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Center for Computational Systems Medicine
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Fusion Gene Summary

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Fusion Gene ORF analysis

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Fusion Genomic Features

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Fusion Protein Features

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Fusion Gene Sequence

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Fusion Gene PPI analysis

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Related Drugs

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Related Diseases

Fusion gene:PEBP4-UNC5D (FusionGDB2 ID:64229)

Fusion Gene Summary for PEBP4-UNC5D

check button Fusion gene summary
Fusion gene informationFusion gene name: PEBP4-UNC5D
Fusion gene ID: 64229
HgeneTgene
Gene symbol

PEBP4

UNC5D

Gene ID

157310

137970

Gene namephosphatidylethanolamine binding protein 4unc-5 netrin receptor D
SynonymsCORK-1|CORK1|GWTM1933|HEL-S-300|PEBP-4|PRO4408|hPEBP4PRO34692|Unc5h4
Cytomap

8p21.3

8p12

Type of geneprotein-codingprotein-coding
Descriptionphosphatidylethanolamine-binding protein 4cousin-of-RKIP 1 proteinepididymis secretory protein Li 300epididymis secretory sperm binding proteinprotein cousin-of-RKIP 1netrin receptor UNC5Dnetrin receptor Unc5h4protein unc-5 homolog 4protein unc-5 homolog Dunc-5 homolog 4unc-5 homolog D
Modification date2020031320200313
UniProtAcc..
Ensembl transtripts involved in fusion geneENST00000256404, ENST00000521284, 
ENST00000449677, ENST00000287272, 
ENST00000404895, ENST00000416672, 
ENST00000420357, ENST00000453357, 
Fusion gene scores* DoF score4 X 4 X 2=3217 X 13 X 6=1326
# samples 420
** MAII scorelog2(4/32*10)=0.321928094887362
effective Gene in Pan-Cancer Fusion Genes (eGinPCFGs).
DoF>8 and MAII>0		log2(20/1326*10)=-2.72900887033786
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0
Context

PubMed: PEBP4 [Title/Abstract] AND UNC5D [Title/Abstract] AND fusion [Title/Abstract]

Most frequent breakpointPEBP4(22582356)-UNC5D(35406810), # samples:3
Anticipated loss of major functional domain due to fusion event.
* DoF score (Degree of Frequency) = # partners X # break points X # cancer types
** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10)

check button Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez
PartnerGeneGO IDGO termPubMed ID
TgeneUNC5D

GO:0098742

cell-cell adhesion via plasma-membrane adhesion molecules

26235030


check buttonFusion gene breakpoints across PEBP4 (5'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.
all structure

check buttonFusion gene breakpoints across UNC5D (3'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.
all structure

check button Fusion gene information from two resources (ChiTars 5.0 and ChimerDB 4.0)
* All genome coordinats were lifted-over on hg19.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
SourceDiseaseSampleHgeneHchrHbpHstrandTgeneTchrTbpTstrand
ChimerDB4BRCATCGA-A2-A1FV-01APEBP4chr8

22582356

-UNC5Dchr8

35406810

+


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Fusion Gene ORF analysis for PEBP4-UNC5D

check button Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
ORFHenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrand
5CDS-intronENST00000256404ENST00000449677PEBP4chr8

22582356

-UNC5Dchr8

35406810

+
In-frameENST00000256404ENST00000287272PEBP4chr8

22582356

-UNC5Dchr8

35406810

+
In-frameENST00000256404ENST00000404895PEBP4chr8

22582356

-UNC5Dchr8

35406810

+
In-frameENST00000256404ENST00000416672PEBP4chr8

22582356

-UNC5Dchr8

35406810

+
In-frameENST00000256404ENST00000420357PEBP4chr8

22582356

-UNC5Dchr8

35406810

+
In-frameENST00000256404ENST00000453357PEBP4chr8

22582356

-UNC5Dchr8

35406810

+
intron-3CDSENST00000521284ENST00000287272PEBP4chr8

22582356

-UNC5Dchr8

35406810

+
intron-3CDSENST00000521284ENST00000404895PEBP4chr8

22582356

-UNC5Dchr8

35406810

+
intron-3CDSENST00000521284ENST00000416672PEBP4chr8

22582356

-UNC5Dchr8

35406810

+
intron-3CDSENST00000521284ENST00000420357PEBP4chr8

22582356

-UNC5Dchr8

35406810

+
intron-3CDSENST00000521284ENST00000453357PEBP4chr8

22582356

-UNC5Dchr8

35406810

+
intron-intronENST00000521284ENST00000449677PEBP4chr8

22582356

-UNC5Dchr8

35406810

+

check buttonORFfinder result based on the fusion transcript sequence of in-frame fusion genes.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandSeq length
(transcript)		BP loci
(transcript)		Predicted start
(transcript)		Predicted stop
(transcript)		Seq length
(amino acids)
ENST00000256404PEBP4chr822582356-ENST00000287272UNC5Dchr835406810+91486099231601022
ENST00000256404PEBP4chr822582356-ENST00000453357UNC5Dchr835406810+74676099233671091
ENST00000256404PEBP4chr822582356-ENST00000404895UNC5Dchr835406810+34306099233671091
ENST00000256404PEBP4chr822582356-ENST00000420357UNC5Dchr835406810+34526099231661024
ENST00000256404PEBP4chr822582356-ENST00000416672UNC5Dchr835406810+40286099233821096

check buttonDeepORF prediction of the coding potential based on the fusion transcript sequence of in-frame fusion genes. DeepORF is a coding potential classifier based on convolutional neural network by comparing the real Ribo-seq data. If the no-coding score < 0.5 and coding score > 0.5, then the in-frame fusion transcript is predicted as being likely translated.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandNo-coding scoreCoding score
ENST00000256404ENST00000287272PEBP4chr822582356-UNC5Dchr835406810+7.13E-050.9999287
ENST00000256404ENST00000453357PEBP4chr822582356-UNC5Dchr835406810+0.0001742710.9998258
ENST00000256404ENST00000404895PEBP4chr822582356-UNC5Dchr835406810+0.0006715090.9993285
ENST00000256404ENST00000420357PEBP4chr822582356-UNC5Dchr835406810+0.0007092740.9992907
ENST00000256404ENST00000416672PEBP4chr822582356-UNC5Dchr835406810+0.0004068680.9995932

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Fusion Genomic Features for PEBP4-UNC5D


check buttonFusionAI prediction of the potential fusion gene breakpoint based on the pre-mature RNA sequence context (+/- 5kb of individual partner genes, total 20kb length sequence). FusionAI is a fusion gene breakpoint classifier based on convolutional neural network by comparing the fusion positive and negative sequence context of ~ 20K fusion gene data. From here, we can have the relative potentency of the 20K genomic sequence how individual sequnce will be likely used as the gene fusion breakpoints.
HgeneHchrHbpHstrandTgeneTchrTbpTstrand1-pp (fusion gene breakpoint)
PEBP4chr822582355-UNC5Dchr835406809+0.0091258440.9908742
PEBP4chr822582355-UNC5Dchr835406809+0.0091258440.9908742

check buttonDistribution of 44 human genomic features loci across 20kb length fusion breakpoint regions. We integrated a total of 44 different types of human genomic feature loci information across five big categories including virus integration sites, repeats, structural variants, chromatin states, and gene expression regulation. More details are in help page.
genomic feature

check buttonDistribution of 44 human genomic features loci across 20kb length fusion breakpoint regions that are ovelapped with the top 1% feature importance score regions. More details are in help page.
genomic feature of top 1%

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Fusion Protein Features for PEBP4-UNC5D


check button Four levels of functional features of fusion genes
Go to FGviewer search page for the most frequent breakpoint (https://ccsmweb.uth.edu/FGviewer/chr8:22582356/chr8:35406810)
- FGviewer provides the online visualization of the retention search of the protein functional features across DNA, RNA, protein, and pathological levels.
- How to search
1. Put your fusion gene symbol.
2. Press the tab key until there will be shown the breakpoint information filled.
4. Go down and press 'Search' tab twice.
4. Go down to have the hyperlink of the search result.
5. Click the hyperlink.
6. See the FGviewer result for your fusion gene.
FGviewer

check buttonMain function of each fusion partner protein. (from UniProt)
HgeneTgene
..
FUNCTION: Transcriptional activator which is required for calcium-dependent dendritic growth and branching in cortical neurons. Recruits CREB-binding protein (CREBBP) to nuclear bodies. Component of the CREST-BRG1 complex, a multiprotein complex that regulates promoter activation by orchestrating a calcium-dependent release of a repressor complex and a recruitment of an activator complex. In resting neurons, transcription of the c-FOS promoter is inhibited by BRG1-dependent recruitment of a phospho-RB1-HDAC1 repressor complex. Upon calcium influx, RB1 is dephosphorylated by calcineurin, which leads to release of the repressor complex. At the same time, there is increased recruitment of CREBBP to the promoter by a CREST-dependent mechanism, which leads to transcriptional activation. The CREST-BRG1 complex also binds to the NR2B promoter, and activity-dependent induction of NR2B expression involves a release of HDAC1 and recruitment of CREBBP (By similarity). {ECO:0000250}.FUNCTION: Transcriptional activator which is required for calcium-dependent dendritic growth and branching in cortical neurons. Recruits CREB-binding protein (CREBBP) to nuclear bodies. Component of the CREST-BRG1 complex, a multiprotein complex that regulates promoter activation by orchestrating a calcium-dependent release of a repressor complex and a recruitment of an activator complex. In resting neurons, transcription of the c-FOS promoter is inhibited by BRG1-dependent recruitment of a phospho-RB1-HDAC1 repressor complex. Upon calcium influx, RB1 is dephosphorylated by calcineurin, which leads to release of the repressor complex. At the same time, there is increased recruitment of CREBBP to the promoter by a CREST-dependent mechanism, which leads to transcriptional activation. The CREST-BRG1 complex also binds to the NR2B promoter, and activity-dependent induction of NR2B expression involves a release of HDAC1 and recruitment of CREBBP (By similarity). {ECO:0000250}.

check buttonRetention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at

download page


* Minus value of BPloci means that the break pointn is located before the CDS.
- In-frame and retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
TgeneUNC5Dchr8:22582356chr8:35406810ENST00000404895017153_24434954.0DomainNote=Ig-like C2-type
TgeneUNC5Dchr8:22582356chr8:35406810ENST00000404895017252_30634954.0DomainTSP type-1 1
TgeneUNC5Dchr8:22582356chr8:35406810ENST00000404895017308_36034954.0DomainTSP type-1 2
TgeneUNC5Dchr8:22582356chr8:35406810ENST00000404895017542_68234954.0DomainZU5
TgeneUNC5Dchr8:22582356chr8:35406810ENST0000040489501754_15134954.0DomainNote=Ig-like
TgeneUNC5Dchr8:22582356chr8:35406810ENST00000404895017859_93634954.0DomainNote=Death
TgeneUNC5Dchr8:22582356chr8:35406810ENST00000453357017153_24429949.0DomainNote=Ig-like C2-type
TgeneUNC5Dchr8:22582356chr8:35406810ENST00000453357017252_30629949.0DomainTSP type-1 1
TgeneUNC5Dchr8:22582356chr8:35406810ENST00000453357017308_36029949.0DomainTSP type-1 2
TgeneUNC5Dchr8:22582356chr8:35406810ENST00000453357017542_68229949.0DomainZU5
TgeneUNC5Dchr8:22582356chr8:35406810ENST0000045335701754_15129949.0DomainNote=Ig-like
TgeneUNC5Dchr8:22582356chr8:35406810ENST00000453357017859_93629949.0DomainNote=Death
TgeneUNC5Dchr8:22582356chr8:35406810ENST0000040489501733_37934954.0Topological domainExtracellular
TgeneUNC5Dchr8:22582356chr8:35406810ENST00000404895017401_95334954.0Topological domainCytoplasmic
TgeneUNC5Dchr8:22582356chr8:35406810ENST0000045335701733_37929949.0Topological domainExtracellular
TgeneUNC5Dchr8:22582356chr8:35406810ENST00000453357017401_95329949.0Topological domainCytoplasmic
TgeneUNC5Dchr8:22582356chr8:35406810ENST00000404895017380_40034954.0TransmembraneHelical
TgeneUNC5Dchr8:22582356chr8:35406810ENST00000453357017380_40029949.0TransmembraneHelical

- In-frame and not-retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note


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Fusion Gene Sequence for PEBP4-UNC5D


check button For in-frame fusion transcripts, we provide the fusion transcript sequences and fusion amino acid sequences. To have fusion amino acid sequence, we ran ORFfinder and chose the longest ORF among the all predicted ones.
>64229_64229_1_PEBP4-UNC5D_PEBP4_chr8_22582356_ENST00000256404_UNC5D_chr8_35406810_ENST00000287272_length(transcript)=9148nt_BP=609nt
CCCAAAGTACTTGTGTCCGGGTGGTGGACTGGATTAGCTGCGGAGCCCTGGAAGCTGCCTGTCCTTCTCCCTGTGCTTAACCAGAGGTGC
CCATGGGTTGGACAATGAGGCTGGTCACAGCAGCACTGTTACTGGGTCTCATGATGGTGGTCACTGGAGACGAGGATGAGAACAGCCCGT
GTGCCCATGAGGCCCTCTTGGACGAGGACACCCTCTTTTGCCAGGGCCTTGAAGTTTTCTACCCAGAGTTGGGGAACATTGGCTGCAAGG
TTGTTCCTGATTGTAACAACTACAGACAGAAGATCACCTCCTGGATGGAGCCGATAGTCAAGTTCCCGGGGGCCGTGGACGGCGCAACCT
ATATCCTGGTGATGGTGGATCCAGATGCCCCTAGCAGAGCAGAACCCAGACAGAGATTCTGGAGACATTGGCTGGTAACAGATATCAAGG
GCGCCGACCTGAAGAAAGGGAAGATTCAGGGCCAGGAGTTATCAGCCTACCAGGCTCCCTCCCCACCGGCACACAGTGGCTTCCATCGCT
ACCAGTTCTTTGTCTATCTTCAGGAAGGAAAAGTCATCTCTCTCCTTCCCAAGGAAAACAAAACTCGAGGAACTGACAATGGCGAAGCCC
TTCCCGAATCCATCCCATCAGCTCCTGGGACACTGCCTCATTTCATAGAGGAGCCAGATGATGCTTATATTATCAAGAGCAACCCTATTG
CACTCAGGTGCAAAGCGAGGCCAGCCATGCAGATATTCTTCAAATGCAACGGCGAGTGGGTCCATCAGAACGAGCACGTCTCTGAAGAGA
CTCTGGACGAGAGCTCAGGTTTGAAGGTCCGCGAAGTGTTCATCAATGTTACTAGGCAACAGGTGGAGGACTTCCATGGGCCCGAGGACT
ATTGGTGCCAGTGTGTGGCGTGGAGCCACCTGGGTACCTCCAAGAGCAGGAAGGCCTCTGTGCGCATAGCCTATTTACGGAAAAACTTTG
AACAAGACCCACAAGGAAGGGAAGTTCCCATTGAAGGCATGATTGTACTGCACTGCCGCCCACCAGAGGGAGTCCCTGCTGCCGAGGTGG
AATGGCTGAAAAATGAAGAGCCCATTGACTCTGAACAAGACGAGAACATTGACACCAGGGCTGACCATAACCTGATCATCAGGCAGGCAC
GGCTCTCGGACTCAGGAAATTACACCTGCATGGCAGCCAACATCGTGGCTAAGAGGAGAAGCCTGTCGGCCACTGTTGTGGTCTACGTGG
ATGGGAGCTGGGAAGTGTGGAGCGAATGGTCCGTCTGCAGTCCAGAGTGTGAACATTTGCGGATCCGGGAGTGCACAGCACCACCCCCGA
GAAATGGGGGCAAATTCTGTGAAGGTCTAAGCCAGGAATCTGAAAACTGCACAGATGGTCTTTGCATCCTAGATAAAAAACCTCTTCATG
AAATAAAACCCCAAAGCATTGAGAATGCCAGCGACATTGCTTTGTACTCGGGCTTGGGTGCTGCCGTCGTGGCCGTTGCAGTCCTGGTCA
TTGGTGTCACCCTTTACAGACGGAGCCAGAGTGACTATGGCGTGGACGTCATTGACTCTTCTGCATTGACAGGTAACTCCCTGCTCCTGA
ATTCTGCCATGCAGCCAGATCTGACAGTGAGCCGGACATACAGCGGACCCATCTGTCTGCAGGACCCTCTGGACAAGGAGCTCATGACAG
AGTCCTCACTCTTTAACCCTTTGTCGGACATCAAAGTGAAAGTCCAGAGCTCGTTCATGGTTTCCCTGGGAGTGTCTGAGAGAGCTGAGT
ACCACGGCAAGAATCATTCCAGGACTTTTCCCCATGGAAACAACCACAGCTTTAGTACAATGCATCCCAGAAATAAAATGCCCTACATCC
AAAATCTGTCATCACTCCCCACAAGGACAGAACTGAGGACAACTGGTGTCTTTGGCCATTTAGGGGGGCGCTTAGTAATGCCAAATACAG
GGGTGAGCTTACTCATACCACACGGTGCCATCCCAGAGGAGAATTCTTGGGAGATTTATATGTCCATCAACCAAGGTGAACCCAGCCTCC
AGTCAGATGGCTCTGAGGTGCTCCTGAGTCCTGAAGTCACCTGTGGTCCTCCAGACATGATCGTCACCACTCCCTTTGCATTGACCATCC
CGCACTGTGCAGATGTCAGTTCTGAGCATTGGAATATCCATTTAAAGAAGAGGACACAGCAGGGCAAATGGGAGGAAGTGATGTCAGTGG
AAGATGAATCTACATCCTGTTACTGCCTTTTGGACCCCTTTGCGTGTCATGTGCTCCTGGACAGCTTTGGGACCTATGCGCTCACTGGAG
AGCCAATCACAGACTGTGCCGTGAAGCAACTGAAGGTGGCGGTTTTTGGCTGCATGTCCTGTAACTCCCTGGATTACAACTTGAGAGTTT
ACTGTGTGGACAATACCCCTTGTGCATTTCAGGAAGTGGTTTCAGATGAAAGGCATCAAGGTGGACAGCTCCTGGAAGAACCAAAATTGC
TGCATTTCAAAGGGAATACCTTTAGTCTTCAGATTTCTGTCCTTGATATTCCCCCATTCCTCTGGAGAATTAAACCATTCACTGCCTGCC
AGGAAGTCCCGTTCTCCCGCGTGTGGTGCAGTAACCGGCAGCCCCTGCACTGTGCCTTCTCCCTGGAGCGTTATACGCCCACTACCACCC
AGCTGTCCTGCAAAATCTGCATTCGGCAGCTCAAAGGCCATGAACAGATCCTCCAAGTGCAGACATCAATCCTAGAGAGTGAACGAGAAA
CCATCACTTTCTTCGCACAAGAGGACAGCACTTTCCCTGCACAGACTGGCCCCAAAGCCTTCAAAATTCCCTACTCCATCAGACAGCGGA
TTTGTGCTACATTTGATACCCCCAATGCCAAAGGCAAGGACTGGCAGATGTTAGCACAGAAAAACAGCATCAACAGGAATTTATCTTATT
TCGCTACACAAAGTAGCCCATCTGCTGTCATTTTGAACCTGTGGGAAGCTCGTCATCAGCATGATGGTGATCTTGACTCCCTGGCCTGTG
CCCTTGAAGAGATTGGGAGGACACACACGAAACTCTCAAACATTTCAGAATCCCAGCTTGATGAAGCCGACTTCAACTACAGCAGGCAAA
ATGGACTCTAGTCCACTTCCTCCCATGAGACAGAGTGATGGCCAGCTTGGGGACATTTGCTTTAAATGGGAAAGAGGCCGCTTTCTGCCC
AGTGGCGTTGGGGGAATTCAGCCTTCATTTATAATCAGTGAGATTCCCCTGTTGAAGAAACTAAATTTTATATAGGTAAAACATGTTAAT
AGGGAAGAGTACAAGCTCTCTTACATATAAGAGGGCTCTACTATCTCCTTGGAATCCACATTTGGGTTAACTCCTCAGATTTGGAGTGGC
AAGGATAAAAGTGAGGGCAGAAGTAGCTGTGGGAAAAGATGAGCTATGATAATGCTGGGAAGGCAGAGATTGATTAAGTGCATGCTTTGA
AATAGGTTTTTAATGATGTGCCCCAAAGGGCCAGCTGATTCTGGTACTAGATTGTCAGAGTTTTCTACCAACTGGCATCTGTGATGTCAG
AGATCATTGTAAAAATGGCTTTTAGACGTGAAACAGGGTTGCCAACCCATTTGTATGACTTCAACAACGTCAAGGAGGGCATTTAGAATT
TAGAATCTGAGCACATCACACCAGCACCAGCTCCCTGTCTCTTCTAGCCACTTAATGGAGACACAATGGAGAGGTAAGACAGACCACAAA
CTAGTTCTTATAGTGTACTCCACCTTTTACTTTTTTCCTGAGACAAATCTACCCTTATTCTTTCTTCCTCTTCCTTACCCCTTGCAGTAG
GGAGGTATCAAGGAGCATAATTAAACTTGTCAATACGGAAAGTTGTTTTTTCTAACACAACAAAGTGGGACCATCTCTATTCCCATCTAA
GCCACTCAAATTGCTGAGTGCTATTAGAACACAGCTTATTACATGGATATGGGGACAGGAGAGATTAAAGCAGGTTCAAAAACACATGAA
CTGCAGATGCCATAGGCCTCAAATCAGCTGTAATTCTAGGAGACACGTGTTGATCTAGTTATCTAACATTGTTGTTATAAGAAAATGAGT
TTACTGCATTTTTCAATCCAGATTCTTGAAATTGTCTAACATGTGGGTACTGTGTCATCACAAAATCTCTCAGTAAGGCTATATGTGATC
CTCATTTTGCCTCTTGGGAAATTAGCAGATAGTCTTTGCTCTAAATGATATCTGAGTAAATAGACTTGAGGAATCCTCTACCACAGTGTC
CCTGAAACCACATGCATCATTCAGGAAGCCTTCACCCTGTGACTATTCAGCCTCCCTGAATATGCTTTCTCTATAGAACCACTAACATAT
GGCTATTGCTCTATGATTTTTTTTTTTACATTAGGAGGCAGTGATATTGTGGAAGATTGAAATCCACAGATAATTCATGACCCTCATCTT
ATCACTTTACTCCATCTTTTTATCCTATTAAATTATTTTTGACAAGATGTCCTGGTAGACTAAAGGTGAACAGATTTGCTCTTGCTCATC
TTCTGGTGGATATTTTAACTTGCTATTCACAATCAGGACAACCAAAGTCAAGGACCCAGATGAACCACAAGGCAGCTAGTCAGCTACTTA
GAGGTTGGTTACATTCGAATAAAAAGTAGTCAGGGAATGGGGGAGGTGGGGAGTTGGGGAGTACTTGGCAGTTGGGATATGATCCATTTT
TTTAAACAAGTTTTTTGTAGATCCCTTGTAAAATAATAATAATAATGTTGTGAATCTCCATGCCAAGTGAAAAAGGCCTAAAGATGAGTT
GAATTTGTGATACCATGGGTAAGGCATGGAAGAACTCTTGAATGTGTTGGCCATTTTCTCTAACTAACATGTGGTATGTATGGTCCCCTA
TATTAGATAGAAGTCTTTGCTACATGTAATTCAAAAGCATCTCGCTTTTCTCAGGAACCAAAGGCTTATGATGTAGGACAAAGAAATCAT
CTTAGAACTGTCAAGCATATTTTCACAATACCATGTCAAGATCAGGAAAACACCCTTTTGCTAGTGTGCTTAACTTATTTATTTCTTCTA
GGAAACAATAGATAAACAGCATGAAAATGTAAATCATCTGGCATCACTGATAGAATTTCTGAAAGAGAAAGAGAAGTAGATGGTCAACCA
GTCACTAGTTGGTTGGCATGAGGTGGTGTGCAGAGGAAAGCTGCATTCACTATTGAGTAAAAACTTGTAGAAAGCACATTATAGAGCTTA
TGTTGGAATCCATCTTGGAGGATTTTTGTTTTAAACTGTCTTTAGCATTTTCCCTCTTCCCTTCTAATGGGCATTATAATTGTTTCATCT
ACTCTGTGAATCTACATAGGTCTTTTTTTTTAGATGTTTGATACATTTTAAGTATTTTTAAATAGATGAAAATTCTAAATGATTTTCCCT
CAAATCTATCTAGATTATTTTAAGATGAGACAAGATTATTGTCAATCCCTGAATGTCTGGAGTTACCTCCCATGGATTTTTTTTTCCTTT
GGCCTGGGTTTTATAAACAACTTGAACATCATATCATATAGGATAACAAAGGAGGAAGTTAACTTAATTCACCTCAGACTTCAGCCTAAG
ATTCAATCAAATTCATCCTTCAGCCTGTCTTGTTTCTTCTTTATGTTTCTTTTACTTATTGCTGCTAGGATCCTACATAGGATTTCTATA
GAAATGTATGAAATTCTGTGGTCACTGCATGTCAGGATTGCACAGTATGTTACAATACAATTTCAAAGAGAACCCACATTTGTGAGATTT
ACAGACCAAGGTGTGGTGGAGGAGGTAGAATTGCAGATCAGATAAAAAGTGAGCTTACACTTGAACTTAGTTATTCACTGTGACCTAAAT
TTAGTCCTATTGTAATATGTGCCTGTCACAACACAAATACCCCTCTTGAAAGAGATTTACTCATCTATCCAAGCACTTAATTTGGAAATT
TTATTGTCCTATTGCAAAATGAAACAAAATTAAAAGTGGCCTCGAGTACTTGGTAAGTTACTTAAAATTTTTACAAAAATATCCCACTCA
ATGCCAAATCTTTCAGTCCTCAAAGGCATTTAAGTCCAATAGTCATGCTTTAAATATGGCTTTAAATTATGCCACCAAAATGGTGCACTT
CACAGATTCACCAGACTGTAGCATCATAAAGTTAATTTACAGTTTTTACAACATTGCTTCTACATTCTTACTGGTTTACATTAAAATCCT
TTAAGCCAAAAGGAAGCTTGCTCTATGGATTTAAATGCAAACTTCATTTACCAGTGCAGGAAGTCTCATAAAACTCAGATGTACTCCCAC
AAAAATTTTATTGGCCTTTTTGTAAGAGATGAAAAAGAATTGACACAGTTCTCTTTAAAGAGAAGAACTTTTTTATTATTATTTTTATCT
CCAACTGCAGGTGGTGTCTTTTGCCAAGGTCTCTGTATTTTTCTTTCAGTTGTCTTTGGGAGGGGATGTTAAGTCAAATCACTAAAACAG
GGTTCTCTTTGGATTAAAAGTTCTGGATTTATTGCAACTATTTTCCTTGAGAAACATTCTCAGCATCAGGATTGATAAACAAATGTAGAT
GATTAAAATAGGATAATTGGTTTTAGATAATATCTTCTACTGCCAAACTTCTGGCAAATTTACCTGTGAATTTCAAAATGTTATAAAATC
TCTTGATATGCTTTTGTTTTTCCTTTTAGCCATTTTCTCTTCAATTTCTTAGTCCCTCTGCCCTCTGTAAATGTGTTGAGTGATATAGCT
ATCAGATGTATTGAAGGCAAAGTTCTCGCAGAGGTCTCTGTTCCAGCTCTGTAAAGGTCACAGGAATCGTGAAGGAGCTGAGAAATCTTC
CTCTCCGGCCCACTGTCTGTGGCCCATTGTCATTGTTTCCTCATGAAACATTGCAGAGTTTGAATCCTCAGTAACTCTCATTGACTGGAT
TAGAGGTGATGGCCACAGCAAATGGGAGAGCAAAATGTTGGCCTACAGAGAATGACACAATTTTATTCGCCTTTGGTGTTAGTTGCCATA
GTGCTGTATTTGAAAATCGATGCTTTAGCCAAAAGCTGAATGACCACCGTTTCCGTAGTTTCCACTGTTTTGTCTGCATAGAATTTTCCT
GAACTACAAGCAAAAATGTATTTTGTCCAATGTCACAAAAGTGAAAATGTTACTAATCTTAGATGTGTTGCATATTTTGTGTTTTTACGT
TCCAAACTCTTTCAAAAGCTGCCGTTACAAAGCTGTTTGGCTGTATTGACAGCATGTGGTGTTTTTACAAAAGCAATTCTAGGAGAGCCA
GTGTCTACCATGAACTCCTGACATCCCCACTCCAGGGTCATTCATGACATTGAAATGGCAACTTGTACACTGTAATTCTTCGAAAAGTAA
CAGGGGATGGAAATCAGACCTGGCCGTTAGTCACTAGTGTGTAGTACCGTGATCTGAAGTAGGAAATTTAACTGACATAGAATAATTGTG
GTTTTTGAAGCAGCTACTCATTGCTTTTTCCTTTTGCTGTGAAGATCATGGATTGGGAATGTCCTCGTGAGGTGGACCTAAGGCAGTAAC
ATTTAAACTTCATGTCCTAGCACCCGCCCTCCATCTGACCCAAAGATAAAAAAGGCATCAAGCTTCATGGTTATGCCTAAGCTTAAAAAT
TCCCTTCCCCACTACTAATATTGAGTTCAGCAGGGCCCCATCTTACTTATTTTTCAAAAAAGTTATAGCTTTGAATTATAGACTATATTA
CTAAATTTGGTAAGGTAGTTCTTTGCATGAATGGGAATGTGTGTCAAAATACTTTCACAAAAGGCATGATTACAATGGAAATGCCCCTTT
GCCTCCAGTTTTGCTAACCCTAAAAAGTATTTCACTAATTTCAAGCACTGTTTACACTCAAATCCCAAAATTGGCCAAATTATATAATTC
TCTTAAATTTTCATTTCTGTAGGTGGAGATTTAACTATGGTTCTGGTGAATCATAGAAGGGAGAGACAATATTTGAGGGGAGTTTATCAG
CAGAATATCATGCCTTATGACCCCATTACTGAAACACAGACATTACAATCAGAAATAGACCTAATAATTCCAATATCCCTCCATTAACTA
GTTCCAGTGATGCTGAGAGACACAGCACCCTGTGCCAGGTATCAGAAATATAAGCCTCAGCAGAGGGTAACTGAAAACTTTCAATCAGAA
ACACTCTCCAAGGCTTATGGCTAGATTATGTAGGTCACTACCATTCAAAACTTTTCTATACAAAGGTGGAAAAGCACTCAGAATCTGGGA
ATTTTCTGGTTGGAAGAACAATGTTCTCCTTTTCCAAATTGGAATAAAGACTCAGAATTACCCATTCTTCATAATCATGTCTGATTGGTA
CATACACTCCAGGAAGTCTCAACCTAGAAACATTTCCAACCTAAGCATTTAAAGGAAAACTGGCTCATTCTTCTGACCCAAACTCAAAAA
ATATGAGTACTTGCGTACCTCCATTTCTGCATGAAGATTTTAAAACAGATTTCATTTTTTTCTGTTTATTTTGGGAAGGTGCGTGGGGGT
GTTCTTTCAAGTGATTCACATCTCAAACCCATACCACTCTCAACTTTTATTTGATGTGTTCAAAGCCAAAAAATAAAATAAAATAAAGCA
GGGCTGAACACTTAATTTGACATGAAGCTGAAGGACTGAGCAAGCCAGAGGAGAGAGGTTGAATGAAGCATAGCCTTGGCTTCATACCAC
ACTTTTTGTGCCTTGTATTATCAATGTAAATTCTGAATGTTGTACAGTAAACTTGGATGGACTTCTTAGAAAAGGCTGCACTGGCTTCTT
TTTCAGCACATGTACATATCTATAAATATATATACATATATATTTGGTAATGCCAAACAGCTCTGTTATATTGTATTGAACAAAATGGAC
GGTTTGGATGTTTTATGTCGAGTTTGCAAAAAAAAAAAAAAAAAAAAAAACTGGATGGTTGCAGACTTTTCAAGATAAATGTACAGACGT

>64229_64229_1_PEBP4-UNC5D_PEBP4_chr8_22582356_ENST00000256404_UNC5D_chr8_35406810_ENST00000287272_length(amino acids)=1022AA_BP=172
MGWTMRLVTAALLLGLMMVVTGDEDENSPCAHEALLDEDTLFCQGLEVFYPELGNIGCKVVPDCNNYRQKITSWMEPIVKFPGAVDGATY
ILVMVDPDAPSRAEPRQRFWRHWLVTDIKGADLKKGKIQGQELSAYQAPSPPAHSGFHRYQFFVYLQEGKVISLLPKENKTRGTDNGEAL
PESIPSAPGTLPHFIEEPDDAYIIKSNPIALRCKARPAMQIFFKCNGEWVHQNEHVSEETLDESSGLKVREVFINVTRQQVEDFHGPEDY
WCQCVAWSHLGTSKSRKASVRIAYLRKNFEQDPQGREVPIEGMIVLHCRPPEGVPAAEVEWLKNEEPIDSEQDENIDTRADHNLIIRQAR
LSDSGNYTCMAANIVAKRRSLSATVVVYVDGSWEVWSEWSVCSPECEHLRIRECTAPPPRNGGKFCEGLSQESENCTDGLCILDKKPLHE
IKPQSIENASDIALYSGLGAAVVAVAVLVIGVTLYRRSQSDYGVDVIDSSALTGNSLLLNSAMQPDLTVSRTYSGPICLQDPLDKELMTE
SSLFNPLSDIKVKVQSSFMVSLGVSERAEYHGKNHSRTFPHGNNHSFSTMHPRNKMPYIQNLSSLPTRTELRTTGVFGHLGGRLVMPNTG
VSLLIPHGAIPEENSWEIYMSINQGEPSLQSDGSEVLLSPEVTCGPPDMIVTTPFALTIPHCADVSSEHWNIHLKKRTQQGKWEEVMSVE
DESTSCYCLLDPFACHVLLDSFGTYALTGEPITDCAVKQLKVAVFGCMSCNSLDYNLRVYCVDNTPCAFQEVVSDERHQGGQLLEEPKLL
HFKGNTFSLQISVLDIPPFLWRIKPFTACQEVPFSRVWCSNRQPLHCAFSLERYTPTTTQLSCKICIRQLKGHEQILQVQTSILESERET
ITFFAQEDSTFPAQTGPKAFKIPYSIRQRICATFDTPNAKGKDWQMLAQKNSINRNLSYFATQSSPSAVILNLWEARHQHDGDLDSLACA

--------------------------------------------------------------
>64229_64229_2_PEBP4-UNC5D_PEBP4_chr8_22582356_ENST00000256404_UNC5D_chr8_35406810_ENST00000404895_length(transcript)=3430nt_BP=609nt
CCCAAAGTACTTGTGTCCGGGTGGTGGACTGGATTAGCTGCGGAGCCCTGGAAGCTGCCTGTCCTTCTCCCTGTGCTTAACCAGAGGTGC
CCATGGGTTGGACAATGAGGCTGGTCACAGCAGCACTGTTACTGGGTCTCATGATGGTGGTCACTGGAGACGAGGATGAGAACAGCCCGT
GTGCCCATGAGGCCCTCTTGGACGAGGACACCCTCTTTTGCCAGGGCCTTGAAGTTTTCTACCCAGAGTTGGGGAACATTGGCTGCAAGG
TTGTTCCTGATTGTAACAACTACAGACAGAAGATCACCTCCTGGATGGAGCCGATAGTCAAGTTCCCGGGGGCCGTGGACGGCGCAACCT
ATATCCTGGTGATGGTGGATCCAGATGCCCCTAGCAGAGCAGAACCCAGACAGAGATTCTGGAGACATTGGCTGGTAACAGATATCAAGG
GCGCCGACCTGAAGAAAGGGAAGATTCAGGGCCAGGAGTTATCAGCCTACCAGGCTCCCTCCCCACCGGCACACAGTGGCTTCCATCGCT
ACCAGTTCTTTGTCTATCTTCAGGAAGGAAAAGTCATCTCTCTCCTTCCCAAGGAAAACAAAACTCGAGGAACTGACAATGGCGAAGCCC
TTCCCGAATCCATCCCATCAGCTCCTGGGACACTGCCTCATTTCATAGAGGAGCCAGATGATGCTTATATTATCAAGAGCAACCCTATTG
CACTCAGGTGCAAAGCGAGGCCAGCCATGCAGATATTCTTCAAATGCAACGGCGAGTGGGTCCATCAGAACGAGCACGTCTCTGAAGAGA
CTCTGGACGAGAGCTCAGGTTTGAAGGTCCGCGAAGTGTTCATCAATGTTACTAGGCAACAGGTGGAGGACTTCCATGGGCCCGAGGACT
ATTGGTGCCAGTGTGTGGCGTGGAGCCACCTGGGTACCTCCAAGAGCAGGAAGGCCTCTGTGCGCATAGCCTATTTACGGAAAAACTTTG
AACAAGACCCACAAGGAAGGGAAGTTCCCATTGAAGGCATGATTGTACTGCACTGCCGCCCACCAGAGGGAGTCCCTGCTGCCGAGGTGG
AATGGCTGAAAAATGAAGAGCCCATTGACTCTGAACAAGACGAGAACATTGACACCAGGGCTGACCATAACCTGATCATCAGGCAGGCAC
GGCTCTCGGACTCAGGAAATTACACCTGCATGGCAGCCAACATCGTGGCTAAGAGGAGAAGCCTGTCGGCCACTGTTGTGGTCTACGTGA
ATGGAGGCTGGTCTTCCTGGACAGAGTGGTCAGCCTGCAATGTTCGCTGTGGTAGAGGATGGCAGAAACGTTCCCGGACCTGCACCAACC
CAGCTCCTCTCAATGGTGGGGCCTTTTGTGAGGGAATGTCAGTGCAGAAAATAACCTGCACTTCTCTTTGTCCTGTGGATGGGAGCTGGG
AAGTGTGGAGCGAATGGTCCGTCTGCAGTCCAGAGTGTGAACATTTGCGGATCCGGGAGTGCACAGCACCACCCCCGAGAAATGGGGGCA
AATTCTGTGAAGGTCTAAGCCAGGAATCTGAAAACTGCACAGATGGTCTTTGCATCCTAGATAAAAAACCTCTTCATGAAATAAAACCCC
AAAGCATTGAGAATGCCAGCGACATTGCTTTGTACTCGGGCTTGGGTGCTGCCGTCGTGGCCGTTGCAGTCCTGGTCATTGGTGTCACCC
TTTACAGACGGAGCCAGAGTGACTATGGCGTGGACGTCATTGACTCTTCTGCATTGACAGGTGGCTTCCAGACCTTCAACTTCAAAACAG
TCCGTCAAGGTAACTCCCTGCTCCTGAATTCTGCCATGCAGCCAGATCTGACAGTGAGCCGGACATACAGCGGACCCATCTGTCTGCAGG
ACCCTCTGGACAAGGAGCTCATGACAGAGTCCTCACTCTTTAACCCTTTGTCGGACATCAAAGTGAAAGTCCAGAGCTCGTTCATGGTTT
CCCTGGGAGTGTCTGAGAGAGCTGAGTACCACGGCAAGAATCATTCCAGGACTTTTCCCCATGGAAACAACCACAGCTTTAGTACAATGC
ATCCCAGAAATAAAATGCCCTACATCCAAAATCTGTCATCACTCCCCACAAGGACAGAACTGAGGACAACTGGTGTCTTTGGCCATTTAG
GGGGGCGCTTAGTAATGCCAAATACAGGGGTGAGCTTACTCATACCACACGGTGCCATCCCAGAGGAGAATTCTTGGGAGATTTATATGT
CCATCAACCAAGGTGAACCCAGCCTCCAGTCAGATGGCTCTGAGGTGCTCCTGAGTCCTGAAGTCACCTGTGGTCCTCCAGACATGATCG
TCACCACTCCCTTTGCATTGACCATCCCGCACTGTGCAGATGTCAGTTCTGAGCATTGGAATATCCATTTAAAGAAGAGGACACAGCAGG
GCAAATGGGAGGAAGTGATGTCAGTGGAAGATGAATCTACATCCTGTTACTGCCTTTTGGACCCCTTTGCGTGTCATGTGCTCCTGGACA
GCTTTGGGACCTATGCGCTCACTGGAGAGCCAATCACAGACTGTGCCGTGAAGCAACTGAAGGTGGCGGTTTTTGGCTGCATGTCCTGTA
ACTCCCTGGATTACAACTTGAGAGTTTACTGTGTGGACAATACCCCTTGTGCATTTCAGGAAGTGGTTTCAGATGAAAGGCATCAAGGTG
GACAGCTCCTGGAAGAACCAAAATTGCTGCATTTCAAAGGGAATACCTTTAGTCTTCAGATTTCTGTCCTTGATATTCCCCCATTCCTCT
GGAGAATTAAACCATTCACTGCCTGCCAGGAAGTCCCGTTCTCCCGCGTGTGGTGCAGTAACCGGCAGCCCCTGCACTGTGCCTTCTCCC
TGGAGCGTTATACGCCCACTACCACCCAGCTGTCCTGCAAAATCTGCATTCGGCAGCTCAAAGGCCATGAACAGATCCTCCAAGTGCAGA
CATCAATCCTAGAGAGTGAACGAGAAACCATCACTTTCTTCGCACAAGAGGACAGCACTTTCCCTGCACAGACTGGCCCCAAAGCCTTCA
AAATTCCCTACTCCATCAGACAGCGGATTTGTGCTACATTTGATACCCCCAATGCCAAAGGCAAGGACTGGCAGATGTTAGCACAGAAAA
ACAGCATCAACAGGAATTTATCTTATTTCGCTACACAAAGTAGCCCATCTGCTGTCATTTTGAACCTGTGGGAAGCTCGTCATCAGCATG
ATGGTGATCTTGACTCCCTGGCCTGTGCCCTTGAAGAGATTGGGAGGACACACACGAAACTCTCAAACATTTCAGAATCCCAGCTTGATG
AAGCCGACTTCAACTACAGCAGGCAAAATGGACTCTAGTCCACTTCCTCCCATGAGACAGAGTGATGGCCAGCTTGGGGACATTTGCTTT

>64229_64229_2_PEBP4-UNC5D_PEBP4_chr8_22582356_ENST00000256404_UNC5D_chr8_35406810_ENST00000404895_length(amino acids)=1091AA_BP=172
MGWTMRLVTAALLLGLMMVVTGDEDENSPCAHEALLDEDTLFCQGLEVFYPELGNIGCKVVPDCNNYRQKITSWMEPIVKFPGAVDGATY
ILVMVDPDAPSRAEPRQRFWRHWLVTDIKGADLKKGKIQGQELSAYQAPSPPAHSGFHRYQFFVYLQEGKVISLLPKENKTRGTDNGEAL
PESIPSAPGTLPHFIEEPDDAYIIKSNPIALRCKARPAMQIFFKCNGEWVHQNEHVSEETLDESSGLKVREVFINVTRQQVEDFHGPEDY
WCQCVAWSHLGTSKSRKASVRIAYLRKNFEQDPQGREVPIEGMIVLHCRPPEGVPAAEVEWLKNEEPIDSEQDENIDTRADHNLIIRQAR
LSDSGNYTCMAANIVAKRRSLSATVVVYVNGGWSSWTEWSACNVRCGRGWQKRSRTCTNPAPLNGGAFCEGMSVQKITCTSLCPVDGSWE
VWSEWSVCSPECEHLRIRECTAPPPRNGGKFCEGLSQESENCTDGLCILDKKPLHEIKPQSIENASDIALYSGLGAAVVAVAVLVIGVTL
YRRSQSDYGVDVIDSSALTGGFQTFNFKTVRQGNSLLLNSAMQPDLTVSRTYSGPICLQDPLDKELMTESSLFNPLSDIKVKVQSSFMVS
LGVSERAEYHGKNHSRTFPHGNNHSFSTMHPRNKMPYIQNLSSLPTRTELRTTGVFGHLGGRLVMPNTGVSLLIPHGAIPEENSWEIYMS
INQGEPSLQSDGSEVLLSPEVTCGPPDMIVTTPFALTIPHCADVSSEHWNIHLKKRTQQGKWEEVMSVEDESTSCYCLLDPFACHVLLDS
FGTYALTGEPITDCAVKQLKVAVFGCMSCNSLDYNLRVYCVDNTPCAFQEVVSDERHQGGQLLEEPKLLHFKGNTFSLQISVLDIPPFLW
RIKPFTACQEVPFSRVWCSNRQPLHCAFSLERYTPTTTQLSCKICIRQLKGHEQILQVQTSILESERETITFFAQEDSTFPAQTGPKAFK
IPYSIRQRICATFDTPNAKGKDWQMLAQKNSINRNLSYFATQSSPSAVILNLWEARHQHDGDLDSLACALEEIGRTHTKLSNISESQLDE

--------------------------------------------------------------
>64229_64229_3_PEBP4-UNC5D_PEBP4_chr8_22582356_ENST00000256404_UNC5D_chr8_35406810_ENST00000416672_length(transcript)=4028nt_BP=609nt
CCCAAAGTACTTGTGTCCGGGTGGTGGACTGGATTAGCTGCGGAGCCCTGGAAGCTGCCTGTCCTTCTCCCTGTGCTTAACCAGAGGTGC
CCATGGGTTGGACAATGAGGCTGGTCACAGCAGCACTGTTACTGGGTCTCATGATGGTGGTCACTGGAGACGAGGATGAGAACAGCCCGT
GTGCCCATGAGGCCCTCTTGGACGAGGACACCCTCTTTTGCCAGGGCCTTGAAGTTTTCTACCCAGAGTTGGGGAACATTGGCTGCAAGG
TTGTTCCTGATTGTAACAACTACAGACAGAAGATCACCTCCTGGATGGAGCCGATAGTCAAGTTCCCGGGGGCCGTGGACGGCGCAACCT
ATATCCTGGTGATGGTGGATCCAGATGCCCCTAGCAGAGCAGAACCCAGACAGAGATTCTGGAGACATTGGCTGGTAACAGATATCAAGG
GCGCCGACCTGAAGAAAGGGAAGATTCAGGGCCAGGAGTTATCAGCCTACCAGGCTCCCTCCCCACCGGCACACAGTGGCTTCCATCGCT
ACCAGTTCTTTGTCTATCTTCAGGAAGGAAAAGTCATCTCTCTCCTTCCCAAGGAAAACAAAACTCGAGGAACTGACAATGGCGAAGCCC
TTCCCGAATCCATCCCATCAGCTCCTGGGACACTGCCTCATTTCATAGAGGAGCCAGATGATGCTTATATTATCAAGAGCAACCCTATTG
CACTCAGGTGCAAAGCGAGGCCAGCCATGCAGATATTCTTCAAATGCAACGGCGAGTGGGTCCATCAGAACGAGCACGTCTCTGAAGAGA
CTCTGGACGAGAGCTCAGGTTTGAAGGTCCGCGAAGTGTTCATCAATGTTACTAGGCAACAGGTGGAGGACTTCCATGGGCCCGAGGACT
ATTGGTGCCAGTGTGTGGCGTGGAGCCACCTGGGTACCTCCAAGAGCAGGAAGGCCTCTGTGCGCATAGCCTATTTACGGAAAAACTTTG
AACAAGACCCACAAGGAAGGGAAGTTCCCATTGAAGGCATGATTGTACTGCACTGCCGCCCACCAGAGGGAGTCCCTGCTGCCGAGGTGG
AATGGCTGAAAAATGAAGAGCCCATTGACTCTGAACAAGACGAGAACATTGACACCAGGGCTGACCATAACCTGATCATCAGGCAGGCAC
GGCTCTCGGACTCAGGAAATTACACCTGCATGGCAGCCAACATCGTGGCTAAGAGGAGAAGCCTGTCGGCCACTGTTGTGGTCTACGTGA
ATGGAGGCTGGTCTTCCTGGACAGAGTGGTCAGCCTGCAATGTTCGCTGTGGTAGAGGATGGCAGAAACGTTCCCGGACCTGCACCAACC
CAGCTCCTCTCAATGGTGGGGCCTTTTGTGAGGGAATGTCAGTGCAGAAAATAACCTGCACTTCTCTTTGTCCTGTGGATGGGAGCTGGG
AAGTGTGGAGCGAATGGTCCGTCTGCAGTCCAGAGTGTGAACATTTGCGGATCCGGGAGTGCACAGCACCACCCCCGAGAAATGGGGGCA
AATTCTGTGAAGGTCTAAGCCAGGAATCTGAAAACTGCACAGATGGTCTTTGCATCCTAGATAAAAAACCTCTTCATGAAATAAAACCCC
AAAGATGGAGTAGGAGAGGCATTGAGAATGCCAGCGACATTGCTTTGTACTCGGGCTTGGGTGCTGCCGTCGTGGCCGTTGCAGTCCTGG
TCATTGGTGTCACCCTTTACAGACGGAGCCAGAGTGACTATGGCGTGGACGTCATTGACTCTTCTGCATTGACAGGTGGCTTCCAGACCT
TCAACTTCAAAACAGTCCGTCAAGGTAACTCCCTGCTCCTGAATTCTGCCATGCAGCCAGATCTGACAGTGAGCCGGACATACAGCGGAC
CCATCTGTCTGCAGGACCCTCTGGACAAGGAGCTCATGACAGAGTCCTCACTCTTTAACCCTTTGTCGGACATCAAAGTGAAAGTCCAGA
GCTCGTTCATGGTTTCCCTGGGAGTGTCTGAGAGAGCTGAGTACCACGGCAAGAATCATTCCAGGACTTTTCCCCATGGAAACAACCACA
GCTTTAGTACAATGCATCCCAGAAATAAAATGCCCTACATCCAAAATCTGTCATCACTCCCCACAAGGACAGAACTGAGGACAACTGGTG
TCTTTGGCCATTTAGGGGGGCGCTTAGTAATGCCAAATACAGGGGTGAGCTTACTCATACCACACGGTGCCATCCCAGAGGAGAATTCTT
GGGAGATTTATATGTCCATCAACCAAGGTGAACCCAGCCTCCAGTCAGATGGCTCTGAGGTGCTCCTGAGTCCTGAAGTCACCTGTGGTC
CTCCAGACATGATCGTCACCACTCCCTTTGCATTGACCATCCCGCACTGTGCAGATGTCAGTTCTGAGCATTGGAATATCCATTTAAAGA
AGAGGACACAGCAGGGCAAATGGGAGGAAGTGATGTCAGTGGAAGATGAATCTACATCCTGTTACTGCCTTTTGGACCCCTTTGCGTGTC
ATGTGCTCCTGGACAGCTTTGGGACCTATGCGCTCACTGGAGAGCCAATCACAGACTGTGCCGTGAAGCAACTGAAGGTGGCGGTTTTTG
GCTGCATGTCCTGTAACTCCCTGGATTACAACTTGAGAGTTTACTGTGTGGACAATACCCCTTGTGCATTTCAGGAAGTGGTTTCAGATG
AAAGGCATCAAGGTGGACAGCTCCTGGAAGAACCAAAATTGCTGCATTTCAAAGGGAATACCTTTAGTCTTCAGATTTCTGTCCTTGATA
TTCCCCCATTCCTCTGGAGAATTAAACCATTCACTGCCTGCCAGGAAGTCCCGTTCTCCCGCGTGTGGTGCAGTAACCGGCAGCCCCTGC
ACTGTGCCTTCTCCCTGGAGCGTTATACGCCCACTACCACCCAGCTGTCCTGCAAAATCTGCATTCGGCAGCTCAAAGGCCATGAACAGA
TCCTCCAAGTGCAGACATCAATCCTAGAGAGTGAACGAGAAACCATCACTTTCTTCGCACAAGAGGACAGCACTTTCCCTGCACAGACTG
GCCCCAAAGCCTTCAAAATTCCCTACTCCATCAGACAGCGGATTTGTGCTACATTTGATACCCCCAATGCCAAAGGCAAGGACTGGCAGA
TGTTAGCACAGAAAAACAGCATCAACAGGAATTTATCTTATTTCGCTACACAAAGTAGCCCATCTGCTGTCATTTTGAACCTGTGGGAAG
CTCGTCATCAGCATGATGGTGATCTTGACTCCCTGGCCTGTGCCCTTGAAGAGATTGGGAGGACACACACGAAACTCTCAAACATTTCAG
AATCCCAGCTTGATGAAGCCGACTTCAACTACAGCAGGCAAAATGGACTCTAGTCCACTTCCTCCCATGAGACAGAGTGATGGCCAGCTT
GGGGACATTTGCTTTAAATGGGAAAGAGGCCGCTTTCTGCCCAGTGGCGTTGGGGGAATTCAGCCTTCATTTATAATCAGTGAGATTCCC
CTGTTGAAGAAACTAAATTTTATATAGGTAAAACATGTTAATAGGGAAGAGTACAAGCTCTCTTACATATAAGAGGGCTCTACTATCTCC
TTGGAATCCACATTTGGGTTAACTCCTCAGATTTGGAGTGGCAAGGATAAAAGTGAGGGCAGAAGTAGCTGTGGGAAAAGATGAGCTATG
ATAATGCTGGGAAGGCAGAGATTGATTAAGTGCATGCTTTGAAATAGGTTTTTAATGATGTGCCCCAAAGGGCCAGCTGATTCTGGTACT
AGATTGTCAGAGTTTTCTACCAACTGGCATCTGTGATGTCAGAGATCATTGTAAAAATGGCTTTTAGACGTGAAACAGGGTTGCCAACCC
ATTTGTATGACTTCAACAACGTCAAGGAGGGCATTTAGAATTTAGAATCTGAGCACATCACACCAGCACCAGCTCCCTGTCTCTTCTAGC

>64229_64229_3_PEBP4-UNC5D_PEBP4_chr8_22582356_ENST00000256404_UNC5D_chr8_35406810_ENST00000416672_length(amino acids)=1096AA_BP=172
MGWTMRLVTAALLLGLMMVVTGDEDENSPCAHEALLDEDTLFCQGLEVFYPELGNIGCKVVPDCNNYRQKITSWMEPIVKFPGAVDGATY
ILVMVDPDAPSRAEPRQRFWRHWLVTDIKGADLKKGKIQGQELSAYQAPSPPAHSGFHRYQFFVYLQEGKVISLLPKENKTRGTDNGEAL
PESIPSAPGTLPHFIEEPDDAYIIKSNPIALRCKARPAMQIFFKCNGEWVHQNEHVSEETLDESSGLKVREVFINVTRQQVEDFHGPEDY
WCQCVAWSHLGTSKSRKASVRIAYLRKNFEQDPQGREVPIEGMIVLHCRPPEGVPAAEVEWLKNEEPIDSEQDENIDTRADHNLIIRQAR
LSDSGNYTCMAANIVAKRRSLSATVVVYVNGGWSSWTEWSACNVRCGRGWQKRSRTCTNPAPLNGGAFCEGMSVQKITCTSLCPVDGSWE
VWSEWSVCSPECEHLRIRECTAPPPRNGGKFCEGLSQESENCTDGLCILDKKPLHEIKPQRWSRRGIENASDIALYSGLGAAVVAVAVLV
IGVTLYRRSQSDYGVDVIDSSALTGGFQTFNFKTVRQGNSLLLNSAMQPDLTVSRTYSGPICLQDPLDKELMTESSLFNPLSDIKVKVQS
SFMVSLGVSERAEYHGKNHSRTFPHGNNHSFSTMHPRNKMPYIQNLSSLPTRTELRTTGVFGHLGGRLVMPNTGVSLLIPHGAIPEENSW
EIYMSINQGEPSLQSDGSEVLLSPEVTCGPPDMIVTTPFALTIPHCADVSSEHWNIHLKKRTQQGKWEEVMSVEDESTSCYCLLDPFACH
VLLDSFGTYALTGEPITDCAVKQLKVAVFGCMSCNSLDYNLRVYCVDNTPCAFQEVVSDERHQGGQLLEEPKLLHFKGNTFSLQISVLDI
PPFLWRIKPFTACQEVPFSRVWCSNRQPLHCAFSLERYTPTTTQLSCKICIRQLKGHEQILQVQTSILESERETITFFAQEDSTFPAQTG
PKAFKIPYSIRQRICATFDTPNAKGKDWQMLAQKNSINRNLSYFATQSSPSAVILNLWEARHQHDGDLDSLACALEEIGRTHTKLSNISE

--------------------------------------------------------------
>64229_64229_4_PEBP4-UNC5D_PEBP4_chr8_22582356_ENST00000256404_UNC5D_chr8_35406810_ENST00000420357_length(transcript)=3452nt_BP=609nt
CCCAAAGTACTTGTGTCCGGGTGGTGGACTGGATTAGCTGCGGAGCCCTGGAAGCTGCCTGTCCTTCTCCCTGTGCTTAACCAGAGGTGC
CCATGGGTTGGACAATGAGGCTGGTCACAGCAGCACTGTTACTGGGTCTCATGATGGTGGTCACTGGAGACGAGGATGAGAACAGCCCGT
GTGCCCATGAGGCCCTCTTGGACGAGGACACCCTCTTTTGCCAGGGCCTTGAAGTTTTCTACCCAGAGTTGGGGAACATTGGCTGCAAGG
TTGTTCCTGATTGTAACAACTACAGACAGAAGATCACCTCCTGGATGGAGCCGATAGTCAAGTTCCCGGGGGCCGTGGACGGCGCAACCT
ATATCCTGGTGATGGTGGATCCAGATGCCCCTAGCAGAGCAGAACCCAGACAGAGATTCTGGAGACATTGGCTGGTAACAGATATCAAGG
GCGCCGACCTGAAGAAAGGGAAGATTCAGGGCCAGGAGTTATCAGCCTACCAGGCTCCCTCCCCACCGGCACACAGTGGCTTCCATCGCT
ACCAGTTCTTTGTCTATCTTCAGGAAGGAAAAGTCATCTCTCTCCTTCCCAAGGAAAACAAAACTCGAGGAACTGACAATGGCGAAGCCC
TTCCCGAATCCATCCCATCAGCTCCTGGGACACTGCCTCATTTCATAGAGGAGCCAGATGATGCTTATATTATCAAGAGCAACCCTATTG
CACTCAGGTGCAAAGCGAGGCCAGCCATGCAGATATTCTTCAAATGCAACGGCGAGTGGGTCCATCAGAACGAGCACGTCTCTGAAGAGA
CTCTGGACGAGAGCTCAGGTTTGAAGGTCCGCGAAGTGTTCATCAATGTTACTAGGCAACAGGTGGAGGACTTCCATGGGCCCGAGGACT
ATTGGTGCCAGTGTGTGGCGTGGAGCCACCTGGGTACCTCCAAGAGCAGGAAGGCCTCTGTGCGCATAGCCTATTTACGGAAAAACTTTG
AACAAGACCCACAAGGAAGGGAAGTTCCCATTGAAGGCATGATTGTACTGCACTGCCGCCCACCAGAGGGAGTCCCTGCTGCCGAGGTGG
AATGGCTGAAAAATGAAGAGCCCATTGACTCTGAACAAGACGAGAACATTGACACCAGGGCTGACCATAACCTGATCATCAGGCAGGCAC
GGCTCTCGGACTCAGGAAATTACACCTGCATGGCAGCCAACATCGTGGCTAAGAGGAGAAGCCTGTCGGCCACTGTTGTGGTCTACGTGG
ATGGGAGCTGGGAAGTGTGGAGCGAATGGTCCGTCTGCAGTCCAGAGTGTGAACATTTGCGGATCCGGGAGTGCACAGCACCACCCCCGA
GAAATGGGGGCAAATTCTGTGAAGGTCTAAGCCAGGAATCTGAAAACTGCACAGATGGTCTTTGCATCCTAGGCATTGAGAATGCCAGCG
ACATTGCTTTGTACTCGGGCTTGGGTGCTGCCGTCGTGGCCGTTGCAGTCCTGGTCATTGGTGTCACCCTTTACAGACGGAGCCAGAGTG
ACTATGGCGTGGACGTCATTGACTCTTCTGCATTGACAGGTGGCTTCCAGACCTTCAACTTCAAAACAGTCCGTCAAGGTAACTCCCTGC
TCCTGAATTCTGCCATGCAGCCAGATCTGACAGTGAGCCGGACATACAGCGGACCCATCTGTCTGCAGGACCCTCTGGACAAGGAGCTCA
TGACAGAGTCCTCACTCTTTAACCCTTTGTCGGACATCAAAGTGAAAGTCCAGAGCTCGTTCATGGTTTCCCTGGGAGTGTCTGAGAGAG
CTGAGTACCACGGCAAGAATCATTCCAGGACTTTTCCCCATGGAAACAACCACAGCTTTAGTACAATGCATCCCAGAAATAAAATGCCCT
ACATCCAAAATCTGTCATCACTCCCCACAAGGACAGAACTGAGGACAACTGGTGTCTTTGGCCATTTAGGGGGGCGCTTAGTAATGCCAA
ATACAGGGGTGAGCTTACTCATACCACACGGTGCCATCCCAGAGGAGAATTCTTGGGAGATTTATATGTCCATCAACCAAGGTGAACCCA
GCCTCCAGTCAGATGGCTCTGAGGTGCTCCTGAGTCCTGAAGTCACCTGTGGTCCTCCAGACATGATCGTCACCACTCCCTTTGCATTGA
CCATCCCGCACTGTGCAGATGTCAGTTCTGAGCATTGGAATATCCATTTAAAGAAGAGGACACAGCAGGGCAAATGGGAGGAAGTGATGT
CAGTGGAAGATGAATCTACATCCTGTTACTGCCTTTTGGACCCCTTTGCGTGTCATGTGCTCCTGGACAGCTTTGGGACCTATGCGCTCA
CTGGAGAGCCAATCACAGACTGTGCCGTGAAGCAACTGAAGGTGGCGGTTTTTGGCTGCATGTCCTGTAACTCCCTGGATTACAACTTGA
GAGTTTACTGTGTGGACAATACCCCTTGTGCATTTCAGGAAGTGGTTTCAGATGAAAGGCATCAAGGTGGACAGCTCCTGGAAGAACCAA
AATTGCTGCATTTCAAAGGGAATACCTTTAGTCTTCAGATTTCTGTCCTTGATATTCCCCCATTCCTCTGGAGAATTAAACCATTCACTG
CCTGCCAGGAAGTCCCGTTCTCCCGCGTGTGGTGCAGTAACCGGCAGCCCCTGCACTGTGCCTTCTCCCTGGAGCGTTATACGCCCACTA
CCACCCAGCTGTCCTGCAAAATCTGCATTCGGCAGCTCAAAGGCCATGAACAGATCCTCCAAGTGCAGACATCAATCCTAGAGAGTGAAC
GAGAAACCATCACTTTCTTCGCACAAGAGGACAGCACTTTCCCTGCACAGACTGGCCCCAAAGCCTTCAAAATTCCCTACTCCATCAGAC
AGCGGATTTGTGCTACATTTGATACCCCCAATGCCAAAGGCAAGGACTGGCAGATGTTAGCACAGAAAAACAGCATCAACAGGAATTTAT
CTTATTTCGCTACACAAAGTAGCCCATCTGCTGTCATTTTGAACCTGTGGGAAGCTCGTCATCAGCATGATGGTGATCTTGACTCCCTGG
CCTGTGCCCTTGAAGAGATTGGGAGGACACACACGAAACTCTCAAACATTTCAGAATCCCAGCTTGATGAAGCCGACTTCAACTACAGCA
GGCAAAATGGACTCTAGTCCACTTCCTCCCATGAGACAGAGTGATGGCCAGCTTGGGGACATTTGCTTTAAATGGGAAAGAGGCCGCTTT
CTGCCCAGTGGCGTTGGGGGAATTCAGCCTTCATTTATAATCAGTGAGATTCCCCTGTTGAAGAAACTAAATTTTATATAGGTAAAACAT
GTTAATAGGGAAGAGTACAAGCTCTCTTACATATAAGAGGGCTCTACTATCTCCTTGGAATCCACATTTGGGTTAACTCCTCAGATTTGG

>64229_64229_4_PEBP4-UNC5D_PEBP4_chr8_22582356_ENST00000256404_UNC5D_chr8_35406810_ENST00000420357_length(amino acids)=1024AA_BP=172
MGWTMRLVTAALLLGLMMVVTGDEDENSPCAHEALLDEDTLFCQGLEVFYPELGNIGCKVVPDCNNYRQKITSWMEPIVKFPGAVDGATY
ILVMVDPDAPSRAEPRQRFWRHWLVTDIKGADLKKGKIQGQELSAYQAPSPPAHSGFHRYQFFVYLQEGKVISLLPKENKTRGTDNGEAL
PESIPSAPGTLPHFIEEPDDAYIIKSNPIALRCKARPAMQIFFKCNGEWVHQNEHVSEETLDESSGLKVREVFINVTRQQVEDFHGPEDY
WCQCVAWSHLGTSKSRKASVRIAYLRKNFEQDPQGREVPIEGMIVLHCRPPEGVPAAEVEWLKNEEPIDSEQDENIDTRADHNLIIRQAR
LSDSGNYTCMAANIVAKRRSLSATVVVYVDGSWEVWSEWSVCSPECEHLRIRECTAPPPRNGGKFCEGLSQESENCTDGLCILGIENASD
IALYSGLGAAVVAVAVLVIGVTLYRRSQSDYGVDVIDSSALTGGFQTFNFKTVRQGNSLLLNSAMQPDLTVSRTYSGPICLQDPLDKELM
TESSLFNPLSDIKVKVQSSFMVSLGVSERAEYHGKNHSRTFPHGNNHSFSTMHPRNKMPYIQNLSSLPTRTELRTTGVFGHLGGRLVMPN
TGVSLLIPHGAIPEENSWEIYMSINQGEPSLQSDGSEVLLSPEVTCGPPDMIVTTPFALTIPHCADVSSEHWNIHLKKRTQQGKWEEVMS
VEDESTSCYCLLDPFACHVLLDSFGTYALTGEPITDCAVKQLKVAVFGCMSCNSLDYNLRVYCVDNTPCAFQEVVSDERHQGGQLLEEPK
LLHFKGNTFSLQISVLDIPPFLWRIKPFTACQEVPFSRVWCSNRQPLHCAFSLERYTPTTTQLSCKICIRQLKGHEQILQVQTSILESER
ETITFFAQEDSTFPAQTGPKAFKIPYSIRQRICATFDTPNAKGKDWQMLAQKNSINRNLSYFATQSSPSAVILNLWEARHQHDGDLDSLA

--------------------------------------------------------------
>64229_64229_5_PEBP4-UNC5D_PEBP4_chr8_22582356_ENST00000256404_UNC5D_chr8_35406810_ENST00000453357_length(transcript)=7467nt_BP=609nt
CCCAAAGTACTTGTGTCCGGGTGGTGGACTGGATTAGCTGCGGAGCCCTGGAAGCTGCCTGTCCTTCTCCCTGTGCTTAACCAGAGGTGC
CCATGGGTTGGACAATGAGGCTGGTCACAGCAGCACTGTTACTGGGTCTCATGATGGTGGTCACTGGAGACGAGGATGAGAACAGCCCGT
GTGCCCATGAGGCCCTCTTGGACGAGGACACCCTCTTTTGCCAGGGCCTTGAAGTTTTCTACCCAGAGTTGGGGAACATTGGCTGCAAGG
TTGTTCCTGATTGTAACAACTACAGACAGAAGATCACCTCCTGGATGGAGCCGATAGTCAAGTTCCCGGGGGCCGTGGACGGCGCAACCT
ATATCCTGGTGATGGTGGATCCAGATGCCCCTAGCAGAGCAGAACCCAGACAGAGATTCTGGAGACATTGGCTGGTAACAGATATCAAGG
GCGCCGACCTGAAGAAAGGGAAGATTCAGGGCCAGGAGTTATCAGCCTACCAGGCTCCCTCCCCACCGGCACACAGTGGCTTCCATCGCT
ACCAGTTCTTTGTCTATCTTCAGGAAGGAAAAGTCATCTCTCTCCTTCCCAAGGAAAACAAAACTCGAGGAACTGACAATGGCGAAGCCC
TTCCCGAATCCATCCCATCAGCTCCTGGGACACTGCCTCATTTCATAGAGGAGCCAGATGATGCTTATATTATCAAGAGCAACCCTATTG
CACTCAGGTGCAAAGCGAGGCCAGCCATGCAGATATTCTTCAAATGCAACGGCGAGTGGGTCCATCAGAACGAGCACGTCTCTGAAGAGA
CTCTGGACGAGAGCTCAGGTTTGAAGGTCCGCGAAGTGTTCATCAATGTTACTAGGCAACAGGTGGAGGACTTCCATGGGCCCGAGGACT
ATTGGTGCCAGTGTGTGGCGTGGAGCCACCTGGGTACCTCCAAGAGCAGGAAGGCCTCTGTGCGCATAGCCTATTTACGGAAAAACTTTG
AACAAGACCCACAAGGAAGGGAAGTTCCCATTGAAGGCATGATTGTACTGCACTGCCGCCCACCAGAGGGAGTCCCTGCTGCCGAGGTGG
AATGGCTGAAAAATGAAGAGCCCATTGACTCTGAACAAGACGAGAACATTGACACCAGGGCTGACCATAACCTGATCATCAGGCAGGCAC
GGCTCTCGGACTCAGGAAATTACACCTGCATGGCAGCCAACATCGTGGCTAAGAGGAGAAGCCTGTCGGCCACTGTTGTGGTCTACGTGA
ATGGAGGCTGGTCTTCCTGGACAGAGTGGTCAGCCTGCAATGTTCGCTGTGGTAGAGGATGGCAGAAACGTTCCCGGACCTGCACCAACC
CAGCTCCTCTCAATGGTGGGGCCTTTTGTGAGGGAATGTCAGTGCAGAAAATAACCTGCACTTCTCTTTGTCCTGTGGATGGGAGCTGGG
AAGTGTGGAGCGAATGGTCCGTCTGCAGTCCAGAGTGTGAACATTTGCGGATCCGGGAGTGCACAGCACCACCCCCGAGAAATGGGGGCA
AATTCTGTGAAGGTCTAAGCCAGGAATCTGAAAACTGCACAGATGGTCTTTGCATCCTAGATAAAAAACCTCTTCATGAAATAAAACCCC
AAAGCATTGAGAATGCCAGCGACATTGCTTTGTACTCGGGCTTGGGTGCTGCCGTCGTGGCCGTTGCAGTCCTGGTCATTGGTGTCACCC
TTTACAGACGGAGCCAGAGTGACTATGGCGTGGACGTCATTGACTCTTCTGCATTGACAGGTGGCTTCCAGACCTTCAACTTCAAAACAG
TCCGTCAAGGTAACTCCCTGCTCCTGAATTCTGCCATGCAGCCAGATCTGACAGTGAGCCGGACATACAGCGGACCCATCTGTCTGCAGG
ACCCTCTGGACAAGGAGCTCATGACAGAGTCCTCACTCTTTAACCCTTTGTCGGACATCAAAGTGAAAGTCCAGAGCTCGTTCATGGTTT
CCCTGGGAGTGTCTGAGAGAGCTGAGTACCACGGCAAGAATCATTCCAGGACTTTTCCCCATGGAAACAACCACAGCTTTAGTACAATGC
ATCCCAGAAATAAAATGCCCTACATCCAAAATCTGTCATCACTCCCCACAAGGACAGAACTGAGGACAACTGGTGTCTTTGGCCATTTAG
GGGGGCGCTTAGTAATGCCAAATACAGGGGTGAGCTTACTCATACCACACGGTGCCATCCCAGAGGAGAATTCTTGGGAGATTTATATGT
CCATCAACCAAGGTGAACCCAGCCTCCAGTCAGATGGCTCTGAGGTGCTCCTGAGTCCTGAAGTCACCTGTGGTCCTCCAGACATGATCG
TCACCACTCCCTTTGCATTGACCATCCCGCACTGTGCAGATGTCAGTTCTGAGCATTGGAATATCCATTTAAAGAAGAGGACACAGCAGG
GCAAATGGGAGGAAGTGATGTCAGTGGAAGATGAATCTACATCCTGTTACTGCCTTTTGGACCCCTTTGCGTGTCATGTGCTCCTGGACA
GCTTTGGGACCTATGCGCTCACTGGAGAGCCAATCACAGACTGTGCCGTGAAGCAACTGAAGGTGGCGGTTTTTGGCTGCATGTCCTGTA
ACTCCCTGGATTACAACTTGAGAGTTTACTGTGTGGACAATACCCCTTGTGCATTTCAGGAAGTGGTTTCAGATGAAAGGCATCAAGGTG
GACAGCTCCTGGAAGAACCAAAATTGCTGCATTTCAAAGGGAATACCTTTAGTCTTCAGATTTCTGTCCTTGATATTCCCCCATTCCTCT
GGAGAATTAAACCATTCACTGCCTGCCAGGAAGTCCCGTTCTCCCGCGTGTGGTGCAGTAACCGGCAGCCCCTGCACTGTGCCTTCTCCC
TGGAGCGTTATACGCCCACTACCACCCAGCTGTCCTGCAAAATCTGCATTCGGCAGCTCAAAGGCCATGAACAGATCCTCCAAGTGCAGA
CATCAATCCTAGAGAGTGAACGAGAAACCATCACTTTCTTCGCACAAGAGGACAGCACTTTCCCTGCACAGACTGGCCCCAAAGCCTTCA
AAATTCCCTACTCCATCAGACAGCGGATTTGTGCTACATTTGATACCCCCAATGCCAAAGGCAAGGACTGGCAGATGTTAGCACAGAAAA
ACAGCATCAACAGGAATTTATCTTATTTCGCTACACAAAGTAGCCCATCTGCTGTCATTTTGAACCTGTGGGAAGCTCGTCATCAGCATG
ATGGTGATCTTGACTCCCTGGCCTGTGCCCTTGAAGAGATTGGGAGGACACACACGAAACTCTCAAACATTTCAGAATCCCAGCTTGATG
AAGCCGACTTCAACTACAGCAGGCAAAATGGACTCTAGTCCACTTCCTCCCATGAGACAGAGTGATGGCCAGCTTGGGGACATTTGCTTT
AAATGGGAAAGAGGCCGCTTTCTGCCCAGTGGCGTTGGGGGAATTCAGCCTTCATTTATAATCAGTGAGATTCCCCTGTTGAAGAAACTA
AATTTTATATAGGTAAAACATGTTAATAGGGAAGAGTACAAGCTCTCTTACATATAAGAGGGCTCTACTATCTCCTTGGAATCCACATTT
GGGTTAACTCCTCAGATTTGGAGTGGCAAGGATAAAAGTGAGGGCAGAAGTAGCTGTGGGAAAAGATGAGCTATGATAATGCTGGGAAGG
CAGAGATTGATTAAGTGCATGCTTTGAAATAGGTTTTTAATGATGTGCCCCAAAGGGCCAGCTGATTCTGGTACTAGATTGTCAGAGTTT
TCTACCAACTGGCATCTGTGATGTCAGAGATCATTGTAAAAATGGCTTTTAGACGTGAAACAGGGTTGCCAACCCATTTGTATGACTTCA
ACAACGTCAAGGAGGGCATTTAGAATTTAGAATCTGAGCACATCACACCAGCACCAGCTCCCTGTCTCTTCTAGCCACTTAATGGAGACA
CAATGGAGAGGTAAGACAGACCACAAACTAGTTCTTATAGTGTACTCCACCTTTTACTTTTTTCCTGAGACAAATCTACCCTTATTCTTT
CTTCCTCTTCCTTACCCCTTGCAGTAGGGAGGTATCAAGGAGCATAATTAAACTTGTCAATACGGAAAGTTGTTTTTTCTAACACAACAA
AGTGGGACCATCTCTATTCCCATCTAAGCCACTCAAATTGCTGAGTGCTATTAGAACACAGCTTATTACATGGATATGGGGACAGGAGAG
ATTAAAGCAGGTTCAAAAACACATGAACTGCAGATGCCATAGGCCTCAAATCAGCTGTAATTCTAGGAGACACGTGTTGATCTAGTTATC
TAACATTGTTGTTATAAGAAAATGAGTTTACTGCATTTTTCAATCCAGATTCTTGAAATTGTCTAACATGTGGGTACTGTGTCATCACAA
AATCTCTCAGTAAGGCTATATGTGATCCTCATTTTGCCTCTTGGGAAATTAGCAGATAGTCTTTGCTCTAAATGATATCTGAGTAAATAG
ACTTGAGGAATCCTCTACCACAGTGTCCCTGAAACCACATGCATCATTCAGGAAGCCTTCACCCTGTGACTATTCAGCCTCCCTGAATAT
GCTTTCTCTATAGAACCACTAACATATGGCTATTGCTCTATGATTTTTTTTTTTACATTAGGAGGCAGTGATATTGTGGAAGATTGAAAT
CCACAGATAATTCATGACCCTCATCTTATCACTTTACTCCATCTTTTTATCCTATTAAATTATTTTTGACAAGATGTCCTGGTAGACTAA
AGGTGAACAGATTTGCTCTTGCTCATCTTCTGGTGGATATTTTAACTTGCTATTCACAATCAGGACAACCAAAGTCAAGGACCCAGATGA
ACCACAAGGCAGCTAGTCAGCTACTTAGAGGTTGGTTACATTCGAATAAAAAGTAGTCAGGGAATGGGGGAGGTGGGGAGTTGGGGAGTA
CTTGGCAGTTGGGATATGATCCATTTTTTTAAACAAGTTTTTTGTAGATCCCTTGTAAAATAATAATAATAATGTTGTGAATCTCCATGC
CAAGTGAAAAAGGCCTAAAGATGAGTTGAATTTGTGATACCATGGGTAAGGCATGGAAGAACTCTTGAATGTGTTGGCCATTTTCTCTAA
CTAACATGTGGTATGTATGGTCCCCTATATTAGATAGAAGTCTTTGCTACATGTAATTCAAAAGCATCTCGCTTTTCTCAGGAACCAAAG
GCTTATGATGTAGGACAAAGAAATCATCTTAGAACTGTCAAGCATATTTTCACAATACCATGTCAAGATCAGGAAAACACCCTTTTGCTA
GTGTGCTTAACTTATTTATTTCTTCTAGGAAACAATAGATAAACAGCATGAAAATGTAAATCATCTGGCATCACTGATAGAATTTCTGAA
AGAGAAAGAGAAGTAGATGGTCAACCAGTCACTAGTTGGTTGGCATGAGGTGGTGTGCAGAGGAAAGCTGCATTCACTATTGAGTAAAAA
CTTGTAGAAAGCACATTATAGAGCTTATGTTGGAATCCATCTTGGAGGATTTTTGTTTTAAACTGTCTTTAGCATTTTCCCTCTTCCCTT
CTAATGGGCATTATAATTGTTTCATCTACTCTGTGAATCTACATAGGTCTTTTTTTTTAGATGTTTGATACATTTTAAGTATTTTTAAAT
AGATGAAAATTCTAAATGATTTTCCCTCAAATCTATCTAGATTATTTTAAGATGAGACAAGATTATTGTCAATCCCTGAATGTCTGGAGT
TACCTCCCATGGATTTTTTTTTCCTTTGGCCTGGGTTTTATAAACAACTTGAACATCATATCATATAGGATAACAAAGGAGGAAGTTAAC
TTAATTCACCTCAGACTTCAGCCTAAGATTCAATCAAATTCATCCTTCAGCCTGTCTTGTTTCTTCTTTATGTTTCTTTTACTTATTGCT
GCTAGGATCCTACATAGGATTTCTATAGAAATGTATGAAATTCTGTGGTCACTGCATGTCAGGATTGCACAGTATGTTACAATACAATTT
CAAAGAGAACCCACATTTGTGAGATTTACAGACCAAGGTGTGGTGGAGGAGGTAGAATTGCAGATCAGATAAAAAGTGAGCTTACACTTG
AACTTAGTTATTCACTGTGACCTAAATTTAGTCCTATTGTAATATGTGCCTGTCACAACACAAATACCCCTCTTGAAAGAGATTTACTCA
TCTATCCAAGCACTTAATTTGGAAATTTTATTGTCCTATTGCAAAATGAAACAAAATTAAAAGTGGCCTCGAGTACTTGGTAAGTTACTT
AAAATTTTTACAAAAATATCCCACTCAATGCCAAATCTTTCAGTCCTCAAAGGCATTTAAGTCCAATAGTCATGCTTTAAATATGGCTTT
AAATTATGCCACCAAAATGGTGCACTTCACAGATTCACCAGACTGTAGCATCATAAAGTTAATTTACAGTTTTTACAACATTGCTTCTAC
ATTCTTACTGGTTTACATTAAAATCCTTTAAGCCAAAAGGAAGCTTGCTCTATGGATTTAAATGCAAACTTCATTTACCAGTGCAGGAAG
TCTCATAAAACTCAGATGTACTCCCACAAAAATTTTATTGGCCTTTTTGTAAGAGATGAAAAAGAATTGACACAGTTCTCTTTAAAGAGA
AGAACTTTTTTATTATTATTTTTATCTCCAACTGCAGGTGGTGTCTTTTGCCAAGGTCTCTGTATTTTTCTTTCAGTTGTCTTTGGGAGG
GGATGTTAAGTCAAATCACTAAAACAGGGTTCTCTTTGGATTAAAAGTTCTGGATTTATTGCAACTATTTTCCTTGAGAAACATTCTCAG
CATCAGGATTGATAAACAAATGTAGATGATTAAAATAGGATAATTGGTTTTAGATAATATCTTCTACTGCCAAACTTCTGGCAAATTTAC
CTGTGAATTTCAAAATGTTATAAAATCTCTTGATATGCTTTTGTTTTTCCTTTTAGCCATTTTCTCTTCAATTTCTTAGTCCCTCTGCCC
TCTGTAAATGTGTTGAGTGATATAGCTATCAGATGTATTGAAGGCAAAGTTCTCGCAGAGGTCTCTGTTCCAGCTCTGTAAAGGTCACAG
GAATCGTGAAGGAGCTGAGAAATCTTCCTCTCCGGCCCACTGTCTGTGGCCCATTGTCATTGTTTCCTCATGAAACATTGCAGAGTTTGA
ATCCTCAGTAACTCTCATTGACTGGATTAGAGGTGATGGCCACAGCAAATGGGAGAGCAAAATGTTGGCCTACAGAGAATGACACAATTT
TATTCGCCTTTGGTGTTAGTTGCCATAGTGCTGTATTTGAAAATCGATGCTTTAGCCAAAAGCTGAATGACCACCGTTTCCGTAGTTTCC

>64229_64229_5_PEBP4-UNC5D_PEBP4_chr8_22582356_ENST00000256404_UNC5D_chr8_35406810_ENST00000453357_length(amino acids)=1091AA_BP=172
MGWTMRLVTAALLLGLMMVVTGDEDENSPCAHEALLDEDTLFCQGLEVFYPELGNIGCKVVPDCNNYRQKITSWMEPIVKFPGAVDGATY
ILVMVDPDAPSRAEPRQRFWRHWLVTDIKGADLKKGKIQGQELSAYQAPSPPAHSGFHRYQFFVYLQEGKVISLLPKENKTRGTDNGEAL
PESIPSAPGTLPHFIEEPDDAYIIKSNPIALRCKARPAMQIFFKCNGEWVHQNEHVSEETLDESSGLKVREVFINVTRQQVEDFHGPEDY
WCQCVAWSHLGTSKSRKASVRIAYLRKNFEQDPQGREVPIEGMIVLHCRPPEGVPAAEVEWLKNEEPIDSEQDENIDTRADHNLIIRQAR
LSDSGNYTCMAANIVAKRRSLSATVVVYVNGGWSSWTEWSACNVRCGRGWQKRSRTCTNPAPLNGGAFCEGMSVQKITCTSLCPVDGSWE
VWSEWSVCSPECEHLRIRECTAPPPRNGGKFCEGLSQESENCTDGLCILDKKPLHEIKPQSIENASDIALYSGLGAAVVAVAVLVIGVTL
YRRSQSDYGVDVIDSSALTGGFQTFNFKTVRQGNSLLLNSAMQPDLTVSRTYSGPICLQDPLDKELMTESSLFNPLSDIKVKVQSSFMVS
LGVSERAEYHGKNHSRTFPHGNNHSFSTMHPRNKMPYIQNLSSLPTRTELRTTGVFGHLGGRLVMPNTGVSLLIPHGAIPEENSWEIYMS
INQGEPSLQSDGSEVLLSPEVTCGPPDMIVTTPFALTIPHCADVSSEHWNIHLKKRTQQGKWEEVMSVEDESTSCYCLLDPFACHVLLDS
FGTYALTGEPITDCAVKQLKVAVFGCMSCNSLDYNLRVYCVDNTPCAFQEVVSDERHQGGQLLEEPKLLHFKGNTFSLQISVLDIPPFLW
RIKPFTACQEVPFSRVWCSNRQPLHCAFSLERYTPTTTQLSCKICIRQLKGHEQILQVQTSILESERETITFFAQEDSTFPAQTGPKAFK
IPYSIRQRICATFDTPNAKGKDWQMLAQKNSINRNLSYFATQSSPSAVILNLWEARHQHDGDLDSLACALEEIGRTHTKLSNISESQLDE

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Fusion Gene PPI Analysis for PEBP4-UNC5D


check button Go to ChiPPI (Chimeric Protein-Protein interactions) to see the chimeric PPI interaction in

ChiPPI page.


check button Protein-protein interactors with each fusion partner protein in wild-type (BIOGRID-3.4.160)
HgeneHgene's interactorsTgeneTgene's interactors


check button - Retained PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenStill interaction with


check button - Lost PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


check button - Retained PPIs, but lost function due to frame-shift fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


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Related Drugs for PEBP4-UNC5D


check button Drugs targeting genes involved in this fusion gene.
(DrugBank Version 5.1.8 2021-05-08)
PartnerGeneUniProtAccDrugBank IDDrug nameDrug activityDrug typeDrug status

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Related Diseases for PEBP4-UNC5D


check button Diseases associated with fusion partners.
(DisGeNet 4.0)
PartnerGeneDisease IDDisease name# pubmedsSource