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 | Fusion Gene Summary |
| Fusion Gene ORF analysis |
| Fusion Genomic Features |
| Fusion Protein Features |
| Fusion Gene Sequence |
| Fusion Gene PPI analysis |
| Related Drugs |
| Related Diseases |
Fusion gene:PLCB4-RASA3 (FusionGDB2 ID:66002) |
Fusion Gene Summary for PLCB4-RASA3 |
 Fusion gene summary |
| Fusion gene information | Fusion gene name: PLCB4-RASA3 | Fusion gene ID: 66002 | Hgene | Tgene | Gene symbol | PLCB4 | RASA3 | Gene ID | 5332 | 22821 |
| Gene name | phospholipase C beta 4 | RAS p21 protein activator 3 | |
| Synonyms | ARCND2|PI-PLC | GAP1IP4BP|GAPIII | |
| Cytomap | 20p12.3-p12.2 | 13q34 | |
| Type of gene | protein-coding | protein-coding | |
| Description | 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-41-phosphatidyl-D-myo-inositol-4,5-bisphosphatePLC-beta-4dJ1119D9.2 (Phopholipase C, beta 4 (1-Phosphatidylinositol-4,5-Bisphosphate Phosphodiesterase Beta 4))inositoltrisphosphohydrolase | ras GTPase-activating protein 3GTPase activating protein IIIGTPase-activating protein 1 family, inositol 1,3,4,5-tetrakisphosphate-binding proteinIns(1,3,4,5)P4-binding proteinins P4-binding protein | |
| Modification date | 20200320 | 20200313 | |
| UniProtAcc | . | . | |
| Ensembl transtripts involved in fusion gene | ENST00000492632, ENST00000278655, ENST00000334005, ENST00000378473, ENST00000378493, ENST00000378501, ENST00000414679, | ENST00000334062, ENST00000389544, ENST00000542651, | |
| Fusion gene scores | * DoF score | 10 X 10 X 6=600 | 6 X 6 X 5=180 |
| # samples | 10 | 6 | |
| ** MAII score | log2(10/600*10)=-2.58496250072116 possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs). DoF>8 and MAII<0 | log2(6/180*10)=-1.58496250072116 possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs). DoF>8 and MAII<0 | |
| Context | PubMed: PLCB4 [Title/Abstract] AND RASA3 [Title/Abstract] AND fusion [Title/Abstract] | ||
| Most frequent breakpoint | PLCB4(9424890)-RASA3(114762215), # samples:3 | ||
| Anticipated loss of major functional domain due to fusion event. | |||
| * DoF score (Degree of Frequency) = # partners X # break points X # cancer types ** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10) |
| Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez |
| Partner | Gene | GO ID | GO term | PubMed ID |
| Fusion gene breakpoints across PLCB4 (5'-gene) * Click on the image to open the UCSC genome browser with custom track showing this image in a new window. |
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| Fusion gene breakpoints across RASA3 (3'-gene) * Click on the image to open the UCSC genome browser with custom track showing this image in a new window. |
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| Fusion gene information from two resources (ChiTars 5.0 and ChimerDB 4.0) * All genome coordinats were lifted-over on hg19. * Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser. |
| Source | Disease | Sample | Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand |
| ChimerDB4 | READ | TCGA-G5-6641-01A | PLCB4 | chr20 | 9424890 | - | RASA3 | chr13 | 114762215 | - |
| ChimerDB4 | READ | TCGA-G5-6641-01A | PLCB4 | chr20 | 9424890 | + | RASA3 | chr13 | 114762215 | - |
| ChimerDB4 | READ | TCGA-G5-6641 | PLCB4 | chr20 | 9424890 | + | RASA3 | chr13 | 114762215 | - |
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Fusion Gene ORF analysis for PLCB4-RASA3 |
| Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure. * Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser. |
| ORF | Henst | Tenst | Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand |
| 3UTR-3CDS | ENST00000492632 | ENST00000334062 | PLCB4 | chr20 | 9424890 | + | RASA3 | chr13 | 114762215 | - |
| 3UTR-3CDS | ENST00000492632 | ENST00000389544 | PLCB4 | chr20 | 9424890 | + | RASA3 | chr13 | 114762215 | - |
| 3UTR-intron | ENST00000492632 | ENST00000542651 | PLCB4 | chr20 | 9424890 | + | RASA3 | chr13 | 114762215 | - |
| 5CDS-intron | ENST00000278655 | ENST00000542651 | PLCB4 | chr20 | 9424890 | + | RASA3 | chr13 | 114762215 | - |
| 5CDS-intron | ENST00000334005 | ENST00000542651 | PLCB4 | chr20 | 9424890 | + | RASA3 | chr13 | 114762215 | - |
| 5CDS-intron | ENST00000378473 | ENST00000542651 | PLCB4 | chr20 | 9424890 | + | RASA3 | chr13 | 114762215 | - |
| 5CDS-intron | ENST00000378493 | ENST00000542651 | PLCB4 | chr20 | 9424890 | + | RASA3 | chr13 | 114762215 | - |
| 5CDS-intron | ENST00000378501 | ENST00000542651 | PLCB4 | chr20 | 9424890 | + | RASA3 | chr13 | 114762215 | - |
| 5CDS-intron | ENST00000414679 | ENST00000542651 | PLCB4 | chr20 | 9424890 | + | RASA3 | chr13 | 114762215 | - |
| In-frame | ENST00000278655 | ENST00000334062 | PLCB4 | chr20 | 9424890 | + | RASA3 | chr13 | 114762215 | - |
| In-frame | ENST00000278655 | ENST00000389544 | PLCB4 | chr20 | 9424890 | + | RASA3 | chr13 | 114762215 | - |
| In-frame | ENST00000334005 | ENST00000334062 | PLCB4 | chr20 | 9424890 | + | RASA3 | chr13 | 114762215 | - |
| In-frame | ENST00000334005 | ENST00000389544 | PLCB4 | chr20 | 9424890 | + | RASA3 | chr13 | 114762215 | - |
| In-frame | ENST00000378473 | ENST00000334062 | PLCB4 | chr20 | 9424890 | + | RASA3 | chr13 | 114762215 | - |
| In-frame | ENST00000378473 | ENST00000389544 | PLCB4 | chr20 | 9424890 | + | RASA3 | chr13 | 114762215 | - |
| In-frame | ENST00000378493 | ENST00000334062 | PLCB4 | chr20 | 9424890 | + | RASA3 | chr13 | 114762215 | - |
| In-frame | ENST00000378493 | ENST00000389544 | PLCB4 | chr20 | 9424890 | + | RASA3 | chr13 | 114762215 | - |
| In-frame | ENST00000378501 | ENST00000334062 | PLCB4 | chr20 | 9424890 | + | RASA3 | chr13 | 114762215 | - |
| In-frame | ENST00000378501 | ENST00000389544 | PLCB4 | chr20 | 9424890 | + | RASA3 | chr13 | 114762215 | - |
| In-frame | ENST00000414679 | ENST00000334062 | PLCB4 | chr20 | 9424890 | + | RASA3 | chr13 | 114762215 | - |
| In-frame | ENST00000414679 | ENST00000389544 | PLCB4 | chr20 | 9424890 | + | RASA3 | chr13 | 114762215 | - |
| ORFfinder result based on the fusion transcript sequence of in-frame fusion genes. |
| Henst | Tenst | Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand | Seq length (transcript) | BP loci (transcript) | Predicted start (transcript) | Predicted stop (transcript) | Seq length (amino acids) |
| ENST00000334005 | PLCB4 | chr20 | 9424890 | + | ENST00000334062 | RASA3 | chr13 | 114762215 | - | 5212 | 3075 | 192 | 3647 | 1151 |
| ENST00000334005 | PLCB4 | chr20 | 9424890 | + | ENST00000389544 | RASA3 | chr13 | 114762215 | - | 3968 | 3075 | 192 | 3647 | 1151 |
| ENST00000378473 | PLCB4 | chr20 | 9424890 | + | ENST00000334062 | RASA3 | chr13 | 114762215 | - | 5248 | 3111 | 192 | 3683 | 1163 |
| ENST00000378473 | PLCB4 | chr20 | 9424890 | + | ENST00000389544 | RASA3 | chr13 | 114762215 | - | 4004 | 3111 | 192 | 3683 | 1163 |
| ENST00000278655 | PLCB4 | chr20 | 9424890 | + | ENST00000334062 | RASA3 | chr13 | 114762215 | - | 5059 | 2922 | 39 | 3494 | 1151 |
| ENST00000278655 | PLCB4 | chr20 | 9424890 | + | ENST00000389544 | RASA3 | chr13 | 114762215 | - | 3815 | 2922 | 39 | 3494 | 1151 |
| ENST00000414679 | PLCB4 | chr20 | 9424890 | + | ENST00000334062 | RASA3 | chr13 | 114762215 | - | 5032 | 2895 | 3 | 3467 | 1154 |
| ENST00000414679 | PLCB4 | chr20 | 9424890 | + | ENST00000389544 | RASA3 | chr13 | 114762215 | - | 3788 | 2895 | 3 | 3467 | 1154 |
| ENST00000378501 | PLCB4 | chr20 | 9424890 | + | ENST00000334062 | RASA3 | chr13 | 114762215 | - | 4996 | 2859 | 3 | 3431 | 1142 |
| ENST00000378501 | PLCB4 | chr20 | 9424890 | + | ENST00000389544 | RASA3 | chr13 | 114762215 | - | 3752 | 2859 | 3 | 3431 | 1142 |
| ENST00000378493 | PLCB4 | chr20 | 9424890 | + | ENST00000334062 | RASA3 | chr13 | 114762215 | - | 4996 | 2859 | 3 | 3431 | 1142 |
| ENST00000378493 | PLCB4 | chr20 | 9424890 | + | ENST00000389544 | RASA3 | chr13 | 114762215 | - | 3752 | 2859 | 3 | 3431 | 1142 |
| DeepORF prediction of the coding potential based on the fusion transcript sequence of in-frame fusion genes. DeepORF is a coding potential classifier based on convolutional neural network by comparing the real Ribo-seq data. If the no-coding score < 0.5 and coding score > 0.5, then the in-frame fusion transcript is predicted as being likely translated. |
| Henst | Tenst | Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand | No-coding score | Coding score |
| ENST00000334005 | ENST00000334062 | PLCB4 | chr20 | 9424890 | + | RASA3 | chr13 | 114762215 | - | 0.000825152 | 0.9991748 |
| ENST00000334005 | ENST00000389544 | PLCB4 | chr20 | 9424890 | + | RASA3 | chr13 | 114762215 | - | 0.001751294 | 0.9982487 |
| ENST00000378473 | ENST00000334062 | PLCB4 | chr20 | 9424890 | + | RASA3 | chr13 | 114762215 | - | 0.000900475 | 0.9990995 |
| ENST00000378473 | ENST00000389544 | PLCB4 | chr20 | 9424890 | + | RASA3 | chr13 | 114762215 | - | 0.001931911 | 0.99806815 |
| ENST00000278655 | ENST00000334062 | PLCB4 | chr20 | 9424890 | + | RASA3 | chr13 | 114762215 | - | 0.000731018 | 0.99926895 |
| ENST00000278655 | ENST00000389544 | PLCB4 | chr20 | 9424890 | + | RASA3 | chr13 | 114762215 | - | 0.001569548 | 0.99843043 |
| ENST00000414679 | ENST00000334062 | PLCB4 | chr20 | 9424890 | + | RASA3 | chr13 | 114762215 | - | 0.000761538 | 0.9992385 |
| ENST00000414679 | ENST00000389544 | PLCB4 | chr20 | 9424890 | + | RASA3 | chr13 | 114762215 | - | 0.001675978 | 0.998324 |
| ENST00000378501 | ENST00000334062 | PLCB4 | chr20 | 9424890 | + | RASA3 | chr13 | 114762215 | - | 0.000692372 | 0.99930763 |
| ENST00000378501 | ENST00000389544 | PLCB4 | chr20 | 9424890 | + | RASA3 | chr13 | 114762215 | - | 0.00152209 | 0.9984779 |
| ENST00000378493 | ENST00000334062 | PLCB4 | chr20 | 9424890 | + | RASA3 | chr13 | 114762215 | - | 0.000692372 | 0.99930763 |
| ENST00000378493 | ENST00000389544 | PLCB4 | chr20 | 9424890 | + | RASA3 | chr13 | 114762215 | - | 0.00152209 | 0.9984779 |
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Fusion Genomic Features for PLCB4-RASA3 |
| FusionAI prediction of the potential fusion gene breakpoint based on the pre-mature RNA sequence context (+/- 5kb of individual partner genes, total 20kb length sequence). FusionAI is a fusion gene breakpoint classifier based on convolutional neural network by comparing the fusion positive and negative sequence context of ~ 20K fusion gene data. From here, we can have the relative potentency of the 20K genomic sequence how individual sequnce will be likely used as the gene fusion breakpoints. |
| Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand | 1-p | p (fusion gene breakpoint) |
| Distribution of 44 human genomic features loci across 20kb length fusion breakpoint regions. We integrated a total of 44 different types of human genomic feature loci information across five big categories including virus integration sites, repeats, structural variants, chromatin states, and gene expression regulation. More details are in help page. |
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| Distribution of 44 human genomic features loci across 20kb length fusion breakpoint regions that are ovelapped with the top 1% feature importance score regions. More details are in help page. |
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Fusion Protein Features for PLCB4-RASA3 |
| Four levels of functional features of fusion genes Go to FGviewer search page for the most frequent breakpoint (https://ccsmweb.uth.edu/FGviewer/chr20:9424890/chr13:114762215) - FGviewer provides the online visualization of the retention search of the protein functional features across DNA, RNA, protein, and pathological levels. - How to search 1. Put your fusion gene symbol. 2. Press the tab key until there will be shown the breakpoint information filled. 4. Go down and press 'Search' tab twice. 4. Go down to have the hyperlink of the search result. 5. Click the hyperlink. 6. See the FGviewer result for your fusion gene. |
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| Main function of each fusion partner protein. (from UniProt) |
| Hgene | Tgene |
| . | . |
| FUNCTION: Transcriptional activator which is required for calcium-dependent dendritic growth and branching in cortical neurons. Recruits CREB-binding protein (CREBBP) to nuclear bodies. Component of the CREST-BRG1 complex, a multiprotein complex that regulates promoter activation by orchestrating a calcium-dependent release of a repressor complex and a recruitment of an activator complex. In resting neurons, transcription of the c-FOS promoter is inhibited by BRG1-dependent recruitment of a phospho-RB1-HDAC1 repressor complex. Upon calcium influx, RB1 is dephosphorylated by calcineurin, which leads to release of the repressor complex. At the same time, there is increased recruitment of CREBBP to the promoter by a CREST-dependent mechanism, which leads to transcriptional activation. The CREST-BRG1 complex also binds to the NR2B promoter, and activity-dependent induction of NR2B expression involves a release of HDAC1 and recruitment of CREBBP (By similarity). {ECO:0000250}. | FUNCTION: Transcriptional activator which is required for calcium-dependent dendritic growth and branching in cortical neurons. Recruits CREB-binding protein (CREBBP) to nuclear bodies. Component of the CREST-BRG1 complex, a multiprotein complex that regulates promoter activation by orchestrating a calcium-dependent release of a repressor complex and a recruitment of an activator complex. In resting neurons, transcription of the c-FOS promoter is inhibited by BRG1-dependent recruitment of a phospho-RB1-HDAC1 repressor complex. Upon calcium influx, RB1 is dephosphorylated by calcineurin, which leads to release of the repressor complex. At the same time, there is increased recruitment of CREBBP to the promoter by a CREST-dependent mechanism, which leads to transcriptional activation. The CREST-BRG1 complex also binds to the NR2B promoter, and activity-dependent induction of NR2B expression involves a release of HDAC1 and recruitment of CREBBP (By similarity). {ECO:0000250}. |
| Retention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at * Minus value of BPloci means that the break pointn is located before the CDS. |
| - In-frame and retained protein feature among the 13 regional features. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Protein feature | Protein feature note |
| Hgene | PLCB4 | chr20:9424890 | chr13:114762215 | ENST00000278655 | + | 29 | 36 | 313_463 | 948 | 1176.0 | Domain | PI-PLC X-box |
| Hgene | PLCB4 | chr20:9424890 | chr13:114762215 | ENST00000278655 | + | 29 | 36 | 565_681 | 948 | 1176.0 | Domain | PI-PLC Y-box |
| Hgene | PLCB4 | chr20:9424890 | chr13:114762215 | ENST00000278655 | + | 29 | 36 | 684_809 | 948 | 1176.0 | Domain | C2 |
| Hgene | PLCB4 | chr20:9424890 | chr13:114762215 | ENST00000334005 | + | 30 | 38 | 313_463 | 948 | 1195.0 | Domain | PI-PLC X-box |
| Hgene | PLCB4 | chr20:9424890 | chr13:114762215 | ENST00000334005 | + | 30 | 38 | 565_681 | 948 | 1195.0 | Domain | PI-PLC Y-box |
| Hgene | PLCB4 | chr20:9424890 | chr13:114762215 | ENST00000334005 | + | 30 | 38 | 684_809 | 948 | 1195.0 | Domain | C2 |
| Hgene | PLCB4 | chr20:9424890 | chr13:114762215 | ENST00000378493 | + | 28 | 35 | 313_463 | 948 | 1176.0 | Domain | PI-PLC X-box |
| Hgene | PLCB4 | chr20:9424890 | chr13:114762215 | ENST00000378493 | + | 28 | 35 | 565_681 | 948 | 1176.0 | Domain | PI-PLC Y-box |
| Hgene | PLCB4 | chr20:9424890 | chr13:114762215 | ENST00000378493 | + | 28 | 35 | 684_809 | 948 | 1176.0 | Domain | C2 |
| Hgene | PLCB4 | chr20:9424890 | chr13:114762215 | ENST00000378501 | + | 28 | 36 | 313_463 | 948 | 1195.0 | Domain | PI-PLC X-box |
| Hgene | PLCB4 | chr20:9424890 | chr13:114762215 | ENST00000378501 | + | 28 | 36 | 565_681 | 948 | 1195.0 | Domain | PI-PLC Y-box |
| Hgene | PLCB4 | chr20:9424890 | chr13:114762215 | ENST00000378501 | + | 28 | 36 | 684_809 | 948 | 1195.0 | Domain | C2 |
| Tgene | RASA3 | chr20:9424890 | chr13:114762215 | ENST00000334062 | 19 | 24 | 679_715 | 644 | 835.0 | Zinc finger | Btk-type |
| - In-frame and not-retained protein feature among the 13 regional features. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Protein feature | Protein feature note |
| Tgene | RASA3 | chr20:9424890 | chr13:114762215 | ENST00000334062 | 19 | 24 | 123_263 | 644 | 835.0 | Domain | C2 2 | |
| Tgene | RASA3 | chr20:9424890 | chr13:114762215 | ENST00000334062 | 19 | 24 | 1_112 | 644 | 835.0 | Domain | C2 1 | |
| Tgene | RASA3 | chr20:9424890 | chr13:114762215 | ENST00000334062 | 19 | 24 | 330_524 | 644 | 835.0 | Domain | Ras-GAP | |
| Tgene | RASA3 | chr20:9424890 | chr13:114762215 | ENST00000334062 | 19 | 24 | 576_677 | 644 | 835.0 | Domain | PH |
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Fusion Gene Sequence for PLCB4-RASA3 |
| For in-frame fusion transcripts, we provide the fusion transcript sequences and fusion amino acid sequences. To have fusion amino acid sequence, we ran ORFfinder and chose the longest ORF among the all predicted ones. |
| >66002_66002_1_PLCB4-RASA3_PLCB4_chr20_9424890_ENST00000278655_RASA3_chr13_114762215_ENST00000334062_length(transcript)=5059nt_BP=2922nt AGGACAGTGCTGCTGTGAGTTTGACGAAGTGGACATCACCTGCAGTCAGTCCAGAGCTGCCCAGTCTTGAATATAATCATGGCCAAACCT TATGAATTTAACTGGCAGAAGGAAGTTCCCTCCTTTTTGCAAGAAGGAGCAGTTTTTGACAGATACGAGGAGGAATCCTTTGTGTTTGAA CCCAACTGCCTCTTCAAAGTGGATGAGTTTGGCTTCTTTCTGACATGGAGAAGTGAAGGCAAGGAAGGACAGGTGCTAGAATGCTCCCTC ATCAACAGTATTCGGTCGGGAGCCATACCAAAGGATCCCAAAATCTTGGCTGCTCTTGAAGCTGTTGGAAAATCAGAAAATGATCTGGAA GGGCGGATAGTTTGTGTCTGCAGTGGCACAGATCTAGTGAACATTAGTTTTACCTACATGGTGGCTGAAAATCCAGAAGTAACTAAGCAA TGGGTAGAAGGCCTGAGATCAATCATACACAACTTCAGGGCCAACAACGTCAGTCCAATGACATGCCTCAAGAAACACTGGATGAAATTG GCATTTATGACCAACACAAATGGTAAAATTCCAGTTAGGAGTATTACTAGAACATTTGCATCGGGAAAAACAGAAAAGGTGATCTTTCAA GCACTCAAGGAGTTAGGTCTTCCCAGTGGAAAGAATGATGAAATTGAGCCCACAGCATTTTCTTATGAAAAGTTCTATGAACTGACACAA AAGATTTGTCCTCGGACAGATATAGAAGATCTTTTCAAAAAAATCAATGGAGACAAAACTGATTATTTAACGGTAGACCAATTAGTGAGC TTTCTAAATGAACATCAACGAGATCCTCGATTGAATGAAATTTTATTTCCATTTTATGATGCCAAAAGGGCAATGCAGATCATTGAGATG TATGAACCTGATGAAGATTTGAAGAAAAAAGGCCTTATATCAAGTGATGGGTTTTGCAGATATCTGATGTCAGATGAAAACGCCCCAGTC TTCCTAGATCGTTTAGAACTTTACCAAGAAATGGACCATCCTCTGGCTCACTACTTCATCAGTTCTTCCCATAACACTTATCTCACTGGC AGACAGTTCGGCGGGAAGTCTTCGGTAGAAATGTACAGACAGGTTCTCCTGGCTGGTTGCAGATGTGTTGAACTTGACTGCTGGGATGGA AAAGGTGAAGACCAAGAACCAATAATAACTCATGGAAAAGCAATGTGTACAGATATCCTTTTTAAGGATGTAATTCAAGCCATCAAGGAA ACTGCATTTGTCACATCAGAATATCCTGTAATTCTCTCCTTTGAAAATCACTGCAGCAAATATCAACAGTACAAGATGTCCAAATATTGC GAAGATCTATTTGGGGATCTCCTGTTGAAACAAGCACTTGAATCACATCCACTTGAACCAGGCAGGGCTTTGCCATCCCCCAATGACCTC AAAAGAAAAATACTCATAAAAAACAAGCGGCTGAAACCTGAAGTTGAAAAAAAACAGCTGGAAGCTTTGAGAAGCATGATGGAAGCTGGA GAATCTGCCTCCCCAGCAAACATCTTAGAGGACGATAATGAAGAGGAGATCGAAAGTGCTGACCAAGAGGAGGAAGCTCACCCCGAATTC AAATTTGGAAATGAACTTTCTGCTGATGACTTGGGTCACAAGGAAGCTGTTGCAAATAGCGTCAAGAAGGGCCTGGTCACTGTAGAAGAT GAGCAGGCGTGGATGGCATCTTATAAATATGTAGGTGCTACCACTAATATCCATCCATATTTGTCCACAATGATCAACTACGCCCAGCCT GTAAAGTTTCAAGGTTTCCATGTGGCAGAAGAACGCAATATTCATTATAACATGTCTTCTTTTAATGAATCAGTCGGTCTTGGCTACTTG AAGACACATGCAATTGAATTTGTCAATTATAACAAACGGCAAATGAGTCGCATTTACCCCAAGGGAGGCCGAGTCGATTCCAGTAATTAC ATGCCTCAGATTTTCTGGAACGCTGGCTGCCAGATGGTTTCACTGAACTATCAAACCCCAGATTTAGCGATGCAATTGAATCAGGGAAAA TTTGAGTATAATGGATCGTGCGGGTACCTTCTCAAACCAGATTTCATGAGGCGGCCTGATCGAACATTTGACCCCTTCTCTGAAACTCCT GTTGATGGTGTTATTGCAGCCACTTGCTCAGTGCAGGTTATATCAGGTCAATTCTTATCAGATAAGAAAATTGGCACCTACGTAGAGGTG GATATGTATGGGTTGCCCACTGACACCATACGTAAGGAATTCCGAACTCGCATGGTTATGAATAATGGACTCAATCCAGTTTACAATGAA GAGTCATTTGTATTTCGGAAGGTGATCCTGCCGGACCTGGCTGTCTTGAGAATAGCTGTGTATGATGATAACAACAAGCTGATTGGCCAG AGGATCCTCCCGCTTGATGGCCTCCAAGCCGGATATCGACACATTTCCCTTCGAAATGAGGGAAATAAACCATTATCACTACCAACAATT TTCTGCAATATTGTTCTTAAAACATATGTGCCTGATGGATTTGGAGATATCGTGGATGCTTTATCAGATCCAAAGAAATTTCTCTCAATT ACAGAAAAGAGAGCAGACCAAATGAGAGCTATGGGCATTGAAACTAGTGACATAGCCGACGTGCCCAGTGACACTTCCAAAAATGACAAG AAAGGAAAGGCCAACACCGCCAAAGCAAATGTGACCCCTCAGAGTAGCTCTGAGCTCAGACCAACCACCACGGCTGCCCTGGCCTCTGGT GTGGAAGCCAAGAAAGGTATTGAACTTATCCCTCAAGTAAGGATAGAAGACTTAAAGCAGATGAAGGCTTACTTGAAGCATTTAAAGAAA CAGCAGAAGGAGCTAAATTCTTTAAAGAAGAAACATGCAAAGATGTTCCAGGTCATCCAGCCAGAGCGTGCGCTGTACATCCAGGCCAAC AACTGCGTGGAGGCCAAGGACTGGATCGACATTCTCACCAAAGTGAGCCAGTGCAACCAGAAGCGCCTCACCGTCTACCACCCGTCCGCC TACCTGAGCGGCCACTGGCTGTGCTGTAGGGCGCCATCCGACTCGGCTCCGGGCTGCTCGCCCTGCACTGGCGGCCTCCCAGCCAACATC CAGCTGGACATTGATGGGGACCGTGAGACGGAGCGTATCTACTCCCTCTTCAACTTGTACATGAGCAAGCTGGAGAAGATGCAGGAGGCC TGTGGGAGCAAATCTGTGTATGACGGCCCGGAGCAGGAGGAGTATTCGACGTTCGTCATTGACGACCCCCAGGAGACCTACAAGACGCTA AAGCAAGTCATCGCTGGGGTTGGGGCTTTGGAGCAGGAGCACGCCCAGTATAAGAGGGACAAGTTCAAGAAGACGAAATATGGAAGCCAG GAGCACCCCATCGGAGACAAGAGCTTCCAGAACTACATCCGGCAGCAGTCCGAGACCTCCACTCATTCCATTTAAAGTCTGCGGGACGCG CCCAGTGGCGCCAGCAAGCTGCCCATGCAAAGCCGCAGCCTTTGGGAGGGAGAAGAGAAGGAAGAGCGCAGAGCCGGCAAAGTGAGATGC ACGCCGTCCCGGCCCATAGACAAGTGGCGCTGGGGTTTCCCTCTCCCAGAACCGCTGCCACCACCGCCACGCCCTCCGCAGAAAGCCCAC CTGGCCCTGTGGAACGTGTCGTCATTTGATTCTGTGCTTTTTGCTCCTTGTTTGTGGGGATCTGGGGATCAGCTGAAGGATCAGGAAGTG TGGGCTGTGCCCTAGCCACACCACAGCCAGCCTCAGGGAGCCACGGCCCGTCTAGTCGACTGTGACATGCACCTCCGGCCGTGTGTGCGT CAGTCTCGTGCACGTCTGTCTTGCGTGCACGGTGCGTGTGACGCTGGGCTCTGTGGCTCTGTGCCCGGGAGGCCTGCTGGCCCCGCCTCG GCTTTCGGCTTCATCACATTGGGAGGTTCAGAGCATTACTCTCCCACTGTGCCTGCCATCCAGGCAGCCATGGGAGGCGGCCTCCCTGTT CCACTTTCGAGGTTCGTTTGATTCCTGGCTGAGGGGTCAGTTTTATGGCTGGGAGGTGCAGAATTACACAGAAGTCCCAGTCTGAGGATG TCCTTGGTGCTTGGGGGATACGGGTTCTGTCCACAGAGTCCCTTGGAGGGAAAGGTGTGGGCTCCAGCTTCTCCAGGCGTCTGCGGAGCC CACAGTTGAAGCCCACATCGTTTTGCTGTTGAATGGGGTTTAAAATCAGAATTAACATTTGCCACCCCCCGTGGAAGTTTGAAGATTTTA AAAATAGAAATGTACATTTTTCAAGCTGTTTTTCTTTATGTTTTTGAAGGACCATTTTTAATTAGCTCTTTGATACAAAGTAACTCAGAA CGTCAAAACCTATACCCACTAAAGGGAAGGCTGCCGGGAAGGCAAATGGAACAGGAATGGAGCCTGTCTCAGGAAGGCCAGCTGCAGGTC CTCCAGAAAATCAAAGAAGGGAAGAAACTCTGAGTTTGAGGTACAGGGGCTTCGGGGTGCAGACGTCCCTCCAGGGCCCATGGTCAGTAT TGCACCTGTGTTATGAACCCCCAGATGCTGTGCAGGGCAGGGGCGGGGGCTGCTGTTTTATTGGGGAGGGGAGCATCCTAAAAATGGGGT CCAGGCAGACCCCTCCAGACCTCACACTGCCGAGGAGGCCTTTCCCAAAGGGCGTCCTCCCGGGATGCAGACGGCAGGTGTGTGGGAAGC GCCGTTTAAATACACAGCACGACGTATCCTTGTACCGACTTCTCCCGGTTCTTGTTTGAAAATACTGTAGTTCAGGCTCTTGATCTAGAT GGCAGATAGGAACTTTCTTGTCACAAAAATACTGGAGGAAAATGTTGTAAAAATAGACTTTTGGACACACAGCTGTTGGGGCTGCACTGA GCTGCAATTTTTAACATGGATTTATAACTTAATGTTTCTGTTTATAAAATACTAATGATTTGCAATGTATTTTACTGGCCAATTAAAACA >66002_66002_1_PLCB4-RASA3_PLCB4_chr20_9424890_ENST00000278655_RASA3_chr13_114762215_ENST00000334062_length(amino acids)=1151AA_BP=961 MQSVQSCPVLNIIMAKPYEFNWQKEVPSFLQEGAVFDRYEEESFVFEPNCLFKVDEFGFFLTWRSEGKEGQVLECSLINSIRSGAIPKDP KILAALEAVGKSENDLEGRIVCVCSGTDLVNISFTYMVAENPEVTKQWVEGLRSIIHNFRANNVSPMTCLKKHWMKLAFMTNTNGKIPVR SITRTFASGKTEKVIFQALKELGLPSGKNDEIEPTAFSYEKFYELTQKICPRTDIEDLFKKINGDKTDYLTVDQLVSFLNEHQRDPRLNE ILFPFYDAKRAMQIIEMYEPDEDLKKKGLISSDGFCRYLMSDENAPVFLDRLELYQEMDHPLAHYFISSSHNTYLTGRQFGGKSSVEMYR QVLLAGCRCVELDCWDGKGEDQEPIITHGKAMCTDILFKDVIQAIKETAFVTSEYPVILSFENHCSKYQQYKMSKYCEDLFGDLLLKQAL ESHPLEPGRALPSPNDLKRKILIKNKRLKPEVEKKQLEALRSMMEAGESASPANILEDDNEEEIESADQEEEAHPEFKFGNELSADDLGH KEAVANSVKKGLVTVEDEQAWMASYKYVGATTNIHPYLSTMINYAQPVKFQGFHVAEERNIHYNMSSFNESVGLGYLKTHAIEFVNYNKR QMSRIYPKGGRVDSSNYMPQIFWNAGCQMVSLNYQTPDLAMQLNQGKFEYNGSCGYLLKPDFMRRPDRTFDPFSETPVDGVIAATCSVQV ISGQFLSDKKIGTYVEVDMYGLPTDTIRKEFRTRMVMNNGLNPVYNEESFVFRKVILPDLAVLRIAVYDDNNKLIGQRILPLDGLQAGYR HISLRNEGNKPLSLPTIFCNIVLKTYVPDGFGDIVDALSDPKKFLSITEKRADQMRAMGIETSDIADVPSDTSKNDKKGKANTAKANVTP QSSSELRPTTTAALASGVEAKKGIELIPQVRIEDLKQMKAYLKHLKKQQKELNSLKKKHAKMFQVIQPERALYIQANNCVEAKDWIDILT KVSQCNQKRLTVYHPSAYLSGHWLCCRAPSDSAPGCSPCTGGLPANIQLDIDGDRETERIYSLFNLYMSKLEKMQEACGSKSVYDGPEQE -------------------------------------------------------------- >66002_66002_2_PLCB4-RASA3_PLCB4_chr20_9424890_ENST00000278655_RASA3_chr13_114762215_ENST00000389544_length(transcript)=3815nt_BP=2922nt AGGACAGTGCTGCTGTGAGTTTGACGAAGTGGACATCACCTGCAGTCAGTCCAGAGCTGCCCAGTCTTGAATATAATCATGGCCAAACCT TATGAATTTAACTGGCAGAAGGAAGTTCCCTCCTTTTTGCAAGAAGGAGCAGTTTTTGACAGATACGAGGAGGAATCCTTTGTGTTTGAA CCCAACTGCCTCTTCAAAGTGGATGAGTTTGGCTTCTTTCTGACATGGAGAAGTGAAGGCAAGGAAGGACAGGTGCTAGAATGCTCCCTC ATCAACAGTATTCGGTCGGGAGCCATACCAAAGGATCCCAAAATCTTGGCTGCTCTTGAAGCTGTTGGAAAATCAGAAAATGATCTGGAA GGGCGGATAGTTTGTGTCTGCAGTGGCACAGATCTAGTGAACATTAGTTTTACCTACATGGTGGCTGAAAATCCAGAAGTAACTAAGCAA TGGGTAGAAGGCCTGAGATCAATCATACACAACTTCAGGGCCAACAACGTCAGTCCAATGACATGCCTCAAGAAACACTGGATGAAATTG GCATTTATGACCAACACAAATGGTAAAATTCCAGTTAGGAGTATTACTAGAACATTTGCATCGGGAAAAACAGAAAAGGTGATCTTTCAA GCACTCAAGGAGTTAGGTCTTCCCAGTGGAAAGAATGATGAAATTGAGCCCACAGCATTTTCTTATGAAAAGTTCTATGAACTGACACAA AAGATTTGTCCTCGGACAGATATAGAAGATCTTTTCAAAAAAATCAATGGAGACAAAACTGATTATTTAACGGTAGACCAATTAGTGAGC TTTCTAAATGAACATCAACGAGATCCTCGATTGAATGAAATTTTATTTCCATTTTATGATGCCAAAAGGGCAATGCAGATCATTGAGATG TATGAACCTGATGAAGATTTGAAGAAAAAAGGCCTTATATCAAGTGATGGGTTTTGCAGATATCTGATGTCAGATGAAAACGCCCCAGTC TTCCTAGATCGTTTAGAACTTTACCAAGAAATGGACCATCCTCTGGCTCACTACTTCATCAGTTCTTCCCATAACACTTATCTCACTGGC AGACAGTTCGGCGGGAAGTCTTCGGTAGAAATGTACAGACAGGTTCTCCTGGCTGGTTGCAGATGTGTTGAACTTGACTGCTGGGATGGA AAAGGTGAAGACCAAGAACCAATAATAACTCATGGAAAAGCAATGTGTACAGATATCCTTTTTAAGGATGTAATTCAAGCCATCAAGGAA ACTGCATTTGTCACATCAGAATATCCTGTAATTCTCTCCTTTGAAAATCACTGCAGCAAATATCAACAGTACAAGATGTCCAAATATTGC GAAGATCTATTTGGGGATCTCCTGTTGAAACAAGCACTTGAATCACATCCACTTGAACCAGGCAGGGCTTTGCCATCCCCCAATGACCTC AAAAGAAAAATACTCATAAAAAACAAGCGGCTGAAACCTGAAGTTGAAAAAAAACAGCTGGAAGCTTTGAGAAGCATGATGGAAGCTGGA GAATCTGCCTCCCCAGCAAACATCTTAGAGGACGATAATGAAGAGGAGATCGAAAGTGCTGACCAAGAGGAGGAAGCTCACCCCGAATTC AAATTTGGAAATGAACTTTCTGCTGATGACTTGGGTCACAAGGAAGCTGTTGCAAATAGCGTCAAGAAGGGCCTGGTCACTGTAGAAGAT GAGCAGGCGTGGATGGCATCTTATAAATATGTAGGTGCTACCACTAATATCCATCCATATTTGTCCACAATGATCAACTACGCCCAGCCT GTAAAGTTTCAAGGTTTCCATGTGGCAGAAGAACGCAATATTCATTATAACATGTCTTCTTTTAATGAATCAGTCGGTCTTGGCTACTTG AAGACACATGCAATTGAATTTGTCAATTATAACAAACGGCAAATGAGTCGCATTTACCCCAAGGGAGGCCGAGTCGATTCCAGTAATTAC ATGCCTCAGATTTTCTGGAACGCTGGCTGCCAGATGGTTTCACTGAACTATCAAACCCCAGATTTAGCGATGCAATTGAATCAGGGAAAA TTTGAGTATAATGGATCGTGCGGGTACCTTCTCAAACCAGATTTCATGAGGCGGCCTGATCGAACATTTGACCCCTTCTCTGAAACTCCT GTTGATGGTGTTATTGCAGCCACTTGCTCAGTGCAGGTTATATCAGGTCAATTCTTATCAGATAAGAAAATTGGCACCTACGTAGAGGTG GATATGTATGGGTTGCCCACTGACACCATACGTAAGGAATTCCGAACTCGCATGGTTATGAATAATGGACTCAATCCAGTTTACAATGAA GAGTCATTTGTATTTCGGAAGGTGATCCTGCCGGACCTGGCTGTCTTGAGAATAGCTGTGTATGATGATAACAACAAGCTGATTGGCCAG AGGATCCTCCCGCTTGATGGCCTCCAAGCCGGATATCGACACATTTCCCTTCGAAATGAGGGAAATAAACCATTATCACTACCAACAATT TTCTGCAATATTGTTCTTAAAACATATGTGCCTGATGGATTTGGAGATATCGTGGATGCTTTATCAGATCCAAAGAAATTTCTCTCAATT ACAGAAAAGAGAGCAGACCAAATGAGAGCTATGGGCATTGAAACTAGTGACATAGCCGACGTGCCCAGTGACACTTCCAAAAATGACAAG AAAGGAAAGGCCAACACCGCCAAAGCAAATGTGACCCCTCAGAGTAGCTCTGAGCTCAGACCAACCACCACGGCTGCCCTGGCCTCTGGT GTGGAAGCCAAGAAAGGTATTGAACTTATCCCTCAAGTAAGGATAGAAGACTTAAAGCAGATGAAGGCTTACTTGAAGCATTTAAAGAAA CAGCAGAAGGAGCTAAATTCTTTAAAGAAGAAACATGCAAAGATGTTCCAGGTCATCCAGCCAGAGCGTGCGCTGTACATCCAGGCCAAC AACTGCGTGGAGGCCAAGGACTGGATCGACATTCTCACCAAAGTGAGCCAGTGCAACCAGAAGCGCCTCACCGTCTACCACCCGTCCGCC TACCTGAGCGGCCACTGGCTGTGCTGTAGGGCGCCATCCGACTCGGCTCCGGGCTGCTCGCCCTGCACTGGCGGCCTCCCAGCCAACATC CAGCTGGACATTGATGGGGACCGTGAGACGGAGCGTATCTACTCCCTCTTCAACTTGTACATGAGCAAGCTGGAGAAGATGCAGGAGGCC TGTGGGAGCAAATCTGTGTATGACGGCCCGGAGCAGGAGGAGTATTCGACGTTCGTCATTGACGACCCCCAGGAGACCTACAAGACGCTA AAGCAAGTCATCGCTGGGGTTGGGGCTTTGGAGCAGGAGCACGCCCAGTATAAGAGGGACAAGTTCAAGAAGACGAAATATGGAAGCCAG GAGCACCCCATCGGAGACAAGAGCTTCCAGAACTACATCCGGCAGCAGTCCGAGACCTCCACTCATTCCATTTAAAGTCTGCGGGACGCG CCCAGTGGCGCCAGCAAGCTGCCCATGCAAAGCCGCAGCCTTTGGGAGGGAGAAGAGAAGGAAGAGCGCAGAGCCGGCAAAGTGAGATGC ACGCCGTCCCGGCCCATAGACAAGTGGCGCTGGGGTTTCCCTCTCCCAGAACCGCTGCCACCACCGCCACGCCCTCCGCAGAAAGCCCAC CTGGCCCTGTGGAACGTGTCGTCATTTGATTCTGTGCTTTTTGCTCCTTGTTTGTGGGGATCTGGGGATCAGCTGAAGGATCAGGAAGTG >66002_66002_2_PLCB4-RASA3_PLCB4_chr20_9424890_ENST00000278655_RASA3_chr13_114762215_ENST00000389544_length(amino acids)=1151AA_BP=961 MQSVQSCPVLNIIMAKPYEFNWQKEVPSFLQEGAVFDRYEEESFVFEPNCLFKVDEFGFFLTWRSEGKEGQVLECSLINSIRSGAIPKDP KILAALEAVGKSENDLEGRIVCVCSGTDLVNISFTYMVAENPEVTKQWVEGLRSIIHNFRANNVSPMTCLKKHWMKLAFMTNTNGKIPVR SITRTFASGKTEKVIFQALKELGLPSGKNDEIEPTAFSYEKFYELTQKICPRTDIEDLFKKINGDKTDYLTVDQLVSFLNEHQRDPRLNE ILFPFYDAKRAMQIIEMYEPDEDLKKKGLISSDGFCRYLMSDENAPVFLDRLELYQEMDHPLAHYFISSSHNTYLTGRQFGGKSSVEMYR QVLLAGCRCVELDCWDGKGEDQEPIITHGKAMCTDILFKDVIQAIKETAFVTSEYPVILSFENHCSKYQQYKMSKYCEDLFGDLLLKQAL ESHPLEPGRALPSPNDLKRKILIKNKRLKPEVEKKQLEALRSMMEAGESASPANILEDDNEEEIESADQEEEAHPEFKFGNELSADDLGH KEAVANSVKKGLVTVEDEQAWMASYKYVGATTNIHPYLSTMINYAQPVKFQGFHVAEERNIHYNMSSFNESVGLGYLKTHAIEFVNYNKR QMSRIYPKGGRVDSSNYMPQIFWNAGCQMVSLNYQTPDLAMQLNQGKFEYNGSCGYLLKPDFMRRPDRTFDPFSETPVDGVIAATCSVQV ISGQFLSDKKIGTYVEVDMYGLPTDTIRKEFRTRMVMNNGLNPVYNEESFVFRKVILPDLAVLRIAVYDDNNKLIGQRILPLDGLQAGYR HISLRNEGNKPLSLPTIFCNIVLKTYVPDGFGDIVDALSDPKKFLSITEKRADQMRAMGIETSDIADVPSDTSKNDKKGKANTAKANVTP QSSSELRPTTTAALASGVEAKKGIELIPQVRIEDLKQMKAYLKHLKKQQKELNSLKKKHAKMFQVIQPERALYIQANNCVEAKDWIDILT KVSQCNQKRLTVYHPSAYLSGHWLCCRAPSDSAPGCSPCTGGLPANIQLDIDGDRETERIYSLFNLYMSKLEKMQEACGSKSVYDGPEQE -------------------------------------------------------------- >66002_66002_3_PLCB4-RASA3_PLCB4_chr20_9424890_ENST00000334005_RASA3_chr13_114762215_ENST00000334062_length(transcript)=5212nt_BP=3075nt AGTAAGTGAGCTGCACCGCCAACAAGATCTCTCACACACAGACACACACACGCACACGCACACACGGGCGCGCACACACACGCGCGTACA CACTGGGTCTCCAGGCAGCGGCCGTCGCCGCATCCCCGGCAGCAGCTCCAGGCAAAGTGACAGAGGACAGTGCTGCTGTGAGTTTGACGA AGTGGACATCACCTGCAGTCAGTCCAGAGCTGCCCAGTCTTGAATATAATCATGGCCAAACCTTATGAATTTAACTGGCAGAAGGAAGTT CCCTCCTTTTTGCAAGAAGGAGCAGTTTTTGACAGATACGAGGAGGAATCCTTTGTGTTTGAACCCAACTGCCTCTTCAAAGTGGATGAG TTTGGCTTCTTTCTGACATGGAGAAGTGAAGGCAAGGAAGGACAGGTGCTAGAATGCTCCCTCATCAACAGTATTCGGTCGGGAGCCATA CCAAAGGATCCCAAAATCTTGGCTGCTCTTGAAGCTGTTGGAAAATCAGAAAATGATCTGGAAGGGCGGATAGTTTGTGTCTGCAGTGGC ACAGATCTAGTGAACATTAGTTTTACCTACATGGTGGCTGAAAATCCAGAAGTAACTAAGCAATGGGTAGAAGGCCTGAGATCAATCATA CACAACTTCAGGGCCAACAACGTCAGTCCAATGACATGCCTCAAGAAACACTGGATGAAATTGGCATTTATGACCAACACAAATGGTAAA ATTCCAGTTAGGAGTATTACTAGAACATTTGCATCGGGAAAAACAGAAAAGGTGATCTTTCAAGCACTCAAGGAGTTAGGTCTTCCCAGT GGAAAGAATGATGAAATTGAGCCCACAGCATTTTCTTATGAAAAGTTCTATGAACTGACACAAAAGATTTGTCCTCGGACAGATATAGAA GATCTTTTCAAAAAAATCAATGGAGACAAAACTGATTATTTAACGGTAGACCAATTAGTGAGCTTTCTAAATGAACATCAACGAGATCCT CGATTGAATGAAATTTTATTTCCATTTTATGATGCCAAAAGGGCAATGCAGATCATTGAGATGTATGAACCTGATGAAGATTTGAAGAAA AAAGGCCTTATATCAAGTGATGGGTTTTGCAGATATCTGATGTCAGATGAAAACGCCCCAGTCTTCCTAGATCGTTTAGAACTTTACCAA GAAATGGACCATCCTCTGGCTCACTACTTCATCAGTTCTTCCCATAACACTTATCTCACTGGCAGACAGTTCGGCGGGAAGTCTTCGGTA GAAATGTACAGACAGGTTCTCCTGGCTGGTTGCAGATGTGTTGAACTTGACTGCTGGGATGGAAAAGGTGAAGACCAAGAACCAATAATA ACTCATGGAAAAGCAATGTGTACAGATATCCTTTTTAAGGATGTAATTCAAGCCATCAAGGAAACTGCATTTGTCACATCAGAATATCCT GTAATTCTCTCCTTTGAAAATCACTGCAGCAAATATCAACAGTACAAGATGTCCAAATATTGCGAAGATCTATTTGGGGATCTCCTGTTG AAACAAGCACTTGAATCACATCCACTTGAACCAGGCAGGGCTTTGCCATCCCCCAATGACCTCAAAAGAAAAATACTCATAAAAAACAAG CGGCTGAAACCTGAAGTTGAAAAAAAACAGCTGGAAGCTTTGAGAAGCATGATGGAAGCTGGAGAATCTGCCTCCCCAGCAAACATCTTA GAGGACGATAATGAAGAGGAGATCGAAAGTGCTGACCAAGAGGAGGAAGCTCACCCCGAATTCAAATTTGGAAATGAACTTTCTGCTGAT GACTTGGGTCACAAGGAAGCTGTTGCAAATAGCGTCAAGAAGGGCCTGGTCACTGTAGAAGATGAGCAGGCGTGGATGGCATCTTATAAA TATGTAGGTGCTACCACTAATATCCATCCATATTTGTCCACAATGATCAACTACGCCCAGCCTGTAAAGTTTCAAGGTTTCCATGTGGCA GAAGAACGCAATATTCATTATAACATGTCTTCTTTTAATGAATCAGTCGGTCTTGGCTACTTGAAGACACATGCAATTGAATTTGTCAAT TATAACAAACGGCAAATGAGTCGCATTTACCCCAAGGGAGGCCGAGTCGATTCCAGTAATTACATGCCTCAGATTTTCTGGAACGCTGGC TGCCAGATGGTTTCACTGAACTATCAAACCCCAGATTTAGCGATGCAATTGAATCAGGGAAAATTTGAGTATAATGGATCGTGCGGGTAC CTTCTCAAACCAGATTTCATGAGGCGGCCTGATCGAACATTTGACCCCTTCTCTGAAACTCCTGTTGATGGTGTTATTGCAGCCACTTGC TCAGTGCAGGTTATATCAGGTCAATTCTTATCAGATAAGAAAATTGGCACCTACGTAGAGGTGGATATGTATGGGTTGCCCACTGACACC ATACGTAAGGAATTCCGAACTCGCATGGTTATGAATAATGGACTCAATCCAGTTTACAATGAAGAGTCATTTGTATTTCGGAAGGTGATC CTGCCGGACCTGGCTGTCTTGAGAATAGCTGTGTATGATGATAACAACAAGCTGATTGGCCAGAGGATCCTCCCGCTTGATGGCCTCCAA GCCGGATATCGACACATTTCCCTTCGAAATGAGGGAAATAAACCATTATCACTACCAACAATTTTCTGCAATATTGTTCTTAAAACATAT GTGCCTGATGGATTTGGAGATATCGTGGATGCTTTATCAGATCCAAAGAAATTTCTCTCAATTACAGAAAAGAGAGCAGACCAAATGAGA GCTATGGGCATTGAAACTAGTGACATAGCCGACGTGCCCAGTGACACTTCCAAAAATGACAAGAAAGGAAAGGCCAACACCGCCAAAGCA AATGTGACCCCTCAGAGTAGCTCTGAGCTCAGACCAACCACCACGGCTGCCCTGGCCTCTGGTGTGGAAGCCAAGAAAGGTATTGAACTT ATCCCTCAAGTAAGGATAGAAGACTTAAAGCAGATGAAGGCTTACTTGAAGCATTTAAAGAAACAGCAGAAGGAGCTAAATTCTTTAAAG AAGAAACATGCAAAGATGTTCCAGGTCATCCAGCCAGAGCGTGCGCTGTACATCCAGGCCAACAACTGCGTGGAGGCCAAGGACTGGATC GACATTCTCACCAAAGTGAGCCAGTGCAACCAGAAGCGCCTCACCGTCTACCACCCGTCCGCCTACCTGAGCGGCCACTGGCTGTGCTGT AGGGCGCCATCCGACTCGGCTCCGGGCTGCTCGCCCTGCACTGGCGGCCTCCCAGCCAACATCCAGCTGGACATTGATGGGGACCGTGAG ACGGAGCGTATCTACTCCCTCTTCAACTTGTACATGAGCAAGCTGGAGAAGATGCAGGAGGCCTGTGGGAGCAAATCTGTGTATGACGGC CCGGAGCAGGAGGAGTATTCGACGTTCGTCATTGACGACCCCCAGGAGACCTACAAGACGCTAAAGCAAGTCATCGCTGGGGTTGGGGCT TTGGAGCAGGAGCACGCCCAGTATAAGAGGGACAAGTTCAAGAAGACGAAATATGGAAGCCAGGAGCACCCCATCGGAGACAAGAGCTTC CAGAACTACATCCGGCAGCAGTCCGAGACCTCCACTCATTCCATTTAAAGTCTGCGGGACGCGCCCAGTGGCGCCAGCAAGCTGCCCATG CAAAGCCGCAGCCTTTGGGAGGGAGAAGAGAAGGAAGAGCGCAGAGCCGGCAAAGTGAGATGCACGCCGTCCCGGCCCATAGACAAGTGG CGCTGGGGTTTCCCTCTCCCAGAACCGCTGCCACCACCGCCACGCCCTCCGCAGAAAGCCCACCTGGCCCTGTGGAACGTGTCGTCATTT GATTCTGTGCTTTTTGCTCCTTGTTTGTGGGGATCTGGGGATCAGCTGAAGGATCAGGAAGTGTGGGCTGTGCCCTAGCCACACCACAGC CAGCCTCAGGGAGCCACGGCCCGTCTAGTCGACTGTGACATGCACCTCCGGCCGTGTGTGCGTCAGTCTCGTGCACGTCTGTCTTGCGTG CACGGTGCGTGTGACGCTGGGCTCTGTGGCTCTGTGCCCGGGAGGCCTGCTGGCCCCGCCTCGGCTTTCGGCTTCATCACATTGGGAGGT TCAGAGCATTACTCTCCCACTGTGCCTGCCATCCAGGCAGCCATGGGAGGCGGCCTCCCTGTTCCACTTTCGAGGTTCGTTTGATTCCTG GCTGAGGGGTCAGTTTTATGGCTGGGAGGTGCAGAATTACACAGAAGTCCCAGTCTGAGGATGTCCTTGGTGCTTGGGGGATACGGGTTC TGTCCACAGAGTCCCTTGGAGGGAAAGGTGTGGGCTCCAGCTTCTCCAGGCGTCTGCGGAGCCCACAGTTGAAGCCCACATCGTTTTGCT GTTGAATGGGGTTTAAAATCAGAATTAACATTTGCCACCCCCCGTGGAAGTTTGAAGATTTTAAAAATAGAAATGTACATTTTTCAAGCT GTTTTTCTTTATGTTTTTGAAGGACCATTTTTAATTAGCTCTTTGATACAAAGTAACTCAGAACGTCAAAACCTATACCCACTAAAGGGA AGGCTGCCGGGAAGGCAAATGGAACAGGAATGGAGCCTGTCTCAGGAAGGCCAGCTGCAGGTCCTCCAGAAAATCAAAGAAGGGAAGAAA CTCTGAGTTTGAGGTACAGGGGCTTCGGGGTGCAGACGTCCCTCCAGGGCCCATGGTCAGTATTGCACCTGTGTTATGAACCCCCAGATG CTGTGCAGGGCAGGGGCGGGGGCTGCTGTTTTATTGGGGAGGGGAGCATCCTAAAAATGGGGTCCAGGCAGACCCCTCCAGACCTCACAC TGCCGAGGAGGCCTTTCCCAAAGGGCGTCCTCCCGGGATGCAGACGGCAGGTGTGTGGGAAGCGCCGTTTAAATACACAGCACGACGTAT CCTTGTACCGACTTCTCCCGGTTCTTGTTTGAAAATACTGTAGTTCAGGCTCTTGATCTAGATGGCAGATAGGAACTTTCTTGTCACAAA AATACTGGAGGAAAATGTTGTAAAAATAGACTTTTGGACACACAGCTGTTGGGGCTGCACTGAGCTGCAATTTTTAACATGGATTTATAA >66002_66002_3_PLCB4-RASA3_PLCB4_chr20_9424890_ENST00000334005_RASA3_chr13_114762215_ENST00000334062_length(amino acids)=1151AA_BP=961 MQSVQSCPVLNIIMAKPYEFNWQKEVPSFLQEGAVFDRYEEESFVFEPNCLFKVDEFGFFLTWRSEGKEGQVLECSLINSIRSGAIPKDP KILAALEAVGKSENDLEGRIVCVCSGTDLVNISFTYMVAENPEVTKQWVEGLRSIIHNFRANNVSPMTCLKKHWMKLAFMTNTNGKIPVR SITRTFASGKTEKVIFQALKELGLPSGKNDEIEPTAFSYEKFYELTQKICPRTDIEDLFKKINGDKTDYLTVDQLVSFLNEHQRDPRLNE ILFPFYDAKRAMQIIEMYEPDEDLKKKGLISSDGFCRYLMSDENAPVFLDRLELYQEMDHPLAHYFISSSHNTYLTGRQFGGKSSVEMYR QVLLAGCRCVELDCWDGKGEDQEPIITHGKAMCTDILFKDVIQAIKETAFVTSEYPVILSFENHCSKYQQYKMSKYCEDLFGDLLLKQAL ESHPLEPGRALPSPNDLKRKILIKNKRLKPEVEKKQLEALRSMMEAGESASPANILEDDNEEEIESADQEEEAHPEFKFGNELSADDLGH KEAVANSVKKGLVTVEDEQAWMASYKYVGATTNIHPYLSTMINYAQPVKFQGFHVAEERNIHYNMSSFNESVGLGYLKTHAIEFVNYNKR QMSRIYPKGGRVDSSNYMPQIFWNAGCQMVSLNYQTPDLAMQLNQGKFEYNGSCGYLLKPDFMRRPDRTFDPFSETPVDGVIAATCSVQV ISGQFLSDKKIGTYVEVDMYGLPTDTIRKEFRTRMVMNNGLNPVYNEESFVFRKVILPDLAVLRIAVYDDNNKLIGQRILPLDGLQAGYR HISLRNEGNKPLSLPTIFCNIVLKTYVPDGFGDIVDALSDPKKFLSITEKRADQMRAMGIETSDIADVPSDTSKNDKKGKANTAKANVTP QSSSELRPTTTAALASGVEAKKGIELIPQVRIEDLKQMKAYLKHLKKQQKELNSLKKKHAKMFQVIQPERALYIQANNCVEAKDWIDILT KVSQCNQKRLTVYHPSAYLSGHWLCCRAPSDSAPGCSPCTGGLPANIQLDIDGDRETERIYSLFNLYMSKLEKMQEACGSKSVYDGPEQE -------------------------------------------------------------- >66002_66002_4_PLCB4-RASA3_PLCB4_chr20_9424890_ENST00000334005_RASA3_chr13_114762215_ENST00000389544_length(transcript)=3968nt_BP=3075nt AGTAAGTGAGCTGCACCGCCAACAAGATCTCTCACACACAGACACACACACGCACACGCACACACGGGCGCGCACACACACGCGCGTACA CACTGGGTCTCCAGGCAGCGGCCGTCGCCGCATCCCCGGCAGCAGCTCCAGGCAAAGTGACAGAGGACAGTGCTGCTGTGAGTTTGACGA AGTGGACATCACCTGCAGTCAGTCCAGAGCTGCCCAGTCTTGAATATAATCATGGCCAAACCTTATGAATTTAACTGGCAGAAGGAAGTT CCCTCCTTTTTGCAAGAAGGAGCAGTTTTTGACAGATACGAGGAGGAATCCTTTGTGTTTGAACCCAACTGCCTCTTCAAAGTGGATGAG TTTGGCTTCTTTCTGACATGGAGAAGTGAAGGCAAGGAAGGACAGGTGCTAGAATGCTCCCTCATCAACAGTATTCGGTCGGGAGCCATA CCAAAGGATCCCAAAATCTTGGCTGCTCTTGAAGCTGTTGGAAAATCAGAAAATGATCTGGAAGGGCGGATAGTTTGTGTCTGCAGTGGC ACAGATCTAGTGAACATTAGTTTTACCTACATGGTGGCTGAAAATCCAGAAGTAACTAAGCAATGGGTAGAAGGCCTGAGATCAATCATA CACAACTTCAGGGCCAACAACGTCAGTCCAATGACATGCCTCAAGAAACACTGGATGAAATTGGCATTTATGACCAACACAAATGGTAAA ATTCCAGTTAGGAGTATTACTAGAACATTTGCATCGGGAAAAACAGAAAAGGTGATCTTTCAAGCACTCAAGGAGTTAGGTCTTCCCAGT GGAAAGAATGATGAAATTGAGCCCACAGCATTTTCTTATGAAAAGTTCTATGAACTGACACAAAAGATTTGTCCTCGGACAGATATAGAA GATCTTTTCAAAAAAATCAATGGAGACAAAACTGATTATTTAACGGTAGACCAATTAGTGAGCTTTCTAAATGAACATCAACGAGATCCT CGATTGAATGAAATTTTATTTCCATTTTATGATGCCAAAAGGGCAATGCAGATCATTGAGATGTATGAACCTGATGAAGATTTGAAGAAA AAAGGCCTTATATCAAGTGATGGGTTTTGCAGATATCTGATGTCAGATGAAAACGCCCCAGTCTTCCTAGATCGTTTAGAACTTTACCAA GAAATGGACCATCCTCTGGCTCACTACTTCATCAGTTCTTCCCATAACACTTATCTCACTGGCAGACAGTTCGGCGGGAAGTCTTCGGTA GAAATGTACAGACAGGTTCTCCTGGCTGGTTGCAGATGTGTTGAACTTGACTGCTGGGATGGAAAAGGTGAAGACCAAGAACCAATAATA ACTCATGGAAAAGCAATGTGTACAGATATCCTTTTTAAGGATGTAATTCAAGCCATCAAGGAAACTGCATTTGTCACATCAGAATATCCT GTAATTCTCTCCTTTGAAAATCACTGCAGCAAATATCAACAGTACAAGATGTCCAAATATTGCGAAGATCTATTTGGGGATCTCCTGTTG AAACAAGCACTTGAATCACATCCACTTGAACCAGGCAGGGCTTTGCCATCCCCCAATGACCTCAAAAGAAAAATACTCATAAAAAACAAG CGGCTGAAACCTGAAGTTGAAAAAAAACAGCTGGAAGCTTTGAGAAGCATGATGGAAGCTGGAGAATCTGCCTCCCCAGCAAACATCTTA GAGGACGATAATGAAGAGGAGATCGAAAGTGCTGACCAAGAGGAGGAAGCTCACCCCGAATTCAAATTTGGAAATGAACTTTCTGCTGAT GACTTGGGTCACAAGGAAGCTGTTGCAAATAGCGTCAAGAAGGGCCTGGTCACTGTAGAAGATGAGCAGGCGTGGATGGCATCTTATAAA TATGTAGGTGCTACCACTAATATCCATCCATATTTGTCCACAATGATCAACTACGCCCAGCCTGTAAAGTTTCAAGGTTTCCATGTGGCA GAAGAACGCAATATTCATTATAACATGTCTTCTTTTAATGAATCAGTCGGTCTTGGCTACTTGAAGACACATGCAATTGAATTTGTCAAT TATAACAAACGGCAAATGAGTCGCATTTACCCCAAGGGAGGCCGAGTCGATTCCAGTAATTACATGCCTCAGATTTTCTGGAACGCTGGC TGCCAGATGGTTTCACTGAACTATCAAACCCCAGATTTAGCGATGCAATTGAATCAGGGAAAATTTGAGTATAATGGATCGTGCGGGTAC CTTCTCAAACCAGATTTCATGAGGCGGCCTGATCGAACATTTGACCCCTTCTCTGAAACTCCTGTTGATGGTGTTATTGCAGCCACTTGC TCAGTGCAGGTTATATCAGGTCAATTCTTATCAGATAAGAAAATTGGCACCTACGTAGAGGTGGATATGTATGGGTTGCCCACTGACACC ATACGTAAGGAATTCCGAACTCGCATGGTTATGAATAATGGACTCAATCCAGTTTACAATGAAGAGTCATTTGTATTTCGGAAGGTGATC CTGCCGGACCTGGCTGTCTTGAGAATAGCTGTGTATGATGATAACAACAAGCTGATTGGCCAGAGGATCCTCCCGCTTGATGGCCTCCAA GCCGGATATCGACACATTTCCCTTCGAAATGAGGGAAATAAACCATTATCACTACCAACAATTTTCTGCAATATTGTTCTTAAAACATAT GTGCCTGATGGATTTGGAGATATCGTGGATGCTTTATCAGATCCAAAGAAATTTCTCTCAATTACAGAAAAGAGAGCAGACCAAATGAGA GCTATGGGCATTGAAACTAGTGACATAGCCGACGTGCCCAGTGACACTTCCAAAAATGACAAGAAAGGAAAGGCCAACACCGCCAAAGCA AATGTGACCCCTCAGAGTAGCTCTGAGCTCAGACCAACCACCACGGCTGCCCTGGCCTCTGGTGTGGAAGCCAAGAAAGGTATTGAACTT ATCCCTCAAGTAAGGATAGAAGACTTAAAGCAGATGAAGGCTTACTTGAAGCATTTAAAGAAACAGCAGAAGGAGCTAAATTCTTTAAAG AAGAAACATGCAAAGATGTTCCAGGTCATCCAGCCAGAGCGTGCGCTGTACATCCAGGCCAACAACTGCGTGGAGGCCAAGGACTGGATC GACATTCTCACCAAAGTGAGCCAGTGCAACCAGAAGCGCCTCACCGTCTACCACCCGTCCGCCTACCTGAGCGGCCACTGGCTGTGCTGT AGGGCGCCATCCGACTCGGCTCCGGGCTGCTCGCCCTGCACTGGCGGCCTCCCAGCCAACATCCAGCTGGACATTGATGGGGACCGTGAG ACGGAGCGTATCTACTCCCTCTTCAACTTGTACATGAGCAAGCTGGAGAAGATGCAGGAGGCCTGTGGGAGCAAATCTGTGTATGACGGC CCGGAGCAGGAGGAGTATTCGACGTTCGTCATTGACGACCCCCAGGAGACCTACAAGACGCTAAAGCAAGTCATCGCTGGGGTTGGGGCT TTGGAGCAGGAGCACGCCCAGTATAAGAGGGACAAGTTCAAGAAGACGAAATATGGAAGCCAGGAGCACCCCATCGGAGACAAGAGCTTC CAGAACTACATCCGGCAGCAGTCCGAGACCTCCACTCATTCCATTTAAAGTCTGCGGGACGCGCCCAGTGGCGCCAGCAAGCTGCCCATG CAAAGCCGCAGCCTTTGGGAGGGAGAAGAGAAGGAAGAGCGCAGAGCCGGCAAAGTGAGATGCACGCCGTCCCGGCCCATAGACAAGTGG CGCTGGGGTTTCCCTCTCCCAGAACCGCTGCCACCACCGCCACGCCCTCCGCAGAAAGCCCACCTGGCCCTGTGGAACGTGTCGTCATTT GATTCTGTGCTTTTTGCTCCTTGTTTGTGGGGATCTGGGGATCAGCTGAAGGATCAGGAAGTGTGGGCTGTGCCCTAGCCACACCACAGC >66002_66002_4_PLCB4-RASA3_PLCB4_chr20_9424890_ENST00000334005_RASA3_chr13_114762215_ENST00000389544_length(amino acids)=1151AA_BP=961 MQSVQSCPVLNIIMAKPYEFNWQKEVPSFLQEGAVFDRYEEESFVFEPNCLFKVDEFGFFLTWRSEGKEGQVLECSLINSIRSGAIPKDP KILAALEAVGKSENDLEGRIVCVCSGTDLVNISFTYMVAENPEVTKQWVEGLRSIIHNFRANNVSPMTCLKKHWMKLAFMTNTNGKIPVR SITRTFASGKTEKVIFQALKELGLPSGKNDEIEPTAFSYEKFYELTQKICPRTDIEDLFKKINGDKTDYLTVDQLVSFLNEHQRDPRLNE ILFPFYDAKRAMQIIEMYEPDEDLKKKGLISSDGFCRYLMSDENAPVFLDRLELYQEMDHPLAHYFISSSHNTYLTGRQFGGKSSVEMYR QVLLAGCRCVELDCWDGKGEDQEPIITHGKAMCTDILFKDVIQAIKETAFVTSEYPVILSFENHCSKYQQYKMSKYCEDLFGDLLLKQAL ESHPLEPGRALPSPNDLKRKILIKNKRLKPEVEKKQLEALRSMMEAGESASPANILEDDNEEEIESADQEEEAHPEFKFGNELSADDLGH KEAVANSVKKGLVTVEDEQAWMASYKYVGATTNIHPYLSTMINYAQPVKFQGFHVAEERNIHYNMSSFNESVGLGYLKTHAIEFVNYNKR QMSRIYPKGGRVDSSNYMPQIFWNAGCQMVSLNYQTPDLAMQLNQGKFEYNGSCGYLLKPDFMRRPDRTFDPFSETPVDGVIAATCSVQV ISGQFLSDKKIGTYVEVDMYGLPTDTIRKEFRTRMVMNNGLNPVYNEESFVFRKVILPDLAVLRIAVYDDNNKLIGQRILPLDGLQAGYR HISLRNEGNKPLSLPTIFCNIVLKTYVPDGFGDIVDALSDPKKFLSITEKRADQMRAMGIETSDIADVPSDTSKNDKKGKANTAKANVTP QSSSELRPTTTAALASGVEAKKGIELIPQVRIEDLKQMKAYLKHLKKQQKELNSLKKKHAKMFQVIQPERALYIQANNCVEAKDWIDILT KVSQCNQKRLTVYHPSAYLSGHWLCCRAPSDSAPGCSPCTGGLPANIQLDIDGDRETERIYSLFNLYMSKLEKMQEACGSKSVYDGPEQE -------------------------------------------------------------- >66002_66002_5_PLCB4-RASA3_PLCB4_chr20_9424890_ENST00000378473_RASA3_chr13_114762215_ENST00000334062_length(transcript)=5248nt_BP=3111nt AGTAAGTGAGCTGCACCGCCAACAAGATCTCTCACACACAGACACACACACGCACACGCACACACGGGCGCGCACACACACGCGCGTACA CACTGGGTCTCCAGGCAGCGGCCGTCGCCGCATCCCCGGCAGCAGCTCCAGGCAAAGTGACAGAGGACAGTGCTGCTGTGAGTTTGACGA AGTGGACATCACCTGCAGTCAGTCCAGAGCTGCCCAGTCTTGAATATAATCATGGCCAAACCTTATGAATTTAACTGGCAGAAGGAAGTT CCCTCCTTTTTGCAAGAAGGAGCAGTTTTTGACAGATACGAGGAGGAATCCTTTGTGTTTGAACCCAACTGCCTCTTCAAAGTGGATGAG TTTGGCTTCTTTCTGACATGGAGAAGTGAAGGCAAGGAAGGACAGGTGCTAGAATGCTCCCTCATCAACAGTATTCGGTCGGGAGCCATA CCAAAGGATCCCAAAATCTTGGCTGCTCTTGAAGCTGTTGGAAAATCAGAAAATGATCTGGAAGGGCGGATAGTTTGTGTCTGCAGTGGC ACAGATCTAGTGAACATTAGTTTTACCTACATGGTGGCTGAAAATCCAGAAGTAACTAAGCAATGGGTAGAAGGCCTGAGATCAATCATA CACAACTTCAGGGCCAACAACGTCAGTCCAATGACATGCCTCAAGAAACACTGGATGAAATTGGCATTTATGACCAACACAAATGGTAAA ATTCCAGTTAGGAGTATTACTAGAACATTTGCATCGGGAAAAACAGAAAAGGTGATCTTTCAAGCACTCAAGGAGTTAGGTCTTCCCAGT GGAAAGAATGATGAAATTGAGCCCACAGCATTTTCTTATGAAAAGTTCTATGAACTGACACAAAAGATTTGTCCTCGGACAGATATAGAA GATCTTTTCAAAAAAATCAATGGAGACAAAACTGATTATTTAACGGTAGACCAATTAGTGAGCTTTCTAAATGAACATCAACGAGATCCT CGATTGAATGAAATTTTATTTCCATTTTATGATGCCAAAAGGGCAATGCAGATCATTGAGATGTATGAACCTGATGAAGATTTGAAGAAA AAAGGCCTTATATCAAGTGATGGGTTTTGCAGATATCTGATGTCAGATGAAAACGCCCCAGTCTTCCTAGATCGTTTAGAACTTTACCAA GAAATGGACCATCCTCTGGCTCACTACTTCATCAGTTCTTCCCATAACACTTATCTCACTGGCAGACAGTTCGGCGGGAAGTCTTCGGTA GAAATGTACAGACAGGTTCTCCTGGCTGGTTGCAGATGTGTTGAACTTGACTGCTGGGATGGAAAAGGTGAAGACCAAGAACCAATAATA ACTCATGGAAAAGCAATGTGTACAGATATCCTTTTTAAGGATGTAATTCAAGCCATCAAGGAAACTGCATTTGTCACATCAGAATATCCT GTAATTCTCTCCTTTGAAAATCACTGCAGCAAATATCAACAGTACAAGATGTCCAAATATTGCGAAGATCTATTTGGGGATCTCCTGTTG AAACAAGCACTTGAATCACATCCACTTGAACCAGGCAGGGCTTTGCCATCCCCCAATGACCTCAAAAGAAAAATACTCATAAAAAACAAG CGGCTGAAACCTGAAGTTGAAAAAAAACAGCTGGAAGCTTTGAGAAGCATGATGGAAGCTGGAGAATCTGCCTCCCCAGCAAACATCTTA GAGGACGATAATGAAGAGGAGATCGAAAGTGCTGACCAAGAGGAGGAAGCTCACCCCGAATTCAAATTTGGAAATGAACTTTCTGCTGAT GACTTGGGTCACAAGGAAGCTGTTGCAAATAGCGTCAAGAAGGCTTCAGATGACCTTGAACATGAAAACAACAAAAAGGGCCTGGTCACT GTAGAAGATGAGCAGGCGTGGATGGCATCTTATAAATATGTAGGTGCTACCACTAATATCCATCCATATTTGTCCACAATGATCAACTAC GCCCAGCCTGTAAAGTTTCAAGGTTTCCATGTGGCAGAAGAACGCAATATTCATTATAACATGTCTTCTTTTAATGAATCAGTCGGTCTT GGCTACTTGAAGACACATGCAATTGAATTTGTCAATTATAACAAACGGCAAATGAGTCGCATTTACCCCAAGGGAGGCCGAGTCGATTCC AGTAATTACATGCCTCAGATTTTCTGGAACGCTGGCTGCCAGATGGTTTCACTGAACTATCAAACCCCAGATTTAGCGATGCAATTGAAT CAGGGAAAATTTGAGTATAATGGATCGTGCGGGTACCTTCTCAAACCAGATTTCATGAGGCGGCCTGATCGAACATTTGACCCCTTCTCT GAAACTCCTGTTGATGGTGTTATTGCAGCCACTTGCTCAGTGCAGGTTATATCAGGTCAATTCTTATCAGATAAGAAAATTGGCACCTAC GTAGAGGTGGATATGTATGGGTTGCCCACTGACACCATACGTAAGGAATTCCGAACTCGCATGGTTATGAATAATGGACTCAATCCAGTT TACAATGAAGAGTCATTTGTATTTCGGAAGGTGATCCTGCCGGACCTGGCTGTCTTGAGAATAGCTGTGTATGATGATAACAACAAGCTG ATTGGCCAGAGGATCCTCCCGCTTGATGGCCTCCAAGCCGGATATCGACACATTTCCCTTCGAAATGAGGGAAATAAACCATTATCACTA CCAACAATTTTCTGCAATATTGTTCTTAAAACATATGTGCCTGATGGATTTGGAGATATCGTGGATGCTTTATCAGATCCAAAGAAATTT CTCTCAATTACAGAAAAGAGAGCAGACCAAATGAGAGCTATGGGCATTGAAACTAGTGACATAGCCGACGTGCCCAGTGACACTTCCAAA AATGACAAGAAAGGAAAGGCCAACACCGCCAAAGCAAATGTGACCCCTCAGAGTAGCTCTGAGCTCAGACCAACCACCACGGCTGCCCTG GCCTCTGGTGTGGAAGCCAAGAAAGGTATTGAACTTATCCCTCAAGTAAGGATAGAAGACTTAAAGCAGATGAAGGCTTACTTGAAGCAT TTAAAGAAACAGCAGAAGGAGCTAAATTCTTTAAAGAAGAAACATGCAAAGATGTTCCAGGTCATCCAGCCAGAGCGTGCGCTGTACATC CAGGCCAACAACTGCGTGGAGGCCAAGGACTGGATCGACATTCTCACCAAAGTGAGCCAGTGCAACCAGAAGCGCCTCACCGTCTACCAC CCGTCCGCCTACCTGAGCGGCCACTGGCTGTGCTGTAGGGCGCCATCCGACTCGGCTCCGGGCTGCTCGCCCTGCACTGGCGGCCTCCCA GCCAACATCCAGCTGGACATTGATGGGGACCGTGAGACGGAGCGTATCTACTCCCTCTTCAACTTGTACATGAGCAAGCTGGAGAAGATG CAGGAGGCCTGTGGGAGCAAATCTGTGTATGACGGCCCGGAGCAGGAGGAGTATTCGACGTTCGTCATTGACGACCCCCAGGAGACCTAC AAGACGCTAAAGCAAGTCATCGCTGGGGTTGGGGCTTTGGAGCAGGAGCACGCCCAGTATAAGAGGGACAAGTTCAAGAAGACGAAATAT GGAAGCCAGGAGCACCCCATCGGAGACAAGAGCTTCCAGAACTACATCCGGCAGCAGTCCGAGACCTCCACTCATTCCATTTAAAGTCTG CGGGACGCGCCCAGTGGCGCCAGCAAGCTGCCCATGCAAAGCCGCAGCCTTTGGGAGGGAGAAGAGAAGGAAGAGCGCAGAGCCGGCAAA GTGAGATGCACGCCGTCCCGGCCCATAGACAAGTGGCGCTGGGGTTTCCCTCTCCCAGAACCGCTGCCACCACCGCCACGCCCTCCGCAG AAAGCCCACCTGGCCCTGTGGAACGTGTCGTCATTTGATTCTGTGCTTTTTGCTCCTTGTTTGTGGGGATCTGGGGATCAGCTGAAGGAT CAGGAAGTGTGGGCTGTGCCCTAGCCACACCACAGCCAGCCTCAGGGAGCCACGGCCCGTCTAGTCGACTGTGACATGCACCTCCGGCCG TGTGTGCGTCAGTCTCGTGCACGTCTGTCTTGCGTGCACGGTGCGTGTGACGCTGGGCTCTGTGGCTCTGTGCCCGGGAGGCCTGCTGGC CCCGCCTCGGCTTTCGGCTTCATCACATTGGGAGGTTCAGAGCATTACTCTCCCACTGTGCCTGCCATCCAGGCAGCCATGGGAGGCGGC CTCCCTGTTCCACTTTCGAGGTTCGTTTGATTCCTGGCTGAGGGGTCAGTTTTATGGCTGGGAGGTGCAGAATTACACAGAAGTCCCAGT CTGAGGATGTCCTTGGTGCTTGGGGGATACGGGTTCTGTCCACAGAGTCCCTTGGAGGGAAAGGTGTGGGCTCCAGCTTCTCCAGGCGTC TGCGGAGCCCACAGTTGAAGCCCACATCGTTTTGCTGTTGAATGGGGTTTAAAATCAGAATTAACATTTGCCACCCCCCGTGGAAGTTTG AAGATTTTAAAAATAGAAATGTACATTTTTCAAGCTGTTTTTCTTTATGTTTTTGAAGGACCATTTTTAATTAGCTCTTTGATACAAAGT AACTCAGAACGTCAAAACCTATACCCACTAAAGGGAAGGCTGCCGGGAAGGCAAATGGAACAGGAATGGAGCCTGTCTCAGGAAGGCCAG CTGCAGGTCCTCCAGAAAATCAAAGAAGGGAAGAAACTCTGAGTTTGAGGTACAGGGGCTTCGGGGTGCAGACGTCCCTCCAGGGCCCAT GGTCAGTATTGCACCTGTGTTATGAACCCCCAGATGCTGTGCAGGGCAGGGGCGGGGGCTGCTGTTTTATTGGGGAGGGGAGCATCCTAA AAATGGGGTCCAGGCAGACCCCTCCAGACCTCACACTGCCGAGGAGGCCTTTCCCAAAGGGCGTCCTCCCGGGATGCAGACGGCAGGTGT GTGGGAAGCGCCGTTTAAATACACAGCACGACGTATCCTTGTACCGACTTCTCCCGGTTCTTGTTTGAAAATACTGTAGTTCAGGCTCTT GATCTAGATGGCAGATAGGAACTTTCTTGTCACAAAAATACTGGAGGAAAATGTTGTAAAAATAGACTTTTGGACACACAGCTGTTGGGG CTGCACTGAGCTGCAATTTTTAACATGGATTTATAACTTAATGTTTCTGTTTATAAAATACTAATGATTTGCAATGTATTTTACTGGCCA >66002_66002_5_PLCB4-RASA3_PLCB4_chr20_9424890_ENST00000378473_RASA3_chr13_114762215_ENST00000334062_length(amino acids)=1163AA_BP=973 MQSVQSCPVLNIIMAKPYEFNWQKEVPSFLQEGAVFDRYEEESFVFEPNCLFKVDEFGFFLTWRSEGKEGQVLECSLINSIRSGAIPKDP KILAALEAVGKSENDLEGRIVCVCSGTDLVNISFTYMVAENPEVTKQWVEGLRSIIHNFRANNVSPMTCLKKHWMKLAFMTNTNGKIPVR SITRTFASGKTEKVIFQALKELGLPSGKNDEIEPTAFSYEKFYELTQKICPRTDIEDLFKKINGDKTDYLTVDQLVSFLNEHQRDPRLNE ILFPFYDAKRAMQIIEMYEPDEDLKKKGLISSDGFCRYLMSDENAPVFLDRLELYQEMDHPLAHYFISSSHNTYLTGRQFGGKSSVEMYR QVLLAGCRCVELDCWDGKGEDQEPIITHGKAMCTDILFKDVIQAIKETAFVTSEYPVILSFENHCSKYQQYKMSKYCEDLFGDLLLKQAL ESHPLEPGRALPSPNDLKRKILIKNKRLKPEVEKKQLEALRSMMEAGESASPANILEDDNEEEIESADQEEEAHPEFKFGNELSADDLGH KEAVANSVKKASDDLEHENNKKGLVTVEDEQAWMASYKYVGATTNIHPYLSTMINYAQPVKFQGFHVAEERNIHYNMSSFNESVGLGYLK THAIEFVNYNKRQMSRIYPKGGRVDSSNYMPQIFWNAGCQMVSLNYQTPDLAMQLNQGKFEYNGSCGYLLKPDFMRRPDRTFDPFSETPV DGVIAATCSVQVISGQFLSDKKIGTYVEVDMYGLPTDTIRKEFRTRMVMNNGLNPVYNEESFVFRKVILPDLAVLRIAVYDDNNKLIGQR ILPLDGLQAGYRHISLRNEGNKPLSLPTIFCNIVLKTYVPDGFGDIVDALSDPKKFLSITEKRADQMRAMGIETSDIADVPSDTSKNDKK GKANTAKANVTPQSSSELRPTTTAALASGVEAKKGIELIPQVRIEDLKQMKAYLKHLKKQQKELNSLKKKHAKMFQVIQPERALYIQANN CVEAKDWIDILTKVSQCNQKRLTVYHPSAYLSGHWLCCRAPSDSAPGCSPCTGGLPANIQLDIDGDRETERIYSLFNLYMSKLEKMQEAC -------------------------------------------------------------- >66002_66002_6_PLCB4-RASA3_PLCB4_chr20_9424890_ENST00000378473_RASA3_chr13_114762215_ENST00000389544_length(transcript)=4004nt_BP=3111nt AGTAAGTGAGCTGCACCGCCAACAAGATCTCTCACACACAGACACACACACGCACACGCACACACGGGCGCGCACACACACGCGCGTACA CACTGGGTCTCCAGGCAGCGGCCGTCGCCGCATCCCCGGCAGCAGCTCCAGGCAAAGTGACAGAGGACAGTGCTGCTGTGAGTTTGACGA AGTGGACATCACCTGCAGTCAGTCCAGAGCTGCCCAGTCTTGAATATAATCATGGCCAAACCTTATGAATTTAACTGGCAGAAGGAAGTT CCCTCCTTTTTGCAAGAAGGAGCAGTTTTTGACAGATACGAGGAGGAATCCTTTGTGTTTGAACCCAACTGCCTCTTCAAAGTGGATGAG TTTGGCTTCTTTCTGACATGGAGAAGTGAAGGCAAGGAAGGACAGGTGCTAGAATGCTCCCTCATCAACAGTATTCGGTCGGGAGCCATA CCAAAGGATCCCAAAATCTTGGCTGCTCTTGAAGCTGTTGGAAAATCAGAAAATGATCTGGAAGGGCGGATAGTTTGTGTCTGCAGTGGC ACAGATCTAGTGAACATTAGTTTTACCTACATGGTGGCTGAAAATCCAGAAGTAACTAAGCAATGGGTAGAAGGCCTGAGATCAATCATA CACAACTTCAGGGCCAACAACGTCAGTCCAATGACATGCCTCAAGAAACACTGGATGAAATTGGCATTTATGACCAACACAAATGGTAAA ATTCCAGTTAGGAGTATTACTAGAACATTTGCATCGGGAAAAACAGAAAAGGTGATCTTTCAAGCACTCAAGGAGTTAGGTCTTCCCAGT GGAAAGAATGATGAAATTGAGCCCACAGCATTTTCTTATGAAAAGTTCTATGAACTGACACAAAAGATTTGTCCTCGGACAGATATAGAA GATCTTTTCAAAAAAATCAATGGAGACAAAACTGATTATTTAACGGTAGACCAATTAGTGAGCTTTCTAAATGAACATCAACGAGATCCT CGATTGAATGAAATTTTATTTCCATTTTATGATGCCAAAAGGGCAATGCAGATCATTGAGATGTATGAACCTGATGAAGATTTGAAGAAA AAAGGCCTTATATCAAGTGATGGGTTTTGCAGATATCTGATGTCAGATGAAAACGCCCCAGTCTTCCTAGATCGTTTAGAACTTTACCAA GAAATGGACCATCCTCTGGCTCACTACTTCATCAGTTCTTCCCATAACACTTATCTCACTGGCAGACAGTTCGGCGGGAAGTCTTCGGTA GAAATGTACAGACAGGTTCTCCTGGCTGGTTGCAGATGTGTTGAACTTGACTGCTGGGATGGAAAAGGTGAAGACCAAGAACCAATAATA ACTCATGGAAAAGCAATGTGTACAGATATCCTTTTTAAGGATGTAATTCAAGCCATCAAGGAAACTGCATTTGTCACATCAGAATATCCT GTAATTCTCTCCTTTGAAAATCACTGCAGCAAATATCAACAGTACAAGATGTCCAAATATTGCGAAGATCTATTTGGGGATCTCCTGTTG AAACAAGCACTTGAATCACATCCACTTGAACCAGGCAGGGCTTTGCCATCCCCCAATGACCTCAAAAGAAAAATACTCATAAAAAACAAG CGGCTGAAACCTGAAGTTGAAAAAAAACAGCTGGAAGCTTTGAGAAGCATGATGGAAGCTGGAGAATCTGCCTCCCCAGCAAACATCTTA GAGGACGATAATGAAGAGGAGATCGAAAGTGCTGACCAAGAGGAGGAAGCTCACCCCGAATTCAAATTTGGAAATGAACTTTCTGCTGAT GACTTGGGTCACAAGGAAGCTGTTGCAAATAGCGTCAAGAAGGCTTCAGATGACCTTGAACATGAAAACAACAAAAAGGGCCTGGTCACT GTAGAAGATGAGCAGGCGTGGATGGCATCTTATAAATATGTAGGTGCTACCACTAATATCCATCCATATTTGTCCACAATGATCAACTAC GCCCAGCCTGTAAAGTTTCAAGGTTTCCATGTGGCAGAAGAACGCAATATTCATTATAACATGTCTTCTTTTAATGAATCAGTCGGTCTT GGCTACTTGAAGACACATGCAATTGAATTTGTCAATTATAACAAACGGCAAATGAGTCGCATTTACCCCAAGGGAGGCCGAGTCGATTCC AGTAATTACATGCCTCAGATTTTCTGGAACGCTGGCTGCCAGATGGTTTCACTGAACTATCAAACCCCAGATTTAGCGATGCAATTGAAT CAGGGAAAATTTGAGTATAATGGATCGTGCGGGTACCTTCTCAAACCAGATTTCATGAGGCGGCCTGATCGAACATTTGACCCCTTCTCT GAAACTCCTGTTGATGGTGTTATTGCAGCCACTTGCTCAGTGCAGGTTATATCAGGTCAATTCTTATCAGATAAGAAAATTGGCACCTAC GTAGAGGTGGATATGTATGGGTTGCCCACTGACACCATACGTAAGGAATTCCGAACTCGCATGGTTATGAATAATGGACTCAATCCAGTT TACAATGAAGAGTCATTTGTATTTCGGAAGGTGATCCTGCCGGACCTGGCTGTCTTGAGAATAGCTGTGTATGATGATAACAACAAGCTG ATTGGCCAGAGGATCCTCCCGCTTGATGGCCTCCAAGCCGGATATCGACACATTTCCCTTCGAAATGAGGGAAATAAACCATTATCACTA CCAACAATTTTCTGCAATATTGTTCTTAAAACATATGTGCCTGATGGATTTGGAGATATCGTGGATGCTTTATCAGATCCAAAGAAATTT CTCTCAATTACAGAAAAGAGAGCAGACCAAATGAGAGCTATGGGCATTGAAACTAGTGACATAGCCGACGTGCCCAGTGACACTTCCAAA AATGACAAGAAAGGAAAGGCCAACACCGCCAAAGCAAATGTGACCCCTCAGAGTAGCTCTGAGCTCAGACCAACCACCACGGCTGCCCTG GCCTCTGGTGTGGAAGCCAAGAAAGGTATTGAACTTATCCCTCAAGTAAGGATAGAAGACTTAAAGCAGATGAAGGCTTACTTGAAGCAT TTAAAGAAACAGCAGAAGGAGCTAAATTCTTTAAAGAAGAAACATGCAAAGATGTTCCAGGTCATCCAGCCAGAGCGTGCGCTGTACATC CAGGCCAACAACTGCGTGGAGGCCAAGGACTGGATCGACATTCTCACCAAAGTGAGCCAGTGCAACCAGAAGCGCCTCACCGTCTACCAC CCGTCCGCCTACCTGAGCGGCCACTGGCTGTGCTGTAGGGCGCCATCCGACTCGGCTCCGGGCTGCTCGCCCTGCACTGGCGGCCTCCCA GCCAACATCCAGCTGGACATTGATGGGGACCGTGAGACGGAGCGTATCTACTCCCTCTTCAACTTGTACATGAGCAAGCTGGAGAAGATG CAGGAGGCCTGTGGGAGCAAATCTGTGTATGACGGCCCGGAGCAGGAGGAGTATTCGACGTTCGTCATTGACGACCCCCAGGAGACCTAC AAGACGCTAAAGCAAGTCATCGCTGGGGTTGGGGCTTTGGAGCAGGAGCACGCCCAGTATAAGAGGGACAAGTTCAAGAAGACGAAATAT GGAAGCCAGGAGCACCCCATCGGAGACAAGAGCTTCCAGAACTACATCCGGCAGCAGTCCGAGACCTCCACTCATTCCATTTAAAGTCTG CGGGACGCGCCCAGTGGCGCCAGCAAGCTGCCCATGCAAAGCCGCAGCCTTTGGGAGGGAGAAGAGAAGGAAGAGCGCAGAGCCGGCAAA GTGAGATGCACGCCGTCCCGGCCCATAGACAAGTGGCGCTGGGGTTTCCCTCTCCCAGAACCGCTGCCACCACCGCCACGCCCTCCGCAG AAAGCCCACCTGGCCCTGTGGAACGTGTCGTCATTTGATTCTGTGCTTTTTGCTCCTTGTTTGTGGGGATCTGGGGATCAGCTGAAGGAT >66002_66002_6_PLCB4-RASA3_PLCB4_chr20_9424890_ENST00000378473_RASA3_chr13_114762215_ENST00000389544_length(amino acids)=1163AA_BP=973 MQSVQSCPVLNIIMAKPYEFNWQKEVPSFLQEGAVFDRYEEESFVFEPNCLFKVDEFGFFLTWRSEGKEGQVLECSLINSIRSGAIPKDP KILAALEAVGKSENDLEGRIVCVCSGTDLVNISFTYMVAENPEVTKQWVEGLRSIIHNFRANNVSPMTCLKKHWMKLAFMTNTNGKIPVR SITRTFASGKTEKVIFQALKELGLPSGKNDEIEPTAFSYEKFYELTQKICPRTDIEDLFKKINGDKTDYLTVDQLVSFLNEHQRDPRLNE ILFPFYDAKRAMQIIEMYEPDEDLKKKGLISSDGFCRYLMSDENAPVFLDRLELYQEMDHPLAHYFISSSHNTYLTGRQFGGKSSVEMYR QVLLAGCRCVELDCWDGKGEDQEPIITHGKAMCTDILFKDVIQAIKETAFVTSEYPVILSFENHCSKYQQYKMSKYCEDLFGDLLLKQAL ESHPLEPGRALPSPNDLKRKILIKNKRLKPEVEKKQLEALRSMMEAGESASPANILEDDNEEEIESADQEEEAHPEFKFGNELSADDLGH KEAVANSVKKASDDLEHENNKKGLVTVEDEQAWMASYKYVGATTNIHPYLSTMINYAQPVKFQGFHVAEERNIHYNMSSFNESVGLGYLK THAIEFVNYNKRQMSRIYPKGGRVDSSNYMPQIFWNAGCQMVSLNYQTPDLAMQLNQGKFEYNGSCGYLLKPDFMRRPDRTFDPFSETPV DGVIAATCSVQVISGQFLSDKKIGTYVEVDMYGLPTDTIRKEFRTRMVMNNGLNPVYNEESFVFRKVILPDLAVLRIAVYDDNNKLIGQR ILPLDGLQAGYRHISLRNEGNKPLSLPTIFCNIVLKTYVPDGFGDIVDALSDPKKFLSITEKRADQMRAMGIETSDIADVPSDTSKNDKK GKANTAKANVTPQSSSELRPTTTAALASGVEAKKGIELIPQVRIEDLKQMKAYLKHLKKQQKELNSLKKKHAKMFQVIQPERALYIQANN CVEAKDWIDILTKVSQCNQKRLTVYHPSAYLSGHWLCCRAPSDSAPGCSPCTGGLPANIQLDIDGDRETERIYSLFNLYMSKLEKMQEAC -------------------------------------------------------------- >66002_66002_7_PLCB4-RASA3_PLCB4_chr20_9424890_ENST00000378493_RASA3_chr13_114762215_ENST00000334062_length(transcript)=4996nt_BP=2859nt GTCTTGAATATAATCATGGCCAAACCTTATGAATTTAACTGGCAGAAGGAAGTTCCCTCCTTTTTGCAAGAAGGAGCAGTTTTTGACAGA TACGAGGAGGAATCCTTTGTGTTTGAACCCAACTGCCTCTTCAAAGTGGATGAGTTTGGCTTCTTTCTGACATGGAGAAGTGAAGGCAAG GAAGGACAGGTGCTAGAATGCTCCCTCATCAACAGTATTCGGTCGGGAGCCATACCAAAGGATCCCAAAATCTTGGCTGCTCTTGAAGCT GTTGGAAAATCAGAAAATGATCTGGAAGGGCGGATAGTTTGTGTCTGCAGTGGCACAGATCTAGTGAACATTAGTTTTACCTACATGGTG GCTGAAAATCCAGAAGTAACTAAGCAATGGGTAGAAGGCCTGAGATCAATCATACACAACTTCAGGGCCAACAACGTCAGTCCAATGACA TGCCTCAAGAAACACTGGATGAAATTGGCATTTATGACCAACACAAATGGTAAAATTCCAGTTAGGAGTATTACTAGAACATTTGCATCG GGAAAAACAGAAAAGGTGATCTTTCAAGCACTCAAGGAGTTAGGTCTTCCCAGTGGAAAGAATGATGAAATTGAGCCCACAGCATTTTCT TATGAAAAGTTCTATGAACTGACACAAAAGATTTGTCCTCGGACAGATATAGAAGATCTTTTCAAAAAAATCAATGGAGACAAAACTGAT TATTTAACGGTAGACCAATTAGTGAGCTTTCTAAATGAACATCAACGAGATCCTCGATTGAATGAAATTTTATTTCCATTTTATGATGCC AAAAGGGCAATGCAGATCATTGAGATGTATGAACCTGATGAAGATTTGAAGAAAAAAGGCCTTATATCAAGTGATGGGTTTTGCAGATAT CTGATGTCAGATGAAAACGCCCCAGTCTTCCTAGATCGTTTAGAACTTTACCAAGAAATGGACCATCCTCTGGCTCACTACTTCATCAGT TCTTCCCATAACACTTATCTCACTGGCAGACAGTTCGGCGGGAAGTCTTCGGTAGAAATGTACAGACAGGTTCTCCTGGCTGGTTGCAGA TGTGTTGAACTTGACTGCTGGGATGGAAAAGGTGAAGACCAAGAACCAATAATAACTCATGGAAAAGCAATGTGTACAGATATCCTTTTT AAGGATGTAATTCAAGCCATCAAGGAAACTGCATTTGTCACATCAGAATATCCTGTAATTCTCTCCTTTGAAAATCACTGCAGCAAATAT CAACAGTACAAGATGTCCAAATATTGCGAAGATCTATTTGGGGATCTCCTGTTGAAACAAGCACTTGAATCACATCCACTTGAACCAGGC AGGGCTTTGCCATCCCCCAATGACCTCAAAAGAAAAATACTCATAAAAAACAAGCGGCTGAAACCTGAAGTTGAAAAAAAACAGCTGGAA GCTTTGAGAAGCATGATGGAAGCTGGAGAATCTGCCTCCCCAGCAAACATCTTAGAGGACGATAATGAAGAGGAGATCGAAAGTGCTGAC CAAGAGGAGGAAGCTCACCCCGAATTCAAATTTGGAAATGAACTTTCTGCTGATGACTTGGGTCACAAGGAAGCTGTTGCAAATAGCGTC AAGAAGGGCCTGGTCACTGTAGAAGATGAGCAGGCGTGGATGGCATCTTATAAATATGTAGGTGCTACCACTAATATCCATCCATATTTG TCCACAATGATCAACTACGCCCAGCCTGTAAAGTTTCAAGGTTTCCATGTGGCAGAAGAACGCAATATTCATTATAACATGTCTTCTTTT AATGAATCAGTCGGTCTTGGCTACTTGAAGACACATGCAATTGAATTTGTCAATTATAACAAACGGCAAATGAGTCGCATTTACCCCAAG GGAGGCCGAGTCGATTCCAGTAATTACATGCCTCAGATTTTCTGGAACGCTGGCTGCCAGATGGTTTCACTGAACTATCAAACCCCAGAT TTAGCGATGCAATTGAATCAGGGAAAATTTGAGTATAATGGATCGTGCGGGTACCTTCTCAAACCAGATTTCATGAGGCGGCCTGATCGA ACATTTGACCCCTTCTCTGAAACTCCTGTTGATGGTGTTATTGCAGCCACTTGCTCAGTGCAGGTTATATCAGGTCAATTCTTATCAGAT AAGAAAATTGGCACCTACGTAGAGGTGGATATGTATGGGTTGCCCACTGACACCATACGTAAGGAATTCCGAACTCGCATGGTTATGAAT AATGGACTCAATCCAGTTTACAATGAAGAGTCATTTGTATTTCGGAAGGTGATCCTGCCGGACCTGGCTGTCTTGAGAATAGCTGTGTAT GATGATAACAACAAGCTGATTGGCCAGAGGATCCTCCCGCTTGATGGCCTCCAAGCCGGATATCGACACATTTCCCTTCGAAATGAGGGA AATAAACCATTATCACTACCAACAATTTTCTGCAATATTGTTCTTAAAACATATGTGCCTGATGGATTTGGAGATATCGTGGATGCTTTA TCAGATCCAAAGAAATTTCTCTCAATTACAGAAAAGAGAGCAGACCAAATGAGAGCTATGGGCATTGAAACTAGTGACATAGCCGACGTG CCCAGTGACACTTCCAAAAATGACAAGAAAGGAAAGGCCAACACCGCCAAAGCAAATGTGACCCCTCAGAGTAGCTCTGAGCTCAGACCA ACCACCACGGCTGCCCTGGCCTCTGGTGTGGAAGCCAAGAAAGGTATTGAACTTATCCCTCAAGTAAGGATAGAAGACTTAAAGCAGATG AAGGCTTACTTGAAGCATTTAAAGAAACAGCAGAAGGAGCTAAATTCTTTAAAGAAGAAACATGCAAAGATGTTCCAGGTCATCCAGCCA GAGCGTGCGCTGTACATCCAGGCCAACAACTGCGTGGAGGCCAAGGACTGGATCGACATTCTCACCAAAGTGAGCCAGTGCAACCAGAAG CGCCTCACCGTCTACCACCCGTCCGCCTACCTGAGCGGCCACTGGCTGTGCTGTAGGGCGCCATCCGACTCGGCTCCGGGCTGCTCGCCC TGCACTGGCGGCCTCCCAGCCAACATCCAGCTGGACATTGATGGGGACCGTGAGACGGAGCGTATCTACTCCCTCTTCAACTTGTACATG AGCAAGCTGGAGAAGATGCAGGAGGCCTGTGGGAGCAAATCTGTGTATGACGGCCCGGAGCAGGAGGAGTATTCGACGTTCGTCATTGAC GACCCCCAGGAGACCTACAAGACGCTAAAGCAAGTCATCGCTGGGGTTGGGGCTTTGGAGCAGGAGCACGCCCAGTATAAGAGGGACAAG TTCAAGAAGACGAAATATGGAAGCCAGGAGCACCCCATCGGAGACAAGAGCTTCCAGAACTACATCCGGCAGCAGTCCGAGACCTCCACT CATTCCATTTAAAGTCTGCGGGACGCGCCCAGTGGCGCCAGCAAGCTGCCCATGCAAAGCCGCAGCCTTTGGGAGGGAGAAGAGAAGGAA GAGCGCAGAGCCGGCAAAGTGAGATGCACGCCGTCCCGGCCCATAGACAAGTGGCGCTGGGGTTTCCCTCTCCCAGAACCGCTGCCACCA CCGCCACGCCCTCCGCAGAAAGCCCACCTGGCCCTGTGGAACGTGTCGTCATTTGATTCTGTGCTTTTTGCTCCTTGTTTGTGGGGATCT GGGGATCAGCTGAAGGATCAGGAAGTGTGGGCTGTGCCCTAGCCACACCACAGCCAGCCTCAGGGAGCCACGGCCCGTCTAGTCGACTGT GACATGCACCTCCGGCCGTGTGTGCGTCAGTCTCGTGCACGTCTGTCTTGCGTGCACGGTGCGTGTGACGCTGGGCTCTGTGGCTCTGTG CCCGGGAGGCCTGCTGGCCCCGCCTCGGCTTTCGGCTTCATCACATTGGGAGGTTCAGAGCATTACTCTCCCACTGTGCCTGCCATCCAG GCAGCCATGGGAGGCGGCCTCCCTGTTCCACTTTCGAGGTTCGTTTGATTCCTGGCTGAGGGGTCAGTTTTATGGCTGGGAGGTGCAGAA TTACACAGAAGTCCCAGTCTGAGGATGTCCTTGGTGCTTGGGGGATACGGGTTCTGTCCACAGAGTCCCTTGGAGGGAAAGGTGTGGGCT CCAGCTTCTCCAGGCGTCTGCGGAGCCCACAGTTGAAGCCCACATCGTTTTGCTGTTGAATGGGGTTTAAAATCAGAATTAACATTTGCC ACCCCCCGTGGAAGTTTGAAGATTTTAAAAATAGAAATGTACATTTTTCAAGCTGTTTTTCTTTATGTTTTTGAAGGACCATTTTTAATT AGCTCTTTGATACAAAGTAACTCAGAACGTCAAAACCTATACCCACTAAAGGGAAGGCTGCCGGGAAGGCAAATGGAACAGGAATGGAGC CTGTCTCAGGAAGGCCAGCTGCAGGTCCTCCAGAAAATCAAAGAAGGGAAGAAACTCTGAGTTTGAGGTACAGGGGCTTCGGGGTGCAGA CGTCCCTCCAGGGCCCATGGTCAGTATTGCACCTGTGTTATGAACCCCCAGATGCTGTGCAGGGCAGGGGCGGGGGCTGCTGTTTTATTG GGGAGGGGAGCATCCTAAAAATGGGGTCCAGGCAGACCCCTCCAGACCTCACACTGCCGAGGAGGCCTTTCCCAAAGGGCGTCCTCCCGG GATGCAGACGGCAGGTGTGTGGGAAGCGCCGTTTAAATACACAGCACGACGTATCCTTGTACCGACTTCTCCCGGTTCTTGTTTGAAAAT ACTGTAGTTCAGGCTCTTGATCTAGATGGCAGATAGGAACTTTCTTGTCACAAAAATACTGGAGGAAAATGTTGTAAAAATAGACTTTTG GACACACAGCTGTTGGGGCTGCACTGAGCTGCAATTTTTAACATGGATTTATAACTTAATGTTTCTGTTTATAAAATACTAATGATTTGC >66002_66002_7_PLCB4-RASA3_PLCB4_chr20_9424890_ENST00000378493_RASA3_chr13_114762215_ENST00000334062_length(amino acids)=1142AA_BP=952 MNIIMAKPYEFNWQKEVPSFLQEGAVFDRYEEESFVFEPNCLFKVDEFGFFLTWRSEGKEGQVLECSLINSIRSGAIPKDPKILAALEAV GKSENDLEGRIVCVCSGTDLVNISFTYMVAENPEVTKQWVEGLRSIIHNFRANNVSPMTCLKKHWMKLAFMTNTNGKIPVRSITRTFASG KTEKVIFQALKELGLPSGKNDEIEPTAFSYEKFYELTQKICPRTDIEDLFKKINGDKTDYLTVDQLVSFLNEHQRDPRLNEILFPFYDAK RAMQIIEMYEPDEDLKKKGLISSDGFCRYLMSDENAPVFLDRLELYQEMDHPLAHYFISSSHNTYLTGRQFGGKSSVEMYRQVLLAGCRC VELDCWDGKGEDQEPIITHGKAMCTDILFKDVIQAIKETAFVTSEYPVILSFENHCSKYQQYKMSKYCEDLFGDLLLKQALESHPLEPGR ALPSPNDLKRKILIKNKRLKPEVEKKQLEALRSMMEAGESASPANILEDDNEEEIESADQEEEAHPEFKFGNELSADDLGHKEAVANSVK KGLVTVEDEQAWMASYKYVGATTNIHPYLSTMINYAQPVKFQGFHVAEERNIHYNMSSFNESVGLGYLKTHAIEFVNYNKRQMSRIYPKG GRVDSSNYMPQIFWNAGCQMVSLNYQTPDLAMQLNQGKFEYNGSCGYLLKPDFMRRPDRTFDPFSETPVDGVIAATCSVQVISGQFLSDK KIGTYVEVDMYGLPTDTIRKEFRTRMVMNNGLNPVYNEESFVFRKVILPDLAVLRIAVYDDNNKLIGQRILPLDGLQAGYRHISLRNEGN KPLSLPTIFCNIVLKTYVPDGFGDIVDALSDPKKFLSITEKRADQMRAMGIETSDIADVPSDTSKNDKKGKANTAKANVTPQSSSELRPT TTAALASGVEAKKGIELIPQVRIEDLKQMKAYLKHLKKQQKELNSLKKKHAKMFQVIQPERALYIQANNCVEAKDWIDILTKVSQCNQKR LTVYHPSAYLSGHWLCCRAPSDSAPGCSPCTGGLPANIQLDIDGDRETERIYSLFNLYMSKLEKMQEACGSKSVYDGPEQEEYSTFVIDD -------------------------------------------------------------- >66002_66002_8_PLCB4-RASA3_PLCB4_chr20_9424890_ENST00000378493_RASA3_chr13_114762215_ENST00000389544_length(transcript)=3752nt_BP=2859nt GTCTTGAATATAATCATGGCCAAACCTTATGAATTTAACTGGCAGAAGGAAGTTCCCTCCTTTTTGCAAGAAGGAGCAGTTTTTGACAGA TACGAGGAGGAATCCTTTGTGTTTGAACCCAACTGCCTCTTCAAAGTGGATGAGTTTGGCTTCTTTCTGACATGGAGAAGTGAAGGCAAG GAAGGACAGGTGCTAGAATGCTCCCTCATCAACAGTATTCGGTCGGGAGCCATACCAAAGGATCCCAAAATCTTGGCTGCTCTTGAAGCT GTTGGAAAATCAGAAAATGATCTGGAAGGGCGGATAGTTTGTGTCTGCAGTGGCACAGATCTAGTGAACATTAGTTTTACCTACATGGTG GCTGAAAATCCAGAAGTAACTAAGCAATGGGTAGAAGGCCTGAGATCAATCATACACAACTTCAGGGCCAACAACGTCAGTCCAATGACA TGCCTCAAGAAACACTGGATGAAATTGGCATTTATGACCAACACAAATGGTAAAATTCCAGTTAGGAGTATTACTAGAACATTTGCATCG GGAAAAACAGAAAAGGTGATCTTTCAAGCACTCAAGGAGTTAGGTCTTCCCAGTGGAAAGAATGATGAAATTGAGCCCACAGCATTTTCT TATGAAAAGTTCTATGAACTGACACAAAAGATTTGTCCTCGGACAGATATAGAAGATCTTTTCAAAAAAATCAATGGAGACAAAACTGAT TATTTAACGGTAGACCAATTAGTGAGCTTTCTAAATGAACATCAACGAGATCCTCGATTGAATGAAATTTTATTTCCATTTTATGATGCC AAAAGGGCAATGCAGATCATTGAGATGTATGAACCTGATGAAGATTTGAAGAAAAAAGGCCTTATATCAAGTGATGGGTTTTGCAGATAT CTGATGTCAGATGAAAACGCCCCAGTCTTCCTAGATCGTTTAGAACTTTACCAAGAAATGGACCATCCTCTGGCTCACTACTTCATCAGT TCTTCCCATAACACTTATCTCACTGGCAGACAGTTCGGCGGGAAGTCTTCGGTAGAAATGTACAGACAGGTTCTCCTGGCTGGTTGCAGA TGTGTTGAACTTGACTGCTGGGATGGAAAAGGTGAAGACCAAGAACCAATAATAACTCATGGAAAAGCAATGTGTACAGATATCCTTTTT AAGGATGTAATTCAAGCCATCAAGGAAACTGCATTTGTCACATCAGAATATCCTGTAATTCTCTCCTTTGAAAATCACTGCAGCAAATAT CAACAGTACAAGATGTCCAAATATTGCGAAGATCTATTTGGGGATCTCCTGTTGAAACAAGCACTTGAATCACATCCACTTGAACCAGGC AGGGCTTTGCCATCCCCCAATGACCTCAAAAGAAAAATACTCATAAAAAACAAGCGGCTGAAACCTGAAGTTGAAAAAAAACAGCTGGAA GCTTTGAGAAGCATGATGGAAGCTGGAGAATCTGCCTCCCCAGCAAACATCTTAGAGGACGATAATGAAGAGGAGATCGAAAGTGCTGAC CAAGAGGAGGAAGCTCACCCCGAATTCAAATTTGGAAATGAACTTTCTGCTGATGACTTGGGTCACAAGGAAGCTGTTGCAAATAGCGTC AAGAAGGGCCTGGTCACTGTAGAAGATGAGCAGGCGTGGATGGCATCTTATAAATATGTAGGTGCTACCACTAATATCCATCCATATTTG TCCACAATGATCAACTACGCCCAGCCTGTAAAGTTTCAAGGTTTCCATGTGGCAGAAGAACGCAATATTCATTATAACATGTCTTCTTTT AATGAATCAGTCGGTCTTGGCTACTTGAAGACACATGCAATTGAATTTGTCAATTATAACAAACGGCAAATGAGTCGCATTTACCCCAAG GGAGGCCGAGTCGATTCCAGTAATTACATGCCTCAGATTTTCTGGAACGCTGGCTGCCAGATGGTTTCACTGAACTATCAAACCCCAGAT TTAGCGATGCAATTGAATCAGGGAAAATTTGAGTATAATGGATCGTGCGGGTACCTTCTCAAACCAGATTTCATGAGGCGGCCTGATCGA ACATTTGACCCCTTCTCTGAAACTCCTGTTGATGGTGTTATTGCAGCCACTTGCTCAGTGCAGGTTATATCAGGTCAATTCTTATCAGAT AAGAAAATTGGCACCTACGTAGAGGTGGATATGTATGGGTTGCCCACTGACACCATACGTAAGGAATTCCGAACTCGCATGGTTATGAAT AATGGACTCAATCCAGTTTACAATGAAGAGTCATTTGTATTTCGGAAGGTGATCCTGCCGGACCTGGCTGTCTTGAGAATAGCTGTGTAT GATGATAACAACAAGCTGATTGGCCAGAGGATCCTCCCGCTTGATGGCCTCCAAGCCGGATATCGACACATTTCCCTTCGAAATGAGGGA AATAAACCATTATCACTACCAACAATTTTCTGCAATATTGTTCTTAAAACATATGTGCCTGATGGATTTGGAGATATCGTGGATGCTTTA TCAGATCCAAAGAAATTTCTCTCAATTACAGAAAAGAGAGCAGACCAAATGAGAGCTATGGGCATTGAAACTAGTGACATAGCCGACGTG CCCAGTGACACTTCCAAAAATGACAAGAAAGGAAAGGCCAACACCGCCAAAGCAAATGTGACCCCTCAGAGTAGCTCTGAGCTCAGACCA ACCACCACGGCTGCCCTGGCCTCTGGTGTGGAAGCCAAGAAAGGTATTGAACTTATCCCTCAAGTAAGGATAGAAGACTTAAAGCAGATG AAGGCTTACTTGAAGCATTTAAAGAAACAGCAGAAGGAGCTAAATTCTTTAAAGAAGAAACATGCAAAGATGTTCCAGGTCATCCAGCCA GAGCGTGCGCTGTACATCCAGGCCAACAACTGCGTGGAGGCCAAGGACTGGATCGACATTCTCACCAAAGTGAGCCAGTGCAACCAGAAG CGCCTCACCGTCTACCACCCGTCCGCCTACCTGAGCGGCCACTGGCTGTGCTGTAGGGCGCCATCCGACTCGGCTCCGGGCTGCTCGCCC TGCACTGGCGGCCTCCCAGCCAACATCCAGCTGGACATTGATGGGGACCGTGAGACGGAGCGTATCTACTCCCTCTTCAACTTGTACATG AGCAAGCTGGAGAAGATGCAGGAGGCCTGTGGGAGCAAATCTGTGTATGACGGCCCGGAGCAGGAGGAGTATTCGACGTTCGTCATTGAC GACCCCCAGGAGACCTACAAGACGCTAAAGCAAGTCATCGCTGGGGTTGGGGCTTTGGAGCAGGAGCACGCCCAGTATAAGAGGGACAAG TTCAAGAAGACGAAATATGGAAGCCAGGAGCACCCCATCGGAGACAAGAGCTTCCAGAACTACATCCGGCAGCAGTCCGAGACCTCCACT CATTCCATTTAAAGTCTGCGGGACGCGCCCAGTGGCGCCAGCAAGCTGCCCATGCAAAGCCGCAGCCTTTGGGAGGGAGAAGAGAAGGAA GAGCGCAGAGCCGGCAAAGTGAGATGCACGCCGTCCCGGCCCATAGACAAGTGGCGCTGGGGTTTCCCTCTCCCAGAACCGCTGCCACCA CCGCCACGCCCTCCGCAGAAAGCCCACCTGGCCCTGTGGAACGTGTCGTCATTTGATTCTGTGCTTTTTGCTCCTTGTTTGTGGGGATCT >66002_66002_8_PLCB4-RASA3_PLCB4_chr20_9424890_ENST00000378493_RASA3_chr13_114762215_ENST00000389544_length(amino acids)=1142AA_BP=952 MNIIMAKPYEFNWQKEVPSFLQEGAVFDRYEEESFVFEPNCLFKVDEFGFFLTWRSEGKEGQVLECSLINSIRSGAIPKDPKILAALEAV GKSENDLEGRIVCVCSGTDLVNISFTYMVAENPEVTKQWVEGLRSIIHNFRANNVSPMTCLKKHWMKLAFMTNTNGKIPVRSITRTFASG KTEKVIFQALKELGLPSGKNDEIEPTAFSYEKFYELTQKICPRTDIEDLFKKINGDKTDYLTVDQLVSFLNEHQRDPRLNEILFPFYDAK RAMQIIEMYEPDEDLKKKGLISSDGFCRYLMSDENAPVFLDRLELYQEMDHPLAHYFISSSHNTYLTGRQFGGKSSVEMYRQVLLAGCRC VELDCWDGKGEDQEPIITHGKAMCTDILFKDVIQAIKETAFVTSEYPVILSFENHCSKYQQYKMSKYCEDLFGDLLLKQALESHPLEPGR ALPSPNDLKRKILIKNKRLKPEVEKKQLEALRSMMEAGESASPANILEDDNEEEIESADQEEEAHPEFKFGNELSADDLGHKEAVANSVK KGLVTVEDEQAWMASYKYVGATTNIHPYLSTMINYAQPVKFQGFHVAEERNIHYNMSSFNESVGLGYLKTHAIEFVNYNKRQMSRIYPKG GRVDSSNYMPQIFWNAGCQMVSLNYQTPDLAMQLNQGKFEYNGSCGYLLKPDFMRRPDRTFDPFSETPVDGVIAATCSVQVISGQFLSDK KIGTYVEVDMYGLPTDTIRKEFRTRMVMNNGLNPVYNEESFVFRKVILPDLAVLRIAVYDDNNKLIGQRILPLDGLQAGYRHISLRNEGN KPLSLPTIFCNIVLKTYVPDGFGDIVDALSDPKKFLSITEKRADQMRAMGIETSDIADVPSDTSKNDKKGKANTAKANVTPQSSSELRPT TTAALASGVEAKKGIELIPQVRIEDLKQMKAYLKHLKKQQKELNSLKKKHAKMFQVIQPERALYIQANNCVEAKDWIDILTKVSQCNQKR LTVYHPSAYLSGHWLCCRAPSDSAPGCSPCTGGLPANIQLDIDGDRETERIYSLFNLYMSKLEKMQEACGSKSVYDGPEQEEYSTFVIDD -------------------------------------------------------------- >66002_66002_9_PLCB4-RASA3_PLCB4_chr20_9424890_ENST00000378501_RASA3_chr13_114762215_ENST00000334062_length(transcript)=4996nt_BP=2859nt GTCTTGAATATAATCATGGCCAAACCTTATGAATTTAACTGGCAGAAGGAAGTTCCCTCCTTTTTGCAAGAAGGAGCAGTTTTTGACAGA TACGAGGAGGAATCCTTTGTGTTTGAACCCAACTGCCTCTTCAAAGTGGATGAGTTTGGCTTCTTTCTGACATGGAGAAGTGAAGGCAAG GAAGGACAGGTGCTAGAATGCTCCCTCATCAACAGTATTCGGTCGGGAGCCATACCAAAGGATCCCAAAATCTTGGCTGCTCTTGAAGCT GTTGGAAAATCAGAAAATGATCTGGAAGGGCGGATAGTTTGTGTCTGCAGTGGCACAGATCTAGTGAACATTAGTTTTACCTACATGGTG GCTGAAAATCCAGAAGTAACTAAGCAATGGGTAGAAGGCCTGAGATCAATCATACACAACTTCAGGGCCAACAACGTCAGTCCAATGACA TGCCTCAAGAAACACTGGATGAAATTGGCATTTATGACCAACACAAATGGTAAAATTCCAGTTAGGAGTATTACTAGAACATTTGCATCG GGAAAAACAGAAAAGGTGATCTTTCAAGCACTCAAGGAGTTAGGTCTTCCCAGTGGAAAGAATGATGAAATTGAGCCCACAGCATTTTCT TATGAAAAGTTCTATGAACTGACACAAAAGATTTGTCCTCGGACAGATATAGAAGATCTTTTCAAAAAAATCAATGGAGACAAAACTGAT TATTTAACGGTAGACCAATTAGTGAGCTTTCTAAATGAACATCAACGAGATCCTCGATTGAATGAAATTTTATTTCCATTTTATGATGCC AAAAGGGCAATGCAGATCATTGAGATGTATGAACCTGATGAAGATTTGAAGAAAAAAGGCCTTATATCAAGTGATGGGTTTTGCAGATAT CTGATGTCAGATGAAAACGCCCCAGTCTTCCTAGATCGTTTAGAACTTTACCAAGAAATGGACCATCCTCTGGCTCACTACTTCATCAGT TCTTCCCATAACACTTATCTCACTGGCAGACAGTTCGGCGGGAAGTCTTCGGTAGAAATGTACAGACAGGTTCTCCTGGCTGGTTGCAGA TGTGTTGAACTTGACTGCTGGGATGGAAAAGGTGAAGACCAAGAACCAATAATAACTCATGGAAAAGCAATGTGTACAGATATCCTTTTT AAGGATGTAATTCAAGCCATCAAGGAAACTGCATTTGTCACATCAGAATATCCTGTAATTCTCTCCTTTGAAAATCACTGCAGCAAATAT CAACAGTACAAGATGTCCAAATATTGCGAAGATCTATTTGGGGATCTCCTGTTGAAACAAGCACTTGAATCACATCCACTTGAACCAGGC AGGGCTTTGCCATCCCCCAATGACCTCAAAAGAAAAATACTCATAAAAAACAAGCGGCTGAAACCTGAAGTTGAAAAAAAACAGCTGGAA GCTTTGAGAAGCATGATGGAAGCTGGAGAATCTGCCTCCCCAGCAAACATCTTAGAGGACGATAATGAAGAGGAGATCGAAAGTGCTGAC CAAGAGGAGGAAGCTCACCCCGAATTCAAATTTGGAAATGAACTTTCTGCTGATGACTTGGGTCACAAGGAAGCTGTTGCAAATAGCGTC AAGAAGGGCCTGGTCACTGTAGAAGATGAGCAGGCGTGGATGGCATCTTATAAATATGTAGGTGCTACCACTAATATCCATCCATATTTG TCCACAATGATCAACTACGCCCAGCCTGTAAAGTTTCAAGGTTTCCATGTGGCAGAAGAACGCAATATTCATTATAACATGTCTTCTTTT AATGAATCAGTCGGTCTTGGCTACTTGAAGACACATGCAATTGAATTTGTCAATTATAACAAACGGCAAATGAGTCGCATTTACCCCAAG GGAGGCCGAGTCGATTCCAGTAATTACATGCCTCAGATTTTCTGGAACGCTGGCTGCCAGATGGTTTCACTGAACTATCAAACCCCAGAT TTAGCGATGCAATTGAATCAGGGAAAATTTGAGTATAATGGATCGTGCGGGTACCTTCTCAAACCAGATTTCATGAGGCGGCCTGATCGA ACATTTGACCCCTTCTCTGAAACTCCTGTTGATGGTGTTATTGCAGCCACTTGCTCAGTGCAGGTTATATCAGGTCAATTCTTATCAGAT AAGAAAATTGGCACCTACGTAGAGGTGGATATGTATGGGTTGCCCACTGACACCATACGTAAGGAATTCCGAACTCGCATGGTTATGAAT AATGGACTCAATCCAGTTTACAATGAAGAGTCATTTGTATTTCGGAAGGTGATCCTGCCGGACCTGGCTGTCTTGAGAATAGCTGTGTAT GATGATAACAACAAGCTGATTGGCCAGAGGATCCTCCCGCTTGATGGCCTCCAAGCCGGATATCGACACATTTCCCTTCGAAATGAGGGA AATAAACCATTATCACTACCAACAATTTTCTGCAATATTGTTCTTAAAACATATGTGCCTGATGGATTTGGAGATATCGTGGATGCTTTA TCAGATCCAAAGAAATTTCTCTCAATTACAGAAAAGAGAGCAGACCAAATGAGAGCTATGGGCATTGAAACTAGTGACATAGCCGACGTG CCCAGTGACACTTCCAAAAATGACAAGAAAGGAAAGGCCAACACCGCCAAAGCAAATGTGACCCCTCAGAGTAGCTCTGAGCTCAGACCA ACCACCACGGCTGCCCTGGCCTCTGGTGTGGAAGCCAAGAAAGGTATTGAACTTATCCCTCAAGTAAGGATAGAAGACTTAAAGCAGATG AAGGCTTACTTGAAGCATTTAAAGAAACAGCAGAAGGAGCTAAATTCTTTAAAGAAGAAACATGCAAAGATGTTCCAGGTCATCCAGCCA GAGCGTGCGCTGTACATCCAGGCCAACAACTGCGTGGAGGCCAAGGACTGGATCGACATTCTCACCAAAGTGAGCCAGTGCAACCAGAAG CGCCTCACCGTCTACCACCCGTCCGCCTACCTGAGCGGCCACTGGCTGTGCTGTAGGGCGCCATCCGACTCGGCTCCGGGCTGCTCGCCC TGCACTGGCGGCCTCCCAGCCAACATCCAGCTGGACATTGATGGGGACCGTGAGACGGAGCGTATCTACTCCCTCTTCAACTTGTACATG AGCAAGCTGGAGAAGATGCAGGAGGCCTGTGGGAGCAAATCTGTGTATGACGGCCCGGAGCAGGAGGAGTATTCGACGTTCGTCATTGAC GACCCCCAGGAGACCTACAAGACGCTAAAGCAAGTCATCGCTGGGGTTGGGGCTTTGGAGCAGGAGCACGCCCAGTATAAGAGGGACAAG TTCAAGAAGACGAAATATGGAAGCCAGGAGCACCCCATCGGAGACAAGAGCTTCCAGAACTACATCCGGCAGCAGTCCGAGACCTCCACT CATTCCATTTAAAGTCTGCGGGACGCGCCCAGTGGCGCCAGCAAGCTGCCCATGCAAAGCCGCAGCCTTTGGGAGGGAGAAGAGAAGGAA GAGCGCAGAGCCGGCAAAGTGAGATGCACGCCGTCCCGGCCCATAGACAAGTGGCGCTGGGGTTTCCCTCTCCCAGAACCGCTGCCACCA CCGCCACGCCCTCCGCAGAAAGCCCACCTGGCCCTGTGGAACGTGTCGTCATTTGATTCTGTGCTTTTTGCTCCTTGTTTGTGGGGATCT GGGGATCAGCTGAAGGATCAGGAAGTGTGGGCTGTGCCCTAGCCACACCACAGCCAGCCTCAGGGAGCCACGGCCCGTCTAGTCGACTGT GACATGCACCTCCGGCCGTGTGTGCGTCAGTCTCGTGCACGTCTGTCTTGCGTGCACGGTGCGTGTGACGCTGGGCTCTGTGGCTCTGTG CCCGGGAGGCCTGCTGGCCCCGCCTCGGCTTTCGGCTTCATCACATTGGGAGGTTCAGAGCATTACTCTCCCACTGTGCCTGCCATCCAG GCAGCCATGGGAGGCGGCCTCCCTGTTCCACTTTCGAGGTTCGTTTGATTCCTGGCTGAGGGGTCAGTTTTATGGCTGGGAGGTGCAGAA TTACACAGAAGTCCCAGTCTGAGGATGTCCTTGGTGCTTGGGGGATACGGGTTCTGTCCACAGAGTCCCTTGGAGGGAAAGGTGTGGGCT CCAGCTTCTCCAGGCGTCTGCGGAGCCCACAGTTGAAGCCCACATCGTTTTGCTGTTGAATGGGGTTTAAAATCAGAATTAACATTTGCC ACCCCCCGTGGAAGTTTGAAGATTTTAAAAATAGAAATGTACATTTTTCAAGCTGTTTTTCTTTATGTTTTTGAAGGACCATTTTTAATT AGCTCTTTGATACAAAGTAACTCAGAACGTCAAAACCTATACCCACTAAAGGGAAGGCTGCCGGGAAGGCAAATGGAACAGGAATGGAGC CTGTCTCAGGAAGGCCAGCTGCAGGTCCTCCAGAAAATCAAAGAAGGGAAGAAACTCTGAGTTTGAGGTACAGGGGCTTCGGGGTGCAGA CGTCCCTCCAGGGCCCATGGTCAGTATTGCACCTGTGTTATGAACCCCCAGATGCTGTGCAGGGCAGGGGCGGGGGCTGCTGTTTTATTG GGGAGGGGAGCATCCTAAAAATGGGGTCCAGGCAGACCCCTCCAGACCTCACACTGCCGAGGAGGCCTTTCCCAAAGGGCGTCCTCCCGG GATGCAGACGGCAGGTGTGTGGGAAGCGCCGTTTAAATACACAGCACGACGTATCCTTGTACCGACTTCTCCCGGTTCTTGTTTGAAAAT ACTGTAGTTCAGGCTCTTGATCTAGATGGCAGATAGGAACTTTCTTGTCACAAAAATACTGGAGGAAAATGTTGTAAAAATAGACTTTTG GACACACAGCTGTTGGGGCTGCACTGAGCTGCAATTTTTAACATGGATTTATAACTTAATGTTTCTGTTTATAAAATACTAATGATTTGC >66002_66002_9_PLCB4-RASA3_PLCB4_chr20_9424890_ENST00000378501_RASA3_chr13_114762215_ENST00000334062_length(amino acids)=1142AA_BP=952 MNIIMAKPYEFNWQKEVPSFLQEGAVFDRYEEESFVFEPNCLFKVDEFGFFLTWRSEGKEGQVLECSLINSIRSGAIPKDPKILAALEAV GKSENDLEGRIVCVCSGTDLVNISFTYMVAENPEVTKQWVEGLRSIIHNFRANNVSPMTCLKKHWMKLAFMTNTNGKIPVRSITRTFASG KTEKVIFQALKELGLPSGKNDEIEPTAFSYEKFYELTQKICPRTDIEDLFKKINGDKTDYLTVDQLVSFLNEHQRDPRLNEILFPFYDAK RAMQIIEMYEPDEDLKKKGLISSDGFCRYLMSDENAPVFLDRLELYQEMDHPLAHYFISSSHNTYLTGRQFGGKSSVEMYRQVLLAGCRC VELDCWDGKGEDQEPIITHGKAMCTDILFKDVIQAIKETAFVTSEYPVILSFENHCSKYQQYKMSKYCEDLFGDLLLKQALESHPLEPGR ALPSPNDLKRKILIKNKRLKPEVEKKQLEALRSMMEAGESASPANILEDDNEEEIESADQEEEAHPEFKFGNELSADDLGHKEAVANSVK KGLVTVEDEQAWMASYKYVGATTNIHPYLSTMINYAQPVKFQGFHVAEERNIHYNMSSFNESVGLGYLKTHAIEFVNYNKRQMSRIYPKG GRVDSSNYMPQIFWNAGCQMVSLNYQTPDLAMQLNQGKFEYNGSCGYLLKPDFMRRPDRTFDPFSETPVDGVIAATCSVQVISGQFLSDK KIGTYVEVDMYGLPTDTIRKEFRTRMVMNNGLNPVYNEESFVFRKVILPDLAVLRIAVYDDNNKLIGQRILPLDGLQAGYRHISLRNEGN KPLSLPTIFCNIVLKTYVPDGFGDIVDALSDPKKFLSITEKRADQMRAMGIETSDIADVPSDTSKNDKKGKANTAKANVTPQSSSELRPT TTAALASGVEAKKGIELIPQVRIEDLKQMKAYLKHLKKQQKELNSLKKKHAKMFQVIQPERALYIQANNCVEAKDWIDILTKVSQCNQKR LTVYHPSAYLSGHWLCCRAPSDSAPGCSPCTGGLPANIQLDIDGDRETERIYSLFNLYMSKLEKMQEACGSKSVYDGPEQEEYSTFVIDD -------------------------------------------------------------- >66002_66002_10_PLCB4-RASA3_PLCB4_chr20_9424890_ENST00000378501_RASA3_chr13_114762215_ENST00000389544_length(transcript)=3752nt_BP=2859nt GTCTTGAATATAATCATGGCCAAACCTTATGAATTTAACTGGCAGAAGGAAGTTCCCTCCTTTTTGCAAGAAGGAGCAGTTTTTGACAGA TACGAGGAGGAATCCTTTGTGTTTGAACCCAACTGCCTCTTCAAAGTGGATGAGTTTGGCTTCTTTCTGACATGGAGAAGTGAAGGCAAG GAAGGACAGGTGCTAGAATGCTCCCTCATCAACAGTATTCGGTCGGGAGCCATACCAAAGGATCCCAAAATCTTGGCTGCTCTTGAAGCT GTTGGAAAATCAGAAAATGATCTGGAAGGGCGGATAGTTTGTGTCTGCAGTGGCACAGATCTAGTGAACATTAGTTTTACCTACATGGTG GCTGAAAATCCAGAAGTAACTAAGCAATGGGTAGAAGGCCTGAGATCAATCATACACAACTTCAGGGCCAACAACGTCAGTCCAATGACA TGCCTCAAGAAACACTGGATGAAATTGGCATTTATGACCAACACAAATGGTAAAATTCCAGTTAGGAGTATTACTAGAACATTTGCATCG GGAAAAACAGAAAAGGTGATCTTTCAAGCACTCAAGGAGTTAGGTCTTCCCAGTGGAAAGAATGATGAAATTGAGCCCACAGCATTTTCT TATGAAAAGTTCTATGAACTGACACAAAAGATTTGTCCTCGGACAGATATAGAAGATCTTTTCAAAAAAATCAATGGAGACAAAACTGAT TATTTAACGGTAGACCAATTAGTGAGCTTTCTAAATGAACATCAACGAGATCCTCGATTGAATGAAATTTTATTTCCATTTTATGATGCC AAAAGGGCAATGCAGATCATTGAGATGTATGAACCTGATGAAGATTTGAAGAAAAAAGGCCTTATATCAAGTGATGGGTTTTGCAGATAT CTGATGTCAGATGAAAACGCCCCAGTCTTCCTAGATCGTTTAGAACTTTACCAAGAAATGGACCATCCTCTGGCTCACTACTTCATCAGT TCTTCCCATAACACTTATCTCACTGGCAGACAGTTCGGCGGGAAGTCTTCGGTAGAAATGTACAGACAGGTTCTCCTGGCTGGTTGCAGA TGTGTTGAACTTGACTGCTGGGATGGAAAAGGTGAAGACCAAGAACCAATAATAACTCATGGAAAAGCAATGTGTACAGATATCCTTTTT AAGGATGTAATTCAAGCCATCAAGGAAACTGCATTTGTCACATCAGAATATCCTGTAATTCTCTCCTTTGAAAATCACTGCAGCAAATAT CAACAGTACAAGATGTCCAAATATTGCGAAGATCTATTTGGGGATCTCCTGTTGAAACAAGCACTTGAATCACATCCACTTGAACCAGGC AGGGCTTTGCCATCCCCCAATGACCTCAAAAGAAAAATACTCATAAAAAACAAGCGGCTGAAACCTGAAGTTGAAAAAAAACAGCTGGAA GCTTTGAGAAGCATGATGGAAGCTGGAGAATCTGCCTCCCCAGCAAACATCTTAGAGGACGATAATGAAGAGGAGATCGAAAGTGCTGAC CAAGAGGAGGAAGCTCACCCCGAATTCAAATTTGGAAATGAACTTTCTGCTGATGACTTGGGTCACAAGGAAGCTGTTGCAAATAGCGTC AAGAAGGGCCTGGTCACTGTAGAAGATGAGCAGGCGTGGATGGCATCTTATAAATATGTAGGTGCTACCACTAATATCCATCCATATTTG TCCACAATGATCAACTACGCCCAGCCTGTAAAGTTTCAAGGTTTCCATGTGGCAGAAGAACGCAATATTCATTATAACATGTCTTCTTTT AATGAATCAGTCGGTCTTGGCTACTTGAAGACACATGCAATTGAATTTGTCAATTATAACAAACGGCAAATGAGTCGCATTTACCCCAAG GGAGGCCGAGTCGATTCCAGTAATTACATGCCTCAGATTTTCTGGAACGCTGGCTGCCAGATGGTTTCACTGAACTATCAAACCCCAGAT TTAGCGATGCAATTGAATCAGGGAAAATTTGAGTATAATGGATCGTGCGGGTACCTTCTCAAACCAGATTTCATGAGGCGGCCTGATCGA ACATTTGACCCCTTCTCTGAAACTCCTGTTGATGGTGTTATTGCAGCCACTTGCTCAGTGCAGGTTATATCAGGTCAATTCTTATCAGAT AAGAAAATTGGCACCTACGTAGAGGTGGATATGTATGGGTTGCCCACTGACACCATACGTAAGGAATTCCGAACTCGCATGGTTATGAAT AATGGACTCAATCCAGTTTACAATGAAGAGTCATTTGTATTTCGGAAGGTGATCCTGCCGGACCTGGCTGTCTTGAGAATAGCTGTGTAT GATGATAACAACAAGCTGATTGGCCAGAGGATCCTCCCGCTTGATGGCCTCCAAGCCGGATATCGACACATTTCCCTTCGAAATGAGGGA AATAAACCATTATCACTACCAACAATTTTCTGCAATATTGTTCTTAAAACATATGTGCCTGATGGATTTGGAGATATCGTGGATGCTTTA TCAGATCCAAAGAAATTTCTCTCAATTACAGAAAAGAGAGCAGACCAAATGAGAGCTATGGGCATTGAAACTAGTGACATAGCCGACGTG CCCAGTGACACTTCCAAAAATGACAAGAAAGGAAAGGCCAACACCGCCAAAGCAAATGTGACCCCTCAGAGTAGCTCTGAGCTCAGACCA ACCACCACGGCTGCCCTGGCCTCTGGTGTGGAAGCCAAGAAAGGTATTGAACTTATCCCTCAAGTAAGGATAGAAGACTTAAAGCAGATG AAGGCTTACTTGAAGCATTTAAAGAAACAGCAGAAGGAGCTAAATTCTTTAAAGAAGAAACATGCAAAGATGTTCCAGGTCATCCAGCCA GAGCGTGCGCTGTACATCCAGGCCAACAACTGCGTGGAGGCCAAGGACTGGATCGACATTCTCACCAAAGTGAGCCAGTGCAACCAGAAG CGCCTCACCGTCTACCACCCGTCCGCCTACCTGAGCGGCCACTGGCTGTGCTGTAGGGCGCCATCCGACTCGGCTCCGGGCTGCTCGCCC TGCACTGGCGGCCTCCCAGCCAACATCCAGCTGGACATTGATGGGGACCGTGAGACGGAGCGTATCTACTCCCTCTTCAACTTGTACATG AGCAAGCTGGAGAAGATGCAGGAGGCCTGTGGGAGCAAATCTGTGTATGACGGCCCGGAGCAGGAGGAGTATTCGACGTTCGTCATTGAC GACCCCCAGGAGACCTACAAGACGCTAAAGCAAGTCATCGCTGGGGTTGGGGCTTTGGAGCAGGAGCACGCCCAGTATAAGAGGGACAAG TTCAAGAAGACGAAATATGGAAGCCAGGAGCACCCCATCGGAGACAAGAGCTTCCAGAACTACATCCGGCAGCAGTCCGAGACCTCCACT CATTCCATTTAAAGTCTGCGGGACGCGCCCAGTGGCGCCAGCAAGCTGCCCATGCAAAGCCGCAGCCTTTGGGAGGGAGAAGAGAAGGAA GAGCGCAGAGCCGGCAAAGTGAGATGCACGCCGTCCCGGCCCATAGACAAGTGGCGCTGGGGTTTCCCTCTCCCAGAACCGCTGCCACCA CCGCCACGCCCTCCGCAGAAAGCCCACCTGGCCCTGTGGAACGTGTCGTCATTTGATTCTGTGCTTTTTGCTCCTTGTTTGTGGGGATCT >66002_66002_10_PLCB4-RASA3_PLCB4_chr20_9424890_ENST00000378501_RASA3_chr13_114762215_ENST00000389544_length(amino acids)=1142AA_BP=952 MNIIMAKPYEFNWQKEVPSFLQEGAVFDRYEEESFVFEPNCLFKVDEFGFFLTWRSEGKEGQVLECSLINSIRSGAIPKDPKILAALEAV GKSENDLEGRIVCVCSGTDLVNISFTYMVAENPEVTKQWVEGLRSIIHNFRANNVSPMTCLKKHWMKLAFMTNTNGKIPVRSITRTFASG KTEKVIFQALKELGLPSGKNDEIEPTAFSYEKFYELTQKICPRTDIEDLFKKINGDKTDYLTVDQLVSFLNEHQRDPRLNEILFPFYDAK RAMQIIEMYEPDEDLKKKGLISSDGFCRYLMSDENAPVFLDRLELYQEMDHPLAHYFISSSHNTYLTGRQFGGKSSVEMYRQVLLAGCRC VELDCWDGKGEDQEPIITHGKAMCTDILFKDVIQAIKETAFVTSEYPVILSFENHCSKYQQYKMSKYCEDLFGDLLLKQALESHPLEPGR ALPSPNDLKRKILIKNKRLKPEVEKKQLEALRSMMEAGESASPANILEDDNEEEIESADQEEEAHPEFKFGNELSADDLGHKEAVANSVK KGLVTVEDEQAWMASYKYVGATTNIHPYLSTMINYAQPVKFQGFHVAEERNIHYNMSSFNESVGLGYLKTHAIEFVNYNKRQMSRIYPKG GRVDSSNYMPQIFWNAGCQMVSLNYQTPDLAMQLNQGKFEYNGSCGYLLKPDFMRRPDRTFDPFSETPVDGVIAATCSVQVISGQFLSDK KIGTYVEVDMYGLPTDTIRKEFRTRMVMNNGLNPVYNEESFVFRKVILPDLAVLRIAVYDDNNKLIGQRILPLDGLQAGYRHISLRNEGN KPLSLPTIFCNIVLKTYVPDGFGDIVDALSDPKKFLSITEKRADQMRAMGIETSDIADVPSDTSKNDKKGKANTAKANVTPQSSSELRPT TTAALASGVEAKKGIELIPQVRIEDLKQMKAYLKHLKKQQKELNSLKKKHAKMFQVIQPERALYIQANNCVEAKDWIDILTKVSQCNQKR LTVYHPSAYLSGHWLCCRAPSDSAPGCSPCTGGLPANIQLDIDGDRETERIYSLFNLYMSKLEKMQEACGSKSVYDGPEQEEYSTFVIDD -------------------------------------------------------------- >66002_66002_11_PLCB4-RASA3_PLCB4_chr20_9424890_ENST00000414679_RASA3_chr13_114762215_ENST00000334062_length(transcript)=5032nt_BP=2895nt GTCTTGAATATAATCATGGCCAAACCTTATGAATTTAACTGGCAGAAGGAAGTTCCCTCCTTTTTGCAAGAAGGAGCAGTTTTTGACAGA TACGAGGAGGAATCCTTTGTGTTTGAACCCAACTGCCTCTTCAAAGTGGATGAGTTTGGCTTCTTTCTGACATGGAGAAGTGAAGGCAAG GAAGGACAGGTGCTAGAATGCTCCCTCATCAACAGTATTCGGTCGGGAGCCATACCAAAGGATCCCAAAATCTTGGCTGCTCTTGAAGCT GTTGGAAAATCAGAAAATGATCTGGAAGGGCGGATAGTTTGTGTCTGCAGTGGCACAGATCTAGTGAACATTAGTTTTACCTACATGGTG GCTGAAAATCCAGAAGTAACTAAGCAATGGGTAGAAGGCCTGAGATCAATCATACACAACTTCAGGGCCAACAACGTCAGTCCAATGACA TGCCTCAAGAAACACTGGATGAAATTGGCATTTATGACCAACACAAATGGTAAAATTCCAGTTAGGAGTATTACTAGAACATTTGCATCG GGAAAAACAGAAAAGGTGATCTTTCAAGCACTCAAGGAGTTAGGTCTTCCCAGTGGAAAGAATGATGAAATTGAGCCCACAGCATTTTCT TATGAAAAGTTCTATGAACTGACACAAAAGATTTGTCCTCGGACAGATATAGAAGATCTTTTCAAAAAAATCAATGGAGACAAAACTGAT TATTTAACGGTAGACCAATTAGTGAGCTTTCTAAATGAACATCAACGAGATCCTCGATTGAATGAAATTTTATTTCCATTTTATGATGCC AAAAGGGCAATGCAGATCATTGAGATGTATGAACCTGATGAAGATTTGAAGAAAAAAGGCCTTATATCAAGTGATGGGTTTTGCAGATAT CTGATGTCAGATGAAAACGCCCCAGTCTTCCTAGATCGTTTAGAACTTTACCAAGAAATGGACCATCCTCTGGCTCACTACTTCATCAGT TCTTCCCATAACACTTATCTCACTGGCAGACAGTTCGGCGGGAAGTCTTCGGTAGAAATGTACAGACAGGTTCTCCTGGCTGGTTGCAGA TGTGTTGAACTTGACTGCTGGGATGGAAAAGGTGAAGACCAAGAACCAATAATAACTCATGGAAAAGCAATGTGTACAGATATCCTTTTT AAGGATGTAATTCAAGCCATCAAGGAAACTGCATTTGTCACATCAGAATATCCTGTAATTCTCTCCTTTGAAAATCACTGCAGCAAATAT CAACAGTACAAGATGTCCAAATATTGCGAAGATCTATTTGGGGATCTCCTGTTGAAACAAGCACTTGAATCACATCCACTTGAACCAGGC AGGGCTTTGCCATCCCCCAATGACCTCAAAAGAAAAATACTCATAAAAAACAAGCGGCTGAAACCTGAAGTTGAAAAAAAACAGCTGGAA GCTTTGAGAAGCATGATGGAAGCTGGAGAATCTGCCTCCCCAGCAAACATCTTAGAGGACGATAATGAAGAGGAGATCGAAAGTGCTGAC CAAGAGGAGGAAGCTCACCCCGAATTCAAATTTGGAAATGAACTTTCTGCTGATGACTTGGGTCACAAGGAAGCTGTTGCAAATAGCGTC AAGAAGGCTTCAGATGACCTTGAACATGAAAACAACAAAAAGGGCCTGGTCACTGTAGAAGATGAGCAGGCGTGGATGGCATCTTATAAA TATGTAGGTGCTACCACTAATATCCATCCATATTTGTCCACAATGATCAACTACGCCCAGCCTGTAAAGTTTCAAGGTTTCCATGTGGCA GAAGAACGCAATATTCATTATAACATGTCTTCTTTTAATGAATCAGTCGGTCTTGGCTACTTGAAGACACATGCAATTGAATTTGTCAAT TATAACAAACGGCAAATGAGTCGCATTTACCCCAAGGGAGGCCGAGTCGATTCCAGTAATTACATGCCTCAGATTTTCTGGAACGCTGGC TGCCAGATGGTTTCACTGAACTATCAAACCCCAGATTTAGCGATGCAATTGAATCAGGGAAAATTTGAGTATAATGGATCGTGCGGGTAC CTTCTCAAACCAGATTTCATGAGGCGGCCTGATCGAACATTTGACCCCTTCTCTGAAACTCCTGTTGATGGTGTTATTGCAGCCACTTGC TCAGTGCAGGTTATATCAGGTCAATTCTTATCAGATAAGAAAATTGGCACCTACGTAGAGGTGGATATGTATGGGTTGCCCACTGACACC ATACGTAAGGAATTCCGAACTCGCATGGTTATGAATAATGGACTCAATCCAGTTTACAATGAAGAGTCATTTGTATTTCGGAAGGTGATC CTGCCGGACCTGGCTGTCTTGAGAATAGCTGTGTATGATGATAACAACAAGCTGATTGGCCAGAGGATCCTCCCGCTTGATGGCCTCCAA GCCGGATATCGACACATTTCCCTTCGAAATGAGGGAAATAAACCATTATCACTACCAACAATTTTCTGCAATATTGTTCTTAAAACATAT GTGCCTGATGGATTTGGAGATATCGTGGATGCTTTATCAGATCCAAAGAAATTTCTCTCAATTACAGAAAAGAGAGCAGACCAAATGAGA GCTATGGGCATTGAAACTAGTGACATAGCCGACGTGCCCAGTGACACTTCCAAAAATGACAAGAAAGGAAAGGCCAACACCGCCAAAGCA AATGTGACCCCTCAGAGTAGCTCTGAGCTCAGACCAACCACCACGGCTGCCCTGGCCTCTGGTGTGGAAGCCAAGAAAGGTATTGAACTT ATCCCTCAAGTAAGGATAGAAGACTTAAAGCAGATGAAGGCTTACTTGAAGCATTTAAAGAAACAGCAGAAGGAGCTAAATTCTTTAAAG AAGAAACATGCAAAGATGTTCCAGGTCATCCAGCCAGAGCGTGCGCTGTACATCCAGGCCAACAACTGCGTGGAGGCCAAGGACTGGATC GACATTCTCACCAAAGTGAGCCAGTGCAACCAGAAGCGCCTCACCGTCTACCACCCGTCCGCCTACCTGAGCGGCCACTGGCTGTGCTGT AGGGCGCCATCCGACTCGGCTCCGGGCTGCTCGCCCTGCACTGGCGGCCTCCCAGCCAACATCCAGCTGGACATTGATGGGGACCGTGAG ACGGAGCGTATCTACTCCCTCTTCAACTTGTACATGAGCAAGCTGGAGAAGATGCAGGAGGCCTGTGGGAGCAAATCTGTGTATGACGGC CCGGAGCAGGAGGAGTATTCGACGTTCGTCATTGACGACCCCCAGGAGACCTACAAGACGCTAAAGCAAGTCATCGCTGGGGTTGGGGCT TTGGAGCAGGAGCACGCCCAGTATAAGAGGGACAAGTTCAAGAAGACGAAATATGGAAGCCAGGAGCACCCCATCGGAGACAAGAGCTTC CAGAACTACATCCGGCAGCAGTCCGAGACCTCCACTCATTCCATTTAAAGTCTGCGGGACGCGCCCAGTGGCGCCAGCAAGCTGCCCATG CAAAGCCGCAGCCTTTGGGAGGGAGAAGAGAAGGAAGAGCGCAGAGCCGGCAAAGTGAGATGCACGCCGTCCCGGCCCATAGACAAGTGG CGCTGGGGTTTCCCTCTCCCAGAACCGCTGCCACCACCGCCACGCCCTCCGCAGAAAGCCCACCTGGCCCTGTGGAACGTGTCGTCATTT GATTCTGTGCTTTTTGCTCCTTGTTTGTGGGGATCTGGGGATCAGCTGAAGGATCAGGAAGTGTGGGCTGTGCCCTAGCCACACCACAGC CAGCCTCAGGGAGCCACGGCCCGTCTAGTCGACTGTGACATGCACCTCCGGCCGTGTGTGCGTCAGTCTCGTGCACGTCTGTCTTGCGTG CACGGTGCGTGTGACGCTGGGCTCTGTGGCTCTGTGCCCGGGAGGCCTGCTGGCCCCGCCTCGGCTTTCGGCTTCATCACATTGGGAGGT TCAGAGCATTACTCTCCCACTGTGCCTGCCATCCAGGCAGCCATGGGAGGCGGCCTCCCTGTTCCACTTTCGAGGTTCGTTTGATTCCTG GCTGAGGGGTCAGTTTTATGGCTGGGAGGTGCAGAATTACACAGAAGTCCCAGTCTGAGGATGTCCTTGGTGCTTGGGGGATACGGGTTC TGTCCACAGAGTCCCTTGGAGGGAAAGGTGTGGGCTCCAGCTTCTCCAGGCGTCTGCGGAGCCCACAGTTGAAGCCCACATCGTTTTGCT GTTGAATGGGGTTTAAAATCAGAATTAACATTTGCCACCCCCCGTGGAAGTTTGAAGATTTTAAAAATAGAAATGTACATTTTTCAAGCT GTTTTTCTTTATGTTTTTGAAGGACCATTTTTAATTAGCTCTTTGATACAAAGTAACTCAGAACGTCAAAACCTATACCCACTAAAGGGA AGGCTGCCGGGAAGGCAAATGGAACAGGAATGGAGCCTGTCTCAGGAAGGCCAGCTGCAGGTCCTCCAGAAAATCAAAGAAGGGAAGAAA CTCTGAGTTTGAGGTACAGGGGCTTCGGGGTGCAGACGTCCCTCCAGGGCCCATGGTCAGTATTGCACCTGTGTTATGAACCCCCAGATG CTGTGCAGGGCAGGGGCGGGGGCTGCTGTTTTATTGGGGAGGGGAGCATCCTAAAAATGGGGTCCAGGCAGACCCCTCCAGACCTCACAC TGCCGAGGAGGCCTTTCCCAAAGGGCGTCCTCCCGGGATGCAGACGGCAGGTGTGTGGGAAGCGCCGTTTAAATACACAGCACGACGTAT CCTTGTACCGACTTCTCCCGGTTCTTGTTTGAAAATACTGTAGTTCAGGCTCTTGATCTAGATGGCAGATAGGAACTTTCTTGTCACAAA AATACTGGAGGAAAATGTTGTAAAAATAGACTTTTGGACACACAGCTGTTGGGGCTGCACTGAGCTGCAATTTTTAACATGGATTTATAA >66002_66002_11_PLCB4-RASA3_PLCB4_chr20_9424890_ENST00000414679_RASA3_chr13_114762215_ENST00000334062_length(amino acids)=1154AA_BP=964 MNIIMAKPYEFNWQKEVPSFLQEGAVFDRYEEESFVFEPNCLFKVDEFGFFLTWRSEGKEGQVLECSLINSIRSGAIPKDPKILAALEAV GKSENDLEGRIVCVCSGTDLVNISFTYMVAENPEVTKQWVEGLRSIIHNFRANNVSPMTCLKKHWMKLAFMTNTNGKIPVRSITRTFASG KTEKVIFQALKELGLPSGKNDEIEPTAFSYEKFYELTQKICPRTDIEDLFKKINGDKTDYLTVDQLVSFLNEHQRDPRLNEILFPFYDAK RAMQIIEMYEPDEDLKKKGLISSDGFCRYLMSDENAPVFLDRLELYQEMDHPLAHYFISSSHNTYLTGRQFGGKSSVEMYRQVLLAGCRC VELDCWDGKGEDQEPIITHGKAMCTDILFKDVIQAIKETAFVTSEYPVILSFENHCSKYQQYKMSKYCEDLFGDLLLKQALESHPLEPGR ALPSPNDLKRKILIKNKRLKPEVEKKQLEALRSMMEAGESASPANILEDDNEEEIESADQEEEAHPEFKFGNELSADDLGHKEAVANSVK KASDDLEHENNKKGLVTVEDEQAWMASYKYVGATTNIHPYLSTMINYAQPVKFQGFHVAEERNIHYNMSSFNESVGLGYLKTHAIEFVNY NKRQMSRIYPKGGRVDSSNYMPQIFWNAGCQMVSLNYQTPDLAMQLNQGKFEYNGSCGYLLKPDFMRRPDRTFDPFSETPVDGVIAATCS VQVISGQFLSDKKIGTYVEVDMYGLPTDTIRKEFRTRMVMNNGLNPVYNEESFVFRKVILPDLAVLRIAVYDDNNKLIGQRILPLDGLQA GYRHISLRNEGNKPLSLPTIFCNIVLKTYVPDGFGDIVDALSDPKKFLSITEKRADQMRAMGIETSDIADVPSDTSKNDKKGKANTAKAN VTPQSSSELRPTTTAALASGVEAKKGIELIPQVRIEDLKQMKAYLKHLKKQQKELNSLKKKHAKMFQVIQPERALYIQANNCVEAKDWID ILTKVSQCNQKRLTVYHPSAYLSGHWLCCRAPSDSAPGCSPCTGGLPANIQLDIDGDRETERIYSLFNLYMSKLEKMQEACGSKSVYDGP -------------------------------------------------------------- >66002_66002_12_PLCB4-RASA3_PLCB4_chr20_9424890_ENST00000414679_RASA3_chr13_114762215_ENST00000389544_length(transcript)=3788nt_BP=2895nt GTCTTGAATATAATCATGGCCAAACCTTATGAATTTAACTGGCAGAAGGAAGTTCCCTCCTTTTTGCAAGAAGGAGCAGTTTTTGACAGA TACGAGGAGGAATCCTTTGTGTTTGAACCCAACTGCCTCTTCAAAGTGGATGAGTTTGGCTTCTTTCTGACATGGAGAAGTGAAGGCAAG GAAGGACAGGTGCTAGAATGCTCCCTCATCAACAGTATTCGGTCGGGAGCCATACCAAAGGATCCCAAAATCTTGGCTGCTCTTGAAGCT GTTGGAAAATCAGAAAATGATCTGGAAGGGCGGATAGTTTGTGTCTGCAGTGGCACAGATCTAGTGAACATTAGTTTTACCTACATGGTG GCTGAAAATCCAGAAGTAACTAAGCAATGGGTAGAAGGCCTGAGATCAATCATACACAACTTCAGGGCCAACAACGTCAGTCCAATGACA TGCCTCAAGAAACACTGGATGAAATTGGCATTTATGACCAACACAAATGGTAAAATTCCAGTTAGGAGTATTACTAGAACATTTGCATCG GGAAAAACAGAAAAGGTGATCTTTCAAGCACTCAAGGAGTTAGGTCTTCCCAGTGGAAAGAATGATGAAATTGAGCCCACAGCATTTTCT TATGAAAAGTTCTATGAACTGACACAAAAGATTTGTCCTCGGACAGATATAGAAGATCTTTTCAAAAAAATCAATGGAGACAAAACTGAT TATTTAACGGTAGACCAATTAGTGAGCTTTCTAAATGAACATCAACGAGATCCTCGATTGAATGAAATTTTATTTCCATTTTATGATGCC AAAAGGGCAATGCAGATCATTGAGATGTATGAACCTGATGAAGATTTGAAGAAAAAAGGCCTTATATCAAGTGATGGGTTTTGCAGATAT CTGATGTCAGATGAAAACGCCCCAGTCTTCCTAGATCGTTTAGAACTTTACCAAGAAATGGACCATCCTCTGGCTCACTACTTCATCAGT TCTTCCCATAACACTTATCTCACTGGCAGACAGTTCGGCGGGAAGTCTTCGGTAGAAATGTACAGACAGGTTCTCCTGGCTGGTTGCAGA TGTGTTGAACTTGACTGCTGGGATGGAAAAGGTGAAGACCAAGAACCAATAATAACTCATGGAAAAGCAATGTGTACAGATATCCTTTTT AAGGATGTAATTCAAGCCATCAAGGAAACTGCATTTGTCACATCAGAATATCCTGTAATTCTCTCCTTTGAAAATCACTGCAGCAAATAT CAACAGTACAAGATGTCCAAATATTGCGAAGATCTATTTGGGGATCTCCTGTTGAAACAAGCACTTGAATCACATCCACTTGAACCAGGC AGGGCTTTGCCATCCCCCAATGACCTCAAAAGAAAAATACTCATAAAAAACAAGCGGCTGAAACCTGAAGTTGAAAAAAAACAGCTGGAA GCTTTGAGAAGCATGATGGAAGCTGGAGAATCTGCCTCCCCAGCAAACATCTTAGAGGACGATAATGAAGAGGAGATCGAAAGTGCTGAC CAAGAGGAGGAAGCTCACCCCGAATTCAAATTTGGAAATGAACTTTCTGCTGATGACTTGGGTCACAAGGAAGCTGTTGCAAATAGCGTC AAGAAGGCTTCAGATGACCTTGAACATGAAAACAACAAAAAGGGCCTGGTCACTGTAGAAGATGAGCAGGCGTGGATGGCATCTTATAAA TATGTAGGTGCTACCACTAATATCCATCCATATTTGTCCACAATGATCAACTACGCCCAGCCTGTAAAGTTTCAAGGTTTCCATGTGGCA GAAGAACGCAATATTCATTATAACATGTCTTCTTTTAATGAATCAGTCGGTCTTGGCTACTTGAAGACACATGCAATTGAATTTGTCAAT TATAACAAACGGCAAATGAGTCGCATTTACCCCAAGGGAGGCCGAGTCGATTCCAGTAATTACATGCCTCAGATTTTCTGGAACGCTGGC TGCCAGATGGTTTCACTGAACTATCAAACCCCAGATTTAGCGATGCAATTGAATCAGGGAAAATTTGAGTATAATGGATCGTGCGGGTAC CTTCTCAAACCAGATTTCATGAGGCGGCCTGATCGAACATTTGACCCCTTCTCTGAAACTCCTGTTGATGGTGTTATTGCAGCCACTTGC TCAGTGCAGGTTATATCAGGTCAATTCTTATCAGATAAGAAAATTGGCACCTACGTAGAGGTGGATATGTATGGGTTGCCCACTGACACC ATACGTAAGGAATTCCGAACTCGCATGGTTATGAATAATGGACTCAATCCAGTTTACAATGAAGAGTCATTTGTATTTCGGAAGGTGATC CTGCCGGACCTGGCTGTCTTGAGAATAGCTGTGTATGATGATAACAACAAGCTGATTGGCCAGAGGATCCTCCCGCTTGATGGCCTCCAA GCCGGATATCGACACATTTCCCTTCGAAATGAGGGAAATAAACCATTATCACTACCAACAATTTTCTGCAATATTGTTCTTAAAACATAT GTGCCTGATGGATTTGGAGATATCGTGGATGCTTTATCAGATCCAAAGAAATTTCTCTCAATTACAGAAAAGAGAGCAGACCAAATGAGA GCTATGGGCATTGAAACTAGTGACATAGCCGACGTGCCCAGTGACACTTCCAAAAATGACAAGAAAGGAAAGGCCAACACCGCCAAAGCA AATGTGACCCCTCAGAGTAGCTCTGAGCTCAGACCAACCACCACGGCTGCCCTGGCCTCTGGTGTGGAAGCCAAGAAAGGTATTGAACTT ATCCCTCAAGTAAGGATAGAAGACTTAAAGCAGATGAAGGCTTACTTGAAGCATTTAAAGAAACAGCAGAAGGAGCTAAATTCTTTAAAG AAGAAACATGCAAAGATGTTCCAGGTCATCCAGCCAGAGCGTGCGCTGTACATCCAGGCCAACAACTGCGTGGAGGCCAAGGACTGGATC GACATTCTCACCAAAGTGAGCCAGTGCAACCAGAAGCGCCTCACCGTCTACCACCCGTCCGCCTACCTGAGCGGCCACTGGCTGTGCTGT AGGGCGCCATCCGACTCGGCTCCGGGCTGCTCGCCCTGCACTGGCGGCCTCCCAGCCAACATCCAGCTGGACATTGATGGGGACCGTGAG ACGGAGCGTATCTACTCCCTCTTCAACTTGTACATGAGCAAGCTGGAGAAGATGCAGGAGGCCTGTGGGAGCAAATCTGTGTATGACGGC CCGGAGCAGGAGGAGTATTCGACGTTCGTCATTGACGACCCCCAGGAGACCTACAAGACGCTAAAGCAAGTCATCGCTGGGGTTGGGGCT TTGGAGCAGGAGCACGCCCAGTATAAGAGGGACAAGTTCAAGAAGACGAAATATGGAAGCCAGGAGCACCCCATCGGAGACAAGAGCTTC CAGAACTACATCCGGCAGCAGTCCGAGACCTCCACTCATTCCATTTAAAGTCTGCGGGACGCGCCCAGTGGCGCCAGCAAGCTGCCCATG CAAAGCCGCAGCCTTTGGGAGGGAGAAGAGAAGGAAGAGCGCAGAGCCGGCAAAGTGAGATGCACGCCGTCCCGGCCCATAGACAAGTGG CGCTGGGGTTTCCCTCTCCCAGAACCGCTGCCACCACCGCCACGCCCTCCGCAGAAAGCCCACCTGGCCCTGTGGAACGTGTCGTCATTT GATTCTGTGCTTTTTGCTCCTTGTTTGTGGGGATCTGGGGATCAGCTGAAGGATCAGGAAGTGTGGGCTGTGCCCTAGCCACACCACAGC >66002_66002_12_PLCB4-RASA3_PLCB4_chr20_9424890_ENST00000414679_RASA3_chr13_114762215_ENST00000389544_length(amino acids)=1154AA_BP=964 MNIIMAKPYEFNWQKEVPSFLQEGAVFDRYEEESFVFEPNCLFKVDEFGFFLTWRSEGKEGQVLECSLINSIRSGAIPKDPKILAALEAV GKSENDLEGRIVCVCSGTDLVNISFTYMVAENPEVTKQWVEGLRSIIHNFRANNVSPMTCLKKHWMKLAFMTNTNGKIPVRSITRTFASG KTEKVIFQALKELGLPSGKNDEIEPTAFSYEKFYELTQKICPRTDIEDLFKKINGDKTDYLTVDQLVSFLNEHQRDPRLNEILFPFYDAK RAMQIIEMYEPDEDLKKKGLISSDGFCRYLMSDENAPVFLDRLELYQEMDHPLAHYFISSSHNTYLTGRQFGGKSSVEMYRQVLLAGCRC VELDCWDGKGEDQEPIITHGKAMCTDILFKDVIQAIKETAFVTSEYPVILSFENHCSKYQQYKMSKYCEDLFGDLLLKQALESHPLEPGR ALPSPNDLKRKILIKNKRLKPEVEKKQLEALRSMMEAGESASPANILEDDNEEEIESADQEEEAHPEFKFGNELSADDLGHKEAVANSVK KASDDLEHENNKKGLVTVEDEQAWMASYKYVGATTNIHPYLSTMINYAQPVKFQGFHVAEERNIHYNMSSFNESVGLGYLKTHAIEFVNY NKRQMSRIYPKGGRVDSSNYMPQIFWNAGCQMVSLNYQTPDLAMQLNQGKFEYNGSCGYLLKPDFMRRPDRTFDPFSETPVDGVIAATCS VQVISGQFLSDKKIGTYVEVDMYGLPTDTIRKEFRTRMVMNNGLNPVYNEESFVFRKVILPDLAVLRIAVYDDNNKLIGQRILPLDGLQA GYRHISLRNEGNKPLSLPTIFCNIVLKTYVPDGFGDIVDALSDPKKFLSITEKRADQMRAMGIETSDIADVPSDTSKNDKKGKANTAKAN VTPQSSSELRPTTTAALASGVEAKKGIELIPQVRIEDLKQMKAYLKHLKKQQKELNSLKKKHAKMFQVIQPERALYIQANNCVEAKDWID ILTKVSQCNQKRLTVYHPSAYLSGHWLCCRAPSDSAPGCSPCTGGLPANIQLDIDGDRETERIYSLFNLYMSKLEKMQEACGSKSVYDGP -------------------------------------------------------------- |
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Fusion Gene PPI Analysis for PLCB4-RASA3 |
| Go to ChiPPI (Chimeric Protein-Protein interactions) to see the chimeric PPI interaction in |
| Protein-protein interactors with each fusion partner protein in wild-type (BIOGRID-3.4.160) |
| Hgene | Hgene's interactors | Tgene | Tgene's interactors |
| - Retained PPIs in in-frame fusion. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Still interaction with |
| - Lost PPIs in in-frame fusion. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Interaction lost with |
| - Retained PPIs, but lost function due to frame-shift fusion. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Interaction lost with |
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Related Drugs for PLCB4-RASA3 |
| Drugs targeting genes involved in this fusion gene. (DrugBank Version 5.1.8 2021-05-08) |
| Partner | Gene | UniProtAcc | DrugBank ID | Drug name | Drug activity | Drug type | Drug status |
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Related Diseases for PLCB4-RASA3 |
| Diseases associated with fusion partners. (DisGeNet 4.0) |
| Partner | Gene | Disease ID | Disease name | # pubmeds | Source |
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