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Center for Computational Systems Medicine
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Fusion Gene Summary

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Fusion Gene ORF analysis

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Fusion Genomic Features

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Fusion Protein Features

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Fusion Gene Sequence

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Fusion Gene PPI analysis

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Related Drugs

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Related Diseases

Fusion gene:PGS1-BPTF (FusionGDB2 ID:64664)

Fusion Gene Summary for PGS1-BPTF

check button Fusion gene summary
Fusion gene informationFusion gene name: PGS1-BPTF
Fusion gene ID: 64664
HgeneTgene
Gene symbol

PGS1

BPTF

Gene ID

9489

2186

Gene namephosphatidylglycerophosphate synthase 1bromodomain PHD finger transcription factor
Synonyms-FAC1|FALZ|NEDDFL|NURF301
Cytomap

17q25.3

17q24.2

Type of geneprotein-codingprotein-coding
DescriptionCDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase, mitochondrialPGP synthase 1nucleosome-remodeling factor subunit BPTFbromodomain and PHD domain transcription factorbromodomain and PHD finger-containing transcription factorfetal Alz-50 clone 1 proteinfetal Alz-50 reactive clone 1fetal Alzheimer antigennucleosome remodeling f
Modification date2020031320200313
UniProtAcc.

Q12830

Ensembl transtripts involved in fusion geneENST00000588281, ENST00000262764, 
ENST00000329897, 		ENST00000306378, 
ENST00000321892, ENST00000335221, 
ENST00000424123, ENST00000577770, 
Fusion gene scores* DoF score11 X 9 X 6=59423 X 23 X 6=3174
# samples 1426
** MAII scorelog2(14/594*10)=-2.0850361038558
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0		log2(26/3174*10)=-3.60971859980673
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0
Context

PubMed: PGS1 [Title/Abstract] AND BPTF [Title/Abstract] AND fusion [Title/Abstract]

Most frequent breakpointPGS1(76400170)-BPTF(65916131), # samples:3
Anticipated loss of major functional domain due to fusion event.
* DoF score (Degree of Frequency) = # partners X # break points X # cancer types
** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10)

check button Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez
PartnerGeneGO IDGO termPubMed ID
TgeneBPTF

GO:0000122

negative regulation of transcription by RNA polymerase II

10727212

TgeneBPTF

GO:0006338

chromatin remodeling

14609955


check buttonFusion gene breakpoints across PGS1 (5'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.
all structure

check buttonFusion gene breakpoints across BPTF (3'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.
all structure

check button Fusion gene information from two resources (ChiTars 5.0 and ChimerDB 4.0)
* All genome coordinats were lifted-over on hg19.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
SourceDiseaseSampleHgeneHchrHbpHstrandTgeneTchrTbpTstrand
ChimerDB4ESCATCGA-L5-A4OW-01APGS1chr17

76400170

-BPTFchr17

65916131

+
ChimerDB4ESCATCGA-L5-A4OW-01APGS1chr17

76400170

+BPTFchr17

65916131

+
ChimerDB4ESCATCGA-L5-A4OWPGS1chr17

76400170

+BPTFchr17

65916130

+
ChimerDB4ESCATCGA-L5-A4OWPGS1chr17

76400170

+BPTFchr17

65916131

+


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Fusion Gene ORF analysis for PGS1-BPTF

check button Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
ORFHenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrand
3UTR-3CDSENST00000588281ENST00000306378PGS1chr17

76400170

+BPTFchr17

65916131

+
3UTR-3CDSENST00000588281ENST00000306378PGS1chr17

76400170

+BPTFchr17

65916130

+
3UTR-3CDSENST00000588281ENST00000321892PGS1chr17

76400170

+BPTFchr17

65916131

+
3UTR-3CDSENST00000588281ENST00000321892PGS1chr17

76400170

+BPTFchr17

65916130

+
3UTR-3CDSENST00000588281ENST00000335221PGS1chr17

76400170

+BPTFchr17

65916131

+
3UTR-3CDSENST00000588281ENST00000335221PGS1chr17

76400170

+BPTFchr17

65916130

+
3UTR-3CDSENST00000588281ENST00000424123PGS1chr17

76400170

+BPTFchr17

65916131

+
3UTR-3CDSENST00000588281ENST00000424123PGS1chr17

76400170

+BPTFchr17

65916130

+
3UTR-intronENST00000588281ENST00000577770PGS1chr17

76400170

+BPTFchr17

65916131

+
3UTR-intronENST00000588281ENST00000577770PGS1chr17

76400170

+BPTFchr17

65916130

+
5CDS-intronENST00000262764ENST00000577770PGS1chr17

76400170

+BPTFchr17

65916131

+
5CDS-intronENST00000262764ENST00000577770PGS1chr17

76400170

+BPTFchr17

65916130

+
5CDS-intronENST00000329897ENST00000577770PGS1chr17

76400170

+BPTFchr17

65916131

+
5CDS-intronENST00000329897ENST00000577770PGS1chr17

76400170

+BPTFchr17

65916130

+
In-frameENST00000262764ENST00000306378PGS1chr17

76400170

+BPTFchr17

65916131

+
In-frameENST00000262764ENST00000306378PGS1chr17

76400170

+BPTFchr17

65916130

+
In-frameENST00000262764ENST00000321892PGS1chr17

76400170

+BPTFchr17

65916131

+
In-frameENST00000262764ENST00000321892PGS1chr17

76400170

+BPTFchr17

65916130

+
In-frameENST00000262764ENST00000335221PGS1chr17

76400170

+BPTFchr17

65916131

+
In-frameENST00000262764ENST00000335221PGS1chr17

76400170

+BPTFchr17

65916130

+
In-frameENST00000262764ENST00000424123PGS1chr17

76400170

+BPTFchr17

65916131

+
In-frameENST00000262764ENST00000424123PGS1chr17

76400170

+BPTFchr17

65916130

+
In-frameENST00000329897ENST00000306378PGS1chr17

76400170

+BPTFchr17

65916131

+
In-frameENST00000329897ENST00000306378PGS1chr17

76400170

+BPTFchr17

65916130

+
In-frameENST00000329897ENST00000321892PGS1chr17

76400170

+BPTFchr17

65916131

+
In-frameENST00000329897ENST00000321892PGS1chr17

76400170

+BPTFchr17

65916130

+
In-frameENST00000329897ENST00000335221PGS1chr17

76400170

+BPTFchr17

65916131

+
In-frameENST00000329897ENST00000335221PGS1chr17

76400170

+BPTFchr17

65916130

+
In-frameENST00000329897ENST00000424123PGS1chr17

76400170

+BPTFchr17

65916131

+
In-frameENST00000329897ENST00000424123PGS1chr17

76400170

+BPTFchr17

65916130

+

check buttonORFfinder result based on the fusion transcript sequence of in-frame fusion genes.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandSeq length
(transcript)		BP loci
(transcript)		Predicted start
(transcript)		Predicted stop
(transcript)		Seq length
(amino acids)
ENST00000262764PGS1chr1776400170+ENST00000335221BPTFchr1765916131+642414282643331435
ENST00000262764PGS1chr1776400170+ENST00000321892BPTFchr1765916131+685314282647621578
ENST00000262764PGS1chr1776400170+ENST00000306378BPTFchr1765916131+562814282647621578
ENST00000262764PGS1chr1776400170+ENST00000424123BPTFchr1765916131+433414282643331436
ENST00000329897PGS1chr1776400170+ENST00000335221BPTFchr1765916131+628612902341951390
ENST00000329897PGS1chr1776400170+ENST00000321892BPTFchr1765916131+671512902346241533
ENST00000329897PGS1chr1776400170+ENST00000306378BPTFchr1765916131+549012902346241533
ENST00000329897PGS1chr1776400170+ENST00000424123BPTFchr1765916131+419612902341951391
ENST00000262764PGS1chr1776400170+ENST00000335221BPTFchr1765916130+642414282643331435
ENST00000262764PGS1chr1776400170+ENST00000321892BPTFchr1765916130+685314282647621578
ENST00000262764PGS1chr1776400170+ENST00000306378BPTFchr1765916130+562814282647621578
ENST00000262764PGS1chr1776400170+ENST00000424123BPTFchr1765916130+433414282643331436
ENST00000329897PGS1chr1776400170+ENST00000335221BPTFchr1765916130+628612902341951390
ENST00000329897PGS1chr1776400170+ENST00000321892BPTFchr1765916130+671512902346241533
ENST00000329897PGS1chr1776400170+ENST00000306378BPTFchr1765916130+549012902346241533
ENST00000329897PGS1chr1776400170+ENST00000424123BPTFchr1765916130+419612902341951391

check buttonDeepORF prediction of the coding potential based on the fusion transcript sequence of in-frame fusion genes. DeepORF is a coding potential classifier based on convolutional neural network by comparing the real Ribo-seq data. If the no-coding score < 0.5 and coding score > 0.5, then the in-frame fusion transcript is predicted as being likely translated.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandNo-coding scoreCoding score
ENST00000262764ENST00000335221PGS1chr1776400170+BPTFchr1765916131+0.0003599590.99964
ENST00000262764ENST00000321892PGS1chr1776400170+BPTFchr1765916131+0.000624450.9993755
ENST00000262764ENST00000306378PGS1chr1776400170+BPTFchr1765916131+0.0013860250.99861395
ENST00000262764ENST00000424123PGS1chr1776400170+BPTFchr1765916131+0.0018002150.9981997
ENST00000329897ENST00000335221PGS1chr1776400170+BPTFchr1765916131+0.0004435620.99955636
ENST00000329897ENST00000321892PGS1chr1776400170+BPTFchr1765916131+0.0008084970.99919146
ENST00000329897ENST00000306378PGS1chr1776400170+BPTFchr1765916131+0.0018176530.9981824
ENST00000329897ENST00000424123PGS1chr1776400170+BPTFchr1765916131+0.0023338660.9976661
ENST00000262764ENST00000335221PGS1chr1776400170+BPTFchr1765916130+0.0003599590.99964
ENST00000262764ENST00000321892PGS1chr1776400170+BPTFchr1765916130+0.000624450.9993755
ENST00000262764ENST00000306378PGS1chr1776400170+BPTFchr1765916130+0.0013860250.99861395
ENST00000262764ENST00000424123PGS1chr1776400170+BPTFchr1765916130+0.0018002150.9981997
ENST00000329897ENST00000335221PGS1chr1776400170+BPTFchr1765916130+0.0004435620.99955636
ENST00000329897ENST00000321892PGS1chr1776400170+BPTFchr1765916130+0.0008084970.99919146
ENST00000329897ENST00000306378PGS1chr1776400170+BPTFchr1765916130+0.0018176530.9981824
ENST00000329897ENST00000424123PGS1chr1776400170+BPTFchr1765916130+0.0023338660.9976661

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Fusion Genomic Features for PGS1-BPTF


check buttonFusionAI prediction of the potential fusion gene breakpoint based on the pre-mature RNA sequence context (+/- 5kb of individual partner genes, total 20kb length sequence). FusionAI is a fusion gene breakpoint classifier based on convolutional neural network by comparing the fusion positive and negative sequence context of ~ 20K fusion gene data. From here, we can have the relative potentency of the 20K genomic sequence how individual sequnce will be likely used as the gene fusion breakpoints.
HgeneHchrHbpHstrandTgeneTchrTbpTstrand1-pp (fusion gene breakpoint)
PGS1chr1776400170+BPTFchr1765916130+4.47E-070.9999995
PGS1chr1776400170+BPTFchr1765916130+4.47E-070.9999995
PGS1chr1776400170+BPTFchr1765916130+4.47E-070.9999995
PGS1chr1776400170+BPTFchr1765916130+4.47E-070.9999995

check buttonDistribution of 44 human genomic features loci across 20kb length fusion breakpoint regions. We integrated a total of 44 different types of human genomic feature loci information across five big categories including virus integration sites, repeats, structural variants, chromatin states, and gene expression regulation. More details are in help page.
genomic feature

check buttonDistribution of 44 human genomic features loci across 20kb length fusion breakpoint regions that are ovelapped with the top 1% feature importance score regions. More details are in help page.
genomic feature of top 1%

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Fusion Protein Features for PGS1-BPTF


check button Four levels of functional features of fusion genes
Go to FGviewer search page for the most frequent breakpoint (https://ccsmweb.uth.edu/FGviewer/chr17:76400170/chr17:65916131)
- FGviewer provides the online visualization of the retention search of the protein functional features across DNA, RNA, protein, and pathological levels.
- How to search
1. Put your fusion gene symbol.
2. Press the tab key until there will be shown the breakpoint information filled.
4. Go down and press 'Search' tab twice.
4. Go down to have the hyperlink of the search result.
5. Click the hyperlink.
6. See the FGviewer result for your fusion gene.
FGviewer

check buttonMain function of each fusion partner protein. (from UniProt)
HgeneTgene
.BPTF

Q12830

FUNCTION: Transcriptional activator which is required for calcium-dependent dendritic growth and branching in cortical neurons. Recruits CREB-binding protein (CREBBP) to nuclear bodies. Component of the CREST-BRG1 complex, a multiprotein complex that regulates promoter activation by orchestrating a calcium-dependent release of a repressor complex and a recruitment of an activator complex. In resting neurons, transcription of the c-FOS promoter is inhibited by BRG1-dependent recruitment of a phospho-RB1-HDAC1 repressor complex. Upon calcium influx, RB1 is dephosphorylated by calcineurin, which leads to release of the repressor complex. At the same time, there is increased recruitment of CREBBP to the promoter by a CREST-dependent mechanism, which leads to transcriptional activation. The CREST-BRG1 complex also binds to the NR2B promoter, and activity-dependent induction of NR2B expression involves a release of HDAC1 and recruitment of CREBBP (By similarity). {ECO:0000250}.FUNCTION: Histone-binding component of NURF (nucleosome-remodeling factor), a complex which catalyzes ATP-dependent nucleosome sliding and facilitates transcription of chromatin. Specifically recognizes H3 tails trimethylated on 'Lys-4' (H3K4me3), which mark transcription start sites of virtually all active genes. May also regulate transcription through direct binding to DNA or transcription factors.

check buttonRetention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at

download page


* Minus value of BPloci means that the break pointn is located before the CDS.
- In-frame and retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
HgenePGS1chr17:76400170chr17:65916130ENST00000262764+710215_241467665.3333333333334DomainPLD phosphodiesterase 1
HgenePGS1chr17:76400170chr17:65916131ENST00000262764+710215_241467665.3333333333334DomainPLD phosphodiesterase 1
HgenePGS1chr17:76400170chr17:65916130ENST00000262764+710124_131467665.3333333333334Nucleotide bindingATP
HgenePGS1chr17:76400170chr17:65916131ENST00000262764+710124_131467665.3333333333334Nucleotide bindingATP
TgeneBPTFchr17:76400170chr17:65916130ENST0000030637811282022_205018092921.0Coiled coilOntology_term=ECO:0000255
TgeneBPTFchr17:76400170chr17:65916130ENST0000030637811282706_273218092921.0Coiled coilOntology_term=ECO:0000255
TgeneBPTFchr17:76400170chr17:65916130ENST0000032189213302022_205019353047.0Coiled coilOntology_term=ECO:0000255
TgeneBPTFchr17:76400170chr17:65916130ENST0000032189213302706_273219353047.0Coiled coilOntology_term=ECO:0000255
TgeneBPTFchr17:76400170chr17:65916130ENST0000033522113302022_205019352904.0Coiled coilOntology_term=ECO:0000255
TgeneBPTFchr17:76400170chr17:65916130ENST0000033522113302706_273219352904.0Coiled coilOntology_term=ECO:0000255
TgeneBPTFchr17:76400170chr17:65916131ENST0000030637811282022_205018092921.0Coiled coilOntology_term=ECO:0000255
TgeneBPTFchr17:76400170chr17:65916131ENST0000030637811282706_273218092921.0Coiled coilOntology_term=ECO:0000255
TgeneBPTFchr17:76400170chr17:65916131ENST0000032189213302022_205019353047.0Coiled coilOntology_term=ECO:0000255
TgeneBPTFchr17:76400170chr17:65916131ENST0000032189213302706_273219353047.0Coiled coilOntology_term=ECO:0000255
TgeneBPTFchr17:76400170chr17:65916131ENST0000033522113302022_205019352904.0Coiled coilOntology_term=ECO:0000255
TgeneBPTFchr17:76400170chr17:65916131ENST0000033522113302706_273219352904.0Coiled coilOntology_term=ECO:0000255
TgeneBPTFchr17:76400170chr17:65916130ENST0000030637811282338_236118092921.0Compositional biasNote=Thr-rich
TgeneBPTFchr17:76400170chr17:65916130ENST0000030637811282795_281718092921.0Compositional biasNote=Pro-rich
TgeneBPTFchr17:76400170chr17:65916130ENST0000030637811282848_285318092921.0Compositional biasNote=Poly-Lys
TgeneBPTFchr17:76400170chr17:65916130ENST0000032189213302338_236119353047.0Compositional biasNote=Thr-rich
TgeneBPTFchr17:76400170chr17:65916130ENST0000032189213302795_281719353047.0Compositional biasNote=Pro-rich
TgeneBPTFchr17:76400170chr17:65916130ENST0000032189213302848_285319353047.0Compositional biasNote=Poly-Lys
TgeneBPTFchr17:76400170chr17:65916130ENST0000033522113302338_236119352904.0Compositional biasNote=Thr-rich
TgeneBPTFchr17:76400170chr17:65916130ENST0000033522113302795_281719352904.0Compositional biasNote=Pro-rich
TgeneBPTFchr17:76400170chr17:65916130ENST0000033522113302848_285319352904.0Compositional biasNote=Poly-Lys
TgeneBPTFchr17:76400170chr17:65916131ENST0000030637811282338_236118092921.0Compositional biasNote=Thr-rich
TgeneBPTFchr17:76400170chr17:65916131ENST0000030637811282795_281718092921.0Compositional biasNote=Pro-rich
TgeneBPTFchr17:76400170chr17:65916131ENST0000030637811282848_285318092921.0Compositional biasNote=Poly-Lys
TgeneBPTFchr17:76400170chr17:65916131ENST0000032189213302338_236119353047.0Compositional biasNote=Thr-rich
TgeneBPTFchr17:76400170chr17:65916131ENST0000032189213302795_281719353047.0Compositional biasNote=Pro-rich
TgeneBPTFchr17:76400170chr17:65916131ENST0000032189213302848_285319353047.0Compositional biasNote=Poly-Lys
TgeneBPTFchr17:76400170chr17:65916131ENST0000033522113302338_236119352904.0Compositional biasNote=Thr-rich
TgeneBPTFchr17:76400170chr17:65916131ENST0000033522113302795_281719352904.0Compositional biasNote=Pro-rich
TgeneBPTFchr17:76400170chr17:65916131ENST0000033522113302848_285319352904.0Compositional biasNote=Poly-Lys
TgeneBPTFchr17:76400170chr17:65916130ENST0000030637811282944_301418092921.0DomainBromo
TgeneBPTFchr17:76400170chr17:65916130ENST0000032189213302944_301419353047.0DomainBromo
TgeneBPTFchr17:76400170chr17:65916130ENST0000033522113302944_301419352904.0DomainBromo
TgeneBPTFchr17:76400170chr17:65916131ENST0000030637811282944_301418092921.0DomainBromo
TgeneBPTFchr17:76400170chr17:65916131ENST0000032189213302944_301419353047.0DomainBromo
TgeneBPTFchr17:76400170chr17:65916131ENST0000033522113302944_301419352904.0DomainBromo
TgeneBPTFchr17:76400170chr17:65916130ENST0000030637811282867_291818092921.0Zinc fingerPHD-type 2
TgeneBPTFchr17:76400170chr17:65916130ENST0000032189213302867_291819353047.0Zinc fingerPHD-type 2
TgeneBPTFchr17:76400170chr17:65916130ENST0000033522113302867_291819352904.0Zinc fingerPHD-type 2
TgeneBPTFchr17:76400170chr17:65916131ENST0000030637811282867_291818092921.0Zinc fingerPHD-type 2
TgeneBPTFchr17:76400170chr17:65916131ENST0000032189213302867_291819353047.0Zinc fingerPHD-type 2
TgeneBPTFchr17:76400170chr17:65916131ENST0000033522113302867_291819352904.0Zinc fingerPHD-type 2

- In-frame and not-retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
HgenePGS1chr17:76400170chr17:65916130ENST00000262764+710460_493467665.3333333333334DomainPLD phosphodiesterase 2
HgenePGS1chr17:76400170chr17:65916131ENST00000262764+710460_493467665.3333333333334DomainPLD phosphodiesterase 2
TgeneBPTFchr17:76400170chr17:65916130ENST000003063781128574_60418092921.0Coiled coilOntology_term=ECO:0000255
TgeneBPTFchr17:76400170chr17:65916130ENST000003063781128978_100718092921.0Coiled coilOntology_term=ECO:0000255
TgeneBPTFchr17:76400170chr17:65916130ENST000003218921330574_60419353047.0Coiled coilOntology_term=ECO:0000255
TgeneBPTFchr17:76400170chr17:65916130ENST000003218921330978_100719353047.0Coiled coilOntology_term=ECO:0000255
TgeneBPTFchr17:76400170chr17:65916130ENST000003352211330574_60419352904.0Coiled coilOntology_term=ECO:0000255
TgeneBPTFchr17:76400170chr17:65916130ENST000003352211330978_100719352904.0Coiled coilOntology_term=ECO:0000255
TgeneBPTFchr17:76400170chr17:65916131ENST000003063781128574_60418092921.0Coiled coilOntology_term=ECO:0000255
TgeneBPTFchr17:76400170chr17:65916131ENST000003063781128978_100718092921.0Coiled coilOntology_term=ECO:0000255
TgeneBPTFchr17:76400170chr17:65916131ENST000003218921330574_60419353047.0Coiled coilOntology_term=ECO:0000255
TgeneBPTFchr17:76400170chr17:65916131ENST000003218921330978_100719353047.0Coiled coilOntology_term=ECO:0000255
TgeneBPTFchr17:76400170chr17:65916131ENST000003352211330574_60419352904.0Coiled coilOntology_term=ECO:0000255
TgeneBPTFchr17:76400170chr17:65916131ENST000003352211330978_100719352904.0Coiled coilOntology_term=ECO:0000255
TgeneBPTFchr17:76400170chr17:65916130ENST000003063781128143_18018092921.0Compositional biasNote=Glu-rich
TgeneBPTFchr17:76400170chr17:65916130ENST000003063781128149_18518092921.0Compositional biasNote=Asp-rich
TgeneBPTFchr17:76400170chr17:65916130ENST0000030637811281709_180318092921.0Compositional biasNote=Thr-rich
TgeneBPTFchr17:76400170chr17:65916130ENST000003218921330143_18019353047.0Compositional biasNote=Glu-rich
TgeneBPTFchr17:76400170chr17:65916130ENST000003218921330149_18519353047.0Compositional biasNote=Asp-rich
TgeneBPTFchr17:76400170chr17:65916130ENST0000032189213301709_180319353047.0Compositional biasNote=Thr-rich
TgeneBPTFchr17:76400170chr17:65916130ENST000003352211330143_18019352904.0Compositional biasNote=Glu-rich
TgeneBPTFchr17:76400170chr17:65916130ENST000003352211330149_18519352904.0Compositional biasNote=Asp-rich
TgeneBPTFchr17:76400170chr17:65916130ENST0000033522113301709_180319352904.0Compositional biasNote=Thr-rich
TgeneBPTFchr17:76400170chr17:65916131ENST000003063781128143_18018092921.0Compositional biasNote=Glu-rich
TgeneBPTFchr17:76400170chr17:65916131ENST000003063781128149_18518092921.0Compositional biasNote=Asp-rich
TgeneBPTFchr17:76400170chr17:65916131ENST0000030637811281709_180318092921.0Compositional biasNote=Thr-rich
TgeneBPTFchr17:76400170chr17:65916131ENST000003218921330143_18019353047.0Compositional biasNote=Glu-rich
TgeneBPTFchr17:76400170chr17:65916131ENST000003218921330149_18519353047.0Compositional biasNote=Asp-rich
TgeneBPTFchr17:76400170chr17:65916131ENST0000032189213301709_180319353047.0Compositional biasNote=Thr-rich
TgeneBPTFchr17:76400170chr17:65916131ENST000003352211330143_18019352904.0Compositional biasNote=Glu-rich
TgeneBPTFchr17:76400170chr17:65916131ENST000003352211330149_18519352904.0Compositional biasNote=Asp-rich
TgeneBPTFchr17:76400170chr17:65916131ENST0000033522113301709_180319352904.0Compositional biasNote=Thr-rich
TgeneBPTFchr17:76400170chr17:65916130ENST000003063781128240_30018092921.0DomainDDT
TgeneBPTFchr17:76400170chr17:65916130ENST000003218921330240_30019353047.0DomainDDT
TgeneBPTFchr17:76400170chr17:65916130ENST000003352211330240_30019352904.0DomainDDT
TgeneBPTFchr17:76400170chr17:65916131ENST000003063781128240_30018092921.0DomainDDT
TgeneBPTFchr17:76400170chr17:65916131ENST000003218921330240_30019353047.0DomainDDT
TgeneBPTFchr17:76400170chr17:65916131ENST000003352211330240_30019352904.0DomainDDT
TgeneBPTFchr17:76400170chr17:65916130ENST000003063781128390_43718092921.0Zinc fingerPHD-type 1
TgeneBPTFchr17:76400170chr17:65916130ENST000003218921330390_43719353047.0Zinc fingerPHD-type 1
TgeneBPTFchr17:76400170chr17:65916130ENST000003352211330390_43719352904.0Zinc fingerPHD-type 1
TgeneBPTFchr17:76400170chr17:65916131ENST000003063781128390_43718092921.0Zinc fingerPHD-type 1
TgeneBPTFchr17:76400170chr17:65916131ENST000003218921330390_43719353047.0Zinc fingerPHD-type 1
TgeneBPTFchr17:76400170chr17:65916131ENST000003352211330390_43719352904.0Zinc fingerPHD-type 1


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Fusion Gene Sequence for PGS1-BPTF


check button For in-frame fusion transcripts, we provide the fusion transcript sequences and fusion amino acid sequences. To have fusion amino acid sequence, we ran ORFfinder and chose the longest ORF among the all predicted ones.
>64664_64664_1_PGS1-BPTF_PGS1_chr17_76400170_ENST00000262764_BPTF_chr17_65916130_ENST00000306378_length(transcript)=5628nt_BP=1428nt
AGCGGAAGCGGAAGCGGCGAGTCTCCATGGCGGTGGCGGCGGCAGCTGCGGCGGGACCCGTGTTCTGGAGGCGACTGCTGGGCCTCCTGC
CTGGCCGCCCAGGGCTGGCCGCGCTCCTGGGACGCCTGTCCGACCGCCTCGGCAGGAACCGGGACCGCCAGCGCAGGAGGTCACCATGGC
TGTTATTGGCTCCCTTGCTGTCCCCAGCTGTTCCCCAGGTCACCTCCCCACCTTGCTGCCTGTGTCCAGAAGGCGTGCACCGGTTCCAGT
GGATCAGAAACCTGGTTCCAGAATTTGGAGTCTCCAGTTCTCACGTTAGGGTGCTTTCTTCCCCGGCAGAGTTTTTCGAGCTCATGAAGG
GGCAGATAAGAGTAGCCAAGAGGCGGGTCGTGATGGCATCCCTCTACCTGGGGACAGGTCCTTTGGAACAGGAGCTGGTGGACTGCCTGG
AAAGTACTCTAGAAAAGTCACTCCAAGCAAAGTTTCCTTCAAATCTCAAGGTCTCCATTCTCTTAGACTTCACGCGGGGCTCACGAGGCC
GGAAGAACTCCCGCACAATGCTGCTCCCACTCCTGCGGAGGTTCCCAGAGCAGGTCCGAGTCTCCCTCTTTCACACGCCGCACCTCCGTG
GGCTGCTTCGGCTCCTCATCCCTGAGCGCTTCAACGAGACCATCGGCCTCCAGCACATTAAGGTGTACCTCTTCGACAACAGCGTCATCT
TGAGCGGTGCAAACCTGAGTGACTCCTACTTCACCAACCGCCAGGACCGCTACGTGTTCCTGCAGGACTGTGCGGAGATTGCCGACTTCT
TCACGGAGCTGGTGGACGCGGTGGGGGATGTGTCCCTGCAGCTGCAGGGGGACGACACGGTGCAGGTGGTGGATGGGATGGTGCATCCTT
ACAAAGGGGACCGGGCCGAGTACTGCAAGGCAGCCAATAAGAGGGTCATGGATGTGATCAACTCAGCCAGGACCCGCCAGCAGATGCTGC
ATGCCCAGACCTTCCACAGCAACTCTCTTTTGACCCAGGAAGATGCAGCAGCTGCTGGGGATCGCAGACCAGCCCCTGACACCTGGATTT
ATCCGCTGATTCAGATGAAGCCCTTCGAGATTCAAATCGATGAGATTGTCACTGAGACCCTGTTGACTGAGGCGGAGCGCGGGGCAAAGG
TCTACCTCACCACTGGCTATTTCAACCTGACCCAGGCCTACATGGACCTGGTCTTGGGCACTCGGGCTGAGTACCAGATCCTGCTGGCCT
CACCAGAGGTGAATGGCTTCTTTGGGGCCAAGGGGGTGGCCGGCGCCATCCCAGCGGCCTATGTGCACATCGAGCGACAGTTCTTCAGTG
AGGTGTGCAGCCTGGGACAGCAGGAGCGGGTCCAGCTTCAGGAGTACTGGCGGAGGGGCTGGACGTTCCACGCCAAAGAAACATCCGAAA
CTGAAATCACAACAACAGAAATAATTAAGAGGAGAGATGTTGGTCCTTATGGCATTCGATCTGAATATTGTATCAGGAAAATCATTTGTC
CCATTGGAGTTCCAGAAACACCAAAAGAAACGCCTACACCTCAGAGGAAAGGCCTTCGATCAAGTGCACTGCGGCCAAAGAGACCAGAAA
CGCCCAAGCAAACTGGCCCTGTTATTATTGAAACCTGGGTAGCAGAAGAAGAACTGGAATTGTGGGAGATCAGGGCATTTGCTGAGAGAG
TGGAGAAAGAAAAGGCACAAGCAGTTGAGCAACAGGCTAAGAAACGACTGGAGCAGCAGAAGCCGACAGTGATTGCAACTTCCACTACTT
CCCCAACAAGCAGTACAACCAGCACCATCTCTCCAGCACAGAAGGTTATGGTGGCCCCCATAAGTGGCTCAGTTACAACTGGAACCAAAA
TGGTACTAACTACTAAAGTTGGATCTCCAGCTACAGTAACATTCCAACAAAACAAGAACTTTCATCAAACCTTTGCTACATGGGTTAAGC
AAGGCCAGTCAAATTCAGGCGTTGTTCAAGTACAGCAGAAAGTCCTGGGTATCATTCCATCAAGTACAGGTACCAGTCAGCAAACCTTTA
CTTCATTCCAGCCCAGGACAGCAACAGTCACAATTAGGCCCAATACCTCAGGCTCTGGAGGAACCACAAGCAATTCACAAGTAATCACAG
GGCCTCAGATTCGCCCTGGTATGACCGTGATTAGAACACCACTCCAACAGTCAACACTAGGAAAGGCAATTATTCGAACACCTGTGATGG
TACAGCCAGGTGCTCCTCAGCAAGTGATGACTCAAATCATCAGGGGGCAGCCTGTCTCCACTGCAGTCTCCGCCCCTAACACGGTTTCCT
CAACACCTGGGCAGAAAAGCTTAACTTCAGCAACGTCCACTTCAAATATACAGTCTTCAGCCTCACAACCCCCTCGCCCCCAACAAGGAC
AAGTGAAGCTCACCATGGCTCAACTTACTCAGTTAACACAGGGCCACGGTGGCAATCAAGGTTTGACAGTAGTAATTCAAGGACAAGGTC
AAACTACTGGACAGTTGCAGTTGATACCTCAAGGGGTGACTGTACTCCCAGGCCCAGGCCAGCAGCTAATGCAAGCTGCAATGCCAAATG
GTACTGTTCAGCGATTCCTCTTTACCCCATTGGCAACAACAGCCACCACAGCCAGCACCACCACCACCACTGTTTCCACGACAGCAGCAG
GTACAGGTGAACAAAGGCAGAGTAAACTGTCACCCCAGATGCAGGTACATCAAGACAAAACCCTGCCACCAGCTCAGTCATCAAGTGTGG
GTCCAGCAGAAGCCCAGCCACAGACTGCTCAGCCTTCAGCTCAGCCCCAGCCCCAAACCCAGCCCCAGTCCCCAGCTCAGCCTGAAGTTC
AGACTCAGCCTGAAGTTCAGACCCAAACAACTGTTTCATCCCATGTCCCTTCTGAAGCACAACCCACCCACGCACAGTCATCCAAGCCCC
AAGTTGCAGCACAGTCTCAGCCTCAAAGTAATGTCCAAGGACAGTCTCCTGTTCGTGTCCAAAGTCCATCACAGACTCGAATACGTCCAT
CAACTCCATCCCAACTGTCTCCTGGACAACAATCCCAGGTTCAGACTACAACCTCACAACCGATTCCAATTCAACCACATACATCTCTTC
AGATACCTTCCCAAGGCCAGCCACAGTCACAACCCCAGGTACAGTCTTCAACTCAAACTCTTTCATCAGGACAAACTTTAAATCAAGTTA
CTGTTTCATCCCCATCCCGTCCTCAGCTACAAATACAGCAGCCACAGCCCCAAGTCATTGCTGTGCCTCAGCTGCAACAACAAGTCCAGG
TTCTCTCTCAGATCCAGTCACAGGTTGTGGCTCAGATACAGGCTCAGCAAAGTGGTGTGCCCCAGCAAATCAAACTCCAGTTACCTATCC
AAATTCAGCAAAGCAGTGCTGTGCAGACTCACCAGATTCAGAATGTGGTTACAGTGCAGGCAGCCAGTGTGCAAGAGCAGTTGCAAAGGG
TTCAGCAACTCAGGGATCAGCAGCAAAAGAAGAAACAGCAACAGATAGAAATTAAGCGTGAACACACCCTCCAAGCTTCTAATCAAAGTG
AAATCATTCAGAAACAGGTGGTGATGAAGCATAATGCTGTAATAGAACATTTAAAACAGAAAAAGAGCATGACTCCAGCTGAAAGAGAAG
AGAATCAAAGAATGATTGTCTGTAACCAGGTGATGAAGTATATTTTGGATAAGATAGATAAAGAAGAAAAACAGGCAGCAAAAAAACGGA
AGCGTGAAGAGAGTGTGGAGCAGAAACGTAGCAAGCAGAATGCCACTAAGCTGTCAGCTCTGCTCTTCAAGCACAAAGAGCAGCTCAGAG
CCGAGATCCTGAAGAAGAGAGCACTCCTGGACAAGGATCTGCAAATTGAAGTGCAGGAAGAGCTGAAGAGAGACCTGAAAATTAAGAAAG
AAAAAGACCTGATGCAGTTGGCTCAGGCCACAGCAGTAGCTGCACCCTGCCCCCCAGTGACACCAGCTCCTCCAGCCCCTCCAGCCCCTC
CACCTTCACCTCCCCCTCCACCTGCTGTGCAACACACAGGCCTTCTGTCCACGCCCACCTTACCTGCTGCTTCCCAGAAGAGGAAGCGGG
AAGAGGAAAAAGACTCCAGCTCAAAGTCCAAGAAAAAGAAAATGATCTCTACTACCTCAAAGGAAACTAAGAAGGACACAAAGCTTTACT
GTATCTGTAAAACGCCTTATGATGAATCTAAATTTTATATTGGCTGTGATCGGTGTCAGAATTGGTACCATGGGCGCTGCGTTGGCATCT
TGCAAAGTGAGGCAGAGCTCATTGATGAGTATGTCTGTCCACAGTGCCAGTCAACAGAGGATGCCATGACAGTGCTCACGCCACTAACAG
AGAAGGATTATGAGGGGTTGAAGAGGGTGCTCCGTTCCTTACAGGCCCATAAGATGGCCTGGCCTTTCCTTGAACCAGTAGACCCTAATG
ATGCACCAGATTATTATGGTGTTATTAAGGAACCTATGGACCTTGCCACCATGGAAGAAAGAGTACAAAGACGATATTATGAAAAGCTGA
CGGAATTTGTGGCAGATATGACCAAAATTTTTGATAACTGTCGTTACTACAATCCAAGTGACTCCCCATTTTACCAGTGTGCAGAAGTTC
TCGAATCATTCTTTGTACAGAAATTGAAAGGCTTCAAAGCTAGCAGGTCTCATAACAACAAACTGCAGTCTACAGCTTCTTAAAGTTCAG
CGTGTTAACCTAACATAAAACACAGCAAGAATCTGGTTGTCTGAACTATTTTAAATTAAGGAGCCAGATGTTTTTAGTCAGGCTATCCTG
ACAAGACTTGACCTAAACTTCGTTTTTATTGGTCATAACAGTCCAATTATATTCTTGGCCAATTTTGTCCAACGGACAAGAAAAAAGCAA
AGTCAACGACACCATTATCTTGTCAAGATCAGATGGTTTTACTATTGTGGCAGAAGCGAGAAAACTTTGTTTATTGAAAAAAAAAGAAAA
AGAAAGCAAGAAAAAAAGATACTATGGGGTCAAGTGTAACTCCATGGAAATGCCACGTCTGCTCTTCAGTGAAGAAGCTGGTTTAGAGTC
TCACAGAAAACTTTTGACTGTATTTATTTATTGTTGCAAAAAAGACGCTTTTTTATTGCTGCCCTCATTTGTCAGCTAATTATTTTTTCT
TATAAAATCCAGCCCCGGTTACATATAATCATCTGTATCTTATCATGATTCCTGTAGGTAAAAGTACAAGACGACCTCTAGATGTCTTTT
CTTTCTATGAAAGGAGCTGCTATGTACACATGTGCACACACACACAACTGGGAATCAACAATGAGTTTATTGTTCATGGTAGATTAAAAT
TAAGCTTGCATAAAGGTTGGGCTAAGTGGTCCTGGACTACAGACTCTGTTGCCTTGAATATAACAGTACAATTTGTCAATTACTCTGCAC
CAGGCTAAAATGAGTAAAATCTATTTGAAGGTATCTTGTTTGTAAACATTTGTCAGATTCTAATTTTTTTCTTTTGTATTAAAATTCAAC

>64664_64664_1_PGS1-BPTF_PGS1_chr17_76400170_ENST00000262764_BPTF_chr17_65916130_ENST00000306378_length(amino acids)=1578AA_BP=467
MAVAAAAAAGPVFWRRLLGLLPGRPGLAALLGRLSDRLGRNRDRQRRRSPWLLLAPLLSPAVPQVTSPPCCLCPEGVHRFQWIRNLVPEF
GVSSSHVRVLSSPAEFFELMKGQIRVAKRRVVMASLYLGTGPLEQELVDCLESTLEKSLQAKFPSNLKVSILLDFTRGSRGRKNSRTMLL
PLLRRFPEQVRVSLFHTPHLRGLLRLLIPERFNETIGLQHIKVYLFDNSVILSGANLSDSYFTNRQDRYVFLQDCAEIADFFTELVDAVG
DVSLQLQGDDTVQVVDGMVHPYKGDRAEYCKAANKRVMDVINSARTRQQMLHAQTFHSNSLLTQEDAAAAGDRRPAPDTWIYPLIQMKPF
EIQIDEIVTETLLTEAERGAKVYLTTGYFNLTQAYMDLVLGTRAEYQILLASPEVNGFFGAKGVAGAIPAAYVHIERQFFSEVCSLGQQE
RVQLQEYWRRGWTFHAKETSETEITTTEIIKRRDVGPYGIRSEYCIRKIICPIGVPETPKETPTPQRKGLRSSALRPKRPETPKQTGPVI
IETWVAEEELELWEIRAFAERVEKEKAQAVEQQAKKRLEQQKPTVIATSTTSPTSSTTSTISPAQKVMVAPISGSVTTGTKMVLTTKVGS
PATVTFQQNKNFHQTFATWVKQGQSNSGVVQVQQKVLGIIPSSTGTSQQTFTSFQPRTATVTIRPNTSGSGGTTSNSQVITGPQIRPGMT
VIRTPLQQSTLGKAIIRTPVMVQPGAPQQVMTQIIRGQPVSTAVSAPNTVSSTPGQKSLTSATSTSNIQSSASQPPRPQQGQVKLTMAQL
TQLTQGHGGNQGLTVVIQGQGQTTGQLQLIPQGVTVLPGPGQQLMQAAMPNGTVQRFLFTPLATTATTASTTTTTVSTTAAGTGEQRQSK
LSPQMQVHQDKTLPPAQSSSVGPAEAQPQTAQPSAQPQPQTQPQSPAQPEVQTQPEVQTQTTVSSHVPSEAQPTHAQSSKPQVAAQSQPQ
SNVQGQSPVRVQSPSQTRIRPSTPSQLSPGQQSQVQTTTSQPIPIQPHTSLQIPSQGQPQSQPQVQSSTQTLSSGQTLNQVTVSSPSRPQ
LQIQQPQPQVIAVPQLQQQVQVLSQIQSQVVAQIQAQQSGVPQQIKLQLPIQIQQSSAVQTHQIQNVVTVQAASVQEQLQRVQQLRDQQQ
KKKQQQIEIKREHTLQASNQSEIIQKQVVMKHNAVIEHLKQKKSMTPAEREENQRMIVCNQVMKYILDKIDKEEKQAAKKRKREESVEQK
RSKQNATKLSALLFKHKEQLRAEILKKRALLDKDLQIEVQEELKRDLKIKKEKDLMQLAQATAVAAPCPPVTPAPPAPPAPPPSPPPPPA
VQHTGLLSTPTLPAASQKRKREEEKDSSSKSKKKKMISTTSKETKKDTKLYCICKTPYDESKFYIGCDRCQNWYHGRCVGILQSEAELID
EYVCPQCQSTEDAMTVLTPLTEKDYEGLKRVLRSLQAHKMAWPFLEPVDPNDAPDYYGVIKEPMDLATMEERVQRRYYEKLTEFVADMTK

--------------------------------------------------------------
>64664_64664_2_PGS1-BPTF_PGS1_chr17_76400170_ENST00000262764_BPTF_chr17_65916130_ENST00000321892_length(transcript)=6853nt_BP=1428nt
AGCGGAAGCGGAAGCGGCGAGTCTCCATGGCGGTGGCGGCGGCAGCTGCGGCGGGACCCGTGTTCTGGAGGCGACTGCTGGGCCTCCTGC
CTGGCCGCCCAGGGCTGGCCGCGCTCCTGGGACGCCTGTCCGACCGCCTCGGCAGGAACCGGGACCGCCAGCGCAGGAGGTCACCATGGC
TGTTATTGGCTCCCTTGCTGTCCCCAGCTGTTCCCCAGGTCACCTCCCCACCTTGCTGCCTGTGTCCAGAAGGCGTGCACCGGTTCCAGT
GGATCAGAAACCTGGTTCCAGAATTTGGAGTCTCCAGTTCTCACGTTAGGGTGCTTTCTTCCCCGGCAGAGTTTTTCGAGCTCATGAAGG
GGCAGATAAGAGTAGCCAAGAGGCGGGTCGTGATGGCATCCCTCTACCTGGGGACAGGTCCTTTGGAACAGGAGCTGGTGGACTGCCTGG
AAAGTACTCTAGAAAAGTCACTCCAAGCAAAGTTTCCTTCAAATCTCAAGGTCTCCATTCTCTTAGACTTCACGCGGGGCTCACGAGGCC
GGAAGAACTCCCGCACAATGCTGCTCCCACTCCTGCGGAGGTTCCCAGAGCAGGTCCGAGTCTCCCTCTTTCACACGCCGCACCTCCGTG
GGCTGCTTCGGCTCCTCATCCCTGAGCGCTTCAACGAGACCATCGGCCTCCAGCACATTAAGGTGTACCTCTTCGACAACAGCGTCATCT
TGAGCGGTGCAAACCTGAGTGACTCCTACTTCACCAACCGCCAGGACCGCTACGTGTTCCTGCAGGACTGTGCGGAGATTGCCGACTTCT
TCACGGAGCTGGTGGACGCGGTGGGGGATGTGTCCCTGCAGCTGCAGGGGGACGACACGGTGCAGGTGGTGGATGGGATGGTGCATCCTT
ACAAAGGGGACCGGGCCGAGTACTGCAAGGCAGCCAATAAGAGGGTCATGGATGTGATCAACTCAGCCAGGACCCGCCAGCAGATGCTGC
ATGCCCAGACCTTCCACAGCAACTCTCTTTTGACCCAGGAAGATGCAGCAGCTGCTGGGGATCGCAGACCAGCCCCTGACACCTGGATTT
ATCCGCTGATTCAGATGAAGCCCTTCGAGATTCAAATCGATGAGATTGTCACTGAGACCCTGTTGACTGAGGCGGAGCGCGGGGCAAAGG
TCTACCTCACCACTGGCTATTTCAACCTGACCCAGGCCTACATGGACCTGGTCTTGGGCACTCGGGCTGAGTACCAGATCCTGCTGGCCT
CACCAGAGGTGAATGGCTTCTTTGGGGCCAAGGGGGTGGCCGGCGCCATCCCAGCGGCCTATGTGCACATCGAGCGACAGTTCTTCAGTG
AGGTGTGCAGCCTGGGACAGCAGGAGCGGGTCCAGCTTCAGGAGTACTGGCGGAGGGGCTGGACGTTCCACGCCAAAGAAACATCCGAAA
CTGAAATCACAACAACAGAAATAATTAAGAGGAGAGATGTTGGTCCTTATGGCATTCGATCTGAATATTGTATCAGGAAAATCATTTGTC
CCATTGGAGTTCCAGAAACACCAAAAGAAACGCCTACACCTCAGAGGAAAGGCCTTCGATCAAGTGCACTGCGGCCAAAGAGACCAGAAA
CGCCCAAGCAAACTGGCCCTGTTATTATTGAAACCTGGGTAGCAGAAGAAGAACTGGAATTGTGGGAGATCAGGGCATTTGCTGAGAGAG
TGGAGAAAGAAAAGGCACAAGCAGTTGAGCAACAGGCTAAGAAACGACTGGAGCAGCAGAAGCCGACAGTGATTGCAACTTCCACTACTT
CCCCAACAAGCAGTACAACCAGCACCATCTCTCCAGCACAGAAGGTTATGGTGGCCCCCATAAGTGGCTCAGTTACAACTGGAACCAAAA
TGGTACTAACTACTAAAGTTGGATCTCCAGCTACAGTAACATTCCAACAAAACAAGAACTTTCATCAAACCTTTGCTACATGGGTTAAGC
AAGGCCAGTCAAATTCAGGCGTTGTTCAAGTACAGCAGAAAGTCCTGGGTATCATTCCATCAAGTACAGGTACCAGTCAGCAAACCTTTA
CTTCATTCCAGCCCAGGACAGCAACAGTCACAATTAGGCCCAATACCTCAGGCTCTGGAGGAACCACAAGCAATTCACAAGTAATCACAG
GGCCTCAGATTCGCCCTGGTATGACCGTGATTAGAACACCACTCCAACAGTCAACACTAGGAAAGGCAATTATTCGAACACCTGTGATGG
TACAGCCAGGTGCTCCTCAGCAAGTGATGACTCAAATCATCAGGGGGCAGCCTGTCTCCACTGCAGTCTCCGCCCCTAACACGGTTTCCT
CAACACCTGGGCAGAAAAGCTTAACTTCAGCAACGTCCACTTCAAATATACAGTCTTCAGCCTCACAACCCCCTCGCCCCCAACAAGGAC
AAGTGAAGCTCACCATGGCTCAACTTACTCAGTTAACACAGGGCCACGGTGGCAATCAAGGTTTGACAGTAGTAATTCAAGGACAAGGTC
AAACTACTGGACAGTTGCAGTTGATACCTCAAGGGGTGACTGTACTCCCAGGCCCAGGCCAGCAGCTAATGCAAGCTGCAATGCCAAATG
GTACTGTTCAGCGATTCCTCTTTACCCCATTGGCAACAACAGCCACCACAGCCAGCACCACCACCACCACTGTTTCCACGACAGCAGCAG
GTACAGGTGAACAAAGGCAGAGTAAACTGTCACCCCAGATGCAGGTACATCAAGACAAAACCCTGCCACCAGCTCAGTCATCAAGTGTGG
GTCCAGCAGAAGCCCAGCCACAGACTGCTCAGCCTTCAGCTCAGCCCCAGCCCCAAACCCAGCCCCAGTCCCCAGCTCAGCCTGAAGTTC
AGACTCAGCCTGAAGTTCAGACCCAAACAACTGTTTCATCCCATGTCCCTTCTGAAGCACAACCCACCCACGCACAGTCATCCAAGCCCC
AAGTTGCAGCACAGTCTCAGCCTCAAAGTAATGTCCAAGGACAGTCTCCTGTTCGTGTCCAAAGTCCATCACAGACTCGAATACGTCCAT
CAACTCCATCCCAACTGTCTCCTGGACAACAATCCCAGGTTCAGACTACAACCTCACAACCGATTCCAATTCAACCACATACATCTCTTC
AGATACCTTCCCAAGGCCAGCCACAGTCACAACCCCAGGTACAGTCTTCAACTCAAACTCTTTCATCAGGACAAACTTTAAATCAAGTTA
CTGTTTCATCCCCATCCCGTCCTCAGCTACAAATACAGCAGCCACAGCCCCAAGTCATTGCTGTGCCTCAGCTGCAACAACAAGTCCAGG
TTCTCTCTCAGATCCAGTCACAGGTTGTGGCTCAGATACAGGCTCAGCAAAGTGGTGTGCCCCAGCAAATCAAACTCCAGTTACCTATCC
AAATTCAGCAAAGCAGTGCTGTGCAGACTCACCAGATTCAGAATGTGGTTACAGTGCAGGCAGCCAGTGTGCAAGAGCAGTTGCAAAGGG
TTCAGCAACTCAGGGATCAGCAGCAAAAGAAGAAACAGCAACAGATAGAAATTAAGCGTGAACACACCCTCCAAGCTTCTAATCAAAGTG
AAATCATTCAGAAACAGGTGGTGATGAAGCATAATGCTGTAATAGAACATTTAAAACAGAAAAAGAGCATGACTCCAGCTGAAAGAGAAG
AGAATCAAAGAATGATTGTCTGTAACCAGGTGATGAAGTATATTTTGGATAAGATAGATAAAGAAGAAAAACAGGCAGCAAAAAAACGGA
AGCGTGAAGAGAGTGTGGAGCAGAAACGTAGCAAGCAGAATGCCACTAAGCTGTCAGCTCTGCTCTTCAAGCACAAAGAGCAGCTCAGAG
CCGAGATCCTGAAGAAGAGAGCACTCCTGGACAAGGATCTGCAAATTGAAGTGCAGGAAGAGCTGAAGAGAGACCTGAAAATTAAGAAAG
AAAAAGACCTGATGCAGTTGGCTCAGGCCACAGCAGTAGCTGCACCCTGCCCCCCAGTGACACCAGCTCCTCCAGCCCCTCCAGCCCCTC
CACCTTCACCTCCCCCTCCACCTGCTGTGCAACACACAGGCCTTCTGTCCACGCCCACCTTACCTGCTGCTTCCCAGAAGAGGAAGCGGG
AAGAGGAAAAAGACTCCAGCTCAAAGTCCAAGAAAAAGAAAATGATCTCTACTACCTCAAAGGAAACTAAGAAGGACACAAAGCTTTACT
GTATCTGTAAAACGCCTTATGATGAATCTAAATTTTATATTGGCTGTGATCGGTGTCAGAATTGGTACCATGGGCGCTGCGTTGGCATCT
TGCAAAGTGAGGCAGAGCTCATTGATGAGTATGTCTGTCCACAGTGCCAGTCAACAGAGGATGCCATGACAGTGCTCACGCCACTAACAG
AGAAGGATTATGAGGGGTTGAAGAGGGTGCTCCGTTCCTTACAGGCCCATAAGATGGCCTGGCCTTTCCTTGAACCAGTAGACCCTAATG
ATGCACCAGATTATTATGGTGTTATTAAGGAACCTATGGACCTTGCCACCATGGAAGAAAGAGTACAAAGACGATATTATGAAAAGCTGA
CGGAATTTGTGGCAGATATGACCAAAATTTTTGATAACTGTCGTTACTACAATCCAAGTGACTCCCCATTTTACCAGTGTGCAGAAGTTC
TCGAATCATTCTTTGTACAGAAATTGAAAGGCTTCAAAGCTAGCAGGTCTCATAACAACAAACTGCAGTCTACAGCTTCTTAAAGTTCAG
CGTGTTAACCTAACATAAAACACAGCAAGAATCTGGTTGTCTGAACTATTTTAAATTAAGGAGCCAGATGTTTTTAGTCAGGCTATCCTG
ACAAGACTTGACCTAAACTTCGTTTTTATTGGTCATAACAGTCCAATTATATTCTTGGCCAATTTTGTCCAACGGACAAGAAAAAAGCAA
AGTCAACGACACCATTATCTTGTCAAGATCAGATGGTTTTACTATTGTGGCAGAAGCGAGAAAACTTTGTTTATTGAAAAAAAAAGAAAA
AGAAAGCAAGAAAAAAAGATACTATGGGGTCAAGTGTAACTCCATGGAAATGCCACGTCTGCTCTTCAGTGAAGAAGCTGGTTTAGAGTC
TCACAGAAAACTTTTGACTGTATTTATTTATTGTTGCAAAAAAGACGCTTTTTTATTGCTGCCCTCATTTGTCAGCTAATTATTTTTTCT
TATAAAATCCAGCCCCGGTTACATATAATCATCTGTATCTTATCATGATTCCTGTAGGTAAAAGTACAAGACGACCTCTAGATGTCTTTT
CTTTCTATGAAAGGAGCTGCTATGTACACATGTGCACACACACACAACTGGGAATCAACAATGAGTTTATTGTTCATGGTAGATTAAAAT
TAAGCTTGCATAAAGGTTGGGCTAAGTGGTCCTGGACTACAGACTCTGTTGCCTTGAATATAACAGTACAATTTGTCAATTACTCTGCAC
CAGGCTAAAATGAGTAAAATCTATTTGAAGGTATCTTGTTTGTAAACATTTGTCAGATTCTAATTTTTTTCTTTTGTATTAAAATTCAAC
TATGGATGTATATGAAACAAAATAAATGGAGATAATTTTTCTCCCACAGACAGAGGTGTCTTTGAATGTGCGCTAATGATTATCTGTAAG
CCTTTGTGGGGAGGGAGGCCTGCAAGGTCATGAAAGGCAGAAGAGTCTAATTGTGCCTGGATTTCTCCAGGACAGCAGTGGCCCCTCGTT
TTATCATTCCCAGTCCATTGTCATCACGTCAGAGAAAAATCTTCAGGGGTGCTAATCCTGTTGCATCAGTTGATCATACTAACGAGAACG
GTAATGCGACAAGATACACATTGCCTTCATCTGTACATTCTGTGATACCAGGCAAATTACCAATTACACACAGCTACTTATATTTTATGA
AGGGCATTTTTTAGATGACCTCATCCTCTGTGTTATTTGTTGATTGGGTTTGTTTTCTGTTTGTTGGTTTGTTTGTTTCTTCCACGTAAG
GAAAAGTAGTGTAAACAGTAGCGAGAAAATGGAAACCACAGAGGAAGATGTATTTTGCATGTTTTTCCTTTCAGTGTTCTTACACGTTGT
ATCACTGCATTGTGGTAATAGCTTCTATAAAATCTGCCATAGTTGGATTATGCAGCTTTGCAAAAATTTTTACTAGATTTTGCACTAACT
CATATTAGCTTTGTCCTACCAACTTCTGGAATTTATCTAATTATTGTTTTTCAAAGTTTCTTTCCTTTTAATGTTTCCCTGCTATGCAAA
ACCTTTCCCAGACCTCAGTTTCTTAAAAGAAAGATGTTGCTACAGTTCCCGATTCTTTCTTATTACAGGCTCAGGTGTACAGGTTATTCT
GGGTTAATTTTATCTAATGAAGCCCATTCCTTTTTGTACATAAAGATGTCACTTAAACTTATGCTTACAAACTAAAGACTAATCGCTCAA
TATGAAAACATGAAAAAATTTTTGCTTAAAGTATTAAGATGGAAGTAGTTAAATATGGGTTATTTTGTCCTTTTACTTTTTTAAAAAATG
TTACATATTGTATGCACTGTGCTGATGCAAGAATTCTACATTTTAATGAGTTATAAAATTATTCTGCATCTCATCACGTCACAGTATTTC
TGTACTATTTATTCATATATATAAATATATATGGGCTTAATCATTTAAAATTTGTTGCAGCAAGAACTTTCCTACCTGTAGGCAATAGAT
TGCTATGTTTTTAACAAATTGTGGCAAATTCTAAACAGCAATTCTTTTGTACGTAATAGGACATTTCATCCTAGAAAAATAAAGTAATGT

>64664_64664_2_PGS1-BPTF_PGS1_chr17_76400170_ENST00000262764_BPTF_chr17_65916130_ENST00000321892_length(amino acids)=1578AA_BP=467
MAVAAAAAAGPVFWRRLLGLLPGRPGLAALLGRLSDRLGRNRDRQRRRSPWLLLAPLLSPAVPQVTSPPCCLCPEGVHRFQWIRNLVPEF
GVSSSHVRVLSSPAEFFELMKGQIRVAKRRVVMASLYLGTGPLEQELVDCLESTLEKSLQAKFPSNLKVSILLDFTRGSRGRKNSRTMLL
PLLRRFPEQVRVSLFHTPHLRGLLRLLIPERFNETIGLQHIKVYLFDNSVILSGANLSDSYFTNRQDRYVFLQDCAEIADFFTELVDAVG
DVSLQLQGDDTVQVVDGMVHPYKGDRAEYCKAANKRVMDVINSARTRQQMLHAQTFHSNSLLTQEDAAAAGDRRPAPDTWIYPLIQMKPF
EIQIDEIVTETLLTEAERGAKVYLTTGYFNLTQAYMDLVLGTRAEYQILLASPEVNGFFGAKGVAGAIPAAYVHIERQFFSEVCSLGQQE
RVQLQEYWRRGWTFHAKETSETEITTTEIIKRRDVGPYGIRSEYCIRKIICPIGVPETPKETPTPQRKGLRSSALRPKRPETPKQTGPVI
IETWVAEEELELWEIRAFAERVEKEKAQAVEQQAKKRLEQQKPTVIATSTTSPTSSTTSTISPAQKVMVAPISGSVTTGTKMVLTTKVGS
PATVTFQQNKNFHQTFATWVKQGQSNSGVVQVQQKVLGIIPSSTGTSQQTFTSFQPRTATVTIRPNTSGSGGTTSNSQVITGPQIRPGMT
VIRTPLQQSTLGKAIIRTPVMVQPGAPQQVMTQIIRGQPVSTAVSAPNTVSSTPGQKSLTSATSTSNIQSSASQPPRPQQGQVKLTMAQL
TQLTQGHGGNQGLTVVIQGQGQTTGQLQLIPQGVTVLPGPGQQLMQAAMPNGTVQRFLFTPLATTATTASTTTTTVSTTAAGTGEQRQSK
LSPQMQVHQDKTLPPAQSSSVGPAEAQPQTAQPSAQPQPQTQPQSPAQPEVQTQPEVQTQTTVSSHVPSEAQPTHAQSSKPQVAAQSQPQ
SNVQGQSPVRVQSPSQTRIRPSTPSQLSPGQQSQVQTTTSQPIPIQPHTSLQIPSQGQPQSQPQVQSSTQTLSSGQTLNQVTVSSPSRPQ
LQIQQPQPQVIAVPQLQQQVQVLSQIQSQVVAQIQAQQSGVPQQIKLQLPIQIQQSSAVQTHQIQNVVTVQAASVQEQLQRVQQLRDQQQ
KKKQQQIEIKREHTLQASNQSEIIQKQVVMKHNAVIEHLKQKKSMTPAEREENQRMIVCNQVMKYILDKIDKEEKQAAKKRKREESVEQK
RSKQNATKLSALLFKHKEQLRAEILKKRALLDKDLQIEVQEELKRDLKIKKEKDLMQLAQATAVAAPCPPVTPAPPAPPAPPPSPPPPPA
VQHTGLLSTPTLPAASQKRKREEEKDSSSKSKKKKMISTTSKETKKDTKLYCICKTPYDESKFYIGCDRCQNWYHGRCVGILQSEAELID
EYVCPQCQSTEDAMTVLTPLTEKDYEGLKRVLRSLQAHKMAWPFLEPVDPNDAPDYYGVIKEPMDLATMEERVQRRYYEKLTEFVADMTK

--------------------------------------------------------------
>64664_64664_3_PGS1-BPTF_PGS1_chr17_76400170_ENST00000262764_BPTF_chr17_65916130_ENST00000335221_length(transcript)=6424nt_BP=1428nt
AGCGGAAGCGGAAGCGGCGAGTCTCCATGGCGGTGGCGGCGGCAGCTGCGGCGGGACCCGTGTTCTGGAGGCGACTGCTGGGCCTCCTGC
CTGGCCGCCCAGGGCTGGCCGCGCTCCTGGGACGCCTGTCCGACCGCCTCGGCAGGAACCGGGACCGCCAGCGCAGGAGGTCACCATGGC
TGTTATTGGCTCCCTTGCTGTCCCCAGCTGTTCCCCAGGTCACCTCCCCACCTTGCTGCCTGTGTCCAGAAGGCGTGCACCGGTTCCAGT
GGATCAGAAACCTGGTTCCAGAATTTGGAGTCTCCAGTTCTCACGTTAGGGTGCTTTCTTCCCCGGCAGAGTTTTTCGAGCTCATGAAGG
GGCAGATAAGAGTAGCCAAGAGGCGGGTCGTGATGGCATCCCTCTACCTGGGGACAGGTCCTTTGGAACAGGAGCTGGTGGACTGCCTGG
AAAGTACTCTAGAAAAGTCACTCCAAGCAAAGTTTCCTTCAAATCTCAAGGTCTCCATTCTCTTAGACTTCACGCGGGGCTCACGAGGCC
GGAAGAACTCCCGCACAATGCTGCTCCCACTCCTGCGGAGGTTCCCAGAGCAGGTCCGAGTCTCCCTCTTTCACACGCCGCACCTCCGTG
GGCTGCTTCGGCTCCTCATCCCTGAGCGCTTCAACGAGACCATCGGCCTCCAGCACATTAAGGTGTACCTCTTCGACAACAGCGTCATCT
TGAGCGGTGCAAACCTGAGTGACTCCTACTTCACCAACCGCCAGGACCGCTACGTGTTCCTGCAGGACTGTGCGGAGATTGCCGACTTCT
TCACGGAGCTGGTGGACGCGGTGGGGGATGTGTCCCTGCAGCTGCAGGGGGACGACACGGTGCAGGTGGTGGATGGGATGGTGCATCCTT
ACAAAGGGGACCGGGCCGAGTACTGCAAGGCAGCCAATAAGAGGGTCATGGATGTGATCAACTCAGCCAGGACCCGCCAGCAGATGCTGC
ATGCCCAGACCTTCCACAGCAACTCTCTTTTGACCCAGGAAGATGCAGCAGCTGCTGGGGATCGCAGACCAGCCCCTGACACCTGGATTT
ATCCGCTGATTCAGATGAAGCCCTTCGAGATTCAAATCGATGAGATTGTCACTGAGACCCTGTTGACTGAGGCGGAGCGCGGGGCAAAGG
TCTACCTCACCACTGGCTATTTCAACCTGACCCAGGCCTACATGGACCTGGTCTTGGGCACTCGGGCTGAGTACCAGATCCTGCTGGCCT
CACCAGAGGTGAATGGCTTCTTTGGGGCCAAGGGGGTGGCCGGCGCCATCCCAGCGGCCTATGTGCACATCGAGCGACAGTTCTTCAGTG
AGGTGTGCAGCCTGGGACAGCAGGAGCGGGTCCAGCTTCAGGAGTACTGGCGGAGGGGCTGGACGTTCCACGCCAAAGAAACATCCGAAA
CTGAAATCACAACAACAGAAATAATTAAGAGGAGAGATGTTGGTCCTTATGGCATTCGATCTGAATATTGTATCAGGAAAATCATTTGTC
CCATTGGAGTTCCAGAAACACCAAAAGAAACGCCTACACCTCAGAGGAAAGGCCTTCGATCAAGTGCACTGCGGCCAAAGAGACCAGAAA
CGCCCAAGCAAACTGGCCCTGTTATTATTGAAACCTGGGTAGCAGAAGAAGAACTGGAATTGTGGGAGATCAGGGCATTTGCTGAGAGAG
TGGAGAAAGAAAAGGCACAAGCAGTTGAGCAACAGGCTAAGAAACGACTGGAGCAGCAGAAGCCGACAGTGATTGCAACTTCCACTACTT
CCCCAACAAGCAGTACAACCAGCACCATCTCTCCAGCACAGAAGGTTATGGTGGCCCCCATAAGTGGCTCAGTTACAACTGGAACCAAAA
TGGTACTAACTACTAAAGTTGGATCTCCAGCTACAGTAACATTCCAACAAAACAAGAACTTTCATCAAACCTTTGCTACATGGGTTAAGC
AAGGCCAGTCAAATTCAGGCGTTGTTCAAGTACAGCAGAAAGTCCTGGGTATCATTCCATCAAGTACAGGTACCAGTCAGCAAACCTTTA
CTTCATTCCAGCCCAGGACAGCAACAGTCACAATTAGGCCCAATACCTCAGGCTCTGGAGGAACCACAAGCAATTCACAAGTAATCACAG
GGCCTCAGATTCGCCCTGGTATGACCGTGATTAGAACACCACTCCAACAGTCAACACTAGGAAAGGCAATTATTCGAACACCTGTGATGG
TACAGCCAGGTGCTCCTCAGCAAGTGATGACTCAAATCATCAGGGGGCAGCCTGTCTCCACTGCAGTCTCCGCCCCTAACACGGTTTCCT
CAACACCTGGGCAGAAAAGCTTAACTTCAGCAACGTCCACTTCAAATATACAGTCTTCAGCCTCACAACCCCCTCGCCCCCAACAAGGAC
AAGTGAAGCTCACCATGGCTCAACTTACTCAGTTAACACAGGGCCACGGTGGCAATCAAGGTTTGACAGTAGTAATTCAAGGACAAGGTC
AAACTACTGGACAGTTGCAGTTGATACCTCAAGGGGTGACTGTACTCCCAGGCCCAGGCCAGCAGCTAATGCAAGCTGCAATGCCAAATG
GTACTGTTCAGCGATTCCTCTTTACCCCATTGGCAACAACAGCCACCACAGCCAGCACCACCACCACCACTGTTTCCACGACAGCAGCAG
GTACAGGTGAACAAAGGCAGAGTAAACTGTCACCCCAGATGCAGGTACATCAAGACAAAACCCTGCCACCAGCTCAGTCATCAAGTGTGG
GTCCAGCAGAAGCCCAGCCACAGACTGCTCAGCCTTCAGCTCAGCCCCAGCCCCAAACCCAGCCCCAGTCCCCAGCTCAGCCTGAAGTTC
AGACTCAGCCTGAAGTTCAGACCCAAACAACTGTTTCATCCCATGTCCCTTCTGAAGCACAACCCACCCACGCACAGTCATCCAAGCCCC
AAGTTGCAGCACAGTCTCAGCCTCAAAGTAATGTCCAAGGACAGTCTCCTGTTCGTGTCCAAAGTCCATCACAGACTCGAATACGTCCAT
CAACTCCATCCCAACTGTCTCCTGGACAACAATCCCAGGTTCAGACTACAACCTCACAACCGATTCCAATTCAACCACATACATCTCTTC
AGATACCTTCCCAAGGCCAGCCACAGTCACAACCCCAGGTGGTGATGAAGCATAATGCTGTAATAGAACATTTAAAACAGAAAAAGAGCA
TGACTCCAGCTGAAAGAGAAGAGAATCAAAGAATGATTGTCTGTAACCAGGTGATGAAGTATATTTTGGATAAGATAGATAAAGAAGAAA
AACAGGCAGCAAAAAAACGGAAGCGTGAAGAGAGTGTGGAGCAGAAACGTAGCAAGCAGAATGCCACTAAGCTGTCAGCTCTGCTCTTCA
AGCACAAAGAGCAGCTCAGAGCCGAGATCCTGAAGAAGAGAGCACTCCTGGACAAGGATCTGCAAATTGAAGTGCAGGAAGAGCTGAAGA
GAGACCTGAAAATTAAGAAAGAAAAAGACCTGATGCAGTTGGCTCAGGCCACAGCAGTAGCTGCACCCTGCCCCCCAGTGACACCAGCTC
CTCCAGCCCCTCCAGCCCCTCCACCTTCACCTCCCCCTCCACCTGCTGTGCAACACACAGGCCTTCTGTCCACGCCCACCTTACCTGCTG
CTTCCCAGAAGAGGAAGCGGGAAGAGGAAAAAGACTCCAGCTCAAAGTCCAAGAAAAAGAAAATGATCTCTACTACCTCAAAGGAAACTA
AGAAGGACACAAAGCTTTACTGTATCTGTAAAACGCCTTATGATGAATCTAAATTTTATATTGGCTGTGATCGGTGTCAGAATTGGTACC
ATGGGCGCTGCGTTGGCATCTTGCAAAGTGAGGCAGAGCTCATTGATGAGTATGTCTGTCCACAGTGCCAGTCAACAGAGGATGCCATGA
CAGTGCTCACGCCACTAACAGAGAAGGATTATGAGGGGTTGAAGAGGGTGCTCCGTTCCTTACAGGCCCATAAGATGGCCTGGCCTTTCC
TTGAACCAGTAGACCCTAATGATGCACCAGATTATTATGGTGTTATTAAGGAACCTATGGACCTTGCCACCATGGAAGAAAGAGTACAAA
GACGATATTATGAAAAGCTGACGGAATTTGTGGCAGATATGACCAAAATTTTTGATAACTGTCGTTACTACAATCCAAGTGACTCCCCAT
TTTACCAGTGTGCAGAAGTTCTCGAATCATTCTTTGTACAGAAATTGAAAGGCTTCAAAGCTAGCAGGTCTCATAACAACAAACTGCAGT
CTACAGCTTCTTAAAGTTCAGCGTGTTAACCTAACATAAAACACAGCAAGAATCTGGTTGTCTGAACTATTTTAAATTAAGGAGCCAGAT
GTTTTTAGTCAGGCTATCCTGACAAGACTTGACCTAAACTTCGTTTTTATTGGTCATAACAGTCCAATTATATTCTTGGCCAATTTTGTC
CAACGGACAAGAAAAAAGCAAAGTCAACGACACCATTATCTTGTCAAGATCAGATGGTTTTACTATTGTGGCAGAAGCGAGAAAACTTTG
TTTATTGAAAAAAAAAGAAAAAGAAAGCAAGAAAAAAAGATACTATGGGGTCAAGTGTAACTCCATGGAAATGCCACGTCTGCTCTTCAG
TGAAGAAGCTGGTTTAGAGTCTCACAGAAAACTTTTGACTGTATTTATTTATTGTTGCAAAAAAGACGCTTTTTTATTGCTGCCCTCATT
TGTCAGCTAATTATTTTTTCTTATAAAATCCAGCCCCGGTTACATATAATCATCTGTATCTTATCATGATTCCTGTAGGTAAAAGTACAA
GACGACCTCTAGATGTCTTTTCTTTCTATGAAAGGAGCTGCTATGTACACATGTGCACACACACACAACTGGGAATCAACAATGAGTTTA
TTGTTCATGGTAGATTAAAATTAAGCTTGCATAAAGGTTGGGCTAAGTGGTCCTGGACTACAGACTCTGTTGCCTTGAATATAACAGTAC
AATTTGTCAATTACTCTGCACCAGGCTAAAATGAGTAAAATCTATTTGAAGGTATCTTGTTTGTAAACATTTGTCAGATTCTAATTTTTT
TCTTTTGTATTAAAATTCAACTATGGATGTATATGAAACAAAATAAATGGAGATAATTTTTCTCCCACAGACAGAGGTGTCTTTGAATGT
GCGCTAATGATTATCTGTAAGCCTTTGTGGGGAGGGAGGCCTGCAAGGTCATGAAAGGCAGAAGAGTCTAATTGTGCCTGGATTTCTCCA
GGACAGCAGTGGCCCCTCGTTTTATCATTCCCAGTCCATTGTCATCACGTCAGAGAAAAATCTTCAGGGGTGCTAATCCTGTTGCATCAG
TTGATCATACTAACGAGAACGGTAATGCGACAAGATACACATTGCCTTCATCTGTACATTCTGTGATACCAGGCAAATTACCAATTACAC
ACAGCTACTTATATTTTATGAAGGGCATTTTTTAGATGACCTCATCCTCTGTGTTATTTGTTGATTGGGTTTGTTTTCTGTTTGTTGGTT
TGTTTGTTTCTTCCACGTAAGGAAAAGTAGTGTAAACAGTAGCGAGAAAATGGAAACCACAGAGGAAGATGTATTTTGCATGTTTTTCCT
TTCAGTGTTCTTACACGTTGTATCACTGCATTGTGGTAATAGCTTCTATAAAATCTGCCATAGTTGGATTATGCAGCTTTGCAAAAATTT
TTACTAGATTTTGCACTAACTCATATTAGCTTTGTCCTACCAACTTCTGGAATTTATCTAATTATTGTTTTTCAAAGTTTCTTTCCTTTT
AATGTTTCCCTGCTATGCAAAACCTTTCCCAGACCTCAGTTTCTTAAAAGAAAGATGTTGCTACAGTTCCCGATTCTTTCTTATTACAGG
CTCAGGTGTACAGGTTATTCTGGGTTAATTTTATCTAATGAAGCCCATTCCTTTTTGTACATAAAGATGTCACTTAAACTTATGCTTACA
AACTAAAGACTAATCGCTCAATATGAAAACATGAAAAAATTTTTGCTTAAAGTATTAAGATGGAAGTAGTTAAATATGGGTTATTTTGTC
CTTTTACTTTTTTAAAAAATGTTACATATTGTATGCACTGTGCTGATGCAAGAATTCTACATTTTAATGAGTTATAAAATTATTCTGCAT
CTCATCACGTCACAGTATTTCTGTACTATTTATTCATATATATAAATATATATGGGCTTAATCATTTAAAATTTGTTGCAGCAAGAACTT
TCCTACCTGTAGGCAATAGATTGCTATGTTTTTAACAAATTGTGGCAAATTCTAAACAGCAATTCTTTTGTACGTAATAGGACATTTCAT

>64664_64664_3_PGS1-BPTF_PGS1_chr17_76400170_ENST00000262764_BPTF_chr17_65916130_ENST00000335221_length(amino acids)=1435AA_BP=467
MAVAAAAAAGPVFWRRLLGLLPGRPGLAALLGRLSDRLGRNRDRQRRRSPWLLLAPLLSPAVPQVTSPPCCLCPEGVHRFQWIRNLVPEF
GVSSSHVRVLSSPAEFFELMKGQIRVAKRRVVMASLYLGTGPLEQELVDCLESTLEKSLQAKFPSNLKVSILLDFTRGSRGRKNSRTMLL
PLLRRFPEQVRVSLFHTPHLRGLLRLLIPERFNETIGLQHIKVYLFDNSVILSGANLSDSYFTNRQDRYVFLQDCAEIADFFTELVDAVG
DVSLQLQGDDTVQVVDGMVHPYKGDRAEYCKAANKRVMDVINSARTRQQMLHAQTFHSNSLLTQEDAAAAGDRRPAPDTWIYPLIQMKPF
EIQIDEIVTETLLTEAERGAKVYLTTGYFNLTQAYMDLVLGTRAEYQILLASPEVNGFFGAKGVAGAIPAAYVHIERQFFSEVCSLGQQE
RVQLQEYWRRGWTFHAKETSETEITTTEIIKRRDVGPYGIRSEYCIRKIICPIGVPETPKETPTPQRKGLRSSALRPKRPETPKQTGPVI
IETWVAEEELELWEIRAFAERVEKEKAQAVEQQAKKRLEQQKPTVIATSTTSPTSSTTSTISPAQKVMVAPISGSVTTGTKMVLTTKVGS
PATVTFQQNKNFHQTFATWVKQGQSNSGVVQVQQKVLGIIPSSTGTSQQTFTSFQPRTATVTIRPNTSGSGGTTSNSQVITGPQIRPGMT
VIRTPLQQSTLGKAIIRTPVMVQPGAPQQVMTQIIRGQPVSTAVSAPNTVSSTPGQKSLTSATSTSNIQSSASQPPRPQQGQVKLTMAQL
TQLTQGHGGNQGLTVVIQGQGQTTGQLQLIPQGVTVLPGPGQQLMQAAMPNGTVQRFLFTPLATTATTASTTTTTVSTTAAGTGEQRQSK
LSPQMQVHQDKTLPPAQSSSVGPAEAQPQTAQPSAQPQPQTQPQSPAQPEVQTQPEVQTQTTVSSHVPSEAQPTHAQSSKPQVAAQSQPQ
SNVQGQSPVRVQSPSQTRIRPSTPSQLSPGQQSQVQTTTSQPIPIQPHTSLQIPSQGQPQSQPQVVMKHNAVIEHLKQKKSMTPAEREEN
QRMIVCNQVMKYILDKIDKEEKQAAKKRKREESVEQKRSKQNATKLSALLFKHKEQLRAEILKKRALLDKDLQIEVQEELKRDLKIKKEK
DLMQLAQATAVAAPCPPVTPAPPAPPAPPPSPPPPPAVQHTGLLSTPTLPAASQKRKREEEKDSSSKSKKKKMISTTSKETKKDTKLYCI
CKTPYDESKFYIGCDRCQNWYHGRCVGILQSEAELIDEYVCPQCQSTEDAMTVLTPLTEKDYEGLKRVLRSLQAHKMAWPFLEPVDPNDA

--------------------------------------------------------------
>64664_64664_4_PGS1-BPTF_PGS1_chr17_76400170_ENST00000262764_BPTF_chr17_65916130_ENST00000424123_length(transcript)=4334nt_BP=1428nt
AGCGGAAGCGGAAGCGGCGAGTCTCCATGGCGGTGGCGGCGGCAGCTGCGGCGGGACCCGTGTTCTGGAGGCGACTGCTGGGCCTCCTGC
CTGGCCGCCCAGGGCTGGCCGCGCTCCTGGGACGCCTGTCCGACCGCCTCGGCAGGAACCGGGACCGCCAGCGCAGGAGGTCACCATGGC
TGTTATTGGCTCCCTTGCTGTCCCCAGCTGTTCCCCAGGTCACCTCCCCACCTTGCTGCCTGTGTCCAGAAGGCGTGCACCGGTTCCAGT
GGATCAGAAACCTGGTTCCAGAATTTGGAGTCTCCAGTTCTCACGTTAGGGTGCTTTCTTCCCCGGCAGAGTTTTTCGAGCTCATGAAGG
GGCAGATAAGAGTAGCCAAGAGGCGGGTCGTGATGGCATCCCTCTACCTGGGGACAGGTCCTTTGGAACAGGAGCTGGTGGACTGCCTGG
AAAGTACTCTAGAAAAGTCACTCCAAGCAAAGTTTCCTTCAAATCTCAAGGTCTCCATTCTCTTAGACTTCACGCGGGGCTCACGAGGCC
GGAAGAACTCCCGCACAATGCTGCTCCCACTCCTGCGGAGGTTCCCAGAGCAGGTCCGAGTCTCCCTCTTTCACACGCCGCACCTCCGTG
GGCTGCTTCGGCTCCTCATCCCTGAGCGCTTCAACGAGACCATCGGCCTCCAGCACATTAAGGTGTACCTCTTCGACAACAGCGTCATCT
TGAGCGGTGCAAACCTGAGTGACTCCTACTTCACCAACCGCCAGGACCGCTACGTGTTCCTGCAGGACTGTGCGGAGATTGCCGACTTCT
TCACGGAGCTGGTGGACGCGGTGGGGGATGTGTCCCTGCAGCTGCAGGGGGACGACACGGTGCAGGTGGTGGATGGGATGGTGCATCCTT
ACAAAGGGGACCGGGCCGAGTACTGCAAGGCAGCCAATAAGAGGGTCATGGATGTGATCAACTCAGCCAGGACCCGCCAGCAGATGCTGC
ATGCCCAGACCTTCCACAGCAACTCTCTTTTGACCCAGGAAGATGCAGCAGCTGCTGGGGATCGCAGACCAGCCCCTGACACCTGGATTT
ATCCGCTGATTCAGATGAAGCCCTTCGAGATTCAAATCGATGAGATTGTCACTGAGACCCTGTTGACTGAGGCGGAGCGCGGGGCAAAGG
TCTACCTCACCACTGGCTATTTCAACCTGACCCAGGCCTACATGGACCTGGTCTTGGGCACTCGGGCTGAGTACCAGATCCTGCTGGCCT
CACCAGAGGTGAATGGCTTCTTTGGGGCCAAGGGGGTGGCCGGCGCCATCCCAGCGGCCTATGTGCACATCGAGCGACAGTTCTTCAGTG
AGGTGTGCAGCCTGGGACAGCAGGAGCGGGTCCAGCTTCAGGAGTACTGGCGGAGGGGCTGGACGTTCCACGCCAAAGAAACATCCGAAA
CTGAAATCACAACAACAGAAATAATTAAGAGGAGAGATGTTGGTCCTTATGGCATTCGATCTGAATATTGTATCAGGAAAATCATTTGTC
CCATTGGAGTTCCAGAAACACCAAAAGAAACGCCTACACCTCAGAGGAAAGGCCTTCGATCAAGTGCACTGCGGCCAAAGAGACCAGAAA
CGCCCAAGCAAACTGGCCCTGTTATTATTGAAACCTGGGTAGCAGAAGAAGAACTGGAATTGTGGGAGATCAGGGCATTTGCTGAGAGAG
TGGAGAAAGAAAAGGCACAAGCAGTTGAGCAACAGGCTAAGAAACGACTGGAGCAGCAGAAGCCGACAGTGATTGCAACTTCCACTACTT
CCCCAACAAGCAGTACAACCAGCACCATCTCTCCAGCACAGAAGGTTATGGTGGCCCCCATAAGTGGCTCAGTTACAACTGGAACCAAAA
TGGTACTAACTACTAAAGTTGGATCTCCAGCTACAGTAACATTCCAACAAAACAAGAACTTTCATCAAACCTTTGCTACATGGGTTAAGC
AAGGCCAGTCAAATTCAGGCGTTGTTCAAGTACAGCAGAAAGTCCTGGGTATCATTCCATCAAGTACAGGTACCAGTCAGCAAACCTTTA
CTTCATTCCAGCCCAGGACAGCAACAGTCACAATTAGGCCCAATACCTCAGGCTCTGGAGGAACCACAAGCAATTCACAAGTAATCACAG
GGCCTCAGATTCGCCCTGGTATGACCGTGATTAGAACACCACTCCAACAGTCAACACTAGGAAAGGCAATTATTCGAACACCTGTGATGG
TACAGCCAGGTGCTCCTCAGCAAGTGATGACTCAAATCATCAGGGGGCAGCCTGTCTCCACTGCAGTCTCCGCCCCTAACACGGTTTCCT
CAACACCTGGGCAGAAAAGCTTAACTTCAGCAACGTCCACTTCAAATATACAGTCTTCAGCCTCACAACCCCCTCGCCCCCAACAAGGAC
AAGTGAAGCTCACCATGGCTCAACTTACTCAGTTAACACAGGGCCACGGTGGCAATCAAGGTTTGACAGTAGTAATTCAAGGACAAGGTC
AAACTACTGGACAGTTGCAGTTGATACCTCAAGGGGTGACTGTACTCCCAGGCCCAGGCCAGCAGCTAATGCAAGCTGCAATGCCAAATG
GTACTGTTCAGCGATTCCTCTTTACCCCATTGGCAACAACAGCCACCACAGCCAGCACCACCACCACCACTGTTTCCACGACAGCAGCAG
GTACAGGTGAACAAAGGCAGAGTAAACTGTCACCCCAGATGCAGGTACATCAAGACAAAACCCTGCCACCAGCTCAGTCATCAAGTGTGG
GTCCAGCAGAAGCCCAGCCACAGACTGCTCAGCCTTCAGCTCAGCCCCAGCCCCAAACCCAGCCCCAGTCCCCAGCTCAGCCTGAAGTTC
AGACTCAGCCTGAAGTTCAGACCCAAACAACTGTTTCATCCCATGTCCCTTCTGAAGCACAACCCACCCACGCACAGTCATCCAAGCCCC
AAGTTGCAGCACAGTCTCAGCCTCAAAGTAATGTCCAAGGACAGTCTCCTGTTCGTGTCCAAAGTCCATCACAGACTCGAATACGTCCAT
CAACTCCATCCCAACTGTCTCCTGGACAACAATCCCAGGTTCAGACTACAACCTCACAACCGATTCCAATTCAACCACATACATCTCTTC
AGATACCTTCCCAAGGCCAGCCACAGTCACAACCCCAGGTGGTGATGAAGCATAATGCTGTAATAGAACATTTAAAACAGAAAAAGAGCA
TGACTCCAGCTGAAAGAGAAGAGAATCAAAGAATGATTGTCTGTAACCAGGTGATGAAGTATATTTTGGATAAGATAGATAAAGAAGAAA
AACAGGCAGCAAAAAAACGGAAGCGTGAAGAGAGTGTGGAGCAGAAACGTAGCAAGCAGAATGCCACTAAGCTGTCAGCTCTGCTCTTCA
AGCACAAAGAGCAGCTCAGAGCCGAGATCCTGAAGAAGAGAGCACTCCTGGACAAGGATCTGCAAATTGAAGTGCAGGAAGAGCTGAAGA
GAGACCTGAAAATTAAGAAAGAAAAAGACCTGATGCAGTTGGCTCAGGCCACAGCAGTAGCTGCACCCTGCCCCCCAGTGACACCAGCTC
CTCCAGCCCCTCCAGCCCCTCCACCTTCACCTCCCCCTCCACCTGCTGTGCAACACACAGGCCTTCTGTCCACGCCCACCTTACCTGCTG
CTTCCCAGAAGAGGAAGCGGGAAGAGGAAAAAGACTCCAGCTCAAAGTCCAAGAAAAAGAAAATGATCTCTACTACCTCAAAGGAAACTA
AGAAGGACACAAAGCTTTACTGTATCTGTAAAACGCCTTATGATGAATCTAAATTTTATATTGGCTGTGATCGGTGTCAGAATTGGTACC
ATGGGCGCTGCGTTGGCATCTTGCAAAGTGAGGCAGAGCTCATTGATGAGTATGTCTGTCCACAGTGCCAGTCAACAGAGGATGCCATGA
CAGTGCTCACGCCACTAACAGAGAAGGATTATGAGGGGTTGAAGAGGGTGCTCCGTTCCTTACAGGCCCATAAGATGGCCTGGCCTTTCC
TTGAACCAGTAGACCCTAATGATGCACCAGATTATTATGGTGTTATTAAGGAACCTATGGACCTTGCCACCATGGAAGAAAGAGTACAAA
GACGATATTATGAAAAGCTGACGGAATTTGTGGCAGATATGACCAAAATTTTTGATAACTGTCGTTACTACAATCCAAGTGACTCCCCAT
TTTACCAGTGTGCAGAAGTTCTCGAATCATTCTTTGTACAGAAATTGAAAGGCTTCAAAGCTAGCAGGTCTCATAACAACAAACTGCAGT

>64664_64664_4_PGS1-BPTF_PGS1_chr17_76400170_ENST00000262764_BPTF_chr17_65916130_ENST00000424123_length(amino acids)=1436AA_BP=467
MAVAAAAAAGPVFWRRLLGLLPGRPGLAALLGRLSDRLGRNRDRQRRRSPWLLLAPLLSPAVPQVTSPPCCLCPEGVHRFQWIRNLVPEF
GVSSSHVRVLSSPAEFFELMKGQIRVAKRRVVMASLYLGTGPLEQELVDCLESTLEKSLQAKFPSNLKVSILLDFTRGSRGRKNSRTMLL
PLLRRFPEQVRVSLFHTPHLRGLLRLLIPERFNETIGLQHIKVYLFDNSVILSGANLSDSYFTNRQDRYVFLQDCAEIADFFTELVDAVG
DVSLQLQGDDTVQVVDGMVHPYKGDRAEYCKAANKRVMDVINSARTRQQMLHAQTFHSNSLLTQEDAAAAGDRRPAPDTWIYPLIQMKPF
EIQIDEIVTETLLTEAERGAKVYLTTGYFNLTQAYMDLVLGTRAEYQILLASPEVNGFFGAKGVAGAIPAAYVHIERQFFSEVCSLGQQE
RVQLQEYWRRGWTFHAKETSETEITTTEIIKRRDVGPYGIRSEYCIRKIICPIGVPETPKETPTPQRKGLRSSALRPKRPETPKQTGPVI
IETWVAEEELELWEIRAFAERVEKEKAQAVEQQAKKRLEQQKPTVIATSTTSPTSSTTSTISPAQKVMVAPISGSVTTGTKMVLTTKVGS
PATVTFQQNKNFHQTFATWVKQGQSNSGVVQVQQKVLGIIPSSTGTSQQTFTSFQPRTATVTIRPNTSGSGGTTSNSQVITGPQIRPGMT
VIRTPLQQSTLGKAIIRTPVMVQPGAPQQVMTQIIRGQPVSTAVSAPNTVSSTPGQKSLTSATSTSNIQSSASQPPRPQQGQVKLTMAQL
TQLTQGHGGNQGLTVVIQGQGQTTGQLQLIPQGVTVLPGPGQQLMQAAMPNGTVQRFLFTPLATTATTASTTTTTVSTTAAGTGEQRQSK
LSPQMQVHQDKTLPPAQSSSVGPAEAQPQTAQPSAQPQPQTQPQSPAQPEVQTQPEVQTQTTVSSHVPSEAQPTHAQSSKPQVAAQSQPQ
SNVQGQSPVRVQSPSQTRIRPSTPSQLSPGQQSQVQTTTSQPIPIQPHTSLQIPSQGQPQSQPQVVMKHNAVIEHLKQKKSMTPAEREEN
QRMIVCNQVMKYILDKIDKEEKQAAKKRKREESVEQKRSKQNATKLSALLFKHKEQLRAEILKKRALLDKDLQIEVQEELKRDLKIKKEK
DLMQLAQATAVAAPCPPVTPAPPAPPAPPPSPPPPPAVQHTGLLSTPTLPAASQKRKREEEKDSSSKSKKKKMISTTSKETKKDTKLYCI
CKTPYDESKFYIGCDRCQNWYHGRCVGILQSEAELIDEYVCPQCQSTEDAMTVLTPLTEKDYEGLKRVLRSLQAHKMAWPFLEPVDPNDA

--------------------------------------------------------------
>64664_64664_5_PGS1-BPTF_PGS1_chr17_76400170_ENST00000262764_BPTF_chr17_65916131_ENST00000306378_length(transcript)=5628nt_BP=1428nt
AGCGGAAGCGGAAGCGGCGAGTCTCCATGGCGGTGGCGGCGGCAGCTGCGGCGGGACCCGTGTTCTGGAGGCGACTGCTGGGCCTCCTGC
CTGGCCGCCCAGGGCTGGCCGCGCTCCTGGGACGCCTGTCCGACCGCCTCGGCAGGAACCGGGACCGCCAGCGCAGGAGGTCACCATGGC
TGTTATTGGCTCCCTTGCTGTCCCCAGCTGTTCCCCAGGTCACCTCCCCACCTTGCTGCCTGTGTCCAGAAGGCGTGCACCGGTTCCAGT
GGATCAGAAACCTGGTTCCAGAATTTGGAGTCTCCAGTTCTCACGTTAGGGTGCTTTCTTCCCCGGCAGAGTTTTTCGAGCTCATGAAGG
GGCAGATAAGAGTAGCCAAGAGGCGGGTCGTGATGGCATCCCTCTACCTGGGGACAGGTCCTTTGGAACAGGAGCTGGTGGACTGCCTGG
AAAGTACTCTAGAAAAGTCACTCCAAGCAAAGTTTCCTTCAAATCTCAAGGTCTCCATTCTCTTAGACTTCACGCGGGGCTCACGAGGCC
GGAAGAACTCCCGCACAATGCTGCTCCCACTCCTGCGGAGGTTCCCAGAGCAGGTCCGAGTCTCCCTCTTTCACACGCCGCACCTCCGTG
GGCTGCTTCGGCTCCTCATCCCTGAGCGCTTCAACGAGACCATCGGCCTCCAGCACATTAAGGTGTACCTCTTCGACAACAGCGTCATCT
TGAGCGGTGCAAACCTGAGTGACTCCTACTTCACCAACCGCCAGGACCGCTACGTGTTCCTGCAGGACTGTGCGGAGATTGCCGACTTCT
TCACGGAGCTGGTGGACGCGGTGGGGGATGTGTCCCTGCAGCTGCAGGGGGACGACACGGTGCAGGTGGTGGATGGGATGGTGCATCCTT
ACAAAGGGGACCGGGCCGAGTACTGCAAGGCAGCCAATAAGAGGGTCATGGATGTGATCAACTCAGCCAGGACCCGCCAGCAGATGCTGC
ATGCCCAGACCTTCCACAGCAACTCTCTTTTGACCCAGGAAGATGCAGCAGCTGCTGGGGATCGCAGACCAGCCCCTGACACCTGGATTT
ATCCGCTGATTCAGATGAAGCCCTTCGAGATTCAAATCGATGAGATTGTCACTGAGACCCTGTTGACTGAGGCGGAGCGCGGGGCAAAGG
TCTACCTCACCACTGGCTATTTCAACCTGACCCAGGCCTACATGGACCTGGTCTTGGGCACTCGGGCTGAGTACCAGATCCTGCTGGCCT
CACCAGAGGTGAATGGCTTCTTTGGGGCCAAGGGGGTGGCCGGCGCCATCCCAGCGGCCTATGTGCACATCGAGCGACAGTTCTTCAGTG
AGGTGTGCAGCCTGGGACAGCAGGAGCGGGTCCAGCTTCAGGAGTACTGGCGGAGGGGCTGGACGTTCCACGCCAAAGAAACATCCGAAA
CTGAAATCACAACAACAGAAATAATTAAGAGGAGAGATGTTGGTCCTTATGGCATTCGATCTGAATATTGTATCAGGAAAATCATTTGTC
CCATTGGAGTTCCAGAAACACCAAAAGAAACGCCTACACCTCAGAGGAAAGGCCTTCGATCAAGTGCACTGCGGCCAAAGAGACCAGAAA
CGCCCAAGCAAACTGGCCCTGTTATTATTGAAACCTGGGTAGCAGAAGAAGAACTGGAATTGTGGGAGATCAGGGCATTTGCTGAGAGAG
TGGAGAAAGAAAAGGCACAAGCAGTTGAGCAACAGGCTAAGAAACGACTGGAGCAGCAGAAGCCGACAGTGATTGCAACTTCCACTACTT
CCCCAACAAGCAGTACAACCAGCACCATCTCTCCAGCACAGAAGGTTATGGTGGCCCCCATAAGTGGCTCAGTTACAACTGGAACCAAAA
TGGTACTAACTACTAAAGTTGGATCTCCAGCTACAGTAACATTCCAACAAAACAAGAACTTTCATCAAACCTTTGCTACATGGGTTAAGC
AAGGCCAGTCAAATTCAGGCGTTGTTCAAGTACAGCAGAAAGTCCTGGGTATCATTCCATCAAGTACAGGTACCAGTCAGCAAACCTTTA
CTTCATTCCAGCCCAGGACAGCAACAGTCACAATTAGGCCCAATACCTCAGGCTCTGGAGGAACCACAAGCAATTCACAAGTAATCACAG
GGCCTCAGATTCGCCCTGGTATGACCGTGATTAGAACACCACTCCAACAGTCAACACTAGGAAAGGCAATTATTCGAACACCTGTGATGG
TACAGCCAGGTGCTCCTCAGCAAGTGATGACTCAAATCATCAGGGGGCAGCCTGTCTCCACTGCAGTCTCCGCCCCTAACACGGTTTCCT
CAACACCTGGGCAGAAAAGCTTAACTTCAGCAACGTCCACTTCAAATATACAGTCTTCAGCCTCACAACCCCCTCGCCCCCAACAAGGAC
AAGTGAAGCTCACCATGGCTCAACTTACTCAGTTAACACAGGGCCACGGTGGCAATCAAGGTTTGACAGTAGTAATTCAAGGACAAGGTC
AAACTACTGGACAGTTGCAGTTGATACCTCAAGGGGTGACTGTACTCCCAGGCCCAGGCCAGCAGCTAATGCAAGCTGCAATGCCAAATG
GTACTGTTCAGCGATTCCTCTTTACCCCATTGGCAACAACAGCCACCACAGCCAGCACCACCACCACCACTGTTTCCACGACAGCAGCAG
GTACAGGTGAACAAAGGCAGAGTAAACTGTCACCCCAGATGCAGGTACATCAAGACAAAACCCTGCCACCAGCTCAGTCATCAAGTGTGG
GTCCAGCAGAAGCCCAGCCACAGACTGCTCAGCCTTCAGCTCAGCCCCAGCCCCAAACCCAGCCCCAGTCCCCAGCTCAGCCTGAAGTTC
AGACTCAGCCTGAAGTTCAGACCCAAACAACTGTTTCATCCCATGTCCCTTCTGAAGCACAACCCACCCACGCACAGTCATCCAAGCCCC
AAGTTGCAGCACAGTCTCAGCCTCAAAGTAATGTCCAAGGACAGTCTCCTGTTCGTGTCCAAAGTCCATCACAGACTCGAATACGTCCAT
CAACTCCATCCCAACTGTCTCCTGGACAACAATCCCAGGTTCAGACTACAACCTCACAACCGATTCCAATTCAACCACATACATCTCTTC
AGATACCTTCCCAAGGCCAGCCACAGTCACAACCCCAGGTACAGTCTTCAACTCAAACTCTTTCATCAGGACAAACTTTAAATCAAGTTA
CTGTTTCATCCCCATCCCGTCCTCAGCTACAAATACAGCAGCCACAGCCCCAAGTCATTGCTGTGCCTCAGCTGCAACAACAAGTCCAGG
TTCTCTCTCAGATCCAGTCACAGGTTGTGGCTCAGATACAGGCTCAGCAAAGTGGTGTGCCCCAGCAAATCAAACTCCAGTTACCTATCC
AAATTCAGCAAAGCAGTGCTGTGCAGACTCACCAGATTCAGAATGTGGTTACAGTGCAGGCAGCCAGTGTGCAAGAGCAGTTGCAAAGGG
TTCAGCAACTCAGGGATCAGCAGCAAAAGAAGAAACAGCAACAGATAGAAATTAAGCGTGAACACACCCTCCAAGCTTCTAATCAAAGTG
AAATCATTCAGAAACAGGTGGTGATGAAGCATAATGCTGTAATAGAACATTTAAAACAGAAAAAGAGCATGACTCCAGCTGAAAGAGAAG
AGAATCAAAGAATGATTGTCTGTAACCAGGTGATGAAGTATATTTTGGATAAGATAGATAAAGAAGAAAAACAGGCAGCAAAAAAACGGA
AGCGTGAAGAGAGTGTGGAGCAGAAACGTAGCAAGCAGAATGCCACTAAGCTGTCAGCTCTGCTCTTCAAGCACAAAGAGCAGCTCAGAG
CCGAGATCCTGAAGAAGAGAGCACTCCTGGACAAGGATCTGCAAATTGAAGTGCAGGAAGAGCTGAAGAGAGACCTGAAAATTAAGAAAG
AAAAAGACCTGATGCAGTTGGCTCAGGCCACAGCAGTAGCTGCACCCTGCCCCCCAGTGACACCAGCTCCTCCAGCCCCTCCAGCCCCTC
CACCTTCACCTCCCCCTCCACCTGCTGTGCAACACACAGGCCTTCTGTCCACGCCCACCTTACCTGCTGCTTCCCAGAAGAGGAAGCGGG
AAGAGGAAAAAGACTCCAGCTCAAAGTCCAAGAAAAAGAAAATGATCTCTACTACCTCAAAGGAAACTAAGAAGGACACAAAGCTTTACT
GTATCTGTAAAACGCCTTATGATGAATCTAAATTTTATATTGGCTGTGATCGGTGTCAGAATTGGTACCATGGGCGCTGCGTTGGCATCT
TGCAAAGTGAGGCAGAGCTCATTGATGAGTATGTCTGTCCACAGTGCCAGTCAACAGAGGATGCCATGACAGTGCTCACGCCACTAACAG
AGAAGGATTATGAGGGGTTGAAGAGGGTGCTCCGTTCCTTACAGGCCCATAAGATGGCCTGGCCTTTCCTTGAACCAGTAGACCCTAATG
ATGCACCAGATTATTATGGTGTTATTAAGGAACCTATGGACCTTGCCACCATGGAAGAAAGAGTACAAAGACGATATTATGAAAAGCTGA
CGGAATTTGTGGCAGATATGACCAAAATTTTTGATAACTGTCGTTACTACAATCCAAGTGACTCCCCATTTTACCAGTGTGCAGAAGTTC
TCGAATCATTCTTTGTACAGAAATTGAAAGGCTTCAAAGCTAGCAGGTCTCATAACAACAAACTGCAGTCTACAGCTTCTTAAAGTTCAG
CGTGTTAACCTAACATAAAACACAGCAAGAATCTGGTTGTCTGAACTATTTTAAATTAAGGAGCCAGATGTTTTTAGTCAGGCTATCCTG
ACAAGACTTGACCTAAACTTCGTTTTTATTGGTCATAACAGTCCAATTATATTCTTGGCCAATTTTGTCCAACGGACAAGAAAAAAGCAA
AGTCAACGACACCATTATCTTGTCAAGATCAGATGGTTTTACTATTGTGGCAGAAGCGAGAAAACTTTGTTTATTGAAAAAAAAAGAAAA
AGAAAGCAAGAAAAAAAGATACTATGGGGTCAAGTGTAACTCCATGGAAATGCCACGTCTGCTCTTCAGTGAAGAAGCTGGTTTAGAGTC
TCACAGAAAACTTTTGACTGTATTTATTTATTGTTGCAAAAAAGACGCTTTTTTATTGCTGCCCTCATTTGTCAGCTAATTATTTTTTCT
TATAAAATCCAGCCCCGGTTACATATAATCATCTGTATCTTATCATGATTCCTGTAGGTAAAAGTACAAGACGACCTCTAGATGTCTTTT
CTTTCTATGAAAGGAGCTGCTATGTACACATGTGCACACACACACAACTGGGAATCAACAATGAGTTTATTGTTCATGGTAGATTAAAAT
TAAGCTTGCATAAAGGTTGGGCTAAGTGGTCCTGGACTACAGACTCTGTTGCCTTGAATATAACAGTACAATTTGTCAATTACTCTGCAC
CAGGCTAAAATGAGTAAAATCTATTTGAAGGTATCTTGTTTGTAAACATTTGTCAGATTCTAATTTTTTTCTTTTGTATTAAAATTCAAC

>64664_64664_5_PGS1-BPTF_PGS1_chr17_76400170_ENST00000262764_BPTF_chr17_65916131_ENST00000306378_length(amino acids)=1578AA_BP=467
MAVAAAAAAGPVFWRRLLGLLPGRPGLAALLGRLSDRLGRNRDRQRRRSPWLLLAPLLSPAVPQVTSPPCCLCPEGVHRFQWIRNLVPEF
GVSSSHVRVLSSPAEFFELMKGQIRVAKRRVVMASLYLGTGPLEQELVDCLESTLEKSLQAKFPSNLKVSILLDFTRGSRGRKNSRTMLL
PLLRRFPEQVRVSLFHTPHLRGLLRLLIPERFNETIGLQHIKVYLFDNSVILSGANLSDSYFTNRQDRYVFLQDCAEIADFFTELVDAVG
DVSLQLQGDDTVQVVDGMVHPYKGDRAEYCKAANKRVMDVINSARTRQQMLHAQTFHSNSLLTQEDAAAAGDRRPAPDTWIYPLIQMKPF
EIQIDEIVTETLLTEAERGAKVYLTTGYFNLTQAYMDLVLGTRAEYQILLASPEVNGFFGAKGVAGAIPAAYVHIERQFFSEVCSLGQQE
RVQLQEYWRRGWTFHAKETSETEITTTEIIKRRDVGPYGIRSEYCIRKIICPIGVPETPKETPTPQRKGLRSSALRPKRPETPKQTGPVI
IETWVAEEELELWEIRAFAERVEKEKAQAVEQQAKKRLEQQKPTVIATSTTSPTSSTTSTISPAQKVMVAPISGSVTTGTKMVLTTKVGS
PATVTFQQNKNFHQTFATWVKQGQSNSGVVQVQQKVLGIIPSSTGTSQQTFTSFQPRTATVTIRPNTSGSGGTTSNSQVITGPQIRPGMT
VIRTPLQQSTLGKAIIRTPVMVQPGAPQQVMTQIIRGQPVSTAVSAPNTVSSTPGQKSLTSATSTSNIQSSASQPPRPQQGQVKLTMAQL
TQLTQGHGGNQGLTVVIQGQGQTTGQLQLIPQGVTVLPGPGQQLMQAAMPNGTVQRFLFTPLATTATTASTTTTTVSTTAAGTGEQRQSK
LSPQMQVHQDKTLPPAQSSSVGPAEAQPQTAQPSAQPQPQTQPQSPAQPEVQTQPEVQTQTTVSSHVPSEAQPTHAQSSKPQVAAQSQPQ
SNVQGQSPVRVQSPSQTRIRPSTPSQLSPGQQSQVQTTTSQPIPIQPHTSLQIPSQGQPQSQPQVQSSTQTLSSGQTLNQVTVSSPSRPQ
LQIQQPQPQVIAVPQLQQQVQVLSQIQSQVVAQIQAQQSGVPQQIKLQLPIQIQQSSAVQTHQIQNVVTVQAASVQEQLQRVQQLRDQQQ
KKKQQQIEIKREHTLQASNQSEIIQKQVVMKHNAVIEHLKQKKSMTPAEREENQRMIVCNQVMKYILDKIDKEEKQAAKKRKREESVEQK
RSKQNATKLSALLFKHKEQLRAEILKKRALLDKDLQIEVQEELKRDLKIKKEKDLMQLAQATAVAAPCPPVTPAPPAPPAPPPSPPPPPA
VQHTGLLSTPTLPAASQKRKREEEKDSSSKSKKKKMISTTSKETKKDTKLYCICKTPYDESKFYIGCDRCQNWYHGRCVGILQSEAELID
EYVCPQCQSTEDAMTVLTPLTEKDYEGLKRVLRSLQAHKMAWPFLEPVDPNDAPDYYGVIKEPMDLATMEERVQRRYYEKLTEFVADMTK

--------------------------------------------------------------
>64664_64664_6_PGS1-BPTF_PGS1_chr17_76400170_ENST00000262764_BPTF_chr17_65916131_ENST00000321892_length(transcript)=6853nt_BP=1428nt
AGCGGAAGCGGAAGCGGCGAGTCTCCATGGCGGTGGCGGCGGCAGCTGCGGCGGGACCCGTGTTCTGGAGGCGACTGCTGGGCCTCCTGC
CTGGCCGCCCAGGGCTGGCCGCGCTCCTGGGACGCCTGTCCGACCGCCTCGGCAGGAACCGGGACCGCCAGCGCAGGAGGTCACCATGGC
TGTTATTGGCTCCCTTGCTGTCCCCAGCTGTTCCCCAGGTCACCTCCCCACCTTGCTGCCTGTGTCCAGAAGGCGTGCACCGGTTCCAGT
GGATCAGAAACCTGGTTCCAGAATTTGGAGTCTCCAGTTCTCACGTTAGGGTGCTTTCTTCCCCGGCAGAGTTTTTCGAGCTCATGAAGG
GGCAGATAAGAGTAGCCAAGAGGCGGGTCGTGATGGCATCCCTCTACCTGGGGACAGGTCCTTTGGAACAGGAGCTGGTGGACTGCCTGG
AAAGTACTCTAGAAAAGTCACTCCAAGCAAAGTTTCCTTCAAATCTCAAGGTCTCCATTCTCTTAGACTTCACGCGGGGCTCACGAGGCC
GGAAGAACTCCCGCACAATGCTGCTCCCACTCCTGCGGAGGTTCCCAGAGCAGGTCCGAGTCTCCCTCTTTCACACGCCGCACCTCCGTG
GGCTGCTTCGGCTCCTCATCCCTGAGCGCTTCAACGAGACCATCGGCCTCCAGCACATTAAGGTGTACCTCTTCGACAACAGCGTCATCT
TGAGCGGTGCAAACCTGAGTGACTCCTACTTCACCAACCGCCAGGACCGCTACGTGTTCCTGCAGGACTGTGCGGAGATTGCCGACTTCT
TCACGGAGCTGGTGGACGCGGTGGGGGATGTGTCCCTGCAGCTGCAGGGGGACGACACGGTGCAGGTGGTGGATGGGATGGTGCATCCTT
ACAAAGGGGACCGGGCCGAGTACTGCAAGGCAGCCAATAAGAGGGTCATGGATGTGATCAACTCAGCCAGGACCCGCCAGCAGATGCTGC
ATGCCCAGACCTTCCACAGCAACTCTCTTTTGACCCAGGAAGATGCAGCAGCTGCTGGGGATCGCAGACCAGCCCCTGACACCTGGATTT
ATCCGCTGATTCAGATGAAGCCCTTCGAGATTCAAATCGATGAGATTGTCACTGAGACCCTGTTGACTGAGGCGGAGCGCGGGGCAAAGG
TCTACCTCACCACTGGCTATTTCAACCTGACCCAGGCCTACATGGACCTGGTCTTGGGCACTCGGGCTGAGTACCAGATCCTGCTGGCCT
CACCAGAGGTGAATGGCTTCTTTGGGGCCAAGGGGGTGGCCGGCGCCATCCCAGCGGCCTATGTGCACATCGAGCGACAGTTCTTCAGTG
AGGTGTGCAGCCTGGGACAGCAGGAGCGGGTCCAGCTTCAGGAGTACTGGCGGAGGGGCTGGACGTTCCACGCCAAAGAAACATCCGAAA
CTGAAATCACAACAACAGAAATAATTAAGAGGAGAGATGTTGGTCCTTATGGCATTCGATCTGAATATTGTATCAGGAAAATCATTTGTC
CCATTGGAGTTCCAGAAACACCAAAAGAAACGCCTACACCTCAGAGGAAAGGCCTTCGATCAAGTGCACTGCGGCCAAAGAGACCAGAAA
CGCCCAAGCAAACTGGCCCTGTTATTATTGAAACCTGGGTAGCAGAAGAAGAACTGGAATTGTGGGAGATCAGGGCATTTGCTGAGAGAG
TGGAGAAAGAAAAGGCACAAGCAGTTGAGCAACAGGCTAAGAAACGACTGGAGCAGCAGAAGCCGACAGTGATTGCAACTTCCACTACTT
CCCCAACAAGCAGTACAACCAGCACCATCTCTCCAGCACAGAAGGTTATGGTGGCCCCCATAAGTGGCTCAGTTACAACTGGAACCAAAA
TGGTACTAACTACTAAAGTTGGATCTCCAGCTACAGTAACATTCCAACAAAACAAGAACTTTCATCAAACCTTTGCTACATGGGTTAAGC
AAGGCCAGTCAAATTCAGGCGTTGTTCAAGTACAGCAGAAAGTCCTGGGTATCATTCCATCAAGTACAGGTACCAGTCAGCAAACCTTTA
CTTCATTCCAGCCCAGGACAGCAACAGTCACAATTAGGCCCAATACCTCAGGCTCTGGAGGAACCACAAGCAATTCACAAGTAATCACAG
GGCCTCAGATTCGCCCTGGTATGACCGTGATTAGAACACCACTCCAACAGTCAACACTAGGAAAGGCAATTATTCGAACACCTGTGATGG
TACAGCCAGGTGCTCCTCAGCAAGTGATGACTCAAATCATCAGGGGGCAGCCTGTCTCCACTGCAGTCTCCGCCCCTAACACGGTTTCCT
CAACACCTGGGCAGAAAAGCTTAACTTCAGCAACGTCCACTTCAAATATACAGTCTTCAGCCTCACAACCCCCTCGCCCCCAACAAGGAC
AAGTGAAGCTCACCATGGCTCAACTTACTCAGTTAACACAGGGCCACGGTGGCAATCAAGGTTTGACAGTAGTAATTCAAGGACAAGGTC
AAACTACTGGACAGTTGCAGTTGATACCTCAAGGGGTGACTGTACTCCCAGGCCCAGGCCAGCAGCTAATGCAAGCTGCAATGCCAAATG
GTACTGTTCAGCGATTCCTCTTTACCCCATTGGCAACAACAGCCACCACAGCCAGCACCACCACCACCACTGTTTCCACGACAGCAGCAG
GTACAGGTGAACAAAGGCAGAGTAAACTGTCACCCCAGATGCAGGTACATCAAGACAAAACCCTGCCACCAGCTCAGTCATCAAGTGTGG
GTCCAGCAGAAGCCCAGCCACAGACTGCTCAGCCTTCAGCTCAGCCCCAGCCCCAAACCCAGCCCCAGTCCCCAGCTCAGCCTGAAGTTC
AGACTCAGCCTGAAGTTCAGACCCAAACAACTGTTTCATCCCATGTCCCTTCTGAAGCACAACCCACCCACGCACAGTCATCCAAGCCCC
AAGTTGCAGCACAGTCTCAGCCTCAAAGTAATGTCCAAGGACAGTCTCCTGTTCGTGTCCAAAGTCCATCACAGACTCGAATACGTCCAT
CAACTCCATCCCAACTGTCTCCTGGACAACAATCCCAGGTTCAGACTACAACCTCACAACCGATTCCAATTCAACCACATACATCTCTTC
AGATACCTTCCCAAGGCCAGCCACAGTCACAACCCCAGGTACAGTCTTCAACTCAAACTCTTTCATCAGGACAAACTTTAAATCAAGTTA
CTGTTTCATCCCCATCCCGTCCTCAGCTACAAATACAGCAGCCACAGCCCCAAGTCATTGCTGTGCCTCAGCTGCAACAACAAGTCCAGG
TTCTCTCTCAGATCCAGTCACAGGTTGTGGCTCAGATACAGGCTCAGCAAAGTGGTGTGCCCCAGCAAATCAAACTCCAGTTACCTATCC
AAATTCAGCAAAGCAGTGCTGTGCAGACTCACCAGATTCAGAATGTGGTTACAGTGCAGGCAGCCAGTGTGCAAGAGCAGTTGCAAAGGG
TTCAGCAACTCAGGGATCAGCAGCAAAAGAAGAAACAGCAACAGATAGAAATTAAGCGTGAACACACCCTCCAAGCTTCTAATCAAAGTG
AAATCATTCAGAAACAGGTGGTGATGAAGCATAATGCTGTAATAGAACATTTAAAACAGAAAAAGAGCATGACTCCAGCTGAAAGAGAAG
AGAATCAAAGAATGATTGTCTGTAACCAGGTGATGAAGTATATTTTGGATAAGATAGATAAAGAAGAAAAACAGGCAGCAAAAAAACGGA
AGCGTGAAGAGAGTGTGGAGCAGAAACGTAGCAAGCAGAATGCCACTAAGCTGTCAGCTCTGCTCTTCAAGCACAAAGAGCAGCTCAGAG
CCGAGATCCTGAAGAAGAGAGCACTCCTGGACAAGGATCTGCAAATTGAAGTGCAGGAAGAGCTGAAGAGAGACCTGAAAATTAAGAAAG
AAAAAGACCTGATGCAGTTGGCTCAGGCCACAGCAGTAGCTGCACCCTGCCCCCCAGTGACACCAGCTCCTCCAGCCCCTCCAGCCCCTC
CACCTTCACCTCCCCCTCCACCTGCTGTGCAACACACAGGCCTTCTGTCCACGCCCACCTTACCTGCTGCTTCCCAGAAGAGGAAGCGGG
AAGAGGAAAAAGACTCCAGCTCAAAGTCCAAGAAAAAGAAAATGATCTCTACTACCTCAAAGGAAACTAAGAAGGACACAAAGCTTTACT
GTATCTGTAAAACGCCTTATGATGAATCTAAATTTTATATTGGCTGTGATCGGTGTCAGAATTGGTACCATGGGCGCTGCGTTGGCATCT
TGCAAAGTGAGGCAGAGCTCATTGATGAGTATGTCTGTCCACAGTGCCAGTCAACAGAGGATGCCATGACAGTGCTCACGCCACTAACAG
AGAAGGATTATGAGGGGTTGAAGAGGGTGCTCCGTTCCTTACAGGCCCATAAGATGGCCTGGCCTTTCCTTGAACCAGTAGACCCTAATG
ATGCACCAGATTATTATGGTGTTATTAAGGAACCTATGGACCTTGCCACCATGGAAGAAAGAGTACAAAGACGATATTATGAAAAGCTGA
CGGAATTTGTGGCAGATATGACCAAAATTTTTGATAACTGTCGTTACTACAATCCAAGTGACTCCCCATTTTACCAGTGTGCAGAAGTTC
TCGAATCATTCTTTGTACAGAAATTGAAAGGCTTCAAAGCTAGCAGGTCTCATAACAACAAACTGCAGTCTACAGCTTCTTAAAGTTCAG
CGTGTTAACCTAACATAAAACACAGCAAGAATCTGGTTGTCTGAACTATTTTAAATTAAGGAGCCAGATGTTTTTAGTCAGGCTATCCTG
ACAAGACTTGACCTAAACTTCGTTTTTATTGGTCATAACAGTCCAATTATATTCTTGGCCAATTTTGTCCAACGGACAAGAAAAAAGCAA
AGTCAACGACACCATTATCTTGTCAAGATCAGATGGTTTTACTATTGTGGCAGAAGCGAGAAAACTTTGTTTATTGAAAAAAAAAGAAAA
AGAAAGCAAGAAAAAAAGATACTATGGGGTCAAGTGTAACTCCATGGAAATGCCACGTCTGCTCTTCAGTGAAGAAGCTGGTTTAGAGTC
TCACAGAAAACTTTTGACTGTATTTATTTATTGTTGCAAAAAAGACGCTTTTTTATTGCTGCCCTCATTTGTCAGCTAATTATTTTTTCT
TATAAAATCCAGCCCCGGTTACATATAATCATCTGTATCTTATCATGATTCCTGTAGGTAAAAGTACAAGACGACCTCTAGATGTCTTTT
CTTTCTATGAAAGGAGCTGCTATGTACACATGTGCACACACACACAACTGGGAATCAACAATGAGTTTATTGTTCATGGTAGATTAAAAT
TAAGCTTGCATAAAGGTTGGGCTAAGTGGTCCTGGACTACAGACTCTGTTGCCTTGAATATAACAGTACAATTTGTCAATTACTCTGCAC
CAGGCTAAAATGAGTAAAATCTATTTGAAGGTATCTTGTTTGTAAACATTTGTCAGATTCTAATTTTTTTCTTTTGTATTAAAATTCAAC
TATGGATGTATATGAAACAAAATAAATGGAGATAATTTTTCTCCCACAGACAGAGGTGTCTTTGAATGTGCGCTAATGATTATCTGTAAG
CCTTTGTGGGGAGGGAGGCCTGCAAGGTCATGAAAGGCAGAAGAGTCTAATTGTGCCTGGATTTCTCCAGGACAGCAGTGGCCCCTCGTT
TTATCATTCCCAGTCCATTGTCATCACGTCAGAGAAAAATCTTCAGGGGTGCTAATCCTGTTGCATCAGTTGATCATACTAACGAGAACG
GTAATGCGACAAGATACACATTGCCTTCATCTGTACATTCTGTGATACCAGGCAAATTACCAATTACACACAGCTACTTATATTTTATGA
AGGGCATTTTTTAGATGACCTCATCCTCTGTGTTATTTGTTGATTGGGTTTGTTTTCTGTTTGTTGGTTTGTTTGTTTCTTCCACGTAAG
GAAAAGTAGTGTAAACAGTAGCGAGAAAATGGAAACCACAGAGGAAGATGTATTTTGCATGTTTTTCCTTTCAGTGTTCTTACACGTTGT
ATCACTGCATTGTGGTAATAGCTTCTATAAAATCTGCCATAGTTGGATTATGCAGCTTTGCAAAAATTTTTACTAGATTTTGCACTAACT
CATATTAGCTTTGTCCTACCAACTTCTGGAATTTATCTAATTATTGTTTTTCAAAGTTTCTTTCCTTTTAATGTTTCCCTGCTATGCAAA
ACCTTTCCCAGACCTCAGTTTCTTAAAAGAAAGATGTTGCTACAGTTCCCGATTCTTTCTTATTACAGGCTCAGGTGTACAGGTTATTCT
GGGTTAATTTTATCTAATGAAGCCCATTCCTTTTTGTACATAAAGATGTCACTTAAACTTATGCTTACAAACTAAAGACTAATCGCTCAA
TATGAAAACATGAAAAAATTTTTGCTTAAAGTATTAAGATGGAAGTAGTTAAATATGGGTTATTTTGTCCTTTTACTTTTTTAAAAAATG
TTACATATTGTATGCACTGTGCTGATGCAAGAATTCTACATTTTAATGAGTTATAAAATTATTCTGCATCTCATCACGTCACAGTATTTC
TGTACTATTTATTCATATATATAAATATATATGGGCTTAATCATTTAAAATTTGTTGCAGCAAGAACTTTCCTACCTGTAGGCAATAGAT
TGCTATGTTTTTAACAAATTGTGGCAAATTCTAAACAGCAATTCTTTTGTACGTAATAGGACATTTCATCCTAGAAAAATAAAGTAATGT

>64664_64664_6_PGS1-BPTF_PGS1_chr17_76400170_ENST00000262764_BPTF_chr17_65916131_ENST00000321892_length(amino acids)=1578AA_BP=467
MAVAAAAAAGPVFWRRLLGLLPGRPGLAALLGRLSDRLGRNRDRQRRRSPWLLLAPLLSPAVPQVTSPPCCLCPEGVHRFQWIRNLVPEF
GVSSSHVRVLSSPAEFFELMKGQIRVAKRRVVMASLYLGTGPLEQELVDCLESTLEKSLQAKFPSNLKVSILLDFTRGSRGRKNSRTMLL
PLLRRFPEQVRVSLFHTPHLRGLLRLLIPERFNETIGLQHIKVYLFDNSVILSGANLSDSYFTNRQDRYVFLQDCAEIADFFTELVDAVG
DVSLQLQGDDTVQVVDGMVHPYKGDRAEYCKAANKRVMDVINSARTRQQMLHAQTFHSNSLLTQEDAAAAGDRRPAPDTWIYPLIQMKPF
EIQIDEIVTETLLTEAERGAKVYLTTGYFNLTQAYMDLVLGTRAEYQILLASPEVNGFFGAKGVAGAIPAAYVHIERQFFSEVCSLGQQE
RVQLQEYWRRGWTFHAKETSETEITTTEIIKRRDVGPYGIRSEYCIRKIICPIGVPETPKETPTPQRKGLRSSALRPKRPETPKQTGPVI
IETWVAEEELELWEIRAFAERVEKEKAQAVEQQAKKRLEQQKPTVIATSTTSPTSSTTSTISPAQKVMVAPISGSVTTGTKMVLTTKVGS
PATVTFQQNKNFHQTFATWVKQGQSNSGVVQVQQKVLGIIPSSTGTSQQTFTSFQPRTATVTIRPNTSGSGGTTSNSQVITGPQIRPGMT
VIRTPLQQSTLGKAIIRTPVMVQPGAPQQVMTQIIRGQPVSTAVSAPNTVSSTPGQKSLTSATSTSNIQSSASQPPRPQQGQVKLTMAQL
TQLTQGHGGNQGLTVVIQGQGQTTGQLQLIPQGVTVLPGPGQQLMQAAMPNGTVQRFLFTPLATTATTASTTTTTVSTTAAGTGEQRQSK
LSPQMQVHQDKTLPPAQSSSVGPAEAQPQTAQPSAQPQPQTQPQSPAQPEVQTQPEVQTQTTVSSHVPSEAQPTHAQSSKPQVAAQSQPQ
SNVQGQSPVRVQSPSQTRIRPSTPSQLSPGQQSQVQTTTSQPIPIQPHTSLQIPSQGQPQSQPQVQSSTQTLSSGQTLNQVTVSSPSRPQ
LQIQQPQPQVIAVPQLQQQVQVLSQIQSQVVAQIQAQQSGVPQQIKLQLPIQIQQSSAVQTHQIQNVVTVQAASVQEQLQRVQQLRDQQQ
KKKQQQIEIKREHTLQASNQSEIIQKQVVMKHNAVIEHLKQKKSMTPAEREENQRMIVCNQVMKYILDKIDKEEKQAAKKRKREESVEQK
RSKQNATKLSALLFKHKEQLRAEILKKRALLDKDLQIEVQEELKRDLKIKKEKDLMQLAQATAVAAPCPPVTPAPPAPPAPPPSPPPPPA
VQHTGLLSTPTLPAASQKRKREEEKDSSSKSKKKKMISTTSKETKKDTKLYCICKTPYDESKFYIGCDRCQNWYHGRCVGILQSEAELID
EYVCPQCQSTEDAMTVLTPLTEKDYEGLKRVLRSLQAHKMAWPFLEPVDPNDAPDYYGVIKEPMDLATMEERVQRRYYEKLTEFVADMTK

--------------------------------------------------------------
>64664_64664_7_PGS1-BPTF_PGS1_chr17_76400170_ENST00000262764_BPTF_chr17_65916131_ENST00000335221_length(transcript)=6424nt_BP=1428nt
AGCGGAAGCGGAAGCGGCGAGTCTCCATGGCGGTGGCGGCGGCAGCTGCGGCGGGACCCGTGTTCTGGAGGCGACTGCTGGGCCTCCTGC
CTGGCCGCCCAGGGCTGGCCGCGCTCCTGGGACGCCTGTCCGACCGCCTCGGCAGGAACCGGGACCGCCAGCGCAGGAGGTCACCATGGC
TGTTATTGGCTCCCTTGCTGTCCCCAGCTGTTCCCCAGGTCACCTCCCCACCTTGCTGCCTGTGTCCAGAAGGCGTGCACCGGTTCCAGT
GGATCAGAAACCTGGTTCCAGAATTTGGAGTCTCCAGTTCTCACGTTAGGGTGCTTTCTTCCCCGGCAGAGTTTTTCGAGCTCATGAAGG
GGCAGATAAGAGTAGCCAAGAGGCGGGTCGTGATGGCATCCCTCTACCTGGGGACAGGTCCTTTGGAACAGGAGCTGGTGGACTGCCTGG
AAAGTACTCTAGAAAAGTCACTCCAAGCAAAGTTTCCTTCAAATCTCAAGGTCTCCATTCTCTTAGACTTCACGCGGGGCTCACGAGGCC
GGAAGAACTCCCGCACAATGCTGCTCCCACTCCTGCGGAGGTTCCCAGAGCAGGTCCGAGTCTCCCTCTTTCACACGCCGCACCTCCGTG
GGCTGCTTCGGCTCCTCATCCCTGAGCGCTTCAACGAGACCATCGGCCTCCAGCACATTAAGGTGTACCTCTTCGACAACAGCGTCATCT
TGAGCGGTGCAAACCTGAGTGACTCCTACTTCACCAACCGCCAGGACCGCTACGTGTTCCTGCAGGACTGTGCGGAGATTGCCGACTTCT
TCACGGAGCTGGTGGACGCGGTGGGGGATGTGTCCCTGCAGCTGCAGGGGGACGACACGGTGCAGGTGGTGGATGGGATGGTGCATCCTT
ACAAAGGGGACCGGGCCGAGTACTGCAAGGCAGCCAATAAGAGGGTCATGGATGTGATCAACTCAGCCAGGACCCGCCAGCAGATGCTGC
ATGCCCAGACCTTCCACAGCAACTCTCTTTTGACCCAGGAAGATGCAGCAGCTGCTGGGGATCGCAGACCAGCCCCTGACACCTGGATTT
ATCCGCTGATTCAGATGAAGCCCTTCGAGATTCAAATCGATGAGATTGTCACTGAGACCCTGTTGACTGAGGCGGAGCGCGGGGCAAAGG
TCTACCTCACCACTGGCTATTTCAACCTGACCCAGGCCTACATGGACCTGGTCTTGGGCACTCGGGCTGAGTACCAGATCCTGCTGGCCT
CACCAGAGGTGAATGGCTTCTTTGGGGCCAAGGGGGTGGCCGGCGCCATCCCAGCGGCCTATGTGCACATCGAGCGACAGTTCTTCAGTG
AGGTGTGCAGCCTGGGACAGCAGGAGCGGGTCCAGCTTCAGGAGTACTGGCGGAGGGGCTGGACGTTCCACGCCAAAGAAACATCCGAAA
CTGAAATCACAACAACAGAAATAATTAAGAGGAGAGATGTTGGTCCTTATGGCATTCGATCTGAATATTGTATCAGGAAAATCATTTGTC
CCATTGGAGTTCCAGAAACACCAAAAGAAACGCCTACACCTCAGAGGAAAGGCCTTCGATCAAGTGCACTGCGGCCAAAGAGACCAGAAA
CGCCCAAGCAAACTGGCCCTGTTATTATTGAAACCTGGGTAGCAGAAGAAGAACTGGAATTGTGGGAGATCAGGGCATTTGCTGAGAGAG
TGGAGAAAGAAAAGGCACAAGCAGTTGAGCAACAGGCTAAGAAACGACTGGAGCAGCAGAAGCCGACAGTGATTGCAACTTCCACTACTT
CCCCAACAAGCAGTACAACCAGCACCATCTCTCCAGCACAGAAGGTTATGGTGGCCCCCATAAGTGGCTCAGTTACAACTGGAACCAAAA
TGGTACTAACTACTAAAGTTGGATCTCCAGCTACAGTAACATTCCAACAAAACAAGAACTTTCATCAAACCTTTGCTACATGGGTTAAGC
AAGGCCAGTCAAATTCAGGCGTTGTTCAAGTACAGCAGAAAGTCCTGGGTATCATTCCATCAAGTACAGGTACCAGTCAGCAAACCTTTA
CTTCATTCCAGCCCAGGACAGCAACAGTCACAATTAGGCCCAATACCTCAGGCTCTGGAGGAACCACAAGCAATTCACAAGTAATCACAG
GGCCTCAGATTCGCCCTGGTATGACCGTGATTAGAACACCACTCCAACAGTCAACACTAGGAAAGGCAATTATTCGAACACCTGTGATGG
TACAGCCAGGTGCTCCTCAGCAAGTGATGACTCAAATCATCAGGGGGCAGCCTGTCTCCACTGCAGTCTCCGCCCCTAACACGGTTTCCT
CAACACCTGGGCAGAAAAGCTTAACTTCAGCAACGTCCACTTCAAATATACAGTCTTCAGCCTCACAACCCCCTCGCCCCCAACAAGGAC
AAGTGAAGCTCACCATGGCTCAACTTACTCAGTTAACACAGGGCCACGGTGGCAATCAAGGTTTGACAGTAGTAATTCAAGGACAAGGTC
AAACTACTGGACAGTTGCAGTTGATACCTCAAGGGGTGACTGTACTCCCAGGCCCAGGCCAGCAGCTAATGCAAGCTGCAATGCCAAATG
GTACTGTTCAGCGATTCCTCTTTACCCCATTGGCAACAACAGCCACCACAGCCAGCACCACCACCACCACTGTTTCCACGACAGCAGCAG
GTACAGGTGAACAAAGGCAGAGTAAACTGTCACCCCAGATGCAGGTACATCAAGACAAAACCCTGCCACCAGCTCAGTCATCAAGTGTGG
GTCCAGCAGAAGCCCAGCCACAGACTGCTCAGCCTTCAGCTCAGCCCCAGCCCCAAACCCAGCCCCAGTCCCCAGCTCAGCCTGAAGTTC
AGACTCAGCCTGAAGTTCAGACCCAAACAACTGTTTCATCCCATGTCCCTTCTGAAGCACAACCCACCCACGCACAGTCATCCAAGCCCC
AAGTTGCAGCACAGTCTCAGCCTCAAAGTAATGTCCAAGGACAGTCTCCTGTTCGTGTCCAAAGTCCATCACAGACTCGAATACGTCCAT
CAACTCCATCCCAACTGTCTCCTGGACAACAATCCCAGGTTCAGACTACAACCTCACAACCGATTCCAATTCAACCACATACATCTCTTC
AGATACCTTCCCAAGGCCAGCCACAGTCACAACCCCAGGTGGTGATGAAGCATAATGCTGTAATAGAACATTTAAAACAGAAAAAGAGCA
TGACTCCAGCTGAAAGAGAAGAGAATCAAAGAATGATTGTCTGTAACCAGGTGATGAAGTATATTTTGGATAAGATAGATAAAGAAGAAA
AACAGGCAGCAAAAAAACGGAAGCGTGAAGAGAGTGTGGAGCAGAAACGTAGCAAGCAGAATGCCACTAAGCTGTCAGCTCTGCTCTTCA
AGCACAAAGAGCAGCTCAGAGCCGAGATCCTGAAGAAGAGAGCACTCCTGGACAAGGATCTGCAAATTGAAGTGCAGGAAGAGCTGAAGA
GAGACCTGAAAATTAAGAAAGAAAAAGACCTGATGCAGTTGGCTCAGGCCACAGCAGTAGCTGCACCCTGCCCCCCAGTGACACCAGCTC
CTCCAGCCCCTCCAGCCCCTCCACCTTCACCTCCCCCTCCACCTGCTGTGCAACACACAGGCCTTCTGTCCACGCCCACCTTACCTGCTG
CTTCCCAGAAGAGGAAGCGGGAAGAGGAAAAAGACTCCAGCTCAAAGTCCAAGAAAAAGAAAATGATCTCTACTACCTCAAAGGAAACTA
AGAAGGACACAAAGCTTTACTGTATCTGTAAAACGCCTTATGATGAATCTAAATTTTATATTGGCTGTGATCGGTGTCAGAATTGGTACC
ATGGGCGCTGCGTTGGCATCTTGCAAAGTGAGGCAGAGCTCATTGATGAGTATGTCTGTCCACAGTGCCAGTCAACAGAGGATGCCATGA
CAGTGCTCACGCCACTAACAGAGAAGGATTATGAGGGGTTGAAGAGGGTGCTCCGTTCCTTACAGGCCCATAAGATGGCCTGGCCTTTCC
TTGAACCAGTAGACCCTAATGATGCACCAGATTATTATGGTGTTATTAAGGAACCTATGGACCTTGCCACCATGGAAGAAAGAGTACAAA
GACGATATTATGAAAAGCTGACGGAATTTGTGGCAGATATGACCAAAATTTTTGATAACTGTCGTTACTACAATCCAAGTGACTCCCCAT
TTTACCAGTGTGCAGAAGTTCTCGAATCATTCTTTGTACAGAAATTGAAAGGCTTCAAAGCTAGCAGGTCTCATAACAACAAACTGCAGT
CTACAGCTTCTTAAAGTTCAGCGTGTTAACCTAACATAAAACACAGCAAGAATCTGGTTGTCTGAACTATTTTAAATTAAGGAGCCAGAT
GTTTTTAGTCAGGCTATCCTGACAAGACTTGACCTAAACTTCGTTTTTATTGGTCATAACAGTCCAATTATATTCTTGGCCAATTTTGTC
CAACGGACAAGAAAAAAGCAAAGTCAACGACACCATTATCTTGTCAAGATCAGATGGTTTTACTATTGTGGCAGAAGCGAGAAAACTTTG
TTTATTGAAAAAAAAAGAAAAAGAAAGCAAGAAAAAAAGATACTATGGGGTCAAGTGTAACTCCATGGAAATGCCACGTCTGCTCTTCAG
TGAAGAAGCTGGTTTAGAGTCTCACAGAAAACTTTTGACTGTATTTATTTATTGTTGCAAAAAAGACGCTTTTTTATTGCTGCCCTCATT
TGTCAGCTAATTATTTTTTCTTATAAAATCCAGCCCCGGTTACATATAATCATCTGTATCTTATCATGATTCCTGTAGGTAAAAGTACAA
GACGACCTCTAGATGTCTTTTCTTTCTATGAAAGGAGCTGCTATGTACACATGTGCACACACACACAACTGGGAATCAACAATGAGTTTA
TTGTTCATGGTAGATTAAAATTAAGCTTGCATAAAGGTTGGGCTAAGTGGTCCTGGACTACAGACTCTGTTGCCTTGAATATAACAGTAC
AATTTGTCAATTACTCTGCACCAGGCTAAAATGAGTAAAATCTATTTGAAGGTATCTTGTTTGTAAACATTTGTCAGATTCTAATTTTTT
TCTTTTGTATTAAAATTCAACTATGGATGTATATGAAACAAAATAAATGGAGATAATTTTTCTCCCACAGACAGAGGTGTCTTTGAATGT
GCGCTAATGATTATCTGTAAGCCTTTGTGGGGAGGGAGGCCTGCAAGGTCATGAAAGGCAGAAGAGTCTAATTGTGCCTGGATTTCTCCA
GGACAGCAGTGGCCCCTCGTTTTATCATTCCCAGTCCATTGTCATCACGTCAGAGAAAAATCTTCAGGGGTGCTAATCCTGTTGCATCAG
TTGATCATACTAACGAGAACGGTAATGCGACAAGATACACATTGCCTTCATCTGTACATTCTGTGATACCAGGCAAATTACCAATTACAC
ACAGCTACTTATATTTTATGAAGGGCATTTTTTAGATGACCTCATCCTCTGTGTTATTTGTTGATTGGGTTTGTTTTCTGTTTGTTGGTT
TGTTTGTTTCTTCCACGTAAGGAAAAGTAGTGTAAACAGTAGCGAGAAAATGGAAACCACAGAGGAAGATGTATTTTGCATGTTTTTCCT
TTCAGTGTTCTTACACGTTGTATCACTGCATTGTGGTAATAGCTTCTATAAAATCTGCCATAGTTGGATTATGCAGCTTTGCAAAAATTT
TTACTAGATTTTGCACTAACTCATATTAGCTTTGTCCTACCAACTTCTGGAATTTATCTAATTATTGTTTTTCAAAGTTTCTTTCCTTTT
AATGTTTCCCTGCTATGCAAAACCTTTCCCAGACCTCAGTTTCTTAAAAGAAAGATGTTGCTACAGTTCCCGATTCTTTCTTATTACAGG
CTCAGGTGTACAGGTTATTCTGGGTTAATTTTATCTAATGAAGCCCATTCCTTTTTGTACATAAAGATGTCACTTAAACTTATGCTTACA
AACTAAAGACTAATCGCTCAATATGAAAACATGAAAAAATTTTTGCTTAAAGTATTAAGATGGAAGTAGTTAAATATGGGTTATTTTGTC
CTTTTACTTTTTTAAAAAATGTTACATATTGTATGCACTGTGCTGATGCAAGAATTCTACATTTTAATGAGTTATAAAATTATTCTGCAT
CTCATCACGTCACAGTATTTCTGTACTATTTATTCATATATATAAATATATATGGGCTTAATCATTTAAAATTTGTTGCAGCAAGAACTT
TCCTACCTGTAGGCAATAGATTGCTATGTTTTTAACAAATTGTGGCAAATTCTAAACAGCAATTCTTTTGTACGTAATAGGACATTTCAT

>64664_64664_7_PGS1-BPTF_PGS1_chr17_76400170_ENST00000262764_BPTF_chr17_65916131_ENST00000335221_length(amino acids)=1435AA_BP=467
MAVAAAAAAGPVFWRRLLGLLPGRPGLAALLGRLSDRLGRNRDRQRRRSPWLLLAPLLSPAVPQVTSPPCCLCPEGVHRFQWIRNLVPEF
GVSSSHVRVLSSPAEFFELMKGQIRVAKRRVVMASLYLGTGPLEQELVDCLESTLEKSLQAKFPSNLKVSILLDFTRGSRGRKNSRTMLL
PLLRRFPEQVRVSLFHTPHLRGLLRLLIPERFNETIGLQHIKVYLFDNSVILSGANLSDSYFTNRQDRYVFLQDCAEIADFFTELVDAVG
DVSLQLQGDDTVQVVDGMVHPYKGDRAEYCKAANKRVMDVINSARTRQQMLHAQTFHSNSLLTQEDAAAAGDRRPAPDTWIYPLIQMKPF
EIQIDEIVTETLLTEAERGAKVYLTTGYFNLTQAYMDLVLGTRAEYQILLASPEVNGFFGAKGVAGAIPAAYVHIERQFFSEVCSLGQQE
RVQLQEYWRRGWTFHAKETSETEITTTEIIKRRDVGPYGIRSEYCIRKIICPIGVPETPKETPTPQRKGLRSSALRPKRPETPKQTGPVI
IETWVAEEELELWEIRAFAERVEKEKAQAVEQQAKKRLEQQKPTVIATSTTSPTSSTTSTISPAQKVMVAPISGSVTTGTKMVLTTKVGS
PATVTFQQNKNFHQTFATWVKQGQSNSGVVQVQQKVLGIIPSSTGTSQQTFTSFQPRTATVTIRPNTSGSGGTTSNSQVITGPQIRPGMT
VIRTPLQQSTLGKAIIRTPVMVQPGAPQQVMTQIIRGQPVSTAVSAPNTVSSTPGQKSLTSATSTSNIQSSASQPPRPQQGQVKLTMAQL
TQLTQGHGGNQGLTVVIQGQGQTTGQLQLIPQGVTVLPGPGQQLMQAAMPNGTVQRFLFTPLATTATTASTTTTTVSTTAAGTGEQRQSK
LSPQMQVHQDKTLPPAQSSSVGPAEAQPQTAQPSAQPQPQTQPQSPAQPEVQTQPEVQTQTTVSSHVPSEAQPTHAQSSKPQVAAQSQPQ
SNVQGQSPVRVQSPSQTRIRPSTPSQLSPGQQSQVQTTTSQPIPIQPHTSLQIPSQGQPQSQPQVVMKHNAVIEHLKQKKSMTPAEREEN
QRMIVCNQVMKYILDKIDKEEKQAAKKRKREESVEQKRSKQNATKLSALLFKHKEQLRAEILKKRALLDKDLQIEVQEELKRDLKIKKEK
DLMQLAQATAVAAPCPPVTPAPPAPPAPPPSPPPPPAVQHTGLLSTPTLPAASQKRKREEEKDSSSKSKKKKMISTTSKETKKDTKLYCI
CKTPYDESKFYIGCDRCQNWYHGRCVGILQSEAELIDEYVCPQCQSTEDAMTVLTPLTEKDYEGLKRVLRSLQAHKMAWPFLEPVDPNDA

--------------------------------------------------------------
>64664_64664_8_PGS1-BPTF_PGS1_chr17_76400170_ENST00000262764_BPTF_chr17_65916131_ENST00000424123_length(transcript)=4334nt_BP=1428nt
AGCGGAAGCGGAAGCGGCGAGTCTCCATGGCGGTGGCGGCGGCAGCTGCGGCGGGACCCGTGTTCTGGAGGCGACTGCTGGGCCTCCTGC
CTGGCCGCCCAGGGCTGGCCGCGCTCCTGGGACGCCTGTCCGACCGCCTCGGCAGGAACCGGGACCGCCAGCGCAGGAGGTCACCATGGC
TGTTATTGGCTCCCTTGCTGTCCCCAGCTGTTCCCCAGGTCACCTCCCCACCTTGCTGCCTGTGTCCAGAAGGCGTGCACCGGTTCCAGT
GGATCAGAAACCTGGTTCCAGAATTTGGAGTCTCCAGTTCTCACGTTAGGGTGCTTTCTTCCCCGGCAGAGTTTTTCGAGCTCATGAAGG
GGCAGATAAGAGTAGCCAAGAGGCGGGTCGTGATGGCATCCCTCTACCTGGGGACAGGTCCTTTGGAACAGGAGCTGGTGGACTGCCTGG
AAAGTACTCTAGAAAAGTCACTCCAAGCAAAGTTTCCTTCAAATCTCAAGGTCTCCATTCTCTTAGACTTCACGCGGGGCTCACGAGGCC
GGAAGAACTCCCGCACAATGCTGCTCCCACTCCTGCGGAGGTTCCCAGAGCAGGTCCGAGTCTCCCTCTTTCACACGCCGCACCTCCGTG
GGCTGCTTCGGCTCCTCATCCCTGAGCGCTTCAACGAGACCATCGGCCTCCAGCACATTAAGGTGTACCTCTTCGACAACAGCGTCATCT
TGAGCGGTGCAAACCTGAGTGACTCCTACTTCACCAACCGCCAGGACCGCTACGTGTTCCTGCAGGACTGTGCGGAGATTGCCGACTTCT
TCACGGAGCTGGTGGACGCGGTGGGGGATGTGTCCCTGCAGCTGCAGGGGGACGACACGGTGCAGGTGGTGGATGGGATGGTGCATCCTT
ACAAAGGGGACCGGGCCGAGTACTGCAAGGCAGCCAATAAGAGGGTCATGGATGTGATCAACTCAGCCAGGACCCGCCAGCAGATGCTGC
ATGCCCAGACCTTCCACAGCAACTCTCTTTTGACCCAGGAAGATGCAGCAGCTGCTGGGGATCGCAGACCAGCCCCTGACACCTGGATTT
ATCCGCTGATTCAGATGAAGCCCTTCGAGATTCAAATCGATGAGATTGTCACTGAGACCCTGTTGACTGAGGCGGAGCGCGGGGCAAAGG
TCTACCTCACCACTGGCTATTTCAACCTGACCCAGGCCTACATGGACCTGGTCTTGGGCACTCGGGCTGAGTACCAGATCCTGCTGGCCT
CACCAGAGGTGAATGGCTTCTTTGGGGCCAAGGGGGTGGCCGGCGCCATCCCAGCGGCCTATGTGCACATCGAGCGACAGTTCTTCAGTG
AGGTGTGCAGCCTGGGACAGCAGGAGCGGGTCCAGCTTCAGGAGTACTGGCGGAGGGGCTGGACGTTCCACGCCAAAGAAACATCCGAAA
CTGAAATCACAACAACAGAAATAATTAAGAGGAGAGATGTTGGTCCTTATGGCATTCGATCTGAATATTGTATCAGGAAAATCATTTGTC
CCATTGGAGTTCCAGAAACACCAAAAGAAACGCCTACACCTCAGAGGAAAGGCCTTCGATCAAGTGCACTGCGGCCAAAGAGACCAGAAA
CGCCCAAGCAAACTGGCCCTGTTATTATTGAAACCTGGGTAGCAGAAGAAGAACTGGAATTGTGGGAGATCAGGGCATTTGCTGAGAGAG
TGGAGAAAGAAAAGGCACAAGCAGTTGAGCAACAGGCTAAGAAACGACTGGAGCAGCAGAAGCCGACAGTGATTGCAACTTCCACTACTT
CCCCAACAAGCAGTACAACCAGCACCATCTCTCCAGCACAGAAGGTTATGGTGGCCCCCATAAGTGGCTCAGTTACAACTGGAACCAAAA
TGGTACTAACTACTAAAGTTGGATCTCCAGCTACAGTAACATTCCAACAAAACAAGAACTTTCATCAAACCTTTGCTACATGGGTTAAGC
AAGGCCAGTCAAATTCAGGCGTTGTTCAAGTACAGCAGAAAGTCCTGGGTATCATTCCATCAAGTACAGGTACCAGTCAGCAAACCTTTA
CTTCATTCCAGCCCAGGACAGCAACAGTCACAATTAGGCCCAATACCTCAGGCTCTGGAGGAACCACAAGCAATTCACAAGTAATCACAG
GGCCTCAGATTCGCCCTGGTATGACCGTGATTAGAACACCACTCCAACAGTCAACACTAGGAAAGGCAATTATTCGAACACCTGTGATGG
TACAGCCAGGTGCTCCTCAGCAAGTGATGACTCAAATCATCAGGGGGCAGCCTGTCTCCACTGCAGTCTCCGCCCCTAACACGGTTTCCT
CAACACCTGGGCAGAAAAGCTTAACTTCAGCAACGTCCACTTCAAATATACAGTCTTCAGCCTCACAACCCCCTCGCCCCCAACAAGGAC
AAGTGAAGCTCACCATGGCTCAACTTACTCAGTTAACACAGGGCCACGGTGGCAATCAAGGTTTGACAGTAGTAATTCAAGGACAAGGTC
AAACTACTGGACAGTTGCAGTTGATACCTCAAGGGGTGACTGTACTCCCAGGCCCAGGCCAGCAGCTAATGCAAGCTGCAATGCCAAATG
GTACTGTTCAGCGATTCCTCTTTACCCCATTGGCAACAACAGCCACCACAGCCAGCACCACCACCACCACTGTTTCCACGACAGCAGCAG
GTACAGGTGAACAAAGGCAGAGTAAACTGTCACCCCAGATGCAGGTACATCAAGACAAAACCCTGCCACCAGCTCAGTCATCAAGTGTGG
GTCCAGCAGAAGCCCAGCCACAGACTGCTCAGCCTTCAGCTCAGCCCCAGCCCCAAACCCAGCCCCAGTCCCCAGCTCAGCCTGAAGTTC
AGACTCAGCCTGAAGTTCAGACCCAAACAACTGTTTCATCCCATGTCCCTTCTGAAGCACAACCCACCCACGCACAGTCATCCAAGCCCC
AAGTTGCAGCACAGTCTCAGCCTCAAAGTAATGTCCAAGGACAGTCTCCTGTTCGTGTCCAAAGTCCATCACAGACTCGAATACGTCCAT
CAACTCCATCCCAACTGTCTCCTGGACAACAATCCCAGGTTCAGACTACAACCTCACAACCGATTCCAATTCAACCACATACATCTCTTC
AGATACCTTCCCAAGGCCAGCCACAGTCACAACCCCAGGTGGTGATGAAGCATAATGCTGTAATAGAACATTTAAAACAGAAAAAGAGCA
TGACTCCAGCTGAAAGAGAAGAGAATCAAAGAATGATTGTCTGTAACCAGGTGATGAAGTATATTTTGGATAAGATAGATAAAGAAGAAA
AACAGGCAGCAAAAAAACGGAAGCGTGAAGAGAGTGTGGAGCAGAAACGTAGCAAGCAGAATGCCACTAAGCTGTCAGCTCTGCTCTTCA
AGCACAAAGAGCAGCTCAGAGCCGAGATCCTGAAGAAGAGAGCACTCCTGGACAAGGATCTGCAAATTGAAGTGCAGGAAGAGCTGAAGA
GAGACCTGAAAATTAAGAAAGAAAAAGACCTGATGCAGTTGGCTCAGGCCACAGCAGTAGCTGCACCCTGCCCCCCAGTGACACCAGCTC
CTCCAGCCCCTCCAGCCCCTCCACCTTCACCTCCCCCTCCACCTGCTGTGCAACACACAGGCCTTCTGTCCACGCCCACCTTACCTGCTG
CTTCCCAGAAGAGGAAGCGGGAAGAGGAAAAAGACTCCAGCTCAAAGTCCAAGAAAAAGAAAATGATCTCTACTACCTCAAAGGAAACTA
AGAAGGACACAAAGCTTTACTGTATCTGTAAAACGCCTTATGATGAATCTAAATTTTATATTGGCTGTGATCGGTGTCAGAATTGGTACC
ATGGGCGCTGCGTTGGCATCTTGCAAAGTGAGGCAGAGCTCATTGATGAGTATGTCTGTCCACAGTGCCAGTCAACAGAGGATGCCATGA
CAGTGCTCACGCCACTAACAGAGAAGGATTATGAGGGGTTGAAGAGGGTGCTCCGTTCCTTACAGGCCCATAAGATGGCCTGGCCTTTCC
TTGAACCAGTAGACCCTAATGATGCACCAGATTATTATGGTGTTATTAAGGAACCTATGGACCTTGCCACCATGGAAGAAAGAGTACAAA
GACGATATTATGAAAAGCTGACGGAATTTGTGGCAGATATGACCAAAATTTTTGATAACTGTCGTTACTACAATCCAAGTGACTCCCCAT
TTTACCAGTGTGCAGAAGTTCTCGAATCATTCTTTGTACAGAAATTGAAAGGCTTCAAAGCTAGCAGGTCTCATAACAACAAACTGCAGT

>64664_64664_8_PGS1-BPTF_PGS1_chr17_76400170_ENST00000262764_BPTF_chr17_65916131_ENST00000424123_length(amino acids)=1436AA_BP=467
MAVAAAAAAGPVFWRRLLGLLPGRPGLAALLGRLSDRLGRNRDRQRRRSPWLLLAPLLSPAVPQVTSPPCCLCPEGVHRFQWIRNLVPEF
GVSSSHVRVLSSPAEFFELMKGQIRVAKRRVVMASLYLGTGPLEQELVDCLESTLEKSLQAKFPSNLKVSILLDFTRGSRGRKNSRTMLL
PLLRRFPEQVRVSLFHTPHLRGLLRLLIPERFNETIGLQHIKVYLFDNSVILSGANLSDSYFTNRQDRYVFLQDCAEIADFFTELVDAVG
DVSLQLQGDDTVQVVDGMVHPYKGDRAEYCKAANKRVMDVINSARTRQQMLHAQTFHSNSLLTQEDAAAAGDRRPAPDTWIYPLIQMKPF
EIQIDEIVTETLLTEAERGAKVYLTTGYFNLTQAYMDLVLGTRAEYQILLASPEVNGFFGAKGVAGAIPAAYVHIERQFFSEVCSLGQQE
RVQLQEYWRRGWTFHAKETSETEITTTEIIKRRDVGPYGIRSEYCIRKIICPIGVPETPKETPTPQRKGLRSSALRPKRPETPKQTGPVI
IETWVAEEELELWEIRAFAERVEKEKAQAVEQQAKKRLEQQKPTVIATSTTSPTSSTTSTISPAQKVMVAPISGSVTTGTKMVLTTKVGS
PATVTFQQNKNFHQTFATWVKQGQSNSGVVQVQQKVLGIIPSSTGTSQQTFTSFQPRTATVTIRPNTSGSGGTTSNSQVITGPQIRPGMT
VIRTPLQQSTLGKAIIRTPVMVQPGAPQQVMTQIIRGQPVSTAVSAPNTVSSTPGQKSLTSATSTSNIQSSASQPPRPQQGQVKLTMAQL
TQLTQGHGGNQGLTVVIQGQGQTTGQLQLIPQGVTVLPGPGQQLMQAAMPNGTVQRFLFTPLATTATTASTTTTTVSTTAAGTGEQRQSK
LSPQMQVHQDKTLPPAQSSSVGPAEAQPQTAQPSAQPQPQTQPQSPAQPEVQTQPEVQTQTTVSSHVPSEAQPTHAQSSKPQVAAQSQPQ
SNVQGQSPVRVQSPSQTRIRPSTPSQLSPGQQSQVQTTTSQPIPIQPHTSLQIPSQGQPQSQPQVVMKHNAVIEHLKQKKSMTPAEREEN
QRMIVCNQVMKYILDKIDKEEKQAAKKRKREESVEQKRSKQNATKLSALLFKHKEQLRAEILKKRALLDKDLQIEVQEELKRDLKIKKEK
DLMQLAQATAVAAPCPPVTPAPPAPPAPPPSPPPPPAVQHTGLLSTPTLPAASQKRKREEEKDSSSKSKKKKMISTTSKETKKDTKLYCI
CKTPYDESKFYIGCDRCQNWYHGRCVGILQSEAELIDEYVCPQCQSTEDAMTVLTPLTEKDYEGLKRVLRSLQAHKMAWPFLEPVDPNDA

--------------------------------------------------------------
>64664_64664_9_PGS1-BPTF_PGS1_chr17_76400170_ENST00000329897_BPTF_chr17_65916130_ENST00000306378_length(transcript)=5490nt_BP=1290nt
CTCCATGGCGGTGGCGGCGGCAGCTGCGGCGGGACCCGTGTTCTGGAGGCGACTGCTGGGCCTCCTGCCTGGCCGCCCAGGGCTGGCCGC
GCTCCTGGGACGCCTGTCCGACCGCCTCGGCAGGAACCGGGACCGCCAGCGCAGGAGCTGTTCCCCAGGTCACCTCCCCACCTTGCTGCC
TGTGTCCAGAAGGCGTGCACCGGTTCCAGTGGATCAGAAACCTGGTTCCAGAATTTGGAGTCTCCAGTTCTCACGTTAGGGTGCTTTCTT
CCCCGGCAGAGTTTTTCGAGCTCATGAAGGTGGACTGCCTGGAAAGTACTCTAGAAAAGTCACTCCAAGCAAAGTTTCCTTCAAATCTCA
AGGTCTCCATTCTCTTAGACTTCACGCGGGGCTCACGAGGCCGGAAGAACTCCCGCACAATGCTGCTCCCACTCCTGCGGAGGTTCCCAG
AGCAGGTCCGAGTCTCCCTCTTTCACACGCCGCACCTCCGTGGGCTGCTTCGGCTCCTCATCCCTGAGCGCTTCAACGAGACCATCGGCC
TCCAGCACATTAAGGTGTACCTCTTCGACAACAGCGTCATCTTGAGCGGTGCAAACCTGAGTGACTCCTACTTCACCAACCGCCAGGACC
GCTACGTGTTCCTGCAGGACTGTGCGGAGATTGCCGACTTCTTCACGGAGCTGGTGGACGCGGTGGGGGATGTGTCCCTGCAGCTGCAGG
GGGACGACACGGTGCAGGTGGTGGATGGGATGGTGCATCCTTACAAAGGGGACCGGGCCGAGTACTGCAAGGCAGCCAATAAGAGGGTCA
TGGATGTGATCAACTCAGCCAGGACCCGCCAGCAGATGCTGCATGCCCAGACCTTCCACAGCAACTCTCTTTTGACCCAGGAAGATGCAG
CAGCTGCTGGGGATCGCAGACCAGCCCCTGACACCTGGATTTATCCGCTGATTCAGATGAAGCCCTTCGAGATTCAAATCGATGAGATTG
TCACTGAGACCCTGTTGACTGAGGCGGAGCGCGGGGCAAAGGTCTACCTCACCACTGGCTATTTCAACCTGACCCAGGCCTACATGGACC
TGGTCTTGGGCACTCGGGCTGAGTACCAGATCCTGCTGGCCTCACCAGAGGTGAATGGCTTCTTTGGGGCCAAGGGGGTGGCCGGCGCCA
TCCCAGCGGCCTATGTGCACATCGAGCGACAGTTCTTCAGTGAGGTGTGCAGCCTGGGACAGCAGGAGCGGGTCCAGCTTCAGGAGTACT
GGCGGAGGGGCTGGACGTTCCACGCCAAAGAAACATCCGAAACTGAAATCACAACAACAGAAATAATTAAGAGGAGAGATGTTGGTCCTT
ATGGCATTCGATCTGAATATTGTATCAGGAAAATCATTTGTCCCATTGGAGTTCCAGAAACACCAAAAGAAACGCCTACACCTCAGAGGA
AAGGCCTTCGATCAAGTGCACTGCGGCCAAAGAGACCAGAAACGCCCAAGCAAACTGGCCCTGTTATTATTGAAACCTGGGTAGCAGAAG
AAGAACTGGAATTGTGGGAGATCAGGGCATTTGCTGAGAGAGTGGAGAAAGAAAAGGCACAAGCAGTTGAGCAACAGGCTAAGAAACGAC
TGGAGCAGCAGAAGCCGACAGTGATTGCAACTTCCACTACTTCCCCAACAAGCAGTACAACCAGCACCATCTCTCCAGCACAGAAGGTTA
TGGTGGCCCCCATAAGTGGCTCAGTTACAACTGGAACCAAAATGGTACTAACTACTAAAGTTGGATCTCCAGCTACAGTAACATTCCAAC
AAAACAAGAACTTTCATCAAACCTTTGCTACATGGGTTAAGCAAGGCCAGTCAAATTCAGGCGTTGTTCAAGTACAGCAGAAAGTCCTGG
GTATCATTCCATCAAGTACAGGTACCAGTCAGCAAACCTTTACTTCATTCCAGCCCAGGACAGCAACAGTCACAATTAGGCCCAATACCT
CAGGCTCTGGAGGAACCACAAGCAATTCACAAGTAATCACAGGGCCTCAGATTCGCCCTGGTATGACCGTGATTAGAACACCACTCCAAC
AGTCAACACTAGGAAAGGCAATTATTCGAACACCTGTGATGGTACAGCCAGGTGCTCCTCAGCAAGTGATGACTCAAATCATCAGGGGGC
AGCCTGTCTCCACTGCAGTCTCCGCCCCTAACACGGTTTCCTCAACACCTGGGCAGAAAAGCTTAACTTCAGCAACGTCCACTTCAAATA
TACAGTCTTCAGCCTCACAACCCCCTCGCCCCCAACAAGGACAAGTGAAGCTCACCATGGCTCAACTTACTCAGTTAACACAGGGCCACG
GTGGCAATCAAGGTTTGACAGTAGTAATTCAAGGACAAGGTCAAACTACTGGACAGTTGCAGTTGATACCTCAAGGGGTGACTGTACTCC
CAGGCCCAGGCCAGCAGCTAATGCAAGCTGCAATGCCAAATGGTACTGTTCAGCGATTCCTCTTTACCCCATTGGCAACAACAGCCACCA
CAGCCAGCACCACCACCACCACTGTTTCCACGACAGCAGCAGGTACAGGTGAACAAAGGCAGAGTAAACTGTCACCCCAGATGCAGGTAC
ATCAAGACAAAACCCTGCCACCAGCTCAGTCATCAAGTGTGGGTCCAGCAGAAGCCCAGCCACAGACTGCTCAGCCTTCAGCTCAGCCCC
AGCCCCAAACCCAGCCCCAGTCCCCAGCTCAGCCTGAAGTTCAGACTCAGCCTGAAGTTCAGACCCAAACAACTGTTTCATCCCATGTCC
CTTCTGAAGCACAACCCACCCACGCACAGTCATCCAAGCCCCAAGTTGCAGCACAGTCTCAGCCTCAAAGTAATGTCCAAGGACAGTCTC
CTGTTCGTGTCCAAAGTCCATCACAGACTCGAATACGTCCATCAACTCCATCCCAACTGTCTCCTGGACAACAATCCCAGGTTCAGACTA
CAACCTCACAACCGATTCCAATTCAACCACATACATCTCTTCAGATACCTTCCCAAGGCCAGCCACAGTCACAACCCCAGGTACAGTCTT
CAACTCAAACTCTTTCATCAGGACAAACTTTAAATCAAGTTACTGTTTCATCCCCATCCCGTCCTCAGCTACAAATACAGCAGCCACAGC
CCCAAGTCATTGCTGTGCCTCAGCTGCAACAACAAGTCCAGGTTCTCTCTCAGATCCAGTCACAGGTTGTGGCTCAGATACAGGCTCAGC
AAAGTGGTGTGCCCCAGCAAATCAAACTCCAGTTACCTATCCAAATTCAGCAAAGCAGTGCTGTGCAGACTCACCAGATTCAGAATGTGG
TTACAGTGCAGGCAGCCAGTGTGCAAGAGCAGTTGCAAAGGGTTCAGCAACTCAGGGATCAGCAGCAAAAGAAGAAACAGCAACAGATAG
AAATTAAGCGTGAACACACCCTCCAAGCTTCTAATCAAAGTGAAATCATTCAGAAACAGGTGGTGATGAAGCATAATGCTGTAATAGAAC
ATTTAAAACAGAAAAAGAGCATGACTCCAGCTGAAAGAGAAGAGAATCAAAGAATGATTGTCTGTAACCAGGTGATGAAGTATATTTTGG
ATAAGATAGATAAAGAAGAAAAACAGGCAGCAAAAAAACGGAAGCGTGAAGAGAGTGTGGAGCAGAAACGTAGCAAGCAGAATGCCACTA
AGCTGTCAGCTCTGCTCTTCAAGCACAAAGAGCAGCTCAGAGCCGAGATCCTGAAGAAGAGAGCACTCCTGGACAAGGATCTGCAAATTG
AAGTGCAGGAAGAGCTGAAGAGAGACCTGAAAATTAAGAAAGAAAAAGACCTGATGCAGTTGGCTCAGGCCACAGCAGTAGCTGCACCCT
GCCCCCCAGTGACACCAGCTCCTCCAGCCCCTCCAGCCCCTCCACCTTCACCTCCCCCTCCACCTGCTGTGCAACACACAGGCCTTCTGT
CCACGCCCACCTTACCTGCTGCTTCCCAGAAGAGGAAGCGGGAAGAGGAAAAAGACTCCAGCTCAAAGTCCAAGAAAAAGAAAATGATCT
CTACTACCTCAAAGGAAACTAAGAAGGACACAAAGCTTTACTGTATCTGTAAAACGCCTTATGATGAATCTAAATTTTATATTGGCTGTG
ATCGGTGTCAGAATTGGTACCATGGGCGCTGCGTTGGCATCTTGCAAAGTGAGGCAGAGCTCATTGATGAGTATGTCTGTCCACAGTGCC
AGTCAACAGAGGATGCCATGACAGTGCTCACGCCACTAACAGAGAAGGATTATGAGGGGTTGAAGAGGGTGCTCCGTTCCTTACAGGCCC
ATAAGATGGCCTGGCCTTTCCTTGAACCAGTAGACCCTAATGATGCACCAGATTATTATGGTGTTATTAAGGAACCTATGGACCTTGCCA
CCATGGAAGAAAGAGTACAAAGACGATATTATGAAAAGCTGACGGAATTTGTGGCAGATATGACCAAAATTTTTGATAACTGTCGTTACT
ACAATCCAAGTGACTCCCCATTTTACCAGTGTGCAGAAGTTCTCGAATCATTCTTTGTACAGAAATTGAAAGGCTTCAAAGCTAGCAGGT
CTCATAACAACAAACTGCAGTCTACAGCTTCTTAAAGTTCAGCGTGTTAACCTAACATAAAACACAGCAAGAATCTGGTTGTCTGAACTA
TTTTAAATTAAGGAGCCAGATGTTTTTAGTCAGGCTATCCTGACAAGACTTGACCTAAACTTCGTTTTTATTGGTCATAACAGTCCAATT
ATATTCTTGGCCAATTTTGTCCAACGGACAAGAAAAAAGCAAAGTCAACGACACCATTATCTTGTCAAGATCAGATGGTTTTACTATTGT
GGCAGAAGCGAGAAAACTTTGTTTATTGAAAAAAAAAGAAAAAGAAAGCAAGAAAAAAAGATACTATGGGGTCAAGTGTAACTCCATGGA
AATGCCACGTCTGCTCTTCAGTGAAGAAGCTGGTTTAGAGTCTCACAGAAAACTTTTGACTGTATTTATTTATTGTTGCAAAAAAGACGC
TTTTTTATTGCTGCCCTCATTTGTCAGCTAATTATTTTTTCTTATAAAATCCAGCCCCGGTTACATATAATCATCTGTATCTTATCATGA
TTCCTGTAGGTAAAAGTACAAGACGACCTCTAGATGTCTTTTCTTTCTATGAAAGGAGCTGCTATGTACACATGTGCACACACACACAAC
TGGGAATCAACAATGAGTTTATTGTTCATGGTAGATTAAAATTAAGCTTGCATAAAGGTTGGGCTAAGTGGTCCTGGACTACAGACTCTG
TTGCCTTGAATATAACAGTACAATTTGTCAATTACTCTGCACCAGGCTAAAATGAGTAAAATCTATTTGAAGGTATCTTGTTTGTAAACA
TTTGTCAGATTCTAATTTTTTTCTTTTGTATTAAAATTCAACTATGGATGTATATGAAACAAAATAAATGGAGATAATTTTTCTCCCACA

>64664_64664_9_PGS1-BPTF_PGS1_chr17_76400170_ENST00000329897_BPTF_chr17_65916130_ENST00000306378_length(amino acids)=1533AA_BP=422
MRRDPCSGGDCWASCLAAQGWPRSWDACPTASAGTGTASAGAVPQVTSPPCCLCPEGVHRFQWIRNLVPEFGVSSSHVRVLSSPAEFFEL
MKVDCLESTLEKSLQAKFPSNLKVSILLDFTRGSRGRKNSRTMLLPLLRRFPEQVRVSLFHTPHLRGLLRLLIPERFNETIGLQHIKVYL
FDNSVILSGANLSDSYFTNRQDRYVFLQDCAEIADFFTELVDAVGDVSLQLQGDDTVQVVDGMVHPYKGDRAEYCKAANKRVMDVINSAR
TRQQMLHAQTFHSNSLLTQEDAAAAGDRRPAPDTWIYPLIQMKPFEIQIDEIVTETLLTEAERGAKVYLTTGYFNLTQAYMDLVLGTRAE
YQILLASPEVNGFFGAKGVAGAIPAAYVHIERQFFSEVCSLGQQERVQLQEYWRRGWTFHAKETSETEITTTEIIKRRDVGPYGIRSEYC
IRKIICPIGVPETPKETPTPQRKGLRSSALRPKRPETPKQTGPVIIETWVAEEELELWEIRAFAERVEKEKAQAVEQQAKKRLEQQKPTV
IATSTTSPTSSTTSTISPAQKVMVAPISGSVTTGTKMVLTTKVGSPATVTFQQNKNFHQTFATWVKQGQSNSGVVQVQQKVLGIIPSSTG
TSQQTFTSFQPRTATVTIRPNTSGSGGTTSNSQVITGPQIRPGMTVIRTPLQQSTLGKAIIRTPVMVQPGAPQQVMTQIIRGQPVSTAVS
APNTVSSTPGQKSLTSATSTSNIQSSASQPPRPQQGQVKLTMAQLTQLTQGHGGNQGLTVVIQGQGQTTGQLQLIPQGVTVLPGPGQQLM
QAAMPNGTVQRFLFTPLATTATTASTTTTTVSTTAAGTGEQRQSKLSPQMQVHQDKTLPPAQSSSVGPAEAQPQTAQPSAQPQPQTQPQS
PAQPEVQTQPEVQTQTTVSSHVPSEAQPTHAQSSKPQVAAQSQPQSNVQGQSPVRVQSPSQTRIRPSTPSQLSPGQQSQVQTTTSQPIPI
QPHTSLQIPSQGQPQSQPQVQSSTQTLSSGQTLNQVTVSSPSRPQLQIQQPQPQVIAVPQLQQQVQVLSQIQSQVVAQIQAQQSGVPQQI
KLQLPIQIQQSSAVQTHQIQNVVTVQAASVQEQLQRVQQLRDQQQKKKQQQIEIKREHTLQASNQSEIIQKQVVMKHNAVIEHLKQKKSM
TPAEREENQRMIVCNQVMKYILDKIDKEEKQAAKKRKREESVEQKRSKQNATKLSALLFKHKEQLRAEILKKRALLDKDLQIEVQEELKR
DLKIKKEKDLMQLAQATAVAAPCPPVTPAPPAPPAPPPSPPPPPAVQHTGLLSTPTLPAASQKRKREEEKDSSSKSKKKKMISTTSKETK
KDTKLYCICKTPYDESKFYIGCDRCQNWYHGRCVGILQSEAELIDEYVCPQCQSTEDAMTVLTPLTEKDYEGLKRVLRSLQAHKMAWPFL
EPVDPNDAPDYYGVIKEPMDLATMEERVQRRYYEKLTEFVADMTKIFDNCRYYNPSDSPFYQCAEVLESFFVQKLKGFKASRSHNNKLQS

--------------------------------------------------------------
>64664_64664_10_PGS1-BPTF_PGS1_chr17_76400170_ENST00000329897_BPTF_chr17_65916130_ENST00000321892_length(transcript)=6715nt_BP=1290nt
CTCCATGGCGGTGGCGGCGGCAGCTGCGGCGGGACCCGTGTTCTGGAGGCGACTGCTGGGCCTCCTGCCTGGCCGCCCAGGGCTGGCCGC
GCTCCTGGGACGCCTGTCCGACCGCCTCGGCAGGAACCGGGACCGCCAGCGCAGGAGCTGTTCCCCAGGTCACCTCCCCACCTTGCTGCC
TGTGTCCAGAAGGCGTGCACCGGTTCCAGTGGATCAGAAACCTGGTTCCAGAATTTGGAGTCTCCAGTTCTCACGTTAGGGTGCTTTCTT
CCCCGGCAGAGTTTTTCGAGCTCATGAAGGTGGACTGCCTGGAAAGTACTCTAGAAAAGTCACTCCAAGCAAAGTTTCCTTCAAATCTCA
AGGTCTCCATTCTCTTAGACTTCACGCGGGGCTCACGAGGCCGGAAGAACTCCCGCACAATGCTGCTCCCACTCCTGCGGAGGTTCCCAG
AGCAGGTCCGAGTCTCCCTCTTTCACACGCCGCACCTCCGTGGGCTGCTTCGGCTCCTCATCCCTGAGCGCTTCAACGAGACCATCGGCC
TCCAGCACATTAAGGTGTACCTCTTCGACAACAGCGTCATCTTGAGCGGTGCAAACCTGAGTGACTCCTACTTCACCAACCGCCAGGACC
GCTACGTGTTCCTGCAGGACTGTGCGGAGATTGCCGACTTCTTCACGGAGCTGGTGGACGCGGTGGGGGATGTGTCCCTGCAGCTGCAGG
GGGACGACACGGTGCAGGTGGTGGATGGGATGGTGCATCCTTACAAAGGGGACCGGGCCGAGTACTGCAAGGCAGCCAATAAGAGGGTCA
TGGATGTGATCAACTCAGCCAGGACCCGCCAGCAGATGCTGCATGCCCAGACCTTCCACAGCAACTCTCTTTTGACCCAGGAAGATGCAG
CAGCTGCTGGGGATCGCAGACCAGCCCCTGACACCTGGATTTATCCGCTGATTCAGATGAAGCCCTTCGAGATTCAAATCGATGAGATTG
TCACTGAGACCCTGTTGACTGAGGCGGAGCGCGGGGCAAAGGTCTACCTCACCACTGGCTATTTCAACCTGACCCAGGCCTACATGGACC
TGGTCTTGGGCACTCGGGCTGAGTACCAGATCCTGCTGGCCTCACCAGAGGTGAATGGCTTCTTTGGGGCCAAGGGGGTGGCCGGCGCCA
TCCCAGCGGCCTATGTGCACATCGAGCGACAGTTCTTCAGTGAGGTGTGCAGCCTGGGACAGCAGGAGCGGGTCCAGCTTCAGGAGTACT
GGCGGAGGGGCTGGACGTTCCACGCCAAAGAAACATCCGAAACTGAAATCACAACAACAGAAATAATTAAGAGGAGAGATGTTGGTCCTT
ATGGCATTCGATCTGAATATTGTATCAGGAAAATCATTTGTCCCATTGGAGTTCCAGAAACACCAAAAGAAACGCCTACACCTCAGAGGA
AAGGCCTTCGATCAAGTGCACTGCGGCCAAAGAGACCAGAAACGCCCAAGCAAACTGGCCCTGTTATTATTGAAACCTGGGTAGCAGAAG
AAGAACTGGAATTGTGGGAGATCAGGGCATTTGCTGAGAGAGTGGAGAAAGAAAAGGCACAAGCAGTTGAGCAACAGGCTAAGAAACGAC
TGGAGCAGCAGAAGCCGACAGTGATTGCAACTTCCACTACTTCCCCAACAAGCAGTACAACCAGCACCATCTCTCCAGCACAGAAGGTTA
TGGTGGCCCCCATAAGTGGCTCAGTTACAACTGGAACCAAAATGGTACTAACTACTAAAGTTGGATCTCCAGCTACAGTAACATTCCAAC
AAAACAAGAACTTTCATCAAACCTTTGCTACATGGGTTAAGCAAGGCCAGTCAAATTCAGGCGTTGTTCAAGTACAGCAGAAAGTCCTGG
GTATCATTCCATCAAGTACAGGTACCAGTCAGCAAACCTTTACTTCATTCCAGCCCAGGACAGCAACAGTCACAATTAGGCCCAATACCT
CAGGCTCTGGAGGAACCACAAGCAATTCACAAGTAATCACAGGGCCTCAGATTCGCCCTGGTATGACCGTGATTAGAACACCACTCCAAC
AGTCAACACTAGGAAAGGCAATTATTCGAACACCTGTGATGGTACAGCCAGGTGCTCCTCAGCAAGTGATGACTCAAATCATCAGGGGGC
AGCCTGTCTCCACTGCAGTCTCCGCCCCTAACACGGTTTCCTCAACACCTGGGCAGAAAAGCTTAACTTCAGCAACGTCCACTTCAAATA
TACAGTCTTCAGCCTCACAACCCCCTCGCCCCCAACAAGGACAAGTGAAGCTCACCATGGCTCAACTTACTCAGTTAACACAGGGCCACG
GTGGCAATCAAGGTTTGACAGTAGTAATTCAAGGACAAGGTCAAACTACTGGACAGTTGCAGTTGATACCTCAAGGGGTGACTGTACTCC
CAGGCCCAGGCCAGCAGCTAATGCAAGCTGCAATGCCAAATGGTACTGTTCAGCGATTCCTCTTTACCCCATTGGCAACAACAGCCACCA
CAGCCAGCACCACCACCACCACTGTTTCCACGACAGCAGCAGGTACAGGTGAACAAAGGCAGAGTAAACTGTCACCCCAGATGCAGGTAC
ATCAAGACAAAACCCTGCCACCAGCTCAGTCATCAAGTGTGGGTCCAGCAGAAGCCCAGCCACAGACTGCTCAGCCTTCAGCTCAGCCCC
AGCCCCAAACCCAGCCCCAGTCCCCAGCTCAGCCTGAAGTTCAGACTCAGCCTGAAGTTCAGACCCAAACAACTGTTTCATCCCATGTCC
CTTCTGAAGCACAACCCACCCACGCACAGTCATCCAAGCCCCAAGTTGCAGCACAGTCTCAGCCTCAAAGTAATGTCCAAGGACAGTCTC
CTGTTCGTGTCCAAAGTCCATCACAGACTCGAATACGTCCATCAACTCCATCCCAACTGTCTCCTGGACAACAATCCCAGGTTCAGACTA
CAACCTCACAACCGATTCCAATTCAACCACATACATCTCTTCAGATACCTTCCCAAGGCCAGCCACAGTCACAACCCCAGGTACAGTCTT
CAACTCAAACTCTTTCATCAGGACAAACTTTAAATCAAGTTACTGTTTCATCCCCATCCCGTCCTCAGCTACAAATACAGCAGCCACAGC
CCCAAGTCATTGCTGTGCCTCAGCTGCAACAACAAGTCCAGGTTCTCTCTCAGATCCAGTCACAGGTTGTGGCTCAGATACAGGCTCAGC
AAAGTGGTGTGCCCCAGCAAATCAAACTCCAGTTACCTATCCAAATTCAGCAAAGCAGTGCTGTGCAGACTCACCAGATTCAGAATGTGG
TTACAGTGCAGGCAGCCAGTGTGCAAGAGCAGTTGCAAAGGGTTCAGCAACTCAGGGATCAGCAGCAAAAGAAGAAACAGCAACAGATAG
AAATTAAGCGTGAACACACCCTCCAAGCTTCTAATCAAAGTGAAATCATTCAGAAACAGGTGGTGATGAAGCATAATGCTGTAATAGAAC
ATTTAAAACAGAAAAAGAGCATGACTCCAGCTGAAAGAGAAGAGAATCAAAGAATGATTGTCTGTAACCAGGTGATGAAGTATATTTTGG
ATAAGATAGATAAAGAAGAAAAACAGGCAGCAAAAAAACGGAAGCGTGAAGAGAGTGTGGAGCAGAAACGTAGCAAGCAGAATGCCACTA
AGCTGTCAGCTCTGCTCTTCAAGCACAAAGAGCAGCTCAGAGCCGAGATCCTGAAGAAGAGAGCACTCCTGGACAAGGATCTGCAAATTG
AAGTGCAGGAAGAGCTGAAGAGAGACCTGAAAATTAAGAAAGAAAAAGACCTGATGCAGTTGGCTCAGGCCACAGCAGTAGCTGCACCCT
GCCCCCCAGTGACACCAGCTCCTCCAGCCCCTCCAGCCCCTCCACCTTCACCTCCCCCTCCACCTGCTGTGCAACACACAGGCCTTCTGT
CCACGCCCACCTTACCTGCTGCTTCCCAGAAGAGGAAGCGGGAAGAGGAAAAAGACTCCAGCTCAAAGTCCAAGAAAAAGAAAATGATCT
CTACTACCTCAAAGGAAACTAAGAAGGACACAAAGCTTTACTGTATCTGTAAAACGCCTTATGATGAATCTAAATTTTATATTGGCTGTG
ATCGGTGTCAGAATTGGTACCATGGGCGCTGCGTTGGCATCTTGCAAAGTGAGGCAGAGCTCATTGATGAGTATGTCTGTCCACAGTGCC
AGTCAACAGAGGATGCCATGACAGTGCTCACGCCACTAACAGAGAAGGATTATGAGGGGTTGAAGAGGGTGCTCCGTTCCTTACAGGCCC
ATAAGATGGCCTGGCCTTTCCTTGAACCAGTAGACCCTAATGATGCACCAGATTATTATGGTGTTATTAAGGAACCTATGGACCTTGCCA
CCATGGAAGAAAGAGTACAAAGACGATATTATGAAAAGCTGACGGAATTTGTGGCAGATATGACCAAAATTTTTGATAACTGTCGTTACT
ACAATCCAAGTGACTCCCCATTTTACCAGTGTGCAGAAGTTCTCGAATCATTCTTTGTACAGAAATTGAAAGGCTTCAAAGCTAGCAGGT
CTCATAACAACAAACTGCAGTCTACAGCTTCTTAAAGTTCAGCGTGTTAACCTAACATAAAACACAGCAAGAATCTGGTTGTCTGAACTA
TTTTAAATTAAGGAGCCAGATGTTTTTAGTCAGGCTATCCTGACAAGACTTGACCTAAACTTCGTTTTTATTGGTCATAACAGTCCAATT
ATATTCTTGGCCAATTTTGTCCAACGGACAAGAAAAAAGCAAAGTCAACGACACCATTATCTTGTCAAGATCAGATGGTTTTACTATTGT
GGCAGAAGCGAGAAAACTTTGTTTATTGAAAAAAAAAGAAAAAGAAAGCAAGAAAAAAAGATACTATGGGGTCAAGTGTAACTCCATGGA
AATGCCACGTCTGCTCTTCAGTGAAGAAGCTGGTTTAGAGTCTCACAGAAAACTTTTGACTGTATTTATTTATTGTTGCAAAAAAGACGC
TTTTTTATTGCTGCCCTCATTTGTCAGCTAATTATTTTTTCTTATAAAATCCAGCCCCGGTTACATATAATCATCTGTATCTTATCATGA
TTCCTGTAGGTAAAAGTACAAGACGACCTCTAGATGTCTTTTCTTTCTATGAAAGGAGCTGCTATGTACACATGTGCACACACACACAAC
TGGGAATCAACAATGAGTTTATTGTTCATGGTAGATTAAAATTAAGCTTGCATAAAGGTTGGGCTAAGTGGTCCTGGACTACAGACTCTG
TTGCCTTGAATATAACAGTACAATTTGTCAATTACTCTGCACCAGGCTAAAATGAGTAAAATCTATTTGAAGGTATCTTGTTTGTAAACA
TTTGTCAGATTCTAATTTTTTTCTTTTGTATTAAAATTCAACTATGGATGTATATGAAACAAAATAAATGGAGATAATTTTTCTCCCACA
GACAGAGGTGTCTTTGAATGTGCGCTAATGATTATCTGTAAGCCTTTGTGGGGAGGGAGGCCTGCAAGGTCATGAAAGGCAGAAGAGTCT
AATTGTGCCTGGATTTCTCCAGGACAGCAGTGGCCCCTCGTTTTATCATTCCCAGTCCATTGTCATCACGTCAGAGAAAAATCTTCAGGG
GTGCTAATCCTGTTGCATCAGTTGATCATACTAACGAGAACGGTAATGCGACAAGATACACATTGCCTTCATCTGTACATTCTGTGATAC
CAGGCAAATTACCAATTACACACAGCTACTTATATTTTATGAAGGGCATTTTTTAGATGACCTCATCCTCTGTGTTATTTGTTGATTGGG
TTTGTTTTCTGTTTGTTGGTTTGTTTGTTTCTTCCACGTAAGGAAAAGTAGTGTAAACAGTAGCGAGAAAATGGAAACCACAGAGGAAGA
TGTATTTTGCATGTTTTTCCTTTCAGTGTTCTTACACGTTGTATCACTGCATTGTGGTAATAGCTTCTATAAAATCTGCCATAGTTGGAT
TATGCAGCTTTGCAAAAATTTTTACTAGATTTTGCACTAACTCATATTAGCTTTGTCCTACCAACTTCTGGAATTTATCTAATTATTGTT
TTTCAAAGTTTCTTTCCTTTTAATGTTTCCCTGCTATGCAAAACCTTTCCCAGACCTCAGTTTCTTAAAAGAAAGATGTTGCTACAGTTC
CCGATTCTTTCTTATTACAGGCTCAGGTGTACAGGTTATTCTGGGTTAATTTTATCTAATGAAGCCCATTCCTTTTTGTACATAAAGATG
TCACTTAAACTTATGCTTACAAACTAAAGACTAATCGCTCAATATGAAAACATGAAAAAATTTTTGCTTAAAGTATTAAGATGGAAGTAG
TTAAATATGGGTTATTTTGTCCTTTTACTTTTTTAAAAAATGTTACATATTGTATGCACTGTGCTGATGCAAGAATTCTACATTTTAATG
AGTTATAAAATTATTCTGCATCTCATCACGTCACAGTATTTCTGTACTATTTATTCATATATATAAATATATATGGGCTTAATCATTTAA
AATTTGTTGCAGCAAGAACTTTCCTACCTGTAGGCAATAGATTGCTATGTTTTTAACAAATTGTGGCAAATTCTAAACAGCAATTCTTTT

>64664_64664_10_PGS1-BPTF_PGS1_chr17_76400170_ENST00000329897_BPTF_chr17_65916130_ENST00000321892_length(amino acids)=1533AA_BP=422
MRRDPCSGGDCWASCLAAQGWPRSWDACPTASAGTGTASAGAVPQVTSPPCCLCPEGVHRFQWIRNLVPEFGVSSSHVRVLSSPAEFFEL
MKVDCLESTLEKSLQAKFPSNLKVSILLDFTRGSRGRKNSRTMLLPLLRRFPEQVRVSLFHTPHLRGLLRLLIPERFNETIGLQHIKVYL
FDNSVILSGANLSDSYFTNRQDRYVFLQDCAEIADFFTELVDAVGDVSLQLQGDDTVQVVDGMVHPYKGDRAEYCKAANKRVMDVINSAR
TRQQMLHAQTFHSNSLLTQEDAAAAGDRRPAPDTWIYPLIQMKPFEIQIDEIVTETLLTEAERGAKVYLTTGYFNLTQAYMDLVLGTRAE
YQILLASPEVNGFFGAKGVAGAIPAAYVHIERQFFSEVCSLGQQERVQLQEYWRRGWTFHAKETSETEITTTEIIKRRDVGPYGIRSEYC
IRKIICPIGVPETPKETPTPQRKGLRSSALRPKRPETPKQTGPVIIETWVAEEELELWEIRAFAERVEKEKAQAVEQQAKKRLEQQKPTV
IATSTTSPTSSTTSTISPAQKVMVAPISGSVTTGTKMVLTTKVGSPATVTFQQNKNFHQTFATWVKQGQSNSGVVQVQQKVLGIIPSSTG
TSQQTFTSFQPRTATVTIRPNTSGSGGTTSNSQVITGPQIRPGMTVIRTPLQQSTLGKAIIRTPVMVQPGAPQQVMTQIIRGQPVSTAVS
APNTVSSTPGQKSLTSATSTSNIQSSASQPPRPQQGQVKLTMAQLTQLTQGHGGNQGLTVVIQGQGQTTGQLQLIPQGVTVLPGPGQQLM
QAAMPNGTVQRFLFTPLATTATTASTTTTTVSTTAAGTGEQRQSKLSPQMQVHQDKTLPPAQSSSVGPAEAQPQTAQPSAQPQPQTQPQS
PAQPEVQTQPEVQTQTTVSSHVPSEAQPTHAQSSKPQVAAQSQPQSNVQGQSPVRVQSPSQTRIRPSTPSQLSPGQQSQVQTTTSQPIPI
QPHTSLQIPSQGQPQSQPQVQSSTQTLSSGQTLNQVTVSSPSRPQLQIQQPQPQVIAVPQLQQQVQVLSQIQSQVVAQIQAQQSGVPQQI
KLQLPIQIQQSSAVQTHQIQNVVTVQAASVQEQLQRVQQLRDQQQKKKQQQIEIKREHTLQASNQSEIIQKQVVMKHNAVIEHLKQKKSM
TPAEREENQRMIVCNQVMKYILDKIDKEEKQAAKKRKREESVEQKRSKQNATKLSALLFKHKEQLRAEILKKRALLDKDLQIEVQEELKR
DLKIKKEKDLMQLAQATAVAAPCPPVTPAPPAPPAPPPSPPPPPAVQHTGLLSTPTLPAASQKRKREEEKDSSSKSKKKKMISTTSKETK
KDTKLYCICKTPYDESKFYIGCDRCQNWYHGRCVGILQSEAELIDEYVCPQCQSTEDAMTVLTPLTEKDYEGLKRVLRSLQAHKMAWPFL
EPVDPNDAPDYYGVIKEPMDLATMEERVQRRYYEKLTEFVADMTKIFDNCRYYNPSDSPFYQCAEVLESFFVQKLKGFKASRSHNNKLQS

--------------------------------------------------------------
>64664_64664_11_PGS1-BPTF_PGS1_chr17_76400170_ENST00000329897_BPTF_chr17_65916130_ENST00000335221_length(transcript)=6286nt_BP=1290nt
CTCCATGGCGGTGGCGGCGGCAGCTGCGGCGGGACCCGTGTTCTGGAGGCGACTGCTGGGCCTCCTGCCTGGCCGCCCAGGGCTGGCCGC
GCTCCTGGGACGCCTGTCCGACCGCCTCGGCAGGAACCGGGACCGCCAGCGCAGGAGCTGTTCCCCAGGTCACCTCCCCACCTTGCTGCC
TGTGTCCAGAAGGCGTGCACCGGTTCCAGTGGATCAGAAACCTGGTTCCAGAATTTGGAGTCTCCAGTTCTCACGTTAGGGTGCTTTCTT
CCCCGGCAGAGTTTTTCGAGCTCATGAAGGTGGACTGCCTGGAAAGTACTCTAGAAAAGTCACTCCAAGCAAAGTTTCCTTCAAATCTCA
AGGTCTCCATTCTCTTAGACTTCACGCGGGGCTCACGAGGCCGGAAGAACTCCCGCACAATGCTGCTCCCACTCCTGCGGAGGTTCCCAG
AGCAGGTCCGAGTCTCCCTCTTTCACACGCCGCACCTCCGTGGGCTGCTTCGGCTCCTCATCCCTGAGCGCTTCAACGAGACCATCGGCC
TCCAGCACATTAAGGTGTACCTCTTCGACAACAGCGTCATCTTGAGCGGTGCAAACCTGAGTGACTCCTACTTCACCAACCGCCAGGACC
GCTACGTGTTCCTGCAGGACTGTGCGGAGATTGCCGACTTCTTCACGGAGCTGGTGGACGCGGTGGGGGATGTGTCCCTGCAGCTGCAGG
GGGACGACACGGTGCAGGTGGTGGATGGGATGGTGCATCCTTACAAAGGGGACCGGGCCGAGTACTGCAAGGCAGCCAATAAGAGGGTCA
TGGATGTGATCAACTCAGCCAGGACCCGCCAGCAGATGCTGCATGCCCAGACCTTCCACAGCAACTCTCTTTTGACCCAGGAAGATGCAG
CAGCTGCTGGGGATCGCAGACCAGCCCCTGACACCTGGATTTATCCGCTGATTCAGATGAAGCCCTTCGAGATTCAAATCGATGAGATTG
TCACTGAGACCCTGTTGACTGAGGCGGAGCGCGGGGCAAAGGTCTACCTCACCACTGGCTATTTCAACCTGACCCAGGCCTACATGGACC
TGGTCTTGGGCACTCGGGCTGAGTACCAGATCCTGCTGGCCTCACCAGAGGTGAATGGCTTCTTTGGGGCCAAGGGGGTGGCCGGCGCCA
TCCCAGCGGCCTATGTGCACATCGAGCGACAGTTCTTCAGTGAGGTGTGCAGCCTGGGACAGCAGGAGCGGGTCCAGCTTCAGGAGTACT
GGCGGAGGGGCTGGACGTTCCACGCCAAAGAAACATCCGAAACTGAAATCACAACAACAGAAATAATTAAGAGGAGAGATGTTGGTCCTT
ATGGCATTCGATCTGAATATTGTATCAGGAAAATCATTTGTCCCATTGGAGTTCCAGAAACACCAAAAGAAACGCCTACACCTCAGAGGA
AAGGCCTTCGATCAAGTGCACTGCGGCCAAAGAGACCAGAAACGCCCAAGCAAACTGGCCCTGTTATTATTGAAACCTGGGTAGCAGAAG
AAGAACTGGAATTGTGGGAGATCAGGGCATTTGCTGAGAGAGTGGAGAAAGAAAAGGCACAAGCAGTTGAGCAACAGGCTAAGAAACGAC
TGGAGCAGCAGAAGCCGACAGTGATTGCAACTTCCACTACTTCCCCAACAAGCAGTACAACCAGCACCATCTCTCCAGCACAGAAGGTTA
TGGTGGCCCCCATAAGTGGCTCAGTTACAACTGGAACCAAAATGGTACTAACTACTAAAGTTGGATCTCCAGCTACAGTAACATTCCAAC
AAAACAAGAACTTTCATCAAACCTTTGCTACATGGGTTAAGCAAGGCCAGTCAAATTCAGGCGTTGTTCAAGTACAGCAGAAAGTCCTGG
GTATCATTCCATCAAGTACAGGTACCAGTCAGCAAACCTTTACTTCATTCCAGCCCAGGACAGCAACAGTCACAATTAGGCCCAATACCT
CAGGCTCTGGAGGAACCACAAGCAATTCACAAGTAATCACAGGGCCTCAGATTCGCCCTGGTATGACCGTGATTAGAACACCACTCCAAC
AGTCAACACTAGGAAAGGCAATTATTCGAACACCTGTGATGGTACAGCCAGGTGCTCCTCAGCAAGTGATGACTCAAATCATCAGGGGGC
AGCCTGTCTCCACTGCAGTCTCCGCCCCTAACACGGTTTCCTCAACACCTGGGCAGAAAAGCTTAACTTCAGCAACGTCCACTTCAAATA
TACAGTCTTCAGCCTCACAACCCCCTCGCCCCCAACAAGGACAAGTGAAGCTCACCATGGCTCAACTTACTCAGTTAACACAGGGCCACG
GTGGCAATCAAGGTTTGACAGTAGTAATTCAAGGACAAGGTCAAACTACTGGACAGTTGCAGTTGATACCTCAAGGGGTGACTGTACTCC
CAGGCCCAGGCCAGCAGCTAATGCAAGCTGCAATGCCAAATGGTACTGTTCAGCGATTCCTCTTTACCCCATTGGCAACAACAGCCACCA
CAGCCAGCACCACCACCACCACTGTTTCCACGACAGCAGCAGGTACAGGTGAACAAAGGCAGAGTAAACTGTCACCCCAGATGCAGGTAC
ATCAAGACAAAACCCTGCCACCAGCTCAGTCATCAAGTGTGGGTCCAGCAGAAGCCCAGCCACAGACTGCTCAGCCTTCAGCTCAGCCCC
AGCCCCAAACCCAGCCCCAGTCCCCAGCTCAGCCTGAAGTTCAGACTCAGCCTGAAGTTCAGACCCAAACAACTGTTTCATCCCATGTCC
CTTCTGAAGCACAACCCACCCACGCACAGTCATCCAAGCCCCAAGTTGCAGCACAGTCTCAGCCTCAAAGTAATGTCCAAGGACAGTCTC
CTGTTCGTGTCCAAAGTCCATCACAGACTCGAATACGTCCATCAACTCCATCCCAACTGTCTCCTGGACAACAATCCCAGGTTCAGACTA
CAACCTCACAACCGATTCCAATTCAACCACATACATCTCTTCAGATACCTTCCCAAGGCCAGCCACAGTCACAACCCCAGGTGGTGATGA
AGCATAATGCTGTAATAGAACATTTAAAACAGAAAAAGAGCATGACTCCAGCTGAAAGAGAAGAGAATCAAAGAATGATTGTCTGTAACC
AGGTGATGAAGTATATTTTGGATAAGATAGATAAAGAAGAAAAACAGGCAGCAAAAAAACGGAAGCGTGAAGAGAGTGTGGAGCAGAAAC
GTAGCAAGCAGAATGCCACTAAGCTGTCAGCTCTGCTCTTCAAGCACAAAGAGCAGCTCAGAGCCGAGATCCTGAAGAAGAGAGCACTCC
TGGACAAGGATCTGCAAATTGAAGTGCAGGAAGAGCTGAAGAGAGACCTGAAAATTAAGAAAGAAAAAGACCTGATGCAGTTGGCTCAGG
CCACAGCAGTAGCTGCACCCTGCCCCCCAGTGACACCAGCTCCTCCAGCCCCTCCAGCCCCTCCACCTTCACCTCCCCCTCCACCTGCTG
TGCAACACACAGGCCTTCTGTCCACGCCCACCTTACCTGCTGCTTCCCAGAAGAGGAAGCGGGAAGAGGAAAAAGACTCCAGCTCAAAGT
CCAAGAAAAAGAAAATGATCTCTACTACCTCAAAGGAAACTAAGAAGGACACAAAGCTTTACTGTATCTGTAAAACGCCTTATGATGAAT
CTAAATTTTATATTGGCTGTGATCGGTGTCAGAATTGGTACCATGGGCGCTGCGTTGGCATCTTGCAAAGTGAGGCAGAGCTCATTGATG
AGTATGTCTGTCCACAGTGCCAGTCAACAGAGGATGCCATGACAGTGCTCACGCCACTAACAGAGAAGGATTATGAGGGGTTGAAGAGGG
TGCTCCGTTCCTTACAGGCCCATAAGATGGCCTGGCCTTTCCTTGAACCAGTAGACCCTAATGATGCACCAGATTATTATGGTGTTATTA
AGGAACCTATGGACCTTGCCACCATGGAAGAAAGAGTACAAAGACGATATTATGAAAAGCTGACGGAATTTGTGGCAGATATGACCAAAA
TTTTTGATAACTGTCGTTACTACAATCCAAGTGACTCCCCATTTTACCAGTGTGCAGAAGTTCTCGAATCATTCTTTGTACAGAAATTGA
AAGGCTTCAAAGCTAGCAGGTCTCATAACAACAAACTGCAGTCTACAGCTTCTTAAAGTTCAGCGTGTTAACCTAACATAAAACACAGCA
AGAATCTGGTTGTCTGAACTATTTTAAATTAAGGAGCCAGATGTTTTTAGTCAGGCTATCCTGACAAGACTTGACCTAAACTTCGTTTTT
ATTGGTCATAACAGTCCAATTATATTCTTGGCCAATTTTGTCCAACGGACAAGAAAAAAGCAAAGTCAACGACACCATTATCTTGTCAAG
ATCAGATGGTTTTACTATTGTGGCAGAAGCGAGAAAACTTTGTTTATTGAAAAAAAAAGAAAAAGAAAGCAAGAAAAAAAGATACTATGG
GGTCAAGTGTAACTCCATGGAAATGCCACGTCTGCTCTTCAGTGAAGAAGCTGGTTTAGAGTCTCACAGAAAACTTTTGACTGTATTTAT
TTATTGTTGCAAAAAAGACGCTTTTTTATTGCTGCCCTCATTTGTCAGCTAATTATTTTTTCTTATAAAATCCAGCCCCGGTTACATATA
ATCATCTGTATCTTATCATGATTCCTGTAGGTAAAAGTACAAGACGACCTCTAGATGTCTTTTCTTTCTATGAAAGGAGCTGCTATGTAC
ACATGTGCACACACACACAACTGGGAATCAACAATGAGTTTATTGTTCATGGTAGATTAAAATTAAGCTTGCATAAAGGTTGGGCTAAGT
GGTCCTGGACTACAGACTCTGTTGCCTTGAATATAACAGTACAATTTGTCAATTACTCTGCACCAGGCTAAAATGAGTAAAATCTATTTG
AAGGTATCTTGTTTGTAAACATTTGTCAGATTCTAATTTTTTTCTTTTGTATTAAAATTCAACTATGGATGTATATGAAACAAAATAAAT
GGAGATAATTTTTCTCCCACAGACAGAGGTGTCTTTGAATGTGCGCTAATGATTATCTGTAAGCCTTTGTGGGGAGGGAGGCCTGCAAGG
TCATGAAAGGCAGAAGAGTCTAATTGTGCCTGGATTTCTCCAGGACAGCAGTGGCCCCTCGTTTTATCATTCCCAGTCCATTGTCATCAC
GTCAGAGAAAAATCTTCAGGGGTGCTAATCCTGTTGCATCAGTTGATCATACTAACGAGAACGGTAATGCGACAAGATACACATTGCCTT
CATCTGTACATTCTGTGATACCAGGCAAATTACCAATTACACACAGCTACTTATATTTTATGAAGGGCATTTTTTAGATGACCTCATCCT
CTGTGTTATTTGTTGATTGGGTTTGTTTTCTGTTTGTTGGTTTGTTTGTTTCTTCCACGTAAGGAAAAGTAGTGTAAACAGTAGCGAGAA
AATGGAAACCACAGAGGAAGATGTATTTTGCATGTTTTTCCTTTCAGTGTTCTTACACGTTGTATCACTGCATTGTGGTAATAGCTTCTA
TAAAATCTGCCATAGTTGGATTATGCAGCTTTGCAAAAATTTTTACTAGATTTTGCACTAACTCATATTAGCTTTGTCCTACCAACTTCT
GGAATTTATCTAATTATTGTTTTTCAAAGTTTCTTTCCTTTTAATGTTTCCCTGCTATGCAAAACCTTTCCCAGACCTCAGTTTCTTAAA
AGAAAGATGTTGCTACAGTTCCCGATTCTTTCTTATTACAGGCTCAGGTGTACAGGTTATTCTGGGTTAATTTTATCTAATGAAGCCCAT
TCCTTTTTGTACATAAAGATGTCACTTAAACTTATGCTTACAAACTAAAGACTAATCGCTCAATATGAAAACATGAAAAAATTTTTGCTT
AAAGTATTAAGATGGAAGTAGTTAAATATGGGTTATTTTGTCCTTTTACTTTTTTAAAAAATGTTACATATTGTATGCACTGTGCTGATG
CAAGAATTCTACATTTTAATGAGTTATAAAATTATTCTGCATCTCATCACGTCACAGTATTTCTGTACTATTTATTCATATATATAAATA
TATATGGGCTTAATCATTTAAAATTTGTTGCAGCAAGAACTTTCCTACCTGTAGGCAATAGATTGCTATGTTTTTAACAAATTGTGGCAA

>64664_64664_11_PGS1-BPTF_PGS1_chr17_76400170_ENST00000329897_BPTF_chr17_65916130_ENST00000335221_length(amino acids)=1390AA_BP=422
MRRDPCSGGDCWASCLAAQGWPRSWDACPTASAGTGTASAGAVPQVTSPPCCLCPEGVHRFQWIRNLVPEFGVSSSHVRVLSSPAEFFEL
MKVDCLESTLEKSLQAKFPSNLKVSILLDFTRGSRGRKNSRTMLLPLLRRFPEQVRVSLFHTPHLRGLLRLLIPERFNETIGLQHIKVYL
FDNSVILSGANLSDSYFTNRQDRYVFLQDCAEIADFFTELVDAVGDVSLQLQGDDTVQVVDGMVHPYKGDRAEYCKAANKRVMDVINSAR
TRQQMLHAQTFHSNSLLTQEDAAAAGDRRPAPDTWIYPLIQMKPFEIQIDEIVTETLLTEAERGAKVYLTTGYFNLTQAYMDLVLGTRAE
YQILLASPEVNGFFGAKGVAGAIPAAYVHIERQFFSEVCSLGQQERVQLQEYWRRGWTFHAKETSETEITTTEIIKRRDVGPYGIRSEYC
IRKIICPIGVPETPKETPTPQRKGLRSSALRPKRPETPKQTGPVIIETWVAEEELELWEIRAFAERVEKEKAQAVEQQAKKRLEQQKPTV
IATSTTSPTSSTTSTISPAQKVMVAPISGSVTTGTKMVLTTKVGSPATVTFQQNKNFHQTFATWVKQGQSNSGVVQVQQKVLGIIPSSTG
TSQQTFTSFQPRTATVTIRPNTSGSGGTTSNSQVITGPQIRPGMTVIRTPLQQSTLGKAIIRTPVMVQPGAPQQVMTQIIRGQPVSTAVS
APNTVSSTPGQKSLTSATSTSNIQSSASQPPRPQQGQVKLTMAQLTQLTQGHGGNQGLTVVIQGQGQTTGQLQLIPQGVTVLPGPGQQLM
QAAMPNGTVQRFLFTPLATTATTASTTTTTVSTTAAGTGEQRQSKLSPQMQVHQDKTLPPAQSSSVGPAEAQPQTAQPSAQPQPQTQPQS
PAQPEVQTQPEVQTQTTVSSHVPSEAQPTHAQSSKPQVAAQSQPQSNVQGQSPVRVQSPSQTRIRPSTPSQLSPGQQSQVQTTTSQPIPI
QPHTSLQIPSQGQPQSQPQVVMKHNAVIEHLKQKKSMTPAEREENQRMIVCNQVMKYILDKIDKEEKQAAKKRKREESVEQKRSKQNATK
LSALLFKHKEQLRAEILKKRALLDKDLQIEVQEELKRDLKIKKEKDLMQLAQATAVAAPCPPVTPAPPAPPAPPPSPPPPPAVQHTGLLS
TPTLPAASQKRKREEEKDSSSKSKKKKMISTTSKETKKDTKLYCICKTPYDESKFYIGCDRCQNWYHGRCVGILQSEAELIDEYVCPQCQ
STEDAMTVLTPLTEKDYEGLKRVLRSLQAHKMAWPFLEPVDPNDAPDYYGVIKEPMDLATMEERVQRRYYEKLTEFVADMTKIFDNCRYY

--------------------------------------------------------------
>64664_64664_12_PGS1-BPTF_PGS1_chr17_76400170_ENST00000329897_BPTF_chr17_65916130_ENST00000424123_length(transcript)=4196nt_BP=1290nt
CTCCATGGCGGTGGCGGCGGCAGCTGCGGCGGGACCCGTGTTCTGGAGGCGACTGCTGGGCCTCCTGCCTGGCCGCCCAGGGCTGGCCGC
GCTCCTGGGACGCCTGTCCGACCGCCTCGGCAGGAACCGGGACCGCCAGCGCAGGAGCTGTTCCCCAGGTCACCTCCCCACCTTGCTGCC
TGTGTCCAGAAGGCGTGCACCGGTTCCAGTGGATCAGAAACCTGGTTCCAGAATTTGGAGTCTCCAGTTCTCACGTTAGGGTGCTTTCTT
CCCCGGCAGAGTTTTTCGAGCTCATGAAGGTGGACTGCCTGGAAAGTACTCTAGAAAAGTCACTCCAAGCAAAGTTTCCTTCAAATCTCA
AGGTCTCCATTCTCTTAGACTTCACGCGGGGCTCACGAGGCCGGAAGAACTCCCGCACAATGCTGCTCCCACTCCTGCGGAGGTTCCCAG
AGCAGGTCCGAGTCTCCCTCTTTCACACGCCGCACCTCCGTGGGCTGCTTCGGCTCCTCATCCCTGAGCGCTTCAACGAGACCATCGGCC
TCCAGCACATTAAGGTGTACCTCTTCGACAACAGCGTCATCTTGAGCGGTGCAAACCTGAGTGACTCCTACTTCACCAACCGCCAGGACC
GCTACGTGTTCCTGCAGGACTGTGCGGAGATTGCCGACTTCTTCACGGAGCTGGTGGACGCGGTGGGGGATGTGTCCCTGCAGCTGCAGG
GGGACGACACGGTGCAGGTGGTGGATGGGATGGTGCATCCTTACAAAGGGGACCGGGCCGAGTACTGCAAGGCAGCCAATAAGAGGGTCA
TGGATGTGATCAACTCAGCCAGGACCCGCCAGCAGATGCTGCATGCCCAGACCTTCCACAGCAACTCTCTTTTGACCCAGGAAGATGCAG
CAGCTGCTGGGGATCGCAGACCAGCCCCTGACACCTGGATTTATCCGCTGATTCAGATGAAGCCCTTCGAGATTCAAATCGATGAGATTG
TCACTGAGACCCTGTTGACTGAGGCGGAGCGCGGGGCAAAGGTCTACCTCACCACTGGCTATTTCAACCTGACCCAGGCCTACATGGACC
TGGTCTTGGGCACTCGGGCTGAGTACCAGATCCTGCTGGCCTCACCAGAGGTGAATGGCTTCTTTGGGGCCAAGGGGGTGGCCGGCGCCA
TCCCAGCGGCCTATGTGCACATCGAGCGACAGTTCTTCAGTGAGGTGTGCAGCCTGGGACAGCAGGAGCGGGTCCAGCTTCAGGAGTACT
GGCGGAGGGGCTGGACGTTCCACGCCAAAGAAACATCCGAAACTGAAATCACAACAACAGAAATAATTAAGAGGAGAGATGTTGGTCCTT
ATGGCATTCGATCTGAATATTGTATCAGGAAAATCATTTGTCCCATTGGAGTTCCAGAAACACCAAAAGAAACGCCTACACCTCAGAGGA
AAGGCCTTCGATCAAGTGCACTGCGGCCAAAGAGACCAGAAACGCCCAAGCAAACTGGCCCTGTTATTATTGAAACCTGGGTAGCAGAAG
AAGAACTGGAATTGTGGGAGATCAGGGCATTTGCTGAGAGAGTGGAGAAAGAAAAGGCACAAGCAGTTGAGCAACAGGCTAAGAAACGAC
TGGAGCAGCAGAAGCCGACAGTGATTGCAACTTCCACTACTTCCCCAACAAGCAGTACAACCAGCACCATCTCTCCAGCACAGAAGGTTA
TGGTGGCCCCCATAAGTGGCTCAGTTACAACTGGAACCAAAATGGTACTAACTACTAAAGTTGGATCTCCAGCTACAGTAACATTCCAAC
AAAACAAGAACTTTCATCAAACCTTTGCTACATGGGTTAAGCAAGGCCAGTCAAATTCAGGCGTTGTTCAAGTACAGCAGAAAGTCCTGG
GTATCATTCCATCAAGTACAGGTACCAGTCAGCAAACCTTTACTTCATTCCAGCCCAGGACAGCAACAGTCACAATTAGGCCCAATACCT
CAGGCTCTGGAGGAACCACAAGCAATTCACAAGTAATCACAGGGCCTCAGATTCGCCCTGGTATGACCGTGATTAGAACACCACTCCAAC
AGTCAACACTAGGAAAGGCAATTATTCGAACACCTGTGATGGTACAGCCAGGTGCTCCTCAGCAAGTGATGACTCAAATCATCAGGGGGC
AGCCTGTCTCCACTGCAGTCTCCGCCCCTAACACGGTTTCCTCAACACCTGGGCAGAAAAGCTTAACTTCAGCAACGTCCACTTCAAATA
TACAGTCTTCAGCCTCACAACCCCCTCGCCCCCAACAAGGACAAGTGAAGCTCACCATGGCTCAACTTACTCAGTTAACACAGGGCCACG
GTGGCAATCAAGGTTTGACAGTAGTAATTCAAGGACAAGGTCAAACTACTGGACAGTTGCAGTTGATACCTCAAGGGGTGACTGTACTCC
CAGGCCCAGGCCAGCAGCTAATGCAAGCTGCAATGCCAAATGGTACTGTTCAGCGATTCCTCTTTACCCCATTGGCAACAACAGCCACCA
CAGCCAGCACCACCACCACCACTGTTTCCACGACAGCAGCAGGTACAGGTGAACAAAGGCAGAGTAAACTGTCACCCCAGATGCAGGTAC
ATCAAGACAAAACCCTGCCACCAGCTCAGTCATCAAGTGTGGGTCCAGCAGAAGCCCAGCCACAGACTGCTCAGCCTTCAGCTCAGCCCC
AGCCCCAAACCCAGCCCCAGTCCCCAGCTCAGCCTGAAGTTCAGACTCAGCCTGAAGTTCAGACCCAAACAACTGTTTCATCCCATGTCC
CTTCTGAAGCACAACCCACCCACGCACAGTCATCCAAGCCCCAAGTTGCAGCACAGTCTCAGCCTCAAAGTAATGTCCAAGGACAGTCTC
CTGTTCGTGTCCAAAGTCCATCACAGACTCGAATACGTCCATCAACTCCATCCCAACTGTCTCCTGGACAACAATCCCAGGTTCAGACTA
CAACCTCACAACCGATTCCAATTCAACCACATACATCTCTTCAGATACCTTCCCAAGGCCAGCCACAGTCACAACCCCAGGTGGTGATGA
AGCATAATGCTGTAATAGAACATTTAAAACAGAAAAAGAGCATGACTCCAGCTGAAAGAGAAGAGAATCAAAGAATGATTGTCTGTAACC
AGGTGATGAAGTATATTTTGGATAAGATAGATAAAGAAGAAAAACAGGCAGCAAAAAAACGGAAGCGTGAAGAGAGTGTGGAGCAGAAAC
GTAGCAAGCAGAATGCCACTAAGCTGTCAGCTCTGCTCTTCAAGCACAAAGAGCAGCTCAGAGCCGAGATCCTGAAGAAGAGAGCACTCC
TGGACAAGGATCTGCAAATTGAAGTGCAGGAAGAGCTGAAGAGAGACCTGAAAATTAAGAAAGAAAAAGACCTGATGCAGTTGGCTCAGG
CCACAGCAGTAGCTGCACCCTGCCCCCCAGTGACACCAGCTCCTCCAGCCCCTCCAGCCCCTCCACCTTCACCTCCCCCTCCACCTGCTG
TGCAACACACAGGCCTTCTGTCCACGCCCACCTTACCTGCTGCTTCCCAGAAGAGGAAGCGGGAAGAGGAAAAAGACTCCAGCTCAAAGT
CCAAGAAAAAGAAAATGATCTCTACTACCTCAAAGGAAACTAAGAAGGACACAAAGCTTTACTGTATCTGTAAAACGCCTTATGATGAAT
CTAAATTTTATATTGGCTGTGATCGGTGTCAGAATTGGTACCATGGGCGCTGCGTTGGCATCTTGCAAAGTGAGGCAGAGCTCATTGATG
AGTATGTCTGTCCACAGTGCCAGTCAACAGAGGATGCCATGACAGTGCTCACGCCACTAACAGAGAAGGATTATGAGGGGTTGAAGAGGG
TGCTCCGTTCCTTACAGGCCCATAAGATGGCCTGGCCTTTCCTTGAACCAGTAGACCCTAATGATGCACCAGATTATTATGGTGTTATTA
AGGAACCTATGGACCTTGCCACCATGGAAGAAAGAGTACAAAGACGATATTATGAAAAGCTGACGGAATTTGTGGCAGATATGACCAAAA
TTTTTGATAACTGTCGTTACTACAATCCAAGTGACTCCCCATTTTACCAGTGTGCAGAAGTTCTCGAATCATTCTTTGTACAGAAATTGA

>64664_64664_12_PGS1-BPTF_PGS1_chr17_76400170_ENST00000329897_BPTF_chr17_65916130_ENST00000424123_length(amino acids)=1391AA_BP=422
MRRDPCSGGDCWASCLAAQGWPRSWDACPTASAGTGTASAGAVPQVTSPPCCLCPEGVHRFQWIRNLVPEFGVSSSHVRVLSSPAEFFEL
MKVDCLESTLEKSLQAKFPSNLKVSILLDFTRGSRGRKNSRTMLLPLLRRFPEQVRVSLFHTPHLRGLLRLLIPERFNETIGLQHIKVYL
FDNSVILSGANLSDSYFTNRQDRYVFLQDCAEIADFFTELVDAVGDVSLQLQGDDTVQVVDGMVHPYKGDRAEYCKAANKRVMDVINSAR
TRQQMLHAQTFHSNSLLTQEDAAAAGDRRPAPDTWIYPLIQMKPFEIQIDEIVTETLLTEAERGAKVYLTTGYFNLTQAYMDLVLGTRAE
YQILLASPEVNGFFGAKGVAGAIPAAYVHIERQFFSEVCSLGQQERVQLQEYWRRGWTFHAKETSETEITTTEIIKRRDVGPYGIRSEYC
IRKIICPIGVPETPKETPTPQRKGLRSSALRPKRPETPKQTGPVIIETWVAEEELELWEIRAFAERVEKEKAQAVEQQAKKRLEQQKPTV
IATSTTSPTSSTTSTISPAQKVMVAPISGSVTTGTKMVLTTKVGSPATVTFQQNKNFHQTFATWVKQGQSNSGVVQVQQKVLGIIPSSTG
TSQQTFTSFQPRTATVTIRPNTSGSGGTTSNSQVITGPQIRPGMTVIRTPLQQSTLGKAIIRTPVMVQPGAPQQVMTQIIRGQPVSTAVS
APNTVSSTPGQKSLTSATSTSNIQSSASQPPRPQQGQVKLTMAQLTQLTQGHGGNQGLTVVIQGQGQTTGQLQLIPQGVTVLPGPGQQLM
QAAMPNGTVQRFLFTPLATTATTASTTTTTVSTTAAGTGEQRQSKLSPQMQVHQDKTLPPAQSSSVGPAEAQPQTAQPSAQPQPQTQPQS
PAQPEVQTQPEVQTQTTVSSHVPSEAQPTHAQSSKPQVAAQSQPQSNVQGQSPVRVQSPSQTRIRPSTPSQLSPGQQSQVQTTTSQPIPI
QPHTSLQIPSQGQPQSQPQVVMKHNAVIEHLKQKKSMTPAEREENQRMIVCNQVMKYILDKIDKEEKQAAKKRKREESVEQKRSKQNATK
LSALLFKHKEQLRAEILKKRALLDKDLQIEVQEELKRDLKIKKEKDLMQLAQATAVAAPCPPVTPAPPAPPAPPPSPPPPPAVQHTGLLS
TPTLPAASQKRKREEEKDSSSKSKKKKMISTTSKETKKDTKLYCICKTPYDESKFYIGCDRCQNWYHGRCVGILQSEAELIDEYVCPQCQ
STEDAMTVLTPLTEKDYEGLKRVLRSLQAHKMAWPFLEPVDPNDAPDYYGVIKEPMDLATMEERVQRRYYEKLTEFVADMTKIFDNCRYY

--------------------------------------------------------------
>64664_64664_13_PGS1-BPTF_PGS1_chr17_76400170_ENST00000329897_BPTF_chr17_65916131_ENST00000306378_length(transcript)=5490nt_BP=1290nt
CTCCATGGCGGTGGCGGCGGCAGCTGCGGCGGGACCCGTGTTCTGGAGGCGACTGCTGGGCCTCCTGCCTGGCCGCCCAGGGCTGGCCGC
GCTCCTGGGACGCCTGTCCGACCGCCTCGGCAGGAACCGGGACCGCCAGCGCAGGAGCTGTTCCCCAGGTCACCTCCCCACCTTGCTGCC
TGTGTCCAGAAGGCGTGCACCGGTTCCAGTGGATCAGAAACCTGGTTCCAGAATTTGGAGTCTCCAGTTCTCACGTTAGGGTGCTTTCTT
CCCCGGCAGAGTTTTTCGAGCTCATGAAGGTGGACTGCCTGGAAAGTACTCTAGAAAAGTCACTCCAAGCAAAGTTTCCTTCAAATCTCA
AGGTCTCCATTCTCTTAGACTTCACGCGGGGCTCACGAGGCCGGAAGAACTCCCGCACAATGCTGCTCCCACTCCTGCGGAGGTTCCCAG
AGCAGGTCCGAGTCTCCCTCTTTCACACGCCGCACCTCCGTGGGCTGCTTCGGCTCCTCATCCCTGAGCGCTTCAACGAGACCATCGGCC
TCCAGCACATTAAGGTGTACCTCTTCGACAACAGCGTCATCTTGAGCGGTGCAAACCTGAGTGACTCCTACTTCACCAACCGCCAGGACC
GCTACGTGTTCCTGCAGGACTGTGCGGAGATTGCCGACTTCTTCACGGAGCTGGTGGACGCGGTGGGGGATGTGTCCCTGCAGCTGCAGG
GGGACGACACGGTGCAGGTGGTGGATGGGATGGTGCATCCTTACAAAGGGGACCGGGCCGAGTACTGCAAGGCAGCCAATAAGAGGGTCA
TGGATGTGATCAACTCAGCCAGGACCCGCCAGCAGATGCTGCATGCCCAGACCTTCCACAGCAACTCTCTTTTGACCCAGGAAGATGCAG
CAGCTGCTGGGGATCGCAGACCAGCCCCTGACACCTGGATTTATCCGCTGATTCAGATGAAGCCCTTCGAGATTCAAATCGATGAGATTG
TCACTGAGACCCTGTTGACTGAGGCGGAGCGCGGGGCAAAGGTCTACCTCACCACTGGCTATTTCAACCTGACCCAGGCCTACATGGACC
TGGTCTTGGGCACTCGGGCTGAGTACCAGATCCTGCTGGCCTCACCAGAGGTGAATGGCTTCTTTGGGGCCAAGGGGGTGGCCGGCGCCA
TCCCAGCGGCCTATGTGCACATCGAGCGACAGTTCTTCAGTGAGGTGTGCAGCCTGGGACAGCAGGAGCGGGTCCAGCTTCAGGAGTACT
GGCGGAGGGGCTGGACGTTCCACGCCAAAGAAACATCCGAAACTGAAATCACAACAACAGAAATAATTAAGAGGAGAGATGTTGGTCCTT
ATGGCATTCGATCTGAATATTGTATCAGGAAAATCATTTGTCCCATTGGAGTTCCAGAAACACCAAAAGAAACGCCTACACCTCAGAGGA
AAGGCCTTCGATCAAGTGCACTGCGGCCAAAGAGACCAGAAACGCCCAAGCAAACTGGCCCTGTTATTATTGAAACCTGGGTAGCAGAAG
AAGAACTGGAATTGTGGGAGATCAGGGCATTTGCTGAGAGAGTGGAGAAAGAAAAGGCACAAGCAGTTGAGCAACAGGCTAAGAAACGAC
TGGAGCAGCAGAAGCCGACAGTGATTGCAACTTCCACTACTTCCCCAACAAGCAGTACAACCAGCACCATCTCTCCAGCACAGAAGGTTA
TGGTGGCCCCCATAAGTGGCTCAGTTACAACTGGAACCAAAATGGTACTAACTACTAAAGTTGGATCTCCAGCTACAGTAACATTCCAAC
AAAACAAGAACTTTCATCAAACCTTTGCTACATGGGTTAAGCAAGGCCAGTCAAATTCAGGCGTTGTTCAAGTACAGCAGAAAGTCCTGG
GTATCATTCCATCAAGTACAGGTACCAGTCAGCAAACCTTTACTTCATTCCAGCCCAGGACAGCAACAGTCACAATTAGGCCCAATACCT
CAGGCTCTGGAGGAACCACAAGCAATTCACAAGTAATCACAGGGCCTCAGATTCGCCCTGGTATGACCGTGATTAGAACACCACTCCAAC
AGTCAACACTAGGAAAGGCAATTATTCGAACACCTGTGATGGTACAGCCAGGTGCTCCTCAGCAAGTGATGACTCAAATCATCAGGGGGC
AGCCTGTCTCCACTGCAGTCTCCGCCCCTAACACGGTTTCCTCAACACCTGGGCAGAAAAGCTTAACTTCAGCAACGTCCACTTCAAATA
TACAGTCTTCAGCCTCACAACCCCCTCGCCCCCAACAAGGACAAGTGAAGCTCACCATGGCTCAACTTACTCAGTTAACACAGGGCCACG
GTGGCAATCAAGGTTTGACAGTAGTAATTCAAGGACAAGGTCAAACTACTGGACAGTTGCAGTTGATACCTCAAGGGGTGACTGTACTCC
CAGGCCCAGGCCAGCAGCTAATGCAAGCTGCAATGCCAAATGGTACTGTTCAGCGATTCCTCTTTACCCCATTGGCAACAACAGCCACCA
CAGCCAGCACCACCACCACCACTGTTTCCACGACAGCAGCAGGTACAGGTGAACAAAGGCAGAGTAAACTGTCACCCCAGATGCAGGTAC
ATCAAGACAAAACCCTGCCACCAGCTCAGTCATCAAGTGTGGGTCCAGCAGAAGCCCAGCCACAGACTGCTCAGCCTTCAGCTCAGCCCC
AGCCCCAAACCCAGCCCCAGTCCCCAGCTCAGCCTGAAGTTCAGACTCAGCCTGAAGTTCAGACCCAAACAACTGTTTCATCCCATGTCC
CTTCTGAAGCACAACCCACCCACGCACAGTCATCCAAGCCCCAAGTTGCAGCACAGTCTCAGCCTCAAAGTAATGTCCAAGGACAGTCTC
CTGTTCGTGTCCAAAGTCCATCACAGACTCGAATACGTCCATCAACTCCATCCCAACTGTCTCCTGGACAACAATCCCAGGTTCAGACTA
CAACCTCACAACCGATTCCAATTCAACCACATACATCTCTTCAGATACCTTCCCAAGGCCAGCCACAGTCACAACCCCAGGTACAGTCTT
CAACTCAAACTCTTTCATCAGGACAAACTTTAAATCAAGTTACTGTTTCATCCCCATCCCGTCCTCAGCTACAAATACAGCAGCCACAGC
CCCAAGTCATTGCTGTGCCTCAGCTGCAACAACAAGTCCAGGTTCTCTCTCAGATCCAGTCACAGGTTGTGGCTCAGATACAGGCTCAGC
AAAGTGGTGTGCCCCAGCAAATCAAACTCCAGTTACCTATCCAAATTCAGCAAAGCAGTGCTGTGCAGACTCACCAGATTCAGAATGTGG
TTACAGTGCAGGCAGCCAGTGTGCAAGAGCAGTTGCAAAGGGTTCAGCAACTCAGGGATCAGCAGCAAAAGAAGAAACAGCAACAGATAG
AAATTAAGCGTGAACACACCCTCCAAGCTTCTAATCAAAGTGAAATCATTCAGAAACAGGTGGTGATGAAGCATAATGCTGTAATAGAAC
ATTTAAAACAGAAAAAGAGCATGACTCCAGCTGAAAGAGAAGAGAATCAAAGAATGATTGTCTGTAACCAGGTGATGAAGTATATTTTGG
ATAAGATAGATAAAGAAGAAAAACAGGCAGCAAAAAAACGGAAGCGTGAAGAGAGTGTGGAGCAGAAACGTAGCAAGCAGAATGCCACTA
AGCTGTCAGCTCTGCTCTTCAAGCACAAAGAGCAGCTCAGAGCCGAGATCCTGAAGAAGAGAGCACTCCTGGACAAGGATCTGCAAATTG
AAGTGCAGGAAGAGCTGAAGAGAGACCTGAAAATTAAGAAAGAAAAAGACCTGATGCAGTTGGCTCAGGCCACAGCAGTAGCTGCACCCT
GCCCCCCAGTGACACCAGCTCCTCCAGCCCCTCCAGCCCCTCCACCTTCACCTCCCCCTCCACCTGCTGTGCAACACACAGGCCTTCTGT
CCACGCCCACCTTACCTGCTGCTTCCCAGAAGAGGAAGCGGGAAGAGGAAAAAGACTCCAGCTCAAAGTCCAAGAAAAAGAAAATGATCT
CTACTACCTCAAAGGAAACTAAGAAGGACACAAAGCTTTACTGTATCTGTAAAACGCCTTATGATGAATCTAAATTTTATATTGGCTGTG
ATCGGTGTCAGAATTGGTACCATGGGCGCTGCGTTGGCATCTTGCAAAGTGAGGCAGAGCTCATTGATGAGTATGTCTGTCCACAGTGCC
AGTCAACAGAGGATGCCATGACAGTGCTCACGCCACTAACAGAGAAGGATTATGAGGGGTTGAAGAGGGTGCTCCGTTCCTTACAGGCCC
ATAAGATGGCCTGGCCTTTCCTTGAACCAGTAGACCCTAATGATGCACCAGATTATTATGGTGTTATTAAGGAACCTATGGACCTTGCCA
CCATGGAAGAAAGAGTACAAAGACGATATTATGAAAAGCTGACGGAATTTGTGGCAGATATGACCAAAATTTTTGATAACTGTCGTTACT
ACAATCCAAGTGACTCCCCATTTTACCAGTGTGCAGAAGTTCTCGAATCATTCTTTGTACAGAAATTGAAAGGCTTCAAAGCTAGCAGGT
CTCATAACAACAAACTGCAGTCTACAGCTTCTTAAAGTTCAGCGTGTTAACCTAACATAAAACACAGCAAGAATCTGGTTGTCTGAACTA
TTTTAAATTAAGGAGCCAGATGTTTTTAGTCAGGCTATCCTGACAAGACTTGACCTAAACTTCGTTTTTATTGGTCATAACAGTCCAATT
ATATTCTTGGCCAATTTTGTCCAACGGACAAGAAAAAAGCAAAGTCAACGACACCATTATCTTGTCAAGATCAGATGGTTTTACTATTGT
GGCAGAAGCGAGAAAACTTTGTTTATTGAAAAAAAAAGAAAAAGAAAGCAAGAAAAAAAGATACTATGGGGTCAAGTGTAACTCCATGGA
AATGCCACGTCTGCTCTTCAGTGAAGAAGCTGGTTTAGAGTCTCACAGAAAACTTTTGACTGTATTTATTTATTGTTGCAAAAAAGACGC
TTTTTTATTGCTGCCCTCATTTGTCAGCTAATTATTTTTTCTTATAAAATCCAGCCCCGGTTACATATAATCATCTGTATCTTATCATGA
TTCCTGTAGGTAAAAGTACAAGACGACCTCTAGATGTCTTTTCTTTCTATGAAAGGAGCTGCTATGTACACATGTGCACACACACACAAC
TGGGAATCAACAATGAGTTTATTGTTCATGGTAGATTAAAATTAAGCTTGCATAAAGGTTGGGCTAAGTGGTCCTGGACTACAGACTCTG
TTGCCTTGAATATAACAGTACAATTTGTCAATTACTCTGCACCAGGCTAAAATGAGTAAAATCTATTTGAAGGTATCTTGTTTGTAAACA
TTTGTCAGATTCTAATTTTTTTCTTTTGTATTAAAATTCAACTATGGATGTATATGAAACAAAATAAATGGAGATAATTTTTCTCCCACA

>64664_64664_13_PGS1-BPTF_PGS1_chr17_76400170_ENST00000329897_BPTF_chr17_65916131_ENST00000306378_length(amino acids)=1533AA_BP=422
MRRDPCSGGDCWASCLAAQGWPRSWDACPTASAGTGTASAGAVPQVTSPPCCLCPEGVHRFQWIRNLVPEFGVSSSHVRVLSSPAEFFEL
MKVDCLESTLEKSLQAKFPSNLKVSILLDFTRGSRGRKNSRTMLLPLLRRFPEQVRVSLFHTPHLRGLLRLLIPERFNETIGLQHIKVYL
FDNSVILSGANLSDSYFTNRQDRYVFLQDCAEIADFFTELVDAVGDVSLQLQGDDTVQVVDGMVHPYKGDRAEYCKAANKRVMDVINSAR
TRQQMLHAQTFHSNSLLTQEDAAAAGDRRPAPDTWIYPLIQMKPFEIQIDEIVTETLLTEAERGAKVYLTTGYFNLTQAYMDLVLGTRAE
YQILLASPEVNGFFGAKGVAGAIPAAYVHIERQFFSEVCSLGQQERVQLQEYWRRGWTFHAKETSETEITTTEIIKRRDVGPYGIRSEYC
IRKIICPIGVPETPKETPTPQRKGLRSSALRPKRPETPKQTGPVIIETWVAEEELELWEIRAFAERVEKEKAQAVEQQAKKRLEQQKPTV
IATSTTSPTSSTTSTISPAQKVMVAPISGSVTTGTKMVLTTKVGSPATVTFQQNKNFHQTFATWVKQGQSNSGVVQVQQKVLGIIPSSTG
TSQQTFTSFQPRTATVTIRPNTSGSGGTTSNSQVITGPQIRPGMTVIRTPLQQSTLGKAIIRTPVMVQPGAPQQVMTQIIRGQPVSTAVS
APNTVSSTPGQKSLTSATSTSNIQSSASQPPRPQQGQVKLTMAQLTQLTQGHGGNQGLTVVIQGQGQTTGQLQLIPQGVTVLPGPGQQLM
QAAMPNGTVQRFLFTPLATTATTASTTTTTVSTTAAGTGEQRQSKLSPQMQVHQDKTLPPAQSSSVGPAEAQPQTAQPSAQPQPQTQPQS
PAQPEVQTQPEVQTQTTVSSHVPSEAQPTHAQSSKPQVAAQSQPQSNVQGQSPVRVQSPSQTRIRPSTPSQLSPGQQSQVQTTTSQPIPI
QPHTSLQIPSQGQPQSQPQVQSSTQTLSSGQTLNQVTVSSPSRPQLQIQQPQPQVIAVPQLQQQVQVLSQIQSQVVAQIQAQQSGVPQQI
KLQLPIQIQQSSAVQTHQIQNVVTVQAASVQEQLQRVQQLRDQQQKKKQQQIEIKREHTLQASNQSEIIQKQVVMKHNAVIEHLKQKKSM
TPAEREENQRMIVCNQVMKYILDKIDKEEKQAAKKRKREESVEQKRSKQNATKLSALLFKHKEQLRAEILKKRALLDKDLQIEVQEELKR
DLKIKKEKDLMQLAQATAVAAPCPPVTPAPPAPPAPPPSPPPPPAVQHTGLLSTPTLPAASQKRKREEEKDSSSKSKKKKMISTTSKETK
KDTKLYCICKTPYDESKFYIGCDRCQNWYHGRCVGILQSEAELIDEYVCPQCQSTEDAMTVLTPLTEKDYEGLKRVLRSLQAHKMAWPFL
EPVDPNDAPDYYGVIKEPMDLATMEERVQRRYYEKLTEFVADMTKIFDNCRYYNPSDSPFYQCAEVLESFFVQKLKGFKASRSHNNKLQS

--------------------------------------------------------------
>64664_64664_14_PGS1-BPTF_PGS1_chr17_76400170_ENST00000329897_BPTF_chr17_65916131_ENST00000321892_length(transcript)=6715nt_BP=1290nt
CTCCATGGCGGTGGCGGCGGCAGCTGCGGCGGGACCCGTGTTCTGGAGGCGACTGCTGGGCCTCCTGCCTGGCCGCCCAGGGCTGGCCGC
GCTCCTGGGACGCCTGTCCGACCGCCTCGGCAGGAACCGGGACCGCCAGCGCAGGAGCTGTTCCCCAGGTCACCTCCCCACCTTGCTGCC
TGTGTCCAGAAGGCGTGCACCGGTTCCAGTGGATCAGAAACCTGGTTCCAGAATTTGGAGTCTCCAGTTCTCACGTTAGGGTGCTTTCTT
CCCCGGCAGAGTTTTTCGAGCTCATGAAGGTGGACTGCCTGGAAAGTACTCTAGAAAAGTCACTCCAAGCAAAGTTTCCTTCAAATCTCA
AGGTCTCCATTCTCTTAGACTTCACGCGGGGCTCACGAGGCCGGAAGAACTCCCGCACAATGCTGCTCCCACTCCTGCGGAGGTTCCCAG
AGCAGGTCCGAGTCTCCCTCTTTCACACGCCGCACCTCCGTGGGCTGCTTCGGCTCCTCATCCCTGAGCGCTTCAACGAGACCATCGGCC
TCCAGCACATTAAGGTGTACCTCTTCGACAACAGCGTCATCTTGAGCGGTGCAAACCTGAGTGACTCCTACTTCACCAACCGCCAGGACC
GCTACGTGTTCCTGCAGGACTGTGCGGAGATTGCCGACTTCTTCACGGAGCTGGTGGACGCGGTGGGGGATGTGTCCCTGCAGCTGCAGG
GGGACGACACGGTGCAGGTGGTGGATGGGATGGTGCATCCTTACAAAGGGGACCGGGCCGAGTACTGCAAGGCAGCCAATAAGAGGGTCA
TGGATGTGATCAACTCAGCCAGGACCCGCCAGCAGATGCTGCATGCCCAGACCTTCCACAGCAACTCTCTTTTGACCCAGGAAGATGCAG
CAGCTGCTGGGGATCGCAGACCAGCCCCTGACACCTGGATTTATCCGCTGATTCAGATGAAGCCCTTCGAGATTCAAATCGATGAGATTG
TCACTGAGACCCTGTTGACTGAGGCGGAGCGCGGGGCAAAGGTCTACCTCACCACTGGCTATTTCAACCTGACCCAGGCCTACATGGACC
TGGTCTTGGGCACTCGGGCTGAGTACCAGATCCTGCTGGCCTCACCAGAGGTGAATGGCTTCTTTGGGGCCAAGGGGGTGGCCGGCGCCA
TCCCAGCGGCCTATGTGCACATCGAGCGACAGTTCTTCAGTGAGGTGTGCAGCCTGGGACAGCAGGAGCGGGTCCAGCTTCAGGAGTACT
GGCGGAGGGGCTGGACGTTCCACGCCAAAGAAACATCCGAAACTGAAATCACAACAACAGAAATAATTAAGAGGAGAGATGTTGGTCCTT
ATGGCATTCGATCTGAATATTGTATCAGGAAAATCATTTGTCCCATTGGAGTTCCAGAAACACCAAAAGAAACGCCTACACCTCAGAGGA
AAGGCCTTCGATCAAGTGCACTGCGGCCAAAGAGACCAGAAACGCCCAAGCAAACTGGCCCTGTTATTATTGAAACCTGGGTAGCAGAAG
AAGAACTGGAATTGTGGGAGATCAGGGCATTTGCTGAGAGAGTGGAGAAAGAAAAGGCACAAGCAGTTGAGCAACAGGCTAAGAAACGAC
TGGAGCAGCAGAAGCCGACAGTGATTGCAACTTCCACTACTTCCCCAACAAGCAGTACAACCAGCACCATCTCTCCAGCACAGAAGGTTA
TGGTGGCCCCCATAAGTGGCTCAGTTACAACTGGAACCAAAATGGTACTAACTACTAAAGTTGGATCTCCAGCTACAGTAACATTCCAAC
AAAACAAGAACTTTCATCAAACCTTTGCTACATGGGTTAAGCAAGGCCAGTCAAATTCAGGCGTTGTTCAAGTACAGCAGAAAGTCCTGG
GTATCATTCCATCAAGTACAGGTACCAGTCAGCAAACCTTTACTTCATTCCAGCCCAGGACAGCAACAGTCACAATTAGGCCCAATACCT
CAGGCTCTGGAGGAACCACAAGCAATTCACAAGTAATCACAGGGCCTCAGATTCGCCCTGGTATGACCGTGATTAGAACACCACTCCAAC
AGTCAACACTAGGAAAGGCAATTATTCGAACACCTGTGATGGTACAGCCAGGTGCTCCTCAGCAAGTGATGACTCAAATCATCAGGGGGC
AGCCTGTCTCCACTGCAGTCTCCGCCCCTAACACGGTTTCCTCAACACCTGGGCAGAAAAGCTTAACTTCAGCAACGTCCACTTCAAATA
TACAGTCTTCAGCCTCACAACCCCCTCGCCCCCAACAAGGACAAGTGAAGCTCACCATGGCTCAACTTACTCAGTTAACACAGGGCCACG
GTGGCAATCAAGGTTTGACAGTAGTAATTCAAGGACAAGGTCAAACTACTGGACAGTTGCAGTTGATACCTCAAGGGGTGACTGTACTCC
CAGGCCCAGGCCAGCAGCTAATGCAAGCTGCAATGCCAAATGGTACTGTTCAGCGATTCCTCTTTACCCCATTGGCAACAACAGCCACCA
CAGCCAGCACCACCACCACCACTGTTTCCACGACAGCAGCAGGTACAGGTGAACAAAGGCAGAGTAAACTGTCACCCCAGATGCAGGTAC
ATCAAGACAAAACCCTGCCACCAGCTCAGTCATCAAGTGTGGGTCCAGCAGAAGCCCAGCCACAGACTGCTCAGCCTTCAGCTCAGCCCC
AGCCCCAAACCCAGCCCCAGTCCCCAGCTCAGCCTGAAGTTCAGACTCAGCCTGAAGTTCAGACCCAAACAACTGTTTCATCCCATGTCC
CTTCTGAAGCACAACCCACCCACGCACAGTCATCCAAGCCCCAAGTTGCAGCACAGTCTCAGCCTCAAAGTAATGTCCAAGGACAGTCTC
CTGTTCGTGTCCAAAGTCCATCACAGACTCGAATACGTCCATCAACTCCATCCCAACTGTCTCCTGGACAACAATCCCAGGTTCAGACTA
CAACCTCACAACCGATTCCAATTCAACCACATACATCTCTTCAGATACCTTCCCAAGGCCAGCCACAGTCACAACCCCAGGTACAGTCTT
CAACTCAAACTCTTTCATCAGGACAAACTTTAAATCAAGTTACTGTTTCATCCCCATCCCGTCCTCAGCTACAAATACAGCAGCCACAGC
CCCAAGTCATTGCTGTGCCTCAGCTGCAACAACAAGTCCAGGTTCTCTCTCAGATCCAGTCACAGGTTGTGGCTCAGATACAGGCTCAGC
AAAGTGGTGTGCCCCAGCAAATCAAACTCCAGTTACCTATCCAAATTCAGCAAAGCAGTGCTGTGCAGACTCACCAGATTCAGAATGTGG
TTACAGTGCAGGCAGCCAGTGTGCAAGAGCAGTTGCAAAGGGTTCAGCAACTCAGGGATCAGCAGCAAAAGAAGAAACAGCAACAGATAG
AAATTAAGCGTGAACACACCCTCCAAGCTTCTAATCAAAGTGAAATCATTCAGAAACAGGTGGTGATGAAGCATAATGCTGTAATAGAAC
ATTTAAAACAGAAAAAGAGCATGACTCCAGCTGAAAGAGAAGAGAATCAAAGAATGATTGTCTGTAACCAGGTGATGAAGTATATTTTGG
ATAAGATAGATAAAGAAGAAAAACAGGCAGCAAAAAAACGGAAGCGTGAAGAGAGTGTGGAGCAGAAACGTAGCAAGCAGAATGCCACTA
AGCTGTCAGCTCTGCTCTTCAAGCACAAAGAGCAGCTCAGAGCCGAGATCCTGAAGAAGAGAGCACTCCTGGACAAGGATCTGCAAATTG
AAGTGCAGGAAGAGCTGAAGAGAGACCTGAAAATTAAGAAAGAAAAAGACCTGATGCAGTTGGCTCAGGCCACAGCAGTAGCTGCACCCT
GCCCCCCAGTGACACCAGCTCCTCCAGCCCCTCCAGCCCCTCCACCTTCACCTCCCCCTCCACCTGCTGTGCAACACACAGGCCTTCTGT
CCACGCCCACCTTACCTGCTGCTTCCCAGAAGAGGAAGCGGGAAGAGGAAAAAGACTCCAGCTCAAAGTCCAAGAAAAAGAAAATGATCT
CTACTACCTCAAAGGAAACTAAGAAGGACACAAAGCTTTACTGTATCTGTAAAACGCCTTATGATGAATCTAAATTTTATATTGGCTGTG
ATCGGTGTCAGAATTGGTACCATGGGCGCTGCGTTGGCATCTTGCAAAGTGAGGCAGAGCTCATTGATGAGTATGTCTGTCCACAGTGCC
AGTCAACAGAGGATGCCATGACAGTGCTCACGCCACTAACAGAGAAGGATTATGAGGGGTTGAAGAGGGTGCTCCGTTCCTTACAGGCCC
ATAAGATGGCCTGGCCTTTCCTTGAACCAGTAGACCCTAATGATGCACCAGATTATTATGGTGTTATTAAGGAACCTATGGACCTTGCCA
CCATGGAAGAAAGAGTACAAAGACGATATTATGAAAAGCTGACGGAATTTGTGGCAGATATGACCAAAATTTTTGATAACTGTCGTTACT
ACAATCCAAGTGACTCCCCATTTTACCAGTGTGCAGAAGTTCTCGAATCATTCTTTGTACAGAAATTGAAAGGCTTCAAAGCTAGCAGGT
CTCATAACAACAAACTGCAGTCTACAGCTTCTTAAAGTTCAGCGTGTTAACCTAACATAAAACACAGCAAGAATCTGGTTGTCTGAACTA
TTTTAAATTAAGGAGCCAGATGTTTTTAGTCAGGCTATCCTGACAAGACTTGACCTAAACTTCGTTTTTATTGGTCATAACAGTCCAATT
ATATTCTTGGCCAATTTTGTCCAACGGACAAGAAAAAAGCAAAGTCAACGACACCATTATCTTGTCAAGATCAGATGGTTTTACTATTGT
GGCAGAAGCGAGAAAACTTTGTTTATTGAAAAAAAAAGAAAAAGAAAGCAAGAAAAAAAGATACTATGGGGTCAAGTGTAACTCCATGGA
AATGCCACGTCTGCTCTTCAGTGAAGAAGCTGGTTTAGAGTCTCACAGAAAACTTTTGACTGTATTTATTTATTGTTGCAAAAAAGACGC
TTTTTTATTGCTGCCCTCATTTGTCAGCTAATTATTTTTTCTTATAAAATCCAGCCCCGGTTACATATAATCATCTGTATCTTATCATGA
TTCCTGTAGGTAAAAGTACAAGACGACCTCTAGATGTCTTTTCTTTCTATGAAAGGAGCTGCTATGTACACATGTGCACACACACACAAC
TGGGAATCAACAATGAGTTTATTGTTCATGGTAGATTAAAATTAAGCTTGCATAAAGGTTGGGCTAAGTGGTCCTGGACTACAGACTCTG
TTGCCTTGAATATAACAGTACAATTTGTCAATTACTCTGCACCAGGCTAAAATGAGTAAAATCTATTTGAAGGTATCTTGTTTGTAAACA
TTTGTCAGATTCTAATTTTTTTCTTTTGTATTAAAATTCAACTATGGATGTATATGAAACAAAATAAATGGAGATAATTTTTCTCCCACA
GACAGAGGTGTCTTTGAATGTGCGCTAATGATTATCTGTAAGCCTTTGTGGGGAGGGAGGCCTGCAAGGTCATGAAAGGCAGAAGAGTCT
AATTGTGCCTGGATTTCTCCAGGACAGCAGTGGCCCCTCGTTTTATCATTCCCAGTCCATTGTCATCACGTCAGAGAAAAATCTTCAGGG
GTGCTAATCCTGTTGCATCAGTTGATCATACTAACGAGAACGGTAATGCGACAAGATACACATTGCCTTCATCTGTACATTCTGTGATAC
CAGGCAAATTACCAATTACACACAGCTACTTATATTTTATGAAGGGCATTTTTTAGATGACCTCATCCTCTGTGTTATTTGTTGATTGGG
TTTGTTTTCTGTTTGTTGGTTTGTTTGTTTCTTCCACGTAAGGAAAAGTAGTGTAAACAGTAGCGAGAAAATGGAAACCACAGAGGAAGA
TGTATTTTGCATGTTTTTCCTTTCAGTGTTCTTACACGTTGTATCACTGCATTGTGGTAATAGCTTCTATAAAATCTGCCATAGTTGGAT
TATGCAGCTTTGCAAAAATTTTTACTAGATTTTGCACTAACTCATATTAGCTTTGTCCTACCAACTTCTGGAATTTATCTAATTATTGTT
TTTCAAAGTTTCTTTCCTTTTAATGTTTCCCTGCTATGCAAAACCTTTCCCAGACCTCAGTTTCTTAAAAGAAAGATGTTGCTACAGTTC
CCGATTCTTTCTTATTACAGGCTCAGGTGTACAGGTTATTCTGGGTTAATTTTATCTAATGAAGCCCATTCCTTTTTGTACATAAAGATG
TCACTTAAACTTATGCTTACAAACTAAAGACTAATCGCTCAATATGAAAACATGAAAAAATTTTTGCTTAAAGTATTAAGATGGAAGTAG
TTAAATATGGGTTATTTTGTCCTTTTACTTTTTTAAAAAATGTTACATATTGTATGCACTGTGCTGATGCAAGAATTCTACATTTTAATG
AGTTATAAAATTATTCTGCATCTCATCACGTCACAGTATTTCTGTACTATTTATTCATATATATAAATATATATGGGCTTAATCATTTAA
AATTTGTTGCAGCAAGAACTTTCCTACCTGTAGGCAATAGATTGCTATGTTTTTAACAAATTGTGGCAAATTCTAAACAGCAATTCTTTT

>64664_64664_14_PGS1-BPTF_PGS1_chr17_76400170_ENST00000329897_BPTF_chr17_65916131_ENST00000321892_length(amino acids)=1533AA_BP=422
MRRDPCSGGDCWASCLAAQGWPRSWDACPTASAGTGTASAGAVPQVTSPPCCLCPEGVHRFQWIRNLVPEFGVSSSHVRVLSSPAEFFEL
MKVDCLESTLEKSLQAKFPSNLKVSILLDFTRGSRGRKNSRTMLLPLLRRFPEQVRVSLFHTPHLRGLLRLLIPERFNETIGLQHIKVYL
FDNSVILSGANLSDSYFTNRQDRYVFLQDCAEIADFFTELVDAVGDVSLQLQGDDTVQVVDGMVHPYKGDRAEYCKAANKRVMDVINSAR
TRQQMLHAQTFHSNSLLTQEDAAAAGDRRPAPDTWIYPLIQMKPFEIQIDEIVTETLLTEAERGAKVYLTTGYFNLTQAYMDLVLGTRAE
YQILLASPEVNGFFGAKGVAGAIPAAYVHIERQFFSEVCSLGQQERVQLQEYWRRGWTFHAKETSETEITTTEIIKRRDVGPYGIRSEYC
IRKIICPIGVPETPKETPTPQRKGLRSSALRPKRPETPKQTGPVIIETWVAEEELELWEIRAFAERVEKEKAQAVEQQAKKRLEQQKPTV
IATSTTSPTSSTTSTISPAQKVMVAPISGSVTTGTKMVLTTKVGSPATVTFQQNKNFHQTFATWVKQGQSNSGVVQVQQKVLGIIPSSTG
TSQQTFTSFQPRTATVTIRPNTSGSGGTTSNSQVITGPQIRPGMTVIRTPLQQSTLGKAIIRTPVMVQPGAPQQVMTQIIRGQPVSTAVS
APNTVSSTPGQKSLTSATSTSNIQSSASQPPRPQQGQVKLTMAQLTQLTQGHGGNQGLTVVIQGQGQTTGQLQLIPQGVTVLPGPGQQLM
QAAMPNGTVQRFLFTPLATTATTASTTTTTVSTTAAGTGEQRQSKLSPQMQVHQDKTLPPAQSSSVGPAEAQPQTAQPSAQPQPQTQPQS
PAQPEVQTQPEVQTQTTVSSHVPSEAQPTHAQSSKPQVAAQSQPQSNVQGQSPVRVQSPSQTRIRPSTPSQLSPGQQSQVQTTTSQPIPI
QPHTSLQIPSQGQPQSQPQVQSSTQTLSSGQTLNQVTVSSPSRPQLQIQQPQPQVIAVPQLQQQVQVLSQIQSQVVAQIQAQQSGVPQQI
KLQLPIQIQQSSAVQTHQIQNVVTVQAASVQEQLQRVQQLRDQQQKKKQQQIEIKREHTLQASNQSEIIQKQVVMKHNAVIEHLKQKKSM
TPAEREENQRMIVCNQVMKYILDKIDKEEKQAAKKRKREESVEQKRSKQNATKLSALLFKHKEQLRAEILKKRALLDKDLQIEVQEELKR
DLKIKKEKDLMQLAQATAVAAPCPPVTPAPPAPPAPPPSPPPPPAVQHTGLLSTPTLPAASQKRKREEEKDSSSKSKKKKMISTTSKETK
KDTKLYCICKTPYDESKFYIGCDRCQNWYHGRCVGILQSEAELIDEYVCPQCQSTEDAMTVLTPLTEKDYEGLKRVLRSLQAHKMAWPFL
EPVDPNDAPDYYGVIKEPMDLATMEERVQRRYYEKLTEFVADMTKIFDNCRYYNPSDSPFYQCAEVLESFFVQKLKGFKASRSHNNKLQS

--------------------------------------------------------------
>64664_64664_15_PGS1-BPTF_PGS1_chr17_76400170_ENST00000329897_BPTF_chr17_65916131_ENST00000335221_length(transcript)=6286nt_BP=1290nt
CTCCATGGCGGTGGCGGCGGCAGCTGCGGCGGGACCCGTGTTCTGGAGGCGACTGCTGGGCCTCCTGCCTGGCCGCCCAGGGCTGGCCGC
GCTCCTGGGACGCCTGTCCGACCGCCTCGGCAGGAACCGGGACCGCCAGCGCAGGAGCTGTTCCCCAGGTCACCTCCCCACCTTGCTGCC
TGTGTCCAGAAGGCGTGCACCGGTTCCAGTGGATCAGAAACCTGGTTCCAGAATTTGGAGTCTCCAGTTCTCACGTTAGGGTGCTTTCTT
CCCCGGCAGAGTTTTTCGAGCTCATGAAGGTGGACTGCCTGGAAAGTACTCTAGAAAAGTCACTCCAAGCAAAGTTTCCTTCAAATCTCA
AGGTCTCCATTCTCTTAGACTTCACGCGGGGCTCACGAGGCCGGAAGAACTCCCGCACAATGCTGCTCCCACTCCTGCGGAGGTTCCCAG
AGCAGGTCCGAGTCTCCCTCTTTCACACGCCGCACCTCCGTGGGCTGCTTCGGCTCCTCATCCCTGAGCGCTTCAACGAGACCATCGGCC
TCCAGCACATTAAGGTGTACCTCTTCGACAACAGCGTCATCTTGAGCGGTGCAAACCTGAGTGACTCCTACTTCACCAACCGCCAGGACC
GCTACGTGTTCCTGCAGGACTGTGCGGAGATTGCCGACTTCTTCACGGAGCTGGTGGACGCGGTGGGGGATGTGTCCCTGCAGCTGCAGG
GGGACGACACGGTGCAGGTGGTGGATGGGATGGTGCATCCTTACAAAGGGGACCGGGCCGAGTACTGCAAGGCAGCCAATAAGAGGGTCA
TGGATGTGATCAACTCAGCCAGGACCCGCCAGCAGATGCTGCATGCCCAGACCTTCCACAGCAACTCTCTTTTGACCCAGGAAGATGCAG
CAGCTGCTGGGGATCGCAGACCAGCCCCTGACACCTGGATTTATCCGCTGATTCAGATGAAGCCCTTCGAGATTCAAATCGATGAGATTG
TCACTGAGACCCTGTTGACTGAGGCGGAGCGCGGGGCAAAGGTCTACCTCACCACTGGCTATTTCAACCTGACCCAGGCCTACATGGACC
TGGTCTTGGGCACTCGGGCTGAGTACCAGATCCTGCTGGCCTCACCAGAGGTGAATGGCTTCTTTGGGGCCAAGGGGGTGGCCGGCGCCA
TCCCAGCGGCCTATGTGCACATCGAGCGACAGTTCTTCAGTGAGGTGTGCAGCCTGGGACAGCAGGAGCGGGTCCAGCTTCAGGAGTACT
GGCGGAGGGGCTGGACGTTCCACGCCAAAGAAACATCCGAAACTGAAATCACAACAACAGAAATAATTAAGAGGAGAGATGTTGGTCCTT
ATGGCATTCGATCTGAATATTGTATCAGGAAAATCATTTGTCCCATTGGAGTTCCAGAAACACCAAAAGAAACGCCTACACCTCAGAGGA
AAGGCCTTCGATCAAGTGCACTGCGGCCAAAGAGACCAGAAACGCCCAAGCAAACTGGCCCTGTTATTATTGAAACCTGGGTAGCAGAAG
AAGAACTGGAATTGTGGGAGATCAGGGCATTTGCTGAGAGAGTGGAGAAAGAAAAGGCACAAGCAGTTGAGCAACAGGCTAAGAAACGAC
TGGAGCAGCAGAAGCCGACAGTGATTGCAACTTCCACTACTTCCCCAACAAGCAGTACAACCAGCACCATCTCTCCAGCACAGAAGGTTA
TGGTGGCCCCCATAAGTGGCTCAGTTACAACTGGAACCAAAATGGTACTAACTACTAAAGTTGGATCTCCAGCTACAGTAACATTCCAAC
AAAACAAGAACTTTCATCAAACCTTTGCTACATGGGTTAAGCAAGGCCAGTCAAATTCAGGCGTTGTTCAAGTACAGCAGAAAGTCCTGG
GTATCATTCCATCAAGTACAGGTACCAGTCAGCAAACCTTTACTTCATTCCAGCCCAGGACAGCAACAGTCACAATTAGGCCCAATACCT
CAGGCTCTGGAGGAACCACAAGCAATTCACAAGTAATCACAGGGCCTCAGATTCGCCCTGGTATGACCGTGATTAGAACACCACTCCAAC
AGTCAACACTAGGAAAGGCAATTATTCGAACACCTGTGATGGTACAGCCAGGTGCTCCTCAGCAAGTGATGACTCAAATCATCAGGGGGC
AGCCTGTCTCCACTGCAGTCTCCGCCCCTAACACGGTTTCCTCAACACCTGGGCAGAAAAGCTTAACTTCAGCAACGTCCACTTCAAATA
TACAGTCTTCAGCCTCACAACCCCCTCGCCCCCAACAAGGACAAGTGAAGCTCACCATGGCTCAACTTACTCAGTTAACACAGGGCCACG
GTGGCAATCAAGGTTTGACAGTAGTAATTCAAGGACAAGGTCAAACTACTGGACAGTTGCAGTTGATACCTCAAGGGGTGACTGTACTCC
CAGGCCCAGGCCAGCAGCTAATGCAAGCTGCAATGCCAAATGGTACTGTTCAGCGATTCCTCTTTACCCCATTGGCAACAACAGCCACCA
CAGCCAGCACCACCACCACCACTGTTTCCACGACAGCAGCAGGTACAGGTGAACAAAGGCAGAGTAAACTGTCACCCCAGATGCAGGTAC
ATCAAGACAAAACCCTGCCACCAGCTCAGTCATCAAGTGTGGGTCCAGCAGAAGCCCAGCCACAGACTGCTCAGCCTTCAGCTCAGCCCC
AGCCCCAAACCCAGCCCCAGTCCCCAGCTCAGCCTGAAGTTCAGACTCAGCCTGAAGTTCAGACCCAAACAACTGTTTCATCCCATGTCC
CTTCTGAAGCACAACCCACCCACGCACAGTCATCCAAGCCCCAAGTTGCAGCACAGTCTCAGCCTCAAAGTAATGTCCAAGGACAGTCTC
CTGTTCGTGTCCAAAGTCCATCACAGACTCGAATACGTCCATCAACTCCATCCCAACTGTCTCCTGGACAACAATCCCAGGTTCAGACTA
CAACCTCACAACCGATTCCAATTCAACCACATACATCTCTTCAGATACCTTCCCAAGGCCAGCCACAGTCACAACCCCAGGTGGTGATGA
AGCATAATGCTGTAATAGAACATTTAAAACAGAAAAAGAGCATGACTCCAGCTGAAAGAGAAGAGAATCAAAGAATGATTGTCTGTAACC
AGGTGATGAAGTATATTTTGGATAAGATAGATAAAGAAGAAAAACAGGCAGCAAAAAAACGGAAGCGTGAAGAGAGTGTGGAGCAGAAAC
GTAGCAAGCAGAATGCCACTAAGCTGTCAGCTCTGCTCTTCAAGCACAAAGAGCAGCTCAGAGCCGAGATCCTGAAGAAGAGAGCACTCC
TGGACAAGGATCTGCAAATTGAAGTGCAGGAAGAGCTGAAGAGAGACCTGAAAATTAAGAAAGAAAAAGACCTGATGCAGTTGGCTCAGG
CCACAGCAGTAGCTGCACCCTGCCCCCCAGTGACACCAGCTCCTCCAGCCCCTCCAGCCCCTCCACCTTCACCTCCCCCTCCACCTGCTG
TGCAACACACAGGCCTTCTGTCCACGCCCACCTTACCTGCTGCTTCCCAGAAGAGGAAGCGGGAAGAGGAAAAAGACTCCAGCTCAAAGT
CCAAGAAAAAGAAAATGATCTCTACTACCTCAAAGGAAACTAAGAAGGACACAAAGCTTTACTGTATCTGTAAAACGCCTTATGATGAAT
CTAAATTTTATATTGGCTGTGATCGGTGTCAGAATTGGTACCATGGGCGCTGCGTTGGCATCTTGCAAAGTGAGGCAGAGCTCATTGATG
AGTATGTCTGTCCACAGTGCCAGTCAACAGAGGATGCCATGACAGTGCTCACGCCACTAACAGAGAAGGATTATGAGGGGTTGAAGAGGG
TGCTCCGTTCCTTACAGGCCCATAAGATGGCCTGGCCTTTCCTTGAACCAGTAGACCCTAATGATGCACCAGATTATTATGGTGTTATTA
AGGAACCTATGGACCTTGCCACCATGGAAGAAAGAGTACAAAGACGATATTATGAAAAGCTGACGGAATTTGTGGCAGATATGACCAAAA
TTTTTGATAACTGTCGTTACTACAATCCAAGTGACTCCCCATTTTACCAGTGTGCAGAAGTTCTCGAATCATTCTTTGTACAGAAATTGA
AAGGCTTCAAAGCTAGCAGGTCTCATAACAACAAACTGCAGTCTACAGCTTCTTAAAGTTCAGCGTGTTAACCTAACATAAAACACAGCA
AGAATCTGGTTGTCTGAACTATTTTAAATTAAGGAGCCAGATGTTTTTAGTCAGGCTATCCTGACAAGACTTGACCTAAACTTCGTTTTT
ATTGGTCATAACAGTCCAATTATATTCTTGGCCAATTTTGTCCAACGGACAAGAAAAAAGCAAAGTCAACGACACCATTATCTTGTCAAG
ATCAGATGGTTTTACTATTGTGGCAGAAGCGAGAAAACTTTGTTTATTGAAAAAAAAAGAAAAAGAAAGCAAGAAAAAAAGATACTATGG
GGTCAAGTGTAACTCCATGGAAATGCCACGTCTGCTCTTCAGTGAAGAAGCTGGTTTAGAGTCTCACAGAAAACTTTTGACTGTATTTAT
TTATTGTTGCAAAAAAGACGCTTTTTTATTGCTGCCCTCATTTGTCAGCTAATTATTTTTTCTTATAAAATCCAGCCCCGGTTACATATA
ATCATCTGTATCTTATCATGATTCCTGTAGGTAAAAGTACAAGACGACCTCTAGATGTCTTTTCTTTCTATGAAAGGAGCTGCTATGTAC
ACATGTGCACACACACACAACTGGGAATCAACAATGAGTTTATTGTTCATGGTAGATTAAAATTAAGCTTGCATAAAGGTTGGGCTAAGT
GGTCCTGGACTACAGACTCTGTTGCCTTGAATATAACAGTACAATTTGTCAATTACTCTGCACCAGGCTAAAATGAGTAAAATCTATTTG
AAGGTATCTTGTTTGTAAACATTTGTCAGATTCTAATTTTTTTCTTTTGTATTAAAATTCAACTATGGATGTATATGAAACAAAATAAAT
GGAGATAATTTTTCTCCCACAGACAGAGGTGTCTTTGAATGTGCGCTAATGATTATCTGTAAGCCTTTGTGGGGAGGGAGGCCTGCAAGG
TCATGAAAGGCAGAAGAGTCTAATTGTGCCTGGATTTCTCCAGGACAGCAGTGGCCCCTCGTTTTATCATTCCCAGTCCATTGTCATCAC
GTCAGAGAAAAATCTTCAGGGGTGCTAATCCTGTTGCATCAGTTGATCATACTAACGAGAACGGTAATGCGACAAGATACACATTGCCTT
CATCTGTACATTCTGTGATACCAGGCAAATTACCAATTACACACAGCTACTTATATTTTATGAAGGGCATTTTTTAGATGACCTCATCCT
CTGTGTTATTTGTTGATTGGGTTTGTTTTCTGTTTGTTGGTTTGTTTGTTTCTTCCACGTAAGGAAAAGTAGTGTAAACAGTAGCGAGAA
AATGGAAACCACAGAGGAAGATGTATTTTGCATGTTTTTCCTTTCAGTGTTCTTACACGTTGTATCACTGCATTGTGGTAATAGCTTCTA
TAAAATCTGCCATAGTTGGATTATGCAGCTTTGCAAAAATTTTTACTAGATTTTGCACTAACTCATATTAGCTTTGTCCTACCAACTTCT
GGAATTTATCTAATTATTGTTTTTCAAAGTTTCTTTCCTTTTAATGTTTCCCTGCTATGCAAAACCTTTCCCAGACCTCAGTTTCTTAAA
AGAAAGATGTTGCTACAGTTCCCGATTCTTTCTTATTACAGGCTCAGGTGTACAGGTTATTCTGGGTTAATTTTATCTAATGAAGCCCAT
TCCTTTTTGTACATAAAGATGTCACTTAAACTTATGCTTACAAACTAAAGACTAATCGCTCAATATGAAAACATGAAAAAATTTTTGCTT
AAAGTATTAAGATGGAAGTAGTTAAATATGGGTTATTTTGTCCTTTTACTTTTTTAAAAAATGTTACATATTGTATGCACTGTGCTGATG
CAAGAATTCTACATTTTAATGAGTTATAAAATTATTCTGCATCTCATCACGTCACAGTATTTCTGTACTATTTATTCATATATATAAATA
TATATGGGCTTAATCATTTAAAATTTGTTGCAGCAAGAACTTTCCTACCTGTAGGCAATAGATTGCTATGTTTTTAACAAATTGTGGCAA

>64664_64664_15_PGS1-BPTF_PGS1_chr17_76400170_ENST00000329897_BPTF_chr17_65916131_ENST00000335221_length(amino acids)=1390AA_BP=422
MRRDPCSGGDCWASCLAAQGWPRSWDACPTASAGTGTASAGAVPQVTSPPCCLCPEGVHRFQWIRNLVPEFGVSSSHVRVLSSPAEFFEL
MKVDCLESTLEKSLQAKFPSNLKVSILLDFTRGSRGRKNSRTMLLPLLRRFPEQVRVSLFHTPHLRGLLRLLIPERFNETIGLQHIKVYL
FDNSVILSGANLSDSYFTNRQDRYVFLQDCAEIADFFTELVDAVGDVSLQLQGDDTVQVVDGMVHPYKGDRAEYCKAANKRVMDVINSAR
TRQQMLHAQTFHSNSLLTQEDAAAAGDRRPAPDTWIYPLIQMKPFEIQIDEIVTETLLTEAERGAKVYLTTGYFNLTQAYMDLVLGTRAE
YQILLASPEVNGFFGAKGVAGAIPAAYVHIERQFFSEVCSLGQQERVQLQEYWRRGWTFHAKETSETEITTTEIIKRRDVGPYGIRSEYC
IRKIICPIGVPETPKETPTPQRKGLRSSALRPKRPETPKQTGPVIIETWVAEEELELWEIRAFAERVEKEKAQAVEQQAKKRLEQQKPTV
IATSTTSPTSSTTSTISPAQKVMVAPISGSVTTGTKMVLTTKVGSPATVTFQQNKNFHQTFATWVKQGQSNSGVVQVQQKVLGIIPSSTG
TSQQTFTSFQPRTATVTIRPNTSGSGGTTSNSQVITGPQIRPGMTVIRTPLQQSTLGKAIIRTPVMVQPGAPQQVMTQIIRGQPVSTAVS
APNTVSSTPGQKSLTSATSTSNIQSSASQPPRPQQGQVKLTMAQLTQLTQGHGGNQGLTVVIQGQGQTTGQLQLIPQGVTVLPGPGQQLM
QAAMPNGTVQRFLFTPLATTATTASTTTTTVSTTAAGTGEQRQSKLSPQMQVHQDKTLPPAQSSSVGPAEAQPQTAQPSAQPQPQTQPQS
PAQPEVQTQPEVQTQTTVSSHVPSEAQPTHAQSSKPQVAAQSQPQSNVQGQSPVRVQSPSQTRIRPSTPSQLSPGQQSQVQTTTSQPIPI
QPHTSLQIPSQGQPQSQPQVVMKHNAVIEHLKQKKSMTPAEREENQRMIVCNQVMKYILDKIDKEEKQAAKKRKREESVEQKRSKQNATK
LSALLFKHKEQLRAEILKKRALLDKDLQIEVQEELKRDLKIKKEKDLMQLAQATAVAAPCPPVTPAPPAPPAPPPSPPPPPAVQHTGLLS
TPTLPAASQKRKREEEKDSSSKSKKKKMISTTSKETKKDTKLYCICKTPYDESKFYIGCDRCQNWYHGRCVGILQSEAELIDEYVCPQCQ
STEDAMTVLTPLTEKDYEGLKRVLRSLQAHKMAWPFLEPVDPNDAPDYYGVIKEPMDLATMEERVQRRYYEKLTEFVADMTKIFDNCRYY

--------------------------------------------------------------
>64664_64664_16_PGS1-BPTF_PGS1_chr17_76400170_ENST00000329897_BPTF_chr17_65916131_ENST00000424123_length(transcript)=4196nt_BP=1290nt
CTCCATGGCGGTGGCGGCGGCAGCTGCGGCGGGACCCGTGTTCTGGAGGCGACTGCTGGGCCTCCTGCCTGGCCGCCCAGGGCTGGCCGC
GCTCCTGGGACGCCTGTCCGACCGCCTCGGCAGGAACCGGGACCGCCAGCGCAGGAGCTGTTCCCCAGGTCACCTCCCCACCTTGCTGCC
TGTGTCCAGAAGGCGTGCACCGGTTCCAGTGGATCAGAAACCTGGTTCCAGAATTTGGAGTCTCCAGTTCTCACGTTAGGGTGCTTTCTT
CCCCGGCAGAGTTTTTCGAGCTCATGAAGGTGGACTGCCTGGAAAGTACTCTAGAAAAGTCACTCCAAGCAAAGTTTCCTTCAAATCTCA
AGGTCTCCATTCTCTTAGACTTCACGCGGGGCTCACGAGGCCGGAAGAACTCCCGCACAATGCTGCTCCCACTCCTGCGGAGGTTCCCAG
AGCAGGTCCGAGTCTCCCTCTTTCACACGCCGCACCTCCGTGGGCTGCTTCGGCTCCTCATCCCTGAGCGCTTCAACGAGACCATCGGCC
TCCAGCACATTAAGGTGTACCTCTTCGACAACAGCGTCATCTTGAGCGGTGCAAACCTGAGTGACTCCTACTTCACCAACCGCCAGGACC
GCTACGTGTTCCTGCAGGACTGTGCGGAGATTGCCGACTTCTTCACGGAGCTGGTGGACGCGGTGGGGGATGTGTCCCTGCAGCTGCAGG
GGGACGACACGGTGCAGGTGGTGGATGGGATGGTGCATCCTTACAAAGGGGACCGGGCCGAGTACTGCAAGGCAGCCAATAAGAGGGTCA
TGGATGTGATCAACTCAGCCAGGACCCGCCAGCAGATGCTGCATGCCCAGACCTTCCACAGCAACTCTCTTTTGACCCAGGAAGATGCAG
CAGCTGCTGGGGATCGCAGACCAGCCCCTGACACCTGGATTTATCCGCTGATTCAGATGAAGCCCTTCGAGATTCAAATCGATGAGATTG
TCACTGAGACCCTGTTGACTGAGGCGGAGCGCGGGGCAAAGGTCTACCTCACCACTGGCTATTTCAACCTGACCCAGGCCTACATGGACC
TGGTCTTGGGCACTCGGGCTGAGTACCAGATCCTGCTGGCCTCACCAGAGGTGAATGGCTTCTTTGGGGCCAAGGGGGTGGCCGGCGCCA
TCCCAGCGGCCTATGTGCACATCGAGCGACAGTTCTTCAGTGAGGTGTGCAGCCTGGGACAGCAGGAGCGGGTCCAGCTTCAGGAGTACT
GGCGGAGGGGCTGGACGTTCCACGCCAAAGAAACATCCGAAACTGAAATCACAACAACAGAAATAATTAAGAGGAGAGATGTTGGTCCTT
ATGGCATTCGATCTGAATATTGTATCAGGAAAATCATTTGTCCCATTGGAGTTCCAGAAACACCAAAAGAAACGCCTACACCTCAGAGGA
AAGGCCTTCGATCAAGTGCACTGCGGCCAAAGAGACCAGAAACGCCCAAGCAAACTGGCCCTGTTATTATTGAAACCTGGGTAGCAGAAG
AAGAACTGGAATTGTGGGAGATCAGGGCATTTGCTGAGAGAGTGGAGAAAGAAAAGGCACAAGCAGTTGAGCAACAGGCTAAGAAACGAC
TGGAGCAGCAGAAGCCGACAGTGATTGCAACTTCCACTACTTCCCCAACAAGCAGTACAACCAGCACCATCTCTCCAGCACAGAAGGTTA
TGGTGGCCCCCATAAGTGGCTCAGTTACAACTGGAACCAAAATGGTACTAACTACTAAAGTTGGATCTCCAGCTACAGTAACATTCCAAC
AAAACAAGAACTTTCATCAAACCTTTGCTACATGGGTTAAGCAAGGCCAGTCAAATTCAGGCGTTGTTCAAGTACAGCAGAAAGTCCTGG
GTATCATTCCATCAAGTACAGGTACCAGTCAGCAAACCTTTACTTCATTCCAGCCCAGGACAGCAACAGTCACAATTAGGCCCAATACCT
CAGGCTCTGGAGGAACCACAAGCAATTCACAAGTAATCACAGGGCCTCAGATTCGCCCTGGTATGACCGTGATTAGAACACCACTCCAAC
AGTCAACACTAGGAAAGGCAATTATTCGAACACCTGTGATGGTACAGCCAGGTGCTCCTCAGCAAGTGATGACTCAAATCATCAGGGGGC
AGCCTGTCTCCACTGCAGTCTCCGCCCCTAACACGGTTTCCTCAACACCTGGGCAGAAAAGCTTAACTTCAGCAACGTCCACTTCAAATA
TACAGTCTTCAGCCTCACAACCCCCTCGCCCCCAACAAGGACAAGTGAAGCTCACCATGGCTCAACTTACTCAGTTAACACAGGGCCACG
GTGGCAATCAAGGTTTGACAGTAGTAATTCAAGGACAAGGTCAAACTACTGGACAGTTGCAGTTGATACCTCAAGGGGTGACTGTACTCC
CAGGCCCAGGCCAGCAGCTAATGCAAGCTGCAATGCCAAATGGTACTGTTCAGCGATTCCTCTTTACCCCATTGGCAACAACAGCCACCA
CAGCCAGCACCACCACCACCACTGTTTCCACGACAGCAGCAGGTACAGGTGAACAAAGGCAGAGTAAACTGTCACCCCAGATGCAGGTAC
ATCAAGACAAAACCCTGCCACCAGCTCAGTCATCAAGTGTGGGTCCAGCAGAAGCCCAGCCACAGACTGCTCAGCCTTCAGCTCAGCCCC
AGCCCCAAACCCAGCCCCAGTCCCCAGCTCAGCCTGAAGTTCAGACTCAGCCTGAAGTTCAGACCCAAACAACTGTTTCATCCCATGTCC
CTTCTGAAGCACAACCCACCCACGCACAGTCATCCAAGCCCCAAGTTGCAGCACAGTCTCAGCCTCAAAGTAATGTCCAAGGACAGTCTC
CTGTTCGTGTCCAAAGTCCATCACAGACTCGAATACGTCCATCAACTCCATCCCAACTGTCTCCTGGACAACAATCCCAGGTTCAGACTA
CAACCTCACAACCGATTCCAATTCAACCACATACATCTCTTCAGATACCTTCCCAAGGCCAGCCACAGTCACAACCCCAGGTGGTGATGA
AGCATAATGCTGTAATAGAACATTTAAAACAGAAAAAGAGCATGACTCCAGCTGAAAGAGAAGAGAATCAAAGAATGATTGTCTGTAACC
AGGTGATGAAGTATATTTTGGATAAGATAGATAAAGAAGAAAAACAGGCAGCAAAAAAACGGAAGCGTGAAGAGAGTGTGGAGCAGAAAC
GTAGCAAGCAGAATGCCACTAAGCTGTCAGCTCTGCTCTTCAAGCACAAAGAGCAGCTCAGAGCCGAGATCCTGAAGAAGAGAGCACTCC
TGGACAAGGATCTGCAAATTGAAGTGCAGGAAGAGCTGAAGAGAGACCTGAAAATTAAGAAAGAAAAAGACCTGATGCAGTTGGCTCAGG
CCACAGCAGTAGCTGCACCCTGCCCCCCAGTGACACCAGCTCCTCCAGCCCCTCCAGCCCCTCCACCTTCACCTCCCCCTCCACCTGCTG
TGCAACACACAGGCCTTCTGTCCACGCCCACCTTACCTGCTGCTTCCCAGAAGAGGAAGCGGGAAGAGGAAAAAGACTCCAGCTCAAAGT
CCAAGAAAAAGAAAATGATCTCTACTACCTCAAAGGAAACTAAGAAGGACACAAAGCTTTACTGTATCTGTAAAACGCCTTATGATGAAT
CTAAATTTTATATTGGCTGTGATCGGTGTCAGAATTGGTACCATGGGCGCTGCGTTGGCATCTTGCAAAGTGAGGCAGAGCTCATTGATG
AGTATGTCTGTCCACAGTGCCAGTCAACAGAGGATGCCATGACAGTGCTCACGCCACTAACAGAGAAGGATTATGAGGGGTTGAAGAGGG
TGCTCCGTTCCTTACAGGCCCATAAGATGGCCTGGCCTTTCCTTGAACCAGTAGACCCTAATGATGCACCAGATTATTATGGTGTTATTA
AGGAACCTATGGACCTTGCCACCATGGAAGAAAGAGTACAAAGACGATATTATGAAAAGCTGACGGAATTTGTGGCAGATATGACCAAAA
TTTTTGATAACTGTCGTTACTACAATCCAAGTGACTCCCCATTTTACCAGTGTGCAGAAGTTCTCGAATCATTCTTTGTACAGAAATTGA

>64664_64664_16_PGS1-BPTF_PGS1_chr17_76400170_ENST00000329897_BPTF_chr17_65916131_ENST00000424123_length(amino acids)=1391AA_BP=422
MRRDPCSGGDCWASCLAAQGWPRSWDACPTASAGTGTASAGAVPQVTSPPCCLCPEGVHRFQWIRNLVPEFGVSSSHVRVLSSPAEFFEL
MKVDCLESTLEKSLQAKFPSNLKVSILLDFTRGSRGRKNSRTMLLPLLRRFPEQVRVSLFHTPHLRGLLRLLIPERFNETIGLQHIKVYL
FDNSVILSGANLSDSYFTNRQDRYVFLQDCAEIADFFTELVDAVGDVSLQLQGDDTVQVVDGMVHPYKGDRAEYCKAANKRVMDVINSAR
TRQQMLHAQTFHSNSLLTQEDAAAAGDRRPAPDTWIYPLIQMKPFEIQIDEIVTETLLTEAERGAKVYLTTGYFNLTQAYMDLVLGTRAE
YQILLASPEVNGFFGAKGVAGAIPAAYVHIERQFFSEVCSLGQQERVQLQEYWRRGWTFHAKETSETEITTTEIIKRRDVGPYGIRSEYC
IRKIICPIGVPETPKETPTPQRKGLRSSALRPKRPETPKQTGPVIIETWVAEEELELWEIRAFAERVEKEKAQAVEQQAKKRLEQQKPTV
IATSTTSPTSSTTSTISPAQKVMVAPISGSVTTGTKMVLTTKVGSPATVTFQQNKNFHQTFATWVKQGQSNSGVVQVQQKVLGIIPSSTG
TSQQTFTSFQPRTATVTIRPNTSGSGGTTSNSQVITGPQIRPGMTVIRTPLQQSTLGKAIIRTPVMVQPGAPQQVMTQIIRGQPVSTAVS
APNTVSSTPGQKSLTSATSTSNIQSSASQPPRPQQGQVKLTMAQLTQLTQGHGGNQGLTVVIQGQGQTTGQLQLIPQGVTVLPGPGQQLM
QAAMPNGTVQRFLFTPLATTATTASTTTTTVSTTAAGTGEQRQSKLSPQMQVHQDKTLPPAQSSSVGPAEAQPQTAQPSAQPQPQTQPQS
PAQPEVQTQPEVQTQTTVSSHVPSEAQPTHAQSSKPQVAAQSQPQSNVQGQSPVRVQSPSQTRIRPSTPSQLSPGQQSQVQTTTSQPIPI
QPHTSLQIPSQGQPQSQPQVVMKHNAVIEHLKQKKSMTPAEREENQRMIVCNQVMKYILDKIDKEEKQAAKKRKREESVEQKRSKQNATK
LSALLFKHKEQLRAEILKKRALLDKDLQIEVQEELKRDLKIKKEKDLMQLAQATAVAAPCPPVTPAPPAPPAPPPSPPPPPAVQHTGLLS
TPTLPAASQKRKREEEKDSSSKSKKKKMISTTSKETKKDTKLYCICKTPYDESKFYIGCDRCQNWYHGRCVGILQSEAELIDEYVCPQCQ
STEDAMTVLTPLTEKDYEGLKRVLRSLQAHKMAWPFLEPVDPNDAPDYYGVIKEPMDLATMEERVQRRYYEKLTEFVADMTKIFDNCRYY

--------------------------------------------------------------

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Fusion Gene PPI Analysis for PGS1-BPTF


check button Go to ChiPPI (Chimeric Protein-Protein interactions) to see the chimeric PPI interaction in

ChiPPI page.


check button Protein-protein interactors with each fusion partner protein in wild-type (BIOGRID-3.4.160)
HgeneHgene's interactorsTgeneTgene's interactors


check button - Retained PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenStill interaction with


check button - Lost PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with
TgeneBPTFchr17:76400170chr17:65916130ENST000003063781128640_7491809.33333333333332921.0KEAP1
TgeneBPTFchr17:76400170chr17:65916130ENST000003218921330640_7491935.33333333333333047.0KEAP1
TgeneBPTFchr17:76400170chr17:65916130ENST000003352211330640_7491935.33333333333332904.0KEAP1
TgeneBPTFchr17:76400170chr17:65916131ENST000003063781128640_7491809.33333333333332921.0KEAP1
TgeneBPTFchr17:76400170chr17:65916131ENST000003218921330640_7491935.33333333333333047.0KEAP1
TgeneBPTFchr17:76400170chr17:65916131ENST000003352211330640_7491935.33333333333332904.0KEAP1
TgeneBPTFchr17:76400170chr17:65916130ENST000003063781128839_9211809.33333333333332921.0MAZ
TgeneBPTFchr17:76400170chr17:65916130ENST000003218921330839_9211935.33333333333333047.0MAZ
TgeneBPTFchr17:76400170chr17:65916130ENST000003352211330839_9211935.33333333333332904.0MAZ
TgeneBPTFchr17:76400170chr17:65916131ENST000003063781128839_9211809.33333333333332921.0MAZ
TgeneBPTFchr17:76400170chr17:65916131ENST000003218921330839_9211935.33333333333333047.0MAZ
TgeneBPTFchr17:76400170chr17:65916131ENST000003352211330839_9211935.33333333333332904.0MAZ


check button - Retained PPIs, but lost function due to frame-shift fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


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Related Drugs for PGS1-BPTF


check button Drugs targeting genes involved in this fusion gene.
(DrugBank Version 5.1.8 2021-05-08)
PartnerGeneUniProtAccDrugBank IDDrug nameDrug activityDrug typeDrug status

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Related Diseases for PGS1-BPTF


check button Diseases associated with fusion partners.
(DisGeNet 4.0)
PartnerGeneDisease IDDisease name# pubmedsSource