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Center for Computational Systems Medicine
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Fusion Gene Summary

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Fusion Gene ORF analysis

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Fusion Genomic Features

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Fusion Protein Features

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Fusion Gene Sequence

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Fusion Gene PPI analysis

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Related Drugs

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Related Diseases

Fusion gene:PLXNB1-SLC26A6 (FusionGDB2 ID:66557)

Fusion Gene Summary for PLXNB1-SLC26A6

check button Fusion gene summary
Fusion gene informationFusion gene name: PLXNB1-SLC26A6
Fusion gene ID: 66557
HgeneTgene
Gene symbol

PLXNB1

SLC26A6

Gene ID

5364

65010

Gene nameplexin B1solute carrier family 26 member 6
SynonymsPLEXIN-B1|PLXN5|SEP-
Cytomap

3p21.31

3p21.31

Type of geneprotein-codingprotein-coding
Descriptionplexin-B1plexin 5semaphorin receptor SEPsolute carrier family 26 member 6anion exchange transporteranion transporter 1pendrin L1solute carrier family 26 (anion exchanger), member 6sulfate anion transporter
Modification date2020031320200329
UniProtAcc.

Q9BXS9

Ensembl transtripts involved in fusion geneENST00000296440, ENST00000358459, 
ENST00000358536, ENST00000456774, 
ENST00000448774, ENST00000465117, 
ENST00000482282, ENST00000337000, 
ENST00000358747, ENST00000383733, 
ENST00000395550, ENST00000420764, 
ENST00000455886, 
Fusion gene scores* DoF score13 X 16 X 8=16646 X 5 X 4=120
# samples 136
** MAII scorelog2(13/1664*10)=-3.67807190511264
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0		log2(6/120*10)=-1
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0
Context

PubMed: PLXNB1 [Title/Abstract] AND SLC26A6 [Title/Abstract] AND fusion [Title/Abstract]

Most frequent breakpointPLXNB1(48460986)-SLC26A6(48667144), # samples:3
Anticipated loss of major functional domain due to fusion event.PLXNB1-SLC26A6 seems lost the major protein functional domain in Tgene partner, which is a IUPHAR drug target due to the frame-shifted ORF.
* DoF score (Degree of Frequency) = # partners X # break points X # cancer types
** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10)

check button Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez
PartnerGeneGO IDGO termPubMed ID
HgenePLXNB1

GO:0007162

negative regulation of cell adhesion

15218527

HgenePLXNB1

GO:0008360

regulation of cell shape

19843518

HgenePLXNB1

GO:0051493

regulation of cytoskeleton organization

19843518

HgenePLXNB1

GO:0071526

semaphorin-plexin signaling pathway

15218527|19843518

TgeneSLC26A6

GO:0071346

cellular response to interferon-gamma

18655181


check buttonFusion gene breakpoints across PLXNB1 (5'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.
all structure

check buttonFusion gene breakpoints across SLC26A6 (3'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.
all structure

check button Fusion gene information from two resources (ChiTars 5.0 and ChimerDB 4.0)
* All genome coordinats were lifted-over on hg19.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
SourceDiseaseSampleHgeneHchrHbpHstrandTgeneTchrTbpTstrand
ChimerDB4LIHCTCGA-DD-A1EB-01APLXNB1chr3

48460986

-SLC26A6chr3

48667144

-


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Fusion Gene ORF analysis for PLXNB1-SLC26A6

check button Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
ORFHenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrand
5CDS-intronENST00000296440ENST00000482282PLXNB1chr3

48460986

-SLC26A6chr3

48667144

-
5CDS-intronENST00000358459ENST00000482282PLXNB1chr3

48460986

-SLC26A6chr3

48667144

-
5CDS-intronENST00000358536ENST00000482282PLXNB1chr3

48460986

-SLC26A6chr3

48667144

-
5CDS-intronENST00000456774ENST00000482282PLXNB1chr3

48460986

-SLC26A6chr3

48667144

-
Frame-shiftENST00000296440ENST00000337000PLXNB1chr3

48460986

-SLC26A6chr3

48667144

-
Frame-shiftENST00000296440ENST00000358747PLXNB1chr3

48460986

-SLC26A6chr3

48667144

-
Frame-shiftENST00000296440ENST00000383733PLXNB1chr3

48460986

-SLC26A6chr3

48667144

-
Frame-shiftENST00000296440ENST00000395550PLXNB1chr3

48460986

-SLC26A6chr3

48667144

-
Frame-shiftENST00000296440ENST00000420764PLXNB1chr3

48460986

-SLC26A6chr3

48667144

-
Frame-shiftENST00000296440ENST00000455886PLXNB1chr3

48460986

-SLC26A6chr3

48667144

-
Frame-shiftENST00000456774ENST00000337000PLXNB1chr3

48460986

-SLC26A6chr3

48667144

-
Frame-shiftENST00000456774ENST00000358747PLXNB1chr3

48460986

-SLC26A6chr3

48667144

-
Frame-shiftENST00000456774ENST00000383733PLXNB1chr3

48460986

-SLC26A6chr3

48667144

-
Frame-shiftENST00000456774ENST00000395550PLXNB1chr3

48460986

-SLC26A6chr3

48667144

-
Frame-shiftENST00000456774ENST00000420764PLXNB1chr3

48460986

-SLC26A6chr3

48667144

-
Frame-shiftENST00000456774ENST00000455886PLXNB1chr3

48460986

-SLC26A6chr3

48667144

-
In-frameENST00000358459ENST00000337000PLXNB1chr3

48460986

-SLC26A6chr3

48667144

-
In-frameENST00000358459ENST00000358747PLXNB1chr3

48460986

-SLC26A6chr3

48667144

-
In-frameENST00000358459ENST00000383733PLXNB1chr3

48460986

-SLC26A6chr3

48667144

-
In-frameENST00000358459ENST00000395550PLXNB1chr3

48460986

-SLC26A6chr3

48667144

-
In-frameENST00000358459ENST00000420764PLXNB1chr3

48460986

-SLC26A6chr3

48667144

-
In-frameENST00000358459ENST00000455886PLXNB1chr3

48460986

-SLC26A6chr3

48667144

-
In-frameENST00000358536ENST00000337000PLXNB1chr3

48460986

-SLC26A6chr3

48667144

-
In-frameENST00000358536ENST00000358747PLXNB1chr3

48460986

-SLC26A6chr3

48667144

-
In-frameENST00000358536ENST00000383733PLXNB1chr3

48460986

-SLC26A6chr3

48667144

-
In-frameENST00000358536ENST00000395550PLXNB1chr3

48460986

-SLC26A6chr3

48667144

-
In-frameENST00000358536ENST00000420764PLXNB1chr3

48460986

-SLC26A6chr3

48667144

-
In-frameENST00000358536ENST00000455886PLXNB1chr3

48460986

-SLC26A6chr3

48667144

-
intron-3CDSENST00000448774ENST00000337000PLXNB1chr3

48460986

-SLC26A6chr3

48667144

-
intron-3CDSENST00000448774ENST00000358747PLXNB1chr3

48460986

-SLC26A6chr3

48667144

-
intron-3CDSENST00000448774ENST00000383733PLXNB1chr3

48460986

-SLC26A6chr3

48667144

-
intron-3CDSENST00000448774ENST00000395550PLXNB1chr3

48460986

-SLC26A6chr3

48667144

-
intron-3CDSENST00000448774ENST00000420764PLXNB1chr3

48460986

-SLC26A6chr3

48667144

-
intron-3CDSENST00000448774ENST00000455886PLXNB1chr3

48460986

-SLC26A6chr3

48667144

-
intron-3CDSENST00000465117ENST00000337000PLXNB1chr3

48460986

-SLC26A6chr3

48667144

-
intron-3CDSENST00000465117ENST00000358747PLXNB1chr3

48460986

-SLC26A6chr3

48667144

-
intron-3CDSENST00000465117ENST00000383733PLXNB1chr3

48460986

-SLC26A6chr3

48667144

-
intron-3CDSENST00000465117ENST00000395550PLXNB1chr3

48460986

-SLC26A6chr3

48667144

-
intron-3CDSENST00000465117ENST00000420764PLXNB1chr3

48460986

-SLC26A6chr3

48667144

-
intron-3CDSENST00000465117ENST00000455886PLXNB1chr3

48460986

-SLC26A6chr3

48667144

-
intron-intronENST00000448774ENST00000482282PLXNB1chr3

48460986

-SLC26A6chr3

48667144

-
intron-intronENST00000465117ENST00000482282PLXNB1chr3

48460986

-SLC26A6chr3

48667144

-

check buttonORFfinder result based on the fusion transcript sequence of in-frame fusion genes.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandSeq length
(transcript)		BP loci
(transcript)		Predicted start
(transcript)		Predicted stop
(transcript)		Seq length
(amino acids)
ENST00000358459PLXNB1chr348460986-ENST00000420764SLC26A6chr348667144-344124302702564764
ENST00000358459PLXNB1chr348460986-ENST00000358747SLC26A6chr348667144-344224302702564764
ENST00000358459PLXNB1chr348460986-ENST00000395550SLC26A6chr348667144-344224302702564764
ENST00000358459PLXNB1chr348460986-ENST00000383733SLC26A6chr348667144-338524302702564764
ENST00000358459PLXNB1chr348460986-ENST00000337000SLC26A6chr348667144-343924302702564764
ENST00000358459PLXNB1chr348460986-ENST00000455886SLC26A6chr348667144-342124302702564764
ENST00000358536PLXNB1chr348460986-ENST00000420764SLC26A6chr348667144-399029792703113947
ENST00000358536PLXNB1chr348460986-ENST00000358747SLC26A6chr348667144-399129792703113947
ENST00000358536PLXNB1chr348460986-ENST00000395550SLC26A6chr348667144-399129792703113947
ENST00000358536PLXNB1chr348460986-ENST00000383733SLC26A6chr348667144-393429792703113947
ENST00000358536PLXNB1chr348460986-ENST00000337000SLC26A6chr348667144-398829792703113947
ENST00000358536PLXNB1chr348460986-ENST00000455886SLC26A6chr348667144-397029792703113947

check buttonDeepORF prediction of the coding potential based on the fusion transcript sequence of in-frame fusion genes. DeepORF is a coding potential classifier based on convolutional neural network by comparing the real Ribo-seq data. If the no-coding score < 0.5 and coding score > 0.5, then the in-frame fusion transcript is predicted as being likely translated.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandNo-coding scoreCoding score
ENST00000358459ENST00000420764PLXNB1chr348460986-SLC26A6chr348667144-0.0146148870.9853851
ENST00000358459ENST00000358747PLXNB1chr348460986-SLC26A6chr348667144-0.0149879030.98501205
ENST00000358459ENST00000395550PLXNB1chr348460986-SLC26A6chr348667144-0.0149879030.98501205
ENST00000358459ENST00000383733PLXNB1chr348460986-SLC26A6chr348667144-0.0139371860.9860628
ENST00000358459ENST00000337000PLXNB1chr348460986-SLC26A6chr348667144-0.0145321520.98546785
ENST00000358459ENST00000455886PLXNB1chr348460986-SLC26A6chr348667144-0.0155266920.9844732
ENST00000358536ENST00000420764PLXNB1chr348460986-SLC26A6chr348667144-0.0046276130.99537235
ENST00000358536ENST00000358747PLXNB1chr348460986-SLC26A6chr348667144-0.0047071420.99529284
ENST00000358536ENST00000395550PLXNB1chr348460986-SLC26A6chr348667144-0.0047071420.99529284
ENST00000358536ENST00000383733PLXNB1chr348460986-SLC26A6chr348667144-0.004628330.99537164
ENST00000358536ENST00000337000PLXNB1chr348460986-SLC26A6chr348667144-0.0046107980.9953892
ENST00000358536ENST00000455886PLXNB1chr348460986-SLC26A6chr348667144-0.004845750.99515426

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Fusion Genomic Features for PLXNB1-SLC26A6


check buttonFusionAI prediction of the potential fusion gene breakpoint based on the pre-mature RNA sequence context (+/- 5kb of individual partner genes, total 20kb length sequence). FusionAI is a fusion gene breakpoint classifier based on convolutional neural network by comparing the fusion positive and negative sequence context of ~ 20K fusion gene data. From here, we can have the relative potentency of the 20K genomic sequence how individual sequnce will be likely used as the gene fusion breakpoints.
HgeneHchrHbpHstrandTgeneTchrTbpTstrand1-pp (fusion gene breakpoint)

check buttonDistribution of 44 human genomic features loci across 20kb length fusion breakpoint regions. We integrated a total of 44 different types of human genomic feature loci information across five big categories including virus integration sites, repeats, structural variants, chromatin states, and gene expression regulation. More details are in help page.
genomic feature

check buttonDistribution of 44 human genomic features loci across 20kb length fusion breakpoint regions that are ovelapped with the top 1% feature importance score regions. More details are in help page.

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Fusion Protein Features for PLXNB1-SLC26A6


check button Four levels of functional features of fusion genes
Go to FGviewer search page for the most frequent breakpoint (https://ccsmweb.uth.edu/FGviewer/chr3:48460986/chr3:48667144)
- FGviewer provides the online visualization of the retention search of the protein functional features across DNA, RNA, protein, and pathological levels.
- How to search
1. Put your fusion gene symbol.
2. Press the tab key until there will be shown the breakpoint information filled.
4. Go down and press 'Search' tab twice.
4. Go down to have the hyperlink of the search result.
5. Click the hyperlink.
6. See the FGviewer result for your fusion gene.
FGviewer

check buttonMain function of each fusion partner protein. (from UniProt)
HgeneTgene
.SLC26A6

Q9BXS9

FUNCTION: Transcriptional activator which is required for calcium-dependent dendritic growth and branching in cortical neurons. Recruits CREB-binding protein (CREBBP) to nuclear bodies. Component of the CREST-BRG1 complex, a multiprotein complex that regulates promoter activation by orchestrating a calcium-dependent release of a repressor complex and a recruitment of an activator complex. In resting neurons, transcription of the c-FOS promoter is inhibited by BRG1-dependent recruitment of a phospho-RB1-HDAC1 repressor complex. Upon calcium influx, RB1 is dephosphorylated by calcineurin, which leads to release of the repressor complex. At the same time, there is increased recruitment of CREBBP to the promoter by a CREST-dependent mechanism, which leads to transcriptional activation. The CREST-BRG1 complex also binds to the NR2B promoter, and activity-dependent induction of NR2B expression involves a release of HDAC1 and recruitment of CREBBP (By similarity). {ECO:0000250}.FUNCTION: Apical membrane anion-exchanger with wide epithelial distribution that plays a role as a component of the pH buffering system for maintaining acid-base homeostasis. Acts as a versatile DIDS-sensitive inorganic and organic anion transporter that mediates the uptake of monovalent anions like chloride, bicarbonate, formate and hydroxyl ion and divalent anions like sulfate and oxalate. Functions in multiple exchange modes involving pairs of these anions, which include chloride-bicarbonate, chloride-oxalate, oxalate-formate, oxalate-sulfate and chloride-formate exchange. Apical membrane chloride-bicarbonate exchanger that mediates luminal chloride absorption and bicarbonate secretion by the small intestinal brush border membrane and contributes to intracellular pH regulation in the duodenal upper villous epithelium during proton-coupled peptide absorption, possibly by providing a bicarbonate import pathway. Mediates also intestinal chloride absorption and oxalate secretion, thereby preventing hyperoxaluria and calcium oxalate urolithiasis. Transepithelial oxalate secretion, chloride-formate, chloride-oxalate and chloride-bicarbonate transport activities in the duodenum are inhibited by PKC activation in a calcium-independent manner. The apical membrane chloride-bicarbonate exchanger provides also a major route for fluid and bicarbonate secretion into the proximal tubules of the kidney as well as into the proximal part of the interlobular pancreatic ductal tree, where it mediates electrogenic chloride-bicarbonate exchange with a chloride-bicarbonate stoichiometry of 1:2, and hence will dilute and alkalinize protein-rich acinar secretion. Mediates also the transcellular sulfate absorption and oxalate secretion across the apical membrane in the duodenum and the formate ion efflux at the apical brush border of cells in the proximal tubules of kidney. Plays a role in sperm capacitation by increasing intracellular pH.; FUNCTION: [Isoform 4]: Apical membrane chloride-bicarbonate exchanger. Its association with carbonic anhydrase CA2 forms a bicarbonate transport metabolon; hence maximizes the local concentration of bicarbonate at the transporter site.

check buttonRetention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at

download page


* Minus value of BPloci means that the break pointn is located before the CDS.
- In-frame and retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
HgenePLXNB1chr3:48460986chr3:48667144ENST00000296440-1138678_8299032136.0Compositional biasNote=Pro-rich
HgenePLXNB1chr3:48460986chr3:48667144ENST00000358536-1138678_8299032136.0Compositional biasNote=Pro-rich
HgenePLXNB1chr3:48460986chr3:48667144ENST00000296440-113820_4799032136.0DomainSema
HgenePLXNB1chr3:48460986chr3:48667144ENST00000358459-123920_4797201953.0DomainSema
HgenePLXNB1chr3:48460986chr3:48667144ENST00000358536-113820_4799032136.0DomainSema
HgenePLXNB1chr3:48460986chr3:48667144ENST00000456774-103720_4797201953.0DomainSema
TgeneSLC26A6chr3:48460986chr3:48667144ENST000003587471120530_742488739.0DomainSTAS
TgeneSLC26A6chr3:48460986chr3:48667144ENST000003837331220530_742509741.0DomainSTAS
TgeneSLC26A6chr3:48460986chr3:48667144ENST000003955501221530_742509760.0DomainSTAS
TgeneSLC26A6chr3:48460986chr3:48667144ENST000004207641221530_742509759.0DomainSTAS
TgeneSLC26A6chr3:48460986chr3:48667144ENST000003587471120506_759488739.0Topological domainCytoplasmic

- In-frame and not-retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
HgenePLXNB1chr3:48460986chr3:48667144ENST00000296440-11381507_15399032136.0Coiled coilOntology_term=ECO:0000255
HgenePLXNB1chr3:48460986chr3:48667144ENST00000358459-12391507_15397201953.0Coiled coilOntology_term=ECO:0000255
HgenePLXNB1chr3:48460986chr3:48667144ENST00000358536-11381507_15399032136.0Coiled coilOntology_term=ECO:0000255
HgenePLXNB1chr3:48460986chr3:48667144ENST00000456774-10371507_15397201953.0Coiled coilOntology_term=ECO:0000255
HgenePLXNB1chr3:48460986chr3:48667144ENST00000358459-1239678_8297201953.0Compositional biasNote=Pro-rich
HgenePLXNB1chr3:48460986chr3:48667144ENST00000456774-1037678_8297201953.0Compositional biasNote=Pro-rich
HgenePLXNB1chr3:48460986chr3:48667144ENST00000296440-11381070_11609032136.0DomainNote=IPT/TIG 1
HgenePLXNB1chr3:48460986chr3:48667144ENST00000296440-11381162_12499032136.0DomainNote=IPT/TIG 2
HgenePLXNB1chr3:48460986chr3:48667144ENST00000296440-11381252_13759032136.0DomainNote=IPT/TIG 3
HgenePLXNB1chr3:48460986chr3:48667144ENST00000358459-12391070_11607201953.0DomainNote=IPT/TIG 1
HgenePLXNB1chr3:48460986chr3:48667144ENST00000358459-12391162_12497201953.0DomainNote=IPT/TIG 2
HgenePLXNB1chr3:48460986chr3:48667144ENST00000358459-12391252_13757201953.0DomainNote=IPT/TIG 3
HgenePLXNB1chr3:48460986chr3:48667144ENST00000358536-11381070_11609032136.0DomainNote=IPT/TIG 1
HgenePLXNB1chr3:48460986chr3:48667144ENST00000358536-11381162_12499032136.0DomainNote=IPT/TIG 2
HgenePLXNB1chr3:48460986chr3:48667144ENST00000358536-11381252_13759032136.0DomainNote=IPT/TIG 3
HgenePLXNB1chr3:48460986chr3:48667144ENST00000456774-10371070_11607201953.0DomainNote=IPT/TIG 1
HgenePLXNB1chr3:48460986chr3:48667144ENST00000456774-10371162_12497201953.0DomainNote=IPT/TIG 2
HgenePLXNB1chr3:48460986chr3:48667144ENST00000456774-10371252_13757201953.0DomainNote=IPT/TIG 3
HgenePLXNB1chr3:48460986chr3:48667144ENST00000296440-11381512_21359032136.0Topological domainCytoplasmic
HgenePLXNB1chr3:48460986chr3:48667144ENST00000296440-113820_14909032136.0Topological domainExtracellular
HgenePLXNB1chr3:48460986chr3:48667144ENST00000358459-12391512_21357201953.0Topological domainCytoplasmic
HgenePLXNB1chr3:48460986chr3:48667144ENST00000358459-123920_14907201953.0Topological domainExtracellular
HgenePLXNB1chr3:48460986chr3:48667144ENST00000358536-11381512_21359032136.0Topological domainCytoplasmic
HgenePLXNB1chr3:48460986chr3:48667144ENST00000358536-113820_14909032136.0Topological domainExtracellular
HgenePLXNB1chr3:48460986chr3:48667144ENST00000456774-10371512_21357201953.0Topological domainCytoplasmic
HgenePLXNB1chr3:48460986chr3:48667144ENST00000456774-103720_14907201953.0Topological domainExtracellular
HgenePLXNB1chr3:48460986chr3:48667144ENST00000296440-11381491_15119032136.0TransmembraneHelical
HgenePLXNB1chr3:48460986chr3:48667144ENST00000358459-12391491_15117201953.0TransmembraneHelical
HgenePLXNB1chr3:48460986chr3:48667144ENST00000358536-11381491_15119032136.0TransmembraneHelical
HgenePLXNB1chr3:48460986chr3:48667144ENST00000456774-10371491_15117201953.0TransmembraneHelical
TgeneSLC26A6chr3:48460986chr3:48667144ENST000003587471120137_186488739.0Topological domainExtracellular
TgeneSLC26A6chr3:48460986chr3:48667144ENST0000035874711201_115488739.0Topological domainCytoplasmic
TgeneSLC26A6chr3:48460986chr3:48667144ENST000003587471120208_263488739.0Topological domainCytoplasmic
TgeneSLC26A6chr3:48460986chr3:48667144ENST000003587471120285_293488739.0Topological domainExtracellular
TgeneSLC26A6chr3:48460986chr3:48667144ENST000003587471120315_347488739.0Topological domainCytoplasmic
TgeneSLC26A6chr3:48460986chr3:48667144ENST000003587471120369_379488739.0Topological domainExtracellular
TgeneSLC26A6chr3:48460986chr3:48667144ENST000003587471120401_416488739.0Topological domainCytoplasmic
TgeneSLC26A6chr3:48460986chr3:48667144ENST000003587471120438_484488739.0Topological domainExtracellular
TgeneSLC26A6chr3:48460986chr3:48667144ENST000003837331220137_186509741.0Topological domainExtracellular
TgeneSLC26A6chr3:48460986chr3:48667144ENST0000038373312201_115509741.0Topological domainCytoplasmic
TgeneSLC26A6chr3:48460986chr3:48667144ENST000003837331220208_263509741.0Topological domainCytoplasmic
TgeneSLC26A6chr3:48460986chr3:48667144ENST000003837331220285_293509741.0Topological domainExtracellular
TgeneSLC26A6chr3:48460986chr3:48667144ENST000003837331220315_347509741.0Topological domainCytoplasmic
TgeneSLC26A6chr3:48460986chr3:48667144ENST000003837331220369_379509741.0Topological domainExtracellular
TgeneSLC26A6chr3:48460986chr3:48667144ENST000003837331220401_416509741.0Topological domainCytoplasmic
TgeneSLC26A6chr3:48460986chr3:48667144ENST000003837331220438_484509741.0Topological domainExtracellular
TgeneSLC26A6chr3:48460986chr3:48667144ENST000003837331220506_759509741.0Topological domainCytoplasmic
TgeneSLC26A6chr3:48460986chr3:48667144ENST000003955501221137_186509760.0Topological domainExtracellular
TgeneSLC26A6chr3:48460986chr3:48667144ENST0000039555012211_115509760.0Topological domainCytoplasmic
TgeneSLC26A6chr3:48460986chr3:48667144ENST000003955501221208_263509760.0Topological domainCytoplasmic
TgeneSLC26A6chr3:48460986chr3:48667144ENST000003955501221285_293509760.0Topological domainExtracellular
TgeneSLC26A6chr3:48460986chr3:48667144ENST000003955501221315_347509760.0Topological domainCytoplasmic
TgeneSLC26A6chr3:48460986chr3:48667144ENST000003955501221369_379509760.0Topological domainExtracellular
TgeneSLC26A6chr3:48460986chr3:48667144ENST000003955501221401_416509760.0Topological domainCytoplasmic
TgeneSLC26A6chr3:48460986chr3:48667144ENST000003955501221438_484509760.0Topological domainExtracellular
TgeneSLC26A6chr3:48460986chr3:48667144ENST000003955501221506_759509760.0Topological domainCytoplasmic
TgeneSLC26A6chr3:48460986chr3:48667144ENST000004207641221137_186509759.0Topological domainExtracellular
TgeneSLC26A6chr3:48460986chr3:48667144ENST0000042076412211_115509759.0Topological domainCytoplasmic
TgeneSLC26A6chr3:48460986chr3:48667144ENST000004207641221208_263509759.0Topological domainCytoplasmic
TgeneSLC26A6chr3:48460986chr3:48667144ENST000004207641221285_293509759.0Topological domainExtracellular
TgeneSLC26A6chr3:48460986chr3:48667144ENST000004207641221315_347509759.0Topological domainCytoplasmic
TgeneSLC26A6chr3:48460986chr3:48667144ENST000004207641221369_379509759.0Topological domainExtracellular
TgeneSLC26A6chr3:48460986chr3:48667144ENST000004207641221401_416509759.0Topological domainCytoplasmic
TgeneSLC26A6chr3:48460986chr3:48667144ENST000004207641221438_484509759.0Topological domainExtracellular
TgeneSLC26A6chr3:48460986chr3:48667144ENST000004207641221506_759509759.0Topological domainCytoplasmic
TgeneSLC26A6chr3:48460986chr3:48667144ENST000003587471120116_136488739.0TransmembraneHelical
TgeneSLC26A6chr3:48460986chr3:48667144ENST000003587471120187_207488739.0TransmembraneHelical
TgeneSLC26A6chr3:48460986chr3:48667144ENST000003587471120264_284488739.0TransmembraneHelical
TgeneSLC26A6chr3:48460986chr3:48667144ENST000003587471120294_314488739.0TransmembraneHelical
TgeneSLC26A6chr3:48460986chr3:48667144ENST000003587471120348_368488739.0TransmembraneHelical
TgeneSLC26A6chr3:48460986chr3:48667144ENST000003587471120380_400488739.0TransmembraneHelical
TgeneSLC26A6chr3:48460986chr3:48667144ENST000003587471120417_437488739.0TransmembraneHelical
TgeneSLC26A6chr3:48460986chr3:48667144ENST000003587471120485_505488739.0TransmembraneHelical
TgeneSLC26A6chr3:48460986chr3:48667144ENST000003837331220116_136509741.0TransmembraneHelical
TgeneSLC26A6chr3:48460986chr3:48667144ENST000003837331220187_207509741.0TransmembraneHelical
TgeneSLC26A6chr3:48460986chr3:48667144ENST000003837331220264_284509741.0TransmembraneHelical
TgeneSLC26A6chr3:48460986chr3:48667144ENST000003837331220294_314509741.0TransmembraneHelical
TgeneSLC26A6chr3:48460986chr3:48667144ENST000003837331220348_368509741.0TransmembraneHelical
TgeneSLC26A6chr3:48460986chr3:48667144ENST000003837331220380_400509741.0TransmembraneHelical
TgeneSLC26A6chr3:48460986chr3:48667144ENST000003837331220417_437509741.0TransmembraneHelical
TgeneSLC26A6chr3:48460986chr3:48667144ENST000003837331220485_505509741.0TransmembraneHelical
TgeneSLC26A6chr3:48460986chr3:48667144ENST000003955501221116_136509760.0TransmembraneHelical
TgeneSLC26A6chr3:48460986chr3:48667144ENST000003955501221187_207509760.0TransmembraneHelical
TgeneSLC26A6chr3:48460986chr3:48667144ENST000003955501221264_284509760.0TransmembraneHelical
TgeneSLC26A6chr3:48460986chr3:48667144ENST000003955501221294_314509760.0TransmembraneHelical
TgeneSLC26A6chr3:48460986chr3:48667144ENST000003955501221348_368509760.0TransmembraneHelical
TgeneSLC26A6chr3:48460986chr3:48667144ENST000003955501221380_400509760.0TransmembraneHelical
TgeneSLC26A6chr3:48460986chr3:48667144ENST000003955501221417_437509760.0TransmembraneHelical
TgeneSLC26A6chr3:48460986chr3:48667144ENST000003955501221485_505509760.0TransmembraneHelical
TgeneSLC26A6chr3:48460986chr3:48667144ENST000004207641221116_136509759.0TransmembraneHelical
TgeneSLC26A6chr3:48460986chr3:48667144ENST000004207641221187_207509759.0TransmembraneHelical
TgeneSLC26A6chr3:48460986chr3:48667144ENST000004207641221264_284509759.0TransmembraneHelical
TgeneSLC26A6chr3:48460986chr3:48667144ENST000004207641221294_314509759.0TransmembraneHelical
TgeneSLC26A6chr3:48460986chr3:48667144ENST000004207641221348_368509759.0TransmembraneHelical
TgeneSLC26A6chr3:48460986chr3:48667144ENST000004207641221380_400509759.0TransmembraneHelical
TgeneSLC26A6chr3:48460986chr3:48667144ENST000004207641221417_437509759.0TransmembraneHelical
TgeneSLC26A6chr3:48460986chr3:48667144ENST000004207641221485_505509759.0TransmembraneHelical


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Fusion Gene Sequence for PLXNB1-SLC26A6


check button For in-frame fusion transcripts, we provide the fusion transcript sequences and fusion amino acid sequences. To have fusion amino acid sequence, we ran ORFfinder and chose the longest ORF among the all predicted ones.
>66557_66557_1_PLXNB1-SLC26A6_PLXNB1_chr3_48460986_ENST00000358459_SLC26A6_chr3_48667144_ENST00000337000_length(transcript)=3439nt_BP=2430nt
GCCCGGCCGACGCGGCTTTGTCTCCTTTGTTCCCGGCGGTGGCAGCGCCGCGCGGGAGGGGCGGGCAGCGGGCGCAGTTTTCCGCCCCTC
GGTCTCCGGGTAACAGCTGCGGCTCCACCAGACCCGGGGAGAGGCCGCTGCGCGCGGAGCCCGAGCCCGGAGCGGCCGACGCCCGCCTCG
GCGCGCACATCCCGCGGGGCCCGGCCGGGTGGTGACTCCCACACGGGTCATGCTGTTGTCTCCTGATCCAGCCGGCCCTGCCAGGTGACC
ATGCCTGCTCTGGGCCCAGCTCTTCTCCAGGCTCTCTGGGCCGGGTGGGTCCTCACCCTCCAGCCCCTTCCACCAACTGCATTCACTCCC
AATGGCACGTATCTGCAGCACCTGGCAAGGGACCCCACCTCAGGCACCCTCTACCTGGGGGCTACCAACTTCCTGTTCCAGCTGAGCCCT
GGGCTGCAGCTGGAGGCCACAGTGTCCACCGGCCCTGTGCTAGACAGCAGGGACTGCCTGCCACCTGTGATGCCTGATGAGTGCCCCCAG
GCCCAGCCTACCAACAACCCGAATCAGCTGCTCCTGGTGAGCCCAGGGGCCCTGGTGGTATGCGGGAGCGTGCACCAGGGGGTCTGTGAA
CAGCGGCGCCTGGGGCAGCTCGAGCAGCTGCTGCTGCGGCCAGAGCGGCCTGGGGACACACAATATGTGGCTGCCAATGATCCTGCGGTC
AGCACGGTGGGGCTGGTAGCCCAGGGCTTGGCAGGGGAGCCCCTCCTGTTTGTGGGGCGAGGATACACCAGCAGGGGTGTGGGGGGTGGC
ATTCCACCCATCACAACCCGGGCCCTGTGGCCGCCCGACCCCCAAGCTGCCTTCTCCTATGAGGAGACAGCCAAGCTGGCAGTGGGCCGC
CTCTCCGAGTACAGCCACCACTTCGTGAGTGCCTTTGCACGTGGGGCCAGCGCCTACTTCCTGTTCCTGCGGCGGGACCTGCAGGCTCAG
TCTAGAGCTTTTCGTGCCTATGTATCTCGAGTGTGTCTCCGGGACCAGCACTACTACTCCTATGTGGAGTTGCCTCTGGCCTGCGAAGGT
GGCCGCTACGGGCTGATCCAGGCTGCAGCTGTGGCCACGTCCAGGGAGGTGGCGCATGGGGAGGTGCTCTTTGCAGCTTTCTCCTCGGCT
GCACCCCCCACTGTGGGCCGGCCCCCATCGGCGGCTGCTGGGGCATCTGGAGCCTCTGCCCTCTGTGCCTTCCCCCTGGATGAGGTGGAC
CGGCTTGCTAATCGCACGCGAGATGCCTGCTACACCCGGGAGGGTCGTGCTGAGGATGGGACCGAGGTGGCCTACATCGAGTATGATGTC
AATTCTGACTGTGCACAGCTGCCAGTGGACACCCTGGATGCTTATCCCTGTGGCTCAGACCACACGCCCAGCCCCATGGCCAGCCGGGTC
CCGCTGGAAGCCACACCAATTCTGGAGTGGCCAGGGATTCAGCTAACAGCTGTGGCAGTCACCATGGAAGATGGACACACCATCGCTTTC
CTGGGTGATAGTCAAGGGCAGCTGCACAGGGTCTACTTGGGCCCAGGGAGCGATGGCCACCCATACTCCACACAGAGCATCCAGCAGGGG
TCTGCAGTGAGCAGAGACCTCACCTTTGATGGGACCTTTGAGCACCTGTATGTCATGACCCAGAGCACACTTCTGAAGGTTCCTGTGGCT
TCCTGTGCTCAGCACCTGGACTGTGCATCTTGCCTTGCTCACAGGGACCCATACTGTGGGTGGTGCGTGCTCCTTGGCAGGTGCAGTCGC
CGTTCTGAGTGCTCGAGGGGCCAGGGCCCAGAGCAGTGGCTATGGAGCTTCCAGCCTGAGCTGGGCTGTCTGCAAGTGGCAGCCATGAGT
CCTGCCAACATCAGCCGAGAGGAGACGAGGGAGGTTTTCCTATCAGTGCCAGACCTGCCACCCCTGTGGCCAGGGGAGTCATATTCCTGC
CACTTTGGGGAACATCAGAGTCCTGCCCTGCTGACTGGTTCTGGTGTGATGTGCCCCTCCCCAGACCCTAGTGAGGCCCCAGTGCTGCCG
AGAGGAGCCGACTACGTATCCGTGAGCGTGGAGCTCAGATTTGGCGCTGTTGTGATCGCCAAAACTTCCCTCTCTTTCTATGACTGTGTG
GCGGTCACTGAACTCCGCCCATCTGCGCAGTGCCAGGCCTGTGTGAGCAGCCGCTGGGGGTGTAACTGGTGTGTCTGGCAGCACCTGTGC
ACCCACAAGGCCTCGTGTGATGCTGGGCCCATGGTTGCAAGCCATCAGAGCCCGCTTGTCTCCCCAGACCCTCCTGCAAGAGGTGATGGA
GACTCAGCAGAGCTTGAGGGCCCTCCCGCCCCCCTCATCCTCCCGTCCAGCCTCGACTACCAGTATGACACCCCCGGGCTCTGGGAGCTG
GCCCCACTACTCTGTCCTGGGGCAGGTGCCAGACACGGATATTTACAGAGATGTGGCAGAGTACTCAGAGGCCAAGGAAGTCCGGGGGGT
GAAGGTCTTCCGCTCCTCGGCCACCGTGTACTTTGCCAATGCTGAGTTCTACAGTGATGCGCTGAAGCAGAGGTGTGGTGTGGATGTCGA
CTTCCTCATCTCCCAGAAGAAGAAACTGCTCAAGAAGCAGGAGCAGCTGAAGCTGAAGCAACTGCAGAAAGAGGAGAAGCTTCGGAAACA
GGCTGCCTCCCCCAAGGGCGCCTCAGTTTCCATTAATGTCAACACCAGCCTTGAAGACATGAGGAGCAACAACGTTGAGGACTGCAAGAT
GATGGTGAGCTCAGGAGATAAGATGGAAGATGCAACAGCCAATGGTCAAGAAGACTCCAAGGCCCCAGATGGGTCCACACTGAAGGCCCT
GGGCCTGCCTCAGCCAGACTTCCACAGCCTCATCCTGGACCTGGGTGCCCTCTCCTTTGTGGACACTGTGTGCCTCAAGAGCCTGAAGAA
TATTTTCCATGACTTCCGGGAGATTGAGGTGGAGGTGTACATGGCGGCCTGCCACAGCCCTGTGGTCAGCCAGCTTGAGGCTGGGCACTT
CTTCGATGCATCCATCACCAAGAAGCATCTCTTTGCCTCTGTCCATGATGCTGTCACCTTTGCCCTCCAACACCCGAGGCCTGTCCCCGA
CAGCCCTGTTTCGGTCACCAGACTCTGAACATGCTACATCCTGCCCAAGACTGCACCTCTGGAGGTGCAGGGCACCCTTGAGAAGCCCCT
CACCCCTAGGCCGCCTCCAGGTGCTACCCAGGAGTCCCCTCCATGTACACACACACAACTCAGGGAAGGAGGTCCTGGGACTCCAAGTTC
AGCGCTCCAGGTCTGGGACAGGGCCTGCATGCAGTCAGGCTGGCAGTGGCGCGGTACAGGGAGGGAACTGGTGCATATTTTAGCCTCAGG

>66557_66557_1_PLXNB1-SLC26A6_PLXNB1_chr3_48460986_ENST00000358459_SLC26A6_chr3_48667144_ENST00000337000_length(amino acids)=764AA_BP=720
MPALGPALLQALWAGWVLTLQPLPPTAFTPNGTYLQHLARDPTSGTLYLGATNFLFQLSPGLQLEATVSTGPVLDSRDCLPPVMPDECPQ
AQPTNNPNQLLLVSPGALVVCGSVHQGVCEQRRLGQLEQLLLRPERPGDTQYVAANDPAVSTVGLVAQGLAGEPLLFVGRGYTSRGVGGG
IPPITTRALWPPDPQAAFSYEETAKLAVGRLSEYSHHFVSAFARGASAYFLFLRRDLQAQSRAFRAYVSRVCLRDQHYYSYVELPLACEG
GRYGLIQAAAVATSREVAHGEVLFAAFSSAAPPTVGRPPSAAAGASGASALCAFPLDEVDRLANRTRDACYTREGRAEDGTEVAYIEYDV
NSDCAQLPVDTLDAYPCGSDHTPSPMASRVPLEATPILEWPGIQLTAVAVTMEDGHTIAFLGDSQGQLHRVYLGPGSDGHPYSTQSIQQG
SAVSRDLTFDGTFEHLYVMTQSTLLKVPVASCAQHLDCASCLAHRDPYCGWCVLLGRCSRRSECSRGQGPEQWLWSFQPELGCLQVAAMS
PANISREETREVFLSVPDLPPLWPGESYSCHFGEHQSPALLTGSGVMCPSPDPSEAPVLPRGADYVSVSVELRFGAVVIAKTSLSFYDCV
AVTELRPSAQCQACVSSRWGCNWCVWQHLCTHKASCDAGPMVASHQSPLVSPDPPARGDGDSAELEGPPAPLILPSSLDYQYDTPGLWEL

--------------------------------------------------------------
>66557_66557_2_PLXNB1-SLC26A6_PLXNB1_chr3_48460986_ENST00000358459_SLC26A6_chr3_48667144_ENST00000358747_length(transcript)=3442nt_BP=2430nt
GCCCGGCCGACGCGGCTTTGTCTCCTTTGTTCCCGGCGGTGGCAGCGCCGCGCGGGAGGGGCGGGCAGCGGGCGCAGTTTTCCGCCCCTC
GGTCTCCGGGTAACAGCTGCGGCTCCACCAGACCCGGGGAGAGGCCGCTGCGCGCGGAGCCCGAGCCCGGAGCGGCCGACGCCCGCCTCG
GCGCGCACATCCCGCGGGGCCCGGCCGGGTGGTGACTCCCACACGGGTCATGCTGTTGTCTCCTGATCCAGCCGGCCCTGCCAGGTGACC
ATGCCTGCTCTGGGCCCAGCTCTTCTCCAGGCTCTCTGGGCCGGGTGGGTCCTCACCCTCCAGCCCCTTCCACCAACTGCATTCACTCCC
AATGGCACGTATCTGCAGCACCTGGCAAGGGACCCCACCTCAGGCACCCTCTACCTGGGGGCTACCAACTTCCTGTTCCAGCTGAGCCCT
GGGCTGCAGCTGGAGGCCACAGTGTCCACCGGCCCTGTGCTAGACAGCAGGGACTGCCTGCCACCTGTGATGCCTGATGAGTGCCCCCAG
GCCCAGCCTACCAACAACCCGAATCAGCTGCTCCTGGTGAGCCCAGGGGCCCTGGTGGTATGCGGGAGCGTGCACCAGGGGGTCTGTGAA
CAGCGGCGCCTGGGGCAGCTCGAGCAGCTGCTGCTGCGGCCAGAGCGGCCTGGGGACACACAATATGTGGCTGCCAATGATCCTGCGGTC
AGCACGGTGGGGCTGGTAGCCCAGGGCTTGGCAGGGGAGCCCCTCCTGTTTGTGGGGCGAGGATACACCAGCAGGGGTGTGGGGGGTGGC
ATTCCACCCATCACAACCCGGGCCCTGTGGCCGCCCGACCCCCAAGCTGCCTTCTCCTATGAGGAGACAGCCAAGCTGGCAGTGGGCCGC
CTCTCCGAGTACAGCCACCACTTCGTGAGTGCCTTTGCACGTGGGGCCAGCGCCTACTTCCTGTTCCTGCGGCGGGACCTGCAGGCTCAG
TCTAGAGCTTTTCGTGCCTATGTATCTCGAGTGTGTCTCCGGGACCAGCACTACTACTCCTATGTGGAGTTGCCTCTGGCCTGCGAAGGT
GGCCGCTACGGGCTGATCCAGGCTGCAGCTGTGGCCACGTCCAGGGAGGTGGCGCATGGGGAGGTGCTCTTTGCAGCTTTCTCCTCGGCT
GCACCCCCCACTGTGGGCCGGCCCCCATCGGCGGCTGCTGGGGCATCTGGAGCCTCTGCCCTCTGTGCCTTCCCCCTGGATGAGGTGGAC
CGGCTTGCTAATCGCACGCGAGATGCCTGCTACACCCGGGAGGGTCGTGCTGAGGATGGGACCGAGGTGGCCTACATCGAGTATGATGTC
AATTCTGACTGTGCACAGCTGCCAGTGGACACCCTGGATGCTTATCCCTGTGGCTCAGACCACACGCCCAGCCCCATGGCCAGCCGGGTC
CCGCTGGAAGCCACACCAATTCTGGAGTGGCCAGGGATTCAGCTAACAGCTGTGGCAGTCACCATGGAAGATGGACACACCATCGCTTTC
CTGGGTGATAGTCAAGGGCAGCTGCACAGGGTCTACTTGGGCCCAGGGAGCGATGGCCACCCATACTCCACACAGAGCATCCAGCAGGGG
TCTGCAGTGAGCAGAGACCTCACCTTTGATGGGACCTTTGAGCACCTGTATGTCATGACCCAGAGCACACTTCTGAAGGTTCCTGTGGCT
TCCTGTGCTCAGCACCTGGACTGTGCATCTTGCCTTGCTCACAGGGACCCATACTGTGGGTGGTGCGTGCTCCTTGGCAGGTGCAGTCGC
CGTTCTGAGTGCTCGAGGGGCCAGGGCCCAGAGCAGTGGCTATGGAGCTTCCAGCCTGAGCTGGGCTGTCTGCAAGTGGCAGCCATGAGT
CCTGCCAACATCAGCCGAGAGGAGACGAGGGAGGTTTTCCTATCAGTGCCAGACCTGCCACCCCTGTGGCCAGGGGAGTCATATTCCTGC
CACTTTGGGGAACATCAGAGTCCTGCCCTGCTGACTGGTTCTGGTGTGATGTGCCCCTCCCCAGACCCTAGTGAGGCCCCAGTGCTGCCG
AGAGGAGCCGACTACGTATCCGTGAGCGTGGAGCTCAGATTTGGCGCTGTTGTGATCGCCAAAACTTCCCTCTCTTTCTATGACTGTGTG
GCGGTCACTGAACTCCGCCCATCTGCGCAGTGCCAGGCCTGTGTGAGCAGCCGCTGGGGGTGTAACTGGTGTGTCTGGCAGCACCTGTGC
ACCCACAAGGCCTCGTGTGATGCTGGGCCCATGGTTGCAAGCCATCAGAGCCCGCTTGTCTCCCCAGACCCTCCTGCAAGAGGTGATGGA
GACTCAGCAGAGCTTGAGGGCCCTCCCGCCCCCCTCATCCTCCCGTCCAGCCTCGACTACCAGTATGACACCCCCGGGCTCTGGGAGCTG
GCCCCACTACTCTGTCCTGGGGCAGGTGCCAGACACGGATATTTACAGAGATGTGGCAGAGTACTCAGAGGCCAAGGAAGTCCGGGGGGT
GAAGGTCTTCCGCTCCTCGGCCACCGTGTACTTTGCCAATGCTGAGTTCTACAGTGATGCGCTGAAGCAGAGGTGTGGTGTGGATGTCGA
CTTCCTCATCTCCCAGAAGAAGAAACTGCTCAAGAAGCAGGAGCAGCTGAAGCTGAAGCAACTGCAGAAAGAGGAGAAGCTTCGGAAACA
GGCTGCCTCCCCCAAGGGCGCCTCAGTTTCCATTAATGTCAACACCAGCCTTGAAGACATGAGGAGCAACAACGTTGAGGACTGCAAGAT
GATGCAGGTGAGCTCAGGAGATAAGATGGAAGATGCAACAGCCAATGGTCAAGAAGACTCCAAGGCCCCAGATGGGTCCACACTGAAGGC
CCTGGGCCTGCCTCAGCCAGACTTCCACAGCCTCATCCTGGACCTGGGTGCCCTCTCCTTTGTGGACACTGTGTGCCTCAAGAGCCTGAA
GAATATTTTCCATGACTTCCGGGAGATTGAGGTGGAGGTGTACATGGCGGCCTGCCACAGCCCTGTGGTCAGCCAGCTTGAGGCTGGGCA
CTTCTTCGATGCATCCATCACCAAGAAGCATCTCTTTGCCTCTGTCCATGATGCTGTCACCTTTGCCCTCCAACACCCGAGGCCTGTCCC
CGACAGCCCTGTTTCGGTCACCAGACTCTGAACATGCTACATCCTGCCCAAGACTGCACCTCTGGAGGTGCAGGGCACCCTTGAGAAGCC
CCTCACCCCTAGGCCGCCTCCAGGTGCTACCCAGGAGTCCCCTCCATGTACACACACACAACTCAGGGAAGGAGGTCCTGGGACTCCAAG
TTCAGCGCTCCAGGTCTGGGACAGGGCCTGCATGCAGTCAGGCTGGCAGTGGCGCGGTACAGGGAGGGAACTGGTGCATATTTTAGCCTC

>66557_66557_2_PLXNB1-SLC26A6_PLXNB1_chr3_48460986_ENST00000358459_SLC26A6_chr3_48667144_ENST00000358747_length(amino acids)=764AA_BP=720
MPALGPALLQALWAGWVLTLQPLPPTAFTPNGTYLQHLARDPTSGTLYLGATNFLFQLSPGLQLEATVSTGPVLDSRDCLPPVMPDECPQ
AQPTNNPNQLLLVSPGALVVCGSVHQGVCEQRRLGQLEQLLLRPERPGDTQYVAANDPAVSTVGLVAQGLAGEPLLFVGRGYTSRGVGGG
IPPITTRALWPPDPQAAFSYEETAKLAVGRLSEYSHHFVSAFARGASAYFLFLRRDLQAQSRAFRAYVSRVCLRDQHYYSYVELPLACEG
GRYGLIQAAAVATSREVAHGEVLFAAFSSAAPPTVGRPPSAAAGASGASALCAFPLDEVDRLANRTRDACYTREGRAEDGTEVAYIEYDV
NSDCAQLPVDTLDAYPCGSDHTPSPMASRVPLEATPILEWPGIQLTAVAVTMEDGHTIAFLGDSQGQLHRVYLGPGSDGHPYSTQSIQQG
SAVSRDLTFDGTFEHLYVMTQSTLLKVPVASCAQHLDCASCLAHRDPYCGWCVLLGRCSRRSECSRGQGPEQWLWSFQPELGCLQVAAMS
PANISREETREVFLSVPDLPPLWPGESYSCHFGEHQSPALLTGSGVMCPSPDPSEAPVLPRGADYVSVSVELRFGAVVIAKTSLSFYDCV
AVTELRPSAQCQACVSSRWGCNWCVWQHLCTHKASCDAGPMVASHQSPLVSPDPPARGDGDSAELEGPPAPLILPSSLDYQYDTPGLWEL

--------------------------------------------------------------
>66557_66557_3_PLXNB1-SLC26A6_PLXNB1_chr3_48460986_ENST00000358459_SLC26A6_chr3_48667144_ENST00000383733_length(transcript)=3385nt_BP=2430nt
GCCCGGCCGACGCGGCTTTGTCTCCTTTGTTCCCGGCGGTGGCAGCGCCGCGCGGGAGGGGCGGGCAGCGGGCGCAGTTTTCCGCCCCTC
GGTCTCCGGGTAACAGCTGCGGCTCCACCAGACCCGGGGAGAGGCCGCTGCGCGCGGAGCCCGAGCCCGGAGCGGCCGACGCCCGCCTCG
GCGCGCACATCCCGCGGGGCCCGGCCGGGTGGTGACTCCCACACGGGTCATGCTGTTGTCTCCTGATCCAGCCGGCCCTGCCAGGTGACC
ATGCCTGCTCTGGGCCCAGCTCTTCTCCAGGCTCTCTGGGCCGGGTGGGTCCTCACCCTCCAGCCCCTTCCACCAACTGCATTCACTCCC
AATGGCACGTATCTGCAGCACCTGGCAAGGGACCCCACCTCAGGCACCCTCTACCTGGGGGCTACCAACTTCCTGTTCCAGCTGAGCCCT
GGGCTGCAGCTGGAGGCCACAGTGTCCACCGGCCCTGTGCTAGACAGCAGGGACTGCCTGCCACCTGTGATGCCTGATGAGTGCCCCCAG
GCCCAGCCTACCAACAACCCGAATCAGCTGCTCCTGGTGAGCCCAGGGGCCCTGGTGGTATGCGGGAGCGTGCACCAGGGGGTCTGTGAA
CAGCGGCGCCTGGGGCAGCTCGAGCAGCTGCTGCTGCGGCCAGAGCGGCCTGGGGACACACAATATGTGGCTGCCAATGATCCTGCGGTC
AGCACGGTGGGGCTGGTAGCCCAGGGCTTGGCAGGGGAGCCCCTCCTGTTTGTGGGGCGAGGATACACCAGCAGGGGTGTGGGGGGTGGC
ATTCCACCCATCACAACCCGGGCCCTGTGGCCGCCCGACCCCCAAGCTGCCTTCTCCTATGAGGAGACAGCCAAGCTGGCAGTGGGCCGC
CTCTCCGAGTACAGCCACCACTTCGTGAGTGCCTTTGCACGTGGGGCCAGCGCCTACTTCCTGTTCCTGCGGCGGGACCTGCAGGCTCAG
TCTAGAGCTTTTCGTGCCTATGTATCTCGAGTGTGTCTCCGGGACCAGCACTACTACTCCTATGTGGAGTTGCCTCTGGCCTGCGAAGGT
GGCCGCTACGGGCTGATCCAGGCTGCAGCTGTGGCCACGTCCAGGGAGGTGGCGCATGGGGAGGTGCTCTTTGCAGCTTTCTCCTCGGCT
GCACCCCCCACTGTGGGCCGGCCCCCATCGGCGGCTGCTGGGGCATCTGGAGCCTCTGCCCTCTGTGCCTTCCCCCTGGATGAGGTGGAC
CGGCTTGCTAATCGCACGCGAGATGCCTGCTACACCCGGGAGGGTCGTGCTGAGGATGGGACCGAGGTGGCCTACATCGAGTATGATGTC
AATTCTGACTGTGCACAGCTGCCAGTGGACACCCTGGATGCTTATCCCTGTGGCTCAGACCACACGCCCAGCCCCATGGCCAGCCGGGTC
CCGCTGGAAGCCACACCAATTCTGGAGTGGCCAGGGATTCAGCTAACAGCTGTGGCAGTCACCATGGAAGATGGACACACCATCGCTTTC
CTGGGTGATAGTCAAGGGCAGCTGCACAGGGTCTACTTGGGCCCAGGGAGCGATGGCCACCCATACTCCACACAGAGCATCCAGCAGGGG
TCTGCAGTGAGCAGAGACCTCACCTTTGATGGGACCTTTGAGCACCTGTATGTCATGACCCAGAGCACACTTCTGAAGGTTCCTGTGGCT
TCCTGTGCTCAGCACCTGGACTGTGCATCTTGCCTTGCTCACAGGGACCCATACTGTGGGTGGTGCGTGCTCCTTGGCAGGTGCAGTCGC
CGTTCTGAGTGCTCGAGGGGCCAGGGCCCAGAGCAGTGGCTATGGAGCTTCCAGCCTGAGCTGGGCTGTCTGCAAGTGGCAGCCATGAGT
CCTGCCAACATCAGCCGAGAGGAGACGAGGGAGGTTTTCCTATCAGTGCCAGACCTGCCACCCCTGTGGCCAGGGGAGTCATATTCCTGC
CACTTTGGGGAACATCAGAGTCCTGCCCTGCTGACTGGTTCTGGTGTGATGTGCCCCTCCCCAGACCCTAGTGAGGCCCCAGTGCTGCCG
AGAGGAGCCGACTACGTATCCGTGAGCGTGGAGCTCAGATTTGGCGCTGTTGTGATCGCCAAAACTTCCCTCTCTTTCTATGACTGTGTG
GCGGTCACTGAACTCCGCCCATCTGCGCAGTGCCAGGCCTGTGTGAGCAGCCGCTGGGGGTGTAACTGGTGTGTCTGGCAGCACCTGTGC
ACCCACAAGGCCTCGTGTGATGCTGGGCCCATGGTTGCAAGCCATCAGAGCCCGCTTGTCTCCCCAGACCCTCCTGCAAGAGGTGATGGA
GACTCAGCAGAGCTTGAGGGCCCTCCCGCCCCCCTCATCCTCCCGTCCAGCCTCGACTACCAGTATGACACCCCCGGGCTCTGGGAGCTG
GCCCCACTACTCTGTCCTGGGGCAGGTGCCAGACACGGATATTTACAGAGATGTGGCAGAGTACTCAGAGGCCAAGGAAGTCCGGGGGGT
GAAGGTCTTCCGCTCCTCGGCCACCGTGTACTTTGCCAATGCTGAGTTCTACAGTGATGCGCTGAAGCAGAGGTGTGGTGTGGATGTCGA
CTTCCTCATCTCCCAGAAGAAGAAACTGCTCAAGAAGCAGGAGCAGCTGAAGCTGAAGCAACTGCAGAAAGAGGAGAAGCTTCGGAAACA
GGCAGGGCCCCTTTTGTCTGCATGTCTGGCTCCCCAGCAGGTGAGCTCAGGAGATAAGATGGAAGATGCAACAGCCAATGGTCAAGAAGA
CTCCAAGGCCCCAGATGGGTCCACACTGAAGGCCCTGGGCCTGCCTCAGCCAGACTTCCACAGCCTCATCCTGGACCTGGGTGCCCTCTC
CTTTGTGGACACTGTGTGCCTCAAGAGCCTGAAGAATATTTTCCATGACTTCCGGGAGATTGAGGTGGAGGTGTACATGGCGGCCTGCCA
CAGCCCTGTGGTCAGCCAGCTTGAGGCTGGGCACTTCTTCGATGCATCCATCACCAAGAAGCATCTCTTTGCCTCTGTCCATGATGCTGT
CACCTTTGCCCTCCAACACCCGAGGCCTGTCCCCGACAGCCCTGTTTCGGTCACCAGACTCTGAACATGCTACATCCTGCCCAAGACTGC
ACCTCTGGAGGTGCAGGGCACCCTTGAGAAGCCCCTCACCCCTAGGCCGCCTCCAGGTGCTACCCAGGAGTCCCCTCCATGTACACACAC
ACAACTCAGGGAAGGAGGTCCTGGGACTCCAAGTTCAGCGCTCCAGGTCTGGGACAGGGCCTGCATGCAGTCAGGCTGGCAGTGGCGCGG

>66557_66557_3_PLXNB1-SLC26A6_PLXNB1_chr3_48460986_ENST00000358459_SLC26A6_chr3_48667144_ENST00000383733_length(amino acids)=764AA_BP=720
MPALGPALLQALWAGWVLTLQPLPPTAFTPNGTYLQHLARDPTSGTLYLGATNFLFQLSPGLQLEATVSTGPVLDSRDCLPPVMPDECPQ
AQPTNNPNQLLLVSPGALVVCGSVHQGVCEQRRLGQLEQLLLRPERPGDTQYVAANDPAVSTVGLVAQGLAGEPLLFVGRGYTSRGVGGG
IPPITTRALWPPDPQAAFSYEETAKLAVGRLSEYSHHFVSAFARGASAYFLFLRRDLQAQSRAFRAYVSRVCLRDQHYYSYVELPLACEG
GRYGLIQAAAVATSREVAHGEVLFAAFSSAAPPTVGRPPSAAAGASGASALCAFPLDEVDRLANRTRDACYTREGRAEDGTEVAYIEYDV
NSDCAQLPVDTLDAYPCGSDHTPSPMASRVPLEATPILEWPGIQLTAVAVTMEDGHTIAFLGDSQGQLHRVYLGPGSDGHPYSTQSIQQG
SAVSRDLTFDGTFEHLYVMTQSTLLKVPVASCAQHLDCASCLAHRDPYCGWCVLLGRCSRRSECSRGQGPEQWLWSFQPELGCLQVAAMS
PANISREETREVFLSVPDLPPLWPGESYSCHFGEHQSPALLTGSGVMCPSPDPSEAPVLPRGADYVSVSVELRFGAVVIAKTSLSFYDCV
AVTELRPSAQCQACVSSRWGCNWCVWQHLCTHKASCDAGPMVASHQSPLVSPDPPARGDGDSAELEGPPAPLILPSSLDYQYDTPGLWEL

--------------------------------------------------------------
>66557_66557_4_PLXNB1-SLC26A6_PLXNB1_chr3_48460986_ENST00000358459_SLC26A6_chr3_48667144_ENST00000395550_length(transcript)=3442nt_BP=2430nt
GCCCGGCCGACGCGGCTTTGTCTCCTTTGTTCCCGGCGGTGGCAGCGCCGCGCGGGAGGGGCGGGCAGCGGGCGCAGTTTTCCGCCCCTC
GGTCTCCGGGTAACAGCTGCGGCTCCACCAGACCCGGGGAGAGGCCGCTGCGCGCGGAGCCCGAGCCCGGAGCGGCCGACGCCCGCCTCG
GCGCGCACATCCCGCGGGGCCCGGCCGGGTGGTGACTCCCACACGGGTCATGCTGTTGTCTCCTGATCCAGCCGGCCCTGCCAGGTGACC
ATGCCTGCTCTGGGCCCAGCTCTTCTCCAGGCTCTCTGGGCCGGGTGGGTCCTCACCCTCCAGCCCCTTCCACCAACTGCATTCACTCCC
AATGGCACGTATCTGCAGCACCTGGCAAGGGACCCCACCTCAGGCACCCTCTACCTGGGGGCTACCAACTTCCTGTTCCAGCTGAGCCCT
GGGCTGCAGCTGGAGGCCACAGTGTCCACCGGCCCTGTGCTAGACAGCAGGGACTGCCTGCCACCTGTGATGCCTGATGAGTGCCCCCAG
GCCCAGCCTACCAACAACCCGAATCAGCTGCTCCTGGTGAGCCCAGGGGCCCTGGTGGTATGCGGGAGCGTGCACCAGGGGGTCTGTGAA
CAGCGGCGCCTGGGGCAGCTCGAGCAGCTGCTGCTGCGGCCAGAGCGGCCTGGGGACACACAATATGTGGCTGCCAATGATCCTGCGGTC
AGCACGGTGGGGCTGGTAGCCCAGGGCTTGGCAGGGGAGCCCCTCCTGTTTGTGGGGCGAGGATACACCAGCAGGGGTGTGGGGGGTGGC
ATTCCACCCATCACAACCCGGGCCCTGTGGCCGCCCGACCCCCAAGCTGCCTTCTCCTATGAGGAGACAGCCAAGCTGGCAGTGGGCCGC
CTCTCCGAGTACAGCCACCACTTCGTGAGTGCCTTTGCACGTGGGGCCAGCGCCTACTTCCTGTTCCTGCGGCGGGACCTGCAGGCTCAG
TCTAGAGCTTTTCGTGCCTATGTATCTCGAGTGTGTCTCCGGGACCAGCACTACTACTCCTATGTGGAGTTGCCTCTGGCCTGCGAAGGT
GGCCGCTACGGGCTGATCCAGGCTGCAGCTGTGGCCACGTCCAGGGAGGTGGCGCATGGGGAGGTGCTCTTTGCAGCTTTCTCCTCGGCT
GCACCCCCCACTGTGGGCCGGCCCCCATCGGCGGCTGCTGGGGCATCTGGAGCCTCTGCCCTCTGTGCCTTCCCCCTGGATGAGGTGGAC
CGGCTTGCTAATCGCACGCGAGATGCCTGCTACACCCGGGAGGGTCGTGCTGAGGATGGGACCGAGGTGGCCTACATCGAGTATGATGTC
AATTCTGACTGTGCACAGCTGCCAGTGGACACCCTGGATGCTTATCCCTGTGGCTCAGACCACACGCCCAGCCCCATGGCCAGCCGGGTC
CCGCTGGAAGCCACACCAATTCTGGAGTGGCCAGGGATTCAGCTAACAGCTGTGGCAGTCACCATGGAAGATGGACACACCATCGCTTTC
CTGGGTGATAGTCAAGGGCAGCTGCACAGGGTCTACTTGGGCCCAGGGAGCGATGGCCACCCATACTCCACACAGAGCATCCAGCAGGGG
TCTGCAGTGAGCAGAGACCTCACCTTTGATGGGACCTTTGAGCACCTGTATGTCATGACCCAGAGCACACTTCTGAAGGTTCCTGTGGCT
TCCTGTGCTCAGCACCTGGACTGTGCATCTTGCCTTGCTCACAGGGACCCATACTGTGGGTGGTGCGTGCTCCTTGGCAGGTGCAGTCGC
CGTTCTGAGTGCTCGAGGGGCCAGGGCCCAGAGCAGTGGCTATGGAGCTTCCAGCCTGAGCTGGGCTGTCTGCAAGTGGCAGCCATGAGT
CCTGCCAACATCAGCCGAGAGGAGACGAGGGAGGTTTTCCTATCAGTGCCAGACCTGCCACCCCTGTGGCCAGGGGAGTCATATTCCTGC
CACTTTGGGGAACATCAGAGTCCTGCCCTGCTGACTGGTTCTGGTGTGATGTGCCCCTCCCCAGACCCTAGTGAGGCCCCAGTGCTGCCG
AGAGGAGCCGACTACGTATCCGTGAGCGTGGAGCTCAGATTTGGCGCTGTTGTGATCGCCAAAACTTCCCTCTCTTTCTATGACTGTGTG
GCGGTCACTGAACTCCGCCCATCTGCGCAGTGCCAGGCCTGTGTGAGCAGCCGCTGGGGGTGTAACTGGTGTGTCTGGCAGCACCTGTGC
ACCCACAAGGCCTCGTGTGATGCTGGGCCCATGGTTGCAAGCCATCAGAGCCCGCTTGTCTCCCCAGACCCTCCTGCAAGAGGTGATGGA
GACTCAGCAGAGCTTGAGGGCCCTCCCGCCCCCCTCATCCTCCCGTCCAGCCTCGACTACCAGTATGACACCCCCGGGCTCTGGGAGCTG
GCCCCACTACTCTGTCCTGGGGCAGGTGCCAGACACGGATATTTACAGAGATGTGGCAGAGTACTCAGAGGCCAAGGAAGTCCGGGGGGT
GAAGGTCTTCCGCTCCTCGGCCACCGTGTACTTTGCCAATGCTGAGTTCTACAGTGATGCGCTGAAGCAGAGGTGTGGTGTGGATGTCGA
CTTCCTCATCTCCCAGAAGAAGAAACTGCTCAAGAAGCAGGAGCAGCTGAAGCTGAAGCAACTGCAGAAAGAGGAGAAGCTTCGGAAACA
GGCTGCCTCCCCCAAGGGCGCCTCAGTTTCCATTAATGTCAACACCAGCCTTGAAGACATGAGGAGCAACAACGTTGAGGACTGCAAGAT
GATGCAGGTGAGCTCAGGAGATAAGATGGAAGATGCAACAGCCAATGGTCAAGAAGACTCCAAGGCCCCAGATGGGTCCACACTGAAGGC
CCTGGGCCTGCCTCAGCCAGACTTCCACAGCCTCATCCTGGACCTGGGTGCCCTCTCCTTTGTGGACACTGTGTGCCTCAAGAGCCTGAA
GAATATTTTCCATGACTTCCGGGAGATTGAGGTGGAGGTGTACATGGCGGCCTGCCACAGCCCTGTGGTCAGCCAGCTTGAGGCTGGGCA
CTTCTTCGATGCATCCATCACCAAGAAGCATCTCTTTGCCTCTGTCCATGATGCTGTCACCTTTGCCCTCCAACACCCGAGGCCTGTCCC
CGACAGCCCTGTTTCGGTCACCAGACTCTGAACATGCTACATCCTGCCCAAGACTGCACCTCTGGAGGTGCAGGGCACCCTTGAGAAGCC
CCTCACCCCTAGGCCGCCTCCAGGTGCTACCCAGGAGTCCCCTCCATGTACACACACACAACTCAGGGAAGGAGGTCCTGGGACTCCAAG
TTCAGCGCTCCAGGTCTGGGACAGGGCCTGCATGCAGTCAGGCTGGCAGTGGCGCGGTACAGGGAGGGAACTGGTGCATATTTTAGCCTC

>66557_66557_4_PLXNB1-SLC26A6_PLXNB1_chr3_48460986_ENST00000358459_SLC26A6_chr3_48667144_ENST00000395550_length(amino acids)=764AA_BP=720
MPALGPALLQALWAGWVLTLQPLPPTAFTPNGTYLQHLARDPTSGTLYLGATNFLFQLSPGLQLEATVSTGPVLDSRDCLPPVMPDECPQ
AQPTNNPNQLLLVSPGALVVCGSVHQGVCEQRRLGQLEQLLLRPERPGDTQYVAANDPAVSTVGLVAQGLAGEPLLFVGRGYTSRGVGGG
IPPITTRALWPPDPQAAFSYEETAKLAVGRLSEYSHHFVSAFARGASAYFLFLRRDLQAQSRAFRAYVSRVCLRDQHYYSYVELPLACEG
GRYGLIQAAAVATSREVAHGEVLFAAFSSAAPPTVGRPPSAAAGASGASALCAFPLDEVDRLANRTRDACYTREGRAEDGTEVAYIEYDV
NSDCAQLPVDTLDAYPCGSDHTPSPMASRVPLEATPILEWPGIQLTAVAVTMEDGHTIAFLGDSQGQLHRVYLGPGSDGHPYSTQSIQQG
SAVSRDLTFDGTFEHLYVMTQSTLLKVPVASCAQHLDCASCLAHRDPYCGWCVLLGRCSRRSECSRGQGPEQWLWSFQPELGCLQVAAMS
PANISREETREVFLSVPDLPPLWPGESYSCHFGEHQSPALLTGSGVMCPSPDPSEAPVLPRGADYVSVSVELRFGAVVIAKTSLSFYDCV
AVTELRPSAQCQACVSSRWGCNWCVWQHLCTHKASCDAGPMVASHQSPLVSPDPPARGDGDSAELEGPPAPLILPSSLDYQYDTPGLWEL

--------------------------------------------------------------
>66557_66557_5_PLXNB1-SLC26A6_PLXNB1_chr3_48460986_ENST00000358459_SLC26A6_chr3_48667144_ENST00000420764_length(transcript)=3441nt_BP=2430nt
GCCCGGCCGACGCGGCTTTGTCTCCTTTGTTCCCGGCGGTGGCAGCGCCGCGCGGGAGGGGCGGGCAGCGGGCGCAGTTTTCCGCCCCTC
GGTCTCCGGGTAACAGCTGCGGCTCCACCAGACCCGGGGAGAGGCCGCTGCGCGCGGAGCCCGAGCCCGGAGCGGCCGACGCCCGCCTCG
GCGCGCACATCCCGCGGGGCCCGGCCGGGTGGTGACTCCCACACGGGTCATGCTGTTGTCTCCTGATCCAGCCGGCCCTGCCAGGTGACC
ATGCCTGCTCTGGGCCCAGCTCTTCTCCAGGCTCTCTGGGCCGGGTGGGTCCTCACCCTCCAGCCCCTTCCACCAACTGCATTCACTCCC
AATGGCACGTATCTGCAGCACCTGGCAAGGGACCCCACCTCAGGCACCCTCTACCTGGGGGCTACCAACTTCCTGTTCCAGCTGAGCCCT
GGGCTGCAGCTGGAGGCCACAGTGTCCACCGGCCCTGTGCTAGACAGCAGGGACTGCCTGCCACCTGTGATGCCTGATGAGTGCCCCCAG
GCCCAGCCTACCAACAACCCGAATCAGCTGCTCCTGGTGAGCCCAGGGGCCCTGGTGGTATGCGGGAGCGTGCACCAGGGGGTCTGTGAA
CAGCGGCGCCTGGGGCAGCTCGAGCAGCTGCTGCTGCGGCCAGAGCGGCCTGGGGACACACAATATGTGGCTGCCAATGATCCTGCGGTC
AGCACGGTGGGGCTGGTAGCCCAGGGCTTGGCAGGGGAGCCCCTCCTGTTTGTGGGGCGAGGATACACCAGCAGGGGTGTGGGGGGTGGC
ATTCCACCCATCACAACCCGGGCCCTGTGGCCGCCCGACCCCCAAGCTGCCTTCTCCTATGAGGAGACAGCCAAGCTGGCAGTGGGCCGC
CTCTCCGAGTACAGCCACCACTTCGTGAGTGCCTTTGCACGTGGGGCCAGCGCCTACTTCCTGTTCCTGCGGCGGGACCTGCAGGCTCAG
TCTAGAGCTTTTCGTGCCTATGTATCTCGAGTGTGTCTCCGGGACCAGCACTACTACTCCTATGTGGAGTTGCCTCTGGCCTGCGAAGGT
GGCCGCTACGGGCTGATCCAGGCTGCAGCTGTGGCCACGTCCAGGGAGGTGGCGCATGGGGAGGTGCTCTTTGCAGCTTTCTCCTCGGCT
GCACCCCCCACTGTGGGCCGGCCCCCATCGGCGGCTGCTGGGGCATCTGGAGCCTCTGCCCTCTGTGCCTTCCCCCTGGATGAGGTGGAC
CGGCTTGCTAATCGCACGCGAGATGCCTGCTACACCCGGGAGGGTCGTGCTGAGGATGGGACCGAGGTGGCCTACATCGAGTATGATGTC
AATTCTGACTGTGCACAGCTGCCAGTGGACACCCTGGATGCTTATCCCTGTGGCTCAGACCACACGCCCAGCCCCATGGCCAGCCGGGTC
CCGCTGGAAGCCACACCAATTCTGGAGTGGCCAGGGATTCAGCTAACAGCTGTGGCAGTCACCATGGAAGATGGACACACCATCGCTTTC
CTGGGTGATAGTCAAGGGCAGCTGCACAGGGTCTACTTGGGCCCAGGGAGCGATGGCCACCCATACTCCACACAGAGCATCCAGCAGGGG
TCTGCAGTGAGCAGAGACCTCACCTTTGATGGGACCTTTGAGCACCTGTATGTCATGACCCAGAGCACACTTCTGAAGGTTCCTGTGGCT
TCCTGTGCTCAGCACCTGGACTGTGCATCTTGCCTTGCTCACAGGGACCCATACTGTGGGTGGTGCGTGCTCCTTGGCAGGTGCAGTCGC
CGTTCTGAGTGCTCGAGGGGCCAGGGCCCAGAGCAGTGGCTATGGAGCTTCCAGCCTGAGCTGGGCTGTCTGCAAGTGGCAGCCATGAGT
CCTGCCAACATCAGCCGAGAGGAGACGAGGGAGGTTTTCCTATCAGTGCCAGACCTGCCACCCCTGTGGCCAGGGGAGTCATATTCCTGC
CACTTTGGGGAACATCAGAGTCCTGCCCTGCTGACTGGTTCTGGTGTGATGTGCCCCTCCCCAGACCCTAGTGAGGCCCCAGTGCTGCCG
AGAGGAGCCGACTACGTATCCGTGAGCGTGGAGCTCAGATTTGGCGCTGTTGTGATCGCCAAAACTTCCCTCTCTTTCTATGACTGTGTG
GCGGTCACTGAACTCCGCCCATCTGCGCAGTGCCAGGCCTGTGTGAGCAGCCGCTGGGGGTGTAACTGGTGTGTCTGGCAGCACCTGTGC
ACCCACAAGGCCTCGTGTGATGCTGGGCCCATGGTTGCAAGCCATCAGAGCCCGCTTGTCTCCCCAGACCCTCCTGCAAGAGGTGATGGA
GACTCAGCAGAGCTTGAGGGCCCTCCCGCCCCCCTCATCCTCCCGTCCAGCCTCGACTACCAGTATGACACCCCCGGGCTCTGGGAGCTG
GCCCCACTACTCTGTCCTGGGGCAGGTGCCAGACACGGATATTTACAGAGATGTGGCAGAGTACTCAGAGGCCAAGGAAGTCCGGGGGGT
GAAGGTCTTCCGCTCCTCGGCCACCGTGTACTTTGCCAATGCTGAGTTCTACAGTGATGCGCTGAAGCAGAGGTGTGGTGTGGATGTCGA
CTTCCTCATCTCCCAGAAGAAGAAACTGCTCAAGAAGCAGGAGCAGCTGAAGCTGAAGCAACTGCAGAAAGAGGAGAAGCTTCGGAAACA
GGCTGCCTCCCCCAAGGGCGCCTCAGTTTCCATTAATGTCAACACCAGCCTTGAAGACATGAGGAGCAACAACGTTGAGGACTGCAAGAT
GATGGTGAGCTCAGGAGATAAGATGGAAGATGCAACAGCCAATGGTCAAGAAGACTCCAAGGCCCCAGATGGGTCCACACTGAAGGCCCT
GGGCCTGCCTCAGCCAGACTTCCACAGCCTCATCCTGGACCTGGGTGCCCTCTCCTTTGTGGACACTGTGTGCCTCAAGAGCCTGAAGAA
TATTTTCCATGACTTCCGGGAGATTGAGGTGGAGGTGTACATGGCGGCCTGCCACAGCCCTGTGGTCAGCCAGCTTGAGGCTGGGCACTT
CTTCGATGCATCCATCACCAAGAAGCATCTCTTTGCCTCTGTCCATGATGCTGTCACCTTTGCCCTCCAACACCCGAGGCCTGTCCCCGA
CAGCCCTGTTTCGGTCACCAGACTCTGAACATGCTACATCCTGCCCAAGACTGCACCTCTGGAGGTGCAGGGCACCCTTGAGAAGCCCCT
CACCCCTAGGCCGCCTCCAGGTGCTACCCAGGAGTCCCCTCCATGTACACACACACAACTCAGGGAAGGAGGTCCTGGGACTCCAAGTTC
AGCGCTCCAGGTCTGGGACAGGGCCTGCATGCAGTCAGGCTGGCAGTGGCGCGGTACAGGGAGGGAACTGGTGCATATTTTAGCCTCAGG

>66557_66557_5_PLXNB1-SLC26A6_PLXNB1_chr3_48460986_ENST00000358459_SLC26A6_chr3_48667144_ENST00000420764_length(amino acids)=764AA_BP=720
MPALGPALLQALWAGWVLTLQPLPPTAFTPNGTYLQHLARDPTSGTLYLGATNFLFQLSPGLQLEATVSTGPVLDSRDCLPPVMPDECPQ
AQPTNNPNQLLLVSPGALVVCGSVHQGVCEQRRLGQLEQLLLRPERPGDTQYVAANDPAVSTVGLVAQGLAGEPLLFVGRGYTSRGVGGG
IPPITTRALWPPDPQAAFSYEETAKLAVGRLSEYSHHFVSAFARGASAYFLFLRRDLQAQSRAFRAYVSRVCLRDQHYYSYVELPLACEG
GRYGLIQAAAVATSREVAHGEVLFAAFSSAAPPTVGRPPSAAAGASGASALCAFPLDEVDRLANRTRDACYTREGRAEDGTEVAYIEYDV
NSDCAQLPVDTLDAYPCGSDHTPSPMASRVPLEATPILEWPGIQLTAVAVTMEDGHTIAFLGDSQGQLHRVYLGPGSDGHPYSTQSIQQG
SAVSRDLTFDGTFEHLYVMTQSTLLKVPVASCAQHLDCASCLAHRDPYCGWCVLLGRCSRRSECSRGQGPEQWLWSFQPELGCLQVAAMS
PANISREETREVFLSVPDLPPLWPGESYSCHFGEHQSPALLTGSGVMCPSPDPSEAPVLPRGADYVSVSVELRFGAVVIAKTSLSFYDCV
AVTELRPSAQCQACVSSRWGCNWCVWQHLCTHKASCDAGPMVASHQSPLVSPDPPARGDGDSAELEGPPAPLILPSSLDYQYDTPGLWEL

--------------------------------------------------------------
>66557_66557_6_PLXNB1-SLC26A6_PLXNB1_chr3_48460986_ENST00000358459_SLC26A6_chr3_48667144_ENST00000455886_length(transcript)=3421nt_BP=2430nt
GCCCGGCCGACGCGGCTTTGTCTCCTTTGTTCCCGGCGGTGGCAGCGCCGCGCGGGAGGGGCGGGCAGCGGGCGCAGTTTTCCGCCCCTC
GGTCTCCGGGTAACAGCTGCGGCTCCACCAGACCCGGGGAGAGGCCGCTGCGCGCGGAGCCCGAGCCCGGAGCGGCCGACGCCCGCCTCG
GCGCGCACATCCCGCGGGGCCCGGCCGGGTGGTGACTCCCACACGGGTCATGCTGTTGTCTCCTGATCCAGCCGGCCCTGCCAGGTGACC
ATGCCTGCTCTGGGCCCAGCTCTTCTCCAGGCTCTCTGGGCCGGGTGGGTCCTCACCCTCCAGCCCCTTCCACCAACTGCATTCACTCCC
AATGGCACGTATCTGCAGCACCTGGCAAGGGACCCCACCTCAGGCACCCTCTACCTGGGGGCTACCAACTTCCTGTTCCAGCTGAGCCCT
GGGCTGCAGCTGGAGGCCACAGTGTCCACCGGCCCTGTGCTAGACAGCAGGGACTGCCTGCCACCTGTGATGCCTGATGAGTGCCCCCAG
GCCCAGCCTACCAACAACCCGAATCAGCTGCTCCTGGTGAGCCCAGGGGCCCTGGTGGTATGCGGGAGCGTGCACCAGGGGGTCTGTGAA
CAGCGGCGCCTGGGGCAGCTCGAGCAGCTGCTGCTGCGGCCAGAGCGGCCTGGGGACACACAATATGTGGCTGCCAATGATCCTGCGGTC
AGCACGGTGGGGCTGGTAGCCCAGGGCTTGGCAGGGGAGCCCCTCCTGTTTGTGGGGCGAGGATACACCAGCAGGGGTGTGGGGGGTGGC
ATTCCACCCATCACAACCCGGGCCCTGTGGCCGCCCGACCCCCAAGCTGCCTTCTCCTATGAGGAGACAGCCAAGCTGGCAGTGGGCCGC
CTCTCCGAGTACAGCCACCACTTCGTGAGTGCCTTTGCACGTGGGGCCAGCGCCTACTTCCTGTTCCTGCGGCGGGACCTGCAGGCTCAG
TCTAGAGCTTTTCGTGCCTATGTATCTCGAGTGTGTCTCCGGGACCAGCACTACTACTCCTATGTGGAGTTGCCTCTGGCCTGCGAAGGT
GGCCGCTACGGGCTGATCCAGGCTGCAGCTGTGGCCACGTCCAGGGAGGTGGCGCATGGGGAGGTGCTCTTTGCAGCTTTCTCCTCGGCT
GCACCCCCCACTGTGGGCCGGCCCCCATCGGCGGCTGCTGGGGCATCTGGAGCCTCTGCCCTCTGTGCCTTCCCCCTGGATGAGGTGGAC
CGGCTTGCTAATCGCACGCGAGATGCCTGCTACACCCGGGAGGGTCGTGCTGAGGATGGGACCGAGGTGGCCTACATCGAGTATGATGTC
AATTCTGACTGTGCACAGCTGCCAGTGGACACCCTGGATGCTTATCCCTGTGGCTCAGACCACACGCCCAGCCCCATGGCCAGCCGGGTC
CCGCTGGAAGCCACACCAATTCTGGAGTGGCCAGGGATTCAGCTAACAGCTGTGGCAGTCACCATGGAAGATGGACACACCATCGCTTTC
CTGGGTGATAGTCAAGGGCAGCTGCACAGGGTCTACTTGGGCCCAGGGAGCGATGGCCACCCATACTCCACACAGAGCATCCAGCAGGGG
TCTGCAGTGAGCAGAGACCTCACCTTTGATGGGACCTTTGAGCACCTGTATGTCATGACCCAGAGCACACTTCTGAAGGTTCCTGTGGCT
TCCTGTGCTCAGCACCTGGACTGTGCATCTTGCCTTGCTCACAGGGACCCATACTGTGGGTGGTGCGTGCTCCTTGGCAGGTGCAGTCGC
CGTTCTGAGTGCTCGAGGGGCCAGGGCCCAGAGCAGTGGCTATGGAGCTTCCAGCCTGAGCTGGGCTGTCTGCAAGTGGCAGCCATGAGT
CCTGCCAACATCAGCCGAGAGGAGACGAGGGAGGTTTTCCTATCAGTGCCAGACCTGCCACCCCTGTGGCCAGGGGAGTCATATTCCTGC
CACTTTGGGGAACATCAGAGTCCTGCCCTGCTGACTGGTTCTGGTGTGATGTGCCCCTCCCCAGACCCTAGTGAGGCCCCAGTGCTGCCG
AGAGGAGCCGACTACGTATCCGTGAGCGTGGAGCTCAGATTTGGCGCTGTTGTGATCGCCAAAACTTCCCTCTCTTTCTATGACTGTGTG
GCGGTCACTGAACTCCGCCCATCTGCGCAGTGCCAGGCCTGTGTGAGCAGCCGCTGGGGGTGTAACTGGTGTGTCTGGCAGCACCTGTGC
ACCCACAAGGCCTCGTGTGATGCTGGGCCCATGGTTGCAAGCCATCAGAGCCCGCTTGTCTCCCCAGACCCTCCTGCAAGAGGTGATGGA
GACTCAGCAGAGCTTGAGGGCCCTCCCGCCCCCCTCATCCTCCCGTCCAGCCTCGACTACCAGTATGACACCCCCGGGCTCTGGGAGCTG
GCCCCACTACTCTGTCCTGGGGCAGGTGCCAGACACGGATATTTACAGAGATGTGGCAGAGTACTCAGAGGCCAAGGAAGTCCGGGGGGT
GAAGGTCTTCCGCTCCTCGGCCACCGTGTACTTTGCCAATGCTGAGTTCTACAGTGATGCGCTGAAGCAGAGGTGTGGTGTGGATGTCGA
CTTCCTCATCTCCCAGAAGAAGAAACTGCTCAAGAAGCAGGAGCAGCTGAAGCTGAAGCAACTGCAGAAAGAGGAGAAGCTTCGGAAACA
GGCTGCCTCCCCCAAGGGCGCCTCAGTTTCCATTAATGTCAACACCAGCCTTGAAGACATGAGGAGCAACAACGTTGAGGACTGCAAGAT
GATGCAGGTGAGCTCAGGAGATAAGATGGAAGATGCAACAGCCAATGGTCAAGAAGACTCCAAGGCCCCAGATGGGTCCACACTGAAGGC
CCTGGGCCTGCCTCAGCCAGACTTCCACAGCCTCATCCTGGACCTGGGTGCCCTCTCCTTTGTGGACACTGTGTGCCTCAAGAGCCTGAA
GAATATTTTCCATGACTTCCGGGAGATTGAGGTGGAGGTGTACATGGCGGCCTGCCACAGCCCTGTGGTCAGCCAGCTTGAGGCTGGGCA
CTTCTTCGATGCATCCATCACCAAGAAGCATCTCTTTGCCTCTGTCCATGATGCTGTCACCTTTGCCCTCCAACACCCGAGGCCTGTCCC
CGACAGCCCTGTTTCGGTCACCAGACTCTGAACATGCTACATCCTGCCCAAGACTGCACCTCTGGAGGTGCAGGGCACCCTTGAGAAGCC
CCTCACCCCTAGGCCGCCTCCAGGTGCTACCCAGGAGTCCCCTCCATGTACACACACACAACTCAGGGAAGGAGGTCCTGGGACTCCAAG
TTCAGCGCTCCAGGTCTGGGACAGGGCCTGCATGCAGTCAGGCTGGCAGTGGCGCGGTACAGGGAGGGAACTGGTGCATATTTTAGCCTC

>66557_66557_6_PLXNB1-SLC26A6_PLXNB1_chr3_48460986_ENST00000358459_SLC26A6_chr3_48667144_ENST00000455886_length(amino acids)=764AA_BP=720
MPALGPALLQALWAGWVLTLQPLPPTAFTPNGTYLQHLARDPTSGTLYLGATNFLFQLSPGLQLEATVSTGPVLDSRDCLPPVMPDECPQ
AQPTNNPNQLLLVSPGALVVCGSVHQGVCEQRRLGQLEQLLLRPERPGDTQYVAANDPAVSTVGLVAQGLAGEPLLFVGRGYTSRGVGGG
IPPITTRALWPPDPQAAFSYEETAKLAVGRLSEYSHHFVSAFARGASAYFLFLRRDLQAQSRAFRAYVSRVCLRDQHYYSYVELPLACEG
GRYGLIQAAAVATSREVAHGEVLFAAFSSAAPPTVGRPPSAAAGASGASALCAFPLDEVDRLANRTRDACYTREGRAEDGTEVAYIEYDV
NSDCAQLPVDTLDAYPCGSDHTPSPMASRVPLEATPILEWPGIQLTAVAVTMEDGHTIAFLGDSQGQLHRVYLGPGSDGHPYSTQSIQQG
SAVSRDLTFDGTFEHLYVMTQSTLLKVPVASCAQHLDCASCLAHRDPYCGWCVLLGRCSRRSECSRGQGPEQWLWSFQPELGCLQVAAMS
PANISREETREVFLSVPDLPPLWPGESYSCHFGEHQSPALLTGSGVMCPSPDPSEAPVLPRGADYVSVSVELRFGAVVIAKTSLSFYDCV
AVTELRPSAQCQACVSSRWGCNWCVWQHLCTHKASCDAGPMVASHQSPLVSPDPPARGDGDSAELEGPPAPLILPSSLDYQYDTPGLWEL

--------------------------------------------------------------
>66557_66557_7_PLXNB1-SLC26A6_PLXNB1_chr3_48460986_ENST00000358536_SLC26A6_chr3_48667144_ENST00000337000_length(transcript)=3988nt_BP=2979nt
GCCCGGCCGACGCGGCTTTGTCTCCTTTGTTCCCGGCGGTGGCAGCGCCGCGCGGGAGGGGCGGGCAGCGGGCGCAGTTTTCCGCCCCTC
GGTCTCCGGGTAACAGCTGCGGCTCCACCAGACCCGGGGAGAGGCCGCTGCGCGCGGAGCCCGAGCCCGGAGCGGCCGACGCCCGCCTCG
GCGCGCACATCCCGCGGGGCCCGGCCGGGTGGTGACTCCCACACGGGTCATGCTGTTGTCTCCTGATCCAGCCGGCCCTGCCAGGTGACC
ATGCCTGCTCTGGGCCCAGCTCTTCTCCAGGCTCTCTGGGCCGGGTGGGTCCTCACCCTCCAGCCCCTTCCACCAACTGCATTCACTCCC
AATGGCACGTATCTGCAGCACCTGGCAAGGGACCCCACCTCAGGCACCCTCTACCTGGGGGCTACCAACTTCCTGTTCCAGCTGAGCCCT
GGGCTGCAGCTGGAGGCCACAGTGTCCACCGGCCCTGTGCTAGACAGCAGGGACTGCCTGCCACCTGTGATGCCTGATGAGTGCCCCCAG
GCCCAGCCTACCAACAACCCGAATCAGCTGCTCCTGGTGAGCCCAGGGGCCCTGGTGGTATGCGGGAGCGTGCACCAGGGGGTCTGTGAA
CAGCGGCGCCTGGGGCAGCTCGAGCAGCTGCTGCTGCGGCCAGAGCGGCCTGGGGACACACAATATGTGGCTGCCAATGATCCTGCGGTC
AGCACGGTGGGGCTGGTAGCCCAGGGCTTGGCAGGGGAGCCCCTCCTGTTTGTGGGGCGAGGATACACCAGCAGGGGTGTGGGGGGTGGC
ATTCCACCCATCACAACCCGGGCCCTGTGGCCGCCCGACCCCCAAGCTGCCTTCTCCTATGAGGAGACAGCCAAGCTGGCAGTGGGCCGC
CTCTCCGAGTACAGCCACCACTTCGTGAGTGCCTTTGCACGTGGGGCCAGCGCCTACTTCCTGTTCCTGCGGCGGGACCTGCAGGCTCAG
TCTAGAGCTTTTCGTGCCTATGTATCTCGAGTGTGTCTCCGGGACCAGCACTACTACTCCTATGTGGAGTTGCCTCTGGCCTGCGAAGGT
GGCCGCTACGGGCTGATCCAGGCTGCAGCTGTGGCCACGTCCAGGGAGGTGGCGCATGGGGAGGTGCTCTTTGCAGCTTTCTCCTCGGCT
GCACCCCCCACTGTGGGCCGGCCCCCATCGGCGGCTGCTGGGGCATCTGGAGCCTCTGCCCTCTGTGCCTTCCCCCTGGATGAGGTGGAC
CGGCTTGCTAATCGCACGCGAGATGCCTGCTACACCCGGGAGGGTCGTGCTGAGGATGGGACCGAGGTGGCCTACATCGAGTATGATGTC
AATTCTGACTGTGCACAGCTGCCAGTGGACACCCTGGATGCTTATCCCTGTGGCTCAGACCACACGCCCAGCCCCATGGCCAGCCGGGTC
CCGCTGGAAGCCACACCAATTCTGGAGTGGCCAGGGATTCAGCTAACAGCTGTGGCAGTCACCATGGAAGATGGACACACCATCGCTTTC
CTGGGTGATAGTCAAGGGCAGCTGCACAGGGTCTACTTGGGCCCAGGGAGCGATGGCCACCCATACTCCACACAGAGCATCCAGCAGGGG
TCTGCAGTGAGCAGAGACCTCACCTTTGATGGGACCTTTGAGCACCTGTATGTCATGACCCAGAGCACACTTCTGAAGGTTCCTGTGGCT
TCCTGTGCTCAGCACCTGGACTGTGCATCTTGCCTTGCTCACAGGGACCCATACTGTGGGTGGTGCGTGCTCCTTGGCAGGTGCAGTCGC
CGTTCTGAGTGCTCGAGGGGCCAGGGCCCAGAGCAGTGGCTATGGAGCTTCCAGCCTGAGCTGGGCTGTCTGCAAGTGGCAGCCATGAGT
CCTGCCAACATCAGCCGAGAGGAGACGAGGGAGGTTTTCCTATCAGTGCCAGACCTGCCACCCCTGTGGCCAGGGGAGTCATATTCCTGC
CACTTTGGGGAACATCAGAGTCCTGCCCTGCTGACTGGTTCTGGTGTGATGTGCCCCTCCCCAGACCCTAGTGAGGCCCCAGTGCTGCCG
AGAGGAGCCGACTACGTATCCGTGAGCGTGGAGCTCAGATTTGGCGCTGTTGTGATCGCCAAAACTTCCCTCTCTTTCTATGACTGTGTG
GCGGTCACTGAACTCCGCCCATCTGCGCAGTGCCAGGCCTGTGTGAGCAGCCGCTGGGGGTGTAACTGGTGTGTCTGGCAGCACCTGTGC
ACCCACAAGGCCTCGTGTGATGCTGGGCCCATGGTTGCAAGCCATCAGAGCCCGCTTGTCTCCCCAGACCCTCCTGCAAGAGGTGGACCC
AGCCCCTCCCCACCCACAGCCCCCAAAGCCCTGGCCACCCCTGCTCCTGACACCCTTCCCGTGGAGCCTGGGGCTCCCTCCACAGCCACA
GCTTCGGACATCTCACCTGGGGCTAGTCCTTCCCTGCTCAGCCCCTGGGGGCCATGGGCAGGTTCTGGCTCCATATCTTCCCCTGGCTCC
ACAGGGTCGCCTCTCCATGAGGAGCCCTCCCCTCCCAGCCCCCAAAATGGACCTGGAACCGCTGTCCCTGCCCCCACTGACTTCAGACCC
TCAGCCACACCTGAGGACCTCTTGGCCTCCCCGCTGTCACCGTCAGAGGTAGCAGCAGTGCCCCCTGCAGACCCTGGCCCCGAGGCTCTT
CATCCCACAGTGCCCCTGGACCTGCCCCCTGCCACTGTTCCTGCCACCACTTTCCCAGGGGCCATGGGCTCCGTGAAGCCCGCCCTGGAC
TGGCTCACGAGAGAAGGCGGCGAGCTGCCCGAGGCGGACGAGTGGACGGGGGGTGACGCACCCGCCTTCTCCACTTCCACCCTCCTCTCA
GGTGATGGAGACTCAGCAGAGCTTGAGGGCCCTCCCGCCCCCCTCATCCTCCCGTCCAGCCTCGACTACCAGTATGACACCCCCGGGCTC
TGGGAGCTGGCCCCACTACTCTGTCCTGGGGCAGGTGCCAGACACGGATATTTACAGAGATGTGGCAGAGTACTCAGAGGCCAAGGAAGT
CCGGGGGGTGAAGGTCTTCCGCTCCTCGGCCACCGTGTACTTTGCCAATGCTGAGTTCTACAGTGATGCGCTGAAGCAGAGGTGTGGTGT
GGATGTCGACTTCCTCATCTCCCAGAAGAAGAAACTGCTCAAGAAGCAGGAGCAGCTGAAGCTGAAGCAACTGCAGAAAGAGGAGAAGCT
TCGGAAACAGGCTGCCTCCCCCAAGGGCGCCTCAGTTTCCATTAATGTCAACACCAGCCTTGAAGACATGAGGAGCAACAACGTTGAGGA
CTGCAAGATGATGGTGAGCTCAGGAGATAAGATGGAAGATGCAACAGCCAATGGTCAAGAAGACTCCAAGGCCCCAGATGGGTCCACACT
GAAGGCCCTGGGCCTGCCTCAGCCAGACTTCCACAGCCTCATCCTGGACCTGGGTGCCCTCTCCTTTGTGGACACTGTGTGCCTCAAGAG
CCTGAAGAATATTTTCCATGACTTCCGGGAGATTGAGGTGGAGGTGTACATGGCGGCCTGCCACAGCCCTGTGGTCAGCCAGCTTGAGGC
TGGGCACTTCTTCGATGCATCCATCACCAAGAAGCATCTCTTTGCCTCTGTCCATGATGCTGTCACCTTTGCCCTCCAACACCCGAGGCC
TGTCCCCGACAGCCCTGTTTCGGTCACCAGACTCTGAACATGCTACATCCTGCCCAAGACTGCACCTCTGGAGGTGCAGGGCACCCTTGA
GAAGCCCCTCACCCCTAGGCCGCCTCCAGGTGCTACCCAGGAGTCCCCTCCATGTACACACACACAACTCAGGGAAGGAGGTCCTGGGAC
TCCAAGTTCAGCGCTCCAGGTCTGGGACAGGGCCTGCATGCAGTCAGGCTGGCAGTGGCGCGGTACAGGGAGGGAACTGGTGCATATTTT

>66557_66557_7_PLXNB1-SLC26A6_PLXNB1_chr3_48460986_ENST00000358536_SLC26A6_chr3_48667144_ENST00000337000_length(amino acids)=947AA_BP=903
MPALGPALLQALWAGWVLTLQPLPPTAFTPNGTYLQHLARDPTSGTLYLGATNFLFQLSPGLQLEATVSTGPVLDSRDCLPPVMPDECPQ
AQPTNNPNQLLLVSPGALVVCGSVHQGVCEQRRLGQLEQLLLRPERPGDTQYVAANDPAVSTVGLVAQGLAGEPLLFVGRGYTSRGVGGG
IPPITTRALWPPDPQAAFSYEETAKLAVGRLSEYSHHFVSAFARGASAYFLFLRRDLQAQSRAFRAYVSRVCLRDQHYYSYVELPLACEG
GRYGLIQAAAVATSREVAHGEVLFAAFSSAAPPTVGRPPSAAAGASGASALCAFPLDEVDRLANRTRDACYTREGRAEDGTEVAYIEYDV
NSDCAQLPVDTLDAYPCGSDHTPSPMASRVPLEATPILEWPGIQLTAVAVTMEDGHTIAFLGDSQGQLHRVYLGPGSDGHPYSTQSIQQG
SAVSRDLTFDGTFEHLYVMTQSTLLKVPVASCAQHLDCASCLAHRDPYCGWCVLLGRCSRRSECSRGQGPEQWLWSFQPELGCLQVAAMS
PANISREETREVFLSVPDLPPLWPGESYSCHFGEHQSPALLTGSGVMCPSPDPSEAPVLPRGADYVSVSVELRFGAVVIAKTSLSFYDCV
AVTELRPSAQCQACVSSRWGCNWCVWQHLCTHKASCDAGPMVASHQSPLVSPDPPARGGPSPSPPTAPKALATPAPDTLPVEPGAPSTAT
ASDISPGASPSLLSPWGPWAGSGSISSPGSTGSPLHEEPSPPSPQNGPGTAVPAPTDFRPSATPEDLLASPLSPSEVAAVPPADPGPEAL
HPTVPLDLPPATVPATTFPGAMGSVKPALDWLTREGGELPEADEWTGGDAPAFSTSTLLSGDGDSAELEGPPAPLILPSSLDYQYDTPGL

--------------------------------------------------------------
>66557_66557_8_PLXNB1-SLC26A6_PLXNB1_chr3_48460986_ENST00000358536_SLC26A6_chr3_48667144_ENST00000358747_length(transcript)=3991nt_BP=2979nt
GCCCGGCCGACGCGGCTTTGTCTCCTTTGTTCCCGGCGGTGGCAGCGCCGCGCGGGAGGGGCGGGCAGCGGGCGCAGTTTTCCGCCCCTC
GGTCTCCGGGTAACAGCTGCGGCTCCACCAGACCCGGGGAGAGGCCGCTGCGCGCGGAGCCCGAGCCCGGAGCGGCCGACGCCCGCCTCG
GCGCGCACATCCCGCGGGGCCCGGCCGGGTGGTGACTCCCACACGGGTCATGCTGTTGTCTCCTGATCCAGCCGGCCCTGCCAGGTGACC
ATGCCTGCTCTGGGCCCAGCTCTTCTCCAGGCTCTCTGGGCCGGGTGGGTCCTCACCCTCCAGCCCCTTCCACCAACTGCATTCACTCCC
AATGGCACGTATCTGCAGCACCTGGCAAGGGACCCCACCTCAGGCACCCTCTACCTGGGGGCTACCAACTTCCTGTTCCAGCTGAGCCCT
GGGCTGCAGCTGGAGGCCACAGTGTCCACCGGCCCTGTGCTAGACAGCAGGGACTGCCTGCCACCTGTGATGCCTGATGAGTGCCCCCAG
GCCCAGCCTACCAACAACCCGAATCAGCTGCTCCTGGTGAGCCCAGGGGCCCTGGTGGTATGCGGGAGCGTGCACCAGGGGGTCTGTGAA
CAGCGGCGCCTGGGGCAGCTCGAGCAGCTGCTGCTGCGGCCAGAGCGGCCTGGGGACACACAATATGTGGCTGCCAATGATCCTGCGGTC
AGCACGGTGGGGCTGGTAGCCCAGGGCTTGGCAGGGGAGCCCCTCCTGTTTGTGGGGCGAGGATACACCAGCAGGGGTGTGGGGGGTGGC
ATTCCACCCATCACAACCCGGGCCCTGTGGCCGCCCGACCCCCAAGCTGCCTTCTCCTATGAGGAGACAGCCAAGCTGGCAGTGGGCCGC
CTCTCCGAGTACAGCCACCACTTCGTGAGTGCCTTTGCACGTGGGGCCAGCGCCTACTTCCTGTTCCTGCGGCGGGACCTGCAGGCTCAG
TCTAGAGCTTTTCGTGCCTATGTATCTCGAGTGTGTCTCCGGGACCAGCACTACTACTCCTATGTGGAGTTGCCTCTGGCCTGCGAAGGT
GGCCGCTACGGGCTGATCCAGGCTGCAGCTGTGGCCACGTCCAGGGAGGTGGCGCATGGGGAGGTGCTCTTTGCAGCTTTCTCCTCGGCT
GCACCCCCCACTGTGGGCCGGCCCCCATCGGCGGCTGCTGGGGCATCTGGAGCCTCTGCCCTCTGTGCCTTCCCCCTGGATGAGGTGGAC
CGGCTTGCTAATCGCACGCGAGATGCCTGCTACACCCGGGAGGGTCGTGCTGAGGATGGGACCGAGGTGGCCTACATCGAGTATGATGTC
AATTCTGACTGTGCACAGCTGCCAGTGGACACCCTGGATGCTTATCCCTGTGGCTCAGACCACACGCCCAGCCCCATGGCCAGCCGGGTC
CCGCTGGAAGCCACACCAATTCTGGAGTGGCCAGGGATTCAGCTAACAGCTGTGGCAGTCACCATGGAAGATGGACACACCATCGCTTTC
CTGGGTGATAGTCAAGGGCAGCTGCACAGGGTCTACTTGGGCCCAGGGAGCGATGGCCACCCATACTCCACACAGAGCATCCAGCAGGGG
TCTGCAGTGAGCAGAGACCTCACCTTTGATGGGACCTTTGAGCACCTGTATGTCATGACCCAGAGCACACTTCTGAAGGTTCCTGTGGCT
TCCTGTGCTCAGCACCTGGACTGTGCATCTTGCCTTGCTCACAGGGACCCATACTGTGGGTGGTGCGTGCTCCTTGGCAGGTGCAGTCGC
CGTTCTGAGTGCTCGAGGGGCCAGGGCCCAGAGCAGTGGCTATGGAGCTTCCAGCCTGAGCTGGGCTGTCTGCAAGTGGCAGCCATGAGT
CCTGCCAACATCAGCCGAGAGGAGACGAGGGAGGTTTTCCTATCAGTGCCAGACCTGCCACCCCTGTGGCCAGGGGAGTCATATTCCTGC
CACTTTGGGGAACATCAGAGTCCTGCCCTGCTGACTGGTTCTGGTGTGATGTGCCCCTCCCCAGACCCTAGTGAGGCCCCAGTGCTGCCG
AGAGGAGCCGACTACGTATCCGTGAGCGTGGAGCTCAGATTTGGCGCTGTTGTGATCGCCAAAACTTCCCTCTCTTTCTATGACTGTGTG
GCGGTCACTGAACTCCGCCCATCTGCGCAGTGCCAGGCCTGTGTGAGCAGCCGCTGGGGGTGTAACTGGTGTGTCTGGCAGCACCTGTGC
ACCCACAAGGCCTCGTGTGATGCTGGGCCCATGGTTGCAAGCCATCAGAGCCCGCTTGTCTCCCCAGACCCTCCTGCAAGAGGTGGACCC
AGCCCCTCCCCACCCACAGCCCCCAAAGCCCTGGCCACCCCTGCTCCTGACACCCTTCCCGTGGAGCCTGGGGCTCCCTCCACAGCCACA
GCTTCGGACATCTCACCTGGGGCTAGTCCTTCCCTGCTCAGCCCCTGGGGGCCATGGGCAGGTTCTGGCTCCATATCTTCCCCTGGCTCC
ACAGGGTCGCCTCTCCATGAGGAGCCCTCCCCTCCCAGCCCCCAAAATGGACCTGGAACCGCTGTCCCTGCCCCCACTGACTTCAGACCC
TCAGCCACACCTGAGGACCTCTTGGCCTCCCCGCTGTCACCGTCAGAGGTAGCAGCAGTGCCCCCTGCAGACCCTGGCCCCGAGGCTCTT
CATCCCACAGTGCCCCTGGACCTGCCCCCTGCCACTGTTCCTGCCACCACTTTCCCAGGGGCCATGGGCTCCGTGAAGCCCGCCCTGGAC
TGGCTCACGAGAGAAGGCGGCGAGCTGCCCGAGGCGGACGAGTGGACGGGGGGTGACGCACCCGCCTTCTCCACTTCCACCCTCCTCTCA
GGTGATGGAGACTCAGCAGAGCTTGAGGGCCCTCCCGCCCCCCTCATCCTCCCGTCCAGCCTCGACTACCAGTATGACACCCCCGGGCTC
TGGGAGCTGGCCCCACTACTCTGTCCTGGGGCAGGTGCCAGACACGGATATTTACAGAGATGTGGCAGAGTACTCAGAGGCCAAGGAAGT
CCGGGGGGTGAAGGTCTTCCGCTCCTCGGCCACCGTGTACTTTGCCAATGCTGAGTTCTACAGTGATGCGCTGAAGCAGAGGTGTGGTGT
GGATGTCGACTTCCTCATCTCCCAGAAGAAGAAACTGCTCAAGAAGCAGGAGCAGCTGAAGCTGAAGCAACTGCAGAAAGAGGAGAAGCT
TCGGAAACAGGCTGCCTCCCCCAAGGGCGCCTCAGTTTCCATTAATGTCAACACCAGCCTTGAAGACATGAGGAGCAACAACGTTGAGGA
CTGCAAGATGATGCAGGTGAGCTCAGGAGATAAGATGGAAGATGCAACAGCCAATGGTCAAGAAGACTCCAAGGCCCCAGATGGGTCCAC
ACTGAAGGCCCTGGGCCTGCCTCAGCCAGACTTCCACAGCCTCATCCTGGACCTGGGTGCCCTCTCCTTTGTGGACACTGTGTGCCTCAA
GAGCCTGAAGAATATTTTCCATGACTTCCGGGAGATTGAGGTGGAGGTGTACATGGCGGCCTGCCACAGCCCTGTGGTCAGCCAGCTTGA
GGCTGGGCACTTCTTCGATGCATCCATCACCAAGAAGCATCTCTTTGCCTCTGTCCATGATGCTGTCACCTTTGCCCTCCAACACCCGAG
GCCTGTCCCCGACAGCCCTGTTTCGGTCACCAGACTCTGAACATGCTACATCCTGCCCAAGACTGCACCTCTGGAGGTGCAGGGCACCCT
TGAGAAGCCCCTCACCCCTAGGCCGCCTCCAGGTGCTACCCAGGAGTCCCCTCCATGTACACACACACAACTCAGGGAAGGAGGTCCTGG
GACTCCAAGTTCAGCGCTCCAGGTCTGGGACAGGGCCTGCATGCAGTCAGGCTGGCAGTGGCGCGGTACAGGGAGGGAACTGGTGCATAT

>66557_66557_8_PLXNB1-SLC26A6_PLXNB1_chr3_48460986_ENST00000358536_SLC26A6_chr3_48667144_ENST00000358747_length(amino acids)=947AA_BP=903
MPALGPALLQALWAGWVLTLQPLPPTAFTPNGTYLQHLARDPTSGTLYLGATNFLFQLSPGLQLEATVSTGPVLDSRDCLPPVMPDECPQ
AQPTNNPNQLLLVSPGALVVCGSVHQGVCEQRRLGQLEQLLLRPERPGDTQYVAANDPAVSTVGLVAQGLAGEPLLFVGRGYTSRGVGGG
IPPITTRALWPPDPQAAFSYEETAKLAVGRLSEYSHHFVSAFARGASAYFLFLRRDLQAQSRAFRAYVSRVCLRDQHYYSYVELPLACEG
GRYGLIQAAAVATSREVAHGEVLFAAFSSAAPPTVGRPPSAAAGASGASALCAFPLDEVDRLANRTRDACYTREGRAEDGTEVAYIEYDV
NSDCAQLPVDTLDAYPCGSDHTPSPMASRVPLEATPILEWPGIQLTAVAVTMEDGHTIAFLGDSQGQLHRVYLGPGSDGHPYSTQSIQQG
SAVSRDLTFDGTFEHLYVMTQSTLLKVPVASCAQHLDCASCLAHRDPYCGWCVLLGRCSRRSECSRGQGPEQWLWSFQPELGCLQVAAMS
PANISREETREVFLSVPDLPPLWPGESYSCHFGEHQSPALLTGSGVMCPSPDPSEAPVLPRGADYVSVSVELRFGAVVIAKTSLSFYDCV
AVTELRPSAQCQACVSSRWGCNWCVWQHLCTHKASCDAGPMVASHQSPLVSPDPPARGGPSPSPPTAPKALATPAPDTLPVEPGAPSTAT
ASDISPGASPSLLSPWGPWAGSGSISSPGSTGSPLHEEPSPPSPQNGPGTAVPAPTDFRPSATPEDLLASPLSPSEVAAVPPADPGPEAL
HPTVPLDLPPATVPATTFPGAMGSVKPALDWLTREGGELPEADEWTGGDAPAFSTSTLLSGDGDSAELEGPPAPLILPSSLDYQYDTPGL

--------------------------------------------------------------
>66557_66557_9_PLXNB1-SLC26A6_PLXNB1_chr3_48460986_ENST00000358536_SLC26A6_chr3_48667144_ENST00000383733_length(transcript)=3934nt_BP=2979nt
GCCCGGCCGACGCGGCTTTGTCTCCTTTGTTCCCGGCGGTGGCAGCGCCGCGCGGGAGGGGCGGGCAGCGGGCGCAGTTTTCCGCCCCTC
GGTCTCCGGGTAACAGCTGCGGCTCCACCAGACCCGGGGAGAGGCCGCTGCGCGCGGAGCCCGAGCCCGGAGCGGCCGACGCCCGCCTCG
GCGCGCACATCCCGCGGGGCCCGGCCGGGTGGTGACTCCCACACGGGTCATGCTGTTGTCTCCTGATCCAGCCGGCCCTGCCAGGTGACC
ATGCCTGCTCTGGGCCCAGCTCTTCTCCAGGCTCTCTGGGCCGGGTGGGTCCTCACCCTCCAGCCCCTTCCACCAACTGCATTCACTCCC
AATGGCACGTATCTGCAGCACCTGGCAAGGGACCCCACCTCAGGCACCCTCTACCTGGGGGCTACCAACTTCCTGTTCCAGCTGAGCCCT
GGGCTGCAGCTGGAGGCCACAGTGTCCACCGGCCCTGTGCTAGACAGCAGGGACTGCCTGCCACCTGTGATGCCTGATGAGTGCCCCCAG
GCCCAGCCTACCAACAACCCGAATCAGCTGCTCCTGGTGAGCCCAGGGGCCCTGGTGGTATGCGGGAGCGTGCACCAGGGGGTCTGTGAA
CAGCGGCGCCTGGGGCAGCTCGAGCAGCTGCTGCTGCGGCCAGAGCGGCCTGGGGACACACAATATGTGGCTGCCAATGATCCTGCGGTC
AGCACGGTGGGGCTGGTAGCCCAGGGCTTGGCAGGGGAGCCCCTCCTGTTTGTGGGGCGAGGATACACCAGCAGGGGTGTGGGGGGTGGC
ATTCCACCCATCACAACCCGGGCCCTGTGGCCGCCCGACCCCCAAGCTGCCTTCTCCTATGAGGAGACAGCCAAGCTGGCAGTGGGCCGC
CTCTCCGAGTACAGCCACCACTTCGTGAGTGCCTTTGCACGTGGGGCCAGCGCCTACTTCCTGTTCCTGCGGCGGGACCTGCAGGCTCAG
TCTAGAGCTTTTCGTGCCTATGTATCTCGAGTGTGTCTCCGGGACCAGCACTACTACTCCTATGTGGAGTTGCCTCTGGCCTGCGAAGGT
GGCCGCTACGGGCTGATCCAGGCTGCAGCTGTGGCCACGTCCAGGGAGGTGGCGCATGGGGAGGTGCTCTTTGCAGCTTTCTCCTCGGCT
GCACCCCCCACTGTGGGCCGGCCCCCATCGGCGGCTGCTGGGGCATCTGGAGCCTCTGCCCTCTGTGCCTTCCCCCTGGATGAGGTGGAC
CGGCTTGCTAATCGCACGCGAGATGCCTGCTACACCCGGGAGGGTCGTGCTGAGGATGGGACCGAGGTGGCCTACATCGAGTATGATGTC
AATTCTGACTGTGCACAGCTGCCAGTGGACACCCTGGATGCTTATCCCTGTGGCTCAGACCACACGCCCAGCCCCATGGCCAGCCGGGTC
CCGCTGGAAGCCACACCAATTCTGGAGTGGCCAGGGATTCAGCTAACAGCTGTGGCAGTCACCATGGAAGATGGACACACCATCGCTTTC
CTGGGTGATAGTCAAGGGCAGCTGCACAGGGTCTACTTGGGCCCAGGGAGCGATGGCCACCCATACTCCACACAGAGCATCCAGCAGGGG
TCTGCAGTGAGCAGAGACCTCACCTTTGATGGGACCTTTGAGCACCTGTATGTCATGACCCAGAGCACACTTCTGAAGGTTCCTGTGGCT
TCCTGTGCTCAGCACCTGGACTGTGCATCTTGCCTTGCTCACAGGGACCCATACTGTGGGTGGTGCGTGCTCCTTGGCAGGTGCAGTCGC
CGTTCTGAGTGCTCGAGGGGCCAGGGCCCAGAGCAGTGGCTATGGAGCTTCCAGCCTGAGCTGGGCTGTCTGCAAGTGGCAGCCATGAGT
CCTGCCAACATCAGCCGAGAGGAGACGAGGGAGGTTTTCCTATCAGTGCCAGACCTGCCACCCCTGTGGCCAGGGGAGTCATATTCCTGC
CACTTTGGGGAACATCAGAGTCCTGCCCTGCTGACTGGTTCTGGTGTGATGTGCCCCTCCCCAGACCCTAGTGAGGCCCCAGTGCTGCCG
AGAGGAGCCGACTACGTATCCGTGAGCGTGGAGCTCAGATTTGGCGCTGTTGTGATCGCCAAAACTTCCCTCTCTTTCTATGACTGTGTG
GCGGTCACTGAACTCCGCCCATCTGCGCAGTGCCAGGCCTGTGTGAGCAGCCGCTGGGGGTGTAACTGGTGTGTCTGGCAGCACCTGTGC
ACCCACAAGGCCTCGTGTGATGCTGGGCCCATGGTTGCAAGCCATCAGAGCCCGCTTGTCTCCCCAGACCCTCCTGCAAGAGGTGGACCC
AGCCCCTCCCCACCCACAGCCCCCAAAGCCCTGGCCACCCCTGCTCCTGACACCCTTCCCGTGGAGCCTGGGGCTCCCTCCACAGCCACA
GCTTCGGACATCTCACCTGGGGCTAGTCCTTCCCTGCTCAGCCCCTGGGGGCCATGGGCAGGTTCTGGCTCCATATCTTCCCCTGGCTCC
ACAGGGTCGCCTCTCCATGAGGAGCCCTCCCCTCCCAGCCCCCAAAATGGACCTGGAACCGCTGTCCCTGCCCCCACTGACTTCAGACCC
TCAGCCACACCTGAGGACCTCTTGGCCTCCCCGCTGTCACCGTCAGAGGTAGCAGCAGTGCCCCCTGCAGACCCTGGCCCCGAGGCTCTT
CATCCCACAGTGCCCCTGGACCTGCCCCCTGCCACTGTTCCTGCCACCACTTTCCCAGGGGCCATGGGCTCCGTGAAGCCCGCCCTGGAC
TGGCTCACGAGAGAAGGCGGCGAGCTGCCCGAGGCGGACGAGTGGACGGGGGGTGACGCACCCGCCTTCTCCACTTCCACCCTCCTCTCA
GGTGATGGAGACTCAGCAGAGCTTGAGGGCCCTCCCGCCCCCCTCATCCTCCCGTCCAGCCTCGACTACCAGTATGACACCCCCGGGCTC
TGGGAGCTGGCCCCACTACTCTGTCCTGGGGCAGGTGCCAGACACGGATATTTACAGAGATGTGGCAGAGTACTCAGAGGCCAAGGAAGT
CCGGGGGGTGAAGGTCTTCCGCTCCTCGGCCACCGTGTACTTTGCCAATGCTGAGTTCTACAGTGATGCGCTGAAGCAGAGGTGTGGTGT
GGATGTCGACTTCCTCATCTCCCAGAAGAAGAAACTGCTCAAGAAGCAGGAGCAGCTGAAGCTGAAGCAACTGCAGAAAGAGGAGAAGCT
TCGGAAACAGGCAGGGCCCCTTTTGTCTGCATGTCTGGCTCCCCAGCAGGTGAGCTCAGGAGATAAGATGGAAGATGCAACAGCCAATGG
TCAAGAAGACTCCAAGGCCCCAGATGGGTCCACACTGAAGGCCCTGGGCCTGCCTCAGCCAGACTTCCACAGCCTCATCCTGGACCTGGG
TGCCCTCTCCTTTGTGGACACTGTGTGCCTCAAGAGCCTGAAGAATATTTTCCATGACTTCCGGGAGATTGAGGTGGAGGTGTACATGGC
GGCCTGCCACAGCCCTGTGGTCAGCCAGCTTGAGGCTGGGCACTTCTTCGATGCATCCATCACCAAGAAGCATCTCTTTGCCTCTGTCCA
TGATGCTGTCACCTTTGCCCTCCAACACCCGAGGCCTGTCCCCGACAGCCCTGTTTCGGTCACCAGACTCTGAACATGCTACATCCTGCC
CAAGACTGCACCTCTGGAGGTGCAGGGCACCCTTGAGAAGCCCCTCACCCCTAGGCCGCCTCCAGGTGCTACCCAGGAGTCCCCTCCATG
TACACACACACAACTCAGGGAAGGAGGTCCTGGGACTCCAAGTTCAGCGCTCCAGGTCTGGGACAGGGCCTGCATGCAGTCAGGCTGGCA

>66557_66557_9_PLXNB1-SLC26A6_PLXNB1_chr3_48460986_ENST00000358536_SLC26A6_chr3_48667144_ENST00000383733_length(amino acids)=947AA_BP=903
MPALGPALLQALWAGWVLTLQPLPPTAFTPNGTYLQHLARDPTSGTLYLGATNFLFQLSPGLQLEATVSTGPVLDSRDCLPPVMPDECPQ
AQPTNNPNQLLLVSPGALVVCGSVHQGVCEQRRLGQLEQLLLRPERPGDTQYVAANDPAVSTVGLVAQGLAGEPLLFVGRGYTSRGVGGG
IPPITTRALWPPDPQAAFSYEETAKLAVGRLSEYSHHFVSAFARGASAYFLFLRRDLQAQSRAFRAYVSRVCLRDQHYYSYVELPLACEG
GRYGLIQAAAVATSREVAHGEVLFAAFSSAAPPTVGRPPSAAAGASGASALCAFPLDEVDRLANRTRDACYTREGRAEDGTEVAYIEYDV
NSDCAQLPVDTLDAYPCGSDHTPSPMASRVPLEATPILEWPGIQLTAVAVTMEDGHTIAFLGDSQGQLHRVYLGPGSDGHPYSTQSIQQG
SAVSRDLTFDGTFEHLYVMTQSTLLKVPVASCAQHLDCASCLAHRDPYCGWCVLLGRCSRRSECSRGQGPEQWLWSFQPELGCLQVAAMS
PANISREETREVFLSVPDLPPLWPGESYSCHFGEHQSPALLTGSGVMCPSPDPSEAPVLPRGADYVSVSVELRFGAVVIAKTSLSFYDCV
AVTELRPSAQCQACVSSRWGCNWCVWQHLCTHKASCDAGPMVASHQSPLVSPDPPARGGPSPSPPTAPKALATPAPDTLPVEPGAPSTAT
ASDISPGASPSLLSPWGPWAGSGSISSPGSTGSPLHEEPSPPSPQNGPGTAVPAPTDFRPSATPEDLLASPLSPSEVAAVPPADPGPEAL
HPTVPLDLPPATVPATTFPGAMGSVKPALDWLTREGGELPEADEWTGGDAPAFSTSTLLSGDGDSAELEGPPAPLILPSSLDYQYDTPGL

--------------------------------------------------------------
>66557_66557_10_PLXNB1-SLC26A6_PLXNB1_chr3_48460986_ENST00000358536_SLC26A6_chr3_48667144_ENST00000395550_length(transcript)=3991nt_BP=2979nt
GCCCGGCCGACGCGGCTTTGTCTCCTTTGTTCCCGGCGGTGGCAGCGCCGCGCGGGAGGGGCGGGCAGCGGGCGCAGTTTTCCGCCCCTC
GGTCTCCGGGTAACAGCTGCGGCTCCACCAGACCCGGGGAGAGGCCGCTGCGCGCGGAGCCCGAGCCCGGAGCGGCCGACGCCCGCCTCG
GCGCGCACATCCCGCGGGGCCCGGCCGGGTGGTGACTCCCACACGGGTCATGCTGTTGTCTCCTGATCCAGCCGGCCCTGCCAGGTGACC
ATGCCTGCTCTGGGCCCAGCTCTTCTCCAGGCTCTCTGGGCCGGGTGGGTCCTCACCCTCCAGCCCCTTCCACCAACTGCATTCACTCCC
AATGGCACGTATCTGCAGCACCTGGCAAGGGACCCCACCTCAGGCACCCTCTACCTGGGGGCTACCAACTTCCTGTTCCAGCTGAGCCCT
GGGCTGCAGCTGGAGGCCACAGTGTCCACCGGCCCTGTGCTAGACAGCAGGGACTGCCTGCCACCTGTGATGCCTGATGAGTGCCCCCAG
GCCCAGCCTACCAACAACCCGAATCAGCTGCTCCTGGTGAGCCCAGGGGCCCTGGTGGTATGCGGGAGCGTGCACCAGGGGGTCTGTGAA
CAGCGGCGCCTGGGGCAGCTCGAGCAGCTGCTGCTGCGGCCAGAGCGGCCTGGGGACACACAATATGTGGCTGCCAATGATCCTGCGGTC
AGCACGGTGGGGCTGGTAGCCCAGGGCTTGGCAGGGGAGCCCCTCCTGTTTGTGGGGCGAGGATACACCAGCAGGGGTGTGGGGGGTGGC
ATTCCACCCATCACAACCCGGGCCCTGTGGCCGCCCGACCCCCAAGCTGCCTTCTCCTATGAGGAGACAGCCAAGCTGGCAGTGGGCCGC
CTCTCCGAGTACAGCCACCACTTCGTGAGTGCCTTTGCACGTGGGGCCAGCGCCTACTTCCTGTTCCTGCGGCGGGACCTGCAGGCTCAG
TCTAGAGCTTTTCGTGCCTATGTATCTCGAGTGTGTCTCCGGGACCAGCACTACTACTCCTATGTGGAGTTGCCTCTGGCCTGCGAAGGT
GGCCGCTACGGGCTGATCCAGGCTGCAGCTGTGGCCACGTCCAGGGAGGTGGCGCATGGGGAGGTGCTCTTTGCAGCTTTCTCCTCGGCT
GCACCCCCCACTGTGGGCCGGCCCCCATCGGCGGCTGCTGGGGCATCTGGAGCCTCTGCCCTCTGTGCCTTCCCCCTGGATGAGGTGGAC
CGGCTTGCTAATCGCACGCGAGATGCCTGCTACACCCGGGAGGGTCGTGCTGAGGATGGGACCGAGGTGGCCTACATCGAGTATGATGTC
AATTCTGACTGTGCACAGCTGCCAGTGGACACCCTGGATGCTTATCCCTGTGGCTCAGACCACACGCCCAGCCCCATGGCCAGCCGGGTC
CCGCTGGAAGCCACACCAATTCTGGAGTGGCCAGGGATTCAGCTAACAGCTGTGGCAGTCACCATGGAAGATGGACACACCATCGCTTTC
CTGGGTGATAGTCAAGGGCAGCTGCACAGGGTCTACTTGGGCCCAGGGAGCGATGGCCACCCATACTCCACACAGAGCATCCAGCAGGGG
TCTGCAGTGAGCAGAGACCTCACCTTTGATGGGACCTTTGAGCACCTGTATGTCATGACCCAGAGCACACTTCTGAAGGTTCCTGTGGCT
TCCTGTGCTCAGCACCTGGACTGTGCATCTTGCCTTGCTCACAGGGACCCATACTGTGGGTGGTGCGTGCTCCTTGGCAGGTGCAGTCGC
CGTTCTGAGTGCTCGAGGGGCCAGGGCCCAGAGCAGTGGCTATGGAGCTTCCAGCCTGAGCTGGGCTGTCTGCAAGTGGCAGCCATGAGT
CCTGCCAACATCAGCCGAGAGGAGACGAGGGAGGTTTTCCTATCAGTGCCAGACCTGCCACCCCTGTGGCCAGGGGAGTCATATTCCTGC
CACTTTGGGGAACATCAGAGTCCTGCCCTGCTGACTGGTTCTGGTGTGATGTGCCCCTCCCCAGACCCTAGTGAGGCCCCAGTGCTGCCG
AGAGGAGCCGACTACGTATCCGTGAGCGTGGAGCTCAGATTTGGCGCTGTTGTGATCGCCAAAACTTCCCTCTCTTTCTATGACTGTGTG
GCGGTCACTGAACTCCGCCCATCTGCGCAGTGCCAGGCCTGTGTGAGCAGCCGCTGGGGGTGTAACTGGTGTGTCTGGCAGCACCTGTGC
ACCCACAAGGCCTCGTGTGATGCTGGGCCCATGGTTGCAAGCCATCAGAGCCCGCTTGTCTCCCCAGACCCTCCTGCAAGAGGTGGACCC
AGCCCCTCCCCACCCACAGCCCCCAAAGCCCTGGCCACCCCTGCTCCTGACACCCTTCCCGTGGAGCCTGGGGCTCCCTCCACAGCCACA
GCTTCGGACATCTCACCTGGGGCTAGTCCTTCCCTGCTCAGCCCCTGGGGGCCATGGGCAGGTTCTGGCTCCATATCTTCCCCTGGCTCC
ACAGGGTCGCCTCTCCATGAGGAGCCCTCCCCTCCCAGCCCCCAAAATGGACCTGGAACCGCTGTCCCTGCCCCCACTGACTTCAGACCC
TCAGCCACACCTGAGGACCTCTTGGCCTCCCCGCTGTCACCGTCAGAGGTAGCAGCAGTGCCCCCTGCAGACCCTGGCCCCGAGGCTCTT
CATCCCACAGTGCCCCTGGACCTGCCCCCTGCCACTGTTCCTGCCACCACTTTCCCAGGGGCCATGGGCTCCGTGAAGCCCGCCCTGGAC
TGGCTCACGAGAGAAGGCGGCGAGCTGCCCGAGGCGGACGAGTGGACGGGGGGTGACGCACCCGCCTTCTCCACTTCCACCCTCCTCTCA
GGTGATGGAGACTCAGCAGAGCTTGAGGGCCCTCCCGCCCCCCTCATCCTCCCGTCCAGCCTCGACTACCAGTATGACACCCCCGGGCTC
TGGGAGCTGGCCCCACTACTCTGTCCTGGGGCAGGTGCCAGACACGGATATTTACAGAGATGTGGCAGAGTACTCAGAGGCCAAGGAAGT
CCGGGGGGTGAAGGTCTTCCGCTCCTCGGCCACCGTGTACTTTGCCAATGCTGAGTTCTACAGTGATGCGCTGAAGCAGAGGTGTGGTGT
GGATGTCGACTTCCTCATCTCCCAGAAGAAGAAACTGCTCAAGAAGCAGGAGCAGCTGAAGCTGAAGCAACTGCAGAAAGAGGAGAAGCT
TCGGAAACAGGCTGCCTCCCCCAAGGGCGCCTCAGTTTCCATTAATGTCAACACCAGCCTTGAAGACATGAGGAGCAACAACGTTGAGGA
CTGCAAGATGATGCAGGTGAGCTCAGGAGATAAGATGGAAGATGCAACAGCCAATGGTCAAGAAGACTCCAAGGCCCCAGATGGGTCCAC
ACTGAAGGCCCTGGGCCTGCCTCAGCCAGACTTCCACAGCCTCATCCTGGACCTGGGTGCCCTCTCCTTTGTGGACACTGTGTGCCTCAA
GAGCCTGAAGAATATTTTCCATGACTTCCGGGAGATTGAGGTGGAGGTGTACATGGCGGCCTGCCACAGCCCTGTGGTCAGCCAGCTTGA
GGCTGGGCACTTCTTCGATGCATCCATCACCAAGAAGCATCTCTTTGCCTCTGTCCATGATGCTGTCACCTTTGCCCTCCAACACCCGAG
GCCTGTCCCCGACAGCCCTGTTTCGGTCACCAGACTCTGAACATGCTACATCCTGCCCAAGACTGCACCTCTGGAGGTGCAGGGCACCCT
TGAGAAGCCCCTCACCCCTAGGCCGCCTCCAGGTGCTACCCAGGAGTCCCCTCCATGTACACACACACAACTCAGGGAAGGAGGTCCTGG
GACTCCAAGTTCAGCGCTCCAGGTCTGGGACAGGGCCTGCATGCAGTCAGGCTGGCAGTGGCGCGGTACAGGGAGGGAACTGGTGCATAT

>66557_66557_10_PLXNB1-SLC26A6_PLXNB1_chr3_48460986_ENST00000358536_SLC26A6_chr3_48667144_ENST00000395550_length(amino acids)=947AA_BP=903
MPALGPALLQALWAGWVLTLQPLPPTAFTPNGTYLQHLARDPTSGTLYLGATNFLFQLSPGLQLEATVSTGPVLDSRDCLPPVMPDECPQ
AQPTNNPNQLLLVSPGALVVCGSVHQGVCEQRRLGQLEQLLLRPERPGDTQYVAANDPAVSTVGLVAQGLAGEPLLFVGRGYTSRGVGGG
IPPITTRALWPPDPQAAFSYEETAKLAVGRLSEYSHHFVSAFARGASAYFLFLRRDLQAQSRAFRAYVSRVCLRDQHYYSYVELPLACEG
GRYGLIQAAAVATSREVAHGEVLFAAFSSAAPPTVGRPPSAAAGASGASALCAFPLDEVDRLANRTRDACYTREGRAEDGTEVAYIEYDV
NSDCAQLPVDTLDAYPCGSDHTPSPMASRVPLEATPILEWPGIQLTAVAVTMEDGHTIAFLGDSQGQLHRVYLGPGSDGHPYSTQSIQQG
SAVSRDLTFDGTFEHLYVMTQSTLLKVPVASCAQHLDCASCLAHRDPYCGWCVLLGRCSRRSECSRGQGPEQWLWSFQPELGCLQVAAMS
PANISREETREVFLSVPDLPPLWPGESYSCHFGEHQSPALLTGSGVMCPSPDPSEAPVLPRGADYVSVSVELRFGAVVIAKTSLSFYDCV
AVTELRPSAQCQACVSSRWGCNWCVWQHLCTHKASCDAGPMVASHQSPLVSPDPPARGGPSPSPPTAPKALATPAPDTLPVEPGAPSTAT
ASDISPGASPSLLSPWGPWAGSGSISSPGSTGSPLHEEPSPPSPQNGPGTAVPAPTDFRPSATPEDLLASPLSPSEVAAVPPADPGPEAL
HPTVPLDLPPATVPATTFPGAMGSVKPALDWLTREGGELPEADEWTGGDAPAFSTSTLLSGDGDSAELEGPPAPLILPSSLDYQYDTPGL

--------------------------------------------------------------
>66557_66557_11_PLXNB1-SLC26A6_PLXNB1_chr3_48460986_ENST00000358536_SLC26A6_chr3_48667144_ENST00000420764_length(transcript)=3990nt_BP=2979nt
GCCCGGCCGACGCGGCTTTGTCTCCTTTGTTCCCGGCGGTGGCAGCGCCGCGCGGGAGGGGCGGGCAGCGGGCGCAGTTTTCCGCCCCTC
GGTCTCCGGGTAACAGCTGCGGCTCCACCAGACCCGGGGAGAGGCCGCTGCGCGCGGAGCCCGAGCCCGGAGCGGCCGACGCCCGCCTCG
GCGCGCACATCCCGCGGGGCCCGGCCGGGTGGTGACTCCCACACGGGTCATGCTGTTGTCTCCTGATCCAGCCGGCCCTGCCAGGTGACC
ATGCCTGCTCTGGGCCCAGCTCTTCTCCAGGCTCTCTGGGCCGGGTGGGTCCTCACCCTCCAGCCCCTTCCACCAACTGCATTCACTCCC
AATGGCACGTATCTGCAGCACCTGGCAAGGGACCCCACCTCAGGCACCCTCTACCTGGGGGCTACCAACTTCCTGTTCCAGCTGAGCCCT
GGGCTGCAGCTGGAGGCCACAGTGTCCACCGGCCCTGTGCTAGACAGCAGGGACTGCCTGCCACCTGTGATGCCTGATGAGTGCCCCCAG
GCCCAGCCTACCAACAACCCGAATCAGCTGCTCCTGGTGAGCCCAGGGGCCCTGGTGGTATGCGGGAGCGTGCACCAGGGGGTCTGTGAA
CAGCGGCGCCTGGGGCAGCTCGAGCAGCTGCTGCTGCGGCCAGAGCGGCCTGGGGACACACAATATGTGGCTGCCAATGATCCTGCGGTC
AGCACGGTGGGGCTGGTAGCCCAGGGCTTGGCAGGGGAGCCCCTCCTGTTTGTGGGGCGAGGATACACCAGCAGGGGTGTGGGGGGTGGC
ATTCCACCCATCACAACCCGGGCCCTGTGGCCGCCCGACCCCCAAGCTGCCTTCTCCTATGAGGAGACAGCCAAGCTGGCAGTGGGCCGC
CTCTCCGAGTACAGCCACCACTTCGTGAGTGCCTTTGCACGTGGGGCCAGCGCCTACTTCCTGTTCCTGCGGCGGGACCTGCAGGCTCAG
TCTAGAGCTTTTCGTGCCTATGTATCTCGAGTGTGTCTCCGGGACCAGCACTACTACTCCTATGTGGAGTTGCCTCTGGCCTGCGAAGGT
GGCCGCTACGGGCTGATCCAGGCTGCAGCTGTGGCCACGTCCAGGGAGGTGGCGCATGGGGAGGTGCTCTTTGCAGCTTTCTCCTCGGCT
GCACCCCCCACTGTGGGCCGGCCCCCATCGGCGGCTGCTGGGGCATCTGGAGCCTCTGCCCTCTGTGCCTTCCCCCTGGATGAGGTGGAC
CGGCTTGCTAATCGCACGCGAGATGCCTGCTACACCCGGGAGGGTCGTGCTGAGGATGGGACCGAGGTGGCCTACATCGAGTATGATGTC
AATTCTGACTGTGCACAGCTGCCAGTGGACACCCTGGATGCTTATCCCTGTGGCTCAGACCACACGCCCAGCCCCATGGCCAGCCGGGTC
CCGCTGGAAGCCACACCAATTCTGGAGTGGCCAGGGATTCAGCTAACAGCTGTGGCAGTCACCATGGAAGATGGACACACCATCGCTTTC
CTGGGTGATAGTCAAGGGCAGCTGCACAGGGTCTACTTGGGCCCAGGGAGCGATGGCCACCCATACTCCACACAGAGCATCCAGCAGGGG
TCTGCAGTGAGCAGAGACCTCACCTTTGATGGGACCTTTGAGCACCTGTATGTCATGACCCAGAGCACACTTCTGAAGGTTCCTGTGGCT
TCCTGTGCTCAGCACCTGGACTGTGCATCTTGCCTTGCTCACAGGGACCCATACTGTGGGTGGTGCGTGCTCCTTGGCAGGTGCAGTCGC
CGTTCTGAGTGCTCGAGGGGCCAGGGCCCAGAGCAGTGGCTATGGAGCTTCCAGCCTGAGCTGGGCTGTCTGCAAGTGGCAGCCATGAGT
CCTGCCAACATCAGCCGAGAGGAGACGAGGGAGGTTTTCCTATCAGTGCCAGACCTGCCACCCCTGTGGCCAGGGGAGTCATATTCCTGC
CACTTTGGGGAACATCAGAGTCCTGCCCTGCTGACTGGTTCTGGTGTGATGTGCCCCTCCCCAGACCCTAGTGAGGCCCCAGTGCTGCCG
AGAGGAGCCGACTACGTATCCGTGAGCGTGGAGCTCAGATTTGGCGCTGTTGTGATCGCCAAAACTTCCCTCTCTTTCTATGACTGTGTG
GCGGTCACTGAACTCCGCCCATCTGCGCAGTGCCAGGCCTGTGTGAGCAGCCGCTGGGGGTGTAACTGGTGTGTCTGGCAGCACCTGTGC
ACCCACAAGGCCTCGTGTGATGCTGGGCCCATGGTTGCAAGCCATCAGAGCCCGCTTGTCTCCCCAGACCCTCCTGCAAGAGGTGGACCC
AGCCCCTCCCCACCCACAGCCCCCAAAGCCCTGGCCACCCCTGCTCCTGACACCCTTCCCGTGGAGCCTGGGGCTCCCTCCACAGCCACA
GCTTCGGACATCTCACCTGGGGCTAGTCCTTCCCTGCTCAGCCCCTGGGGGCCATGGGCAGGTTCTGGCTCCATATCTTCCCCTGGCTCC
ACAGGGTCGCCTCTCCATGAGGAGCCCTCCCCTCCCAGCCCCCAAAATGGACCTGGAACCGCTGTCCCTGCCCCCACTGACTTCAGACCC
TCAGCCACACCTGAGGACCTCTTGGCCTCCCCGCTGTCACCGTCAGAGGTAGCAGCAGTGCCCCCTGCAGACCCTGGCCCCGAGGCTCTT
CATCCCACAGTGCCCCTGGACCTGCCCCCTGCCACTGTTCCTGCCACCACTTTCCCAGGGGCCATGGGCTCCGTGAAGCCCGCCCTGGAC
TGGCTCACGAGAGAAGGCGGCGAGCTGCCCGAGGCGGACGAGTGGACGGGGGGTGACGCACCCGCCTTCTCCACTTCCACCCTCCTCTCA
GGTGATGGAGACTCAGCAGAGCTTGAGGGCCCTCCCGCCCCCCTCATCCTCCCGTCCAGCCTCGACTACCAGTATGACACCCCCGGGCTC
TGGGAGCTGGCCCCACTACTCTGTCCTGGGGCAGGTGCCAGACACGGATATTTACAGAGATGTGGCAGAGTACTCAGAGGCCAAGGAAGT
CCGGGGGGTGAAGGTCTTCCGCTCCTCGGCCACCGTGTACTTTGCCAATGCTGAGTTCTACAGTGATGCGCTGAAGCAGAGGTGTGGTGT
GGATGTCGACTTCCTCATCTCCCAGAAGAAGAAACTGCTCAAGAAGCAGGAGCAGCTGAAGCTGAAGCAACTGCAGAAAGAGGAGAAGCT
TCGGAAACAGGCTGCCTCCCCCAAGGGCGCCTCAGTTTCCATTAATGTCAACACCAGCCTTGAAGACATGAGGAGCAACAACGTTGAGGA
CTGCAAGATGATGGTGAGCTCAGGAGATAAGATGGAAGATGCAACAGCCAATGGTCAAGAAGACTCCAAGGCCCCAGATGGGTCCACACT
GAAGGCCCTGGGCCTGCCTCAGCCAGACTTCCACAGCCTCATCCTGGACCTGGGTGCCCTCTCCTTTGTGGACACTGTGTGCCTCAAGAG
CCTGAAGAATATTTTCCATGACTTCCGGGAGATTGAGGTGGAGGTGTACATGGCGGCCTGCCACAGCCCTGTGGTCAGCCAGCTTGAGGC
TGGGCACTTCTTCGATGCATCCATCACCAAGAAGCATCTCTTTGCCTCTGTCCATGATGCTGTCACCTTTGCCCTCCAACACCCGAGGCC
TGTCCCCGACAGCCCTGTTTCGGTCACCAGACTCTGAACATGCTACATCCTGCCCAAGACTGCACCTCTGGAGGTGCAGGGCACCCTTGA
GAAGCCCCTCACCCCTAGGCCGCCTCCAGGTGCTACCCAGGAGTCCCCTCCATGTACACACACACAACTCAGGGAAGGAGGTCCTGGGAC
TCCAAGTTCAGCGCTCCAGGTCTGGGACAGGGCCTGCATGCAGTCAGGCTGGCAGTGGCGCGGTACAGGGAGGGAACTGGTGCATATTTT

>66557_66557_11_PLXNB1-SLC26A6_PLXNB1_chr3_48460986_ENST00000358536_SLC26A6_chr3_48667144_ENST00000420764_length(amino acids)=947AA_BP=903
MPALGPALLQALWAGWVLTLQPLPPTAFTPNGTYLQHLARDPTSGTLYLGATNFLFQLSPGLQLEATVSTGPVLDSRDCLPPVMPDECPQ
AQPTNNPNQLLLVSPGALVVCGSVHQGVCEQRRLGQLEQLLLRPERPGDTQYVAANDPAVSTVGLVAQGLAGEPLLFVGRGYTSRGVGGG
IPPITTRALWPPDPQAAFSYEETAKLAVGRLSEYSHHFVSAFARGASAYFLFLRRDLQAQSRAFRAYVSRVCLRDQHYYSYVELPLACEG
GRYGLIQAAAVATSREVAHGEVLFAAFSSAAPPTVGRPPSAAAGASGASALCAFPLDEVDRLANRTRDACYTREGRAEDGTEVAYIEYDV
NSDCAQLPVDTLDAYPCGSDHTPSPMASRVPLEATPILEWPGIQLTAVAVTMEDGHTIAFLGDSQGQLHRVYLGPGSDGHPYSTQSIQQG
SAVSRDLTFDGTFEHLYVMTQSTLLKVPVASCAQHLDCASCLAHRDPYCGWCVLLGRCSRRSECSRGQGPEQWLWSFQPELGCLQVAAMS
PANISREETREVFLSVPDLPPLWPGESYSCHFGEHQSPALLTGSGVMCPSPDPSEAPVLPRGADYVSVSVELRFGAVVIAKTSLSFYDCV
AVTELRPSAQCQACVSSRWGCNWCVWQHLCTHKASCDAGPMVASHQSPLVSPDPPARGGPSPSPPTAPKALATPAPDTLPVEPGAPSTAT
ASDISPGASPSLLSPWGPWAGSGSISSPGSTGSPLHEEPSPPSPQNGPGTAVPAPTDFRPSATPEDLLASPLSPSEVAAVPPADPGPEAL
HPTVPLDLPPATVPATTFPGAMGSVKPALDWLTREGGELPEADEWTGGDAPAFSTSTLLSGDGDSAELEGPPAPLILPSSLDYQYDTPGL

--------------------------------------------------------------
>66557_66557_12_PLXNB1-SLC26A6_PLXNB1_chr3_48460986_ENST00000358536_SLC26A6_chr3_48667144_ENST00000455886_length(transcript)=3970nt_BP=2979nt
GCCCGGCCGACGCGGCTTTGTCTCCTTTGTTCCCGGCGGTGGCAGCGCCGCGCGGGAGGGGCGGGCAGCGGGCGCAGTTTTCCGCCCCTC
GGTCTCCGGGTAACAGCTGCGGCTCCACCAGACCCGGGGAGAGGCCGCTGCGCGCGGAGCCCGAGCCCGGAGCGGCCGACGCCCGCCTCG
GCGCGCACATCCCGCGGGGCCCGGCCGGGTGGTGACTCCCACACGGGTCATGCTGTTGTCTCCTGATCCAGCCGGCCCTGCCAGGTGACC
ATGCCTGCTCTGGGCCCAGCTCTTCTCCAGGCTCTCTGGGCCGGGTGGGTCCTCACCCTCCAGCCCCTTCCACCAACTGCATTCACTCCC
AATGGCACGTATCTGCAGCACCTGGCAAGGGACCCCACCTCAGGCACCCTCTACCTGGGGGCTACCAACTTCCTGTTCCAGCTGAGCCCT
GGGCTGCAGCTGGAGGCCACAGTGTCCACCGGCCCTGTGCTAGACAGCAGGGACTGCCTGCCACCTGTGATGCCTGATGAGTGCCCCCAG
GCCCAGCCTACCAACAACCCGAATCAGCTGCTCCTGGTGAGCCCAGGGGCCCTGGTGGTATGCGGGAGCGTGCACCAGGGGGTCTGTGAA
CAGCGGCGCCTGGGGCAGCTCGAGCAGCTGCTGCTGCGGCCAGAGCGGCCTGGGGACACACAATATGTGGCTGCCAATGATCCTGCGGTC
AGCACGGTGGGGCTGGTAGCCCAGGGCTTGGCAGGGGAGCCCCTCCTGTTTGTGGGGCGAGGATACACCAGCAGGGGTGTGGGGGGTGGC
ATTCCACCCATCACAACCCGGGCCCTGTGGCCGCCCGACCCCCAAGCTGCCTTCTCCTATGAGGAGACAGCCAAGCTGGCAGTGGGCCGC
CTCTCCGAGTACAGCCACCACTTCGTGAGTGCCTTTGCACGTGGGGCCAGCGCCTACTTCCTGTTCCTGCGGCGGGACCTGCAGGCTCAG
TCTAGAGCTTTTCGTGCCTATGTATCTCGAGTGTGTCTCCGGGACCAGCACTACTACTCCTATGTGGAGTTGCCTCTGGCCTGCGAAGGT
GGCCGCTACGGGCTGATCCAGGCTGCAGCTGTGGCCACGTCCAGGGAGGTGGCGCATGGGGAGGTGCTCTTTGCAGCTTTCTCCTCGGCT
GCACCCCCCACTGTGGGCCGGCCCCCATCGGCGGCTGCTGGGGCATCTGGAGCCTCTGCCCTCTGTGCCTTCCCCCTGGATGAGGTGGAC
CGGCTTGCTAATCGCACGCGAGATGCCTGCTACACCCGGGAGGGTCGTGCTGAGGATGGGACCGAGGTGGCCTACATCGAGTATGATGTC
AATTCTGACTGTGCACAGCTGCCAGTGGACACCCTGGATGCTTATCCCTGTGGCTCAGACCACACGCCCAGCCCCATGGCCAGCCGGGTC
CCGCTGGAAGCCACACCAATTCTGGAGTGGCCAGGGATTCAGCTAACAGCTGTGGCAGTCACCATGGAAGATGGACACACCATCGCTTTC
CTGGGTGATAGTCAAGGGCAGCTGCACAGGGTCTACTTGGGCCCAGGGAGCGATGGCCACCCATACTCCACACAGAGCATCCAGCAGGGG
TCTGCAGTGAGCAGAGACCTCACCTTTGATGGGACCTTTGAGCACCTGTATGTCATGACCCAGAGCACACTTCTGAAGGTTCCTGTGGCT
TCCTGTGCTCAGCACCTGGACTGTGCATCTTGCCTTGCTCACAGGGACCCATACTGTGGGTGGTGCGTGCTCCTTGGCAGGTGCAGTCGC
CGTTCTGAGTGCTCGAGGGGCCAGGGCCCAGAGCAGTGGCTATGGAGCTTCCAGCCTGAGCTGGGCTGTCTGCAAGTGGCAGCCATGAGT
CCTGCCAACATCAGCCGAGAGGAGACGAGGGAGGTTTTCCTATCAGTGCCAGACCTGCCACCCCTGTGGCCAGGGGAGTCATATTCCTGC
CACTTTGGGGAACATCAGAGTCCTGCCCTGCTGACTGGTTCTGGTGTGATGTGCCCCTCCCCAGACCCTAGTGAGGCCCCAGTGCTGCCG
AGAGGAGCCGACTACGTATCCGTGAGCGTGGAGCTCAGATTTGGCGCTGTTGTGATCGCCAAAACTTCCCTCTCTTTCTATGACTGTGTG
GCGGTCACTGAACTCCGCCCATCTGCGCAGTGCCAGGCCTGTGTGAGCAGCCGCTGGGGGTGTAACTGGTGTGTCTGGCAGCACCTGTGC
ACCCACAAGGCCTCGTGTGATGCTGGGCCCATGGTTGCAAGCCATCAGAGCCCGCTTGTCTCCCCAGACCCTCCTGCAAGAGGTGGACCC
AGCCCCTCCCCACCCACAGCCCCCAAAGCCCTGGCCACCCCTGCTCCTGACACCCTTCCCGTGGAGCCTGGGGCTCCCTCCACAGCCACA
GCTTCGGACATCTCACCTGGGGCTAGTCCTTCCCTGCTCAGCCCCTGGGGGCCATGGGCAGGTTCTGGCTCCATATCTTCCCCTGGCTCC
ACAGGGTCGCCTCTCCATGAGGAGCCCTCCCCTCCCAGCCCCCAAAATGGACCTGGAACCGCTGTCCCTGCCCCCACTGACTTCAGACCC
TCAGCCACACCTGAGGACCTCTTGGCCTCCCCGCTGTCACCGTCAGAGGTAGCAGCAGTGCCCCCTGCAGACCCTGGCCCCGAGGCTCTT
CATCCCACAGTGCCCCTGGACCTGCCCCCTGCCACTGTTCCTGCCACCACTTTCCCAGGGGCCATGGGCTCCGTGAAGCCCGCCCTGGAC
TGGCTCACGAGAGAAGGCGGCGAGCTGCCCGAGGCGGACGAGTGGACGGGGGGTGACGCACCCGCCTTCTCCACTTCCACCCTCCTCTCA
GGTGATGGAGACTCAGCAGAGCTTGAGGGCCCTCCCGCCCCCCTCATCCTCCCGTCCAGCCTCGACTACCAGTATGACACCCCCGGGCTC
TGGGAGCTGGCCCCACTACTCTGTCCTGGGGCAGGTGCCAGACACGGATATTTACAGAGATGTGGCAGAGTACTCAGAGGCCAAGGAAGT
CCGGGGGGTGAAGGTCTTCCGCTCCTCGGCCACCGTGTACTTTGCCAATGCTGAGTTCTACAGTGATGCGCTGAAGCAGAGGTGTGGTGT
GGATGTCGACTTCCTCATCTCCCAGAAGAAGAAACTGCTCAAGAAGCAGGAGCAGCTGAAGCTGAAGCAACTGCAGAAAGAGGAGAAGCT
TCGGAAACAGGCTGCCTCCCCCAAGGGCGCCTCAGTTTCCATTAATGTCAACACCAGCCTTGAAGACATGAGGAGCAACAACGTTGAGGA
CTGCAAGATGATGCAGGTGAGCTCAGGAGATAAGATGGAAGATGCAACAGCCAATGGTCAAGAAGACTCCAAGGCCCCAGATGGGTCCAC
ACTGAAGGCCCTGGGCCTGCCTCAGCCAGACTTCCACAGCCTCATCCTGGACCTGGGTGCCCTCTCCTTTGTGGACACTGTGTGCCTCAA
GAGCCTGAAGAATATTTTCCATGACTTCCGGGAGATTGAGGTGGAGGTGTACATGGCGGCCTGCCACAGCCCTGTGGTCAGCCAGCTTGA
GGCTGGGCACTTCTTCGATGCATCCATCACCAAGAAGCATCTCTTTGCCTCTGTCCATGATGCTGTCACCTTTGCCCTCCAACACCCGAG
GCCTGTCCCCGACAGCCCTGTTTCGGTCACCAGACTCTGAACATGCTACATCCTGCCCAAGACTGCACCTCTGGAGGTGCAGGGCACCCT
TGAGAAGCCCCTCACCCCTAGGCCGCCTCCAGGTGCTACCCAGGAGTCCCCTCCATGTACACACACACAACTCAGGGAAGGAGGTCCTGG
GACTCCAAGTTCAGCGCTCCAGGTCTGGGACAGGGCCTGCATGCAGTCAGGCTGGCAGTGGCGCGGTACAGGGAGGGAACTGGTGCATAT

>66557_66557_12_PLXNB1-SLC26A6_PLXNB1_chr3_48460986_ENST00000358536_SLC26A6_chr3_48667144_ENST00000455886_length(amino acids)=947AA_BP=903
MPALGPALLQALWAGWVLTLQPLPPTAFTPNGTYLQHLARDPTSGTLYLGATNFLFQLSPGLQLEATVSTGPVLDSRDCLPPVMPDECPQ
AQPTNNPNQLLLVSPGALVVCGSVHQGVCEQRRLGQLEQLLLRPERPGDTQYVAANDPAVSTVGLVAQGLAGEPLLFVGRGYTSRGVGGG
IPPITTRALWPPDPQAAFSYEETAKLAVGRLSEYSHHFVSAFARGASAYFLFLRRDLQAQSRAFRAYVSRVCLRDQHYYSYVELPLACEG
GRYGLIQAAAVATSREVAHGEVLFAAFSSAAPPTVGRPPSAAAGASGASALCAFPLDEVDRLANRTRDACYTREGRAEDGTEVAYIEYDV
NSDCAQLPVDTLDAYPCGSDHTPSPMASRVPLEATPILEWPGIQLTAVAVTMEDGHTIAFLGDSQGQLHRVYLGPGSDGHPYSTQSIQQG
SAVSRDLTFDGTFEHLYVMTQSTLLKVPVASCAQHLDCASCLAHRDPYCGWCVLLGRCSRRSECSRGQGPEQWLWSFQPELGCLQVAAMS
PANISREETREVFLSVPDLPPLWPGESYSCHFGEHQSPALLTGSGVMCPSPDPSEAPVLPRGADYVSVSVELRFGAVVIAKTSLSFYDCV
AVTELRPSAQCQACVSSRWGCNWCVWQHLCTHKASCDAGPMVASHQSPLVSPDPPARGGPSPSPPTAPKALATPAPDTLPVEPGAPSTAT
ASDISPGASPSLLSPWGPWAGSGSISSPGSTGSPLHEEPSPPSPQNGPGTAVPAPTDFRPSATPEDLLASPLSPSEVAAVPPADPGPEAL
HPTVPLDLPPATVPATTFPGAMGSVKPALDWLTREGGELPEADEWTGGDAPAFSTSTLLSGDGDSAELEGPPAPLILPSSLDYQYDTPGL

--------------------------------------------------------------

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Fusion Gene PPI Analysis for PLXNB1-SLC26A6


check button Go to ChiPPI (Chimeric Protein-Protein interactions) to see the chimeric PPI interaction in

ChiPPI page.


check button Protein-protein interactors with each fusion partner protein in wild-type (BIOGRID-3.4.160)
HgeneHgene's interactorsTgeneTgene's interactors


check button - Retained PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenStill interaction with


check button - Lost PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


check button - Retained PPIs, but lost function due to frame-shift fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


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Related Drugs for PLXNB1-SLC26A6


check button Drugs targeting genes involved in this fusion gene.
(DrugBank Version 5.1.8 2021-05-08)
PartnerGeneUniProtAccDrugBank IDDrug nameDrug activityDrug typeDrug status

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Related Diseases for PLXNB1-SLC26A6


check button Diseases associated with fusion partners.
(DisGeNet 4.0)
PartnerGeneDisease IDDisease name# pubmedsSource