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Center for Computational Systems Medicine
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Fusion Gene Summary

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Fusion Gene ORF analysis

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Fusion Genomic Features

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Fusion Protein Features

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Fusion Gene Sequence

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Fusion Gene PPI analysis

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Related Drugs

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Related Diseases

Fusion gene:PISD-EIF4ENIF1 (FusionGDB2 ID:65544)

Fusion Gene Summary for PISD-EIF4ENIF1

check button Fusion gene summary
Fusion gene informationFusion gene name: PISD-EIF4ENIF1
Fusion gene ID: 65544
HgeneTgene
Gene symbol

PISD

EIF4ENIF1

Gene ID

23761

56478

Gene namephosphatidylserine decarboxylaseeukaryotic translation initiation factor 4E nuclear import factor 1
SynonymsDJ858B16|PSD|PSDC|PSSC|dJ858B16.24E-T|Clast4
Cytomap

22q12.2

22q12.2

Type of geneprotein-codingprotein-coding
Descriptionphosphatidylserine decarboxylase proenzyme, mitochondrialeukaryotic translation initiation factor 4E transporter2610509L04Rik4E-transportereIF4E transporter
Modification date2020032920200327
UniProtAcc.

Q9NRA8

Ensembl transtripts involved in fusion geneENST00000336566, ENST00000439502, 
ENST00000266095, ENST00000382151, 
ENST00000397500, ENST00000478893, 
ENST00000382180, ENST00000441289, 
ENST00000330125, ENST00000344710, 
ENST00000397523, ENST00000397525, 
Fusion gene scores* DoF score7 X 9 X 5=31510 X 7 X 9=630
# samples 911
** MAII scorelog2(9/315*10)=-1.8073549220576
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0		log2(11/630*10)=-2.51784830486262
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0
Context

PubMed: PISD [Title/Abstract] AND EIF4ENIF1 [Title/Abstract] AND fusion [Title/Abstract]

Most frequent breakpointPISD(32044087)-EIF4ENIF1(31867903), # samples:1
Anticipated loss of major functional domain due to fusion event.
* DoF score (Degree of Frequency) = # partners X # break points X # cancer types
** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10)

check button Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez
PartnerGeneGO IDGO termPubMed ID

check buttonFusion gene breakpoints across PISD (5'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.
all structure

check buttonFusion gene breakpoints across EIF4ENIF1 (3'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.
all structure

check button Fusion gene information from two resources (ChiTars 5.0 and ChimerDB 4.0)
* All genome coordinats were lifted-over on hg19.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
SourceDiseaseSampleHgeneHchrHbpHstrandTgeneTchrTbpTstrand
ChimerDB4STADTCGA-VQ-A8P3-01APISDchr22

32044087

-EIF4ENIF1chr22

31867903

-


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Fusion Gene ORF analysis for PISD-EIF4ENIF1

check button Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
ORFHenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrand
5CDS-intronENST00000336566ENST00000382180PISDchr22

32044087

-EIF4ENIF1chr22

31867903

-
5CDS-intronENST00000336566ENST00000441289PISDchr22

32044087

-EIF4ENIF1chr22

31867903

-
5CDS-intronENST00000439502ENST00000382180PISDchr22

32044087

-EIF4ENIF1chr22

31867903

-
5CDS-intronENST00000439502ENST00000441289PISDchr22

32044087

-EIF4ENIF1chr22

31867903

-
In-frameENST00000336566ENST00000330125PISDchr22

32044087

-EIF4ENIF1chr22

31867903

-
In-frameENST00000336566ENST00000344710PISDchr22

32044087

-EIF4ENIF1chr22

31867903

-
In-frameENST00000336566ENST00000397523PISDchr22

32044087

-EIF4ENIF1chr22

31867903

-
In-frameENST00000336566ENST00000397525PISDchr22

32044087

-EIF4ENIF1chr22

31867903

-
In-frameENST00000439502ENST00000330125PISDchr22

32044087

-EIF4ENIF1chr22

31867903

-
In-frameENST00000439502ENST00000344710PISDchr22

32044087

-EIF4ENIF1chr22

31867903

-
In-frameENST00000439502ENST00000397523PISDchr22

32044087

-EIF4ENIF1chr22

31867903

-
In-frameENST00000439502ENST00000397525PISDchr22

32044087

-EIF4ENIF1chr22

31867903

-
intron-3CDSENST00000266095ENST00000330125PISDchr22

32044087

-EIF4ENIF1chr22

31867903

-
intron-3CDSENST00000266095ENST00000344710PISDchr22

32044087

-EIF4ENIF1chr22

31867903

-
intron-3CDSENST00000266095ENST00000397523PISDchr22

32044087

-EIF4ENIF1chr22

31867903

-
intron-3CDSENST00000266095ENST00000397525PISDchr22

32044087

-EIF4ENIF1chr22

31867903

-
intron-3CDSENST00000382151ENST00000330125PISDchr22

32044087

-EIF4ENIF1chr22

31867903

-
intron-3CDSENST00000382151ENST00000344710PISDchr22

32044087

-EIF4ENIF1chr22

31867903

-
intron-3CDSENST00000382151ENST00000397523PISDchr22

32044087

-EIF4ENIF1chr22

31867903

-
intron-3CDSENST00000382151ENST00000397525PISDchr22

32044087

-EIF4ENIF1chr22

31867903

-
intron-3CDSENST00000397500ENST00000330125PISDchr22

32044087

-EIF4ENIF1chr22

31867903

-
intron-3CDSENST00000397500ENST00000344710PISDchr22

32044087

-EIF4ENIF1chr22

31867903

-
intron-3CDSENST00000397500ENST00000397523PISDchr22

32044087

-EIF4ENIF1chr22

31867903

-
intron-3CDSENST00000397500ENST00000397525PISDchr22

32044087

-EIF4ENIF1chr22

31867903

-
intron-3CDSENST00000478893ENST00000330125PISDchr22

32044087

-EIF4ENIF1chr22

31867903

-
intron-3CDSENST00000478893ENST00000344710PISDchr22

32044087

-EIF4ENIF1chr22

31867903

-
intron-3CDSENST00000478893ENST00000397523PISDchr22

32044087

-EIF4ENIF1chr22

31867903

-
intron-3CDSENST00000478893ENST00000397525PISDchr22

32044087

-EIF4ENIF1chr22

31867903

-
intron-intronENST00000266095ENST00000382180PISDchr22

32044087

-EIF4ENIF1chr22

31867903

-
intron-intronENST00000266095ENST00000441289PISDchr22

32044087

-EIF4ENIF1chr22

31867903

-
intron-intronENST00000382151ENST00000382180PISDchr22

32044087

-EIF4ENIF1chr22

31867903

-
intron-intronENST00000382151ENST00000441289PISDchr22

32044087

-EIF4ENIF1chr22

31867903

-
intron-intronENST00000397500ENST00000382180PISDchr22

32044087

-EIF4ENIF1chr22

31867903

-
intron-intronENST00000397500ENST00000441289PISDchr22

32044087

-EIF4ENIF1chr22

31867903

-
intron-intronENST00000478893ENST00000382180PISDchr22

32044087

-EIF4ENIF1chr22

31867903

-
intron-intronENST00000478893ENST00000441289PISDchr22

32044087

-EIF4ENIF1chr22

31867903

-

check buttonORFfinder result based on the fusion transcript sequence of in-frame fusion genes.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandSeq length
(transcript)		BP loci
(transcript)		Predicted start
(transcript)		Predicted stop
(transcript)		Seq length
(amino acids)
ENST00000336566PISDchr2232044087-ENST00000344710EIF4ENIF1chr2231867903-317832102660886
ENST00000336566PISDchr2232044087-ENST00000397525EIF4ENIF1chr2231867903-3696321031821060
ENST00000336566PISDchr2232044087-ENST00000330125EIF4ENIF1chr2231867903-3694321031821060
ENST00000336566PISDchr2232044087-ENST00000397523EIF4ENIF1chr2231867903-3618321031101036
ENST00000439502PISDchr2232044087-ENST00000344710EIF4ENIF1chr2231867903-34025452242884886
ENST00000439502PISDchr2232044087-ENST00000397525EIF4ENIF1chr2231867903-392054522434061060
ENST00000439502PISDchr2232044087-ENST00000330125EIF4ENIF1chr2231867903-391854522434061060
ENST00000439502PISDchr2232044087-ENST00000397523EIF4ENIF1chr2231867903-384254522433341036

check buttonDeepORF prediction of the coding potential based on the fusion transcript sequence of in-frame fusion genes. DeepORF is a coding potential classifier based on convolutional neural network by comparing the real Ribo-seq data. If the no-coding score < 0.5 and coding score > 0.5, then the in-frame fusion transcript is predicted as being likely translated.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandNo-coding scoreCoding score
ENST00000336566ENST00000344710PISDchr2232044087-EIF4ENIF1chr2231867903-0.0015122170.9984877
ENST00000336566ENST00000397525PISDchr2232044087-EIF4ENIF1chr2231867903-0.0003493350.9996507
ENST00000336566ENST00000330125PISDchr2232044087-EIF4ENIF1chr2231867903-0.0003443440.9996556
ENST00000336566ENST00000397523PISDchr2232044087-EIF4ENIF1chr2231867903-0.0009870120.99901295
ENST00000439502ENST00000344710PISDchr2232044087-EIF4ENIF1chr2231867903-0.0016227850.9983772
ENST00000439502ENST00000397525PISDchr2232044087-EIF4ENIF1chr2231867903-0.0004866440.9995134
ENST00000439502ENST00000330125PISDchr2232044087-EIF4ENIF1chr2231867903-0.0004802410.9995198
ENST00000439502ENST00000397523PISDchr2232044087-EIF4ENIF1chr2231867903-0.0013408960.99865913

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Fusion Genomic Features for PISD-EIF4ENIF1


check buttonFusionAI prediction of the potential fusion gene breakpoint based on the pre-mature RNA sequence context (+/- 5kb of individual partner genes, total 20kb length sequence). FusionAI is a fusion gene breakpoint classifier based on convolutional neural network by comparing the fusion positive and negative sequence context of ~ 20K fusion gene data. From here, we can have the relative potentency of the 20K genomic sequence how individual sequnce will be likely used as the gene fusion breakpoints.
HgeneHchrHbpHstrandTgeneTchrTbpTstrand1-pp (fusion gene breakpoint)

check buttonDistribution of 44 human genomic features loci across 20kb length fusion breakpoint regions. We integrated a total of 44 different types of human genomic feature loci information across five big categories including virus integration sites, repeats, structural variants, chromatin states, and gene expression regulation. More details are in help page.
genomic feature

check buttonDistribution of 44 human genomic features loci across 20kb length fusion breakpoint regions that are ovelapped with the top 1% feature importance score regions. More details are in help page.

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Fusion Protein Features for PISD-EIF4ENIF1


check button Four levels of functional features of fusion genes
Go to FGviewer search page for the most frequent breakpoint (https://ccsmweb.uth.edu/FGviewer/chr22:32044087/chr22:31867903)
- FGviewer provides the online visualization of the retention search of the protein functional features across DNA, RNA, protein, and pathological levels.
- How to search
1. Put your fusion gene symbol.
2. Press the tab key until there will be shown the breakpoint information filled.
4. Go down and press 'Search' tab twice.
4. Go down to have the hyperlink of the search result.
5. Click the hyperlink.
6. See the FGviewer result for your fusion gene.
FGviewer

check buttonMain function of each fusion partner protein. (from UniProt)
HgeneTgene
.EIF4ENIF1

Q9NRA8

FUNCTION: Transcriptional activator which is required for calcium-dependent dendritic growth and branching in cortical neurons. Recruits CREB-binding protein (CREBBP) to nuclear bodies. Component of the CREST-BRG1 complex, a multiprotein complex that regulates promoter activation by orchestrating a calcium-dependent release of a repressor complex and a recruitment of an activator complex. In resting neurons, transcription of the c-FOS promoter is inhibited by BRG1-dependent recruitment of a phospho-RB1-HDAC1 repressor complex. Upon calcium influx, RB1 is dephosphorylated by calcineurin, which leads to release of the repressor complex. At the same time, there is increased recruitment of CREBBP to the promoter by a CREST-dependent mechanism, which leads to transcriptional activation. The CREST-BRG1 complex also binds to the NR2B promoter, and activity-dependent induction of NR2B expression involves a release of HDAC1 and recruitment of CREBBP (By similarity). {ECO:0000250}.FUNCTION: EIF4E-binding protein that regulates translation and stability of mRNAs in processing bodies (P-bodies) (PubMed:16157702, PubMed:24335285, PubMed:27342281, PubMed:32354837). Plays a key role in P-bodies to coordinate the storage of translationally inactive mRNAs in the cytoplasm and prevent their degradation (PubMed:24335285, PubMed:32354837). Acts as a binding platform for multiple RNA-binding proteins: promotes deadenylation of mRNAs via its interaction with the CCR4-NOT complex, and blocks decapping via interaction with eIF4E (EIF4E and EIF4E2), thereby protecting deadenylated and repressed mRNAs from degradation (PubMed:27342281, PubMed:32354837). Component of a multiprotein complex that sequesters and represses translation of proneurogenic factors during neurogenesis (By similarity). Promotes miRNA-mediated translational repression (PubMed:24335285, PubMed:27342281, PubMed:28487484). Required for the formation of P-bodies (PubMed:16157702, PubMed:22966201, PubMed:27342281, PubMed:32354837). Involved in mRNA translational repression mediated by the miRNA effector TNRC6B by protecting TNRC6B-targeted mRNAs from decapping and subsequent decay (PubMed:32354837). Also acts as a nucleoplasmic shuttling protein, which mediates the nuclear import of EIF4E and DDX6 by a piggy-back mechanism (PubMed:10856257, PubMed:28216671). {ECO:0000250|UniProtKB:Q9EST3, ECO:0000269|PubMed:10856257, ECO:0000269|PubMed:16157702, ECO:0000269|PubMed:22966201, ECO:0000269|PubMed:24335285, ECO:0000269|PubMed:27342281, ECO:0000269|PubMed:28216671, ECO:0000269|PubMed:28487484, ECO:0000269|PubMed:32354837}.

check buttonRetention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at

download page


* Minus value of BPloci means that the break pointn is located before the CDS.
- In-frame and retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
HgenePISDchr22:32044087chr22:31867903ENST00000336566-3853_63107409.0Topological domainMitochondrial matrix
HgenePISDchr22:32044087chr22:31867903ENST00000439502-3853_63107410.0Topological domainMitochondrial matrix
HgenePISDchr22:32044087chr22:31867903ENST00000336566-3864_82107409.0TransmembraneHelical
HgenePISDchr22:32044087chr22:31867903ENST00000439502-3864_82107410.0TransmembraneHelical
TgeneEIF4ENIF1chr22:32044087chr22:31867903ENST00000330125119148_21032986.0Compositional biasNote=Arg-rich
TgeneEIF4ENIF1chr22:32044087chr22:31867903ENST00000344710117148_21032812.0Compositional biasNote=Arg-rich
TgeneEIF4ENIF1chr22:32044087chr22:31867903ENST00000397525119148_21032986.0Compositional biasNote=Arg-rich
TgeneEIF4ENIF1chr22:32044087chr22:31867903ENST00000330125119195_21132986.0MotifNuclear localization signal
TgeneEIF4ENIF1chr22:32044087chr22:31867903ENST00000330125119438_44732986.0MotifNuclear export signal
TgeneEIF4ENIF1chr22:32044087chr22:31867903ENST00000330125119613_63832986.0MotifNuclear export signal
TgeneEIF4ENIF1chr22:32044087chr22:31867903ENST00000344710117195_21132812.0MotifNuclear localization signal
TgeneEIF4ENIF1chr22:32044087chr22:31867903ENST00000344710117438_44732812.0MotifNuclear export signal
TgeneEIF4ENIF1chr22:32044087chr22:31867903ENST00000344710117613_63832812.0MotifNuclear export signal
TgeneEIF4ENIF1chr22:32044087chr22:31867903ENST00000397525119195_21132986.0MotifNuclear localization signal
TgeneEIF4ENIF1chr22:32044087chr22:31867903ENST00000397525119438_44732986.0MotifNuclear export signal
TgeneEIF4ENIF1chr22:32044087chr22:31867903ENST00000397525119613_63832986.0MotifNuclear export signal
TgeneEIF4ENIF1chr22:32044087chr22:31867903ENST00000330125119664_69332986.0RegionDisordered
TgeneEIF4ENIF1chr22:32044087chr22:31867903ENST00000330125119707_80332986.0RegionDisordered
TgeneEIF4ENIF1chr22:32044087chr22:31867903ENST00000330125119922_95332986.0RegionDisordered
TgeneEIF4ENIF1chr22:32044087chr22:31867903ENST00000344710117664_69332812.0RegionDisordered
TgeneEIF4ENIF1chr22:32044087chr22:31867903ENST00000344710117707_80332812.0RegionDisordered
TgeneEIF4ENIF1chr22:32044087chr22:31867903ENST00000344710117922_95332812.0RegionDisordered
TgeneEIF4ENIF1chr22:32044087chr22:31867903ENST00000397525119664_69332986.0RegionDisordered
TgeneEIF4ENIF1chr22:32044087chr22:31867903ENST00000397525119707_80332986.0RegionDisordered
TgeneEIF4ENIF1chr22:32044087chr22:31867903ENST00000397525119922_95332986.0RegionDisordered

- In-frame and not-retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
HgenePISDchr22:32044087chr22:31867903ENST00000266095-1953_630376.0Topological domainMitochondrial matrix
HgenePISDchr22:32044087chr22:31867903ENST00000266095-1983_4090376.0Topological domainMitochondrial intermembrane
HgenePISDchr22:32044087chr22:31867903ENST00000336566-3883_409107409.0Topological domainMitochondrial intermembrane
HgenePISDchr22:32044087chr22:31867903ENST00000382151-1853_630376.0Topological domainMitochondrial matrix
HgenePISDchr22:32044087chr22:31867903ENST00000382151-1883_4090376.0Topological domainMitochondrial intermembrane
HgenePISDchr22:32044087chr22:31867903ENST00000439502-3883_409107410.0Topological domainMitochondrial intermembrane
HgenePISDchr22:32044087chr22:31867903ENST00000266095-1964_820376.0TransmembraneHelical
HgenePISDchr22:32044087chr22:31867903ENST00000382151-1864_820376.0TransmembraneHelical
TgeneEIF4ENIF1chr22:32044087chr22:31867903ENST000003301251191_2432986.0RegionDisordered
TgeneEIF4ENIF1chr22:32044087chr22:31867903ENST000003447101171_2432812.0RegionDisordered
TgeneEIF4ENIF1chr22:32044087chr22:31867903ENST000003975251191_2432986.0RegionDisordered


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Fusion Gene Sequence for PISD-EIF4ENIF1


check button For in-frame fusion transcripts, we provide the fusion transcript sequences and fusion amino acid sequences. To have fusion amino acid sequence, we ran ORFfinder and chose the longest ORF among the all predicted ones.
>65544_65544_1_PISD-EIF4ENIF1_PISD_chr22_32044087_ENST00000336566_EIF4ENIF1_chr22_31867903_ENST00000330125_length(transcript)=3694nt_BP=321nt
ATGGCGACGTCCGTGGGGCACCGATGTCTGGGATTACTGCACGGGGTCGCGCCGTGGCGGAGCAGCCTCCATCCCTGTGAGATCACTGCC
CTGAGCCAATCCCTACAGCCCTTACGGAAGCTGCCTTTTAGAGCCTTTCGCACAGATGCCAGAAAAATCCACACTGCCCCTGCCCGAACC
ATGTTCCTGCTGCGTCCCCTGCCCATTCTGTTGGTGACAGGCGGCGGGTATGCAGGGTACCGGCAGTATGAGAAGTACAGGGAGCGAGAG
CTGGAGAAGCTGGGATTGGAGATTCCACCCAAACTTGCTGGTCACTGGGAGGAAGAACTCTTGGATATAAAAGAACTCCCCCATTCCAAA
CAGAGGCCTTCATGCCTTTCTGAAAAATATGACAGTGATGGTGTCTGGGACCCTGAGAAGTGGCATGCCTCTCTCTACCCAGCTTCAGGG
CGGAGCTCACCAGTGGAAAGTCTGAAGAAAGAGTTGGATACAGACCGGCCTTCCCTGGTGCGCAGGATAGTAGATCCACGAGAGCGTGTG
AAAGAAGATGACTTAGATGTTGTTCTCAGCCCTCAGAGACGGAGCTTTGGAGGGGGCTGCCACGTGACAGCCGCTGTTAGCTCCCGGCGC
TCAGGAAGTCCATTAGAGAAAGATAGTGATGGGCTTCGTCTGCTTGGTGGACGTAGGATTGGCAGTGGGAGGATAATCTCTGCCCGGACC
TTTGAGAAGGATCACCGTCTTAGCGATAAGGACCTGCGGGACTTGAGAGACAGAGACCGAGAGAGGGACTTCAAGGACAAGCGTTTCAGG
AGAGAGTTTGGAGATAGTAAGCGTGTCTTTGGTGAGCGTAGAAGAAATGATTCTTACACAGAAGAAGAACCAGAGTGGTTCTCTGCTGGA
CCCACAAGTCAGTCTGAAACCATCGAACTGACTGGCTTTGATGATAAGATACTAGAAGAAGATCACAAAGGGAGAAAAAGAACAAGGCGA
CGGACAGCCTCTGTGAAGGAAGGTATAGTAGAGTGCAATGGAGGAGTGGCCGAAGAGGATGAAGTGGAGGTCATCCTTGCACAGGAGCCT
GCGGCTGATCAGGAAGTGCCAAGGGATGCTGTCTTGCCTGAGCAGTCCCCAGGAGACTTTGACTTTAATGAGTTCTTTAACCTTGATAAG
GTGCCATGCTTGGCTTCGATGATAGAAGATGTTTTGGGAGAAGGGTCAGTCTCTGCCAGTCGGTTCAGTAGGTGGTTCTCTAACCCGAGC
AGATCAGGAAGCCGATCCAGCAGTCTTGGGTCAACACCACATGAAGAGCTAGAGAGACTTGCAGGTCTGGAGCAAGCCATCCTCTCTCCT
GGACAGAACTCGGGGAATTACTTTGCTCCTATACCATTGGAAGACCATGCTGAAAATAAAGTGGATATTTTAGAAATGCTACAGAAAGCC
AAAGTGGATTTGAAACCTCTTCTTTCCAGCCTTTCTGCAAATAAAGAAAAACTTAAAGAAAGCTCACATTCAGGGGTTGTGCTTTCAGTG
GAGGAGGTAGAAGCAGGTCTGAAGGGCTTGAAGGTTGACCAGCAAGTGAAGAATTCAACTCCCTTCATGGCAGAACACCTAGAAGAGACC
TTGAGTGCCGTAACCAACAATCGACAACTGAAGAAAGACGGAGACATGACTGCGTTCAACAAGCTAGTGAGCACAATGAAGGCAAGTGGG
ACTTTGCCTTCTCAGCCCAAAGTCAGCCGAAACCTTGAAAGCCATTTGATGTCCCCTGCTGAGATTCCAGGCCAGCCTGTCCCTAAGAAC
ATCCTGCAGGAACTTCTGGGTCAACCAGTTCAGAGACCTGCTTCTTCCAATCTTCTGAGTGGCCTTATGGGGAGCTTGGAGCCTACAACA
TCTTTACTGGGCCAAAGAGCACCCTCTCCTCCCTTGTCACAGGTGTTTCAAACTCGAGCAGCCTCAGCTGACTACCTTCGCCCAAGAATA
CCATCACCAATTGGTTTCACACCAGGACCACAGCAGCTACTCGGAGATCCATTCCAAGGCATGCGCAAACCCATGAGCCCCATCACAGCC
CAGATGAGCCAGCTGGAGTTGCAACAGGCAGCTTTAGAAGGGCTGGCCTTGCCACATGACCTTGCTGTACAGGCAGCAAACTTCTACCAG
CCTGGTTTTGGCAAACCACAGGTGGACAGAACCAGAGATGGATTCAGAAACAGGCAACAGCGAGTGACCAAGTCACCAGCACCCGTGCAT
CGAGGGAATTCCTCTTCCCCTGCCCCTGCTGCCTCCATCACAAGCATGCTTTCTCCTTCCTTTACCCCTACCTCAGTGATTCGTAAGATG
TACGAGAGCAAAGAGAAAAGCAAGGAGGAGCCAGCATCTGGAAAAGCAGCTCTTGGTGACAGTAAAGAGGATACTCAGAAGGCCAGTGAA
GAAAACCTCCTGTCATCCAGCTCTGTACCCAGTGCCGATCGAGACTCTTCTCCCACTACAAATTCCAAACTGTCAGCATTACAGAGGTCT
TCGTGTTCCACCCCACTGTCCCAGGCCAACCGTTACACCAAAGAACAAGATTATCGACCTAAAGCAACTGGGAGAAAAACACCCACCTTG
GCATCCCCAGTTCCTACAACACCTTTTCTCCGCCCTGTCCACCAAGTTCCCCTTGTCCCCCATGTCCCTATGGTTAGGCCTGCTCACCAG
CTTCACCCAGGGTTGGTACAGAGGATGCTGGCCCAGGGAGTACATCCACAGCATCTTCCAAGTTTGCTCCAAACTGGTGTGCTTCCTCCT
GGGATGGACTTGAGTCATTTACAGGGAATATCTGGCCCCATCCTGGGTCAGCCCTTTTACCCTTTACCTGCTGCTAGTCACCCTCTCTTA
AACCCTCGTCCTGGAACACCTCTGCATCTGGCAATGGTGCAACAGCAGCTACAGCGCTCAGTTCTGCATCCTCCAGGCTCTGGTTCCCAT
GCAGCAGCTGTCAGCGTTCAGACAACCCCTCAGAACGTGCCCAGCCGGTCAGGCCTGCCCCACATGCACTCCCAGCTGGAGCATCGCCCC
AGCCAGAGGAGCAGCTCCCCTGTGGGCCTTGCCAAATGGTTTGGCTCAGATGTGCTACAGCAACCCCTGCCCTCCATGCCCGCCAAAGTT
ATCAGTGTAGATGAATTGGAATACCGACAGTGAGCAGGGCAGGCAGACTCAACTAAGCCCGGACCTGTGGTGGCACACTGGGCAGGACCC
TGCTTCATCTCGGGTTGGTTTATGGGCTTTTACTTTGGAGCACTCTGTGTGAAGCTGTTTGGTGGAACCCATGCATCTGGTGTGGTCCGC
ATTATGATGGAAGGATCTTAACCAGTCGAGTGGAGTGTACATTGTCTGAATACAGGATGCACAATGTTGTCAATCCTGGAAATGGTCTTT
CTTTTTTGTAAGATATGTGAATGAAGTGTTGGTGTCCTCACCAAGAGGTGGCACCTAAGGGTTCTGAGGAAATAAATGTATAGACCCTTA
TGTACAGACCTGTGTATAAACAACTTTTGTATATACATATAGGATAGCTTTTTTGAACTATACAGCTGTACATAAAAGTAGCTGATATTA
GTTAGGCCTGTGTCAACAGTTTGGATTTTTTTCACTTGTACATTTGGGATTTTCTTTTGGTTGATTAAAATTGCATATGCTAAGTGTGTG

>65544_65544_1_PISD-EIF4ENIF1_PISD_chr22_32044087_ENST00000336566_EIF4ENIF1_chr22_31867903_ENST00000330125_length(amino acids)=1060AA_BP=0
MATSVGHRCLGLLHGVAPWRSSLHPCEITALSQSLQPLRKLPFRAFRTDARKIHTAPARTMFLLRPLPILLVTGGGYAGYRQYEKYRERE
LEKLGLEIPPKLAGHWEEELLDIKELPHSKQRPSCLSEKYDSDGVWDPEKWHASLYPASGRSSPVESLKKELDTDRPSLVRRIVDPRERV
KEDDLDVVLSPQRRSFGGGCHVTAAVSSRRSGSPLEKDSDGLRLLGGRRIGSGRIISARTFEKDHRLSDKDLRDLRDRDRERDFKDKRFR
REFGDSKRVFGERRRNDSYTEEEPEWFSAGPTSQSETIELTGFDDKILEEDHKGRKRTRRRTASVKEGIVECNGGVAEEDEVEVILAQEP
AADQEVPRDAVLPEQSPGDFDFNEFFNLDKVPCLASMIEDVLGEGSVSASRFSRWFSNPSRSGSRSSSLGSTPHEELERLAGLEQAILSP
GQNSGNYFAPIPLEDHAENKVDILEMLQKAKVDLKPLLSSLSANKEKLKESSHSGVVLSVEEVEAGLKGLKVDQQVKNSTPFMAEHLEET
LSAVTNNRQLKKDGDMTAFNKLVSTMKASGTLPSQPKVSRNLESHLMSPAEIPGQPVPKNILQELLGQPVQRPASSNLLSGLMGSLEPTT
SLLGQRAPSPPLSQVFQTRAASADYLRPRIPSPIGFTPGPQQLLGDPFQGMRKPMSPITAQMSQLELQQAALEGLALPHDLAVQAANFYQ
PGFGKPQVDRTRDGFRNRQQRVTKSPAPVHRGNSSSPAPAASITSMLSPSFTPTSVIRKMYESKEKSKEEPASGKAALGDSKEDTQKASE
ENLLSSSSVPSADRDSSPTTNSKLSALQRSSCSTPLSQANRYTKEQDYRPKATGRKTPTLASPVPTTPFLRPVHQVPLVPHVPMVRPAHQ
LHPGLVQRMLAQGVHPQHLPSLLQTGVLPPGMDLSHLQGISGPILGQPFYPLPAASHPLLNPRPGTPLHLAMVQQQLQRSVLHPPGSGSH

--------------------------------------------------------------
>65544_65544_2_PISD-EIF4ENIF1_PISD_chr22_32044087_ENST00000336566_EIF4ENIF1_chr22_31867903_ENST00000344710_length(transcript)=3178nt_BP=321nt
ATGGCGACGTCCGTGGGGCACCGATGTCTGGGATTACTGCACGGGGTCGCGCCGTGGCGGAGCAGCCTCCATCCCTGTGAGATCACTGCC
CTGAGCCAATCCCTACAGCCCTTACGGAAGCTGCCTTTTAGAGCCTTTCGCACAGATGCCAGAAAAATCCACACTGCCCCTGCCCGAACC
ATGTTCCTGCTGCGTCCCCTGCCCATTCTGTTGGTGACAGGCGGCGGGTATGCAGGGTACCGGCAGTATGAGAAGTACAGGGAGCGAGAG
CTGGAGAAGCTGGGATTGGAGATTCCACCCAAACTTGCTGGTCACTGGGAGGAAGAACTCTTGGATATAAAAGAACTCCCCCATTCCAAA
CAGAGGCCTTCATGCCTTTCTGAAAAATATGACAGTGATGGTGTCTGGGACCCTGAGAAGTGGCATGCCTCTCTCTACCCAGCTTCAGGG
CGGAGCTCACCAGTGGAAAGTCTGAAGAAAGAGTTGGATACAGACCGGCCTTCCCTGGTGCGCAGGATAGTAGGTATAGTAGAGTGCAAT
GGAGGAGTGGCCGAAGAGGATGAAGTGGAGGTCATCCTTGCACAGGAGCCTGCGGCTGATCAGGAAGTGCCAAGGGATGCTGTCTTGCCT
GAGCAGTCCCCAGGAGACTTTGACTTTAATGAGTTCTTTAACCTTGATAAGGTGCCATGCTTGGCTTCGATGATAGAAGATGTTTTGGGA
GAAGGGTCAGTCTCTGCCAGTCGGTTCAGTAGGTGGTTCTCTAACCCGAGCAGATCAGGAAGCCGATCCAGCAGTCTTGGGTCAACACCA
CATGAAGAGCTAGAGAGACTTGCAGGTCTGGAGCAAGCCATCCTCTCTCCTGGACAGAACTCGGGGAATTACTTTGCTCCTATACCATTG
GAAGACCATGCTGAAAATAAAGTGGATATTTTAGAAATGCTACAGAAAGCCAAAGTGGATTTGAAACCTCTTCTTTCCAGCCTTTCTGCA
AATAAAGAAAAACTTAAAGAAAGCTCACATTCAGGGGTTGTGCTTTCAGTGGAGGAGGTAGAAGCAGGTCTGAAGGGCTTGAAGGTTGAC
CAGCAAGTGAAGAATTCAACTCCCTTCATGGCAGAACACCTAGAAGAGACCTTGAGTGCCGTAACCAACAATCGACAACTGAAGAAAGAC
GGAGACATGACTGCGTTCAACAAGCTAGTGAGCACAATGAAGCGAAACCTTGAAAGCCATTTGATGTCCCCTGCTGAGATTCCAGGCCAG
CCTGTCCCTAAGAACATCCTGCAGGAACTTCTGGGTCAACCAGTTCAGAGACCTGCTTCTTCCAATCTTCTGAGTGGCCTTATGGGGAGC
TTGGAGCCTACAACATCTTTACTGGGCCAAAGAGCACCCTCTCCTCCCTTGTCACAGGTGTTTCAAACTCGAGCAGCCTCAGCTGACTAC
CTTCGCCCAAGAATACCATCACCAATTGGTTTCACACCAGGACCACAGCAGCTACTCGGAGATCCATTCCAAGGCATGCGCAAACCCATG
AGCCCCATCACAGCCCAGCAGATGAGCCAGCTGGAGTTGCAACAGGCAGCTTTAGAAGGGCTGGCCTTGCCACATGACCTTGCTGTACAG
GCAGCAAACTTCTACCAGCCTGGTTTTGGCAAACCACAGGTGGACAGAACCAGAGATGGATTCAGAAACAGGCAACAGCGAGTGACCAAG
TCACCAGCACCCGTGCATCGAGGGAATTCCTCTTCCCCTGCCCCTGCTGCCTCCATCACAAGCATGCTTTCTCCTTCCTTTACCCCTACC
TCAGTGATTCGTAAGATGTACGAGAGCAAAGAGAAAAGCAAGGAGGAGCCAGCATCTGGAAAAGCAGCTCTTGGTGACAGTAAAGAGGAT
ACTCAGAAGGCCAGTGAAGAAAACCTCCTGTCATCCAGCTCTGTACCCAGTGCCGATCGAGACTCTTCTCCCACTACAAATTCCAAACTG
TCAGCATTACAGAGGTCTTCGTGTTCCACCCCACTGTCCCAGGCCAACCGTTACACCAAAGAACAAGATTATCGACCTAAAGCAACTGGG
AGAAAAACACCCACCTTGGCATCCCCAGTTCCTACAACACCTTTTCTCCGCCCTGTCCACCAAGTTCCCCTTGTCCCCCATGTCCCTATG
GTTAGGCCTGCTCACCAGCTTCACCCAGGGTTGGTACAGAGGATGCTGGCCCAGGGAGTACATCCACAGCATCTTCCAAGTTTGCTCCAA
ACTGGTGTGCTTCCTCCTGGGATGGACTTGAGTCATTTACAGGGAATATCTGGCCCCATCCTGGGTCAGCCCTTTTACCCTTTACCTGCT
GCTAGTCACCCTCTCTTAAACCCTCGTCCTGGAACACCTCTGCATCTGGCAATGGTGCAACAGCAGCTACAGCGCTCAGTTCTGCATCCT
CCAGGCTCTGGTTCCCATGCAGCAGCTGTCAGCGTTCAGACAACCCCTCAGAACGTGCCCAGCCGGTCAGGCCTGCCCCACATGCACTCC
CAGCTGGAGCATCGCCCCAGCCAGAGGAGCAGCTCCCCTGTGGGCCTTGCCAAATGGTTTGGCTCAGATGTGCTACAGCAACCCCTGCCC
TCCATGCCCGCCAAAGTTATCAGTGTAGATGAATTGGAATACCGACAGTGAGCAGGGCAGGCAGACTCAACTAAGCCCGGACCTGTGGTG
GCACACTGGGCAGGACCCTGCTTCATCTCGGGTTGGTTTATGGGCTTTTACTTTGGAGCACTCTGTGTGAAGCTGTTTGGTGGAACCCAT
GCATCTGGTGTGGTCCGCATTATGATGGAAGGATCTTAACCAGTCGAGTGGAGTGTACATTGTCTGAATACAGGATGCACAATGTTGTCA
ATCCTGGAAATGGTCTTTCTTTTTTGTAAGATATGTGAATGAAGTGTTGGTGTCCTCACCAAGAGGTGGCACCTAAGGGTTCTGAGGAAA
TAAATGTATAGACCCTTATGTACAGACCTGTGTATAAACAACTTTTGTATATACATATAGGATAGCTTTTTTGAACTATACAGCTGTACA
TAAAAGTAGCTGATATTAGTTAGGCCTGTGTCAACAGTTTGGATTTTTTTCACTTGTACATTTGGGATTTTCTTTTGGTTGATTAAAATT

>65544_65544_2_PISD-EIF4ENIF1_PISD_chr22_32044087_ENST00000336566_EIF4ENIF1_chr22_31867903_ENST00000344710_length(amino acids)=886AA_BP=0
MATSVGHRCLGLLHGVAPWRSSLHPCEITALSQSLQPLRKLPFRAFRTDARKIHTAPARTMFLLRPLPILLVTGGGYAGYRQYEKYRERE
LEKLGLEIPPKLAGHWEEELLDIKELPHSKQRPSCLSEKYDSDGVWDPEKWHASLYPASGRSSPVESLKKELDTDRPSLVRRIVGIVECN
GGVAEEDEVEVILAQEPAADQEVPRDAVLPEQSPGDFDFNEFFNLDKVPCLASMIEDVLGEGSVSASRFSRWFSNPSRSGSRSSSLGSTP
HEELERLAGLEQAILSPGQNSGNYFAPIPLEDHAENKVDILEMLQKAKVDLKPLLSSLSANKEKLKESSHSGVVLSVEEVEAGLKGLKVD
QQVKNSTPFMAEHLEETLSAVTNNRQLKKDGDMTAFNKLVSTMKRNLESHLMSPAEIPGQPVPKNILQELLGQPVQRPASSNLLSGLMGS
LEPTTSLLGQRAPSPPLSQVFQTRAASADYLRPRIPSPIGFTPGPQQLLGDPFQGMRKPMSPITAQQMSQLELQQAALEGLALPHDLAVQ
AANFYQPGFGKPQVDRTRDGFRNRQQRVTKSPAPVHRGNSSSPAPAASITSMLSPSFTPTSVIRKMYESKEKSKEEPASGKAALGDSKED
TQKASEENLLSSSSVPSADRDSSPTTNSKLSALQRSSCSTPLSQANRYTKEQDYRPKATGRKTPTLASPVPTTPFLRPVHQVPLVPHVPM
VRPAHQLHPGLVQRMLAQGVHPQHLPSLLQTGVLPPGMDLSHLQGISGPILGQPFYPLPAASHPLLNPRPGTPLHLAMVQQQLQRSVLHP

--------------------------------------------------------------
>65544_65544_3_PISD-EIF4ENIF1_PISD_chr22_32044087_ENST00000336566_EIF4ENIF1_chr22_31867903_ENST00000397523_length(transcript)=3618nt_BP=321nt
ATGGCGACGTCCGTGGGGCACCGATGTCTGGGATTACTGCACGGGGTCGCGCCGTGGCGGAGCAGCCTCCATCCCTGTGAGATCACTGCC
CTGAGCCAATCCCTACAGCCCTTACGGAAGCTGCCTTTTAGAGCCTTTCGCACAGATGCCAGAAAAATCCACACTGCCCCTGCCCGAACC
ATGTTCCTGCTGCGTCCCCTGCCCATTCTGTTGGTGACAGGCGGCGGGTATGCAGGGTACCGGCAGTATGAGAAGTACAGGGAGCGAGAG
CTGGAGAAGCTGGGATTGGAGATTCCACCCAAACTTGCTGGTCACTGGGAGGAAGAACTCTTGGATATAAAAGAACTCCCCCATTCCAAA
CAGAGGCCTTCATGCCTTTCTGAAAAATATGACAGTGATGGTGTCTGGGACCCTGAGAAGTGGCATGCCTCTCTCTACCCAGCTTCAGGG
CGGAGCTCACCAGTGGAAAGTCTGAAGAAAGAGTTGGATACAGACCGGCCTTCCCTGGTGCGCAGGATAGTAGATCCACGAGAGCGTGTG
AAAGAAGATGACTTAGATGTTGTTCTCAGCCCTCAGAGACGGAGCTTTGGAGGGGGCTGCCACGTGACAGCCGCTGTTAGCTCCCGGCGC
TCAGGAAGTCCATTAGAGAAAGATAGTGATGGGCTTCGTCTGCTTGGTGGACGTAGGATTGGCAGTGGGAGGATAATCTCTGCCCGGACC
TTTGAGAAGGATCACCGTCTTAGCGATAAGGACCTGCGGGACTTGAGAGACAGAGACCGAGAGAGGGACTTCAAGGACAAGCGTTTCAGG
AGAGAGTTTGGAGATAGTAAGCGTGTCTTTGGTGAGCGTAGAAGAAATGATTCTTACACAGAAGAAGAACCAGAGTGGTTCTCTGCTGGA
CCCACAAGTCAGTCTGAAACCATCGAACTGACTGGCTTTGATGATAAGATACTAGAAGAAGATCACAAAGGGAGAAAAAGAACAAGGCGA
CGGACAGCCTCTGTGAAGGAAGGTATAGTAGAGTGCAATGGAGGAGTGGCCGAAGAGGATGAAGTGGAGGTCATCCTTGCACAGGAGCCT
GCGGCTGATCAGGAAGTGCCAAGGGATGCTGTCTTGCCTGAGCAGTCCCCAGGAGACTTTGACTTTAATGAGTTCTTTAACCTTGATAAG
GTGCCATGCTTGGCTTCGATGATAGAAGATGTTTTGGGAGAAGGGTCAGTCTCTGCCAGTCGGTTCAGTAGGTGGTTCTCTAACCCGAGC
AGATCAGGAAGCCGATCCAGCAGTCTTGGGTCAACACCACATGAAGAGCTAGAGAGACTTGCAGGTCTGGAGCAAGCCATCCTCTCTCCT
GGACAGAACTCGGGGAATTACTTTGCTCCTATACCATTGGAAGACCATGCTGAAAATAAAGTGGATATTTTAGAAATGCTACAGAAAGCC
AAAGTGGATTTGAAACCTCTTCTTTCCAGCCTTTCTGCAAATAAAGAAAAACTTAAAGAAAGCTCACATTCAGGGGTTGTGCTTTCAGTG
GAGGAGGTAGAAGCAGGTCTGAAGGGCTTGAAGGTTGACCAGCAAGTGAAGAATTCAACTCCCTTCATGGCAGAACACCTAGAAGAGACC
TTGAGTGCCGTAACCAACAATCGACAACTGAAGAAAGACGGAGACATGACTGCGTTCAACAAGCTAGTGAGCACAATGAAGGCAAGTGGG
ACTTTGCCTTCTCAGCCCAAAGTCAGCGAACTTCTGGGTCAACCAGTTCAGAGACCTGCTTCTTCCAATCTTCTGAGTGGCCTTATGGGG
AGCTTGGAGCCTACAACATCTTTACTGGGCCAAAGAGCACCCTCTCCTCCCTTGTCACAGGTGTTTCAAACTCGAGCAGCCTCAGCTGAC
TACCTTCGCCCAAGAATACCATCACCAATTGGTTTCACACCAGGACCACAGCAGCTACTCGGAGATCCATTCCAAGGCATGCGCAAACCC
ATGAGCCCCATCACAGCCCAGATGAGCCAGCTGGAGTTGCAACAGGCAGCTTTAGAAGGGCTGGCCTTGCCACATGACCTTGCTGTACAG
GCAGCAAACTTCTACCAGCCTGGTTTTGGCAAACCACAGGTGGACAGAACCAGAGATGGATTCAGAAACAGGCAACAGCGAGTGACCAAG
TCACCAGCACCCGTGCATCGAGGGAATTCCTCTTCCCCTGCCCCTGCTGCCTCCATCACAAGCATGCTTTCTCCTTCCTTTACCCCTACC
TCAGTGATTCGTAAGATGTACGAGAGCAAAGAGAAAAGCAAGGAGGAGCCAGCATCTGGAAAAGCAGCTCTTGGTGACAGTAAAGAGGAT
ACTCAGAAGGCCAGTGAAGAAAACCTCCTGTCATCCAGCTCTGTACCCAGTGCCGATCGAGACTCTTCTCCCACTACAAATTCCAAACTG
TCAGCATTACAGAGGTCTTCGTGTTCCACCCCACTGTCCCAGGCCAACCGTTACACCAAAGAACAAGATTATCGACCTAAAGCAACTGGG
AGAAAAACACCCACCTTGGCATCCCCAGTTCCTACAACACCTTTTCTCCGCCCTGTCCACCAAGTTCCCCTTGTCCCCCATGTCCCTATG
GTTAGGCCTGCTCACCAGCTTCACCCAGGGTTGGTACAGAGGATGCTGGCCCAGGGAGTACATCCACAGCATCTTCCAAGTTTGCTCCAA
ACTGGTGTGCTTCCTCCTGGGATGGACTTGAGTCATTTACAGGGAATATCTGGCCCCATCCTGGGTCAGCCCTTTTACCCTTTACCTGCT
GCTAGTCACCCTCTCTTAAACCCTCGTCCTGGAACACCTCTGCATCTGGCAATGGTGCAACAGCAGCTACAGCGCTCAGTTCTGCATCCT
CCAGGCTCTGGTTCCCATGCAGCAGCTGTCAGCGTTCAGACAACCCCTCAGAACGTGCCCAGCCGGTCAGGCCTGCCCCACATGCACTCC
CAGCTGGAGCATCGCCCCAGCCAGAGGAGCAGCTCCCCTGTGGGCCTTGCCAAATGGTTTGGCTCAGATGTGCTACAGCAACCCCTGCCC
TCCATGCCCGCCAAAGTTATCAGTGTAGATGAATTGGAATACCGACAGTGAGCAGGGCAGGCAGACTCAACTAAGCCCGGACCTGTGGTG
GCACACTGGGCAGGACCCTGCTTCATCTCGGGTTGGTTTATGGGCTTTTACTTTGGAGCACTCTGTGTGAAGCTGTTTGGTGGAACCCAT
GCATCTGGTGTGGTCCGCATTATGATGGAAGGATCTTAACCAGTCGAGTGGAGTGTACATTGTCTGAATACAGGATGCACAATGTTGTCA
ATCCTGGAAATGGTCTTTCTTTTTTGTAAGATATGTGAATGAAGTGTTGGTGTCCTCACCAAGAGGTGGCACCTAAGGGTTCTGAGGAAA
TAAATGTATAGACCCTTATGTACAGACCTGTGTATAAACAACTTTTGTATATACATATAGGATAGCTTTTTTGAACTATACAGCTGTACA
TAAAAGTAGCTGATATTAGTTAGGCCTGTGTCAACAGTTTGGATTTTTTTCACTTGTACATTTGGGATTTTCTTTTGGTTGATTAAAATT

>65544_65544_3_PISD-EIF4ENIF1_PISD_chr22_32044087_ENST00000336566_EIF4ENIF1_chr22_31867903_ENST00000397523_length(amino acids)=1036AA_BP=0
MATSVGHRCLGLLHGVAPWRSSLHPCEITALSQSLQPLRKLPFRAFRTDARKIHTAPARTMFLLRPLPILLVTGGGYAGYRQYEKYRERE
LEKLGLEIPPKLAGHWEEELLDIKELPHSKQRPSCLSEKYDSDGVWDPEKWHASLYPASGRSSPVESLKKELDTDRPSLVRRIVDPRERV
KEDDLDVVLSPQRRSFGGGCHVTAAVSSRRSGSPLEKDSDGLRLLGGRRIGSGRIISARTFEKDHRLSDKDLRDLRDRDRERDFKDKRFR
REFGDSKRVFGERRRNDSYTEEEPEWFSAGPTSQSETIELTGFDDKILEEDHKGRKRTRRRTASVKEGIVECNGGVAEEDEVEVILAQEP
AADQEVPRDAVLPEQSPGDFDFNEFFNLDKVPCLASMIEDVLGEGSVSASRFSRWFSNPSRSGSRSSSLGSTPHEELERLAGLEQAILSP
GQNSGNYFAPIPLEDHAENKVDILEMLQKAKVDLKPLLSSLSANKEKLKESSHSGVVLSVEEVEAGLKGLKVDQQVKNSTPFMAEHLEET
LSAVTNNRQLKKDGDMTAFNKLVSTMKASGTLPSQPKVSELLGQPVQRPASSNLLSGLMGSLEPTTSLLGQRAPSPPLSQVFQTRAASAD
YLRPRIPSPIGFTPGPQQLLGDPFQGMRKPMSPITAQMSQLELQQAALEGLALPHDLAVQAANFYQPGFGKPQVDRTRDGFRNRQQRVTK
SPAPVHRGNSSSPAPAASITSMLSPSFTPTSVIRKMYESKEKSKEEPASGKAALGDSKEDTQKASEENLLSSSSVPSADRDSSPTTNSKL
SALQRSSCSTPLSQANRYTKEQDYRPKATGRKTPTLASPVPTTPFLRPVHQVPLVPHVPMVRPAHQLHPGLVQRMLAQGVHPQHLPSLLQ
TGVLPPGMDLSHLQGISGPILGQPFYPLPAASHPLLNPRPGTPLHLAMVQQQLQRSVLHPPGSGSHAAAVSVQTTPQNVPSRSGLPHMHS

--------------------------------------------------------------
>65544_65544_4_PISD-EIF4ENIF1_PISD_chr22_32044087_ENST00000336566_EIF4ENIF1_chr22_31867903_ENST00000397525_length(transcript)=3696nt_BP=321nt
ATGGCGACGTCCGTGGGGCACCGATGTCTGGGATTACTGCACGGGGTCGCGCCGTGGCGGAGCAGCCTCCATCCCTGTGAGATCACTGCC
CTGAGCCAATCCCTACAGCCCTTACGGAAGCTGCCTTTTAGAGCCTTTCGCACAGATGCCAGAAAAATCCACACTGCCCCTGCCCGAACC
ATGTTCCTGCTGCGTCCCCTGCCCATTCTGTTGGTGACAGGCGGCGGGTATGCAGGGTACCGGCAGTATGAGAAGTACAGGGAGCGAGAG
CTGGAGAAGCTGGGATTGGAGATTCCACCCAAACTTGCTGGTCACTGGGAGGAAGAACTCTTGGATATAAAAGAACTCCCCCATTCCAAA
CAGAGGCCTTCATGCCTTTCTGAAAAATATGACAGTGATGGTGTCTGGGACCCTGAGAAGTGGCATGCCTCTCTCTACCCAGCTTCAGGG
CGGAGCTCACCAGTGGAAAGTCTGAAGAAAGAGTTGGATACAGACCGGCCTTCCCTGGTGCGCAGGATAGTAGATCCACGAGAGCGTGTG
AAAGAAGATGACTTAGATGTTGTTCTCAGCCCTCAGAGACGGAGCTTTGGAGGGGGCTGCCACGTGACAGCCGCTGTTAGCTCCCGGCGC
TCAGGAAGTCCATTAGAGAAAGATAGTGATGGGCTTCGTCTGCTTGGTGGACGTAGGATTGGCAGTGGGAGGATAATCTCTGCCCGGACC
TTTGAGAAGGATCACCGTCTTAGCGATAAGGACCTGCGGGACTTGAGAGACAGAGACCGAGAGAGGGACTTCAAGGACAAGCGTTTCAGG
AGAGAGTTTGGAGATAGTAAGCGTGTCTTTGGTGAGCGTAGAAGAAATGATTCTTACACAGAAGAAGAACCAGAGTGGTTCTCTGCTGGA
CCCACAAGTCAGTCTGAAACCATCGAACTGACTGGCTTTGATGATAAGATACTAGAAGAAGATCACAAAGGGAGAAAAAGAACAAGGCGA
CGGACAGCCTCTGTGAAGGAAGGTATAGTAGAGTGCAATGGAGGAGTGGCCGAAGAGGATGAAGTGGAGGTCATCCTTGCACAGGAGCCT
GCGGCTGATCAGGAAGTGCCAAGGGATGCTGTCTTGCCTGAGCAGTCCCCAGGAGACTTTGACTTTAATGAGTTCTTTAACCTTGATAAG
GTGCCATGCTTGGCTTCGATGATAGAAGATGTTTTGGGAGAAGGGTCAGTCTCTGCCAGTCGGTTCAGTAGGTGGTTCTCTAACCCGAGC
AGATCAGGAAGCCGATCCAGCAGTCTTGGGTCAACACCACATGAAGAGCTAGAGAGACTTGCAGGTCTGGAGCAAGCCATCCTCTCTCCT
GGACAGAACTCGGGGAATTACTTTGCTCCTATACCATTGGAAGACCATGCTGAAAATAAAGTGGATATTTTAGAAATGCTACAGAAAGCC
AAAGTGGATTTGAAACCTCTTCTTTCCAGCCTTTCTGCAAATAAAGAAAAACTTAAAGAAAGCTCACATTCAGGGGTTGTGCTTTCAGTG
GAGGAGGTAGAAGCAGGTCTGAAGGGCTTGAAGGTTGACCAGCAAGTGAAGAATTCAACTCCCTTCATGGCAGAACACCTAGAAGAGACC
TTGAGTGCCGTAACCAACAATCGACAACTGAAGAAAGACGGAGACATGACTGCGTTCAACAAGCTAGTGAGCACAATGAAGGCAAGTGGG
ACTTTGCCTTCTCAGCCCAAAGTCAGCCGAAACCTTGAAAGCCATTTGATGTCCCCTGCTGAGATTCCAGGCCAGCCTGTCCCTAAGAAC
ATCCTGCAGGAACTTCTGGGTCAACCAGTTCAGAGACCTGCTTCTTCCAATCTTCTGAGTGGCCTTATGGGGAGCTTGGAGCCTACAACA
TCTTTACTGGGCCAAAGAGCACCCTCTCCTCCCTTGTCACAGGTGTTTCAAACTCGAGCAGCCTCAGCTGACTACCTTCGCCCAAGAATA
CCATCACCAATTGGTTTCACACCAGGACCACAGCAGCTACTCGGAGATCCATTCCAAGGCATGCGCAAACCCATGAGCCCCATCACAGCC
CAGATGAGCCAGCTGGAGTTGCAACAGGCAGCTTTAGAAGGGCTGGCCTTGCCACATGACCTTGCTGTACAGGCAGCAAACTTCTACCAG
CCTGGTTTTGGCAAACCACAGGTGGACAGAACCAGAGATGGATTCAGAAACAGGCAACAGCGAGTGACCAAGTCACCAGCACCCGTGCAT
CGAGGGAATTCCTCTTCCCCTGCCCCTGCTGCCTCCATCACAAGCATGCTTTCTCCTTCCTTTACCCCTACCTCAGTGATTCGTAAGATG
TACGAGAGCAAAGAGAAAAGCAAGGAGGAGCCAGCATCTGGAAAAGCAGCTCTTGGTGACAGTAAAGAGGATACTCAGAAGGCCAGTGAA
GAAAACCTCCTGTCATCCAGCTCTGTACCCAGTGCCGATCGAGACTCTTCTCCCACTACAAATTCCAAACTGTCAGCATTACAGAGGTCT
TCGTGTTCCACCCCACTGTCCCAGGCCAACCGTTACACCAAAGAACAAGATTATCGACCTAAAGCAACTGGGAGAAAAACACCCACCTTG
GCATCCCCAGTTCCTACAACACCTTTTCTCCGCCCTGTCCACCAAGTTCCCCTTGTCCCCCATGTCCCTATGGTTAGGCCTGCTCACCAG
CTTCACCCAGGGTTGGTACAGAGGATGCTGGCCCAGGGAGTACATCCACAGCATCTTCCAAGTTTGCTCCAAACTGGTGTGCTTCCTCCT
GGGATGGACTTGAGTCATTTACAGGGAATATCTGGCCCCATCCTGGGTCAGCCCTTTTACCCTTTACCTGCTGCTAGTCACCCTCTCTTA
AACCCTCGTCCTGGAACACCTCTGCATCTGGCAATGGTGCAACAGCAGCTACAGCGCTCAGTTCTGCATCCTCCAGGCTCTGGTTCCCAT
GCAGCAGCTGTCAGCGTTCAGACAACCCCTCAGAACGTGCCCAGCCGGTCAGGCCTGCCCCACATGCACTCCCAGCTGGAGCATCGCCCC
AGCCAGAGGAGCAGCTCCCCTGTGGGCCTTGCCAAATGGTTTGGCTCAGATGTGCTACAGCAACCCCTGCCCTCCATGCCCGCCAAAGTT
ATCAGTGTAGATGAATTGGAATACCGACAGTGAGCAGGGCAGGCAGACTCAACTAAGCCCGGACCTGTGGTGGCACACTGGGCAGGACCC
TGCTTCATCTCGGGTTGGTTTATGGGCTTTTACTTTGGAGCACTCTGTGTGAAGCTGTTTGGTGGAACCCATGCATCTGGTGTGGTCCGC
ATTATGATGGAAGGATCTTAACCAGTCGAGTGGAGTGTACATTGTCTGAATACAGGATGCACAATGTTGTCAATCCTGGAAATGGTCTTT
CTTTTTTGTAAGATATGTGAATGAAGTGTTGGTGTCCTCACCAAGAGGTGGCACCTAAGGGTTCTGAGGAAATAAATGTATAGACCCTTA
TGTACAGACCTGTGTATAAACAACTTTTGTATATACATATAGGATAGCTTTTTTGAACTATACAGCTGTACATAAAAGTAGCTGATATTA
GTTAGGCCTGTGTCAACAGTTTGGATTTTTTTCACTTGTACATTTGGGATTTTCTTTTGGTTGATTAAAATTGCATATGCTAAGTGTGTG

>65544_65544_4_PISD-EIF4ENIF1_PISD_chr22_32044087_ENST00000336566_EIF4ENIF1_chr22_31867903_ENST00000397525_length(amino acids)=1060AA_BP=0
MATSVGHRCLGLLHGVAPWRSSLHPCEITALSQSLQPLRKLPFRAFRTDARKIHTAPARTMFLLRPLPILLVTGGGYAGYRQYEKYRERE
LEKLGLEIPPKLAGHWEEELLDIKELPHSKQRPSCLSEKYDSDGVWDPEKWHASLYPASGRSSPVESLKKELDTDRPSLVRRIVDPRERV
KEDDLDVVLSPQRRSFGGGCHVTAAVSSRRSGSPLEKDSDGLRLLGGRRIGSGRIISARTFEKDHRLSDKDLRDLRDRDRERDFKDKRFR
REFGDSKRVFGERRRNDSYTEEEPEWFSAGPTSQSETIELTGFDDKILEEDHKGRKRTRRRTASVKEGIVECNGGVAEEDEVEVILAQEP
AADQEVPRDAVLPEQSPGDFDFNEFFNLDKVPCLASMIEDVLGEGSVSASRFSRWFSNPSRSGSRSSSLGSTPHEELERLAGLEQAILSP
GQNSGNYFAPIPLEDHAENKVDILEMLQKAKVDLKPLLSSLSANKEKLKESSHSGVVLSVEEVEAGLKGLKVDQQVKNSTPFMAEHLEET
LSAVTNNRQLKKDGDMTAFNKLVSTMKASGTLPSQPKVSRNLESHLMSPAEIPGQPVPKNILQELLGQPVQRPASSNLLSGLMGSLEPTT
SLLGQRAPSPPLSQVFQTRAASADYLRPRIPSPIGFTPGPQQLLGDPFQGMRKPMSPITAQMSQLELQQAALEGLALPHDLAVQAANFYQ
PGFGKPQVDRTRDGFRNRQQRVTKSPAPVHRGNSSSPAPAASITSMLSPSFTPTSVIRKMYESKEKSKEEPASGKAALGDSKEDTQKASE
ENLLSSSSVPSADRDSSPTTNSKLSALQRSSCSTPLSQANRYTKEQDYRPKATGRKTPTLASPVPTTPFLRPVHQVPLVPHVPMVRPAHQ
LHPGLVQRMLAQGVHPQHLPSLLQTGVLPPGMDLSHLQGISGPILGQPFYPLPAASHPLLNPRPGTPLHLAMVQQQLQRSVLHPPGSGSH

--------------------------------------------------------------
>65544_65544_5_PISD-EIF4ENIF1_PISD_chr22_32044087_ENST00000439502_EIF4ENIF1_chr22_31867903_ENST00000330125_length(transcript)=3918nt_BP=545nt
CTGCGACCAAGCCCAGGTTTAGCGAAACCTACAGCTCCACTAGTTCCCCTACCTCCGCAGGTGCCAAGCGGGTTAGGTGGGGAGTAGCCA
CAGGGCGGAGCTTAGTCGGCTCCGCCCCCAACCCGCGCTTTTCTCATTGGCCCACTGAACTCGAGACTCGTGACGCCTTAAGCGTGCGCC
CAGCGTGTGAAGGGGGCGTGGCACGCTGAGAAGGAGCAGACAAGATGGCGACGTCCGTGGGGCACCGATGTCTGGGATTACTGCACGGGG
TCGCGCCGTGGCGGAGCAGCCTCCATCCCTGTGAGATCACTGCCCTGAGCCAATCCCTACAGCCCTTACGGAAGCTGCCTTTTAGAGCCT
TTCGCACAGATGCCAGAAAAATCCACACTGCCCCTGCCCGAACCATGTTCCTGCTGCGTCCCCTGCCCATTCTGTTGGTGACAGGCGGCG
GGTATGCAGGGTACCGGCAGTATGAGAAGTACAGGGAGCGAGAGCTGGAGAAGCTGGGATTGGAGATTCCACCCAAACTTGCTGGTCACT
GGGAGGAAGAACTCTTGGATATAAAAGAACTCCCCCATTCCAAACAGAGGCCTTCATGCCTTTCTGAAAAATATGACAGTGATGGTGTCT
GGGACCCTGAGAAGTGGCATGCCTCTCTCTACCCAGCTTCAGGGCGGAGCTCACCAGTGGAAAGTCTGAAGAAAGAGTTGGATACAGACC
GGCCTTCCCTGGTGCGCAGGATAGTAGATCCACGAGAGCGTGTGAAAGAAGATGACTTAGATGTTGTTCTCAGCCCTCAGAGACGGAGCT
TTGGAGGGGGCTGCCACGTGACAGCCGCTGTTAGCTCCCGGCGCTCAGGAAGTCCATTAGAGAAAGATAGTGATGGGCTTCGTCTGCTTG
GTGGACGTAGGATTGGCAGTGGGAGGATAATCTCTGCCCGGACCTTTGAGAAGGATCACCGTCTTAGCGATAAGGACCTGCGGGACTTGA
GAGACAGAGACCGAGAGAGGGACTTCAAGGACAAGCGTTTCAGGAGAGAGTTTGGAGATAGTAAGCGTGTCTTTGGTGAGCGTAGAAGAA
ATGATTCTTACACAGAAGAAGAACCAGAGTGGTTCTCTGCTGGACCCACAAGTCAGTCTGAAACCATCGAACTGACTGGCTTTGATGATA
AGATACTAGAAGAAGATCACAAAGGGAGAAAAAGAACAAGGCGACGGACAGCCTCTGTGAAGGAAGGTATAGTAGAGTGCAATGGAGGAG
TGGCCGAAGAGGATGAAGTGGAGGTCATCCTTGCACAGGAGCCTGCGGCTGATCAGGAAGTGCCAAGGGATGCTGTCTTGCCTGAGCAGT
CCCCAGGAGACTTTGACTTTAATGAGTTCTTTAACCTTGATAAGGTGCCATGCTTGGCTTCGATGATAGAAGATGTTTTGGGAGAAGGGT
CAGTCTCTGCCAGTCGGTTCAGTAGGTGGTTCTCTAACCCGAGCAGATCAGGAAGCCGATCCAGCAGTCTTGGGTCAACACCACATGAAG
AGCTAGAGAGACTTGCAGGTCTGGAGCAAGCCATCCTCTCTCCTGGACAGAACTCGGGGAATTACTTTGCTCCTATACCATTGGAAGACC
ATGCTGAAAATAAAGTGGATATTTTAGAAATGCTACAGAAAGCCAAAGTGGATTTGAAACCTCTTCTTTCCAGCCTTTCTGCAAATAAAG
AAAAACTTAAAGAAAGCTCACATTCAGGGGTTGTGCTTTCAGTGGAGGAGGTAGAAGCAGGTCTGAAGGGCTTGAAGGTTGACCAGCAAG
TGAAGAATTCAACTCCCTTCATGGCAGAACACCTAGAAGAGACCTTGAGTGCCGTAACCAACAATCGACAACTGAAGAAAGACGGAGACA
TGACTGCGTTCAACAAGCTAGTGAGCACAATGAAGGCAAGTGGGACTTTGCCTTCTCAGCCCAAAGTCAGCCGAAACCTTGAAAGCCATT
TGATGTCCCCTGCTGAGATTCCAGGCCAGCCTGTCCCTAAGAACATCCTGCAGGAACTTCTGGGTCAACCAGTTCAGAGACCTGCTTCTT
CCAATCTTCTGAGTGGCCTTATGGGGAGCTTGGAGCCTACAACATCTTTACTGGGCCAAAGAGCACCCTCTCCTCCCTTGTCACAGGTGT
TTCAAACTCGAGCAGCCTCAGCTGACTACCTTCGCCCAAGAATACCATCACCAATTGGTTTCACACCAGGACCACAGCAGCTACTCGGAG
ATCCATTCCAAGGCATGCGCAAACCCATGAGCCCCATCACAGCCCAGATGAGCCAGCTGGAGTTGCAACAGGCAGCTTTAGAAGGGCTGG
CCTTGCCACATGACCTTGCTGTACAGGCAGCAAACTTCTACCAGCCTGGTTTTGGCAAACCACAGGTGGACAGAACCAGAGATGGATTCA
GAAACAGGCAACAGCGAGTGACCAAGTCACCAGCACCCGTGCATCGAGGGAATTCCTCTTCCCCTGCCCCTGCTGCCTCCATCACAAGCA
TGCTTTCTCCTTCCTTTACCCCTACCTCAGTGATTCGTAAGATGTACGAGAGCAAAGAGAAAAGCAAGGAGGAGCCAGCATCTGGAAAAG
CAGCTCTTGGTGACAGTAAAGAGGATACTCAGAAGGCCAGTGAAGAAAACCTCCTGTCATCCAGCTCTGTACCCAGTGCCGATCGAGACT
CTTCTCCCACTACAAATTCCAAACTGTCAGCATTACAGAGGTCTTCGTGTTCCACCCCACTGTCCCAGGCCAACCGTTACACCAAAGAAC
AAGATTATCGACCTAAAGCAACTGGGAGAAAAACACCCACCTTGGCATCCCCAGTTCCTACAACACCTTTTCTCCGCCCTGTCCACCAAG
TTCCCCTTGTCCCCCATGTCCCTATGGTTAGGCCTGCTCACCAGCTTCACCCAGGGTTGGTACAGAGGATGCTGGCCCAGGGAGTACATC
CACAGCATCTTCCAAGTTTGCTCCAAACTGGTGTGCTTCCTCCTGGGATGGACTTGAGTCATTTACAGGGAATATCTGGCCCCATCCTGG
GTCAGCCCTTTTACCCTTTACCTGCTGCTAGTCACCCTCTCTTAAACCCTCGTCCTGGAACACCTCTGCATCTGGCAATGGTGCAACAGC
AGCTACAGCGCTCAGTTCTGCATCCTCCAGGCTCTGGTTCCCATGCAGCAGCTGTCAGCGTTCAGACAACCCCTCAGAACGTGCCCAGCC
GGTCAGGCCTGCCCCACATGCACTCCCAGCTGGAGCATCGCCCCAGCCAGAGGAGCAGCTCCCCTGTGGGCCTTGCCAAATGGTTTGGCT
CAGATGTGCTACAGCAACCCCTGCCCTCCATGCCCGCCAAAGTTATCAGTGTAGATGAATTGGAATACCGACAGTGAGCAGGGCAGGCAG
ACTCAACTAAGCCCGGACCTGTGGTGGCACACTGGGCAGGACCCTGCTTCATCTCGGGTTGGTTTATGGGCTTTTACTTTGGAGCACTCT
GTGTGAAGCTGTTTGGTGGAACCCATGCATCTGGTGTGGTCCGCATTATGATGGAAGGATCTTAACCAGTCGAGTGGAGTGTACATTGTC
TGAATACAGGATGCACAATGTTGTCAATCCTGGAAATGGTCTTTCTTTTTTGTAAGATATGTGAATGAAGTGTTGGTGTCCTCACCAAGA
GGTGGCACCTAAGGGTTCTGAGGAAATAAATGTATAGACCCTTATGTACAGACCTGTGTATAAACAACTTTTGTATATACATATAGGATA
GCTTTTTTGAACTATACAGCTGTACATAAAAGTAGCTGATATTAGTTAGGCCTGTGTCAACAGTTTGGATTTTTTTCACTTGTACATTTG

>65544_65544_5_PISD-EIF4ENIF1_PISD_chr22_32044087_ENST00000439502_EIF4ENIF1_chr22_31867903_ENST00000330125_length(amino acids)=1060AA_BP=0
MATSVGHRCLGLLHGVAPWRSSLHPCEITALSQSLQPLRKLPFRAFRTDARKIHTAPARTMFLLRPLPILLVTGGGYAGYRQYEKYRERE
LEKLGLEIPPKLAGHWEEELLDIKELPHSKQRPSCLSEKYDSDGVWDPEKWHASLYPASGRSSPVESLKKELDTDRPSLVRRIVDPRERV
KEDDLDVVLSPQRRSFGGGCHVTAAVSSRRSGSPLEKDSDGLRLLGGRRIGSGRIISARTFEKDHRLSDKDLRDLRDRDRERDFKDKRFR
REFGDSKRVFGERRRNDSYTEEEPEWFSAGPTSQSETIELTGFDDKILEEDHKGRKRTRRRTASVKEGIVECNGGVAEEDEVEVILAQEP
AADQEVPRDAVLPEQSPGDFDFNEFFNLDKVPCLASMIEDVLGEGSVSASRFSRWFSNPSRSGSRSSSLGSTPHEELERLAGLEQAILSP
GQNSGNYFAPIPLEDHAENKVDILEMLQKAKVDLKPLLSSLSANKEKLKESSHSGVVLSVEEVEAGLKGLKVDQQVKNSTPFMAEHLEET
LSAVTNNRQLKKDGDMTAFNKLVSTMKASGTLPSQPKVSRNLESHLMSPAEIPGQPVPKNILQELLGQPVQRPASSNLLSGLMGSLEPTT
SLLGQRAPSPPLSQVFQTRAASADYLRPRIPSPIGFTPGPQQLLGDPFQGMRKPMSPITAQMSQLELQQAALEGLALPHDLAVQAANFYQ
PGFGKPQVDRTRDGFRNRQQRVTKSPAPVHRGNSSSPAPAASITSMLSPSFTPTSVIRKMYESKEKSKEEPASGKAALGDSKEDTQKASE
ENLLSSSSVPSADRDSSPTTNSKLSALQRSSCSTPLSQANRYTKEQDYRPKATGRKTPTLASPVPTTPFLRPVHQVPLVPHVPMVRPAHQ
LHPGLVQRMLAQGVHPQHLPSLLQTGVLPPGMDLSHLQGISGPILGQPFYPLPAASHPLLNPRPGTPLHLAMVQQQLQRSVLHPPGSGSH

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>65544_65544_6_PISD-EIF4ENIF1_PISD_chr22_32044087_ENST00000439502_EIF4ENIF1_chr22_31867903_ENST00000344710_length(transcript)=3402nt_BP=545nt
CTGCGACCAAGCCCAGGTTTAGCGAAACCTACAGCTCCACTAGTTCCCCTACCTCCGCAGGTGCCAAGCGGGTTAGGTGGGGAGTAGCCA
CAGGGCGGAGCTTAGTCGGCTCCGCCCCCAACCCGCGCTTTTCTCATTGGCCCACTGAACTCGAGACTCGTGACGCCTTAAGCGTGCGCC
CAGCGTGTGAAGGGGGCGTGGCACGCTGAGAAGGAGCAGACAAGATGGCGACGTCCGTGGGGCACCGATGTCTGGGATTACTGCACGGGG
TCGCGCCGTGGCGGAGCAGCCTCCATCCCTGTGAGATCACTGCCCTGAGCCAATCCCTACAGCCCTTACGGAAGCTGCCTTTTAGAGCCT
TTCGCACAGATGCCAGAAAAATCCACACTGCCCCTGCCCGAACCATGTTCCTGCTGCGTCCCCTGCCCATTCTGTTGGTGACAGGCGGCG
GGTATGCAGGGTACCGGCAGTATGAGAAGTACAGGGAGCGAGAGCTGGAGAAGCTGGGATTGGAGATTCCACCCAAACTTGCTGGTCACT
GGGAGGAAGAACTCTTGGATATAAAAGAACTCCCCCATTCCAAACAGAGGCCTTCATGCCTTTCTGAAAAATATGACAGTGATGGTGTCT
GGGACCCTGAGAAGTGGCATGCCTCTCTCTACCCAGCTTCAGGGCGGAGCTCACCAGTGGAAAGTCTGAAGAAAGAGTTGGATACAGACC
GGCCTTCCCTGGTGCGCAGGATAGTAGGTATAGTAGAGTGCAATGGAGGAGTGGCCGAAGAGGATGAAGTGGAGGTCATCCTTGCACAGG
AGCCTGCGGCTGATCAGGAAGTGCCAAGGGATGCTGTCTTGCCTGAGCAGTCCCCAGGAGACTTTGACTTTAATGAGTTCTTTAACCTTG
ATAAGGTGCCATGCTTGGCTTCGATGATAGAAGATGTTTTGGGAGAAGGGTCAGTCTCTGCCAGTCGGTTCAGTAGGTGGTTCTCTAACC
CGAGCAGATCAGGAAGCCGATCCAGCAGTCTTGGGTCAACACCACATGAAGAGCTAGAGAGACTTGCAGGTCTGGAGCAAGCCATCCTCT
CTCCTGGACAGAACTCGGGGAATTACTTTGCTCCTATACCATTGGAAGACCATGCTGAAAATAAAGTGGATATTTTAGAAATGCTACAGA
AAGCCAAAGTGGATTTGAAACCTCTTCTTTCCAGCCTTTCTGCAAATAAAGAAAAACTTAAAGAAAGCTCACATTCAGGGGTTGTGCTTT
CAGTGGAGGAGGTAGAAGCAGGTCTGAAGGGCTTGAAGGTTGACCAGCAAGTGAAGAATTCAACTCCCTTCATGGCAGAACACCTAGAAG
AGACCTTGAGTGCCGTAACCAACAATCGACAACTGAAGAAAGACGGAGACATGACTGCGTTCAACAAGCTAGTGAGCACAATGAAGCGAA
ACCTTGAAAGCCATTTGATGTCCCCTGCTGAGATTCCAGGCCAGCCTGTCCCTAAGAACATCCTGCAGGAACTTCTGGGTCAACCAGTTC
AGAGACCTGCTTCTTCCAATCTTCTGAGTGGCCTTATGGGGAGCTTGGAGCCTACAACATCTTTACTGGGCCAAAGAGCACCCTCTCCTC
CCTTGTCACAGGTGTTTCAAACTCGAGCAGCCTCAGCTGACTACCTTCGCCCAAGAATACCATCACCAATTGGTTTCACACCAGGACCAC
AGCAGCTACTCGGAGATCCATTCCAAGGCATGCGCAAACCCATGAGCCCCATCACAGCCCAGCAGATGAGCCAGCTGGAGTTGCAACAGG
CAGCTTTAGAAGGGCTGGCCTTGCCACATGACCTTGCTGTACAGGCAGCAAACTTCTACCAGCCTGGTTTTGGCAAACCACAGGTGGACA
GAACCAGAGATGGATTCAGAAACAGGCAACAGCGAGTGACCAAGTCACCAGCACCCGTGCATCGAGGGAATTCCTCTTCCCCTGCCCCTG
CTGCCTCCATCACAAGCATGCTTTCTCCTTCCTTTACCCCTACCTCAGTGATTCGTAAGATGTACGAGAGCAAAGAGAAAAGCAAGGAGG
AGCCAGCATCTGGAAAAGCAGCTCTTGGTGACAGTAAAGAGGATACTCAGAAGGCCAGTGAAGAAAACCTCCTGTCATCCAGCTCTGTAC
CCAGTGCCGATCGAGACTCTTCTCCCACTACAAATTCCAAACTGTCAGCATTACAGAGGTCTTCGTGTTCCACCCCACTGTCCCAGGCCA
ACCGTTACACCAAAGAACAAGATTATCGACCTAAAGCAACTGGGAGAAAAACACCCACCTTGGCATCCCCAGTTCCTACAACACCTTTTC
TCCGCCCTGTCCACCAAGTTCCCCTTGTCCCCCATGTCCCTATGGTTAGGCCTGCTCACCAGCTTCACCCAGGGTTGGTACAGAGGATGC
TGGCCCAGGGAGTACATCCACAGCATCTTCCAAGTTTGCTCCAAACTGGTGTGCTTCCTCCTGGGATGGACTTGAGTCATTTACAGGGAA
TATCTGGCCCCATCCTGGGTCAGCCCTTTTACCCTTTACCTGCTGCTAGTCACCCTCTCTTAAACCCTCGTCCTGGAACACCTCTGCATC
TGGCAATGGTGCAACAGCAGCTACAGCGCTCAGTTCTGCATCCTCCAGGCTCTGGTTCCCATGCAGCAGCTGTCAGCGTTCAGACAACCC
CTCAGAACGTGCCCAGCCGGTCAGGCCTGCCCCACATGCACTCCCAGCTGGAGCATCGCCCCAGCCAGAGGAGCAGCTCCCCTGTGGGCC
TTGCCAAATGGTTTGGCTCAGATGTGCTACAGCAACCCCTGCCCTCCATGCCCGCCAAAGTTATCAGTGTAGATGAATTGGAATACCGAC
AGTGAGCAGGGCAGGCAGACTCAACTAAGCCCGGACCTGTGGTGGCACACTGGGCAGGACCCTGCTTCATCTCGGGTTGGTTTATGGGCT
TTTACTTTGGAGCACTCTGTGTGAAGCTGTTTGGTGGAACCCATGCATCTGGTGTGGTCCGCATTATGATGGAAGGATCTTAACCAGTCG
AGTGGAGTGTACATTGTCTGAATACAGGATGCACAATGTTGTCAATCCTGGAAATGGTCTTTCTTTTTTGTAAGATATGTGAATGAAGTG
TTGGTGTCCTCACCAAGAGGTGGCACCTAAGGGTTCTGAGGAAATAAATGTATAGACCCTTATGTACAGACCTGTGTATAAACAACTTTT
GTATATACATATAGGATAGCTTTTTTGAACTATACAGCTGTACATAAAAGTAGCTGATATTAGTTAGGCCTGTGTCAACAGTTTGGATTT

>65544_65544_6_PISD-EIF4ENIF1_PISD_chr22_32044087_ENST00000439502_EIF4ENIF1_chr22_31867903_ENST00000344710_length(amino acids)=886AA_BP=0
MATSVGHRCLGLLHGVAPWRSSLHPCEITALSQSLQPLRKLPFRAFRTDARKIHTAPARTMFLLRPLPILLVTGGGYAGYRQYEKYRERE
LEKLGLEIPPKLAGHWEEELLDIKELPHSKQRPSCLSEKYDSDGVWDPEKWHASLYPASGRSSPVESLKKELDTDRPSLVRRIVGIVECN
GGVAEEDEVEVILAQEPAADQEVPRDAVLPEQSPGDFDFNEFFNLDKVPCLASMIEDVLGEGSVSASRFSRWFSNPSRSGSRSSSLGSTP
HEELERLAGLEQAILSPGQNSGNYFAPIPLEDHAENKVDILEMLQKAKVDLKPLLSSLSANKEKLKESSHSGVVLSVEEVEAGLKGLKVD
QQVKNSTPFMAEHLEETLSAVTNNRQLKKDGDMTAFNKLVSTMKRNLESHLMSPAEIPGQPVPKNILQELLGQPVQRPASSNLLSGLMGS
LEPTTSLLGQRAPSPPLSQVFQTRAASADYLRPRIPSPIGFTPGPQQLLGDPFQGMRKPMSPITAQQMSQLELQQAALEGLALPHDLAVQ
AANFYQPGFGKPQVDRTRDGFRNRQQRVTKSPAPVHRGNSSSPAPAASITSMLSPSFTPTSVIRKMYESKEKSKEEPASGKAALGDSKED
TQKASEENLLSSSSVPSADRDSSPTTNSKLSALQRSSCSTPLSQANRYTKEQDYRPKATGRKTPTLASPVPTTPFLRPVHQVPLVPHVPM
VRPAHQLHPGLVQRMLAQGVHPQHLPSLLQTGVLPPGMDLSHLQGISGPILGQPFYPLPAASHPLLNPRPGTPLHLAMVQQQLQRSVLHP

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>65544_65544_7_PISD-EIF4ENIF1_PISD_chr22_32044087_ENST00000439502_EIF4ENIF1_chr22_31867903_ENST00000397523_length(transcript)=3842nt_BP=545nt
CTGCGACCAAGCCCAGGTTTAGCGAAACCTACAGCTCCACTAGTTCCCCTACCTCCGCAGGTGCCAAGCGGGTTAGGTGGGGAGTAGCCA
CAGGGCGGAGCTTAGTCGGCTCCGCCCCCAACCCGCGCTTTTCTCATTGGCCCACTGAACTCGAGACTCGTGACGCCTTAAGCGTGCGCC
CAGCGTGTGAAGGGGGCGTGGCACGCTGAGAAGGAGCAGACAAGATGGCGACGTCCGTGGGGCACCGATGTCTGGGATTACTGCACGGGG
TCGCGCCGTGGCGGAGCAGCCTCCATCCCTGTGAGATCACTGCCCTGAGCCAATCCCTACAGCCCTTACGGAAGCTGCCTTTTAGAGCCT
TTCGCACAGATGCCAGAAAAATCCACACTGCCCCTGCCCGAACCATGTTCCTGCTGCGTCCCCTGCCCATTCTGTTGGTGACAGGCGGCG
GGTATGCAGGGTACCGGCAGTATGAGAAGTACAGGGAGCGAGAGCTGGAGAAGCTGGGATTGGAGATTCCACCCAAACTTGCTGGTCACT
GGGAGGAAGAACTCTTGGATATAAAAGAACTCCCCCATTCCAAACAGAGGCCTTCATGCCTTTCTGAAAAATATGACAGTGATGGTGTCT
GGGACCCTGAGAAGTGGCATGCCTCTCTCTACCCAGCTTCAGGGCGGAGCTCACCAGTGGAAAGTCTGAAGAAAGAGTTGGATACAGACC
GGCCTTCCCTGGTGCGCAGGATAGTAGATCCACGAGAGCGTGTGAAAGAAGATGACTTAGATGTTGTTCTCAGCCCTCAGAGACGGAGCT
TTGGAGGGGGCTGCCACGTGACAGCCGCTGTTAGCTCCCGGCGCTCAGGAAGTCCATTAGAGAAAGATAGTGATGGGCTTCGTCTGCTTG
GTGGACGTAGGATTGGCAGTGGGAGGATAATCTCTGCCCGGACCTTTGAGAAGGATCACCGTCTTAGCGATAAGGACCTGCGGGACTTGA
GAGACAGAGACCGAGAGAGGGACTTCAAGGACAAGCGTTTCAGGAGAGAGTTTGGAGATAGTAAGCGTGTCTTTGGTGAGCGTAGAAGAA
ATGATTCTTACACAGAAGAAGAACCAGAGTGGTTCTCTGCTGGACCCACAAGTCAGTCTGAAACCATCGAACTGACTGGCTTTGATGATA
AGATACTAGAAGAAGATCACAAAGGGAGAAAAAGAACAAGGCGACGGACAGCCTCTGTGAAGGAAGGTATAGTAGAGTGCAATGGAGGAG
TGGCCGAAGAGGATGAAGTGGAGGTCATCCTTGCACAGGAGCCTGCGGCTGATCAGGAAGTGCCAAGGGATGCTGTCTTGCCTGAGCAGT
CCCCAGGAGACTTTGACTTTAATGAGTTCTTTAACCTTGATAAGGTGCCATGCTTGGCTTCGATGATAGAAGATGTTTTGGGAGAAGGGT
CAGTCTCTGCCAGTCGGTTCAGTAGGTGGTTCTCTAACCCGAGCAGATCAGGAAGCCGATCCAGCAGTCTTGGGTCAACACCACATGAAG
AGCTAGAGAGACTTGCAGGTCTGGAGCAAGCCATCCTCTCTCCTGGACAGAACTCGGGGAATTACTTTGCTCCTATACCATTGGAAGACC
ATGCTGAAAATAAAGTGGATATTTTAGAAATGCTACAGAAAGCCAAAGTGGATTTGAAACCTCTTCTTTCCAGCCTTTCTGCAAATAAAG
AAAAACTTAAAGAAAGCTCACATTCAGGGGTTGTGCTTTCAGTGGAGGAGGTAGAAGCAGGTCTGAAGGGCTTGAAGGTTGACCAGCAAG
TGAAGAATTCAACTCCCTTCATGGCAGAACACCTAGAAGAGACCTTGAGTGCCGTAACCAACAATCGACAACTGAAGAAAGACGGAGACA
TGACTGCGTTCAACAAGCTAGTGAGCACAATGAAGGCAAGTGGGACTTTGCCTTCTCAGCCCAAAGTCAGCGAACTTCTGGGTCAACCAG
TTCAGAGACCTGCTTCTTCCAATCTTCTGAGTGGCCTTATGGGGAGCTTGGAGCCTACAACATCTTTACTGGGCCAAAGAGCACCCTCTC
CTCCCTTGTCACAGGTGTTTCAAACTCGAGCAGCCTCAGCTGACTACCTTCGCCCAAGAATACCATCACCAATTGGTTTCACACCAGGAC
CACAGCAGCTACTCGGAGATCCATTCCAAGGCATGCGCAAACCCATGAGCCCCATCACAGCCCAGATGAGCCAGCTGGAGTTGCAACAGG
CAGCTTTAGAAGGGCTGGCCTTGCCACATGACCTTGCTGTACAGGCAGCAAACTTCTACCAGCCTGGTTTTGGCAAACCACAGGTGGACA
GAACCAGAGATGGATTCAGAAACAGGCAACAGCGAGTGACCAAGTCACCAGCACCCGTGCATCGAGGGAATTCCTCTTCCCCTGCCCCTG
CTGCCTCCATCACAAGCATGCTTTCTCCTTCCTTTACCCCTACCTCAGTGATTCGTAAGATGTACGAGAGCAAAGAGAAAAGCAAGGAGG
AGCCAGCATCTGGAAAAGCAGCTCTTGGTGACAGTAAAGAGGATACTCAGAAGGCCAGTGAAGAAAACCTCCTGTCATCCAGCTCTGTAC
CCAGTGCCGATCGAGACTCTTCTCCCACTACAAATTCCAAACTGTCAGCATTACAGAGGTCTTCGTGTTCCACCCCACTGTCCCAGGCCA
ACCGTTACACCAAAGAACAAGATTATCGACCTAAAGCAACTGGGAGAAAAACACCCACCTTGGCATCCCCAGTTCCTACAACACCTTTTC
TCCGCCCTGTCCACCAAGTTCCCCTTGTCCCCCATGTCCCTATGGTTAGGCCTGCTCACCAGCTTCACCCAGGGTTGGTACAGAGGATGC
TGGCCCAGGGAGTACATCCACAGCATCTTCCAAGTTTGCTCCAAACTGGTGTGCTTCCTCCTGGGATGGACTTGAGTCATTTACAGGGAA
TATCTGGCCCCATCCTGGGTCAGCCCTTTTACCCTTTACCTGCTGCTAGTCACCCTCTCTTAAACCCTCGTCCTGGAACACCTCTGCATC
TGGCAATGGTGCAACAGCAGCTACAGCGCTCAGTTCTGCATCCTCCAGGCTCTGGTTCCCATGCAGCAGCTGTCAGCGTTCAGACAACCC
CTCAGAACGTGCCCAGCCGGTCAGGCCTGCCCCACATGCACTCCCAGCTGGAGCATCGCCCCAGCCAGAGGAGCAGCTCCCCTGTGGGCC
TTGCCAAATGGTTTGGCTCAGATGTGCTACAGCAACCCCTGCCCTCCATGCCCGCCAAAGTTATCAGTGTAGATGAATTGGAATACCGAC
AGTGAGCAGGGCAGGCAGACTCAACTAAGCCCGGACCTGTGGTGGCACACTGGGCAGGACCCTGCTTCATCTCGGGTTGGTTTATGGGCT
TTTACTTTGGAGCACTCTGTGTGAAGCTGTTTGGTGGAACCCATGCATCTGGTGTGGTCCGCATTATGATGGAAGGATCTTAACCAGTCG
AGTGGAGTGTACATTGTCTGAATACAGGATGCACAATGTTGTCAATCCTGGAAATGGTCTTTCTTTTTTGTAAGATATGTGAATGAAGTG
TTGGTGTCCTCACCAAGAGGTGGCACCTAAGGGTTCTGAGGAAATAAATGTATAGACCCTTATGTACAGACCTGTGTATAAACAACTTTT
GTATATACATATAGGATAGCTTTTTTGAACTATACAGCTGTACATAAAAGTAGCTGATATTAGTTAGGCCTGTGTCAACAGTTTGGATTT

>65544_65544_7_PISD-EIF4ENIF1_PISD_chr22_32044087_ENST00000439502_EIF4ENIF1_chr22_31867903_ENST00000397523_length(amino acids)=1036AA_BP=0
MATSVGHRCLGLLHGVAPWRSSLHPCEITALSQSLQPLRKLPFRAFRTDARKIHTAPARTMFLLRPLPILLVTGGGYAGYRQYEKYRERE
LEKLGLEIPPKLAGHWEEELLDIKELPHSKQRPSCLSEKYDSDGVWDPEKWHASLYPASGRSSPVESLKKELDTDRPSLVRRIVDPRERV
KEDDLDVVLSPQRRSFGGGCHVTAAVSSRRSGSPLEKDSDGLRLLGGRRIGSGRIISARTFEKDHRLSDKDLRDLRDRDRERDFKDKRFR
REFGDSKRVFGERRRNDSYTEEEPEWFSAGPTSQSETIELTGFDDKILEEDHKGRKRTRRRTASVKEGIVECNGGVAEEDEVEVILAQEP
AADQEVPRDAVLPEQSPGDFDFNEFFNLDKVPCLASMIEDVLGEGSVSASRFSRWFSNPSRSGSRSSSLGSTPHEELERLAGLEQAILSP
GQNSGNYFAPIPLEDHAENKVDILEMLQKAKVDLKPLLSSLSANKEKLKESSHSGVVLSVEEVEAGLKGLKVDQQVKNSTPFMAEHLEET
LSAVTNNRQLKKDGDMTAFNKLVSTMKASGTLPSQPKVSELLGQPVQRPASSNLLSGLMGSLEPTTSLLGQRAPSPPLSQVFQTRAASAD
YLRPRIPSPIGFTPGPQQLLGDPFQGMRKPMSPITAQMSQLELQQAALEGLALPHDLAVQAANFYQPGFGKPQVDRTRDGFRNRQQRVTK
SPAPVHRGNSSSPAPAASITSMLSPSFTPTSVIRKMYESKEKSKEEPASGKAALGDSKEDTQKASEENLLSSSSVPSADRDSSPTTNSKL
SALQRSSCSTPLSQANRYTKEQDYRPKATGRKTPTLASPVPTTPFLRPVHQVPLVPHVPMVRPAHQLHPGLVQRMLAQGVHPQHLPSLLQ
TGVLPPGMDLSHLQGISGPILGQPFYPLPAASHPLLNPRPGTPLHLAMVQQQLQRSVLHPPGSGSHAAAVSVQTTPQNVPSRSGLPHMHS

--------------------------------------------------------------
>65544_65544_8_PISD-EIF4ENIF1_PISD_chr22_32044087_ENST00000439502_EIF4ENIF1_chr22_31867903_ENST00000397525_length(transcript)=3920nt_BP=545nt
CTGCGACCAAGCCCAGGTTTAGCGAAACCTACAGCTCCACTAGTTCCCCTACCTCCGCAGGTGCCAAGCGGGTTAGGTGGGGAGTAGCCA
CAGGGCGGAGCTTAGTCGGCTCCGCCCCCAACCCGCGCTTTTCTCATTGGCCCACTGAACTCGAGACTCGTGACGCCTTAAGCGTGCGCC
CAGCGTGTGAAGGGGGCGTGGCACGCTGAGAAGGAGCAGACAAGATGGCGACGTCCGTGGGGCACCGATGTCTGGGATTACTGCACGGGG
TCGCGCCGTGGCGGAGCAGCCTCCATCCCTGTGAGATCACTGCCCTGAGCCAATCCCTACAGCCCTTACGGAAGCTGCCTTTTAGAGCCT
TTCGCACAGATGCCAGAAAAATCCACACTGCCCCTGCCCGAACCATGTTCCTGCTGCGTCCCCTGCCCATTCTGTTGGTGACAGGCGGCG
GGTATGCAGGGTACCGGCAGTATGAGAAGTACAGGGAGCGAGAGCTGGAGAAGCTGGGATTGGAGATTCCACCCAAACTTGCTGGTCACT
GGGAGGAAGAACTCTTGGATATAAAAGAACTCCCCCATTCCAAACAGAGGCCTTCATGCCTTTCTGAAAAATATGACAGTGATGGTGTCT
GGGACCCTGAGAAGTGGCATGCCTCTCTCTACCCAGCTTCAGGGCGGAGCTCACCAGTGGAAAGTCTGAAGAAAGAGTTGGATACAGACC
GGCCTTCCCTGGTGCGCAGGATAGTAGATCCACGAGAGCGTGTGAAAGAAGATGACTTAGATGTTGTTCTCAGCCCTCAGAGACGGAGCT
TTGGAGGGGGCTGCCACGTGACAGCCGCTGTTAGCTCCCGGCGCTCAGGAAGTCCATTAGAGAAAGATAGTGATGGGCTTCGTCTGCTTG
GTGGACGTAGGATTGGCAGTGGGAGGATAATCTCTGCCCGGACCTTTGAGAAGGATCACCGTCTTAGCGATAAGGACCTGCGGGACTTGA
GAGACAGAGACCGAGAGAGGGACTTCAAGGACAAGCGTTTCAGGAGAGAGTTTGGAGATAGTAAGCGTGTCTTTGGTGAGCGTAGAAGAA
ATGATTCTTACACAGAAGAAGAACCAGAGTGGTTCTCTGCTGGACCCACAAGTCAGTCTGAAACCATCGAACTGACTGGCTTTGATGATA
AGATACTAGAAGAAGATCACAAAGGGAGAAAAAGAACAAGGCGACGGACAGCCTCTGTGAAGGAAGGTATAGTAGAGTGCAATGGAGGAG
TGGCCGAAGAGGATGAAGTGGAGGTCATCCTTGCACAGGAGCCTGCGGCTGATCAGGAAGTGCCAAGGGATGCTGTCTTGCCTGAGCAGT
CCCCAGGAGACTTTGACTTTAATGAGTTCTTTAACCTTGATAAGGTGCCATGCTTGGCTTCGATGATAGAAGATGTTTTGGGAGAAGGGT
CAGTCTCTGCCAGTCGGTTCAGTAGGTGGTTCTCTAACCCGAGCAGATCAGGAAGCCGATCCAGCAGTCTTGGGTCAACACCACATGAAG
AGCTAGAGAGACTTGCAGGTCTGGAGCAAGCCATCCTCTCTCCTGGACAGAACTCGGGGAATTACTTTGCTCCTATACCATTGGAAGACC
ATGCTGAAAATAAAGTGGATATTTTAGAAATGCTACAGAAAGCCAAAGTGGATTTGAAACCTCTTCTTTCCAGCCTTTCTGCAAATAAAG
AAAAACTTAAAGAAAGCTCACATTCAGGGGTTGTGCTTTCAGTGGAGGAGGTAGAAGCAGGTCTGAAGGGCTTGAAGGTTGACCAGCAAG
TGAAGAATTCAACTCCCTTCATGGCAGAACACCTAGAAGAGACCTTGAGTGCCGTAACCAACAATCGACAACTGAAGAAAGACGGAGACA
TGACTGCGTTCAACAAGCTAGTGAGCACAATGAAGGCAAGTGGGACTTTGCCTTCTCAGCCCAAAGTCAGCCGAAACCTTGAAAGCCATT
TGATGTCCCCTGCTGAGATTCCAGGCCAGCCTGTCCCTAAGAACATCCTGCAGGAACTTCTGGGTCAACCAGTTCAGAGACCTGCTTCTT
CCAATCTTCTGAGTGGCCTTATGGGGAGCTTGGAGCCTACAACATCTTTACTGGGCCAAAGAGCACCCTCTCCTCCCTTGTCACAGGTGT
TTCAAACTCGAGCAGCCTCAGCTGACTACCTTCGCCCAAGAATACCATCACCAATTGGTTTCACACCAGGACCACAGCAGCTACTCGGAG
ATCCATTCCAAGGCATGCGCAAACCCATGAGCCCCATCACAGCCCAGATGAGCCAGCTGGAGTTGCAACAGGCAGCTTTAGAAGGGCTGG
CCTTGCCACATGACCTTGCTGTACAGGCAGCAAACTTCTACCAGCCTGGTTTTGGCAAACCACAGGTGGACAGAACCAGAGATGGATTCA
GAAACAGGCAACAGCGAGTGACCAAGTCACCAGCACCCGTGCATCGAGGGAATTCCTCTTCCCCTGCCCCTGCTGCCTCCATCACAAGCA
TGCTTTCTCCTTCCTTTACCCCTACCTCAGTGATTCGTAAGATGTACGAGAGCAAAGAGAAAAGCAAGGAGGAGCCAGCATCTGGAAAAG
CAGCTCTTGGTGACAGTAAAGAGGATACTCAGAAGGCCAGTGAAGAAAACCTCCTGTCATCCAGCTCTGTACCCAGTGCCGATCGAGACT
CTTCTCCCACTACAAATTCCAAACTGTCAGCATTACAGAGGTCTTCGTGTTCCACCCCACTGTCCCAGGCCAACCGTTACACCAAAGAAC
AAGATTATCGACCTAAAGCAACTGGGAGAAAAACACCCACCTTGGCATCCCCAGTTCCTACAACACCTTTTCTCCGCCCTGTCCACCAAG
TTCCCCTTGTCCCCCATGTCCCTATGGTTAGGCCTGCTCACCAGCTTCACCCAGGGTTGGTACAGAGGATGCTGGCCCAGGGAGTACATC
CACAGCATCTTCCAAGTTTGCTCCAAACTGGTGTGCTTCCTCCTGGGATGGACTTGAGTCATTTACAGGGAATATCTGGCCCCATCCTGG
GTCAGCCCTTTTACCCTTTACCTGCTGCTAGTCACCCTCTCTTAAACCCTCGTCCTGGAACACCTCTGCATCTGGCAATGGTGCAACAGC
AGCTACAGCGCTCAGTTCTGCATCCTCCAGGCTCTGGTTCCCATGCAGCAGCTGTCAGCGTTCAGACAACCCCTCAGAACGTGCCCAGCC
GGTCAGGCCTGCCCCACATGCACTCCCAGCTGGAGCATCGCCCCAGCCAGAGGAGCAGCTCCCCTGTGGGCCTTGCCAAATGGTTTGGCT
CAGATGTGCTACAGCAACCCCTGCCCTCCATGCCCGCCAAAGTTATCAGTGTAGATGAATTGGAATACCGACAGTGAGCAGGGCAGGCAG
ACTCAACTAAGCCCGGACCTGTGGTGGCACACTGGGCAGGACCCTGCTTCATCTCGGGTTGGTTTATGGGCTTTTACTTTGGAGCACTCT
GTGTGAAGCTGTTTGGTGGAACCCATGCATCTGGTGTGGTCCGCATTATGATGGAAGGATCTTAACCAGTCGAGTGGAGTGTACATTGTC
TGAATACAGGATGCACAATGTTGTCAATCCTGGAAATGGTCTTTCTTTTTTGTAAGATATGTGAATGAAGTGTTGGTGTCCTCACCAAGA
GGTGGCACCTAAGGGTTCTGAGGAAATAAATGTATAGACCCTTATGTACAGACCTGTGTATAAACAACTTTTGTATATACATATAGGATA
GCTTTTTTGAACTATACAGCTGTACATAAAAGTAGCTGATATTAGTTAGGCCTGTGTCAACAGTTTGGATTTTTTTCACTTGTACATTTG

>65544_65544_8_PISD-EIF4ENIF1_PISD_chr22_32044087_ENST00000439502_EIF4ENIF1_chr22_31867903_ENST00000397525_length(amino acids)=1060AA_BP=0
MATSVGHRCLGLLHGVAPWRSSLHPCEITALSQSLQPLRKLPFRAFRTDARKIHTAPARTMFLLRPLPILLVTGGGYAGYRQYEKYRERE
LEKLGLEIPPKLAGHWEEELLDIKELPHSKQRPSCLSEKYDSDGVWDPEKWHASLYPASGRSSPVESLKKELDTDRPSLVRRIVDPRERV
KEDDLDVVLSPQRRSFGGGCHVTAAVSSRRSGSPLEKDSDGLRLLGGRRIGSGRIISARTFEKDHRLSDKDLRDLRDRDRERDFKDKRFR
REFGDSKRVFGERRRNDSYTEEEPEWFSAGPTSQSETIELTGFDDKILEEDHKGRKRTRRRTASVKEGIVECNGGVAEEDEVEVILAQEP
AADQEVPRDAVLPEQSPGDFDFNEFFNLDKVPCLASMIEDVLGEGSVSASRFSRWFSNPSRSGSRSSSLGSTPHEELERLAGLEQAILSP
GQNSGNYFAPIPLEDHAENKVDILEMLQKAKVDLKPLLSSLSANKEKLKESSHSGVVLSVEEVEAGLKGLKVDQQVKNSTPFMAEHLEET
LSAVTNNRQLKKDGDMTAFNKLVSTMKASGTLPSQPKVSRNLESHLMSPAEIPGQPVPKNILQELLGQPVQRPASSNLLSGLMGSLEPTT
SLLGQRAPSPPLSQVFQTRAASADYLRPRIPSPIGFTPGPQQLLGDPFQGMRKPMSPITAQMSQLELQQAALEGLALPHDLAVQAANFYQ
PGFGKPQVDRTRDGFRNRQQRVTKSPAPVHRGNSSSPAPAASITSMLSPSFTPTSVIRKMYESKEKSKEEPASGKAALGDSKEDTQKASE
ENLLSSSSVPSADRDSSPTTNSKLSALQRSSCSTPLSQANRYTKEQDYRPKATGRKTPTLASPVPTTPFLRPVHQVPLVPHVPMVRPAHQ
LHPGLVQRMLAQGVHPQHLPSLLQTGVLPPGMDLSHLQGISGPILGQPFYPLPAASHPLLNPRPGTPLHLAMVQQQLQRSVLHPPGSGSH

--------------------------------------------------------------

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Fusion Gene PPI Analysis for PISD-EIF4ENIF1


check button Go to ChiPPI (Chimeric Protein-Protein interactions) to see the chimeric PPI interaction in

ChiPPI page.


check button Protein-protein interactors with each fusion partner protein in wild-type (BIOGRID-3.4.160)
HgeneHgene's interactorsTgeneTgene's interactors


check button - Retained PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenStill interaction with
TgeneEIF4ENIF1chr22:32044087chr22:31867903ENST00000330125119131_16132.0986.0CSDE1
TgeneEIF4ENIF1chr22:32044087chr22:31867903ENST00000344710117131_16132.0812.0CSDE1
TgeneEIF4ENIF1chr22:32044087chr22:31867903ENST00000397525119131_16132.0986.0CSDE1
TgeneEIF4ENIF1chr22:32044087chr22:31867903ENST00000330125119219_24032.0986.0DDX6
TgeneEIF4ENIF1chr22:32044087chr22:31867903ENST00000344710117219_24032.0812.0DDX6
TgeneEIF4ENIF1chr22:32044087chr22:31867903ENST00000397525119219_24032.0986.0DDX6
TgeneEIF4ENIF1chr22:32044087chr22:31867903ENST00000330125119448_49032.0986.0LSM14A
TgeneEIF4ENIF1chr22:32044087chr22:31867903ENST00000330125119940_98532.0986.0LSM14A
TgeneEIF4ENIF1chr22:32044087chr22:31867903ENST00000344710117448_49032.0812.0LSM14A
TgeneEIF4ENIF1chr22:32044087chr22:31867903ENST00000344710117940_98532.0812.0LSM14A
TgeneEIF4ENIF1chr22:32044087chr22:31867903ENST00000397525119448_49032.0986.0LSM14A
TgeneEIF4ENIF1chr22:32044087chr22:31867903ENST00000397525119940_98532.0986.0LSM14A
TgeneEIF4ENIF1chr22:32044087chr22:31867903ENST00000330125119695_71332.0986.0PATL1
TgeneEIF4ENIF1chr22:32044087chr22:31867903ENST00000344710117695_71332.0812.0PATL1
TgeneEIF4ENIF1chr22:32044087chr22:31867903ENST00000397525119695_71332.0986.0PATL1


check button - Lost PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


check button - Retained PPIs, but lost function due to frame-shift fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


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Related Drugs for PISD-EIF4ENIF1


check button Drugs targeting genes involved in this fusion gene.
(DrugBank Version 5.1.8 2021-05-08)
PartnerGeneUniProtAccDrugBank IDDrug nameDrug activityDrug typeDrug status

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Related Diseases for PISD-EIF4ENIF1


check button Diseases associated with fusion partners.
(DisGeNet 4.0)
PartnerGeneDisease IDDisease name# pubmedsSource