FusionGDB Logo

Home

Download

Statistics

Examples

Help

Contact
Center for Computational Systems Medicine
leaf

Fusion Gene Summary

leaf

Fusion Gene ORF analysis

leaf

Fusion Genomic Features

leaf

Fusion Protein Features

leaf

Fusion Gene Sequence

leaf

Fusion Gene PPI analysis

leaf

Related Drugs

leaf

Related Diseases

Fusion gene:ARID4B-TOMM20 (FusionGDB2 ID:6490)

Fusion Gene Summary for ARID4B-TOMM20

check button Fusion gene summary
Fusion gene informationFusion gene name: ARID4B-TOMM20
Fusion gene ID: 6490
HgeneTgene
Gene symbol

ARID4B

TOMM20

Gene ID

51742

9804

Gene nameAT-rich interaction domain 4Btranslocase of outer mitochondrial membrane 20
SynonymsBCAA|BRCAA1|RBBP1L1|RBP1L1|SAP180MAS20|MOM19|TOM20
Cytomap

1q42.3

1q42.3

Type of geneprotein-codingprotein-coding
DescriptionAT-rich interactive domain-containing protein 4B180 kDa Sin3-associated polypeptideARID domain-containing protein 4BAT rich interactive domain 4B (RBP1-like)Rb-binding protein homologSIN3A-associated protein 180breast cancer-associated antigen 1bremitochondrial import receptor subunit TOM20 homologmitochondrial 20 kDa outer membrane proteinouter mitochondrial membrane receptor Tom20translocase of outer mitochondrial membrane 20 homolog type II
Modification date2020032020200313
UniProtAcc

Q4LE39

.
Ensembl transtripts involved in fusion geneENST00000264183, ENST00000349213, 
ENST00000366603, ENST00000494543, 
ENST00000467767, ENST00000366607, 
Fusion gene scores* DoF score23 X 20 X 9=41407 X 6 X 4=168
# samples 299
** MAII scorelog2(29/4140*10)=-3.83550596237175
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0		log2(9/168*10)=-0.900464326449086
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0
Context

PubMed: ARID4B [Title/Abstract] AND TOMM20 [Title/Abstract] AND fusion [Title/Abstract]

Most frequent breakpointARID4B(235490229)-TOMM20(235285687), # samples:2
TOMM20(235291910)-ARID4B(235295312), # samples:1
Anticipated loss of major functional domain due to fusion event.ARID4B-TOMM20 seems lost the major protein functional domain in Hgene partner, which is a epigenetic factor due to the frame-shifted ORF.
ARID4B-TOMM20 seems lost the major protein functional domain in Hgene partner, which is a essential gene due to the frame-shifted ORF.
ARID4B-TOMM20 seems lost the major protein functional domain in Tgene partner, which is a cell metabolism gene due to the frame-shifted ORF.
ARID4B-TOMM20 seems lost the major protein functional domain in Tgene partner, which is a essential gene due to the frame-shifted ORF.
* DoF score (Degree of Frequency) = # partners X # break points X # cancer types
** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10)

check button Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez
PartnerGeneGO IDGO termPubMed ID
TgeneTOMM20

GO:0006626

protein targeting to mitochondrion

14557246


check buttonFusion gene breakpoints across ARID4B (5'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.
all structure

check buttonFusion gene breakpoints across TOMM20 (3'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.
all structure

check button Fusion gene information from two resources (ChiTars 5.0 and ChimerDB 4.0)
* All genome coordinats were lifted-over on hg19.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
SourceDiseaseSampleHgeneHchrHbpHstrandTgeneTchrTbpTstrand
ChimerDB4BRCATCGA-AC-A6IW-01AARID4Bchr1

235490229

-TOMM20chr1

235285687

-
ChimerDB4STADTCGA-CG-4441-01AARID4Bchr1

235416045

-TOMM20chr1

235275423

-
ChimerDB4STADTCGA-D7-6822-01AARID4Bchr1

235490229

-TOMM20chr1

235285687

-
ChimerDB4STADTCGA-D7-6822ARID4Bchr1

235490228

-TOMM20chr1

235285687

-


Top

Fusion Gene ORF analysis for ARID4B-TOMM20

check button Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
ORFHenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrand
5CDS-5UTRENST00000264183ENST00000467767ARID4Bchr1

235416045

-TOMM20chr1

235275423

-
5CDS-5UTRENST00000349213ENST00000467767ARID4Bchr1

235416045

-TOMM20chr1

235275423

-
5CDS-5UTRENST00000366603ENST00000467767ARID4Bchr1

235416045

-TOMM20chr1

235275423

-
5CDS-intronENST00000264183ENST00000467767ARID4Bchr1

235490229

-TOMM20chr1

235285687

-
5CDS-intronENST00000264183ENST00000467767ARID4Bchr1

235490228

-TOMM20chr1

235285687

-
5CDS-intronENST00000349213ENST00000467767ARID4Bchr1

235490229

-TOMM20chr1

235285687

-
5CDS-intronENST00000349213ENST00000467767ARID4Bchr1

235490228

-TOMM20chr1

235285687

-
5CDS-intronENST00000366603ENST00000467767ARID4Bchr1

235490229

-TOMM20chr1

235285687

-
5CDS-intronENST00000366603ENST00000467767ARID4Bchr1

235490228

-TOMM20chr1

235285687

-
Frame-shiftENST00000264183ENST00000366607ARID4Bchr1

235416045

-TOMM20chr1

235275423

-
Frame-shiftENST00000349213ENST00000366607ARID4Bchr1

235416045

-TOMM20chr1

235275423

-
Frame-shiftENST00000366603ENST00000366607ARID4Bchr1

235416045

-TOMM20chr1

235275423

-
In-frameENST00000264183ENST00000366607ARID4Bchr1

235490229

-TOMM20chr1

235285687

-
In-frameENST00000264183ENST00000366607ARID4Bchr1

235490228

-TOMM20chr1

235285687

-
In-frameENST00000349213ENST00000366607ARID4Bchr1

235490229

-TOMM20chr1

235285687

-
In-frameENST00000349213ENST00000366607ARID4Bchr1

235490228

-TOMM20chr1

235285687

-
In-frameENST00000366603ENST00000366607ARID4Bchr1

235490229

-TOMM20chr1

235285687

-
In-frameENST00000366603ENST00000366607ARID4Bchr1

235490228

-TOMM20chr1

235285687

-
intron-3CDSENST00000494543ENST00000366607ARID4Bchr1

235490229

-TOMM20chr1

235285687

-
intron-3CDSENST00000494543ENST00000366607ARID4Bchr1

235416045

-TOMM20chr1

235275423

-
intron-3CDSENST00000494543ENST00000366607ARID4Bchr1

235490228

-TOMM20chr1

235285687

-
intron-5UTRENST00000494543ENST00000467767ARID4Bchr1

235416045

-TOMM20chr1

235275423

-
intron-intronENST00000494543ENST00000467767ARID4Bchr1

235490229

-TOMM20chr1

235285687

-
intron-intronENST00000494543ENST00000467767ARID4Bchr1

235490228

-TOMM20chr1

235285687

-

check buttonORFfinder result based on the fusion transcript sequence of in-frame fusion genes.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandSeq length
(transcript)		BP loci
(transcript)		Predicted start
(transcript)		Predicted stop
(transcript)		Seq length
(amino acids)
ENST00000366603ARID4Bchr1235490228-ENST00000366607TOMM20chr1235285687-34283833023969
ENST00000264183ARID4Bchr1235490228-ENST00000366607TOMM20chr1235285687-354950440501153
ENST00000349213ARID4Bchr1235490228-ENST00000366607TOMM20chr1235285687-355150642503153
ENST00000366603ARID4Bchr1235490229-ENST00000366607TOMM20chr1235285687-34283833023969
ENST00000264183ARID4Bchr1235490229-ENST00000366607TOMM20chr1235285687-354950440501153
ENST00000349213ARID4Bchr1235490229-ENST00000366607TOMM20chr1235285687-355150642503153

check buttonDeepORF prediction of the coding potential based on the fusion transcript sequence of in-frame fusion genes. DeepORF is a coding potential classifier based on convolutional neural network by comparing the real Ribo-seq data. If the no-coding score < 0.5 and coding score > 0.5, then the in-frame fusion transcript is predicted as being likely translated.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandNo-coding scoreCoding score
ENST00000366603ENST00000366607ARID4Bchr1235490228-TOMM20chr1235285687-0.8776380.12236198
ENST00000264183ENST00000366607ARID4Bchr1235490228-TOMM20chr1235285687-0.88973710.11026291
ENST00000349213ENST00000366607ARID4Bchr1235490228-TOMM20chr1235285687-0.8903220.10967798
ENST00000366603ENST00000366607ARID4Bchr1235490229-TOMM20chr1235285687-0.8776380.12236198
ENST00000264183ENST00000366607ARID4Bchr1235490229-TOMM20chr1235285687-0.88973710.11026291
ENST00000349213ENST00000366607ARID4Bchr1235490229-TOMM20chr1235285687-0.8903220.10967798

Top

Fusion Genomic Features for ARID4B-TOMM20


check buttonFusionAI prediction of the potential fusion gene breakpoint based on the pre-mature RNA sequence context (+/- 5kb of individual partner genes, total 20kb length sequence). FusionAI is a fusion gene breakpoint classifier based on convolutional neural network by comparing the fusion positive and negative sequence context of ~ 20K fusion gene data. From here, we can have the relative potentency of the 20K genomic sequence how individual sequnce will be likely used as the gene fusion breakpoints.
HgeneHchrHbpHstrandTgeneTchrTbpTstrand1-pp (fusion gene breakpoint)

check buttonDistribution of 44 human genomic features loci across 20kb length fusion breakpoint regions. We integrated a total of 44 different types of human genomic feature loci information across five big categories including virus integration sites, repeats, structural variants, chromatin states, and gene expression regulation. More details are in help page.
genomic feature

check buttonDistribution of 44 human genomic features loci across 20kb length fusion breakpoint regions that are ovelapped with the top 1% feature importance score regions. More details are in help page.

Top

Fusion Protein Features for ARID4B-TOMM20


check button Four levels of functional features of fusion genes
Go to FGviewer search page for the most frequent breakpoint (https://ccsmweb.uth.edu/FGviewer/chr1:235490229/chr1:235285687)
- FGviewer provides the online visualization of the retention search of the protein functional features across DNA, RNA, protein, and pathological levels.
- How to search
1. Put your fusion gene symbol.
2. Press the tab key until there will be shown the breakpoint information filled.
4. Go down and press 'Search' tab twice.
4. Go down to have the hyperlink of the search result.
5. Click the hyperlink.
6. See the FGviewer result for your fusion gene.
FGviewer

check buttonMain function of each fusion partner protein. (from UniProt)
HgeneTgene
ARID4B

Q4LE39

.
FUNCTION: Acts as a transcriptional repressor (PubMed:12724404). May function in the assembly and/or enzymatic activity of the Sin3A corepressor complex or in mediating interactions between the complex and other regulatory complexes (PubMed:12724404). Plays a role in the regulation of epigenetic modifications at the PWS/AS imprinting center near the SNRPN promoter, where it might function as part of a complex with RB1 and ARID4A. Involved in spermatogenesis, together with ARID4A, where it functions as a transcriptional coactivator for AR (androgen receptor) and enhances expression of genes required for sperm maturation. Regulates expression of the tight junction protein CLDN3 in the testis, which is important for integrity of the blood-testis barrier. Plays a role in myeloid homeostasis where it regulates the histone methylation state of bone marrow cells and expression of various genes involved in hematopoiesis. May function as a leukemia suppressor (By similarity). {ECO:0000250|UniProtKB:A2CG63, ECO:0000269|PubMed:12724404}.FUNCTION: Transcriptional activator which is required for calcium-dependent dendritic growth and branching in cortical neurons. Recruits CREB-binding protein (CREBBP) to nuclear bodies. Component of the CREST-BRG1 complex, a multiprotein complex that regulates promoter activation by orchestrating a calcium-dependent release of a repressor complex and a recruitment of an activator complex. In resting neurons, transcription of the c-FOS promoter is inhibited by BRG1-dependent recruitment of a phospho-RB1-HDAC1 repressor complex. Upon calcium influx, RB1 is dephosphorylated by calcineurin, which leads to release of the repressor complex. At the same time, there is increased recruitment of CREBBP to the promoter by a CREST-dependent mechanism, which leads to transcriptional activation. The CREST-BRG1 complex also binds to the NR2B promoter, and activity-dependent induction of NR2B expression involves a release of HDAC1 and recruitment of CREBBP (By similarity). {ECO:0000250}.

check buttonRetention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at

download page


* Minus value of BPloci means that the break pointn is located before the CDS.
- In-frame and retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note

- In-frame and not-retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
HgeneARID4Bchr1:235490228chr1:235285687ENST00000264183-2241231_127021313.0Coiled coilOntology_term=ECO:0000255
HgeneARID4Bchr1:235490228chr1:235285687ENST00000264183-224728_75421313.0Coiled coilOntology_term=ECO:0000255
HgeneARID4Bchr1:235490228chr1:235285687ENST00000349213-2231231_127021227.0Coiled coilOntology_term=ECO:0000255
HgeneARID4Bchr1:235490228chr1:235285687ENST00000349213-223728_75421227.0Coiled coilOntology_term=ECO:0000255
HgeneARID4Bchr1:235490228chr1:235285687ENST00000366603-2241231_127021313.0Coiled coilOntology_term=ECO:0000255
HgeneARID4Bchr1:235490228chr1:235285687ENST00000366603-224728_75421313.0Coiled coilOntology_term=ECO:0000255
HgeneARID4Bchr1:235490229chr1:235285687ENST00000264183-2241231_127021313.0Coiled coilOntology_term=ECO:0000255
HgeneARID4Bchr1:235490229chr1:235285687ENST00000264183-224728_75421313.0Coiled coilOntology_term=ECO:0000255
HgeneARID4Bchr1:235490229chr1:235285687ENST00000349213-2231231_127021227.0Coiled coilOntology_term=ECO:0000255
HgeneARID4Bchr1:235490229chr1:235285687ENST00000349213-223728_75421227.0Coiled coilOntology_term=ECO:0000255
HgeneARID4Bchr1:235490229chr1:235285687ENST00000366603-2241231_127021313.0Coiled coilOntology_term=ECO:0000255
HgeneARID4Bchr1:235490229chr1:235285687ENST00000366603-224728_75421313.0Coiled coilOntology_term=ECO:0000255
HgeneARID4Bchr1:235490228chr1:235285687ENST00000264183-2241095_110121313.0Compositional biasNote=Poly-Ser
HgeneARID4Bchr1:235490228chr1:235285687ENST00000264183-2241271_130321313.0Compositional biasNote=Ser-rich
HgeneARID4Bchr1:235490228chr1:235285687ENST00000264183-224154_15921313.0Compositional biasNote=Poly-Ser
HgeneARID4Bchr1:235490228chr1:235285687ENST00000264183-224268_56721313.0Compositional biasNote=Glu-rich
HgeneARID4Bchr1:235490228chr1:235285687ENST00000349213-2231095_110121227.0Compositional biasNote=Poly-Ser
HgeneARID4Bchr1:235490228chr1:235285687ENST00000349213-2231271_130321227.0Compositional biasNote=Ser-rich
HgeneARID4Bchr1:235490228chr1:235285687ENST00000349213-223154_15921227.0Compositional biasNote=Poly-Ser
HgeneARID4Bchr1:235490228chr1:235285687ENST00000349213-223268_56721227.0Compositional biasNote=Glu-rich
HgeneARID4Bchr1:235490228chr1:235285687ENST00000366603-2241095_110121313.0Compositional biasNote=Poly-Ser
HgeneARID4Bchr1:235490228chr1:235285687ENST00000366603-2241271_130321313.0Compositional biasNote=Ser-rich
HgeneARID4Bchr1:235490228chr1:235285687ENST00000366603-224154_15921313.0Compositional biasNote=Poly-Ser
HgeneARID4Bchr1:235490228chr1:235285687ENST00000366603-224268_56721313.0Compositional biasNote=Glu-rich
HgeneARID4Bchr1:235490229chr1:235285687ENST00000264183-2241095_110121313.0Compositional biasNote=Poly-Ser
HgeneARID4Bchr1:235490229chr1:235285687ENST00000264183-2241271_130321313.0Compositional biasNote=Ser-rich
HgeneARID4Bchr1:235490229chr1:235285687ENST00000264183-224154_15921313.0Compositional biasNote=Poly-Ser
HgeneARID4Bchr1:235490229chr1:235285687ENST00000264183-224268_56721313.0Compositional biasNote=Glu-rich
HgeneARID4Bchr1:235490229chr1:235285687ENST00000349213-2231095_110121227.0Compositional biasNote=Poly-Ser
HgeneARID4Bchr1:235490229chr1:235285687ENST00000349213-2231271_130321227.0Compositional biasNote=Ser-rich
HgeneARID4Bchr1:235490229chr1:235285687ENST00000349213-223154_15921227.0Compositional biasNote=Poly-Ser
HgeneARID4Bchr1:235490229chr1:235285687ENST00000349213-223268_56721227.0Compositional biasNote=Glu-rich
HgeneARID4Bchr1:235490229chr1:235285687ENST00000366603-2241095_110121313.0Compositional biasNote=Poly-Ser
HgeneARID4Bchr1:235490229chr1:235285687ENST00000366603-2241271_130321313.0Compositional biasNote=Ser-rich
HgeneARID4Bchr1:235490229chr1:235285687ENST00000366603-224154_15921313.0Compositional biasNote=Poly-Ser
HgeneARID4Bchr1:235490229chr1:235285687ENST00000366603-224268_56721313.0Compositional biasNote=Glu-rich
HgeneARID4Bchr1:235490228chr1:235285687ENST00000264183-224306_39821313.0DomainARID
HgeneARID4Bchr1:235490228chr1:235285687ENST00000349213-223306_39821227.0DomainARID
HgeneARID4Bchr1:235490228chr1:235285687ENST00000366603-224306_39821313.0DomainARID
HgeneARID4Bchr1:235490229chr1:235285687ENST00000264183-224306_39821313.0DomainARID
HgeneARID4Bchr1:235490229chr1:235285687ENST00000349213-223306_39821227.0DomainARID
HgeneARID4Bchr1:235490229chr1:235285687ENST00000366603-224306_39821313.0DomainARID
HgeneARID4Bchr1:235490228chr1:235285687ENST00000264183-2241130_113721313.0RegionNote=Antigenic epitope
HgeneARID4Bchr1:235490228chr1:235285687ENST00000264183-224465_47321313.0RegionNote=Antigenic epitope
HgeneARID4Bchr1:235490228chr1:235285687ENST00000349213-2231130_113721227.0RegionNote=Antigenic epitope
HgeneARID4Bchr1:235490228chr1:235285687ENST00000349213-223465_47321227.0RegionNote=Antigenic epitope
HgeneARID4Bchr1:235490228chr1:235285687ENST00000366603-2241130_113721313.0RegionNote=Antigenic epitope
HgeneARID4Bchr1:235490228chr1:235285687ENST00000366603-224465_47321313.0RegionNote=Antigenic epitope
HgeneARID4Bchr1:235490229chr1:235285687ENST00000264183-2241130_113721313.0RegionNote=Antigenic epitope
HgeneARID4Bchr1:235490229chr1:235285687ENST00000264183-224465_47321313.0RegionNote=Antigenic epitope
HgeneARID4Bchr1:235490229chr1:235285687ENST00000349213-2231130_113721227.0RegionNote=Antigenic epitope
HgeneARID4Bchr1:235490229chr1:235285687ENST00000349213-223465_47321227.0RegionNote=Antigenic epitope
HgeneARID4Bchr1:235490229chr1:235285687ENST00000366603-2241130_113721313.0RegionNote=Antigenic epitope
HgeneARID4Bchr1:235490229chr1:235285687ENST00000366603-224465_47321313.0RegionNote=Antigenic epitope
TgeneTOMM20chr1:235490228chr1:235285687ENST00000366607051_640146.0Topological domainMitochondrial intermembrane
TgeneTOMM20chr1:235490228chr1:235285687ENST000003666070525_14540146.0Topological domainCytoplasmic
TgeneTOMM20chr1:235490229chr1:235285687ENST00000366607051_640146.0Topological domainMitochondrial intermembrane
TgeneTOMM20chr1:235490229chr1:235285687ENST000003666070525_14540146.0Topological domainCytoplasmic
TgeneTOMM20chr1:235490228chr1:235285687ENST00000366607057_2440146.0TransmembraneHelical
TgeneTOMM20chr1:235490229chr1:235285687ENST00000366607057_2440146.0TransmembraneHelical


Top

Fusion Gene Sequence for ARID4B-TOMM20


check button For in-frame fusion transcripts, we provide the fusion transcript sequences and fusion amino acid sequences. To have fusion amino acid sequence, we ran ORFfinder and chose the longest ORF among the all predicted ones.
>6490_6490_1_ARID4B-TOMM20_ARID4B_chr1_235490228_ENST00000264183_TOMM20_chr1_235285687_ENST00000366607_length(transcript)=3549nt_BP=504nt
AAAGGGGGGGAACCTAGAGTCGGTGGGGGGGAAGCGATGTTTGCCCGTCAGTCGAGTCCGGAGTGAGGAGCTCGGTCGCCGAAGCGGAGG
GAGACTCTTGAGCTTCATCTTGCCGCCGCCACGGCCACCGCCTGGACCTTTGCCCGGAGGGAGCTGCAGAGGGTCCATCGCCGCCGTCCT
CTGGAGGGCAGCGCGATTGGGGGCCCGGACCTCCAGTCCGGGGGGGATTTTTCGTCGTCCCCCTCCCCCCAACCAGGGAGCCCGAGCGGC
CGCCAAACAAAGGTACCAGTCGCCGCCGCGGGAGGAGGAGGAGCCGGAGCCTCTGCCTCAGCAGCCGCTGGACCCGCCGCCCTTCTTCCC
CATCTCTCCCCCGGGCCTGCTGGTTTTGGGGGGGAGAAGGAGAGAGGGGACTCTGGACGTGCCAGGGTCAGATCTCGCCTCCGAGGAAGG
TGCAGCTGAACCTGGTGTTTTAGAGGATACCTTGGTCCCAGAGTCATCATGAAGGAAGAAAGAAACAGAAGCTTGCCAAGGAGAGAGCTG
GGCTTTCCAAGTTACCTGACCTTAAAGATGCTGAAGCTGTTCAGAAGTTCTTCCTTGAAGAAATACAGCTTGGTGAAGAGTTACTAGCTC
AAGGTGAATATGAGAAGGGCGTAGACCATCTGACAAATGCAATTGCTGTGTGTGGACAGCCACAGCAGTTACTGCAGGTCTTACAGCAAA
CTCTTCCACCACCAGTGTTCCAGATGCTTCTGACTAAGCTCCCAACAATTAGTCAGAGAATTGTAAGTGCTCAGAGCTTGGCTGAAGATG
ATGTGGAATGAGAAACAAATGTCAACATAATAAAATCTCAGTTAAAAATATTTTAAAAATTCTTGGTAGTTGAGCAGCTCTGGGGGAATA
AGGGCAAATATGCTTGTTATGAACTACACTGAAATCTACCAAAGTTAATGTTTACTTTGTGTAGATCCATTTGTCTATTTTATTTATTTT
TCCCAGTGAAAAGTGTATTTTGATAGAGAACTTTTCATTCTATAAATACACTATGAGTTACTAAAATATCATGGATTTTGTTTATTCCTG
AAACATAGTTACATAGTTAAACTGTACATATGACATGGCTTATGTTAAAAATACCCAGTGCTCAGTTTTGAAAGATAGGCAAAAAAAAAA
AAGTATAGGAGAAACTGAAGAATGTACACTTTTTTAGAGGGCACATTTTGCTGTAAATCTGGAAATTTGATAGACTTGACTGTGTTTGTG
AAAACTGAGCATTAAAGGTTTTGATTGATCCTTTCTTTCCATTTAATCTCTGAGACGTAAATATGTGAGGTGTGCTGCTGTGCTGGGTTA
ACAGCTTCCTTCCCTTTCTGTGTAGCAGTCTTGAAATGTTCTGTTTAAATCAGTAGGCTTAATGTGTTCTGGGTATTTATCTCCTTGTAT
TTTAAATATATGTAGTTGCAAATAGCACCAGGAATTAGATTTCTGTACACCCCTAATCTAGCCTTGTGAGCTTCGCTAGTTAATGTGTGC
TCACTTTCCCTCCATTTGTTACGTGAGAGAATGCGTCTGCTGATCACTGAAGTGTCCCTTTTAGCTTCTGATTCATTGGGTTCTGTTGGG
CATCTTTAAATCCACCTTAACCTGAGGAATGTATGTGGGCAACCAGGCCCTGCATTTTTTTATATTCTGAATTTTGCATGCTTGCCTGAC
TTAGTATTTCTGAATTGATGTTTTTTTTAATGGTATAACTATCTTGATTTTCACTGAAATTATATGGTTCTGTCACTACTCTGTAAATTA
ATCCGAAACTTTTAAGGTAACTGGGATGATCTGCTTGTAAAAATGCTTGTTGCCTTTTGCTTTATCTTCAGTGTACCTCCTTAATCCTGC
TTCAACTTGATTATCTTGTGAAACGATGAGAGTAAGTTGCAACCTTGTGACTGAAAACTTGAAAAGAGTGGAGCAGGTGGGACCTCTTAT
TCTCAAATAGTGACATATTCTCCGTAGTCACAGTTTCAGAACTGAGTAAGGATCCTTGGTACTTGGTGGCATCTGTTGAACTGAGGAGCA
TTTCTCATTGTAAAGATTGCCTTTGTTCTGTCTAAAAGTCTGGAGAAATCCCAAAGACTTTTCCTATGTACTAGGCATTTTATTTTGATT
GACTTACAAACTCTTCTTAATCATTATCAATCTCGGTTTTTTTGTGGTGCAGTGGAAGGAGAAATAGGTCTAGTTTCTGCCTCTGATTAG
CCGCACAGCCTTGAACAAATCACATTTCATCTTTGAACTTACCTCTACTGTTAGACTAGGCGACTCACATTTGAGGACTTTTCTCGGGTA
TCTTGAGGGTTTGTGATCCTGAACCCTTAAACAGTGCTTTTTTGTTACACAGGAGGGCTTTTTTGGGGGGATGACCAGTACAGACATGCC
AGTTAGTTTTACTAGTGGGATCCCAAATCCAAAGCAGTGTAGTGGTGATTGGTCAGTGACTAACCAGGCAGCTAAGAAGTCTTAGGCAGC
AGCCCAGACATGTATAGAGGGGCAGTTAGAGGGAGAACAGGGGTGGGAAAGGGAGCAAGGGGCAGATAGCTCAGCAAGGAAAGAATGGGC
TCAGAAAAAGGAGGGCTGGCTGGAGGAGTGAGGGGCAGCTTAAGTTTGGGGAGGGTAGAAACGCCGTTTCCTTGGGAACTGGAGTGCAGT
ATGAGCTGGGTGTCACTTGGCTCTGAACATACTGGCTTTGCTGTAATGCTTGAAAAGGCGTTGGTATCTTCATTTTACAGTTCATTAACC
CAAGTACGTTTTCTTATTTAAATGACAACTTTGGTGCTTTAAAATGAGGTACCACTTTTTAAAGCTAGCTGTGTCGAGTTAAAGAAAAAA
TCAGCAGTTTTTTCTCCCAGAAATGTAATTGCCAAACACTATTCATCCCCATCTTAAGTTTTACAAGGTGATGTAATCAGCTTGTTGTAG
TGATGCTGGCCAAATGGTGCTCAGCAGGTGAGAACAAAAAAACCCCAGATCTCAGTGAACTAATACACAGCTTGAGCGTTTCCATGTGCT
AATGTTGCACACTTACTAAAAAACTTTGGAAATGGAAAATAATGTATTAGTGCAACAGTTGATGTGCTTCTTTGGGCAAAGATATAGTTT
TGTTCCACAATTTGTACTTAAAAGCGAAAGAACATTGAAAACATAGACTTACTGGCTGTAGCAATGCTGGCCTGTTAACTGATAACTAGA
ACTTAGGTTCACGTTTATGTAAAGTGTGTAAAACCTAGTAGAGCTTGCATAGTCGGCACTCAGTAAATGTTTGGTTCCTTTTGCCCCTTG
GTAAGTTTATTTTACCATCCTCCCACCTGCCATTCTGACTTTATTAAATCAACATGTGGACCAGAGTGTTAATGAGATGTTATTGCAGAA
GAGATTGAGAAAATTGGTATATCATGCAGATAACATACAAAATCTTTTTGTAACGTAAAAAATGCAGTTTTATTATTGCTTGTGCCTCAA

>6490_6490_1_ARID4B-TOMM20_ARID4B_chr1_235490228_ENST00000264183_TOMM20_chr1_235285687_ENST00000366607_length(amino acids)=153AA_BP=
MPVSRVRSEELGRRSGGRLLSFILPPPRPPPGPLPGGSCRGSIAAVLWRAARLGARTSSPGGIFRRPPPPNQGARAAAKQRYQSPPREEE

--------------------------------------------------------------
>6490_6490_2_ARID4B-TOMM20_ARID4B_chr1_235490228_ENST00000349213_TOMM20_chr1_235285687_ENST00000366607_length(transcript)=3551nt_BP=506nt
AGAAAGGGGGGGAACCTAGAGTCGGTGGGGGGGAAGCGATGTTTGCCCGTCAGTCGAGTCCGGAGTGAGGAGCTCGGTCGCCGAAGCGGA
GGGAGACTCTTGAGCTTCATCTTGCCGCCGCCACGGCCACCGCCTGGACCTTTGCCCGGAGGGAGCTGCAGAGGGTCCATCGCCGCCGTC
CTCTGGAGGGCAGCGCGATTGGGGGCCCGGACCTCCAGTCCGGGGGGGATTTTTCGTCGTCCCCCTCCCCCCAACCAGGGAGCCCGAGCG
GCCGCCAAACAAAGGTACCAGTCGCCGCCGCGGGAGGAGGAGGAGCCGGAGCCTCTGCCTCAGCAGCCGCTGGACCCGCCGCCCTTCTTC
CCCATCTCTCCCCCGGGCCTGCTGGTTTTGGGGGGGAGAAGGAGAGAGGGGACTCTGGACGTGCCAGGGTCAGATCTCGCCTCCGAGGAA
GGTGCAGCTGAACCTGGTGTTTTAGAGGATACCTTGGTCCCAGAGTCATCATGAAGGAAGAAAGAAACAGAAGCTTGCCAAGGAGAGAGC
TGGGCTTTCCAAGTTACCTGACCTTAAAGATGCTGAAGCTGTTCAGAAGTTCTTCCTTGAAGAAATACAGCTTGGTGAAGAGTTACTAGC
TCAAGGTGAATATGAGAAGGGCGTAGACCATCTGACAAATGCAATTGCTGTGTGTGGACAGCCACAGCAGTTACTGCAGGTCTTACAGCA
AACTCTTCCACCACCAGTGTTCCAGATGCTTCTGACTAAGCTCCCAACAATTAGTCAGAGAATTGTAAGTGCTCAGAGCTTGGCTGAAGA
TGATGTGGAATGAGAAACAAATGTCAACATAATAAAATCTCAGTTAAAAATATTTTAAAAATTCTTGGTAGTTGAGCAGCTCTGGGGGAA
TAAGGGCAAATATGCTTGTTATGAACTACACTGAAATCTACCAAAGTTAATGTTTACTTTGTGTAGATCCATTTGTCTATTTTATTTATT
TTTCCCAGTGAAAAGTGTATTTTGATAGAGAACTTTTCATTCTATAAATACACTATGAGTTACTAAAATATCATGGATTTTGTTTATTCC
TGAAACATAGTTACATAGTTAAACTGTACATATGACATGGCTTATGTTAAAAATACCCAGTGCTCAGTTTTGAAAGATAGGCAAAAAAAA
AAAAGTATAGGAGAAACTGAAGAATGTACACTTTTTTAGAGGGCACATTTTGCTGTAAATCTGGAAATTTGATAGACTTGACTGTGTTTG
TGAAAACTGAGCATTAAAGGTTTTGATTGATCCTTTCTTTCCATTTAATCTCTGAGACGTAAATATGTGAGGTGTGCTGCTGTGCTGGGT
TAACAGCTTCCTTCCCTTTCTGTGTAGCAGTCTTGAAATGTTCTGTTTAAATCAGTAGGCTTAATGTGTTCTGGGTATTTATCTCCTTGT
ATTTTAAATATATGTAGTTGCAAATAGCACCAGGAATTAGATTTCTGTACACCCCTAATCTAGCCTTGTGAGCTTCGCTAGTTAATGTGT
GCTCACTTTCCCTCCATTTGTTACGTGAGAGAATGCGTCTGCTGATCACTGAAGTGTCCCTTTTAGCTTCTGATTCATTGGGTTCTGTTG
GGCATCTTTAAATCCACCTTAACCTGAGGAATGTATGTGGGCAACCAGGCCCTGCATTTTTTTATATTCTGAATTTTGCATGCTTGCCTG
ACTTAGTATTTCTGAATTGATGTTTTTTTTAATGGTATAACTATCTTGATTTTCACTGAAATTATATGGTTCTGTCACTACTCTGTAAAT
TAATCCGAAACTTTTAAGGTAACTGGGATGATCTGCTTGTAAAAATGCTTGTTGCCTTTTGCTTTATCTTCAGTGTACCTCCTTAATCCT
GCTTCAACTTGATTATCTTGTGAAACGATGAGAGTAAGTTGCAACCTTGTGACTGAAAACTTGAAAAGAGTGGAGCAGGTGGGACCTCTT
ATTCTCAAATAGTGACATATTCTCCGTAGTCACAGTTTCAGAACTGAGTAAGGATCCTTGGTACTTGGTGGCATCTGTTGAACTGAGGAG
CATTTCTCATTGTAAAGATTGCCTTTGTTCTGTCTAAAAGTCTGGAGAAATCCCAAAGACTTTTCCTATGTACTAGGCATTTTATTTTGA
TTGACTTACAAACTCTTCTTAATCATTATCAATCTCGGTTTTTTTGTGGTGCAGTGGAAGGAGAAATAGGTCTAGTTTCTGCCTCTGATT
AGCCGCACAGCCTTGAACAAATCACATTTCATCTTTGAACTTACCTCTACTGTTAGACTAGGCGACTCACATTTGAGGACTTTTCTCGGG
TATCTTGAGGGTTTGTGATCCTGAACCCTTAAACAGTGCTTTTTTGTTACACAGGAGGGCTTTTTTGGGGGGATGACCAGTACAGACATG
CCAGTTAGTTTTACTAGTGGGATCCCAAATCCAAAGCAGTGTAGTGGTGATTGGTCAGTGACTAACCAGGCAGCTAAGAAGTCTTAGGCA
GCAGCCCAGACATGTATAGAGGGGCAGTTAGAGGGAGAACAGGGGTGGGAAAGGGAGCAAGGGGCAGATAGCTCAGCAAGGAAAGAATGG
GCTCAGAAAAAGGAGGGCTGGCTGGAGGAGTGAGGGGCAGCTTAAGTTTGGGGAGGGTAGAAACGCCGTTTCCTTGGGAACTGGAGTGCA
GTATGAGCTGGGTGTCACTTGGCTCTGAACATACTGGCTTTGCTGTAATGCTTGAAAAGGCGTTGGTATCTTCATTTTACAGTTCATTAA
CCCAAGTACGTTTTCTTATTTAAATGACAACTTTGGTGCTTTAAAATGAGGTACCACTTTTTAAAGCTAGCTGTGTCGAGTTAAAGAAAA
AATCAGCAGTTTTTTCTCCCAGAAATGTAATTGCCAAACACTATTCATCCCCATCTTAAGTTTTACAAGGTGATGTAATCAGCTTGTTGT
AGTGATGCTGGCCAAATGGTGCTCAGCAGGTGAGAACAAAAAAACCCCAGATCTCAGTGAACTAATACACAGCTTGAGCGTTTCCATGTG
CTAATGTTGCACACTTACTAAAAAACTTTGGAAATGGAAAATAATGTATTAGTGCAACAGTTGATGTGCTTCTTTGGGCAAAGATATAGT
TTTGTTCCACAATTTGTACTTAAAAGCGAAAGAACATTGAAAACATAGACTTACTGGCTGTAGCAATGCTGGCCTGTTAACTGATAACTA
GAACTTAGGTTCACGTTTATGTAAAGTGTGTAAAACCTAGTAGAGCTTGCATAGTCGGCACTCAGTAAATGTTTGGTTCCTTTTGCCCCT
TGGTAAGTTTATTTTACCATCCTCCCACCTGCCATTCTGACTTTATTAAATCAACATGTGGACCAGAGTGTTAATGAGATGTTATTGCAG
AAGAGATTGAGAAAATTGGTATATCATGCAGATAACATACAAAATCTTTTTGTAACGTAAAAAATGCAGTTTTATTATTGCTTGTGCCTC

>6490_6490_2_ARID4B-TOMM20_ARID4B_chr1_235490228_ENST00000349213_TOMM20_chr1_235285687_ENST00000366607_length(amino acids)=153AA_BP=
MPVSRVRSEELGRRSGGRLLSFILPPPRPPPGPLPGGSCRGSIAAVLWRAARLGARTSSPGGIFRRPPPPNQGARAAAKQRYQSPPREEE

--------------------------------------------------------------
>6490_6490_3_ARID4B-TOMM20_ARID4B_chr1_235490228_ENST00000366603_TOMM20_chr1_235285687_ENST00000366607_length(transcript)=3428nt_BP=383nt
GGCGGGGCCAGATGTTGATCTCGCTCCCACTTGTCGGGTCTGAGCCCGGAACGGGACGTGGGCAGGGGCTCTGTGGCGGGCCGGTCCTGC
CCGCGGCCCACAGGCCCTCCTGGCCCCTCGGTGGCCCCCGGCCGGCCTCTCGCTCGGACGCGGCGCGTGGGGGCGCGGATTCGCTCGGCC
GGGCGCCGAGGCCCTAGGGGAGAGCGGCCGGCCCTGCGCCGGACGCCGGGCTTGTTGTGAGTTTCTTCTCTGACAGAAATGGCGTCATTG
TCGTAGACGGGAAACTCCGTCGGGTCTCGACAATGGGGACGGGAAGCTGCCGAGCTGTGTGCAGCTGAACCTGGTGTTTTAGAGGATACC
TTGGTCCCAGAGTCATCATGAAGGAAGAAAGAAACAGAAGCTTGCCAAGGAGAGAGCTGGGCTTTCCAAGTTACCTGACCTTAAAGATGC
TGAAGCTGTTCAGAAGTTCTTCCTTGAAGAAATACAGCTTGGTGAAGAGTTACTAGCTCAAGGTGAATATGAGAAGGGCGTAGACCATCT
GACAAATGCAATTGCTGTGTGTGGACAGCCACAGCAGTTACTGCAGGTCTTACAGCAAACTCTTCCACCACCAGTGTTCCAGATGCTTCT
GACTAAGCTCCCAACAATTAGTCAGAGAATTGTAAGTGCTCAGAGCTTGGCTGAAGATGATGTGGAATGAGAAACAAATGTCAACATAAT
AAAATCTCAGTTAAAAATATTTTAAAAATTCTTGGTAGTTGAGCAGCTCTGGGGGAATAAGGGCAAATATGCTTGTTATGAACTACACTG
AAATCTACCAAAGTTAATGTTTACTTTGTGTAGATCCATTTGTCTATTTTATTTATTTTTCCCAGTGAAAAGTGTATTTTGATAGAGAAC
TTTTCATTCTATAAATACACTATGAGTTACTAAAATATCATGGATTTTGTTTATTCCTGAAACATAGTTACATAGTTAAACTGTACATAT
GACATGGCTTATGTTAAAAATACCCAGTGCTCAGTTTTGAAAGATAGGCAAAAAAAAAAAAGTATAGGAGAAACTGAAGAATGTACACTT
TTTTAGAGGGCACATTTTGCTGTAAATCTGGAAATTTGATAGACTTGACTGTGTTTGTGAAAACTGAGCATTAAAGGTTTTGATTGATCC
TTTCTTTCCATTTAATCTCTGAGACGTAAATATGTGAGGTGTGCTGCTGTGCTGGGTTAACAGCTTCCTTCCCTTTCTGTGTAGCAGTCT
TGAAATGTTCTGTTTAAATCAGTAGGCTTAATGTGTTCTGGGTATTTATCTCCTTGTATTTTAAATATATGTAGTTGCAAATAGCACCAG
GAATTAGATTTCTGTACACCCCTAATCTAGCCTTGTGAGCTTCGCTAGTTAATGTGTGCTCACTTTCCCTCCATTTGTTACGTGAGAGAA
TGCGTCTGCTGATCACTGAAGTGTCCCTTTTAGCTTCTGATTCATTGGGTTCTGTTGGGCATCTTTAAATCCACCTTAACCTGAGGAATG
TATGTGGGCAACCAGGCCCTGCATTTTTTTATATTCTGAATTTTGCATGCTTGCCTGACTTAGTATTTCTGAATTGATGTTTTTTTTAAT
GGTATAACTATCTTGATTTTCACTGAAATTATATGGTTCTGTCACTACTCTGTAAATTAATCCGAAACTTTTAAGGTAACTGGGATGATC
TGCTTGTAAAAATGCTTGTTGCCTTTTGCTTTATCTTCAGTGTACCTCCTTAATCCTGCTTCAACTTGATTATCTTGTGAAACGATGAGA
GTAAGTTGCAACCTTGTGACTGAAAACTTGAAAAGAGTGGAGCAGGTGGGACCTCTTATTCTCAAATAGTGACATATTCTCCGTAGTCAC
AGTTTCAGAACTGAGTAAGGATCCTTGGTACTTGGTGGCATCTGTTGAACTGAGGAGCATTTCTCATTGTAAAGATTGCCTTTGTTCTGT
CTAAAAGTCTGGAGAAATCCCAAAGACTTTTCCTATGTACTAGGCATTTTATTTTGATTGACTTACAAACTCTTCTTAATCATTATCAAT
CTCGGTTTTTTTGTGGTGCAGTGGAAGGAGAAATAGGTCTAGTTTCTGCCTCTGATTAGCCGCACAGCCTTGAACAAATCACATTTCATC
TTTGAACTTACCTCTACTGTTAGACTAGGCGACTCACATTTGAGGACTTTTCTCGGGTATCTTGAGGGTTTGTGATCCTGAACCCTTAAA
CAGTGCTTTTTTGTTACACAGGAGGGCTTTTTTGGGGGGATGACCAGTACAGACATGCCAGTTAGTTTTACTAGTGGGATCCCAAATCCA
AAGCAGTGTAGTGGTGATTGGTCAGTGACTAACCAGGCAGCTAAGAAGTCTTAGGCAGCAGCCCAGACATGTATAGAGGGGCAGTTAGAG
GGAGAACAGGGGTGGGAAAGGGAGCAAGGGGCAGATAGCTCAGCAAGGAAAGAATGGGCTCAGAAAAAGGAGGGCTGGCTGGAGGAGTGA
GGGGCAGCTTAAGTTTGGGGAGGGTAGAAACGCCGTTTCCTTGGGAACTGGAGTGCAGTATGAGCTGGGTGTCACTTGGCTCTGAACATA
CTGGCTTTGCTGTAATGCTTGAAAAGGCGTTGGTATCTTCATTTTACAGTTCATTAACCCAAGTACGTTTTCTTATTTAAATGACAACTT
TGGTGCTTTAAAATGAGGTACCACTTTTTAAAGCTAGCTGTGTCGAGTTAAAGAAAAAATCAGCAGTTTTTTCTCCCAGAAATGTAATTG
CCAAACACTATTCATCCCCATCTTAAGTTTTACAAGGTGATGTAATCAGCTTGTTGTAGTGATGCTGGCCAAATGGTGCTCAGCAGGTGA
GAACAAAAAAACCCCAGATCTCAGTGAACTAATACACAGCTTGAGCGTTTCCATGTGCTAATGTTGCACACTTACTAAAAAACTTTGGAA
ATGGAAAATAATGTATTAGTGCAACAGTTGATGTGCTTCTTTGGGCAAAGATATAGTTTTGTTCCACAATTTGTACTTAAAAGCGAAAGA
ACATTGAAAACATAGACTTACTGGCTGTAGCAATGCTGGCCTGTTAACTGATAACTAGAACTTAGGTTCACGTTTATGTAAAGTGTGTAA
AACCTAGTAGAGCTTGCATAGTCGGCACTCAGTAAATGTTTGGTTCCTTTTGCCCCTTGGTAAGTTTATTTTACCATCCTCCCACCTGCC
ATTCTGACTTTATTAAATCAACATGTGGACCAGAGTGTTAATGAGATGTTATTGCAGAAGAGATTGAGAAAATTGGTATATCATGCAGAT
AACATACAAAATCTTTTTGTAACGTAAAAAATGCAGTTTTATTATTGCTTGTGCCTCAACTGTTTAAGTGAATATTAAAGGGCTTGGAGA

>6490_6490_3_ARID4B-TOMM20_ARID4B_chr1_235490228_ENST00000366603_TOMM20_chr1_235285687_ENST00000366607_length(amino acids)=69AA_BP=

--------------------------------------------------------------
>6490_6490_4_ARID4B-TOMM20_ARID4B_chr1_235490229_ENST00000264183_TOMM20_chr1_235285687_ENST00000366607_length(transcript)=3549nt_BP=504nt
AAAGGGGGGGAACCTAGAGTCGGTGGGGGGGAAGCGATGTTTGCCCGTCAGTCGAGTCCGGAGTGAGGAGCTCGGTCGCCGAAGCGGAGG
GAGACTCTTGAGCTTCATCTTGCCGCCGCCACGGCCACCGCCTGGACCTTTGCCCGGAGGGAGCTGCAGAGGGTCCATCGCCGCCGTCCT
CTGGAGGGCAGCGCGATTGGGGGCCCGGACCTCCAGTCCGGGGGGGATTTTTCGTCGTCCCCCTCCCCCCAACCAGGGAGCCCGAGCGGC
CGCCAAACAAAGGTACCAGTCGCCGCCGCGGGAGGAGGAGGAGCCGGAGCCTCTGCCTCAGCAGCCGCTGGACCCGCCGCCCTTCTTCCC
CATCTCTCCCCCGGGCCTGCTGGTTTTGGGGGGGAGAAGGAGAGAGGGGACTCTGGACGTGCCAGGGTCAGATCTCGCCTCCGAGGAAGG
TGCAGCTGAACCTGGTGTTTTAGAGGATACCTTGGTCCCAGAGTCATCATGAAGGAAGAAAGAAACAGAAGCTTGCCAAGGAGAGAGCTG
GGCTTTCCAAGTTACCTGACCTTAAAGATGCTGAAGCTGTTCAGAAGTTCTTCCTTGAAGAAATACAGCTTGGTGAAGAGTTACTAGCTC
AAGGTGAATATGAGAAGGGCGTAGACCATCTGACAAATGCAATTGCTGTGTGTGGACAGCCACAGCAGTTACTGCAGGTCTTACAGCAAA
CTCTTCCACCACCAGTGTTCCAGATGCTTCTGACTAAGCTCCCAACAATTAGTCAGAGAATTGTAAGTGCTCAGAGCTTGGCTGAAGATG
ATGTGGAATGAGAAACAAATGTCAACATAATAAAATCTCAGTTAAAAATATTTTAAAAATTCTTGGTAGTTGAGCAGCTCTGGGGGAATA
AGGGCAAATATGCTTGTTATGAACTACACTGAAATCTACCAAAGTTAATGTTTACTTTGTGTAGATCCATTTGTCTATTTTATTTATTTT
TCCCAGTGAAAAGTGTATTTTGATAGAGAACTTTTCATTCTATAAATACACTATGAGTTACTAAAATATCATGGATTTTGTTTATTCCTG
AAACATAGTTACATAGTTAAACTGTACATATGACATGGCTTATGTTAAAAATACCCAGTGCTCAGTTTTGAAAGATAGGCAAAAAAAAAA
AAGTATAGGAGAAACTGAAGAATGTACACTTTTTTAGAGGGCACATTTTGCTGTAAATCTGGAAATTTGATAGACTTGACTGTGTTTGTG
AAAACTGAGCATTAAAGGTTTTGATTGATCCTTTCTTTCCATTTAATCTCTGAGACGTAAATATGTGAGGTGTGCTGCTGTGCTGGGTTA
ACAGCTTCCTTCCCTTTCTGTGTAGCAGTCTTGAAATGTTCTGTTTAAATCAGTAGGCTTAATGTGTTCTGGGTATTTATCTCCTTGTAT
TTTAAATATATGTAGTTGCAAATAGCACCAGGAATTAGATTTCTGTACACCCCTAATCTAGCCTTGTGAGCTTCGCTAGTTAATGTGTGC
TCACTTTCCCTCCATTTGTTACGTGAGAGAATGCGTCTGCTGATCACTGAAGTGTCCCTTTTAGCTTCTGATTCATTGGGTTCTGTTGGG
CATCTTTAAATCCACCTTAACCTGAGGAATGTATGTGGGCAACCAGGCCCTGCATTTTTTTATATTCTGAATTTTGCATGCTTGCCTGAC
TTAGTATTTCTGAATTGATGTTTTTTTTAATGGTATAACTATCTTGATTTTCACTGAAATTATATGGTTCTGTCACTACTCTGTAAATTA
ATCCGAAACTTTTAAGGTAACTGGGATGATCTGCTTGTAAAAATGCTTGTTGCCTTTTGCTTTATCTTCAGTGTACCTCCTTAATCCTGC
TTCAACTTGATTATCTTGTGAAACGATGAGAGTAAGTTGCAACCTTGTGACTGAAAACTTGAAAAGAGTGGAGCAGGTGGGACCTCTTAT
TCTCAAATAGTGACATATTCTCCGTAGTCACAGTTTCAGAACTGAGTAAGGATCCTTGGTACTTGGTGGCATCTGTTGAACTGAGGAGCA
TTTCTCATTGTAAAGATTGCCTTTGTTCTGTCTAAAAGTCTGGAGAAATCCCAAAGACTTTTCCTATGTACTAGGCATTTTATTTTGATT
GACTTACAAACTCTTCTTAATCATTATCAATCTCGGTTTTTTTGTGGTGCAGTGGAAGGAGAAATAGGTCTAGTTTCTGCCTCTGATTAG
CCGCACAGCCTTGAACAAATCACATTTCATCTTTGAACTTACCTCTACTGTTAGACTAGGCGACTCACATTTGAGGACTTTTCTCGGGTA
TCTTGAGGGTTTGTGATCCTGAACCCTTAAACAGTGCTTTTTTGTTACACAGGAGGGCTTTTTTGGGGGGATGACCAGTACAGACATGCC
AGTTAGTTTTACTAGTGGGATCCCAAATCCAAAGCAGTGTAGTGGTGATTGGTCAGTGACTAACCAGGCAGCTAAGAAGTCTTAGGCAGC
AGCCCAGACATGTATAGAGGGGCAGTTAGAGGGAGAACAGGGGTGGGAAAGGGAGCAAGGGGCAGATAGCTCAGCAAGGAAAGAATGGGC
TCAGAAAAAGGAGGGCTGGCTGGAGGAGTGAGGGGCAGCTTAAGTTTGGGGAGGGTAGAAACGCCGTTTCCTTGGGAACTGGAGTGCAGT
ATGAGCTGGGTGTCACTTGGCTCTGAACATACTGGCTTTGCTGTAATGCTTGAAAAGGCGTTGGTATCTTCATTTTACAGTTCATTAACC
CAAGTACGTTTTCTTATTTAAATGACAACTTTGGTGCTTTAAAATGAGGTACCACTTTTTAAAGCTAGCTGTGTCGAGTTAAAGAAAAAA
TCAGCAGTTTTTTCTCCCAGAAATGTAATTGCCAAACACTATTCATCCCCATCTTAAGTTTTACAAGGTGATGTAATCAGCTTGTTGTAG
TGATGCTGGCCAAATGGTGCTCAGCAGGTGAGAACAAAAAAACCCCAGATCTCAGTGAACTAATACACAGCTTGAGCGTTTCCATGTGCT
AATGTTGCACACTTACTAAAAAACTTTGGAAATGGAAAATAATGTATTAGTGCAACAGTTGATGTGCTTCTTTGGGCAAAGATATAGTTT
TGTTCCACAATTTGTACTTAAAAGCGAAAGAACATTGAAAACATAGACTTACTGGCTGTAGCAATGCTGGCCTGTTAACTGATAACTAGA
ACTTAGGTTCACGTTTATGTAAAGTGTGTAAAACCTAGTAGAGCTTGCATAGTCGGCACTCAGTAAATGTTTGGTTCCTTTTGCCCCTTG
GTAAGTTTATTTTACCATCCTCCCACCTGCCATTCTGACTTTATTAAATCAACATGTGGACCAGAGTGTTAATGAGATGTTATTGCAGAA
GAGATTGAGAAAATTGGTATATCATGCAGATAACATACAAAATCTTTTTGTAACGTAAAAAATGCAGTTTTATTATTGCTTGTGCCTCAA

>6490_6490_4_ARID4B-TOMM20_ARID4B_chr1_235490229_ENST00000264183_TOMM20_chr1_235285687_ENST00000366607_length(amino acids)=153AA_BP=
MPVSRVRSEELGRRSGGRLLSFILPPPRPPPGPLPGGSCRGSIAAVLWRAARLGARTSSPGGIFRRPPPPNQGARAAAKQRYQSPPREEE

--------------------------------------------------------------
>6490_6490_5_ARID4B-TOMM20_ARID4B_chr1_235490229_ENST00000349213_TOMM20_chr1_235285687_ENST00000366607_length(transcript)=3551nt_BP=506nt
AGAAAGGGGGGGAACCTAGAGTCGGTGGGGGGGAAGCGATGTTTGCCCGTCAGTCGAGTCCGGAGTGAGGAGCTCGGTCGCCGAAGCGGA
GGGAGACTCTTGAGCTTCATCTTGCCGCCGCCACGGCCACCGCCTGGACCTTTGCCCGGAGGGAGCTGCAGAGGGTCCATCGCCGCCGTC
CTCTGGAGGGCAGCGCGATTGGGGGCCCGGACCTCCAGTCCGGGGGGGATTTTTCGTCGTCCCCCTCCCCCCAACCAGGGAGCCCGAGCG
GCCGCCAAACAAAGGTACCAGTCGCCGCCGCGGGAGGAGGAGGAGCCGGAGCCTCTGCCTCAGCAGCCGCTGGACCCGCCGCCCTTCTTC
CCCATCTCTCCCCCGGGCCTGCTGGTTTTGGGGGGGAGAAGGAGAGAGGGGACTCTGGACGTGCCAGGGTCAGATCTCGCCTCCGAGGAA
GGTGCAGCTGAACCTGGTGTTTTAGAGGATACCTTGGTCCCAGAGTCATCATGAAGGAAGAAAGAAACAGAAGCTTGCCAAGGAGAGAGC
TGGGCTTTCCAAGTTACCTGACCTTAAAGATGCTGAAGCTGTTCAGAAGTTCTTCCTTGAAGAAATACAGCTTGGTGAAGAGTTACTAGC
TCAAGGTGAATATGAGAAGGGCGTAGACCATCTGACAAATGCAATTGCTGTGTGTGGACAGCCACAGCAGTTACTGCAGGTCTTACAGCA
AACTCTTCCACCACCAGTGTTCCAGATGCTTCTGACTAAGCTCCCAACAATTAGTCAGAGAATTGTAAGTGCTCAGAGCTTGGCTGAAGA
TGATGTGGAATGAGAAACAAATGTCAACATAATAAAATCTCAGTTAAAAATATTTTAAAAATTCTTGGTAGTTGAGCAGCTCTGGGGGAA
TAAGGGCAAATATGCTTGTTATGAACTACACTGAAATCTACCAAAGTTAATGTTTACTTTGTGTAGATCCATTTGTCTATTTTATTTATT
TTTCCCAGTGAAAAGTGTATTTTGATAGAGAACTTTTCATTCTATAAATACACTATGAGTTACTAAAATATCATGGATTTTGTTTATTCC
TGAAACATAGTTACATAGTTAAACTGTACATATGACATGGCTTATGTTAAAAATACCCAGTGCTCAGTTTTGAAAGATAGGCAAAAAAAA
AAAAGTATAGGAGAAACTGAAGAATGTACACTTTTTTAGAGGGCACATTTTGCTGTAAATCTGGAAATTTGATAGACTTGACTGTGTTTG
TGAAAACTGAGCATTAAAGGTTTTGATTGATCCTTTCTTTCCATTTAATCTCTGAGACGTAAATATGTGAGGTGTGCTGCTGTGCTGGGT
TAACAGCTTCCTTCCCTTTCTGTGTAGCAGTCTTGAAATGTTCTGTTTAAATCAGTAGGCTTAATGTGTTCTGGGTATTTATCTCCTTGT
ATTTTAAATATATGTAGTTGCAAATAGCACCAGGAATTAGATTTCTGTACACCCCTAATCTAGCCTTGTGAGCTTCGCTAGTTAATGTGT
GCTCACTTTCCCTCCATTTGTTACGTGAGAGAATGCGTCTGCTGATCACTGAAGTGTCCCTTTTAGCTTCTGATTCATTGGGTTCTGTTG
GGCATCTTTAAATCCACCTTAACCTGAGGAATGTATGTGGGCAACCAGGCCCTGCATTTTTTTATATTCTGAATTTTGCATGCTTGCCTG
ACTTAGTATTTCTGAATTGATGTTTTTTTTAATGGTATAACTATCTTGATTTTCACTGAAATTATATGGTTCTGTCACTACTCTGTAAAT
TAATCCGAAACTTTTAAGGTAACTGGGATGATCTGCTTGTAAAAATGCTTGTTGCCTTTTGCTTTATCTTCAGTGTACCTCCTTAATCCT
GCTTCAACTTGATTATCTTGTGAAACGATGAGAGTAAGTTGCAACCTTGTGACTGAAAACTTGAAAAGAGTGGAGCAGGTGGGACCTCTT
ATTCTCAAATAGTGACATATTCTCCGTAGTCACAGTTTCAGAACTGAGTAAGGATCCTTGGTACTTGGTGGCATCTGTTGAACTGAGGAG
CATTTCTCATTGTAAAGATTGCCTTTGTTCTGTCTAAAAGTCTGGAGAAATCCCAAAGACTTTTCCTATGTACTAGGCATTTTATTTTGA
TTGACTTACAAACTCTTCTTAATCATTATCAATCTCGGTTTTTTTGTGGTGCAGTGGAAGGAGAAATAGGTCTAGTTTCTGCCTCTGATT
AGCCGCACAGCCTTGAACAAATCACATTTCATCTTTGAACTTACCTCTACTGTTAGACTAGGCGACTCACATTTGAGGACTTTTCTCGGG
TATCTTGAGGGTTTGTGATCCTGAACCCTTAAACAGTGCTTTTTTGTTACACAGGAGGGCTTTTTTGGGGGGATGACCAGTACAGACATG
CCAGTTAGTTTTACTAGTGGGATCCCAAATCCAAAGCAGTGTAGTGGTGATTGGTCAGTGACTAACCAGGCAGCTAAGAAGTCTTAGGCA
GCAGCCCAGACATGTATAGAGGGGCAGTTAGAGGGAGAACAGGGGTGGGAAAGGGAGCAAGGGGCAGATAGCTCAGCAAGGAAAGAATGG
GCTCAGAAAAAGGAGGGCTGGCTGGAGGAGTGAGGGGCAGCTTAAGTTTGGGGAGGGTAGAAACGCCGTTTCCTTGGGAACTGGAGTGCA
GTATGAGCTGGGTGTCACTTGGCTCTGAACATACTGGCTTTGCTGTAATGCTTGAAAAGGCGTTGGTATCTTCATTTTACAGTTCATTAA
CCCAAGTACGTTTTCTTATTTAAATGACAACTTTGGTGCTTTAAAATGAGGTACCACTTTTTAAAGCTAGCTGTGTCGAGTTAAAGAAAA
AATCAGCAGTTTTTTCTCCCAGAAATGTAATTGCCAAACACTATTCATCCCCATCTTAAGTTTTACAAGGTGATGTAATCAGCTTGTTGT
AGTGATGCTGGCCAAATGGTGCTCAGCAGGTGAGAACAAAAAAACCCCAGATCTCAGTGAACTAATACACAGCTTGAGCGTTTCCATGTG
CTAATGTTGCACACTTACTAAAAAACTTTGGAAATGGAAAATAATGTATTAGTGCAACAGTTGATGTGCTTCTTTGGGCAAAGATATAGT
TTTGTTCCACAATTTGTACTTAAAAGCGAAAGAACATTGAAAACATAGACTTACTGGCTGTAGCAATGCTGGCCTGTTAACTGATAACTA
GAACTTAGGTTCACGTTTATGTAAAGTGTGTAAAACCTAGTAGAGCTTGCATAGTCGGCACTCAGTAAATGTTTGGTTCCTTTTGCCCCT
TGGTAAGTTTATTTTACCATCCTCCCACCTGCCATTCTGACTTTATTAAATCAACATGTGGACCAGAGTGTTAATGAGATGTTATTGCAG
AAGAGATTGAGAAAATTGGTATATCATGCAGATAACATACAAAATCTTTTTGTAACGTAAAAAATGCAGTTTTATTATTGCTTGTGCCTC

>6490_6490_5_ARID4B-TOMM20_ARID4B_chr1_235490229_ENST00000349213_TOMM20_chr1_235285687_ENST00000366607_length(amino acids)=153AA_BP=
MPVSRVRSEELGRRSGGRLLSFILPPPRPPPGPLPGGSCRGSIAAVLWRAARLGARTSSPGGIFRRPPPPNQGARAAAKQRYQSPPREEE

--------------------------------------------------------------
>6490_6490_6_ARID4B-TOMM20_ARID4B_chr1_235490229_ENST00000366603_TOMM20_chr1_235285687_ENST00000366607_length(transcript)=3428nt_BP=383nt
GGCGGGGCCAGATGTTGATCTCGCTCCCACTTGTCGGGTCTGAGCCCGGAACGGGACGTGGGCAGGGGCTCTGTGGCGGGCCGGTCCTGC
CCGCGGCCCACAGGCCCTCCTGGCCCCTCGGTGGCCCCCGGCCGGCCTCTCGCTCGGACGCGGCGCGTGGGGGCGCGGATTCGCTCGGCC
GGGCGCCGAGGCCCTAGGGGAGAGCGGCCGGCCCTGCGCCGGACGCCGGGCTTGTTGTGAGTTTCTTCTCTGACAGAAATGGCGTCATTG
TCGTAGACGGGAAACTCCGTCGGGTCTCGACAATGGGGACGGGAAGCTGCCGAGCTGTGTGCAGCTGAACCTGGTGTTTTAGAGGATACC
TTGGTCCCAGAGTCATCATGAAGGAAGAAAGAAACAGAAGCTTGCCAAGGAGAGAGCTGGGCTTTCCAAGTTACCTGACCTTAAAGATGC
TGAAGCTGTTCAGAAGTTCTTCCTTGAAGAAATACAGCTTGGTGAAGAGTTACTAGCTCAAGGTGAATATGAGAAGGGCGTAGACCATCT
GACAAATGCAATTGCTGTGTGTGGACAGCCACAGCAGTTACTGCAGGTCTTACAGCAAACTCTTCCACCACCAGTGTTCCAGATGCTTCT
GACTAAGCTCCCAACAATTAGTCAGAGAATTGTAAGTGCTCAGAGCTTGGCTGAAGATGATGTGGAATGAGAAACAAATGTCAACATAAT
AAAATCTCAGTTAAAAATATTTTAAAAATTCTTGGTAGTTGAGCAGCTCTGGGGGAATAAGGGCAAATATGCTTGTTATGAACTACACTG
AAATCTACCAAAGTTAATGTTTACTTTGTGTAGATCCATTTGTCTATTTTATTTATTTTTCCCAGTGAAAAGTGTATTTTGATAGAGAAC
TTTTCATTCTATAAATACACTATGAGTTACTAAAATATCATGGATTTTGTTTATTCCTGAAACATAGTTACATAGTTAAACTGTACATAT
GACATGGCTTATGTTAAAAATACCCAGTGCTCAGTTTTGAAAGATAGGCAAAAAAAAAAAAGTATAGGAGAAACTGAAGAATGTACACTT
TTTTAGAGGGCACATTTTGCTGTAAATCTGGAAATTTGATAGACTTGACTGTGTTTGTGAAAACTGAGCATTAAAGGTTTTGATTGATCC
TTTCTTTCCATTTAATCTCTGAGACGTAAATATGTGAGGTGTGCTGCTGTGCTGGGTTAACAGCTTCCTTCCCTTTCTGTGTAGCAGTCT
TGAAATGTTCTGTTTAAATCAGTAGGCTTAATGTGTTCTGGGTATTTATCTCCTTGTATTTTAAATATATGTAGTTGCAAATAGCACCAG
GAATTAGATTTCTGTACACCCCTAATCTAGCCTTGTGAGCTTCGCTAGTTAATGTGTGCTCACTTTCCCTCCATTTGTTACGTGAGAGAA
TGCGTCTGCTGATCACTGAAGTGTCCCTTTTAGCTTCTGATTCATTGGGTTCTGTTGGGCATCTTTAAATCCACCTTAACCTGAGGAATG
TATGTGGGCAACCAGGCCCTGCATTTTTTTATATTCTGAATTTTGCATGCTTGCCTGACTTAGTATTTCTGAATTGATGTTTTTTTTAAT
GGTATAACTATCTTGATTTTCACTGAAATTATATGGTTCTGTCACTACTCTGTAAATTAATCCGAAACTTTTAAGGTAACTGGGATGATC
TGCTTGTAAAAATGCTTGTTGCCTTTTGCTTTATCTTCAGTGTACCTCCTTAATCCTGCTTCAACTTGATTATCTTGTGAAACGATGAGA
GTAAGTTGCAACCTTGTGACTGAAAACTTGAAAAGAGTGGAGCAGGTGGGACCTCTTATTCTCAAATAGTGACATATTCTCCGTAGTCAC
AGTTTCAGAACTGAGTAAGGATCCTTGGTACTTGGTGGCATCTGTTGAACTGAGGAGCATTTCTCATTGTAAAGATTGCCTTTGTTCTGT
CTAAAAGTCTGGAGAAATCCCAAAGACTTTTCCTATGTACTAGGCATTTTATTTTGATTGACTTACAAACTCTTCTTAATCATTATCAAT
CTCGGTTTTTTTGTGGTGCAGTGGAAGGAGAAATAGGTCTAGTTTCTGCCTCTGATTAGCCGCACAGCCTTGAACAAATCACATTTCATC
TTTGAACTTACCTCTACTGTTAGACTAGGCGACTCACATTTGAGGACTTTTCTCGGGTATCTTGAGGGTTTGTGATCCTGAACCCTTAAA
CAGTGCTTTTTTGTTACACAGGAGGGCTTTTTTGGGGGGATGACCAGTACAGACATGCCAGTTAGTTTTACTAGTGGGATCCCAAATCCA
AAGCAGTGTAGTGGTGATTGGTCAGTGACTAACCAGGCAGCTAAGAAGTCTTAGGCAGCAGCCCAGACATGTATAGAGGGGCAGTTAGAG
GGAGAACAGGGGTGGGAAAGGGAGCAAGGGGCAGATAGCTCAGCAAGGAAAGAATGGGCTCAGAAAAAGGAGGGCTGGCTGGAGGAGTGA
GGGGCAGCTTAAGTTTGGGGAGGGTAGAAACGCCGTTTCCTTGGGAACTGGAGTGCAGTATGAGCTGGGTGTCACTTGGCTCTGAACATA
CTGGCTTTGCTGTAATGCTTGAAAAGGCGTTGGTATCTTCATTTTACAGTTCATTAACCCAAGTACGTTTTCTTATTTAAATGACAACTT
TGGTGCTTTAAAATGAGGTACCACTTTTTAAAGCTAGCTGTGTCGAGTTAAAGAAAAAATCAGCAGTTTTTTCTCCCAGAAATGTAATTG
CCAAACACTATTCATCCCCATCTTAAGTTTTACAAGGTGATGTAATCAGCTTGTTGTAGTGATGCTGGCCAAATGGTGCTCAGCAGGTGA
GAACAAAAAAACCCCAGATCTCAGTGAACTAATACACAGCTTGAGCGTTTCCATGTGCTAATGTTGCACACTTACTAAAAAACTTTGGAA
ATGGAAAATAATGTATTAGTGCAACAGTTGATGTGCTTCTTTGGGCAAAGATATAGTTTTGTTCCACAATTTGTACTTAAAAGCGAAAGA
ACATTGAAAACATAGACTTACTGGCTGTAGCAATGCTGGCCTGTTAACTGATAACTAGAACTTAGGTTCACGTTTATGTAAAGTGTGTAA
AACCTAGTAGAGCTTGCATAGTCGGCACTCAGTAAATGTTTGGTTCCTTTTGCCCCTTGGTAAGTTTATTTTACCATCCTCCCACCTGCC
ATTCTGACTTTATTAAATCAACATGTGGACCAGAGTGTTAATGAGATGTTATTGCAGAAGAGATTGAGAAAATTGGTATATCATGCAGAT
AACATACAAAATCTTTTTGTAACGTAAAAAATGCAGTTTTATTATTGCTTGTGCCTCAACTGTTTAAGTGAATATTAAAGGGCTTGGAGA

>6490_6490_6_ARID4B-TOMM20_ARID4B_chr1_235490229_ENST00000366603_TOMM20_chr1_235285687_ENST00000366607_length(amino acids)=69AA_BP=

--------------------------------------------------------------

Top

Fusion Gene PPI Analysis for ARID4B-TOMM20


check button Go to ChiPPI (Chimeric Protein-Protein interactions) to see the chimeric PPI interaction in

ChiPPI page.


check button Protein-protein interactors with each fusion partner protein in wild-type (BIOGRID-3.4.160)
HgeneHgene's interactorsTgeneTgene's interactors


check button - Retained PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenStill interaction with


check button - Lost PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


check button - Retained PPIs, but lost function due to frame-shift fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


Top

Related Drugs for ARID4B-TOMM20


check button Drugs targeting genes involved in this fusion gene.
(DrugBank Version 5.1.8 2021-05-08)
PartnerGeneUniProtAccDrugBank IDDrug nameDrug activityDrug typeDrug status

Top

Related Diseases for ARID4B-TOMM20


check button Diseases associated with fusion partners.
(DisGeNet 4.0)
PartnerGeneDisease IDDisease name# pubmedsSource