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Center for Computational Systems Medicine
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Fusion Gene Summary

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Fusion Gene ORF analysis

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Fusion Genomic Features

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Fusion Protein Features

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Fusion Gene Sequence

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Fusion Gene PPI analysis

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Related Drugs

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Related Diseases

Fusion gene:PLA2G10-CLEC16A (FusionGDB2 ID:65835)

Fusion Gene Summary for PLA2G10-CLEC16A

check button Fusion gene summary
Fusion gene informationFusion gene name: PLA2G10-CLEC16A
Fusion gene ID: 65835
HgeneTgene
Gene symbol

PLA2G10

CLEC16A

Gene ID

8399

23274

Gene namephospholipase A2 group XC-type lectin domain containing 16A
SynonymsGXPLA2|GXSPLA2|SPLA2|sPLA2-XGop-1|KIAA0350
Cytomap

16p13.12

16p13.13

Type of geneprotein-codingprotein-coding
Descriptiongroup 10 secretory phospholipase A2group X secretory phospholipase A2phosphatidylcholine 2-acylhydrolase 10protein CLEC16AC-type lectin domain family 16 member A
Modification date2020031320200313
UniProtAcc.

Q2KHT3

Ensembl transtripts involved in fusion geneENST00000438167, ENST00000381822, 
ENST00000465491, ENST00000409552, 
ENST00000409790, 
Fusion gene scores* DoF score2 X 3 X 2=1214 X 13 X 10=1820
# samples 317
** MAII scorelog2(3/12*10)=1.32192809488736
effective Gene in Pan-Cancer Fusion Genes (eGinPCFGs).
DoF>8 and MAII>0		log2(17/1820*10)=-3.42033179894836
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0
Context

PubMed: PLA2G10 [Title/Abstract] AND CLEC16A [Title/Abstract] AND fusion [Title/Abstract]

Most frequent breakpointPLA2G10(14787990)-CLEC16A(11114050), # samples:2
Anticipated loss of major functional domain due to fusion event.PLA2G10-CLEC16A seems lost the major protein functional domain in Hgene partner, which is a cell metabolism gene due to the frame-shifted ORF.
PLA2G10-CLEC16A seems lost the major protein functional domain in Hgene partner, which is a IUPHAR drug target due to the frame-shifted ORF.
* DoF score (Degree of Frequency) = # partners X # break points X # cancer types
** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10)

check button Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez
PartnerGeneGO IDGO termPubMed ID
HgenePLA2G10

GO:0007411

axon guidance

15927955

HgenePLA2G10

GO:0043433

negative regulation of DNA-binding transcription factor activity

20844270

HgenePLA2G10

GO:0051977

lysophospholipid transport

15927955


check buttonFusion gene breakpoints across PLA2G10 (5'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.
all structure

check buttonFusion gene breakpoints across CLEC16A (3'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.
all structure

check button Fusion gene information from two resources (ChiTars 5.0 and ChimerDB 4.0)
* All genome coordinats were lifted-over on hg19.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
SourceDiseaseSampleHgeneHchrHbpHstrandTgeneTchrTbpTstrand
ChimerDB4LUADTCGA-97-7547-01APLA2G10chr16

14787990

-CLEC16Achr16

11096931

+
ChimerDB4LUADTCGA-97-7547-01APLA2G10chr16

14787990

-CLEC16Achr16

11114050

+
ChimerDB4LUADTCGA-97-7547PLA2G10chr16

14787989

-CLEC16Achr16

11096930

+


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Fusion Gene ORF analysis for PLA2G10-CLEC16A

check button Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
ORFHenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrand
5CDS-intronENST00000438167ENST00000381822PLA2G10chr16

14787990

-CLEC16Achr16

11096931

+
5CDS-intronENST00000438167ENST00000381822PLA2G10chr16

14787990

-CLEC16Achr16

11114050

+
5CDS-intronENST00000438167ENST00000381822PLA2G10chr16

14787989

-CLEC16Achr16

11096930

+
5CDS-intronENST00000438167ENST00000465491PLA2G10chr16

14787990

-CLEC16Achr16

11096931

+
5CDS-intronENST00000438167ENST00000465491PLA2G10chr16

14787990

-CLEC16Achr16

11114050

+
5CDS-intronENST00000438167ENST00000465491PLA2G10chr16

14787989

-CLEC16Achr16

11096930

+
Frame-shiftENST00000438167ENST00000409552PLA2G10chr16

14787990

-CLEC16Achr16

11114050

+
Frame-shiftENST00000438167ENST00000409790PLA2G10chr16

14787990

-CLEC16Achr16

11114050

+
In-frameENST00000438167ENST00000409552PLA2G10chr16

14787990

-CLEC16Achr16

11096931

+
In-frameENST00000438167ENST00000409552PLA2G10chr16

14787989

-CLEC16Achr16

11096930

+
In-frameENST00000438167ENST00000409790PLA2G10chr16

14787990

-CLEC16Achr16

11096931

+
In-frameENST00000438167ENST00000409790PLA2G10chr16

14787989

-CLEC16Achr16

11096930

+

check buttonORFfinder result based on the fusion transcript sequence of in-frame fusion genes.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandSeq length
(transcript)		BP loci
(transcript)		Predicted start
(transcript)		Predicted stop
(transcript)		Seq length
(amino acids)
ENST00000438167PLA2G10chr1614787989-ENST00000409790CLEC16Achr1611096930+61275373092627772
ENST00000438167PLA2G10chr1614787989-ENST00000409552CLEC16Achr1611096930+22575373092192627
ENST00000438167PLA2G10chr1614787990-ENST00000409790CLEC16Achr1611096931+61275373092627772
ENST00000438167PLA2G10chr1614787990-ENST00000409552CLEC16Achr1611096931+22575373092192627

check buttonDeepORF prediction of the coding potential based on the fusion transcript sequence of in-frame fusion genes. DeepORF is a coding potential classifier based on convolutional neural network by comparing the real Ribo-seq data. If the no-coding score < 0.5 and coding score > 0.5, then the in-frame fusion transcript is predicted as being likely translated.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandNo-coding scoreCoding score
ENST00000438167ENST00000409790PLA2G10chr1614787989-CLEC16Achr1611096930+0.0030668350.9969331
ENST00000438167ENST00000409552PLA2G10chr1614787989-CLEC16Achr1611096930+0.0197435970.98025644
ENST00000438167ENST00000409790PLA2G10chr1614787990-CLEC16Achr1611096931+0.0030668350.9969331
ENST00000438167ENST00000409552PLA2G10chr1614787990-CLEC16Achr1611096931+0.0197435970.98025644

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Fusion Genomic Features for PLA2G10-CLEC16A


check buttonFusionAI prediction of the potential fusion gene breakpoint based on the pre-mature RNA sequence context (+/- 5kb of individual partner genes, total 20kb length sequence). FusionAI is a fusion gene breakpoint classifier based on convolutional neural network by comparing the fusion positive and negative sequence context of ~ 20K fusion gene data. From here, we can have the relative potentency of the 20K genomic sequence how individual sequnce will be likely used as the gene fusion breakpoints.
HgeneHchrHbpHstrandTgeneTchrTbpTstrand1-pp (fusion gene breakpoint)
PLA2G10chr1614787989-CLEC16Achr1611114049+5.21E-121
PLA2G10chr1614787989-CLEC16Achr1611096930+1.24E-091
PLA2G10chr1614787989-CLEC16Achr1611096930+1.24E-091
PLA2G10chr1614787989-CLEC16Achr1611114049+5.21E-121
PLA2G10chr1614787989-CLEC16Achr1611096930+1.24E-091
PLA2G10chr1614787989-CLEC16Achr1611096930+1.24E-091

check buttonDistribution of 44 human genomic features loci across 20kb length fusion breakpoint regions. We integrated a total of 44 different types of human genomic feature loci information across five big categories including virus integration sites, repeats, structural variants, chromatin states, and gene expression regulation. More details are in help page.
genomic feature

check buttonDistribution of 44 human genomic features loci across 20kb length fusion breakpoint regions that are ovelapped with the top 1% feature importance score regions. More details are in help page.
genomic feature of top 1%

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Fusion Protein Features for PLA2G10-CLEC16A


check button Four levels of functional features of fusion genes
Go to FGviewer search page for the most frequent breakpoint (https://ccsmweb.uth.edu/FGviewer/chr16:14787990/chr16:11114050)
- FGviewer provides the online visualization of the retention search of the protein functional features across DNA, RNA, protein, and pathological levels.
- How to search
1. Put your fusion gene symbol.
2. Press the tab key until there will be shown the breakpoint information filled.
4. Go down and press 'Search' tab twice.
4. Go down to have the hyperlink of the search result.
5. Click the hyperlink.
6. See the FGviewer result for your fusion gene.
FGviewer

check buttonMain function of each fusion partner protein. (from UniProt)
HgeneTgene
.CLEC16A

Q2KHT3

FUNCTION: Transcriptional activator which is required for calcium-dependent dendritic growth and branching in cortical neurons. Recruits CREB-binding protein (CREBBP) to nuclear bodies. Component of the CREST-BRG1 complex, a multiprotein complex that regulates promoter activation by orchestrating a calcium-dependent release of a repressor complex and a recruitment of an activator complex. In resting neurons, transcription of the c-FOS promoter is inhibited by BRG1-dependent recruitment of a phospho-RB1-HDAC1 repressor complex. Upon calcium influx, RB1 is dephosphorylated by calcineurin, which leads to release of the repressor complex. At the same time, there is increased recruitment of CREBBP to the promoter by a CREST-dependent mechanism, which leads to transcriptional activation. The CREST-BRG1 complex also binds to the NR2B promoter, and activity-dependent induction of NR2B expression involves a release of HDAC1 and recruitment of CREBBP (By similarity). {ECO:0000250}.FUNCTION: Regulator of mitophagy through the upstream regulation of the RNF41/NRDP1-PRKN pathway. Mitophagy is a selective form of autophagy necessary for mitochondrial quality control. The RNF41/NRDP1-PRKN pathway regulates autophagosome-lysosome fusion during late mitophagy. May protect RNF41/NRDP1 from proteosomal degradation, RNF41/NRDP1 which regulates proteosomal degradation of PRKN. Plays a key role in beta cells functions by regulating mitophagy/autophagy and mitochondrial health. {ECO:0000269|PubMed:24949970}.

check buttonRetention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at

download page


* Minus value of BPloci means that the break pointn is located before the CDS.
- In-frame and retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
TgeneCLEC16Achr16:14787989chr16:11096930ENST0000038182204892_9330141.0Compositional biasNote=Ser-rich
TgeneCLEC16Achr16:14787989chr16:11096930ENST00000409552821892_933355907.0Compositional biasNote=Ser-rich
TgeneCLEC16Achr16:14787989chr16:11096930ENST00000409790924892_9333571054.0Compositional biasNote=Ser-rich
TgeneCLEC16Achr16:14787990chr16:11096931ENST0000038182204892_9330141.0Compositional biasNote=Ser-rich
TgeneCLEC16Achr16:14787990chr16:11096931ENST00000409552821892_933355907.0Compositional biasNote=Ser-rich
TgeneCLEC16Achr16:14787990chr16:11096931ENST00000409790924892_9333571054.0Compositional biasNote=Ser-rich
TgeneCLEC16Achr16:14787989chr16:11096930ENST000003818220451_1980141.0DomainFPL
TgeneCLEC16Achr16:14787990chr16:11096931ENST000003818220451_1980141.0DomainFPL

- In-frame and not-retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
TgeneCLEC16Achr16:14787989chr16:11096930ENST0000040955282151_198355907.0DomainFPL
TgeneCLEC16Achr16:14787989chr16:11096930ENST0000040979092451_1983571054.0DomainFPL
TgeneCLEC16Achr16:14787990chr16:11096931ENST0000040955282151_198355907.0DomainFPL
TgeneCLEC16Achr16:14787990chr16:11096931ENST0000040979092451_1983571054.0DomainFPL


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Fusion Gene Sequence for PLA2G10-CLEC16A


check button For in-frame fusion transcripts, we provide the fusion transcript sequences and fusion amino acid sequences. To have fusion amino acid sequence, we ran ORFfinder and chose the longest ORF among the all predicted ones.
>65835_65835_1_PLA2G10-CLEC16A_PLA2G10_chr16_14787989_ENST00000438167_CLEC16A_chr16_11096930_ENST00000409552_length(transcript)=2257nt_BP=537nt
GGCCTTCCAAAGTGCTGGGATTACAGGCGTGAGTCACCGCGCCCGGCCAAATAAAATAAAATGTTAAAGCAAATTCAGGACTACCCCTCC
TCCAAGTCTTCTGTTCCCTTTGGGCGCCCAGGTGAGCGGGGGAGGGGCTGGGGGAGTAATAACATCAAAAGAGCGCCTTTTCCTCCCTTA
TTCCGAGGAGACTTCCCTGGGCCTGACTCCCGGTCCTGTCCCCAGCGCCCCGCGGCCTCTGGAGCCCCTTCAGTGACCAAGATACAGAGA
TCAGGACGCCTTTGCGCCGCCCCAGGTGCCCGCCCCTAGCTGGCTCTGCTTGGGCCGCGAGGGAAGGTGAGGTCGGGGGCGGAGCCGGGG
CGTGACAGCCGGGGTGTGTGTCCGCCGGGCTTGGTGCCTCCGGTGGCCCTGCAGCACCGTCCCACCTCTGCCACCCTCCGATGGGGCCGC
TACCTGTGTGCCTGCCAATCATGCTGCTCCTGCTACTGCCGTCGCTGCTGCTGCTGCTGCTTCTACCTGGCCCCGGGTCCGGCGAGGGCC
AAGCCCAGCATTCGGTGCTTCATTAAACCCACCGAGACACTCGAGCGGTCCCTTGAGATGAACAAGCACAAGGGCAAGAGGCGGGTGCAA
AAGAGACCCAACTACAAAAACGTTGGGGAAGAAGAAGATGAGGAGAAAGGGCCCACCGAGGATGCCCAAGAAGACGCCGAGAAGGCTAAA
GAGATCGAGATGGTGATCATGGAGCGTAGCAAGCTCTCAGAGCTGGCCGCCAGCACCTCCGTGCAGGAGCAGAACACCACGGACGAGGAG
AAAAGCGCCGCCGCCACCTGCTCTGAGAGCACGCAATGGAGCAGACCCTTCCTGGATATGGTGTACCACGCGCTGGACAGCCCGGATGAT
GATTACCATGCCCTGTTCGTGCTCTGCCTCCTCTATGCCATGTCTCATAATAAAGGCATGGATCCTGAAAAATTAGAGCGAATCCAGCTC
CCCGTGCCAAATGCGGCCGAGAAGACCACCTACAACCACCCGCTAGCTGAAAGACTCATCAGGATCATGAACAACGCTGCCCAGCCAGAT
GGGAAGATCCGGCTGGCGACGCTGGAGCTGAGCTGCCTGCTTCTGAAGCAGCAAGTCCTGATGAGTGCTGGCTGCATCATGAAGGACGTG
CACCTGGCCTGCCTGGAGGGTGCGAGAGAAGAAAGTGTTCACCTTGTACGACATTTTTATAAGGGAGAAGACATTTTTTTGGACATGTTT
GAAGATGAGTATAGGAGCATGACAATGAAGCCCATGAACGTGGAATATCTCATGATGGACGCCTCCATCCTGCTGCCCCCAACAGGCACG
CCACTGACGGGCATTGACTTCGTGAAGCGGCTGCCGTGTGGCGATGTGGAGAAGACCCGGCGGGCCATCCGGGTGTTCTTCATGCTGCGT
TCCCTGTCACTGCAATTGCGAGGGGAGCCTGAGACACAGTTGCCGCTGACTCGGGAGGAGGACCTGATCAAGACTGATGATGTCCTGGAT
CTGAATAACAGCGACTTGATTGCATGTACAGTGATCACCAAGGATGGCGGCATGGTCCAGCGATTCCTGGCTGTGGATATTTACCAGATG
AGTTTGGTGGAGCCTGATGTGTCCAGGCTTGGCTGGGGAGTGGTCAAGTTTGCAGGCCTATTGCAGGACATGCAGGTGACTGGCGTGGAG
GACGACAGCCGTGCCCTGAACATCACCATCCACAAGCCTGCGTCCAGCCCCCATTCCAAGCCCTTCCCCATCCTCCAGGCCACCTTCATC
TTCTCAGACCACATCCGCTGCATCATCGCCAAGCAGCGCCTGGCCAAAGGCCGCATCCAGGCAAGGCGCATGAAGATGCAGAGAATAGCT
GCCCTCCTGGACCTCCCAATCCAGCCCACCACTGAAGTCCTGGGGTTTGGACTCGGCTCCTCCACCTCCACTCAGCACCTGCCTTTCCGC
TTCTACGACCAGGGGCGCCGGGGCAGCAGCGACCCCACAGTGCAGCGCTCCGTGTTTGCATCGGTGGACAAGGTGCCAGGTGAGCCAGCC
CCCCGCCCTGCGCCACAGCTCGTTCATCATGGTGGGCGTTCAAGGTCTTTCTCTCTGTGGAGCCTGTGTGAGCTGCCCTTCCTCTCTCAG
AAGCCCCGTCGGCTGGCAGCACCAGCTTCTTAGAATTTGTCAAAGCACAGCGCAAGATTAAACACAGCCCCCAAAATAAATTTTGGCTTT

>65835_65835_1_PLA2G10-CLEC16A_PLA2G10_chr16_14787989_ENST00000438167_CLEC16A_chr16_11096930_ENST00000409552_length(amino acids)=627AA_BP=71
MALLGPRGKVRSGAEPGRDSRGVCPPGLVPPVALQHRPTSATLRWGRYLCACQSCCSCYCRRCCCCCFYLAPGPARAKPSIRCFIKPTET
LERSLEMNKHKGKRRVQKRPNYKNVGEEEDEEKGPTEDAQEDAEKAKEIEMVIMERSKLSELAASTSVQEQNTTDEEKSAAATCSESTQW
SRPFLDMVYHALDSPDDDYHALFVLCLLYAMSHNKGMDPEKLERIQLPVPNAAEKTTYNHPLAERLIRIMNNAAQPDGKIRLATLELSCL
LLKQQVLMSAGCIMKDVHLACLEGAREESVHLVRHFYKGEDIFLDMFEDEYRSMTMKPMNVEYLMMDASILLPPTGTPLTGIDFVKRLPC
GDVEKTRRAIRVFFMLRSLSLQLRGEPETQLPLTREEDLIKTDDVLDLNNSDLIACTVITKDGGMVQRFLAVDIYQMSLVEPDVSRLGWG
VVKFAGLLQDMQVTGVEDDSRALNITIHKPASSPHSKPFPILQATFIFSDHIRCIIAKQRLAKGRIQARRMKMQRIAALLDLPIQPTTEV

--------------------------------------------------------------
>65835_65835_2_PLA2G10-CLEC16A_PLA2G10_chr16_14787989_ENST00000438167_CLEC16A_chr16_11096930_ENST00000409790_length(transcript)=6127nt_BP=537nt
GGCCTTCCAAAGTGCTGGGATTACAGGCGTGAGTCACCGCGCCCGGCCAAATAAAATAAAATGTTAAAGCAAATTCAGGACTACCCCTCC
TCCAAGTCTTCTGTTCCCTTTGGGCGCCCAGGTGAGCGGGGGAGGGGCTGGGGGAGTAATAACATCAAAAGAGCGCCTTTTCCTCCCTTA
TTCCGAGGAGACTTCCCTGGGCCTGACTCCCGGTCCTGTCCCCAGCGCCCCGCGGCCTCTGGAGCCCCTTCAGTGACCAAGATACAGAGA
TCAGGACGCCTTTGCGCCGCCCCAGGTGCCCGCCCCTAGCTGGCTCTGCTTGGGCCGCGAGGGAAGGTGAGGTCGGGGGCGGAGCCGGGG
CGTGACAGCCGGGGTGTGTGTCCGCCGGGCTTGGTGCCTCCGGTGGCCCTGCAGCACCGTCCCACCTCTGCCACCCTCCGATGGGGCCGC
TACCTGTGTGCCTGCCAATCATGCTGCTCCTGCTACTGCCGTCGCTGCTGCTGCTGCTGCTTCTACCTGGCCCCGGGTCCGGCGAGGGCC
AAGCCCAGCATTCGGTGCTTCATTAAACCCACCGAGACACTCGAGCGGTCCCTTGAGATGAACAAGCACAAGGGCAAGAGGCGGGTGCAA
AAGAGACCCAACTACAAAAACGTTGGGGAAGAAGAAGATGAGGAGAAAGGGCCCACCGAGGATGCCCAAGAAGACGCCGAGAAGGCTAAA
GGTACAGAGGGTGGTTCAAAAGGCATCAAGACGAGTGGGGAGAGTGAAGAGATCGAGATGGTGATCATGGAGCGTAGCAAGCTCTCAGAG
CTGGCCGCCAGCACCTCCGTGCAGGAGCAGAACACCACGGACGAGGAGAAAAGCGCCGCCGCCACCTGCTCTGAGAGCACGCAATGGAGC
AGACCCTTCCTGGATATGGTGTACCACGCGCTGGACAGCCCGGATGATGATTACCATGCCCTGTTCGTGCTCTGCCTCCTCTATGCCATG
TCTCATAATAAAGGCATGGATCCTGAAAAATTAGAGCGAATCCAGCTCCCCGTGCCAAATGCGGCCGAGAAGACCACCTACAACCACCCG
CTAGCTGAAAGACTCATCAGGATCATGAACAACGCTGCCCAGCCAGATGGGAAGATCCGGCTGGCGACGCTGGAGCTGAGCTGCCTGCTT
CTGAAGCAGCAAGTCCTGATGAGTGCTGGCTGCATCATGAAGGACGTGCACCTGGCCTGCCTGGAGGGTGCGAGAGAAGAAAGTGTTCAC
CTTGTACGACATTTTTATAAGGGAGAAGACATTTTTTTGGACATGTTTGAAGATGAGTATAGGAGCATGACAATGAAGCCCATGAACGTG
GAATATCTCATGATGGACGCCTCCATCCTGCTGCCCCCAACAGGCACGCCACTGACGGGCATTGACTTCGTGAAGCGGCTGCCGTGTGGC
GATGTGGAGAAGACCCGGCGGGCCATCCGGGTGTTCTTCATGCTGCGTTCCCTGTCACTGCAATTGCGAGGGGAGCCTGAGACACAGTTG
CCGCTGACTCGGGAGGAGGACCTGATCAAGACTGATGATGTCCTGGATCTGAATAACAGCGACTTGATTGCATGTACAGTGATCACCAAG
GATGGCGGCATGGTCCAGCGATTCCTGGCTGTGGATATTTACCAGATGAGTTTGGTGGAGCCTGATGTGTCCAGGCTTGGCTGGGGAGTG
GTCAAGTTTGCAGGCCTATTGCAGGACATGCAGGTGACTGGCGTGGAGGACGACAGCCGTGCCCTGAACATCACCATCCACAAGCCTGCG
TCCAGCCCCCATTCCAAGCCCTTCCCCATCCTCCAGGCCACCTTCATCTTCTCAGACCACATCCGCTGCATCATCGCCAAGCAGCGCCTG
GCCAAAGGCCGCATCCAGGCAAGGCGCATGAAGATGCAGAGAATAGCTGCCCTCCTGGACCTCCCAATCCAGCCCACCACTGAAGTCCTG
GGGTTTGGACTCGGCTCCTCCACCTCCACTCAGCACCTGCCTTTCCGCTTCTACGACCAGGGGCGCCGGGGCAGCAGCGACCCCACAGTG
CAGCGCTCCGTGTTTGCATCGGTGGACAAGGTGCCAGGCTTCGCCGTGGCCCAGTGCATAAACCAGCACAGCTCCCCGTCCCTGTCCTCA
CAGTCGCCACCCTCCGCCAGCGGGAGCCCCAGCGGCAGCGGGAGCACCAGCCACTGCGACTCTGGAGGCACCAGCTCGTCCTCCACCCCC
TCCACAGCCCAGAGTCCAGCAGATGCCCCCATGAGTCCAGAACTGCCTAAGCCTCACCTTCCTGACCAGTTGGTAATCGTCAACGAAACG
GAAGCAGACTCTAAGCCCAGCAAGAACGTGGCCAGGAGCGCAGCCGTGGAGACAGCCAGCCTGTCCCCCAGCCTCGTCCCTGCCCGGCAG
CCCACCATTTCCCTGCTCTGCGAGGACACGGCTGACACGCTGAGCGTCGAATCGCTGACCCTTGTCCCCCCAGTTGACCCCCACAGCCTC
CGCAGCCTCACCGGCATGCCCCCGCTGTCCACGCCGGCTGCCGCCTGCACAGAGCCCGTGGGCGAAGAGGCTGCATGTGCTGAGCCTGTG
GGCACCGCTGAGGACTGAGTCAGTGCCGGGGCCTCCCTTTGTGTGTGTGGCCCCGCTGGTAGGGACCCCAGTGCCGCTGACTGGCAAGAC
ACACTGGGAGCACCCACCATTCTGTGCGGCCCCCAGCAGCCATCTCAACCACCTATCCCTGCGCTCCCTTGAATGGGAAGAAGCCCCACG
TTGTCCTTGAATTCCTTTTTCACTTTGCATCTCTTCACGTGCAGGCTGGGACCAGCGGAGACACCGCGGCGAATGCAGATGACTGCACCG
GCCACTCAGGGAGCTGCCTGGGCTCCGTGTCTCTGAGCCCCGGGTGGCAGGACCCACCGGCACCTCTTTCTTCCTCTGTCATATGGCTCC
TCTGTCACCAGCCCCAGTGTGCACAGAAGAATTGGACCAGGTCACTGTACGTAGAAATTTGTAGAAAAGCAGACTTAGATAAACATCTCC
TTTGGATATTTATTTCCGCTTTTGGCAGCAGGTGAACATTTATTTTTAAAACTTCTATTTAAAAGAAGTCCAAAAACATCAACACTAAGG
TTTGATGTCATGTGAAAAGTGTAATAATAACAGTTAAGATTTCATGATCATTTTCACTGGACCTTTCCTGATATTTTGTTTCAGAGTTCT
TAGTGTGGCTTTTTCCATTTATTTAAGTGATTCTTTGTTACTCACTAACTCTGCAAGCCTGTGGAATAATGAAGTACCTTCCTGGAAAGT
TTGGATTATTTTTTAAACAAAAACAAGGGAGATACATGTATTCTCAGGTACACACAGAGCTGAGAGGGCTGAATGGTTTTCTGCTATAGC
AGCCGAGAGGCCTCCCATCATGGAAAGATTTCTCCAGGAAAAGGAGGAATGTAGCCAGCTCCCCACTCAGGACGCTTCCTCATTTCTCTT
CACCAAAACCAAACAGAGACAGCTTCCAGCACCTTCTTCAGTGTTACCATCTCTAAGAAGGAACCAGTTGGGACCGTGAAGACTCCCGAC
CCTGTGGCCATGATGGAAATCAAAGGAAGACACCCTCTACGTCACCTGCCCTCGACTGTGTGTGCCCACATGTGCCGAGAGATGGCCCAG
AGCCAGTTCCCCTCCAGCTGCAAGGGCATGGTGTCCCCAGAGCTCTGAGTCTGTCACTCTCCCTCTGCTACTGCTGCTGATCTGAATATG
GAAACCCCATGGTTCCCTTCCCCATTCGGACTGGGTGTGTACAAGCAAGGACCCAGATGCATCAGACACAGCCCCCAAGATGTTCCTTTC
TACTCGGCCAGCTCGGGAGCCAGACACAGCACTCACAGCCCAGGCCGTGATCCACCCTCCCCAAGTCCACCAGGGCCAGCGGCCCCTCAC
CTCTCTGGTCACTGGTGAGACCTTCCACAACTTTCCTCCAGACCTGCCAGCAGATGTGCCCACCAGGGGCATTAGGTATCCGCCGGAGCC
TGGCCATAGGGTAGTCTCGGGAGCCGCGCTGAGATCTTTTGCCACCTGCATTTTAGAAGAACATGGTCTCTGTCTCCTCGGCCCAGCCAG
CTGTCCCGGCAAGGCCTGCCGAGGGCAGTTTTCAACCTCATGAAGGAAACACAGTCCTGCCAAGGAGGGGGAGTGGCGCCCATGGGGACA
GGCCTCAGTCCTTAGAAGCCCTCTGGGTAGCTGTGCCCACCCAGCCTTCATGGCTGCAGGTACAAGGACCTTTGCTTCCATAGAGAAAAC
GCACAGCTCAGAAAGGGGGCCACATGGGCAGAAACCCAAAGGAAGGACAAACCACGACCACCGTGGCCATCTGCAGAATCCCTGGAAGAG
AAGGAAGGCAGGGTGGAGCGGGGGGAAGACCATCATGGAGAGAAGGACCACAGCATCAGGAGACGGGACACGCCACACCCAGCAGGCAGC
CTGTGTGTTGCTTAATTTTTTAAGAGCAAGAGGGGTAGAGAGGATCAAGCTGGCCCTGGCTGGAGATGGCTAGCCCCTGAGACATGCACT
TCTGGTTTTGAAATGACTCTGTCTGTGGGGCAGCAGAAACTAGAGAAGGCAAGTGGCTGCCCCACCCCAAGGCGTGACCAGGAGGAACAG
CCTGCAGCTCACTCCATGCCACACGGGTGGGCCACCAGCCTGCTGTCAGAAGTCTCTGGGCTCCAACTGGTCTTGTAACCACTGAGCACT
GAAGGAGAGAGGTCTTGGTCAGGGCTGGACAGCATGCCCGGGAGGACCAGCAGAGGATTAAAGGTGACTGGGAGGACCAGCGGAGGATAA
AAGACACTGCTCAGGGCAGGGCTTCTACCCTGCATCCCTGGCCAAGAAAAGGGCAGTCCCCATGTGGGCTTGCAGGGTCACTCTCAGGGG
CCTCTTTCAGCTGGGGCTGGCAACTTGCGTCTGGGGGACACCTCCAGGTGTGTGGGGTGAGGATTTCCTATAACCAGGGCTCCCAGAAGC
TTTGCTTATGTAAGGAGGTCTGGGAGCCAGCCCATTGGAGGCCACCAGCCATTTTGGCTTCAAAGGACCCCACCTCACCCAGGTCTCAGC
GGCAGTGGGCACAGCTATGTCTTCAGGAGCTCCCGTCAAACCTCATAGCTGGGGCGCTCCCAGACAGGCCAGTCCAGACAGGACACGCTG
GGCCCCTGGCATCCAGAGGAAGAGCCAGGAGTGTGGGAAGGCCCACAGTGGGGGCTGTGGCTTCTGACACTCAGGTCATAGCCTCAGAGG
TCTGAGGTCAGCCCCCACAGACCCATCCGGCCCGCCCCCCAAGTCCCTGCAGAGAGCACTTAGAGTTATGGCCCAGGCCCTGGTCCACCC
TTCCCCTGTGCACCTCCGGCTGGGTTTGCCAAGTCAGGGAGCAGGGCTGGCCGCAGGAACTCCCAAACCTTGGCTTTGAATATTGTTGTG
GAGGTGTGCTCGTCCCTTTCTGGACGTGCAAGGTACCTGTCCCAGCAGGTCAGATGGGGCCAGCTGAGGCGCTCCCCCAGGCAGGAAGGG
CCAGCCTTCACCATCGCGTGGGATTGGGAGGAGGGGCCTCCGTGAGCAGCCCCTCCTCTGCCGCTGTCCCAGCCCAGTCCCTCTCCCGGA
GCCTTGGCAGCCTCCCACAACCCAGACACTTGCGTTCACAAGCAACCTAAGGGGCAGGTGAAGAAGCGCAGCCCTGCCAGACGCGCTAGA
TTCCTCTAAGGTCTCTGAGATGCACCGTTTTTTAAAAAGGCGTGGGGTGAACTGATTTTGATCTTCTTGTCTAGATGCAATAAATAAATC
TGAAGCATTTAATGTAGTCATCTTGACATTGGGCCTACACTGTACGAGTTCCTTATGTTTCCTTGAGCTAAAAATATGTAAATAATTTTT
GTCCCAGTGAGAACCGAGGGTTAGAAAACCTCGATGCCTCTGAGCCTCGGGACCGCTCTAGGGAAGTACCTGCTTTCGCCAGCATGACTC
ATGCTTCGTGGGTACTGAACACGAGGGTGGAAATGAAAACTGGAACTTCCTTGTAAATTTAAACTTGGCAATAAAAGAGAAAAAAAGTTA

>65835_65835_2_PLA2G10-CLEC16A_PLA2G10_chr16_14787989_ENST00000438167_CLEC16A_chr16_11096930_ENST00000409790_length(amino acids)=772AA_BP=71
MALLGPRGKVRSGAEPGRDSRGVCPPGLVPPVALQHRPTSATLRWGRYLCACQSCCSCYCRRCCCCCFYLAPGPARAKPSIRCFIKPTET
LERSLEMNKHKGKRRVQKRPNYKNVGEEEDEEKGPTEDAQEDAEKAKGTEGGSKGIKTSGESEEIEMVIMERSKLSELAASTSVQEQNTT
DEEKSAAATCSESTQWSRPFLDMVYHALDSPDDDYHALFVLCLLYAMSHNKGMDPEKLERIQLPVPNAAEKTTYNHPLAERLIRIMNNAA
QPDGKIRLATLELSCLLLKQQVLMSAGCIMKDVHLACLEGAREESVHLVRHFYKGEDIFLDMFEDEYRSMTMKPMNVEYLMMDASILLPP
TGTPLTGIDFVKRLPCGDVEKTRRAIRVFFMLRSLSLQLRGEPETQLPLTREEDLIKTDDVLDLNNSDLIACTVITKDGGMVQRFLAVDI
YQMSLVEPDVSRLGWGVVKFAGLLQDMQVTGVEDDSRALNITIHKPASSPHSKPFPILQATFIFSDHIRCIIAKQRLAKGRIQARRMKMQ
RIAALLDLPIQPTTEVLGFGLGSSTSTQHLPFRFYDQGRRGSSDPTVQRSVFASVDKVPGFAVAQCINQHSSPSLSSQSPPSASGSPSGS
GSTSHCDSGGTSSSSTPSTAQSPADAPMSPELPKPHLPDQLVIVNETEADSKPSKNVARSAAVETASLSPSLVPARQPTISLLCEDTADT

--------------------------------------------------------------
>65835_65835_3_PLA2G10-CLEC16A_PLA2G10_chr16_14787990_ENST00000438167_CLEC16A_chr16_11096931_ENST00000409552_length(transcript)=2257nt_BP=537nt
GGCCTTCCAAAGTGCTGGGATTACAGGCGTGAGTCACCGCGCCCGGCCAAATAAAATAAAATGTTAAAGCAAATTCAGGACTACCCCTCC
TCCAAGTCTTCTGTTCCCTTTGGGCGCCCAGGTGAGCGGGGGAGGGGCTGGGGGAGTAATAACATCAAAAGAGCGCCTTTTCCTCCCTTA
TTCCGAGGAGACTTCCCTGGGCCTGACTCCCGGTCCTGTCCCCAGCGCCCCGCGGCCTCTGGAGCCCCTTCAGTGACCAAGATACAGAGA
TCAGGACGCCTTTGCGCCGCCCCAGGTGCCCGCCCCTAGCTGGCTCTGCTTGGGCCGCGAGGGAAGGTGAGGTCGGGGGCGGAGCCGGGG
CGTGACAGCCGGGGTGTGTGTCCGCCGGGCTTGGTGCCTCCGGTGGCCCTGCAGCACCGTCCCACCTCTGCCACCCTCCGATGGGGCCGC
TACCTGTGTGCCTGCCAATCATGCTGCTCCTGCTACTGCCGTCGCTGCTGCTGCTGCTGCTTCTACCTGGCCCCGGGTCCGGCGAGGGCC
AAGCCCAGCATTCGGTGCTTCATTAAACCCACCGAGACACTCGAGCGGTCCCTTGAGATGAACAAGCACAAGGGCAAGAGGCGGGTGCAA
AAGAGACCCAACTACAAAAACGTTGGGGAAGAAGAAGATGAGGAGAAAGGGCCCACCGAGGATGCCCAAGAAGACGCCGAGAAGGCTAAA
GAGATCGAGATGGTGATCATGGAGCGTAGCAAGCTCTCAGAGCTGGCCGCCAGCACCTCCGTGCAGGAGCAGAACACCACGGACGAGGAG
AAAAGCGCCGCCGCCACCTGCTCTGAGAGCACGCAATGGAGCAGACCCTTCCTGGATATGGTGTACCACGCGCTGGACAGCCCGGATGAT
GATTACCATGCCCTGTTCGTGCTCTGCCTCCTCTATGCCATGTCTCATAATAAAGGCATGGATCCTGAAAAATTAGAGCGAATCCAGCTC
CCCGTGCCAAATGCGGCCGAGAAGACCACCTACAACCACCCGCTAGCTGAAAGACTCATCAGGATCATGAACAACGCTGCCCAGCCAGAT
GGGAAGATCCGGCTGGCGACGCTGGAGCTGAGCTGCCTGCTTCTGAAGCAGCAAGTCCTGATGAGTGCTGGCTGCATCATGAAGGACGTG
CACCTGGCCTGCCTGGAGGGTGCGAGAGAAGAAAGTGTTCACCTTGTACGACATTTTTATAAGGGAGAAGACATTTTTTTGGACATGTTT
GAAGATGAGTATAGGAGCATGACAATGAAGCCCATGAACGTGGAATATCTCATGATGGACGCCTCCATCCTGCTGCCCCCAACAGGCACG
CCACTGACGGGCATTGACTTCGTGAAGCGGCTGCCGTGTGGCGATGTGGAGAAGACCCGGCGGGCCATCCGGGTGTTCTTCATGCTGCGT
TCCCTGTCACTGCAATTGCGAGGGGAGCCTGAGACACAGTTGCCGCTGACTCGGGAGGAGGACCTGATCAAGACTGATGATGTCCTGGAT
CTGAATAACAGCGACTTGATTGCATGTACAGTGATCACCAAGGATGGCGGCATGGTCCAGCGATTCCTGGCTGTGGATATTTACCAGATG
AGTTTGGTGGAGCCTGATGTGTCCAGGCTTGGCTGGGGAGTGGTCAAGTTTGCAGGCCTATTGCAGGACATGCAGGTGACTGGCGTGGAG
GACGACAGCCGTGCCCTGAACATCACCATCCACAAGCCTGCGTCCAGCCCCCATTCCAAGCCCTTCCCCATCCTCCAGGCCACCTTCATC
TTCTCAGACCACATCCGCTGCATCATCGCCAAGCAGCGCCTGGCCAAAGGCCGCATCCAGGCAAGGCGCATGAAGATGCAGAGAATAGCT
GCCCTCCTGGACCTCCCAATCCAGCCCACCACTGAAGTCCTGGGGTTTGGACTCGGCTCCTCCACCTCCACTCAGCACCTGCCTTTCCGC
TTCTACGACCAGGGGCGCCGGGGCAGCAGCGACCCCACAGTGCAGCGCTCCGTGTTTGCATCGGTGGACAAGGTGCCAGGTGAGCCAGCC
CCCCGCCCTGCGCCACAGCTCGTTCATCATGGTGGGCGTTCAAGGTCTTTCTCTCTGTGGAGCCTGTGTGAGCTGCCCTTCCTCTCTCAG
AAGCCCCGTCGGCTGGCAGCACCAGCTTCTTAGAATTTGTCAAAGCACAGCGCAAGATTAAACACAGCCCCCAAAATAAATTTTGGCTTT

>65835_65835_3_PLA2G10-CLEC16A_PLA2G10_chr16_14787990_ENST00000438167_CLEC16A_chr16_11096931_ENST00000409552_length(amino acids)=627AA_BP=71
MALLGPRGKVRSGAEPGRDSRGVCPPGLVPPVALQHRPTSATLRWGRYLCACQSCCSCYCRRCCCCCFYLAPGPARAKPSIRCFIKPTET
LERSLEMNKHKGKRRVQKRPNYKNVGEEEDEEKGPTEDAQEDAEKAKEIEMVIMERSKLSELAASTSVQEQNTTDEEKSAAATCSESTQW
SRPFLDMVYHALDSPDDDYHALFVLCLLYAMSHNKGMDPEKLERIQLPVPNAAEKTTYNHPLAERLIRIMNNAAQPDGKIRLATLELSCL
LLKQQVLMSAGCIMKDVHLACLEGAREESVHLVRHFYKGEDIFLDMFEDEYRSMTMKPMNVEYLMMDASILLPPTGTPLTGIDFVKRLPC
GDVEKTRRAIRVFFMLRSLSLQLRGEPETQLPLTREEDLIKTDDVLDLNNSDLIACTVITKDGGMVQRFLAVDIYQMSLVEPDVSRLGWG
VVKFAGLLQDMQVTGVEDDSRALNITIHKPASSPHSKPFPILQATFIFSDHIRCIIAKQRLAKGRIQARRMKMQRIAALLDLPIQPTTEV

--------------------------------------------------------------
>65835_65835_4_PLA2G10-CLEC16A_PLA2G10_chr16_14787990_ENST00000438167_CLEC16A_chr16_11096931_ENST00000409790_length(transcript)=6127nt_BP=537nt
GGCCTTCCAAAGTGCTGGGATTACAGGCGTGAGTCACCGCGCCCGGCCAAATAAAATAAAATGTTAAAGCAAATTCAGGACTACCCCTCC
TCCAAGTCTTCTGTTCCCTTTGGGCGCCCAGGTGAGCGGGGGAGGGGCTGGGGGAGTAATAACATCAAAAGAGCGCCTTTTCCTCCCTTA
TTCCGAGGAGACTTCCCTGGGCCTGACTCCCGGTCCTGTCCCCAGCGCCCCGCGGCCTCTGGAGCCCCTTCAGTGACCAAGATACAGAGA
TCAGGACGCCTTTGCGCCGCCCCAGGTGCCCGCCCCTAGCTGGCTCTGCTTGGGCCGCGAGGGAAGGTGAGGTCGGGGGCGGAGCCGGGG
CGTGACAGCCGGGGTGTGTGTCCGCCGGGCTTGGTGCCTCCGGTGGCCCTGCAGCACCGTCCCACCTCTGCCACCCTCCGATGGGGCCGC
TACCTGTGTGCCTGCCAATCATGCTGCTCCTGCTACTGCCGTCGCTGCTGCTGCTGCTGCTTCTACCTGGCCCCGGGTCCGGCGAGGGCC
AAGCCCAGCATTCGGTGCTTCATTAAACCCACCGAGACACTCGAGCGGTCCCTTGAGATGAACAAGCACAAGGGCAAGAGGCGGGTGCAA
AAGAGACCCAACTACAAAAACGTTGGGGAAGAAGAAGATGAGGAGAAAGGGCCCACCGAGGATGCCCAAGAAGACGCCGAGAAGGCTAAA
GGTACAGAGGGTGGTTCAAAAGGCATCAAGACGAGTGGGGAGAGTGAAGAGATCGAGATGGTGATCATGGAGCGTAGCAAGCTCTCAGAG
CTGGCCGCCAGCACCTCCGTGCAGGAGCAGAACACCACGGACGAGGAGAAAAGCGCCGCCGCCACCTGCTCTGAGAGCACGCAATGGAGC
AGACCCTTCCTGGATATGGTGTACCACGCGCTGGACAGCCCGGATGATGATTACCATGCCCTGTTCGTGCTCTGCCTCCTCTATGCCATG
TCTCATAATAAAGGCATGGATCCTGAAAAATTAGAGCGAATCCAGCTCCCCGTGCCAAATGCGGCCGAGAAGACCACCTACAACCACCCG
CTAGCTGAAAGACTCATCAGGATCATGAACAACGCTGCCCAGCCAGATGGGAAGATCCGGCTGGCGACGCTGGAGCTGAGCTGCCTGCTT
CTGAAGCAGCAAGTCCTGATGAGTGCTGGCTGCATCATGAAGGACGTGCACCTGGCCTGCCTGGAGGGTGCGAGAGAAGAAAGTGTTCAC
CTTGTACGACATTTTTATAAGGGAGAAGACATTTTTTTGGACATGTTTGAAGATGAGTATAGGAGCATGACAATGAAGCCCATGAACGTG
GAATATCTCATGATGGACGCCTCCATCCTGCTGCCCCCAACAGGCACGCCACTGACGGGCATTGACTTCGTGAAGCGGCTGCCGTGTGGC
GATGTGGAGAAGACCCGGCGGGCCATCCGGGTGTTCTTCATGCTGCGTTCCCTGTCACTGCAATTGCGAGGGGAGCCTGAGACACAGTTG
CCGCTGACTCGGGAGGAGGACCTGATCAAGACTGATGATGTCCTGGATCTGAATAACAGCGACTTGATTGCATGTACAGTGATCACCAAG
GATGGCGGCATGGTCCAGCGATTCCTGGCTGTGGATATTTACCAGATGAGTTTGGTGGAGCCTGATGTGTCCAGGCTTGGCTGGGGAGTG
GTCAAGTTTGCAGGCCTATTGCAGGACATGCAGGTGACTGGCGTGGAGGACGACAGCCGTGCCCTGAACATCACCATCCACAAGCCTGCG
TCCAGCCCCCATTCCAAGCCCTTCCCCATCCTCCAGGCCACCTTCATCTTCTCAGACCACATCCGCTGCATCATCGCCAAGCAGCGCCTG
GCCAAAGGCCGCATCCAGGCAAGGCGCATGAAGATGCAGAGAATAGCTGCCCTCCTGGACCTCCCAATCCAGCCCACCACTGAAGTCCTG
GGGTTTGGACTCGGCTCCTCCACCTCCACTCAGCACCTGCCTTTCCGCTTCTACGACCAGGGGCGCCGGGGCAGCAGCGACCCCACAGTG
CAGCGCTCCGTGTTTGCATCGGTGGACAAGGTGCCAGGCTTCGCCGTGGCCCAGTGCATAAACCAGCACAGCTCCCCGTCCCTGTCCTCA
CAGTCGCCACCCTCCGCCAGCGGGAGCCCCAGCGGCAGCGGGAGCACCAGCCACTGCGACTCTGGAGGCACCAGCTCGTCCTCCACCCCC
TCCACAGCCCAGAGTCCAGCAGATGCCCCCATGAGTCCAGAACTGCCTAAGCCTCACCTTCCTGACCAGTTGGTAATCGTCAACGAAACG
GAAGCAGACTCTAAGCCCAGCAAGAACGTGGCCAGGAGCGCAGCCGTGGAGACAGCCAGCCTGTCCCCCAGCCTCGTCCCTGCCCGGCAG
CCCACCATTTCCCTGCTCTGCGAGGACACGGCTGACACGCTGAGCGTCGAATCGCTGACCCTTGTCCCCCCAGTTGACCCCCACAGCCTC
CGCAGCCTCACCGGCATGCCCCCGCTGTCCACGCCGGCTGCCGCCTGCACAGAGCCCGTGGGCGAAGAGGCTGCATGTGCTGAGCCTGTG
GGCACCGCTGAGGACTGAGTCAGTGCCGGGGCCTCCCTTTGTGTGTGTGGCCCCGCTGGTAGGGACCCCAGTGCCGCTGACTGGCAAGAC
ACACTGGGAGCACCCACCATTCTGTGCGGCCCCCAGCAGCCATCTCAACCACCTATCCCTGCGCTCCCTTGAATGGGAAGAAGCCCCACG
TTGTCCTTGAATTCCTTTTTCACTTTGCATCTCTTCACGTGCAGGCTGGGACCAGCGGAGACACCGCGGCGAATGCAGATGACTGCACCG
GCCACTCAGGGAGCTGCCTGGGCTCCGTGTCTCTGAGCCCCGGGTGGCAGGACCCACCGGCACCTCTTTCTTCCTCTGTCATATGGCTCC
TCTGTCACCAGCCCCAGTGTGCACAGAAGAATTGGACCAGGTCACTGTACGTAGAAATTTGTAGAAAAGCAGACTTAGATAAACATCTCC
TTTGGATATTTATTTCCGCTTTTGGCAGCAGGTGAACATTTATTTTTAAAACTTCTATTTAAAAGAAGTCCAAAAACATCAACACTAAGG
TTTGATGTCATGTGAAAAGTGTAATAATAACAGTTAAGATTTCATGATCATTTTCACTGGACCTTTCCTGATATTTTGTTTCAGAGTTCT
TAGTGTGGCTTTTTCCATTTATTTAAGTGATTCTTTGTTACTCACTAACTCTGCAAGCCTGTGGAATAATGAAGTACCTTCCTGGAAAGT
TTGGATTATTTTTTAAACAAAAACAAGGGAGATACATGTATTCTCAGGTACACACAGAGCTGAGAGGGCTGAATGGTTTTCTGCTATAGC
AGCCGAGAGGCCTCCCATCATGGAAAGATTTCTCCAGGAAAAGGAGGAATGTAGCCAGCTCCCCACTCAGGACGCTTCCTCATTTCTCTT
CACCAAAACCAAACAGAGACAGCTTCCAGCACCTTCTTCAGTGTTACCATCTCTAAGAAGGAACCAGTTGGGACCGTGAAGACTCCCGAC
CCTGTGGCCATGATGGAAATCAAAGGAAGACACCCTCTACGTCACCTGCCCTCGACTGTGTGTGCCCACATGTGCCGAGAGATGGCCCAG
AGCCAGTTCCCCTCCAGCTGCAAGGGCATGGTGTCCCCAGAGCTCTGAGTCTGTCACTCTCCCTCTGCTACTGCTGCTGATCTGAATATG
GAAACCCCATGGTTCCCTTCCCCATTCGGACTGGGTGTGTACAAGCAAGGACCCAGATGCATCAGACACAGCCCCCAAGATGTTCCTTTC
TACTCGGCCAGCTCGGGAGCCAGACACAGCACTCACAGCCCAGGCCGTGATCCACCCTCCCCAAGTCCACCAGGGCCAGCGGCCCCTCAC
CTCTCTGGTCACTGGTGAGACCTTCCACAACTTTCCTCCAGACCTGCCAGCAGATGTGCCCACCAGGGGCATTAGGTATCCGCCGGAGCC
TGGCCATAGGGTAGTCTCGGGAGCCGCGCTGAGATCTTTTGCCACCTGCATTTTAGAAGAACATGGTCTCTGTCTCCTCGGCCCAGCCAG
CTGTCCCGGCAAGGCCTGCCGAGGGCAGTTTTCAACCTCATGAAGGAAACACAGTCCTGCCAAGGAGGGGGAGTGGCGCCCATGGGGACA
GGCCTCAGTCCTTAGAAGCCCTCTGGGTAGCTGTGCCCACCCAGCCTTCATGGCTGCAGGTACAAGGACCTTTGCTTCCATAGAGAAAAC
GCACAGCTCAGAAAGGGGGCCACATGGGCAGAAACCCAAAGGAAGGACAAACCACGACCACCGTGGCCATCTGCAGAATCCCTGGAAGAG
AAGGAAGGCAGGGTGGAGCGGGGGGAAGACCATCATGGAGAGAAGGACCACAGCATCAGGAGACGGGACACGCCACACCCAGCAGGCAGC
CTGTGTGTTGCTTAATTTTTTAAGAGCAAGAGGGGTAGAGAGGATCAAGCTGGCCCTGGCTGGAGATGGCTAGCCCCTGAGACATGCACT
TCTGGTTTTGAAATGACTCTGTCTGTGGGGCAGCAGAAACTAGAGAAGGCAAGTGGCTGCCCCACCCCAAGGCGTGACCAGGAGGAACAG
CCTGCAGCTCACTCCATGCCACACGGGTGGGCCACCAGCCTGCTGTCAGAAGTCTCTGGGCTCCAACTGGTCTTGTAACCACTGAGCACT
GAAGGAGAGAGGTCTTGGTCAGGGCTGGACAGCATGCCCGGGAGGACCAGCAGAGGATTAAAGGTGACTGGGAGGACCAGCGGAGGATAA
AAGACACTGCTCAGGGCAGGGCTTCTACCCTGCATCCCTGGCCAAGAAAAGGGCAGTCCCCATGTGGGCTTGCAGGGTCACTCTCAGGGG
CCTCTTTCAGCTGGGGCTGGCAACTTGCGTCTGGGGGACACCTCCAGGTGTGTGGGGTGAGGATTTCCTATAACCAGGGCTCCCAGAAGC
TTTGCTTATGTAAGGAGGTCTGGGAGCCAGCCCATTGGAGGCCACCAGCCATTTTGGCTTCAAAGGACCCCACCTCACCCAGGTCTCAGC
GGCAGTGGGCACAGCTATGTCTTCAGGAGCTCCCGTCAAACCTCATAGCTGGGGCGCTCCCAGACAGGCCAGTCCAGACAGGACACGCTG
GGCCCCTGGCATCCAGAGGAAGAGCCAGGAGTGTGGGAAGGCCCACAGTGGGGGCTGTGGCTTCTGACACTCAGGTCATAGCCTCAGAGG
TCTGAGGTCAGCCCCCACAGACCCATCCGGCCCGCCCCCCAAGTCCCTGCAGAGAGCACTTAGAGTTATGGCCCAGGCCCTGGTCCACCC
TTCCCCTGTGCACCTCCGGCTGGGTTTGCCAAGTCAGGGAGCAGGGCTGGCCGCAGGAACTCCCAAACCTTGGCTTTGAATATTGTTGTG
GAGGTGTGCTCGTCCCTTTCTGGACGTGCAAGGTACCTGTCCCAGCAGGTCAGATGGGGCCAGCTGAGGCGCTCCCCCAGGCAGGAAGGG
CCAGCCTTCACCATCGCGTGGGATTGGGAGGAGGGGCCTCCGTGAGCAGCCCCTCCTCTGCCGCTGTCCCAGCCCAGTCCCTCTCCCGGA
GCCTTGGCAGCCTCCCACAACCCAGACACTTGCGTTCACAAGCAACCTAAGGGGCAGGTGAAGAAGCGCAGCCCTGCCAGACGCGCTAGA
TTCCTCTAAGGTCTCTGAGATGCACCGTTTTTTAAAAAGGCGTGGGGTGAACTGATTTTGATCTTCTTGTCTAGATGCAATAAATAAATC
TGAAGCATTTAATGTAGTCATCTTGACATTGGGCCTACACTGTACGAGTTCCTTATGTTTCCTTGAGCTAAAAATATGTAAATAATTTTT
GTCCCAGTGAGAACCGAGGGTTAGAAAACCTCGATGCCTCTGAGCCTCGGGACCGCTCTAGGGAAGTACCTGCTTTCGCCAGCATGACTC
ATGCTTCGTGGGTACTGAACACGAGGGTGGAAATGAAAACTGGAACTTCCTTGTAAATTTAAACTTGGCAATAAAAGAGAAAAAAAGTTA

>65835_65835_4_PLA2G10-CLEC16A_PLA2G10_chr16_14787990_ENST00000438167_CLEC16A_chr16_11096931_ENST00000409790_length(amino acids)=772AA_BP=71
MALLGPRGKVRSGAEPGRDSRGVCPPGLVPPVALQHRPTSATLRWGRYLCACQSCCSCYCRRCCCCCFYLAPGPARAKPSIRCFIKPTET
LERSLEMNKHKGKRRVQKRPNYKNVGEEEDEEKGPTEDAQEDAEKAKGTEGGSKGIKTSGESEEIEMVIMERSKLSELAASTSVQEQNTT
DEEKSAAATCSESTQWSRPFLDMVYHALDSPDDDYHALFVLCLLYAMSHNKGMDPEKLERIQLPVPNAAEKTTYNHPLAERLIRIMNNAA
QPDGKIRLATLELSCLLLKQQVLMSAGCIMKDVHLACLEGAREESVHLVRHFYKGEDIFLDMFEDEYRSMTMKPMNVEYLMMDASILLPP
TGTPLTGIDFVKRLPCGDVEKTRRAIRVFFMLRSLSLQLRGEPETQLPLTREEDLIKTDDVLDLNNSDLIACTVITKDGGMVQRFLAVDI
YQMSLVEPDVSRLGWGVVKFAGLLQDMQVTGVEDDSRALNITIHKPASSPHSKPFPILQATFIFSDHIRCIIAKQRLAKGRIQARRMKMQ
RIAALLDLPIQPTTEVLGFGLGSSTSTQHLPFRFYDQGRRGSSDPTVQRSVFASVDKVPGFAVAQCINQHSSPSLSSQSPPSASGSPSGS
GSTSHCDSGGTSSSSTPSTAQSPADAPMSPELPKPHLPDQLVIVNETEADSKPSKNVARSAAVETASLSPSLVPARQPTISLLCEDTADT

--------------------------------------------------------------

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Fusion Gene PPI Analysis for PLA2G10-CLEC16A


check button Go to ChiPPI (Chimeric Protein-Protein interactions) to see the chimeric PPI interaction in

ChiPPI page.


check button Protein-protein interactors with each fusion partner protein in wild-type (BIOGRID-3.4.160)
HgeneHgene's interactorsTgeneTgene's interactors


check button - Retained PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenStill interaction with


check button - Lost PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


check button - Retained PPIs, but lost function due to frame-shift fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


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Related Drugs for PLA2G10-CLEC16A


check button Drugs targeting genes involved in this fusion gene.
(DrugBank Version 5.1.8 2021-05-08)
PartnerGeneUniProtAccDrugBank IDDrug nameDrug activityDrug typeDrug status

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Related Diseases for PLA2G10-CLEC16A


check button Diseases associated with fusion partners.
(DisGeNet 4.0)
PartnerGeneDisease IDDisease name# pubmedsSource