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 | Fusion Gene Summary |
| Fusion Gene ORF analysis |
| Fusion Genomic Features |
| Fusion Protein Features |
| Fusion Gene Sequence |
| Fusion Gene PPI analysis |
| Related Drugs |
| Related Diseases |
Fusion gene:PGPEP1-GTF2F1 (FusionGDB2 ID:64649) |
Fusion Gene Summary for PGPEP1-GTF2F1 |
 Fusion gene summary |
| Fusion gene information | Fusion gene name: PGPEP1-GTF2F1 | Fusion gene ID: 64649 | Hgene | Tgene | Gene symbol | PGPEP1 | GTF2F1 | Gene ID | 54858 | 2962 |
| Gene name | pyroglutamyl-peptidase I | general transcription factor IIF subunit 1 | |
| Synonyms | PAP-I|PGI|PGP|PGP-I|PGPI|Pcp | BTF4|RAP74|TF2F1|TFIIF | |
| Cytomap | 19p13.11 | 19p13.3 | |
| Type of gene | protein-coding | protein-coding | |
| Description | pyroglutamyl-peptidase 15-oxoprolyl-peptidasepGlu-peptidase Ipyroglutamyl aminopeptidase Ipyrrolidone-carboxylate peptidase | general transcription factor IIF subunit 1TFIIF-alphageneral transcription factor IIF 74 kDa subunitgeneral transcription factor IIF, polypeptide 1, 74kDatranscription initiation factor IIF subunit alphatranscription initiation factor RAP74 | |
| Modification date | 20200313 | 20200313 | |
| UniProtAcc | . | P35269 | |
| Ensembl transtripts involved in fusion gene | ENST00000252813, ENST00000269919, ENST00000595066, ENST00000597431, ENST00000604499, | ENST00000394456, ENST00000429701, | |
| Fusion gene scores | * DoF score | 7 X 5 X 6=210 | 5 X 4 X 4=80 |
| # samples | 8 | 5 | |
| ** MAII score | log2(8/210*10)=-1.39231742277876 possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs). DoF>8 and MAII<0 | log2(5/80*10)=-0.678071905112638 possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs). DoF>8 and MAII<0 | |
| Context | PubMed: PGPEP1 [Title/Abstract] AND GTF2F1 [Title/Abstract] AND fusion [Title/Abstract] | ||
| Most frequent breakpoint | PGPEP1(18466821)-GTF2F1(6389648), # samples:1 | ||
| Anticipated loss of major functional domain due to fusion event. | |||
| * DoF score (Degree of Frequency) = # partners X # break points X # cancer types ** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10) |
| Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez |
| Partner | Gene | GO ID | GO term | PubMed ID |
| Fusion gene breakpoints across PGPEP1 (5'-gene) * Click on the image to open the UCSC genome browser with custom track showing this image in a new window. |
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| Fusion gene breakpoints across GTF2F1 (3'-gene) * Click on the image to open the UCSC genome browser with custom track showing this image in a new window. |
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| Fusion gene information from two resources (ChiTars 5.0 and ChimerDB 4.0) * All genome coordinats were lifted-over on hg19. * Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser. |
| Source | Disease | Sample | Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand |
| ChimerDB4 | SARC | TCGA-DX-A8BL-01A | PGPEP1 | chr19 | 18466821 | + | GTF2F1 | chr19 | 6389648 | - |
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Fusion Gene ORF analysis for PGPEP1-GTF2F1 |
| Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure. * Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser. |
| ORF | Henst | Tenst | Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand |
| 5UTR-3CDS | ENST00000252813 | ENST00000394456 | PGPEP1 | chr19 | 18466821 | + | GTF2F1 | chr19 | 6389648 | - |
| 5UTR-3CDS | ENST00000252813 | ENST00000429701 | PGPEP1 | chr19 | 18466821 | + | GTF2F1 | chr19 | 6389648 | - |
| In-frame | ENST00000269919 | ENST00000394456 | PGPEP1 | chr19 | 18466821 | + | GTF2F1 | chr19 | 6389648 | - |
| In-frame | ENST00000269919 | ENST00000429701 | PGPEP1 | chr19 | 18466821 | + | GTF2F1 | chr19 | 6389648 | - |
| In-frame | ENST00000595066 | ENST00000394456 | PGPEP1 | chr19 | 18466821 | + | GTF2F1 | chr19 | 6389648 | - |
| In-frame | ENST00000595066 | ENST00000429701 | PGPEP1 | chr19 | 18466821 | + | GTF2F1 | chr19 | 6389648 | - |
| In-frame | ENST00000597431 | ENST00000394456 | PGPEP1 | chr19 | 18466821 | + | GTF2F1 | chr19 | 6389648 | - |
| In-frame | ENST00000597431 | ENST00000429701 | PGPEP1 | chr19 | 18466821 | + | GTF2F1 | chr19 | 6389648 | - |
| In-frame | ENST00000604499 | ENST00000394456 | PGPEP1 | chr19 | 18466821 | + | GTF2F1 | chr19 | 6389648 | - |
| In-frame | ENST00000604499 | ENST00000429701 | PGPEP1 | chr19 | 18466821 | + | GTF2F1 | chr19 | 6389648 | - |
| ORFfinder result based on the fusion transcript sequence of in-frame fusion genes. |
| Henst | Tenst | Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand | Seq length (transcript) | BP loci (transcript) | Predicted start (transcript) | Predicted stop (transcript) | Seq length (amino acids) |
| ENST00000269919 | PGPEP1 | chr19 | 18466821 | + | ENST00000394456 | GTF2F1 | chr19 | 6389648 | - | 2433 | 299 | 95 | 1720 | 541 |
| ENST00000269919 | PGPEP1 | chr19 | 18466821 | + | ENST00000429701 | GTF2F1 | chr19 | 6389648 | - | 1953 | 299 | 95 | 1549 | 484 |
| ENST00000604499 | PGPEP1 | chr19 | 18466821 | + | ENST00000394456 | GTF2F1 | chr19 | 6389648 | - | 2422 | 288 | 84 | 1709 | 541 |
| ENST00000604499 | PGPEP1 | chr19 | 18466821 | + | ENST00000429701 | GTF2F1 | chr19 | 6389648 | - | 1942 | 288 | 84 | 1538 | 484 |
| ENST00000595066 | PGPEP1 | chr19 | 18466821 | + | ENST00000394456 | GTF2F1 | chr19 | 6389648 | - | 2421 | 287 | 83 | 1708 | 541 |
| ENST00000595066 | PGPEP1 | chr19 | 18466821 | + | ENST00000429701 | GTF2F1 | chr19 | 6389648 | - | 1941 | 287 | 83 | 1537 | 484 |
| ENST00000597431 | PGPEP1 | chr19 | 18466821 | + | ENST00000394456 | GTF2F1 | chr19 | 6389648 | - | 2381 | 247 | 43 | 1668 | 541 |
| ENST00000597431 | PGPEP1 | chr19 | 18466821 | + | ENST00000429701 | GTF2F1 | chr19 | 6389648 | - | 1901 | 247 | 43 | 1497 | 484 |
| DeepORF prediction of the coding potential based on the fusion transcript sequence of in-frame fusion genes. DeepORF is a coding potential classifier based on convolutional neural network by comparing the real Ribo-seq data. If the no-coding score < 0.5 and coding score > 0.5, then the in-frame fusion transcript is predicted as being likely translated. |
| Henst | Tenst | Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand | No-coding score | Coding score |
| ENST00000269919 | ENST00000394456 | PGPEP1 | chr19 | 18466821 | + | GTF2F1 | chr19 | 6389648 | - | 0.016843382 | 0.9831566 |
| ENST00000269919 | ENST00000429701 | PGPEP1 | chr19 | 18466821 | + | GTF2F1 | chr19 | 6389648 | - | 0.013270115 | 0.98672986 |
| ENST00000604499 | ENST00000394456 | PGPEP1 | chr19 | 18466821 | + | GTF2F1 | chr19 | 6389648 | - | 0.01703881 | 0.98296124 |
| ENST00000604499 | ENST00000429701 | PGPEP1 | chr19 | 18466821 | + | GTF2F1 | chr19 | 6389648 | - | 0.013152606 | 0.98684734 |
| ENST00000595066 | ENST00000394456 | PGPEP1 | chr19 | 18466821 | + | GTF2F1 | chr19 | 6389648 | - | 0.0170424 | 0.98295754 |
| ENST00000595066 | ENST00000429701 | PGPEP1 | chr19 | 18466821 | + | GTF2F1 | chr19 | 6389648 | - | 0.013189701 | 0.9868103 |
| ENST00000597431 | ENST00000394456 | PGPEP1 | chr19 | 18466821 | + | GTF2F1 | chr19 | 6389648 | - | 0.016062515 | 0.98393744 |
| ENST00000597431 | ENST00000429701 | PGPEP1 | chr19 | 18466821 | + | GTF2F1 | chr19 | 6389648 | - | 0.013352038 | 0.9866479 |
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Fusion Genomic Features for PGPEP1-GTF2F1 |
| FusionAI prediction of the potential fusion gene breakpoint based on the pre-mature RNA sequence context (+/- 5kb of individual partner genes, total 20kb length sequence). FusionAI is a fusion gene breakpoint classifier based on convolutional neural network by comparing the fusion positive and negative sequence context of ~ 20K fusion gene data. From here, we can have the relative potentency of the 20K genomic sequence how individual sequnce will be likely used as the gene fusion breakpoints. |
| Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand | 1-p | p (fusion gene breakpoint) |
| Distribution of 44 human genomic features loci across 20kb length fusion breakpoint regions. We integrated a total of 44 different types of human genomic feature loci information across five big categories including virus integration sites, repeats, structural variants, chromatin states, and gene expression regulation. More details are in help page. |
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| Distribution of 44 human genomic features loci across 20kb length fusion breakpoint regions that are ovelapped with the top 1% feature importance score regions. More details are in help page. |
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Fusion Protein Features for PGPEP1-GTF2F1 |
| Four levels of functional features of fusion genes Go to FGviewer search page for the most frequent breakpoint (https://ccsmweb.uth.edu/FGviewer/chr19:18466821/chr19:6389648) - FGviewer provides the online visualization of the retention search of the protein functional features across DNA, RNA, protein, and pathological levels. - How to search 1. Put your fusion gene symbol. 2. Press the tab key until there will be shown the breakpoint information filled. 4. Go down and press 'Search' tab twice. 4. Go down to have the hyperlink of the search result. 5. Click the hyperlink. 6. See the FGviewer result for your fusion gene. |
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| Main function of each fusion partner protein. (from UniProt) |
| Hgene | Tgene |
| . | GTF2F1 |
| FUNCTION: Transcriptional activator which is required for calcium-dependent dendritic growth and branching in cortical neurons. Recruits CREB-binding protein (CREBBP) to nuclear bodies. Component of the CREST-BRG1 complex, a multiprotein complex that regulates promoter activation by orchestrating a calcium-dependent release of a repressor complex and a recruitment of an activator complex. In resting neurons, transcription of the c-FOS promoter is inhibited by BRG1-dependent recruitment of a phospho-RB1-HDAC1 repressor complex. Upon calcium influx, RB1 is dephosphorylated by calcineurin, which leads to release of the repressor complex. At the same time, there is increased recruitment of CREBBP to the promoter by a CREST-dependent mechanism, which leads to transcriptional activation. The CREST-BRG1 complex also binds to the NR2B promoter, and activity-dependent induction of NR2B expression involves a release of HDAC1 and recruitment of CREBBP (By similarity). {ECO:0000250}. | FUNCTION: TFIIF is a general transcription initiation factor that binds to RNA polymerase II and helps to recruit it to the initiation complex in collaboration with TFIIB. It promotes transcription elongation. {ECO:0000269|PubMed:10428810}. |
| Retention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at * Minus value of BPloci means that the break pointn is located before the CDS. |
| - In-frame and retained protein feature among the 13 regional features. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Protein feature | Protein feature note |
| Tgene | GTF2F1 | chr19:18466821 | chr19:6389648 | ENST00000394456 | 2 | 13 | 283_350 | 44 | 518.0 | Compositional bias | Note=Glu-rich |
| - In-frame and not-retained protein feature among the 13 regional features. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Protein feature | Protein feature note |
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Fusion Gene Sequence for PGPEP1-GTF2F1 |
| For in-frame fusion transcripts, we provide the fusion transcript sequences and fusion amino acid sequences. To have fusion amino acid sequence, we ran ORFfinder and chose the longest ORF among the all predicted ones. |
| >64649_64649_1_PGPEP1-GTF2F1_PGPEP1_chr19_18466821_ENST00000269919_GTF2F1_chr19_6389648_ENST00000394456_length(transcript)=2433nt_BP=299nt AGGGGCGTGGCCTCGCGCGGCCGAGAGGCTGCAGCGGCAGCAGCTGTCGCGCCAGTCGCAACAGAAGCAGGTCCGAGGCACAGCCCGATC CCGCCATGGAGCAGCCGAGGAAGGCGGTGGTAGTGACGGGATTTGGCCCTTTTGGGGAACACACCGTGAACGCCAGTTGGATTGCAGTTC AGGAGCTAGAAAAGCTAGGCCTTGGCGACAGCGTGGACCTGCATGTGTACGAGATTCCGGTTGAGTACCAAACAGTCCAGAGACTCATCC CCGCCCTGTGGGAGAAGCACAGTCCACAGGCTCGGCTGGAGCGGGACTTGAGCAACAAGAAAATCTACCAAGAGGAGGAGATGCCCGAAT CGGGCGCGGGCAGTGAGTTCAACCGCAAGCTTCGGGAGGAGGCTCGGAGGAAGAAGTACGGCATCGTCCTCAAGGAGTTCCGGCCCGAGG ACCAGCCCTGGCTGCTCCGGGTCAACGGCAAATCAGGCAGGAAGTTCAAGGGCATCAAGAAGGGAGGCGTAACAGAGAACACGTCCTACT ACATCTTCACCCAGTGCCCCGACGGGGCCTTCGAGGCCTTCCCCGTGCACAACTGGTACAATTTCACACCGCTGGCCCGGCATCGCACGC TCACTGCCGAGGAGGCCGAGGAGGAGTGGGAGAGGAGGAACAAGGTGCTGAACCACTTCAGCATCATGCAGCAGCGGCGGCTCAAGGATC AGGACCAGGACGAGGATGAGGAGGAGAAGGAGAAACGTGGCCGCAGGAAGGCGAGCGAGCTGCGCATCCACGACCTGGAGGACGACCTGG AGATGTCGTCCGATGCCAGTGATGCCAGTGGTGAGGAGGGGGGCAGAGTCCCCAAGGCCAAGAAGAAGGCGCCGCTGGCCAAGGGCGGCA GGAAAAAGAAGAAGAAGAAGGGTTCAGACGACGAGGCCTTCGAGGACAGCGATGATGGGGACTTCGAGGGCCAAGAGGTGGACTACATGT CAGACGGCTCCAGTAGCTCCCAAGAAGAGCCTGAGAGCAAGGCCAAGGCGCCGCAGCAGGAGGAGGGGCCCAAGGGTGTCGATGAGCAGA GCGACAGTAGTGAGGAGAGTGAGGAGGAGAAGCCGCCTGAGGAGGACAAGGAGGAGGAGGAGGAGAAGAAGGCACCCACCCCGCAGGAGA AGAAGCGCAGGAAAGACAGCAGCGAGGAGTCGGACAGCTCAGAGGAGAGCGACATTGACAGCGAGGCCTCCTCAGCCCTCTTCATGGCGA AGAAGAAGACGCCACCCAAGAGAGAGCGGAAGCCGTCGGGAGGGAGCTCAAGGGGCAACAGCCGCCCAGGCACGCCCAGCGCAGAGGGTG GCAGCACCTCCTCCACCCTGCGGGCGGCTGCCAGCAAACTCGAGCAAGGGAAGCGGGTGAGCGAGATGCCTGCAGCCAAGCGGTTGCGGC TGGACACGGGACCCCAGAGCCTGTCTGGGAAGTCGACACCCCAGCCACCATCAGGCAAGACAACACCCAACAGCGGCGACGTGCAGGTGA CTGAGGATGCCGTGCGCCGCTACCTGACACGGAAGCCCATGACCACTAAGGACCTGCTGAAAAAGTTCCAGACCAAGAAGACAGGGCTGA GCAGCGAGCAGACAGTGAACGTGTTGGCCCAGATCCTCAAGCGACTCAACCCCGAGCGCAAGATGATCAACGACAAAATGCACTTCTCCC TCAAGGAGTGAGGCTTGGTCCAATACATGGCTCTGCCCCCCAGAACTTAAGGCTCTCACTGCCCCTTCGCCATCCTAGAGTGAGGCTCTG TCCAATACATGGCTCTGCCCTCCAGAACTTCAGGCTCTCAGTGACCCTTCGACATCCTGCTTGCTCCCTGACTCCCAGGGCCCCGTAGTT AGCAATTCTGGAAAAGTTAAGCCATCTCCTCCTCTGGCCCTTCCTTCTGGAATCTTCAGATGCCTGTTAGGCCTTCTTATTGTCCTCCTC CTCCTGGCTCGGCCTCCCTCACACTGACCAAGGGCCTGTGCTGCCCACTGGGTAACTTCTACAGTTCTCCCTTCCACTTCCCTAAGTCTC TCTTCAGCTGTGACTTATCCACCACATAGCCCAGTAAGTCTTCAGTTTTGGCTGGGCATGATGGTGAGCGCCTGCAGTCCCAGCTACTTG GGAGGCTAAGCCCAGTTCAAGGCTGCAGTGAACTATGATGGTGCCACTGCATTCCAGCCTGGGTGACAGAATGAAATCCTGGCACAAAAA AAAAAAAAAAGTAGCCAGGCATGGTGGCGGGAGCCTGTTGTCCCAGCTGTTCCGTAGGCTGAGGCACGAGATTCACTTGAACCTGGGAGG TGGAGGTTGCTGTGAGCTGACACCACGCCACTGCACTCCAGCCTGGGTGACAGTGAGACTCTGTCTCAATAAATAAAAAATAATAATAAA >64649_64649_1_PGPEP1-GTF2F1_PGPEP1_chr19_18466821_ENST00000269919_GTF2F1_chr19_6389648_ENST00000394456_length(amino acids)=541AA_BP=66 MEQPRKAVVVTGFGPFGEHTVNASWIAVQELEKLGLGDSVDLHVYEIPVEYQTVQRLIPALWEKHSPQARLERDLSNKKIYQEEEMPESG AGSEFNRKLREEARRKKYGIVLKEFRPEDQPWLLRVNGKSGRKFKGIKKGGVTENTSYYIFTQCPDGAFEAFPVHNWYNFTPLARHRTLT AEEAEEEWERRNKVLNHFSIMQQRRLKDQDQDEDEEEKEKRGRRKASELRIHDLEDDLEMSSDASDASGEEGGRVPKAKKKAPLAKGGRK KKKKKGSDDEAFEDSDDGDFEGQEVDYMSDGSSSSQEEPESKAKAPQQEEGPKGVDEQSDSSEESEEEKPPEEDKEEEEEKKAPTPQEKK RRKDSSEESDSSEESDIDSEASSALFMAKKKTPPKRERKPSGGSSRGNSRPGTPSAEGGSTSSTLRAAASKLEQGKRVSEMPAAKRLRLD TGPQSLSGKSTPQPPSGKTTPNSGDVQVTEDAVRRYLTRKPMTTKDLLKKFQTKKTGLSSEQTVNVLAQILKRLNPERKMINDKMHFSLK -------------------------------------------------------------- >64649_64649_2_PGPEP1-GTF2F1_PGPEP1_chr19_18466821_ENST00000269919_GTF2F1_chr19_6389648_ENST00000429701_length(transcript)=1953nt_BP=299nt AGGGGCGTGGCCTCGCGCGGCCGAGAGGCTGCAGCGGCAGCAGCTGTCGCGCCAGTCGCAACAGAAGCAGGTCCGAGGCACAGCCCGATC CCGCCATGGAGCAGCCGAGGAAGGCGGTGGTAGTGACGGGATTTGGCCCTTTTGGGGAACACACCGTGAACGCCAGTTGGATTGCAGTTC AGGAGCTAGAAAAGCTAGGCCTTGGCGACAGCGTGGACCTGCATGTGTACGAGATTCCGGTTGAGTACCAAACAGTCCAGAGACTCATCC CCGCCCTGTGGGAGAAGCACAGTCCACAGGCTCGGCTGGAGCGGGACTTGAGCAACAAGAAAATCTACCAAGAGGAGGAGATGCCCGAAT CGGGCGCGGGCAGTGAGTTCAACCGCAAGCTTCGGGAGGAGGCTCGGAGGAAGAAGTACGGCATCGTCCTCAAGGAGTTCCGGCCCGAGG ACCAGCCCTGGCTGCTCCGGGTCAACGGCAAATCAGGCAGGAAGAGGAACAAGGTGCTGAACCACTTCAGCATCATGCAGCAGCGGCGGC TCAAGGATCAGGACCAGGACGAGGATGAGGAGGAGAAGGAGAAACGTGGCCGCAGGAAGGCGAGCGAGCTGCGCATCCACGACCTGGAGG ACGACCTGGAGATGTCGTCCGATGCCAGTGATGCCAGTGGTGAGGAGGGGGGCAGAGTCCCCAAGGCCAAGAAGAAGGCGCCGCTGGCCA AGGGCGGCAGGAAAAAGAAGAAGAAGAAGGGTTCAGACGACGAGGCCTTCGAGGACAGCGATGATGGGGACTTCGAGGGCCAAGAGGTGG ACTACATGTCAGACGGCTCCAGTAGCTCCCAAGAAGAGCCTGAGAGCAAGGCCAAGGCGCCGCAGCAGGAGGAGGGGCCCAAGGGTGTCG ATGAGCAGAGCGACAGTAGTGAGGAGAGTGAGGAGGAGAAGCCGCCTGAGGAGGACAAGGAGGAGGAGGAGGAGAAGAAGGCACCCACCC CGCAGGAGAAGAAGCGCAGGAAAGACAGCAGCGAGGAGTCGGACAGCTCAGAGGAGAGCGACATTGACAGCGAGGCCTCCTCAGCCCTCT TCATGGCGAAGAAGAAGACGCCACCCAAGAGAGAGCGGAAGCCGTCGGGAGGGAGCTCAAGGGGCAACAGCCGCCCAGGCACGCCCAGCG CAGAGGGTGGCAGCACCTCCTCCACCCTGCGGGCGGCTGCCAGCAAACTCGAGCAAGGGAAGCGGGTGAGCGAGATGCCTGCAGCCAAGC GGTTGCGGCTGGACACGGGACCCCAGAGCCTGTCTGGGAAGTCGACACCCCAGCCACCATCAGGCAAGACAACACCCAACAGCGGCGACG TGCAGGTGACTGAGGATGCCGTGCGCCGCTACCTGACACGGAAGCCCATGACCACTAAGGACCTGCTGAAAAAGTTCCAGACCAAGAAGA CAGGGCTGAGCAGCGAGCAGACAGTGAACGTGTTGGCCCAGATCCTCAAGCGACTCAACCCCGAGCGCAAGATGATCAACGACAAAATGC ACTTCTCCCTCAAGGAGTGAGGCTTGGTCCAATACATGGCTCTGCCCCCCAGAACTTAAGGCTCTCACTGCCCCTTCGCCATCCTAGAGT GAGGCTCTGTCCAATACATGGCTCTGCCCTCCAGAACTTCAGGCTCTCAGTGACCCTTCGACATCCTGCTTGCTCCCTGACTCCCAGGGC CCCGTAGTTAGCAATTCTGGAAAAGTTAAGCCATCTCCTCCTCTGGCCCTTCCTTCTGGAATCTTCAGATGCCTGTTAGGCCTTCTTATT GTCCTCCTCCTCCTGGCTCGGCCTCCCTCACACTGACCAAGGGCCTGTGCTGCCCACTGGGTAACTTCTACAGTTCTCCCTTCCACTTCC >64649_64649_2_PGPEP1-GTF2F1_PGPEP1_chr19_18466821_ENST00000269919_GTF2F1_chr19_6389648_ENST00000429701_length(amino acids)=484AA_BP=66 MEQPRKAVVVTGFGPFGEHTVNASWIAVQELEKLGLGDSVDLHVYEIPVEYQTVQRLIPALWEKHSPQARLERDLSNKKIYQEEEMPESG AGSEFNRKLREEARRKKYGIVLKEFRPEDQPWLLRVNGKSGRKRNKVLNHFSIMQQRRLKDQDQDEDEEEKEKRGRRKASELRIHDLEDD LEMSSDASDASGEEGGRVPKAKKKAPLAKGGRKKKKKKGSDDEAFEDSDDGDFEGQEVDYMSDGSSSSQEEPESKAKAPQQEEGPKGVDE QSDSSEESEEEKPPEEDKEEEEEKKAPTPQEKKRRKDSSEESDSSEESDIDSEASSALFMAKKKTPPKRERKPSGGSSRGNSRPGTPSAE GGSTSSTLRAAASKLEQGKRVSEMPAAKRLRLDTGPQSLSGKSTPQPPSGKTTPNSGDVQVTEDAVRRYLTRKPMTTKDLLKKFQTKKTG -------------------------------------------------------------- >64649_64649_3_PGPEP1-GTF2F1_PGPEP1_chr19_18466821_ENST00000595066_GTF2F1_chr19_6389648_ENST00000394456_length(transcript)=2421nt_BP=287nt TCGCGCGGCCGAGAGGCTGCAGCGGCAGCAGCTGTCGCGCCAGTCGCAACAGAAGCAGGTCCGAGGCACAGCCCGATCCCGCCATGGAGC AGCCGAGGAAGGCGGTGGTAGTGACGGGATTTGGCCCTTTTGGGGAACACACCGTGAACGCCAGTTGGATTGCAGTTCAGGAGCTAGAAA AGCTAGGCCTTGGCGACAGCGTGGACCTGCATGTGTACGAGATTCCGGTTGAGTACCAAACAGTCCAGAGACTCATCCCCGCCCTGTGGG AGAAGCACAGTCCACAGGCTCGGCTGGAGCGGGACTTGAGCAACAAGAAAATCTACCAAGAGGAGGAGATGCCCGAATCGGGCGCGGGCA GTGAGTTCAACCGCAAGCTTCGGGAGGAGGCTCGGAGGAAGAAGTACGGCATCGTCCTCAAGGAGTTCCGGCCCGAGGACCAGCCCTGGC TGCTCCGGGTCAACGGCAAATCAGGCAGGAAGTTCAAGGGCATCAAGAAGGGAGGCGTAACAGAGAACACGTCCTACTACATCTTCACCC AGTGCCCCGACGGGGCCTTCGAGGCCTTCCCCGTGCACAACTGGTACAATTTCACACCGCTGGCCCGGCATCGCACGCTCACTGCCGAGG AGGCCGAGGAGGAGTGGGAGAGGAGGAACAAGGTGCTGAACCACTTCAGCATCATGCAGCAGCGGCGGCTCAAGGATCAGGACCAGGACG AGGATGAGGAGGAGAAGGAGAAACGTGGCCGCAGGAAGGCGAGCGAGCTGCGCATCCACGACCTGGAGGACGACCTGGAGATGTCGTCCG ATGCCAGTGATGCCAGTGGTGAGGAGGGGGGCAGAGTCCCCAAGGCCAAGAAGAAGGCGCCGCTGGCCAAGGGCGGCAGGAAAAAGAAGA AGAAGAAGGGTTCAGACGACGAGGCCTTCGAGGACAGCGATGATGGGGACTTCGAGGGCCAAGAGGTGGACTACATGTCAGACGGCTCCA GTAGCTCCCAAGAAGAGCCTGAGAGCAAGGCCAAGGCGCCGCAGCAGGAGGAGGGGCCCAAGGGTGTCGATGAGCAGAGCGACAGTAGTG AGGAGAGTGAGGAGGAGAAGCCGCCTGAGGAGGACAAGGAGGAGGAGGAGGAGAAGAAGGCACCCACCCCGCAGGAGAAGAAGCGCAGGA AAGACAGCAGCGAGGAGTCGGACAGCTCAGAGGAGAGCGACATTGACAGCGAGGCCTCCTCAGCCCTCTTCATGGCGAAGAAGAAGACGC CACCCAAGAGAGAGCGGAAGCCGTCGGGAGGGAGCTCAAGGGGCAACAGCCGCCCAGGCACGCCCAGCGCAGAGGGTGGCAGCACCTCCT CCACCCTGCGGGCGGCTGCCAGCAAACTCGAGCAAGGGAAGCGGGTGAGCGAGATGCCTGCAGCCAAGCGGTTGCGGCTGGACACGGGAC CCCAGAGCCTGTCTGGGAAGTCGACACCCCAGCCACCATCAGGCAAGACAACACCCAACAGCGGCGACGTGCAGGTGACTGAGGATGCCG TGCGCCGCTACCTGACACGGAAGCCCATGACCACTAAGGACCTGCTGAAAAAGTTCCAGACCAAGAAGACAGGGCTGAGCAGCGAGCAGA CAGTGAACGTGTTGGCCCAGATCCTCAAGCGACTCAACCCCGAGCGCAAGATGATCAACGACAAAATGCACTTCTCCCTCAAGGAGTGAG GCTTGGTCCAATACATGGCTCTGCCCCCCAGAACTTAAGGCTCTCACTGCCCCTTCGCCATCCTAGAGTGAGGCTCTGTCCAATACATGG CTCTGCCCTCCAGAACTTCAGGCTCTCAGTGACCCTTCGACATCCTGCTTGCTCCCTGACTCCCAGGGCCCCGTAGTTAGCAATTCTGGA AAAGTTAAGCCATCTCCTCCTCTGGCCCTTCCTTCTGGAATCTTCAGATGCCTGTTAGGCCTTCTTATTGTCCTCCTCCTCCTGGCTCGG CCTCCCTCACACTGACCAAGGGCCTGTGCTGCCCACTGGGTAACTTCTACAGTTCTCCCTTCCACTTCCCTAAGTCTCTCTTCAGCTGTG ACTTATCCACCACATAGCCCAGTAAGTCTTCAGTTTTGGCTGGGCATGATGGTGAGCGCCTGCAGTCCCAGCTACTTGGGAGGCTAAGCC CAGTTCAAGGCTGCAGTGAACTATGATGGTGCCACTGCATTCCAGCCTGGGTGACAGAATGAAATCCTGGCACAAAAAAAAAAAAAAAGT AGCCAGGCATGGTGGCGGGAGCCTGTTGTCCCAGCTGTTCCGTAGGCTGAGGCACGAGATTCACTTGAACCTGGGAGGTGGAGGTTGCTG >64649_64649_3_PGPEP1-GTF2F1_PGPEP1_chr19_18466821_ENST00000595066_GTF2F1_chr19_6389648_ENST00000394456_length(amino acids)=541AA_BP=66 MEQPRKAVVVTGFGPFGEHTVNASWIAVQELEKLGLGDSVDLHVYEIPVEYQTVQRLIPALWEKHSPQARLERDLSNKKIYQEEEMPESG AGSEFNRKLREEARRKKYGIVLKEFRPEDQPWLLRVNGKSGRKFKGIKKGGVTENTSYYIFTQCPDGAFEAFPVHNWYNFTPLARHRTLT AEEAEEEWERRNKVLNHFSIMQQRRLKDQDQDEDEEEKEKRGRRKASELRIHDLEDDLEMSSDASDASGEEGGRVPKAKKKAPLAKGGRK KKKKKGSDDEAFEDSDDGDFEGQEVDYMSDGSSSSQEEPESKAKAPQQEEGPKGVDEQSDSSEESEEEKPPEEDKEEEEEKKAPTPQEKK RRKDSSEESDSSEESDIDSEASSALFMAKKKTPPKRERKPSGGSSRGNSRPGTPSAEGGSTSSTLRAAASKLEQGKRVSEMPAAKRLRLD TGPQSLSGKSTPQPPSGKTTPNSGDVQVTEDAVRRYLTRKPMTTKDLLKKFQTKKTGLSSEQTVNVLAQILKRLNPERKMINDKMHFSLK -------------------------------------------------------------- >64649_64649_4_PGPEP1-GTF2F1_PGPEP1_chr19_18466821_ENST00000595066_GTF2F1_chr19_6389648_ENST00000429701_length(transcript)=1941nt_BP=287nt TCGCGCGGCCGAGAGGCTGCAGCGGCAGCAGCTGTCGCGCCAGTCGCAACAGAAGCAGGTCCGAGGCACAGCCCGATCCCGCCATGGAGC AGCCGAGGAAGGCGGTGGTAGTGACGGGATTTGGCCCTTTTGGGGAACACACCGTGAACGCCAGTTGGATTGCAGTTCAGGAGCTAGAAA AGCTAGGCCTTGGCGACAGCGTGGACCTGCATGTGTACGAGATTCCGGTTGAGTACCAAACAGTCCAGAGACTCATCCCCGCCCTGTGGG AGAAGCACAGTCCACAGGCTCGGCTGGAGCGGGACTTGAGCAACAAGAAAATCTACCAAGAGGAGGAGATGCCCGAATCGGGCGCGGGCA GTGAGTTCAACCGCAAGCTTCGGGAGGAGGCTCGGAGGAAGAAGTACGGCATCGTCCTCAAGGAGTTCCGGCCCGAGGACCAGCCCTGGC TGCTCCGGGTCAACGGCAAATCAGGCAGGAAGAGGAACAAGGTGCTGAACCACTTCAGCATCATGCAGCAGCGGCGGCTCAAGGATCAGG ACCAGGACGAGGATGAGGAGGAGAAGGAGAAACGTGGCCGCAGGAAGGCGAGCGAGCTGCGCATCCACGACCTGGAGGACGACCTGGAGA TGTCGTCCGATGCCAGTGATGCCAGTGGTGAGGAGGGGGGCAGAGTCCCCAAGGCCAAGAAGAAGGCGCCGCTGGCCAAGGGCGGCAGGA AAAAGAAGAAGAAGAAGGGTTCAGACGACGAGGCCTTCGAGGACAGCGATGATGGGGACTTCGAGGGCCAAGAGGTGGACTACATGTCAG ACGGCTCCAGTAGCTCCCAAGAAGAGCCTGAGAGCAAGGCCAAGGCGCCGCAGCAGGAGGAGGGGCCCAAGGGTGTCGATGAGCAGAGCG ACAGTAGTGAGGAGAGTGAGGAGGAGAAGCCGCCTGAGGAGGACAAGGAGGAGGAGGAGGAGAAGAAGGCACCCACCCCGCAGGAGAAGA AGCGCAGGAAAGACAGCAGCGAGGAGTCGGACAGCTCAGAGGAGAGCGACATTGACAGCGAGGCCTCCTCAGCCCTCTTCATGGCGAAGA AGAAGACGCCACCCAAGAGAGAGCGGAAGCCGTCGGGAGGGAGCTCAAGGGGCAACAGCCGCCCAGGCACGCCCAGCGCAGAGGGTGGCA GCACCTCCTCCACCCTGCGGGCGGCTGCCAGCAAACTCGAGCAAGGGAAGCGGGTGAGCGAGATGCCTGCAGCCAAGCGGTTGCGGCTGG ACACGGGACCCCAGAGCCTGTCTGGGAAGTCGACACCCCAGCCACCATCAGGCAAGACAACACCCAACAGCGGCGACGTGCAGGTGACTG AGGATGCCGTGCGCCGCTACCTGACACGGAAGCCCATGACCACTAAGGACCTGCTGAAAAAGTTCCAGACCAAGAAGACAGGGCTGAGCA GCGAGCAGACAGTGAACGTGTTGGCCCAGATCCTCAAGCGACTCAACCCCGAGCGCAAGATGATCAACGACAAAATGCACTTCTCCCTCA AGGAGTGAGGCTTGGTCCAATACATGGCTCTGCCCCCCAGAACTTAAGGCTCTCACTGCCCCTTCGCCATCCTAGAGTGAGGCTCTGTCC AATACATGGCTCTGCCCTCCAGAACTTCAGGCTCTCAGTGACCCTTCGACATCCTGCTTGCTCCCTGACTCCCAGGGCCCCGTAGTTAGC AATTCTGGAAAAGTTAAGCCATCTCCTCCTCTGGCCCTTCCTTCTGGAATCTTCAGATGCCTGTTAGGCCTTCTTATTGTCCTCCTCCTC CTGGCTCGGCCTCCCTCACACTGACCAAGGGCCTGTGCTGCCCACTGGGTAACTTCTACAGTTCTCCCTTCCACTTCCCTAAGTCTCTCT >64649_64649_4_PGPEP1-GTF2F1_PGPEP1_chr19_18466821_ENST00000595066_GTF2F1_chr19_6389648_ENST00000429701_length(amino acids)=484AA_BP=66 MEQPRKAVVVTGFGPFGEHTVNASWIAVQELEKLGLGDSVDLHVYEIPVEYQTVQRLIPALWEKHSPQARLERDLSNKKIYQEEEMPESG AGSEFNRKLREEARRKKYGIVLKEFRPEDQPWLLRVNGKSGRKRNKVLNHFSIMQQRRLKDQDQDEDEEEKEKRGRRKASELRIHDLEDD LEMSSDASDASGEEGGRVPKAKKKAPLAKGGRKKKKKKGSDDEAFEDSDDGDFEGQEVDYMSDGSSSSQEEPESKAKAPQQEEGPKGVDE QSDSSEESEEEKPPEEDKEEEEEKKAPTPQEKKRRKDSSEESDSSEESDIDSEASSALFMAKKKTPPKRERKPSGGSSRGNSRPGTPSAE GGSTSSTLRAAASKLEQGKRVSEMPAAKRLRLDTGPQSLSGKSTPQPPSGKTTPNSGDVQVTEDAVRRYLTRKPMTTKDLLKKFQTKKTG -------------------------------------------------------------- >64649_64649_5_PGPEP1-GTF2F1_PGPEP1_chr19_18466821_ENST00000597431_GTF2F1_chr19_6389648_ENST00000394456_length(transcript)=2381nt_BP=247nt CAGTCGCAACAGAAGCAGGTCCGAGGCACAGCCCGATCCCGCCATGGAGCAGCCGAGGAAGGCGGTGGTAGTGACGGGATTTGGCCCTTT TGGGGAACACACCGTGAACGCCAGTTGGATTGCAGTTCAGGAGCTAGAAAAGCTAGGCCTTGGCGACAGCGTGGACCTGCATGTGTACGA GATTCCGGTTGAGTACCAAACAGTCCAGAGACTCATCCCCGCCCTGTGGGAGAAGCACAGTCCACAGGCTCGGCTGGAGCGGGACTTGAG CAACAAGAAAATCTACCAAGAGGAGGAGATGCCCGAATCGGGCGCGGGCAGTGAGTTCAACCGCAAGCTTCGGGAGGAGGCTCGGAGGAA GAAGTACGGCATCGTCCTCAAGGAGTTCCGGCCCGAGGACCAGCCCTGGCTGCTCCGGGTCAACGGCAAATCAGGCAGGAAGTTCAAGGG CATCAAGAAGGGAGGCGTAACAGAGAACACGTCCTACTACATCTTCACCCAGTGCCCCGACGGGGCCTTCGAGGCCTTCCCCGTGCACAA CTGGTACAATTTCACACCGCTGGCCCGGCATCGCACGCTCACTGCCGAGGAGGCCGAGGAGGAGTGGGAGAGGAGGAACAAGGTGCTGAA CCACTTCAGCATCATGCAGCAGCGGCGGCTCAAGGATCAGGACCAGGACGAGGATGAGGAGGAGAAGGAGAAACGTGGCCGCAGGAAGGC GAGCGAGCTGCGCATCCACGACCTGGAGGACGACCTGGAGATGTCGTCCGATGCCAGTGATGCCAGTGGTGAGGAGGGGGGCAGAGTCCC CAAGGCCAAGAAGAAGGCGCCGCTGGCCAAGGGCGGCAGGAAAAAGAAGAAGAAGAAGGGTTCAGACGACGAGGCCTTCGAGGACAGCGA TGATGGGGACTTCGAGGGCCAAGAGGTGGACTACATGTCAGACGGCTCCAGTAGCTCCCAAGAAGAGCCTGAGAGCAAGGCCAAGGCGCC GCAGCAGGAGGAGGGGCCCAAGGGTGTCGATGAGCAGAGCGACAGTAGTGAGGAGAGTGAGGAGGAGAAGCCGCCTGAGGAGGACAAGGA GGAGGAGGAGGAGAAGAAGGCACCCACCCCGCAGGAGAAGAAGCGCAGGAAAGACAGCAGCGAGGAGTCGGACAGCTCAGAGGAGAGCGA CATTGACAGCGAGGCCTCCTCAGCCCTCTTCATGGCGAAGAAGAAGACGCCACCCAAGAGAGAGCGGAAGCCGTCGGGAGGGAGCTCAAG GGGCAACAGCCGCCCAGGCACGCCCAGCGCAGAGGGTGGCAGCACCTCCTCCACCCTGCGGGCGGCTGCCAGCAAACTCGAGCAAGGGAA GCGGGTGAGCGAGATGCCTGCAGCCAAGCGGTTGCGGCTGGACACGGGACCCCAGAGCCTGTCTGGGAAGTCGACACCCCAGCCACCATC AGGCAAGACAACACCCAACAGCGGCGACGTGCAGGTGACTGAGGATGCCGTGCGCCGCTACCTGACACGGAAGCCCATGACCACTAAGGA CCTGCTGAAAAAGTTCCAGACCAAGAAGACAGGGCTGAGCAGCGAGCAGACAGTGAACGTGTTGGCCCAGATCCTCAAGCGACTCAACCC CGAGCGCAAGATGATCAACGACAAAATGCACTTCTCCCTCAAGGAGTGAGGCTTGGTCCAATACATGGCTCTGCCCCCCAGAACTTAAGG CTCTCACTGCCCCTTCGCCATCCTAGAGTGAGGCTCTGTCCAATACATGGCTCTGCCCTCCAGAACTTCAGGCTCTCAGTGACCCTTCGA CATCCTGCTTGCTCCCTGACTCCCAGGGCCCCGTAGTTAGCAATTCTGGAAAAGTTAAGCCATCTCCTCCTCTGGCCCTTCCTTCTGGAA TCTTCAGATGCCTGTTAGGCCTTCTTATTGTCCTCCTCCTCCTGGCTCGGCCTCCCTCACACTGACCAAGGGCCTGTGCTGCCCACTGGG TAACTTCTACAGTTCTCCCTTCCACTTCCCTAAGTCTCTCTTCAGCTGTGACTTATCCACCACATAGCCCAGTAAGTCTTCAGTTTTGGC TGGGCATGATGGTGAGCGCCTGCAGTCCCAGCTACTTGGGAGGCTAAGCCCAGTTCAAGGCTGCAGTGAACTATGATGGTGCCACTGCAT TCCAGCCTGGGTGACAGAATGAAATCCTGGCACAAAAAAAAAAAAAAAGTAGCCAGGCATGGTGGCGGGAGCCTGTTGTCCCAGCTGTTC CGTAGGCTGAGGCACGAGATTCACTTGAACCTGGGAGGTGGAGGTTGCTGTGAGCTGACACCACGCCACTGCACTCCAGCCTGGGTGACA >64649_64649_5_PGPEP1-GTF2F1_PGPEP1_chr19_18466821_ENST00000597431_GTF2F1_chr19_6389648_ENST00000394456_length(amino acids)=541AA_BP=66 MEQPRKAVVVTGFGPFGEHTVNASWIAVQELEKLGLGDSVDLHVYEIPVEYQTVQRLIPALWEKHSPQARLERDLSNKKIYQEEEMPESG AGSEFNRKLREEARRKKYGIVLKEFRPEDQPWLLRVNGKSGRKFKGIKKGGVTENTSYYIFTQCPDGAFEAFPVHNWYNFTPLARHRTLT AEEAEEEWERRNKVLNHFSIMQQRRLKDQDQDEDEEEKEKRGRRKASELRIHDLEDDLEMSSDASDASGEEGGRVPKAKKKAPLAKGGRK KKKKKGSDDEAFEDSDDGDFEGQEVDYMSDGSSSSQEEPESKAKAPQQEEGPKGVDEQSDSSEESEEEKPPEEDKEEEEEKKAPTPQEKK RRKDSSEESDSSEESDIDSEASSALFMAKKKTPPKRERKPSGGSSRGNSRPGTPSAEGGSTSSTLRAAASKLEQGKRVSEMPAAKRLRLD TGPQSLSGKSTPQPPSGKTTPNSGDVQVTEDAVRRYLTRKPMTTKDLLKKFQTKKTGLSSEQTVNVLAQILKRLNPERKMINDKMHFSLK -------------------------------------------------------------- >64649_64649_6_PGPEP1-GTF2F1_PGPEP1_chr19_18466821_ENST00000597431_GTF2F1_chr19_6389648_ENST00000429701_length(transcript)=1901nt_BP=247nt CAGTCGCAACAGAAGCAGGTCCGAGGCACAGCCCGATCCCGCCATGGAGCAGCCGAGGAAGGCGGTGGTAGTGACGGGATTTGGCCCTTT TGGGGAACACACCGTGAACGCCAGTTGGATTGCAGTTCAGGAGCTAGAAAAGCTAGGCCTTGGCGACAGCGTGGACCTGCATGTGTACGA GATTCCGGTTGAGTACCAAACAGTCCAGAGACTCATCCCCGCCCTGTGGGAGAAGCACAGTCCACAGGCTCGGCTGGAGCGGGACTTGAG CAACAAGAAAATCTACCAAGAGGAGGAGATGCCCGAATCGGGCGCGGGCAGTGAGTTCAACCGCAAGCTTCGGGAGGAGGCTCGGAGGAA GAAGTACGGCATCGTCCTCAAGGAGTTCCGGCCCGAGGACCAGCCCTGGCTGCTCCGGGTCAACGGCAAATCAGGCAGGAAGAGGAACAA GGTGCTGAACCACTTCAGCATCATGCAGCAGCGGCGGCTCAAGGATCAGGACCAGGACGAGGATGAGGAGGAGAAGGAGAAACGTGGCCG CAGGAAGGCGAGCGAGCTGCGCATCCACGACCTGGAGGACGACCTGGAGATGTCGTCCGATGCCAGTGATGCCAGTGGTGAGGAGGGGGG CAGAGTCCCCAAGGCCAAGAAGAAGGCGCCGCTGGCCAAGGGCGGCAGGAAAAAGAAGAAGAAGAAGGGTTCAGACGACGAGGCCTTCGA GGACAGCGATGATGGGGACTTCGAGGGCCAAGAGGTGGACTACATGTCAGACGGCTCCAGTAGCTCCCAAGAAGAGCCTGAGAGCAAGGC CAAGGCGCCGCAGCAGGAGGAGGGGCCCAAGGGTGTCGATGAGCAGAGCGACAGTAGTGAGGAGAGTGAGGAGGAGAAGCCGCCTGAGGA GGACAAGGAGGAGGAGGAGGAGAAGAAGGCACCCACCCCGCAGGAGAAGAAGCGCAGGAAAGACAGCAGCGAGGAGTCGGACAGCTCAGA GGAGAGCGACATTGACAGCGAGGCCTCCTCAGCCCTCTTCATGGCGAAGAAGAAGACGCCACCCAAGAGAGAGCGGAAGCCGTCGGGAGG GAGCTCAAGGGGCAACAGCCGCCCAGGCACGCCCAGCGCAGAGGGTGGCAGCACCTCCTCCACCCTGCGGGCGGCTGCCAGCAAACTCGA GCAAGGGAAGCGGGTGAGCGAGATGCCTGCAGCCAAGCGGTTGCGGCTGGACACGGGACCCCAGAGCCTGTCTGGGAAGTCGACACCCCA GCCACCATCAGGCAAGACAACACCCAACAGCGGCGACGTGCAGGTGACTGAGGATGCCGTGCGCCGCTACCTGACACGGAAGCCCATGAC CACTAAGGACCTGCTGAAAAAGTTCCAGACCAAGAAGACAGGGCTGAGCAGCGAGCAGACAGTGAACGTGTTGGCCCAGATCCTCAAGCG ACTCAACCCCGAGCGCAAGATGATCAACGACAAAATGCACTTCTCCCTCAAGGAGTGAGGCTTGGTCCAATACATGGCTCTGCCCCCCAG AACTTAAGGCTCTCACTGCCCCTTCGCCATCCTAGAGTGAGGCTCTGTCCAATACATGGCTCTGCCCTCCAGAACTTCAGGCTCTCAGTG ACCCTTCGACATCCTGCTTGCTCCCTGACTCCCAGGGCCCCGTAGTTAGCAATTCTGGAAAAGTTAAGCCATCTCCTCCTCTGGCCCTTC CTTCTGGAATCTTCAGATGCCTGTTAGGCCTTCTTATTGTCCTCCTCCTCCTGGCTCGGCCTCCCTCACACTGACCAAGGGCCTGTGCTG CCCACTGGGTAACTTCTACAGTTCTCCCTTCCACTTCCCTAAGTCTCTCTTCAGCTGTGACTTATCCACCACATAGCCCAGTAAGTCTTC >64649_64649_6_PGPEP1-GTF2F1_PGPEP1_chr19_18466821_ENST00000597431_GTF2F1_chr19_6389648_ENST00000429701_length(amino acids)=484AA_BP=66 MEQPRKAVVVTGFGPFGEHTVNASWIAVQELEKLGLGDSVDLHVYEIPVEYQTVQRLIPALWEKHSPQARLERDLSNKKIYQEEEMPESG AGSEFNRKLREEARRKKYGIVLKEFRPEDQPWLLRVNGKSGRKRNKVLNHFSIMQQRRLKDQDQDEDEEEKEKRGRRKASELRIHDLEDD LEMSSDASDASGEEGGRVPKAKKKAPLAKGGRKKKKKKGSDDEAFEDSDDGDFEGQEVDYMSDGSSSSQEEPESKAKAPQQEEGPKGVDE QSDSSEESEEEKPPEEDKEEEEEKKAPTPQEKKRRKDSSEESDSSEESDIDSEASSALFMAKKKTPPKRERKPSGGSSRGNSRPGTPSAE GGSTSSTLRAAASKLEQGKRVSEMPAAKRLRLDTGPQSLSGKSTPQPPSGKTTPNSGDVQVTEDAVRRYLTRKPMTTKDLLKKFQTKKTG -------------------------------------------------------------- >64649_64649_7_PGPEP1-GTF2F1_PGPEP1_chr19_18466821_ENST00000604499_GTF2F1_chr19_6389648_ENST00000394456_length(transcript)=2422nt_BP=288nt CTCGCGCGGCCGAGAGGCTGCAGCGGCAGCAGCTGTCGCGCCAGTCGCAACAGAAGCAGGTCCGAGGCACAGCCCGATCCCGCCATGGAG CAGCCGAGGAAGGCGGTGGTAGTGACGGGATTTGGCCCTTTTGGGGAACACACCGTGAACGCCAGTTGGATTGCAGTTCAGGAGCTAGAA AAGCTAGGCCTTGGCGACAGCGTGGACCTGCATGTGTACGAGATTCCGGTTGAGTACCAAACAGTCCAGAGACTCATCCCCGCCCTGTGG GAGAAGCACAGTCCACAGGCTCGGCTGGAGCGGGACTTGAGCAACAAGAAAATCTACCAAGAGGAGGAGATGCCCGAATCGGGCGCGGGC AGTGAGTTCAACCGCAAGCTTCGGGAGGAGGCTCGGAGGAAGAAGTACGGCATCGTCCTCAAGGAGTTCCGGCCCGAGGACCAGCCCTGG CTGCTCCGGGTCAACGGCAAATCAGGCAGGAAGTTCAAGGGCATCAAGAAGGGAGGCGTAACAGAGAACACGTCCTACTACATCTTCACC CAGTGCCCCGACGGGGCCTTCGAGGCCTTCCCCGTGCACAACTGGTACAATTTCACACCGCTGGCCCGGCATCGCACGCTCACTGCCGAG GAGGCCGAGGAGGAGTGGGAGAGGAGGAACAAGGTGCTGAACCACTTCAGCATCATGCAGCAGCGGCGGCTCAAGGATCAGGACCAGGAC GAGGATGAGGAGGAGAAGGAGAAACGTGGCCGCAGGAAGGCGAGCGAGCTGCGCATCCACGACCTGGAGGACGACCTGGAGATGTCGTCC GATGCCAGTGATGCCAGTGGTGAGGAGGGGGGCAGAGTCCCCAAGGCCAAGAAGAAGGCGCCGCTGGCCAAGGGCGGCAGGAAAAAGAAG AAGAAGAAGGGTTCAGACGACGAGGCCTTCGAGGACAGCGATGATGGGGACTTCGAGGGCCAAGAGGTGGACTACATGTCAGACGGCTCC AGTAGCTCCCAAGAAGAGCCTGAGAGCAAGGCCAAGGCGCCGCAGCAGGAGGAGGGGCCCAAGGGTGTCGATGAGCAGAGCGACAGTAGT GAGGAGAGTGAGGAGGAGAAGCCGCCTGAGGAGGACAAGGAGGAGGAGGAGGAGAAGAAGGCACCCACCCCGCAGGAGAAGAAGCGCAGG AAAGACAGCAGCGAGGAGTCGGACAGCTCAGAGGAGAGCGACATTGACAGCGAGGCCTCCTCAGCCCTCTTCATGGCGAAGAAGAAGACG CCACCCAAGAGAGAGCGGAAGCCGTCGGGAGGGAGCTCAAGGGGCAACAGCCGCCCAGGCACGCCCAGCGCAGAGGGTGGCAGCACCTCC TCCACCCTGCGGGCGGCTGCCAGCAAACTCGAGCAAGGGAAGCGGGTGAGCGAGATGCCTGCAGCCAAGCGGTTGCGGCTGGACACGGGA CCCCAGAGCCTGTCTGGGAAGTCGACACCCCAGCCACCATCAGGCAAGACAACACCCAACAGCGGCGACGTGCAGGTGACTGAGGATGCC GTGCGCCGCTACCTGACACGGAAGCCCATGACCACTAAGGACCTGCTGAAAAAGTTCCAGACCAAGAAGACAGGGCTGAGCAGCGAGCAG ACAGTGAACGTGTTGGCCCAGATCCTCAAGCGACTCAACCCCGAGCGCAAGATGATCAACGACAAAATGCACTTCTCCCTCAAGGAGTGA GGCTTGGTCCAATACATGGCTCTGCCCCCCAGAACTTAAGGCTCTCACTGCCCCTTCGCCATCCTAGAGTGAGGCTCTGTCCAATACATG GCTCTGCCCTCCAGAACTTCAGGCTCTCAGTGACCCTTCGACATCCTGCTTGCTCCCTGACTCCCAGGGCCCCGTAGTTAGCAATTCTGG AAAAGTTAAGCCATCTCCTCCTCTGGCCCTTCCTTCTGGAATCTTCAGATGCCTGTTAGGCCTTCTTATTGTCCTCCTCCTCCTGGCTCG GCCTCCCTCACACTGACCAAGGGCCTGTGCTGCCCACTGGGTAACTTCTACAGTTCTCCCTTCCACTTCCCTAAGTCTCTCTTCAGCTGT GACTTATCCACCACATAGCCCAGTAAGTCTTCAGTTTTGGCTGGGCATGATGGTGAGCGCCTGCAGTCCCAGCTACTTGGGAGGCTAAGC CCAGTTCAAGGCTGCAGTGAACTATGATGGTGCCACTGCATTCCAGCCTGGGTGACAGAATGAAATCCTGGCACAAAAAAAAAAAAAAAG TAGCCAGGCATGGTGGCGGGAGCCTGTTGTCCCAGCTGTTCCGTAGGCTGAGGCACGAGATTCACTTGAACCTGGGAGGTGGAGGTTGCT >64649_64649_7_PGPEP1-GTF2F1_PGPEP1_chr19_18466821_ENST00000604499_GTF2F1_chr19_6389648_ENST00000394456_length(amino acids)=541AA_BP=66 MEQPRKAVVVTGFGPFGEHTVNASWIAVQELEKLGLGDSVDLHVYEIPVEYQTVQRLIPALWEKHSPQARLERDLSNKKIYQEEEMPESG AGSEFNRKLREEARRKKYGIVLKEFRPEDQPWLLRVNGKSGRKFKGIKKGGVTENTSYYIFTQCPDGAFEAFPVHNWYNFTPLARHRTLT AEEAEEEWERRNKVLNHFSIMQQRRLKDQDQDEDEEEKEKRGRRKASELRIHDLEDDLEMSSDASDASGEEGGRVPKAKKKAPLAKGGRK KKKKKGSDDEAFEDSDDGDFEGQEVDYMSDGSSSSQEEPESKAKAPQQEEGPKGVDEQSDSSEESEEEKPPEEDKEEEEEKKAPTPQEKK RRKDSSEESDSSEESDIDSEASSALFMAKKKTPPKRERKPSGGSSRGNSRPGTPSAEGGSTSSTLRAAASKLEQGKRVSEMPAAKRLRLD TGPQSLSGKSTPQPPSGKTTPNSGDVQVTEDAVRRYLTRKPMTTKDLLKKFQTKKTGLSSEQTVNVLAQILKRLNPERKMINDKMHFSLK -------------------------------------------------------------- >64649_64649_8_PGPEP1-GTF2F1_PGPEP1_chr19_18466821_ENST00000604499_GTF2F1_chr19_6389648_ENST00000429701_length(transcript)=1942nt_BP=288nt CTCGCGCGGCCGAGAGGCTGCAGCGGCAGCAGCTGTCGCGCCAGTCGCAACAGAAGCAGGTCCGAGGCACAGCCCGATCCCGCCATGGAG CAGCCGAGGAAGGCGGTGGTAGTGACGGGATTTGGCCCTTTTGGGGAACACACCGTGAACGCCAGTTGGATTGCAGTTCAGGAGCTAGAA AAGCTAGGCCTTGGCGACAGCGTGGACCTGCATGTGTACGAGATTCCGGTTGAGTACCAAACAGTCCAGAGACTCATCCCCGCCCTGTGG GAGAAGCACAGTCCACAGGCTCGGCTGGAGCGGGACTTGAGCAACAAGAAAATCTACCAAGAGGAGGAGATGCCCGAATCGGGCGCGGGC AGTGAGTTCAACCGCAAGCTTCGGGAGGAGGCTCGGAGGAAGAAGTACGGCATCGTCCTCAAGGAGTTCCGGCCCGAGGACCAGCCCTGG CTGCTCCGGGTCAACGGCAAATCAGGCAGGAAGAGGAACAAGGTGCTGAACCACTTCAGCATCATGCAGCAGCGGCGGCTCAAGGATCAG GACCAGGACGAGGATGAGGAGGAGAAGGAGAAACGTGGCCGCAGGAAGGCGAGCGAGCTGCGCATCCACGACCTGGAGGACGACCTGGAG ATGTCGTCCGATGCCAGTGATGCCAGTGGTGAGGAGGGGGGCAGAGTCCCCAAGGCCAAGAAGAAGGCGCCGCTGGCCAAGGGCGGCAGG AAAAAGAAGAAGAAGAAGGGTTCAGACGACGAGGCCTTCGAGGACAGCGATGATGGGGACTTCGAGGGCCAAGAGGTGGACTACATGTCA GACGGCTCCAGTAGCTCCCAAGAAGAGCCTGAGAGCAAGGCCAAGGCGCCGCAGCAGGAGGAGGGGCCCAAGGGTGTCGATGAGCAGAGC GACAGTAGTGAGGAGAGTGAGGAGGAGAAGCCGCCTGAGGAGGACAAGGAGGAGGAGGAGGAGAAGAAGGCACCCACCCCGCAGGAGAAG AAGCGCAGGAAAGACAGCAGCGAGGAGTCGGACAGCTCAGAGGAGAGCGACATTGACAGCGAGGCCTCCTCAGCCCTCTTCATGGCGAAG AAGAAGACGCCACCCAAGAGAGAGCGGAAGCCGTCGGGAGGGAGCTCAAGGGGCAACAGCCGCCCAGGCACGCCCAGCGCAGAGGGTGGC AGCACCTCCTCCACCCTGCGGGCGGCTGCCAGCAAACTCGAGCAAGGGAAGCGGGTGAGCGAGATGCCTGCAGCCAAGCGGTTGCGGCTG GACACGGGACCCCAGAGCCTGTCTGGGAAGTCGACACCCCAGCCACCATCAGGCAAGACAACACCCAACAGCGGCGACGTGCAGGTGACT GAGGATGCCGTGCGCCGCTACCTGACACGGAAGCCCATGACCACTAAGGACCTGCTGAAAAAGTTCCAGACCAAGAAGACAGGGCTGAGC AGCGAGCAGACAGTGAACGTGTTGGCCCAGATCCTCAAGCGACTCAACCCCGAGCGCAAGATGATCAACGACAAAATGCACTTCTCCCTC AAGGAGTGAGGCTTGGTCCAATACATGGCTCTGCCCCCCAGAACTTAAGGCTCTCACTGCCCCTTCGCCATCCTAGAGTGAGGCTCTGTC CAATACATGGCTCTGCCCTCCAGAACTTCAGGCTCTCAGTGACCCTTCGACATCCTGCTTGCTCCCTGACTCCCAGGGCCCCGTAGTTAG CAATTCTGGAAAAGTTAAGCCATCTCCTCCTCTGGCCCTTCCTTCTGGAATCTTCAGATGCCTGTTAGGCCTTCTTATTGTCCTCCTCCT CCTGGCTCGGCCTCCCTCACACTGACCAAGGGCCTGTGCTGCCCACTGGGTAACTTCTACAGTTCTCCCTTCCACTTCCCTAAGTCTCTC >64649_64649_8_PGPEP1-GTF2F1_PGPEP1_chr19_18466821_ENST00000604499_GTF2F1_chr19_6389648_ENST00000429701_length(amino acids)=484AA_BP=66 MEQPRKAVVVTGFGPFGEHTVNASWIAVQELEKLGLGDSVDLHVYEIPVEYQTVQRLIPALWEKHSPQARLERDLSNKKIYQEEEMPESG AGSEFNRKLREEARRKKYGIVLKEFRPEDQPWLLRVNGKSGRKRNKVLNHFSIMQQRRLKDQDQDEDEEEKEKRGRRKASELRIHDLEDD LEMSSDASDASGEEGGRVPKAKKKAPLAKGGRKKKKKKGSDDEAFEDSDDGDFEGQEVDYMSDGSSSSQEEPESKAKAPQQEEGPKGVDE QSDSSEESEEEKPPEEDKEEEEEKKAPTPQEKKRRKDSSEESDSSEESDIDSEASSALFMAKKKTPPKRERKPSGGSSRGNSRPGTPSAE GGSTSSTLRAAASKLEQGKRVSEMPAAKRLRLDTGPQSLSGKSTPQPPSGKTTPNSGDVQVTEDAVRRYLTRKPMTTKDLLKKFQTKKTG -------------------------------------------------------------- |
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Fusion Gene PPI Analysis for PGPEP1-GTF2F1 |
| Go to ChiPPI (Chimeric Protein-Protein interactions) to see the chimeric PPI interaction in |
| Protein-protein interactors with each fusion partner protein in wild-type (BIOGRID-3.4.160) |
| Hgene | Hgene's interactors | Tgene | Tgene's interactors |
| - Retained PPIs in in-frame fusion. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Still interaction with |
| - Lost PPIs in in-frame fusion. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Interaction lost with |
| - Retained PPIs, but lost function due to frame-shift fusion. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Interaction lost with |
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Related Drugs for PGPEP1-GTF2F1 |
| Drugs targeting genes involved in this fusion gene. (DrugBank Version 5.1.8 2021-05-08) |
| Partner | Gene | UniProtAcc | DrugBank ID | Drug name | Drug activity | Drug type | Drug status |
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Related Diseases for PGPEP1-GTF2F1 |
| Diseases associated with fusion partners. (DisGeNet 4.0) |
| Partner | Gene | Disease ID | Disease name | # pubmeds | Source |
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