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Center for Computational Systems Medicine
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Fusion Gene Summary

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Fusion Gene ORF analysis

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Fusion Genomic Features

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Fusion Protein Features

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Fusion Gene Sequence

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Fusion Gene PPI analysis

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Related Drugs

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Related Diseases

Fusion gene:PIP5K1B-PGM5 (FusionGDB2 ID:65519)

Fusion Gene Summary for PIP5K1B-PGM5

check button Fusion gene summary
Fusion gene informationFusion gene name: PIP5K1B-PGM5
Fusion gene ID: 65519
HgeneTgene
Gene symbol

PIP5K1B

PGM5

Gene ID

8395

5239

Gene namephosphatidylinositol-4-phosphate 5-kinase type 1 betaphosphoglucomutase 5
SynonymsMSS4|STM7PGMRP
Cytomap

9q21.11

9q21.11

Type of geneprotein-codingprotein-coding
Descriptionphosphatidylinositol 4-phosphate 5-kinase type-1 betaPIP5K1-betaPIP5KIbetaphosphatidylinositol 4-phosphate 5-kinase type I betaprotein STM-7ptdIns(4)P-5-kinase 1 betatype I phosphatidylinositol 4-phosphate 5-kinase betaphosphoglucomutase-like protein 5PGM-RPaciculinphosphoglucomutase-related protein
Modification date2020031320200313
UniProtAcc..
Ensembl transtripts involved in fusion geneENST00000265382, ENST00000541509, 
ENST00000474356, 		ENST00000396392, 
ENST00000396396, ENST00000604870, 
Fusion gene scores* DoF score9 X 8 X 8=5763 X 5 X 4=60
# samples 147
** MAII scorelog2(14/576*10)=-2.04064198449735
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0		log2(7/60*10)=0.222392421336448
effective Gene in Pan-Cancer Fusion Genes (eGinPCFGs).
DoF>8 and MAII>0
Context

PubMed: PIP5K1B [Title/Abstract] AND PGM5 [Title/Abstract] AND fusion [Title/Abstract]

Most frequent breakpointPIP5K1B(71491710)-PGM5(71094334), # samples:3
PIP5K1B(71437599)-PGM5(71080009), # samples:3
Anticipated loss of major functional domain due to fusion event.PIP5K1B-PGM5 seems lost the major protein functional domain in Hgene partner, which is a cell metabolism gene due to the frame-shifted ORF.
PIP5K1B-PGM5 seems lost the major protein functional domain in Hgene partner, which is a IUPHAR drug target due to the frame-shifted ORF.
PIP5K1B-PGM5 seems lost the major protein functional domain in Tgene partner, which is a essential gene due to the frame-shifted ORF.
* DoF score (Degree of Frequency) = # partners X # break points X # cancer types
** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10)

check button Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez
PartnerGeneGO IDGO termPubMed ID

check buttonFusion gene breakpoints across PIP5K1B (5'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.
all structure

check buttonFusion gene breakpoints across PGM5 (3'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.
all structure

check button Fusion gene information from two resources (ChiTars 5.0 and ChimerDB 4.0)
* All genome coordinats were lifted-over on hg19.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
SourceDiseaseSampleHgeneHchrHbpHstrandTgeneTchrTbpTstrand
ChimerDB4BRCATCGA-AN-A0AL-01APIP5K1Bchr9

71555706

-PGM5chr9

71080009

+
ChimerDB4BRCATCGA-AN-A0AL-01APIP5K1Bchr9

71555706

+PGM5chr9

71080009

+
ChimerDB4ESCATCGA-L5-A891-01APIP5K1Bchr9

71491710

-PGM5chr9

71094334

+
ChimerDB4ESCATCGA-L5-A891-01APIP5K1Bchr9

71491710

+PGM5chr9

71094334

+
ChimerDB4ESCATCGA-L5-A891PIP5K1Bchr9

71491710

+PGM5chr9

71094333

+
ChimerDB4ESCATCGA-L5-A891PIP5K1Bchr9

71491710

+PGM5chr9

71094334

+
ChimerDB4UCECTCGA-A5-A7WK-01APIP5K1Bchr9

71437599

-PGM5chr9

71080009

+
ChimerDB4UCECTCGA-A5-A7WK-01APIP5K1Bchr9

71437599

+PGM5chr9

71080009

+
ChimerDB4UCECTCGA-A5-A7WKPIP5K1Bchr9

71437599

+PGM5chr9

71080008

+
ChimerDB4UCECTCGA-A5-A7WKPIP5K1Bchr9

71437599

+PGM5chr9

71080009

+


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Fusion Gene ORF analysis for PIP5K1B-PGM5

check button Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
ORFHenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrand
5CDS-intronENST00000265382ENST00000396392PIP5K1Bchr9

71491710

+PGM5chr9

71094334

+
5CDS-intronENST00000265382ENST00000396392PIP5K1Bchr9

71491710

+PGM5chr9

71094333

+
5CDS-intronENST00000265382ENST00000396396PIP5K1Bchr9

71491710

+PGM5chr9

71094334

+
5CDS-intronENST00000265382ENST00000396396PIP5K1Bchr9

71491710

+PGM5chr9

71094333

+
5CDS-intronENST00000265382ENST00000604870PIP5K1Bchr9

71555706

+PGM5chr9

71080009

+
5CDS-intronENST00000265382ENST00000604870PIP5K1Bchr9

71491710

+PGM5chr9

71094334

+
5CDS-intronENST00000265382ENST00000604870PIP5K1Bchr9

71491710

+PGM5chr9

71094333

+
5CDS-intronENST00000265382ENST00000604870PIP5K1Bchr9

71437599

+PGM5chr9

71080009

+
5CDS-intronENST00000265382ENST00000604870PIP5K1Bchr9

71437599

+PGM5chr9

71080008

+
5CDS-intronENST00000541509ENST00000396392PIP5K1Bchr9

71491710

+PGM5chr9

71094334

+
5CDS-intronENST00000541509ENST00000396392PIP5K1Bchr9

71491710

+PGM5chr9

71094333

+
5CDS-intronENST00000541509ENST00000396396PIP5K1Bchr9

71491710

+PGM5chr9

71094334

+
5CDS-intronENST00000541509ENST00000396396PIP5K1Bchr9

71491710

+PGM5chr9

71094333

+
5CDS-intronENST00000541509ENST00000604870PIP5K1Bchr9

71555706

+PGM5chr9

71080009

+
5CDS-intronENST00000541509ENST00000604870PIP5K1Bchr9

71491710

+PGM5chr9

71094334

+
5CDS-intronENST00000541509ENST00000604870PIP5K1Bchr9

71491710

+PGM5chr9

71094333

+
5CDS-intronENST00000541509ENST00000604870PIP5K1Bchr9

71437599

+PGM5chr9

71080009

+
5CDS-intronENST00000541509ENST00000604870PIP5K1Bchr9

71437599

+PGM5chr9

71080008

+
Frame-shiftENST00000265382ENST00000396392PIP5K1Bchr9

71437599

+PGM5chr9

71080009

+
Frame-shiftENST00000265382ENST00000396392PIP5K1Bchr9

71437599

+PGM5chr9

71080008

+
Frame-shiftENST00000265382ENST00000396396PIP5K1Bchr9

71437599

+PGM5chr9

71080009

+
Frame-shiftENST00000265382ENST00000396396PIP5K1Bchr9

71437599

+PGM5chr9

71080008

+
Frame-shiftENST00000541509ENST00000396392PIP5K1Bchr9

71437599

+PGM5chr9

71080009

+
Frame-shiftENST00000541509ENST00000396392PIP5K1Bchr9

71437599

+PGM5chr9

71080008

+
Frame-shiftENST00000541509ENST00000396396PIP5K1Bchr9

71437599

+PGM5chr9

71080009

+
Frame-shiftENST00000541509ENST00000396396PIP5K1Bchr9

71437599

+PGM5chr9

71080008

+
In-frameENST00000265382ENST00000396392PIP5K1Bchr9

71555706

+PGM5chr9

71080009

+
In-frameENST00000265382ENST00000396396PIP5K1Bchr9

71555706

+PGM5chr9

71080009

+
In-frameENST00000541509ENST00000396392PIP5K1Bchr9

71555706

+PGM5chr9

71080009

+
In-frameENST00000541509ENST00000396396PIP5K1Bchr9

71555706

+PGM5chr9

71080009

+
intron-3CDSENST00000474356ENST00000396392PIP5K1Bchr9

71555706

+PGM5chr9

71080009

+
intron-3CDSENST00000474356ENST00000396392PIP5K1Bchr9

71437599

+PGM5chr9

71080009

+
intron-3CDSENST00000474356ENST00000396392PIP5K1Bchr9

71437599

+PGM5chr9

71080008

+
intron-3CDSENST00000474356ENST00000396396PIP5K1Bchr9

71555706

+PGM5chr9

71080009

+
intron-3CDSENST00000474356ENST00000396396PIP5K1Bchr9

71437599

+PGM5chr9

71080009

+
intron-3CDSENST00000474356ENST00000396396PIP5K1Bchr9

71437599

+PGM5chr9

71080008

+
intron-intronENST00000474356ENST00000396392PIP5K1Bchr9

71491710

+PGM5chr9

71094334

+
intron-intronENST00000474356ENST00000396392PIP5K1Bchr9

71491710

+PGM5chr9

71094333

+
intron-intronENST00000474356ENST00000396396PIP5K1Bchr9

71491710

+PGM5chr9

71094334

+
intron-intronENST00000474356ENST00000396396PIP5K1Bchr9

71491710

+PGM5chr9

71094333

+
intron-intronENST00000474356ENST00000604870PIP5K1Bchr9

71555706

+PGM5chr9

71080009

+
intron-intronENST00000474356ENST00000604870PIP5K1Bchr9

71491710

+PGM5chr9

71094334

+
intron-intronENST00000474356ENST00000604870PIP5K1Bchr9

71491710

+PGM5chr9

71094333

+
intron-intronENST00000474356ENST00000604870PIP5K1Bchr9

71437599

+PGM5chr9

71080009

+
intron-intronENST00000474356ENST00000604870PIP5K1Bchr9

71437599

+PGM5chr9

71080008

+

check buttonORFfinder result based on the fusion transcript sequence of in-frame fusion genes.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandSeq length
(transcript)		BP loci
(transcript)		Predicted start
(transcript)		Predicted stop
(transcript)		Seq length
(amino acids)
ENST00000541509PIP5K1Bchr971555706+ENST00000396392PGM5chr971080009+220116911891811540
ENST00000541509PIP5K1Bchr971555706+ENST00000396396PGM5chr971080009+375716911892351720
ENST00000265382PIP5K1Bchr971555706+ENST00000396392PGM5chr971080009+231718073051927540
ENST00000265382PIP5K1Bchr971555706+ENST00000396396PGM5chr971080009+387318073052467720

check buttonDeepORF prediction of the coding potential based on the fusion transcript sequence of in-frame fusion genes. DeepORF is a coding potential classifier based on convolutional neural network by comparing the real Ribo-seq data. If the no-coding score < 0.5 and coding score > 0.5, then the in-frame fusion transcript is predicted as being likely translated.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandNo-coding scoreCoding score
ENST00000541509ENST00000396392PIP5K1Bchr971555706+PGM5chr971080009+0.0008181810.9991818
ENST00000541509ENST00000396396PIP5K1Bchr971555706+PGM5chr971080009+0.0012865370.9987135
ENST00000265382ENST00000396392PIP5K1Bchr971555706+PGM5chr971080009+0.0009367790.9990632
ENST00000265382ENST00000396396PIP5K1Bchr971555706+PGM5chr971080009+0.0013929810.9986071

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Fusion Genomic Features for PIP5K1B-PGM5


check buttonFusionAI prediction of the potential fusion gene breakpoint based on the pre-mature RNA sequence context (+/- 5kb of individual partner genes, total 20kb length sequence). FusionAI is a fusion gene breakpoint classifier based on convolutional neural network by comparing the fusion positive and negative sequence context of ~ 20K fusion gene data. From here, we can have the relative potentency of the 20K genomic sequence how individual sequnce will be likely used as the gene fusion breakpoints.
HgeneHchrHbpHstrandTgeneTchrTbpTstrand1-pp (fusion gene breakpoint)
PIP5K1Bchr971491710+PGM5chr971094333+0.0003555290.9996445
PIP5K1Bchr971491710+PGM5chr971094333+0.0003555290.9996445
PIP5K1Bchr971555706+PGM5chr971080008+0.0003229710.99967706
PIP5K1Bchr971437599+PGM5chr971080008+0.000110750.99988925
PIP5K1Bchr971437599+PGM5chr971080008+0.000110750.99988925
PIP5K1Bchr971491710+PGM5chr971094333+0.0003555290.9996445
PIP5K1Bchr971491710+PGM5chr971094333+0.0003555290.9996445
PIP5K1Bchr971555706+PGM5chr971080008+0.0003229710.99967706
PIP5K1Bchr971437599+PGM5chr971080008+0.000110750.99988925
PIP5K1Bchr971437599+PGM5chr971080008+0.000110750.99988925

check buttonDistribution of 44 human genomic features loci across 20kb length fusion breakpoint regions. We integrated a total of 44 different types of human genomic feature loci information across five big categories including virus integration sites, repeats, structural variants, chromatin states, and gene expression regulation. More details are in help page.
genomic feature

check buttonDistribution of 44 human genomic features loci across 20kb length fusion breakpoint regions that are ovelapped with the top 1% feature importance score regions. More details are in help page.
genomic feature of top 1%

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Fusion Protein Features for PIP5K1B-PGM5


check button Four levels of functional features of fusion genes
Go to FGviewer search page for the most frequent breakpoint (https://ccsmweb.uth.edu/FGviewer/chr9:71491710/chr9:71094334)
- FGviewer provides the online visualization of the retention search of the protein functional features across DNA, RNA, protein, and pathological levels.
- How to search
1. Put your fusion gene symbol.
2. Press the tab key until there will be shown the breakpoint information filled.
4. Go down and press 'Search' tab twice.
4. Go down to have the hyperlink of the search result.
5. Click the hyperlink.
6. See the FGviewer result for your fusion gene.
FGviewer

check buttonMain function of each fusion partner protein. (from UniProt)
HgeneTgene
..
FUNCTION: Transcriptional activator which is required for calcium-dependent dendritic growth and branching in cortical neurons. Recruits CREB-binding protein (CREBBP) to nuclear bodies. Component of the CREST-BRG1 complex, a multiprotein complex that regulates promoter activation by orchestrating a calcium-dependent release of a repressor complex and a recruitment of an activator complex. In resting neurons, transcription of the c-FOS promoter is inhibited by BRG1-dependent recruitment of a phospho-RB1-HDAC1 repressor complex. Upon calcium influx, RB1 is dephosphorylated by calcineurin, which leads to release of the repressor complex. At the same time, there is increased recruitment of CREBBP to the promoter by a CREST-dependent mechanism, which leads to transcriptional activation. The CREST-BRG1 complex also binds to the NR2B promoter, and activity-dependent induction of NR2B expression involves a release of HDAC1 and recruitment of CREBBP (By similarity). {ECO:0000250}.FUNCTION: Transcriptional activator which is required for calcium-dependent dendritic growth and branching in cortical neurons. Recruits CREB-binding protein (CREBBP) to nuclear bodies. Component of the CREST-BRG1 complex, a multiprotein complex that regulates promoter activation by orchestrating a calcium-dependent release of a repressor complex and a recruitment of an activator complex. In resting neurons, transcription of the c-FOS promoter is inhibited by BRG1-dependent recruitment of a phospho-RB1-HDAC1 repressor complex. Upon calcium influx, RB1 is dephosphorylated by calcineurin, which leads to release of the repressor complex. At the same time, there is increased recruitment of CREBBP to the promoter by a CREST-dependent mechanism, which leads to transcriptional activation. The CREST-BRG1 complex also binds to the NR2B promoter, and activity-dependent induction of NR2B expression involves a release of HDAC1 and recruitment of CREBBP (By similarity). {ECO:0000250}.

check buttonRetention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at

download page


* Minus value of BPloci means that the break pointn is located before the CDS.
- In-frame and retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
HgenePIP5K1Bchr9:71555706chr9:71080009ENST00000265382+141625_395500541.0DomainPIPK
TgenePGM5chr9:71555706chr9:71080009ENST0000039639258510_513347388.0Compositional biasNote=Poly-Ser
TgenePGM5chr9:71555706chr9:71080009ENST00000396396511510_513347568.0Compositional biasNote=Poly-Ser
TgenePGM5chr9:71555706chr9:71080009ENST0000039639258381_383347388.0RegionSubstrate binding
TgenePGM5chr9:71555706chr9:71080009ENST00000396396511381_383347568.0RegionSubstrate binding

- In-frame and not-retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
TgenePGM5chr9:71555706chr9:71080009ENST0000039639258122_123347388.0RegionSubstrate binding
TgenePGM5chr9:71555706chr9:71080009ENST0000039639258297_298347388.0RegionSubstrate binding
TgenePGM5chr9:71555706chr9:71080009ENST00000396396511122_123347568.0RegionSubstrate binding
TgenePGM5chr9:71555706chr9:71080009ENST00000396396511297_298347568.0RegionSubstrate binding


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Fusion Gene Sequence for PIP5K1B-PGM5


check button For in-frame fusion transcripts, we provide the fusion transcript sequences and fusion amino acid sequences. To have fusion amino acid sequence, we ran ORFfinder and chose the longest ORF among the all predicted ones.
>65519_65519_1_PIP5K1B-PGM5_PIP5K1B_chr9_71555706_ENST00000265382_PGM5_chr9_71080009_ENST00000396392_length(transcript)=2317nt_BP=1807nt
AACTTGCAGACTGTGGCGCAACTGGTCTTGGTAGCGGAGGCACCCGAATGCTGCCCGGGTGAGATGAGGAAGCCAAGGCCCAGCAGAGCT
GAGATGTGACTGCAGAGCCGTCCAACCCCAGTCCTGTGACCTTTCTCTGGTGCCTGATACCTCTCAGCATTTGAGGGCCTTTTCTCTTCC
TGCTTCATCTCTAAAGGTCCTTCTAGGAGAGAGGTGAAAGAAACCTGGCAAAGAAAACGGTCTCGACAATGAGTAGGCCACCCATCACTA
CTAACTACAGATGACTTGCCATTTCATTTACAAAGATGTCTTCTGCTGCTGAAAATGGAGAGGCAGCACCTGGAAAACAAAATGAAGAAA
AAACCTATAAAAAGACTGCATCATCTGCTATTAAAGGTGCTATTCAGCTGGGAATAGGATACACAGTGGGTAATCTCACTTCCAAGCCAG
AACGAGATGTTCTTATGCAAGACTTTTATGTGGTGGAAAGTGTGTTCCTACCCAGCGAAGGGAGCAATCTGACCCCAGCACATCACTACC
CAGACTTTAGATTTAAGACATACGCTCCATTAGCATTCCGATATTTCAGAGAACTTTTTGGTATCAAGCCTGATGATTACTTGTATTCCA
TCTGCAGTGAACCTCTAATAGAACTGTCTAACCCTGGAGCCAGTGGATCCTTGTTTTTTGTGACCAGTGATGATGAATTTATCATCAAAA
CAGTTCAGCACAAAGAAGCTGAGTTTCTTCAGAAGCTACTGCCAGGCTATTACATGAATTTAAACCAGAATCCAAGGACTCTTTTGCCAA
AATTTTACGGACTGTATTGTATGCAATCAGGAGGCATTAATATCAGGATTGTGGTGATGAACAACGTTTTGCCACGCTCCATGAGAATGC
ACTTTACATATGACTTGAAAGGCTCAACGTATAAGCGAAGAGCATCCCGTAAAGAGAGAGAGAAATCCAACCCCACATTTAAGGACTTAG
ATTTCCTGCAAGACATGCACGAAGGGTTGTATTTTGATACGGAAACATACAACGCGCTTATGAAAACACTTCAGAGAGACTGCCGGGTGC
TAGAAAGCTTCAAGATCATGGATTATAGCCTTCTGTTGGGAATTCATTTCCTGGACCATTCCCTCAAAGAGAAAGAGGAGGAGACCCCAC
AAAATGTGCCTGATGCTAAGCGGACTGGGATGCAGAAGGTTCTCTACTCAACAGCCATGGAATCTATCCAGGGTCCAGGGAAATCTGGAG
ATGGGATAATCACAGAGAACCCAGACACAATGGGAGGCATTCCAGCTAAAAGCCATAGGGGAGAAAAACTACTTTTATTTATGGGCATTA
TTGACATTCTGCAATCATATAGGTTAATGAAGAAGTTAGAACATTCCTGGAAAGCTCTTGTTTATGATGGGGACACTGTTTCTGTTCATA
GACCAAGCTTTTATGCAGACAGATTTCTTAAGTTCATGAATTCCAGAGTTTTCAAGAAAATTCAAGCTTTGAAGGCTTCACCGTCTAAGA
AACGGTGCAATTCAATCGCCGCCCTAAAGGCCACTTCACAGGAGATTGTGTCCTCAATTAGCCAGGAATGGAAGGATGAGAAGCGGGATT
TGCTGACTGAAGGACAAAGTTTTAGCAGCCTTGATGAAGAAGCCCTGGGATCCCGACACAGGCCAGACCTGGTCCCTAGCACTCCATCAC
TGTTTGAAGCTGCTTCCTTGGCAACCACAATTTCATCTTCTTCCTTATACGTCAATGAGCACTATCCACACGACAGGCCTACACTCTATT
CAAACAGAGTGGCCAAATCAATGAAGGTCCCTGTATATGAGACCCCAGCTGGATGGAGATTCTTCTCAAATCTGATGGACTCAGGACGTT
GCAATCTGTGTGGGGAAGAGAGCTTTGGCACTGTTTAGATCGTCTCTATTGGAACATCTTTAAGTTCACTGATTCTTTCCTTAGCTGTGT
CCAATCTGCTGATGAGCCTGTTGAAGGAATTCTTCTTCTCCGATACTGTGTGTTTTTTTTTTTTTTTTAGCATTTCTCTTTGACTCTTTT
AAAATAGTTTTTAGTTCTCTGAAATTCCCCATCTGTTTATGTAATTGTTTATCTTTTTCATTAGATCATTTAACATATTAGACATGGTTG
TTTTAAACACCCTGTCTGATAGTTCCAATCTCTGGTTCATCTCTGACTTTGGTTCAGCTGATTGCTTTATCTCTTGACAATGGTTTGGGT

>65519_65519_1_PIP5K1B-PGM5_PIP5K1B_chr9_71555706_ENST00000265382_PGM5_chr9_71080009_ENST00000396392_length(amino acids)=540AA_BP=500
MSSAAENGEAAPGKQNEEKTYKKTASSAIKGAIQLGIGYTVGNLTSKPERDVLMQDFYVVESVFLPSEGSNLTPAHHYPDFRFKTYAPLA
FRYFRELFGIKPDDYLYSICSEPLIELSNPGASGSLFFVTSDDEFIIKTVQHKEAEFLQKLLPGYYMNLNQNPRTLLPKFYGLYCMQSGG
INIRIVVMNNVLPRSMRMHFTYDLKGSTYKRRASRKEREKSNPTFKDLDFLQDMHEGLYFDTETYNALMKTLQRDCRVLESFKIMDYSLL
LGIHFLDHSLKEKEEETPQNVPDAKRTGMQKVLYSTAMESIQGPGKSGDGIITENPDTMGGIPAKSHRGEKLLLFMGIIDILQSYRLMKK
LEHSWKALVYDGDTVSVHRPSFYADRFLKFMNSRVFKKIQALKASPSKKRCNSIAALKATSQEIVSSISQEWKDEKRDLLTEGQSFSSLD
EEALGSRHRPDLVPSTPSLFEAASLATTISSSSLYVNEHYPHDRPTLYSNRVAKSMKVPVYETPAGWRFFSNLMDSGRCNLCGEESFGTV

--------------------------------------------------------------
>65519_65519_2_PIP5K1B-PGM5_PIP5K1B_chr9_71555706_ENST00000265382_PGM5_chr9_71080009_ENST00000396396_length(transcript)=3873nt_BP=1807nt
AACTTGCAGACTGTGGCGCAACTGGTCTTGGTAGCGGAGGCACCCGAATGCTGCCCGGGTGAGATGAGGAAGCCAAGGCCCAGCAGAGCT
GAGATGTGACTGCAGAGCCGTCCAACCCCAGTCCTGTGACCTTTCTCTGGTGCCTGATACCTCTCAGCATTTGAGGGCCTTTTCTCTTCC
TGCTTCATCTCTAAAGGTCCTTCTAGGAGAGAGGTGAAAGAAACCTGGCAAAGAAAACGGTCTCGACAATGAGTAGGCCACCCATCACTA
CTAACTACAGATGACTTGCCATTTCATTTACAAAGATGTCTTCTGCTGCTGAAAATGGAGAGGCAGCACCTGGAAAACAAAATGAAGAAA
AAACCTATAAAAAGACTGCATCATCTGCTATTAAAGGTGCTATTCAGCTGGGAATAGGATACACAGTGGGTAATCTCACTTCCAAGCCAG
AACGAGATGTTCTTATGCAAGACTTTTATGTGGTGGAAAGTGTGTTCCTACCCAGCGAAGGGAGCAATCTGACCCCAGCACATCACTACC
CAGACTTTAGATTTAAGACATACGCTCCATTAGCATTCCGATATTTCAGAGAACTTTTTGGTATCAAGCCTGATGATTACTTGTATTCCA
TCTGCAGTGAACCTCTAATAGAACTGTCTAACCCTGGAGCCAGTGGATCCTTGTTTTTTGTGACCAGTGATGATGAATTTATCATCAAAA
CAGTTCAGCACAAAGAAGCTGAGTTTCTTCAGAAGCTACTGCCAGGCTATTACATGAATTTAAACCAGAATCCAAGGACTCTTTTGCCAA
AATTTTACGGACTGTATTGTATGCAATCAGGAGGCATTAATATCAGGATTGTGGTGATGAACAACGTTTTGCCACGCTCCATGAGAATGC
ACTTTACATATGACTTGAAAGGCTCAACGTATAAGCGAAGAGCATCCCGTAAAGAGAGAGAGAAATCCAACCCCACATTTAAGGACTTAG
ATTTCCTGCAAGACATGCACGAAGGGTTGTATTTTGATACGGAAACATACAACGCGCTTATGAAAACACTTCAGAGAGACTGCCGGGTGC
TAGAAAGCTTCAAGATCATGGATTATAGCCTTCTGTTGGGAATTCATTTCCTGGACCATTCCCTCAAAGAGAAAGAGGAGGAGACCCCAC
AAAATGTGCCTGATGCTAAGCGGACTGGGATGCAGAAGGTTCTCTACTCAACAGCCATGGAATCTATCCAGGGTCCAGGGAAATCTGGAG
ATGGGATAATCACAGAGAACCCAGACACAATGGGAGGCATTCCAGCTAAAAGCCATAGGGGAGAAAAACTACTTTTATTTATGGGCATTA
TTGACATTCTGCAATCATATAGGTTAATGAAGAAGTTAGAACATTCCTGGAAAGCTCTTGTTTATGATGGGGACACTGTTTCTGTTCATA
GACCAAGCTTTTATGCAGACAGATTTCTTAAGTTCATGAATTCCAGAGTTTTCAAGAAAATTCAAGCTTTGAAGGCTTCACCGTCTAAGA
AACGGTGCAATTCAATCGCCGCCCTAAAGGCCACTTCACAGGAGATTGTGTCCTCAATTAGCCAGGAATGGAAGGATGAGAAGCGGGATT
TGCTGACTGAAGGACAAAGTTTTAGCAGCCTTGATGAAGAAGCCCTGGGATCCCGACACAGGCCAGACCTGGTCCCTAGCACTCCATCAC
TGTTTGAAGCTGCTTCCTTGGCAACCACAATTTCATCTTCTTCCTTATACGTCAATGAGCACTATCCACACGACAGGCCTACACTCTATT
CAAACAGAGTGGCCAAATCAATGAAGGTCCCTGTATATGAGACCCCAGCTGGATGGAGATTCTTCTCAAATCTGATGGACTCAGGACGTT
GCAATCTGTGTGGGGAAGAGAGCTTTGGCACTGGCTCTGACCACCTCCGAGAGAAGGATGGCCTGTGGGCTGTCTTGGTCTGGCTCTCCA
TTATTGCTGCCCGGAAGCAGAGTGTGGAGGAAATTGTCCGAGATCACTGGGCCAAATTTGGCCGCCACTACTATTGCAGGTTTGACTATG
AGGGGTTGGATCCCAAGACGACATATTATATCATGAGGGACCTGGAGGCCCTGGTCACAGACAAATCCTTCATTGGCCAGCAGTTTGCTG
TGGGGAGCCATGTCTACAGCGTGGCGAAGACGGATAGTTTTGAATACGTGGACCCTGTGGATGGCACTGTGACCAAGAAACAGGGCCTAA
GGATCATTTTCTCGGATGCATCACGGCTCATCTTCCGGCTCAGTTCCTCCAGTGGTGTGCGGGCCACCCTCAGACTGTACGCAGAGAGCT
ACGAGAGGGATCCCAGCGGCCATGACCAGGAGCCACAGGCAGTGCTGAGCCCTCTCATAGCCATCGCACTGAAAATATCCCAGATTCATG
AGAGAACTGGCCGGAGGGGACCCACTGTCATCACCTGAATAGAGGAAAGATCACTCACCAGGGCCAAAGAGAGTGCTCAGCGGGAGATGC
TTCACTGATGCCTTCTTGCTACCTGTTTGTGCCTCTTATGACTTTGGAAAAACAAAAGATATTTTGCTTTTGGGGGATAGAGGGTGGGTG
GGAAAAGAAAAAAAATCCATTTGGTTTTGGTTTTGTCCTATTCCTCCAAATGCAGCAGGGCCTTTAGTTGTCTGTTAAAGCTGCACTATA
ATTTGGTATCTACATTTTATCACACAAAGGAACCTCCCCTTTTGACAACAACTGGGCTAGGCAGCTGTTAATCACAACATTTGTGCATCA
CTTGTGCCAAGTGAGAAAATGTTCTAAAATCACAAGAGAGAACAGTGCCAGAATGAAACTGACCCTAAGTCCCAGGTGCCCCTGGGCAGG
CAGAAGGAGACACTCCCAGCATGGAGGAGGGTTTATCTTTTCATCCTAGGTCAGGTCTACAATGGGGGAAGGTTTTATTATAGAACTCCC
AACAGCCCACCTCACTCCTGCCACCCACCCGATGGCCCTGCCTCCCCCATCCCATCCCCAACATCCCTGTACCACCTTCTCTCACATCTT
CTAAAGCTTTGTACAAATCACAATGGTGCACTTCCAACAAAATATATCAATAGGTGTTTTCCTCTCTTATTTTGTAAATAGTATTATTTT
AGCTATTAAGCTGGATACCTTCTTTCAAATTCAGCCATTCAGTTGTAAAGTTGGGAAGAAGTTTCTTGACAAGACTCTGCAATTAAATGC
TTAAAATTTGGAGGGGATCCTTCCTTGATTACATCAAGTATGTTGGTACATGGGTTTATACAAGTTCCTCTTGAGAAGGCAAAAAGACCA
CCATGTGTGAGAGCTCTTTGACTTGGCCAATAGGGGCCTATCTTAATGCACTTGTTTGGACACATTTCTGATCTTATTTGTAAAGGCTGC
AAAAGGAGAGGATGAAATGCTGTAAAAGTAGGAAATGAAGTGGAAGCTGGAAGAAAATGTAATTGGTGGTACAGCTATGGGCCAGATGGT
GGAGGGGAGGGTGGGGACCCCTGCCGGCAAGCAGAGTGTCACAGCTGGCTTTCCTCACTTGGGAAAAGGGTACTGCCGGTCTAGCAGCCT
CCTCTGTACTCAGCCAGGACACCCAGCGCGTGGGACCTGTTTGTGTCTGTTTTGCTTCCTTGGGAACGGCACAGTCACTCACCCTGCCAT
TTGCGGAAATGACCTGGTGCACTTTGACTGTTAAGCAATGCGTTATTGCTGTAGTCAAGGTTAGTGCAAGCAAGGAAACATTCCCAGTAA
GGTATTTGTTTCCATTTTCTGTCTGTGCTTCTGTCAGAAACTTGCTAGGACATTTAGTGGCCAATAAAAAAGAAATTCCTAATTTCAACC

>65519_65519_2_PIP5K1B-PGM5_PIP5K1B_chr9_71555706_ENST00000265382_PGM5_chr9_71080009_ENST00000396396_length(amino acids)=720AA_BP=500
MSSAAENGEAAPGKQNEEKTYKKTASSAIKGAIQLGIGYTVGNLTSKPERDVLMQDFYVVESVFLPSEGSNLTPAHHYPDFRFKTYAPLA
FRYFRELFGIKPDDYLYSICSEPLIELSNPGASGSLFFVTSDDEFIIKTVQHKEAEFLQKLLPGYYMNLNQNPRTLLPKFYGLYCMQSGG
INIRIVVMNNVLPRSMRMHFTYDLKGSTYKRRASRKEREKSNPTFKDLDFLQDMHEGLYFDTETYNALMKTLQRDCRVLESFKIMDYSLL
LGIHFLDHSLKEKEEETPQNVPDAKRTGMQKVLYSTAMESIQGPGKSGDGIITENPDTMGGIPAKSHRGEKLLLFMGIIDILQSYRLMKK
LEHSWKALVYDGDTVSVHRPSFYADRFLKFMNSRVFKKIQALKASPSKKRCNSIAALKATSQEIVSSISQEWKDEKRDLLTEGQSFSSLD
EEALGSRHRPDLVPSTPSLFEAASLATTISSSSLYVNEHYPHDRPTLYSNRVAKSMKVPVYETPAGWRFFSNLMDSGRCNLCGEESFGTG
SDHLREKDGLWAVLVWLSIIAARKQSVEEIVRDHWAKFGRHYYCRFDYEGLDPKTTYYIMRDLEALVTDKSFIGQQFAVGSHVYSVAKTD
SFEYVDPVDGTVTKKQGLRIIFSDASRLIFRLSSSSGVRATLRLYAESYERDPSGHDQEPQAVLSPLIAIALKISQIHERTGRRGPTVIT

--------------------------------------------------------------
>65519_65519_3_PIP5K1B-PGM5_PIP5K1B_chr9_71555706_ENST00000541509_PGM5_chr9_71080009_ENST00000396392_length(transcript)=2201nt_BP=1691nt
ACTGCTCTCCCTTCGCTGTGGGGAAGCGACAACGTCCCGATAACTTGCAGACTGTGGCGCAACTGGTCTTGGTAGCGGAGGCACCCGAAT
GCTGCCCGGGTGAGAAACCTGGCAAAGAAAACGGTCTCGACAATGAGTAGGCCACCCATCACTACTAACTACAGATGACTTGCCATTTCA
TTTACAAAGATGTCTTCTGCTGCTGAAAATGGAGAGGCAGCACCTGGAAAACAAAATGAAGAAAAAACCTATAAAAAGACTGCATCATCT
GCTATTAAAGGTGCTATTCAGCTGGGAATAGGATACACAGTGGGTAATCTCACTTCCAAGCCAGAACGAGATGTTCTTATGCAAGACTTT
TATGTGGTGGAAAGTGTGTTCCTACCCAGCGAAGGGAGCAATCTGACCCCAGCACATCACTACCCAGACTTTAGATTTAAGACATACGCT
CCATTAGCATTCCGATATTTCAGAGAACTTTTTGGTATCAAGCCTGATGATTACTTGTATTCCATCTGCAGTGAACCTCTAATAGAACTG
TCTAACCCTGGAGCCAGTGGATCCTTGTTTTTTGTGACCAGTGATGATGAATTTATCATCAAAACAGTTCAGCACAAAGAAGCTGAGTTT
CTTCAGAAGCTACTGCCAGGCTATTACATGAATTTAAACCAGAATCCAAGGACTCTTTTGCCAAAATTTTACGGACTGTATTGTATGCAA
TCAGGAGGCATTAATATCAGGATTGTGGTGATGAACAACGTTTTGCCACGCTCCATGAGAATGCACTTTACATATGACTTGAAAGGCTCA
ACGTATAAGCGAAGAGCATCCCGTAAAGAGAGAGAGAAATCCAACCCCACATTTAAGGACTTAGATTTCCTGCAAGACATGCACGAAGGG
TTGTATTTTGATACGGAAACATACAACGCGCTTATGAAAACACTTCAGAGAGACTGCCGGGTGCTAGAAAGCTTCAAGATCATGGATTAT
AGCCTTCTGTTGGGAATTCATTTCCTGGACCATTCCCTCAAAGAGAAAGAGGAGGAGACCCCACAAAATGTGCCTGATGCTAAGCGGACT
GGGATGCAGAAGGTTCTCTACTCAACAGCCATGGAATCTATCCAGGGTCCAGGGAAATCTGGAGATGGGATAATCACAGAGAACCCAGAC
ACAATGGGAGGCATTCCAGCTAAAAGCCATAGGGGAGAAAAACTACTTTTATTTATGGGCATTATTGACATTCTGCAATCATATAGGTTA
ATGAAGAAGTTAGAACATTCCTGGAAAGCTCTTGTTTATGATGGGGACACTGTTTCTGTTCATAGACCAAGCTTTTATGCAGACAGATTT
CTTAAGTTCATGAATTCCAGAGTTTTCAAGAAAATTCAAGCTTTGAAGGCTTCACCGTCTAAGAAACGGTGCAATTCAATCGCCGCCCTA
AAGGCCACTTCACAGGAGATTGTGTCCTCAATTAGCCAGGAATGGAAGGATGAGAAGCGGGATTTGCTGACTGAAGGACAAAGTTTTAGC
AGCCTTGATGAAGAAGCCCTGGGATCCCGACACAGGCCAGACCTGGTCCCTAGCACTCCATCACTGTTTGAAGCTGCTTCCTTGGCAACC
ACAATTTCATCTTCTTCCTTATACGTCAATGAGCACTATCCACACGACAGGCCTACACTCTATTCAAACAGAGTGGCCAAATCAATGAAG
GTCCCTGTATATGAGACCCCAGCTGGATGGAGATTCTTCTCAAATCTGATGGACTCAGGACGTTGCAATCTGTGTGGGGAAGAGAGCTTT
GGCACTGTTTAGATCGTCTCTATTGGAACATCTTTAAGTTCACTGATTCTTTCCTTAGCTGTGTCCAATCTGCTGATGAGCCTGTTGAAG
GAATTCTTCTTCTCCGATACTGTGTGTTTTTTTTTTTTTTTTAGCATTTCTCTTTGACTCTTTTAAAATAGTTTTTAGTTCTCTGAAATT
CCCCATCTGTTTATGTAATTGTTTATCTTTTTCATTAGATCATTTAACATATTAGACATGGTTGTTTTAAACACCCTGTCTGATAGTTCC
AATCTCTGGTTCATCTCTGACTTTGGTTCAGCTGATTGCTTTATCTCTTGACAATGGTTTGGGTTTTCCTGTTTTTTGTAGATCTCATAA

>65519_65519_3_PIP5K1B-PGM5_PIP5K1B_chr9_71555706_ENST00000541509_PGM5_chr9_71080009_ENST00000396392_length(amino acids)=540AA_BP=500
MSSAAENGEAAPGKQNEEKTYKKTASSAIKGAIQLGIGYTVGNLTSKPERDVLMQDFYVVESVFLPSEGSNLTPAHHYPDFRFKTYAPLA
FRYFRELFGIKPDDYLYSICSEPLIELSNPGASGSLFFVTSDDEFIIKTVQHKEAEFLQKLLPGYYMNLNQNPRTLLPKFYGLYCMQSGG
INIRIVVMNNVLPRSMRMHFTYDLKGSTYKRRASRKEREKSNPTFKDLDFLQDMHEGLYFDTETYNALMKTLQRDCRVLESFKIMDYSLL
LGIHFLDHSLKEKEEETPQNVPDAKRTGMQKVLYSTAMESIQGPGKSGDGIITENPDTMGGIPAKSHRGEKLLLFMGIIDILQSYRLMKK
LEHSWKALVYDGDTVSVHRPSFYADRFLKFMNSRVFKKIQALKASPSKKRCNSIAALKATSQEIVSSISQEWKDEKRDLLTEGQSFSSLD
EEALGSRHRPDLVPSTPSLFEAASLATTISSSSLYVNEHYPHDRPTLYSNRVAKSMKVPVYETPAGWRFFSNLMDSGRCNLCGEESFGTV

--------------------------------------------------------------
>65519_65519_4_PIP5K1B-PGM5_PIP5K1B_chr9_71555706_ENST00000541509_PGM5_chr9_71080009_ENST00000396396_length(transcript)=3757nt_BP=1691nt
ACTGCTCTCCCTTCGCTGTGGGGAAGCGACAACGTCCCGATAACTTGCAGACTGTGGCGCAACTGGTCTTGGTAGCGGAGGCACCCGAAT
GCTGCCCGGGTGAGAAACCTGGCAAAGAAAACGGTCTCGACAATGAGTAGGCCACCCATCACTACTAACTACAGATGACTTGCCATTTCA
TTTACAAAGATGTCTTCTGCTGCTGAAAATGGAGAGGCAGCACCTGGAAAACAAAATGAAGAAAAAACCTATAAAAAGACTGCATCATCT
GCTATTAAAGGTGCTATTCAGCTGGGAATAGGATACACAGTGGGTAATCTCACTTCCAAGCCAGAACGAGATGTTCTTATGCAAGACTTT
TATGTGGTGGAAAGTGTGTTCCTACCCAGCGAAGGGAGCAATCTGACCCCAGCACATCACTACCCAGACTTTAGATTTAAGACATACGCT
CCATTAGCATTCCGATATTTCAGAGAACTTTTTGGTATCAAGCCTGATGATTACTTGTATTCCATCTGCAGTGAACCTCTAATAGAACTG
TCTAACCCTGGAGCCAGTGGATCCTTGTTTTTTGTGACCAGTGATGATGAATTTATCATCAAAACAGTTCAGCACAAAGAAGCTGAGTTT
CTTCAGAAGCTACTGCCAGGCTATTACATGAATTTAAACCAGAATCCAAGGACTCTTTTGCCAAAATTTTACGGACTGTATTGTATGCAA
TCAGGAGGCATTAATATCAGGATTGTGGTGATGAACAACGTTTTGCCACGCTCCATGAGAATGCACTTTACATATGACTTGAAAGGCTCA
ACGTATAAGCGAAGAGCATCCCGTAAAGAGAGAGAGAAATCCAACCCCACATTTAAGGACTTAGATTTCCTGCAAGACATGCACGAAGGG
TTGTATTTTGATACGGAAACATACAACGCGCTTATGAAAACACTTCAGAGAGACTGCCGGGTGCTAGAAAGCTTCAAGATCATGGATTAT
AGCCTTCTGTTGGGAATTCATTTCCTGGACCATTCCCTCAAAGAGAAAGAGGAGGAGACCCCACAAAATGTGCCTGATGCTAAGCGGACT
GGGATGCAGAAGGTTCTCTACTCAACAGCCATGGAATCTATCCAGGGTCCAGGGAAATCTGGAGATGGGATAATCACAGAGAACCCAGAC
ACAATGGGAGGCATTCCAGCTAAAAGCCATAGGGGAGAAAAACTACTTTTATTTATGGGCATTATTGACATTCTGCAATCATATAGGTTA
ATGAAGAAGTTAGAACATTCCTGGAAAGCTCTTGTTTATGATGGGGACACTGTTTCTGTTCATAGACCAAGCTTTTATGCAGACAGATTT
CTTAAGTTCATGAATTCCAGAGTTTTCAAGAAAATTCAAGCTTTGAAGGCTTCACCGTCTAAGAAACGGTGCAATTCAATCGCCGCCCTA
AAGGCCACTTCACAGGAGATTGTGTCCTCAATTAGCCAGGAATGGAAGGATGAGAAGCGGGATTTGCTGACTGAAGGACAAAGTTTTAGC
AGCCTTGATGAAGAAGCCCTGGGATCCCGACACAGGCCAGACCTGGTCCCTAGCACTCCATCACTGTTTGAAGCTGCTTCCTTGGCAACC
ACAATTTCATCTTCTTCCTTATACGTCAATGAGCACTATCCACACGACAGGCCTACACTCTATTCAAACAGAGTGGCCAAATCAATGAAG
GTCCCTGTATATGAGACCCCAGCTGGATGGAGATTCTTCTCAAATCTGATGGACTCAGGACGTTGCAATCTGTGTGGGGAAGAGAGCTTT
GGCACTGGCTCTGACCACCTCCGAGAGAAGGATGGCCTGTGGGCTGTCTTGGTCTGGCTCTCCATTATTGCTGCCCGGAAGCAGAGTGTG
GAGGAAATTGTCCGAGATCACTGGGCCAAATTTGGCCGCCACTACTATTGCAGGTTTGACTATGAGGGGTTGGATCCCAAGACGACATAT
TATATCATGAGGGACCTGGAGGCCCTGGTCACAGACAAATCCTTCATTGGCCAGCAGTTTGCTGTGGGGAGCCATGTCTACAGCGTGGCG
AAGACGGATAGTTTTGAATACGTGGACCCTGTGGATGGCACTGTGACCAAGAAACAGGGCCTAAGGATCATTTTCTCGGATGCATCACGG
CTCATCTTCCGGCTCAGTTCCTCCAGTGGTGTGCGGGCCACCCTCAGACTGTACGCAGAGAGCTACGAGAGGGATCCCAGCGGCCATGAC
CAGGAGCCACAGGCAGTGCTGAGCCCTCTCATAGCCATCGCACTGAAAATATCCCAGATTCATGAGAGAACTGGCCGGAGGGGACCCACT
GTCATCACCTGAATAGAGGAAAGATCACTCACCAGGGCCAAAGAGAGTGCTCAGCGGGAGATGCTTCACTGATGCCTTCTTGCTACCTGT
TTGTGCCTCTTATGACTTTGGAAAAACAAAAGATATTTTGCTTTTGGGGGATAGAGGGTGGGTGGGAAAAGAAAAAAAATCCATTTGGTT
TTGGTTTTGTCCTATTCCTCCAAATGCAGCAGGGCCTTTAGTTGTCTGTTAAAGCTGCACTATAATTTGGTATCTACATTTTATCACACA
AAGGAACCTCCCCTTTTGACAACAACTGGGCTAGGCAGCTGTTAATCACAACATTTGTGCATCACTTGTGCCAAGTGAGAAAATGTTCTA
AAATCACAAGAGAGAACAGTGCCAGAATGAAACTGACCCTAAGTCCCAGGTGCCCCTGGGCAGGCAGAAGGAGACACTCCCAGCATGGAG
GAGGGTTTATCTTTTCATCCTAGGTCAGGTCTACAATGGGGGAAGGTTTTATTATAGAACTCCCAACAGCCCACCTCACTCCTGCCACCC
ACCCGATGGCCCTGCCTCCCCCATCCCATCCCCAACATCCCTGTACCACCTTCTCTCACATCTTCTAAAGCTTTGTACAAATCACAATGG
TGCACTTCCAACAAAATATATCAATAGGTGTTTTCCTCTCTTATTTTGTAAATAGTATTATTTTAGCTATTAAGCTGGATACCTTCTTTC
AAATTCAGCCATTCAGTTGTAAAGTTGGGAAGAAGTTTCTTGACAAGACTCTGCAATTAAATGCTTAAAATTTGGAGGGGATCCTTCCTT
GATTACATCAAGTATGTTGGTACATGGGTTTATACAAGTTCCTCTTGAGAAGGCAAAAAGACCACCATGTGTGAGAGCTCTTTGACTTGG
CCAATAGGGGCCTATCTTAATGCACTTGTTTGGACACATTTCTGATCTTATTTGTAAAGGCTGCAAAAGGAGAGGATGAAATGCTGTAAA
AGTAGGAAATGAAGTGGAAGCTGGAAGAAAATGTAATTGGTGGTACAGCTATGGGCCAGATGGTGGAGGGGAGGGTGGGGACCCCTGCCG
GCAAGCAGAGTGTCACAGCTGGCTTTCCTCACTTGGGAAAAGGGTACTGCCGGTCTAGCAGCCTCCTCTGTACTCAGCCAGGACACCCAG
CGCGTGGGACCTGTTTGTGTCTGTTTTGCTTCCTTGGGAACGGCACAGTCACTCACCCTGCCATTTGCGGAAATGACCTGGTGCACTTTG
ACTGTTAAGCAATGCGTTATTGCTGTAGTCAAGGTTAGTGCAAGCAAGGAAACATTCCCAGTAAGGTATTTGTTTCCATTTTCTGTCTGT

>65519_65519_4_PIP5K1B-PGM5_PIP5K1B_chr9_71555706_ENST00000541509_PGM5_chr9_71080009_ENST00000396396_length(amino acids)=720AA_BP=500
MSSAAENGEAAPGKQNEEKTYKKTASSAIKGAIQLGIGYTVGNLTSKPERDVLMQDFYVVESVFLPSEGSNLTPAHHYPDFRFKTYAPLA
FRYFRELFGIKPDDYLYSICSEPLIELSNPGASGSLFFVTSDDEFIIKTVQHKEAEFLQKLLPGYYMNLNQNPRTLLPKFYGLYCMQSGG
INIRIVVMNNVLPRSMRMHFTYDLKGSTYKRRASRKEREKSNPTFKDLDFLQDMHEGLYFDTETYNALMKTLQRDCRVLESFKIMDYSLL
LGIHFLDHSLKEKEEETPQNVPDAKRTGMQKVLYSTAMESIQGPGKSGDGIITENPDTMGGIPAKSHRGEKLLLFMGIIDILQSYRLMKK
LEHSWKALVYDGDTVSVHRPSFYADRFLKFMNSRVFKKIQALKASPSKKRCNSIAALKATSQEIVSSISQEWKDEKRDLLTEGQSFSSLD
EEALGSRHRPDLVPSTPSLFEAASLATTISSSSLYVNEHYPHDRPTLYSNRVAKSMKVPVYETPAGWRFFSNLMDSGRCNLCGEESFGTG
SDHLREKDGLWAVLVWLSIIAARKQSVEEIVRDHWAKFGRHYYCRFDYEGLDPKTTYYIMRDLEALVTDKSFIGQQFAVGSHVYSVAKTD
SFEYVDPVDGTVTKKQGLRIIFSDASRLIFRLSSSSGVRATLRLYAESYERDPSGHDQEPQAVLSPLIAIALKISQIHERTGRRGPTVIT

--------------------------------------------------------------

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Fusion Gene PPI Analysis for PIP5K1B-PGM5


check button Go to ChiPPI (Chimeric Protein-Protein interactions) to see the chimeric PPI interaction in

ChiPPI page.


check button Protein-protein interactors with each fusion partner protein in wild-type (BIOGRID-3.4.160)
HgeneHgene's interactorsTgeneTgene's interactors


check button - Retained PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenStill interaction with


check button - Lost PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


check button - Retained PPIs, but lost function due to frame-shift fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


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Related Drugs for PIP5K1B-PGM5


check button Drugs targeting genes involved in this fusion gene.
(DrugBank Version 5.1.8 2021-05-08)
PartnerGeneUniProtAccDrugBank IDDrug nameDrug activityDrug typeDrug status

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Related Diseases for PIP5K1B-PGM5


check button Diseases associated with fusion partners.
(DisGeNet 4.0)
PartnerGeneDisease IDDisease name# pubmedsSource