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Center for Computational Systems Medicine
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Fusion Gene Summary

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Fusion Gene ORF analysis

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Fusion Genomic Features

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Fusion Protein Features

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Fusion Gene Sequence

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Fusion Gene PPI analysis

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Related Drugs

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Related Diseases

Fusion gene:PICALM-ME3 (FusionGDB2 ID:65153)

Fusion Gene Summary for PICALM-ME3

check button Fusion gene summary
Fusion gene informationFusion gene name: PICALM-ME3
Fusion gene ID: 65153
HgeneTgene
Gene symbol

PICALM

ME3

Gene ID

8301

56110

Gene namephosphatidylinositol binding clathrin assembly proteinprotocadherin gamma subfamily A, 5
SynonymsCALM|CLTH|LAPCDH-GAMMA-A5|ME3|PCDH-GAMMA-A5
Cytomap

11q14.2

5q31.3

Type of geneprotein-codingprotein-coding
Descriptionphosphatidylinositol-binding clathrin assembly proteinclathrin assembly lymphoid myeloid leukemia proteinprotocadherin gamma-A5cadherin ME3
Modification date2020032220200313
UniProtAcc.

Q16798

Ensembl transtripts involved in fusion geneENST00000356360, ENST00000393346, 
ENST00000526033, ENST00000528398, 
ENST00000532317, ENST00000528411, 
ENST00000525957, ENST00000323418, 
ENST00000359636, ENST00000393324, 
ENST00000543262, 
Fusion gene scores* DoF score24 X 29 X 9=62649 X 9 X 4=324
# samples 3911
** MAII scorelog2(39/6264*10)=-4.00553818354143
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0		log2(11/324*10)=-1.55849028935997
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0
Context

PubMed: PICALM [Title/Abstract] AND ME3 [Title/Abstract] AND fusion [Title/Abstract]

Most frequent breakpointPICALM(85707869)-ME3(86198482), # samples:3
Anticipated loss of major functional domain due to fusion event.PICALM-ME3 seems lost the major protein functional domain in Hgene partner, which is a CGC due to the frame-shifted ORF.
PICALM-ME3 seems lost the major protein functional domain in Hgene partner, which is a essential gene due to the frame-shifted ORF.
PICALM-ME3 seems lost the major protein functional domain in Tgene partner, which is a cell metabolism gene due to the frame-shifted ORF.
PICALM-ME3 seems lost the major protein functional domain in Tgene partner, which is a essential gene due to the frame-shifted ORF.
* DoF score (Degree of Frequency) = # partners X # break points X # cancer types
** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10)

check button Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez
PartnerGeneGO IDGO termPubMed ID
HgenePICALM

GO:0006897

endocytosis

22118466

HgenePICALM

GO:0006898

receptor-mediated endocytosis

10436022

HgenePICALM

GO:0032880

regulation of protein localization

10436022

HgenePICALM

GO:0045893

positive regulation of transcription, DNA-templated

11425879

HgenePICALM

GO:0048261

negative regulation of receptor-mediated endocytosis

10436022

HgenePICALM

GO:1905224

clathrin-coated pit assembly

16262731


check buttonFusion gene breakpoints across PICALM (5'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.
all structure

check buttonFusion gene breakpoints across ME3 (3'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.
all structure

check button Fusion gene information from two resources (ChiTars 5.0 and ChimerDB 4.0)
* All genome coordinats were lifted-over on hg19.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
SourceDiseaseSampleHgeneHchrHbpHstrandTgeneTchrTbpTstrand
ChimerDB4OVTCGA-20-0987-01APICALMchr11

85779693

-ME3chr11

86270865

-
ChimerDB4OVTCGA-VG-A8LO-01APICALMchr11

85707869

-ME3chr11

86176242

-
ChimerDB4OVTCGA-VG-A8LO-01APICALMchr11

85707869

-ME3chr11

86198482

-
ChimerDB4OVTCGA-VG-A8LOPICALMchr11

85701292

-ME3chr11

86198482

-
ChimerDB4OVTCGA-VG-A8LOPICALMchr11

85707868

-ME3chr11

86176242

-
ChimerDB4OVTCGA-VG-A8LOPICALMchr11

85707868

-ME3chr11

86198482

-


Top

Fusion Gene ORF analysis for PICALM-ME3

check button Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
ORFHenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrand
5CDS-5UTRENST00000356360ENST00000525957PICALMchr11

85707869

-ME3chr11

86176242

-
5CDS-5UTRENST00000356360ENST00000525957PICALMchr11

85707869

-ME3chr11

86198482

-
5CDS-5UTRENST00000356360ENST00000525957PICALMchr11

85701292

-ME3chr11

86198482

-
5CDS-5UTRENST00000356360ENST00000525957PICALMchr11

85707868

-ME3chr11

86176242

-
5CDS-5UTRENST00000356360ENST00000525957PICALMchr11

85707868

-ME3chr11

86198482

-
5CDS-5UTRENST00000393346ENST00000525957PICALMchr11

85707869

-ME3chr11

86176242

-
5CDS-5UTRENST00000393346ENST00000525957PICALMchr11

85707869

-ME3chr11

86198482

-
5CDS-5UTRENST00000393346ENST00000525957PICALMchr11

85701292

-ME3chr11

86198482

-
5CDS-5UTRENST00000393346ENST00000525957PICALMchr11

85707868

-ME3chr11

86176242

-
5CDS-5UTRENST00000393346ENST00000525957PICALMchr11

85707868

-ME3chr11

86198482

-
5CDS-5UTRENST00000526033ENST00000525957PICALMchr11

85707869

-ME3chr11

86176242

-
5CDS-5UTRENST00000526033ENST00000525957PICALMchr11

85707869

-ME3chr11

86198482

-
5CDS-5UTRENST00000526033ENST00000525957PICALMchr11

85701292

-ME3chr11

86198482

-
5CDS-5UTRENST00000526033ENST00000525957PICALMchr11

85707868

-ME3chr11

86176242

-
5CDS-5UTRENST00000526033ENST00000525957PICALMchr11

85707868

-ME3chr11

86198482

-
5CDS-5UTRENST00000528398ENST00000525957PICALMchr11

85707869

-ME3chr11

86176242

-
5CDS-5UTRENST00000528398ENST00000525957PICALMchr11

85707869

-ME3chr11

86198482

-
5CDS-5UTRENST00000528398ENST00000525957PICALMchr11

85707868

-ME3chr11

86176242

-
5CDS-5UTRENST00000528398ENST00000525957PICALMchr11

85707868

-ME3chr11

86198482

-
5CDS-5UTRENST00000532317ENST00000525957PICALMchr11

85707869

-ME3chr11

86176242

-
5CDS-5UTRENST00000532317ENST00000525957PICALMchr11

85707869

-ME3chr11

86198482

-
5CDS-5UTRENST00000532317ENST00000525957PICALMchr11

85707868

-ME3chr11

86176242

-
5CDS-5UTRENST00000532317ENST00000525957PICALMchr11

85707868

-ME3chr11

86198482

-
5CDS-intronENST00000356360ENST00000525957PICALMchr11

85779693

-ME3chr11

86270865

-
5CDS-intronENST00000393346ENST00000525957PICALMchr11

85779693

-ME3chr11

86270865

-
5CDS-intronENST00000526033ENST00000525957PICALMchr11

85779693

-ME3chr11

86270865

-
5CDS-intronENST00000532317ENST00000525957PICALMchr11

85779693

-ME3chr11

86270865

-
5UTR-3CDSENST00000528411ENST00000323418PICALMchr11

85779693

-ME3chr11

86270865

-
5UTR-3CDSENST00000528411ENST00000359636PICALMchr11

85779693

-ME3chr11

86270865

-
5UTR-3CDSENST00000528411ENST00000393324PICALMchr11

85779693

-ME3chr11

86270865

-
5UTR-3CDSENST00000528411ENST00000543262PICALMchr11

85779693

-ME3chr11

86270865

-
5UTR-intronENST00000528411ENST00000525957PICALMchr11

85779693

-ME3chr11

86270865

-
Frame-shiftENST00000356360ENST00000323418PICALMchr11

85707869

-ME3chr11

86176242

-
Frame-shiftENST00000356360ENST00000323418PICALMchr11

85707869

-ME3chr11

86198482

-
Frame-shiftENST00000356360ENST00000323418PICALMchr11

85701292

-ME3chr11

86198482

-
Frame-shiftENST00000356360ENST00000323418PICALMchr11

85707868

-ME3chr11

86176242

-
Frame-shiftENST00000356360ENST00000323418PICALMchr11

85707868

-ME3chr11

86198482

-
Frame-shiftENST00000356360ENST00000359636PICALMchr11

85707869

-ME3chr11

86176242

-
Frame-shiftENST00000356360ENST00000359636PICALMchr11

85707869

-ME3chr11

86198482

-
Frame-shiftENST00000356360ENST00000359636PICALMchr11

85701292

-ME3chr11

86198482

-
Frame-shiftENST00000356360ENST00000359636PICALMchr11

85707868

-ME3chr11

86176242

-
Frame-shiftENST00000356360ENST00000359636PICALMchr11

85707868

-ME3chr11

86198482

-
Frame-shiftENST00000356360ENST00000393324PICALMchr11

85707869

-ME3chr11

86176242

-
Frame-shiftENST00000356360ENST00000393324PICALMchr11

85707869

-ME3chr11

86198482

-
Frame-shiftENST00000356360ENST00000393324PICALMchr11

85701292

-ME3chr11

86198482

-
Frame-shiftENST00000356360ENST00000393324PICALMchr11

85707868

-ME3chr11

86176242

-
Frame-shiftENST00000356360ENST00000393324PICALMchr11

85707868

-ME3chr11

86198482

-
Frame-shiftENST00000356360ENST00000543262PICALMchr11

85707869

-ME3chr11

86176242

-
Frame-shiftENST00000356360ENST00000543262PICALMchr11

85707869

-ME3chr11

86198482

-
Frame-shiftENST00000356360ENST00000543262PICALMchr11

85701292

-ME3chr11

86198482

-
Frame-shiftENST00000356360ENST00000543262PICALMchr11

85707868

-ME3chr11

86176242

-
Frame-shiftENST00000356360ENST00000543262PICALMchr11

85707868

-ME3chr11

86198482

-
Frame-shiftENST00000393346ENST00000323418PICALMchr11

85707869

-ME3chr11

86176242

-
Frame-shiftENST00000393346ENST00000323418PICALMchr11

85707869

-ME3chr11

86198482

-
Frame-shiftENST00000393346ENST00000323418PICALMchr11

85701292

-ME3chr11

86198482

-
Frame-shiftENST00000393346ENST00000323418PICALMchr11

85707868

-ME3chr11

86176242

-
Frame-shiftENST00000393346ENST00000323418PICALMchr11

85707868

-ME3chr11

86198482

-
Frame-shiftENST00000393346ENST00000359636PICALMchr11

85707869

-ME3chr11

86176242

-
Frame-shiftENST00000393346ENST00000359636PICALMchr11

85707869

-ME3chr11

86198482

-
Frame-shiftENST00000393346ENST00000359636PICALMchr11

85701292

-ME3chr11

86198482

-
Frame-shiftENST00000393346ENST00000359636PICALMchr11

85707868

-ME3chr11

86176242

-
Frame-shiftENST00000393346ENST00000359636PICALMchr11

85707868

-ME3chr11

86198482

-
Frame-shiftENST00000393346ENST00000393324PICALMchr11

85707869

-ME3chr11

86176242

-
Frame-shiftENST00000393346ENST00000393324PICALMchr11

85707869

-ME3chr11

86198482

-
Frame-shiftENST00000393346ENST00000393324PICALMchr11

85701292

-ME3chr11

86198482

-
Frame-shiftENST00000393346ENST00000393324PICALMchr11

85707868

-ME3chr11

86176242

-
Frame-shiftENST00000393346ENST00000393324PICALMchr11

85707868

-ME3chr11

86198482

-
Frame-shiftENST00000393346ENST00000543262PICALMchr11

85707869

-ME3chr11

86176242

-
Frame-shiftENST00000393346ENST00000543262PICALMchr11

85707869

-ME3chr11

86198482

-
Frame-shiftENST00000393346ENST00000543262PICALMchr11

85701292

-ME3chr11

86198482

-
Frame-shiftENST00000393346ENST00000543262PICALMchr11

85707868

-ME3chr11

86176242

-
Frame-shiftENST00000393346ENST00000543262PICALMchr11

85707868

-ME3chr11

86198482

-
Frame-shiftENST00000526033ENST00000323418PICALMchr11

85707869

-ME3chr11

86176242

-
Frame-shiftENST00000526033ENST00000323418PICALMchr11

85707869

-ME3chr11

86198482

-
Frame-shiftENST00000526033ENST00000323418PICALMchr11

85701292

-ME3chr11

86198482

-
Frame-shiftENST00000526033ENST00000323418PICALMchr11

85707868

-ME3chr11

86176242

-
Frame-shiftENST00000526033ENST00000323418PICALMchr11

85707868

-ME3chr11

86198482

-
Frame-shiftENST00000526033ENST00000359636PICALMchr11

85707869

-ME3chr11

86176242

-
Frame-shiftENST00000526033ENST00000359636PICALMchr11

85707869

-ME3chr11

86198482

-
Frame-shiftENST00000526033ENST00000359636PICALMchr11

85701292

-ME3chr11

86198482

-
Frame-shiftENST00000526033ENST00000359636PICALMchr11

85707868

-ME3chr11

86176242

-
Frame-shiftENST00000526033ENST00000359636PICALMchr11

85707868

-ME3chr11

86198482

-
Frame-shiftENST00000526033ENST00000393324PICALMchr11

85707869

-ME3chr11

86176242

-
Frame-shiftENST00000526033ENST00000393324PICALMchr11

85707869

-ME3chr11

86198482

-
Frame-shiftENST00000526033ENST00000393324PICALMchr11

85701292

-ME3chr11

86198482

-
Frame-shiftENST00000526033ENST00000393324PICALMchr11

85707868

-ME3chr11

86176242

-
Frame-shiftENST00000526033ENST00000393324PICALMchr11

85707868

-ME3chr11

86198482

-
Frame-shiftENST00000526033ENST00000543262PICALMchr11

85707869

-ME3chr11

86176242

-
Frame-shiftENST00000526033ENST00000543262PICALMchr11

85707869

-ME3chr11

86198482

-
Frame-shiftENST00000526033ENST00000543262PICALMchr11

85701292

-ME3chr11

86198482

-
Frame-shiftENST00000526033ENST00000543262PICALMchr11

85707868

-ME3chr11

86176242

-
Frame-shiftENST00000526033ENST00000543262PICALMchr11

85707868

-ME3chr11

86198482

-
Frame-shiftENST00000528398ENST00000323418PICALMchr11

85707869

-ME3chr11

86198482

-
Frame-shiftENST00000528398ENST00000323418PICALMchr11

85707868

-ME3chr11

86198482

-
Frame-shiftENST00000528398ENST00000359636PICALMchr11

85707869

-ME3chr11

86198482

-
Frame-shiftENST00000528398ENST00000359636PICALMchr11

85707868

-ME3chr11

86198482

-
Frame-shiftENST00000528398ENST00000393324PICALMchr11

85707869

-ME3chr11

86198482

-
Frame-shiftENST00000528398ENST00000393324PICALMchr11

85707868

-ME3chr11

86198482

-
Frame-shiftENST00000528398ENST00000543262PICALMchr11

85707869

-ME3chr11

86198482

-
Frame-shiftENST00000528398ENST00000543262PICALMchr11

85707868

-ME3chr11

86198482

-
Frame-shiftENST00000532317ENST00000323418PICALMchr11

85707869

-ME3chr11

86176242

-
Frame-shiftENST00000532317ENST00000323418PICALMchr11

85707869

-ME3chr11

86198482

-
Frame-shiftENST00000532317ENST00000323418PICALMchr11

85707868

-ME3chr11

86176242

-
Frame-shiftENST00000532317ENST00000323418PICALMchr11

85707868

-ME3chr11

86198482

-
Frame-shiftENST00000532317ENST00000359636PICALMchr11

85707869

-ME3chr11

86176242

-
Frame-shiftENST00000532317ENST00000359636PICALMchr11

85707869

-ME3chr11

86198482

-
Frame-shiftENST00000532317ENST00000359636PICALMchr11

85707868

-ME3chr11

86176242

-
Frame-shiftENST00000532317ENST00000359636PICALMchr11

85707868

-ME3chr11

86198482

-
Frame-shiftENST00000532317ENST00000393324PICALMchr11

85707869

-ME3chr11

86176242

-
Frame-shiftENST00000532317ENST00000393324PICALMchr11

85707869

-ME3chr11

86198482

-
Frame-shiftENST00000532317ENST00000393324PICALMchr11

85707868

-ME3chr11

86176242

-
Frame-shiftENST00000532317ENST00000393324PICALMchr11

85707868

-ME3chr11

86198482

-
Frame-shiftENST00000532317ENST00000543262PICALMchr11

85707869

-ME3chr11

86176242

-
Frame-shiftENST00000532317ENST00000543262PICALMchr11

85707869

-ME3chr11

86198482

-
Frame-shiftENST00000532317ENST00000543262PICALMchr11

85707868

-ME3chr11

86176242

-
Frame-shiftENST00000532317ENST00000543262PICALMchr11

85707868

-ME3chr11

86198482

-
In-frameENST00000356360ENST00000323418PICALMchr11

85779693

-ME3chr11

86270865

-
In-frameENST00000356360ENST00000359636PICALMchr11

85779693

-ME3chr11

86270865

-
In-frameENST00000356360ENST00000393324PICALMchr11

85779693

-ME3chr11

86270865

-
In-frameENST00000356360ENST00000543262PICALMchr11

85779693

-ME3chr11

86270865

-
In-frameENST00000393346ENST00000323418PICALMchr11

85779693

-ME3chr11

86270865

-
In-frameENST00000393346ENST00000359636PICALMchr11

85779693

-ME3chr11

86270865

-
In-frameENST00000393346ENST00000393324PICALMchr11

85779693

-ME3chr11

86270865

-
In-frameENST00000393346ENST00000543262PICALMchr11

85779693

-ME3chr11

86270865

-
In-frameENST00000526033ENST00000323418PICALMchr11

85779693

-ME3chr11

86270865

-
In-frameENST00000526033ENST00000359636PICALMchr11

85779693

-ME3chr11

86270865

-
In-frameENST00000526033ENST00000393324PICALMchr11

85779693

-ME3chr11

86270865

-
In-frameENST00000526033ENST00000543262PICALMchr11

85779693

-ME3chr11

86270865

-
In-frameENST00000528398ENST00000323418PICALMchr11

85707869

-ME3chr11

86176242

-
In-frameENST00000528398ENST00000323418PICALMchr11

85707868

-ME3chr11

86176242

-
In-frameENST00000528398ENST00000359636PICALMchr11

85707869

-ME3chr11

86176242

-
In-frameENST00000528398ENST00000359636PICALMchr11

85707868

-ME3chr11

86176242

-
In-frameENST00000528398ENST00000393324PICALMchr11

85707869

-ME3chr11

86176242

-
In-frameENST00000528398ENST00000393324PICALMchr11

85707868

-ME3chr11

86176242

-
In-frameENST00000528398ENST00000543262PICALMchr11

85707869

-ME3chr11

86176242

-
In-frameENST00000528398ENST00000543262PICALMchr11

85707868

-ME3chr11

86176242

-
In-frameENST00000532317ENST00000323418PICALMchr11

85779693

-ME3chr11

86270865

-
In-frameENST00000532317ENST00000359636PICALMchr11

85779693

-ME3chr11

86270865

-
In-frameENST00000532317ENST00000393324PICALMchr11

85779693

-ME3chr11

86270865

-
In-frameENST00000532317ENST00000543262PICALMchr11

85779693

-ME3chr11

86270865

-
intron-3CDSENST00000528398ENST00000323418PICALMchr11

85779693

-ME3chr11

86270865

-
intron-3CDSENST00000528398ENST00000323418PICALMchr11

85701292

-ME3chr11

86198482

-
intron-3CDSENST00000528398ENST00000359636PICALMchr11

85779693

-ME3chr11

86270865

-
intron-3CDSENST00000528398ENST00000359636PICALMchr11

85701292

-ME3chr11

86198482

-
intron-3CDSENST00000528398ENST00000393324PICALMchr11

85779693

-ME3chr11

86270865

-
intron-3CDSENST00000528398ENST00000393324PICALMchr11

85701292

-ME3chr11

86198482

-
intron-3CDSENST00000528398ENST00000543262PICALMchr11

85779693

-ME3chr11

86270865

-
intron-3CDSENST00000528398ENST00000543262PICALMchr11

85701292

-ME3chr11

86198482

-
intron-3CDSENST00000528411ENST00000323418PICALMchr11

85707869

-ME3chr11

86176242

-
intron-3CDSENST00000528411ENST00000323418PICALMchr11

85707869

-ME3chr11

86198482

-
intron-3CDSENST00000528411ENST00000323418PICALMchr11

85701292

-ME3chr11

86198482

-
intron-3CDSENST00000528411ENST00000323418PICALMchr11

85707868

-ME3chr11

86176242

-
intron-3CDSENST00000528411ENST00000323418PICALMchr11

85707868

-ME3chr11

86198482

-
intron-3CDSENST00000528411ENST00000359636PICALMchr11

85707869

-ME3chr11

86176242

-
intron-3CDSENST00000528411ENST00000359636PICALMchr11

85707869

-ME3chr11

86198482

-
intron-3CDSENST00000528411ENST00000359636PICALMchr11

85701292

-ME3chr11

86198482

-
intron-3CDSENST00000528411ENST00000359636PICALMchr11

85707868

-ME3chr11

86176242

-
intron-3CDSENST00000528411ENST00000359636PICALMchr11

85707868

-ME3chr11

86198482

-
intron-3CDSENST00000528411ENST00000393324PICALMchr11

85707869

-ME3chr11

86176242

-
intron-3CDSENST00000528411ENST00000393324PICALMchr11

85707869

-ME3chr11

86198482

-
intron-3CDSENST00000528411ENST00000393324PICALMchr11

85701292

-ME3chr11

86198482

-
intron-3CDSENST00000528411ENST00000393324PICALMchr11

85707868

-ME3chr11

86176242

-
intron-3CDSENST00000528411ENST00000393324PICALMchr11

85707868

-ME3chr11

86198482

-
intron-3CDSENST00000528411ENST00000543262PICALMchr11

85707869

-ME3chr11

86176242

-
intron-3CDSENST00000528411ENST00000543262PICALMchr11

85707869

-ME3chr11

86198482

-
intron-3CDSENST00000528411ENST00000543262PICALMchr11

85701292

-ME3chr11

86198482

-
intron-3CDSENST00000528411ENST00000543262PICALMchr11

85707868

-ME3chr11

86176242

-
intron-3CDSENST00000528411ENST00000543262PICALMchr11

85707868

-ME3chr11

86198482

-
intron-3CDSENST00000532317ENST00000323418PICALMchr11

85701292

-ME3chr11

86198482

-
intron-3CDSENST00000532317ENST00000359636PICALMchr11

85701292

-ME3chr11

86198482

-
intron-3CDSENST00000532317ENST00000393324PICALMchr11

85701292

-ME3chr11

86198482

-
intron-3CDSENST00000532317ENST00000543262PICALMchr11

85701292

-ME3chr11

86198482

-
intron-5UTRENST00000528398ENST00000525957PICALMchr11

85701292

-ME3chr11

86198482

-
intron-5UTRENST00000528411ENST00000525957PICALMchr11

85707869

-ME3chr11

86176242

-
intron-5UTRENST00000528411ENST00000525957PICALMchr11

85707869

-ME3chr11

86198482

-
intron-5UTRENST00000528411ENST00000525957PICALMchr11

85701292

-ME3chr11

86198482

-
intron-5UTRENST00000528411ENST00000525957PICALMchr11

85707868

-ME3chr11

86176242

-
intron-5UTRENST00000528411ENST00000525957PICALMchr11

85707868

-ME3chr11

86198482

-
intron-5UTRENST00000532317ENST00000525957PICALMchr11

85701292

-ME3chr11

86198482

-
intron-intronENST00000528398ENST00000525957PICALMchr11

85779693

-ME3chr11

86270865

-

check buttonORFfinder result based on the fusion transcript sequence of in-frame fusion genes.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandSeq length
(transcript)		BP loci
(transcript)		Predicted start
(transcript)		Predicted stop
(transcript)		Seq length
(amino acids)
ENST00000532317PICALMchr1185779693-ENST00000393324ME3chr1186270865-22124093102040576
ENST00000532317PICALMchr1185779693-ENST00000359636ME3chr1186270865-22124093102040576
ENST00000532317PICALMchr1185779693-ENST00000543262ME3chr1186270865-22104093102040576
ENST00000532317PICALMchr1185779693-ENST00000323418ME3chr1186270865-11894093101188293
ENST00000526033PICALMchr1185779693-ENST00000393324ME3chr1186270865-22504473482078576
ENST00000526033PICALMchr1185779693-ENST00000359636ME3chr1186270865-22504473482078576
ENST00000526033PICALMchr1185779693-ENST00000543262ME3chr1186270865-22484473482078576
ENST00000526033PICALMchr1185779693-ENST00000323418ME3chr1186270865-12274473481226292
ENST00000393346PICALMchr1185779693-ENST00000393324ME3chr1186270865-20822791801910576
ENST00000393346PICALMchr1185779693-ENST00000359636ME3chr1186270865-20822791801910576
ENST00000393346PICALMchr1185779693-ENST00000543262ME3chr1186270865-20802791801910576
ENST00000393346PICALMchr1185779693-ENST00000323418ME3chr1186270865-10592791801058292
ENST00000356360PICALMchr1185779693-ENST00000393324ME3chr1186270865-1933130311761576
ENST00000356360PICALMchr1185779693-ENST00000359636ME3chr1186270865-1933130311761576
ENST00000356360PICALMchr1185779693-ENST00000543262ME3chr1186270865-1931130311761576
ENST00000356360PICALMchr1185779693-ENST00000323418ME3chr1186270865-91013031909293
ENST00000528398PICALMchr1185707868-ENST00000393324ME3chr1186176242-246812911861301371
ENST00000528398PICALMchr1185707868-ENST00000359636ME3chr1186176242-246812911861301371
ENST00000528398PICALMchr1185707868-ENST00000543262ME3chr1186176242-246612911861301371
ENST00000528398PICALMchr1185707868-ENST00000323418ME3chr1186176242-144812911861301371
ENST00000528398PICALMchr1185707869-ENST00000393324ME3chr1186176242-246812911861301371
ENST00000528398PICALMchr1185707869-ENST00000359636ME3chr1186176242-246812911861301371
ENST00000528398PICALMchr1185707869-ENST00000543262ME3chr1186176242-246612911861301371
ENST00000528398PICALMchr1185707869-ENST00000323418ME3chr1186176242-144812911861301371

check buttonDeepORF prediction of the coding potential based on the fusion transcript sequence of in-frame fusion genes. DeepORF is a coding potential classifier based on convolutional neural network by comparing the real Ribo-seq data. If the no-coding score < 0.5 and coding score > 0.5, then the in-frame fusion transcript is predicted as being likely translated.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandNo-coding scoreCoding score
ENST00000532317ENST00000393324PICALMchr1185779693-ME3chr1186270865-0.0036897050.9963103
ENST00000532317ENST00000359636PICALMchr1185779693-ME3chr1186270865-0.0036897050.9963103
ENST00000532317ENST00000543262PICALMchr1185779693-ME3chr1186270865-0.0036543980.9963456
ENST00000532317ENST00000323418PICALMchr1185779693-ME3chr1186270865-0.0043377990.99566215
ENST00000526033ENST00000393324PICALMchr1185779693-ME3chr1186270865-0.0038905390.9961094
ENST00000526033ENST00000359636PICALMchr1185779693-ME3chr1186270865-0.0038905390.9961094
ENST00000526033ENST00000543262PICALMchr1185779693-ME3chr1186270865-0.0038521350.9961479
ENST00000526033ENST00000323418PICALMchr1185779693-ME3chr1186270865-0.0040445030.99595547
ENST00000393346ENST00000393324PICALMchr1185779693-ME3chr1186270865-0.0038220070.99617803
ENST00000393346ENST00000359636PICALMchr1185779693-ME3chr1186270865-0.0038220070.99617803
ENST00000393346ENST00000543262PICALMchr1185779693-ME3chr1186270865-0.0037868930.9962131
ENST00000393346ENST00000323418PICALMchr1185779693-ME3chr1186270865-0.00324010.99675995
ENST00000356360ENST00000393324PICALMchr1185779693-ME3chr1186270865-0.004177780.9958222
ENST00000356360ENST00000359636PICALMchr1185779693-ME3chr1186270865-0.004177780.9958222
ENST00000356360ENST00000543262PICALMchr1185779693-ME3chr1186270865-0.0041317150.9958683
ENST00000356360ENST00000323418PICALMchr1185779693-ME3chr1186270865-0.001711190.9982888
ENST00000528398ENST00000393324PICALMchr1185707868-ME3chr1186176242-0.0011001370.9988998
ENST00000528398ENST00000359636PICALMchr1185707868-ME3chr1186176242-0.0011001370.9988998
ENST00000528398ENST00000543262PICALMchr1185707868-ME3chr1186176242-0.0010940660.9989059
ENST00000528398ENST00000323418PICALMchr1185707868-ME3chr1186176242-0.000496920.999503
ENST00000528398ENST00000393324PICALMchr1185707869-ME3chr1186176242-0.0011001370.9988998
ENST00000528398ENST00000359636PICALMchr1185707869-ME3chr1186176242-0.0011001370.9988998
ENST00000528398ENST00000543262PICALMchr1185707869-ME3chr1186176242-0.0010940660.9989059
ENST00000528398ENST00000323418PICALMchr1185707869-ME3chr1186176242-0.000496920.999503

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Fusion Genomic Features for PICALM-ME3


check buttonFusionAI prediction of the potential fusion gene breakpoint based on the pre-mature RNA sequence context (+/- 5kb of individual partner genes, total 20kb length sequence). FusionAI is a fusion gene breakpoint classifier based on convolutional neural network by comparing the fusion positive and negative sequence context of ~ 20K fusion gene data. From here, we can have the relative potentency of the 20K genomic sequence how individual sequnce will be likely used as the gene fusion breakpoints.
HgeneHchrHbpHstrandTgeneTchrTbpTstrand1-pp (fusion gene breakpoint)

check buttonDistribution of 44 human genomic features loci across 20kb length fusion breakpoint regions. We integrated a total of 44 different types of human genomic feature loci information across five big categories including virus integration sites, repeats, structural variants, chromatin states, and gene expression regulation. More details are in help page.
genomic feature

check buttonDistribution of 44 human genomic features loci across 20kb length fusion breakpoint regions that are ovelapped with the top 1% feature importance score regions. More details are in help page.

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Fusion Protein Features for PICALM-ME3


check button Four levels of functional features of fusion genes
Go to FGviewer search page for the most frequent breakpoint (https://ccsmweb.uth.edu/FGviewer/chr11:85707869/chr11:86198482)
- FGviewer provides the online visualization of the retention search of the protein functional features across DNA, RNA, protein, and pathological levels.
- How to search
1. Put your fusion gene symbol.
2. Press the tab key until there will be shown the breakpoint information filled.
4. Go down and press 'Search' tab twice.
4. Go down to have the hyperlink of the search result.
5. Click the hyperlink.
6. See the FGviewer result for your fusion gene.
FGviewer

check buttonMain function of each fusion partner protein. (from UniProt)
HgeneTgene
.ME3

Q16798

FUNCTION: Transcriptional activator which is required for calcium-dependent dendritic growth and branching in cortical neurons. Recruits CREB-binding protein (CREBBP) to nuclear bodies. Component of the CREST-BRG1 complex, a multiprotein complex that regulates promoter activation by orchestrating a calcium-dependent release of a repressor complex and a recruitment of an activator complex. In resting neurons, transcription of the c-FOS promoter is inhibited by BRG1-dependent recruitment of a phospho-RB1-HDAC1 repressor complex. Upon calcium influx, RB1 is dephosphorylated by calcineurin, which leads to release of the repressor complex. At the same time, there is increased recruitment of CREBBP to the promoter by a CREST-dependent mechanism, which leads to transcriptional activation. The CREST-BRG1 complex also binds to the NR2B promoter, and activity-dependent induction of NR2B expression involves a release of HDAC1 and recruitment of CREBBP (By similarity). {ECO:0000250}.

check buttonRetention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at

download page


* Minus value of BPloci means that the break pointn is located before the CDS.
- In-frame and retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
HgenePICALMchr11:85707868chr11:86176242ENST00000356360-121914_145419633.0DomainENTH
HgenePICALMchr11:85707868chr11:86176242ENST00000393346-122014_145419653.0DomainENTH
HgenePICALMchr11:85707868chr11:86176242ENST00000526033-122014_145419646.0DomainENTH
HgenePICALMchr11:85707868chr11:86176242ENST00000528398-121914_145368552.0DomainENTH
HgenePICALMchr11:85707868chr11:86176242ENST00000532317-122014_145419611.0DomainENTH
HgenePICALMchr11:85707869chr11:86176242ENST00000356360-121914_145419633.0DomainENTH
HgenePICALMchr11:85707869chr11:86176242ENST00000393346-122014_145419653.0DomainENTH
HgenePICALMchr11:85707869chr11:86176242ENST00000526033-122014_145419646.0DomainENTH
HgenePICALMchr11:85707869chr11:86176242ENST00000528398-121914_145368552.0DomainENTH
HgenePICALMchr11:85707869chr11:86176242ENST00000532317-122014_145419611.0DomainENTH

- In-frame and not-retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
HgenePICALMchr11:85779693chr11:86270865ENST00000356360-11914_14543633.0DomainENTH
HgenePICALMchr11:85779693chr11:86270865ENST00000393346-12014_14543653.0DomainENTH
HgenePICALMchr11:85779693chr11:86270865ENST00000526033-12014_14543646.0DomainENTH
HgenePICALMchr11:85779693chr11:86270865ENST00000528398-11914_1450552.0DomainENTH
HgenePICALMchr11:85779693chr11:86270865ENST00000532317-12014_14543611.0DomainENTH


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Fusion Gene Sequence for PICALM-ME3


check button For in-frame fusion transcripts, we provide the fusion transcript sequences and fusion amino acid sequences. To have fusion amino acid sequence, we ran ORFfinder and chose the longest ORF among the all predicted ones.
>65153_65153_1_PICALM-ME3_PICALM_chr11_85707868_ENST00000528398_ME3_chr11_86176242_ENST00000323418_length(transcript)=1448nt_BP=1291nt
TATGTGTTTCCTGTCCTATTCCACACCCTAGAGAATGAATACCGGCCAGCTAGTATCTAAATTTAGAATGGCAGCAACGTGTCGGGTTTT
CGGAGTAGAGATAAACAAAACCAGGTGACATTTCCAAGCCTCTCAAGGAAAGGGGGGAAAAAACCTTTCTGGGACTTAATTCAGTGCACA
AATGAGATGAATGTGAACATCCCACAGTTGGCAGACAGTTTATTTGAAAGAACTACTAATAGTAGTTGGGTGGTGGTCTTCAAATCTCTC
ATTACAACTCATCATTTGATGGTGTATGGAAATGAGCGTTTTATTCAGTATTTGGCTTCAAGAAACACGTTGTTTAACTTAAGCAATTTT
TTGGATAAAAGTGGATTGCAAGGATATGACATGTCTACATTTATTAGGCGGTATAGTAGATATTTAAATGAGAAAGCAGTTTCATACAGA
CAAGTTGCATTTGATTTCACAAAAGTGAAGAGAGGGGCTGATGGAGTTATGAGAACAATGAACACAGAAAAACTCCTAAAAACTGTACCA
ATTATTCAGAATCAGATGGATGCACTTCTTGATTTTAATGTTAATAGCAATGAACTTACAAATGGGGTAATAAATGCTGCCTTCATGCTC
CTGTTCAAAGATGCCATTAGACTGTTTGCAGCATACAATGAAGGAATTATTAATTTGTTGGAAAAATATTTTGATATGAAAAAGAACCAA
TGCAAAGAAGGTCTTGACATCTATAAGAAGTTCCTAACTAGGATGACAAGAATCTCAGAGTTCCTCAAAGTTGCAGAGCAAGTTGGAATT
GACAGAGGTGATATACCAGACCTTTCACAGGCCCCTAGCAGTCTTCTTGATGCTTTGGAACAACATTTAGCTTCCTTGGAAGGAAAGAAA
ATCAAAGATTCTACAGCTGCAAGCAGGGCAACTACACTTTCCAATGCAGTGTCTTCCCTGGCAAGCACTGGTCTATCTCTGACCAAAGTG
GATGAAAGGGAAAAGCAGGCAGCATTAGAGGAAGAACAGGCACGTTTGAAAGCTTTAAAGGAACAGCGCCTAAAAGAACTTGCAAAGAAA
CCTCATACCTCTTTAACAACTGCAGCCTCTCCTGTATCCACCTCAGCAGGAGGGATAATGACTGCACCAGCCATTGACATATTTTCTACC
CCTAGTTCTTCTAACAGCACATCAAAGCTGCCCAATGATCTGCTTGATTTGCAGCAGCCAACTTTTCACCCATCTGTACATCCTATGTCA
ACTGCTTCTCAGGTAGCAAGTACATGGGGAGGTTTGGAATAAATTGCCTCATCCAATTTGAAGACTTCGCCAATGCCAATGCCTTCCGCC
TGCTCAACAAATACCGTAACAAGTACTGCATGTTCAATGATGACATCCAAGATGACTTCTCCAGAGGCCCAAAGAGGTCACAACTTTTCT

>65153_65153_1_PICALM-ME3_PICALM_chr11_85707868_ENST00000528398_ME3_chr11_86176242_ENST00000323418_length(amino acids)=371AA_BP=
MNVNIPQLADSLFERTTNSSWVVVFKSLITTHHLMVYGNERFIQYLASRNTLFNLSNFLDKSGLQGYDMSTFIRRYSRYLNEKAVSYRQV
AFDFTKVKRGADGVMRTMNTEKLLKTVPIIQNQMDALLDFNVNSNELTNGVINAAFMLLFKDAIRLFAAYNEGIINLLEKYFDMKKNQCK
EGLDIYKKFLTRMTRISEFLKVAEQVGIDRGDIPDLSQAPSSLLDALEQHLASLEGKKIKDSTAASRATTLSNAVSSLASTGLSLTKVDE
REKQAALEEEQARLKALKEQRLKELAKKPHTSLTTAASPVSTSAGGIMTAPAIDIFSTPSSSNSTSKLPNDLLDLQQPTFHPSVHPMSTA

--------------------------------------------------------------
>65153_65153_2_PICALM-ME3_PICALM_chr11_85707868_ENST00000528398_ME3_chr11_86176242_ENST00000359636_length(transcript)=2468nt_BP=1291nt
TATGTGTTTCCTGTCCTATTCCACACCCTAGAGAATGAATACCGGCCAGCTAGTATCTAAATTTAGAATGGCAGCAACGTGTCGGGTTTT
CGGAGTAGAGATAAACAAAACCAGGTGACATTTCCAAGCCTCTCAAGGAAAGGGGGGAAAAAACCTTTCTGGGACTTAATTCAGTGCACA
AATGAGATGAATGTGAACATCCCACAGTTGGCAGACAGTTTATTTGAAAGAACTACTAATAGTAGTTGGGTGGTGGTCTTCAAATCTCTC
ATTACAACTCATCATTTGATGGTGTATGGAAATGAGCGTTTTATTCAGTATTTGGCTTCAAGAAACACGTTGTTTAACTTAAGCAATTTT
TTGGATAAAAGTGGATTGCAAGGATATGACATGTCTACATTTATTAGGCGGTATAGTAGATATTTAAATGAGAAAGCAGTTTCATACAGA
CAAGTTGCATTTGATTTCACAAAAGTGAAGAGAGGGGCTGATGGAGTTATGAGAACAATGAACACAGAAAAACTCCTAAAAACTGTACCA
ATTATTCAGAATCAGATGGATGCACTTCTTGATTTTAATGTTAATAGCAATGAACTTACAAATGGGGTAATAAATGCTGCCTTCATGCTC
CTGTTCAAAGATGCCATTAGACTGTTTGCAGCATACAATGAAGGAATTATTAATTTGTTGGAAAAATATTTTGATATGAAAAAGAACCAA
TGCAAAGAAGGTCTTGACATCTATAAGAAGTTCCTAACTAGGATGACAAGAATCTCAGAGTTCCTCAAAGTTGCAGAGCAAGTTGGAATT
GACAGAGGTGATATACCAGACCTTTCACAGGCCCCTAGCAGTCTTCTTGATGCTTTGGAACAACATTTAGCTTCCTTGGAAGGAAAGAAA
ATCAAAGATTCTACAGCTGCAAGCAGGGCAACTACACTTTCCAATGCAGTGTCTTCCCTGGCAAGCACTGGTCTATCTCTGACCAAAGTG
GATGAAAGGGAAAAGCAGGCAGCATTAGAGGAAGAACAGGCACGTTTGAAAGCTTTAAAGGAACAGCGCCTAAAAGAACTTGCAAAGAAA
CCTCATACCTCTTTAACAACTGCAGCCTCTCCTGTATCCACCTCAGCAGGAGGGATAATGACTGCACCAGCCATTGACATATTTTCTACC
CCTAGTTCTTCTAACAGCACATCAAAGCTGCCCAATGATCTGCTTGATTTGCAGCAGCCAACTTTTCACCCATCTGTACATCCTATGTCA
ACTGCTTCTCAGGTAGCAAGTACATGGGGAGGTTTGGAATAAATTGCCTCATCCAATTTGAAGACTTCGCCAATGCCAATGCCTTCCGCC
TGCTCAACAAATACCGTAACAAGTACTGCATGTTCAATGATGACATCCAAGGCACAGCCTCCGTTGCTGTGGCAGGGATCTTGGCTGCTC
TGCGAATCACCAAGAACAAGCTTTCCAATCACGTGTTTGTTTTCCAAGGTGCAGGCGAGGCAGCTATGGGCATTGCCCACCTCCTTGTCA
TGGCCCTAGAGAAAGAAGGTGTACCGAAGGCAGAGGCCACAAGAAAGATCTGGATGGTGGACTCTAAAGGGCTCATTGTCAAGGGGAGGA
GCCACCTGAACCATGAAAAGGAGATGTTTGCCCAAGACCATCCTGAAGTCAACTCCCTGGAGGAGGTGGTGAGGCTGGTGAAGCCCACAG
CCATCATAGGTGTTGCTGCCATCGCAGGAGCCTTCACGGAGCAGATTCTGAGGGACATGGCCTCCTTCCACGAGCGCCCTATCATCTTTG
CCCTGAGCAACCCCACCAGCAAGGCCGAGTGCACGGCTGAGAAGTGCTACCGGGTCACCGAGGGCCGAGGGATTTTTGCCAGTGGAAGTC
CTTTTAAGAGTGTGACTCTGGAAGATGGCAAGACCTTCATTCCTGGGCAGGGAAACAATGCTTACGTGTTCCCCGGGGTGGCACTGGGAG
TCATCGCCGGCGGGATCCGGCACATCCCAGATGAGATCTTCCTCCTGACAGCAGAGCAAATTGCCCAGGAAGTCTCTGAGCAGCATCTGT
CCCAGGGGAGACTCTACCCACCACTCAGCACCATCCGAGACGTGTCTTTGAGAATTGCCATCAAAGTTCTCGACTACGCGTACAAACACA
ACCTGGCTTCCTACTACCCAGAGCCTAAGGACAAGGAGGCTTTTGTAAGATCCCTGGTCTACACTCCAGACTATGACTCCTTTACACTGG
ACAGCTACACTTGGCCCAAGGAAGCCATGAATGTTCAGACGGTCTGAGGCAGTCTCAGAGGCTAGTATGGGGCTAGATGAAGCCCAGAGT
AACACCCACAATATAAATGGGTTCCAAAATGGCCCAAGTGAATCCTTGTCGCTGTGTTTTTTCTTTTAAACTTTCTGGTGTGAGAGGAGA

>65153_65153_2_PICALM-ME3_PICALM_chr11_85707868_ENST00000528398_ME3_chr11_86176242_ENST00000359636_length(amino acids)=371AA_BP=
MNVNIPQLADSLFERTTNSSWVVVFKSLITTHHLMVYGNERFIQYLASRNTLFNLSNFLDKSGLQGYDMSTFIRRYSRYLNEKAVSYRQV
AFDFTKVKRGADGVMRTMNTEKLLKTVPIIQNQMDALLDFNVNSNELTNGVINAAFMLLFKDAIRLFAAYNEGIINLLEKYFDMKKNQCK
EGLDIYKKFLTRMTRISEFLKVAEQVGIDRGDIPDLSQAPSSLLDALEQHLASLEGKKIKDSTAASRATTLSNAVSSLASTGLSLTKVDE
REKQAALEEEQARLKALKEQRLKELAKKPHTSLTTAASPVSTSAGGIMTAPAIDIFSTPSSSNSTSKLPNDLLDLQQPTFHPSVHPMSTA

--------------------------------------------------------------
>65153_65153_3_PICALM-ME3_PICALM_chr11_85707868_ENST00000528398_ME3_chr11_86176242_ENST00000393324_length(transcript)=2468nt_BP=1291nt
TATGTGTTTCCTGTCCTATTCCACACCCTAGAGAATGAATACCGGCCAGCTAGTATCTAAATTTAGAATGGCAGCAACGTGTCGGGTTTT
CGGAGTAGAGATAAACAAAACCAGGTGACATTTCCAAGCCTCTCAAGGAAAGGGGGGAAAAAACCTTTCTGGGACTTAATTCAGTGCACA
AATGAGATGAATGTGAACATCCCACAGTTGGCAGACAGTTTATTTGAAAGAACTACTAATAGTAGTTGGGTGGTGGTCTTCAAATCTCTC
ATTACAACTCATCATTTGATGGTGTATGGAAATGAGCGTTTTATTCAGTATTTGGCTTCAAGAAACACGTTGTTTAACTTAAGCAATTTT
TTGGATAAAAGTGGATTGCAAGGATATGACATGTCTACATTTATTAGGCGGTATAGTAGATATTTAAATGAGAAAGCAGTTTCATACAGA
CAAGTTGCATTTGATTTCACAAAAGTGAAGAGAGGGGCTGATGGAGTTATGAGAACAATGAACACAGAAAAACTCCTAAAAACTGTACCA
ATTATTCAGAATCAGATGGATGCACTTCTTGATTTTAATGTTAATAGCAATGAACTTACAAATGGGGTAATAAATGCTGCCTTCATGCTC
CTGTTCAAAGATGCCATTAGACTGTTTGCAGCATACAATGAAGGAATTATTAATTTGTTGGAAAAATATTTTGATATGAAAAAGAACCAA
TGCAAAGAAGGTCTTGACATCTATAAGAAGTTCCTAACTAGGATGACAAGAATCTCAGAGTTCCTCAAAGTTGCAGAGCAAGTTGGAATT
GACAGAGGTGATATACCAGACCTTTCACAGGCCCCTAGCAGTCTTCTTGATGCTTTGGAACAACATTTAGCTTCCTTGGAAGGAAAGAAA
ATCAAAGATTCTACAGCTGCAAGCAGGGCAACTACACTTTCCAATGCAGTGTCTTCCCTGGCAAGCACTGGTCTATCTCTGACCAAAGTG
GATGAAAGGGAAAAGCAGGCAGCATTAGAGGAAGAACAGGCACGTTTGAAAGCTTTAAAGGAACAGCGCCTAAAAGAACTTGCAAAGAAA
CCTCATACCTCTTTAACAACTGCAGCCTCTCCTGTATCCACCTCAGCAGGAGGGATAATGACTGCACCAGCCATTGACATATTTTCTACC
CCTAGTTCTTCTAACAGCACATCAAAGCTGCCCAATGATCTGCTTGATTTGCAGCAGCCAACTTTTCACCCATCTGTACATCCTATGTCA
ACTGCTTCTCAGGTAGCAAGTACATGGGGAGGTTTGGAATAAATTGCCTCATCCAATTTGAAGACTTCGCCAATGCCAATGCCTTCCGCC
TGCTCAACAAATACCGTAACAAGTACTGCATGTTCAATGATGACATCCAAGGCACAGCCTCCGTTGCTGTGGCAGGGATCTTGGCTGCTC
TGCGAATCACCAAGAACAAGCTTTCCAATCACGTGTTTGTTTTCCAAGGTGCAGGCGAGGCAGCTATGGGCATTGCCCACCTCCTTGTCA
TGGCCCTAGAGAAAGAAGGTGTACCGAAGGCAGAGGCCACAAGAAAGATCTGGATGGTGGACTCTAAAGGGCTCATTGTCAAGGGGAGGA
GCCACCTGAACCATGAAAAGGAGATGTTTGCCCAAGACCATCCTGAAGTCAACTCCCTGGAGGAGGTGGTGAGGCTGGTGAAGCCCACAG
CCATCATAGGTGTTGCTGCCATCGCAGGAGCCTTCACGGAGCAGATTCTGAGGGACATGGCCTCCTTCCACGAGCGCCCTATCATCTTTG
CCCTGAGCAACCCCACCAGCAAGGCCGAGTGCACGGCTGAGAAGTGCTACCGGGTCACCGAGGGCCGAGGGATTTTTGCCAGTGGAAGTC
CTTTTAAGAGTGTGACTCTGGAAGATGGCAAGACCTTCATTCCTGGGCAGGGAAACAATGCTTACGTGTTCCCCGGGGTGGCACTGGGAG
TCATCGCCGGCGGGATCCGGCACATCCCAGATGAGATCTTCCTCCTGACAGCAGAGCAAATTGCCCAGGAAGTCTCTGAGCAGCATCTGT
CCCAGGGGAGACTCTACCCACCACTCAGCACCATCCGAGACGTGTCTTTGAGAATTGCCATCAAAGTTCTCGACTACGCGTACAAACACA
ACCTGGCTTCCTACTACCCAGAGCCTAAGGACAAGGAGGCTTTTGTAAGATCCCTGGTCTACACTCCAGACTATGACTCCTTTACACTGG
ACAGCTACACTTGGCCCAAGGAAGCCATGAATGTTCAGACGGTCTGAGGCAGTCTCAGAGGCTAGTATGGGGCTAGATGAAGCCCAGAGT
AACACCCACAATATAAATGGGTTCCAAAATGGCCCAAGTGAATCCTTGTCGCTGTGTTTTTTCTTTTAAACTTTCTGGTGTGAGAGGAGA

>65153_65153_3_PICALM-ME3_PICALM_chr11_85707868_ENST00000528398_ME3_chr11_86176242_ENST00000393324_length(amino acids)=371AA_BP=
MNVNIPQLADSLFERTTNSSWVVVFKSLITTHHLMVYGNERFIQYLASRNTLFNLSNFLDKSGLQGYDMSTFIRRYSRYLNEKAVSYRQV
AFDFTKVKRGADGVMRTMNTEKLLKTVPIIQNQMDALLDFNVNSNELTNGVINAAFMLLFKDAIRLFAAYNEGIINLLEKYFDMKKNQCK
EGLDIYKKFLTRMTRISEFLKVAEQVGIDRGDIPDLSQAPSSLLDALEQHLASLEGKKIKDSTAASRATTLSNAVSSLASTGLSLTKVDE
REKQAALEEEQARLKALKEQRLKELAKKPHTSLTTAASPVSTSAGGIMTAPAIDIFSTPSSSNSTSKLPNDLLDLQQPTFHPSVHPMSTA

--------------------------------------------------------------
>65153_65153_4_PICALM-ME3_PICALM_chr11_85707868_ENST00000528398_ME3_chr11_86176242_ENST00000543262_length(transcript)=2466nt_BP=1291nt
TATGTGTTTCCTGTCCTATTCCACACCCTAGAGAATGAATACCGGCCAGCTAGTATCTAAATTTAGAATGGCAGCAACGTGTCGGGTTTT
CGGAGTAGAGATAAACAAAACCAGGTGACATTTCCAAGCCTCTCAAGGAAAGGGGGGAAAAAACCTTTCTGGGACTTAATTCAGTGCACA
AATGAGATGAATGTGAACATCCCACAGTTGGCAGACAGTTTATTTGAAAGAACTACTAATAGTAGTTGGGTGGTGGTCTTCAAATCTCTC
ATTACAACTCATCATTTGATGGTGTATGGAAATGAGCGTTTTATTCAGTATTTGGCTTCAAGAAACACGTTGTTTAACTTAAGCAATTTT
TTGGATAAAAGTGGATTGCAAGGATATGACATGTCTACATTTATTAGGCGGTATAGTAGATATTTAAATGAGAAAGCAGTTTCATACAGA
CAAGTTGCATTTGATTTCACAAAAGTGAAGAGAGGGGCTGATGGAGTTATGAGAACAATGAACACAGAAAAACTCCTAAAAACTGTACCA
ATTATTCAGAATCAGATGGATGCACTTCTTGATTTTAATGTTAATAGCAATGAACTTACAAATGGGGTAATAAATGCTGCCTTCATGCTC
CTGTTCAAAGATGCCATTAGACTGTTTGCAGCATACAATGAAGGAATTATTAATTTGTTGGAAAAATATTTTGATATGAAAAAGAACCAA
TGCAAAGAAGGTCTTGACATCTATAAGAAGTTCCTAACTAGGATGACAAGAATCTCAGAGTTCCTCAAAGTTGCAGAGCAAGTTGGAATT
GACAGAGGTGATATACCAGACCTTTCACAGGCCCCTAGCAGTCTTCTTGATGCTTTGGAACAACATTTAGCTTCCTTGGAAGGAAAGAAA
ATCAAAGATTCTACAGCTGCAAGCAGGGCAACTACACTTTCCAATGCAGTGTCTTCCCTGGCAAGCACTGGTCTATCTCTGACCAAAGTG
GATGAAAGGGAAAAGCAGGCAGCATTAGAGGAAGAACAGGCACGTTTGAAAGCTTTAAAGGAACAGCGCCTAAAAGAACTTGCAAAGAAA
CCTCATACCTCTTTAACAACTGCAGCCTCTCCTGTATCCACCTCAGCAGGAGGGATAATGACTGCACCAGCCATTGACATATTTTCTACC
CCTAGTTCTTCTAACAGCACATCAAAGCTGCCCAATGATCTGCTTGATTTGCAGCAGCCAACTTTTCACCCATCTGTACATCCTATGTCA
ACTGCTTCTCAGGTAGCAAGTACATGGGGAGGTTTGGAATAAATTGCCTCATCCAATTTGAAGACTTCGCCAATGCCAATGCCTTCCGCC
TGCTCAACAAATACCGTAACAAGTACTGCATGTTCAATGATGACATCCAAGGCACAGCCTCCGTTGCTGTGGCAGGGATCTTGGCTGCTC
TGCGAATCACCAAGAACAAGCTTTCCAATCACGTGTTTGTTTTCCAAGGTGCAGGCGAGGCAGCTATGGGCATTGCCCACCTCCTTGTCA
TGGCCCTAGAGAAAGAAGGTGTACCGAAGGCAGAGGCCACAAGAAAGATCTGGATGGTGGACTCTAAAGGGCTCATTGTCAAGGGGAGGA
GCCACCTGAACCATGAAAAGGAGATGTTTGCCCAAGACCATCCTGAAGTCAACTCCCTGGAGGAGGTGGTGAGGCTGGTGAAGCCCACAG
CCATCATAGGTGTTGCTGCCATCGCAGGAGCCTTCACGGAGCAGATTCTGAGGGACATGGCCTCCTTCCACGAGCGCCCTATCATCTTTG
CCCTGAGCAACCCCACCAGCAAGGCCGAGTGCACGGCTGAGAAGTGCTACCGGGTCACCGAGGGCCGAGGGATTTTTGCCAGTGGAAGTC
CTTTTAAGAGTGTGACTCTGGAAGATGGCAAGACCTTCATTCCTGGGCAGGGAAACAATGCTTACGTGTTCCCCGGGGTGGCACTGGGAG
TCATCGCCGGCGGGATCCGGCACATCCCAGATGAGATCTTCCTCCTGACAGCAGAGCAAATTGCCCAGGAAGTCTCTGAGCAGCATCTGT
CCCAGGGGAGACTCTACCCACCACTCAGCACCATCCGAGACGTGTCTTTGAGAATTGCCATCAAAGTTCTCGACTACGCGTACAAACACA
ACCTGGCTTCCTACTACCCAGAGCCTAAGGACAAGGAGGCTTTTGTAAGATCCCTGGTCTACACTCCAGACTATGACTCCTTTACACTGG
ACAGCTACACTTGGCCCAAGGAAGCCATGAATGTTCAGACGGTCTGAGGCAGTCTCAGAGGCTAGTATGGGGCTAGATGAAGCCCAGAGT
AACACCCACAATATAAATGGGTTCCAAAATGGCCCAAGTGAATCCTTGTCGCTGTGTTTTTTCTTTTAAACTTTCTGGTGTGAGAGGAGA

>65153_65153_4_PICALM-ME3_PICALM_chr11_85707868_ENST00000528398_ME3_chr11_86176242_ENST00000543262_length(amino acids)=371AA_BP=
MNVNIPQLADSLFERTTNSSWVVVFKSLITTHHLMVYGNERFIQYLASRNTLFNLSNFLDKSGLQGYDMSTFIRRYSRYLNEKAVSYRQV
AFDFTKVKRGADGVMRTMNTEKLLKTVPIIQNQMDALLDFNVNSNELTNGVINAAFMLLFKDAIRLFAAYNEGIINLLEKYFDMKKNQCK
EGLDIYKKFLTRMTRISEFLKVAEQVGIDRGDIPDLSQAPSSLLDALEQHLASLEGKKIKDSTAASRATTLSNAVSSLASTGLSLTKVDE
REKQAALEEEQARLKALKEQRLKELAKKPHTSLTTAASPVSTSAGGIMTAPAIDIFSTPSSSNSTSKLPNDLLDLQQPTFHPSVHPMSTA

--------------------------------------------------------------
>65153_65153_5_PICALM-ME3_PICALM_chr11_85707869_ENST00000528398_ME3_chr11_86176242_ENST00000323418_length(transcript)=1448nt_BP=1291nt
TATGTGTTTCCTGTCCTATTCCACACCCTAGAGAATGAATACCGGCCAGCTAGTATCTAAATTTAGAATGGCAGCAACGTGTCGGGTTTT
CGGAGTAGAGATAAACAAAACCAGGTGACATTTCCAAGCCTCTCAAGGAAAGGGGGGAAAAAACCTTTCTGGGACTTAATTCAGTGCACA
AATGAGATGAATGTGAACATCCCACAGTTGGCAGACAGTTTATTTGAAAGAACTACTAATAGTAGTTGGGTGGTGGTCTTCAAATCTCTC
ATTACAACTCATCATTTGATGGTGTATGGAAATGAGCGTTTTATTCAGTATTTGGCTTCAAGAAACACGTTGTTTAACTTAAGCAATTTT
TTGGATAAAAGTGGATTGCAAGGATATGACATGTCTACATTTATTAGGCGGTATAGTAGATATTTAAATGAGAAAGCAGTTTCATACAGA
CAAGTTGCATTTGATTTCACAAAAGTGAAGAGAGGGGCTGATGGAGTTATGAGAACAATGAACACAGAAAAACTCCTAAAAACTGTACCA
ATTATTCAGAATCAGATGGATGCACTTCTTGATTTTAATGTTAATAGCAATGAACTTACAAATGGGGTAATAAATGCTGCCTTCATGCTC
CTGTTCAAAGATGCCATTAGACTGTTTGCAGCATACAATGAAGGAATTATTAATTTGTTGGAAAAATATTTTGATATGAAAAAGAACCAA
TGCAAAGAAGGTCTTGACATCTATAAGAAGTTCCTAACTAGGATGACAAGAATCTCAGAGTTCCTCAAAGTTGCAGAGCAAGTTGGAATT
GACAGAGGTGATATACCAGACCTTTCACAGGCCCCTAGCAGTCTTCTTGATGCTTTGGAACAACATTTAGCTTCCTTGGAAGGAAAGAAA
ATCAAAGATTCTACAGCTGCAAGCAGGGCAACTACACTTTCCAATGCAGTGTCTTCCCTGGCAAGCACTGGTCTATCTCTGACCAAAGTG
GATGAAAGGGAAAAGCAGGCAGCATTAGAGGAAGAACAGGCACGTTTGAAAGCTTTAAAGGAACAGCGCCTAAAAGAACTTGCAAAGAAA
CCTCATACCTCTTTAACAACTGCAGCCTCTCCTGTATCCACCTCAGCAGGAGGGATAATGACTGCACCAGCCATTGACATATTTTCTACC
CCTAGTTCTTCTAACAGCACATCAAAGCTGCCCAATGATCTGCTTGATTTGCAGCAGCCAACTTTTCACCCATCTGTACATCCTATGTCA
ACTGCTTCTCAGGTAGCAAGTACATGGGGAGGTTTGGAATAAATTGCCTCATCCAATTTGAAGACTTCGCCAATGCCAATGCCTTCCGCC
TGCTCAACAAATACCGTAACAAGTACTGCATGTTCAATGATGACATCCAAGATGACTTCTCCAGAGGCCCAAAGAGGTCACAACTTTTCT

>65153_65153_5_PICALM-ME3_PICALM_chr11_85707869_ENST00000528398_ME3_chr11_86176242_ENST00000323418_length(amino acids)=371AA_BP=
MNVNIPQLADSLFERTTNSSWVVVFKSLITTHHLMVYGNERFIQYLASRNTLFNLSNFLDKSGLQGYDMSTFIRRYSRYLNEKAVSYRQV
AFDFTKVKRGADGVMRTMNTEKLLKTVPIIQNQMDALLDFNVNSNELTNGVINAAFMLLFKDAIRLFAAYNEGIINLLEKYFDMKKNQCK
EGLDIYKKFLTRMTRISEFLKVAEQVGIDRGDIPDLSQAPSSLLDALEQHLASLEGKKIKDSTAASRATTLSNAVSSLASTGLSLTKVDE
REKQAALEEEQARLKALKEQRLKELAKKPHTSLTTAASPVSTSAGGIMTAPAIDIFSTPSSSNSTSKLPNDLLDLQQPTFHPSVHPMSTA

--------------------------------------------------------------
>65153_65153_6_PICALM-ME3_PICALM_chr11_85707869_ENST00000528398_ME3_chr11_86176242_ENST00000359636_length(transcript)=2468nt_BP=1291nt
TATGTGTTTCCTGTCCTATTCCACACCCTAGAGAATGAATACCGGCCAGCTAGTATCTAAATTTAGAATGGCAGCAACGTGTCGGGTTTT
CGGAGTAGAGATAAACAAAACCAGGTGACATTTCCAAGCCTCTCAAGGAAAGGGGGGAAAAAACCTTTCTGGGACTTAATTCAGTGCACA
AATGAGATGAATGTGAACATCCCACAGTTGGCAGACAGTTTATTTGAAAGAACTACTAATAGTAGTTGGGTGGTGGTCTTCAAATCTCTC
ATTACAACTCATCATTTGATGGTGTATGGAAATGAGCGTTTTATTCAGTATTTGGCTTCAAGAAACACGTTGTTTAACTTAAGCAATTTT
TTGGATAAAAGTGGATTGCAAGGATATGACATGTCTACATTTATTAGGCGGTATAGTAGATATTTAAATGAGAAAGCAGTTTCATACAGA
CAAGTTGCATTTGATTTCACAAAAGTGAAGAGAGGGGCTGATGGAGTTATGAGAACAATGAACACAGAAAAACTCCTAAAAACTGTACCA
ATTATTCAGAATCAGATGGATGCACTTCTTGATTTTAATGTTAATAGCAATGAACTTACAAATGGGGTAATAAATGCTGCCTTCATGCTC
CTGTTCAAAGATGCCATTAGACTGTTTGCAGCATACAATGAAGGAATTATTAATTTGTTGGAAAAATATTTTGATATGAAAAAGAACCAA
TGCAAAGAAGGTCTTGACATCTATAAGAAGTTCCTAACTAGGATGACAAGAATCTCAGAGTTCCTCAAAGTTGCAGAGCAAGTTGGAATT
GACAGAGGTGATATACCAGACCTTTCACAGGCCCCTAGCAGTCTTCTTGATGCTTTGGAACAACATTTAGCTTCCTTGGAAGGAAAGAAA
ATCAAAGATTCTACAGCTGCAAGCAGGGCAACTACACTTTCCAATGCAGTGTCTTCCCTGGCAAGCACTGGTCTATCTCTGACCAAAGTG
GATGAAAGGGAAAAGCAGGCAGCATTAGAGGAAGAACAGGCACGTTTGAAAGCTTTAAAGGAACAGCGCCTAAAAGAACTTGCAAAGAAA
CCTCATACCTCTTTAACAACTGCAGCCTCTCCTGTATCCACCTCAGCAGGAGGGATAATGACTGCACCAGCCATTGACATATTTTCTACC
CCTAGTTCTTCTAACAGCACATCAAAGCTGCCCAATGATCTGCTTGATTTGCAGCAGCCAACTTTTCACCCATCTGTACATCCTATGTCA
ACTGCTTCTCAGGTAGCAAGTACATGGGGAGGTTTGGAATAAATTGCCTCATCCAATTTGAAGACTTCGCCAATGCCAATGCCTTCCGCC
TGCTCAACAAATACCGTAACAAGTACTGCATGTTCAATGATGACATCCAAGGCACAGCCTCCGTTGCTGTGGCAGGGATCTTGGCTGCTC
TGCGAATCACCAAGAACAAGCTTTCCAATCACGTGTTTGTTTTCCAAGGTGCAGGCGAGGCAGCTATGGGCATTGCCCACCTCCTTGTCA
TGGCCCTAGAGAAAGAAGGTGTACCGAAGGCAGAGGCCACAAGAAAGATCTGGATGGTGGACTCTAAAGGGCTCATTGTCAAGGGGAGGA
GCCACCTGAACCATGAAAAGGAGATGTTTGCCCAAGACCATCCTGAAGTCAACTCCCTGGAGGAGGTGGTGAGGCTGGTGAAGCCCACAG
CCATCATAGGTGTTGCTGCCATCGCAGGAGCCTTCACGGAGCAGATTCTGAGGGACATGGCCTCCTTCCACGAGCGCCCTATCATCTTTG
CCCTGAGCAACCCCACCAGCAAGGCCGAGTGCACGGCTGAGAAGTGCTACCGGGTCACCGAGGGCCGAGGGATTTTTGCCAGTGGAAGTC
CTTTTAAGAGTGTGACTCTGGAAGATGGCAAGACCTTCATTCCTGGGCAGGGAAACAATGCTTACGTGTTCCCCGGGGTGGCACTGGGAG
TCATCGCCGGCGGGATCCGGCACATCCCAGATGAGATCTTCCTCCTGACAGCAGAGCAAATTGCCCAGGAAGTCTCTGAGCAGCATCTGT
CCCAGGGGAGACTCTACCCACCACTCAGCACCATCCGAGACGTGTCTTTGAGAATTGCCATCAAAGTTCTCGACTACGCGTACAAACACA
ACCTGGCTTCCTACTACCCAGAGCCTAAGGACAAGGAGGCTTTTGTAAGATCCCTGGTCTACACTCCAGACTATGACTCCTTTACACTGG
ACAGCTACACTTGGCCCAAGGAAGCCATGAATGTTCAGACGGTCTGAGGCAGTCTCAGAGGCTAGTATGGGGCTAGATGAAGCCCAGAGT
AACACCCACAATATAAATGGGTTCCAAAATGGCCCAAGTGAATCCTTGTCGCTGTGTTTTTTCTTTTAAACTTTCTGGTGTGAGAGGAGA

>65153_65153_6_PICALM-ME3_PICALM_chr11_85707869_ENST00000528398_ME3_chr11_86176242_ENST00000359636_length(amino acids)=371AA_BP=
MNVNIPQLADSLFERTTNSSWVVVFKSLITTHHLMVYGNERFIQYLASRNTLFNLSNFLDKSGLQGYDMSTFIRRYSRYLNEKAVSYRQV
AFDFTKVKRGADGVMRTMNTEKLLKTVPIIQNQMDALLDFNVNSNELTNGVINAAFMLLFKDAIRLFAAYNEGIINLLEKYFDMKKNQCK
EGLDIYKKFLTRMTRISEFLKVAEQVGIDRGDIPDLSQAPSSLLDALEQHLASLEGKKIKDSTAASRATTLSNAVSSLASTGLSLTKVDE
REKQAALEEEQARLKALKEQRLKELAKKPHTSLTTAASPVSTSAGGIMTAPAIDIFSTPSSSNSTSKLPNDLLDLQQPTFHPSVHPMSTA

--------------------------------------------------------------
>65153_65153_7_PICALM-ME3_PICALM_chr11_85707869_ENST00000528398_ME3_chr11_86176242_ENST00000393324_length(transcript)=2468nt_BP=1291nt
TATGTGTTTCCTGTCCTATTCCACACCCTAGAGAATGAATACCGGCCAGCTAGTATCTAAATTTAGAATGGCAGCAACGTGTCGGGTTTT
CGGAGTAGAGATAAACAAAACCAGGTGACATTTCCAAGCCTCTCAAGGAAAGGGGGGAAAAAACCTTTCTGGGACTTAATTCAGTGCACA
AATGAGATGAATGTGAACATCCCACAGTTGGCAGACAGTTTATTTGAAAGAACTACTAATAGTAGTTGGGTGGTGGTCTTCAAATCTCTC
ATTACAACTCATCATTTGATGGTGTATGGAAATGAGCGTTTTATTCAGTATTTGGCTTCAAGAAACACGTTGTTTAACTTAAGCAATTTT
TTGGATAAAAGTGGATTGCAAGGATATGACATGTCTACATTTATTAGGCGGTATAGTAGATATTTAAATGAGAAAGCAGTTTCATACAGA
CAAGTTGCATTTGATTTCACAAAAGTGAAGAGAGGGGCTGATGGAGTTATGAGAACAATGAACACAGAAAAACTCCTAAAAACTGTACCA
ATTATTCAGAATCAGATGGATGCACTTCTTGATTTTAATGTTAATAGCAATGAACTTACAAATGGGGTAATAAATGCTGCCTTCATGCTC
CTGTTCAAAGATGCCATTAGACTGTTTGCAGCATACAATGAAGGAATTATTAATTTGTTGGAAAAATATTTTGATATGAAAAAGAACCAA
TGCAAAGAAGGTCTTGACATCTATAAGAAGTTCCTAACTAGGATGACAAGAATCTCAGAGTTCCTCAAAGTTGCAGAGCAAGTTGGAATT
GACAGAGGTGATATACCAGACCTTTCACAGGCCCCTAGCAGTCTTCTTGATGCTTTGGAACAACATTTAGCTTCCTTGGAAGGAAAGAAA
ATCAAAGATTCTACAGCTGCAAGCAGGGCAACTACACTTTCCAATGCAGTGTCTTCCCTGGCAAGCACTGGTCTATCTCTGACCAAAGTG
GATGAAAGGGAAAAGCAGGCAGCATTAGAGGAAGAACAGGCACGTTTGAAAGCTTTAAAGGAACAGCGCCTAAAAGAACTTGCAAAGAAA
CCTCATACCTCTTTAACAACTGCAGCCTCTCCTGTATCCACCTCAGCAGGAGGGATAATGACTGCACCAGCCATTGACATATTTTCTACC
CCTAGTTCTTCTAACAGCACATCAAAGCTGCCCAATGATCTGCTTGATTTGCAGCAGCCAACTTTTCACCCATCTGTACATCCTATGTCA
ACTGCTTCTCAGGTAGCAAGTACATGGGGAGGTTTGGAATAAATTGCCTCATCCAATTTGAAGACTTCGCCAATGCCAATGCCTTCCGCC
TGCTCAACAAATACCGTAACAAGTACTGCATGTTCAATGATGACATCCAAGGCACAGCCTCCGTTGCTGTGGCAGGGATCTTGGCTGCTC
TGCGAATCACCAAGAACAAGCTTTCCAATCACGTGTTTGTTTTCCAAGGTGCAGGCGAGGCAGCTATGGGCATTGCCCACCTCCTTGTCA
TGGCCCTAGAGAAAGAAGGTGTACCGAAGGCAGAGGCCACAAGAAAGATCTGGATGGTGGACTCTAAAGGGCTCATTGTCAAGGGGAGGA
GCCACCTGAACCATGAAAAGGAGATGTTTGCCCAAGACCATCCTGAAGTCAACTCCCTGGAGGAGGTGGTGAGGCTGGTGAAGCCCACAG
CCATCATAGGTGTTGCTGCCATCGCAGGAGCCTTCACGGAGCAGATTCTGAGGGACATGGCCTCCTTCCACGAGCGCCCTATCATCTTTG
CCCTGAGCAACCCCACCAGCAAGGCCGAGTGCACGGCTGAGAAGTGCTACCGGGTCACCGAGGGCCGAGGGATTTTTGCCAGTGGAAGTC
CTTTTAAGAGTGTGACTCTGGAAGATGGCAAGACCTTCATTCCTGGGCAGGGAAACAATGCTTACGTGTTCCCCGGGGTGGCACTGGGAG
TCATCGCCGGCGGGATCCGGCACATCCCAGATGAGATCTTCCTCCTGACAGCAGAGCAAATTGCCCAGGAAGTCTCTGAGCAGCATCTGT
CCCAGGGGAGACTCTACCCACCACTCAGCACCATCCGAGACGTGTCTTTGAGAATTGCCATCAAAGTTCTCGACTACGCGTACAAACACA
ACCTGGCTTCCTACTACCCAGAGCCTAAGGACAAGGAGGCTTTTGTAAGATCCCTGGTCTACACTCCAGACTATGACTCCTTTACACTGG
ACAGCTACACTTGGCCCAAGGAAGCCATGAATGTTCAGACGGTCTGAGGCAGTCTCAGAGGCTAGTATGGGGCTAGATGAAGCCCAGAGT
AACACCCACAATATAAATGGGTTCCAAAATGGCCCAAGTGAATCCTTGTCGCTGTGTTTTTTCTTTTAAACTTTCTGGTGTGAGAGGAGA

>65153_65153_7_PICALM-ME3_PICALM_chr11_85707869_ENST00000528398_ME3_chr11_86176242_ENST00000393324_length(amino acids)=371AA_BP=
MNVNIPQLADSLFERTTNSSWVVVFKSLITTHHLMVYGNERFIQYLASRNTLFNLSNFLDKSGLQGYDMSTFIRRYSRYLNEKAVSYRQV
AFDFTKVKRGADGVMRTMNTEKLLKTVPIIQNQMDALLDFNVNSNELTNGVINAAFMLLFKDAIRLFAAYNEGIINLLEKYFDMKKNQCK
EGLDIYKKFLTRMTRISEFLKVAEQVGIDRGDIPDLSQAPSSLLDALEQHLASLEGKKIKDSTAASRATTLSNAVSSLASTGLSLTKVDE
REKQAALEEEQARLKALKEQRLKELAKKPHTSLTTAASPVSTSAGGIMTAPAIDIFSTPSSSNSTSKLPNDLLDLQQPTFHPSVHPMSTA

--------------------------------------------------------------
>65153_65153_8_PICALM-ME3_PICALM_chr11_85707869_ENST00000528398_ME3_chr11_86176242_ENST00000543262_length(transcript)=2466nt_BP=1291nt
TATGTGTTTCCTGTCCTATTCCACACCCTAGAGAATGAATACCGGCCAGCTAGTATCTAAATTTAGAATGGCAGCAACGTGTCGGGTTTT
CGGAGTAGAGATAAACAAAACCAGGTGACATTTCCAAGCCTCTCAAGGAAAGGGGGGAAAAAACCTTTCTGGGACTTAATTCAGTGCACA
AATGAGATGAATGTGAACATCCCACAGTTGGCAGACAGTTTATTTGAAAGAACTACTAATAGTAGTTGGGTGGTGGTCTTCAAATCTCTC
ATTACAACTCATCATTTGATGGTGTATGGAAATGAGCGTTTTATTCAGTATTTGGCTTCAAGAAACACGTTGTTTAACTTAAGCAATTTT
TTGGATAAAAGTGGATTGCAAGGATATGACATGTCTACATTTATTAGGCGGTATAGTAGATATTTAAATGAGAAAGCAGTTTCATACAGA
CAAGTTGCATTTGATTTCACAAAAGTGAAGAGAGGGGCTGATGGAGTTATGAGAACAATGAACACAGAAAAACTCCTAAAAACTGTACCA
ATTATTCAGAATCAGATGGATGCACTTCTTGATTTTAATGTTAATAGCAATGAACTTACAAATGGGGTAATAAATGCTGCCTTCATGCTC
CTGTTCAAAGATGCCATTAGACTGTTTGCAGCATACAATGAAGGAATTATTAATTTGTTGGAAAAATATTTTGATATGAAAAAGAACCAA
TGCAAAGAAGGTCTTGACATCTATAAGAAGTTCCTAACTAGGATGACAAGAATCTCAGAGTTCCTCAAAGTTGCAGAGCAAGTTGGAATT
GACAGAGGTGATATACCAGACCTTTCACAGGCCCCTAGCAGTCTTCTTGATGCTTTGGAACAACATTTAGCTTCCTTGGAAGGAAAGAAA
ATCAAAGATTCTACAGCTGCAAGCAGGGCAACTACACTTTCCAATGCAGTGTCTTCCCTGGCAAGCACTGGTCTATCTCTGACCAAAGTG
GATGAAAGGGAAAAGCAGGCAGCATTAGAGGAAGAACAGGCACGTTTGAAAGCTTTAAAGGAACAGCGCCTAAAAGAACTTGCAAAGAAA
CCTCATACCTCTTTAACAACTGCAGCCTCTCCTGTATCCACCTCAGCAGGAGGGATAATGACTGCACCAGCCATTGACATATTTTCTACC
CCTAGTTCTTCTAACAGCACATCAAAGCTGCCCAATGATCTGCTTGATTTGCAGCAGCCAACTTTTCACCCATCTGTACATCCTATGTCA
ACTGCTTCTCAGGTAGCAAGTACATGGGGAGGTTTGGAATAAATTGCCTCATCCAATTTGAAGACTTCGCCAATGCCAATGCCTTCCGCC
TGCTCAACAAATACCGTAACAAGTACTGCATGTTCAATGATGACATCCAAGGCACAGCCTCCGTTGCTGTGGCAGGGATCTTGGCTGCTC
TGCGAATCACCAAGAACAAGCTTTCCAATCACGTGTTTGTTTTCCAAGGTGCAGGCGAGGCAGCTATGGGCATTGCCCACCTCCTTGTCA
TGGCCCTAGAGAAAGAAGGTGTACCGAAGGCAGAGGCCACAAGAAAGATCTGGATGGTGGACTCTAAAGGGCTCATTGTCAAGGGGAGGA
GCCACCTGAACCATGAAAAGGAGATGTTTGCCCAAGACCATCCTGAAGTCAACTCCCTGGAGGAGGTGGTGAGGCTGGTGAAGCCCACAG
CCATCATAGGTGTTGCTGCCATCGCAGGAGCCTTCACGGAGCAGATTCTGAGGGACATGGCCTCCTTCCACGAGCGCCCTATCATCTTTG
CCCTGAGCAACCCCACCAGCAAGGCCGAGTGCACGGCTGAGAAGTGCTACCGGGTCACCGAGGGCCGAGGGATTTTTGCCAGTGGAAGTC
CTTTTAAGAGTGTGACTCTGGAAGATGGCAAGACCTTCATTCCTGGGCAGGGAAACAATGCTTACGTGTTCCCCGGGGTGGCACTGGGAG
TCATCGCCGGCGGGATCCGGCACATCCCAGATGAGATCTTCCTCCTGACAGCAGAGCAAATTGCCCAGGAAGTCTCTGAGCAGCATCTGT
CCCAGGGGAGACTCTACCCACCACTCAGCACCATCCGAGACGTGTCTTTGAGAATTGCCATCAAAGTTCTCGACTACGCGTACAAACACA
ACCTGGCTTCCTACTACCCAGAGCCTAAGGACAAGGAGGCTTTTGTAAGATCCCTGGTCTACACTCCAGACTATGACTCCTTTACACTGG
ACAGCTACACTTGGCCCAAGGAAGCCATGAATGTTCAGACGGTCTGAGGCAGTCTCAGAGGCTAGTATGGGGCTAGATGAAGCCCAGAGT
AACACCCACAATATAAATGGGTTCCAAAATGGCCCAAGTGAATCCTTGTCGCTGTGTTTTTTCTTTTAAACTTTCTGGTGTGAGAGGAGA

>65153_65153_8_PICALM-ME3_PICALM_chr11_85707869_ENST00000528398_ME3_chr11_86176242_ENST00000543262_length(amino acids)=371AA_BP=
MNVNIPQLADSLFERTTNSSWVVVFKSLITTHHLMVYGNERFIQYLASRNTLFNLSNFLDKSGLQGYDMSTFIRRYSRYLNEKAVSYRQV
AFDFTKVKRGADGVMRTMNTEKLLKTVPIIQNQMDALLDFNVNSNELTNGVINAAFMLLFKDAIRLFAAYNEGIINLLEKYFDMKKNQCK
EGLDIYKKFLTRMTRISEFLKVAEQVGIDRGDIPDLSQAPSSLLDALEQHLASLEGKKIKDSTAASRATTLSNAVSSLASTGLSLTKVDE
REKQAALEEEQARLKALKEQRLKELAKKPHTSLTTAASPVSTSAGGIMTAPAIDIFSTPSSSNSTSKLPNDLLDLQQPTFHPSVHPMSTA

--------------------------------------------------------------
>65153_65153_9_PICALM-ME3_PICALM_chr11_85779693_ENST00000356360_ME3_chr11_86270865_ENST00000323418_length(transcript)=910nt_BP=130nt
ATGTCCGGCCAGAGCCTGACGGACCGAATCACTGCCGCCCAGCACAGTGTCACCGGCTCTGCCGTATCCAAGACAGTATGCAAGGCCACG
ACCCACGAGATCATGGGGCCCAAGAAAAAGCACCTGGACTATGGCCTTTACCCTTGAAGAAAGGCTGCAGCTTGGAATCCACGGCCTAAT
CCCGCCCTGCTTTCTGAGCCAGGACGTCCAGCTCCTCCGAATCATGAGATATTACGAGCGGCAGCAGAGTGACCTGGACAAGTACATCAT
TCTCATGACACTCCAAGACCGGAACGAGAAGCTCTTCTACCGAGTGCTGACTTCGGACGTGGAGAAGTTCATGCCAATCGTGTACACGCC
TACCGTGGGGCTGGCCTGTCAGCACTATGGCCTGACTTTCCGCAGGCCCCGTGGACTGTTCATCACCATTCATGACAAAGGTCATCTTGC
AACAATGCTGAATTCTTGGCCAGAAGACAATATTAAGGCCGTGGTGGTGACTGATGGGGAGCGCATCCTGGGCCTGGGAGACCTGGGCTG
CTACGGCATGGGCATCCCTGTGGGCAAGCTGGCCCTGTACACGGCATGCGGAGGGGTGAACCCGCAGCAGTGCCTCCCTGTGCTGCTGGA
CGTCGGCACCAACAATGAGGAGCTGCTCAGAGACCCTCTGTACATCGGCCTGAAACACCAGCGCGTGCACGGGAAGGCATACGATGACTT
GCTGGATGAGTTCATGCAGGCTGTGACAGACAAGTTTGGAATAAATTGCCTCATCCAATTTGAAGACTTCGCCAATGCCAATGCCTTCCG
CCTGCTCAACAAATACCGTAACAAGTACTGCATGTTCAATGATGACATCCAAGATGACTTCTCCAGAGGCCCAAAGAGGTCACAACTTTT

>65153_65153_9_PICALM-ME3_PICALM_chr11_85779693_ENST00000356360_ME3_chr11_86270865_ENST00000323418_length(amino acids)=293AA_BP=33
MPPSTVSPALPYPRQYARPRPTRSWGPRKSTWTMAFTLEERLQLGIHGLIPPCFLSQDVQLLRIMRYYERQQSDLDKYIILMTLQDRNEK
LFYRVLTSDVEKFMPIVYTPTVGLACQHYGLTFRRPRGLFITIHDKGHLATMLNSWPEDNIKAVVVTDGERILGLGDLGCYGMGIPVGKL
ALYTACGGVNPQQCLPVLLDVGTNNEELLRDPLYIGLKHQRVHGKAYDDLLDEFMQAVTDKFGINCLIQFEDFANANAFRLLNKYRNKYC

--------------------------------------------------------------
>65153_65153_10_PICALM-ME3_PICALM_chr11_85779693_ENST00000356360_ME3_chr11_86270865_ENST00000359636_length(transcript)=1933nt_BP=130nt
ATGTCCGGCCAGAGCCTGACGGACCGAATCACTGCCGCCCAGCACAGTGTCACCGGCTCTGCCGTATCCAAGACAGTATGCAAGGCCACG
ACCCACGAGATCATGGGGCCCAAGAAAAAGCACCTGGACTGGGATGGCCTTTACCCTTGAAGAAAGGCTGCAGCTTGGAATCCACGGCCT
AATCCCGCCCTGCTTTCTGAGCCAGGACGTCCAGCTCCTCCGAATCATGAGATATTACGAGCGGCAGCAGAGTGACCTGGACAAGTACAT
CATTCTCATGACACTCCAAGACCGGAACGAGAAGCTCTTCTACCGAGTGCTGACTTCGGACGTGGAGAAGTTCATGCCAATCGTGTACAC
GCCTACCGTGGGGCTGGCCTGTCAGCACTATGGCCTGACTTTCCGCAGGCCCCGTGGACTGTTCATCACCATTCATGACAAAGGTCATCT
TGCAACAATGCTGAATTCTTGGCCAGAAGACAATATTAAGGCCGTGGTGGTGACTGATGGGGAGCGCATCCTGGGCCTGGGAGACCTGGG
CTGCTACGGCATGGGCATCCCTGTGGGCAAGCTGGCCCTGTACACGGCATGCGGAGGGGTGAACCCGCAGCAGTGCCTCCCTGTGCTGCT
GGACGTCGGCACCAACAATGAGGAGCTGCTCAGAGACCCTCTGTACATCGGCCTGAAACACCAGCGCGTGCACGGGAAGGCATACGATGA
CTTGCTGGATGAGTTCATGCAGGCTGTGACAGACAAGTTTGGAATAAATTGCCTCATCCAATTTGAAGACTTCGCCAATGCCAATGCCTT
CCGCCTGCTCAACAAATACCGTAACAAGTACTGCATGTTCAATGATGACATCCAAGGCACAGCCTCCGTTGCTGTGGCAGGGATCTTGGC
TGCTCTGCGAATCACCAAGAACAAGCTTTCCAATCACGTGTTTGTTTTCCAAGGTGCAGGCGAGGCAGCTATGGGCATTGCCCACCTCCT
TGTCATGGCCCTAGAGAAAGAAGGTGTACCGAAGGCAGAGGCCACAAGAAAGATCTGGATGGTGGACTCTAAAGGGCTCATTGTCAAGGG
GAGGAGCCACCTGAACCATGAAAAGGAGATGTTTGCCCAAGACCATCCTGAAGTCAACTCCCTGGAGGAGGTGGTGAGGCTGGTGAAGCC
CACAGCCATCATAGGTGTTGCTGCCATCGCAGGAGCCTTCACGGAGCAGATTCTGAGGGACATGGCCTCCTTCCACGAGCGCCCTATCAT
CTTTGCCCTGAGCAACCCCACCAGCAAGGCCGAGTGCACGGCTGAGAAGTGCTACCGGGTCACCGAGGGCCGAGGGATTTTTGCCAGTGG
AAGTCCTTTTAAGAGTGTGACTCTGGAAGATGGCAAGACCTTCATTCCTGGGCAGGGAAACAATGCTTACGTGTTCCCCGGGGTGGCACT
GGGAGTCATCGCCGGCGGGATCCGGCACATCCCAGATGAGATCTTCCTCCTGACAGCAGAGCAAATTGCCCAGGAAGTCTCTGAGCAGCA
TCTGTCCCAGGGGAGACTCTACCCACCACTCAGCACCATCCGAGACGTGTCTTTGAGAATTGCCATCAAAGTTCTCGACTACGCGTACAA
ACACAACCTGGCTTCCTACTACCCAGAGCCTAAGGACAAGGAGGCTTTTGTAAGATCCCTGGTCTACACTCCAGACTATGACTCCTTTAC
ACTGGACAGCTACACTTGGCCCAAGGAAGCCATGAATGTTCAGACGGTCTGAGGCAGTCTCAGAGGCTAGTATGGGGCTAGATGAAGCCC
AGAGTAACACCCACAATATAAATGGGTTCCAAAATGGCCCAAGTGAATCCTTGTCGCTGTGTTTTTTCTTTTAAACTTTCTGGTGTGAGA

>65153_65153_10_PICALM-ME3_PICALM_chr11_85779693_ENST00000356360_ME3_chr11_86270865_ENST00000359636_length(amino acids)=576AA_BP=33
MPPSTVSPALPYPRQYARPRPTRSWGPRKSTWTGMAFTLEERLQLGIHGLIPPCFLSQDVQLLRIMRYYERQQSDLDKYIILMTLQDRNE
KLFYRVLTSDVEKFMPIVYTPTVGLACQHYGLTFRRPRGLFITIHDKGHLATMLNSWPEDNIKAVVVTDGERILGLGDLGCYGMGIPVGK
LALYTACGGVNPQQCLPVLLDVGTNNEELLRDPLYIGLKHQRVHGKAYDDLLDEFMQAVTDKFGINCLIQFEDFANANAFRLLNKYRNKY
CMFNDDIQGTASVAVAGILAALRITKNKLSNHVFVFQGAGEAAMGIAHLLVMALEKEGVPKAEATRKIWMVDSKGLIVKGRSHLNHEKEM
FAQDHPEVNSLEEVVRLVKPTAIIGVAAIAGAFTEQILRDMASFHERPIIFALSNPTSKAECTAEKCYRVTEGRGIFASGSPFKSVTLED
GKTFIPGQGNNAYVFPGVALGVIAGGIRHIPDEIFLLTAEQIAQEVSEQHLSQGRLYPPLSTIRDVSLRIAIKVLDYAYKHNLASYYPEP

--------------------------------------------------------------
>65153_65153_11_PICALM-ME3_PICALM_chr11_85779693_ENST00000356360_ME3_chr11_86270865_ENST00000393324_length(transcript)=1933nt_BP=130nt
ATGTCCGGCCAGAGCCTGACGGACCGAATCACTGCCGCCCAGCACAGTGTCACCGGCTCTGCCGTATCCAAGACAGTATGCAAGGCCACG
ACCCACGAGATCATGGGGCCCAAGAAAAAGCACCTGGACTGGGATGGCCTTTACCCTTGAAGAAAGGCTGCAGCTTGGAATCCACGGCCT
AATCCCGCCCTGCTTTCTGAGCCAGGACGTCCAGCTCCTCCGAATCATGAGATATTACGAGCGGCAGCAGAGTGACCTGGACAAGTACAT
CATTCTCATGACACTCCAAGACCGGAACGAGAAGCTCTTCTACCGAGTGCTGACTTCGGACGTGGAGAAGTTCATGCCAATCGTGTACAC
GCCTACCGTGGGGCTGGCCTGTCAGCACTATGGCCTGACTTTCCGCAGGCCCCGTGGACTGTTCATCACCATTCATGACAAAGGTCATCT
TGCAACAATGCTGAATTCTTGGCCAGAAGACAATATTAAGGCCGTGGTGGTGACTGATGGGGAGCGCATCCTGGGCCTGGGAGACCTGGG
CTGCTACGGCATGGGCATCCCTGTGGGCAAGCTGGCCCTGTACACGGCATGCGGAGGGGTGAACCCGCAGCAGTGCCTCCCTGTGCTGCT
GGACGTCGGCACCAACAATGAGGAGCTGCTCAGAGACCCTCTGTACATCGGCCTGAAACACCAGCGCGTGCACGGGAAGGCATACGATGA
CTTGCTGGATGAGTTCATGCAGGCTGTGACAGACAAGTTTGGAATAAATTGCCTCATCCAATTTGAAGACTTCGCCAATGCCAATGCCTT
CCGCCTGCTCAACAAATACCGTAACAAGTACTGCATGTTCAATGATGACATCCAAGGCACAGCCTCCGTTGCTGTGGCAGGGATCTTGGC
TGCTCTGCGAATCACCAAGAACAAGCTTTCCAATCACGTGTTTGTTTTCCAAGGTGCAGGCGAGGCAGCTATGGGCATTGCCCACCTCCT
TGTCATGGCCCTAGAGAAAGAAGGTGTACCGAAGGCAGAGGCCACAAGAAAGATCTGGATGGTGGACTCTAAAGGGCTCATTGTCAAGGG
GAGGAGCCACCTGAACCATGAAAAGGAGATGTTTGCCCAAGACCATCCTGAAGTCAACTCCCTGGAGGAGGTGGTGAGGCTGGTGAAGCC
CACAGCCATCATAGGTGTTGCTGCCATCGCAGGAGCCTTCACGGAGCAGATTCTGAGGGACATGGCCTCCTTCCACGAGCGCCCTATCAT
CTTTGCCCTGAGCAACCCCACCAGCAAGGCCGAGTGCACGGCTGAGAAGTGCTACCGGGTCACCGAGGGCCGAGGGATTTTTGCCAGTGG
AAGTCCTTTTAAGAGTGTGACTCTGGAAGATGGCAAGACCTTCATTCCTGGGCAGGGAAACAATGCTTACGTGTTCCCCGGGGTGGCACT
GGGAGTCATCGCCGGCGGGATCCGGCACATCCCAGATGAGATCTTCCTCCTGACAGCAGAGCAAATTGCCCAGGAAGTCTCTGAGCAGCA
TCTGTCCCAGGGGAGACTCTACCCACCACTCAGCACCATCCGAGACGTGTCTTTGAGAATTGCCATCAAAGTTCTCGACTACGCGTACAA
ACACAACCTGGCTTCCTACTACCCAGAGCCTAAGGACAAGGAGGCTTTTGTAAGATCCCTGGTCTACACTCCAGACTATGACTCCTTTAC
ACTGGACAGCTACACTTGGCCCAAGGAAGCCATGAATGTTCAGACGGTCTGAGGCAGTCTCAGAGGCTAGTATGGGGCTAGATGAAGCCC
AGAGTAACACCCACAATATAAATGGGTTCCAAAATGGCCCAAGTGAATCCTTGTCGCTGTGTTTTTTCTTTTAAACTTTCTGGTGTGAGA

>65153_65153_11_PICALM-ME3_PICALM_chr11_85779693_ENST00000356360_ME3_chr11_86270865_ENST00000393324_length(amino acids)=576AA_BP=33
MPPSTVSPALPYPRQYARPRPTRSWGPRKSTWTGMAFTLEERLQLGIHGLIPPCFLSQDVQLLRIMRYYERQQSDLDKYIILMTLQDRNE
KLFYRVLTSDVEKFMPIVYTPTVGLACQHYGLTFRRPRGLFITIHDKGHLATMLNSWPEDNIKAVVVTDGERILGLGDLGCYGMGIPVGK
LALYTACGGVNPQQCLPVLLDVGTNNEELLRDPLYIGLKHQRVHGKAYDDLLDEFMQAVTDKFGINCLIQFEDFANANAFRLLNKYRNKY
CMFNDDIQGTASVAVAGILAALRITKNKLSNHVFVFQGAGEAAMGIAHLLVMALEKEGVPKAEATRKIWMVDSKGLIVKGRSHLNHEKEM
FAQDHPEVNSLEEVVRLVKPTAIIGVAAIAGAFTEQILRDMASFHERPIIFALSNPTSKAECTAEKCYRVTEGRGIFASGSPFKSVTLED
GKTFIPGQGNNAYVFPGVALGVIAGGIRHIPDEIFLLTAEQIAQEVSEQHLSQGRLYPPLSTIRDVSLRIAIKVLDYAYKHNLASYYPEP

--------------------------------------------------------------
>65153_65153_12_PICALM-ME3_PICALM_chr11_85779693_ENST00000356360_ME3_chr11_86270865_ENST00000543262_length(transcript)=1931nt_BP=130nt
ATGTCCGGCCAGAGCCTGACGGACCGAATCACTGCCGCCCAGCACAGTGTCACCGGCTCTGCCGTATCCAAGACAGTATGCAAGGCCACG
ACCCACGAGATCATGGGGCCCAAGAAAAAGCACCTGGACTGGGATGGCCTTTACCCTTGAAGAAAGGCTGCAGCTTGGAATCCACGGCCT
AATCCCGCCCTGCTTTCTGAGCCAGGACGTCCAGCTCCTCCGAATCATGAGATATTACGAGCGGCAGCAGAGTGACCTGGACAAGTACAT
CATTCTCATGACACTCCAAGACCGGAACGAGAAGCTCTTCTACCGAGTGCTGACTTCGGACGTGGAGAAGTTCATGCCAATCGTGTACAC
GCCTACCGTGGGGCTGGCCTGTCAGCACTATGGCCTGACTTTCCGCAGGCCCCGTGGACTGTTCATCACCATTCATGACAAAGGTCATCT
TGCAACAATGCTGAATTCTTGGCCAGAAGACAATATTAAGGCCGTGGTGGTGACTGATGGGGAGCGCATCCTGGGCCTGGGAGACCTGGG
CTGCTACGGCATGGGCATCCCTGTGGGCAAGCTGGCCCTGTACACGGCATGCGGAGGGGTGAACCCGCAGCAGTGCCTCCCTGTGCTGCT
GGACGTCGGCACCAACAATGAGGAGCTGCTCAGAGACCCTCTGTACATCGGCCTGAAACACCAGCGCGTGCACGGGAAGGCATACGATGA
CTTGCTGGATGAGTTCATGCAGGCTGTGACAGACAAGTTTGGAATAAATTGCCTCATCCAATTTGAAGACTTCGCCAATGCCAATGCCTT
CCGCCTGCTCAACAAATACCGTAACAAGTACTGCATGTTCAATGATGACATCCAAGGCACAGCCTCCGTTGCTGTGGCAGGGATCTTGGC
TGCTCTGCGAATCACCAAGAACAAGCTTTCCAATCACGTGTTTGTTTTCCAAGGTGCAGGCGAGGCAGCTATGGGCATTGCCCACCTCCT
TGTCATGGCCCTAGAGAAAGAAGGTGTACCGAAGGCAGAGGCCACAAGAAAGATCTGGATGGTGGACTCTAAAGGGCTCATTGTCAAGGG
GAGGAGCCACCTGAACCATGAAAAGGAGATGTTTGCCCAAGACCATCCTGAAGTCAACTCCCTGGAGGAGGTGGTGAGGCTGGTGAAGCC
CACAGCCATCATAGGTGTTGCTGCCATCGCAGGAGCCTTCACGGAGCAGATTCTGAGGGACATGGCCTCCTTCCACGAGCGCCCTATCAT
CTTTGCCCTGAGCAACCCCACCAGCAAGGCCGAGTGCACGGCTGAGAAGTGCTACCGGGTCACCGAGGGCCGAGGGATTTTTGCCAGTGG
AAGTCCTTTTAAGAGTGTGACTCTGGAAGATGGCAAGACCTTCATTCCTGGGCAGGGAAACAATGCTTACGTGTTCCCCGGGGTGGCACT
GGGAGTCATCGCCGGCGGGATCCGGCACATCCCAGATGAGATCTTCCTCCTGACAGCAGAGCAAATTGCCCAGGAAGTCTCTGAGCAGCA
TCTGTCCCAGGGGAGACTCTACCCACCACTCAGCACCATCCGAGACGTGTCTTTGAGAATTGCCATCAAAGTTCTCGACTACGCGTACAA
ACACAACCTGGCTTCCTACTACCCAGAGCCTAAGGACAAGGAGGCTTTTGTAAGATCCCTGGTCTACACTCCAGACTATGACTCCTTTAC
ACTGGACAGCTACACTTGGCCCAAGGAAGCCATGAATGTTCAGACGGTCTGAGGCAGTCTCAGAGGCTAGTATGGGGCTAGATGAAGCCC
AGAGTAACACCCACAATATAAATGGGTTCCAAAATGGCCCAAGTGAATCCTTGTCGCTGTGTTTTTTCTTTTAAACTTTCTGGTGTGAGA

>65153_65153_12_PICALM-ME3_PICALM_chr11_85779693_ENST00000356360_ME3_chr11_86270865_ENST00000543262_length(amino acids)=576AA_BP=33
MPPSTVSPALPYPRQYARPRPTRSWGPRKSTWTGMAFTLEERLQLGIHGLIPPCFLSQDVQLLRIMRYYERQQSDLDKYIILMTLQDRNE
KLFYRVLTSDVEKFMPIVYTPTVGLACQHYGLTFRRPRGLFITIHDKGHLATMLNSWPEDNIKAVVVTDGERILGLGDLGCYGMGIPVGK
LALYTACGGVNPQQCLPVLLDVGTNNEELLRDPLYIGLKHQRVHGKAYDDLLDEFMQAVTDKFGINCLIQFEDFANANAFRLLNKYRNKY
CMFNDDIQGTASVAVAGILAALRITKNKLSNHVFVFQGAGEAAMGIAHLLVMALEKEGVPKAEATRKIWMVDSKGLIVKGRSHLNHEKEM
FAQDHPEVNSLEEVVRLVKPTAIIGVAAIAGAFTEQILRDMASFHERPIIFALSNPTSKAECTAEKCYRVTEGRGIFASGSPFKSVTLED
GKTFIPGQGNNAYVFPGVALGVIAGGIRHIPDEIFLLTAEQIAQEVSEQHLSQGRLYPPLSTIRDVSLRIAIKVLDYAYKHNLASYYPEP

--------------------------------------------------------------
>65153_65153_13_PICALM-ME3_PICALM_chr11_85779693_ENST00000393346_ME3_chr11_86270865_ENST00000323418_length(transcript)=1059nt_BP=279nt
GCGCGGCCCCGAACCGCGCCCCAGGCCGGCAGGCGGGGAAGGAGCCGGTGGGGGTAGGGGGTGCGGTGGGGGGTGGGGACCCTCCGGCTC
TTGGGGGTCCCAGTCCCCGCCGGCTGCTGAGCGGGTGGGGTGGTGGAGGAGCTGCAGAGATGTCCGGCCAGAGCCTGACGGACCGAATCA
CTGCCGCCCAGCACAGTGTCACCGGCTCTGCCGTATCCAAGACAGTATGCAAGGCCACGACCCACGAGATCATGGGGCCCAAGAAAAAGC
ACCTGGACTATGGCCTTTACCCTTGAAGAAAGGCTGCAGCTTGGAATCCACGGCCTAATCCCGCCCTGCTTTCTGAGCCAGGACGTCCAG
CTCCTCCGAATCATGAGATATTACGAGCGGCAGCAGAGTGACCTGGACAAGTACATCATTCTCATGACACTCCAAGACCGGAACGAGAAG
CTCTTCTACCGAGTGCTGACTTCGGACGTGGAGAAGTTCATGCCAATCGTGTACACGCCTACCGTGGGGCTGGCCTGTCAGCACTATGGC
CTGACTTTCCGCAGGCCCCGTGGACTGTTCATCACCATTCATGACAAAGGTCATCTTGCAACAATGCTGAATTCTTGGCCAGAAGACAAT
ATTAAGGCCGTGGTGGTGACTGATGGGGAGCGCATCCTGGGCCTGGGAGACCTGGGCTGCTACGGCATGGGCATCCCTGTGGGCAAGCTG
GCCCTGTACACGGCATGCGGAGGGGTGAACCCGCAGCAGTGCCTCCCTGTGCTGCTGGACGTCGGCACCAACAATGAGGAGCTGCTCAGA
GACCCTCTGTACATCGGCCTGAAACACCAGCGCGTGCACGGGAAGGCATACGATGACTTGCTGGATGAGTTCATGCAGGCTGTGACAGAC
AAGTTTGGAATAAATTGCCTCATCCAATTTGAAGACTTCGCCAATGCCAATGCCTTCCGCCTGCTCAACAAATACCGTAACAAGTACTGC

>65153_65153_13_PICALM-ME3_PICALM_chr11_85779693_ENST00000393346_ME3_chr11_86270865_ENST00000323418_length(amino acids)=292AA_BP=33
MPPSTVSPALPYPRQYARPRPTRSWGPRKSTWTMAFTLEERLQLGIHGLIPPCFLSQDVQLLRIMRYYERQQSDLDKYIILMTLQDRNEK
LFYRVLTSDVEKFMPIVYTPTVGLACQHYGLTFRRPRGLFITIHDKGHLATMLNSWPEDNIKAVVVTDGERILGLGDLGCYGMGIPVGKL
ALYTACGGVNPQQCLPVLLDVGTNNEELLRDPLYIGLKHQRVHGKAYDDLLDEFMQAVTDKFGINCLIQFEDFANANAFRLLNKYRNKYC

--------------------------------------------------------------
>65153_65153_14_PICALM-ME3_PICALM_chr11_85779693_ENST00000393346_ME3_chr11_86270865_ENST00000359636_length(transcript)=2082nt_BP=279nt
GCGCGGCCCCGAACCGCGCCCCAGGCCGGCAGGCGGGGAAGGAGCCGGTGGGGGTAGGGGGTGCGGTGGGGGGTGGGGACCCTCCGGCTC
TTGGGGGTCCCAGTCCCCGCCGGCTGCTGAGCGGGTGGGGTGGTGGAGGAGCTGCAGAGATGTCCGGCCAGAGCCTGACGGACCGAATCA
CTGCCGCCCAGCACAGTGTCACCGGCTCTGCCGTATCCAAGACAGTATGCAAGGCCACGACCCACGAGATCATGGGGCCCAAGAAAAAGC
ACCTGGACTGGGATGGCCTTTACCCTTGAAGAAAGGCTGCAGCTTGGAATCCACGGCCTAATCCCGCCCTGCTTTCTGAGCCAGGACGTC
CAGCTCCTCCGAATCATGAGATATTACGAGCGGCAGCAGAGTGACCTGGACAAGTACATCATTCTCATGACACTCCAAGACCGGAACGAG
AAGCTCTTCTACCGAGTGCTGACTTCGGACGTGGAGAAGTTCATGCCAATCGTGTACACGCCTACCGTGGGGCTGGCCTGTCAGCACTAT
GGCCTGACTTTCCGCAGGCCCCGTGGACTGTTCATCACCATTCATGACAAAGGTCATCTTGCAACAATGCTGAATTCTTGGCCAGAAGAC
AATATTAAGGCCGTGGTGGTGACTGATGGGGAGCGCATCCTGGGCCTGGGAGACCTGGGCTGCTACGGCATGGGCATCCCTGTGGGCAAG
CTGGCCCTGTACACGGCATGCGGAGGGGTGAACCCGCAGCAGTGCCTCCCTGTGCTGCTGGACGTCGGCACCAACAATGAGGAGCTGCTC
AGAGACCCTCTGTACATCGGCCTGAAACACCAGCGCGTGCACGGGAAGGCATACGATGACTTGCTGGATGAGTTCATGCAGGCTGTGACA
GACAAGTTTGGAATAAATTGCCTCATCCAATTTGAAGACTTCGCCAATGCCAATGCCTTCCGCCTGCTCAACAAATACCGTAACAAGTAC
TGCATGTTCAATGATGACATCCAAGGCACAGCCTCCGTTGCTGTGGCAGGGATCTTGGCTGCTCTGCGAATCACCAAGAACAAGCTTTCC
AATCACGTGTTTGTTTTCCAAGGTGCAGGCGAGGCAGCTATGGGCATTGCCCACCTCCTTGTCATGGCCCTAGAGAAAGAAGGTGTACCG
AAGGCAGAGGCCACAAGAAAGATCTGGATGGTGGACTCTAAAGGGCTCATTGTCAAGGGGAGGAGCCACCTGAACCATGAAAAGGAGATG
TTTGCCCAAGACCATCCTGAAGTCAACTCCCTGGAGGAGGTGGTGAGGCTGGTGAAGCCCACAGCCATCATAGGTGTTGCTGCCATCGCA
GGAGCCTTCACGGAGCAGATTCTGAGGGACATGGCCTCCTTCCACGAGCGCCCTATCATCTTTGCCCTGAGCAACCCCACCAGCAAGGCC
GAGTGCACGGCTGAGAAGTGCTACCGGGTCACCGAGGGCCGAGGGATTTTTGCCAGTGGAAGTCCTTTTAAGAGTGTGACTCTGGAAGAT
GGCAAGACCTTCATTCCTGGGCAGGGAAACAATGCTTACGTGTTCCCCGGGGTGGCACTGGGAGTCATCGCCGGCGGGATCCGGCACATC
CCAGATGAGATCTTCCTCCTGACAGCAGAGCAAATTGCCCAGGAAGTCTCTGAGCAGCATCTGTCCCAGGGGAGACTCTACCCACCACTC
AGCACCATCCGAGACGTGTCTTTGAGAATTGCCATCAAAGTTCTCGACTACGCGTACAAACACAACCTGGCTTCCTACTACCCAGAGCCT
AAGGACAAGGAGGCTTTTGTAAGATCCCTGGTCTACACTCCAGACTATGACTCCTTTACACTGGACAGCTACACTTGGCCCAAGGAAGCC
ATGAATGTTCAGACGGTCTGAGGCAGTCTCAGAGGCTAGTATGGGGCTAGATGAAGCCCAGAGTAACACCCACAATATAAATGGGTTCCA
AAATGGCCCAAGTGAATCCTTGTCGCTGTGTTTTTTCTTTTAAACTTTCTGGTGTGAGAGGAGATGCCAAGGCATACAGTGAATAAAAGC

>65153_65153_14_PICALM-ME3_PICALM_chr11_85779693_ENST00000393346_ME3_chr11_86270865_ENST00000359636_length(amino acids)=576AA_BP=33
MPPSTVSPALPYPRQYARPRPTRSWGPRKSTWTGMAFTLEERLQLGIHGLIPPCFLSQDVQLLRIMRYYERQQSDLDKYIILMTLQDRNE
KLFYRVLTSDVEKFMPIVYTPTVGLACQHYGLTFRRPRGLFITIHDKGHLATMLNSWPEDNIKAVVVTDGERILGLGDLGCYGMGIPVGK
LALYTACGGVNPQQCLPVLLDVGTNNEELLRDPLYIGLKHQRVHGKAYDDLLDEFMQAVTDKFGINCLIQFEDFANANAFRLLNKYRNKY
CMFNDDIQGTASVAVAGILAALRITKNKLSNHVFVFQGAGEAAMGIAHLLVMALEKEGVPKAEATRKIWMVDSKGLIVKGRSHLNHEKEM
FAQDHPEVNSLEEVVRLVKPTAIIGVAAIAGAFTEQILRDMASFHERPIIFALSNPTSKAECTAEKCYRVTEGRGIFASGSPFKSVTLED
GKTFIPGQGNNAYVFPGVALGVIAGGIRHIPDEIFLLTAEQIAQEVSEQHLSQGRLYPPLSTIRDVSLRIAIKVLDYAYKHNLASYYPEP

--------------------------------------------------------------
>65153_65153_15_PICALM-ME3_PICALM_chr11_85779693_ENST00000393346_ME3_chr11_86270865_ENST00000393324_length(transcript)=2082nt_BP=279nt
GCGCGGCCCCGAACCGCGCCCCAGGCCGGCAGGCGGGGAAGGAGCCGGTGGGGGTAGGGGGTGCGGTGGGGGGTGGGGACCCTCCGGCTC
TTGGGGGTCCCAGTCCCCGCCGGCTGCTGAGCGGGTGGGGTGGTGGAGGAGCTGCAGAGATGTCCGGCCAGAGCCTGACGGACCGAATCA
CTGCCGCCCAGCACAGTGTCACCGGCTCTGCCGTATCCAAGACAGTATGCAAGGCCACGACCCACGAGATCATGGGGCCCAAGAAAAAGC
ACCTGGACTGGGATGGCCTTTACCCTTGAAGAAAGGCTGCAGCTTGGAATCCACGGCCTAATCCCGCCCTGCTTTCTGAGCCAGGACGTC
CAGCTCCTCCGAATCATGAGATATTACGAGCGGCAGCAGAGTGACCTGGACAAGTACATCATTCTCATGACACTCCAAGACCGGAACGAG
AAGCTCTTCTACCGAGTGCTGACTTCGGACGTGGAGAAGTTCATGCCAATCGTGTACACGCCTACCGTGGGGCTGGCCTGTCAGCACTAT
GGCCTGACTTTCCGCAGGCCCCGTGGACTGTTCATCACCATTCATGACAAAGGTCATCTTGCAACAATGCTGAATTCTTGGCCAGAAGAC
AATATTAAGGCCGTGGTGGTGACTGATGGGGAGCGCATCCTGGGCCTGGGAGACCTGGGCTGCTACGGCATGGGCATCCCTGTGGGCAAG
CTGGCCCTGTACACGGCATGCGGAGGGGTGAACCCGCAGCAGTGCCTCCCTGTGCTGCTGGACGTCGGCACCAACAATGAGGAGCTGCTC
AGAGACCCTCTGTACATCGGCCTGAAACACCAGCGCGTGCACGGGAAGGCATACGATGACTTGCTGGATGAGTTCATGCAGGCTGTGACA
GACAAGTTTGGAATAAATTGCCTCATCCAATTTGAAGACTTCGCCAATGCCAATGCCTTCCGCCTGCTCAACAAATACCGTAACAAGTAC
TGCATGTTCAATGATGACATCCAAGGCACAGCCTCCGTTGCTGTGGCAGGGATCTTGGCTGCTCTGCGAATCACCAAGAACAAGCTTTCC
AATCACGTGTTTGTTTTCCAAGGTGCAGGCGAGGCAGCTATGGGCATTGCCCACCTCCTTGTCATGGCCCTAGAGAAAGAAGGTGTACCG
AAGGCAGAGGCCACAAGAAAGATCTGGATGGTGGACTCTAAAGGGCTCATTGTCAAGGGGAGGAGCCACCTGAACCATGAAAAGGAGATG
TTTGCCCAAGACCATCCTGAAGTCAACTCCCTGGAGGAGGTGGTGAGGCTGGTGAAGCCCACAGCCATCATAGGTGTTGCTGCCATCGCA
GGAGCCTTCACGGAGCAGATTCTGAGGGACATGGCCTCCTTCCACGAGCGCCCTATCATCTTTGCCCTGAGCAACCCCACCAGCAAGGCC
GAGTGCACGGCTGAGAAGTGCTACCGGGTCACCGAGGGCCGAGGGATTTTTGCCAGTGGAAGTCCTTTTAAGAGTGTGACTCTGGAAGAT
GGCAAGACCTTCATTCCTGGGCAGGGAAACAATGCTTACGTGTTCCCCGGGGTGGCACTGGGAGTCATCGCCGGCGGGATCCGGCACATC
CCAGATGAGATCTTCCTCCTGACAGCAGAGCAAATTGCCCAGGAAGTCTCTGAGCAGCATCTGTCCCAGGGGAGACTCTACCCACCACTC
AGCACCATCCGAGACGTGTCTTTGAGAATTGCCATCAAAGTTCTCGACTACGCGTACAAACACAACCTGGCTTCCTACTACCCAGAGCCT
AAGGACAAGGAGGCTTTTGTAAGATCCCTGGTCTACACTCCAGACTATGACTCCTTTACACTGGACAGCTACACTTGGCCCAAGGAAGCC
ATGAATGTTCAGACGGTCTGAGGCAGTCTCAGAGGCTAGTATGGGGCTAGATGAAGCCCAGAGTAACACCCACAATATAAATGGGTTCCA
AAATGGCCCAAGTGAATCCTTGTCGCTGTGTTTTTTCTTTTAAACTTTCTGGTGTGAGAGGAGATGCCAAGGCATACAGTGAATAAAAGC

>65153_65153_15_PICALM-ME3_PICALM_chr11_85779693_ENST00000393346_ME3_chr11_86270865_ENST00000393324_length(amino acids)=576AA_BP=33
MPPSTVSPALPYPRQYARPRPTRSWGPRKSTWTGMAFTLEERLQLGIHGLIPPCFLSQDVQLLRIMRYYERQQSDLDKYIILMTLQDRNE
KLFYRVLTSDVEKFMPIVYTPTVGLACQHYGLTFRRPRGLFITIHDKGHLATMLNSWPEDNIKAVVVTDGERILGLGDLGCYGMGIPVGK
LALYTACGGVNPQQCLPVLLDVGTNNEELLRDPLYIGLKHQRVHGKAYDDLLDEFMQAVTDKFGINCLIQFEDFANANAFRLLNKYRNKY
CMFNDDIQGTASVAVAGILAALRITKNKLSNHVFVFQGAGEAAMGIAHLLVMALEKEGVPKAEATRKIWMVDSKGLIVKGRSHLNHEKEM
FAQDHPEVNSLEEVVRLVKPTAIIGVAAIAGAFTEQILRDMASFHERPIIFALSNPTSKAECTAEKCYRVTEGRGIFASGSPFKSVTLED
GKTFIPGQGNNAYVFPGVALGVIAGGIRHIPDEIFLLTAEQIAQEVSEQHLSQGRLYPPLSTIRDVSLRIAIKVLDYAYKHNLASYYPEP

--------------------------------------------------------------
>65153_65153_16_PICALM-ME3_PICALM_chr11_85779693_ENST00000393346_ME3_chr11_86270865_ENST00000543262_length(transcript)=2080nt_BP=279nt
GCGCGGCCCCGAACCGCGCCCCAGGCCGGCAGGCGGGGAAGGAGCCGGTGGGGGTAGGGGGTGCGGTGGGGGGTGGGGACCCTCCGGCTC
TTGGGGGTCCCAGTCCCCGCCGGCTGCTGAGCGGGTGGGGTGGTGGAGGAGCTGCAGAGATGTCCGGCCAGAGCCTGACGGACCGAATCA
CTGCCGCCCAGCACAGTGTCACCGGCTCTGCCGTATCCAAGACAGTATGCAAGGCCACGACCCACGAGATCATGGGGCCCAAGAAAAAGC
ACCTGGACTGGGATGGCCTTTACCCTTGAAGAAAGGCTGCAGCTTGGAATCCACGGCCTAATCCCGCCCTGCTTTCTGAGCCAGGACGTC
CAGCTCCTCCGAATCATGAGATATTACGAGCGGCAGCAGAGTGACCTGGACAAGTACATCATTCTCATGACACTCCAAGACCGGAACGAG
AAGCTCTTCTACCGAGTGCTGACTTCGGACGTGGAGAAGTTCATGCCAATCGTGTACACGCCTACCGTGGGGCTGGCCTGTCAGCACTAT
GGCCTGACTTTCCGCAGGCCCCGTGGACTGTTCATCACCATTCATGACAAAGGTCATCTTGCAACAATGCTGAATTCTTGGCCAGAAGAC
AATATTAAGGCCGTGGTGGTGACTGATGGGGAGCGCATCCTGGGCCTGGGAGACCTGGGCTGCTACGGCATGGGCATCCCTGTGGGCAAG
CTGGCCCTGTACACGGCATGCGGAGGGGTGAACCCGCAGCAGTGCCTCCCTGTGCTGCTGGACGTCGGCACCAACAATGAGGAGCTGCTC
AGAGACCCTCTGTACATCGGCCTGAAACACCAGCGCGTGCACGGGAAGGCATACGATGACTTGCTGGATGAGTTCATGCAGGCTGTGACA
GACAAGTTTGGAATAAATTGCCTCATCCAATTTGAAGACTTCGCCAATGCCAATGCCTTCCGCCTGCTCAACAAATACCGTAACAAGTAC
TGCATGTTCAATGATGACATCCAAGGCACAGCCTCCGTTGCTGTGGCAGGGATCTTGGCTGCTCTGCGAATCACCAAGAACAAGCTTTCC
AATCACGTGTTTGTTTTCCAAGGTGCAGGCGAGGCAGCTATGGGCATTGCCCACCTCCTTGTCATGGCCCTAGAGAAAGAAGGTGTACCG
AAGGCAGAGGCCACAAGAAAGATCTGGATGGTGGACTCTAAAGGGCTCATTGTCAAGGGGAGGAGCCACCTGAACCATGAAAAGGAGATG
TTTGCCCAAGACCATCCTGAAGTCAACTCCCTGGAGGAGGTGGTGAGGCTGGTGAAGCCCACAGCCATCATAGGTGTTGCTGCCATCGCA
GGAGCCTTCACGGAGCAGATTCTGAGGGACATGGCCTCCTTCCACGAGCGCCCTATCATCTTTGCCCTGAGCAACCCCACCAGCAAGGCC
GAGTGCACGGCTGAGAAGTGCTACCGGGTCACCGAGGGCCGAGGGATTTTTGCCAGTGGAAGTCCTTTTAAGAGTGTGACTCTGGAAGAT
GGCAAGACCTTCATTCCTGGGCAGGGAAACAATGCTTACGTGTTCCCCGGGGTGGCACTGGGAGTCATCGCCGGCGGGATCCGGCACATC
CCAGATGAGATCTTCCTCCTGACAGCAGAGCAAATTGCCCAGGAAGTCTCTGAGCAGCATCTGTCCCAGGGGAGACTCTACCCACCACTC
AGCACCATCCGAGACGTGTCTTTGAGAATTGCCATCAAAGTTCTCGACTACGCGTACAAACACAACCTGGCTTCCTACTACCCAGAGCCT
AAGGACAAGGAGGCTTTTGTAAGATCCCTGGTCTACACTCCAGACTATGACTCCTTTACACTGGACAGCTACACTTGGCCCAAGGAAGCC
ATGAATGTTCAGACGGTCTGAGGCAGTCTCAGAGGCTAGTATGGGGCTAGATGAAGCCCAGAGTAACACCCACAATATAAATGGGTTCCA
AAATGGCCCAAGTGAATCCTTGTCGCTGTGTTTTTTCTTTTAAACTTTCTGGTGTGAGAGGAGATGCCAAGGCATACAGTGAATAAAAGC

>65153_65153_16_PICALM-ME3_PICALM_chr11_85779693_ENST00000393346_ME3_chr11_86270865_ENST00000543262_length(amino acids)=576AA_BP=33
MPPSTVSPALPYPRQYARPRPTRSWGPRKSTWTGMAFTLEERLQLGIHGLIPPCFLSQDVQLLRIMRYYERQQSDLDKYIILMTLQDRNE
KLFYRVLTSDVEKFMPIVYTPTVGLACQHYGLTFRRPRGLFITIHDKGHLATMLNSWPEDNIKAVVVTDGERILGLGDLGCYGMGIPVGK
LALYTACGGVNPQQCLPVLLDVGTNNEELLRDPLYIGLKHQRVHGKAYDDLLDEFMQAVTDKFGINCLIQFEDFANANAFRLLNKYRNKY
CMFNDDIQGTASVAVAGILAALRITKNKLSNHVFVFQGAGEAAMGIAHLLVMALEKEGVPKAEATRKIWMVDSKGLIVKGRSHLNHEKEM
FAQDHPEVNSLEEVVRLVKPTAIIGVAAIAGAFTEQILRDMASFHERPIIFALSNPTSKAECTAEKCYRVTEGRGIFASGSPFKSVTLED
GKTFIPGQGNNAYVFPGVALGVIAGGIRHIPDEIFLLTAEQIAQEVSEQHLSQGRLYPPLSTIRDVSLRIAIKVLDYAYKHNLASYYPEP

--------------------------------------------------------------
>65153_65153_17_PICALM-ME3_PICALM_chr11_85779693_ENST00000526033_ME3_chr11_86270865_ENST00000323418_length(transcript)=1227nt_BP=447nt
GGAGCCTGGCGCCGCCATTTTCCTGCAGCTGCCTGTTCCTCTTACCCTGCCCGGCTCCAGCTGACCCGGGAAGGGGTGGGCTGAACTGAG
GCGGGGGCAAGGGAGTGCCCGACATCTTGTCCGACTCCGCGGGTGACACGAGCCGGTTCTCTCTGGACTGGTGGCAGCGCGCGGCCCCGA
ACCGCGCCCCAGGCCGGCAGGCGGGGAAGGAGCCGGTGGGGGTAGGGGGTGCGGTGGGGGGTGGGGACCCTCCGGCTCTTGGGGGTCCCA
GTCCCCGCCGGCTGCTGAGCGGGTGGGGTGGTGGAGGAGCTGCAGAGATGTCCGGCCAGAGCCTGACGGACCGAATCACTGCCGCCCAGC
ACAGTGTCACCGGCTCTGCCGTATCCAAGACAGTATGCAAGGCCACGACCCACGAGATCATGGGGCCCAAGAAAAAGCACCTGGACTATG
GCCTTTACCCTTGAAGAAAGGCTGCAGCTTGGAATCCACGGCCTAATCCCGCCCTGCTTTCTGAGCCAGGACGTCCAGCTCCTCCGAATC
ATGAGATATTACGAGCGGCAGCAGAGTGACCTGGACAAGTACATCATTCTCATGACACTCCAAGACCGGAACGAGAAGCTCTTCTACCGA
GTGCTGACTTCGGACGTGGAGAAGTTCATGCCAATCGTGTACACGCCTACCGTGGGGCTGGCCTGTCAGCACTATGGCCTGACTTTCCGC
AGGCCCCGTGGACTGTTCATCACCATTCATGACAAAGGTCATCTTGCAACAATGCTGAATTCTTGGCCAGAAGACAATATTAAGGCCGTG
GTGGTGACTGATGGGGAGCGCATCCTGGGCCTGGGAGACCTGGGCTGCTACGGCATGGGCATCCCTGTGGGCAAGCTGGCCCTGTACACG
GCATGCGGAGGGGTGAACCCGCAGCAGTGCCTCCCTGTGCTGCTGGACGTCGGCACCAACAATGAGGAGCTGCTCAGAGACCCTCTGTAC
ATCGGCCTGAAACACCAGCGCGTGCACGGGAAGGCATACGATGACTTGCTGGATGAGTTCATGCAGGCTGTGACAGACAAGTTTGGAATA
AATTGCCTCATCCAATTTGAAGACTTCGCCAATGCCAATGCCTTCCGCCTGCTCAACAAATACCGTAACAAGTACTGCATGTTCAATGAT

>65153_65153_17_PICALM-ME3_PICALM_chr11_85779693_ENST00000526033_ME3_chr11_86270865_ENST00000323418_length(amino acids)=292AA_BP=33
MPPSTVSPALPYPRQYARPRPTRSWGPRKSTWTMAFTLEERLQLGIHGLIPPCFLSQDVQLLRIMRYYERQQSDLDKYIILMTLQDRNEK
LFYRVLTSDVEKFMPIVYTPTVGLACQHYGLTFRRPRGLFITIHDKGHLATMLNSWPEDNIKAVVVTDGERILGLGDLGCYGMGIPVGKL
ALYTACGGVNPQQCLPVLLDVGTNNEELLRDPLYIGLKHQRVHGKAYDDLLDEFMQAVTDKFGINCLIQFEDFANANAFRLLNKYRNKYC

--------------------------------------------------------------
>65153_65153_18_PICALM-ME3_PICALM_chr11_85779693_ENST00000526033_ME3_chr11_86270865_ENST00000359636_length(transcript)=2250nt_BP=447nt
GGAGCCTGGCGCCGCCATTTTCCTGCAGCTGCCTGTTCCTCTTACCCTGCCCGGCTCCAGCTGACCCGGGAAGGGGTGGGCTGAACTGAG
GCGGGGGCAAGGGAGTGCCCGACATCTTGTCCGACTCCGCGGGTGACACGAGCCGGTTCTCTCTGGACTGGTGGCAGCGCGCGGCCCCGA
ACCGCGCCCCAGGCCGGCAGGCGGGGAAGGAGCCGGTGGGGGTAGGGGGTGCGGTGGGGGGTGGGGACCCTCCGGCTCTTGGGGGTCCCA
GTCCCCGCCGGCTGCTGAGCGGGTGGGGTGGTGGAGGAGCTGCAGAGATGTCCGGCCAGAGCCTGACGGACCGAATCACTGCCGCCCAGC
ACAGTGTCACCGGCTCTGCCGTATCCAAGACAGTATGCAAGGCCACGACCCACGAGATCATGGGGCCCAAGAAAAAGCACCTGGACTGGG
ATGGCCTTTACCCTTGAAGAAAGGCTGCAGCTTGGAATCCACGGCCTAATCCCGCCCTGCTTTCTGAGCCAGGACGTCCAGCTCCTCCGA
ATCATGAGATATTACGAGCGGCAGCAGAGTGACCTGGACAAGTACATCATTCTCATGACACTCCAAGACCGGAACGAGAAGCTCTTCTAC
CGAGTGCTGACTTCGGACGTGGAGAAGTTCATGCCAATCGTGTACACGCCTACCGTGGGGCTGGCCTGTCAGCACTATGGCCTGACTTTC
CGCAGGCCCCGTGGACTGTTCATCACCATTCATGACAAAGGTCATCTTGCAACAATGCTGAATTCTTGGCCAGAAGACAATATTAAGGCC
GTGGTGGTGACTGATGGGGAGCGCATCCTGGGCCTGGGAGACCTGGGCTGCTACGGCATGGGCATCCCTGTGGGCAAGCTGGCCCTGTAC
ACGGCATGCGGAGGGGTGAACCCGCAGCAGTGCCTCCCTGTGCTGCTGGACGTCGGCACCAACAATGAGGAGCTGCTCAGAGACCCTCTG
TACATCGGCCTGAAACACCAGCGCGTGCACGGGAAGGCATACGATGACTTGCTGGATGAGTTCATGCAGGCTGTGACAGACAAGTTTGGA
ATAAATTGCCTCATCCAATTTGAAGACTTCGCCAATGCCAATGCCTTCCGCCTGCTCAACAAATACCGTAACAAGTACTGCATGTTCAAT
GATGACATCCAAGGCACAGCCTCCGTTGCTGTGGCAGGGATCTTGGCTGCTCTGCGAATCACCAAGAACAAGCTTTCCAATCACGTGTTT
GTTTTCCAAGGTGCAGGCGAGGCAGCTATGGGCATTGCCCACCTCCTTGTCATGGCCCTAGAGAAAGAAGGTGTACCGAAGGCAGAGGCC
ACAAGAAAGATCTGGATGGTGGACTCTAAAGGGCTCATTGTCAAGGGGAGGAGCCACCTGAACCATGAAAAGGAGATGTTTGCCCAAGAC
CATCCTGAAGTCAACTCCCTGGAGGAGGTGGTGAGGCTGGTGAAGCCCACAGCCATCATAGGTGTTGCTGCCATCGCAGGAGCCTTCACG
GAGCAGATTCTGAGGGACATGGCCTCCTTCCACGAGCGCCCTATCATCTTTGCCCTGAGCAACCCCACCAGCAAGGCCGAGTGCACGGCT
GAGAAGTGCTACCGGGTCACCGAGGGCCGAGGGATTTTTGCCAGTGGAAGTCCTTTTAAGAGTGTGACTCTGGAAGATGGCAAGACCTTC
ATTCCTGGGCAGGGAAACAATGCTTACGTGTTCCCCGGGGTGGCACTGGGAGTCATCGCCGGCGGGATCCGGCACATCCCAGATGAGATC
TTCCTCCTGACAGCAGAGCAAATTGCCCAGGAAGTCTCTGAGCAGCATCTGTCCCAGGGGAGACTCTACCCACCACTCAGCACCATCCGA
GACGTGTCTTTGAGAATTGCCATCAAAGTTCTCGACTACGCGTACAAACACAACCTGGCTTCCTACTACCCAGAGCCTAAGGACAAGGAG
GCTTTTGTAAGATCCCTGGTCTACACTCCAGACTATGACTCCTTTACACTGGACAGCTACACTTGGCCCAAGGAAGCCATGAATGTTCAG
ACGGTCTGAGGCAGTCTCAGAGGCTAGTATGGGGCTAGATGAAGCCCAGAGTAACACCCACAATATAAATGGGTTCCAAAATGGCCCAAG
TGAATCCTTGTCGCTGTGTTTTTTCTTTTAAACTTTCTGGTGTGAGAGGAGATGCCAAGGCATACAGTGAATAAAAGCCTTGTCTCTGAA

>65153_65153_18_PICALM-ME3_PICALM_chr11_85779693_ENST00000526033_ME3_chr11_86270865_ENST00000359636_length(amino acids)=576AA_BP=33
MPPSTVSPALPYPRQYARPRPTRSWGPRKSTWTGMAFTLEERLQLGIHGLIPPCFLSQDVQLLRIMRYYERQQSDLDKYIILMTLQDRNE
KLFYRVLTSDVEKFMPIVYTPTVGLACQHYGLTFRRPRGLFITIHDKGHLATMLNSWPEDNIKAVVVTDGERILGLGDLGCYGMGIPVGK
LALYTACGGVNPQQCLPVLLDVGTNNEELLRDPLYIGLKHQRVHGKAYDDLLDEFMQAVTDKFGINCLIQFEDFANANAFRLLNKYRNKY
CMFNDDIQGTASVAVAGILAALRITKNKLSNHVFVFQGAGEAAMGIAHLLVMALEKEGVPKAEATRKIWMVDSKGLIVKGRSHLNHEKEM
FAQDHPEVNSLEEVVRLVKPTAIIGVAAIAGAFTEQILRDMASFHERPIIFALSNPTSKAECTAEKCYRVTEGRGIFASGSPFKSVTLED
GKTFIPGQGNNAYVFPGVALGVIAGGIRHIPDEIFLLTAEQIAQEVSEQHLSQGRLYPPLSTIRDVSLRIAIKVLDYAYKHNLASYYPEP

--------------------------------------------------------------
>65153_65153_19_PICALM-ME3_PICALM_chr11_85779693_ENST00000526033_ME3_chr11_86270865_ENST00000393324_length(transcript)=2250nt_BP=447nt
GGAGCCTGGCGCCGCCATTTTCCTGCAGCTGCCTGTTCCTCTTACCCTGCCCGGCTCCAGCTGACCCGGGAAGGGGTGGGCTGAACTGAG
GCGGGGGCAAGGGAGTGCCCGACATCTTGTCCGACTCCGCGGGTGACACGAGCCGGTTCTCTCTGGACTGGTGGCAGCGCGCGGCCCCGA
ACCGCGCCCCAGGCCGGCAGGCGGGGAAGGAGCCGGTGGGGGTAGGGGGTGCGGTGGGGGGTGGGGACCCTCCGGCTCTTGGGGGTCCCA
GTCCCCGCCGGCTGCTGAGCGGGTGGGGTGGTGGAGGAGCTGCAGAGATGTCCGGCCAGAGCCTGACGGACCGAATCACTGCCGCCCAGC
ACAGTGTCACCGGCTCTGCCGTATCCAAGACAGTATGCAAGGCCACGACCCACGAGATCATGGGGCCCAAGAAAAAGCACCTGGACTGGG
ATGGCCTTTACCCTTGAAGAAAGGCTGCAGCTTGGAATCCACGGCCTAATCCCGCCCTGCTTTCTGAGCCAGGACGTCCAGCTCCTCCGA
ATCATGAGATATTACGAGCGGCAGCAGAGTGACCTGGACAAGTACATCATTCTCATGACACTCCAAGACCGGAACGAGAAGCTCTTCTAC
CGAGTGCTGACTTCGGACGTGGAGAAGTTCATGCCAATCGTGTACACGCCTACCGTGGGGCTGGCCTGTCAGCACTATGGCCTGACTTTC
CGCAGGCCCCGTGGACTGTTCATCACCATTCATGACAAAGGTCATCTTGCAACAATGCTGAATTCTTGGCCAGAAGACAATATTAAGGCC
GTGGTGGTGACTGATGGGGAGCGCATCCTGGGCCTGGGAGACCTGGGCTGCTACGGCATGGGCATCCCTGTGGGCAAGCTGGCCCTGTAC
ACGGCATGCGGAGGGGTGAACCCGCAGCAGTGCCTCCCTGTGCTGCTGGACGTCGGCACCAACAATGAGGAGCTGCTCAGAGACCCTCTG
TACATCGGCCTGAAACACCAGCGCGTGCACGGGAAGGCATACGATGACTTGCTGGATGAGTTCATGCAGGCTGTGACAGACAAGTTTGGA
ATAAATTGCCTCATCCAATTTGAAGACTTCGCCAATGCCAATGCCTTCCGCCTGCTCAACAAATACCGTAACAAGTACTGCATGTTCAAT
GATGACATCCAAGGCACAGCCTCCGTTGCTGTGGCAGGGATCTTGGCTGCTCTGCGAATCACCAAGAACAAGCTTTCCAATCACGTGTTT
GTTTTCCAAGGTGCAGGCGAGGCAGCTATGGGCATTGCCCACCTCCTTGTCATGGCCCTAGAGAAAGAAGGTGTACCGAAGGCAGAGGCC
ACAAGAAAGATCTGGATGGTGGACTCTAAAGGGCTCATTGTCAAGGGGAGGAGCCACCTGAACCATGAAAAGGAGATGTTTGCCCAAGAC
CATCCTGAAGTCAACTCCCTGGAGGAGGTGGTGAGGCTGGTGAAGCCCACAGCCATCATAGGTGTTGCTGCCATCGCAGGAGCCTTCACG
GAGCAGATTCTGAGGGACATGGCCTCCTTCCACGAGCGCCCTATCATCTTTGCCCTGAGCAACCCCACCAGCAAGGCCGAGTGCACGGCT
GAGAAGTGCTACCGGGTCACCGAGGGCCGAGGGATTTTTGCCAGTGGAAGTCCTTTTAAGAGTGTGACTCTGGAAGATGGCAAGACCTTC
ATTCCTGGGCAGGGAAACAATGCTTACGTGTTCCCCGGGGTGGCACTGGGAGTCATCGCCGGCGGGATCCGGCACATCCCAGATGAGATC
TTCCTCCTGACAGCAGAGCAAATTGCCCAGGAAGTCTCTGAGCAGCATCTGTCCCAGGGGAGACTCTACCCACCACTCAGCACCATCCGA
GACGTGTCTTTGAGAATTGCCATCAAAGTTCTCGACTACGCGTACAAACACAACCTGGCTTCCTACTACCCAGAGCCTAAGGACAAGGAG
GCTTTTGTAAGATCCCTGGTCTACACTCCAGACTATGACTCCTTTACACTGGACAGCTACACTTGGCCCAAGGAAGCCATGAATGTTCAG
ACGGTCTGAGGCAGTCTCAGAGGCTAGTATGGGGCTAGATGAAGCCCAGAGTAACACCCACAATATAAATGGGTTCCAAAATGGCCCAAG
TGAATCCTTGTCGCTGTGTTTTTTCTTTTAAACTTTCTGGTGTGAGAGGAGATGCCAAGGCATACAGTGAATAAAAGCCTTGTCTCTGAA

>65153_65153_19_PICALM-ME3_PICALM_chr11_85779693_ENST00000526033_ME3_chr11_86270865_ENST00000393324_length(amino acids)=576AA_BP=33
MPPSTVSPALPYPRQYARPRPTRSWGPRKSTWTGMAFTLEERLQLGIHGLIPPCFLSQDVQLLRIMRYYERQQSDLDKYIILMTLQDRNE
KLFYRVLTSDVEKFMPIVYTPTVGLACQHYGLTFRRPRGLFITIHDKGHLATMLNSWPEDNIKAVVVTDGERILGLGDLGCYGMGIPVGK
LALYTACGGVNPQQCLPVLLDVGTNNEELLRDPLYIGLKHQRVHGKAYDDLLDEFMQAVTDKFGINCLIQFEDFANANAFRLLNKYRNKY
CMFNDDIQGTASVAVAGILAALRITKNKLSNHVFVFQGAGEAAMGIAHLLVMALEKEGVPKAEATRKIWMVDSKGLIVKGRSHLNHEKEM
FAQDHPEVNSLEEVVRLVKPTAIIGVAAIAGAFTEQILRDMASFHERPIIFALSNPTSKAECTAEKCYRVTEGRGIFASGSPFKSVTLED
GKTFIPGQGNNAYVFPGVALGVIAGGIRHIPDEIFLLTAEQIAQEVSEQHLSQGRLYPPLSTIRDVSLRIAIKVLDYAYKHNLASYYPEP

--------------------------------------------------------------
>65153_65153_20_PICALM-ME3_PICALM_chr11_85779693_ENST00000526033_ME3_chr11_86270865_ENST00000543262_length(transcript)=2248nt_BP=447nt
GGAGCCTGGCGCCGCCATTTTCCTGCAGCTGCCTGTTCCTCTTACCCTGCCCGGCTCCAGCTGACCCGGGAAGGGGTGGGCTGAACTGAG
GCGGGGGCAAGGGAGTGCCCGACATCTTGTCCGACTCCGCGGGTGACACGAGCCGGTTCTCTCTGGACTGGTGGCAGCGCGCGGCCCCGA
ACCGCGCCCCAGGCCGGCAGGCGGGGAAGGAGCCGGTGGGGGTAGGGGGTGCGGTGGGGGGTGGGGACCCTCCGGCTCTTGGGGGTCCCA
GTCCCCGCCGGCTGCTGAGCGGGTGGGGTGGTGGAGGAGCTGCAGAGATGTCCGGCCAGAGCCTGACGGACCGAATCACTGCCGCCCAGC
ACAGTGTCACCGGCTCTGCCGTATCCAAGACAGTATGCAAGGCCACGACCCACGAGATCATGGGGCCCAAGAAAAAGCACCTGGACTGGG
ATGGCCTTTACCCTTGAAGAAAGGCTGCAGCTTGGAATCCACGGCCTAATCCCGCCCTGCTTTCTGAGCCAGGACGTCCAGCTCCTCCGA
ATCATGAGATATTACGAGCGGCAGCAGAGTGACCTGGACAAGTACATCATTCTCATGACACTCCAAGACCGGAACGAGAAGCTCTTCTAC
CGAGTGCTGACTTCGGACGTGGAGAAGTTCATGCCAATCGTGTACACGCCTACCGTGGGGCTGGCCTGTCAGCACTATGGCCTGACTTTC
CGCAGGCCCCGTGGACTGTTCATCACCATTCATGACAAAGGTCATCTTGCAACAATGCTGAATTCTTGGCCAGAAGACAATATTAAGGCC
GTGGTGGTGACTGATGGGGAGCGCATCCTGGGCCTGGGAGACCTGGGCTGCTACGGCATGGGCATCCCTGTGGGCAAGCTGGCCCTGTAC
ACGGCATGCGGAGGGGTGAACCCGCAGCAGTGCCTCCCTGTGCTGCTGGACGTCGGCACCAACAATGAGGAGCTGCTCAGAGACCCTCTG
TACATCGGCCTGAAACACCAGCGCGTGCACGGGAAGGCATACGATGACTTGCTGGATGAGTTCATGCAGGCTGTGACAGACAAGTTTGGA
ATAAATTGCCTCATCCAATTTGAAGACTTCGCCAATGCCAATGCCTTCCGCCTGCTCAACAAATACCGTAACAAGTACTGCATGTTCAAT
GATGACATCCAAGGCACAGCCTCCGTTGCTGTGGCAGGGATCTTGGCTGCTCTGCGAATCACCAAGAACAAGCTTTCCAATCACGTGTTT
GTTTTCCAAGGTGCAGGCGAGGCAGCTATGGGCATTGCCCACCTCCTTGTCATGGCCCTAGAGAAAGAAGGTGTACCGAAGGCAGAGGCC
ACAAGAAAGATCTGGATGGTGGACTCTAAAGGGCTCATTGTCAAGGGGAGGAGCCACCTGAACCATGAAAAGGAGATGTTTGCCCAAGAC
CATCCTGAAGTCAACTCCCTGGAGGAGGTGGTGAGGCTGGTGAAGCCCACAGCCATCATAGGTGTTGCTGCCATCGCAGGAGCCTTCACG
GAGCAGATTCTGAGGGACATGGCCTCCTTCCACGAGCGCCCTATCATCTTTGCCCTGAGCAACCCCACCAGCAAGGCCGAGTGCACGGCT
GAGAAGTGCTACCGGGTCACCGAGGGCCGAGGGATTTTTGCCAGTGGAAGTCCTTTTAAGAGTGTGACTCTGGAAGATGGCAAGACCTTC
ATTCCTGGGCAGGGAAACAATGCTTACGTGTTCCCCGGGGTGGCACTGGGAGTCATCGCCGGCGGGATCCGGCACATCCCAGATGAGATC
TTCCTCCTGACAGCAGAGCAAATTGCCCAGGAAGTCTCTGAGCAGCATCTGTCCCAGGGGAGACTCTACCCACCACTCAGCACCATCCGA
GACGTGTCTTTGAGAATTGCCATCAAAGTTCTCGACTACGCGTACAAACACAACCTGGCTTCCTACTACCCAGAGCCTAAGGACAAGGAG
GCTTTTGTAAGATCCCTGGTCTACACTCCAGACTATGACTCCTTTACACTGGACAGCTACACTTGGCCCAAGGAAGCCATGAATGTTCAG
ACGGTCTGAGGCAGTCTCAGAGGCTAGTATGGGGCTAGATGAAGCCCAGAGTAACACCCACAATATAAATGGGTTCCAAAATGGCCCAAG

>65153_65153_20_PICALM-ME3_PICALM_chr11_85779693_ENST00000526033_ME3_chr11_86270865_ENST00000543262_length(amino acids)=576AA_BP=33
MPPSTVSPALPYPRQYARPRPTRSWGPRKSTWTGMAFTLEERLQLGIHGLIPPCFLSQDVQLLRIMRYYERQQSDLDKYIILMTLQDRNE
KLFYRVLTSDVEKFMPIVYTPTVGLACQHYGLTFRRPRGLFITIHDKGHLATMLNSWPEDNIKAVVVTDGERILGLGDLGCYGMGIPVGK
LALYTACGGVNPQQCLPVLLDVGTNNEELLRDPLYIGLKHQRVHGKAYDDLLDEFMQAVTDKFGINCLIQFEDFANANAFRLLNKYRNKY
CMFNDDIQGTASVAVAGILAALRITKNKLSNHVFVFQGAGEAAMGIAHLLVMALEKEGVPKAEATRKIWMVDSKGLIVKGRSHLNHEKEM
FAQDHPEVNSLEEVVRLVKPTAIIGVAAIAGAFTEQILRDMASFHERPIIFALSNPTSKAECTAEKCYRVTEGRGIFASGSPFKSVTLED
GKTFIPGQGNNAYVFPGVALGVIAGGIRHIPDEIFLLTAEQIAQEVSEQHLSQGRLYPPLSTIRDVSLRIAIKVLDYAYKHNLASYYPEP

--------------------------------------------------------------
>65153_65153_21_PICALM-ME3_PICALM_chr11_85779693_ENST00000532317_ME3_chr11_86270865_ENST00000323418_length(transcript)=1189nt_BP=409nt
CTCTTACCCTGCCCGGCTCCAGCTGACCCGGGAAGGGGTGGGCTGAACTGAGGCGGGGGCAAGGGAGTGCCCGACATCTTGTCCGACTCC
GCGGGTGACACGAGCCGGTTCTCTCTGGACTGGTGGCAGCGCGCGGCCCCGAACCGCGCCCCAGGCCGGCAGGCGGGGAAGGAGCCGGTG
GGGGTAGGGGGTGCGGTGGGGGGTGGGGACCCTCCGGCTCTTGGGGGTCCCAGTCCCCGCCGGCTGCTGAGCGGGTGGGGTGGTGGAGGA
GCTGCAGAGATGTCCGGCCAGAGCCTGACGGACCGAATCACTGCCGCCCAGCACAGTGTCACCGGCTCTGCCGTATCCAAGACAGTATGC
AAGGCCACGACCCACGAGATCATGGGGCCCAAGAAAAAGCACCTGGACTATGGCCTTTACCCTTGAAGAAAGGCTGCAGCTTGGAATCCA
CGGCCTAATCCCGCCCTGCTTTCTGAGCCAGGACGTCCAGCTCCTCCGAATCATGAGATATTACGAGCGGCAGCAGAGTGACCTGGACAA
GTACATCATTCTCATGACACTCCAAGACCGGAACGAGAAGCTCTTCTACCGAGTGCTGACTTCGGACGTGGAGAAGTTCATGCCAATCGT
GTACACGCCTACCGTGGGGCTGGCCTGTCAGCACTATGGCCTGACTTTCCGCAGGCCCCGTGGACTGTTCATCACCATTCATGACAAAGG
TCATCTTGCAACAATGCTGAATTCTTGGCCAGAAGACAATATTAAGGCCGTGGTGGTGACTGATGGGGAGCGCATCCTGGGCCTGGGAGA
CCTGGGCTGCTACGGCATGGGCATCCCTGTGGGCAAGCTGGCCCTGTACACGGCATGCGGAGGGGTGAACCCGCAGCAGTGCCTCCCTGT
GCTGCTGGACGTCGGCACCAACAATGAGGAGCTGCTCAGAGACCCTCTGTACATCGGCCTGAAACACCAGCGCGTGCACGGGAAGGCATA
CGATGACTTGCTGGATGAGTTCATGCAGGCTGTGACAGACAAGTTTGGAATAAATTGCCTCATCCAATTTGAAGACTTCGCCAATGCCAA
TGCCTTCCGCCTGCTCAACAAATACCGTAACAAGTACTGCATGTTCAATGATGACATCCAAGATGACTTCTCCAGAGGCCCAAAGAGGTC

>65153_65153_21_PICALM-ME3_PICALM_chr11_85779693_ENST00000532317_ME3_chr11_86270865_ENST00000323418_length(amino acids)=293AA_BP=33
MPPSTVSPALPYPRQYARPRPTRSWGPRKSTWTMAFTLEERLQLGIHGLIPPCFLSQDVQLLRIMRYYERQQSDLDKYIILMTLQDRNEK
LFYRVLTSDVEKFMPIVYTPTVGLACQHYGLTFRRPRGLFITIHDKGHLATMLNSWPEDNIKAVVVTDGERILGLGDLGCYGMGIPVGKL
ALYTACGGVNPQQCLPVLLDVGTNNEELLRDPLYIGLKHQRVHGKAYDDLLDEFMQAVTDKFGINCLIQFEDFANANAFRLLNKYRNKYC

--------------------------------------------------------------
>65153_65153_22_PICALM-ME3_PICALM_chr11_85779693_ENST00000532317_ME3_chr11_86270865_ENST00000359636_length(transcript)=2212nt_BP=409nt
CTCTTACCCTGCCCGGCTCCAGCTGACCCGGGAAGGGGTGGGCTGAACTGAGGCGGGGGCAAGGGAGTGCCCGACATCTTGTCCGACTCC
GCGGGTGACACGAGCCGGTTCTCTCTGGACTGGTGGCAGCGCGCGGCCCCGAACCGCGCCCCAGGCCGGCAGGCGGGGAAGGAGCCGGTG
GGGGTAGGGGGTGCGGTGGGGGGTGGGGACCCTCCGGCTCTTGGGGGTCCCAGTCCCCGCCGGCTGCTGAGCGGGTGGGGTGGTGGAGGA
GCTGCAGAGATGTCCGGCCAGAGCCTGACGGACCGAATCACTGCCGCCCAGCACAGTGTCACCGGCTCTGCCGTATCCAAGACAGTATGC
AAGGCCACGACCCACGAGATCATGGGGCCCAAGAAAAAGCACCTGGACTGGGATGGCCTTTACCCTTGAAGAAAGGCTGCAGCTTGGAAT
CCACGGCCTAATCCCGCCCTGCTTTCTGAGCCAGGACGTCCAGCTCCTCCGAATCATGAGATATTACGAGCGGCAGCAGAGTGACCTGGA
CAAGTACATCATTCTCATGACACTCCAAGACCGGAACGAGAAGCTCTTCTACCGAGTGCTGACTTCGGACGTGGAGAAGTTCATGCCAAT
CGTGTACACGCCTACCGTGGGGCTGGCCTGTCAGCACTATGGCCTGACTTTCCGCAGGCCCCGTGGACTGTTCATCACCATTCATGACAA
AGGTCATCTTGCAACAATGCTGAATTCTTGGCCAGAAGACAATATTAAGGCCGTGGTGGTGACTGATGGGGAGCGCATCCTGGGCCTGGG
AGACCTGGGCTGCTACGGCATGGGCATCCCTGTGGGCAAGCTGGCCCTGTACACGGCATGCGGAGGGGTGAACCCGCAGCAGTGCCTCCC
TGTGCTGCTGGACGTCGGCACCAACAATGAGGAGCTGCTCAGAGACCCTCTGTACATCGGCCTGAAACACCAGCGCGTGCACGGGAAGGC
ATACGATGACTTGCTGGATGAGTTCATGCAGGCTGTGACAGACAAGTTTGGAATAAATTGCCTCATCCAATTTGAAGACTTCGCCAATGC
CAATGCCTTCCGCCTGCTCAACAAATACCGTAACAAGTACTGCATGTTCAATGATGACATCCAAGGCACAGCCTCCGTTGCTGTGGCAGG
GATCTTGGCTGCTCTGCGAATCACCAAGAACAAGCTTTCCAATCACGTGTTTGTTTTCCAAGGTGCAGGCGAGGCAGCTATGGGCATTGC
CCACCTCCTTGTCATGGCCCTAGAGAAAGAAGGTGTACCGAAGGCAGAGGCCACAAGAAAGATCTGGATGGTGGACTCTAAAGGGCTCAT
TGTCAAGGGGAGGAGCCACCTGAACCATGAAAAGGAGATGTTTGCCCAAGACCATCCTGAAGTCAACTCCCTGGAGGAGGTGGTGAGGCT
GGTGAAGCCCACAGCCATCATAGGTGTTGCTGCCATCGCAGGAGCCTTCACGGAGCAGATTCTGAGGGACATGGCCTCCTTCCACGAGCG
CCCTATCATCTTTGCCCTGAGCAACCCCACCAGCAAGGCCGAGTGCACGGCTGAGAAGTGCTACCGGGTCACCGAGGGCCGAGGGATTTT
TGCCAGTGGAAGTCCTTTTAAGAGTGTGACTCTGGAAGATGGCAAGACCTTCATTCCTGGGCAGGGAAACAATGCTTACGTGTTCCCCGG
GGTGGCACTGGGAGTCATCGCCGGCGGGATCCGGCACATCCCAGATGAGATCTTCCTCCTGACAGCAGAGCAAATTGCCCAGGAAGTCTC
TGAGCAGCATCTGTCCCAGGGGAGACTCTACCCACCACTCAGCACCATCCGAGACGTGTCTTTGAGAATTGCCATCAAAGTTCTCGACTA
CGCGTACAAACACAACCTGGCTTCCTACTACCCAGAGCCTAAGGACAAGGAGGCTTTTGTAAGATCCCTGGTCTACACTCCAGACTATGA
CTCCTTTACACTGGACAGCTACACTTGGCCCAAGGAAGCCATGAATGTTCAGACGGTCTGAGGCAGTCTCAGAGGCTAGTATGGGGCTAG
ATGAAGCCCAGAGTAACACCCACAATATAAATGGGTTCCAAAATGGCCCAAGTGAATCCTTGTCGCTGTGTTTTTTCTTTTAAACTTTCT

>65153_65153_22_PICALM-ME3_PICALM_chr11_85779693_ENST00000532317_ME3_chr11_86270865_ENST00000359636_length(amino acids)=576AA_BP=33
MPPSTVSPALPYPRQYARPRPTRSWGPRKSTWTGMAFTLEERLQLGIHGLIPPCFLSQDVQLLRIMRYYERQQSDLDKYIILMTLQDRNE
KLFYRVLTSDVEKFMPIVYTPTVGLACQHYGLTFRRPRGLFITIHDKGHLATMLNSWPEDNIKAVVVTDGERILGLGDLGCYGMGIPVGK
LALYTACGGVNPQQCLPVLLDVGTNNEELLRDPLYIGLKHQRVHGKAYDDLLDEFMQAVTDKFGINCLIQFEDFANANAFRLLNKYRNKY
CMFNDDIQGTASVAVAGILAALRITKNKLSNHVFVFQGAGEAAMGIAHLLVMALEKEGVPKAEATRKIWMVDSKGLIVKGRSHLNHEKEM
FAQDHPEVNSLEEVVRLVKPTAIIGVAAIAGAFTEQILRDMASFHERPIIFALSNPTSKAECTAEKCYRVTEGRGIFASGSPFKSVTLED
GKTFIPGQGNNAYVFPGVALGVIAGGIRHIPDEIFLLTAEQIAQEVSEQHLSQGRLYPPLSTIRDVSLRIAIKVLDYAYKHNLASYYPEP

--------------------------------------------------------------
>65153_65153_23_PICALM-ME3_PICALM_chr11_85779693_ENST00000532317_ME3_chr11_86270865_ENST00000393324_length(transcript)=2212nt_BP=409nt
CTCTTACCCTGCCCGGCTCCAGCTGACCCGGGAAGGGGTGGGCTGAACTGAGGCGGGGGCAAGGGAGTGCCCGACATCTTGTCCGACTCC
GCGGGTGACACGAGCCGGTTCTCTCTGGACTGGTGGCAGCGCGCGGCCCCGAACCGCGCCCCAGGCCGGCAGGCGGGGAAGGAGCCGGTG
GGGGTAGGGGGTGCGGTGGGGGGTGGGGACCCTCCGGCTCTTGGGGGTCCCAGTCCCCGCCGGCTGCTGAGCGGGTGGGGTGGTGGAGGA
GCTGCAGAGATGTCCGGCCAGAGCCTGACGGACCGAATCACTGCCGCCCAGCACAGTGTCACCGGCTCTGCCGTATCCAAGACAGTATGC
AAGGCCACGACCCACGAGATCATGGGGCCCAAGAAAAAGCACCTGGACTGGGATGGCCTTTACCCTTGAAGAAAGGCTGCAGCTTGGAAT
CCACGGCCTAATCCCGCCCTGCTTTCTGAGCCAGGACGTCCAGCTCCTCCGAATCATGAGATATTACGAGCGGCAGCAGAGTGACCTGGA
CAAGTACATCATTCTCATGACACTCCAAGACCGGAACGAGAAGCTCTTCTACCGAGTGCTGACTTCGGACGTGGAGAAGTTCATGCCAAT
CGTGTACACGCCTACCGTGGGGCTGGCCTGTCAGCACTATGGCCTGACTTTCCGCAGGCCCCGTGGACTGTTCATCACCATTCATGACAA
AGGTCATCTTGCAACAATGCTGAATTCTTGGCCAGAAGACAATATTAAGGCCGTGGTGGTGACTGATGGGGAGCGCATCCTGGGCCTGGG
AGACCTGGGCTGCTACGGCATGGGCATCCCTGTGGGCAAGCTGGCCCTGTACACGGCATGCGGAGGGGTGAACCCGCAGCAGTGCCTCCC
TGTGCTGCTGGACGTCGGCACCAACAATGAGGAGCTGCTCAGAGACCCTCTGTACATCGGCCTGAAACACCAGCGCGTGCACGGGAAGGC
ATACGATGACTTGCTGGATGAGTTCATGCAGGCTGTGACAGACAAGTTTGGAATAAATTGCCTCATCCAATTTGAAGACTTCGCCAATGC
CAATGCCTTCCGCCTGCTCAACAAATACCGTAACAAGTACTGCATGTTCAATGATGACATCCAAGGCACAGCCTCCGTTGCTGTGGCAGG
GATCTTGGCTGCTCTGCGAATCACCAAGAACAAGCTTTCCAATCACGTGTTTGTTTTCCAAGGTGCAGGCGAGGCAGCTATGGGCATTGC
CCACCTCCTTGTCATGGCCCTAGAGAAAGAAGGTGTACCGAAGGCAGAGGCCACAAGAAAGATCTGGATGGTGGACTCTAAAGGGCTCAT
TGTCAAGGGGAGGAGCCACCTGAACCATGAAAAGGAGATGTTTGCCCAAGACCATCCTGAAGTCAACTCCCTGGAGGAGGTGGTGAGGCT
GGTGAAGCCCACAGCCATCATAGGTGTTGCTGCCATCGCAGGAGCCTTCACGGAGCAGATTCTGAGGGACATGGCCTCCTTCCACGAGCG
CCCTATCATCTTTGCCCTGAGCAACCCCACCAGCAAGGCCGAGTGCACGGCTGAGAAGTGCTACCGGGTCACCGAGGGCCGAGGGATTTT
TGCCAGTGGAAGTCCTTTTAAGAGTGTGACTCTGGAAGATGGCAAGACCTTCATTCCTGGGCAGGGAAACAATGCTTACGTGTTCCCCGG
GGTGGCACTGGGAGTCATCGCCGGCGGGATCCGGCACATCCCAGATGAGATCTTCCTCCTGACAGCAGAGCAAATTGCCCAGGAAGTCTC
TGAGCAGCATCTGTCCCAGGGGAGACTCTACCCACCACTCAGCACCATCCGAGACGTGTCTTTGAGAATTGCCATCAAAGTTCTCGACTA
CGCGTACAAACACAACCTGGCTTCCTACTACCCAGAGCCTAAGGACAAGGAGGCTTTTGTAAGATCCCTGGTCTACACTCCAGACTATGA
CTCCTTTACACTGGACAGCTACACTTGGCCCAAGGAAGCCATGAATGTTCAGACGGTCTGAGGCAGTCTCAGAGGCTAGTATGGGGCTAG
ATGAAGCCCAGAGTAACACCCACAATATAAATGGGTTCCAAAATGGCCCAAGTGAATCCTTGTCGCTGTGTTTTTTCTTTTAAACTTTCT

>65153_65153_23_PICALM-ME3_PICALM_chr11_85779693_ENST00000532317_ME3_chr11_86270865_ENST00000393324_length(amino acids)=576AA_BP=33
MPPSTVSPALPYPRQYARPRPTRSWGPRKSTWTGMAFTLEERLQLGIHGLIPPCFLSQDVQLLRIMRYYERQQSDLDKYIILMTLQDRNE
KLFYRVLTSDVEKFMPIVYTPTVGLACQHYGLTFRRPRGLFITIHDKGHLATMLNSWPEDNIKAVVVTDGERILGLGDLGCYGMGIPVGK
LALYTACGGVNPQQCLPVLLDVGTNNEELLRDPLYIGLKHQRVHGKAYDDLLDEFMQAVTDKFGINCLIQFEDFANANAFRLLNKYRNKY
CMFNDDIQGTASVAVAGILAALRITKNKLSNHVFVFQGAGEAAMGIAHLLVMALEKEGVPKAEATRKIWMVDSKGLIVKGRSHLNHEKEM
FAQDHPEVNSLEEVVRLVKPTAIIGVAAIAGAFTEQILRDMASFHERPIIFALSNPTSKAECTAEKCYRVTEGRGIFASGSPFKSVTLED
GKTFIPGQGNNAYVFPGVALGVIAGGIRHIPDEIFLLTAEQIAQEVSEQHLSQGRLYPPLSTIRDVSLRIAIKVLDYAYKHNLASYYPEP

--------------------------------------------------------------
>65153_65153_24_PICALM-ME3_PICALM_chr11_85779693_ENST00000532317_ME3_chr11_86270865_ENST00000543262_length(transcript)=2210nt_BP=409nt
CTCTTACCCTGCCCGGCTCCAGCTGACCCGGGAAGGGGTGGGCTGAACTGAGGCGGGGGCAAGGGAGTGCCCGACATCTTGTCCGACTCC
GCGGGTGACACGAGCCGGTTCTCTCTGGACTGGTGGCAGCGCGCGGCCCCGAACCGCGCCCCAGGCCGGCAGGCGGGGAAGGAGCCGGTG
GGGGTAGGGGGTGCGGTGGGGGGTGGGGACCCTCCGGCTCTTGGGGGTCCCAGTCCCCGCCGGCTGCTGAGCGGGTGGGGTGGTGGAGGA
GCTGCAGAGATGTCCGGCCAGAGCCTGACGGACCGAATCACTGCCGCCCAGCACAGTGTCACCGGCTCTGCCGTATCCAAGACAGTATGC
AAGGCCACGACCCACGAGATCATGGGGCCCAAGAAAAAGCACCTGGACTGGGATGGCCTTTACCCTTGAAGAAAGGCTGCAGCTTGGAAT
CCACGGCCTAATCCCGCCCTGCTTTCTGAGCCAGGACGTCCAGCTCCTCCGAATCATGAGATATTACGAGCGGCAGCAGAGTGACCTGGA
CAAGTACATCATTCTCATGACACTCCAAGACCGGAACGAGAAGCTCTTCTACCGAGTGCTGACTTCGGACGTGGAGAAGTTCATGCCAAT
CGTGTACACGCCTACCGTGGGGCTGGCCTGTCAGCACTATGGCCTGACTTTCCGCAGGCCCCGTGGACTGTTCATCACCATTCATGACAA
AGGTCATCTTGCAACAATGCTGAATTCTTGGCCAGAAGACAATATTAAGGCCGTGGTGGTGACTGATGGGGAGCGCATCCTGGGCCTGGG
AGACCTGGGCTGCTACGGCATGGGCATCCCTGTGGGCAAGCTGGCCCTGTACACGGCATGCGGAGGGGTGAACCCGCAGCAGTGCCTCCC
TGTGCTGCTGGACGTCGGCACCAACAATGAGGAGCTGCTCAGAGACCCTCTGTACATCGGCCTGAAACACCAGCGCGTGCACGGGAAGGC
ATACGATGACTTGCTGGATGAGTTCATGCAGGCTGTGACAGACAAGTTTGGAATAAATTGCCTCATCCAATTTGAAGACTTCGCCAATGC
CAATGCCTTCCGCCTGCTCAACAAATACCGTAACAAGTACTGCATGTTCAATGATGACATCCAAGGCACAGCCTCCGTTGCTGTGGCAGG
GATCTTGGCTGCTCTGCGAATCACCAAGAACAAGCTTTCCAATCACGTGTTTGTTTTCCAAGGTGCAGGCGAGGCAGCTATGGGCATTGC
CCACCTCCTTGTCATGGCCCTAGAGAAAGAAGGTGTACCGAAGGCAGAGGCCACAAGAAAGATCTGGATGGTGGACTCTAAAGGGCTCAT
TGTCAAGGGGAGGAGCCACCTGAACCATGAAAAGGAGATGTTTGCCCAAGACCATCCTGAAGTCAACTCCCTGGAGGAGGTGGTGAGGCT
GGTGAAGCCCACAGCCATCATAGGTGTTGCTGCCATCGCAGGAGCCTTCACGGAGCAGATTCTGAGGGACATGGCCTCCTTCCACGAGCG
CCCTATCATCTTTGCCCTGAGCAACCCCACCAGCAAGGCCGAGTGCACGGCTGAGAAGTGCTACCGGGTCACCGAGGGCCGAGGGATTTT
TGCCAGTGGAAGTCCTTTTAAGAGTGTGACTCTGGAAGATGGCAAGACCTTCATTCCTGGGCAGGGAAACAATGCTTACGTGTTCCCCGG
GGTGGCACTGGGAGTCATCGCCGGCGGGATCCGGCACATCCCAGATGAGATCTTCCTCCTGACAGCAGAGCAAATTGCCCAGGAAGTCTC
TGAGCAGCATCTGTCCCAGGGGAGACTCTACCCACCACTCAGCACCATCCGAGACGTGTCTTTGAGAATTGCCATCAAAGTTCTCGACTA
CGCGTACAAACACAACCTGGCTTCCTACTACCCAGAGCCTAAGGACAAGGAGGCTTTTGTAAGATCCCTGGTCTACACTCCAGACTATGA
CTCCTTTACACTGGACAGCTACACTTGGCCCAAGGAAGCCATGAATGTTCAGACGGTCTGAGGCAGTCTCAGAGGCTAGTATGGGGCTAG
ATGAAGCCCAGAGTAACACCCACAATATAAATGGGTTCCAAAATGGCCCAAGTGAATCCTTGTCGCTGTGTTTTTTCTTTTAAACTTTCT

>65153_65153_24_PICALM-ME3_PICALM_chr11_85779693_ENST00000532317_ME3_chr11_86270865_ENST00000543262_length(amino acids)=576AA_BP=33
MPPSTVSPALPYPRQYARPRPTRSWGPRKSTWTGMAFTLEERLQLGIHGLIPPCFLSQDVQLLRIMRYYERQQSDLDKYIILMTLQDRNE
KLFYRVLTSDVEKFMPIVYTPTVGLACQHYGLTFRRPRGLFITIHDKGHLATMLNSWPEDNIKAVVVTDGERILGLGDLGCYGMGIPVGK
LALYTACGGVNPQQCLPVLLDVGTNNEELLRDPLYIGLKHQRVHGKAYDDLLDEFMQAVTDKFGINCLIQFEDFANANAFRLLNKYRNKY
CMFNDDIQGTASVAVAGILAALRITKNKLSNHVFVFQGAGEAAMGIAHLLVMALEKEGVPKAEATRKIWMVDSKGLIVKGRSHLNHEKEM
FAQDHPEVNSLEEVVRLVKPTAIIGVAAIAGAFTEQILRDMASFHERPIIFALSNPTSKAECTAEKCYRVTEGRGIFASGSPFKSVTLED
GKTFIPGQGNNAYVFPGVALGVIAGGIRHIPDEIFLLTAEQIAQEVSEQHLSQGRLYPPLSTIRDVSLRIAIKVLDYAYKHNLASYYPEP

--------------------------------------------------------------

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Fusion Gene PPI Analysis for PICALM-ME3


check button Go to ChiPPI (Chimeric Protein-Protein interactions) to see the chimeric PPI interaction in

ChiPPI page.


check button Protein-protein interactors with each fusion partner protein in wild-type (BIOGRID-3.4.160)
HgeneHgene's interactorsTgeneTgene's interactors


check button - Retained PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenStill interaction with
HgenePICALMchr11:85707868chr11:86176242ENST00000356360-1219221_294419.3333333333333633.0PIMREG
HgenePICALMchr11:85707868chr11:86176242ENST00000393346-1220221_294419.3333333333333653.0PIMREG
HgenePICALMchr11:85707868chr11:86176242ENST00000526033-1220221_294419.3333333333333646.0PIMREG
HgenePICALMchr11:85707868chr11:86176242ENST00000528398-1219221_294368.3333333333333552.0PIMREG
HgenePICALMchr11:85707868chr11:86176242ENST00000532317-1220221_294419.3333333333333611.0PIMREG
HgenePICALMchr11:85707869chr11:86176242ENST00000356360-1219221_294419.3333333333333633.0PIMREG
HgenePICALMchr11:85707869chr11:86176242ENST00000393346-1220221_294419.3333333333333653.0PIMREG
HgenePICALMchr11:85707869chr11:86176242ENST00000526033-1220221_294419.3333333333333646.0PIMREG
HgenePICALMchr11:85707869chr11:86176242ENST00000528398-1219221_294368.3333333333333552.0PIMREG
HgenePICALMchr11:85707869chr11:86176242ENST00000532317-1220221_294419.3333333333333611.0PIMREG


check button - Lost PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with
HgenePICALMchr11:85779693chr11:86270865ENST00000356360-119221_29443.333333333333336633.0PIMREG
HgenePICALMchr11:85779693chr11:86270865ENST00000393346-120221_29443.333333333333336653.0PIMREG
HgenePICALMchr11:85779693chr11:86270865ENST00000526033-120221_29443.333333333333336646.0PIMREG
HgenePICALMchr11:85779693chr11:86270865ENST00000528398-119221_2940552.0PIMREG
HgenePICALMchr11:85779693chr11:86270865ENST00000532317-120221_29443.333333333333336611.0PIMREG


check button - Retained PPIs, but lost function due to frame-shift fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


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Related Drugs for PICALM-ME3


check button Drugs targeting genes involved in this fusion gene.
(DrugBank Version 5.1.8 2021-05-08)
PartnerGeneUniProtAccDrugBank IDDrug nameDrug activityDrug typeDrug status

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Related Diseases for PICALM-ME3


check button Diseases associated with fusion partners.
(DisGeNet 4.0)
PartnerGeneDisease IDDisease name# pubmedsSource