeats, structural variants, chromatin states, and gene expression regulation. More details are in help page.
genomic feature

check buttonDistribution of 44 human genomic features loci across 20kb length fusion breakpoint regions that are ovelapped with the top 1% feature importance score regions. More details are in help page.
genomic feature of top 1%

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Fusion Protein Features for PDLIM7-ZMIZ1


check button Four levels of functional features of fusion genes
Go to FGviewer search page for the most frequent breakpoint (https://ccsmweb.uth.edu/FGviewer/chr5:176919406/chr10:81072399)
- FGviewer provides the online visualization of the retention search of the protein functional features across DNA, RNA, protein, and pathological levels.
- How to search
1. Put your fusion gene symbol.
2. Press the tab key until there will be shown the breakpoint information filled.
4. Go down and press 'Search' tab twice.
4. Go down to have the hyperlink of the search result.
5. Click the hyperlink.
6. See the FGviewer result for your fusion gene.
FGviewer

check buttonMain function of each fusion partner protein. (from UniProt)
HgeneTgene
..
FUNCTION: Transcriptional activator which is required for calcium-dependent dendritic growth and branching in cortical neurons. Recruits CREB-binding protein (CREBBP) to nuclear bodies. Component of the CREST-BRG1 complex, a multiprotein complex that regulates promoter activation by orchestrating a calcium-dependent release of a repressor complex and a recruitment of an activator complex. In resting neurons, transcription of the c-FOS promoter is inhibited by BRG1-dependent recruitment of a phospho-RB1-HDAC1 repressor complex. Upon calcium influx, RB1 is dephosphorylated by calcineurin, which leads to release of the repressor complex. At the same time, there is increased recruitment of CREBBP to the promoter by a CREST-dependent mechanism, which leads to transcriptional activation. The CREST-BRG1 complex also binds to the NR2B promoter, and activity-dependent induction of NR2B expression involves a release of HDAC1 and recruitment of CREBBP (By similarity). {ECO:0000250}.FUNCTION: Transcriptional activator which is required for calcium-dependent dendritic growth and branching in cortical neurons. Recruits CREB-binding protein (CREBBP) to nuclear bodies. Component of the CREST-BRG1 complex, a multiprotein complex that regulates promoter activation by orchestrating a calcium-dependent release of a repressor complex and a recruitment of an activator complex. In resting neurons, transcription of the c-FOS promoter is inhibited by BRG1-dependent recruitment of a phospho-RB1-HDAC1 repressor complex. Upon calcium influx, RB1 is dephosphorylated by calcineurin, which leads to release of the repressor complex. At the same time, there is increased recruitment of CREBBP to the promoter by a CREST-dependent mechanism, which leads to transcriptional activation. The CREST-BRG1 complex also binds to the NR2B promoter, and activity-dependent induction of NR2B expression involves a release of HDAC1 and recruitment of CREBBP (By similarity). {ECO:0000250}.

check buttonRetention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at

download page


* Minus value of BPloci means that the break pointn is located before the CDS.
- In-frame and retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
HgenePDLIM7chr5:176919406chr10:81072399ENST00000355572-481_8593223.0DomainPDZ
HgenePDLIM7chr5:176919406chr10:81072399ENST00000355841-4131_8593458.0DomainPDZ
HgenePDLIM7chr5:176919406chr10:81072399ENST00000356618-4121_8593418.3333333333333DomainPDZ
HgenePDLIM7chr5:176919406chr10:81072399ENST00000359895-4131_8593424.0DomainPDZ
HgenePDLIM7chr5:176919406chr10:81072399ENST00000393551-491_8593288.0DomainPDZ

- In-frame and not-retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
HgenePDLIM7chr5:176919406chr10:81072399ENST00000355572-48280_33893223.0DomainLIM zinc-binding 1
HgenePDLIM7chr5:176919406chr10:81072399ENST00000355572-48339_39893223.0DomainLIM zinc-binding 2
HgenePDLIM7chr5:176919406chr10:81072399ENST00000355572-48399_45793223.0DomainLIM zinc-binding 3
HgenePDLIM7chr5:176919406chr10:81072399ENST00000355841-413280_33893458.0DomainLIM zinc-binding 1
HgenePDLIM7chr5:176919406chr10:81072399ENST00000355841-413339_39893458.0DomainLIM zinc-binding 2
HgenePDLIM7chr5:176919406chr10:81072399ENST00000355841-413399_45793458.0DomainLIM zinc-binding 3
HgenePDLIM7chr5:176919406chr10:81072399ENST00000356618-412280_33893418.3333333333333DomainLIM zinc-binding 1
HgenePDLIM7chr5:176919406chr10:81072399ENST00000356618-412339_39893418.3333333333333DomainLIM zinc-binding 2
HgenePDLIM7chr5:176919406chr10:81072399ENST00000356618-412399_45793418.3333333333333DomainLIM zinc-binding 3
HgenePDLIM7chr5:176919406chr10:81072399ENST00000359895-413280_33893424.0DomainLIM zinc-binding 1
HgenePDLIM7chr5:176919406chr10:81072399ENST00000359895-413339_39893424.0DomainLIM zinc-binding 2
HgenePDLIM7chr5:176919406chr10:81072399ENST00000359895-413399_45793424.0DomainLIM zinc-binding 3
HgenePDLIM7chr5:176919406chr10:81072399ENST00000393551-49280_33893288.0DomainLIM zinc-binding 1
HgenePDLIM7chr5:176919406chr10:81072399ENST00000393551-49339_39893288.0DomainLIM zinc-binding 2
HgenePDLIM7chr5:176919406chr10:81072399ENST00000393551-49399_45793288.0DomainLIM zinc-binding 3
TgeneZMIZ1chr5:176919406chr10:81072399ENST000003345122325280_30510321068.0Compositional biasNote=Ala-rich
TgeneZMIZ1chr5:176919406chr10:81072399ENST000003345122325334_55510321068.0Compositional biasNote=Pro-rich
TgeneZMIZ1chr5:176919406chr10:81072399ENST000003345122325867_100210321068.0Compositional biasNote=Pro-rich
TgeneZMIZ1chr5:176919406chr10:81072399ENST000003345122325837_106710321068.0RegionTransactivation domain
TgeneZMIZ1chr5:176919406chr10:81072399ENST000003345122325727_80410321068.0Zinc fingerSP-RING-type


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Fusion Gene Sequence for PDLIM7-ZMIZ1


check button For in-frame fusion transcripts, we provide the fusion transcript sequences and fusion amino acid sequences. To have fusion amino acid sequence, we ran ORFfinder and chose the longest ORF among the all predicted ones.
>64017_64017_1_PDLIM7-ZMIZ1_PDLIM7_chr5_176919406_ENST00000355572_ZMIZ1_chr10_81072399_ENST00000334512_length(transcript)=4214nt_BP=336nt
CTCCCTGGAGCCCGACGCAGAGCAGCGCCCTGGCCGGGCCAAGCAGGAGCCGGCATCATGGATTCCTTCAAAGTAGTGCTGGAGGGGCCA
GCACCTTGGGGCTTCCGGCTGCAAGGGGGCAAGGACTTCAATGTGCCCCTCTCCATTTCCCGGCTCACTCCTGGGGGCAAAGCGGCGCAG
GCCGGAGTGGCCGTGGGTGACTGGGTGCTGAGCATCGATGGCGAGAATGCGGGTAGCCTCACACACATCGAAGCTCAGAACAAGATCCGG
GCCTGCGGGGAGCGCCTCAGCCTGGGCCTCAGCAGGGCCCAGCCGGTTCAGAGCAAACCGCAGAAGCTCCTTCCCGAACTCACAAATCCT
GACGAGCTCCTGTCTTATCTGGACCCCCCCGACCTGCCGAGCAATAGTAACGATGACCTCCTGTCTCTATTTGAGAACAACTGAGGGCCA
CCCGGTCGGGGCCATCCCTCCACACTCTGCATCCTACCCCACCTACCCAACACACTTTTCCACCTGGGAGCCTGTGCCCTCAGACCGCCC
CGCACCAGAGCCACGGGCTGTGGGGCGGGGAGCCCTCCCCCGCTGCAGCCCTCTCAGAACAGAGGGGTAGGGAGGGTGCACCAGTGCACC
AGGAAGGCTGTGTGGGTCTGGAGCCCACGTCCCACCTCCACACCCTTGGCTTGGGCCCATGCCCAGCGCAGGCCTGAAGACCACCCTCCC
GAGAGGAACCAGCCCGGTAAGAGGGCACACGCTGATGCGGCTTCCCGGTCCCTCCGCGTGTGCCGATTCCAGATGACCTTCCAGTGTCCC
CAAGGTTCTTCCATCTTCTAGACTGTAACCCTGCCTCCCTGCTTCCTGGTCCAGAGCCTCCCTCCAGTGACTGTGGAGCCTGAGAAGGCC
CCCGGGCCCCAGCATGGGCCCCGAGCCTTGGAGGAGCACTGGCAGTTGGTGGCAGTGAGACCAGCCCACCCACCACCACCCACCACAGAA
AAGCACAAACCTCTGGGAAAGACAACGTCTCTCGGGGGCCAGGGGTCATCGGTTTGACCCCTGACCTATAAGCCAAGATACCCCATAAAC
ACACTCAGAAAGCAGAGAAAAAGGACAAGAGTCTGTGTTTGAGAGGGGGTCTGCCATTCCTGCTTGGGGACTGGTGGGGAAGAGGGCCAG
GACATCTTCTGAGCCAGGACGTCCCTGAGGCTCCACCTCCAAGCTCAGACAGGGCCCAGGCTTGGGGAACAGAGAGAGCAGGTGTACACC
CAACCAAAGTGATTGTGCCCTTGGTTGGGGGGCGCGGGCATATAACCTGTCAGAAGCAAACAGGAGCGGCAACTTCTAACTTTGCTCCAA
GCCACTCTCTTTTTAAACAGCAACAATTTAAAGCTATGAAGTCACCTGGAGAAAAGGAACGTTGCTCTTGGACAGCAAGCAAACCATTTC
TCTCCGTCTGTTCTGTTTTTCTCCTAGTCCCTCTCCTGCCACCTCTCCAAGACTTCCGTGGGACACCCACTTCCCTCTGTCCTAGTTCTC
TTTGTCCAATCAGATGGCAAGGGCAGTGCGTGGAAAGGCCGGGGAGGTGCAGAAACCAGAGCCCAGGGCAATGGTGTCTGTCCAGCCCCT
CCCTCTGTCCCTGTGCTCCAAGCTGCCCCCGGCTGCAGCCCAGGCCATGGACATGTGCACCAGTATGTACCTGCAGGCATGGGGGGGAGG
GGGGCGTGTTTCTGGGCCTGCCCCAGACACTGCCCTTGGCTGCCAGCCTACCCTGCCTGCACTCCTCCACCATCACAATCTCACCCAAAC
TCCTGCTCACTCAAGCAAAAGCAGCCTCTGGCCTTCCCTCCACCGCTTTGCTCCATCTGGCTTACCACTCTCCAGGGCCTCCTGGGGAGC
CTGTCCTGTGTTCACTTTGTTTCAGGCTGGTCTGTGCCCCGTGAGCCACATGGCCTAGGGTGATGCCAGGTTGTCCCGTCACTGGGGTCC
CATCTGTAAATTCTTTGCGCCCTTCCCGGCTGCTGCCTGGGGCCCTTTCCTGCTCTCCCGTCCGCTGTGGGTGGTCCCCAGCTCTCCTCT
GTGGGTTTTACCGGAAAGGTGGCCCCAGCTGTTGACTTCCAGTCACTGTCCCAGACGGCACAAGGTTTTCTGTAGGAAAGCTGCCATTGC
CCCGGCCCCTTTTCTTCCTTTGTCCCGTTGTCGAGGTTTTTTCAAATAGCGTGTTGTTCAGTATGCAAATCAATTATTTTAAGAATCGCT
TTTGTAAATATCTTTGTGAATATTTTAGTATCGTCTTTGATAATATTCAACATTTTCATGACCTGGTTATAGCCTTTGCTGGTGTTTTTA
AAATACCTGGACTCAATGACAAAGACCGAGTCTTCTTTTTTTTTAAACAAAAACAAAAAAAGCAACCAGGGCTATTTGTACAGTTGAAGG
GGTGAACAGAATGGGCGGCTGTGCTGGGAGTTGGAAGACCGGGCAGCCCGCTATTTAGAGCCATCCCTCAGTCAGCTGGCAGGGACAAGC
CAACGCCAGGTAGCATGTGGCCACCCTTGCCCAGTGTCTGTGGCCTGGCAAGTGGCCACGCCCTGTGTCAGACCATCTGGGAATTAAGCT
CCAGACAGACTTACAGATGCCTTCCTTAGGAGTTCTTGCTTCTTGCGTTGATACTTTGCCCCAGAAAGGCCTGGGATTCATTCTGGTTCT
TATCAGGGTGTGTCCACACTCTGCTCACAGGTGGATCCACGGCTTTCCAGTGCGGAGAGTCGAGATGCTCCCTGCAGCCCAGGCCCCGGG
CACCTCCTGCAACCATCTCTGGGCTCAGCACCTGAGGCGGGTTTCCTGGGTCCCCTCTCCAGCAAGCCTCCACCAGCAAGCTCGGCCCAG
AGCTTCCCTTCCGGCTGGCTCTGAACCGTGCGTGGTGCCTACAGCCTGCAGTCTGGAGACAAGCTCTTCCGGAGTGCTCTGGGAGCCAGG
CCAGGGTGTGAGGGAGGTGCAGAGGCATCCGGGGCGGGAGCAAGCCCCAGGTTGTGACAGGTGCAGGTAGACAACGCCCATAAACAGAGA
TGGTCCTGAACTCTGGAGAGATCCTTCCCTGATCCTTTCGGACGACTACTTGGAGCCATAAGTAACCTCAGCAAAAACGAGGCCTCTGCA
AGCCACTTTTCCATGCCAAGCATCCACCCGGCCCACAGGCATGTTTCTGCCGCCACTCCGCAAGATGGACAGGGAGCCAGCAGGCAGGCG
GGAAGGGCCAAGTACAGGCAATCACCCCCATCTTCTTGGTTTGAAGCTTTATCCATGTATCATGTTCCGTGTAGCCATTTTATTTTTTAA
GAAACTGCTAATACTTTCTCCCTAATGGAAGCCCTGATCCCCCAGAGAGCTACAGGTCTGCTCCCGACGGGCCTCGGGCCTGACCCGTCC
ACACAGGGCCGTGTCAACAGCAGCGACTCAAGGGACGTGTGTACATATGTAAATGAGAAATAGAGACGTGTCAACAGATGCATTCATTTC
TCTTGGAATGTGTATTGTTTTTATTTTGCGAAACAAAACAAAACAAAAAAAAAAGCTTGGAACTCCATCACGTGGAAAAACTAGATCCTG
TTGGTTATAGCATTTGTGAGTTCTCCACGTCTGTCTCTCTCGCTCATGTAATATACTCTGACCCTGAGTGGAAAGGGGTTTTTGTTCTGT
TTTTATTTTACCTACATGTACTATTTAGCTTCAGTGTACTAGTCCTGCCACCTGTGTATTTTTAGGGTGCTATGGAAATAATGAAAAGAA
ACGGGGATTTCAGAAGAAAATTGTAACCAAATTCATACTTTGTATAATTTTTGATATCATGATCACAGGTGATTCACACGTACACACATA
AACACACCCACCAGTGCAGCCTGAAGTAACTCCCACAGAAACCATCATCGTCTTTGTACATCGTATGTACAATGCAATCATTTCATACTT
TAAACTGGTCAAAAAACTAATTGTGATTTCTAGTCTTGCAAAGCTGTATGTAGTTAGATGATGTGACAACCTCTAATATTTATCTAATAA
ATATGTATTCAGATGAAACCTGTATATTAGGTGTTCATGTGGTTATTTTGTATTTAAAGATCAAATTATTTGACTATTGCTAGACATTTC

>64017_64017_1_PDLIM7-ZMIZ1_PDLIM7_chr5_176919406_ENST00000355572_ZMIZ1_chr10_81072399_ENST00000334512_length(amino acids)=273AA_BP=
MCLRGGLPFLLGDWWGRGPGHLLSQDVPEAPPPSSDRAQAWGTERAGVHPTKVIVPLVGGRGHITCQKQTGAATSNFAPSHSLFKQQQFK
AMKSPGEKERCSWTASKPFLSVCSVFLLVPLLPPLQDFRGTPTSLCPSSLCPIRWQGQCVERPGRCRNQSPGQWCLSSPSLCPCAPSCPR
LQPRPWTCAPVCTCRHGGEGGVFLGLPQTLPLAASLPCLHSSTITISPKLLLTQAKAASGLPSTALLHLAYHSPGPPGEPVLCSLCFRLV

--------------------------------------------------------------
>64017_64017_2_PDLIM7-ZMIZ1_PDLIM7_chr5_176919406_ENST00000355841_ZMIZ1_chr10_81072399_ENST00000334512_length(transcript)=4224nt_BP=346nt
CCCAACGAGGCTCCCTGGAGCCCGACGCAGAGCAGCGCCCTGGCCGGGCCAAGCAGGAGCCGGCATCATGGATTCCTTCAAAGTAGTGCT
GGAGGGGCCAGCACCTTGGGGCTTCCGGCTGCAAGGGGGCAAGGACTTCAATGTGCCCCTCTCCATTTCCCGGCTCACTCCTGGGGGCAA
AGCGGCGCAGGCCGGAGTGGCCGTGGGTGACTGGGTGCTGAGCATCGATGGCGAGAATGCGGGTAGCCTCACACACATCGAAGCTCAGAA
CAAGATCCGGGCCTGCGGGGAGCGCCTCAGCCTGGGCCTCAGCAGGGCCCAGCCGGTTCAGAGCAAACCGCAGAAGCTCCTTCCCGAACT
CACAAATCCTGACGAGCTCCTGTCTTATCTGGACCCCCCCGACCTGCCGAGCAATAGTAACGATGACCTCCTGTCTCTATTTGAGAACAA
CTGAGGGCCACCCGGTCGGGGCCATCCCTCCACACTCTGCATCCTACCCCACCTACCCAACACACTTTTCCACCTGGGAGCCTGTGCCCT
CAGACCGCCCCGCACCAGAGCCACGGGCTGTGGGGCGGGGAGCCCTCCCCCGCTGCAGCCCTCTCAGAACAGAGGGGTAGGGAGGGTGCA
CCAGTGCACCAGGAAGGCTGTGTGGGTCTGGAGCCCACGTCCCACCTCCACACCCTTGGCTTGGGCCCATGCCCAGCGCAGGCCTGAAGA
CCACCCTCCCGAGAGGAACCAGCCCGGTAAGAGGGCACACGCTGATGCGGCTTCCCGGTCCCTCCGCGTGTGCCGATTCCAGATGACCTT
CCAGTGTCCCCAAGGTTCTTCCATCTTCTAGACTGTAACCCTGCCTCCCTGCTTCCTGGTCCAGAGCCTCCCTCCAGTGACTGTGGAGCC
TGAGAAGGCCCCCGGGCCCCAGCATGGGCCCCGAGCCTTGGAGGAGCACTGGCAGTTGGTGGCAGTGAGACCAGCCCACCCACCACCACC
CACCACAGAAAAGCACAAACCTCTGGGAAAGACAACGTCTCTCGGGGGCCAGGGGTCATCGGTTTGACCCCTGACCTATAAGCCAAGATA
CCCCATAAACACACTCAGAAAGCAGAGAAAAAGGACAAGAGTCTGTGTTTGAGAGGGGGTCTGCCATTCCTGCTTGGGGACTGGTGGGGA
AGAGGGCCAGGACATCTTCTGAGCCAGGACGTCCCTGAGGCTCCACCTCCAAGCTCAGACAGGGCCCAGGCTTGGGGAACAGAGAGAGCA
GGTGTACACCCAACCAAAGTGATTGTGCCCTTGGTTGGGGGGCGCGGGCATATAACCTGTCAGAAGCAAACAGGAGCGGCAACTTCTAAC
TTTGCTCCAAGCCACTCTCTTTTTAAACAGCAACAATTTAAAGCTATGAAGTCACCTGGAGAAAAGGAACGTTGCTCTTGGACAGCAAGC
AAACCATTTCTCTCCGTCTGTTCTGTTTTTCTCCTAGTCCCTCTCCTGCCACCTCTCCAAGACTTCCGTGGGACACCCACTTCCCTCTGT
CCTAGTTCTCTTTGTCCAATCAGATGGCAAGGGCAGTGCGTGGAAAGGCCGGGGAGGTGCAGAAACCAGAGCCCAGGGCAATGGTGTCTG
TCCAGCCCCTCCCTCTGTCCCTGTGCTCCAAGCTGCCCCCGGCTGCAGCCCAGGCCATGGACATGTGCACCAGTATGTACCTGCAGGCAT
GGGGGGGAGGGGGGCGTGTTTCTGGGCCTGCCCCAGACACTGCCCTTGGCTGCCAGCCTACCCTGCCTGCACTCCTCCACCATCACAATC
TCACCCAAACTCCTGCTCACTCAAGCAAAAGCAGCCTCTGGCCTTCCCTCCACCGCTTTGCTCCATCTGGCTTACCACTCTCCAGGGCCT
CCTGGGGAGCCTGTCCTGTGTTCACTTTGTTTCAGGCTGGTCTGTGCCCCGTGAGCCACATGGCCTAGGGTGATGCCAGGTTGTCCCGTC
ACTGGGGTCCCATCTGTAAATTCTTTGCGCCCTTCCCGGCTGCTGCCTGGGGCCCTTTCCTGCTCTCCCGTCCGCTGTGGGTGGTCCCCA
GCTCTCCTCTGTGGGTTTTACCGGAAAGGTGGCCCCAGCTGTTGACTTCCAGTCACTGTCCCAGACGGCACAAGGTTTTCTGTAGGAAAG
CTGCCATTGCCCCGGCCCCTTTTCTTCCTTTGTCCCGTTGTCGAGGTTTTTTCAAATAGCGTGTTGTTCAGTATGCAAATCAATTATTTT
AAGAATCGCTTTTGTAAATATCTTTGTGAATATTTTAGTATCGTCTTTGATAATATTCAACATTTTCATGACCTGGTTATAGCCTTTGCT
GGTGTTTTTAAAATACCTGGACTCAATGACAAAGACCGAGTCTTCTTTTTTTTTAAACAAAAACAAAAAAAGCAACCAGGGCTATTTGTA
CAGTTGAAGGGGTGAACAGAATGGGCGGCTGTGCTGGGAGTTGGAAGACCGGGCAGCCCGCTATTTAGAGCCATCCCTCAGTCAGCTGGC
AGGGACAAGCCAACGCCAGGTAGCATGTGGCCACCCTTGCCCAGTGTCTGTGGCCTGGCAAGTGGCCACGCCCTGTGTCAGACCATCTGG
GAATTAAGCTCCAGACAGACTTACAGATGCCTTCCTTAGGAGTTCTTGCTTCTTGCGTTGATACTTTGCCCCAGAAAGGCCTGGGATTCA
TTCTGGTTCTTATCAGGGTGTGTCCACACTCTGCTCACAGGTGGATCCACGGCTTTCCAGTGCGGAGAGTCGAGATGCTCCCTGCAGCCC
AGGCCCCGGGCACCTCCTGCAACCATCTCTGGGCTCAGCACCTGAGGCGGGTTTCCTGGGTCCCCTCTCCAGCAAGCCTCCACCAGCAAG
CTCGGCCCAGAGCTTCCCTTCCGGCTGGCTCTGAACCGTGCGTGGTGCCTACAGCCTGCAGTCTGGAGACAAGCTCTTCCGGAGTGCTCT
GGGAGCCAGGCCAGGGTGTGAGGGAGGTGCAGAGGCATCCGGGGCGGGAGCAAGCCCCAGGTTGTGACAGGTGCAGGTAGACAACGCCCA
TAAACAGAGATGGTCCTGAACTCTGGAGAGATCCTTCCCTGATCCTTTCGGACGACTACTTGGAGCCATAAGTAACCTCAGCAAAAACGA
GGCCTCTGCAAGCCACTTTTCCATGCCAAGCATCCACCCGGCCCACAGGCATGTTTCTGCCGCCACTCCGCAAGATGGACAGGGAGCCAG
CAGGCAGGCGGGAAGGGCCAAGTACAGGCAATCACCCCCATCTTCTTGGTTTGAAGCTTTATCCATGTATCATGTTCCGTGTAGCCATTT
TATTTTTTAAGAAACTGCTAATACTTTCTCCCTAATGGAAGCCCTGATCCCCCAGAGAGCTACAGGTCTGCTCCCGACGGGCCTCGGGCC
TGACCCGTCCACACAGGGCCGTGTCAACAGCAGCGACTCAAGGGACGTGTGTACATATGTAAATGAGAAATAGAGACGTGTCAACAGATG
CATTCATTTCTCTTGGAATGTGTATTGTTTTTATTTTGCGAAACAAAACAAAACAAAAAAAAAAGCTTGGAACTCCATCACGTGGAAAAA
CTAGATCCTGTTGGTTATAGCATTTGTGAGTTCTCCACGTCTGTCTCTCTCGCTCATGTAATATACTCTGACCCTGAGTGGAAAGGGGTT
TTTGTTCTGTTTTTATTTTACCTACATGTACTATTTAGCTTCAGTGTACTAGTCCTGCCACCTGTGTATTTTTAGGGTGCTATGGAAATA
ATGAAAAGAAACGGGGATTTCAGAAGAAAATTGTAACCAAATTCATACTTTGTATAATTTTTGATATCATGATCACAGGTGATTCACACG
TACACACATAAACACACCCACCAGTGCAGCCTGAAGTAACTCCCACAGAAACCATCATCGTCTTTGTACATCGTATGTACAATGCAATCA
TTTCATACTTTAAACTGGTCAAAAAACTAATTGTGATTTCTAGTCTTGCAAAGCTGTATGTAGTTAGATGATGTGACAACCTCTAATATT
TATCTAATAAATATGTATTCAGATGAAACCTGTATATTAGGTGTTCATGTGGTTATTTTGTATTTAAAGATCAAATTATTTGACTATTGC

>64017_64017_2_PDLIM7-ZMIZ1_PDLIM7_chr5_176919406_ENST00000355841_ZMIZ1_chr10_81072399_ENST00000334512_length(amino acids)=273AA_BP=
MCLRGGLPFLLGDWWGRGPGHLLSQDVPEAPPPSSDRAQAWGTERAGVHPTKVIVPLVGGRGHITCQKQTGAATSNFAPSHSLFKQQQFK
AMKSPGEKERCSWTASKPFLSVCSVFLLVPLLPPLQDFRGTPTSLCPSSLCPIRWQGQCVERPGRCRNQSPGQWCLSSPSLCPCAPSCPR
LQPRPWTCAPVCTCRHGGEGGVFLGLPQTLPLAASLPCLHSSTITISPKLLLTQAKAASGLPSTALLHLAYHSPGPPGEPVLCSLCFRLV

--------------------------------------------------------------
>64017_64017_3_PDLIM7-ZMIZ1_PDLIM7_chr5_176919406_ENST00000359895_ZMIZ1_chr10_81072399_ENST00000334512_length(transcript)=4202nt_BP=324nt
CGACGCAGAGCAGCGCCCTGGCCGGGCCAAGCAGGAGCCGGCATCATGGATTCCTTCAAAGTAGTGCTGGAGGGGCCAGCACCTTGGGGC
TTCCGGCTGCAAGGGGGCAAGGACTTCAATGTGCCCCTCTCCATTTCCCGGCTCACTCCTGGGGGCAAAGCGGCGCAGGCCGGAGTGGCC
GTGGGTGACTGGGTGCTGAGCATCGATGGCGAGAATGCGGGTAGCCTCACACACATCGAAGCTCAGAACAAGATCCGGGCCTGCGGGGAG
CGCCTCAGCCTGGGCCTCAGCAGGGCCCAGCCGGTTCAGAGCAAACCGCAGAAGCTCCTTCCCGAACTCACAAATCCTGACGAGCTCCTG
TCTTATCTGGACCCCCCCGACCTGCCGAGCAATAGTAACGATGACCTCCTGTCTCTATTTGAGAACAACTGAGGGCCACCCGGTCGGGGC
CATCCCTCCACACTCTGCATCCTACCCCACCTACCCAACACACTTTTCCACCTGGGAGCCTGTGCCCTCAGACCGCCCCGCACCAGAGCC
ACGGGCTGTGGGGCGGGGAGCCCTCCCCCGCTGCAGCCCTCTCAGAACAGAGGGGTAGGGAGGGTGCACCAGTGCACCAGGAAGGCTGTG
TGGGTCTGGAGCCCACGTCCCACCTCCACACCCTTGGCTTGGGCCCATGCCCAGCGCAGGCCTGAAGACCACCCTCCCGAGAGGAACCAG
CCCGGTAAGAGGGCACACGCTGATGCGGCTTCCCGGTCCCTCCGCGTGTGCCGATTCCAGATGACCTTCCAGTGTCCCCAAGGTTCTTCC
ATCTTCTAGACTGTAACCCTGCCTCCCTGCTTCCTGGTCCAGAGCCTCCCTCCAGTGACTGTGGAGCCTGAGAAGGCCCCCGGGCCCCAG
CATGGGCCCCGAGCCTTGGAGGAGCACTGGCAGTTGGTGGCAGTGAGACCAGCCCACCCACCACCACCCACCACAGAAAAGCACAAACCT
CTGGGAAAGACAACGTCTCTCGGGGGCCAGGGGTCATCGGTTTGACCCCTGACCTATAAGCCAAGATACCCCATAAACACACTCAGAAAG
CAGAGAAAAAGGACAAGAGTCTGTGTTTGAGAGGGGGTCTGCCATTCCTGCTTGGGGACTGGTGGGGAAGAGGGCCAGGACATCTTCTGA
GCCAGGACGTCCCTGAGGCTCCACCTCCAAGCTCAGACAGGGCCCAGGCTTGGGGAACAGAGAGAGCAGGTGTACACCCAACCAAAGTGA
TTGTGCCCTTGGTTGGGGGGCGCGGGCATATAACCTGTCAGAAGCAAACAGGAGCGGCAACTTCTAACTTTGCTCCAAGCCACTCTCTTT
TTAAACAGCAACAATTTAAAGCTATGAAGTCACCTGGAGAAAAGGAACGTTGCTCTTGGACAGCAAGCAAACCATTTCTCTCCGTCTGTT
CTGTTTTTCTCCTAGTCCCTCTCCTGCCACCTCTCCAAGACTTCCGTGGGACACCCACTTCCCTCTGTCCTAGTTCTCTTTGTCCAATCA
GATGGCAAGGGCAGTGCGTGGAAAGGCCGGGGAGGTGCAGAAACCAGAGCCCAGGGCAATGGTGTCTGTCCAGCCCCTCCCTCTGTCCCT
GTGCTCCAAGCTGCCCCCGGCTGCAGCCCAGGCCATGGACATGTGCACCAGTATGTACCTGCAGGCATGGGGGGGAGGGGGGCGTGTTTC
TGGGCCTGCCCCAGACACTGCCCTTGGCTGCCAGCCTACCCTGCCTGCACTCCTCCACCATCACAATCTCACCCAAACTCCTGCTCACTC
AAGCAAAAGCAGCCTCTGGCCTTCCCTCCACCGCTTTGCTCCATCTGGCTTACCACTCTCCAGGGCCTCCTGGGGAGCCTGTCCTGTGTT
CACTTTGTTTCAGGCTGGTCTGTGCCCCGTGAGCCACATGGCCTAGGGTGATGCCAGGTTGTCCCGTCACTGGGGTCCCATCTGTAAATT
CTTTGCGCCCTTCCCGGCTGCTGCCTGGGGCCCTTTCCTGCTCTCCCGTCCGCTGTGGGTGGTCCCCAGCTCTCCTCTGTGGGTTTTACC
GGAAAGGTGGCCCCAGCTGTTGACTTCCAGTCACTGTCCCAGACGGCACAAGGTTTTCTGTAGGAAAGCTGCCATTGCCCCGGCCCCTTT
TCTTCCTTTGTCCCGTTGTCGAGGTTTTTTCAAATAGCGTGTTGTTCAGTATGCAAATCAATTATTTTAAGAATCGCTTTTGTAAATATC
TTTGTGAATATTTTAGTATCGTCTTTGATAATATTCAACATTTTCATGACCTGGTTATAGCCTTTGCTGGTGTTTTTAAAATACCTGGAC
TCAATGACAAAGACCGAGTCTTCTTTTTTTTTAAACAAAAACAAAAAAAGCAACCAGGGCTATTTGTACAGTTGAAGGGGTGAACAGAAT
GGGCGGCTGTGCTGGGAGTTGGAAGACCGGGCAGCCCGCTATTTAGAGCCATCCCTCAGTCAGCTGGCAGGGACAAGCCAACGCCAGGTA
GCATGTGGCCACCCTTGCCCAGTGTCTGTGGCCTGGCAAGTGGCCACGCCCTGTGTCAGACCATCTGGGAATTAAGCTCCAGACAGACTT
ACAGATGCCTTCCTTAGGAGTTCTTGCTTCTTGCGTTGATACTTTGCCCCAGAAAGGCCTGGGATTCATTCTGGTTCTTATCAGGGTGTG
TCCACACTCTGCTCACAGGTGGATCCACGGCTTTCCAGTGCGGAGAGTCGAGATGCTCCCTGCAGCCCAGGCCCCGGGCACCTCCTGCAA
CCATCTCTGGGCTCAGCACCTGAGGCGGGTTTCCTGGGTCCCCTCTCCAGCAAGCCTCCACCAGCAAGCTCGGCCCAGAGCTTCCCTTCC
GGCTGGCTCTGAACCGTGCGTGGTGCCTACAGCCTGCAGTCTGGAGACAAGCTCTTCCGGAGTGCTCTGGGAGCCAGGCCAGGGTGTGAG
GGAGGTGCAGAGGCATCCGGGGCGGGAGCAAGCCCCAGGTTGTGACAGGTGCAGGTAGACAACGCCCATAAACAGAGATGGTCCTGAACT
CTGGAGAGATCCTTCCCTGATCCTTTCGGACGACTACTTGGAGCCATAAGTAACCTCAGCAAAAACGAGGCCTCTGCAAGCCACTTTTCC
ATGCCAAGCATCCACCCGGCCCACAGGCATGTTTCTGCCGCCACTCCGCAAGATGGACAGGGAGCCAGCAGGCAGGCGGGAAGGGCCAAG
TACAGGCAATCACCCCCATCTTCTTGGTTTGAAGCTTTATCCATGTATCATGTTCCGTGTAGCCATTTTATTTTTTAAGAAACTGCTAAT
ACTTTCTCCCTAATGGAAGCCCTGATCCCCCAGAGAGCTACAGGTCTGCTCCCGACGGGCCTCGGGCCTGACCCGTCCACACAGGGCCGT
GTCAACAGCAGCGACTCAAGGGACGTGTGTACATATGTAAATGAGAAATAGAGACGTGTCAACAGATGCATTCATTTCTCTTGGAATGTG
TATTGTTTTTATTTTGCGAAACAAAACAAAACAAAAAAAAAAGCTTGGAACTCCATCACGTGGAAAAACTAGATCCTGTTGGTTATAGCA
TTTGTGAGTTCTCCACGTCTGTCTCTCTCGCTCATGTAATATACTCTGACCCTGAGTGGAAAGGGGTTTTTGTTCTGTTTTTATTTTACC
TACATGTACTATTTAGCTTCAGTGTACTAGTCCTGCCACCTGTGTATTTTTAGGGTGCTATGGAAATAATGAAAAGAAACGGGGATTTCA
GAAGAAAATTGTAACCAAATTCATACTTTGTATAATTTTTGATATCATGATCACAGGTGATTCACACGTACACACATAAACACACCCACC
AGTGCAGCCTGAAGTAACTCCCACAGAAACCATCATCGTCTTTGTACATCGTATGTACAATGCAATCATTTCATACTTTAAACTGGTCAA
AAAACTAATTGTGATTTCTAGTCTTGCAAAGCTGTATGTAGTTAGATGATGTGACAACCTCTAATATTTATCTAATAAATATGTATTCAG
ATGAAACCTGTATATTAGGTGTTCATGTGGTTATTTTGTATTTAAAGATCAAATTATTTGACTATTGCTAGACATTTCTATACTCTGTTG

>64017_64017_3_PDLIM7-ZMIZ1_PDLIM7_chr5_176919406_ENST00000359895_ZMIZ1_chr10_81072399_ENST00000334512_length(amino acids)=273AA_BP=
MCLRGGLPFLLGDWWGRGPGHLLSQDVPEAPPPSSDRAQAWGTERAGVHPTKVIVPLVGGRGHITCQKQTGAATSNFAPSHSLFKQQQFK
AMKSPGEKERCSWTASKPFLSVCSVFLLVPLLPPLQDFRGTPTSLCPSSLCPIRWQGQCVERPGRCRNQSPGQWCLSSPSLCPCAPSCPR
LQPRPWTCAPVCTCRHGGEGGVFLGLPQTLPLAASLPCLHSSTITISPKLLLTQAKAASGLPSTALLHLAYHSPGPPGEPVLCSLCFRLV

--------------------------------------------------------------
>64017_64017_4_PDLIM7-ZMIZ1_PDLIM7_chr5_176919406_ENST00000393551_ZMIZ1_chr10_81072399_ENST00000334512_length(transcript)=4224nt_BP=346nt
CCCAACGAGGCTCCCTGGAGCCCGACGCAGAGCAGCGCCCTGGCCGGGCCAAGCAGGAGCCGGCATCATGGATTCCTTCAAAGTAGTGCT
GGAGGGGCCAGCACCTTGGGGCTTCCGGCTGCAAGGGGGCAAGGACTTCAATGTGCCCCTCTCCATTTCCCGGCTCACTCCTGGGGGCAA
AGCGGCGCAGGCCGGAGTGGCCGTGGGTGACTGGGTGCTGAGCATCGATGGCGAGAATGCGGGTAGCCTCACACACATCGAAGCTCAGAA
CAAGATCCGGGCCTGCGGGGAGCGCCTCAGCCTGGGCCTCAGCAGGGCCCAGCCGGTTCAGAGCAAACCGCAGAAGCTCCTTCCCGAACT
CACAAATCCTGACGAGCTCCTGTCTTATCTGGACCCCCCCGACCTGCCGAGCAATAGTAACGATGACCTCCTGTCTCTATTTGAGAACAA
CTGAGGGCCACCCGGTCGGGGCCATCCCTCCACACTCTGCATCCTACCCCACCTACCCAACACACTTTTCCACCTGGGAGCCTGTGCCCT
CAGACCGCCCCGCACCAGAGCCACGGGCTGTGGGGCGGGGAGCCCTCCCCCGCTGCAGCCCTCTCAGAACAGAGGGGTAGGGAGGGTGCA
CCAGTGCACCAGGAAGGCTGTGTGGGTCTGGAGCCCACGTCCCACCTCCACACCCTTGGCTTGGGCCCATGCCCAGCGCAGGCCTGAAGA
CCACCCTCCCGAGAGGAACCAGCCCGGTAAGAGGGCACACGCTGATGCGGCTTCCCGGTCCCTCCGCGTGTGCCGATTCCAGATGACCTT
CCAGTGTCCCCAAGGTTCTTCCATCTTCTAGACTGTAACCCTGCCTCCCTGCTTCCTGGTCCAGAGCCTCCCTCCAGTGACTGTGGAGCC
TGAGAAGGCCCCCGGGCCCCAGCATGGGCCCCGAGCCTTGGAGGAGCACTGGCAGTTGGTGGCAGTGAGACCAGCCCACCCACCACCACC
CACCACAGAAAAGCACAAACCTCTGGGAAAGACAACGTCTCTCGGGGGCCAGGGGTCATCGGTTTGACCCCTGACCTATAAGCCAAGATA
CCCCATAAACACACTCAGAAAGCAGAGAAAAAGGACAAGAGTCTGTGTTTGAGAGGGGGTCTGCCATTCCTGCTTGGGGACTGGTGGGGA
AGAGGGCCAGGACATCTTCTGAGCCAGGACGTCCCTGAGGCTCCACCTCCAAGCTCAGACAGGGCCCAGGCTTGGGGAACAGAGAGAGCA
GGTGTACACCCAACCAAAGTGATTGTGCCCTTGGTTGGGGGGCGCGGGCATATAACCTGTCAGAAGCAAACAGGAGCGGCAACTTCTAAC
TTTGCTCCAAGCCACTCTCTTTTTAAACAGCAACAATTTAAAGCTATGAAGTCACCTGGAGAAAAGGAACGTTGCTCTTGGACAGCAAGC
AAACCATTTCTCTCCGTCTGTTCTGTTTTTCTCCTAGTCCCTCTCCTGCCACCTCTCCAAGACTTCCGTGGGACACCCACTTCCCTCTGT
CCTAGTTCTCTTTGTCCAATCAGATGGCAAGGGCAGTGCGTGGAAAGGCCGGGGAGGTGCAGAAACCAGAGCCCAGGGCAATGGTGTCTG
TCCAGCCCCTCCCTCTGTCCCTGTGCTCCAAGCTGCCCCCGGCTGCAGCCCAGGCCATGGACATGTGCACCAGTATGTACCTGCAGGCAT
GGGGGGGAGGGGGGCGTGTTTCTGGGCCTGCCCCAGACACTGCCCTTGGCTGCCAGCCTACCCTGCCTGCACTCCTCCACCATCACAATC
TCACCCAAACTCCTGCTCACTCAAGCAAAAGCAGCCTCTGGCCTTCCCTCCACCGCTTTGCTCCATCTGGCTTACCACTCTCCAGGGCCT
CCTGGGGAGCCTGTCCTGTGTTCACTTTGTTTCAGGCTGGTCTGTGCCCCGTGAGCCACATGGCCTAGGGTGATGCCAGGTTGTCCCGTC
ACTGGGGTCCCATCTGTAAATTCTTTGCGCCCTTCCCGGCTGCTGCCTGGGGCCCTTTCCTGCTCTCCCGTCCGCTGTGGGTGGTCCCCA
GCTCTCCTCTGTGGGTTTTACCGGAAAGGTGGCCCCAGCTGTTGACTTCCAGTCACTGTCCCAGACGGCACAAGGTTTTCTGTAGGAAAG
CTGCCATTGCCCCGGCCCCTTTTCTTCCTTTGTCCCGTTGTCGAGGTTTTTTCAAATAGCGTGTTGTTCAGTATGCAAATCAATTATTTT
AAGAATCGCTTTTGTAAATATCTTTGTGAATATTTTAGTATCGTCTTTGATAATATTCAACATTTTCATGACCTGGTTATAGCCTTTGCT
GGTGTTTTTAAAATACCTGGACTCAATGACAAAGACCGAGTCTTCTTTTTTTTTAAACAAAAACAAAAAAAGCAACCAGGGCTATTTGTA
CAGTTGAAGGGGTGAACAGAATGGGCGGCTGTGCTGGGAGTTGGAAGACCGGGCAGCCCGCTATTTAGAGCCATCCCTCAGTCAGCTGGC
AGGGACAAGCCAACGCCAGGTAGCATGTGGCCACCCTTGCCCAGTGTCTGTGGCCTGGCAAGTGGCCACGCCCTGTGTCAGACCATCTGG
GAATTAAGCTCCAGACAGACTTACAGATGCCTTCCTTAGGAGTTCTTGCTTCTTGCGTTGATACTTTGCCCCAGAAAGGCCTGGGATTCA
TTCTGGTTCTTATCAGGGTGTGTCCACACTCTGCTCACAGGTGGATCCACGGCTTTCCAGTGCGGAGAGTCGAGATGCTCCCTGCAGCCC
AGGCCCCGGGCACCTCCTGCAACCATCTCTGGGCTCAGCACCTGAGGCGGGTTTCCTGGGTCCCCTCTCCAGCAAGCCTCCACCAGCAAG
CTCGGCCCAGAGCTTCCCTTCCGGCTGGCTCTGAACCGTGCGTGGTGCCTACAGCCTGCAGTCTGGAGACAAGCTCTTCCGGAGTGCTCT
GGGAGCCAGGCCAGGGTGTGAGGGAGGTGCAGAGGCATCCGGGGCGGGAGCAAGCCCCAGGTTGTGACAGGTGCAGGTAGACAACGCCCA
TAAACAGAGATGGTCCTGAACTCTGGAGAGATCCTTCCCTGATCCTTTCGGACGACTACTTGGAGCCATAAGTAACCTCAGCAAAAACGA
GGCCTCTGCAAGCCACTTTTCCATGCCAAGCATCCACCCGGCCCACAGGCATGTTTCTGCCGCCACTCCGCAAGATGGACAGGGAGCCAG
CAGGCAGGCGGGAAGGGCCAAGTACAGGCAATCACCCCCATCTTCTTGGTTTGAAGCTTTATCCATGTATCATGTTCCGTGTAGCCATTT
TATTTTTTAAGAAACTGCTAATACTTTCTCCCTAATGGAAGCCCTGATCCCCCAGAGAGCTACAGGTCTGCTCCCGACGGGCCTCGGGCC
TGACCCGTCCACACAGGGCCGTGTCAACAGCAGCGACTCAAGGGACGTGTGTACATATGTAAATGAGAAATAGAGACGTGTCAACAGATG
CATTCATTTCTCTTGGAATGTGTATTGTTTTTATTTTGCGAAACAAAACAAAACAAAAAAAAAAGCTTGGAACTCCATCACGTGGAAAAA
CTAGATCCTGTTGGTTATAGCATTTGTGAGTTCTCCACGTCTGTCTCTCTCGCTCATGTAATATACTCTGACCCTGAGTGGAAAGGGGTT
TTTGTTCTGTTTTTATTTTACCTACATGTACTATTTAGCTTCAGTGTACTAGTCCTGCCACCTGTGTATTTTTAGGGTGCTATGGAAATA
ATGAAAAGAAACGGGGATTTCAGAAGAAAATTGTAACCAAATTCATACTTTGTATAATTTTTGATATCATGATCACAGGTGATTCACACG
TACACACATAAACACACCCACCAGTGCAGCCTGAAGTAACTCCCACAGAAACCATCATCGTCTTTGTACATCGTATGTACAATGCAATCA
TTTCATACTTTAAACTGGTCAAAAAACTAATTGTGATTTCTAGTCTTGCAAAGCTGTATGTAGTTAGATGATGTGACAACCTCTAATATT
TATCTAATAAATATGTATTCAGATGAAACCTGTATATTAGGTGTTCATGTGGTTATTTTGTATTTAAAGATCAAATTATTTGACTATTGC

>64017_64017_4_PDLIM7-ZMIZ1_PDLIM7_chr5_176919406_ENST00000393551_ZMIZ1_chr10_81072399_ENST00000334512_length(amino acids)=273AA_BP=
MCLRGGLPFLLGDWWGRGPGHLLSQDVPEAPPPSSDRAQAWGTERAGVHPTKVIVPLVGGRGHITCQKQTGAATSNFAPSHSLFKQQQFK
AMKSPGEKERCSWTASKPFLSVCSVFLLVPLLPPLQDFRGTPTSLCPSSLCPIRWQGQCVERPGRCRNQSPGQWCLSSPSLCPCAPSCPR
LQPRPWTCAPVCTCRHGGEGGVFLGLPQTLPLAASLPCLHSSTITISPKLLLTQAKAASGLPSTALLHLAYHSPGPPGEPVLCSLCFRLV

--------------------------------------------------------------

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Fusion Gene PPI Analysis for PDLIM7-ZMIZ1


check button Go to ChiPPI (Chimeric Protein-Protein interactions) to see the chimeric PPI interaction in

ChiPPI page.


check button Protein-protein interactors with each fusion partner protein in wild-type (BIOGRID-3.4.160)
HgeneHgene's interactorsTgeneTgene's interactors


check button - Retained PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenStill interaction with


check button - Lost PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


check button - Retained PPIs, but lost function due to frame-shift fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


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Related Drugs for PDLIM7-ZMIZ1


check button Drugs targeting genes involved in this fusion gene.
(DrugBank Version 5.1.8 2021-05-08)
PartnerGeneUniProtAccDrugBank IDDrug nameDrug activityDrug typeDrug status

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Related Diseases for PDLIM7-ZMIZ1


check button Diseases associated with fusion partners.
(DisGeNet 4.0)
PartnerGeneDisease IDDisease name# pubmedsSource