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Center for Computational Systems Medicine
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Fusion Gene Summary

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Fusion Gene ORF analysis

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Fusion Genomic Features

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Fusion Protein Features

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Fusion Gene Sequence

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Fusion Gene PPI analysis

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Related Drugs

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Related Diseases

Fusion gene:PMEL-TBC1D7 (FusionGDB2 ID:66609)

Fusion Gene Summary for PMEL-TBC1D7

check button Fusion gene summary
Fusion gene informationFusion gene name: PMEL-TBC1D7
Fusion gene ID: 66609
HgeneTgene
Gene symbol

PMEL

TBC1D7

Gene ID

6490

51256

Gene namepremelanosome proteinTBC1 domain family member 7
SynonymsD12S53E|ME20|ME20-M|ME20M|P1|P100|PMEL17|SI|SIL|SILV|gp100MGCPH|PIG51|TBC7
Cytomap

12q13.2

6p24.1

Type of geneprotein-codingprotein-coding
Descriptionmelanocyte protein PMELmelanocyte protein Pmel 17melanocyte protein mel 17melanocytes lineage-specific antigen GP100melanoma-associated ME20 antigenmelanosomal matrix protein17silver locus protein homologsilver, mouse, homolog ofTBC1 domain family member 7TS complex subunit 3cell migration-inducing protein 23
Modification date2020031320200313
UniProtAcc..
Ensembl transtripts involved in fusion geneENST00000360714, ENST00000449260, 
ENST00000536427, ENST00000539511, 
ENST00000548493, ENST00000548747, 
ENST00000550447, ENST00000550464, 
ENST00000552882, ENST00000548689, 
ENST00000607532, ENST00000343141, 
ENST00000356436, ENST00000379300, 
ENST00000379307, ENST00000607658, 
Fusion gene scores* DoF score8 X 5 X 2=804 X 3 X 3=36
# samples 84
** MAII scorelog2(8/80*10)=0log2(4/36*10)=0.15200309344505
effective Gene in Pan-Cancer Fusion Genes (eGinPCFGs).
DoF>8 and MAII>0
Context

PubMed: PMEL [Title/Abstract] AND TBC1D7 [Title/Abstract] AND fusion [Title/Abstract]

Most frequent breakpointPMEL(56359720)-TBC1D7(13321327), # samples:2
Anticipated loss of major functional domain due to fusion event.PMEL-TBC1D7 seems lost the major protein functional domain in Hgene partner, which is a essential gene due to the frame-shifted ORF.
* DoF score (Degree of Frequency) = # partners X # break points X # cancer types
** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10)

check button Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez
PartnerGeneGO IDGO termPubMed ID
HgenePMEL

GO:0032438

melanosome organization

11694580

TgeneTBC1D7

GO:0031398

positive regulation of protein ubiquitination

17658474

TgeneTBC1D7

GO:0043547

positive regulation of GTPase activity

17646400


check buttonFusion gene breakpoints across PMEL (5'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.
all structure

check buttonFusion gene breakpoints across TBC1D7 (3'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.
all structure

check button Fusion gene information from two resources (ChiTars 5.0 and ChimerDB 4.0)
* All genome coordinats were lifted-over on hg19.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
SourceDiseaseSampleHgeneHchrHbpHstrandTgeneTchrTbpTstrand
ChimerDB4SKCMTCGA-EB-A5SG-06APMELchr12

56359720

-TBC1D7chr6

13321327

-
ChimerDB4SKCMTCGA-EE-A29D-06APMELchr12

56359720

-TBC1D7chr6

13321327

-


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Fusion Gene ORF analysis for PMEL-TBC1D7

check button Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
ORFHenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrand
5CDS-5UTRENST00000360714ENST00000607532PMELchr12

56359720

-TBC1D7chr6

13321327

-
5CDS-5UTRENST00000449260ENST00000607532PMELchr12

56359720

-TBC1D7chr6

13321327

-
5CDS-5UTRENST00000536427ENST00000607532PMELchr12

56359720

-TBC1D7chr6

13321327

-
5CDS-5UTRENST00000539511ENST00000607532PMELchr12

56359720

-TBC1D7chr6

13321327

-
5CDS-5UTRENST00000548493ENST00000607532PMELchr12

56359720

-TBC1D7chr6

13321327

-
5CDS-5UTRENST00000548747ENST00000607532PMELchr12

56359720

-TBC1D7chr6

13321327

-
5CDS-5UTRENST00000550447ENST00000607532PMELchr12

56359720

-TBC1D7chr6

13321327

-
5CDS-5UTRENST00000550464ENST00000607532PMELchr12

56359720

-TBC1D7chr6

13321327

-
5CDS-5UTRENST00000552882ENST00000607532PMELchr12

56359720

-TBC1D7chr6

13321327

-
Frame-shiftENST00000449260ENST00000343141PMELchr12

56359720

-TBC1D7chr6

13321327

-
Frame-shiftENST00000449260ENST00000356436PMELchr12

56359720

-TBC1D7chr6

13321327

-
Frame-shiftENST00000449260ENST00000379300PMELchr12

56359720

-TBC1D7chr6

13321327

-
Frame-shiftENST00000449260ENST00000379307PMELchr12

56359720

-TBC1D7chr6

13321327

-
Frame-shiftENST00000449260ENST00000607658PMELchr12

56359720

-TBC1D7chr6

13321327

-
Frame-shiftENST00000548747ENST00000343141PMELchr12

56359720

-TBC1D7chr6

13321327

-
Frame-shiftENST00000548747ENST00000356436PMELchr12

56359720

-TBC1D7chr6

13321327

-
Frame-shiftENST00000548747ENST00000379300PMELchr12

56359720

-TBC1D7chr6

13321327

-
Frame-shiftENST00000548747ENST00000379307PMELchr12

56359720

-TBC1D7chr6

13321327

-
Frame-shiftENST00000548747ENST00000607658PMELchr12

56359720

-TBC1D7chr6

13321327

-
Frame-shiftENST00000550447ENST00000343141PMELchr12

56359720

-TBC1D7chr6

13321327

-
Frame-shiftENST00000550447ENST00000356436PMELchr12

56359720

-TBC1D7chr6

13321327

-
Frame-shiftENST00000550447ENST00000379300PMELchr12

56359720

-TBC1D7chr6

13321327

-
Frame-shiftENST00000550447ENST00000379307PMELchr12

56359720

-TBC1D7chr6

13321327

-
Frame-shiftENST00000550447ENST00000607658PMELchr12

56359720

-TBC1D7chr6

13321327

-
Frame-shiftENST00000550464ENST00000343141PMELchr12

56359720

-TBC1D7chr6

13321327

-
Frame-shiftENST00000550464ENST00000356436PMELchr12

56359720

-TBC1D7chr6

13321327

-
Frame-shiftENST00000550464ENST00000379300PMELchr12

56359720

-TBC1D7chr6

13321327

-
Frame-shiftENST00000550464ENST00000379307PMELchr12

56359720

-TBC1D7chr6

13321327

-
Frame-shiftENST00000550464ENST00000607658PMELchr12

56359720

-TBC1D7chr6

13321327

-
Frame-shiftENST00000552882ENST00000343141PMELchr12

56359720

-TBC1D7chr6

13321327

-
Frame-shiftENST00000552882ENST00000356436PMELchr12

56359720

-TBC1D7chr6

13321327

-
Frame-shiftENST00000552882ENST00000379300PMELchr12

56359720

-TBC1D7chr6

13321327

-
Frame-shiftENST00000552882ENST00000379307PMELchr12

56359720

-TBC1D7chr6

13321327

-
Frame-shiftENST00000552882ENST00000607658PMELchr12

56359720

-TBC1D7chr6

13321327

-
In-frameENST00000360714ENST00000343141PMELchr12

56359720

-TBC1D7chr6

13321327

-
In-frameENST00000360714ENST00000356436PMELchr12

56359720

-TBC1D7chr6

13321327

-
In-frameENST00000360714ENST00000379300PMELchr12

56359720

-TBC1D7chr6

13321327

-
In-frameENST00000360714ENST00000379307PMELchr12

56359720

-TBC1D7chr6

13321327

-
In-frameENST00000360714ENST00000607658PMELchr12

56359720

-TBC1D7chr6

13321327

-
In-frameENST00000536427ENST00000343141PMELchr12

56359720

-TBC1D7chr6

13321327

-
In-frameENST00000536427ENST00000356436PMELchr12

56359720

-TBC1D7chr6

13321327

-
In-frameENST00000536427ENST00000379300PMELchr12

56359720

-TBC1D7chr6

13321327

-
In-frameENST00000536427ENST00000379307PMELchr12

56359720

-TBC1D7chr6

13321327

-
In-frameENST00000536427ENST00000607658PMELchr12

56359720

-TBC1D7chr6

13321327

-
In-frameENST00000539511ENST00000343141PMELchr12

56359720

-TBC1D7chr6

13321327

-
In-frameENST00000539511ENST00000356436PMELchr12

56359720

-TBC1D7chr6

13321327

-
In-frameENST00000539511ENST00000379300PMELchr12

56359720

-TBC1D7chr6

13321327

-
In-frameENST00000539511ENST00000379307PMELchr12

56359720

-TBC1D7chr6

13321327

-
In-frameENST00000539511ENST00000607658PMELchr12

56359720

-TBC1D7chr6

13321327

-
In-frameENST00000548493ENST00000343141PMELchr12

56359720

-TBC1D7chr6

13321327

-
In-frameENST00000548493ENST00000356436PMELchr12

56359720

-TBC1D7chr6

13321327

-
In-frameENST00000548493ENST00000379300PMELchr12

56359720

-TBC1D7chr6

13321327

-
In-frameENST00000548493ENST00000379307PMELchr12

56359720

-TBC1D7chr6

13321327

-
In-frameENST00000548493ENST00000607658PMELchr12

56359720

-TBC1D7chr6

13321327

-
intron-3CDSENST00000548689ENST00000343141PMELchr12

56359720

-TBC1D7chr6

13321327

-
intron-3CDSENST00000548689ENST00000356436PMELchr12

56359720

-TBC1D7chr6

13321327

-
intron-3CDSENST00000548689ENST00000379300PMELchr12

56359720

-TBC1D7chr6

13321327

-
intron-3CDSENST00000548689ENST00000379307PMELchr12

56359720

-TBC1D7chr6

13321327

-
intron-3CDSENST00000548689ENST00000607658PMELchr12

56359720

-TBC1D7chr6

13321327

-
intron-5UTRENST00000548689ENST00000607532PMELchr12

56359720

-TBC1D7chr6

13321327

-

check buttonORFfinder result based on the fusion transcript sequence of in-frame fusion genes.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandSeq length
(transcript)		BP loci
(transcript)		Predicted start
(transcript)		Predicted stop
(transcript)		Seq length
(amino acids)
ENST00000536427PMELchr1256359720-ENST00000379300TBC1D7chr613321327-100316422852276
ENST00000536427PMELchr1256359720-ENST00000356436TBC1D7chr613321327-100316422852276
ENST00000536427PMELchr1256359720-ENST00000379307TBC1D7chr613321327-100016422852276
ENST00000536427PMELchr1256359720-ENST00000343141TBC1D7chr613321327-73916422714230
ENST00000536427PMELchr1256359720-ENST00000607658TBC1D7chr613321327-155016422651209
ENST00000539511PMELchr1256359720-ENST00000379300TBC1D7chr613321327-100316422852276
ENST00000539511PMELchr1256359720-ENST00000356436TBC1D7chr613321327-100316422852276
ENST00000539511PMELchr1256359720-ENST00000379307TBC1D7chr613321327-100016422852276
ENST00000539511PMELchr1256359720-ENST00000343141TBC1D7chr613321327-73916422714230
ENST00000539511PMELchr1256359720-ENST00000607658TBC1D7chr613321327-155016422651209
ENST00000360714PMELchr1256359720-ENST00000379300TBC1D7chr613321327-100316422852276
ENST00000360714PMELchr1256359720-ENST00000356436TBC1D7chr613321327-100316422852276
ENST00000360714PMELchr1256359720-ENST00000379307TBC1D7chr613321327-100016422852276
ENST00000360714PMELchr1256359720-ENST00000343141TBC1D7chr613321327-73916422714230
ENST00000360714PMELchr1256359720-ENST00000607658TBC1D7chr613321327-155016422651209
ENST00000548493PMELchr1256359720-ENST00000379300TBC1D7chr613321327-102518644874276
ENST00000548493PMELchr1256359720-ENST00000356436TBC1D7chr613321327-102518644874276
ENST00000548493PMELchr1256359720-ENST00000379307TBC1D7chr613321327-102218644874276
ENST00000548493PMELchr1256359720-ENST00000343141TBC1D7chr613321327-76118644736230
ENST00000548493PMELchr1256359720-ENST00000607658TBC1D7chr613321327-157218644673209

check buttonDeepORF prediction of the coding potential based on the fusion transcript sequence of in-frame fusion genes. DeepORF is a coding potential classifier based on convolutional neural network by comparing the real Ribo-seq data. If the no-coding score < 0.5 and coding score > 0.5, then the in-frame fusion transcript is predicted as being likely translated.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandNo-coding scoreCoding score
ENST00000536427ENST00000379300PMELchr1256359720-TBC1D7chr613321327-0.0011721460.9988279
ENST00000536427ENST00000356436PMELchr1256359720-TBC1D7chr613321327-0.0011721460.9988279
ENST00000536427ENST00000379307PMELchr1256359720-TBC1D7chr613321327-0.0011925590.99880743
ENST00000536427ENST00000343141PMELchr1256359720-TBC1D7chr613321327-0.0067984970.99320155
ENST00000536427ENST00000607658PMELchr1256359720-TBC1D7chr613321327-0.0012775930.9987224
ENST00000539511ENST00000379300PMELchr1256359720-TBC1D7chr613321327-0.0011721460.9988279
ENST00000539511ENST00000356436PMELchr1256359720-TBC1D7chr613321327-0.0011721460.9988279
ENST00000539511ENST00000379307PMELchr1256359720-TBC1D7chr613321327-0.0011925590.99880743
ENST00000539511ENST00000343141PMELchr1256359720-TBC1D7chr613321327-0.0067984970.99320155
ENST00000539511ENST00000607658PMELchr1256359720-TBC1D7chr613321327-0.0012775930.9987224
ENST00000360714ENST00000379300PMELchr1256359720-TBC1D7chr613321327-0.0011721460.9988279
ENST00000360714ENST00000356436PMELchr1256359720-TBC1D7chr613321327-0.0011721460.9988279
ENST00000360714ENST00000379307PMELchr1256359720-TBC1D7chr613321327-0.0011925590.99880743
ENST00000360714ENST00000343141PMELchr1256359720-TBC1D7chr613321327-0.0067984970.99320155
ENST00000360714ENST00000607658PMELchr1256359720-TBC1D7chr613321327-0.0012775930.9987224
ENST00000548493ENST00000379300PMELchr1256359720-TBC1D7chr613321327-0.0012973830.99870265
ENST00000548493ENST00000356436PMELchr1256359720-TBC1D7chr613321327-0.0012973830.99870265
ENST00000548493ENST00000379307PMELchr1256359720-TBC1D7chr613321327-0.0013141580.9986859
ENST00000548493ENST00000343141PMELchr1256359720-TBC1D7chr613321327-0.0072063110.9927937
ENST00000548493ENST00000607658PMELchr1256359720-TBC1D7chr613321327-0.001269940.99873

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Fusion Genomic Features for PMEL-TBC1D7


check buttonFusionAI prediction of the potential fusion gene breakpoint based on the pre-mature RNA sequence context (+/- 5kb of individual partner genes, total 20kb length sequence). FusionAI is a fusion gene breakpoint classifier based on convolutional neural network by comparing the fusion positive and negative sequence context of ~ 20K fusion gene data. From here, we can have the relative potentency of the 20K genomic sequence how individual sequnce will be likely used as the gene fusion breakpoints.
HgeneHchrHbpHstrandTgeneTchrTbpTstrand1-pp (fusion gene breakpoint)

check buttonDistribution of 44 human genomic features loci across 20kb length fusion breakpoint regions. We integrated a total of 44 different types of human genomic feature loci information across five big categories including virus integration sites, repeats, structural variants, chromatin states, and gene expression regulation. More details are in help page.
genomic feature

check buttonDistribution of 44 human genomic features loci across 20kb length fusion breakpoint regions that are ovelapped with the top 1% feature importance score regions. More details are in help page.

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Fusion Protein Features for PMEL-TBC1D7


check button Four levels of functional features of fusion genes
Go to FGviewer search page for the most frequent breakpoint (https://ccsmweb.uth.edu/FGviewer/chr12:56359720/chr6:13321327)
- FGviewer provides the online visualization of the retention search of the protein functional features across DNA, RNA, protein, and pathological levels.
- How to search
1. Put your fusion gene symbol.
2. Press the tab key until there will be shown the breakpoint information filled.
4. Go down and press 'Search' tab twice.
4. Go down to have the hyperlink of the search result.
5. Click the hyperlink.
6. See the FGviewer result for your fusion gene.
FGviewer

check buttonMain function of each fusion partner protein. (from UniProt)
HgeneTgene
..
FUNCTION: Transcriptional activator which is required for calcium-dependent dendritic growth and branching in cortical neurons. Recruits CREB-binding protein (CREBBP) to nuclear bodies. Component of the CREST-BRG1 complex, a multiprotein complex that regulates promoter activation by orchestrating a calcium-dependent release of a repressor complex and a recruitment of an activator complex. In resting neurons, transcription of the c-FOS promoter is inhibited by BRG1-dependent recruitment of a phospho-RB1-HDAC1 repressor complex. Upon calcium influx, RB1 is dephosphorylated by calcineurin, which leads to release of the repressor complex. At the same time, there is increased recruitment of CREBBP to the promoter by a CREST-dependent mechanism, which leads to transcriptional activation. The CREST-BRG1 complex also binds to the NR2B promoter, and activity-dependent induction of NR2B expression involves a release of HDAC1 and recruitment of CREBBP (By similarity). {ECO:0000250}.FUNCTION: Transcriptional activator which is required for calcium-dependent dendritic growth and branching in cortical neurons. Recruits CREB-binding protein (CREBBP) to nuclear bodies. Component of the CREST-BRG1 complex, a multiprotein complex that regulates promoter activation by orchestrating a calcium-dependent release of a repressor complex and a recruitment of an activator complex. In resting neurons, transcription of the c-FOS promoter is inhibited by BRG1-dependent recruitment of a phospho-RB1-HDAC1 repressor complex. Upon calcium influx, RB1 is dephosphorylated by calcineurin, which leads to release of the repressor complex. At the same time, there is increased recruitment of CREBBP to the promoter by a CREST-dependent mechanism, which leads to transcriptional activation. The CREST-BRG1 complex also binds to the NR2B promoter, and activity-dependent induction of NR2B expression involves a release of HDAC1 and recruitment of CREBBP (By similarity). {ECO:0000250}.

check buttonRetention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at

download page


* Minus value of BPloci means that the break pointn is located before the CDS.
- In-frame and retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
TgeneTBC1D7chr12:56359720chr6:13321327ENST000003793071750_23137267.0DomainRab-GAP TBC

- In-frame and not-retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
HgenePMELchr12:56359720chr6:13321327ENST00000449260-111255_29225669.0DomainPKD
HgenePMELchr12:56359720chr6:13321327ENST00000539511-210255_29225576.0DomainPKD
HgenePMELchr12:56359720chr6:13321327ENST00000548493-212255_29225662.0DomainPKD
HgenePMELchr12:56359720chr6:13321327ENST00000548747-111255_29225662.0DomainPKD
HgenePMELchr12:56359720chr6:13321327ENST00000550464-19255_29225576.0DomainPKD
HgenePMELchr12:56359720chr6:13321327ENST00000552882-212255_29225662.0DomainPKD
HgenePMELchr12:56359720chr6:13321327ENST00000449260-111315_44425669.0RegionNote=10 X 13 AA approximate tandem repeats%2C RPT domain
HgenePMELchr12:56359720chr6:13321327ENST00000539511-210315_44425576.0RegionNote=10 X 13 AA approximate tandem repeats%2C RPT domain
HgenePMELchr12:56359720chr6:13321327ENST00000548493-212315_44425662.0RegionNote=10 X 13 AA approximate tandem repeats%2C RPT domain
HgenePMELchr12:56359720chr6:13321327ENST00000548747-111315_44425662.0RegionNote=10 X 13 AA approximate tandem repeats%2C RPT domain
HgenePMELchr12:56359720chr6:13321327ENST00000550464-19315_44425576.0RegionNote=10 X 13 AA approximate tandem repeats%2C RPT domain
HgenePMELchr12:56359720chr6:13321327ENST00000552882-212315_44425662.0RegionNote=10 X 13 AA approximate tandem repeats%2C RPT domain
HgenePMELchr12:56359720chr6:13321327ENST00000449260-111315_32725669.0RepeatNote=1
HgenePMELchr12:56359720chr6:13321327ENST00000449260-111328_34025669.0RepeatNote=2
HgenePMELchr12:56359720chr6:13321327ENST00000449260-111341_35325669.0RepeatNote=3
HgenePMELchr12:56359720chr6:13321327ENST00000449260-111354_36625669.0RepeatNote=4
HgenePMELchr12:56359720chr6:13321327ENST00000449260-111367_37925669.0RepeatNote=5
HgenePMELchr12:56359720chr6:13321327ENST00000449260-111380_39225669.0RepeatNote=6
HgenePMELchr12:56359720chr6:13321327ENST00000449260-111393_40525669.0RepeatNote=7
HgenePMELchr12:56359720chr6:13321327ENST00000449260-111406_41825669.0RepeatNote=8
HgenePMELchr12:56359720chr6:13321327ENST00000449260-111419_43125669.0RepeatNote=9
HgenePMELchr12:56359720chr6:13321327ENST00000449260-111432_44425669.0RepeatNote=10
HgenePMELchr12:56359720chr6:13321327ENST00000539511-210315_32725576.0RepeatNote=1
HgenePMELchr12:56359720chr6:13321327ENST00000539511-210328_34025576.0RepeatNote=2
HgenePMELchr12:56359720chr6:13321327ENST00000539511-210341_35325576.0RepeatNote=3
HgenePMELchr12:56359720chr6:13321327ENST00000539511-210354_36625576.0RepeatNote=4
HgenePMELchr12:56359720chr6:13321327ENST00000539511-210367_37925576.0RepeatNote=5
HgenePMELchr12:56359720chr6:13321327ENST00000539511-210380_39225576.0RepeatNote=6
HgenePMELchr12:56359720chr6:13321327ENST00000539511-210393_40525576.0RepeatNote=7
HgenePMELchr12:56359720chr6:13321327ENST00000539511-210406_41825576.0RepeatNote=8
HgenePMELchr12:56359720chr6:13321327ENST00000539511-210419_43125576.0RepeatNote=9
HgenePMELchr12:56359720chr6:13321327ENST00000539511-210432_44425576.0RepeatNote=10
HgenePMELchr12:56359720chr6:13321327ENST00000548493-212315_32725662.0RepeatNote=1
HgenePMELchr12:56359720chr6:13321327ENST00000548493-212328_34025662.0RepeatNote=2
HgenePMELchr12:56359720chr6:13321327ENST00000548493-212341_35325662.0RepeatNote=3
HgenePMELchr12:56359720chr6:13321327ENST00000548493-212354_36625662.0RepeatNote=4
HgenePMELchr12:56359720chr6:13321327ENST00000548493-212367_37925662.0RepeatNote=5
HgenePMELchr12:56359720chr6:13321327ENST00000548493-212380_39225662.0RepeatNote=6
HgenePMELchr12:56359720chr6:13321327ENST00000548493-212393_40525662.0RepeatNote=7
HgenePMELchr12:56359720chr6:13321327ENST00000548493-212406_41825662.0RepeatNote=8
HgenePMELchr12:56359720chr6:13321327ENST00000548493-212419_43125662.0RepeatNote=9
HgenePMELchr12:56359720chr6:13321327ENST00000548493-212432_44425662.0RepeatNote=10
HgenePMELchr12:56359720chr6:13321327ENST00000548747-111315_32725662.0RepeatNote=1
HgenePMELchr12:56359720chr6:13321327ENST00000548747-111328_34025662.0RepeatNote=2
HgenePMELchr12:56359720chr6:13321327ENST00000548747-111341_35325662.0RepeatNote=3
HgenePMELchr12:56359720chr6:13321327ENST00000548747-111354_36625662.0RepeatNote=4
HgenePMELchr12:56359720chr6:13321327ENST00000548747-111367_37925662.0RepeatNote=5
HgenePMELchr12:56359720chr6:13321327ENST00000548747-111380_39225662.0RepeatNote=6
HgenePMELchr12:56359720chr6:13321327ENST00000548747-111393_40525662.0RepeatNote=7
HgenePMELchr12:56359720chr6:13321327ENST00000548747-111406_41825662.0RepeatNote=8
HgenePMELchr12:56359720chr6:13321327ENST00000548747-111419_43125662.0RepeatNote=9
HgenePMELchr12:56359720chr6:13321327ENST00000548747-111432_44425662.0RepeatNote=10
HgenePMELchr12:56359720chr6:13321327ENST00000550464-19315_32725576.0RepeatNote=1
HgenePMELchr12:56359720chr6:13321327ENST00000550464-19328_34025576.0RepeatNote=2
HgenePMELchr12:56359720chr6:13321327ENST00000550464-19341_35325576.0RepeatNote=3
HgenePMELchr12:56359720chr6:13321327ENST00000550464-19354_36625576.0RepeatNote=4
HgenePMELchr12:56359720chr6:13321327ENST00000550464-19367_37925576.0RepeatNote=5
HgenePMELchr12:56359720chr6:13321327ENST00000550464-19380_39225576.0RepeatNote=6
HgenePMELchr12:56359720chr6:13321327ENST00000550464-19393_40525576.0RepeatNote=7
HgenePMELchr12:56359720chr6:13321327ENST00000550464-19406_41825576.0RepeatNote=8
HgenePMELchr12:56359720chr6:13321327ENST00000550464-19419_43125576.0RepeatNote=9
HgenePMELchr12:56359720chr6:13321327ENST00000550464-19432_44425576.0RepeatNote=10
HgenePMELchr12:56359720chr6:13321327ENST00000552882-212315_32725662.0RepeatNote=1
HgenePMELchr12:56359720chr6:13321327ENST00000552882-212328_34025662.0RepeatNote=2
HgenePMELchr12:56359720chr6:13321327ENST00000552882-212341_35325662.0RepeatNote=3
HgenePMELchr12:56359720chr6:13321327ENST00000552882-212354_36625662.0RepeatNote=4
HgenePMELchr12:56359720chr6:13321327ENST00000552882-212367_37925662.0RepeatNote=5
HgenePMELchr12:56359720chr6:13321327ENST00000552882-212380_39225662.0RepeatNote=6
HgenePMELchr12:56359720chr6:13321327ENST00000552882-212393_40525662.0RepeatNote=7
HgenePMELchr12:56359720chr6:13321327ENST00000552882-212406_41825662.0RepeatNote=8
HgenePMELchr12:56359720chr6:13321327ENST00000552882-212419_43125662.0RepeatNote=9
HgenePMELchr12:56359720chr6:13321327ENST00000552882-212432_44425662.0RepeatNote=10
HgenePMELchr12:56359720chr6:13321327ENST00000449260-111470_59525669.0Topological domainLumenal
HgenePMELchr12:56359720chr6:13321327ENST00000449260-111617_66125669.0Topological domainCytoplasmic
HgenePMELchr12:56359720chr6:13321327ENST00000539511-210470_59525576.0Topological domainLumenal
HgenePMELchr12:56359720chr6:13321327ENST00000539511-210617_66125576.0Topological domainCytoplasmic
HgenePMELchr12:56359720chr6:13321327ENST00000548493-212470_59525662.0Topological domainLumenal
HgenePMELchr12:56359720chr6:13321327ENST00000548493-212617_66125662.0Topological domainCytoplasmic
HgenePMELchr12:56359720chr6:13321327ENST00000548747-111470_59525662.0Topological domainLumenal
HgenePMELchr12:56359720chr6:13321327ENST00000548747-111617_66125662.0Topological domainCytoplasmic
HgenePMELchr12:56359720chr6:13321327ENST00000550464-19470_59525576.0Topological domainLumenal
HgenePMELchr12:56359720chr6:13321327ENST00000550464-19617_66125576.0Topological domainCytoplasmic
HgenePMELchr12:56359720chr6:13321327ENST00000552882-212470_59525662.0Topological domainLumenal
HgenePMELchr12:56359720chr6:13321327ENST00000552882-212617_66125662.0Topological domainCytoplasmic
HgenePMELchr12:56359720chr6:13321327ENST00000449260-111596_61625669.0TransmembraneHelical
HgenePMELchr12:56359720chr6:13321327ENST00000539511-210596_61625576.0TransmembraneHelical
HgenePMELchr12:56359720chr6:13321327ENST00000548493-212596_61625662.0TransmembraneHelical
HgenePMELchr12:56359720chr6:13321327ENST00000548747-111596_61625662.0TransmembraneHelical
HgenePMELchr12:56359720chr6:13321327ENST00000550464-19596_61625576.0TransmembraneHelical
HgenePMELchr12:56359720chr6:13321327ENST00000552882-212596_61625662.0TransmembraneHelical
TgeneTBC1D7chr12:56359720chr6:13321327ENST000003431412750_23164248.0DomainRab-GAP TBC
TgeneTBC1D7chr12:56359720chr6:13321327ENST000003564362850_23164294.0DomainRab-GAP TBC
TgeneTBC1D7chr12:56359720chr6:13321327ENST000003793002850_23164294.0DomainRab-GAP TBC


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Fusion Gene Sequence for PMEL-TBC1D7


check button For in-frame fusion transcripts, we provide the fusion transcript sequences and fusion amino acid sequences. To have fusion amino acid sequence, we ran ORFfinder and chose the longest ORF among the all predicted ones.
>66609_66609_1_PMEL-TBC1D7_PMEL_chr12_56359720_ENST00000360714_TBC1D7_chr6_13321327_ENST00000343141_length(transcript)=739nt_BP=164nt
AGCCCAGCGCTCCTCCCCGCAAATGATCCCGCCCCAGGGGCCTATCCCAGTCCCCCCAGTGCCTTTGGTTGCTGGAGGGAAGAACACAAT
GGATCTGGTGCTAAAAAGATGCCTTCTTCATTTGGCTGTGATAGGTGCTTTGCTGGCTGTGGGGGCTACAAAAGGAATCTTGCCTCCACA
CCACGAGTCCCATGCCAAGGTGATGATGTATCGTAAGGAGCAGTACTTGGATGTCCTTCATGCCCTGAAAGTCGTTCGCTTTGTTAGTGA
TGCCACACCTCAGGCTGAAGTCTATCTCCGCATGTATCAGCTGGAGTCTGGGAAGTTACCTCGAAGTCCCTCTTTTCCACTGCCAAAAGC
GTTTGAACAATACTTGAATCTGGAAGATGGCAGACTGCTGACTCATCTGAGGATGTGTTCCGCGGCGCCCAAACTTCCTTATGATCTCTG
GTTCAAGAGGTGCTTTGCGGGATGTTTGCCTGAATCCAGTTTACAGAGGGTTTGGGATAAAGTTGTGAGTGGATCCTGTAAGATCCTAGT
TTTTGTAGCTGTCGAAATTTTATTAACCTTTAAAATAAAAGTTATGGCACTGAACAGTGCAGAGAAGATAACAAAGTTTCTGGAAAATAT
TCCCCAGGACAGCTCAGACGCGATCGTGAGCAAGGCCATTGACTTGTGGCACAAACACTGTGGGACCCCGGTCCATTCAAGCTGAACGCA

>66609_66609_1_PMEL-TBC1D7_PMEL_chr12_56359720_ENST00000360714_TBC1D7_chr6_13321327_ENST00000343141_length(amino acids)=230AA_BP=47
MIPPQGPIPVPPVPLVAGGKNTMDLVLKRCLLHLAVIGALLAVGATKGILPPHHESHAKVMMYRKEQYLDVLHALKVVRFVSDATPQAEV
YLRMYQLESGKLPRSPSFPLPKAFEQYLNLEDGRLLTHLRMCSAAPKLPYDLWFKRCFAGCLPESSLQRVWDKVVSGSCKILVFVAVEIL

--------------------------------------------------------------
>66609_66609_2_PMEL-TBC1D7_PMEL_chr12_56359720_ENST00000360714_TBC1D7_chr6_13321327_ENST00000356436_length(transcript)=1003nt_BP=164nt
AGCCCAGCGCTCCTCCCCGCAAATGATCCCGCCCCAGGGGCCTATCCCAGTCCCCCCAGTGCCTTTGGTTGCTGGAGGGAAGAACACAAT
GGATCTGGTGCTAAAAAGATGCCTTCTTCATTTGGCTGTGATAGGTGCTTTGCTGGCTGTGGGGGCTACAAAAGGAATCTTGCCTCCACA
CCACGAGTCCCATGCCAAGGTGATGATGTATCGTAAGGAGCAGTACTTGGATGTCCTTCATGCCCTGAAAGTCGTTCGCTTTGTTAGTGA
TGCCACACCTCAGGCTGAAGTCTATCTCCGCATGTATCAGCTGGAGTCTGGGAAGTTACCTCGAAGTCCCTCTTTTCCACTGGAGCCAGA
TGATGAAGTGTTTCTTGCCATAGCTAAAGCCATGGAGGAAATGGTGGAAGATAGTGTCGACTGTTACTGGATCACCCGACGCTTTGTGAA
CCAATTAAATACCAAGTACCGGGATTCCTTGCCCCAGTTGCCAAAAGCGTTTGAACAATACTTGAATCTGGAAGATGGCAGACTGCTGAC
TCATCTGAGGATGTGTTCCGCGGCGCCCAAACTTCCTTATGATCTCTGGTTCAAGAGGTGCTTTGCGGGATGTTTGCCTGAATCCAGTTT
ACAGAGGGTTTGGGATAAAGTTGTGAGTGGATCCTGTAAGATCCTAGTTTTTGTAGCTGTCGAAATTTTATTAACCTTTAAAATAAAAGT
TATGGCACTGAACAGTGCAGAGAAGATAACAAAGTTTCTGGAAAATATTCCCCAGGACAGCTCAGACGCGATCGTGAGCAAGGCCATTGA
CTTGTGGCACAAACACTGTGGGACCCCGGTCCATTCAAGCTGAACGCACCCGCTGGTTGTGGACCGTCTGCCAGGCACCACAGTGAGCAT
TGTGTTCTTGGCATGTGATCTGGGAAACTGATTGAATAATACACTTTTCTTGCTTTGGTGCTCAAAGTGGTTTTTTTCCCCCAATAAAAT

>66609_66609_2_PMEL-TBC1D7_PMEL_chr12_56359720_ENST00000360714_TBC1D7_chr6_13321327_ENST00000356436_length(amino acids)=276AA_BP=47
MIPPQGPIPVPPVPLVAGGKNTMDLVLKRCLLHLAVIGALLAVGATKGILPPHHESHAKVMMYRKEQYLDVLHALKVVRFVSDATPQAEV
YLRMYQLESGKLPRSPSFPLEPDDEVFLAIAKAMEEMVEDSVDCYWITRRFVNQLNTKYRDSLPQLPKAFEQYLNLEDGRLLTHLRMCSA
APKLPYDLWFKRCFAGCLPESSLQRVWDKVVSGSCKILVFVAVEILLTFKIKVMALNSAEKITKFLENIPQDSSDAIVSKAIDLWHKHCG

--------------------------------------------------------------
>66609_66609_3_PMEL-TBC1D7_PMEL_chr12_56359720_ENST00000360714_TBC1D7_chr6_13321327_ENST00000379300_length(transcript)=1003nt_BP=164nt
AGCCCAGCGCTCCTCCCCGCAAATGATCCCGCCCCAGGGGCCTATCCCAGTCCCCCCAGTGCCTTTGGTTGCTGGAGGGAAGAACACAAT
GGATCTGGTGCTAAAAAGATGCCTTCTTCATTTGGCTGTGATAGGTGCTTTGCTGGCTGTGGGGGCTACAAAAGGAATCTTGCCTCCACA
CCACGAGTCCCATGCCAAGGTGATGATGTATCGTAAGGAGCAGTACTTGGATGTCCTTCATGCCCTGAAAGTCGTTCGCTTTGTTAGTGA
TGCCACACCTCAGGCTGAAGTCTATCTCCGCATGTATCAGCTGGAGTCTGGGAAGTTACCTCGAAGTCCCTCTTTTCCACTGGAGCCAGA
TGATGAAGTGTTTCTTGCCATAGCTAAAGCCATGGAGGAAATGGTGGAAGATAGTGTCGACTGTTACTGGATCACCCGACGCTTTGTGAA
CCAATTAAATACCAAGTACCGGGATTCCTTGCCCCAGTTGCCAAAAGCGTTTGAACAATACTTGAATCTGGAAGATGGCAGACTGCTGAC
TCATCTGAGGATGTGTTCCGCGGCGCCCAAACTTCCTTATGATCTCTGGTTCAAGAGGTGCTTTGCGGGATGTTTGCCTGAATCCAGTTT
ACAGAGGGTTTGGGATAAAGTTGTGAGTGGATCCTGTAAGATCCTAGTTTTTGTAGCTGTCGAAATTTTATTAACCTTTAAAATAAAAGT
TATGGCACTGAACAGTGCAGAGAAGATAACAAAGTTTCTGGAAAATATTCCCCAGGACAGCTCAGACGCGATCGTGAGCAAGGCCATTGA
CTTGTGGCACAAACACTGTGGGACCCCGGTCCATTCAAGCTGAACGCACCCGCTGGTTGTGGACCGTCTGCCAGGCACCACAGTGAGCAT
TGTGTTCTTGGCATGTGATCTGGGAAACTGATTGAATAATACACTTTTCTTGCTTTGGTGCTCAAAGTGGTTTTTTTCCCCCAATAAAAT

>66609_66609_3_PMEL-TBC1D7_PMEL_chr12_56359720_ENST00000360714_TBC1D7_chr6_13321327_ENST00000379300_length(amino acids)=276AA_BP=47
MIPPQGPIPVPPVPLVAGGKNTMDLVLKRCLLHLAVIGALLAVGATKGILPPHHESHAKVMMYRKEQYLDVLHALKVVRFVSDATPQAEV
YLRMYQLESGKLPRSPSFPLEPDDEVFLAIAKAMEEMVEDSVDCYWITRRFVNQLNTKYRDSLPQLPKAFEQYLNLEDGRLLTHLRMCSA
APKLPYDLWFKRCFAGCLPESSLQRVWDKVVSGSCKILVFVAVEILLTFKIKVMALNSAEKITKFLENIPQDSSDAIVSKAIDLWHKHCG

--------------------------------------------------------------
>66609_66609_4_PMEL-TBC1D7_PMEL_chr12_56359720_ENST00000360714_TBC1D7_chr6_13321327_ENST00000379307_length(transcript)=1000nt_BP=164nt
AGCCCAGCGCTCCTCCCCGCAAATGATCCCGCCCCAGGGGCCTATCCCAGTCCCCCCAGTGCCTTTGGTTGCTGGAGGGAAGAACACAAT
GGATCTGGTGCTAAAAAGATGCCTTCTTCATTTGGCTGTGATAGGTGCTTTGCTGGCTGTGGGGGCTACAAAAGGAATCTTGCCTCCACA
CCACGAGTCCCATGCCAAGGTGATGATGTATCGTAAGGAGCAGTACTTGGATGTCCTTCATGCCCTGAAAGTCGTTCGCTTTGTTAGTGA
TGCCACACCTCAGGCTGAAGTCTATCTCCGCATGTATCAGCTGGAGTCTGGGAAGTTACCTCGAAGTCCCTCTTTTCCACTGGAGCCAGA
TGATGAAGTGTTTCTTGCCATAGCTAAAGCCATGGAGGAAATGGTGGAAGATAGTGTCGACTGTTACTGGATCACCCGACGCTTTGTGAA
CCAATTAAATACCAAGTACCGGGATTCCTTGCCCCAGTTGCCAAAAGCGTTTGAACAATACTTGAATCTGGAAGATGGCAGACTGCTGAC
TCATCTGAGGATGTGTTCCGCGGCGCCCAAACTTCCTTATGATCTCTGGTTCAAGAGGTGCTTTGCGGGATGTTTGCCTGAATCCAGTTT
ACAGAGGGTTTGGGATAAAGTTGTGAGTGGATCCTGTAAGATCCTAGTTTTTGTAGCTGTCGAAATTTTATTAACCTTTAAAATAAAAGT
TATGGCACTGAACAGTGCAGAGAAGATAACAAAGTTTCTGGAAAATATTCCCCAGGACAGCTCAGACGCGATCGTGAGCAAGGCCATTGA
CTTGTGGCACAAACACTGTGGGACCCCGGTCCATTCAAGCTGAACGCACCCGCTGGTTGTGGACCGTCTGCCAGGCACCACAGTGAGCAT
TGTGTTCTTGGCATGTGATCTGGGAAACTGATTGAATAATACACTTTTCTTGCTTTGGTGCTCAAAGTGGTTTTTTTCCCCCAATAAAAT

>66609_66609_4_PMEL-TBC1D7_PMEL_chr12_56359720_ENST00000360714_TBC1D7_chr6_13321327_ENST00000379307_length(amino acids)=276AA_BP=47
MIPPQGPIPVPPVPLVAGGKNTMDLVLKRCLLHLAVIGALLAVGATKGILPPHHESHAKVMMYRKEQYLDVLHALKVVRFVSDATPQAEV
YLRMYQLESGKLPRSPSFPLEPDDEVFLAIAKAMEEMVEDSVDCYWITRRFVNQLNTKYRDSLPQLPKAFEQYLNLEDGRLLTHLRMCSA
APKLPYDLWFKRCFAGCLPESSLQRVWDKVVSGSCKILVFVAVEILLTFKIKVMALNSAEKITKFLENIPQDSSDAIVSKAIDLWHKHCG

--------------------------------------------------------------
>66609_66609_5_PMEL-TBC1D7_PMEL_chr12_56359720_ENST00000360714_TBC1D7_chr6_13321327_ENST00000607658_length(transcript)=1550nt_BP=164nt
AGCCCAGCGCTCCTCCCCGCAAATGATCCCGCCCCAGGGGCCTATCCCAGTCCCCCCAGTGCCTTTGGTTGCTGGAGGGAAGAACACAAT
GGATCTGGTGCTAAAAAGATGCCTTCTTCATTTGGCTGTGATAGGTGCTTTGCTGGCTGTGGGGGCTACAAAAGGAATCTTGCCTCCACA
CCACGAGTCCCATGCCAAGGTGATGATGTATCGTAAGGAGCAGTACTTGGATGTCCTTCATGCCCTGAAAGTCGTTCGCTTTGTTAGTGA
TGCCACACCTCAGGCTGAAGTCTATCTCCGCATGTATCAGCTGGAGTCTGGGAAGTTACCTCGAAGTCCCTCTTTTCCACTGGAGCCAGA
TGATGAAGTGTTTCTTGCCATAGCTAAAGCCATGGAGGAAATGGTGGAAGATAGTGTCGACTGTTACTGGATCACCCGACGCTTTGTGAA
CCAATTAAATACCAAGTACCGGGATTCCTTGCCCCAGTTGCCAAAAGCGTTTGAACAATACTTGAATCTGGAAGATGGCAGACTGCTGAC
TCATCTGAGGATGTGTTCCGCGGCGCCCAAACTTCCTTATGATCTCTGGTTCAAGAGGTGCTTTGCGGGATGTTTGCCTGAATCCAGTTT
ACAGAGGCAAGGTTTGGGATAAAGTTGTGAGTGGATCCTGTAAGATCCTAGTTTTTGTAGCTGTCGAAATTTTATTAACCTTTAAAATAA
AAGTTATGGCACTGAACAGTGCAGAGAAGATAACAAAGTTTCTGGAAAATGTAAGTGTGCTTTGATTTGATTTTGAATCTGGAAATGAAG
TTACCTTAGCAAGTCAGATTTTCCTGTTACATTAGATTATTTCAGAGAAATAATTACATGATTTTAGAGAAATAATACCTTAGAATGTTT
CAGAGAATAATTATAATAATGATTATTTTAGGGAAATTATTTAAGAGAAATAATAATTTGATTTGATTTTGAATCTAGAAATGAAGTCAC
TTTAGCAAGTGAGATTTTCCTGTTACATTAGATTATTTCAGAGAAATCATACAGTGTATTTTTACATTATAAGAAACACTTTTCCCTGAA
AAAGTTTGGCCTAAAGTTGGCCTGAGGGTTAGTTTGCATCCTGTCTTTGGGAAATGATGGTCTGAGACCATCTCGTGAATGTGTCCACTT
AGAACCAGAGTCTCATCCTCCATGTGACTATCAGCAGGCATGTCAGGAAAAGGAATAGGTGGGATCTGTCATTTTACAATGAGTAATTTT
TGTCAGTTCAAAAGGGGTTCTGTATTTTGGAGGATTTTGTAAGCCATTTCATTTCTGTTACTGTCTCTGGTGTAGTCCCAGTTGGGTTTA
TTAATATACAGTATTAACCTAGTATATTGCTGAAAAAGGCAATGGTAATGAAATTAACTTTTCCCTCGCTATGTATCTTGGAATACCCTT
TACCAGGCAAGAAGTAGGATTAAAGAGACTTATGCCTGAATGATTTTCACAGAATCCAAAATCTATTCATTTTTAAAATAGTATTAACAT

>66609_66609_5_PMEL-TBC1D7_PMEL_chr12_56359720_ENST00000360714_TBC1D7_chr6_13321327_ENST00000607658_length(amino acids)=209AA_BP=47
MIPPQGPIPVPPVPLVAGGKNTMDLVLKRCLLHLAVIGALLAVGATKGILPPHHESHAKVMMYRKEQYLDVLHALKVVRFVSDATPQAEV
YLRMYQLESGKLPRSPSFPLEPDDEVFLAIAKAMEEMVEDSVDCYWITRRFVNQLNTKYRDSLPQLPKAFEQYLNLEDGRLLTHLRMCSA

--------------------------------------------------------------
>66609_66609_6_PMEL-TBC1D7_PMEL_chr12_56359720_ENST00000536427_TBC1D7_chr6_13321327_ENST00000343141_length(transcript)=739nt_BP=164nt
AGCCCAGCGCTCCTCCCCGCAAATGATCCCGCCCCAGGGGCCTATCCCAGTCCCCCCAGTGCCTTTGGTTGCTGGAGGGAAGAACACAAT
GGATCTGGTGCTAAAAAGATGCCTTCTTCATTTGGCTGTGATAGGTGCTTTGCTGGCTGTGGGGGCTACAAAAGGAATCTTGCCTCCACA
CCACGAGTCCCATGCCAAGGTGATGATGTATCGTAAGGAGCAGTACTTGGATGTCCTTCATGCCCTGAAAGTCGTTCGCTTTGTTAGTGA
TGCCACACCTCAGGCTGAAGTCTATCTCCGCATGTATCAGCTGGAGTCTGGGAAGTTACCTCGAAGTCCCTCTTTTCCACTGCCAAAAGC
GTTTGAACAATACTTGAATCTGGAAGATGGCAGACTGCTGACTCATCTGAGGATGTGTTCCGCGGCGCCCAAACTTCCTTATGATCTCTG
GTTCAAGAGGTGCTTTGCGGGATGTTTGCCTGAATCCAGTTTACAGAGGGTTTGGGATAAAGTTGTGAGTGGATCCTGTAAGATCCTAGT
TTTTGTAGCTGTCGAAATTTTATTAACCTTTAAAATAAAAGTTATGGCACTGAACAGTGCAGAGAAGATAACAAAGTTTCTGGAAAATAT
TCCCCAGGACAGCTCAGACGCGATCGTGAGCAAGGCCATTGACTTGTGGCACAAACACTGTGGGACCCCGGTCCATTCAAGCTGAACGCA

>66609_66609_6_PMEL-TBC1D7_PMEL_chr12_56359720_ENST00000536427_TBC1D7_chr6_13321327_ENST00000343141_length(amino acids)=230AA_BP=47
MIPPQGPIPVPPVPLVAGGKNTMDLVLKRCLLHLAVIGALLAVGATKGILPPHHESHAKVMMYRKEQYLDVLHALKVVRFVSDATPQAEV
YLRMYQLESGKLPRSPSFPLPKAFEQYLNLEDGRLLTHLRMCSAAPKLPYDLWFKRCFAGCLPESSLQRVWDKVVSGSCKILVFVAVEIL

--------------------------------------------------------------
>66609_66609_7_PMEL-TBC1D7_PMEL_chr12_56359720_ENST00000536427_TBC1D7_chr6_13321327_ENST00000356436_length(transcript)=1003nt_BP=164nt
AGCCCAGCGCTCCTCCCCGCAAATGATCCCGCCCCAGGGGCCTATCCCAGTCCCCCCAGTGCCTTTGGTTGCTGGAGGGAAGAACACAAT
GGATCTGGTGCTAAAAAGATGCCTTCTTCATTTGGCTGTGATAGGTGCTTTGCTGGCTGTGGGGGCTACAAAAGGAATCTTGCCTCCACA
CCACGAGTCCCATGCCAAGGTGATGATGTATCGTAAGGAGCAGTACTTGGATGTCCTTCATGCCCTGAAAGTCGTTCGCTTTGTTAGTGA
TGCCACACCTCAGGCTGAAGTCTATCTCCGCATGTATCAGCTGGAGTCTGGGAAGTTACCTCGAAGTCCCTCTTTTCCACTGGAGCCAGA
TGATGAAGTGTTTCTTGCCATAGCTAAAGCCATGGAGGAAATGGTGGAAGATAGTGTCGACTGTTACTGGATCACCCGACGCTTTGTGAA
CCAATTAAATACCAAGTACCGGGATTCCTTGCCCCAGTTGCCAAAAGCGTTTGAACAATACTTGAATCTGGAAGATGGCAGACTGCTGAC
TCATCTGAGGATGTGTTCCGCGGCGCCCAAACTTCCTTATGATCTCTGGTTCAAGAGGTGCTTTGCGGGATGTTTGCCTGAATCCAGTTT
ACAGAGGGTTTGGGATAAAGTTGTGAGTGGATCCTGTAAGATCCTAGTTTTTGTAGCTGTCGAAATTTTATTAACCTTTAAAATAAAAGT
TATGGCACTGAACAGTGCAGAGAAGATAACAAAGTTTCTGGAAAATATTCCCCAGGACAGCTCAGACGCGATCGTGAGCAAGGCCATTGA
CTTGTGGCACAAACACTGTGGGACCCCGGTCCATTCAAGCTGAACGCACCCGCTGGTTGTGGACCGTCTGCCAGGCACCACAGTGAGCAT
TGTGTTCTTGGCATGTGATCTGGGAAACTGATTGAATAATACACTTTTCTTGCTTTGGTGCTCAAAGTGGTTTTTTTCCCCCAATAAAAT

>66609_66609_7_PMEL-TBC1D7_PMEL_chr12_56359720_ENST00000536427_TBC1D7_chr6_13321327_ENST00000356436_length(amino acids)=276AA_BP=47
MIPPQGPIPVPPVPLVAGGKNTMDLVLKRCLLHLAVIGALLAVGATKGILPPHHESHAKVMMYRKEQYLDVLHALKVVRFVSDATPQAEV
YLRMYQLESGKLPRSPSFPLEPDDEVFLAIAKAMEEMVEDSVDCYWITRRFVNQLNTKYRDSLPQLPKAFEQYLNLEDGRLLTHLRMCSA
APKLPYDLWFKRCFAGCLPESSLQRVWDKVVSGSCKILVFVAVEILLTFKIKVMALNSAEKITKFLENIPQDSSDAIVSKAIDLWHKHCG

--------------------------------------------------------------
>66609_66609_8_PMEL-TBC1D7_PMEL_chr12_56359720_ENST00000536427_TBC1D7_chr6_13321327_ENST00000379300_length(transcript)=1003nt_BP=164nt
AGCCCAGCGCTCCTCCCCGCAAATGATCCCGCCCCAGGGGCCTATCCCAGTCCCCCCAGTGCCTTTGGTTGCTGGAGGGAAGAACACAAT
GGATCTGGTGCTAAAAAGATGCCTTCTTCATTTGGCTGTGATAGGTGCTTTGCTGGCTGTGGGGGCTACAAAAGGAATCTTGCCTCCACA
CCACGAGTCCCATGCCAAGGTGATGATGTATCGTAAGGAGCAGTACTTGGATGTCCTTCATGCCCTGAAAGTCGTTCGCTTTGTTAGTGA
TGCCACACCTCAGGCTGAAGTCTATCTCCGCATGTATCAGCTGGAGTCTGGGAAGTTACCTCGAAGTCCCTCTTTTCCACTGGAGCCAGA
TGATGAAGTGTTTCTTGCCATAGCTAAAGCCATGGAGGAAATGGTGGAAGATAGTGTCGACTGTTACTGGATCACCCGACGCTTTGTGAA
CCAATTAAATACCAAGTACCGGGATTCCTTGCCCCAGTTGCCAAAAGCGTTTGAACAATACTTGAATCTGGAAGATGGCAGACTGCTGAC
TCATCTGAGGATGTGTTCCGCGGCGCCCAAACTTCCTTATGATCTCTGGTTCAAGAGGTGCTTTGCGGGATGTTTGCCTGAATCCAGTTT
ACAGAGGGTTTGGGATAAAGTTGTGAGTGGATCCTGTAAGATCCTAGTTTTTGTAGCTGTCGAAATTTTATTAACCTTTAAAATAAAAGT
TATGGCACTGAACAGTGCAGAGAAGATAACAAAGTTTCTGGAAAATATTCCCCAGGACAGCTCAGACGCGATCGTGAGCAAGGCCATTGA
CTTGTGGCACAAACACTGTGGGACCCCGGTCCATTCAAGCTGAACGCACCCGCTGGTTGTGGACCGTCTGCCAGGCACCACAGTGAGCAT
TGTGTTCTTGGCATGTGATCTGGGAAACTGATTGAATAATACACTTTTCTTGCTTTGGTGCTCAAAGTGGTTTTTTTCCCCCAATAAAAT

>66609_66609_8_PMEL-TBC1D7_PMEL_chr12_56359720_ENST00000536427_TBC1D7_chr6_13321327_ENST00000379300_length(amino acids)=276AA_BP=47
MIPPQGPIPVPPVPLVAGGKNTMDLVLKRCLLHLAVIGALLAVGATKGILPPHHESHAKVMMYRKEQYLDVLHALKVVRFVSDATPQAEV
YLRMYQLESGKLPRSPSFPLEPDDEVFLAIAKAMEEMVEDSVDCYWITRRFVNQLNTKYRDSLPQLPKAFEQYLNLEDGRLLTHLRMCSA
APKLPYDLWFKRCFAGCLPESSLQRVWDKVVSGSCKILVFVAVEILLTFKIKVMALNSAEKITKFLENIPQDSSDAIVSKAIDLWHKHCG

--------------------------------------------------------------
>66609_66609_9_PMEL-TBC1D7_PMEL_chr12_56359720_ENST00000536427_TBC1D7_chr6_13321327_ENST00000379307_length(transcript)=1000nt_BP=164nt
AGCCCAGCGCTCCTCCCCGCAAATGATCCCGCCCCAGGGGCCTATCCCAGTCCCCCCAGTGCCTTTGGTTGCTGGAGGGAAGAACACAAT
GGATCTGGTGCTAAAAAGATGCCTTCTTCATTTGGCTGTGATAGGTGCTTTGCTGGCTGTGGGGGCTACAAAAGGAATCTTGCCTCCACA
CCACGAGTCCCATGCCAAGGTGATGATGTATCGTAAGGAGCAGTACTTGGATGTCCTTCATGCCCTGAAAGTCGTTCGCTTTGTTAGTGA
TGCCACACCTCAGGCTGAAGTCTATCTCCGCATGTATCAGCTGGAGTCTGGGAAGTTACCTCGAAGTCCCTCTTTTCCACTGGAGCCAGA
TGATGAAGTGTTTCTTGCCATAGCTAAAGCCATGGAGGAAATGGTGGAAGATAGTGTCGACTGTTACTGGATCACCCGACGCTTTGTGAA
CCAATTAAATACCAAGTACCGGGATTCCTTGCCCCAGTTGCCAAAAGCGTTTGAACAATACTTGAATCTGGAAGATGGCAGACTGCTGAC
TCATCTGAGGATGTGTTCCGCGGCGCCCAAACTTCCTTATGATCTCTGGTTCAAGAGGTGCTTTGCGGGATGTTTGCCTGAATCCAGTTT
ACAGAGGGTTTGGGATAAAGTTGTGAGTGGATCCTGTAAGATCCTAGTTTTTGTAGCTGTCGAAATTTTATTAACCTTTAAAATAAAAGT
TATGGCACTGAACAGTGCAGAGAAGATAACAAAGTTTCTGGAAAATATTCCCCAGGACAGCTCAGACGCGATCGTGAGCAAGGCCATTGA
CTTGTGGCACAAACACTGTGGGACCCCGGTCCATTCAAGCTGAACGCACCCGCTGGTTGTGGACCGTCTGCCAGGCACCACAGTGAGCAT
TGTGTTCTTGGCATGTGATCTGGGAAACTGATTGAATAATACACTTTTCTTGCTTTGGTGCTCAAAGTGGTTTTTTTCCCCCAATAAAAT

>66609_66609_9_PMEL-TBC1D7_PMEL_chr12_56359720_ENST00000536427_TBC1D7_chr6_13321327_ENST00000379307_length(amino acids)=276AA_BP=47
MIPPQGPIPVPPVPLVAGGKNTMDLVLKRCLLHLAVIGALLAVGATKGILPPHHESHAKVMMYRKEQYLDVLHALKVVRFVSDATPQAEV
YLRMYQLESGKLPRSPSFPLEPDDEVFLAIAKAMEEMVEDSVDCYWITRRFVNQLNTKYRDSLPQLPKAFEQYLNLEDGRLLTHLRMCSA
APKLPYDLWFKRCFAGCLPESSLQRVWDKVVSGSCKILVFVAVEILLTFKIKVMALNSAEKITKFLENIPQDSSDAIVSKAIDLWHKHCG

--------------------------------------------------------------
>66609_66609_10_PMEL-TBC1D7_PMEL_chr12_56359720_ENST00000536427_TBC1D7_chr6_13321327_ENST00000607658_length(transcript)=1550nt_BP=164nt
AGCCCAGCGCTCCTCCCCGCAAATGATCCCGCCCCAGGGGCCTATCCCAGTCCCCCCAGTGCCTTTGGTTGCTGGAGGGAAGAACACAAT
GGATCTGGTGCTAAAAAGATGCCTTCTTCATTTGGCTGTGATAGGTGCTTTGCTGGCTGTGGGGGCTACAAAAGGAATCTTGCCTCCACA
CCACGAGTCCCATGCCAAGGTGATGATGTATCGTAAGGAGCAGTACTTGGATGTCCTTCATGCCCTGAAAGTCGTTCGCTTTGTTAGTGA
TGCCACACCTCAGGCTGAAGTCTATCTCCGCATGTATCAGCTGGAGTCTGGGAAGTTACCTCGAAGTCCCTCTTTTCCACTGGAGCCAGA
TGATGAAGTGTTTCTTGCCATAGCTAAAGCCATGGAGGAAATGGTGGAAGATAGTGTCGACTGTTACTGGATCACCCGACGCTTTGTGAA
CCAATTAAATACCAAGTACCGGGATTCCTTGCCCCAGTTGCCAAAAGCGTTTGAACAATACTTGAATCTGGAAGATGGCAGACTGCTGAC
TCATCTGAGGATGTGTTCCGCGGCGCCCAAACTTCCTTATGATCTCTGGTTCAAGAGGTGCTTTGCGGGATGTTTGCCTGAATCCAGTTT
ACAGAGGCAAGGTTTGGGATAAAGTTGTGAGTGGATCCTGTAAGATCCTAGTTTTTGTAGCTGTCGAAATTTTATTAACCTTTAAAATAA
AAGTTATGGCACTGAACAGTGCAGAGAAGATAACAAAGTTTCTGGAAAATGTAAGTGTGCTTTGATTTGATTTTGAATCTGGAAATGAAG
TTACCTTAGCAAGTCAGATTTTCCTGTTACATTAGATTATTTCAGAGAAATAATTACATGATTTTAGAGAAATAATACCTTAGAATGTTT
CAGAGAATAATTATAATAATGATTATTTTAGGGAAATTATTTAAGAGAAATAATAATTTGATTTGATTTTGAATCTAGAAATGAAGTCAC
TTTAGCAAGTGAGATTTTCCTGTTACATTAGATTATTTCAGAGAAATCATACAGTGTATTTTTACATTATAAGAAACACTTTTCCCTGAA
AAAGTTTGGCCTAAAGTTGGCCTGAGGGTTAGTTTGCATCCTGTCTTTGGGAAATGATGGTCTGAGACCATCTCGTGAATGTGTCCACTT
AGAACCAGAGTCTCATCCTCCATGTGACTATCAGCAGGCATGTCAGGAAAAGGAATAGGTGGGATCTGTCATTTTACAATGAGTAATTTT
TGTCAGTTCAAAAGGGGTTCTGTATTTTGGAGGATTTTGTAAGCCATTTCATTTCTGTTACTGTCTCTGGTGTAGTCCCAGTTGGGTTTA
TTAATATACAGTATTAACCTAGTATATTGCTGAAAAAGGCAATGGTAATGAAATTAACTTTTCCCTCGCTATGTATCTTGGAATACCCTT
TACCAGGCAAGAAGTAGGATTAAAGAGACTTATGCCTGAATGATTTTCACAGAATCCAAAATCTATTCATTTTTAAAATAGTATTAACAT

>66609_66609_10_PMEL-TBC1D7_PMEL_chr12_56359720_ENST00000536427_TBC1D7_chr6_13321327_ENST00000607658_length(amino acids)=209AA_BP=47
MIPPQGPIPVPPVPLVAGGKNTMDLVLKRCLLHLAVIGALLAVGATKGILPPHHESHAKVMMYRKEQYLDVLHALKVVRFVSDATPQAEV
YLRMYQLESGKLPRSPSFPLEPDDEVFLAIAKAMEEMVEDSVDCYWITRRFVNQLNTKYRDSLPQLPKAFEQYLNLEDGRLLTHLRMCSA

--------------------------------------------------------------
>66609_66609_11_PMEL-TBC1D7_PMEL_chr12_56359720_ENST00000539511_TBC1D7_chr6_13321327_ENST00000343141_length(transcript)=739nt_BP=164nt
AGCCCAGCGCTCCTCCCCGCAAATGATCCCGCCCCAGGGGCCTATCCCAGTCCCCCCAGTGCCTTTGGTTGCTGGAGGGAAGAACACAAT
GGATCTGGTGCTAAAAAGATGCCTTCTTCATTTGGCTGTGATAGGTGCTTTGCTGGCTGTGGGGGCTACAAAAGGAATCTTGCCTCCACA
CCACGAGTCCCATGCCAAGGTGATGATGTATCGTAAGGAGCAGTACTTGGATGTCCTTCATGCCCTGAAAGTCGTTCGCTTTGTTAGTGA
TGCCACACCTCAGGCTGAAGTCTATCTCCGCATGTATCAGCTGGAGTCTGGGAAGTTACCTCGAAGTCCCTCTTTTCCACTGCCAAAAGC
GTTTGAACAATACTTGAATCTGGAAGATGGCAGACTGCTGACTCATCTGAGGATGTGTTCCGCGGCGCCCAAACTTCCTTATGATCTCTG
GTTCAAGAGGTGCTTTGCGGGATGTTTGCCTGAATCCAGTTTACAGAGGGTTTGGGATAAAGTTGTGAGTGGATCCTGTAAGATCCTAGT
TTTTGTAGCTGTCGAAATTTTATTAACCTTTAAAATAAAAGTTATGGCACTGAACAGTGCAGAGAAGATAACAAAGTTTCTGGAAAATAT
TCCCCAGGACAGCTCAGACGCGATCGTGAGCAAGGCCATTGACTTGTGGCACAAACACTGTGGGACCCCGGTCCATTCAAGCTGAACGCA

>66609_66609_11_PMEL-TBC1D7_PMEL_chr12_56359720_ENST00000539511_TBC1D7_chr6_13321327_ENST00000343141_length(amino acids)=230AA_BP=47
MIPPQGPIPVPPVPLVAGGKNTMDLVLKRCLLHLAVIGALLAVGATKGILPPHHESHAKVMMYRKEQYLDVLHALKVVRFVSDATPQAEV
YLRMYQLESGKLPRSPSFPLPKAFEQYLNLEDGRLLTHLRMCSAAPKLPYDLWFKRCFAGCLPESSLQRVWDKVVSGSCKILVFVAVEIL

--------------------------------------------------------------
>66609_66609_12_PMEL-TBC1D7_PMEL_chr12_56359720_ENST00000539511_TBC1D7_chr6_13321327_ENST00000356436_length(transcript)=1003nt_BP=164nt
AGCCCAGCGCTCCTCCCCGCAAATGATCCCGCCCCAGGGGCCTATCCCAGTCCCCCCAGTGCCTTTGGTTGCTGGAGGGAAGAACACAAT
GGATCTGGTGCTAAAAAGATGCCTTCTTCATTTGGCTGTGATAGGTGCTTTGCTGGCTGTGGGGGCTACAAAAGGAATCTTGCCTCCACA
CCACGAGTCCCATGCCAAGGTGATGATGTATCGTAAGGAGCAGTACTTGGATGTCCTTCATGCCCTGAAAGTCGTTCGCTTTGTTAGTGA
TGCCACACCTCAGGCTGAAGTCTATCTCCGCATGTATCAGCTGGAGTCTGGGAAGTTACCTCGAAGTCCCTCTTTTCCACTGGAGCCAGA
TGATGAAGTGTTTCTTGCCATAGCTAAAGCCATGGAGGAAATGGTGGAAGATAGTGTCGACTGTTACTGGATCACCCGACGCTTTGTGAA
CCAATTAAATACCAAGTACCGGGATTCCTTGCCCCAGTTGCCAAAAGCGTTTGAACAATACTTGAATCTGGAAGATGGCAGACTGCTGAC
TCATCTGAGGATGTGTTCCGCGGCGCCCAAACTTCCTTATGATCTCTGGTTCAAGAGGTGCTTTGCGGGATGTTTGCCTGAATCCAGTTT
ACAGAGGGTTTGGGATAAAGTTGTGAGTGGATCCTGTAAGATCCTAGTTTTTGTAGCTGTCGAAATTTTATTAACCTTTAAAATAAAAGT
TATGGCACTGAACAGTGCAGAGAAGATAACAAAGTTTCTGGAAAATATTCCCCAGGACAGCTCAGACGCGATCGTGAGCAAGGCCATTGA
CTTGTGGCACAAACACTGTGGGACCCCGGTCCATTCAAGCTGAACGCACCCGCTGGTTGTGGACCGTCTGCCAGGCACCACAGTGAGCAT
TGTGTTCTTGGCATGTGATCTGGGAAACTGATTGAATAATACACTTTTCTTGCTTTGGTGCTCAAAGTGGTTTTTTTCCCCCAATAAAAT

>66609_66609_12_PMEL-TBC1D7_PMEL_chr12_56359720_ENST00000539511_TBC1D7_chr6_13321327_ENST00000356436_length(amino acids)=276AA_BP=47
MIPPQGPIPVPPVPLVAGGKNTMDLVLKRCLLHLAVIGALLAVGATKGILPPHHESHAKVMMYRKEQYLDVLHALKVVRFVSDATPQAEV
YLRMYQLESGKLPRSPSFPLEPDDEVFLAIAKAMEEMVEDSVDCYWITRRFVNQLNTKYRDSLPQLPKAFEQYLNLEDGRLLTHLRMCSA
APKLPYDLWFKRCFAGCLPESSLQRVWDKVVSGSCKILVFVAVEILLTFKIKVMALNSAEKITKFLENIPQDSSDAIVSKAIDLWHKHCG

--------------------------------------------------------------
>66609_66609_13_PMEL-TBC1D7_PMEL_chr12_56359720_ENST00000539511_TBC1D7_chr6_13321327_ENST00000379300_length(transcript)=1003nt_BP=164nt
AGCCCAGCGCTCCTCCCCGCAAATGATCCCGCCCCAGGGGCCTATCCCAGTCCCCCCAGTGCCTTTGGTTGCTGGAGGGAAGAACACAAT
GGATCTGGTGCTAAAAAGATGCCTTCTTCATTTGGCTGTGATAGGTGCTTTGCTGGCTGTGGGGGCTACAAAAGGAATCTTGCCTCCACA
CCACGAGTCCCATGCCAAGGTGATGATGTATCGTAAGGAGCAGTACTTGGATGTCCTTCATGCCCTGAAAGTCGTTCGCTTTGTTAGTGA
TGCCACACCTCAGGCTGAAGTCTATCTCCGCATGTATCAGCTGGAGTCTGGGAAGTTACCTCGAAGTCCCTCTTTTCCACTGGAGCCAGA
TGATGAAGTGTTTCTTGCCATAGCTAAAGCCATGGAGGAAATGGTGGAAGATAGTGTCGACTGTTACTGGATCACCCGACGCTTTGTGAA
CCAATTAAATACCAAGTACCGGGATTCCTTGCCCCAGTTGCCAAAAGCGTTTGAACAATACTTGAATCTGGAAGATGGCAGACTGCTGAC
TCATCTGAGGATGTGTTCCGCGGCGCCCAAACTTCCTTATGATCTCTGGTTCAAGAGGTGCTTTGCGGGATGTTTGCCTGAATCCAGTTT
ACAGAGGGTTTGGGATAAAGTTGTGAGTGGATCCTGTAAGATCCTAGTTTTTGTAGCTGTCGAAATTTTATTAACCTTTAAAATAAAAGT
TATGGCACTGAACAGTGCAGAGAAGATAACAAAGTTTCTGGAAAATATTCCCCAGGACAGCTCAGACGCGATCGTGAGCAAGGCCATTGA
CTTGTGGCACAAACACTGTGGGACCCCGGTCCATTCAAGCTGAACGCACCCGCTGGTTGTGGACCGTCTGCCAGGCACCACAGTGAGCAT
TGTGTTCTTGGCATGTGATCTGGGAAACTGATTGAATAATACACTTTTCTTGCTTTGGTGCTCAAAGTGGTTTTTTTCCCCCAATAAAAT

>66609_66609_13_PMEL-TBC1D7_PMEL_chr12_56359720_ENST00000539511_TBC1D7_chr6_13321327_ENST00000379300_length(amino acids)=276AA_BP=47
MIPPQGPIPVPPVPLVAGGKNTMDLVLKRCLLHLAVIGALLAVGATKGILPPHHESHAKVMMYRKEQYLDVLHALKVVRFVSDATPQAEV
YLRMYQLESGKLPRSPSFPLEPDDEVFLAIAKAMEEMVEDSVDCYWITRRFVNQLNTKYRDSLPQLPKAFEQYLNLEDGRLLTHLRMCSA
APKLPYDLWFKRCFAGCLPESSLQRVWDKVVSGSCKILVFVAVEILLTFKIKVMALNSAEKITKFLENIPQDSSDAIVSKAIDLWHKHCG

--------------------------------------------------------------
>66609_66609_14_PMEL-TBC1D7_PMEL_chr12_56359720_ENST00000539511_TBC1D7_chr6_13321327_ENST00000379307_length(transcript)=1000nt_BP=164nt
AGCCCAGCGCTCCTCCCCGCAAATGATCCCGCCCCAGGGGCCTATCCCAGTCCCCCCAGTGCCTTTGGTTGCTGGAGGGAAGAACACAAT
GGATCTGGTGCTAAAAAGATGCCTTCTTCATTTGGCTGTGATAGGTGCTTTGCTGGCTGTGGGGGCTACAAAAGGAATCTTGCCTCCACA
CCACGAGTCCCATGCCAAGGTGATGATGTATCGTAAGGAGCAGTACTTGGATGTCCTTCATGCCCTGAAAGTCGTTCGCTTTGTTAGTGA
TGCCACACCTCAGGCTGAAGTCTATCTCCGCATGTATCAGCTGGAGTCTGGGAAGTTACCTCGAAGTCCCTCTTTTCCACTGGAGCCAGA
TGATGAAGTGTTTCTTGCCATAGCTAAAGCCATGGAGGAAATGGTGGAAGATAGTGTCGACTGTTACTGGATCACCCGACGCTTTGTGAA
CCAATTAAATACCAAGTACCGGGATTCCTTGCCCCAGTTGCCAAAAGCGTTTGAACAATACTTGAATCTGGAAGATGGCAGACTGCTGAC
TCATCTGAGGATGTGTTCCGCGGCGCCCAAACTTCCTTATGATCTCTGGTTCAAGAGGTGCTTTGCGGGATGTTTGCCTGAATCCAGTTT
ACAGAGGGTTTGGGATAAAGTTGTGAGTGGATCCTGTAAGATCCTAGTTTTTGTAGCTGTCGAAATTTTATTAACCTTTAAAATAAAAGT
TATGGCACTGAACAGTGCAGAGAAGATAACAAAGTTTCTGGAAAATATTCCCCAGGACAGCTCAGACGCGATCGTGAGCAAGGCCATTGA
CTTGTGGCACAAACACTGTGGGACCCCGGTCCATTCAAGCTGAACGCACCCGCTGGTTGTGGACCGTCTGCCAGGCACCACAGTGAGCAT
TGTGTTCTTGGCATGTGATCTGGGAAACTGATTGAATAATACACTTTTCTTGCTTTGGTGCTCAAAGTGGTTTTTTTCCCCCAATAAAAT

>66609_66609_14_PMEL-TBC1D7_PMEL_chr12_56359720_ENST00000539511_TBC1D7_chr6_13321327_ENST00000379307_length(amino acids)=276AA_BP=47
MIPPQGPIPVPPVPLVAGGKNTMDLVLKRCLLHLAVIGALLAVGATKGILPPHHESHAKVMMYRKEQYLDVLHALKVVRFVSDATPQAEV
YLRMYQLESGKLPRSPSFPLEPDDEVFLAIAKAMEEMVEDSVDCYWITRRFVNQLNTKYRDSLPQLPKAFEQYLNLEDGRLLTHLRMCSA
APKLPYDLWFKRCFAGCLPESSLQRVWDKVVSGSCKILVFVAVEILLTFKIKVMALNSAEKITKFLENIPQDSSDAIVSKAIDLWHKHCG

--------------------------------------------------------------
>66609_66609_15_PMEL-TBC1D7_PMEL_chr12_56359720_ENST00000539511_TBC1D7_chr6_13321327_ENST00000607658_length(transcript)=1550nt_BP=164nt
AGCCCAGCGCTCCTCCCCGCAAATGATCCCGCCCCAGGGGCCTATCCCAGTCCCCCCAGTGCCTTTGGTTGCTGGAGGGAAGAACACAAT
GGATCTGGTGCTAAAAAGATGCCTTCTTCATTTGGCTGTGATAGGTGCTTTGCTGGCTGTGGGGGCTACAAAAGGAATCTTGCCTCCACA
CCACGAGTCCCATGCCAAGGTGATGATGTATCGTAAGGAGCAGTACTTGGATGTCCTTCATGCCCTGAAAGTCGTTCGCTTTGTTAGTGA
TGCCACACCTCAGGCTGAAGTCTATCTCCGCATGTATCAGCTGGAGTCTGGGAAGTTACCTCGAAGTCCCTCTTTTCCACTGGAGCCAGA
TGATGAAGTGTTTCTTGCCATAGCTAAAGCCATGGAGGAAATGGTGGAAGATAGTGTCGACTGTTACTGGATCACCCGACGCTTTGTGAA
CCAATTAAATACCAAGTACCGGGATTCCTTGCCCCAGTTGCCAAAAGCGTTTGAACAATACTTGAATCTGGAAGATGGCAGACTGCTGAC
TCATCTGAGGATGTGTTCCGCGGCGCCCAAACTTCCTTATGATCTCTGGTTCAAGAGGTGCTTTGCGGGATGTTTGCCTGAATCCAGTTT
ACAGAGGCAAGGTTTGGGATAAAGTTGTGAGTGGATCCTGTAAGATCCTAGTTTTTGTAGCTGTCGAAATTTTATTAACCTTTAAAATAA
AAGTTATGGCACTGAACAGTGCAGAGAAGATAACAAAGTTTCTGGAAAATGTAAGTGTGCTTTGATTTGATTTTGAATCTGGAAATGAAG
TTACCTTAGCAAGTCAGATTTTCCTGTTACATTAGATTATTTCAGAGAAATAATTACATGATTTTAGAGAAATAATACCTTAGAATGTTT
CAGAGAATAATTATAATAATGATTATTTTAGGGAAATTATTTAAGAGAAATAATAATTTGATTTGATTTTGAATCTAGAAATGAAGTCAC
TTTAGCAAGTGAGATTTTCCTGTTACATTAGATTATTTCAGAGAAATCATACAGTGTATTTTTACATTATAAGAAACACTTTTCCCTGAA
AAAGTTTGGCCTAAAGTTGGCCTGAGGGTTAGTTTGCATCCTGTCTTTGGGAAATGATGGTCTGAGACCATCTCGTGAATGTGTCCACTT
AGAACCAGAGTCTCATCCTCCATGTGACTATCAGCAGGCATGTCAGGAAAAGGAATAGGTGGGATCTGTCATTTTACAATGAGTAATTTT
TGTCAGTTCAAAAGGGGTTCTGTATTTTGGAGGATTTTGTAAGCCATTTCATTTCTGTTACTGTCTCTGGTGTAGTCCCAGTTGGGTTTA
TTAATATACAGTATTAACCTAGTATATTGCTGAAAAAGGCAATGGTAATGAAATTAACTTTTCCCTCGCTATGTATCTTGGAATACCCTT
TACCAGGCAAGAAGTAGGATTAAAGAGACTTATGCCTGAATGATTTTCACAGAATCCAAAATCTATTCATTTTTAAAATAGTATTAACAT

>66609_66609_15_PMEL-TBC1D7_PMEL_chr12_56359720_ENST00000539511_TBC1D7_chr6_13321327_ENST00000607658_length(amino acids)=209AA_BP=47
MIPPQGPIPVPPVPLVAGGKNTMDLVLKRCLLHLAVIGALLAVGATKGILPPHHESHAKVMMYRKEQYLDVLHALKVVRFVSDATPQAEV
YLRMYQLESGKLPRSPSFPLEPDDEVFLAIAKAMEEMVEDSVDCYWITRRFVNQLNTKYRDSLPQLPKAFEQYLNLEDGRLLTHLRMCSA

--------------------------------------------------------------
>66609_66609_16_PMEL-TBC1D7_PMEL_chr12_56359720_ENST00000548493_TBC1D7_chr6_13321327_ENST00000343141_length(transcript)=761nt_BP=186nt
TCAACGTCAGAGCCGGGGGGCGAGCCCAGCGCTCCTCCCCGCAAATGATCCCGCCCCAGGGGCCTATCCCAGTCCCCCCAGTGCCTTTGG
TTGCTGGAGGGAAGAACACAATGGATCTGGTGCTAAAAAGATGCCTTCTTCATTTGGCTGTGATAGGTGCTTTGCTGGCTGTGGGGGCTA
CAAAAGGAATCTTGCCTCCACACCACGAGTCCCATGCCAAGGTGATGATGTATCGTAAGGAGCAGTACTTGGATGTCCTTCATGCCCTGA
AAGTCGTTCGCTTTGTTAGTGATGCCACACCTCAGGCTGAAGTCTATCTCCGCATGTATCAGCTGGAGTCTGGGAAGTTACCTCGAAGTC
CCTCTTTTCCACTGCCAAAAGCGTTTGAACAATACTTGAATCTGGAAGATGGCAGACTGCTGACTCATCTGAGGATGTGTTCCGCGGCGC
CCAAACTTCCTTATGATCTCTGGTTCAAGAGGTGCTTTGCGGGATGTTTGCCTGAATCCAGTTTACAGAGGGTTTGGGATAAAGTTGTGA
GTGGATCCTGTAAGATCCTAGTTTTTGTAGCTGTCGAAATTTTATTAACCTTTAAAATAAAAGTTATGGCACTGAACAGTGCAGAGAAGA
TAACAAAGTTTCTGGAAAATATTCCCCAGGACAGCTCAGACGCGATCGTGAGCAAGGCCATTGACTTGTGGCACAAACACTGTGGGACCC

>66609_66609_16_PMEL-TBC1D7_PMEL_chr12_56359720_ENST00000548493_TBC1D7_chr6_13321327_ENST00000343141_length(amino acids)=230AA_BP=47
MIPPQGPIPVPPVPLVAGGKNTMDLVLKRCLLHLAVIGALLAVGATKGILPPHHESHAKVMMYRKEQYLDVLHALKVVRFVSDATPQAEV
YLRMYQLESGKLPRSPSFPLPKAFEQYLNLEDGRLLTHLRMCSAAPKLPYDLWFKRCFAGCLPESSLQRVWDKVVSGSCKILVFVAVEIL

--------------------------------------------------------------
>66609_66609_17_PMEL-TBC1D7_PMEL_chr12_56359720_ENST00000548493_TBC1D7_chr6_13321327_ENST00000356436_length(transcript)=1025nt_BP=186nt
TCAACGTCAGAGCCGGGGGGCGAGCCCAGCGCTCCTCCCCGCAAATGATCCCGCCCCAGGGGCCTATCCCAGTCCCCCCAGTGCCTTTGG
TTGCTGGAGGGAAGAACACAATGGATCTGGTGCTAAAAAGATGCCTTCTTCATTTGGCTGTGATAGGTGCTTTGCTGGCTGTGGGGGCTA
CAAAAGGAATCTTGCCTCCACACCACGAGTCCCATGCCAAGGTGATGATGTATCGTAAGGAGCAGTACTTGGATGTCCTTCATGCCCTGA
AAGTCGTTCGCTTTGTTAGTGATGCCACACCTCAGGCTGAAGTCTATCTCCGCATGTATCAGCTGGAGTCTGGGAAGTTACCTCGAAGTC
CCTCTTTTCCACTGGAGCCAGATGATGAAGTGTTTCTTGCCATAGCTAAAGCCATGGAGGAAATGGTGGAAGATAGTGTCGACTGTTACT
GGATCACCCGACGCTTTGTGAACCAATTAAATACCAAGTACCGGGATTCCTTGCCCCAGTTGCCAAAAGCGTTTGAACAATACTTGAATC
TGGAAGATGGCAGACTGCTGACTCATCTGAGGATGTGTTCCGCGGCGCCCAAACTTCCTTATGATCTCTGGTTCAAGAGGTGCTTTGCGG
GATGTTTGCCTGAATCCAGTTTACAGAGGGTTTGGGATAAAGTTGTGAGTGGATCCTGTAAGATCCTAGTTTTTGTAGCTGTCGAAATTT
TATTAACCTTTAAAATAAAAGTTATGGCACTGAACAGTGCAGAGAAGATAACAAAGTTTCTGGAAAATATTCCCCAGGACAGCTCAGACG
CGATCGTGAGCAAGGCCATTGACTTGTGGCACAAACACTGTGGGACCCCGGTCCATTCAAGCTGAACGCACCCGCTGGTTGTGGACCGTC
TGCCAGGCACCACAGTGAGCATTGTGTTCTTGGCATGTGATCTGGGAAACTGATTGAATAATACACTTTTCTTGCTTTGGTGCTCAAAGT

>66609_66609_17_PMEL-TBC1D7_PMEL_chr12_56359720_ENST00000548493_TBC1D7_chr6_13321327_ENST00000356436_length(amino acids)=276AA_BP=47
MIPPQGPIPVPPVPLVAGGKNTMDLVLKRCLLHLAVIGALLAVGATKGILPPHHESHAKVMMYRKEQYLDVLHALKVVRFVSDATPQAEV
YLRMYQLESGKLPRSPSFPLEPDDEVFLAIAKAMEEMVEDSVDCYWITRRFVNQLNTKYRDSLPQLPKAFEQYLNLEDGRLLTHLRMCSA
APKLPYDLWFKRCFAGCLPESSLQRVWDKVVSGSCKILVFVAVEILLTFKIKVMALNSAEKITKFLENIPQDSSDAIVSKAIDLWHKHCG

--------------------------------------------------------------
>66609_66609_18_PMEL-TBC1D7_PMEL_chr12_56359720_ENST00000548493_TBC1D7_chr6_13321327_ENST00000379300_length(transcript)=1025nt_BP=186nt
TCAACGTCAGAGCCGGGGGGCGAGCCCAGCGCTCCTCCCCGCAAATGATCCCGCCCCAGGGGCCTATCCCAGTCCCCCCAGTGCCTTTGG
TTGCTGGAGGGAAGAACACAATGGATCTGGTGCTAAAAAGATGCCTTCTTCATTTGGCTGTGATAGGTGCTTTGCTGGCTGTGGGGGCTA
CAAAAGGAATCTTGCCTCCACACCACGAGTCCCATGCCAAGGTGATGATGTATCGTAAGGAGCAGTACTTGGATGTCCTTCATGCCCTGA
AAGTCGTTCGCTTTGTTAGTGATGCCACACCTCAGGCTGAAGTCTATCTCCGCATGTATCAGCTGGAGTCTGGGAAGTTACCTCGAAGTC
CCTCTTTTCCACTGGAGCCAGATGATGAAGTGTTTCTTGCCATAGCTAAAGCCATGGAGGAAATGGTGGAAGATAGTGTCGACTGTTACT
GGATCACCCGACGCTTTGTGAACCAATTAAATACCAAGTACCGGGATTCCTTGCCCCAGTTGCCAAAAGCGTTTGAACAATACTTGAATC
TGGAAGATGGCAGACTGCTGACTCATCTGAGGATGTGTTCCGCGGCGCCCAAACTTCCTTATGATCTCTGGTTCAAGAGGTGCTTTGCGG
GATGTTTGCCTGAATCCAGTTTACAGAGGGTTTGGGATAAAGTTGTGAGTGGATCCTGTAAGATCCTAGTTTTTGTAGCTGTCGAAATTT
TATTAACCTTTAAAATAAAAGTTATGGCACTGAACAGTGCAGAGAAGATAACAAAGTTTCTGGAAAATATTCCCCAGGACAGCTCAGACG
CGATCGTGAGCAAGGCCATTGACTTGTGGCACAAACACTGTGGGACCCCGGTCCATTCAAGCTGAACGCACCCGCTGGTTGTGGACCGTC
TGCCAGGCACCACAGTGAGCATTGTGTTCTTGGCATGTGATCTGGGAAACTGATTGAATAATACACTTTTCTTGCTTTGGTGCTCAAAGT

>66609_66609_18_PMEL-TBC1D7_PMEL_chr12_56359720_ENST00000548493_TBC1D7_chr6_13321327_ENST00000379300_length(amino acids)=276AA_BP=47
MIPPQGPIPVPPVPLVAGGKNTMDLVLKRCLLHLAVIGALLAVGATKGILPPHHESHAKVMMYRKEQYLDVLHALKVVRFVSDATPQAEV
YLRMYQLESGKLPRSPSFPLEPDDEVFLAIAKAMEEMVEDSVDCYWITRRFVNQLNTKYRDSLPQLPKAFEQYLNLEDGRLLTHLRMCSA
APKLPYDLWFKRCFAGCLPESSLQRVWDKVVSGSCKILVFVAVEILLTFKIKVMALNSAEKITKFLENIPQDSSDAIVSKAIDLWHKHCG

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>66609_66609_19_PMEL-TBC1D7_PMEL_chr12_56359720_ENST00000548493_TBC1D7_chr6_13321327_ENST00000379307_length(transcript)=1022nt_BP=186nt
TCAACGTCAGAGCCGGGGGGCGAGCCCAGCGCTCCTCCCCGCAAATGATCCCGCCCCAGGGGCCTATCCCAGTCCCCCCAGTGCCTTTGG
TTGCTGGAGGGAAGAACACAATGGATCTGGTGCTAAAAAGATGCCTTCTTCATTTGGCTGTGATAGGTGCTTTGCTGGCTGTGGGGGCTA
CAAAAGGAATCTTGCCTCCACACCACGAGTCCCATGCCAAGGTGATGATGTATCGTAAGGAGCAGTACTTGGATGTCCTTCATGCCCTGA
AAGTCGTTCGCTTTGTTAGTGATGCCACACCTCAGGCTGAAGTCTATCTCCGCATGTATCAGCTGGAGTCTGGGAAGTTACCTCGAAGTC
CCTCTTTTCCACTGGAGCCAGATGATGAAGTGTTTCTTGCCATAGCTAAAGCCATGGAGGAAATGGTGGAAGATAGTGTCGACTGTTACT
GGATCACCCGACGCTTTGTGAACCAATTAAATACCAAGTACCGGGATTCCTTGCCCCAGTTGCCAAAAGCGTTTGAACAATACTTGAATC
TGGAAGATGGCAGACTGCTGACTCATCTGAGGATGTGTTCCGCGGCGCCCAAACTTCCTTATGATCTCTGGTTCAAGAGGTGCTTTGCGG
GATGTTTGCCTGAATCCAGTTTACAGAGGGTTTGGGATAAAGTTGTGAGTGGATCCTGTAAGATCCTAGTTTTTGTAGCTGTCGAAATTT
TATTAACCTTTAAAATAAAAGTTATGGCACTGAACAGTGCAGAGAAGATAACAAAGTTTCTGGAAAATATTCCCCAGGACAGCTCAGACG
CGATCGTGAGCAAGGCCATTGACTTGTGGCACAAACACTGTGGGACCCCGGTCCATTCAAGCTGAACGCACCCGCTGGTTGTGGACCGTC
TGCCAGGCACCACAGTGAGCATTGTGTTCTTGGCATGTGATCTGGGAAACTGATTGAATAATACACTTTTCTTGCTTTGGTGCTCAAAGT

>66609_66609_19_PMEL-TBC1D7_PMEL_chr12_56359720_ENST00000548493_TBC1D7_chr6_13321327_ENST00000379307_length(amino acids)=276AA_BP=47
MIPPQGPIPVPPVPLVAGGKNTMDLVLKRCLLHLAVIGALLAVGATKGILPPHHESHAKVMMYRKEQYLDVLHALKVVRFVSDATPQAEV
YLRMYQLESGKLPRSPSFPLEPDDEVFLAIAKAMEEMVEDSVDCYWITRRFVNQLNTKYRDSLPQLPKAFEQYLNLEDGRLLTHLRMCSA
APKLPYDLWFKRCFAGCLPESSLQRVWDKVVSGSCKILVFVAVEILLTFKIKVMALNSAEKITKFLENIPQDSSDAIVSKAIDLWHKHCG

--------------------------------------------------------------
>66609_66609_20_PMEL-TBC1D7_PMEL_chr12_56359720_ENST00000548493_TBC1D7_chr6_13321327_ENST00000607658_length(transcript)=1572nt_BP=186nt
TCAACGTCAGAGCCGGGGGGCGAGCCCAGCGCTCCTCCCCGCAAATGATCCCGCCCCAGGGGCCTATCCCAGTCCCCCCAGTGCCTTTGG
TTGCTGGAGGGAAGAACACAATGGATCTGGTGCTAAAAAGATGCCTTCTTCATTTGGCTGTGATAGGTGCTTTGCTGGCTGTGGGGGCTA
CAAAAGGAATCTTGCCTCCACACCACGAGTCCCATGCCAAGGTGATGATGTATCGTAAGGAGCAGTACTTGGATGTCCTTCATGCCCTGA
AAGTCGTTCGCTTTGTTAGTGATGCCACACCTCAGGCTGAAGTCTATCTCCGCATGTATCAGCTGGAGTCTGGGAAGTTACCTCGAAGTC
CCTCTTTTCCACTGGAGCCAGATGATGAAGTGTTTCTTGCCATAGCTAAAGCCATGGAGGAAATGGTGGAAGATAGTGTCGACTGTTACT
GGATCACCCGACGCTTTGTGAACCAATTAAATACCAAGTACCGGGATTCCTTGCCCCAGTTGCCAAAAGCGTTTGAACAATACTTGAATC
TGGAAGATGGCAGACTGCTGACTCATCTGAGGATGTGTTCCGCGGCGCCCAAACTTCCTTATGATCTCTGGTTCAAGAGGTGCTTTGCGG
GATGTTTGCCTGAATCCAGTTTACAGAGGCAAGGTTTGGGATAAAGTTGTGAGTGGATCCTGTAAGATCCTAGTTTTTGTAGCTGTCGAA
ATTTTATTAACCTTTAAAATAAAAGTTATGGCACTGAACAGTGCAGAGAAGATAACAAAGTTTCTGGAAAATGTAAGTGTGCTTTGATTT
GATTTTGAATCTGGAAATGAAGTTACCTTAGCAAGTCAGATTTTCCTGTTACATTAGATTATTTCAGAGAAATAATTACATGATTTTAGA
GAAATAATACCTTAGAATGTTTCAGAGAATAATTATAATAATGATTATTTTAGGGAAATTATTTAAGAGAAATAATAATTTGATTTGATT
TTGAATCTAGAAATGAAGTCACTTTAGCAAGTGAGATTTTCCTGTTACATTAGATTATTTCAGAGAAATCATACAGTGTATTTTTACATT
ATAAGAAACACTTTTCCCTGAAAAAGTTTGGCCTAAAGTTGGCCTGAGGGTTAGTTTGCATCCTGTCTTTGGGAAATGATGGTCTGAGAC
CATCTCGTGAATGTGTCCACTTAGAACCAGAGTCTCATCCTCCATGTGACTATCAGCAGGCATGTCAGGAAAAGGAATAGGTGGGATCTG
TCATTTTACAATGAGTAATTTTTGTCAGTTCAAAAGGGGTTCTGTATTTTGGAGGATTTTGTAAGCCATTTCATTTCTGTTACTGTCTCT
GGTGTAGTCCCAGTTGGGTTTATTAATATACAGTATTAACCTAGTATATTGCTGAAAAAGGCAATGGTAATGAAATTAACTTTTCCCTCG
CTATGTATCTTGGAATACCCTTTACCAGGCAAGAAGTAGGATTAAAGAGACTTATGCCTGAATGATTTTCACAGAATCCAAAATCTATTC

>66609_66609_20_PMEL-TBC1D7_PMEL_chr12_56359720_ENST00000548493_TBC1D7_chr6_13321327_ENST00000607658_length(amino acids)=209AA_BP=47
MIPPQGPIPVPPVPLVAGGKNTMDLVLKRCLLHLAVIGALLAVGATKGILPPHHESHAKVMMYRKEQYLDVLHALKVVRFVSDATPQAEV
YLRMYQLESGKLPRSPSFPLEPDDEVFLAIAKAMEEMVEDSVDCYWITRRFVNQLNTKYRDSLPQLPKAFEQYLNLEDGRLLTHLRMCSA

--------------------------------------------------------------

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Fusion Gene PPI Analysis for PMEL-TBC1D7


check button Go to ChiPPI (Chimeric Protein-Protein interactions) to see the chimeric PPI interaction in

ChiPPI page.


check button Protein-protein interactors with each fusion partner protein in wild-type (BIOGRID-3.4.160)
HgeneHgene's interactorsTgeneTgene's interactors


check button - Retained PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenStill interaction with


check button - Lost PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


check button - Retained PPIs, but lost function due to frame-shift fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


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Related Drugs for PMEL-TBC1D7


check button Drugs targeting genes involved in this fusion gene.
(DrugBank Version 5.1.8 2021-05-08)
PartnerGeneUniProtAccDrugBank IDDrug nameDrug activityDrug typeDrug status

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Related Diseases for PMEL-TBC1D7


check button Diseases associated with fusion partners.
(DisGeNet 4.0)
PartnerGeneDisease IDDisease name# pubmedsSource