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Center for Computational Systems Medicine
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Fusion Gene Summary

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Fusion Gene ORF analysis

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Fusion Genomic Features

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Fusion Protein Features

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Fusion Gene Sequence

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Fusion Gene PPI analysis

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Related Drugs

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Related Diseases

Fusion gene:PDZD2-COL27A1 (FusionGDB2 ID:64139)

Fusion Gene Summary for PDZD2-COL27A1

check button Fusion gene summary
Fusion gene informationFusion gene name: PDZD2-COL27A1
Fusion gene ID: 64139
HgeneTgene
Gene symbol

PDZD2

COL27A1

Gene ID

23037

85301

Gene namePDZ domain containing 2collagen type XXVII alpha 1 chain
SynonymsAIPC|PAPIN|PDZK3|PIN1STLS
Cytomap

5p13.3

9q32

Type of geneprotein-codingprotein-coding
DescriptionPDZ domain-containing protein 2PDZ domain-containing protein 3activated in prostate cancer proteinplakophilin-related armadillo repeat protein-interactive PDZ proteincollagen alpha-1(XXVII) chaincollagen, type XXVII, alpha 1
Modification date2020031320200313
UniProtAcc.

Q8IZC6

Ensembl transtripts involved in fusion geneENST00000282493, ENST00000438447, 
ENST00000513490, 		ENST00000477421, 
ENST00000356083, 
Fusion gene scores* DoF score11 X 14 X 5=7707 X 8 X 5=280
# samples 148
** MAII scorelog2(14/770*10)=-2.4594316186373
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0		log2(8/280*10)=-1.8073549220576
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0
Context

PubMed: PDZD2 [Title/Abstract] AND COL27A1 [Title/Abstract] AND fusion [Title/Abstract]

Most frequent breakpointPDZD2(32093130)-COL27A1(117014873), # samples:2
Anticipated loss of major functional domain due to fusion event.
* DoF score (Degree of Frequency) = # partners X # break points X # cancer types
** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10)

check button Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez
PartnerGeneGO IDGO termPubMed ID

check buttonFusion gene breakpoints across PDZD2 (5'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.
all structure

check buttonFusion gene breakpoints across COL27A1 (3'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.
all structure

check button Fusion gene information from two resources (ChiTars 5.0 and ChimerDB 4.0)
* All genome coordinats were lifted-over on hg19.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
SourceDiseaseSampleHgeneHchrHbpHstrandTgeneTchrTbpTstrand
ChimerDB4LUADTCGA-97-A4M1-01APDZD2chr5

32093130

-COL27A1chr9

117014873

+
ChimerDB4LUADTCGA-97-A4M1-01APDZD2chr5

32093130

+COL27A1chr9

117014873

+


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Fusion Gene ORF analysis for PDZD2-COL27A1

check button Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
ORFHenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrand
5CDS-intronENST00000282493ENST00000477421PDZD2chr5

32093130

+COL27A1chr9

117014873

+
5CDS-intronENST00000438447ENST00000477421PDZD2chr5

32093130

+COL27A1chr9

117014873

+
In-frameENST00000282493ENST00000356083PDZD2chr5

32093130

+COL27A1chr9

117014873

+
In-frameENST00000438447ENST00000356083PDZD2chr5

32093130

+COL27A1chr9

117014873

+
intron-3CDSENST00000513490ENST00000356083PDZD2chr5

32093130

+COL27A1chr9

117014873

+
intron-intronENST00000513490ENST00000477421PDZD2chr5

32093130

+COL27A1chr9

117014873

+

check buttonORFfinder result based on the fusion transcript sequence of in-frame fusion genes.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandSeq length
(transcript)		BP loci
(transcript)		Predicted start
(transcript)		Predicted stop
(transcript)		Seq length
(amino acids)
ENST00000438447PDZD2chr532093130+ENST00000356083COL27A1chr9117014873+125998233373107823469
ENST00000282493PDZD2chr532093130+ENST00000356083COL27A1chr9117014873+125368170310107193469

check buttonDeepORF prediction of the coding potential based on the fusion transcript sequence of in-frame fusion genes. DeepORF is a coding potential classifier based on convolutional neural network by comparing the real Ribo-seq data. If the no-coding score < 0.5 and coding score > 0.5, then the in-frame fusion transcript is predicted as being likely translated.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandNo-coding scoreCoding score
ENST00000438447ENST00000356083PDZD2chr532093130+COL27A1chr9117014873+0.0033119540.99668807
ENST00000282493ENST00000356083PDZD2chr532093130+COL27A1chr9117014873+0.0030820640.99691796

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Fusion Genomic Features for PDZD2-COL27A1


check buttonFusionAI prediction of the potential fusion gene breakpoint based on the pre-mature RNA sequence context (+/- 5kb of individual partner genes, total 20kb length sequence). FusionAI is a fusion gene breakpoint classifier based on convolutional neural network by comparing the fusion positive and negative sequence context of ~ 20K fusion gene data. From here, we can have the relative potentency of the 20K genomic sequence how individual sequnce will be likely used as the gene fusion breakpoints.
HgeneHchrHbpHstrandTgeneTchrTbpTstrand1-pp (fusion gene breakpoint)
PDZD2chr532093130+COL27A1chr9117014872+0.303683370.6963166
PDZD2chr532093130+COL27A1chr9117014872+0.303683370.6963166

check buttonDistribution of 44 human genomic features loci across 20kb length fusion breakpoint regions. We integrated a total of 44 different types of human genomic feature loci information across five big categories including virus integration sites, repeats, structural variants, chromatin states, and gene expression regulation. More details are in help page.
genomic feature

check buttonDistribution of 44 human genomic features loci across 20kb length fusion breakpoint regions that are ovelapped with the top 1% feature importance score regions. More details are in help page.
genomic feature of top 1%

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Fusion Protein Features for PDZD2-COL27A1


check button Four levels of functional features of fusion genes
Go to FGviewer search page for the most frequent breakpoint (https://ccsmweb.uth.edu/FGviewer/chr5:32093130/chr9:117014873)
- FGviewer provides the online visualization of the retention search of the protein functional features across DNA, RNA, protein, and pathological levels.
- How to search
1. Put your fusion gene symbol.
2. Press the tab key until there will be shown the breakpoint information filled.
4. Go down and press 'Search' tab twice.
4. Go down to have the hyperlink of the search result.
5. Click the hyperlink.
6. See the FGviewer result for your fusion gene.
FGviewer

check buttonMain function of each fusion partner protein. (from UniProt)
HgeneTgene
.COL27A1

Q8IZC6

FUNCTION: Transcriptional activator which is required for calcium-dependent dendritic growth and branching in cortical neurons. Recruits CREB-binding protein (CREBBP) to nuclear bodies. Component of the CREST-BRG1 complex, a multiprotein complex that regulates promoter activation by orchestrating a calcium-dependent release of a repressor complex and a recruitment of an activator complex. In resting neurons, transcription of the c-FOS promoter is inhibited by BRG1-dependent recruitment of a phospho-RB1-HDAC1 repressor complex. Upon calcium influx, RB1 is dephosphorylated by calcineurin, which leads to release of the repressor complex. At the same time, there is increased recruitment of CREBBP to the promoter by a CREST-dependent mechanism, which leads to transcriptional activation. The CREST-BRG1 complex also binds to the NR2B promoter, and activity-dependent induction of NR2B expression involves a release of HDAC1 and recruitment of CREBBP (By similarity). {ECO:0000250}.FUNCTION: Plays a role during the calcification of cartilage and the transition of cartilage to bone. {ECO:0000269|PubMed:17693149}.

check buttonRetention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at

download page


* Minus value of BPloci means that the break pointn is located before the CDS.
- In-frame and retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
HgenePDZD2chr5:32093130chr9:117014873ENST00000282493+20242139_219426152840.0Compositional biasNote=Ser-rich
HgenePDZD2chr5:32093130chr9:117014873ENST00000438447+21252139_219426152840.0Compositional biasNote=Ser-rich
HgenePDZD2chr5:32093130chr9:117014873ENST00000282493+2024334_41926152840.0DomainPDZ 2
HgenePDZD2chr5:32093130chr9:117014873ENST00000282493+2024586_67226152840.0DomainPDZ 3
HgenePDZD2chr5:32093130chr9:117014873ENST00000282493+2024728_81326152840.0DomainPDZ 4
HgenePDZD2chr5:32093130chr9:117014873ENST00000282493+202485_18226152840.0DomainPDZ 1
HgenePDZD2chr5:32093130chr9:117014873ENST00000438447+2125334_41926152840.0DomainPDZ 2
HgenePDZD2chr5:32093130chr9:117014873ENST00000438447+2125586_67226152840.0DomainPDZ 3
HgenePDZD2chr5:32093130chr9:117014873ENST00000438447+2125728_81326152840.0DomainPDZ 4
HgenePDZD2chr5:32093130chr9:117014873ENST00000438447+212585_18226152840.0DomainPDZ 1
TgeneCOL27A1chr5:32093130chr9:117014873ENST0000035608324611066_112510111861.0DomainNote=Collagen-like 8
TgeneCOL27A1chr5:32093130chr9:117014873ENST0000035608324611126_118510111861.0DomainNote=Collagen-like 9
TgeneCOL27A1chr5:32093130chr9:117014873ENST0000035608324611192_125110111861.0DomainNote=Collagen-like 10
TgeneCOL27A1chr5:32093130chr9:117014873ENST0000035608324611258_131710111861.0DomainNote=Collagen-like 11
TgeneCOL27A1chr5:32093130chr9:117014873ENST0000035608324611318_137810111861.0DomainNote=Collagen-like 12
TgeneCOL27A1chr5:32093130chr9:117014873ENST0000035608324611382_144110111861.0DomainNote=Collagen-like 13
TgeneCOL27A1chr5:32093130chr9:117014873ENST0000035608324611442_150110111861.0DomainNote=Collagen-like 14
TgeneCOL27A1chr5:32093130chr9:117014873ENST0000035608324611502_156110111861.0DomainNote=Collagen-like 15
TgeneCOL27A1chr5:32093130chr9:117014873ENST0000035608324611562_162110111861.0DomainNote=Collagen-like 16
TgeneCOL27A1chr5:32093130chr9:117014873ENST0000035608324611660_186010111861.0DomainFibrillar collagen NC1

- In-frame and not-retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
HgenePDZD2chr5:32093130chr9:117014873ENST00000282493+20242622_270626152840.0DomainPDZ 5
HgenePDZD2chr5:32093130chr9:117014873ENST00000282493+20242750_283526152840.0DomainPDZ 6
HgenePDZD2chr5:32093130chr9:117014873ENST00000438447+21252622_270626152840.0DomainPDZ 5
HgenePDZD2chr5:32093130chr9:117014873ENST00000438447+21252750_283526152840.0DomainPDZ 6
TgeneCOL27A1chr5:32093130chr9:117014873ENST000003560832461283_162110111861.0Compositional biasNote=Pro-rich
TgeneCOL27A1chr5:32093130chr9:117014873ENST0000035608324611003_106210111861.0DomainNote=Collagen-like 7
TgeneCOL27A1chr5:32093130chr9:117014873ENST000003560832461625_67910111861.0DomainNote=Collagen-like 1
TgeneCOL27A1chr5:32093130chr9:117014873ENST000003560832461688_74710111861.0DomainNote=Collagen-like 2
TgeneCOL27A1chr5:32093130chr9:117014873ENST00000356083246171_23610111861.0DomainNote=Laminin G-like
TgeneCOL27A1chr5:32093130chr9:117014873ENST000003560832461748_80710111861.0DomainNote=Collagen-like 3
TgeneCOL27A1chr5:32093130chr9:117014873ENST000003560832461808_86710111861.0DomainNote=Collagen-like 4
TgeneCOL27A1chr5:32093130chr9:117014873ENST000003560832461871_93010111861.0DomainNote=Collagen-like 5
TgeneCOL27A1chr5:32093130chr9:117014873ENST000003560832461931_99010111861.0DomainNote=Collagen-like 6
TgeneCOL27A1chr5:32093130chr9:117014873ENST000003560832461625_161810111861.0RegionNote=Triple-helical region


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Fusion Gene Sequence for PDZD2-COL27A1


check button For in-frame fusion transcripts, we provide the fusion transcript sequences and fusion amino acid sequences. To have fusion amino acid sequence, we ran ORFfinder and chose the longest ORF among the all predicted ones.
>64139_64139_1_PDZD2-COL27A1_PDZD2_chr5_32093130_ENST00000282493_COL27A1_chr9_117014873_ENST00000356083_length(transcript)=12536nt_BP=8170nt
GCTGGAGGGATCCTCCATTCCTGTGTCATTTGCATGGGTCCTGCTGTGAAATGAACCTGGCAGGGACTTGTTAGACACTTCCTTCCTTCC
CTCATTGAGCACTCCAGTGCCATTGTTCCACAGTTGTTCTAATTGGGTCCTAGCTTCCTCCTGCCAAGGCAAACAGCATAGTCTCGAGTA
GGTGTCCCTAGGCTCATCTGCCAGCCTGAACATGAACACAGGCAAAGCTGATGATGGCCAGGGACCCCAGGGGACGTGGGGCCCTGTGGG
GTCTGGCCCCCAGGAGCAAGACCTCTGATGATGCTGGTGTCTGGGAGTGAGCACCATGCCCATCACCCAGGACAATGCCGTGCTGCACCT
GCCCCTCCTCTACCAGTGGCTGCAGAACAGCCTGCAGGAAGGTGGGGATGGGCCGGAGCAGCGGCTCTGCCAGGCGGCCATCCAGAAGCT
GCAGGAGTACATCCAGCTGAACTTTGCTGTGGATGAGAGTACGGTCCCACCTGATCACAGCCCCCCCGAAATGGAGATCTGTACTGTGTA
CCTCACCAAGGAGCTGGGGGACACAGAGACTGTGGGCCTGAGTTTTGGGAACATCCCTGTTTTCGGGGACTATGGTGAAAAGCGCAGGGG
GGGCAAGAAGAGGAAAACCCACCAGGGTCCTGTGCTGGATGTGGGCTGCATCTGGGTGACAGAGCTGAGGAAGAACAGCCCAGCAGGGAA
GAGTGGGAAGGTCCGACTGCGGGATGAGATCCTCTCACTGAATGGGCAGCTGATGGTTGGAGTTGATGTCAGTGGGGCCAGTTACCTGGC
TGAGCAGTGCTGGAATGGCGGCTTTATCTACCTGATCATGCTGCGTCGCTTTAAGCACAAAGCCCACTCCACTTATAATGGCAACAGTAG
CAACAGCTCTGAACCAGGAGAAACACCTACCTTGGAGCTGGGTGACCGAACTGCGAAAAAGGGGAAACGAACCAGAAAGTTTGGGGTCAT
CTCCAGGCCTCCTGCCAACAAGGCCCCTGAAGAATCCAAGGGCAGCGCTGGCTGTGAGGTGTCCAGTGACCCCAGCACTGAGCTGGAGAA
CGGCCCTGACCCTGAACTTGGAAACGGCCATGTCTTTCAGCTAGAAAATGGCCCAGATTCTCTCAAGGAGGTGGCTGGACCCCATCTAGA
GAGGTCAGAAGTGGACAGAGGGACAGAGCATAGAATTCCAAAGACAGATGCTCCTCTGACCACAAGCAATGACAAACGCCGCTTCTCAAA
AGGTGGGAAGACGGACTTCCAATCGAGTGACTGCCTGGCACGGGAGGAAGTTGGCCGAATATGGAAGATGGAGCTGCTCAAAGAATCGGA
TGGGCTGGGAATTCAGGTTAGTGGAGGCCGAGGATCAAAGCGCTCACCTCACGCTATCGTTGTCACTCAAGTGAAGGAAGGAGGTGCCGC
TCACAGGGATGGCAGGCTGTCCTTAGGAGATGAGCTGCTGGTAATCAATGGTCATTTACTGGTCGGGCTCTCCCACGAGGAAGCAGTGGC
CATTCTTCGCTCCGCCACGGGAATGGTGCAGCTTGTGGTGGCCAGCAAGGAAAACTCCGCAGAGGACCTCCTCAGGTTAACATCTAAGAG
CTTGCCAGATCTGACCAGCTCGGTAGAAGATGTGTCCTCCTGGACTGATAACGAAGACCAGGAGGCAGACGGGGAAGAGGACGAAGGAAC
CAGCTCTTCTGTCCAGAGAGCAATGCCTGGGACAGATGAACCCCAAGATGTGTGCGGTGCTGAGGAATCCAAGGGGAACTTGGAAAGTCC
CAAACAGGGCAGCAATAAAATCAAGCTCAAGAGTCGCCTTTCAGGGGGTGTACACCGCCTTGAGTCAGTTGAAGAATATAACGAGCTGAT
GGTGCGGAATGGGGACCCCCGGATCCGGATGTTGGAGGTCTCCCGAGATGGCCGGAAACACTCCCTCCCGCAGCTGCTGGACTCTTCCAG
TGCCTCACAGGAATACCACATTGTGAAGAAGTCTACCCGCTCCTTAAGCACGACTCAGGTGGAATCTCCTTGGAGGCTCATTCGGCCATC
CGTCATCTCGATCATTGGGTTGTACAAAGAAAAAGGCAAGGGCCTTGGCTTTAGTATTGCTGGAGGTCGAGACTGCATTCGTGGACAGAT
GGGGATTTTTGTCAAGACCATCTTCCCAAATGGATCAGCTGCAGAGGACGGAAGACTTAAAGAAGGGGATGAAATCCTAGATGTAAATGG
AATACCAATAAAGGGCTTGACATTTCAAGAAGCCATTCATACCTTTAAGCAAATCCGGAGTGGATTATTTGTTTTAACGGTACGCACAAA
GTTGGTGAGCCCCAGCCTCACACCCTGCTCGACACCCACACACATGAGCAGATCCGCCTCCCCGAACTTCAATACCAGTGGGGGAGCCTC
AGCGGGAGGTTCCGATGAAGGCAGTTCTTCATCCCTGGGTCGGAAGACCCCTGGGCCCAAGGACAGGATCGTCATGGAAGTAACACTCAA
CAAAGAGCCAAGAGTTGGATTAGGCATTGGTGCCTGCTGCTTGGCTCTGGAAAACAGTCCTCCTGGCATCTACATTCACAGCCTTGCTCC
AGGATCAGTGGCCAAGATGGAGAGCAACCTGAGCCGCGGGGATCAAATCCTGGAAGTGAACTCCGTCAACGTCCGCCATGCTGCTTTAAG
CAAAGTCCACGCCATCTTGAGTAAATGCCCTCCAGGACCCGTTCGCCTTGTCATCGGCCGGCACCCTAATCCAAAGGTTTCCGAGCAGGA
AATGGATGAAGTCATAGCACGCAGCACTTATCAGGAGAGCAAAGAGGCCAATTCCTCTCCTGGCTTAGGTACCCCCTTGAAGAGTCCCTC
TCTTGCAAAAAAGGACTCCCTTATTTCTGAATCTGAACTCTCCCAGTACTTTGCCCACGATGTCCCTGGCCCCTTGTCAGACTTCATGGT
GGCCGGTTCTGAGGACGAGGATCACCCGGGAAGTGGCTGCAGCACGTCGGAGGAGGGCAGCCTGCCTCCCAGCACCTCCACTCACAAGGA
GCCTGGAAAACCCAGAGCCAACAGCCTCGTGACTCTTGGGAGCCATCGGGCTTCTGGGCTCTTCCACAAGCAGGTGACAGTTGCCAGACA
AGCCAGTCTCCCCGGAAGCCCACAGGCCCTCCGAAACCCTCTCCTCCGCCAGAGGAAGGTAGGCTGCTACGATGCCAACGATGCCAGTGA
TGAGGAAGAGTTTGACAGAGAAGGGGACTGCATTTCACTCCCAGGGGCCCTCCCGGGTCCCATCAGGCCTCTGTCAGAGGATGACCCGAG
GCGTGTCTCAATTTCCTCTTCCAAGGGCATGGACGTCCACAACCAAGAGGAACGACCCCGGAAAACACTGGTGAGCAAGGCCATCTCGGC
ACCTCTTCTTGGTAGCTCAGTGGACTTAGAGGAGAGTATCCCAGAGGGCATGGTGGATGCTGCGTCCTATGCAGCCAACCTCACGGACTC
TGCAGAGGCCCCCAAGGGGAGCCCTGGAAGCTGGTGGAAGAAGGAACTGTCAGGATCAAGTAGCGCACCCAAATTGGAATACACAGTCCG
TACAGACACCCAGAGTCCGACGAACACTGGGAGCCCCAGTTCCCCCCAGCAGAAAAGTGAAGGCCTGGGCTCCAGGCACAGACCAGTGGC
CAGGGTAAGCCCCCACTGCAAGAGATCCGAGGCTGAGGCCAAGCCCAGTGGCTCACAGACAGTGAACCTGACTGGCAGAGCCAATGATCC
ATGCGATCTGGACTCGAGAGTCCAGGCCACTTCTGTCAAAGTGACTGTCGCTGGCTTTCAGCCAGGTGGAGCTGTGGAGAAGGAATCTCT
GGGAAAGCTGACCACTGGAGATGCTTGTGTCTCTACCAGCTGTGAACTAGCCAGTGCTCTGTCCCATCTGGATGCCAGCCACCTCACAGA
GAACCTGCCCAAAGCTGCATCAGAGCTGGGGCAACAACCCATGACTGAACTGGACAGCTCCTCAGACCTCATCTCTTCCCCAGGGAAGAA
GGGGGCCGCTCATCCTGACCCCAGCAAGACCTCTGTAGACACAGGGCAAGTCAGTCGGCCAGAGAATCCCAGCCAGCCTGCATCGCCCAG
GGTCACCAAGTGCAAGGCCAGGTCTCCAGTCAGGCTCCCCCATGAGGGCAGCCCCTCCCCGGGGGAGAAAGCAGCGGCTCCCCCTGACTA
CAGCAAGACTCGATCAGCATCGGAAACCAGCACACCCCACAATACCAGGAGGGTGGCTGCCCTCAGGGGAGCGGGACCTGGAGCAGAGGG
AATGACACCAGCTGGTGCTGTCCTGCCAGGAGACCCCCTCACATCCCAGGAGCAGAGACAGGGAGCTCCAGGTAACCACAGTAAGGCTCT
GGAAATGACAGGAATCCATGCACCTGAAAGCTCCCAGGAGCCTTCCCTGCTGGAGGGAGCAGATTCTGTGTCCTCAAGGGCACCGCAGGC
CAGCCTCTCCATGCTGCCATCCACTGACAACACCAAAGAAGCATGTGGCCATGTCTCGGGGCACTGCTGCCCAGGGGGGAGTAGAGAGAG
CCCTGTGACGGACATTGACAGCTTCATCAAGGAGCTGGATGCTTCTGCAGCAAGGTCTCCGTCTTCCCAGACGGGGGACAGTGGCTCTCA
GGAGGGCAGTGCTCAGGGCCACCCACCAGCCGGGGCTGGAGGTGGGAGCTCCTGCCGTGCCGAACCAGTCCCGGGGGGCCAGACCTCCTC
CCCGAGGAGGGCCTGGGCTGCTGGTGCCCCCGCCTACCCACAATGGGCCTCCCAGCCTTCGGTTTTAGATTCAATTAATCCCGACAAACA
TTTTACTGTGAACAAAAACTTTCTGAGCAACTACTCTAGAAATTTTAGCAGTTTTCATGAAGACAGCACCTCCCTATCAGGCCTGGGTGA
CAGCACGGAGCCGTCTCTGTCATCCATGTATGGCGATGCTGAGGATTCTTCTTCTGACCCTGAGTCACTCACTGAAGCCCCACGAGCTTC
TGCCAGGGACGGCTGGTCCCCTCCTCGTTCCCGTGTGTCTTTGCACAAGGAAGATCCTTCGGAGTCAGAAGAGGAACAGATTGAGATTTG
TTCCACACGTGGCTGCCCCAATCCACCCTCGAGTCCTGCTCATCTTCCCACCCAGGCTGCCATCTGTCCTGCCTCAGCCAAAGTTCTGTC
ATTAAAATACAGCACTCCGAGAGAGTCGGTGGCCAGTCCCCGTGAGAAGGCCGCCTGCTTGCCAGGCTCATACACTTCAGGCCCAGACTC
TTCCCAGCCATCATCACTCTTGGAGATGAGCTCTCAGGAGCATGAAACTCATGCGGACATAAGCACTTCACAGAACCACAGGCCCTCGTG
TGCAGAAGAAACCACAGAAGTCACCAGCGCTAGCTCAGCCATGGAAAACAGTCCGCTGTCTAAAGTAGCCAGGCATTTTCACAGTCCGCC
CATCATTCTCAGCTCCCCCAACATGGTAAATGGCTTGGAACATGACCTGCTAGATGACGAAACCCTGAATCAATACGAAACAAGCATTAA
TGCAGCTGCCAGTCTGTCCTCCTTCAGTGTGGATGTCCCTAAGAATGGAGAATCTGTTTTGGAAAACCTCCACATCTCTGAAAGTCAAGA
CCTGGATGACTTGCTACAGAAACCAAAAATGATCGCTAGGAGGCCCATCATGGCCTGGTTTAAAGAAATAAATAAACATAACCAAGGCAC
ACATTTGAGGAGCAAAACCGAGAAGGAACAACCTCTAATGCCTGCCAGAAGTCCCGACTCCAAGATTCAGATGGTGAGTTCAAGCCAAAA
AAAGGGCGTTACTGTGCCTCATAGCCCTCCTCAGCCGAAAACAAACCTGGAAAATAAGGACCTGTCTAAGAAGAGTCCGGCAGAAATGCT
TCTGACTAATGGTCAGAAGGCAAAGTGTGGTCCGAAGCTGAAGAGGCTCAGCCTCAAGGGCAAGGCCAAAGTCAACTCTGAGGCCCCTGC
TGCGAATGCTGTGAAGGCTGGGGGGACGGACCACAGGAAACCCTTGATCTCACCCCAGACCTCCCACAAAACACTTTCTAAGGCAGTGTC
ACAGCGGCTCCATGTAGCCGACCACGAGGACCCTGACAGAAACACCACAGCTGCCCCCAGGTCCCCCCAGTGTGTGCTGGAAAGCAAGCC
ACCTCTTGCCACCTCTGGGCCACTGAAACCCTCAGTGTCTGACACGAGCATCAGGACATTTGTCTCGCCCCTGACCTCTCCCAAGCCTGT
TCCTGAGCAAGGCATGTGGAGCAGGTTCCACATGGCTGTCCTCTCTGAACCCGACAGAGGTTGCCCAACCACCCCTAAATCTCCTAAGTG
TAGAGCAGAGGGCAGGGCGCCCCGTGCTGACTCCGGGCCGGTGAGTCCGGCAGCGTCTAGGAACGGCATGTCCGTGGCAGGGAACAGACA
GAGTGAGCCGCGCCTGGCCAGCCATGTGGCAGCAGACACAGCCCAACCCAGGCCGACTGGCGAAAAAGGAGGCAACATAATGGCCAGCGA
TCGCCTCGAAAGAACAAACCAGCTGAAAATCGTGGAGATTTCTGCTGAAGCAGTGTCAGAGACTGTATGTGGTAACAAGCCAGCTGAAAG
CGACAGACGGGGAGGGTGCTTGGCCCAGGGCAACTGTCAGGAGAAGAGTGAAATCAGGCTCTATCGCCAGGTCGCAGAATCATCCACAAG
TCATCCATCCTCACTCCCATCTCATGCCTCCCAGGCAGAGCAGGAAATGTCACGATCATTCAGCATGGCAAAACTGGCGTCCTCCTCCTC
CTCCCTTCAAACAGCCATTAGAAAGGCAGAATACTCCCAGGGAAAATCAAGCCTGATGTCAGACTCCCGAGGGGTGCCCAGAAACAGCAT
TCCAGGGGGCCCCTCGGGGGAGGACCATCTCTACTTCACCCCAAGGCCAGCGACCAGGACCTACTCCATGCCAGCCCAGTTCTCAAGCCA
TTTTGGACGGGAGGGTCACCCCCCACACAGCCTGGGTCGCTCTCGGGACAGCCAGGTCCCTGTGACAAGCAGTGTTGTCCCCGAGGCAAA
GGCATCCAGAGGTGGTCTTCCCAGCCTGGCTAATGGACAGGGCATATATAGTGTAAAGCCGCTGCTGGACACATCGAGGAATCTTCCAGC
CACAGATGAAGGGGATATCATTTCAGTCCAGGAGACGAGCTGCCTAGTCACAGACAAAATCAAAGTCACCAGACGACACTACTGCTATGA
GCAGAACTGGCCCCATGAATCTACCTCATTTTTCTCTGTGAAGCAGCGGATCAAGTCTTTTGAGAACCTGGCCAATGCTGACCGGCCTGT
AGCCAAGTCCGGGGCTTCCCCATTTTTGTCGGTGAGCTCCAAGCCTCCCATTGGGAGGCGGTCTTCCGGCAGCATTGTTTCCGGGAGCCT
GGGCCACCCAGGTGACGCAGCAGCAAGGTTGTTGAGACGCAGCTTGAGTTCCTGCAGCGAAAACCAAAGCGAAGCCGGCACCCTCCTGCC
CCAGATGGCCAAGTCTCCCTCAATCATGACACTGACCATCTCTCGGCAGAACCCACCAGAGACCAGTAGCAAGGGCTCTGATTCGGAACT
AAAGAAATCACTTGGTCCTTTGGGAATTCCCACCCCAACGATGACCCTGGCTTCTCCTGTTAAGAGGAACAAGTCCTCGGTACGCCACAC
GCAGCCCTCGCCCGTGTCCCGCTCCAAGCTCCAGGAGCTGAGAGCCTTGAGCATGCCTGACCTTGACAAGCTCTGCAGCGAGGATTACTC
AGCAGGGCCGAGCGCCGTGCTCTTCAAAACTGAGCTGGAGATCACCCCCAGGAGGTCACCTGGCCCTCCTGCTGGAGGCGTTTCGTGTCC
CGAGAAGGGCGGGAACAGGGCCTGTCCAGGAGGAAGTGGCCCTAAAACCAGTGCTGCTGAGACACCCAGTTCAGCCAGTGATACGGGTGA
AGCTGCCCAGGATCTGCCTTTTAGAAGAAGCTGGTCAGTTAATTTGGATCAACTTCTAGTCTCAGCGGGGGACCAGCAAAGATTACAGTC
TGTTTTATCGTCAGTGGGATCGAAATCTACCATCCTAACTCTCATTCAGGAAGCGAAAGCACAATCAGAGGGTGATCGTGGCATGATGGG
ACCCCCAGGCGTGCCTGGACCCAAGGGGTCGATGGGTCATCCTGGAATGCCAGGTGGTATGGGGACCCCTGGAGAGCCTGGACCCCAGGG
TCCTCCAGGATCTCGAGGCCCACCAGGCATGAGGGGAGCAAAGGGACGTCGGGGCCCCCGAGGACCGGACGGACCAGCTGGGGAGCAAGG
GTCCAGGGGCCTGAAGGGCCCTCCAGGACCCCAGGGCAGACCGGGCCGGCCTGGACAGCAGGGTGTGGCTGGTGAGCGAGGCCACTTGGG
CTCGAGAGGCTTTCCTGGCATCCCGGGTCCCTCAGGCCCCCCAGGCACCAAGGGCCTCCCAGGAGAACCGGGCCCTCAGGGACCCCAGGG
GCCAATTGGGCCTCCAGGAGAGATGGGACCCAAGGGGCCGCCTGGTGCAGTGGGAGAACCGGGCCTTCCTGGGGAAGCCGGGATGAAGGG
TGACCTTGGACCCCTGGGCACTCCTGGGGAGCAGGGCCTCATTGGGCAACGGGGAGAGCCAGGCCTTGAGGGTGACAGTGGCCCCATGGG
ACCTGATGGGCTGAAGGGGGACAGGGGAGACCCAGGGCCTGATGGAGAACATGGCGAGAAAGGCCAGGAAGGGCTGATGGGTGAGGACGG
GCCCCCCGGCCCCCCTGGCGTCACTGGTGTCCGGGGTCCTGAAGGAAAATCAGGGAAGCAAGGCGAGAAGGGCCGCACTGGAGCCAAGGG
TGCCAAGGGCTATCAAGGACAGCTGGGTGAGATGGGCGTCCCTGGAGACCCTGGACCCCCTGGCACTCCAGGCCCTAAAGGGTCCCGGGG
CAGCCTGGGACCAACGGGTGCTCCGGGACGCATGGGGGCCCAAGGAGAACCGGGACTGGCTGGTTATGATGGACACAAAGGCATTGTGGG
ACCCCTTGGACCTCCTGGACCAAAAGGCGAAAAGGGGGAGCAGGGCGAGGACGGCAAGGCTGAGGGGCCCCCTGGGCCACCTGGAGATCG
GGGCCCTGTGGGTGATCGAGGAGACCGCGGGGAACCGGGAGACCCTGGGTACCCTGGACAGGAGGGTGTGCAAGGCCTCCGTGGAAAGCC
AGGCCAGCAGGGCCAACCCGGGCATCCGGGACCCCGGGGGTGGCCGGGACCCAAAGGATCGAAAGGCGCAGAGGGACCAAAGGGAAAGCA
AGGCAAGGCAGGGGCCCCAGGCCGGAGGGGGGTCCAGGGCCTGCAGGGGCTGCCAGGGCCCCGGGGCGTGGTGGGGAGACAGGGCCTCGA
GGGCATCGCTGGACCAGATGGGCTTCCTGGCAGGGACGGGCAAGCAGGACAGCAGGGGGAGCAGGGAGACGATGGGGACCCTGGCCCCAT
GGGCCCTGCTGGGAAGAGAGGAAATCCAGGTGTGGCCGGCTTACCTGGAGCACAGGGACCCCCAGGATTCAAGGGTGAGAGTGGGTTACC
CGGACAGCTGGGTCCCCCTGGCAAGCGAGGAACAGAGGGCAGAACGGGGCTCCCTGGAAACCAGGGGGAGCCTGGGTCCAAAGGCCAGCC
GGGCGACTCTGGCGAGATGGGCTTCCCAGGAATGGCAGGTCTCTTCGGACCCAAGGGCCCGCCTGGAGACATTGGCTTCAAAGGCATCCA
GGGCCCTCGGGGGCCACCTGGCTTGATGGGAAAGGAAGGCATCGTCGGGCCCCTCGGAATCCTGGGACCTTCGGGACTCCCGGGTCCGAA
GGGTGACAAAGGCAGCCGTGGGGACTGGGGATTGCAAGGTCCGAGGGGTCCTCCCGGCCCCAGAGGGCGGCCCGGCCCCCCGGGTCCTCC
AGGGGGTCCTATCCAATTGCAACAAGATGATCTTGGGGCAGCTTTCCAGACGTGGATGGACACCAGTGGAGCACTCAGGCCAGAGAGTTA
CAGCTATCCAGACCGGCTGGTGCTGGACCAGGGAGGAGAGATCTTTAAAACCTTACACTACCTCAGCAACCTCATCCAGAGCATTAAGAC
GCCCCTGGGCACCAAAGAGAACCCCGCCCGGGTCTGCAGGGACCTCATGGACTGTGAGCAGAAGATGGTGGATGGTACCTACTGGGTGGA
TCCAAACCTTGGCTGCTCCTCTGACACCATCGAGGTCTCCTGCAACTTCACTCATGGTGGACAGACGTGTCTCAAGCCCATCACGGCCTC
CAAGGTCGAGTTTGCCATCAGCCGGGTCCAGATGAATTTCCTGCACCTGCTAAGCTCCGAGGTGACCCAGCACATCACCATCCACTGCCT
TAACATGACCGTGTGGCAGGAGGGCACTGGGCAGACCCCAGCCAAGCAGGCCGTACGCTTCCGGGCCTGGAATGGACAGATTTTTGAAGC
TGGGGGTCAGTTCCGGCCCGAGGTGTCCATGGATGGCTGCAAGGTCCAAGATGGCCGCTGGCATCAGACACTCTTCACCTTCCGGACCCA
AGACCCCCAACAGCTGCCCATCATCAGTGTGGACAACCTCCCTCCTGCCTCATCAGGGAAGCAGTACCGCCTGGAAGTTGGACCTGCGTG
CTTCCTCTGACCTCTGACCTCGTGGCCACTCTAGGCCTCACGGAGGAGGGAAGAGGAAGAGGCAAGGGGAGGGTACTGAGGGGCAGATGG
CTCCAGGAGAGGCAGCTCCCCTGCCCAAGGGTCCTTGGGCAGACCCCAGCTGTTGTCTGCCCAGTAGAAGTGGGTGGGGGTAGGAGGGGA
TAGGGTGTCCTTGGGAACAATGGATCCCAGCTTAGCCCCAAAGACCAACCAAAGAGCCAGCCAGAGTAAGCTGGACCTGCAACCTGCCTG
AGCCCCGTGGCCTCTCAGCTCTGCGGCCACCCCGTTCCCTCCCCAGCTTCCTGCCCAAAGAGCCCCACATTCAAGCCAACTTGAGGGAAG
GGGGCGTCTCGTCAGCTGGTCCCTGCTAGGGAGCTATTGATGTGCAATATTAGAAAGGAGACATGAAAAAAGGAGAAAAGGAAAGACAGA
AGTGTATATATATATTATTTAAACAAACAAAAAGAAGGTGCGTTACTATTTTTTTTTCACCCGGGAAAGAGGTGAGAGGATGGGAAGGAG
CAGCCAGGCGTGGGAAGCGGCGAGATCCTCGGGCTGGGGGTGCCCACGTTTGCTACCTCCCACTGTGAAATCGCTGGTGCTCACAATTGT
CTCTCACAGTGTATGTGATTTTTTTAAGGAAAAAAAAAAATCCCTATTTAAGATTCTGAAGGTGCTACCATTATTTTGCCACAGACTTTG
AAGAAACTTTTGGATGTGGGGCATCATCCGCATCTTTCTCTCTCCTCCAAATGACAAAGTTTGGGGAATTTTTGAATTTTCCTAGCATCG
CCCTTGTGCTCATCAGGTAATCTGCTAAGGAGGAAAAAAGAAAAGAAAAAAGGAAAAAAAAAAAAAAAAAGCAAAACAAAAACAAAAACA
AAAACCCTACCAGAAACCAGAAGTAGAGAGATTTACCATATAACTTATGGACTTTGAAATGTCTGTCCTTTTAAGGCAGCAGGGAGGCCT
GGGTGCGAAGCATGTTGGCTTGGCCCTTCACGGTCCTGGAGGGAGGTGAGGCTGGCCTTGGAAGGCGTGCCCTGGAGAGGTCTTGGGTGA
AAACTTGACCTTGAAGAAACCAATCACAAAAGCGGCGTTGGGTCAGGGCTAGGCTTAGAGGTGAAGCATCAACATGGAACCATCTCAGGA
AGCCGCATCGCCTCTTCCGAGGTCCTCACTTCCAGGAGCCTGTCCTTGCAAGATGCAATCATCGTTCCTGCTTTTTCATTGTCATTAAAT
TCTGTAGAAACCCATTGTCATTAGCTCCAAGTGTAAATTTGGGTCAAGGAGACAGAATAATAATGGGAATCTCGGAGTTCGACACCATAG
TGACGTTCAGCGTCCTCTGAATTGTGCTACATCAGCGAACAAGTCGGCGCTTGAATTGGATTTTGAGGTTATTTTAACCATGGAATTATT
TTTATAGAAGGGGAAAATGTATGTGAAAGTCTCTATTTGTGTATTTCTCTCCTAAAGTTGTGTCTCTTTGGGAATTGGATTTGATTTTTA
TTATTTAATACCTCACTTTGGCCCGTCCCCCCTCCCAACACTTCTGTATCCTCGCCCTGCCGCCCCAGCCTGGACGCTCTGCGTGGAAGT
GCGTGTTTGTAGCAGCTCGGGCCTCATCTCAGCGCTCGGATCCCTCCTGCTGCCAGAATCCACTGGCCTCTGTCTCATTCTTGGGTTTTC
CTGCTGTCTTCGTTTACGTCTCTGTCCACATGTCAGTGTATTAAAACCCCAATGGGTTCCGTTTCTCCTTTTCCCCTCTGGATTTTAAAT

>64139_64139_1_PDZD2-COL27A1_PDZD2_chr5_32093130_ENST00000282493_COL27A1_chr9_117014873_ENST00000356083_length(amino acids)=3469AA_BP=2758
MGVSTMPITQDNAVLHLPLLYQWLQNSLQEGGDGPEQRLCQAAIQKLQEYIQLNFAVDESTVPPDHSPPEMEICTVYLTKELGDTETVGL
SFGNIPVFGDYGEKRRGGKKRKTHQGPVLDVGCIWVTELRKNSPAGKSGKVRLRDEILSLNGQLMVGVDVSGASYLAEQCWNGGFIYLIM
LRRFKHKAHSTYNGNSSNSSEPGETPTLELGDRTAKKGKRTRKFGVISRPPANKAPEESKGSAGCEVSSDPSTELENGPDPELGNGHVFQ
LENGPDSLKEVAGPHLERSEVDRGTEHRIPKTDAPLTTSNDKRRFSKGGKTDFQSSDCLAREEVGRIWKMELLKESDGLGIQVSGGRGSK
RSPHAIVVTQVKEGGAAHRDGRLSLGDELLVINGHLLVGLSHEEAVAILRSATGMVQLVVASKENSAEDLLRLTSKSLPDLTSSVEDVSS
WTDNEDQEADGEEDEGTSSSVQRAMPGTDEPQDVCGAEESKGNLESPKQGSNKIKLKSRLSGGVHRLESVEEYNELMVRNGDPRIRMLEV
SRDGRKHSLPQLLDSSSASQEYHIVKKSTRSLSTTQVESPWRLIRPSVISIIGLYKEKGKGLGFSIAGGRDCIRGQMGIFVKTIFPNGSA
AEDGRLKEGDEILDVNGIPIKGLTFQEAIHTFKQIRSGLFVLTVRTKLVSPSLTPCSTPTHMSRSASPNFNTSGGASAGGSDEGSSSSLG
RKTPGPKDRIVMEVTLNKEPRVGLGIGACCLALENSPPGIYIHSLAPGSVAKMESNLSRGDQILEVNSVNVRHAALSKVHAILSKCPPGP
VRLVIGRHPNPKVSEQEMDEVIARSTYQESKEANSSPGLGTPLKSPSLAKKDSLISESELSQYFAHDVPGPLSDFMVAGSEDEDHPGSGC
STSEEGSLPPSTSTHKEPGKPRANSLVTLGSHRASGLFHKQVTVARQASLPGSPQALRNPLLRQRKVGCYDANDASDEEEFDREGDCISL
PGALPGPIRPLSEDDPRRVSISSSKGMDVHNQEERPRKTLVSKAISAPLLGSSVDLEESIPEGMVDAASYAANLTDSAEAPKGSPGSWWK
KELSGSSSAPKLEYTVRTDTQSPTNTGSPSSPQQKSEGLGSRHRPVARVSPHCKRSEAEAKPSGSQTVNLTGRANDPCDLDSRVQATSVK
VTVAGFQPGGAVEKESLGKLTTGDACVSTSCELASALSHLDASHLTENLPKAASELGQQPMTELDSSSDLISSPGKKGAAHPDPSKTSVD
TGQVSRPENPSQPASPRVTKCKARSPVRLPHEGSPSPGEKAAAPPDYSKTRSASETSTPHNTRRVAALRGAGPGAEGMTPAGAVLPGDPL
TSQEQRQGAPGNHSKALEMTGIHAPESSQEPSLLEGADSVSSRAPQASLSMLPSTDNTKEACGHVSGHCCPGGSRESPVTDIDSFIKELD
ASAARSPSSQTGDSGSQEGSAQGHPPAGAGGGSSCRAEPVPGGQTSSPRRAWAAGAPAYPQWASQPSVLDSINPDKHFTVNKNFLSNYSR
NFSSFHEDSTSLSGLGDSTEPSLSSMYGDAEDSSSDPESLTEAPRASARDGWSPPRSRVSLHKEDPSESEEEQIEICSTRGCPNPPSSPA
HLPTQAAICPASAKVLSLKYSTPRESVASPREKAACLPGSYTSGPDSSQPSSLLEMSSQEHETHADISTSQNHRPSCAEETTEVTSASSA
MENSPLSKVARHFHSPPIILSSPNMVNGLEHDLLDDETLNQYETSINAAASLSSFSVDVPKNGESVLENLHISESQDLDDLLQKPKMIAR
RPIMAWFKEINKHNQGTHLRSKTEKEQPLMPARSPDSKIQMVSSSQKKGVTVPHSPPQPKTNLENKDLSKKSPAEMLLTNGQKAKCGPKL
KRLSLKGKAKVNSEAPAANAVKAGGTDHRKPLISPQTSHKTLSKAVSQRLHVADHEDPDRNTTAAPRSPQCVLESKPPLATSGPLKPSVS
DTSIRTFVSPLTSPKPVPEQGMWSRFHMAVLSEPDRGCPTTPKSPKCRAEGRAPRADSGPVSPAASRNGMSVAGNRQSEPRLASHVAADT
AQPRPTGEKGGNIMASDRLERTNQLKIVEISAEAVSETVCGNKPAESDRRGGCLAQGNCQEKSEIRLYRQVAESSTSHPSSLPSHASQAE
QEMSRSFSMAKLASSSSSLQTAIRKAEYSQGKSSLMSDSRGVPRNSIPGGPSGEDHLYFTPRPATRTYSMPAQFSSHFGREGHPPHSLGR
SRDSQVPVTSSVVPEAKASRGGLPSLANGQGIYSVKPLLDTSRNLPATDEGDIISVQETSCLVTDKIKVTRRHYCYEQNWPHESTSFFSV
KQRIKSFENLANADRPVAKSGASPFLSVSSKPPIGRRSSGSIVSGSLGHPGDAAARLLRRSLSSCSENQSEAGTLLPQMAKSPSIMTLTI
SRQNPPETSSKGSDSELKKSLGPLGIPTPTMTLASPVKRNKSSVRHTQPSPVSRSKLQELRALSMPDLDKLCSEDYSAGPSAVLFKTELE
ITPRRSPGPPAGGVSCPEKGGNRACPGGSGPKTSAAETPSSASDTGEAAQDLPFRRSWSVNLDQLLVSAGDQQRLQSVLSSVGSKSTILT
LIQEAKAQSEGDRGMMGPPGVPGPKGSMGHPGMPGGMGTPGEPGPQGPPGSRGPPGMRGAKGRRGPRGPDGPAGEQGSRGLKGPPGPQGR
PGRPGQQGVAGERGHLGSRGFPGIPGPSGPPGTKGLPGEPGPQGPQGPIGPPGEMGPKGPPGAVGEPGLPGEAGMKGDLGPLGTPGEQGL
IGQRGEPGLEGDSGPMGPDGLKGDRGDPGPDGEHGEKGQEGLMGEDGPPGPPGVTGVRGPEGKSGKQGEKGRTGAKGAKGYQGQLGEMGV
PGDPGPPGTPGPKGSRGSLGPTGAPGRMGAQGEPGLAGYDGHKGIVGPLGPPGPKGEKGEQGEDGKAEGPPGPPGDRGPVGDRGDRGEPG
DPGYPGQEGVQGLRGKPGQQGQPGHPGPRGWPGPKGSKGAEGPKGKQGKAGAPGRRGVQGLQGLPGPRGVVGRQGLEGIAGPDGLPGRDG
QAGQQGEQGDDGDPGPMGPAGKRGNPGVAGLPGAQGPPGFKGESGLPGQLGPPGKRGTEGRTGLPGNQGEPGSKGQPGDSGEMGFPGMAG
LFGPKGPPGDIGFKGIQGPRGPPGLMGKEGIVGPLGILGPSGLPGPKGDKGSRGDWGLQGPRGPPGPRGRPGPPGPPGGPIQLQQDDLGA
AFQTWMDTSGALRPESYSYPDRLVLDQGGEIFKTLHYLSNLIQSIKTPLGTKENPARVCRDLMDCEQKMVDGTYWVDPNLGCSSDTIEVS
CNFTHGGQTCLKPITASKVEFAISRVQMNFLHLLSSEVTQHITIHCLNMTVWQEGTGQTPAKQAVRFRAWNGQIFEAGGQFRPEVSMDGC

--------------------------------------------------------------
>64139_64139_2_PDZD2-COL27A1_PDZD2_chr5_32093130_ENST00000438447_COL27A1_chr9_117014873_ENST00000356083_length(transcript)=12599nt_BP=8233nt
GCGGGAGCCTCGGCCAAGCCGCGAGCAGGTGTGAATGAGCCCAGGGAAGGACACACGGCCACTGCTGGAGGGATCCTCCATTCCTGTGTC
ATTTGCATGGGTCCTGCTGTGAAATGAACCTGGCAGGGACTTGTTAGACACTTCCTTCCTTCCCTCATTGAGCACTCCAGTGCCATTGTT
CCACAGTTGTTCTAATTGGGTCCTAGCTTCCTCCTGCCAAGGCAAACAGCATAGTCTCGAGTAGGTGTCCCTAGGCTCATCTGCCAGCCT
GAACATGAACACAGGCAAAGCTGATGATGGCCAGGGACCCCAGGGGACGTGGGGCCCTGTGGGGTCTGGCCCCCAGGAGCAAGACCTCTG
ATGATGCTGGTGTCTGGGAGTGAGCACCATGCCCATCACCCAGGACAATGCCGTGCTGCACCTGCCCCTCCTCTACCAGTGGCTGCAGAA
CAGCCTGCAGGAAGGTGGGGATGGGCCGGAGCAGCGGCTCTGCCAGGCGGCCATCCAGAAGCTGCAGGAGTACATCCAGCTGAACTTTGC
TGTGGATGAGAGTACGGTCCCACCTGATCACAGCCCCCCCGAAATGGAGATCTGTACTGTGTACCTCACCAAGGAGCTGGGGGACACAGA
GACTGTGGGCCTGAGTTTTGGGAACATCCCTGTTTTCGGGGACTATGGTGAAAAGCGCAGGGGGGGCAAGAAGAGGAAAACCCACCAGGG
TCCTGTGCTGGATGTGGGCTGCATCTGGGTGACAGAGCTGAGGAAGAACAGCCCAGCAGGGAAGAGTGGGAAGGTCCGACTGCGGGATGA
GATCCTCTCACTGAATGGGCAGCTGATGGTTGGAGTTGATGTCAGTGGGGCCAGTTACCTGGCTGAGCAGTGCTGGAATGGCGGCTTTAT
CTACCTGATCATGCTGCGTCGCTTTAAGCACAAAGCCCACTCCACTTATAATGGCAACAGTAGCAACAGCTCTGAACCAGGAGAAACACC
TACCTTGGAGCTGGGTGACCGAACTGCGAAAAAGGGGAAACGAACCAGAAAGTTTGGGGTCATCTCCAGGCCTCCTGCCAACAAGGCCCC
TGAAGAATCCAAGGGCAGCGCTGGCTGTGAGGTGTCCAGTGACCCCAGCACTGAGCTGGAGAACGGCCCTGACCCTGAACTTGGAAACGG
CCATGTCTTTCAGCTAGAAAATGGCCCAGATTCTCTCAAGGAGGTGGCTGGACCCCATCTAGAGAGGTCAGAAGTGGACAGAGGGACAGA
GCATAGAATTCCAAAGACAGATGCTCCTCTGACCACAAGCAATGACAAACGCCGCTTCTCAAAAGGTGGGAAGACGGACTTCCAATCGAG
TGACTGCCTGGCACGGGAGGAAGTTGGCCGAATATGGAAGATGGAGCTGCTCAAAGAATCGGATGGGCTGGGAATTCAGGTTAGTGGAGG
CCGAGGATCAAAGCGCTCACCTCACGCTATCGTTGTCACTCAAGTGAAGGAAGGAGGTGCCGCTCACAGGGATGGCAGGCTGTCCTTAGG
AGATGAGCTGCTGGTAATCAATGGTCATTTACTGGTCGGGCTCTCCCACGAGGAAGCAGTGGCCATTCTTCGCTCCGCCACGGGAATGGT
GCAGCTTGTGGTGGCCAGCAAGGAAAACTCCGCAGAGGACCTCCTCAGGTTAACATCTAAGAGCTTGCCAGATCTGACCAGCTCGGTAGA
AGATGTGTCCTCCTGGACTGATAACGAAGACCAGGAGGCAGACGGGGAAGAGGACGAAGGAACCAGCTCTTCTGTCCAGAGAGCAATGCC
TGGGACAGATGAACCCCAAGATGTGTGCGGTGCTGAGGAATCCAAGGGGAACTTGGAAAGTCCCAAACAGGGCAGCAATAAAATCAAGCT
CAAGAGTCGCCTTTCAGGGGGTGTACACCGCCTTGAGTCAGTTGAAGAATATAACGAGCTGATGGTGCGGAATGGGGACCCCCGGATCCG
GATGTTGGAGGTCTCCCGAGATGGCCGGAAACACTCCCTCCCGCAGCTGCTGGACTCTTCCAGTGCCTCACAGGAATACCACATTGTGAA
GAAGTCTACCCGCTCCTTAAGCACGACTCAGGTGGAATCTCCTTGGAGGCTCATTCGGCCATCCGTCATCTCGATCATTGGGTTGTACAA
AGAAAAAGGCAAGGGCCTTGGCTTTAGTATTGCTGGAGGTCGAGACTGCATTCGTGGACAGATGGGGATTTTTGTCAAGACCATCTTCCC
AAATGGATCAGCTGCAGAGGACGGAAGACTTAAAGAAGGGGATGAAATCCTAGATGTAAATGGAATACCAATAAAGGGCTTGACATTTCA
AGAAGCCATTCATACCTTTAAGCAAATCCGGAGTGGATTATTTGTTTTAACGGTACGCACAAAGTTGGTGAGCCCCAGCCTCACACCCTG
CTCGACACCCACACACATGAGCAGATCCGCCTCCCCGAACTTCAATACCAGTGGGGGAGCCTCAGCGGGAGGTTCCGATGAAGGCAGTTC
TTCATCCCTGGGTCGGAAGACCCCTGGGCCCAAGGACAGGATCGTCATGGAAGTAACACTCAACAAAGAGCCAAGAGTTGGATTAGGCAT
TGGTGCCTGCTGCTTGGCTCTGGAAAACAGTCCTCCTGGCATCTACATTCACAGCCTTGCTCCAGGATCAGTGGCCAAGATGGAGAGCAA
CCTGAGCCGCGGGGATCAAATCCTGGAAGTGAACTCCGTCAACGTCCGCCATGCTGCTTTAAGCAAAGTCCACGCCATCTTGAGTAAATG
CCCTCCAGGACCCGTTCGCCTTGTCATCGGCCGGCACCCTAATCCAAAGGTTTCCGAGCAGGAAATGGATGAAGTCATAGCACGCAGCAC
TTATCAGGAGAGCAAAGAGGCCAATTCCTCTCCTGGCTTAGGTACCCCCTTGAAGAGTCCCTCTCTTGCAAAAAAGGACTCCCTTATTTC
TGAATCTGAACTCTCCCAGTACTTTGCCCACGATGTCCCTGGCCCCTTGTCAGACTTCATGGTGGCCGGTTCTGAGGACGAGGATCACCC
GGGAAGTGGCTGCAGCACGTCGGAGGAGGGCAGCCTGCCTCCCAGCACCTCCACTCACAAGGAGCCTGGAAAACCCAGAGCCAACAGCCT
CGTGACTCTTGGGAGCCATCGGGCTTCTGGGCTCTTCCACAAGCAGGTGACAGTTGCCAGACAAGCCAGTCTCCCCGGAAGCCCACAGGC
CCTCCGAAACCCTCTCCTCCGCCAGAGGAAGGTAGGCTGCTACGATGCCAACGATGCCAGTGATGAGGAAGAGTTTGACAGAGAAGGGGA
CTGCATTTCACTCCCAGGGGCCCTCCCGGGTCCCATCAGGCCTCTGTCAGAGGATGACCCGAGGCGTGTCTCAATTTCCTCTTCCAAGGG
CATGGACGTCCACAACCAAGAGGAACGACCCCGGAAAACACTGGTGAGCAAGGCCATCTCGGCACCTCTTCTTGGTAGCTCAGTGGACTT
AGAGGAGAGTATCCCAGAGGGCATGGTGGATGCTGCGTCCTATGCAGCCAACCTCACGGACTCTGCAGAGGCCCCCAAGGGGAGCCCTGG
AAGCTGGTGGAAGAAGGAACTGTCAGGATCAAGTAGCGCACCCAAATTGGAATACACAGTCCGTACAGACACCCAGAGTCCGACGAACAC
TGGGAGCCCCAGTTCCCCCCAGCAGAAAAGTGAAGGCCTGGGCTCCAGGCACAGACCAGTGGCCAGGGTAAGCCCCCACTGCAAGAGATC
CGAGGCTGAGGCCAAGCCCAGTGGCTCACAGACAGTGAACCTGACTGGCAGAGCCAATGATCCATGCGATCTGGACTCGAGAGTCCAGGC
CACTTCTGTCAAAGTGACTGTCGCTGGCTTTCAGCCAGGTGGAGCTGTGGAGAAGGAATCTCTGGGAAAGCTGACCACTGGAGATGCTTG
TGTCTCTACCAGCTGTGAACTAGCCAGTGCTCTGTCCCATCTGGATGCCAGCCACCTCACAGAGAACCTGCCCAAAGCTGCATCAGAGCT
GGGGCAACAACCCATGACTGAACTGGACAGCTCCTCAGACCTCATCTCTTCCCCAGGGAAGAAGGGGGCCGCTCATCCTGACCCCAGCAA
GACCTCTGTAGACACAGGGCAAGTCAGTCGGCCAGAGAATCCCAGCCAGCCTGCATCGCCCAGGGTCACCAAGTGCAAGGCCAGGTCTCC
AGTCAGGCTCCCCCATGAGGGCAGCCCCTCCCCGGGGGAGAAAGCAGCGGCTCCCCCTGACTACAGCAAGACTCGATCAGCATCGGAAAC
CAGCACACCCCACAATACCAGGAGGGTGGCTGCCCTCAGGGGAGCGGGACCTGGAGCAGAGGGAATGACACCAGCTGGTGCTGTCCTGCC
AGGAGACCCCCTCACATCCCAGGAGCAGAGACAGGGAGCTCCAGGTAACCACAGTAAGGCTCTGGAAATGACAGGAATCCATGCACCTGA
AAGCTCCCAGGAGCCTTCCCTGCTGGAGGGAGCAGATTCTGTGTCCTCAAGGGCACCGCAGGCCAGCCTCTCCATGCTGCCATCCACTGA
CAACACCAAAGAAGCATGTGGCCATGTCTCGGGGCACTGCTGCCCAGGGGGGAGTAGAGAGAGCCCTGTGACGGACATTGACAGCTTCAT
CAAGGAGCTGGATGCTTCTGCAGCAAGGTCTCCGTCTTCCCAGACGGGGGACAGTGGCTCTCAGGAGGGCAGTGCTCAGGGCCACCCACC
AGCCGGGGCTGGAGGTGGGAGCTCCTGCCGTGCCGAACCAGTCCCGGGGGGCCAGACCTCCTCCCCGAGGAGGGCCTGGGCTGCTGGTGC
CCCCGCCTACCCACAATGGGCCTCCCAGCCTTCGGTTTTAGATTCAATTAATCCCGACAAACATTTTACTGTGAACAAAAACTTTCTGAG
CAACTACTCTAGAAATTTTAGCAGTTTTCATGAAGACAGCACCTCCCTATCAGGCCTGGGTGACAGCACGGAGCCGTCTCTGTCATCCAT
GTATGGCGATGCTGAGGATTCTTCTTCTGACCCTGAGTCACTCACTGAAGCCCCACGAGCTTCTGCCAGGGACGGCTGGTCCCCTCCTCG
TTCCCGTGTGTCTTTGCACAAGGAAGATCCTTCGGAGTCAGAAGAGGAACAGATTGAGATTTGTTCCACACGTGGCTGCCCCAATCCACC
CTCGAGTCCTGCTCATCTTCCCACCCAGGCTGCCATCTGTCCTGCCTCAGCCAAAGTTCTGTCATTAAAATACAGCACTCCGAGAGAGTC
GGTGGCCAGTCCCCGTGAGAAGGCCGCCTGCTTGCCAGGCTCATACACTTCAGGCCCAGACTCTTCCCAGCCATCATCACTCTTGGAGAT
GAGCTCTCAGGAGCATGAAACTCATGCGGACATAAGCACTTCACAGAACCACAGGCCCTCGTGTGCAGAAGAAACCACAGAAGTCACCAG
CGCTAGCTCAGCCATGGAAAACAGTCCGCTGTCTAAAGTAGCCAGGCATTTTCACAGTCCGCCCATCATTCTCAGCTCCCCCAACATGGT
AAATGGCTTGGAACATGACCTGCTAGATGACGAAACCCTGAATCAATACGAAACAAGCATTAATGCAGCTGCCAGTCTGTCCTCCTTCAG
TGTGGATGTCCCTAAGAATGGAGAATCTGTTTTGGAAAACCTCCACATCTCTGAAAGTCAAGACCTGGATGACTTGCTACAGAAACCAAA
AATGATCGCTAGGAGGCCCATCATGGCCTGGTTTAAAGAAATAAATAAACATAACCAAGGCACACATTTGAGGAGCAAAACCGAGAAGGA
ACAACCTCTAATGCCTGCCAGAAGTCCCGACTCCAAGATTCAGATGGTGAGTTCAAGCCAAAAAAAGGGCGTTACTGTGCCTCATAGCCC
TCCTCAGCCGAAAACAAACCTGGAAAATAAGGACCTGTCTAAGAAGAGTCCGGCAGAAATGCTTCTGACTAATGGTCAGAAGGCAAAGTG
TGGTCCGAAGCTGAAGAGGCTCAGCCTCAAGGGCAAGGCCAAAGTCAACTCTGAGGCCCCTGCTGCGAATGCTGTGAAGGCTGGGGGGAC
GGACCACAGGAAACCCTTGATCTCACCCCAGACCTCCCACAAAACACTTTCTAAGGCAGTGTCACAGCGGCTCCATGTAGCCGACCACGA
GGACCCTGACAGAAACACCACAGCTGCCCCCAGGTCCCCCCAGTGTGTGCTGGAAAGCAAGCCACCTCTTGCCACCTCTGGGCCACTGAA
ACCCTCAGTGTCTGACACGAGCATCAGGACATTTGTCTCGCCCCTGACCTCTCCCAAGCCTGTTCCTGAGCAAGGCATGTGGAGCAGGTT
CCACATGGCTGTCCTCTCTGAACCCGACAGAGGTTGCCCAACCACCCCTAAATCTCCTAAGTGTAGAGCAGAGGGCAGGGCGCCCCGTGC
TGACTCCGGGCCGGTGAGTCCGGCAGCGTCTAGGAACGGCATGTCCGTGGCAGGGAACAGACAGAGTGAGCCGCGCCTGGCCAGCCATGT
GGCAGCAGACACAGCCCAACCCAGGCCGACTGGCGAAAAAGGAGGCAACATAATGGCCAGCGATCGCCTCGAAAGAACAAACCAGCTGAA
AATCGTGGAGATTTCTGCTGAAGCAGTGTCAGAGACTGTATGTGGTAACAAGCCAGCTGAAAGCGACAGACGGGGAGGGTGCTTGGCCCA
GGGCAACTGTCAGGAGAAGAGTGAAATCAGGCTCTATCGCCAGGTCGCAGAATCATCCACAAGTCATCCATCCTCACTCCCATCTCATGC
CTCCCAGGCAGAGCAGGAAATGTCACGATCATTCAGCATGGCAAAACTGGCGTCCTCCTCCTCCTCCCTTCAAACAGCCATTAGAAAGGC
AGAATACTCCCAGGGAAAATCAAGCCTGATGTCAGACTCCCGAGGGGTGCCCAGAAACAGCATTCCAGGGGGCCCCTCGGGGGAGGACCA
TCTCTACTTCACCCCAAGGCCAGCGACCAGGACCTACTCCATGCCAGCCCAGTTCTCAAGCCATTTTGGACGGGAGGGTCACCCCCCACA
CAGCCTGGGTCGCTCTCGGGACAGCCAGGTCCCTGTGACAAGCAGTGTTGTCCCCGAGGCAAAGGCATCCAGAGGTGGTCTTCCCAGCCT
GGCTAATGGACAGGGCATATATAGTGTAAAGCCGCTGCTGGACACATCGAGGAATCTTCCAGCCACAGATGAAGGGGATATCATTTCAGT
CCAGGAGACGAGCTGCCTAGTCACAGACAAAATCAAAGTCACCAGACGACACTACTGCTATGAGCAGAACTGGCCCCATGAATCTACCTC
ATTTTTCTCTGTGAAGCAGCGGATCAAGTCTTTTGAGAACCTGGCCAATGCTGACCGGCCTGTAGCCAAGTCCGGGGCTTCCCCATTTTT
GTCGGTGAGCTCCAAGCCTCCCATTGGGAGGCGGTCTTCCGGCAGCATTGTTTCCGGGAGCCTGGGCCACCCAGGTGACGCAGCAGCAAG
GTTGTTGAGACGCAGCTTGAGTTCCTGCAGCGAAAACCAAAGCGAAGCCGGCACCCTCCTGCCCCAGATGGCCAAGTCTCCCTCAATCAT
GACACTGACCATCTCTCGGCAGAACCCACCAGAGACCAGTAGCAAGGGCTCTGATTCGGAACTAAAGAAATCACTTGGTCCTTTGGGAAT
TCCCACCCCAACGATGACCCTGGCTTCTCCTGTTAAGAGGAACAAGTCCTCGGTACGCCACACGCAGCCCTCGCCCGTGTCCCGCTCCAA
GCTCCAGGAGCTGAGAGCCTTGAGCATGCCTGACCTTGACAAGCTCTGCAGCGAGGATTACTCAGCAGGGCCGAGCGCCGTGCTCTTCAA
AACTGAGCTGGAGATCACCCCCAGGAGGTCACCTGGCCCTCCTGCTGGAGGCGTTTCGTGTCCCGAGAAGGGCGGGAACAGGGCCTGTCC
AGGAGGAAGTGGCCCTAAAACCAGTGCTGCTGAGACACCCAGTTCAGCCAGTGATACGGGTGAAGCTGCCCAGGATCTGCCTTTTAGAAG
AAGCTGGTCAGTTAATTTGGATCAACTTCTAGTCTCAGCGGGGGACCAGCAAAGATTACAGTCTGTTTTATCGTCAGTGGGATCGAAATC
TACCATCCTAACTCTCATTCAGGAAGCGAAAGCACAATCAGAGGGTGATCGTGGCATGATGGGACCCCCAGGCGTGCCTGGACCCAAGGG
GTCGATGGGTCATCCTGGAATGCCAGGTGGTATGGGGACCCCTGGAGAGCCTGGACCCCAGGGTCCTCCAGGATCTCGAGGCCCACCAGG
CATGAGGGGAGCAAAGGGACGTCGGGGCCCCCGAGGACCGGACGGACCAGCTGGGGAGCAAGGGTCCAGGGGCCTGAAGGGCCCTCCAGG
ACCCCAGGGCAGACCGGGCCGGCCTGGACAGCAGGGTGTGGCTGGTGAGCGAGGCCACTTGGGCTCGAGAGGCTTTCCTGGCATCCCGGG
TCCCTCAGGCCCCCCAGGCACCAAGGGCCTCCCAGGAGAACCGGGCCCTCAGGGACCCCAGGGGCCAATTGGGCCTCCAGGAGAGATGGG
ACCCAAGGGGCCGCCTGGTGCAGTGGGAGAACCGGGCCTTCCTGGGGAAGCCGGGATGAAGGGTGACCTTGGACCCCTGGGCACTCCTGG
GGAGCAGGGCCTCATTGGGCAACGGGGAGAGCCAGGCCTTGAGGGTGACAGTGGCCCCATGGGACCTGATGGGCTGAAGGGGGACAGGGG
AGACCCAGGGCCTGATGGAGAACATGGCGAGAAAGGCCAGGAAGGGCTGATGGGTGAGGACGGGCCCCCCGGCCCCCCTGGCGTCACTGG
TGTCCGGGGTCCTGAAGGAAAATCAGGGAAGCAAGGCGAGAAGGGCCGCACTGGAGCCAAGGGTGCCAAGGGCTATCAAGGACAGCTGGG
TGAGATGGGCGTCCCTGGAGACCCTGGACCCCCTGGCACTCCAGGCCCTAAAGGGTCCCGGGGCAGCCTGGGACCAACGGGTGCTCCGGG
ACGCATGGGGGCCCAAGGAGAACCGGGACTGGCTGGTTATGATGGACACAAAGGCATTGTGGGACCCCTTGGACCTCCTGGACCAAAAGG
CGAAAAGGGGGAGCAGGGCGAGGACGGCAAGGCTGAGGGGCCCCCTGGGCCACCTGGAGATCGGGGCCCTGTGGGTGATCGAGGAGACCG
CGGGGAACCGGGAGACCCTGGGTACCCTGGACAGGAGGGTGTGCAAGGCCTCCGTGGAAAGCCAGGCCAGCAGGGCCAACCCGGGCATCC
GGGACCCCGGGGGTGGCCGGGACCCAAAGGATCGAAAGGCGCAGAGGGACCAAAGGGAAAGCAAGGCAAGGCAGGGGCCCCAGGCCGGAG
GGGGGTCCAGGGCCTGCAGGGGCTGCCAGGGCCCCGGGGCGTGGTGGGGAGACAGGGCCTCGAGGGCATCGCTGGACCAGATGGGCTTCC
TGGCAGGGACGGGCAAGCAGGACAGCAGGGGGAGCAGGGAGACGATGGGGACCCTGGCCCCATGGGCCCTGCTGGGAAGAGAGGAAATCC
AGGTGTGGCCGGCTTACCTGGAGCACAGGGACCCCCAGGATTCAAGGGTGAGAGTGGGTTACCCGGACAGCTGGGTCCCCCTGGCAAGCG
AGGAACAGAGGGCAGAACGGGGCTCCCTGGAAACCAGGGGGAGCCTGGGTCCAAAGGCCAGCCGGGCGACTCTGGCGAGATGGGCTTCCC
AGGAATGGCAGGTCTCTTCGGACCCAAGGGCCCGCCTGGAGACATTGGCTTCAAAGGCATCCAGGGCCCTCGGGGGCCACCTGGCTTGAT
GGGAAAGGAAGGCATCGTCGGGCCCCTCGGAATCCTGGGACCTTCGGGACTCCCGGGTCCGAAGGGTGACAAAGGCAGCCGTGGGGACTG
GGGATTGCAAGGTCCGAGGGGTCCTCCCGGCCCCAGAGGGCGGCCCGGCCCCCCGGGTCCTCCAGGGGGTCCTATCCAATTGCAACAAGA
TGATCTTGGGGCAGCTTTCCAGACGTGGATGGACACCAGTGGAGCACTCAGGCCAGAGAGTTACAGCTATCCAGACCGGCTGGTGCTGGA
CCAGGGAGGAGAGATCTTTAAAACCTTACACTACCTCAGCAACCTCATCCAGAGCATTAAGACGCCCCTGGGCACCAAAGAGAACCCCGC
CCGGGTCTGCAGGGACCTCATGGACTGTGAGCAGAAGATGGTGGATGGTACCTACTGGGTGGATCCAAACCTTGGCTGCTCCTCTGACAC
CATCGAGGTCTCCTGCAACTTCACTCATGGTGGACAGACGTGTCTCAAGCCCATCACGGCCTCCAAGGTCGAGTTTGCCATCAGCCGGGT
CCAGATGAATTTCCTGCACCTGCTAAGCTCCGAGGTGACCCAGCACATCACCATCCACTGCCTTAACATGACCGTGTGGCAGGAGGGCAC
TGGGCAGACCCCAGCCAAGCAGGCCGTACGCTTCCGGGCCTGGAATGGACAGATTTTTGAAGCTGGGGGTCAGTTCCGGCCCGAGGTGTC
CATGGATGGCTGCAAGGTCCAAGATGGCCGCTGGCATCAGACACTCTTCACCTTCCGGACCCAAGACCCCCAACAGCTGCCCATCATCAG
TGTGGACAACCTCCCTCCTGCCTCATCAGGGAAGCAGTACCGCCTGGAAGTTGGACCTGCGTGCTTCCTCTGACCTCTGACCTCGTGGCC
ACTCTAGGCCTCACGGAGGAGGGAAGAGGAAGAGGCAAGGGGAGGGTACTGAGGGGCAGATGGCTCCAGGAGAGGCAGCTCCCCTGCCCA
AGGGTCCTTGGGCAGACCCCAGCTGTTGTCTGCCCAGTAGAAGTGGGTGGGGGTAGGAGGGGATAGGGTGTCCTTGGGAACAATGGATCC
CAGCTTAGCCCCAAAGACCAACCAAAGAGCCAGCCAGAGTAAGCTGGACCTGCAACCTGCCTGAGCCCCGTGGCCTCTCAGCTCTGCGGC
CACCCCGTTCCCTCCCCAGCTTCCTGCCCAAAGAGCCCCACATTCAAGCCAACTTGAGGGAAGGGGGCGTCTCGTCAGCTGGTCCCTGCT
AGGGAGCTATTGATGTGCAATATTAGAAAGGAGACATGAAAAAAGGAGAAAAGGAAAGACAGAAGTGTATATATATATTATTTAAACAAA
CAAAAAGAAGGTGCGTTACTATTTTTTTTTCACCCGGGAAAGAGGTGAGAGGATGGGAAGGAGCAGCCAGGCGTGGGAAGCGGCGAGATC
CTCGGGCTGGGGGTGCCCACGTTTGCTACCTCCCACTGTGAAATCGCTGGTGCTCACAATTGTCTCTCACAGTGTATGTGATTTTTTTAA
GGAAAAAAAAAAATCCCTATTTAAGATTCTGAAGGTGCTACCATTATTTTGCCACAGACTTTGAAGAAACTTTTGGATGTGGGGCATCAT
CCGCATCTTTCTCTCTCCTCCAAATGACAAAGTTTGGGGAATTTTTGAATTTTCCTAGCATCGCCCTTGTGCTCATCAGGTAATCTGCTA
AGGAGGAAAAAAGAAAAGAAAAAAGGAAAAAAAAAAAAAAAAAGCAAAACAAAAACAAAAACAAAAACCCTACCAGAAACCAGAAGTAGA
GAGATTTACCATATAACTTATGGACTTTGAAATGTCTGTCCTTTTAAGGCAGCAGGGAGGCCTGGGTGCGAAGCATGTTGGCTTGGCCCT
TCACGGTCCTGGAGGGAGGTGAGGCTGGCCTTGGAAGGCGTGCCCTGGAGAGGTCTTGGGTGAAAACTTGACCTTGAAGAAACCAATCAC
AAAAGCGGCGTTGGGTCAGGGCTAGGCTTAGAGGTGAAGCATCAACATGGAACCATCTCAGGAAGCCGCATCGCCTCTTCCGAGGTCCTC
ACTTCCAGGAGCCTGTCCTTGCAAGATGCAATCATCGTTCCTGCTTTTTCATTGTCATTAAATTCTGTAGAAACCCATTGTCATTAGCTC
CAAGTGTAAATTTGGGTCAAGGAGACAGAATAATAATGGGAATCTCGGAGTTCGACACCATAGTGACGTTCAGCGTCCTCTGAATTGTGC
TACATCAGCGAACAAGTCGGCGCTTGAATTGGATTTTGAGGTTATTTTAACCATGGAATTATTTTTATAGAAGGGGAAAATGTATGTGAA
AGTCTCTATTTGTGTATTTCTCTCCTAAAGTTGTGTCTCTTTGGGAATTGGATTTGATTTTTATTATTTAATACCTCACTTTGGCCCGTC
CCCCCTCCCAACACTTCTGTATCCTCGCCCTGCCGCCCCAGCCTGGACGCTCTGCGTGGAAGTGCGTGTTTGTAGCAGCTCGGGCCTCAT
CTCAGCGCTCGGATCCCTCCTGCTGCCAGAATCCACTGGCCTCTGTCTCATTCTTGGGTTTTCCTGCTGTCTTCGTTTACGTCTCTGTCC

>64139_64139_2_PDZD2-COL27A1_PDZD2_chr5_32093130_ENST00000438447_COL27A1_chr9_117014873_ENST00000356083_length(amino acids)=3469AA_BP=2758
MGVSTMPITQDNAVLHLPLLYQWLQNSLQEGGDGPEQRLCQAAIQKLQEYIQLNFAVDESTVPPDHSPPEMEICTVYLTKELGDTETVGL
SFGNIPVFGDYGEKRRGGKKRKTHQGPVLDVGCIWVTELRKNSPAGKSGKVRLRDEILSLNGQLMVGVDVSGASYLAEQCWNGGFIYLIM
LRRFKHKAHSTYNGNSSNSSEPGETPTLELGDRTAKKGKRTRKFGVISRPPANKAPEESKGSAGCEVSSDPSTELENGPDPELGNGHVFQ
LENGPDSLKEVAGPHLERSEVDRGTEHRIPKTDAPLTTSNDKRRFSKGGKTDFQSSDCLAREEVGRIWKMELLKESDGLGIQVSGGRGSK
RSPHAIVVTQVKEGGAAHRDGRLSLGDELLVINGHLLVGLSHEEAVAILRSATGMVQLVVASKENSAEDLLRLTSKSLPDLTSSVEDVSS
WTDNEDQEADGEEDEGTSSSVQRAMPGTDEPQDVCGAEESKGNLESPKQGSNKIKLKSRLSGGVHRLESVEEYNELMVRNGDPRIRMLEV
SRDGRKHSLPQLLDSSSASQEYHIVKKSTRSLSTTQVESPWRLIRPSVISIIGLYKEKGKGLGFSIAGGRDCIRGQMGIFVKTIFPNGSA
AEDGRLKEGDEILDVNGIPIKGLTFQEAIHTFKQIRSGLFVLTVRTKLVSPSLTPCSTPTHMSRSASPNFNTSGGASAGGSDEGSSSSLG
RKTPGPKDRIVMEVTLNKEPRVGLGIGACCLALENSPPGIYIHSLAPGSVAKMESNLSRGDQILEVNSVNVRHAALSKVHAILSKCPPGP
VRLVIGRHPNPKVSEQEMDEVIARSTYQESKEANSSPGLGTPLKSPSLAKKDSLISESELSQYFAHDVPGPLSDFMVAGSEDEDHPGSGC
STSEEGSLPPSTSTHKEPGKPRANSLVTLGSHRASGLFHKQVTVARQASLPGSPQALRNPLLRQRKVGCYDANDASDEEEFDREGDCISL
PGALPGPIRPLSEDDPRRVSISSSKGMDVHNQEERPRKTLVSKAISAPLLGSSVDLEESIPEGMVDAASYAANLTDSAEAPKGSPGSWWK
KELSGSSSAPKLEYTVRTDTQSPTNTGSPSSPQQKSEGLGSRHRPVARVSPHCKRSEAEAKPSGSQTVNLTGRANDPCDLDSRVQATSVK
VTVAGFQPGGAVEKESLGKLTTGDACVSTSCELASALSHLDASHLTENLPKAASELGQQPMTELDSSSDLISSPGKKGAAHPDPSKTSVD
TGQVSRPENPSQPASPRVTKCKARSPVRLPHEGSPSPGEKAAAPPDYSKTRSASETSTPHNTRRVAALRGAGPGAEGMTPAGAVLPGDPL
TSQEQRQGAPGNHSKALEMTGIHAPESSQEPSLLEGADSVSSRAPQASLSMLPSTDNTKEACGHVSGHCCPGGSRESPVTDIDSFIKELD
ASAARSPSSQTGDSGSQEGSAQGHPPAGAGGGSSCRAEPVPGGQTSSPRRAWAAGAPAYPQWASQPSVLDSINPDKHFTVNKNFLSNYSR
NFSSFHEDSTSLSGLGDSTEPSLSSMYGDAEDSSSDPESLTEAPRASARDGWSPPRSRVSLHKEDPSESEEEQIEICSTRGCPNPPSSPA
HLPTQAAICPASAKVLSLKYSTPRESVASPREKAACLPGSYTSGPDSSQPSSLLEMSSQEHETHADISTSQNHRPSCAEETTEVTSASSA
MENSPLSKVARHFHSPPIILSSPNMVNGLEHDLLDDETLNQYETSINAAASLSSFSVDVPKNGESVLENLHISESQDLDDLLQKPKMIAR
RPIMAWFKEINKHNQGTHLRSKTEKEQPLMPARSPDSKIQMVSSSQKKGVTVPHSPPQPKTNLENKDLSKKSPAEMLLTNGQKAKCGPKL
KRLSLKGKAKVNSEAPAANAVKAGGTDHRKPLISPQTSHKTLSKAVSQRLHVADHEDPDRNTTAAPRSPQCVLESKPPLATSGPLKPSVS
DTSIRTFVSPLTSPKPVPEQGMWSRFHMAVLSEPDRGCPTTPKSPKCRAEGRAPRADSGPVSPAASRNGMSVAGNRQSEPRLASHVAADT
AQPRPTGEKGGNIMASDRLERTNQLKIVEISAEAVSETVCGNKPAESDRRGGCLAQGNCQEKSEIRLYRQVAESSTSHPSSLPSHASQAE
QEMSRSFSMAKLASSSSSLQTAIRKAEYSQGKSSLMSDSRGVPRNSIPGGPSGEDHLYFTPRPATRTYSMPAQFSSHFGREGHPPHSLGR
SRDSQVPVTSSVVPEAKASRGGLPSLANGQGIYSVKPLLDTSRNLPATDEGDIISVQETSCLVTDKIKVTRRHYCYEQNWPHESTSFFSV
KQRIKSFENLANADRPVAKSGASPFLSVSSKPPIGRRSSGSIVSGSLGHPGDAAARLLRRSLSSCSENQSEAGTLLPQMAKSPSIMTLTI
SRQNPPETSSKGSDSELKKSLGPLGIPTPTMTLASPVKRNKSSVRHTQPSPVSRSKLQELRALSMPDLDKLCSEDYSAGPSAVLFKTELE
ITPRRSPGPPAGGVSCPEKGGNRACPGGSGPKTSAAETPSSASDTGEAAQDLPFRRSWSVNLDQLLVSAGDQQRLQSVLSSVGSKSTILT
LIQEAKAQSEGDRGMMGPPGVPGPKGSMGHPGMPGGMGTPGEPGPQGPPGSRGPPGMRGAKGRRGPRGPDGPAGEQGSRGLKGPPGPQGR
PGRPGQQGVAGERGHLGSRGFPGIPGPSGPPGTKGLPGEPGPQGPQGPIGPPGEMGPKGPPGAVGEPGLPGEAGMKGDLGPLGTPGEQGL
IGQRGEPGLEGDSGPMGPDGLKGDRGDPGPDGEHGEKGQEGLMGEDGPPGPPGVTGVRGPEGKSGKQGEKGRTGAKGAKGYQGQLGEMGV
PGDPGPPGTPGPKGSRGSLGPTGAPGRMGAQGEPGLAGYDGHKGIVGPLGPPGPKGEKGEQGEDGKAEGPPGPPGDRGPVGDRGDRGEPG
DPGYPGQEGVQGLRGKPGQQGQPGHPGPRGWPGPKGSKGAEGPKGKQGKAGAPGRRGVQGLQGLPGPRGVVGRQGLEGIAGPDGLPGRDG
QAGQQGEQGDDGDPGPMGPAGKRGNPGVAGLPGAQGPPGFKGESGLPGQLGPPGKRGTEGRTGLPGNQGEPGSKGQPGDSGEMGFPGMAG
LFGPKGPPGDIGFKGIQGPRGPPGLMGKEGIVGPLGILGPSGLPGPKGDKGSRGDWGLQGPRGPPGPRGRPGPPGPPGGPIQLQQDDLGA
AFQTWMDTSGALRPESYSYPDRLVLDQGGEIFKTLHYLSNLIQSIKTPLGTKENPARVCRDLMDCEQKMVDGTYWVDPNLGCSSDTIEVS
CNFTHGGQTCLKPITASKVEFAISRVQMNFLHLLSSEVTQHITIHCLNMTVWQEGTGQTPAKQAVRFRAWNGQIFEAGGQFRPEVSMDGC

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Fusion Gene PPI Analysis for PDZD2-COL27A1


check button Go to ChiPPI (Chimeric Protein-Protein interactions) to see the chimeric PPI interaction in

ChiPPI page.


check button Protein-protein interactors with each fusion partner protein in wild-type (BIOGRID-3.4.160)
HgeneHgene's interactorsTgeneTgene's interactors


check button - Retained PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenStill interaction with


check button - Lost PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


check button - Retained PPIs, but lost function due to frame-shift fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


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Related Drugs for PDZD2-COL27A1


check button Drugs targeting genes involved in this fusion gene.
(DrugBank Version 5.1.8 2021-05-08)
PartnerGeneUniProtAccDrugBank IDDrug nameDrug activityDrug typeDrug status

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Related Diseases for PDZD2-COL27A1


check button Diseases associated with fusion partners.
(DisGeNet 4.0)
PartnerGeneDisease IDDisease name# pubmedsSource