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Center for Computational Systems Medicine
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Fusion Gene Summary

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Fusion Gene ORF analysis

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Fusion Genomic Features

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Fusion Protein Features

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Fusion Gene Sequence

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Fusion Gene PPI analysis

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Related Drugs

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Related Diseases

Fusion gene:PFKM-ZDHHC13 (FusionGDB2 ID:64457)

Fusion Gene Summary for PFKM-ZDHHC13

check button Fusion gene summary
Fusion gene informationFusion gene name: PFKM-ZDHHC13
Fusion gene ID: 64457
HgeneTgene
Gene symbol

PFKM

ZDHHC13

Gene ID

5213

54503

Gene namephosphofructokinase, musclezinc finger DHHC-type palmitoyltransferase 13
SynonymsATP-PFK|GSD7|PFK-1|PFK-A|PFK1|PFKA|PFKX|PPP1R122HIP14L|HIP3RP
Cytomap

12q13.11

11p15.1

Type of geneprotein-codingprotein-coding
DescriptionATP-dependent 6-phosphofructokinase, muscle type6-phosphofructo-1-kinase6-phosphofructokinase type A6-phosphofructokinase, muscle typephosphofructo-1-kinase isozyme Aphosphofructokinase 1phosphofructokinase, polypeptide Xphosphofructokinase-Mphosppalmitoyltransferase ZDHHC13DHHC-13HIP14-related proteinhuntingtin interacting protein HIP3RPhuntingtin-interacting protein 14-related proteinprobable palmitoyltransferase ZDHHC13putative MAPK-activating protein PM03putative NF-kappa-B-activating p
Modification date2020032920200313
UniProtAcc..
Ensembl transtripts involved in fusion geneENST00000312352, ENST00000340802, 
ENST00000359794, ENST00000395233, 
ENST00000547587, ENST00000551804, 
ENST00000551548, 		ENST00000532812, 
ENST00000399351, ENST00000446113, 
Fusion gene scores* DoF score4 X 4 X 2=321 X 1 X 1=1
# samples 41
** MAII scorelog2(4/32*10)=0.321928094887362
effective Gene in Pan-Cancer Fusion Genes (eGinPCFGs).
DoF>8 and MAII>0		log2(1/1*10)=3.32192809488736
Context

PubMed: PFKM [Title/Abstract] AND ZDHHC13 [Title/Abstract] AND fusion [Title/Abstract]

Most frequent breakpointPFKM(48534654)-ZDHHC13(19186598), # samples:2
Anticipated loss of major functional domain due to fusion event.
* DoF score (Degree of Frequency) = # partners X # break points X # cancer types
** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10)

check button Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez
PartnerGeneGO IDGO termPubMed ID
HgenePFKM

GO:0006002

fructose 6-phosphate metabolic process

6444721


check buttonFusion gene breakpoints across PFKM (5'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.
all structure

check buttonFusion gene breakpoints across ZDHHC13 (3'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.
all structure

check button Fusion gene information from two resources (ChiTars 5.0 and ChimerDB 4.0)
* All genome coordinats were lifted-over on hg19.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
SourceDiseaseSampleHgeneHchrHbpHstrandTgeneTchrTbpTstrand
ChimerDB4ESCATCGA-IG-A51DPFKMchr12

48534654

+ZDHHC13chr11

19186598

+


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Fusion Gene ORF analysis for PFKM-ZDHHC13

check button Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
ORFHenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrand
5CDS-intronENST00000312352ENST00000532812PFKMchr12

48534654

+ZDHHC13chr11

19186598

+
5CDS-intronENST00000340802ENST00000532812PFKMchr12

48534654

+ZDHHC13chr11

19186598

+
5CDS-intronENST00000359794ENST00000532812PFKMchr12

48534654

+ZDHHC13chr11

19186598

+
5CDS-intronENST00000395233ENST00000532812PFKMchr12

48534654

+ZDHHC13chr11

19186598

+
5CDS-intronENST00000547587ENST00000532812PFKMchr12

48534654

+ZDHHC13chr11

19186598

+
5CDS-intronENST00000551804ENST00000532812PFKMchr12

48534654

+ZDHHC13chr11

19186598

+
In-frameENST00000312352ENST00000399351PFKMchr12

48534654

+ZDHHC13chr11

19186598

+
In-frameENST00000312352ENST00000446113PFKMchr12

48534654

+ZDHHC13chr11

19186598

+
In-frameENST00000340802ENST00000399351PFKMchr12

48534654

+ZDHHC13chr11

19186598

+
In-frameENST00000340802ENST00000446113PFKMchr12

48534654

+ZDHHC13chr11

19186598

+
In-frameENST00000359794ENST00000399351PFKMchr12

48534654

+ZDHHC13chr11

19186598

+
In-frameENST00000359794ENST00000446113PFKMchr12

48534654

+ZDHHC13chr11

19186598

+
In-frameENST00000395233ENST00000399351PFKMchr12

48534654

+ZDHHC13chr11

19186598

+
In-frameENST00000395233ENST00000446113PFKMchr12

48534654

+ZDHHC13chr11

19186598

+
In-frameENST00000547587ENST00000399351PFKMchr12

48534654

+ZDHHC13chr11

19186598

+
In-frameENST00000547587ENST00000446113PFKMchr12

48534654

+ZDHHC13chr11

19186598

+
In-frameENST00000551804ENST00000399351PFKMchr12

48534654

+ZDHHC13chr11

19186598

+
In-frameENST00000551804ENST00000446113PFKMchr12

48534654

+ZDHHC13chr11

19186598

+
intron-3CDSENST00000551548ENST00000399351PFKMchr12

48534654

+ZDHHC13chr11

19186598

+
intron-3CDSENST00000551548ENST00000446113PFKMchr12

48534654

+ZDHHC13chr11

19186598

+
intron-intronENST00000551548ENST00000532812PFKMchr12

48534654

+ZDHHC13chr11

19186598

+

check buttonORFfinder result based on the fusion transcript sequence of in-frame fusion genes.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandSeq length
(transcript)		BP loci
(transcript)		Predicted start
(transcript)		Predicted stop
(transcript)		Seq length
(amino acids)
ENST00000340802PFKMchr1248534654+ENST00000446113ZDHHC13chr1119186598+280617782242350708
ENST00000340802PFKMchr1248534654+ENST00000399351ZDHHC13chr1119186598+280617782242350708
ENST00000359794PFKMchr1248534654+ENST00000446113ZDHHC13chr1119186598+25581530332102689
ENST00000359794PFKMchr1248534654+ENST00000399351ZDHHC13chr1119186598+25581530332102689
ENST00000395233PFKMchr1248534654+ENST00000446113ZDHHC13chr1119186598+23131285371857606
ENST00000395233PFKMchr1248534654+ENST00000399351ZDHHC13chr1119186598+23131285371857606
ENST00000551804PFKMchr1248534654+ENST00000446113ZDHHC13chr1119186598+242713991511971606
ENST00000551804PFKMchr1248534654+ENST00000399351ZDHHC13chr1119186598+242713991511971606
ENST00000547587PFKMchr1248534654+ENST00000446113ZDHHC13chr1119186598+249714691282041637
ENST00000547587PFKMchr1248534654+ENST00000399351ZDHHC13chr1119186598+249714691282041637
ENST00000312352PFKMchr1248534654+ENST00000446113ZDHHC13chr1119186598+24081380391952637
ENST00000312352PFKMchr1248534654+ENST00000399351ZDHHC13chr1119186598+24081380391952637

check buttonDeepORF prediction of the coding potential based on the fusion transcript sequence of in-frame fusion genes. DeepORF is a coding potential classifier based on convolutional neural network by comparing the real Ribo-seq data. If the no-coding score < 0.5 and coding score > 0.5, then the in-frame fusion transcript is predicted as being likely translated.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandNo-coding scoreCoding score
ENST00000340802ENST00000446113PFKMchr1248534654+ZDHHC13chr1119186598+0.0013243190.99867564
ENST00000340802ENST00000399351PFKMchr1248534654+ZDHHC13chr1119186598+0.0013243190.99867564
ENST00000359794ENST00000446113PFKMchr1248534654+ZDHHC13chr1119186598+0.0009989540.9990011
ENST00000359794ENST00000399351PFKMchr1248534654+ZDHHC13chr1119186598+0.0009989540.9990011
ENST00000395233ENST00000446113PFKMchr1248534654+ZDHHC13chr1119186598+0.0006806650.9993193
ENST00000395233ENST00000399351PFKMchr1248534654+ZDHHC13chr1119186598+0.0006806650.9993193
ENST00000551804ENST00000446113PFKMchr1248534654+ZDHHC13chr1119186598+0.0004758150.99952424
ENST00000551804ENST00000399351PFKMchr1248534654+ZDHHC13chr1119186598+0.0004758150.99952424
ENST00000547587ENST00000446113PFKMchr1248534654+ZDHHC13chr1119186598+0.000790630.9992093
ENST00000547587ENST00000399351PFKMchr1248534654+ZDHHC13chr1119186598+0.000790630.9992093
ENST00000312352ENST00000446113PFKMchr1248534654+ZDHHC13chr1119186598+0.0007923510.9992077
ENST00000312352ENST00000399351PFKMchr1248534654+ZDHHC13chr1119186598+0.0007923510.9992077

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Fusion Genomic Features for PFKM-ZDHHC13


check buttonFusionAI prediction of the potential fusion gene breakpoint based on the pre-mature RNA sequence context (+/- 5kb of individual partner genes, total 20kb length sequence). FusionAI is a fusion gene breakpoint classifier based on convolutional neural network by comparing the fusion positive and negative sequence context of ~ 20K fusion gene data. From here, we can have the relative potentency of the 20K genomic sequence how individual sequnce will be likely used as the gene fusion breakpoints.
HgeneHchrHbpHstrandTgeneTchrTbpTstrand1-pp (fusion gene breakpoint)
PFKMchr1248534654+ZDHHC13chr1119186598+0.988980650.011019321
PFKMchr1248534654+ZDHHC13chr1119186598+0.988980650.011019321

check buttonDistribution of 44 human genomic features loci across 20kb length fusion breakpoint regions. We integrated a total of 44 different types of human genomic feature loci information across five big categories including virus integration sites, repeats, structural variants, chromatin states, and gene expression regulation. More details are in help page.
genomic feature

check buttonDistribution of 44 human genomic features loci across 20kb length fusion breakpoint regions that are ovelapped with the top 1% feature importance score regions. More details are in help page.
genomic feature of top 1%

Top

Fusion Protein Features for PFKM-ZDHHC13


check button Four levels of functional features of fusion genes
Go to FGviewer search page for the most frequent breakpoint (https://ccsmweb.uth.edu/FGviewer/chr12:48534654/chr11:19186598)
- FGviewer provides the online visualization of the retention search of the protein functional features across DNA, RNA, protein, and pathological levels.
- How to search
1. Put your fusion gene symbol.
2. Press the tab key until there will be shown the breakpoint information filled.
4. Go down and press 'Search' tab twice.
4. Go down to have the hyperlink of the search result.
5. Click the hyperlink.
6. See the FGviewer result for your fusion gene.
FGviewer

check buttonMain function of each fusion partner protein. (from UniProt)
HgeneTgene
..
FUNCTION: Transcriptional activator which is required for calcium-dependent dendritic growth and branching in cortical neurons. Recruits CREB-binding protein (CREBBP) to nuclear bodies. Component of the CREST-BRG1 complex, a multiprotein complex that regulates promoter activation by orchestrating a calcium-dependent release of a repressor complex and a recruitment of an activator complex. In resting neurons, transcription of the c-FOS promoter is inhibited by BRG1-dependent recruitment of a phospho-RB1-HDAC1 repressor complex. Upon calcium influx, RB1 is dephosphorylated by calcineurin, which leads to release of the repressor complex. At the same time, there is increased recruitment of CREBBP to the promoter by a CREST-dependent mechanism, which leads to transcriptional activation. The CREST-BRG1 complex also binds to the NR2B promoter, and activity-dependent induction of NR2B expression involves a release of HDAC1 and recruitment of CREBBP (By similarity). {ECO:0000250}.FUNCTION: Transcriptional activator which is required for calcium-dependent dendritic growth and branching in cortical neurons. Recruits CREB-binding protein (CREBBP) to nuclear bodies. Component of the CREST-BRG1 complex, a multiprotein complex that regulates promoter activation by orchestrating a calcium-dependent release of a repressor complex and a recruitment of an activator complex. In resting neurons, transcription of the c-FOS promoter is inhibited by BRG1-dependent recruitment of a phospho-RB1-HDAC1 repressor complex. Upon calcium influx, RB1 is dephosphorylated by calcineurin, which leads to release of the repressor complex. At the same time, there is increased recruitment of CREBBP to the promoter by a CREST-dependent mechanism, which leads to transcriptional activation. The CREST-BRG1 complex also binds to the NR2B promoter, and activity-dependent induction of NR2B expression involves a release of HDAC1 and recruitment of CREBBP (By similarity). {ECO:0000250}.

check buttonRetention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at

download page


* Minus value of BPloci means that the break pointn is located before the CDS.
- In-frame and retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
HgenePFKMchr12:48534654chr11:19186598ENST00000312352+1423118_121447781.0Nucleotide bindingATP
HgenePFKMchr12:48534654chr11:19186598ENST00000312352+142388_89447781.0Nucleotide bindingATP
HgenePFKMchr12:48534654chr11:19186598ENST00000340802+1625118_121518852.0Nucleotide bindingATP
HgenePFKMchr12:48534654chr11:19186598ENST00000340802+162588_89518852.0Nucleotide bindingATP
HgenePFKMchr12:48534654chr11:19186598ENST00000359794+1423118_121447781.0Nucleotide bindingATP
HgenePFKMchr12:48534654chr11:19186598ENST00000359794+142388_89447781.0Nucleotide bindingATP
HgenePFKMchr12:48534654chr11:19186598ENST00000395233+1322118_121416750.0Nucleotide bindingATP
HgenePFKMchr12:48534654chr11:19186598ENST00000395233+132288_89416750.0Nucleotide bindingATP
HgenePFKMchr12:48534654chr11:19186598ENST00000547587+1322118_121447781.0Nucleotide bindingATP
HgenePFKMchr12:48534654chr11:19186598ENST00000547587+132288_89447781.0Nucleotide bindingATP
HgenePFKMchr12:48534654chr11:19186598ENST00000551804+1322118_121416750.0Nucleotide bindingATP
HgenePFKMchr12:48534654chr11:19186598ENST00000551804+132288_89416750.0Nucleotide bindingATP
HgenePFKMchr12:48534654chr11:19186598ENST00000312352+1423164_166447781.0RegionSubstrate binding
HgenePFKMchr12:48534654chr11:19186598ENST00000312352+1423208_210447781.0RegionSubstrate binding
HgenePFKMchr12:48534654chr11:19186598ENST00000312352+1423298_301447781.0RegionSubstrate binding
HgenePFKMchr12:48534654chr11:19186598ENST00000312352+14232_390447781.0RegionNote=N-terminal catalytic PFK domain 1
HgenePFKMchr12:48534654chr11:19186598ENST00000312352+1423391_401447781.0RegionNote=Interdomain linker
HgenePFKMchr12:48534654chr11:19186598ENST00000340802+1625164_166518852.0RegionSubstrate binding
HgenePFKMchr12:48534654chr11:19186598ENST00000340802+1625208_210518852.0RegionSubstrate binding
HgenePFKMchr12:48534654chr11:19186598ENST00000340802+1625298_301518852.0RegionSubstrate binding
HgenePFKMchr12:48534654chr11:19186598ENST00000340802+16252_390518852.0RegionNote=N-terminal catalytic PFK domain 1
HgenePFKMchr12:48534654chr11:19186598ENST00000340802+1625391_401518852.0RegionNote=Interdomain linker
HgenePFKMchr12:48534654chr11:19186598ENST00000359794+1423164_166447781.0RegionSubstrate binding
HgenePFKMchr12:48534654chr11:19186598ENST00000359794+1423208_210447781.0RegionSubstrate binding
HgenePFKMchr12:48534654chr11:19186598ENST00000359794+1423298_301447781.0RegionSubstrate binding
HgenePFKMchr12:48534654chr11:19186598ENST00000359794+14232_390447781.0RegionNote=N-terminal catalytic PFK domain 1
HgenePFKMchr12:48534654chr11:19186598ENST00000359794+1423391_401447781.0RegionNote=Interdomain linker
HgenePFKMchr12:48534654chr11:19186598ENST00000395233+1322164_166416750.0RegionSubstrate binding
HgenePFKMchr12:48534654chr11:19186598ENST00000395233+1322208_210416750.0RegionSubstrate binding
HgenePFKMchr12:48534654chr11:19186598ENST00000395233+1322298_301416750.0RegionSubstrate binding
HgenePFKMchr12:48534654chr11:19186598ENST00000395233+13222_390416750.0RegionNote=N-terminal catalytic PFK domain 1
HgenePFKMchr12:48534654chr11:19186598ENST00000395233+1322391_401416750.0RegionNote=Interdomain linker
HgenePFKMchr12:48534654chr11:19186598ENST00000547587+1322164_166447781.0RegionSubstrate binding
HgenePFKMchr12:48534654chr11:19186598ENST00000547587+1322208_210447781.0RegionSubstrate binding
HgenePFKMchr12:48534654chr11:19186598ENST00000547587+1322298_301447781.0RegionSubstrate binding
HgenePFKMchr12:48534654chr11:19186598ENST00000547587+13222_390447781.0RegionNote=N-terminal catalytic PFK domain 1
HgenePFKMchr12:48534654chr11:19186598ENST00000547587+1322391_401447781.0RegionNote=Interdomain linker
HgenePFKMchr12:48534654chr11:19186598ENST00000551804+1322164_166416750.0RegionSubstrate binding
HgenePFKMchr12:48534654chr11:19186598ENST00000551804+1322208_210416750.0RegionSubstrate binding
HgenePFKMchr12:48534654chr11:19186598ENST00000551804+1322298_301416750.0RegionSubstrate binding
HgenePFKMchr12:48534654chr11:19186598ENST00000551804+13222_390416750.0RegionNote=N-terminal catalytic PFK domain 1
HgenePFKMchr12:48534654chr11:19186598ENST00000551804+1322391_401416750.0RegionNote=Interdomain linker
TgeneZDHHC13chr12:48534654chr11:19186598ENST000003993511016328_391302493.0Compositional biasNote=Phe-rich
TgeneZDHHC13chr12:48534654chr11:19186598ENST000003993511016426_476302493.0DomainDHHC
TgeneZDHHC13chr12:48534654chr11:19186598ENST000003993511016313_320302493.0Topological domainLumenal
TgeneZDHHC13chr12:48534654chr11:19186598ENST000003993511016342_347302493.0Topological domainCytoplasmic
TgeneZDHHC13chr12:48534654chr11:19186598ENST000003993511016369_370302493.0Topological domainLumenal
TgeneZDHHC13chr12:48534654chr11:19186598ENST000003993511016392_470302493.0Topological domainCytoplasmic
TgeneZDHHC13chr12:48534654chr11:19186598ENST000003993511016492_518302493.0Topological domainLumenal
TgeneZDHHC13chr12:48534654chr11:19186598ENST000003993511016540_622302493.0Topological domainCytoplasmic
TgeneZDHHC13chr12:48534654chr11:19186598ENST000004461131117492_518432623.0Topological domainLumenal
TgeneZDHHC13chr12:48534654chr11:19186598ENST000004461131117540_622432623.0Topological domainCytoplasmic
TgeneZDHHC13chr12:48534654chr11:19186598ENST000003993511016321_341302493.0TransmembraneHelical
TgeneZDHHC13chr12:48534654chr11:19186598ENST000003993511016348_368302493.0TransmembraneHelical
TgeneZDHHC13chr12:48534654chr11:19186598ENST000003993511016371_391302493.0TransmembraneHelical
TgeneZDHHC13chr12:48534654chr11:19186598ENST000003993511016471_491302493.0TransmembraneHelical
TgeneZDHHC13chr12:48534654chr11:19186598ENST000003993511016519_539302493.0TransmembraneHelical
TgeneZDHHC13chr12:48534654chr11:19186598ENST000004461131117471_491432623.0TransmembraneHelical
TgeneZDHHC13chr12:48534654chr11:19186598ENST000004461131117519_539432623.0TransmembraneHelical

- In-frame and not-retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
HgenePFKMchr12:48534654chr11:19186598ENST00000312352+1423402_780447781.0RegionNote=C-terminal regulatory PFK domain 2
HgenePFKMchr12:48534654chr11:19186598ENST00000312352+1423528_532447781.0RegionFructose 2%2C6-bisphosphate binding%3B allosteric activator
HgenePFKMchr12:48534654chr11:19186598ENST00000312352+1423573_575447781.0RegionFructose 2%2C6-bisphosphate binding%3B allosteric activator
HgenePFKMchr12:48534654chr11:19186598ENST00000312352+1423661_664447781.0RegionFructose 2%2C6-bisphosphate binding%3B allosteric activator
HgenePFKMchr12:48534654chr11:19186598ENST00000340802+1625402_780518852.0RegionNote=C-terminal regulatory PFK domain 2
HgenePFKMchr12:48534654chr11:19186598ENST00000340802+1625528_532518852.0RegionFructose 2%2C6-bisphosphate binding%3B allosteric activator
HgenePFKMchr12:48534654chr11:19186598ENST00000340802+1625573_575518852.0RegionFructose 2%2C6-bisphosphate binding%3B allosteric activator
HgenePFKMchr12:48534654chr11:19186598ENST00000340802+1625661_664518852.0RegionFructose 2%2C6-bisphosphate binding%3B allosteric activator
HgenePFKMchr12:48534654chr11:19186598ENST00000359794+1423402_780447781.0RegionNote=C-terminal regulatory PFK domain 2
HgenePFKMchr12:48534654chr11:19186598ENST00000359794+1423528_532447781.0RegionFructose 2%2C6-bisphosphate binding%3B allosteric activator
HgenePFKMchr12:48534654chr11:19186598ENST00000359794+1423573_575447781.0RegionFructose 2%2C6-bisphosphate binding%3B allosteric activator
HgenePFKMchr12:48534654chr11:19186598ENST00000359794+1423661_664447781.0RegionFructose 2%2C6-bisphosphate binding%3B allosteric activator
HgenePFKMchr12:48534654chr11:19186598ENST00000395233+1322402_780416750.0RegionNote=C-terminal regulatory PFK domain 2
HgenePFKMchr12:48534654chr11:19186598ENST00000395233+1322528_532416750.0RegionFructose 2%2C6-bisphosphate binding%3B allosteric activator
HgenePFKMchr12:48534654chr11:19186598ENST00000395233+1322573_575416750.0RegionFructose 2%2C6-bisphosphate binding%3B allosteric activator
HgenePFKMchr12:48534654chr11:19186598ENST00000395233+1322661_664416750.0RegionFructose 2%2C6-bisphosphate binding%3B allosteric activator
HgenePFKMchr12:48534654chr11:19186598ENST00000547587+1322402_780447781.0RegionNote=C-terminal regulatory PFK domain 2
HgenePFKMchr12:48534654chr11:19186598ENST00000547587+1322528_532447781.0RegionFructose 2%2C6-bisphosphate binding%3B allosteric activator
HgenePFKMchr12:48534654chr11:19186598ENST00000547587+1322573_575447781.0RegionFructose 2%2C6-bisphosphate binding%3B allosteric activator
HgenePFKMchr12:48534654chr11:19186598ENST00000547587+1322661_664447781.0RegionFructose 2%2C6-bisphosphate binding%3B allosteric activator
HgenePFKMchr12:48534654chr11:19186598ENST00000551804+1322402_780416750.0RegionNote=C-terminal regulatory PFK domain 2
HgenePFKMchr12:48534654chr11:19186598ENST00000551804+1322528_532416750.0RegionFructose 2%2C6-bisphosphate binding%3B allosteric activator
HgenePFKMchr12:48534654chr11:19186598ENST00000551804+1322573_575416750.0RegionFructose 2%2C6-bisphosphate binding%3B allosteric activator
HgenePFKMchr12:48534654chr11:19186598ENST00000551804+1322661_664416750.0RegionFructose 2%2C6-bisphosphate binding%3B allosteric activator
TgeneZDHHC13chr12:48534654chr11:19186598ENST000004461131117328_391432623.0Compositional biasNote=Phe-rich
TgeneZDHHC13chr12:48534654chr11:19186598ENST000004461131117426_476432623.0DomainDHHC
TgeneZDHHC13chr12:48534654chr11:19186598ENST000003993511016115_144302493.0RepeatANK 3
TgeneZDHHC13chr12:48534654chr11:19186598ENST000003993511016148_177302493.0RepeatANK 4
TgeneZDHHC13chr12:48534654chr11:19186598ENST000003993511016181_211302493.0RepeatANK 5
TgeneZDHHC13chr12:48534654chr11:19186598ENST000003993511016216_245302493.0RepeatANK 6
TgeneZDHHC13chr12:48534654chr11:19186598ENST000003993511016249_277302493.0RepeatANK 7
TgeneZDHHC13chr12:48534654chr11:19186598ENST00000399351101643_78302493.0RepeatANK 1
TgeneZDHHC13chr12:48534654chr11:19186598ENST00000399351101681_110302493.0RepeatANK 2
TgeneZDHHC13chr12:48534654chr11:19186598ENST000004461131117115_144432623.0RepeatANK 3
TgeneZDHHC13chr12:48534654chr11:19186598ENST000004461131117148_177432623.0RepeatANK 4
TgeneZDHHC13chr12:48534654chr11:19186598ENST000004461131117181_211432623.0RepeatANK 5
TgeneZDHHC13chr12:48534654chr11:19186598ENST000004461131117216_245432623.0RepeatANK 6
TgeneZDHHC13chr12:48534654chr11:19186598ENST000004461131117249_277432623.0RepeatANK 7
TgeneZDHHC13chr12:48534654chr11:19186598ENST00000446113111743_78432623.0RepeatANK 1
TgeneZDHHC13chr12:48534654chr11:19186598ENST00000446113111781_110432623.0RepeatANK 2
TgeneZDHHC13chr12:48534654chr11:19186598ENST0000039935110161_291302493.0Topological domainCytoplasmic
TgeneZDHHC13chr12:48534654chr11:19186598ENST0000044611311171_291432623.0Topological domainCytoplasmic
TgeneZDHHC13chr12:48534654chr11:19186598ENST000004461131117313_320432623.0Topological domainLumenal
TgeneZDHHC13chr12:48534654chr11:19186598ENST000004461131117342_347432623.0Topological domainCytoplasmic
TgeneZDHHC13chr12:48534654chr11:19186598ENST000004461131117369_370432623.0Topological domainLumenal
TgeneZDHHC13chr12:48534654chr11:19186598ENST000004461131117392_470432623.0Topological domainCytoplasmic
TgeneZDHHC13chr12:48534654chr11:19186598ENST000003993511016292_312302493.0TransmembraneHelical
TgeneZDHHC13chr12:48534654chr11:19186598ENST000004461131117292_312432623.0TransmembraneHelical
TgeneZDHHC13chr12:48534654chr11:19186598ENST000004461131117321_341432623.0TransmembraneHelical
TgeneZDHHC13chr12:48534654chr11:19186598ENST000004461131117348_368432623.0TransmembraneHelical
TgeneZDHHC13chr12:48534654chr11:19186598ENST000004461131117371_391432623.0TransmembraneHelical


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Fusion Gene Sequence for PFKM-ZDHHC13


check button For in-frame fusion transcripts, we provide the fusion transcript sequences and fusion amino acid sequences. To have fusion amino acid sequence, we ran ORFfinder and chose the longest ORF among the all predicted ones.
>64457_64457_1_PFKM-ZDHHC13_PFKM_chr12_48534654_ENST00000312352_ZDHHC13_chr11_19186598_ENST00000399351_length(transcript)=2408nt_BP=1380nt
AGACTTGGTATAGTGGGAGAGCCTGACTGAGAGTGGATCATGACCCATGAAGAGCACCATGCAGCCAAAACCCTGGGGATTGGCAAAGCC
ATTGCTGTCTTAACCTCTGGTGGAGATGCCCAAGGTATGAATGCTGCTGTCAGGGCTGTGGTTCGAGTTGGTATCTTCACCGGTGCCCGT
GTCTTCTTTGTCCATGAGGGTTATCAAGGCCTGGTGGATGGTGGAGATCACATCAAGGAAGCCACCTGGGAGAGCGTTTCGATGATGCTT
CAGCTGGGAGGCACGGTGATTGGAAGTGCCCGGTGCAAGGACTTTCGGGAACGAGAAGGACGACTCCGAGCTGCCTACAACCTGGTGAAG
CGTGGGATCACCAATCTCTGTGTCATTGGGGGTGATGGCAGCCTCACTGGGGCTGACACCTTCCGTTCTGAGTGGAGTGACTTGTTGAGT
GACCTCCAGAAAGCAGGTAAGATCACAGATGAGGAGGCTACGAAGTCCAGCTACCTGAACATTGTGGGCCTGGTTGGGTCAATTGACAAT
GACTTCTGTGGCACCGATATGACCATTGGCACTGACTCTGCCCTGCATCGGATCATGGAAATTGTAGATGCCATCACTACCACTGCCCAG
AGCCACCAGAGGACATTTGTGTTAGAAGTAATGGGCCGCCACTGTGGATACCTGGCCCTTGTCACCTCTCTGTCCTGTGGGGCCGACTGG
GTTTTTATTCCTGAATGTCCACCAGATGACGACTGGGAGGAACACCTTTGTCGCCGACTCAGCGAGACAAGGACCCGTGGTTCTCGTCTC
AACATCATCATTGTGGCTGAGGGTGCAATTGACAAGAATGGAAAACCAATCACCTCAGAAGACATCAAGAATCTGGTGGTTAAGCGTCTG
GGATATGACACCCGGGTTACTGTCTTGGGGCATGTGCAGAGGGGTGGGACGCCATCAGCCTTTGACAGAATTCTGGGCAGCAGGATGGGT
GTGGAAGCAGTGATGGCACTTTTGGAGGGGACCCCAGATACCCCAGCCTGTGTAGTGAGCCTCTCTGGTAACCAGGCTGTGCGCCTGCCC
CTCATGGAATGTGTCCAGGTGACCAAAGATGTGACCAAGGCCATGGATGAGAAGAAATTTGACGAAGCCCTGAAGCTGAGAGGCCGGAGC
TTCATGAACAACTGGGAGGTGTACAAGCTTCTAGCTCATGTCAGACCCCCGGTATCTAAGAGTGGTTCGCACACAGTGGCTGTGATGAAC
GTGGGGGCTCCGGCTGCAGGCATGAATGCTGCTGTTCGCTCCACTGTGAGGATTGGCCTTATCCAGGGCAACCGAGTGCTCGTTGTCCAT
GATGGTTTCGAGGGCCTGGCCAAGGGGCAGATAAGGAAGCCATTAAGGTCACTCCACTGCCATGTATGCAACTGCTGTGTGGCTCGATAT
GATCAACACTGCCTGTGGACTGGACGGTGCATAGGTTTTGGCAACCATCACTATTACATATTCTTCTTGTTTTTCCTTTCCATGGTATGT
GGCTGGATTATATATGGATCTTTCATCTATTTGTCCAGTCATTGTGCCACAACATTCAAAGAAGATGGATTATGGACTTACCTCAATCAG
ATTGTGGCCTGTTCCCCTTGGGTTTTATATATCTTGATGCTAGCAACTTTCCATTTCTCATGGTCAACATTTTTATTATTAAATCAACTC
TTTCAGATTGCCTTTCTGGGCCTGACCTCCCATGAGAGAATCAGCCTGCAGAAGCAGAGCAAGCATATGAAACAGACGTTGTCCCTCAGG
AAGACACCATACAATCTTGGATTCATGCAGAACCTGGCAGATTTCTTTCAGTGTGGCTGCTTTGGCTTGGTGAAGCCCTGTGTGGTAGAT
TGGACATCACAGTACACCATGGTCTTTCACCCAGCCAGGGAGAAGGTTCTTCGCTCAGTATGAAGAAAAGCAACCCAAAACTCTCAATCT
GATTTGTTTTTGTTTATGTCGATGCCCTGTAGTTTGAAAGTGAAGTAAAGATTTAGAATTCACCTAAGTCCAAAGGAAAACACGTGGTTT
TTAAAGCCATTAGGTAAAAAAAGTTCTCAATAAAGGCATTACAATTTTTTAGGTTTAGAAAGATGGACTTTTCTGATAAATCTTGGCAGA
CATCTAAAAAAAAAACCATATTTTTCACAAGAAAATGCAAGTTACTTTTTTTGGAAATAATACTCACTGATTATGGATAAAATGGAATAT
TTTCAGATACTATATTGGCTGTTTCAAAATAGTACTATTCTTTAAACTTGTAATTTTTGCTAAGTTATTTGTCTTTGTTGTATCTATAAA

>64457_64457_1_PFKM-ZDHHC13_PFKM_chr12_48534654_ENST00000312352_ZDHHC13_chr11_19186598_ENST00000399351_length(amino acids)=637AA_BP=447
MTHEEHHAAKTLGIGKAIAVLTSGGDAQGMNAAVRAVVRVGIFTGARVFFVHEGYQGLVDGGDHIKEATWESVSMMLQLGGTVIGSARCK
DFREREGRLRAAYNLVKRGITNLCVIGGDGSLTGADTFRSEWSDLLSDLQKAGKITDEEATKSSYLNIVGLVGSIDNDFCGTDMTIGTDS
ALHRIMEIVDAITTTAQSHQRTFVLEVMGRHCGYLALVTSLSCGADWVFIPECPPDDDWEEHLCRRLSETRTRGSRLNIIIVAEGAIDKN
GKPITSEDIKNLVVKRLGYDTRVTVLGHVQRGGTPSAFDRILGSRMGVEAVMALLEGTPDTPACVVSLSGNQAVRLPLMECVQVTKDVTK
AMDEKKFDEALKLRGRSFMNNWEVYKLLAHVRPPVSKSGSHTVAVMNVGAPAAGMNAAVRSTVRIGLIQGNRVLVVHDGFEGLAKGQIRK
PLRSLHCHVCNCCVARYDQHCLWTGRCIGFGNHHYYIFFLFFLSMVCGWIIYGSFIYLSSHCATTFKEDGLWTYLNQIVACSPWVLYILM
LATFHFSWSTFLLLNQLFQIAFLGLTSHERISLQKQSKHMKQTLSLRKTPYNLGFMQNLADFFQCGCFGLVKPCVVDWTSQYTMVFHPAR

--------------------------------------------------------------
>64457_64457_2_PFKM-ZDHHC13_PFKM_chr12_48534654_ENST00000312352_ZDHHC13_chr11_19186598_ENST00000446113_length(transcript)=2408nt_BP=1380nt
AGACTTGGTATAGTGGGAGAGCCTGACTGAGAGTGGATCATGACCCATGAAGAGCACCATGCAGCCAAAACCCTGGGGATTGGCAAAGCC
ATTGCTGTCTTAACCTCTGGTGGAGATGCCCAAGGTATGAATGCTGCTGTCAGGGCTGTGGTTCGAGTTGGTATCTTCACCGGTGCCCGT
GTCTTCTTTGTCCATGAGGGTTATCAAGGCCTGGTGGATGGTGGAGATCACATCAAGGAAGCCACCTGGGAGAGCGTTTCGATGATGCTT
CAGCTGGGAGGCACGGTGATTGGAAGTGCCCGGTGCAAGGACTTTCGGGAACGAGAAGGACGACTCCGAGCTGCCTACAACCTGGTGAAG
CGTGGGATCACCAATCTCTGTGTCATTGGGGGTGATGGCAGCCTCACTGGGGCTGACACCTTCCGTTCTGAGTGGAGTGACTTGTTGAGT
GACCTCCAGAAAGCAGGTAAGATCACAGATGAGGAGGCTACGAAGTCCAGCTACCTGAACATTGTGGGCCTGGTTGGGTCAATTGACAAT
GACTTCTGTGGCACCGATATGACCATTGGCACTGACTCTGCCCTGCATCGGATCATGGAAATTGTAGATGCCATCACTACCACTGCCCAG
AGCCACCAGAGGACATTTGTGTTAGAAGTAATGGGCCGCCACTGTGGATACCTGGCCCTTGTCACCTCTCTGTCCTGTGGGGCCGACTGG
GTTTTTATTCCTGAATGTCCACCAGATGACGACTGGGAGGAACACCTTTGTCGCCGACTCAGCGAGACAAGGACCCGTGGTTCTCGTCTC
AACATCATCATTGTGGCTGAGGGTGCAATTGACAAGAATGGAAAACCAATCACCTCAGAAGACATCAAGAATCTGGTGGTTAAGCGTCTG
GGATATGACACCCGGGTTACTGTCTTGGGGCATGTGCAGAGGGGTGGGACGCCATCAGCCTTTGACAGAATTCTGGGCAGCAGGATGGGT
GTGGAAGCAGTGATGGCACTTTTGGAGGGGACCCCAGATACCCCAGCCTGTGTAGTGAGCCTCTCTGGTAACCAGGCTGTGCGCCTGCCC
CTCATGGAATGTGTCCAGGTGACCAAAGATGTGACCAAGGCCATGGATGAGAAGAAATTTGACGAAGCCCTGAAGCTGAGAGGCCGGAGC
TTCATGAACAACTGGGAGGTGTACAAGCTTCTAGCTCATGTCAGACCCCCGGTATCTAAGAGTGGTTCGCACACAGTGGCTGTGATGAAC
GTGGGGGCTCCGGCTGCAGGCATGAATGCTGCTGTTCGCTCCACTGTGAGGATTGGCCTTATCCAGGGCAACCGAGTGCTCGTTGTCCAT
GATGGTTTCGAGGGCCTGGCCAAGGGGCAGATAAGGAAGCCATTAAGGTCACTCCACTGCCATGTATGCAACTGCTGTGTGGCTCGATAT
GATCAACACTGCCTGTGGACTGGACGGTGCATAGGTTTTGGCAACCATCACTATTACATATTCTTCTTGTTTTTCCTTTCCATGGTATGT
GGCTGGATTATATATGGATCTTTCATCTATTTGTCCAGTCATTGTGCCACAACATTCAAAGAAGATGGATTATGGACTTACCTCAATCAG
ATTGTGGCCTGTTCCCCTTGGGTTTTATATATCTTGATGCTAGCAACTTTCCATTTCTCATGGTCAACATTTTTATTATTAAATCAACTC
TTTCAGATTGCCTTTCTGGGCCTGACCTCCCATGAGAGAATCAGCCTGCAGAAGCAGAGCAAGCATATGAAACAGACGTTGTCCCTCAGG
AAGACACCATACAATCTTGGATTCATGCAGAACCTGGCAGATTTCTTTCAGTGTGGCTGCTTTGGCTTGGTGAAGCCCTGTGTGGTAGAT
TGGACATCACAGTACACCATGGTCTTTCACCCAGCCAGGGAGAAGGTTCTTCGCTCAGTATGAAGAAAAGCAACCCAAAACTCTCAATCT
GATTTGTTTTTGTTTATGTCGATGCCCTGTAGTTTGAAAGTGAAGTAAAGATTTAGAATTCACCTAAGTCCAAAGGAAAACACGTGGTTT
TTAAAGCCATTAGGTAAAAAAAGTTCTCAATAAAGGCATTACAATTTTTTAGGTTTAGAAAGATGGACTTTTCTGATAAATCTTGGCAGA
CATCTAAAAAAAAAACCATATTTTTCACAAGAAAATGCAAGTTACTTTTTTTGGAAATAATACTCACTGATTATGGATAAAATGGAATAT
TTTCAGATACTATATTGGCTGTTTCAAAATAGTACTATTCTTTAAACTTGTAATTTTTGCTAAGTTATTTGTCTTTGTTGTATCTATAAA

>64457_64457_2_PFKM-ZDHHC13_PFKM_chr12_48534654_ENST00000312352_ZDHHC13_chr11_19186598_ENST00000446113_length(amino acids)=637AA_BP=447
MTHEEHHAAKTLGIGKAIAVLTSGGDAQGMNAAVRAVVRVGIFTGARVFFVHEGYQGLVDGGDHIKEATWESVSMMLQLGGTVIGSARCK
DFREREGRLRAAYNLVKRGITNLCVIGGDGSLTGADTFRSEWSDLLSDLQKAGKITDEEATKSSYLNIVGLVGSIDNDFCGTDMTIGTDS
ALHRIMEIVDAITTTAQSHQRTFVLEVMGRHCGYLALVTSLSCGADWVFIPECPPDDDWEEHLCRRLSETRTRGSRLNIIIVAEGAIDKN
GKPITSEDIKNLVVKRLGYDTRVTVLGHVQRGGTPSAFDRILGSRMGVEAVMALLEGTPDTPACVVSLSGNQAVRLPLMECVQVTKDVTK
AMDEKKFDEALKLRGRSFMNNWEVYKLLAHVRPPVSKSGSHTVAVMNVGAPAAGMNAAVRSTVRIGLIQGNRVLVVHDGFEGLAKGQIRK
PLRSLHCHVCNCCVARYDQHCLWTGRCIGFGNHHYYIFFLFFLSMVCGWIIYGSFIYLSSHCATTFKEDGLWTYLNQIVACSPWVLYILM
LATFHFSWSTFLLLNQLFQIAFLGLTSHERISLQKQSKHMKQTLSLRKTPYNLGFMQNLADFFQCGCFGLVKPCVVDWTSQYTMVFHPAR

--------------------------------------------------------------
>64457_64457_3_PFKM-ZDHHC13_PFKM_chr12_48534654_ENST00000340802_ZDHHC13_chr11_19186598_ENST00000399351_length(transcript)=2806nt_BP=1778nt
GCTTCCGCCCAGTCCAGCCCGGGCCGGCTGACCGGGTCCGACACAGTCTCCTGGACCAGGCTCCCTCCATCCTCACCCCTCCCCCAGCTT
CCCGCCGCCACTCACCGAACCGGAACCGGCTGCCATGCGAAGGGGTTTCCGGCCGGGCGCGGAACGCAAAACCCGGGAACCGCCGCGAAC
CGGAACCGCCTTCACAGCACCGGAAGAGTCGCTAGGAGGCAGCCATGCATAAAGACGAGTTTCATCTGAAATTTTTCATGTGTGTGATTC
AGTCTCGCCAGTTAGTCAGGACTCCTCAGAGAACAGCTGGGGAAGCTTCTACTTCCAGCATGCTCATACCAAAGCCACCACCAAAGACAG
ACATCTTGAAGAGTCTAGATACTATGGATGATCCAGACACCGTGGGAAGCATACCTGTTTTCAAAACTGAGTGGATCATGACCCATGAAG
AGCACCATGCAGCCAAAACCCTGGGGATTGGCAAAGCCATTGCTGTCTTAACCTCTGGTGGAGATGCCCAAGGTATGAATGCTGCTGTCA
GGGCTGTGGTTCGAGTTGGTATCTTCACCGGTGCCCGTGTCTTCTTTGTCCATGAGGGTTATCAAGGCCTGGTGGATGGTGGAGATCACA
TCAAGGAAGCCACCTGGGAGAGCGTTTCGATGATGCTTCAGCTGGGAGGCACGGTGATTGGAAGTGCCCGGTGCAAGGACTTTCGGGAAC
GAGAAGGACGACTCCGAGCTGCCTACAACCTGGTGAAGCGTGGGATCACCAATCTCTGTGTCATTGGGGGTGATGGCAGCCTCACTGGGG
CTGACACCTTCCGTTCTGAGTGGAGTGACTTGTTGAGTGACCTCCAGAAAGCAGGTAAGATCACAGATGAGGAGGCTACGAAGTCCAGCT
ACCTGAACATTGTGGGCCTGGTTGGGTCAATTGACAATGACTTCTGTGGCACCGATATGACCATTGGCACTGACTCTGCCCTGCATCGGA
TCATGGAAATTGTAGATGCCATCACTACCACTGCCCAGAGCCACCAGAGGACATTTGTGTTAGAAGTAATGGGCCGCCACTGTGGATACC
TGGCCCTTGTCACCTCTCTGTCCTGTGGGGCCGACTGGGTTTTTATTCCTGAATGTCCACCAGATGACGACTGGGAGGAACACCTTTGTC
GCCGACTCAGCGAGACAAGGACCCGTGGTTCTCGTCTCAACATCATCATTGTGGCTGAGGGTGCAATTGACAAGAATGGAAAACCAATCA
CCTCAGAAGACATCAAGAATCTGGTGGTTAAGCGTCTGGGATATGACACCCGGGTTACTGTCTTGGGGCATGTGCAGAGGGGTGGGACGC
CATCAGCCTTTGACAGAATTCTGGGCAGCAGGATGGGTGTGGAAGCAGTGATGGCACTTTTGGAGGGGACCCCAGATACCCCAGCCTGTG
TAGTGAGCCTCTCTGGTAACCAGGCTGTGCGCCTGCCCCTCATGGAATGTGTCCAGGTGACCAAAGATGTGACCAAGGCCATGGATGAGA
AGAAATTTGACGAAGCCCTGAAGCTGAGAGGCCGGAGCTTCATGAACAACTGGGAGGTGTACAAGCTTCTAGCTCATGTCAGACCCCCGG
TATCTAAGAGTGGTTCGCACACAGTGGCTGTGATGAACGTGGGGGCTCCGGCTGCAGGCATGAATGCTGCTGTTCGCTCCACTGTGAGGA
TTGGCCTTATCCAGGGCAACCGAGTGCTCGTTGTCCATGATGGTTTCGAGGGCCTGGCCAAGGGGCAGATAAGGAAGCCATTAAGGTCAC
TCCACTGCCATGTATGCAACTGCTGTGTGGCTCGATATGATCAACACTGCCTGTGGACTGGACGGTGCATAGGTTTTGGCAACCATCACT
ATTACATATTCTTCTTGTTTTTCCTTTCCATGGTATGTGGCTGGATTATATATGGATCTTTCATCTATTTGTCCAGTCATTGTGCCACAA
CATTCAAAGAAGATGGATTATGGACTTACCTCAATCAGATTGTGGCCTGTTCCCCTTGGGTTTTATATATCTTGATGCTAGCAACTTTCC
ATTTCTCATGGTCAACATTTTTATTATTAAATCAACTCTTTCAGATTGCCTTTCTGGGCCTGACCTCCCATGAGAGAATCAGCCTGCAGA
AGCAGAGCAAGCATATGAAACAGACGTTGTCCCTCAGGAAGACACCATACAATCTTGGATTCATGCAGAACCTGGCAGATTTCTTTCAGT
GTGGCTGCTTTGGCTTGGTGAAGCCCTGTGTGGTAGATTGGACATCACAGTACACCATGGTCTTTCACCCAGCCAGGGAGAAGGTTCTTC
GCTCAGTATGAAGAAAAGCAACCCAAAACTCTCAATCTGATTTGTTTTTGTTTATGTCGATGCCCTGTAGTTTGAAAGTGAAGTAAAGAT
TTAGAATTCACCTAAGTCCAAAGGAAAACACGTGGTTTTTAAAGCCATTAGGTAAAAAAAGTTCTCAATAAAGGCATTACAATTTTTTAG
GTTTAGAAAGATGGACTTTTCTGATAAATCTTGGCAGACATCTAAAAAAAAAACCATATTTTTCACAAGAAAATGCAAGTTACTTTTTTT
GGAAATAATACTCACTGATTATGGATAAAATGGAATATTTTCAGATACTATATTGGCTGTTTCAAAATAGTACTATTCTTTAAACTTGTA
ATTTTTGCTAAGTTATTTGTCTTTGTTGTATCTATAAATATGTAAAAAATATTTAAATAGATGTACCTGTTTTGCTTTCACACTTAATAA

>64457_64457_3_PFKM-ZDHHC13_PFKM_chr12_48534654_ENST00000340802_ZDHHC13_chr11_19186598_ENST00000399351_length(amino acids)=708AA_BP=518
MHKDEFHLKFFMCVIQSRQLVRTPQRTAGEASTSSMLIPKPPPKTDILKSLDTMDDPDTVGSIPVFKTEWIMTHEEHHAAKTLGIGKAIA
VLTSGGDAQGMNAAVRAVVRVGIFTGARVFFVHEGYQGLVDGGDHIKEATWESVSMMLQLGGTVIGSARCKDFREREGRLRAAYNLVKRG
ITNLCVIGGDGSLTGADTFRSEWSDLLSDLQKAGKITDEEATKSSYLNIVGLVGSIDNDFCGTDMTIGTDSALHRIMEIVDAITTTAQSH
QRTFVLEVMGRHCGYLALVTSLSCGADWVFIPECPPDDDWEEHLCRRLSETRTRGSRLNIIIVAEGAIDKNGKPITSEDIKNLVVKRLGY
DTRVTVLGHVQRGGTPSAFDRILGSRMGVEAVMALLEGTPDTPACVVSLSGNQAVRLPLMECVQVTKDVTKAMDEKKFDEALKLRGRSFM
NNWEVYKLLAHVRPPVSKSGSHTVAVMNVGAPAAGMNAAVRSTVRIGLIQGNRVLVVHDGFEGLAKGQIRKPLRSLHCHVCNCCVARYDQ
HCLWTGRCIGFGNHHYYIFFLFFLSMVCGWIIYGSFIYLSSHCATTFKEDGLWTYLNQIVACSPWVLYILMLATFHFSWSTFLLLNQLFQ

--------------------------------------------------------------
>64457_64457_4_PFKM-ZDHHC13_PFKM_chr12_48534654_ENST00000340802_ZDHHC13_chr11_19186598_ENST00000446113_length(transcript)=2806nt_BP=1778nt
GCTTCCGCCCAGTCCAGCCCGGGCCGGCTGACCGGGTCCGACACAGTCTCCTGGACCAGGCTCCCTCCATCCTCACCCCTCCCCCAGCTT
CCCGCCGCCACTCACCGAACCGGAACCGGCTGCCATGCGAAGGGGTTTCCGGCCGGGCGCGGAACGCAAAACCCGGGAACCGCCGCGAAC
CGGAACCGCCTTCACAGCACCGGAAGAGTCGCTAGGAGGCAGCCATGCATAAAGACGAGTTTCATCTGAAATTTTTCATGTGTGTGATTC
AGTCTCGCCAGTTAGTCAGGACTCCTCAGAGAACAGCTGGGGAAGCTTCTACTTCCAGCATGCTCATACCAAAGCCACCACCAAAGACAG
ACATCTTGAAGAGTCTAGATACTATGGATGATCCAGACACCGTGGGAAGCATACCTGTTTTCAAAACTGAGTGGATCATGACCCATGAAG
AGCACCATGCAGCCAAAACCCTGGGGATTGGCAAAGCCATTGCTGTCTTAACCTCTGGTGGAGATGCCCAAGGTATGAATGCTGCTGTCA
GGGCTGTGGTTCGAGTTGGTATCTTCACCGGTGCCCGTGTCTTCTTTGTCCATGAGGGTTATCAAGGCCTGGTGGATGGTGGAGATCACA
TCAAGGAAGCCACCTGGGAGAGCGTTTCGATGATGCTTCAGCTGGGAGGCACGGTGATTGGAAGTGCCCGGTGCAAGGACTTTCGGGAAC
GAGAAGGACGACTCCGAGCTGCCTACAACCTGGTGAAGCGTGGGATCACCAATCTCTGTGTCATTGGGGGTGATGGCAGCCTCACTGGGG
CTGACACCTTCCGTTCTGAGTGGAGTGACTTGTTGAGTGACCTCCAGAAAGCAGGTAAGATCACAGATGAGGAGGCTACGAAGTCCAGCT
ACCTGAACATTGTGGGCCTGGTTGGGTCAATTGACAATGACTTCTGTGGCACCGATATGACCATTGGCACTGACTCTGCCCTGCATCGGA
TCATGGAAATTGTAGATGCCATCACTACCACTGCCCAGAGCCACCAGAGGACATTTGTGTTAGAAGTAATGGGCCGCCACTGTGGATACC
TGGCCCTTGTCACCTCTCTGTCCTGTGGGGCCGACTGGGTTTTTATTCCTGAATGTCCACCAGATGACGACTGGGAGGAACACCTTTGTC
GCCGACTCAGCGAGACAAGGACCCGTGGTTCTCGTCTCAACATCATCATTGTGGCTGAGGGTGCAATTGACAAGAATGGAAAACCAATCA
CCTCAGAAGACATCAAGAATCTGGTGGTTAAGCGTCTGGGATATGACACCCGGGTTACTGTCTTGGGGCATGTGCAGAGGGGTGGGACGC
CATCAGCCTTTGACAGAATTCTGGGCAGCAGGATGGGTGTGGAAGCAGTGATGGCACTTTTGGAGGGGACCCCAGATACCCCAGCCTGTG
TAGTGAGCCTCTCTGGTAACCAGGCTGTGCGCCTGCCCCTCATGGAATGTGTCCAGGTGACCAAAGATGTGACCAAGGCCATGGATGAGA
AGAAATTTGACGAAGCCCTGAAGCTGAGAGGCCGGAGCTTCATGAACAACTGGGAGGTGTACAAGCTTCTAGCTCATGTCAGACCCCCGG
TATCTAAGAGTGGTTCGCACACAGTGGCTGTGATGAACGTGGGGGCTCCGGCTGCAGGCATGAATGCTGCTGTTCGCTCCACTGTGAGGA
TTGGCCTTATCCAGGGCAACCGAGTGCTCGTTGTCCATGATGGTTTCGAGGGCCTGGCCAAGGGGCAGATAAGGAAGCCATTAAGGTCAC
TCCACTGCCATGTATGCAACTGCTGTGTGGCTCGATATGATCAACACTGCCTGTGGACTGGACGGTGCATAGGTTTTGGCAACCATCACT
ATTACATATTCTTCTTGTTTTTCCTTTCCATGGTATGTGGCTGGATTATATATGGATCTTTCATCTATTTGTCCAGTCATTGTGCCACAA
CATTCAAAGAAGATGGATTATGGACTTACCTCAATCAGATTGTGGCCTGTTCCCCTTGGGTTTTATATATCTTGATGCTAGCAACTTTCC
ATTTCTCATGGTCAACATTTTTATTATTAAATCAACTCTTTCAGATTGCCTTTCTGGGCCTGACCTCCCATGAGAGAATCAGCCTGCAGA
AGCAGAGCAAGCATATGAAACAGACGTTGTCCCTCAGGAAGACACCATACAATCTTGGATTCATGCAGAACCTGGCAGATTTCTTTCAGT
GTGGCTGCTTTGGCTTGGTGAAGCCCTGTGTGGTAGATTGGACATCACAGTACACCATGGTCTTTCACCCAGCCAGGGAGAAGGTTCTTC
GCTCAGTATGAAGAAAAGCAACCCAAAACTCTCAATCTGATTTGTTTTTGTTTATGTCGATGCCCTGTAGTTTGAAAGTGAAGTAAAGAT
TTAGAATTCACCTAAGTCCAAAGGAAAACACGTGGTTTTTAAAGCCATTAGGTAAAAAAAGTTCTCAATAAAGGCATTACAATTTTTTAG
GTTTAGAAAGATGGACTTTTCTGATAAATCTTGGCAGACATCTAAAAAAAAAACCATATTTTTCACAAGAAAATGCAAGTTACTTTTTTT
GGAAATAATACTCACTGATTATGGATAAAATGGAATATTTTCAGATACTATATTGGCTGTTTCAAAATAGTACTATTCTTTAAACTTGTA
ATTTTTGCTAAGTTATTTGTCTTTGTTGTATCTATAAATATGTAAAAAATATTTAAATAGATGTACCTGTTTTGCTTTCACACTTAATAA

>64457_64457_4_PFKM-ZDHHC13_PFKM_chr12_48534654_ENST00000340802_ZDHHC13_chr11_19186598_ENST00000446113_length(amino acids)=708AA_BP=518
MHKDEFHLKFFMCVIQSRQLVRTPQRTAGEASTSSMLIPKPPPKTDILKSLDTMDDPDTVGSIPVFKTEWIMTHEEHHAAKTLGIGKAIA
VLTSGGDAQGMNAAVRAVVRVGIFTGARVFFVHEGYQGLVDGGDHIKEATWESVSMMLQLGGTVIGSARCKDFREREGRLRAAYNLVKRG
ITNLCVIGGDGSLTGADTFRSEWSDLLSDLQKAGKITDEEATKSSYLNIVGLVGSIDNDFCGTDMTIGTDSALHRIMEIVDAITTTAQSH
QRTFVLEVMGRHCGYLALVTSLSCGADWVFIPECPPDDDWEEHLCRRLSETRTRGSRLNIIIVAEGAIDKNGKPITSEDIKNLVVKRLGY
DTRVTVLGHVQRGGTPSAFDRILGSRMGVEAVMALLEGTPDTPACVVSLSGNQAVRLPLMECVQVTKDVTKAMDEKKFDEALKLRGRSFM
NNWEVYKLLAHVRPPVSKSGSHTVAVMNVGAPAAGMNAAVRSTVRIGLIQGNRVLVVHDGFEGLAKGQIRKPLRSLHCHVCNCCVARYDQ
HCLWTGRCIGFGNHHYYIFFLFFLSMVCGWIIYGSFIYLSSHCATTFKEDGLWTYLNQIVACSPWVLYILMLATFHFSWSTFLLLNQLFQ

--------------------------------------------------------------
>64457_64457_5_PFKM-ZDHHC13_PFKM_chr12_48534654_ENST00000359794_ZDHHC13_chr11_19186598_ENST00000399351_length(transcript)=2558nt_BP=1530nt
AAGCAGGAGGAGGCGGAGCCTTCTTGTCAGCATCTGTTAGTGGAGGTTGGGAAGCCTCTCCTCCTTCCCCCTCCCTCTTTGCCTCCACCT
GGCTCCTCCCCATGTTCGTCCATCACCCCTCCCCCCTTTCCCAAGGACAATCTGCAAGAAAGCAGCGGCGGAGGAGAGCTAAGACTAAAA
GAGTGGATCATGACCCATGAAGAGCACCATGCAGCCAAAACCCTGGGGATTGGCAAAGCCATTGCTGTCTTAACCTCTGGTGGAGATGCC
CAAGGTATGAATGCTGCTGTCAGGGCTGTGGTTCGAGTTGGTATCTTCACCGGTGCCCGTGTCTTCTTTGTCCATGAGGGTTATCAAGGC
CTGGTGGATGGTGGAGATCACATCAAGGAAGCCACCTGGGAGAGCGTTTCGATGATGCTTCAGCTGGGAGGCACGGTGATTGGAAGTGCC
CGGTGCAAGGACTTTCGGGAACGAGAAGGACGACTCCGAGCTGCCTACAACCTGGTGAAGCGTGGGATCACCAATCTCTGTGTCATTGGG
GGTGATGGCAGCCTCACTGGGGCTGACACCTTCCGTTCTGAGTGGAGTGACTTGTTGAGTGACCTCCAGAAAGCAGGTAAGATCACAGAT
GAGGAGGCTACGAAGTCCAGCTACCTGAACATTGTGGGCCTGGTTGGGTCAATTGACAATGACTTCTGTGGCACCGATATGACCATTGGC
ACTGACTCTGCCCTGCATCGGATCATGGAAATTGTAGATGCCATCACTACCACTGCCCAGAGCCACCAGAGGACATTTGTGTTAGAAGTA
ATGGGCCGCCACTGTGGATACCTGGCCCTTGTCACCTCTCTGTCCTGTGGGGCCGACTGGGTTTTTATTCCTGAATGTCCACCAGATGAC
GACTGGGAGGAACACCTTTGTCGCCGACTCAGCGAGACAAGGACCCGTGGTTCTCGTCTCAACATCATCATTGTGGCTGAGGGTGCAATT
GACAAGAATGGAAAACCAATCACCTCAGAAGACATCAAGAATCTGGTGGTTAAGCGTCTGGGATATGACACCCGGGTTACTGTCTTGGGG
CATGTGCAGAGGGGTGGGACGCCATCAGCCTTTGACAGAATTCTGGGCAGCAGGATGGGTGTGGAAGCAGTGATGGCACTTTTGGAGGGG
ACCCCAGATACCCCAGCCTGTGTAGTGAGCCTCTCTGGTAACCAGGCTGTGCGCCTGCCCCTCATGGAATGTGTCCAGGTGACCAAAGAT
GTGACCAAGGCCATGGATGAGAAGAAATTTGACGAAGCCCTGAAGCTGAGAGGCCGGAGCTTCATGAACAACTGGGAGGTGTACAAGCTT
CTAGCTCATGTCAGACCCCCGGTATCTAAGAGTGGTTCGCACACAGTGGCTGTGATGAACGTGGGGGCTCCGGCTGCAGGCATGAATGCT
GCTGTTCGCTCCACTGTGAGGATTGGCCTTATCCAGGGCAACCGAGTGCTCGTTGTCCATGATGGTTTCGAGGGCCTGGCCAAGGGGCAG
ATAAGGAAGCCATTAAGGTCACTCCACTGCCATGTATGCAACTGCTGTGTGGCTCGATATGATCAACACTGCCTGTGGACTGGACGGTGC
ATAGGTTTTGGCAACCATCACTATTACATATTCTTCTTGTTTTTCCTTTCCATGGTATGTGGCTGGATTATATATGGATCTTTCATCTAT
TTGTCCAGTCATTGTGCCACAACATTCAAAGAAGATGGATTATGGACTTACCTCAATCAGATTGTGGCCTGTTCCCCTTGGGTTTTATAT
ATCTTGATGCTAGCAACTTTCCATTTCTCATGGTCAACATTTTTATTATTAAATCAACTCTTTCAGATTGCCTTTCTGGGCCTGACCTCC
CATGAGAGAATCAGCCTGCAGAAGCAGAGCAAGCATATGAAACAGACGTTGTCCCTCAGGAAGACACCATACAATCTTGGATTCATGCAG
AACCTGGCAGATTTCTTTCAGTGTGGCTGCTTTGGCTTGGTGAAGCCCTGTGTGGTAGATTGGACATCACAGTACACCATGGTCTTTCAC
CCAGCCAGGGAGAAGGTTCTTCGCTCAGTATGAAGAAAAGCAACCCAAAACTCTCAATCTGATTTGTTTTTGTTTATGTCGATGCCCTGT
AGTTTGAAAGTGAAGTAAAGATTTAGAATTCACCTAAGTCCAAAGGAAAACACGTGGTTTTTAAAGCCATTAGGTAAAAAAAGTTCTCAA
TAAAGGCATTACAATTTTTTAGGTTTAGAAAGATGGACTTTTCTGATAAATCTTGGCAGACATCTAAAAAAAAAACCATATTTTTCACAA
GAAAATGCAAGTTACTTTTTTTGGAAATAATACTCACTGATTATGGATAAAATGGAATATTTTCAGATACTATATTGGCTGTTTCAAAAT
AGTACTATTCTTTAAACTTGTAATTTTTGCTAAGTTATTTGTCTTTGTTGTATCTATAAATATGTAAAAAATATTTAAATAGATGTACCT

>64457_64457_5_PFKM-ZDHHC13_PFKM_chr12_48534654_ENST00000359794_ZDHHC13_chr11_19186598_ENST00000399351_length(amino acids)=689AA_BP=499
MLVEVGKPLLLPPPSLPPPGSSPCSSITPPPFPKDNLQESSGGGELRLKEWIMTHEEHHAAKTLGIGKAIAVLTSGGDAQGMNAAVRAVV
RVGIFTGARVFFVHEGYQGLVDGGDHIKEATWESVSMMLQLGGTVIGSARCKDFREREGRLRAAYNLVKRGITNLCVIGGDGSLTGADTF
RSEWSDLLSDLQKAGKITDEEATKSSYLNIVGLVGSIDNDFCGTDMTIGTDSALHRIMEIVDAITTTAQSHQRTFVLEVMGRHCGYLALV
TSLSCGADWVFIPECPPDDDWEEHLCRRLSETRTRGSRLNIIIVAEGAIDKNGKPITSEDIKNLVVKRLGYDTRVTVLGHVQRGGTPSAF
DRILGSRMGVEAVMALLEGTPDTPACVVSLSGNQAVRLPLMECVQVTKDVTKAMDEKKFDEALKLRGRSFMNNWEVYKLLAHVRPPVSKS
GSHTVAVMNVGAPAAGMNAAVRSTVRIGLIQGNRVLVVHDGFEGLAKGQIRKPLRSLHCHVCNCCVARYDQHCLWTGRCIGFGNHHYYIF
FLFFLSMVCGWIIYGSFIYLSSHCATTFKEDGLWTYLNQIVACSPWVLYILMLATFHFSWSTFLLLNQLFQIAFLGLTSHERISLQKQSK

--------------------------------------------------------------
>64457_64457_6_PFKM-ZDHHC13_PFKM_chr12_48534654_ENST00000359794_ZDHHC13_chr11_19186598_ENST00000446113_length(transcript)=2558nt_BP=1530nt
AAGCAGGAGGAGGCGGAGCCTTCTTGTCAGCATCTGTTAGTGGAGGTTGGGAAGCCTCTCCTCCTTCCCCCTCCCTCTTTGCCTCCACCT
GGCTCCTCCCCATGTTCGTCCATCACCCCTCCCCCCTTTCCCAAGGACAATCTGCAAGAAAGCAGCGGCGGAGGAGAGCTAAGACTAAAA
GAGTGGATCATGACCCATGAAGAGCACCATGCAGCCAAAACCCTGGGGATTGGCAAAGCCATTGCTGTCTTAACCTCTGGTGGAGATGCC
CAAGGTATGAATGCTGCTGTCAGGGCTGTGGTTCGAGTTGGTATCTTCACCGGTGCCCGTGTCTTCTTTGTCCATGAGGGTTATCAAGGC
CTGGTGGATGGTGGAGATCACATCAAGGAAGCCACCTGGGAGAGCGTTTCGATGATGCTTCAGCTGGGAGGCACGGTGATTGGAAGTGCC
CGGTGCAAGGACTTTCGGGAACGAGAAGGACGACTCCGAGCTGCCTACAACCTGGTGAAGCGTGGGATCACCAATCTCTGTGTCATTGGG
GGTGATGGCAGCCTCACTGGGGCTGACACCTTCCGTTCTGAGTGGAGTGACTTGTTGAGTGACCTCCAGAAAGCAGGTAAGATCACAGAT
GAGGAGGCTACGAAGTCCAGCTACCTGAACATTGTGGGCCTGGTTGGGTCAATTGACAATGACTTCTGTGGCACCGATATGACCATTGGC
ACTGACTCTGCCCTGCATCGGATCATGGAAATTGTAGATGCCATCACTACCACTGCCCAGAGCCACCAGAGGACATTTGTGTTAGAAGTA
ATGGGCCGCCACTGTGGATACCTGGCCCTTGTCACCTCTCTGTCCTGTGGGGCCGACTGGGTTTTTATTCCTGAATGTCCACCAGATGAC
GACTGGGAGGAACACCTTTGTCGCCGACTCAGCGAGACAAGGACCCGTGGTTCTCGTCTCAACATCATCATTGTGGCTGAGGGTGCAATT
GACAAGAATGGAAAACCAATCACCTCAGAAGACATCAAGAATCTGGTGGTTAAGCGTCTGGGATATGACACCCGGGTTACTGTCTTGGGG
CATGTGCAGAGGGGTGGGACGCCATCAGCCTTTGACAGAATTCTGGGCAGCAGGATGGGTGTGGAAGCAGTGATGGCACTTTTGGAGGGG
ACCCCAGATACCCCAGCCTGTGTAGTGAGCCTCTCTGGTAACCAGGCTGTGCGCCTGCCCCTCATGGAATGTGTCCAGGTGACCAAAGAT
GTGACCAAGGCCATGGATGAGAAGAAATTTGACGAAGCCCTGAAGCTGAGAGGCCGGAGCTTCATGAACAACTGGGAGGTGTACAAGCTT
CTAGCTCATGTCAGACCCCCGGTATCTAAGAGTGGTTCGCACACAGTGGCTGTGATGAACGTGGGGGCTCCGGCTGCAGGCATGAATGCT
GCTGTTCGCTCCACTGTGAGGATTGGCCTTATCCAGGGCAACCGAGTGCTCGTTGTCCATGATGGTTTCGAGGGCCTGGCCAAGGGGCAG
ATAAGGAAGCCATTAAGGTCACTCCACTGCCATGTATGCAACTGCTGTGTGGCTCGATATGATCAACACTGCCTGTGGACTGGACGGTGC
ATAGGTTTTGGCAACCATCACTATTACATATTCTTCTTGTTTTTCCTTTCCATGGTATGTGGCTGGATTATATATGGATCTTTCATCTAT
TTGTCCAGTCATTGTGCCACAACATTCAAAGAAGATGGATTATGGACTTACCTCAATCAGATTGTGGCCTGTTCCCCTTGGGTTTTATAT
ATCTTGATGCTAGCAACTTTCCATTTCTCATGGTCAACATTTTTATTATTAAATCAACTCTTTCAGATTGCCTTTCTGGGCCTGACCTCC
CATGAGAGAATCAGCCTGCAGAAGCAGAGCAAGCATATGAAACAGACGTTGTCCCTCAGGAAGACACCATACAATCTTGGATTCATGCAG
AACCTGGCAGATTTCTTTCAGTGTGGCTGCTTTGGCTTGGTGAAGCCCTGTGTGGTAGATTGGACATCACAGTACACCATGGTCTTTCAC
CCAGCCAGGGAGAAGGTTCTTCGCTCAGTATGAAGAAAAGCAACCCAAAACTCTCAATCTGATTTGTTTTTGTTTATGTCGATGCCCTGT
AGTTTGAAAGTGAAGTAAAGATTTAGAATTCACCTAAGTCCAAAGGAAAACACGTGGTTTTTAAAGCCATTAGGTAAAAAAAGTTCTCAA
TAAAGGCATTACAATTTTTTAGGTTTAGAAAGATGGACTTTTCTGATAAATCTTGGCAGACATCTAAAAAAAAAACCATATTTTTCACAA
GAAAATGCAAGTTACTTTTTTTGGAAATAATACTCACTGATTATGGATAAAATGGAATATTTTCAGATACTATATTGGCTGTTTCAAAAT
AGTACTATTCTTTAAACTTGTAATTTTTGCTAAGTTATTTGTCTTTGTTGTATCTATAAATATGTAAAAAATATTTAAATAGATGTACCT

>64457_64457_6_PFKM-ZDHHC13_PFKM_chr12_48534654_ENST00000359794_ZDHHC13_chr11_19186598_ENST00000446113_length(amino acids)=689AA_BP=499
MLVEVGKPLLLPPPSLPPPGSSPCSSITPPPFPKDNLQESSGGGELRLKEWIMTHEEHHAAKTLGIGKAIAVLTSGGDAQGMNAAVRAVV
RVGIFTGARVFFVHEGYQGLVDGGDHIKEATWESVSMMLQLGGTVIGSARCKDFREREGRLRAAYNLVKRGITNLCVIGGDGSLTGADTF
RSEWSDLLSDLQKAGKITDEEATKSSYLNIVGLVGSIDNDFCGTDMTIGTDSALHRIMEIVDAITTTAQSHQRTFVLEVMGRHCGYLALV
TSLSCGADWVFIPECPPDDDWEEHLCRRLSETRTRGSRLNIIIVAEGAIDKNGKPITSEDIKNLVVKRLGYDTRVTVLGHVQRGGTPSAF
DRILGSRMGVEAVMALLEGTPDTPACVVSLSGNQAVRLPLMECVQVTKDVTKAMDEKKFDEALKLRGRSFMNNWEVYKLLAHVRPPVSKS
GSHTVAVMNVGAPAAGMNAAVRSTVRIGLIQGNRVLVVHDGFEGLAKGQIRKPLRSLHCHVCNCCVARYDQHCLWTGRCIGFGNHHYYIF
FLFFLSMVCGWIIYGSFIYLSSHCATTFKEDGLWTYLNQIVACSPWVLYILMLATFHFSWSTFLLLNQLFQIAFLGLTSHERISLQKQSK

--------------------------------------------------------------
>64457_64457_7_PFKM-ZDHHC13_PFKM_chr12_48534654_ENST00000395233_ZDHHC13_chr11_19186598_ENST00000399351_length(transcript)=2313nt_BP=1285nt
CAGCGGCGGAGGAGAGCTAAGACTAAAAGAGTGGATCATGACCCATGAAGAGCACCATGCAGCCAAAACCCTGGGGATTGGCAAAGCCAT
TGCTGTCTTAACCTCTGGTGGAGATGCCCAAGGTATGAATGCTGCTGTCAGGGCTGTGGTTCGAGTTGGTATCTTCACCGGTGCCCGTGT
CTTCTTTGTCCATGAGGGTTATCAAGGCCTGGTGGATGGTGGAGATCACATCAAGGAAGCCACCTGGGAGAGCGTTTCGATGATGCTTCA
GCTGGGAGGCACGGTGATTGGAAGTGCCCGGTGCAAGGACTTTCGGGAACGAGAAGGACGACTCCGAGCTGCCTACAACCTGGTGAAGCG
TGGGATCACCAATCTCTGTGTCATTGGGGGTGATGGCAGCCTCACTGGGGCTGACACCTTCCGTTCTGAGTGGAGTGACTTGTTGAGTGA
CCTCCAGAAAGCAGGTAAGATCACAGATGAGGAGGCTACGAAGTCCAGCTACCTGAACATTGTGGGCCTGGTTGGGTCAATTGACAATGA
CTTCTGTGGCACCGATATGACCATTGGCACTGACTCTGCCCTGCATCGGATCATGGAAATTGTAGATGCCATCACTACCACTGCCCAGAG
CCACCAGAGGACATTTGTGTTAGAAGTAATGGGCCGCCACTGTGGATACCTGGCCCTTGTCACCTCTCTGTCCTGTGGGGCCGACTGGGT
TTTTATTCCTGAATGTCCACCAGATGACGACTGGGAGGAACACCTTTGTCGCCGACTCAGCGAGACAAGGACCCGTGGTTCTCGTCTCAA
CATCATCATTGTGGCTGAGGGTGCAATTGACAAGAATGGAAAACCAATCACCTCAGAAGACATCAAGAATGGCAGCAGGATGGGTGTGGA
AGCAGTGATGGCACTTTTGGAGGGGACCCCAGATACCCCAGCCTGTGTAGTGAGCCTCTCTGGTAACCAGGCTGTGCGCCTGCCCCTCAT
GGAATGTGTCCAGGTGACCAAAGATGTGACCAAGGCCATGGATGAGAAGAAATTTGACGAAGCCCTGAAGCTGAGAGGCCGGAGCTTCAT
GAACAACTGGGAGGTGTACAAGCTTCTAGCTCATGTCAGACCCCCGGTATCTAAGAGTGGTTCGCACACAGTGGCTGTGATGAACGTGGG
GGCTCCGGCTGCAGGCATGAATGCTGCTGTTCGCTCCACTGTGAGGATTGGCCTTATCCAGGGCAACCGAGTGCTCGTTGTCCATGATGG
TTTCGAGGGCCTGGCCAAGGGGCAGATAAGGAAGCCATTAAGGTCACTCCACTGCCATGTATGCAACTGCTGTGTGGCTCGATATGATCA
ACACTGCCTGTGGACTGGACGGTGCATAGGTTTTGGCAACCATCACTATTACATATTCTTCTTGTTTTTCCTTTCCATGGTATGTGGCTG
GATTATATATGGATCTTTCATCTATTTGTCCAGTCATTGTGCCACAACATTCAAAGAAGATGGATTATGGACTTACCTCAATCAGATTGT
GGCCTGTTCCCCTTGGGTTTTATATATCTTGATGCTAGCAACTTTCCATTTCTCATGGTCAACATTTTTATTATTAAATCAACTCTTTCA
GATTGCCTTTCTGGGCCTGACCTCCCATGAGAGAATCAGCCTGCAGAAGCAGAGCAAGCATATGAAACAGACGTTGTCCCTCAGGAAGAC
ACCATACAATCTTGGATTCATGCAGAACCTGGCAGATTTCTTTCAGTGTGGCTGCTTTGGCTTGGTGAAGCCCTGTGTGGTAGATTGGAC
ATCACAGTACACCATGGTCTTTCACCCAGCCAGGGAGAAGGTTCTTCGCTCAGTATGAAGAAAAGCAACCCAAAACTCTCAATCTGATTT
GTTTTTGTTTATGTCGATGCCCTGTAGTTTGAAAGTGAAGTAAAGATTTAGAATTCACCTAAGTCCAAAGGAAAACACGTGGTTTTTAAA
GCCATTAGGTAAAAAAAGTTCTCAATAAAGGCATTACAATTTTTTAGGTTTAGAAAGATGGACTTTTCTGATAAATCTTGGCAGACATCT
AAAAAAAAAACCATATTTTTCACAAGAAAATGCAAGTTACTTTTTTTGGAAATAATACTCACTGATTATGGATAAAATGGAATATTTTCA
GATACTATATTGGCTGTTTCAAAATAGTACTATTCTTTAAACTTGTAATTTTTGCTAAGTTATTTGTCTTTGTTGTATCTATAAATATGT

>64457_64457_7_PFKM-ZDHHC13_PFKM_chr12_48534654_ENST00000395233_ZDHHC13_chr11_19186598_ENST00000399351_length(amino acids)=606AA_BP=416
MTHEEHHAAKTLGIGKAIAVLTSGGDAQGMNAAVRAVVRVGIFTGARVFFVHEGYQGLVDGGDHIKEATWESVSMMLQLGGTVIGSARCK
DFREREGRLRAAYNLVKRGITNLCVIGGDGSLTGADTFRSEWSDLLSDLQKAGKITDEEATKSSYLNIVGLVGSIDNDFCGTDMTIGTDS
ALHRIMEIVDAITTTAQSHQRTFVLEVMGRHCGYLALVTSLSCGADWVFIPECPPDDDWEEHLCRRLSETRTRGSRLNIIIVAEGAIDKN
GKPITSEDIKNGSRMGVEAVMALLEGTPDTPACVVSLSGNQAVRLPLMECVQVTKDVTKAMDEKKFDEALKLRGRSFMNNWEVYKLLAHV
RPPVSKSGSHTVAVMNVGAPAAGMNAAVRSTVRIGLIQGNRVLVVHDGFEGLAKGQIRKPLRSLHCHVCNCCVARYDQHCLWTGRCIGFG
NHHYYIFFLFFLSMVCGWIIYGSFIYLSSHCATTFKEDGLWTYLNQIVACSPWVLYILMLATFHFSWSTFLLLNQLFQIAFLGLTSHERI

--------------------------------------------------------------
>64457_64457_8_PFKM-ZDHHC13_PFKM_chr12_48534654_ENST00000395233_ZDHHC13_chr11_19186598_ENST00000446113_length(transcript)=2313nt_BP=1285nt
CAGCGGCGGAGGAGAGCTAAGACTAAAAGAGTGGATCATGACCCATGAAGAGCACCATGCAGCCAAAACCCTGGGGATTGGCAAAGCCAT
TGCTGTCTTAACCTCTGGTGGAGATGCCCAAGGTATGAATGCTGCTGTCAGGGCTGTGGTTCGAGTTGGTATCTTCACCGGTGCCCGTGT
CTTCTTTGTCCATGAGGGTTATCAAGGCCTGGTGGATGGTGGAGATCACATCAAGGAAGCCACCTGGGAGAGCGTTTCGATGATGCTTCA
GCTGGGAGGCACGGTGATTGGAAGTGCCCGGTGCAAGGACTTTCGGGAACGAGAAGGACGACTCCGAGCTGCCTACAACCTGGTGAAGCG
TGGGATCACCAATCTCTGTGTCATTGGGGGTGATGGCAGCCTCACTGGGGCTGACACCTTCCGTTCTGAGTGGAGTGACTTGTTGAGTGA
CCTCCAGAAAGCAGGTAAGATCACAGATGAGGAGGCTACGAAGTCCAGCTACCTGAACATTGTGGGCCTGGTTGGGTCAATTGACAATGA
CTTCTGTGGCACCGATATGACCATTGGCACTGACTCTGCCCTGCATCGGATCATGGAAATTGTAGATGCCATCACTACCACTGCCCAGAG
CCACCAGAGGACATTTGTGTTAGAAGTAATGGGCCGCCACTGTGGATACCTGGCCCTTGTCACCTCTCTGTCCTGTGGGGCCGACTGGGT
TTTTATTCCTGAATGTCCACCAGATGACGACTGGGAGGAACACCTTTGTCGCCGACTCAGCGAGACAAGGACCCGTGGTTCTCGTCTCAA
CATCATCATTGTGGCTGAGGGTGCAATTGACAAGAATGGAAAACCAATCACCTCAGAAGACATCAAGAATGGCAGCAGGATGGGTGTGGA
AGCAGTGATGGCACTTTTGGAGGGGACCCCAGATACCCCAGCCTGTGTAGTGAGCCTCTCTGGTAACCAGGCTGTGCGCCTGCCCCTCAT
GGAATGTGTCCAGGTGACCAAAGATGTGACCAAGGCCATGGATGAGAAGAAATTTGACGAAGCCCTGAAGCTGAGAGGCCGGAGCTTCAT
GAACAACTGGGAGGTGTACAAGCTTCTAGCTCATGTCAGACCCCCGGTATCTAAGAGTGGTTCGCACACAGTGGCTGTGATGAACGTGGG
GGCTCCGGCTGCAGGCATGAATGCTGCTGTTCGCTCCACTGTGAGGATTGGCCTTATCCAGGGCAACCGAGTGCTCGTTGTCCATGATGG
TTTCGAGGGCCTGGCCAAGGGGCAGATAAGGAAGCCATTAAGGTCACTCCACTGCCATGTATGCAACTGCTGTGTGGCTCGATATGATCA
ACACTGCCTGTGGACTGGACGGTGCATAGGTTTTGGCAACCATCACTATTACATATTCTTCTTGTTTTTCCTTTCCATGGTATGTGGCTG
GATTATATATGGATCTTTCATCTATTTGTCCAGTCATTGTGCCACAACATTCAAAGAAGATGGATTATGGACTTACCTCAATCAGATTGT
GGCCTGTTCCCCTTGGGTTTTATATATCTTGATGCTAGCAACTTTCCATTTCTCATGGTCAACATTTTTATTATTAAATCAACTCTTTCA
GATTGCCTTTCTGGGCCTGACCTCCCATGAGAGAATCAGCCTGCAGAAGCAGAGCAAGCATATGAAACAGACGTTGTCCCTCAGGAAGAC
ACCATACAATCTTGGATTCATGCAGAACCTGGCAGATTTCTTTCAGTGTGGCTGCTTTGGCTTGGTGAAGCCCTGTGTGGTAGATTGGAC
ATCACAGTACACCATGGTCTTTCACCCAGCCAGGGAGAAGGTTCTTCGCTCAGTATGAAGAAAAGCAACCCAAAACTCTCAATCTGATTT
GTTTTTGTTTATGTCGATGCCCTGTAGTTTGAAAGTGAAGTAAAGATTTAGAATTCACCTAAGTCCAAAGGAAAACACGTGGTTTTTAAA
GCCATTAGGTAAAAAAAGTTCTCAATAAAGGCATTACAATTTTTTAGGTTTAGAAAGATGGACTTTTCTGATAAATCTTGGCAGACATCT
AAAAAAAAAACCATATTTTTCACAAGAAAATGCAAGTTACTTTTTTTGGAAATAATACTCACTGATTATGGATAAAATGGAATATTTTCA
GATACTATATTGGCTGTTTCAAAATAGTACTATTCTTTAAACTTGTAATTTTTGCTAAGTTATTTGTCTTTGTTGTATCTATAAATATGT

>64457_64457_8_PFKM-ZDHHC13_PFKM_chr12_48534654_ENST00000395233_ZDHHC13_chr11_19186598_ENST00000446113_length(amino acids)=606AA_BP=416
MTHEEHHAAKTLGIGKAIAVLTSGGDAQGMNAAVRAVVRVGIFTGARVFFVHEGYQGLVDGGDHIKEATWESVSMMLQLGGTVIGSARCK
DFREREGRLRAAYNLVKRGITNLCVIGGDGSLTGADTFRSEWSDLLSDLQKAGKITDEEATKSSYLNIVGLVGSIDNDFCGTDMTIGTDS
ALHRIMEIVDAITTTAQSHQRTFVLEVMGRHCGYLALVTSLSCGADWVFIPECPPDDDWEEHLCRRLSETRTRGSRLNIIIVAEGAIDKN
GKPITSEDIKNGSRMGVEAVMALLEGTPDTPACVVSLSGNQAVRLPLMECVQVTKDVTKAMDEKKFDEALKLRGRSFMNNWEVYKLLAHV
RPPVSKSGSHTVAVMNVGAPAAGMNAAVRSTVRIGLIQGNRVLVVHDGFEGLAKGQIRKPLRSLHCHVCNCCVARYDQHCLWTGRCIGFG
NHHYYIFFLFFLSMVCGWIIYGSFIYLSSHCATTFKEDGLWTYLNQIVACSPWVLYILMLATFHFSWSTFLLLNQLFQIAFLGLTSHERI

--------------------------------------------------------------
>64457_64457_9_PFKM-ZDHHC13_PFKM_chr12_48534654_ENST00000547587_ZDHHC13_chr11_19186598_ENST00000399351_length(transcript)=2497nt_BP=1469nt
AGACTTGGTATAGTGGGAGAGCCTGACTGAGGTGGCTCTAGCCAGTCTAATTGCCGTTCCTTTAGCTAGTGGCATCTTGATTCCTGCTGT
GTCTTAACTGACCATTGTCTTAAATTCTAGAGTGGATCATGACCCATGAAGAGCACCATGCAGCCAAAACCCTGGGGATTGGCAAAGCCA
TTGCTGTCTTAACCTCTGGTGGAGATGCCCAAGGTATGAATGCTGCTGTCAGGGCTGTGGTTCGAGTTGGTATCTTCACCGGTGCCCGTG
TCTTCTTTGTCCATGAGGGTTATCAAGGCCTGGTGGATGGTGGAGATCACATCAAGGAAGCCACCTGGGAGAGCGTTTCGATGATGCTTC
AGCTGGGAGGCACGGTGATTGGAAGTGCCCGGTGCAAGGACTTTCGGGAACGAGAAGGACGACTCCGAGCTGCCTACAACCTGGTGAAGC
GTGGGATCACCAATCTCTGTGTCATTGGGGGTGATGGCAGCCTCACTGGGGCTGACACCTTCCGTTCTGAGTGGAGTGACTTGTTGAGTG
ACCTCCAGAAAGCAGGTAAGATCACAGATGAGGAGGCTACGAAGTCCAGCTACCTGAACATTGTGGGCCTGGTTGGGTCAATTGACAATG
ACTTCTGTGGCACCGATATGACCATTGGCACTGACTCTGCCCTGCATCGGATCATGGAAATTGTAGATGCCATCACTACCACTGCCCAGA
GCCACCAGAGGACATTTGTGTTAGAAGTAATGGGCCGCCACTGTGGATACCTGGCCCTTGTCACCTCTCTGTCCTGTGGGGCCGACTGGG
TTTTTATTCCTGAATGTCCACCAGATGACGACTGGGAGGAACACCTTTGTCGCCGACTCAGCGAGACAAGGACCCGTGGTTCTCGTCTCA
ACATCATCATTGTGGCTGAGGGTGCAATTGACAAGAATGGAAAACCAATCACCTCAGAAGACATCAAGAATCTGGTGGTTAAGCGTCTGG
GATATGACACCCGGGTTACTGTCTTGGGGCATGTGCAGAGGGGTGGGACGCCATCAGCCTTTGACAGAATTCTGGGCAGCAGGATGGGTG
TGGAAGCAGTGATGGCACTTTTGGAGGGGACCCCAGATACCCCAGCCTGTGTAGTGAGCCTCTCTGGTAACCAGGCTGTGCGCCTGCCCC
TCATGGAATGTGTCCAGGTGACCAAAGATGTGACCAAGGCCATGGATGAGAAGAAATTTGACGAAGCCCTGAAGCTGAGAGGCCGGAGCT
TCATGAACAACTGGGAGGTGTACAAGCTTCTAGCTCATGTCAGACCCCCGGTATCTAAGAGTGGTTCGCACACAGTGGCTGTGATGAACG
TGGGGGCTCCGGCTGCAGGCATGAATGCTGCTGTTCGCTCCACTGTGAGGATTGGCCTTATCCAGGGCAACCGAGTGCTCGTTGTCCATG
ATGGTTTCGAGGGCCTGGCCAAGGGGCAGATAAGGAAGCCATTAAGGTCACTCCACTGCCATGTATGCAACTGCTGTGTGGCTCGATATG
ATCAACACTGCCTGTGGACTGGACGGTGCATAGGTTTTGGCAACCATCACTATTACATATTCTTCTTGTTTTTCCTTTCCATGGTATGTG
GCTGGATTATATATGGATCTTTCATCTATTTGTCCAGTCATTGTGCCACAACATTCAAAGAAGATGGATTATGGACTTACCTCAATCAGA
TTGTGGCCTGTTCCCCTTGGGTTTTATATATCTTGATGCTAGCAACTTTCCATTTCTCATGGTCAACATTTTTATTATTAAATCAACTCT
TTCAGATTGCCTTTCTGGGCCTGACCTCCCATGAGAGAATCAGCCTGCAGAAGCAGAGCAAGCATATGAAACAGACGTTGTCCCTCAGGA
AGACACCATACAATCTTGGATTCATGCAGAACCTGGCAGATTTCTTTCAGTGTGGCTGCTTTGGCTTGGTGAAGCCCTGTGTGGTAGATT
GGACATCACAGTACACCATGGTCTTTCACCCAGCCAGGGAGAAGGTTCTTCGCTCAGTATGAAGAAAAGCAACCCAAAACTCTCAATCTG
ATTTGTTTTTGTTTATGTCGATGCCCTGTAGTTTGAAAGTGAAGTAAAGATTTAGAATTCACCTAAGTCCAAAGGAAAACACGTGGTTTT
TAAAGCCATTAGGTAAAAAAAGTTCTCAATAAAGGCATTACAATTTTTTAGGTTTAGAAAGATGGACTTTTCTGATAAATCTTGGCAGAC
ATCTAAAAAAAAAACCATATTTTTCACAAGAAAATGCAAGTTACTTTTTTTGGAAATAATACTCACTGATTATGGATAAAATGGAATATT
TTCAGATACTATATTGGCTGTTTCAAAATAGTACTATTCTTTAAACTTGTAATTTTTGCTAAGTTATTTGTCTTTGTTGTATCTATAAAT

>64457_64457_9_PFKM-ZDHHC13_PFKM_chr12_48534654_ENST00000547587_ZDHHC13_chr11_19186598_ENST00000399351_length(amino acids)=637AA_BP=447
MTHEEHHAAKTLGIGKAIAVLTSGGDAQGMNAAVRAVVRVGIFTGARVFFVHEGYQGLVDGGDHIKEATWESVSMMLQLGGTVIGSARCK
DFREREGRLRAAYNLVKRGITNLCVIGGDGSLTGADTFRSEWSDLLSDLQKAGKITDEEATKSSYLNIVGLVGSIDNDFCGTDMTIGTDS
ALHRIMEIVDAITTTAQSHQRTFVLEVMGRHCGYLALVTSLSCGADWVFIPECPPDDDWEEHLCRRLSETRTRGSRLNIIIVAEGAIDKN
GKPITSEDIKNLVVKRLGYDTRVTVLGHVQRGGTPSAFDRILGSRMGVEAVMALLEGTPDTPACVVSLSGNQAVRLPLMECVQVTKDVTK
AMDEKKFDEALKLRGRSFMNNWEVYKLLAHVRPPVSKSGSHTVAVMNVGAPAAGMNAAVRSTVRIGLIQGNRVLVVHDGFEGLAKGQIRK
PLRSLHCHVCNCCVARYDQHCLWTGRCIGFGNHHYYIFFLFFLSMVCGWIIYGSFIYLSSHCATTFKEDGLWTYLNQIVACSPWVLYILM
LATFHFSWSTFLLLNQLFQIAFLGLTSHERISLQKQSKHMKQTLSLRKTPYNLGFMQNLADFFQCGCFGLVKPCVVDWTSQYTMVFHPAR

--------------------------------------------------------------
>64457_64457_10_PFKM-ZDHHC13_PFKM_chr12_48534654_ENST00000547587_ZDHHC13_chr11_19186598_ENST00000446113_length(transcript)=2497nt_BP=1469nt
AGACTTGGTATAGTGGGAGAGCCTGACTGAGGTGGCTCTAGCCAGTCTAATTGCCGTTCCTTTAGCTAGTGGCATCTTGATTCCTGCTGT
GTCTTAACTGACCATTGTCTTAAATTCTAGAGTGGATCATGACCCATGAAGAGCACCATGCAGCCAAAACCCTGGGGATTGGCAAAGCCA
TTGCTGTCTTAACCTCTGGTGGAGATGCCCAAGGTATGAATGCTGCTGTCAGGGCTGTGGTTCGAGTTGGTATCTTCACCGGTGCCCGTG
TCTTCTTTGTCCATGAGGGTTATCAAGGCCTGGTGGATGGTGGAGATCACATCAAGGAAGCCACCTGGGAGAGCGTTTCGATGATGCTTC
AGCTGGGAGGCACGGTGATTGGAAGTGCCCGGTGCAAGGACTTTCGGGAACGAGAAGGACGACTCCGAGCTGCCTACAACCTGGTGAAGC
GTGGGATCACCAATCTCTGTGTCATTGGGGGTGATGGCAGCCTCACTGGGGCTGACACCTTCCGTTCTGAGTGGAGTGACTTGTTGAGTG
ACCTCCAGAAAGCAGGTAAGATCACAGATGAGGAGGCTACGAAGTCCAGCTACCTGAACATTGTGGGCCTGGTTGGGTCAATTGACAATG
ACTTCTGTGGCACCGATATGACCATTGGCACTGACTCTGCCCTGCATCGGATCATGGAAATTGTAGATGCCATCACTACCACTGCCCAGA
GCCACCAGAGGACATTTGTGTTAGAAGTAATGGGCCGCCACTGTGGATACCTGGCCCTTGTCACCTCTCTGTCCTGTGGGGCCGACTGGG
TTTTTATTCCTGAATGTCCACCAGATGACGACTGGGAGGAACACCTTTGTCGCCGACTCAGCGAGACAAGGACCCGTGGTTCTCGTCTCA
ACATCATCATTGTGGCTGAGGGTGCAATTGACAAGAATGGAAAACCAATCACCTCAGAAGACATCAAGAATCTGGTGGTTAAGCGTCTGG
GATATGACACCCGGGTTACTGTCTTGGGGCATGTGCAGAGGGGTGGGACGCCATCAGCCTTTGACAGAATTCTGGGCAGCAGGATGGGTG
TGGAAGCAGTGATGGCACTTTTGGAGGGGACCCCAGATACCCCAGCCTGTGTAGTGAGCCTCTCTGGTAACCAGGCTGTGCGCCTGCCCC
TCATGGAATGTGTCCAGGTGACCAAAGATGTGACCAAGGCCATGGATGAGAAGAAATTTGACGAAGCCCTGAAGCTGAGAGGCCGGAGCT
TCATGAACAACTGGGAGGTGTACAAGCTTCTAGCTCATGTCAGACCCCCGGTATCTAAGAGTGGTTCGCACACAGTGGCTGTGATGAACG
TGGGGGCTCCGGCTGCAGGCATGAATGCTGCTGTTCGCTCCACTGTGAGGATTGGCCTTATCCAGGGCAACCGAGTGCTCGTTGTCCATG
ATGGTTTCGAGGGCCTGGCCAAGGGGCAGATAAGGAAGCCATTAAGGTCACTCCACTGCCATGTATGCAACTGCTGTGTGGCTCGATATG
ATCAACACTGCCTGTGGACTGGACGGTGCATAGGTTTTGGCAACCATCACTATTACATATTCTTCTTGTTTTTCCTTTCCATGGTATGTG
GCTGGATTATATATGGATCTTTCATCTATTTGTCCAGTCATTGTGCCACAACATTCAAAGAAGATGGATTATGGACTTACCTCAATCAGA
TTGTGGCCTGTTCCCCTTGGGTTTTATATATCTTGATGCTAGCAACTTTCCATTTCTCATGGTCAACATTTTTATTATTAAATCAACTCT
TTCAGATTGCCTTTCTGGGCCTGACCTCCCATGAGAGAATCAGCCTGCAGAAGCAGAGCAAGCATATGAAACAGACGTTGTCCCTCAGGA
AGACACCATACAATCTTGGATTCATGCAGAACCTGGCAGATTTCTTTCAGTGTGGCTGCTTTGGCTTGGTGAAGCCCTGTGTGGTAGATT
GGACATCACAGTACACCATGGTCTTTCACCCAGCCAGGGAGAAGGTTCTTCGCTCAGTATGAAGAAAAGCAACCCAAAACTCTCAATCTG
ATTTGTTTTTGTTTATGTCGATGCCCTGTAGTTTGAAAGTGAAGTAAAGATTTAGAATTCACCTAAGTCCAAAGGAAAACACGTGGTTTT
TAAAGCCATTAGGTAAAAAAAGTTCTCAATAAAGGCATTACAATTTTTTAGGTTTAGAAAGATGGACTTTTCTGATAAATCTTGGCAGAC
ATCTAAAAAAAAAACCATATTTTTCACAAGAAAATGCAAGTTACTTTTTTTGGAAATAATACTCACTGATTATGGATAAAATGGAATATT
TTCAGATACTATATTGGCTGTTTCAAAATAGTACTATTCTTTAAACTTGTAATTTTTGCTAAGTTATTTGTCTTTGTTGTATCTATAAAT

>64457_64457_10_PFKM-ZDHHC13_PFKM_chr12_48534654_ENST00000547587_ZDHHC13_chr11_19186598_ENST00000446113_length(amino acids)=637AA_BP=447
MTHEEHHAAKTLGIGKAIAVLTSGGDAQGMNAAVRAVVRVGIFTGARVFFVHEGYQGLVDGGDHIKEATWESVSMMLQLGGTVIGSARCK
DFREREGRLRAAYNLVKRGITNLCVIGGDGSLTGADTFRSEWSDLLSDLQKAGKITDEEATKSSYLNIVGLVGSIDNDFCGTDMTIGTDS
ALHRIMEIVDAITTTAQSHQRTFVLEVMGRHCGYLALVTSLSCGADWVFIPECPPDDDWEEHLCRRLSETRTRGSRLNIIIVAEGAIDKN
GKPITSEDIKNLVVKRLGYDTRVTVLGHVQRGGTPSAFDRILGSRMGVEAVMALLEGTPDTPACVVSLSGNQAVRLPLMECVQVTKDVTK
AMDEKKFDEALKLRGRSFMNNWEVYKLLAHVRPPVSKSGSHTVAVMNVGAPAAGMNAAVRSTVRIGLIQGNRVLVVHDGFEGLAKGQIRK
PLRSLHCHVCNCCVARYDQHCLWTGRCIGFGNHHYYIFFLFFLSMVCGWIIYGSFIYLSSHCATTFKEDGLWTYLNQIVACSPWVLYILM
LATFHFSWSTFLLLNQLFQIAFLGLTSHERISLQKQSKHMKQTLSLRKTPYNLGFMQNLADFFQCGCFGLVKPCVVDWTSQYTMVFHPAR

--------------------------------------------------------------
>64457_64457_11_PFKM-ZDHHC13_PFKM_chr12_48534654_ENST00000551804_ZDHHC13_chr11_19186598_ENST00000399351_length(transcript)=2427nt_BP=1399nt
AATATCTGTCTGTTTTTGTCTACGTGCGTGTCATTGTGGGTCTGTAAGGGATGCTTATACATGAGTCTGCATGAATTTCTGTGTCCTGTG
CCTCTATAACTGTCTTAGAGATTTCAGGAGAAGAATATGAGCGGTTTTTACAGAGTGGATCATGACCCATGAAGAGCACCATGCAGCCAA
AACCCTGGGGATTGGCAAAGCCATTGCTGTCTTAACCTCTGGTGGAGATGCCCAAGGTATGAATGCTGCTGTCAGGGCTGTGGTTCGAGT
TGGTATCTTCACCGGTGCCCGTGTCTTCTTTGTCCATGAGGGTTATCAAGGCCTGGTGGATGGTGGAGATCACATCAAGGAAGCCACCTG
GGAGAGCGTTTCGATGATGCTTCAGCTGGGAGGCACGGTGATTGGAAGTGCCCGGTGCAAGGACTTTCGGGAACGAGAAGGACGACTCCG
AGCTGCCTACAACCTGGTGAAGCGTGGGATCACCAATCTCTGTGTCATTGGGGGTGATGGCAGCCTCACTGGGGCTGACACCTTCCGTTC
TGAGTGGAGTGACTTGTTGAGTGACCTCCAGAAAGCAGGTAAGATCACAGATGAGGAGGCTACGAAGTCCAGCTACCTGAACATTGTGGG
CCTGGTTGGGTCAATTGACAATGACTTCTGTGGCACCGATATGACCATTGGCACTGACTCTGCCCTGCATCGGATCATGGAAATTGTAGA
TGCCATCACTACCACTGCCCAGAGCCACCAGAGGACATTTGTGTTAGAAGTAATGGGCCGCCACTGTGGATACCTGGCCCTTGTCACCTC
TCTGTCCTGTGGGGCCGACTGGGTTTTTATTCCTGAATGTCCACCAGATGACGACTGGGAGGAACACCTTTGTCGCCGACTCAGCGAGAC
AAGGACCCGTGGTTCTCGTCTCAACATCATCATTGTGGCTGAGGGTGCAATTGACAAGAATGGAAAACCAATCACCTCAGAAGACATCAA
GAATGGCAGCAGGATGGGTGTGGAAGCAGTGATGGCACTTTTGGAGGGGACCCCAGATACCCCAGCCTGTGTAGTGAGCCTCTCTGGTAA
CCAGGCTGTGCGCCTGCCCCTCATGGAATGTGTCCAGGTGACCAAAGATGTGACCAAGGCCATGGATGAGAAGAAATTTGACGAAGCCCT
GAAGCTGAGAGGCCGGAGCTTCATGAACAACTGGGAGGTGTACAAGCTTCTAGCTCATGTCAGACCCCCGGTATCTAAGAGTGGTTCGCA
CACAGTGGCTGTGATGAACGTGGGGGCTCCGGCTGCAGGCATGAATGCTGCTGTTCGCTCCACTGTGAGGATTGGCCTTATCCAGGGCAA
CCGAGTGCTCGTTGTCCATGATGGTTTCGAGGGCCTGGCCAAGGGGCAGATAAGGAAGCCATTAAGGTCACTCCACTGCCATGTATGCAA
CTGCTGTGTGGCTCGATATGATCAACACTGCCTGTGGACTGGACGGTGCATAGGTTTTGGCAACCATCACTATTACATATTCTTCTTGTT
TTTCCTTTCCATGGTATGTGGCTGGATTATATATGGATCTTTCATCTATTTGTCCAGTCATTGTGCCACAACATTCAAAGAAGATGGATT
ATGGACTTACCTCAATCAGATTGTGGCCTGTTCCCCTTGGGTTTTATATATCTTGATGCTAGCAACTTTCCATTTCTCATGGTCAACATT
TTTATTATTAAATCAACTCTTTCAGATTGCCTTTCTGGGCCTGACCTCCCATGAGAGAATCAGCCTGCAGAAGCAGAGCAAGCATATGAA
ACAGACGTTGTCCCTCAGGAAGACACCATACAATCTTGGATTCATGCAGAACCTGGCAGATTTCTTTCAGTGTGGCTGCTTTGGCTTGGT
GAAGCCCTGTGTGGTAGATTGGACATCACAGTACACCATGGTCTTTCACCCAGCCAGGGAGAAGGTTCTTCGCTCAGTATGAAGAAAAGC
AACCCAAAACTCTCAATCTGATTTGTTTTTGTTTATGTCGATGCCCTGTAGTTTGAAAGTGAAGTAAAGATTTAGAATTCACCTAAGTCC
AAAGGAAAACACGTGGTTTTTAAAGCCATTAGGTAAAAAAAGTTCTCAATAAAGGCATTACAATTTTTTAGGTTTAGAAAGATGGACTTT
TCTGATAAATCTTGGCAGACATCTAAAAAAAAAACCATATTTTTCACAAGAAAATGCAAGTTACTTTTTTTGGAAATAATACTCACTGAT
TATGGATAAAATGGAATATTTTCAGATACTATATTGGCTGTTTCAAAATAGTACTATTCTTTAAACTTGTAATTTTTGCTAAGTTATTTG

>64457_64457_11_PFKM-ZDHHC13_PFKM_chr12_48534654_ENST00000551804_ZDHHC13_chr11_19186598_ENST00000399351_length(amino acids)=606AA_BP=416
MTHEEHHAAKTLGIGKAIAVLTSGGDAQGMNAAVRAVVRVGIFTGARVFFVHEGYQGLVDGGDHIKEATWESVSMMLQLGGTVIGSARCK
DFREREGRLRAAYNLVKRGITNLCVIGGDGSLTGADTFRSEWSDLLSDLQKAGKITDEEATKSSYLNIVGLVGSIDNDFCGTDMTIGTDS
ALHRIMEIVDAITTTAQSHQRTFVLEVMGRHCGYLALVTSLSCGADWVFIPECPPDDDWEEHLCRRLSETRTRGSRLNIIIVAEGAIDKN
GKPITSEDIKNGSRMGVEAVMALLEGTPDTPACVVSLSGNQAVRLPLMECVQVTKDVTKAMDEKKFDEALKLRGRSFMNNWEVYKLLAHV
RPPVSKSGSHTVAVMNVGAPAAGMNAAVRSTVRIGLIQGNRVLVVHDGFEGLAKGQIRKPLRSLHCHVCNCCVARYDQHCLWTGRCIGFG
NHHYYIFFLFFLSMVCGWIIYGSFIYLSSHCATTFKEDGLWTYLNQIVACSPWVLYILMLATFHFSWSTFLLLNQLFQIAFLGLTSHERI

--------------------------------------------------------------
>64457_64457_12_PFKM-ZDHHC13_PFKM_chr12_48534654_ENST00000551804_ZDHHC13_chr11_19186598_ENST00000446113_length(transcript)=2427nt_BP=1399nt
AATATCTGTCTGTTTTTGTCTACGTGCGTGTCATTGTGGGTCTGTAAGGGATGCTTATACATGAGTCTGCATGAATTTCTGTGTCCTGTG
CCTCTATAACTGTCTTAGAGATTTCAGGAGAAGAATATGAGCGGTTTTTACAGAGTGGATCATGACCCATGAAGAGCACCATGCAGCCAA
AACCCTGGGGATTGGCAAAGCCATTGCTGTCTTAACCTCTGGTGGAGATGCCCAAGGTATGAATGCTGCTGTCAGGGCTGTGGTTCGAGT
TGGTATCTTCACCGGTGCCCGTGTCTTCTTTGTCCATGAGGGTTATCAAGGCCTGGTGGATGGTGGAGATCACATCAAGGAAGCCACCTG
GGAGAGCGTTTCGATGATGCTTCAGCTGGGAGGCACGGTGATTGGAAGTGCCCGGTGCAAGGACTTTCGGGAACGAGAAGGACGACTCCG
AGCTGCCTACAACCTGGTGAAGCGTGGGATCACCAATCTCTGTGTCATTGGGGGTGATGGCAGCCTCACTGGGGCTGACACCTTCCGTTC
TGAGTGGAGTGACTTGTTGAGTGACCTCCAGAAAGCAGGTAAGATCACAGATGAGGAGGCTACGAAGTCCAGCTACCTGAACATTGTGGG
CCTGGTTGGGTCAATTGACAATGACTTCTGTGGCACCGATATGACCATTGGCACTGACTCTGCCCTGCATCGGATCATGGAAATTGTAGA
TGCCATCACTACCACTGCCCAGAGCCACCAGAGGACATTTGTGTTAGAAGTAATGGGCCGCCACTGTGGATACCTGGCCCTTGTCACCTC
TCTGTCCTGTGGGGCCGACTGGGTTTTTATTCCTGAATGTCCACCAGATGACGACTGGGAGGAACACCTTTGTCGCCGACTCAGCGAGAC
AAGGACCCGTGGTTCTCGTCTCAACATCATCATTGTGGCTGAGGGTGCAATTGACAAGAATGGAAAACCAATCACCTCAGAAGACATCAA
GAATGGCAGCAGGATGGGTGTGGAAGCAGTGATGGCACTTTTGGAGGGGACCCCAGATACCCCAGCCTGTGTAGTGAGCCTCTCTGGTAA
CCAGGCTGTGCGCCTGCCCCTCATGGAATGTGTCCAGGTGACCAAAGATGTGACCAAGGCCATGGATGAGAAGAAATTTGACGAAGCCCT
GAAGCTGAGAGGCCGGAGCTTCATGAACAACTGGGAGGTGTACAAGCTTCTAGCTCATGTCAGACCCCCGGTATCTAAGAGTGGTTCGCA
CACAGTGGCTGTGATGAACGTGGGGGCTCCGGCTGCAGGCATGAATGCTGCTGTTCGCTCCACTGTGAGGATTGGCCTTATCCAGGGCAA
CCGAGTGCTCGTTGTCCATGATGGTTTCGAGGGCCTGGCCAAGGGGCAGATAAGGAAGCCATTAAGGTCACTCCACTGCCATGTATGCAA
CTGCTGTGTGGCTCGATATGATCAACACTGCCTGTGGACTGGACGGTGCATAGGTTTTGGCAACCATCACTATTACATATTCTTCTTGTT
TTTCCTTTCCATGGTATGTGGCTGGATTATATATGGATCTTTCATCTATTTGTCCAGTCATTGTGCCACAACATTCAAAGAAGATGGATT
ATGGACTTACCTCAATCAGATTGTGGCCTGTTCCCCTTGGGTTTTATATATCTTGATGCTAGCAACTTTCCATTTCTCATGGTCAACATT
TTTATTATTAAATCAACTCTTTCAGATTGCCTTTCTGGGCCTGACCTCCCATGAGAGAATCAGCCTGCAGAAGCAGAGCAAGCATATGAA
ACAGACGTTGTCCCTCAGGAAGACACCATACAATCTTGGATTCATGCAGAACCTGGCAGATTTCTTTCAGTGTGGCTGCTTTGGCTTGGT
GAAGCCCTGTGTGGTAGATTGGACATCACAGTACACCATGGTCTTTCACCCAGCCAGGGAGAAGGTTCTTCGCTCAGTATGAAGAAAAGC
AACCCAAAACTCTCAATCTGATTTGTTTTTGTTTATGTCGATGCCCTGTAGTTTGAAAGTGAAGTAAAGATTTAGAATTCACCTAAGTCC
AAAGGAAAACACGTGGTTTTTAAAGCCATTAGGTAAAAAAAGTTCTCAATAAAGGCATTACAATTTTTTAGGTTTAGAAAGATGGACTTT
TCTGATAAATCTTGGCAGACATCTAAAAAAAAAACCATATTTTTCACAAGAAAATGCAAGTTACTTTTTTTGGAAATAATACTCACTGAT
TATGGATAAAATGGAATATTTTCAGATACTATATTGGCTGTTTCAAAATAGTACTATTCTTTAAACTTGTAATTTTTGCTAAGTTATTTG

>64457_64457_12_PFKM-ZDHHC13_PFKM_chr12_48534654_ENST00000551804_ZDHHC13_chr11_19186598_ENST00000446113_length(amino acids)=606AA_BP=416
MTHEEHHAAKTLGIGKAIAVLTSGGDAQGMNAAVRAVVRVGIFTGARVFFVHEGYQGLVDGGDHIKEATWESVSMMLQLGGTVIGSARCK
DFREREGRLRAAYNLVKRGITNLCVIGGDGSLTGADTFRSEWSDLLSDLQKAGKITDEEATKSSYLNIVGLVGSIDNDFCGTDMTIGTDS
ALHRIMEIVDAITTTAQSHQRTFVLEVMGRHCGYLALVTSLSCGADWVFIPECPPDDDWEEHLCRRLSETRTRGSRLNIIIVAEGAIDKN
GKPITSEDIKNGSRMGVEAVMALLEGTPDTPACVVSLSGNQAVRLPLMECVQVTKDVTKAMDEKKFDEALKLRGRSFMNNWEVYKLLAHV
RPPVSKSGSHTVAVMNVGAPAAGMNAAVRSTVRIGLIQGNRVLVVHDGFEGLAKGQIRKPLRSLHCHVCNCCVARYDQHCLWTGRCIGFG
NHHYYIFFLFFLSMVCGWIIYGSFIYLSSHCATTFKEDGLWTYLNQIVACSPWVLYILMLATFHFSWSTFLLLNQLFQIAFLGLTSHERI

--------------------------------------------------------------

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Fusion Gene PPI Analysis for PFKM-ZDHHC13


check button Go to ChiPPI (Chimeric Protein-Protein interactions) to see the chimeric PPI interaction in

ChiPPI page.


check button Protein-protein interactors with each fusion partner protein in wild-type (BIOGRID-3.4.160)
HgeneHgene's interactorsTgeneTgene's interactors


check button - Retained PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenStill interaction with


check button - Lost PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


check button - Retained PPIs, but lost function due to frame-shift fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


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Related Drugs for PFKM-ZDHHC13


check button Drugs targeting genes involved in this fusion gene.
(DrugBank Version 5.1.8 2021-05-08)
PartnerGeneUniProtAccDrugBank IDDrug nameDrug activityDrug typeDrug status

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Related Diseases for PFKM-ZDHHC13


check button Diseases associated with fusion partners.
(DisGeNet 4.0)
PartnerGeneDisease IDDisease name# pubmedsSource