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Center for Computational Systems Medicine
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Fusion Gene Summary

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Fusion Gene ORF analysis

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Fusion Genomic Features

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Fusion Protein Features

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Fusion Gene Sequence

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Fusion Gene PPI analysis

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Related Drugs

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Related Diseases

Fusion gene:PLIN1-ACSL6 (FusionGDB2 ID:66353)

Fusion Gene Summary for PLIN1-ACSL6

check button Fusion gene summary
Fusion gene informationFusion gene name: PLIN1-ACSL6
Fusion gene ID: 66353
HgeneTgene
Gene symbol

PLIN1

ACSL6

Gene ID

5346

23305

Gene nameperilipin 1acyl-CoA synthetase long chain family member 6
SynonymsFPLD4|PERI|PLINACS2|FACL6|LACS 6|LACS2|LACS5
Cytomap

15q26.1

5q31.1

Type of geneprotein-codingprotein-coding
Descriptionperilipin-1lipid droplet-associated proteinlong-chain-fatty-acid--CoA ligase 6arachidonate--CoA ligasefatty-acid-Coenzyme A ligase, long-chain 6long fatty acyl-CoA synthetase 2
Modification date2020031520200313
UniProtAcc.

Q9UKU0

Ensembl transtripts involved in fusion geneENST00000300055, ENST00000430628, 
ENST00000357096, ENST00000379240, 
ENST00000431707, ENST00000477640, 
ENST00000296869, ENST00000379244, 
ENST00000379246, ENST00000379249, 
ENST00000379255, ENST00000379264, 
ENST00000379272, ENST00000543479, 
ENST00000544770, 
Fusion gene scores* DoF score2 X 2 X 2=86 X 8 X 8=384
# samples 210
** MAII scorelog2(2/8*10)=1.32192809488736log2(10/384*10)=-1.94110631094643
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0
Context

PubMed: PLIN1 [Title/Abstract] AND ACSL6 [Title/Abstract] AND fusion [Title/Abstract]

Most frequent breakpointPLIN1(90212731)-ACSL6(131321151), # samples:3
Anticipated loss of major functional domain due to fusion event.PLIN1-ACSL6 seems lost the major protein functional domain in Hgene partner, which is a cell metabolism gene due to the frame-shifted ORF.
PLIN1-ACSL6 seems lost the major protein functional domain in Hgene partner, which is a essential gene due to the frame-shifted ORF.
PLIN1-ACSL6 seems lost the major protein functional domain in Tgene partner, which is a cell metabolism gene due to the frame-shifted ORF.
PLIN1-ACSL6 seems lost the major protein functional domain in Tgene partner, which is a CGC due to the frame-shifted ORF.
* DoF score (Degree of Frequency) = # partners X # break points X # cancer types
** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10)

check button Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez
PartnerGeneGO IDGO termPubMed ID
TgeneACSL6

GO:0001676

long-chain fatty acid metabolic process

24269233


check buttonFusion gene breakpoints across PLIN1 (5'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.
all structure

check buttonFusion gene breakpoints across ACSL6 (3'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.
all structure

check button Fusion gene information from two resources (ChiTars 5.0 and ChimerDB 4.0)
* All genome coordinats were lifted-over on hg19.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
SourceDiseaseSampleHgeneHchrHbpHstrandTgeneTchrTbpTstrand
ChimerDB4BRCATCGA-E9-A1RC-01APLIN1chr15

90212731

-ACSL6chr5

131321151

-


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Fusion Gene ORF analysis for PLIN1-ACSL6

check button Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
ORFHenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrand
5CDS-intronENST00000300055ENST00000357096PLIN1chr15

90212731

-ACSL6chr5

131321151

-
5CDS-intronENST00000300055ENST00000379240PLIN1chr15

90212731

-ACSL6chr5

131321151

-
5CDS-intronENST00000300055ENST00000431707PLIN1chr15

90212731

-ACSL6chr5

131321151

-
5CDS-intronENST00000300055ENST00000477640PLIN1chr15

90212731

-ACSL6chr5

131321151

-
5CDS-intronENST00000430628ENST00000357096PLIN1chr15

90212731

-ACSL6chr5

131321151

-
5CDS-intronENST00000430628ENST00000379240PLIN1chr15

90212731

-ACSL6chr5

131321151

-
5CDS-intronENST00000430628ENST00000431707PLIN1chr15

90212731

-ACSL6chr5

131321151

-
5CDS-intronENST00000430628ENST00000477640PLIN1chr15

90212731

-ACSL6chr5

131321151

-
Frame-shiftENST00000300055ENST00000296869PLIN1chr15

90212731

-ACSL6chr5

131321151

-
Frame-shiftENST00000300055ENST00000379244PLIN1chr15

90212731

-ACSL6chr5

131321151

-
Frame-shiftENST00000300055ENST00000379246PLIN1chr15

90212731

-ACSL6chr5

131321151

-
Frame-shiftENST00000300055ENST00000379249PLIN1chr15

90212731

-ACSL6chr5

131321151

-
Frame-shiftENST00000300055ENST00000379255PLIN1chr15

90212731

-ACSL6chr5

131321151

-
Frame-shiftENST00000300055ENST00000379264PLIN1chr15

90212731

-ACSL6chr5

131321151

-
Frame-shiftENST00000300055ENST00000379272PLIN1chr15

90212731

-ACSL6chr5

131321151

-
Frame-shiftENST00000300055ENST00000543479PLIN1chr15

90212731

-ACSL6chr5

131321151

-
Frame-shiftENST00000300055ENST00000544770PLIN1chr15

90212731

-ACSL6chr5

131321151

-
In-frameENST00000430628ENST00000296869PLIN1chr15

90212731

-ACSL6chr5

131321151

-
In-frameENST00000430628ENST00000379244PLIN1chr15

90212731

-ACSL6chr5

131321151

-
In-frameENST00000430628ENST00000379246PLIN1chr15

90212731

-ACSL6chr5

131321151

-
In-frameENST00000430628ENST00000379249PLIN1chr15

90212731

-ACSL6chr5

131321151

-
In-frameENST00000430628ENST00000379255PLIN1chr15

90212731

-ACSL6chr5

131321151

-
In-frameENST00000430628ENST00000379264PLIN1chr15

90212731

-ACSL6chr5

131321151

-
In-frameENST00000430628ENST00000379272PLIN1chr15

90212731

-ACSL6chr5

131321151

-
In-frameENST00000430628ENST00000543479PLIN1chr15

90212731

-ACSL6chr5

131321151

-
In-frameENST00000430628ENST00000544770PLIN1chr15

90212731

-ACSL6chr5

131321151

-

check buttonORFfinder result based on the fusion transcript sequence of in-frame fusion genes.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandSeq length
(transcript)		BP loci
(transcript)		Predicted start
(transcript)		Predicted stop
(transcript)		Seq length
(amino acids)
ENST00000430628PLIN1chr1590212731-ENST00000379249ACSL6chr5131321151-21068911202105661
ENST00000430628PLIN1chr1590212731-ENST00000379264ACSL6chr5131321151-64578911202195691
ENST00000430628PLIN1chr1590212731-ENST00000379272ACSL6chr5131321151-48268911202195691
ENST00000430628PLIN1chr1590212731-ENST00000379255ACSL6chr5131321151-24128911202075651
ENST00000430628PLIN1chr1590212731-ENST00000296869ACSL6chr5131321151-25288911202195691
ENST00000430628PLIN1chr1590212731-ENST00000379246ACSL6chr5131321151-25258911202195691
ENST00000430628PLIN1chr1590212731-ENST00000379244ACSL6chr5131321151-25238911202195691
ENST00000430628PLIN1chr1590212731-ENST00000544770ACSL6chr5131321151-25188911202195691
ENST00000430628PLIN1chr1590212731-ENST00000543479ACSL6chr5131321151-21968911202195691

check buttonDeepORF prediction of the coding potential based on the fusion transcript sequence of in-frame fusion genes. DeepORF is a coding potential classifier based on convolutional neural network by comparing the real Ribo-seq data. If the no-coding score < 0.5 and coding score > 0.5, then the in-frame fusion transcript is predicted as being likely translated.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandNo-coding scoreCoding score
ENST00000430628ENST00000379249PLIN1chr1590212731-ACSL6chr5131321151-0.0079460490.992054
ENST00000430628ENST00000379264PLIN1chr1590212731-ACSL6chr5131321151-0.000499990.99950004
ENST00000430628ENST00000379272PLIN1chr1590212731-ACSL6chr5131321151-0.000918780.99908125
ENST00000430628ENST00000379255PLIN1chr1590212731-ACSL6chr5131321151-0.0035654860.99643457
ENST00000430628ENST00000296869PLIN1chr1590212731-ACSL6chr5131321151-0.0038715570.99612844
ENST00000430628ENST00000379246PLIN1chr1590212731-ACSL6chr5131321151-0.0035092650.99649066
ENST00000430628ENST00000379244PLIN1chr1590212731-ACSL6chr5131321151-0.0039296660.9960704
ENST00000430628ENST00000544770PLIN1chr1590212731-ACSL6chr5131321151-0.0036028430.9963972
ENST00000430628ENST00000543479PLIN1chr1590212731-ACSL6chr5131321151-0.0078318580.9921681

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Fusion Genomic Features for PLIN1-ACSL6


check buttonFusionAI prediction of the potential fusion gene breakpoint based on the pre-mature RNA sequence context (+/- 5kb of individual partner genes, total 20kb length sequence). FusionAI is a fusion gene breakpoint classifier based on convolutional neural network by comparing the fusion positive and negative sequence context of ~ 20K fusion gene data. From here, we can have the relative potentency of the 20K genomic sequence how individual sequnce will be likely used as the gene fusion breakpoints.
HgeneHchrHbpHstrandTgeneTchrTbpTstrand1-pp (fusion gene breakpoint)

check buttonDistribution of 44 human genomic features loci across 20kb length fusion breakpoint regions. We integrated a total of 44 different types of human genomic feature loci information across five big categories including virus integration sites, repeats, structural variants, chromatin states, and gene expression regulation. More details are in help page.
genomic feature

check buttonDistribution of 44 human genomic features loci across 20kb length fusion breakpoint regions that are ovelapped with the top 1% feature importance score regions. More details are in help page.

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Fusion Protein Features for PLIN1-ACSL6


check button Four levels of functional features of fusion genes
Go to FGviewer search page for the most frequent breakpoint (https://ccsmweb.uth.edu/FGviewer/chr15:90212731/chr5:131321151)
- FGviewer provides the online visualization of the retention search of the protein functional features across DNA, RNA, protein, and pathological levels.
- How to search
1. Put your fusion gene symbol.
2. Press the tab key until there will be shown the breakpoint information filled.
4. Go down and press 'Search' tab twice.
4. Go down to have the hyperlink of the search result.
5. Click the hyperlink.
6. See the FGviewer result for your fusion gene.
FGviewer

check buttonMain function of each fusion partner protein. (from UniProt)
HgeneTgene
.ACSL6

Q9UKU0

FUNCTION: Transcriptional activator which is required for calcium-dependent dendritic growth and branching in cortical neurons. Recruits CREB-binding protein (CREBBP) to nuclear bodies. Component of the CREST-BRG1 complex, a multiprotein complex that regulates promoter activation by orchestrating a calcium-dependent release of a repressor complex and a recruitment of an activator complex. In resting neurons, transcription of the c-FOS promoter is inhibited by BRG1-dependent recruitment of a phospho-RB1-HDAC1 repressor complex. Upon calcium influx, RB1 is dephosphorylated by calcineurin, which leads to release of the repressor complex. At the same time, there is increased recruitment of CREBBP to the promoter by a CREST-dependent mechanism, which leads to transcriptional activation. The CREST-BRG1 complex also binds to the NR2B promoter, and activity-dependent induction of NR2B expression involves a release of HDAC1 and recruitment of CREBBP (By similarity). {ECO:0000250}.FUNCTION: Catalyzes the conversion of long-chain fatty acids to their active form acyl-CoA for both synthesis of cellular lipids, and degradation via beta-oxidation (PubMed:22633490, PubMed:24269233). Plays an important role in fatty acid metabolism in brain and the acyl-CoAs produced may be utilized exclusively for the synthesis of the brain lipid. {ECO:0000269|PubMed:22633490, ECO:0000269|PubMed:24269233}.

check buttonRetention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at

download page


* Minus value of BPloci means that the break pointn is located before the CDS.
- In-frame and retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note

- In-frame and not-retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
HgenePLIN1chr15:90212731chr5:131321151ENST00000300055-69307_316257523.0Compositional biasNote=Poly-Glu
HgenePLIN1chr15:90212731chr5:131321151ENST00000430628-69307_316257523.0Compositional biasNote=Poly-Glu
TgeneACSL6chr15:90212731chr5:131321151ENST0000029686972146_697288723.0Topological domainCytoplasmic
TgeneACSL6chr15:90212731chr5:131321151ENST0000035709661946_697228623.0Topological domainCytoplasmic
TgeneACSL6chr15:90212731chr5:131321151ENST0000037924072146_697263698.0Topological domainCytoplasmic
TgeneACSL6chr15:90212731chr5:131321151ENST0000037924472146_697263698.0Topological domainCytoplasmic
TgeneACSL6chr15:90212731chr5:131321151ENST0000037924672146_697274709.0Topological domainCytoplasmic
TgeneACSL6chr15:90212731chr5:131321151ENST0000037924972146_697263668.0Topological domainCytoplasmic
TgeneACSL6chr15:90212731chr5:131321151ENST0000037925572046_697228623.0Topological domainCytoplasmic
TgeneACSL6chr15:90212731chr5:131321151ENST0000037926472146_697288723.0Topological domainCytoplasmic
TgeneACSL6chr15:90212731chr5:131321151ENST0000037927282246_697278713.0Topological domainCytoplasmic
TgeneACSL6chr15:90212731chr5:131321151ENST0000054347972146_697263698.0Topological domainCytoplasmic
TgeneACSL6chr15:90212731chr5:131321151ENST0000029686972125_45288723.0TransmembraneHelical%3B Signal-anchor for type III membrane protein
TgeneACSL6chr15:90212731chr5:131321151ENST0000035709661925_45228623.0TransmembraneHelical%3B Signal-anchor for type III membrane protein
TgeneACSL6chr15:90212731chr5:131321151ENST0000037924072125_45263698.0TransmembraneHelical%3B Signal-anchor for type III membrane protein
TgeneACSL6chr15:90212731chr5:131321151ENST0000037924472125_45263698.0TransmembraneHelical%3B Signal-anchor for type III membrane protein
TgeneACSL6chr15:90212731chr5:131321151ENST0000037924672125_45274709.0TransmembraneHelical%3B Signal-anchor for type III membrane protein
TgeneACSL6chr15:90212731chr5:131321151ENST0000037924972125_45263668.0TransmembraneHelical%3B Signal-anchor for type III membrane protein
TgeneACSL6chr15:90212731chr5:131321151ENST0000037925572025_45228623.0TransmembraneHelical%3B Signal-anchor for type III membrane protein
TgeneACSL6chr15:90212731chr5:131321151ENST0000037926472125_45288723.0TransmembraneHelical%3B Signal-anchor for type III membrane protein
TgeneACSL6chr15:90212731chr5:131321151ENST0000037927282225_45278713.0TransmembraneHelical%3B Signal-anchor for type III membrane protein
TgeneACSL6chr15:90212731chr5:131321151ENST0000054347972125_45263698.0TransmembraneHelical%3B Signal-anchor for type III membrane protein


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Fusion Gene Sequence for PLIN1-ACSL6


check button For in-frame fusion transcripts, we provide the fusion transcript sequences and fusion amino acid sequences. To have fusion amino acid sequence, we ran ORFfinder and chose the longest ORF among the all predicted ones.
>66353_66353_1_PLIN1-ACSL6_PLIN1_chr15_90212731_ENST00000430628_ACSL6_chr5_131321151_ENST00000296869_length(transcript)=2528nt_BP=891nt
TGGAAGCAGCATTGCCCAAGCCTCCCAGGAGTGACAGGAATTGTTTCTGCCTGAGGAGACACTCTGCAGCCTGGGCTCTGTGAGACTGAG
GTGGCGGTCAGCCGGACTTGAGGAGCGAGGATGGCAGTCAACAAAGGCCTCACCTTGCTGGATGGAGACCTCCCTGAGCAGGAGAATGTG
CTGCAGCGGGTCCTGCAGCTGCCGGTGGTGAGTGGCACCTGCGAATGCTTCCAGAAGACCTACACCAGCACTAAGGAAGCCCACCCCCTG
GTGGCCTCTGTGTGCAATGCCTATGAGAAGGGCGTGCAGAGCGCCAGTAGCTTGGCTGCCTGGAGCATGGAGCCGGTGGTCCGCAGGCTG
TCCACCCAGTTCACAGCTGCCAATGAGCTGGCCTGCCGAGGCTTGGACCACCTGGAGGAAAAGATCCCCGCCCTCCAGTACCCCCCTGAA
AAGATTGCTTCTGAGCTGAAGGACACCATCTCCACCCGCCTCCGCAGTGCCAGAAACAGCATCAGCGTTCCCATCGCGAGCACTTCAGAC
AAGGTCCTGGGGGCCGCTTTGGCCGGGTGCGAGCTTGCCTGGGGGGTGGCCAGAGACACTGCGGAATTTGCTGCCAACACTCGAGCTGGC
CGACTGGCTTCTGGAGGGGCCGACTTGGCCTTGGGCAGCATTGAGAAGGTGGTGGAGTACCTCCTCCCTCCAGACAAGGAAGAGTCAGCC
CCTGCTCCTGGACACCAGCAAGCCCAGAAGTCTCCCAAGGCCAAGCCAAGCCTCTTGAGCAGGGTTGGGGCTCTGACCAACACCCTCTCT
CGATACACCGTGCAGACCATGGCCCGGGCCCTGGAGCAGGGCCACACCGTGGCCATGTGGATCCCAGGCGTGGTGCCCCTGCCCCCGCAG
CCTGATGACCTCTCCATTGTGTGTTTCACAAGCGGCACGACAGGGAACCCAAAAGGTGCGATGCTCACCCATGGGAACGTGGTGGCTGAT
TTCTCAGGCTTTCTGAAAGTGACAGAGAGTCAGTGGGCTCCCACTTGTGCGGATGTGCACATTTCCTATTTGCCTTTAGCACACATGTTT
GAGCGAATGGTGCAGTCTGTCGTCTATTGCCACGGAGGGCGTGTTGGCTTCTTCCAGGGAGATATCCGCCTTCTCTCAGATGACATGAAG
GCTCTATGCCCCACCATCTTCCCTGTGGTCCCACGACTGCTGAACCGGATGTACGACAAGATCTTCAGCCAGGCAAACACACCATTAAAG
CGCTGGCTCCTGGAGTTTGCAGCAAAGCGTAAGCAAGCCGAGGTCCGGAGTGGAATCATCAGGAATGATAGTATCTGGGATGAACTCTTC
TTTAATAAGATTCAGGCCAGTCTTGGTGGGTGTGTGCGGATGATTGTTACTGGAGCAGCCCCAGCATCACCAACAGTTCTGGGATTTCTC
CGGGCAGCTCTAGGGTGCCAGGTTTATGAAGGTTATGGCCAAACTGAGTGCACAGCTGGATGTACCTTCACCACTCCTGGCGACTGGACC
TCAGGGCACGTAGGGGCGCCACTTCCCTGCAATCATATCAAGCTCGTTGATGTTGAGGAACTGAACTACTGGGCCTGCAAAGGAGAGGGA
GAGATATGTGTGAGAGGACCAAATGTGTTCAAAGGCTACTTGAAAGATCCAGACAGGACGAAGGAGGCCCTGGACAGCGATGGCTGGCTT
CACACTGGAGACATCGGAAAATGGCTGCCGGCAGGAACTCTTAAAATTATTGATCGGAAAAAGCATATATTTAAACTTGCTCAGGGAGAA
TATGTTGCACCCGAGAAGATTGAGAACATCTACATCCGGAGCCAACCTGTGGCGCAAATCTATGTCCATGGGGACAGCTTAAAGGCCTTT
TTGGTAGGCATTGTTGTGCCTGACCCTGAAGTTATGCCCTCCTGGGCCCAGAAGAGAGGAATTGAAGGAACATATGCAGATCTCTGCACA
AATAAGGATCTGAAGAAAGCCATTTTGGAAGATATGGTGAGGTTAGGAAAAGAAAGTGGACTCCATTCTTTTGAGCAGGTTAAAGCCATT
CACATCCATTCTGACATGTTCTCAGTTCAAAATGGCTTGCTGACACCAACACTAAAAGCTAAGAGACCTGAGCTGAGAGAGTACTTCAAA
AAACAAATAGAAGAGCTTTACTCAATCTCCATGTGAAGTTCAAGGAAAGTTCTTCTCAGTGTAATGAACTGTCTAGCAATATTATAGTTA
TTCTTGAAAGTAATGAGTCAAAATGACACAGCTGAAAATGAATAAGCATCTGATTTTATGACTGAGCCTTTTCCTGTCCCAAGAGGTCTT
TAACAATATTTTCTCTATCATCAATGAGTATATTTTATTTTTATTATAAAAATGATATTGTGGTGGACTGCTAAAAATATCACAAATGGC
AATGTAAAAATCAAGACATTTTCTCAAGAACTGTGTACCACTAAAAGTAATATATTGTCAATGTTCACAGAACTATTAAACATAAAGGAA

>66353_66353_1_PLIN1-ACSL6_PLIN1_chr15_90212731_ENST00000430628_ACSL6_chr5_131321151_ENST00000296869_length(amino acids)=691AA_BP=257
MAVNKGLTLLDGDLPEQENVLQRVLQLPVVSGTCECFQKTYTSTKEAHPLVASVCNAYEKGVQSASSLAAWSMEPVVRRLSTQFTAANEL
ACRGLDHLEEKIPALQYPPEKIASELKDTISTRLRSARNSISVPIASTSDKVLGAALAGCELAWGVARDTAEFAANTRAGRLASGGADLA
LGSIEKVVEYLLPPDKEESAPAPGHQQAQKSPKAKPSLLSRVGALTNTLSRYTVQTMARALEQGHTVAMWIPGVVPLPPQPDDLSIVCFT
SGTTGNPKGAMLTHGNVVADFSGFLKVTESQWAPTCADVHISYLPLAHMFERMVQSVVYCHGGRVGFFQGDIRLLSDDMKALCPTIFPVV
PRLLNRMYDKIFSQANTPLKRWLLEFAAKRKQAEVRSGIIRNDSIWDELFFNKIQASLGGCVRMIVTGAAPASPTVLGFLRAALGCQVYE
GYGQTECTAGCTFTTPGDWTSGHVGAPLPCNHIKLVDVEELNYWACKGEGEICVRGPNVFKGYLKDPDRTKEALDSDGWLHTGDIGKWLP
AGTLKIIDRKKHIFKLAQGEYVAPEKIENIYIRSQPVAQIYVHGDSLKAFLVGIVVPDPEVMPSWAQKRGIEGTYADLCTNKDLKKAILE

--------------------------------------------------------------
>66353_66353_2_PLIN1-ACSL6_PLIN1_chr15_90212731_ENST00000430628_ACSL6_chr5_131321151_ENST00000379244_length(transcript)=2523nt_BP=891nt
TGGAAGCAGCATTGCCCAAGCCTCCCAGGAGTGACAGGAATTGTTTCTGCCTGAGGAGACACTCTGCAGCCTGGGCTCTGTGAGACTGAG
GTGGCGGTCAGCCGGACTTGAGGAGCGAGGATGGCAGTCAACAAAGGCCTCACCTTGCTGGATGGAGACCTCCCTGAGCAGGAGAATGTG
CTGCAGCGGGTCCTGCAGCTGCCGGTGGTGAGTGGCACCTGCGAATGCTTCCAGAAGACCTACACCAGCACTAAGGAAGCCCACCCCCTG
GTGGCCTCTGTGTGCAATGCCTATGAGAAGGGCGTGCAGAGCGCCAGTAGCTTGGCTGCCTGGAGCATGGAGCCGGTGGTCCGCAGGCTG
TCCACCCAGTTCACAGCTGCCAATGAGCTGGCCTGCCGAGGCTTGGACCACCTGGAGGAAAAGATCCCCGCCCTCCAGTACCCCCCTGAA
AAGATTGCTTCTGAGCTGAAGGACACCATCTCCACCCGCCTCCGCAGTGCCAGAAACAGCATCAGCGTTCCCATCGCGAGCACTTCAGAC
AAGGTCCTGGGGGCCGCTTTGGCCGGGTGCGAGCTTGCCTGGGGGGTGGCCAGAGACACTGCGGAATTTGCTGCCAACACTCGAGCTGGC
CGACTGGCTTCTGGAGGGGCCGACTTGGCCTTGGGCAGCATTGAGAAGGTGGTGGAGTACCTCCTCCCTCCAGACAAGGAAGAGTCAGCC
CCTGCTCCTGGACACCAGCAAGCCCAGAAGTCTCCCAAGGCCAAGCCAAGCCTCTTGAGCAGGGTTGGGGCTCTGACCAACACCCTCTCT
CGATACACCGTGCAGACCATGGCCCGGGCCCTGGAGCAGGGCCACACCGTGGCCATGTGGATCCCAGGCGTGGTGCCCCTGCCCCCGCAG
CCTGATGACCTCTCCATTGTGTGTTTCACAAGCGGCACGACAGGGAACCCAAAAGGTGCGATGCTCACCCATGGGAACGTGGTGGCTGAT
TTCTCAGGCTTTCTGAAAGTGACAGAGAGTCAGTGGGCTCCCACTTGTGCGGATGTGCACATTTCCTATTTGCCTTTAGCACACATGTTT
GAGCGAATGGTGCAGTCTGTCGTCTATTGCCACGGAGGGCGTGTTGGCTTCTTCCAGGGAGATATCCGCCTTCTCTCAGATGACATGAAG
GCTCTATGCCCCACCATCTTCCCTGTGGTCCCACGACTGCTGAACCGGATGTACGACAAGATCTTCAGCCAGGCAAACACACCATTAAAG
CGCTGGCTCCTGGAGTTTGCAGCAAAGCGTAAGCAAGCCGAGGTCCGGAGTGGAATCATCAGGAATGATAGTATCTGGGATGAACTCTTC
TTTAATAAGATTCAGGCCAGTCTTGGTGGGTGTGTGCGGATGATTGTTACTGGAGCAGCCCCAGCATCACCAACAGTTCTGGGATTTCTC
CGGGCAGCTCTAGGGTGCCAGGTTTATGAAGGTTATGGCCAAACTGAGTGCACAGCTGGATGTACCTTCACCACTCCTGGCGACTGGACC
TCAGGGCACGTAGGGGCGCCACTTCCCTGCAATCATATCAAGCTCGTTGATGTTGAGGAACTGAACTACTGGGCCTGCAAAGGAGAGGGA
GAGATATGTGTGAGAGGACCAAATGTGTTCAAAGGCTACTTGAAAGATCCAGACAGGACGAAGGAGGCCCTGGACAGCGATGGCTGGCTT
CACACTGGAGACATCGGAAAATGGCTGCCGGCAGGAACTCTTAAAATTATTGATCGGAAAAAGCATATATTTAAACTTGCTCAGGGAGAA
TATGTTGCACCCGAGAAGATTGAGAACATCTACATCCGGAGCCAACCTGTGGCGCAAATCTATGTCCATGGGGACAGCTTAAAGGCCTTT
TTGGTAGGCATTGTTGTGCCTGACCCTGAAGTTATGCCCTCCTGGGCCCAGAAGAGAGGAATTGAAGGAACATATGCAGATCTCTGCACA
AATAAGGATCTGAAGAAAGCCATTTTGGAAGATATGGTGAGGTTAGGAAAAGAAAGTGGACTCCATTCTTTTGAGCAGGTTAAAGCCATT
CACATCCATTCTGACATGTTCTCAGTTCAAAATGGCTTGCTGACACCAACACTAAAAGCTAAGAGACCTGAGCTGAGAGAGTACTTCAAA
AAACAAATAGAAGAGCTTTACTCAATCTCCATGTGAAGTTCAAGGAAAGTTCTTCTCAGTGTAATGAACTGTCTAGCAATATTATAGTTA
TTCTTGAAAGTAATGAGTCAAAATGACACAGCTGAAAATGAATAAGCATCTGATTTTATGACTGAGCCTTTTCCTGTCCCAAGAGGTCTT
TAACAATATTTTCTCTATCATCAATGAGTATATTTTATTTTTATTATAAAAATGATATTGTGGTGGACTGCTAAAAATATCACAAATGGC
AATGTAAAAATCAAGACATTTTCTCAAGAACTGTGTACCACTAAAAGTAATATATTGTCAATGTTCACAGAACTATTAAACATAAAGGAA

>66353_66353_2_PLIN1-ACSL6_PLIN1_chr15_90212731_ENST00000430628_ACSL6_chr5_131321151_ENST00000379244_length(amino acids)=691AA_BP=257
MAVNKGLTLLDGDLPEQENVLQRVLQLPVVSGTCECFQKTYTSTKEAHPLVASVCNAYEKGVQSASSLAAWSMEPVVRRLSTQFTAANEL
ACRGLDHLEEKIPALQYPPEKIASELKDTISTRLRSARNSISVPIASTSDKVLGAALAGCELAWGVARDTAEFAANTRAGRLASGGADLA
LGSIEKVVEYLLPPDKEESAPAPGHQQAQKSPKAKPSLLSRVGALTNTLSRYTVQTMARALEQGHTVAMWIPGVVPLPPQPDDLSIVCFT
SGTTGNPKGAMLTHGNVVADFSGFLKVTESQWAPTCADVHISYLPLAHMFERMVQSVVYCHGGRVGFFQGDIRLLSDDMKALCPTIFPVV
PRLLNRMYDKIFSQANTPLKRWLLEFAAKRKQAEVRSGIIRNDSIWDELFFNKIQASLGGCVRMIVTGAAPASPTVLGFLRAALGCQVYE
GYGQTECTAGCTFTTPGDWTSGHVGAPLPCNHIKLVDVEELNYWACKGEGEICVRGPNVFKGYLKDPDRTKEALDSDGWLHTGDIGKWLP
AGTLKIIDRKKHIFKLAQGEYVAPEKIENIYIRSQPVAQIYVHGDSLKAFLVGIVVPDPEVMPSWAQKRGIEGTYADLCTNKDLKKAILE

--------------------------------------------------------------
>66353_66353_3_PLIN1-ACSL6_PLIN1_chr15_90212731_ENST00000430628_ACSL6_chr5_131321151_ENST00000379246_length(transcript)=2525nt_BP=891nt
TGGAAGCAGCATTGCCCAAGCCTCCCAGGAGTGACAGGAATTGTTTCTGCCTGAGGAGACACTCTGCAGCCTGGGCTCTGTGAGACTGAG
GTGGCGGTCAGCCGGACTTGAGGAGCGAGGATGGCAGTCAACAAAGGCCTCACCTTGCTGGATGGAGACCTCCCTGAGCAGGAGAATGTG
CTGCAGCGGGTCCTGCAGCTGCCGGTGGTGAGTGGCACCTGCGAATGCTTCCAGAAGACCTACACCAGCACTAAGGAAGCCCACCCCCTG
GTGGCCTCTGTGTGCAATGCCTATGAGAAGGGCGTGCAGAGCGCCAGTAGCTTGGCTGCCTGGAGCATGGAGCCGGTGGTCCGCAGGCTG
TCCACCCAGTTCACAGCTGCCAATGAGCTGGCCTGCCGAGGCTTGGACCACCTGGAGGAAAAGATCCCCGCCCTCCAGTACCCCCCTGAA
AAGATTGCTTCTGAGCTGAAGGACACCATCTCCACCCGCCTCCGCAGTGCCAGAAACAGCATCAGCGTTCCCATCGCGAGCACTTCAGAC
AAGGTCCTGGGGGCCGCTTTGGCCGGGTGCGAGCTTGCCTGGGGGGTGGCCAGAGACACTGCGGAATTTGCTGCCAACACTCGAGCTGGC
CGACTGGCTTCTGGAGGGGCCGACTTGGCCTTGGGCAGCATTGAGAAGGTGGTGGAGTACCTCCTCCCTCCAGACAAGGAAGAGTCAGCC
CCTGCTCCTGGACACCAGCAAGCCCAGAAGTCTCCCAAGGCCAAGCCAAGCCTCTTGAGCAGGGTTGGGGCTCTGACCAACACCCTCTCT
CGATACACCGTGCAGACCATGGCCCGGGCCCTGGAGCAGGGCCACACCGTGGCCATGTGGATCCCAGGCGTGGTGCCCCTGCCCCCGCAG
CCTGATGACCTCTCCATTGTGTGTTTCACAAGCGGCACGACAGGGAACCCAAAAGGTGCGATGCTCACCCATGGGAACGTGGTGGCTGAT
TTCTCAGGCTTTCTGAAAGTGACAGAGAAAGTGATCTTTCCGAGACAGGACGATGTGCTCATCTCCTTCCTGCCTCTGGCTCACATGTTT
GAGAGAGTAATCCAGTCTGTCGTCTATTGCCACGGAGGGCGTGTTGGCTTCTTCCAGGGAGATATCCGCCTTCTCTCAGATGACATGAAG
GCTCTATGCCCCACCATCTTCCCTGTGGTCCCACGACTGCTGAACCGGATGTACGACAAGATCTTCAGCCAGGCAAACACACCATTAAAG
CGCTGGCTCCTGGAGTTTGCAGCAAAGCGTAAGCAAGCCGAGGTCCGGAGTGGAATCATCAGGAATGATAGTATCTGGGATGAACTCTTC
TTTAATAAGATTCAGGCCAGTCTTGGTGGGTGTGTGCGGATGATTGTTACTGGAGCAGCCCCAGCATCACCAACAGTTCTGGGATTTCTC
CGGGCAGCTCTAGGGTGCCAGGTTTATGAAGGTTATGGCCAAACTGAGTGCACAGCTGGATGTACCTTCACCACTCCTGGCGACTGGACC
TCAGGGCACGTAGGGGCGCCACTTCCCTGCAATCATATCAAGCTCGTTGATGTTGAGGAACTGAACTACTGGGCCTGCAAAGGAGAGGGA
GAGATATGTGTGAGAGGACCAAATGTGTTCAAAGGCTACTTGAAAGATCCAGACAGGACGAAGGAGGCCCTGGACAGCGATGGCTGGCTT
CACACTGGAGACATCGGAAAATGGCTGCCGGCAGGAACTCTTAAAATTATTGATCGGAAAAAGCATATATTTAAACTTGCTCAGGGAGAA
TATGTTGCACCCGAGAAGATTGAGAACATCTACATCCGGAGCCAACCTGTGGCGCAAATCTATGTCCATGGGGACAGCTTAAAGGCCTTT
TTGGTAGGCATTGTTGTGCCTGACCCTGAAGTTATGCCCTCCTGGGCCCAGAAGAGAGGAATTGAAGGAACATATGCAGATCTCTGCACA
AATAAGGATCTGAAGAAAGCCATTTTGGAAGATATGGTGAGGTTAGGAAAAGAAAGTGGACTCCATTCTTTTGAGCAGGTTAAAGCCATT
CACATCCATTCTGACATGTTCTCAGTTCAAAATGGCTTGCTGACACCAACACTAAAAGCTAAGAGACCTGAGCTGAGAGAGTACTTCAAA
AAACAAATAGAAGAGCTTTACTCAATCTCCATGTGAAGTTCAAGGAAAGTTCTTCTCAGTGTAATGAACTGTCTAGCAATATTATAGTTA
TTCTTGAAAGTAATGAGTCAAAATGACACAGCTGAAAATGAATAAGCATCTGATTTTATGACTGAGCCTTTTCCTGTCCCAAGAGGTCTT
TAACAATATTTTCTCTATCATCAATGAGTATATTTTATTTTTATTATAAAAATGATATTGTGGTGGACTGCTAAAAATATCACAAATGGC
AATGTAAAAATCAAGACATTTTCTCAAGAACTGTGTACCACTAAAAGTAATATATTGTCAATGTTCACAGAACTATTAAACATAAAGGAA

>66353_66353_3_PLIN1-ACSL6_PLIN1_chr15_90212731_ENST00000430628_ACSL6_chr5_131321151_ENST00000379246_length(amino acids)=691AA_BP=257
MAVNKGLTLLDGDLPEQENVLQRVLQLPVVSGTCECFQKTYTSTKEAHPLVASVCNAYEKGVQSASSLAAWSMEPVVRRLSTQFTAANEL
ACRGLDHLEEKIPALQYPPEKIASELKDTISTRLRSARNSISVPIASTSDKVLGAALAGCELAWGVARDTAEFAANTRAGRLASGGADLA
LGSIEKVVEYLLPPDKEESAPAPGHQQAQKSPKAKPSLLSRVGALTNTLSRYTVQTMARALEQGHTVAMWIPGVVPLPPQPDDLSIVCFT
SGTTGNPKGAMLTHGNVVADFSGFLKVTEKVIFPRQDDVLISFLPLAHMFERVIQSVVYCHGGRVGFFQGDIRLLSDDMKALCPTIFPVV
PRLLNRMYDKIFSQANTPLKRWLLEFAAKRKQAEVRSGIIRNDSIWDELFFNKIQASLGGCVRMIVTGAAPASPTVLGFLRAALGCQVYE
GYGQTECTAGCTFTTPGDWTSGHVGAPLPCNHIKLVDVEELNYWACKGEGEICVRGPNVFKGYLKDPDRTKEALDSDGWLHTGDIGKWLP
AGTLKIIDRKKHIFKLAQGEYVAPEKIENIYIRSQPVAQIYVHGDSLKAFLVGIVVPDPEVMPSWAQKRGIEGTYADLCTNKDLKKAILE

--------------------------------------------------------------
>66353_66353_4_PLIN1-ACSL6_PLIN1_chr15_90212731_ENST00000430628_ACSL6_chr5_131321151_ENST00000379249_length(transcript)=2106nt_BP=891nt
TGGAAGCAGCATTGCCCAAGCCTCCCAGGAGTGACAGGAATTGTTTCTGCCTGAGGAGACACTCTGCAGCCTGGGCTCTGTGAGACTGAG
GTGGCGGTCAGCCGGACTTGAGGAGCGAGGATGGCAGTCAACAAAGGCCTCACCTTGCTGGATGGAGACCTCCCTGAGCAGGAGAATGTG
CTGCAGCGGGTCCTGCAGCTGCCGGTGGTGAGTGGCACCTGCGAATGCTTCCAGAAGACCTACACCAGCACTAAGGAAGCCCACCCCCTG
GTGGCCTCTGTGTGCAATGCCTATGAGAAGGGCGTGCAGAGCGCCAGTAGCTTGGCTGCCTGGAGCATGGAGCCGGTGGTCCGCAGGCTG
TCCACCCAGTTCACAGCTGCCAATGAGCTGGCCTGCCGAGGCTTGGACCACCTGGAGGAAAAGATCCCCGCCCTCCAGTACCCCCCTGAA
AAGATTGCTTCTGAGCTGAAGGACACCATCTCCACCCGCCTCCGCAGTGCCAGAAACAGCATCAGCGTTCCCATCGCGAGCACTTCAGAC
AAGGTCCTGGGGGCCGCTTTGGCCGGGTGCGAGCTTGCCTGGGGGGTGGCCAGAGACACTGCGGAATTTGCTGCCAACACTCGAGCTGGC
CGACTGGCTTCTGGAGGGGCCGACTTGGCCTTGGGCAGCATTGAGAAGGTGGTGGAGTACCTCCTCCCTCCAGACAAGGAAGAGTCAGCC
CCTGCTCCTGGACACCAGCAAGCCCAGAAGTCTCCCAAGGCCAAGCCAAGCCTCTTGAGCAGGGTTGGGGCTCTGACCAACACCCTCTCT
CGATACACCGTGCAGACCATGGCCCGGGCCCTGGAGCAGGGCCACACCGTGGCCATGTGGATCCCAGGCGTGGTGCCCCTGCCCCCGCAG
CCTGATGACCTCTCCATTGTGTGTTTCACAAGCGGCACGACAGGGAACCCAAAAGGTGCGATGCTCACCCATGGGAACGTGGTGGCTGAT
TTCTCAGGCTTTCTGAAAGTGACAGAGAGTCAGTGGGCTCCCACTTGTGCGGATGTGCACATTTCCTATTTGCCTTTAGCACACATGTTT
GAGCGAATGGTGCAGTCTGTCGTCTATTGCCACGGAGGGCGTGTTGGCTTCTTCCAGGGAGATATCCGCCTTCTCTCAGATGACATGAAG
GCTCTATGCCCCACCATCTTCCCTGTGGTCCCACGACTGCTGAACCGGATGTACGACAAGATCTTCAGCCAGGCAAACACACCATTAAAG
CGCTGGCTCCTGGAGTTTGCAGCAAAGCGTAAGCAAGCCGAGGTCCGGAGTGGAATCATCAGGAATGATAGTATCTGGGATGAACTCTTC
TTTAATAAGATTCAGGCCAGTCTTGGTGGGTGTGTGCGGATGATTGTTACTGGAGCAGCCCCAGCATCACCAACAGTTCTGGGATTTCTC
CGGGCAGCTCTAGGGTGCCAGGTTTATGAAGGTTATGGCCAAACTGAGTGCACAGCTGGATGTACCTTCACCACTCCTGGCGACTGGACC
TCAGGGCACGTAGGGGCGCCACTTCCCTGCAATCATATCAAGCTCGTTGATGTTGAGGAACTGAACTACTGGGCCTGCAAAGGAGAGGGA
GAGATATGTGTGAGAGGACCAAATGTGTTCAAAGGCTACTTGAAAGATCCAGACAGGACGAAGGAGGCCCTGGACAGCGATGGCTGGCTT
CACACTGGAGACATCGGAAAATGGCTGCCGGCAGGAACTCTTAAAATTATTGATCGGAAAAAGCATATATTTAAACTTGCTCAGGGAGAA
TATGTTGCACCCGAGAAGATTGAGAACATCTACATCCGGAGCCAACCTGTGGCGCAAATCTATGTCCATGGGGACAGCTTAAAGGCCTTT
TTGGTAGGCATTGTTGTGCCTGACCCTGAAGTTATGCCCTCCTGGGCCCAGAAGAGAGGAATTGAAGGAACATATGCAGATCTCTGCACA
AATAAGGATCTGAAGAAAGCCATTTTGGAAGATATGGTGAGGTTAGGAAAAGAAAGTGGACTCCATTCTTTTGAGCAGGACCTACCACAG

>66353_66353_4_PLIN1-ACSL6_PLIN1_chr15_90212731_ENST00000430628_ACSL6_chr5_131321151_ENST00000379249_length(amino acids)=661AA_BP=257
MAVNKGLTLLDGDLPEQENVLQRVLQLPVVSGTCECFQKTYTSTKEAHPLVASVCNAYEKGVQSASSLAAWSMEPVVRRLSTQFTAANEL
ACRGLDHLEEKIPALQYPPEKIASELKDTISTRLRSARNSISVPIASTSDKVLGAALAGCELAWGVARDTAEFAANTRAGRLASGGADLA
LGSIEKVVEYLLPPDKEESAPAPGHQQAQKSPKAKPSLLSRVGALTNTLSRYTVQTMARALEQGHTVAMWIPGVVPLPPQPDDLSIVCFT
SGTTGNPKGAMLTHGNVVADFSGFLKVTESQWAPTCADVHISYLPLAHMFERMVQSVVYCHGGRVGFFQGDIRLLSDDMKALCPTIFPVV
PRLLNRMYDKIFSQANTPLKRWLLEFAAKRKQAEVRSGIIRNDSIWDELFFNKIQASLGGCVRMIVTGAAPASPTVLGFLRAALGCQVYE
GYGQTECTAGCTFTTPGDWTSGHVGAPLPCNHIKLVDVEELNYWACKGEGEICVRGPNVFKGYLKDPDRTKEALDSDGWLHTGDIGKWLP
AGTLKIIDRKKHIFKLAQGEYVAPEKIENIYIRSQPVAQIYVHGDSLKAFLVGIVVPDPEVMPSWAQKRGIEGTYADLCTNKDLKKAILE

--------------------------------------------------------------
>66353_66353_5_PLIN1-ACSL6_PLIN1_chr15_90212731_ENST00000430628_ACSL6_chr5_131321151_ENST00000379255_length(transcript)=2412nt_BP=891nt
TGGAAGCAGCATTGCCCAAGCCTCCCAGGAGTGACAGGAATTGTTTCTGCCTGAGGAGACACTCTGCAGCCTGGGCTCTGTGAGACTGAG
GTGGCGGTCAGCCGGACTTGAGGAGCGAGGATGGCAGTCAACAAAGGCCTCACCTTGCTGGATGGAGACCTCCCTGAGCAGGAGAATGTG
CTGCAGCGGGTCCTGCAGCTGCCGGTGGTGAGTGGCACCTGCGAATGCTTCCAGAAGACCTACACCAGCACTAAGGAAGCCCACCCCCTG
GTGGCCTCTGTGTGCAATGCCTATGAGAAGGGCGTGCAGAGCGCCAGTAGCTTGGCTGCCTGGAGCATGGAGCCGGTGGTCCGCAGGCTG
TCCACCCAGTTCACAGCTGCCAATGAGCTGGCCTGCCGAGGCTTGGACCACCTGGAGGAAAAGATCCCCGCCCTCCAGTACCCCCCTGAA
AAGATTGCTTCTGAGCTGAAGGACACCATCTCCACCCGCCTCCGCAGTGCCAGAAACAGCATCAGCGTTCCCATCGCGAGCACTTCAGAC
AAGGTCCTGGGGGCCGCTTTGGCCGGGTGCGAGCTTGCCTGGGGGGTGGCCAGAGACACTGCGGAATTTGCTGCCAACACTCGAGCTGGC
CGACTGGCTTCTGGAGGGGCCGACTTGGCCTTGGGCAGCATTGAGAAGGTGGTGGAGTACCTCCTCCCTCCAGACAAGGAAGAGTCAGCC
CCTGCTCCTGGACACCAGCAAGCCCAGAAGTCTCCCAAGGCCAAGCCAAGCCTCTTGAGCAGGGTTGGGGCTCTGACCAACACCCTCTCT
CGATACACCGTGCAGACCATGGCCCGGGCCCTGGAGCAGGGCCACACCGTGGCCATGTGGATCCCAGGCGTGGTGCCCCTGCCCCCGCAG
CCTGATGACCTCTCCATTGTGTGTTTCACAAGCGGCACGACAGGGAACCCAAAAGGTGCGATGCTCACCCATGGGAACGTGGTGGCTGAT
TTCTCAGGCTTTCTGAAAGTGACAGAGGGAGATATCCGCCTTCTCTCAGATGACATGAAGGCTCTATGCCCCACCATCTTCCCTGTGGTC
CCACGACTGCTGAACCGGATGTACGACAAGATCTTCAGCCAGGCAAACACACCATTAAAGCGCTGGCTCCTGGAGTTTGCAGCAAAGCGT
AAGCAAGCCGAGGTCCGGAGTGGAATCATCAGGAATGATAGTATCTGGGATGAACTCTTCTTTAATAAGATTCAGGCCAGTCTTGGTGGG
TGTGTGCGGATGATTGTTACTGGAGCAGCCCCAGCATCACCAACAGTTCTGGGATTTCTCCGGGCAGCTCTAGGGTGCCAGGTTTATGAA
GGTTATGGCCAAACTGAGTGCACAGCTGGATGTACCTTCACCACTCCTGGCGACTGGACCTCAGGGCACGTAGGGGCGCCACTTCCCTGC
AATCATATCAAGCTCGTTGATGTTGAGGAACTGAACTACTGGGCCTGCAAAGGAGAGGGAGAGATATGTGTGAGAGGACCAAATGTGTTC
AAAGGCTACTTGAAAGATCCAGACAGGACGAAGGAGGCCCTGGACAGCGATGGCTGGCTTCACACTGGAGACATCGGAAAATGGCTGCCG
GCAGGAACTCTTAAAATTATTGATCGGAAAAAGCATATATTTAAACTTGCTCAGGGAGAATATGTTGCACCCGAGAAGATTGAGAACATC
TACATCCGGAGCCAACCTGTGGCGCAAATCTATGTCCATGGGGACAGCTTAAAGGCCTTTTTGGTAGGCATTGTTGTGCCTGACCCTGAA
GTTATGCCCTCCTGGGCCCAGAAGAGAGGAATTGAAGGAACATATGCAGATCTCTGCACAAATAAGGATCTGAAGAAAGCCATTTTGGAA
GATATGGTGAGGTTAGGAAAAGAAAGTGGACTCCATTCTTTTGAGCAGGTTAAAGCCATTCACATCCATTCTGACATGTTCTCAGTTCAA
AATGGCTTGCTGACACCAACACTAAAAGCTAAGAGACCTGAGCTGAGAGAGTACTTCAAAAAACAAATAGAAGAGCTTTACTCAATCTCC
ATGTGAAGTTCAAGGAAAGTTCTTCTCAGTGTAATGAACTGTCTAGCAATATTATAGTTATTCTTGAAAGTAATGAGTCAAAATGACACA
GCTGAAAATGAATAAGCATCTGATTTTATGACTGAGCCTTTTCCTGTCCCAAGAGGTCTTTAACAATATTTTCTCTATCATCAATGAGTA
TATTTTATTTTTATTATAAAAATGATATTGTGGTGGACTGCTAAAAATATCACAAATGGCAATGTAAAAATCAAGACATTTTCTCAAGAA

>66353_66353_5_PLIN1-ACSL6_PLIN1_chr15_90212731_ENST00000430628_ACSL6_chr5_131321151_ENST00000379255_length(amino acids)=651AA_BP=257
MAVNKGLTLLDGDLPEQENVLQRVLQLPVVSGTCECFQKTYTSTKEAHPLVASVCNAYEKGVQSASSLAAWSMEPVVRRLSTQFTAANEL
ACRGLDHLEEKIPALQYPPEKIASELKDTISTRLRSARNSISVPIASTSDKVLGAALAGCELAWGVARDTAEFAANTRAGRLASGGADLA
LGSIEKVVEYLLPPDKEESAPAPGHQQAQKSPKAKPSLLSRVGALTNTLSRYTVQTMARALEQGHTVAMWIPGVVPLPPQPDDLSIVCFT
SGTTGNPKGAMLTHGNVVADFSGFLKVTEGDIRLLSDDMKALCPTIFPVVPRLLNRMYDKIFSQANTPLKRWLLEFAAKRKQAEVRSGII
RNDSIWDELFFNKIQASLGGCVRMIVTGAAPASPTVLGFLRAALGCQVYEGYGQTECTAGCTFTTPGDWTSGHVGAPLPCNHIKLVDVEE
LNYWACKGEGEICVRGPNVFKGYLKDPDRTKEALDSDGWLHTGDIGKWLPAGTLKIIDRKKHIFKLAQGEYVAPEKIENIYIRSQPVAQI
YVHGDSLKAFLVGIVVPDPEVMPSWAQKRGIEGTYADLCTNKDLKKAILEDMVRLGKESGLHSFEQVKAIHIHSDMFSVQNGLLTPTLKA

--------------------------------------------------------------
>66353_66353_6_PLIN1-ACSL6_PLIN1_chr15_90212731_ENST00000430628_ACSL6_chr5_131321151_ENST00000379264_length(transcript)=6457nt_BP=891nt
TGGAAGCAGCATTGCCCAAGCCTCCCAGGAGTGACAGGAATTGTTTCTGCCTGAGGAGACACTCTGCAGCCTGGGCTCTGTGAGACTGAG
GTGGCGGTCAGCCGGACTTGAGGAGCGAGGATGGCAGTCAACAAAGGCCTCACCTTGCTGGATGGAGACCTCCCTGAGCAGGAGAATGTG
CTGCAGCGGGTCCTGCAGCTGCCGGTGGTGAGTGGCACCTGCGAATGCTTCCAGAAGACCTACACCAGCACTAAGGAAGCCCACCCCCTG
GTGGCCTCTGTGTGCAATGCCTATGAGAAGGGCGTGCAGAGCGCCAGTAGCTTGGCTGCCTGGAGCATGGAGCCGGTGGTCCGCAGGCTG
TCCACCCAGTTCACAGCTGCCAATGAGCTGGCCTGCCGAGGCTTGGACCACCTGGAGGAAAAGATCCCCGCCCTCCAGTACCCCCCTGAA
AAGATTGCTTCTGAGCTGAAGGACACCATCTCCACCCGCCTCCGCAGTGCCAGAAACAGCATCAGCGTTCCCATCGCGAGCACTTCAGAC
AAGGTCCTGGGGGCCGCTTTGGCCGGGTGCGAGCTTGCCTGGGGGGTGGCCAGAGACACTGCGGAATTTGCTGCCAACACTCGAGCTGGC
CGACTGGCTTCTGGAGGGGCCGACTTGGCCTTGGGCAGCATTGAGAAGGTGGTGGAGTACCTCCTCCCTCCAGACAAGGAAGAGTCAGCC
CCTGCTCCTGGACACCAGCAAGCCCAGAAGTCTCCCAAGGCCAAGCCAAGCCTCTTGAGCAGGGTTGGGGCTCTGACCAACACCCTCTCT
CGATACACCGTGCAGACCATGGCCCGGGCCCTGGAGCAGGGCCACACCGTGGCCATGTGGATCCCAGGCGTGGTGCCCCTGCCCCCGCAG
CCTGATGACCTCTCCATTGTGTGTTTCACAAGCGGCACGACAGGGAACCCAAAAGGTGCGATGCTCACCCATGGGAACGTGGTGGCTGAT
TTCTCAGGCTTTCTGAAAGTGACAGAGAAAGTGATCTTTCCGAGACAGGACGATGTGCTCATCTCCTTCCTGCCTCTGGCTCACATGTTT
GAGAGAGTAATCCAGTCTGTCGTCTATTGCCACGGAGGGCGTGTTGGCTTCTTCCAGGGAGATATCCGCCTTCTCTCAGATGACATGAAG
GCTCTATGCCCCACCATCTTCCCTGTGGTCCCACGACTGCTGAACCGGATGTACGACAAGATCTTCAGCCAGGCAAACACACCATTAAAG
CGCTGGCTCCTGGAGTTTGCAGCAAAGCGTAAGCAAGCCGAGGTCCGGAGTGGAATCATCAGGAATGATAGTATCTGGGATGAACTCTTC
TTTAATAAGATTCAGGCCAGTCTTGGTGGGTGTGTGCGGATGATTGTTACTGGAGCAGCCCCAGCATCACCAACAGTTCTGGGATTTCTC
CGGGCAGCTCTAGGGTGCCAGGTTTATGAAGGTTATGGCCAAACTGAGTGCACAGCTGGATGTACCTTCACCACTCCTGGCGACTGGACC
TCAGGGCACGTAGGGGCGCCACTTCCCTGCAATCATATCAAGCTCGTTGATGTTGAGGAACTGAACTACTGGGCCTGCAAAGGAGAGGGA
GAGATATGTGTGAGAGGACCAAATGTGTTCAAAGGCTACTTGAAAGATCCAGACAGGACGAAGGAGGCCCTGGACAGCGATGGCTGGCTT
CACACTGGAGACATCGGAAAATGGCTGCCGGCAGGAACTCTTAAAATTATTGATCGGAAAAAGCATATATTTAAACTTGCTCAGGGAGAA
TATGTTGCACCCGAGAAGATTGAGAACATCTACATCCGGAGCCAACCTGTGGCGCAAATCTATGTCCATGGGGACAGCTTAAAGGCCTTT
TTGGTAGGCATTGTTGTGCCTGACCCTGAAGTTATGCCCTCCTGGGCCCAGAAGAGAGGAATTGAAGGAACATATGCAGATCTCTGCACA
AATAAGGATCTGAAGAAAGCCATTTTGGAAGATATGGTGAGGTTAGGAAAAGAAAGTGGACTCCATTCTTTTGAGCAGGTTAAAGCCATT
CACATCCATTCTGACATGTTCTCAGTTCAAAATGGCTTGCTGACACCAACACTAAAAGCTAAGAGACCTGAGCTGAGAGAGTACTTCAAA
AAACAAATAGAAGAGCTTTACTCAATCTCCATGTGAAGTTCAAGGAAAGTTCTTCTCAGTGTAATGAACTGTCTAGCAATATTATAGTTA
TTCTTGAAAGTAATGAGTCAAAATGACACAGCTGAAAATGAATAAGCATCTGATTTTATGACTGAGCCTTTTCCTGTCCCAAGAGGTCTT
TAACAATATTTTCTCTATCATCAATGAGTATATTTTATTTTTATTATAAAAATGATATTGTGGTGGACTGCTAAAAATATCACAAATGGC
AATGTAAAAATCAAGACATTTTCTCAAGAACTGTGTACCACTAAAAGTAATATATTGTCAATGTTCACAGAACTATTAAACATAAAGGAA
AAACATAAGTGATATATTCTACTTAATTATTTGTGAATCAGTAACCAGATGCAGCAAATATCTAGGCAATGTGGACTACCTCATTCAGTA
ACTGATTGTCAAAATCACAATTAAATCAGACTTCAAAAATTAAAGCTAGGTGTATAGAATCATGCTAAAAGAAAACATGATAACTCATAG
TCTACGTAACTTCAGAGTCTTTAAACATGACAATCCACATTGTCATATGTGAAAATTTTCTCTCTGATTTTTACTTTCATTCATGAAAAA
TGAAAATTCAGAAATTCTTTTTTTCCTTTTTGTTTTGAGACAGGGTCTGCTCTGTCACCTAGGCTGGAGTGCAGTGGCTTAATCATGGCT
CATTGCAGTCTCCATCTCCTGGGCTCGAGTGATCCTCCTGTCTCACCTCCCAAGTAGCTGAGACTACAGTACAGGCACATGCCACCACAC
CTGGCTAATAGAAATTTTTTTTTTAGAGATTTTGCTCAGGCTGGTCTCAAACTCCTGAGCTCAAGGGATCCTCCCGCCTTGGCCTCCCTA
AGTGCTAGGATTACAGGCATGAGCCATTGTTCCCAGCCAAATTCAGATATTATTAAAACACATGTCATATTTATATAGTAACTTACAAAG
ACCTTTCAATACATTTTCTCATTTATTAAGCTCATTAAAGTATTCAGGAACTACCTAGAAAAAATATAATGTAAAACTATTCAAGGATAG
TGTGTGTATGTTCATGGACTTCTTATTATAATGAATTCTAAAAGACATCTGTTGACTCTACAATGAATGGATCCTTGAGGAATACTTGGG
AGAAGAAACTCAGAGTTATTTCTCAGGGTAGGCAGCAATTAATGTACCTACATTCCTTGCTGGGGTCTTCTAGTCTTCCATTCCCAATGT
GCCCATGCTATGCCTGGAAACCCTATATGGTTGTAATTCTGAACAATTTCACTTTTTTTCCAGTAAGAATATCAAGGCAGAAGGTGGGAA
GGAGGGGACATTATTTCCAGGGAAAATAGTTTTTCAACAATATAACTTTGATAAACCTCTTTAAAATGCCCCAAGAAAACTTTTTAAGTC
CATAGACAAAGAAATACTGCCTAATGGCATAATTACATTCCTAAAATCTTTAAGCGTGCCGAAGTTTAACCACTAAAACCTCCTTTCTTG
CATTATGTATTTAGATGCACCCTGTATTGGGGTGTCAACAATTTCTTATAATTAAAGGCCAGATACCATGGACAGCAATTAAGTTCCAAG
CTATAGATTGTGCCTCTGAAAAAGGCATGGACCCCAGGAACGTGTTTTTCTTCTGTAGAGACAAGACTCTAAAAGCATATCAACAATCCA
TATGCAATTCATGTGTTAATTTAAAATGTATGTGCTCAGTGTTTGTAGTCTAGAAGCTCCTTTCCCTTGGAGGAATGCCAAGCAGTTTGC
AAAAATAAATGCTGTTAGTTAAAAACCACATAATCACATGGGCCTACTGAATAAATATGCATCAGTGATTATATACTTATATTTCAGTCT
TGTCAAAAGTGAATCACTGTTTCATTTGATGTATTTACCCAGTCTTTTTATCCAGTTTTTCTTGGGCATATTCTCTCTGAAGACCCACTG
TTGCACTTCTAAATTTGACAGTTAAGAAATGAGCTAGTTCTATACACACTGATTTTTAAAGGCGTTTCTGAATAAACTAATACTTAAAAT
GTCCAAAGTCACATCTGTACAGCATTAGATTTTTATATTTAATATATATTTGACTAATTAAAAGTGAAAGTTGTTACCTGAACTGGATAT
TCATACTATTTTAAGGGCAAGTTGCTTACATTTCAATAACAACAAAAAAAGAATCTGTTTCCCATTGTCCTCCTACTCAACTAAAATTCA
TAGTTGGCTTTAAGCCCAAAAGAATTTTGAACAATGTGACAGAAACAAGTAATGTAAAACTTATTTTGTTTTATTTATACTTTATAATAG
TTAGATATAACAGATTATGGACAACTTAATATTTCTTCTTTTTGGCTGGGCGCGGTGGCTCATGCCTGTAATCCCAGCACTTTGGGAGGC
CGAGGCGGGCAGATCACGAAGTCAGGAGATCGAGACCATCCTGGCTAACACAGTGAAACCCCGTCTCTACTAAAAAAATACAAAAAATTA
GCCGGGCGTTGTGGCGGGCGCCTGTAGTCCCAGCTACTCGGGAGGCTGAGGCAGGAGAATGGCATGAACCTGGGAGGCGGAGCTTGCAGT
GAGCCGAGATCCCGCCACTGTACTCCAGCCTGGGCAACAGAACGAGACTCCGTCTCAAAAAGAAAGAAAAAAAAAAAACAAAAACAAGGT
TTCTTCTTTTTGCCACTTAAAATATCTTATATTTCTAGATTTCCAGGTCTATGTGGAAATCATCACACTTGGGCCAATAAATGGGTTAGT
TCAGATGTGCTGAGAAAAGTAAATAGTGTACCCTAAATATCTTGCATGTACATTTATCTATTTCTCTGTTTAATGCCACTTAATTTTGTA
AGAAATGAGAAATGAAACCCTATGTATCAGTGGAAAAATCCTTCTTGCTTCAGATTTCCCAACTTTATTCTGGAGGAGAAAAAAATCTGT
ATTTCTCATTAACAGAGATAGAAAAAGGTGATGTACTTACGATGGTCACATTCATATTGGGCATTGGATCTATTTAAGCCTAGAAGTATA
ACAGATAATCAGTTCCTTAAGTGTAAATATGTTCTTAAATGTTTGGCCTTTTTATCTGTTATTCAAATGTATTAGTAATTCTCATATTTT
GCAAACAGATCCTTTTGTGTATATTATAAAATATATACCAAATCTGTTTTTCCTTTTGCTGTGGAAGATGTCTTTATATAATATTGAGAC
TTCCCTTGCAAATGAGAGACGGGACTCTGGTCAGGTATAGTGTGTAGGCCTAGCCCCATGTATTAGGAACTCATAAACTCAGAAATCCAA
GGATTAAACATTTTATGTCTCCTTCATTTATGCAAGTCATGCTTTCATTCTACATGTAGTTAAAACTACAAGTATGAGAAAAAATAGAAC
TTTCCATTGGAATTTTTTCCAATCAGGTAATGTTTTAGCAACTTGAAATCAGCACTTAATTTGATTGTATTACCTATCAAAGAACCAATA
ACCTTTCCTTTTTCTGCAGTAAAGAAAATGAAATATCCTTTATTTTCCAAATGTATGAAGCACAAATGCAATATAGTTATTTAAAATATA
AAATACTTTAAAATGAATGTGAAGAATGGGAAAATATATTTTTGCATGAAAACAGACTACTTACAAATGTGCTTAATATCTCAGGAAAAA
AAGAATGAATAACCGTATATAAAATTGGTAAACTATAAATTGGCTGTATTTCCTTGCCGGTTTTAATTTTAAGGAAGCATTTACATGAAA
AGAAAAAAGGATCCTAGTAGTCTGAATTTCCTCTCAAGTATGCTAGAAAATACTTTCTATGAATTTACAATTAACTGCAATAAGAAGTGG
GTTAGCATTCAAGTAAGGTCAATACCCCAAATGAGAAACTCTTCAGTTAGAACACATTAGTGGTTGTAACACAGAGGCAGTAGATAAATA
TTTGAAATGTGAGCATTTCTAAACTTGGTACCAAATGGAAAGGGTTTCATGAGGTGACAGTGGCTTTTAAACATTCATTTGACCGATTAT
TCTAATTTTCCTTGTTAAATCATTGCAACAGTTGCATGGGGGAGAATGGATATTTTTTGAAGAATTGCTTATTCCACTTTCAATTTTTAA
AAATCGAGGGGATTAAAATATTACTTTTTAAATATGCATAAAAGTATCTTAACTGTAATTACATTTTCAGTTGCTTTGTTATAGTAGCAT

>66353_66353_6_PLIN1-ACSL6_PLIN1_chr15_90212731_ENST00000430628_ACSL6_chr5_131321151_ENST00000379264_length(amino acids)=691AA_BP=257
MAVNKGLTLLDGDLPEQENVLQRVLQLPVVSGTCECFQKTYTSTKEAHPLVASVCNAYEKGVQSASSLAAWSMEPVVRRLSTQFTAANEL
ACRGLDHLEEKIPALQYPPEKIASELKDTISTRLRSARNSISVPIASTSDKVLGAALAGCELAWGVARDTAEFAANTRAGRLASGGADLA
LGSIEKVVEYLLPPDKEESAPAPGHQQAQKSPKAKPSLLSRVGALTNTLSRYTVQTMARALEQGHTVAMWIPGVVPLPPQPDDLSIVCFT
SGTTGNPKGAMLTHGNVVADFSGFLKVTEKVIFPRQDDVLISFLPLAHMFERVIQSVVYCHGGRVGFFQGDIRLLSDDMKALCPTIFPVV
PRLLNRMYDKIFSQANTPLKRWLLEFAAKRKQAEVRSGIIRNDSIWDELFFNKIQASLGGCVRMIVTGAAPASPTVLGFLRAALGCQVYE
GYGQTECTAGCTFTTPGDWTSGHVGAPLPCNHIKLVDVEELNYWACKGEGEICVRGPNVFKGYLKDPDRTKEALDSDGWLHTGDIGKWLP
AGTLKIIDRKKHIFKLAQGEYVAPEKIENIYIRSQPVAQIYVHGDSLKAFLVGIVVPDPEVMPSWAQKRGIEGTYADLCTNKDLKKAILE

--------------------------------------------------------------
>66353_66353_7_PLIN1-ACSL6_PLIN1_chr15_90212731_ENST00000430628_ACSL6_chr5_131321151_ENST00000379272_length(transcript)=4826nt_BP=891nt
TGGAAGCAGCATTGCCCAAGCCTCCCAGGAGTGACAGGAATTGTTTCTGCCTGAGGAGACACTCTGCAGCCTGGGCTCTGTGAGACTGAG
GTGGCGGTCAGCCGGACTTGAGGAGCGAGGATGGCAGTCAACAAAGGCCTCACCTTGCTGGATGGAGACCTCCCTGAGCAGGAGAATGTG
CTGCAGCGGGTCCTGCAGCTGCCGGTGGTGAGTGGCACCTGCGAATGCTTCCAGAAGACCTACACCAGCACTAAGGAAGCCCACCCCCTG
GTGGCCTCTGTGTGCAATGCCTATGAGAAGGGCGTGCAGAGCGCCAGTAGCTTGGCTGCCTGGAGCATGGAGCCGGTGGTCCGCAGGCTG
TCCACCCAGTTCACAGCTGCCAATGAGCTGGCCTGCCGAGGCTTGGACCACCTGGAGGAAAAGATCCCCGCCCTCCAGTACCCCCCTGAA
AAGATTGCTTCTGAGCTGAAGGACACCATCTCCACCCGCCTCCGCAGTGCCAGAAACAGCATCAGCGTTCCCATCGCGAGCACTTCAGAC
AAGGTCCTGGGGGCCGCTTTGGCCGGGTGCGAGCTTGCCTGGGGGGTGGCCAGAGACACTGCGGAATTTGCTGCCAACACTCGAGCTGGC
CGACTGGCTTCTGGAGGGGCCGACTTGGCCTTGGGCAGCATTGAGAAGGTGGTGGAGTACCTCCTCCCTCCAGACAAGGAAGAGTCAGCC
CCTGCTCCTGGACACCAGCAAGCCCAGAAGTCTCCCAAGGCCAAGCCAAGCCTCTTGAGCAGGGTTGGGGCTCTGACCAACACCCTCTCT
CGATACACCGTGCAGACCATGGCCCGGGCCCTGGAGCAGGGCCACACCGTGGCCATGTGGATCCCAGGCGTGGTGCCCCTGCCCCCGCAG
CCTGATGACCTCTCCATTGTGTGTTTCACAAGCGGCACGACAGGGAACCCAAAAGGTGCGATGCTCACCCATGGGAACGTGGTGGCTGAT
TTCTCAGGCTTTCTGAAAGTGACAGAGAAAGTGATCTTTCCGAGACAGGACGATGTGCTCATCTCCTTCCTGCCTCTGGCTCACATGTTT
GAGAGAGTAATCCAGTCTGTCGTCTATTGCCACGGAGGGCGTGTTGGCTTCTTCCAGGGAGATATCCGCCTTCTCTCAGATGACATGAAG
GCTCTATGCCCCACCATCTTCCCTGTGGTCCCACGACTGCTGAACCGGATGTACGACAAGATCTTCAGCCAGGCAAACACACCATTAAAG
CGCTGGCTCCTGGAGTTTGCAGCAAAGCGTAAGCAAGCCGAGGTCCGGAGTGGAATCATCAGGAATGATAGTATCTGGGATGAACTCTTC
TTTAATAAGATTCAGGCCAGTCTTGGTGGGTGTGTGCGGATGATTGTTACTGGAGCAGCCCCAGCATCACCAACAGTTCTGGGATTTCTC
CGGGCAGCTCTAGGGTGCCAGGTTTATGAAGGTTATGGCCAAACTGAGTGCACAGCTGGATGTACCTTCACCACTCCTGGCGACTGGACC
TCAGGGCACGTAGGGGCGCCACTTCCCTGCAATCATATCAAGCTCGTTGATGTTGAGGAACTGAACTACTGGGCCTGCAAAGGAGAGGGA
GAGATATGTGTGAGAGGACCAAATGTGTTCAAAGGCTACTTGAAAGATCCAGACAGGACGAAGGAGGCCCTGGACAGCGATGGCTGGCTT
CACACTGGAGACATCGGAAAATGGCTGCCGGCAGGAACTCTTAAAATTATTGATCGGAAAAAGCATATATTTAAACTTGCTCAGGGAGAA
TATGTTGCACCCGAGAAGATTGAGAACATCTACATCCGGAGCCAACCTGTGGCGCAAATCTATGTCCATGGGGACAGCTTAAAGGCCTTT
TTGGTAGGCATTGTTGTGCCTGACCCTGAAGTTATGCCCTCCTGGGCCCAGAAGAGAGGAATTGAAGGAACATATGCAGATCTCTGCACA
AATAAGGATCTGAAGAAAGCCATTTTGGAAGATATGGTGAGGTTAGGAAAAGAAAGTGGACTCCATTCTTTTGAGCAGGTTAAAGCCATT
CACATCCATTCTGACATGTTCTCAGTTCAAAATGGCTTGCTGACACCAACACTAAAAGCTAAGAGACCTGAGCTGAGAGAGTACTTCAAA
AAACAAATAGAAGAGCTTTACTCAATCTCCATGTGAAGTTCAAGGAAAGTTCTTCTCAGTGTAATGAACTGTCTAGCAATATTATAGTTA
TTCTTGAAAGTAATGAGTCAAAATGACACAGCTGAAAATGAATAAGCATCTGATTTTATGACTGAGCCTTTTCCTGTCCCAAGAGGTCTT
TAACAATATTTTCTCTATCATCAATGAGTATATTTTATTTTTATTATAAAAATGATATTGTGGTGGACTGCTAAAAATATCACAAATGGC
AATGTAAAAATCAAGACATTTTCTCAAGAACTGTGTACCACTAAAAGTAATATATTGTCAATGTTCACAGAACTATTAAACATAAAGGAA
AAACATAAGTGATATATTCTACTTAATTATTTGTGAATCAGTAACCAGATGCAGCAAATATCTAGGCAATGTGGACTACCTCATTCAGTA
ACTGATTGTCAAAATCACAATTAAATCAGACTTCAAAAATTAAAGCTAGGTGTATAGAATCATGCTAAAAGAAAACATGATAACTCATAG
TCTACGTAACTTCAGAGTCTTTAAACATGACAATCCACATTGTCATATGTGAAAATTTTCTCTCTGATTTTTACTTTCATTCATGAAAAA
TGAAAATTCAGAAATTCTTTTTTTCCTTTTTGTTTTGAGACAGGGTCTGCTCTGTCACCTAGGCTGGAGTGCAGTGGCTTAATCATGGCT
CATTGCAGTCTCCATCTCCTGGGCTCGAGTGATCCTCCTGTCTCACCTCCCAAGTAGCTGAGACTACAGTACAGGCACATGCCACCACAC
CTGGCTAATAGAAATTTTTTTTTTAGAGATTTTGCTCAGGCTGGTCTCAAACTCCTGAGCTCAAGGGATCCTCCCGCCTTGGCCTCCCTA
AGTGCTAGGATTACAGGCATGAGCCATTGTTCCCAGCCAAATTCAGATATTATTAAAACACATGTCATATTTATATAGTAACTTACAAAG
ACCTTTCAATACATTTTCTCATTTATTAAGCTCATTAAAGTATTCAGGAACTACCTAGAAAAAATATAATGTAAAACTATTCAAGGATAG
TGTGTGTATGTTCATGGACTTCTTATTATAATGAATTCTAAAAGACATCTGTTGACTCTACAATGAATGGATCCTTGAGGAATACTTGGG
AGAAGAAACTCAGAGTTATTTCTCAGGGTAGGCAGCAATTAATGTACCTACATTCCTTGCTGGGGTCTTCTAGTCTTCCATTCCCAATGT
GCCCATGCTATGCCTGGAAACCCTATATGGTTGTAATTCTGAACAATTTCACTTTTTTTCCAGTAAGAATATCAAGGCAGAAGGTGGGAA
GGAGGGGACATTATTTCCAGGGAAAATAGTTTTTCAACAATATAACTTTGATAAACCTCTTTAAAATGCCCCAAGAAAACTTTTTAAGTC
CATAGACAAAGAAATACTGCCTAATGGCATAATTACATTCCTAAAATCTTTAAGCGTGCCGAAGTTTAACCACTAAAACCTCCTTTCTTG
CATTATGTATTTAGATGCACCCTGTATTGGGGTGTCAACAATTTCTTATAATTAAAGGCCAGATACCATGGACAGCAATTAAGTTCCAAG
CTATAGATTGTGCCTCTGAAAAAGGCATGGACCCCAGGAACGTGTTTTTCTTCTGTAGAGACAAGACTCTAAAAGCATATCAACAATCCA
TATGCAATTCATGTGTTAATTTAAAATGTATGTGCTCAGTGTTTGTAGTCTAGAAGCTCCTTTCCCTTGGAGGAATGCCAAGCAGTTTGC
AAAAATAAATGCTGTTAGTTAAAAACCACATAATCACATGGGCCTACTGAATAAATATGCATCAGTGATTATATACTTATATTTCAGTCT
TGTCAAAAGTGAATCACTGTTTCATTTGATGTATTTACCCAGTCTTTTTATCCAGTTTTTCTTGGGCATATTCTCTCTGAAGACCCACTG
TTGCACTTCTAAATTTGACAGTTAAGAAATGAGCTAGTTCTATACACACTGATTTTTAAAGGCGTTTCTGAATAAACTAATACTTAAAAT
GTCCAAAGTCACATCTGTACAGCATTAGATTTTTATATTTAATATATATTTGACTAATTAAAAGTGAAAGTTGTTACCTGAACTGGATAT
TCATACTATTTTAAGGGCAAGTTGCTTACATTTCAATAACAACAAAAAAAGAATCTGTTTCCCATTGTCCTCCTACTCAACTAAAATTCA
TAGTTGGCTTTAAGCCCAAAAGAATTTTGAACAATGTGACAGAAACAAGTAATGTAAAACTTATTTTGTTTTATTTATACTTTATAATAG
TTAGATATAACAGATTATGGACAACTTAATATTTCTTCTTTTTGGCTGGGCGCGGTGGCTCATGCCTGTAATCCCAGCACTTTGGGAGGC
CGAGGCGGGCAGATCACGAAGTCAGGAGATCGAGACCATCCTGGCTAACACAGTGAAACCCCGTCTCTACTAAAAAAATACAAAAAATTA
GCCGGGCGTTGTGGCGGGCGCCTGTAGTCCCAGCTACTCGGGAGGCTGAGGCAGGAGAATGGCATGAACCTGGGAGGCGGAGCTTGCAGT

>66353_66353_7_PLIN1-ACSL6_PLIN1_chr15_90212731_ENST00000430628_ACSL6_chr5_131321151_ENST00000379272_length(amino acids)=691AA_BP=257
MAVNKGLTLLDGDLPEQENVLQRVLQLPVVSGTCECFQKTYTSTKEAHPLVASVCNAYEKGVQSASSLAAWSMEPVVRRLSTQFTAANEL
ACRGLDHLEEKIPALQYPPEKIASELKDTISTRLRSARNSISVPIASTSDKVLGAALAGCELAWGVARDTAEFAANTRAGRLASGGADLA
LGSIEKVVEYLLPPDKEESAPAPGHQQAQKSPKAKPSLLSRVGALTNTLSRYTVQTMARALEQGHTVAMWIPGVVPLPPQPDDLSIVCFT
SGTTGNPKGAMLTHGNVVADFSGFLKVTEKVIFPRQDDVLISFLPLAHMFERVIQSVVYCHGGRVGFFQGDIRLLSDDMKALCPTIFPVV
PRLLNRMYDKIFSQANTPLKRWLLEFAAKRKQAEVRSGIIRNDSIWDELFFNKIQASLGGCVRMIVTGAAPASPTVLGFLRAALGCQVYE
GYGQTECTAGCTFTTPGDWTSGHVGAPLPCNHIKLVDVEELNYWACKGEGEICVRGPNVFKGYLKDPDRTKEALDSDGWLHTGDIGKWLP
AGTLKIIDRKKHIFKLAQGEYVAPEKIENIYIRSQPVAQIYVHGDSLKAFLVGIVVPDPEVMPSWAQKRGIEGTYADLCTNKDLKKAILE

--------------------------------------------------------------
>66353_66353_8_PLIN1-ACSL6_PLIN1_chr15_90212731_ENST00000430628_ACSL6_chr5_131321151_ENST00000543479_length(transcript)=2196nt_BP=891nt
TGGAAGCAGCATTGCCCAAGCCTCCCAGGAGTGACAGGAATTGTTTCTGCCTGAGGAGACACTCTGCAGCCTGGGCTCTGTGAGACTGAG
GTGGCGGTCAGCCGGACTTGAGGAGCGAGGATGGCAGTCAACAAAGGCCTCACCTTGCTGGATGGAGACCTCCCTGAGCAGGAGAATGTG
CTGCAGCGGGTCCTGCAGCTGCCGGTGGTGAGTGGCACCTGCGAATGCTTCCAGAAGACCTACACCAGCACTAAGGAAGCCCACCCCCTG
GTGGCCTCTGTGTGCAATGCCTATGAGAAGGGCGTGCAGAGCGCCAGTAGCTTGGCTGCCTGGAGCATGGAGCCGGTGGTCCGCAGGCTG
TCCACCCAGTTCACAGCTGCCAATGAGCTGGCCTGCCGAGGCTTGGACCACCTGGAGGAAAAGATCCCCGCCCTCCAGTACCCCCCTGAA
AAGATTGCTTCTGAGCTGAAGGACACCATCTCCACCCGCCTCCGCAGTGCCAGAAACAGCATCAGCGTTCCCATCGCGAGCACTTCAGAC
AAGGTCCTGGGGGCCGCTTTGGCCGGGTGCGAGCTTGCCTGGGGGGTGGCCAGAGACACTGCGGAATTTGCTGCCAACACTCGAGCTGGC
CGACTGGCTTCTGGAGGGGCCGACTTGGCCTTGGGCAGCATTGAGAAGGTGGTGGAGTACCTCCTCCCTCCAGACAAGGAAGAGTCAGCC
CCTGCTCCTGGACACCAGCAAGCCCAGAAGTCTCCCAAGGCCAAGCCAAGCCTCTTGAGCAGGGTTGGGGCTCTGACCAACACCCTCTCT
CGATACACCGTGCAGACCATGGCCCGGGCCCTGGAGCAGGGCCACACCGTGGCCATGTGGATCCCAGGCGTGGTGCCCCTGCCCCCGCAG
CCTGATGACCTCTCCATTGTGTGTTTCACAAGCGGCACGACAGGGAACCCAAAAGGTGCGATGCTCACCCATGGGAACGTGGTGGCTGAT
TTCTCAGGCTTTCTGAAAGTGACAGAGAGTCAGTGGGCTCCCACTTGTGCGGATGTGCACATTTCCTATTTGCCTTTAGCACACATGTTT
GAGCGAATGGTGCAGTCTGTCGTCTATTGCCACGGAGGGCGTGTTGGCTTCTTCCAGGGAGATATCCGCCTTCTCTCAGATGACATGAAG
GCTCTATGCCCCACCATCTTCCCTGTGGTCCCACGACTGCTGAACCGGATGTACGACAAGATCTTCAGCCAGGCAAACACACCATTAAAG
CGCTGGCTCCTGGAGTTTGCAGCAAAGCGTAAGCAAGCCGAGGTCCGGAGTGGAATCATCAGGAATGATAGTATCTGGGATGAACTCTTC
TTTAATAAGATTCAGGCCAGTCTTGGTGGGTGTGTGCGGATGATTGTTACTGGAGCAGCCCCAGCATCACCAACAGTTCTGGGATTTCTC
CGGGCAGCTCTAGGGTGCCAGGTTTATGAAGGTTATGGCCAAACTGAGTGCACAGCTGGATGTACCTTCACCACTCCTGGCGACTGGACC
TCAGGGCACGTAGGGGCGCCACTTCCCTGCAATCATATCAAGCTCGTTGATGTTGAGGAACTGAACTACTGGGCCTGCAAAGGAGAGGGA
GAGATATGTGTGAGAGGACCAAATGTGTTCAAAGGCTACTTGAAAGATCCAGACAGGACGAAGGAGGCCCTGGACAGCGATGGCTGGCTT
CACACTGGAGACATCGGAAAATGGCTGCCGGCAGGAACTCTTAAAATTATTGATCGGAAAAAGCATATATTTAAACTTGCTCAGGGAGAA
TATGTTGCACCCGAGAAGATTGAGAACATCTACATCCGGAGCCAACCTGTGGCGCAAATCTATGTCCATGGGGACAGCTTAAAGGCCTTT
TTGGTAGGCATTGTTGTGCCTGACCCTGAAGTTATGCCCTCCTGGGCCCAGAAGAGAGGAATTGAAGGAACATATGCAGATCTCTGCACA
AATAAGGATCTGAAGAAAGCCATTTTGGAAGATATGGTGAGGTTAGGAAAAGAAAGTGGACTCCATTCTTTTGAGCAGGTTAAAGCCATT
CACATCCATTCTGACATGTTCTCAGTTCAAAATGGCTTGCTGACACCAACACTAAAAGCTAAGAGACCTGAGCTGAGAGAGTACTTCAAA

>66353_66353_8_PLIN1-ACSL6_PLIN1_chr15_90212731_ENST00000430628_ACSL6_chr5_131321151_ENST00000543479_length(amino acids)=691AA_BP=257
MAVNKGLTLLDGDLPEQENVLQRVLQLPVVSGTCECFQKTYTSTKEAHPLVASVCNAYEKGVQSASSLAAWSMEPVVRRLSTQFTAANEL
ACRGLDHLEEKIPALQYPPEKIASELKDTISTRLRSARNSISVPIASTSDKVLGAALAGCELAWGVARDTAEFAANTRAGRLASGGADLA
LGSIEKVVEYLLPPDKEESAPAPGHQQAQKSPKAKPSLLSRVGALTNTLSRYTVQTMARALEQGHTVAMWIPGVVPLPPQPDDLSIVCFT
SGTTGNPKGAMLTHGNVVADFSGFLKVTESQWAPTCADVHISYLPLAHMFERMVQSVVYCHGGRVGFFQGDIRLLSDDMKALCPTIFPVV
PRLLNRMYDKIFSQANTPLKRWLLEFAAKRKQAEVRSGIIRNDSIWDELFFNKIQASLGGCVRMIVTGAAPASPTVLGFLRAALGCQVYE
GYGQTECTAGCTFTTPGDWTSGHVGAPLPCNHIKLVDVEELNYWACKGEGEICVRGPNVFKGYLKDPDRTKEALDSDGWLHTGDIGKWLP
AGTLKIIDRKKHIFKLAQGEYVAPEKIENIYIRSQPVAQIYVHGDSLKAFLVGIVVPDPEVMPSWAQKRGIEGTYADLCTNKDLKKAILE

--------------------------------------------------------------
>66353_66353_9_PLIN1-ACSL6_PLIN1_chr15_90212731_ENST00000430628_ACSL6_chr5_131321151_ENST00000544770_length(transcript)=2518nt_BP=891nt
TGGAAGCAGCATTGCCCAAGCCTCCCAGGAGTGACAGGAATTGTTTCTGCCTGAGGAGACACTCTGCAGCCTGGGCTCTGTGAGACTGAG
GTGGCGGTCAGCCGGACTTGAGGAGCGAGGATGGCAGTCAACAAAGGCCTCACCTTGCTGGATGGAGACCTCCCTGAGCAGGAGAATGTG
CTGCAGCGGGTCCTGCAGCTGCCGGTGGTGAGTGGCACCTGCGAATGCTTCCAGAAGACCTACACCAGCACTAAGGAAGCCCACCCCCTG
GTGGCCTCTGTGTGCAATGCCTATGAGAAGGGCGTGCAGAGCGCCAGTAGCTTGGCTGCCTGGAGCATGGAGCCGGTGGTCCGCAGGCTG
TCCACCCAGTTCACAGCTGCCAATGAGCTGGCCTGCCGAGGCTTGGACCACCTGGAGGAAAAGATCCCCGCCCTCCAGTACCCCCCTGAA
AAGATTGCTTCTGAGCTGAAGGACACCATCTCCACCCGCCTCCGCAGTGCCAGAAACAGCATCAGCGTTCCCATCGCGAGCACTTCAGAC
AAGGTCCTGGGGGCCGCTTTGGCCGGGTGCGAGCTTGCCTGGGGGGTGGCCAGAGACACTGCGGAATTTGCTGCCAACACTCGAGCTGGC
CGACTGGCTTCTGGAGGGGCCGACTTGGCCTTGGGCAGCATTGAGAAGGTGGTGGAGTACCTCCTCCCTCCAGACAAGGAAGAGTCAGCC
CCTGCTCCTGGACACCAGCAAGCCCAGAAGTCTCCCAAGGCCAAGCCAAGCCTCTTGAGCAGGGTTGGGGCTCTGACCAACACCCTCTCT
CGATACACCGTGCAGACCATGGCCCGGGCCCTGGAGCAGGGCCACACCGTGGCCATGTGGATCCCAGGCGTGGTGCCCCTGCCCCCGCAG
CCTGATGACCTCTCCATTGTGTGTTTCACAAGCGGCACGACAGGGAACCCAAAAGGTGCGATGCTCACCCATGGGAACGTGGTGGCTGAT
TTCTCAGGCTTTCTGAAAGTGACAGAGAAAGTGATCTTTCCGAGACAGGACGATGTGCTCATCTCCTTCCTGCCTCTGGCTCACATGTTT
GAGAGAGTAATCCAGTCTGTCGTCTATTGCCACGGAGGGCGTGTTGGCTTCTTCCAGGGAGATATCCGCCTTCTCTCAGATGACATGAAG
GCTCTATGCCCCACCATCTTCCCTGTGGTCCCACGACTGCTGAACCGGATGTACGACAAGATCTTCAGCCAGGCAAACACACCATTAAAG
CGCTGGCTCCTGGAGTTTGCAGCAAAGCGTAAGCAAGCCGAGGTCCGGAGTGGAATCATCAGGAATGATAGTATCTGGGATGAACTCTTC
TTTAATAAGATTCAGGCCAGTCTTGGTGGGTGTGTGCGGATGATTGTTACTGGAGCAGCCCCAGCATCACCAACAGTTCTGGGATTTCTC
CGGGCAGCTCTAGGGTGCCAGGTTTATGAAGGTTATGGCCAAACTGAGTGCACAGCTGGATGTACCTTCACCACTCCTGGCGACTGGACC
TCAGGGCACGTAGGGGCGCCACTTCCCTGCAATCATATCAAGCTCGTTGATGTTGAGGAACTGAACTACTGGGCCTGCAAAGGAGAGGGA
GAGATATGTGTGAGAGGACCAAATGTGTTCAAAGGCTACTTGAAAGATCCAGACAGGACGAAGGAGGCCCTGGACAGCGATGGCTGGCTT
CACACTGGAGACATCGGAAAATGGCTGCCGGCAGGAACTCTTAAAATTATTGATCGGAAAAAGCATATATTTAAACTTGCTCAGGGAGAA
TATGTTGCACCCGAGAAGATTGAGAACATCTACATCCGGAGCCAACCTGTGGCGCAAATCTATGTCCATGGGGACAGCTTAAAGGCCTTT
TTGGTAGGCATTGTTGTGCCTGACCCTGAAGTTATGCCCTCCTGGGCCCAGAAGAGAGGAATTGAAGGAACATATGCAGATCTCTGCACA
AATAAGGATCTGAAGAAAGCCATTTTGGAAGATATGGTGAGGTTAGGAAAAGAAAGTGGACTCCATTCTTTTGAGCAGGTTAAAGCCATT
CACATCCATTCTGACATGTTCTCAGTTCAAAATGGCTTGCTGACACCAACACTAAAAGCTAAGAGACCTGAGCTGAGAGAGTACTTCAAA
AAACAAATAGAAGAGCTTTACTCAATCTCCATGTGAAGTTCAAGGAAAGTTCTTCTCAGTGTAATGAACTGTCTAGCAATATTATAGTTA
TTCTTGAAAGTAATGAGTCAAAATGACACAGCTGAAAATGAATAAGCATCTGATTTTATGACTGAGCCTTTTCCTGTCCCAAGAGGTCTT
TAACAATATTTTCTCTATCATCAATGAGTATATTTTATTTTTATTATAAAAATGATATTGTGGTGGACTGCTAAAAATATCACAAATGGC

>66353_66353_9_PLIN1-ACSL6_PLIN1_chr15_90212731_ENST00000430628_ACSL6_chr5_131321151_ENST00000544770_length(amino acids)=691AA_BP=257
MAVNKGLTLLDGDLPEQENVLQRVLQLPVVSGTCECFQKTYTSTKEAHPLVASVCNAYEKGVQSASSLAAWSMEPVVRRLSTQFTAANEL
ACRGLDHLEEKIPALQYPPEKIASELKDTISTRLRSARNSISVPIASTSDKVLGAALAGCELAWGVARDTAEFAANTRAGRLASGGADLA
LGSIEKVVEYLLPPDKEESAPAPGHQQAQKSPKAKPSLLSRVGALTNTLSRYTVQTMARALEQGHTVAMWIPGVVPLPPQPDDLSIVCFT
SGTTGNPKGAMLTHGNVVADFSGFLKVTEKVIFPRQDDVLISFLPLAHMFERVIQSVVYCHGGRVGFFQGDIRLLSDDMKALCPTIFPVV
PRLLNRMYDKIFSQANTPLKRWLLEFAAKRKQAEVRSGIIRNDSIWDELFFNKIQASLGGCVRMIVTGAAPASPTVLGFLRAALGCQVYE
GYGQTECTAGCTFTTPGDWTSGHVGAPLPCNHIKLVDVEELNYWACKGEGEICVRGPNVFKGYLKDPDRTKEALDSDGWLHTGDIGKWLP
AGTLKIIDRKKHIFKLAQGEYVAPEKIENIYIRSQPVAQIYVHGDSLKAFLVGIVVPDPEVMPSWAQKRGIEGTYADLCTNKDLKKAILE

--------------------------------------------------------------

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Fusion Gene PPI Analysis for PLIN1-ACSL6


check button Go to ChiPPI (Chimeric Protein-Protein interactions) to see the chimeric PPI interaction in

ChiPPI page.


check button Protein-protein interactors with each fusion partner protein in wild-type (BIOGRID-3.4.160)
HgeneHgene's interactorsTgeneTgene's interactors


check button - Retained PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenStill interaction with


check button - Lost PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


check button - Retained PPIs, but lost function due to frame-shift fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


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Related Drugs for PLIN1-ACSL6


check button Drugs targeting genes involved in this fusion gene.
(DrugBank Version 5.1.8 2021-05-08)
PartnerGeneUniProtAccDrugBank IDDrug nameDrug activityDrug typeDrug status

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Related Diseases for PLIN1-ACSL6


check button Diseases associated with fusion partners.
(DisGeNet 4.0)
PartnerGeneDisease IDDisease name# pubmedsSource