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Center for Computational Systems Medicine
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Fusion Gene Summary

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Fusion Gene ORF analysis

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Fusion Genomic Features

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Fusion Protein Features

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Fusion Gene Sequence

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Fusion Gene PPI analysis

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Fusion gene:PMM2-RBFOX1 (FusionGDB2 ID:66648)

Fusion Gene Summary for PMM2-RBFOX1

check button Fusion gene summary
Fusion gene informationFusion gene name: PMM2-RBFOX1
Fusion gene ID: 66648
HgeneTgene
Gene symbol

PMM2

RBFOX1

Gene ID

5373

54715

Gene namephosphomannomutase 2RNA binding fox-1 homolog 1
SynonymsCDG1|CDG1a|CDGS|PMI|PMI1|PMM 22BP1|A2BP1|FOX-1|FOX1|HRNBP1
Cytomap

16p13.2

16p13.3

Type of geneprotein-codingprotein-coding
Descriptionphosphomannomutase 2mannose-6-phosphate isomerasephosphomannose isomerase 1RNA binding protein fox-1 homolog 1RNA binding protein, fox-1 homolog 1ataxin 2-binding protein 1fox-1 homolog Afox-1-like RNA-binding protein 1hexaribonucleotide binding protein 1 isoform alphahexaribonucleotide binding protein 1 isoform betahexar
Modification date2020031320200313
UniProtAcc..
Ensembl transtripts involved in fusion geneENST00000268261, ENST00000537352, 
ENST00000539622, ENST00000566983, 
ENST00000569958, ENST00000565837, 
ENST00000311745, ENST00000340209, 
ENST00000355637, ENST00000436368, 
ENST00000547338, ENST00000547427, 
ENST00000552089, ENST00000422070, 
ENST00000535565, ENST00000547372, 
ENST00000550418, ENST00000553186, 
Fusion gene scores* DoF score7 X 4 X 4=11236 X 34 X 8=9792
# samples 739
** MAII scorelog2(7/112*10)=-0.678071905112638
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0		log2(39/9792*10)=-4.65005752894304
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0
Context

PubMed: PMM2 [Title/Abstract] AND RBFOX1 [Title/Abstract] AND fusion [Title/Abstract]

Most frequent breakpointPMM2(8906963)-RBFOX1(7568149), # samples:1
Anticipated loss of major functional domain due to fusion event.
* DoF score (Degree of Frequency) = # partners X # break points X # cancer types
** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10)

check button Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez
PartnerGeneGO IDGO termPubMed ID

check buttonFusion gene breakpoints across PMM2 (5'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.
all structure

check buttonFusion gene breakpoints across RBFOX1 (3'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.
all structure

check button Fusion gene information from two resources (ChiTars 5.0 and ChimerDB 4.0)
* All genome coordinats were lifted-over on hg19.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
SourceDiseaseSampleHgeneHchrHbpHstrandTgeneTchrTbpTstrand
ChimerDB4STADTCGA-HU-A4HB-01APMM2chr16

8906963

+RBFOX1chr16

7568149

+


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Fusion Gene ORF analysis for PMM2-RBFOX1

check button Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
ORFHenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrand
5CDS-intronENST00000268261ENST00000311745PMM2chr16

8906963

+RBFOX1chr16

7568149

+
5CDS-intronENST00000268261ENST00000340209PMM2chr16

8906963

+RBFOX1chr16

7568149

+
5CDS-intronENST00000268261ENST00000355637PMM2chr16

8906963

+RBFOX1chr16

7568149

+
5CDS-intronENST00000268261ENST00000436368PMM2chr16

8906963

+RBFOX1chr16

7568149

+
5CDS-intronENST00000268261ENST00000547338PMM2chr16

8906963

+RBFOX1chr16

7568149

+
5CDS-intronENST00000268261ENST00000547427PMM2chr16

8906963

+RBFOX1chr16

7568149

+
5CDS-intronENST00000268261ENST00000552089PMM2chr16

8906963

+RBFOX1chr16

7568149

+
5CDS-intronENST00000537352ENST00000311745PMM2chr16

8906963

+RBFOX1chr16

7568149

+
5CDS-intronENST00000537352ENST00000340209PMM2chr16

8906963

+RBFOX1chr16

7568149

+
5CDS-intronENST00000537352ENST00000355637PMM2chr16

8906963

+RBFOX1chr16

7568149

+
5CDS-intronENST00000537352ENST00000436368PMM2chr16

8906963

+RBFOX1chr16

7568149

+
5CDS-intronENST00000537352ENST00000547338PMM2chr16

8906963

+RBFOX1chr16

7568149

+
5CDS-intronENST00000537352ENST00000547427PMM2chr16

8906963

+RBFOX1chr16

7568149

+
5CDS-intronENST00000537352ENST00000552089PMM2chr16

8906963

+RBFOX1chr16

7568149

+
5CDS-intronENST00000539622ENST00000311745PMM2chr16

8906963

+RBFOX1chr16

7568149

+
5CDS-intronENST00000539622ENST00000340209PMM2chr16

8906963

+RBFOX1chr16

7568149

+
5CDS-intronENST00000539622ENST00000355637PMM2chr16

8906963

+RBFOX1chr16

7568149

+
5CDS-intronENST00000539622ENST00000436368PMM2chr16

8906963

+RBFOX1chr16

7568149

+
5CDS-intronENST00000539622ENST00000547338PMM2chr16

8906963

+RBFOX1chr16

7568149

+
5CDS-intronENST00000539622ENST00000547427PMM2chr16

8906963

+RBFOX1chr16

7568149

+
5CDS-intronENST00000539622ENST00000552089PMM2chr16

8906963

+RBFOX1chr16

7568149

+
5CDS-intronENST00000566983ENST00000311745PMM2chr16

8906963

+RBFOX1chr16

7568149

+
5CDS-intronENST00000566983ENST00000340209PMM2chr16

8906963

+RBFOX1chr16

7568149

+
5CDS-intronENST00000566983ENST00000355637PMM2chr16

8906963

+RBFOX1chr16

7568149

+
5CDS-intronENST00000566983ENST00000436368PMM2chr16

8906963

+RBFOX1chr16

7568149

+
5CDS-intronENST00000566983ENST00000547338PMM2chr16

8906963

+RBFOX1chr16

7568149

+
5CDS-intronENST00000566983ENST00000547427PMM2chr16

8906963

+RBFOX1chr16

7568149

+
5CDS-intronENST00000566983ENST00000552089PMM2chr16

8906963

+RBFOX1chr16

7568149

+
5CDS-intronENST00000569958ENST00000311745PMM2chr16

8906963

+RBFOX1chr16

7568149

+
5CDS-intronENST00000569958ENST00000340209PMM2chr16

8906963

+RBFOX1chr16

7568149

+
5CDS-intronENST00000569958ENST00000355637PMM2chr16

8906963

+RBFOX1chr16

7568149

+
5CDS-intronENST00000569958ENST00000436368PMM2chr16

8906963

+RBFOX1chr16

7568149

+
5CDS-intronENST00000569958ENST00000547338PMM2chr16

8906963

+RBFOX1chr16

7568149

+
5CDS-intronENST00000569958ENST00000547427PMM2chr16

8906963

+RBFOX1chr16

7568149

+
5CDS-intronENST00000569958ENST00000552089PMM2chr16

8906963

+RBFOX1chr16

7568149

+
In-frameENST00000268261ENST00000422070PMM2chr16

8906963

+RBFOX1chr16

7568149

+
In-frameENST00000268261ENST00000535565PMM2chr16

8906963

+RBFOX1chr16

7568149

+
In-frameENST00000268261ENST00000547372PMM2chr16

8906963

+RBFOX1chr16

7568149

+
In-frameENST00000268261ENST00000550418PMM2chr16

8906963

+RBFOX1chr16

7568149

+
In-frameENST00000268261ENST00000553186PMM2chr16

8906963

+RBFOX1chr16

7568149

+
In-frameENST00000537352ENST00000422070PMM2chr16

8906963

+RBFOX1chr16

7568149

+
In-frameENST00000537352ENST00000535565PMM2chr16

8906963

+RBFOX1chr16

7568149

+
In-frameENST00000537352ENST00000547372PMM2chr16

8906963

+RBFOX1chr16

7568149

+
In-frameENST00000537352ENST00000550418PMM2chr16

8906963

+RBFOX1chr16

7568149

+
In-frameENST00000537352ENST00000553186PMM2chr16

8906963

+RBFOX1chr16

7568149

+
In-frameENST00000539622ENST00000422070PMM2chr16

8906963

+RBFOX1chr16

7568149

+
In-frameENST00000539622ENST00000535565PMM2chr16

8906963

+RBFOX1chr16

7568149

+
In-frameENST00000539622ENST00000547372PMM2chr16

8906963

+RBFOX1chr16

7568149

+
In-frameENST00000539622ENST00000550418PMM2chr16

8906963

+RBFOX1chr16

7568149

+
In-frameENST00000539622ENST00000553186PMM2chr16

8906963

+RBFOX1chr16

7568149

+
In-frameENST00000566983ENST00000422070PMM2chr16

8906963

+RBFOX1chr16

7568149

+
In-frameENST00000566983ENST00000535565PMM2chr16

8906963

+RBFOX1chr16

7568149

+
In-frameENST00000566983ENST00000547372PMM2chr16

8906963

+RBFOX1chr16

7568149

+
In-frameENST00000566983ENST00000550418PMM2chr16

8906963

+RBFOX1chr16

7568149

+
In-frameENST00000566983ENST00000553186PMM2chr16

8906963

+RBFOX1chr16

7568149

+
In-frameENST00000569958ENST00000422070PMM2chr16

8906963

+RBFOX1chr16

7568149

+
In-frameENST00000569958ENST00000535565PMM2chr16

8906963

+RBFOX1chr16

7568149

+
In-frameENST00000569958ENST00000547372PMM2chr16

8906963

+RBFOX1chr16

7568149

+
In-frameENST00000569958ENST00000550418PMM2chr16

8906963

+RBFOX1chr16

7568149

+
In-frameENST00000569958ENST00000553186PMM2chr16

8906963

+RBFOX1chr16

7568149

+
intron-3CDSENST00000565837ENST00000422070PMM2chr16

8906963

+RBFOX1chr16

7568149

+
intron-3CDSENST00000565837ENST00000535565PMM2chr16

8906963

+RBFOX1chr16

7568149

+
intron-3CDSENST00000565837ENST00000547372PMM2chr16

8906963

+RBFOX1chr16

7568149

+
intron-3CDSENST00000565837ENST00000550418PMM2chr16

8906963

+RBFOX1chr16

7568149

+
intron-3CDSENST00000565837ENST00000553186PMM2chr16

8906963

+RBFOX1chr16

7568149

+
intron-intronENST00000565837ENST00000311745PMM2chr16

8906963

+RBFOX1chr16

7568149

+
intron-intronENST00000565837ENST00000340209PMM2chr16

8906963

+RBFOX1chr16

7568149

+
intron-intronENST00000565837ENST00000355637PMM2chr16

8906963

+RBFOX1chr16

7568149

+
intron-intronENST00000565837ENST00000436368PMM2chr16

8906963

+RBFOX1chr16

7568149

+
intron-intronENST00000565837ENST00000547338PMM2chr16

8906963

+RBFOX1chr16

7568149

+
intron-intronENST00000565837ENST00000547427PMM2chr16

8906963

+RBFOX1chr16

7568149

+
intron-intronENST00000565837ENST00000552089PMM2chr16

8906963

+RBFOX1chr16

7568149

+

check buttonORFfinder result based on the fusion transcript sequence of in-frame fusion genes.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandSeq length
(transcript)		BP loci
(transcript)		Predicted start
(transcript)		Predicted stop
(transcript)		Seq length
(amino acids)
ENST00000566983PMM2chr168906963+ENST00000550418RBFOX1chr167568149+20247622041928574
ENST00000566983PMM2chr168906963+ENST00000553186RBFOX1chr167568149+19437622041847547
ENST00000566983PMM2chr168906963+ENST00000547372RBFOX1chr167568149+38247622042006600
ENST00000566983PMM2chr168906963+ENST00000422070RBFOX1chr167568149+20947622041883559
ENST00000566983PMM2chr168906963+ENST00000535565RBFOX1chr167568149+19057622041769521
ENST00000268261PMM2chr168906963+ENST00000550418RBFOX1chr167568149+1967705661871601
ENST00000268261PMM2chr168906963+ENST00000553186RBFOX1chr167568149+1886705661790574
ENST00000268261PMM2chr168906963+ENST00000547372RBFOX1chr167568149+3767705661949627
ENST00000268261PMM2chr168906963+ENST00000422070RBFOX1chr167568149+2037705661826586
ENST00000268261PMM2chr168906963+ENST00000535565RBFOX1chr167568149+1848705661712548
ENST00000539622PMM2chr168906963+ENST00000550418RBFOX1chr167568149+18656031861769527
ENST00000539622PMM2chr168906963+ENST00000553186RBFOX1chr167568149+17846031861688500
ENST00000539622PMM2chr168906963+ENST00000547372RBFOX1chr167568149+36656031861847553
ENST00000539622PMM2chr168906963+ENST00000422070RBFOX1chr167568149+19356031861724512
ENST00000539622PMM2chr168906963+ENST00000535565RBFOX1chr167568149+17466031861610474
ENST00000537352PMM2chr168906963+ENST00000550418RBFOX1chr167568149+17484862221652476
ENST00000537352PMM2chr168906963+ENST00000553186RBFOX1chr167568149+16674862221571449
ENST00000537352PMM2chr168906963+ENST00000547372RBFOX1chr167568149+35484862221730502
ENST00000537352PMM2chr168906963+ENST00000422070RBFOX1chr167568149+18184862221607461
ENST00000537352PMM2chr168906963+ENST00000535565RBFOX1chr167568149+16294862221493423
ENST00000569958PMM2chr168906963+ENST00000550418RBFOX1chr167568149+1644382161548510
ENST00000569958PMM2chr168906963+ENST00000553186RBFOX1chr167568149+1563382161467483
ENST00000569958PMM2chr168906963+ENST00000547372RBFOX1chr167568149+3444382161626536
ENST00000569958PMM2chr168906963+ENST00000422070RBFOX1chr167568149+1714382161503495
ENST00000569958PMM2chr168906963+ENST00000535565RBFOX1chr167568149+1525382161389457

check buttonDeepORF prediction of the coding potential based on the fusion transcript sequence of in-frame fusion genes. DeepORF is a coding potential classifier based on convolutional neural network by comparing the real Ribo-seq data. If the no-coding score < 0.5 and coding score > 0.5, then the in-frame fusion transcript is predicted as being likely translated.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandNo-coding scoreCoding score
ENST00000566983ENST00000550418PMM2chr168906963+RBFOX1chr167568149+0.0011889390.9988111
ENST00000566983ENST00000553186PMM2chr168906963+RBFOX1chr167568149+0.0013460430.9986539
ENST00000566983ENST00000547372PMM2chr168906963+RBFOX1chr167568149+0.0004290080.999571
ENST00000566983ENST00000422070PMM2chr168906963+RBFOX1chr167568149+0.0006883420.9993117
ENST00000566983ENST00000535565PMM2chr168906963+RBFOX1chr167568149+0.0007093060.9992907
ENST00000268261ENST00000550418PMM2chr168906963+RBFOX1chr167568149+0.0007494090.9992506
ENST00000268261ENST00000553186PMM2chr168906963+RBFOX1chr167568149+0.0008543560.9991456
ENST00000268261ENST00000547372PMM2chr168906963+RBFOX1chr167568149+0.000244040.9997559
ENST00000268261ENST00000422070PMM2chr168906963+RBFOX1chr167568149+0.0004350540.99956495
ENST00000268261ENST00000535565PMM2chr168906963+RBFOX1chr167568149+0.0004745990.9995254
ENST00000539622ENST00000550418PMM2chr168906963+RBFOX1chr167568149+0.0014076960.9985923
ENST00000539622ENST00000553186PMM2chr168906963+RBFOX1chr167568149+0.001377540.9986224
ENST00000539622ENST00000547372PMM2chr168906963+RBFOX1chr167568149+0.0004049910.999595
ENST00000539622ENST00000422070PMM2chr168906963+RBFOX1chr167568149+0.0007941750.9992059
ENST00000539622ENST00000535565PMM2chr168906963+RBFOX1chr167568149+0.0008019570.999198
ENST00000537352ENST00000550418PMM2chr168906963+RBFOX1chr167568149+0.0013716120.9986284
ENST00000537352ENST00000553186PMM2chr168906963+RBFOX1chr167568149+0.0016411990.9983588
ENST00000537352ENST00000547372PMM2chr168906963+RBFOX1chr167568149+0.0003696590.99963033
ENST00000537352ENST00000422070PMM2chr168906963+RBFOX1chr167568149+0.0009467360.9990533
ENST00000537352ENST00000535565PMM2chr168906963+RBFOX1chr167568149+0.0017763140.9982237
ENST00000569958ENST00000550418PMM2chr168906963+RBFOX1chr167568149+0.0014366710.99856335
ENST00000569958ENST00000553186PMM2chr168906963+RBFOX1chr167568149+0.001516030.99848396
ENST00000569958ENST00000547372PMM2chr168906963+RBFOX1chr167568149+0.000444570.9995554
ENST00000569958ENST00000422070PMM2chr168906963+RBFOX1chr167568149+0.0008357360.9991642
ENST00000569958ENST00000535565PMM2chr168906963+RBFOX1chr167568149+0.0009296470.99907035

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Fusion Genomic Features for PMM2-RBFOX1


check buttonFusionAI prediction of the potential fusion gene breakpoint based on the pre-mature RNA sequence context (+/- 5kb of individual partner genes, total 20kb length sequence). FusionAI is a fusion gene breakpoint classifier based on convolutional neural network by comparing the fusion positive and negative sequence context of ~ 20K fusion gene data. From here, we can have the relative potentency of the 20K genomic sequence how individual sequnce will be likely used as the gene fusion breakpoints.
HgeneHchrHbpHstrandTgeneTchrTbpTstrand1-pp (fusion gene breakpoint)
PMM2chr168906963+RBFOX1chr167568148+7.03E-091
PMM2chr168906963+RBFOX1chr167568148+7.03E-091

check buttonDistribution of 44 human genomic features loci across 20kb length fusion breakpoint regions. We integrated a total of 44 different types of human genomic feature loci information across five big categories including virus integration sites, repeats, structural variants, chromatin states, and gene expression regulation. More details are in help page.
genomic feature

check buttonDistribution of 44 human genomic features loci across 20kb length fusion breakpoint regions that are ovelapped with the top 1% feature importance score regions. More details are in help page.
genomic feature of top 1%

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Fusion Protein Features for PMM2-RBFOX1


check button Four levels of functional features of fusion genes
Go to FGviewer search page for the most frequent breakpoint (https://ccsmweb.uth.edu/FGviewer/chr16:8906963/chr16:7568149)
- FGviewer provides the online visualization of the retention search of the protein functional features across DNA, RNA, protein, and pathological levels.
- How to search
1. Put your fusion gene symbol.
2. Press the tab key until there will be shown the breakpoint information filled.
4. Go down and press 'Search' tab twice.
4. Go down to have the hyperlink of the search result.
5. Click the hyperlink.
6. See the FGviewer result for your fusion gene.
FGviewer

check buttonMain function of each fusion partner protein. (from UniProt)
HgeneTgene
..
FUNCTION: Transcriptional activator which is required for calcium-dependent dendritic growth and branching in cortical neurons. Recruits CREB-binding protein (CREBBP) to nuclear bodies. Component of the CREST-BRG1 complex, a multiprotein complex that regulates promoter activation by orchestrating a calcium-dependent release of a repressor complex and a recruitment of an activator complex. In resting neurons, transcription of the c-FOS promoter is inhibited by BRG1-dependent recruitment of a phospho-RB1-HDAC1 repressor complex. Upon calcium influx, RB1 is dephosphorylated by calcineurin, which leads to release of the repressor complex. At the same time, there is increased recruitment of CREBBP to the promoter by a CREST-dependent mechanism, which leads to transcriptional activation. The CREST-BRG1 complex also binds to the NR2B promoter, and activity-dependent induction of NR2B expression involves a release of HDAC1 and recruitment of CREBBP (By similarity). {ECO:0000250}.FUNCTION: Transcriptional activator which is required for calcium-dependent dendritic growth and branching in cortical neurons. Recruits CREB-binding protein (CREBBP) to nuclear bodies. Component of the CREST-BRG1 complex, a multiprotein complex that regulates promoter activation by orchestrating a calcium-dependent release of a repressor complex and a recruitment of an activator complex. In resting neurons, transcription of the c-FOS promoter is inhibited by BRG1-dependent recruitment of a phospho-RB1-HDAC1 repressor complex. Upon calcium influx, RB1 is dephosphorylated by calcineurin, which leads to release of the repressor complex. At the same time, there is increased recruitment of CREBBP to the promoter by a CREST-dependent mechanism, which leads to transcriptional activation. The CREST-BRG1 complex also binds to the NR2B promoter, and activity-dependent induction of NR2B expression involves a release of HDAC1 and recruitment of CREBBP (By similarity). {ECO:0000250}.

check buttonRetention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at

download page


* Minus value of BPloci means that the break pointn is located before the CDS.
- In-frame and retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
TgeneRBFOX1chr16:8906963chr16:7568149ENST00000311745013117_19329419.0DomainRRM
TgeneRBFOX1chr16:8906963chr16:7568149ENST00000355637014117_19329396.0DomainRRM
TgeneRBFOX1chr16:8906963chr16:7568149ENST00000436368013117_19329393.0DomainRRM
TgeneRBFOX1chr16:8906963chr16:7568149ENST00000547338114117_1939398.0DomainRRM
TgeneRBFOX1chr16:8906963chr16:7568149ENST00000550418316117_1939398.0DomainRRM
TgeneRBFOX1chr16:8906963chr16:7568149ENST00000553186315117_1939371.0DomainRRM

- In-frame and not-retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note


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Fusion Gene Sequence for PMM2-RBFOX1


check button For in-frame fusion transcripts, we provide the fusion transcript sequences and fusion amino acid sequences. To have fusion amino acid sequence, we ran ORFfinder and chose the longest ORF among the all predicted ones.
>66648_66648_1_PMM2-RBFOX1_PMM2_chr16_8906963_ENST00000268261_RBFOX1_chr16_7568149_ENST00000422070_length(transcript)=2037nt_BP=705nt
CCGGAAGTTCCGGGCCGAGTTCCTCGTGCCAACGTGTCTTGTAAGGTGCGGCTAGAAACTGGGGACATGGCAGCGCCTGGCCCAGCGCTC
TGCCTCTTCGACGTGGATGGGACCCTCACCGCCCCGCGGCAGAAAATTACCAAAGAAATGGATGACTTCCTACAAAAATTGAGGCAGAAG
ATCAAAATCGGAGTGGTAGGCGGATCGGACTTTGAGAAAGTGCAGGAGCAACTGGGAAATGATGTGGTTGAAAAATACGATTATGTGTTT
CCAGAAAATGGCTTGGTAGCATACAAAGATGGGAAACTCTTGTGTAGACAGAATATTCAAAGTCATCTGGGTGAGGCCCTAATCCAAGAT
TTAATCAACTACTGTCTGAGCTACATTGCGAAAATTAAACTCCCGAAGAAGAGGGGTACTTTCATTGAATTCCGAAATGGGATGTTAAAC
GTGTCCCCTATTGGAAGAAGCTGCAGCCAAGAAGAACGCATTGAGTTCTACGAACTCGATAAAAAAGAAAATATAAGACAAAAGTTTGTA
GCAGATCTACGGAAAGAGTTTGCTGGAAAAGGCCTCACGTTTTCCATAGGAGGCCAGATCAGCTTTGATGTCTTTCCTGATGGATGGGAC
AAGAGATACTGTCTGCGACATGTGGAAAATGACGGTTATAAGACCATTTATTTCTTTGGAGACAAAACTATGCCAGGTAATCAGGAAGCA
GCCGCTGCCCCTGACACAATGGCTCAGCCTTACGCTTCGGCCCAGTTTGCTCCCCCGCAGAACGGTATCCCCGCGGAATACACGGCCCCT
CATCCCCACCCCGCGCCAGAGTACACAGGCCAGACCACGGTTCCCGAGCACACATTAAACCTGTACCCTCCCGCCCAGACGCACTCCGAG
CAGAGCCCGGCGGACACGAGCGCTCAGACCGTCTCTGGCACCGCCACACAGACAGATGACGCAGCACCGACGGATGGCCAGCCCCAGACA
CAACCTTCTGAAAACACGGAAAACAAGTCTCAGCCCAAGCGGCTGCATGTCTCCAATATCCCCTTCAGGTTCCGGGATCCGGACCTCAGA
CAAATGTTTGGTCAATTTGGTAAAATCTTAGATGTTGAAATTATTTTTAATGAGCGAGGCTCAAAGGGATTTGGTTTCGTAACTTTCGAA
AATAGTGCCGATGCGGACAGGGCGAGGGAGAAATTACACGGCACCGTGGTAGAGGGCCGTAAAATCGAGGTAAATAATGCCACAGCACGT
GTAATGACAAATAAAAAGACCGTCAACCCTTATACAAATGGCTGGAAATTGAATCCAGTTGTGGGTGCAGTCTACAGTCCCGAATTCTAT
GCAGGCACGGTCCTGTTGTGCCAGGCCAACCAGGAGGGATCTTCCATGTACAGTGCCCCCAGTTCACTTGTATATACTTCTGCAATGCCA
GGCTTCCCGTATCCAGCAGCCACCGCCGCGGCCGCCTACCGAGGGGCGCACCTGCGAGGCCGCGGTCGCACCGTGTACAACACCTTCAGG
GCCGCGGCGCCCCCGCCCCCGATCCCGGCCTACGGCGGTGTTGTTTACCAGGATGGATTTTATGGTGCAGACATTTATGGTGGTTATGCT
GCATACCGCTACGCCCAGCCTACCCCTGCCACTGCCGCTGCCTACAGTGACAGTTACGGACGAGTTTATGCTGCCGACCCCTACCACCAC
GCACTTGCTCCAGCCCCCACCTACGGCGTTGGTGCCATGCCCCAAGGTTCCAGCCCCAGCACAGACTTCAGAGGAGCTAAGCTGCACACT
TCCAGGCCTCTGCTGTCAGGCAGCTGAGAATCTGACTGCCTCTCCTCCCCTATTACAATTCATGTTTAAAGTCATAGTCGCCCAGGAAAG
AAAATAGAGAGGGGCACACTTTGTGTGTGTACCTAGTACATAAGAAAGTAGAAGGAATCAGCTGGGTTTGGGGGTTGCCTTTTGTTTTGG

>66648_66648_1_PMM2-RBFOX1_PMM2_chr16_8906963_ENST00000268261_RBFOX1_chr16_7568149_ENST00000422070_length(amino acids)=586AA_BP=213
MAAPGPALCLFDVDGTLTAPRQKITKEMDDFLQKLRQKIKIGVVGGSDFEKVQEQLGNDVVEKYDYVFPENGLVAYKDGKLLCRQNIQSH
LGEALIQDLINYCLSYIAKIKLPKKRGTFIEFRNGMLNVSPIGRSCSQEERIEFYELDKKENIRQKFVADLRKEFAGKGLTFSIGGQISF
DVFPDGWDKRYCLRHVENDGYKTIYFFGDKTMPGNQEAAAAPDTMAQPYASAQFAPPQNGIPAEYTAPHPHPAPEYTGQTTVPEHTLNLY
PPAQTHSEQSPADTSAQTVSGTATQTDDAAPTDGQPQTQPSENTENKSQPKRLHVSNIPFRFRDPDLRQMFGQFGKILDVEIIFNERGSK
GFGFVTFENSADADRAREKLHGTVVEGRKIEVNNATARVMTNKKTVNPYTNGWKLNPVVGAVYSPEFYAGTVLLCQANQEGSSMYSAPSS
LVYTSAMPGFPYPAATAAAAYRGAHLRGRGRTVYNTFRAAAPPPPIPAYGGVVYQDGFYGADIYGGYAAYRYAQPTPATAAAYSDSYGRV

--------------------------------------------------------------
>66648_66648_2_PMM2-RBFOX1_PMM2_chr16_8906963_ENST00000268261_RBFOX1_chr16_7568149_ENST00000535565_length(transcript)=1848nt_BP=705nt
CCGGAAGTTCCGGGCCGAGTTCCTCGTGCCAACGTGTCTTGTAAGGTGCGGCTAGAAACTGGGGACATGGCAGCGCCTGGCCCAGCGCTC
TGCCTCTTCGACGTGGATGGGACCCTCACCGCCCCGCGGCAGAAAATTACCAAAGAAATGGATGACTTCCTACAAAAATTGAGGCAGAAG
ATCAAAATCGGAGTGGTAGGCGGATCGGACTTTGAGAAAGTGCAGGAGCAACTGGGAAATGATGTGGTTGAAAAATACGATTATGTGTTT
CCAGAAAATGGCTTGGTAGCATACAAAGATGGGAAACTCTTGTGTAGACAGAATATTCAAAGTCATCTGGGTGAGGCCCTAATCCAAGAT
TTAATCAACTACTGTCTGAGCTACATTGCGAAAATTAAACTCCCGAAGAAGAGGGGTACTTTCATTGAATTCCGAAATGGGATGTTAAAC
GTGTCCCCTATTGGAAGAAGCTGCAGCCAAGAAGAACGCATTGAGTTCTACGAACTCGATAAAAAAGAAAATATAAGACAAAAGTTTGTA
GCAGATCTACGGAAAGAGTTTGCTGGAAAAGGCCTCACGTTTTCCATAGGAGGCCAGATCAGCTTTGATGTCTTTCCTGATGGATGGGAC
AAGAGATACTGTCTGCGACATGTGGAAAATGACGGTTATAAGACCATTTATTTCTTTGGAGACAAAACTATGCCAGGTAATCAGGAAGCA
GCCGCTGCCCCTGACACAATGGCTCAGCCTTACGCTTCGGCCCAGTTTGCTCCCCCGCAGAACGGTATCCCCGCGGAATACACGGCCCCT
CATCCCCACCCCGCGCCAGAGTACACAGGCCAGACCACGGTTCCCGAGCACACATTAAACCTGTACCCTCCCGCCCAGACGCACTCCGAG
CAGAGCCCGGCGGACACGAGCGCTCAGACCGTCTCTGGCACCGCCACACAATTTGGTAAAATCTTAGATGTTGAAATTATTTTTAATGAG
CGAGGCTCAAAGGTAAATAATGCCACAGCACGTGTAATGACAAATAAAAAGACCGTCAACCCTTATACAAATGGCTGGAAATTGAATCCA
GTTGTGGGTGCAGTCTACAGTCCCGAATTCTATGCAGGCACGGTCCTGTTGTGCCAGGCCAACCAGGAGGGATCTTCCATGTACAGTGCC
CCCAGTTCACTTGTATATACTTCTGCAATGCCAGGCTTCCCGTATCCAGCAGCCACCGCCGCGGCCGCCTACCGAGGGGCGCACCTGCGA
GGCCGCGGTCGCACCGTGTACAACACCTTCAGGGCCGCGGCGCCCCCGCCCCCGATCCCGGCCTACGGCGGTGTTGTTTACCAGGATGGA
TTTTATGGTGCAGACATTTATGGTGGTTATGCTGCATACCGCTACGCCCAGCCTACCCCTGCCACTGCCGCTGCCTACAGTGACAGAAAT
CAGTTCGTCTTCGTTGCAGCAGATGAAATTTCTTGTAACACCTCTGCAGTTACGGACGAGTTTATGCTGCCGACCCCTACCACCACGCAC
TTGCTCCAGCCCCCACCTACGGCGTTGGTGCCATGCCCCAAGGTTCCAGCCCCAGCACAGACTTCAGAGGAGCTAAGCTGCACACTTCCA
GGCCTCTGCTGTCAGGCAGCTGAGAATCTGACTGCCTCTCCTCCCCTATTACAATTCATGTTTAAAGTCATAGTCGCCCAGGAAAGAAAA
TAGAGAGGGGCACACTTTGTGTGTGTACCTAGTACATAAGAAAGTAGAAGGAATCAGCTGGGTTTGGGGGTTGCCTTTTGTTTTGGGGCA

>66648_66648_2_PMM2-RBFOX1_PMM2_chr16_8906963_ENST00000268261_RBFOX1_chr16_7568149_ENST00000535565_length(amino acids)=548AA_BP=213
MAAPGPALCLFDVDGTLTAPRQKITKEMDDFLQKLRQKIKIGVVGGSDFEKVQEQLGNDVVEKYDYVFPENGLVAYKDGKLLCRQNIQSH
LGEALIQDLINYCLSYIAKIKLPKKRGTFIEFRNGMLNVSPIGRSCSQEERIEFYELDKKENIRQKFVADLRKEFAGKGLTFSIGGQISF
DVFPDGWDKRYCLRHVENDGYKTIYFFGDKTMPGNQEAAAAPDTMAQPYASAQFAPPQNGIPAEYTAPHPHPAPEYTGQTTVPEHTLNLY
PPAQTHSEQSPADTSAQTVSGTATQFGKILDVEIIFNERGSKVNNATARVMTNKKTVNPYTNGWKLNPVVGAVYSPEFYAGTVLLCQANQ
EGSSMYSAPSSLVYTSAMPGFPYPAATAAAAYRGAHLRGRGRTVYNTFRAAAPPPPIPAYGGVVYQDGFYGADIYGGYAAYRYAQPTPAT
AAAYSDRNQFVFVAADEISCNTSAVTDEFMLPTPTTTHLLQPPPTALVPCPKVPAPAQTSEELSCTLPGLCCQAAENLTASPPLLQFMFK

--------------------------------------------------------------
>66648_66648_3_PMM2-RBFOX1_PMM2_chr16_8906963_ENST00000268261_RBFOX1_chr16_7568149_ENST00000547372_length(transcript)=3767nt_BP=705nt
CCGGAAGTTCCGGGCCGAGTTCCTCGTGCCAACGTGTCTTGTAAGGTGCGGCTAGAAACTGGGGACATGGCAGCGCCTGGCCCAGCGCTC
TGCCTCTTCGACGTGGATGGGACCCTCACCGCCCCGCGGCAGAAAATTACCAAAGAAATGGATGACTTCCTACAAAAATTGAGGCAGAAG
ATCAAAATCGGAGTGGTAGGCGGATCGGACTTTGAGAAAGTGCAGGAGCAACTGGGAAATGATGTGGTTGAAAAATACGATTATGTGTTT
CCAGAAAATGGCTTGGTAGCATACAAAGATGGGAAACTCTTGTGTAGACAGAATATTCAAAGTCATCTGGGTGAGGCCCTAATCCAAGAT
TTAATCAACTACTGTCTGAGCTACATTGCGAAAATTAAACTCCCGAAGAAGAGGGGTACTTTCATTGAATTCCGAAATGGGATGTTAAAC
GTGTCCCCTATTGGAAGAAGCTGCAGCCAAGAAGAACGCATTGAGTTCTACGAACTCGATAAAAAAGAAAATATAAGACAAAAGTTTGTA
GCAGATCTACGGAAAGAGTTTGCTGGAAAAGGCCTCACGTTTTCCATAGGAGGCCAGATCAGCTTTGATGTCTTTCCTGATGGATGGGAC
AAGAGATACTGTCTGCGACATGTGGAAAATGACGGTTATAAGACCATTTATTTCTTTGGAGACAAAACTATGCCAGGTAATCAGGAAGCA
GCCGCTGCCCCTGACACAATGGCTCAGCCTTACGCTTCGGCCCAGTTTGCTCCCCCGCAGAACGGTATCCCCGCGGAATACACGGCCCCT
CATCCCCACCCCGCGCCAGAGTACACAGGCCAGACCACGGTTCCCGAGCACACATTAAACCTGTACCCTCCCGCCCAGACGCACTCCGAG
CAGAGCCCGGCGGACACGAGCGCTCAGACCGTCTCTGGCACCGCCACACAGACAGATGACGCAGCACCGACGGATGGCCAGCCCCAGACA
CAACCTTCTGAAAACACGGAAAACAAGTCTCAGCCCAAGCGGCTGCATGTCTCCAATATCCCCTTCAGGTTCCGGGATCCGGACCTCAGA
CAAATGTTTGGTCAATTTGGTAAAATCTTAGATGTTGAAATTATTTTTAATGAGCGAGGCTCAAAGGGATTTGGTTTCGTAACTTTCGAA
AATAGTGCCGATGCGGACAGGGCGAGGGAGAAATTACACGGCACCGTGGTAGAGGGCCGTAAAATCGAGGTAAATAATGCCACAGCACGT
GTAATGACAAATAAAAAGACCGTCAACCCTTATACAAATGGCTGGAAATTGAATCCAGTTGTGGGTGCAGTCTACAGTCCCGAATTCTAT
GCAGGCACGGTCCTGTTGTGCCAGGCCAACCAGGAGGGATCTTCCATGTACAGTGCCCCCAGTTCACTTGTATATACTTCTGCAATGCCA
GGCTTCCCGTATCCAGCAGCCACCGCCGCGGCCGCCTACCGAGGGGCGCACCTGCGAGGCCGCGGTCGCACCGTGTACAACACCTTCAGG
GCCGCGGCGCCCCCGCCCCCGATCCCGGCCTACGGCGGTGTTGTTTACCAGGATGGATTTTATGGTGCAGACATTTATGGTGGTTATGCT
GCATACCGCTACGCCCAGCCTACCCCTGCCACTGCCGCTGCCTACAGTGACAGAAATCAGTTCGTCTTCGTTGCAGCAGATGAAATTTCT
TGTAACACCTCTGCAGTTACGGACGAGTTTATGCTGCCGACCCCTACCACCACGCACTTGCTCCAGCCCCCACCTACGGCGTTGGTGCCA
TGCCCCAAGGTTCCAGCCCCAGCACAGACTTCAGAGGAGCTAAGCTGCACACTTCCAGGCCTCTGCTGTCAGGCAGCTGAGAATCTGACT
GCCTCTCCTCCCCTATTACAATTCATGTTTAAAGTCATAGTCGCCCAGGAAAGAAAATAGAGAGGGGCACACTTTGTGTGTGTACCTAGT
ACATAAGAAAGTAGAAGGAATCAGCTGGGTTTGGGGGTTGCCTTTTGTTTTGGGGCAGGTCTGGGTTTTTGTTTTGGGAGGGGGTGGGGG
GAGGGTAAAAAATGGGAGGTAAGGGTGGGGTGAACTTGCCTGTACTTGTTCAAACTTCTATGCACTGAAACTCTTGAGTACAGTAAGACG
TGCCCATCACGTGAGAGCATATGCAATCATTACAAAGCTTTGGCATGCAGTTTTCTGCTTGGATCAAGAATATCAGTCCTTACCCTAAAA
ATGAATCCCCATAGGCATTCATTTGAATTGCCAATACTTTTAGAAAAAGGAAATCGTTAAGTGCCACCTTGTAGCCATTAAAACCATGGC
CGGACAGTTCACTGAAGCTCAGTCATAGAAATTCAGCCATGATTTGGAAGCATTGTTTTGCACAAGCTTAATTACATCAAGCAATTCATC
TGTACAACTCCACAACTCCCTTCTCAAGATCAGATTCCATACAGCTTACAGAGCCAAGTTAAGTAAGAAGTAGGTTGAGATTTTCATCCC
AATTCTGCATTCAACAACTCTGCTTCAACACCTAGTCCACATGAGGAATGTGTTGGAGAGTTGAATTACATTCAACAACTGGTCCAAATT
CAACCTCAAGTGCAGATTATTCTGTTATAAAAAAATGAGACAGTGAAAATCCTTCCATTGTCCAGCTTATAATAGAGTCCTTTTAGCTAA
GAGGACTGGCTGACAGAATTTGGTTTTGCAGGGAATTTCTTTAGGAGGAGCTATTGGGGAAGGTCAGGAATGGCCCTATCTTTAGTTCTC
CAAGAATGACCTGGGATGGGTAGGGGGTGCCTCCATTTCGGTTGGTTTTGAGTGTCTATTTTTCACATTAGTCTTTTTGATGATCCACAT
GTTGCAAAAGGAAAATGTAAAAAACACACCCCTCAAATTGCTTTGTTTCAGAATGCTTTTGCACCTTTGACTGATGCCAAGACTAGGAGC
CATGCTGATGATGTGGGTCTCGTTCTTTCTTCATTGCAGGCTAGTATATACCGAGGGGGATACAACCGTTTTGCTCCATACTAAATGACA
AAACCATAAAAACCTTCCAATGTGGGGAGAAAGGAAGCTTTCCGAGGCCTGAGTATTGCAATACATGCAGTAGTACATCATTTTAGCAAC
TCTAAAAAAAAAAAAAATACAAATAAAAAGGAAAAAAAATTACATTTTTTATCTTATACCTCAGATATTTTGTTCTGTGTATTTTAATAT
TGTGGGTCTTTAATTTCTGAAGGTTCCGTAGTTTGGTTGCTGGCTGTAGGAGTTTTTGTGGTTGATCTAGACAGATGCTAGATAATGAAT
AAAAACTGGTTTAGGGCCATATCCAGAGTGCTATATTATGTAAATGAATTATATATGCTGAATATTAAGCTACTGGGGTTATCAGCTATT
TGGGAAGAGTGTAAGTGACTACAGTAGTCATTTTTTTCTGCACCTGCATTATTTTATTTTGCGAAAGGGGAGGTTGGGAGGGGCTTAGGG
GATTGGAACTGGGGTTTGGCTGAAAGAAAAAAAAAAAAATGTAACTGATGAATCTAAACGACCCACTGCACCAACAATCATTTATCAATG
GTTCTAAGTTACTCATTGCCAGTTCAAGCCAAAGGTCATGTTGTTAAGGGGGTGCTTCTAGTAGCACTTGTGCATCTGAGTTGAATGAAG

>66648_66648_3_PMM2-RBFOX1_PMM2_chr16_8906963_ENST00000268261_RBFOX1_chr16_7568149_ENST00000547372_length(amino acids)=627AA_BP=213
MAAPGPALCLFDVDGTLTAPRQKITKEMDDFLQKLRQKIKIGVVGGSDFEKVQEQLGNDVVEKYDYVFPENGLVAYKDGKLLCRQNIQSH
LGEALIQDLINYCLSYIAKIKLPKKRGTFIEFRNGMLNVSPIGRSCSQEERIEFYELDKKENIRQKFVADLRKEFAGKGLTFSIGGQISF
DVFPDGWDKRYCLRHVENDGYKTIYFFGDKTMPGNQEAAAAPDTMAQPYASAQFAPPQNGIPAEYTAPHPHPAPEYTGQTTVPEHTLNLY
PPAQTHSEQSPADTSAQTVSGTATQTDDAAPTDGQPQTQPSENTENKSQPKRLHVSNIPFRFRDPDLRQMFGQFGKILDVEIIFNERGSK
GFGFVTFENSADADRAREKLHGTVVEGRKIEVNNATARVMTNKKTVNPYTNGWKLNPVVGAVYSPEFYAGTVLLCQANQEGSSMYSAPSS
LVYTSAMPGFPYPAATAAAAYRGAHLRGRGRTVYNTFRAAAPPPPIPAYGGVVYQDGFYGADIYGGYAAYRYAQPTPATAAAYSDRNQFV

--------------------------------------------------------------
>66648_66648_4_PMM2-RBFOX1_PMM2_chr16_8906963_ENST00000268261_RBFOX1_chr16_7568149_ENST00000550418_length(transcript)=1967nt_BP=705nt
CCGGAAGTTCCGGGCCGAGTTCCTCGTGCCAACGTGTCTTGTAAGGTGCGGCTAGAAACTGGGGACATGGCAGCGCCTGGCCCAGCGCTC
TGCCTCTTCGACGTGGATGGGACCCTCACCGCCCCGCGGCAGAAAATTACCAAAGAAATGGATGACTTCCTACAAAAATTGAGGCAGAAG
ATCAAAATCGGAGTGGTAGGCGGATCGGACTTTGAGAAAGTGCAGGAGCAACTGGGAAATGATGTGGTTGAAAAATACGATTATGTGTTT
CCAGAAAATGGCTTGGTAGCATACAAAGATGGGAAACTCTTGTGTAGACAGAATATTCAAAGTCATCTGGGTGAGGCCCTAATCCAAGAT
TTAATCAACTACTGTCTGAGCTACATTGCGAAAATTAAACTCCCGAAGAAGAGGGGTACTTTCATTGAATTCCGAAATGGGATGTTAAAC
GTGTCCCCTATTGGAAGAAGCTGCAGCCAAGAAGAACGCATTGAGTTCTACGAACTCGATAAAAAAGAAAATATAAGACAAAAGTTTGTA
GCAGATCTACGGAAAGAGTTTGCTGGAAAAGGCCTCACGTTTTCCATAGGAGGCCAGATCAGCTTTGATGTCTTTCCTGATGGATGGGAC
AAGAGATACTGTCTGCGACATGTGGAAAATGACGGTTATAAGACCATTTATTTCTTTGGAGACAAAACTATGCCAGGTAATCAGGAAGCA
GCCGCTGCCCCTGACACAATGGCTCAGCCTTACGCTTCGGCCCAGTTTGCTCCCCCGCAGAACGGTATCCCCGCGGAATACACGGCCCCT
CATCCCCACCCCGCGCCAGAGTACACAGGCCAGACCACGGTTCCCGAGCACACATTAAACCTGTACCCTCCCGCCCAGACGCACTCCGAG
CAGAGCCCGGCGGACACGAGCGCTCAGACCGTCTCTGGCACCGCCACACAGACAGATGACGCAGCACCGACGGATGGCCAGCCCCAGACA
CAACCTTCTGAAAACACGGAAAACAAGTCTCAGCCCAAGCGGCTGCATGTCTCCAATATCCCCTTCAGGTTCCGGGATCCGGACCTCAGA
CAAATGTTTGGTCAATTTGGTAAAATCTTAGATGTTGAAATTATTTTTAATGAGCGAGGCTCAAAGGGATTTGGTTTCGTAACTTTCGAA
AATAGTGCCGATGCGGACAGGGCGAGGGAGAAATTACACGGCACCGTGGTAGAGGGCCGTAAAATCGAGGTAAATAATGCCACAGCACGT
GTAATGACAAATAAAAAGACCGTCAACCCTTATACAAATGGCTGGAAATTGAATCCAGTTGTGGGTGCAGTCTACAGTCCCGAATTCTAT
GCAGGCACGGTCCTGTTGTGCCAGGCCAACCAGGAGGGATCTTCCATGTACAGTGCCCCCAGTTCACTTGTATATACTTCTGCAATGCCA
GGCTTCCCGTATCCAGCAGCCACCGCCGCGGCCGCCTACCGAGGGGCGCACCTGCGAGGCCGCGGTCGCACCGTGTACAACACCTTCAGG
GCCGCGGCGCCCCCGCCCCCGATCCCGGCCTACGGCGGTGTTGTTTACCAGGATGGATTTTATGGTGCAGACATTTATGGTGGTTATGCT
GCATACCGCTACGCCCAGCCTACCCCTGCCACTGCCGCTGCCTACAGTGACAGTTACGGACGAGTTTATGCTGCCGACCCCTACCACCAC
GCACTTGCTCCAGCCCCCACCTACGGCGTTGGTGCCATGAATGCTTTTGCACCTTTGACTGATGCCAAGACTAGGAGCCATGCTGATGAT
GTGGGTCTCGTTCTTTCTTCATTGCAGGCTAGTATATACCGAGGGGGATACAACCGTTTTGCTCCATACTAAATGACAAAACCATAAAAA

>66648_66648_4_PMM2-RBFOX1_PMM2_chr16_8906963_ENST00000268261_RBFOX1_chr16_7568149_ENST00000550418_length(amino acids)=601AA_BP=213
MAAPGPALCLFDVDGTLTAPRQKITKEMDDFLQKLRQKIKIGVVGGSDFEKVQEQLGNDVVEKYDYVFPENGLVAYKDGKLLCRQNIQSH
LGEALIQDLINYCLSYIAKIKLPKKRGTFIEFRNGMLNVSPIGRSCSQEERIEFYELDKKENIRQKFVADLRKEFAGKGLTFSIGGQISF
DVFPDGWDKRYCLRHVENDGYKTIYFFGDKTMPGNQEAAAAPDTMAQPYASAQFAPPQNGIPAEYTAPHPHPAPEYTGQTTVPEHTLNLY
PPAQTHSEQSPADTSAQTVSGTATQTDDAAPTDGQPQTQPSENTENKSQPKRLHVSNIPFRFRDPDLRQMFGQFGKILDVEIIFNERGSK
GFGFVTFENSADADRAREKLHGTVVEGRKIEVNNATARVMTNKKTVNPYTNGWKLNPVVGAVYSPEFYAGTVLLCQANQEGSSMYSAPSS
LVYTSAMPGFPYPAATAAAAYRGAHLRGRGRTVYNTFRAAAPPPPIPAYGGVVYQDGFYGADIYGGYAAYRYAQPTPATAAAYSDSYGRV

--------------------------------------------------------------
>66648_66648_5_PMM2-RBFOX1_PMM2_chr16_8906963_ENST00000268261_RBFOX1_chr16_7568149_ENST00000553186_length(transcript)=1886nt_BP=705nt
CCGGAAGTTCCGGGCCGAGTTCCTCGTGCCAACGTGTCTTGTAAGGTGCGGCTAGAAACTGGGGACATGGCAGCGCCTGGCCCAGCGCTC
TGCCTCTTCGACGTGGATGGGACCCTCACCGCCCCGCGGCAGAAAATTACCAAAGAAATGGATGACTTCCTACAAAAATTGAGGCAGAAG
ATCAAAATCGGAGTGGTAGGCGGATCGGACTTTGAGAAAGTGCAGGAGCAACTGGGAAATGATGTGGTTGAAAAATACGATTATGTGTTT
CCAGAAAATGGCTTGGTAGCATACAAAGATGGGAAACTCTTGTGTAGACAGAATATTCAAAGTCATCTGGGTGAGGCCCTAATCCAAGAT
TTAATCAACTACTGTCTGAGCTACATTGCGAAAATTAAACTCCCGAAGAAGAGGGGTACTTTCATTGAATTCCGAAATGGGATGTTAAAC
GTGTCCCCTATTGGAAGAAGCTGCAGCCAAGAAGAACGCATTGAGTTCTACGAACTCGATAAAAAAGAAAATATAAGACAAAAGTTTGTA
GCAGATCTACGGAAAGAGTTTGCTGGAAAAGGCCTCACGTTTTCCATAGGAGGCCAGATCAGCTTTGATGTCTTTCCTGATGGATGGGAC
AAGAGATACTGTCTGCGACATGTGGAAAATGACGGTTATAAGACCATTTATTTCTTTGGAGACAAAACTATGCCAGGTAATCAGGAAGCA
GCCGCTGCCCCTGACACAATGGCTCAGCCTTACGCTTCGGCCCAGTTTGCTCCCCCGCAGAACGGTATCCCCGCGGAATACACGGCCCCT
CATCCCCACCCCGCGCCAGAGTACACAGGCCAGACCACGGTTCCCGAGCACACATTAAACCTGTACCCTCCCGCCCAGACGCACTCCGAG
CAGAGCCCGGCGGACACGAGCGCTCAGACCGTCTCTGGCACCGCCACACAGACAGATGACGCAGCACCGACGGATGGCCAGCCCCAGACA
CAACCTTCTGAAAACACGGAAAACAAGTCTCAGCCCAAGCGGCTGCATGTCTCCAATATCCCCTTCAGGTTCCGGGATCCGGACCTCAGA
CAAATGTTTGGTCAATTTGGTAAAATCTTAGATGTTGAAATTATTTTTAATGAGCGAGGCTCAAAGGGATTTGGTTTCGTAACTTTCGAA
AATAGTGCCGATGCGGACAGGGCGAGGGAGAAATTACACGGCACCGTGGTAGAGGGCCGTAAAATCGAGGTAAATAATGCCACAGCACGT
GTAATGACAAATAAAAAGACCGTCAACCCTTATACAAATGGCTGGAAATTGAATCCAGTTGTGGGTGCAGTCTACAGTCCCGAATTCTAT
GCAGTGCCAGGCTTCCCGTATCCAGCAGCCACCGCCGCGGCCGCCTACCGAGGGGCGCACCTGCGAGGCCGCGGTCGCACCGTGTACAAC
ACCTTCAGGGCCGCGGCGCCCCCGCCCCCGATCCCGGCCTACGGCGGTGTTGTTTACCAGGATGGATTTTATGGTGCAGACATTTATGGT
GGTTATGCTGCATACCGCTACGCCCAGCCTACCCCTGCCACTGCCGCTGCCTACAGTGACAGTTACGGACGAGTTTATGCTGCCGACCCC
TACCACCACGCACTTGCTCCAGCCCCCACCTACGGCGTTGGTGCCATGAATGCTTTTGCACCTTTGACTGATGCCAAGACTAGGAGCCAT
GCTGATGATGTGGGTCTCGTTCTTTCTTCATTGCAGGCTAGTATATACCGAGGGGGATACAACCGTTTTGCTCCATACTAAATGACAAAA

>66648_66648_5_PMM2-RBFOX1_PMM2_chr16_8906963_ENST00000268261_RBFOX1_chr16_7568149_ENST00000553186_length(amino acids)=574AA_BP=213
MAAPGPALCLFDVDGTLTAPRQKITKEMDDFLQKLRQKIKIGVVGGSDFEKVQEQLGNDVVEKYDYVFPENGLVAYKDGKLLCRQNIQSH
LGEALIQDLINYCLSYIAKIKLPKKRGTFIEFRNGMLNVSPIGRSCSQEERIEFYELDKKENIRQKFVADLRKEFAGKGLTFSIGGQISF
DVFPDGWDKRYCLRHVENDGYKTIYFFGDKTMPGNQEAAAAPDTMAQPYASAQFAPPQNGIPAEYTAPHPHPAPEYTGQTTVPEHTLNLY
PPAQTHSEQSPADTSAQTVSGTATQTDDAAPTDGQPQTQPSENTENKSQPKRLHVSNIPFRFRDPDLRQMFGQFGKILDVEIIFNERGSK
GFGFVTFENSADADRAREKLHGTVVEGRKIEVNNATARVMTNKKTVNPYTNGWKLNPVVGAVYSPEFYAVPGFPYPAATAAAAYRGAHLR
GRGRTVYNTFRAAAPPPPIPAYGGVVYQDGFYGADIYGGYAAYRYAQPTPATAAAYSDSYGRVYAADPYHHALAPAPTYGVGAMNAFAPL

--------------------------------------------------------------
>66648_66648_6_PMM2-RBFOX1_PMM2_chr16_8906963_ENST00000537352_RBFOX1_chr16_7568149_ENST00000422070_length(transcript)=1818nt_BP=486nt
GCTAGAAACTGGGGACATGGCAGCGCCTGGCCCAGCGCTCTGCCTCTTCGACGTGGATGGGACCCTCACCGCCCCGCGGCAGAAAATTAC
CAAAGAAATGGATGACTTCCTACAAAAATTGAGGCAGAAGATCAAAATCGGAGTGGTAGGCGGATCGGACTTTGAGAAAGTGCAGGAGCA
ACTGGGAAATGATGGGGTACTTTCATTGAATTCCGAAATGGGATGTTAAACGTGTCCCCTATTGGAAGAAGCTGCAGCCAAGAAGAACGC
ATTGAGTTCTACGAACTCGATAAAAAAGAAAATATAAGACAAAAGTTTGTAGCAGATCTACGGAAAGAGTTTGCTGGAAAAGGCCTCACG
TTTTCCATAGGAGGCCAGATCAGCTTTGATGTCTTTCCTGATGGATGGGACAAGAGATACTGTCTGCGACATGTGGAAAATGACGGTTAT
AAGACCATTTATTTCTTTGGAGACAAAACTATGCCAGGTAATCAGGAAGCAGCCGCTGCCCCTGACACAATGGCTCAGCCTTACGCTTCG
GCCCAGTTTGCTCCCCCGCAGAACGGTATCCCCGCGGAATACACGGCCCCTCATCCCCACCCCGCGCCAGAGTACACAGGCCAGACCACG
GTTCCCGAGCACACATTAAACCTGTACCCTCCCGCCCAGACGCACTCCGAGCAGAGCCCGGCGGACACGAGCGCTCAGACCGTCTCTGGC
ACCGCCACACAGACAGATGACGCAGCACCGACGGATGGCCAGCCCCAGACACAACCTTCTGAAAACACGGAAAACAAGTCTCAGCCCAAG
CGGCTGCATGTCTCCAATATCCCCTTCAGGTTCCGGGATCCGGACCTCAGACAAATGTTTGGTCAATTTGGTAAAATCTTAGATGTTGAA
ATTATTTTTAATGAGCGAGGCTCAAAGGGATTTGGTTTCGTAACTTTCGAAAATAGTGCCGATGCGGACAGGGCGAGGGAGAAATTACAC
GGCACCGTGGTAGAGGGCCGTAAAATCGAGGTAAATAATGCCACAGCACGTGTAATGACAAATAAAAAGACCGTCAACCCTTATACAAAT
GGCTGGAAATTGAATCCAGTTGTGGGTGCAGTCTACAGTCCCGAATTCTATGCAGGCACGGTCCTGTTGTGCCAGGCCAACCAGGAGGGA
TCTTCCATGTACAGTGCCCCCAGTTCACTTGTATATACTTCTGCAATGCCAGGCTTCCCGTATCCAGCAGCCACCGCCGCGGCCGCCTAC
CGAGGGGCGCACCTGCGAGGCCGCGGTCGCACCGTGTACAACACCTTCAGGGCCGCGGCGCCCCCGCCCCCGATCCCGGCCTACGGCGGT
GTTGTTTACCAGGATGGATTTTATGGTGCAGACATTTATGGTGGTTATGCTGCATACCGCTACGCCCAGCCTACCCCTGCCACTGCCGCT
GCCTACAGTGACAGTTACGGACGAGTTTATGCTGCCGACCCCTACCACCACGCACTTGCTCCAGCCCCCACCTACGGCGTTGGTGCCATG
CCCCAAGGTTCCAGCCCCAGCACAGACTTCAGAGGAGCTAAGCTGCACACTTCCAGGCCTCTGCTGTCAGGCAGCTGAGAATCTGACTGC
CTCTCCTCCCCTATTACAATTCATGTTTAAAGTCATAGTCGCCCAGGAAAGAAAATAGAGAGGGGCACACTTTGTGTGTGTACCTAGTAC
ATAAGAAAGTAGAAGGAATCAGCTGGGTTTGGGGGTTGCCTTTTGTTTTGGGGCAGGTCTGGGTTTTTGTTTTGGGAGGGGGTGGGGGGA

>66648_66648_6_PMM2-RBFOX1_PMM2_chr16_8906963_ENST00000537352_RBFOX1_chr16_7568149_ENST00000422070_length(amino acids)=461AA_BP=88
MLNVSPIGRSCSQEERIEFYELDKKENIRQKFVADLRKEFAGKGLTFSIGGQISFDVFPDGWDKRYCLRHVENDGYKTIYFFGDKTMPGN
QEAAAAPDTMAQPYASAQFAPPQNGIPAEYTAPHPHPAPEYTGQTTVPEHTLNLYPPAQTHSEQSPADTSAQTVSGTATQTDDAAPTDGQ
PQTQPSENTENKSQPKRLHVSNIPFRFRDPDLRQMFGQFGKILDVEIIFNERGSKGFGFVTFENSADADRAREKLHGTVVEGRKIEVNNA
TARVMTNKKTVNPYTNGWKLNPVVGAVYSPEFYAGTVLLCQANQEGSSMYSAPSSLVYTSAMPGFPYPAATAAAAYRGAHLRGRGRTVYN
TFRAAAPPPPIPAYGGVVYQDGFYGADIYGGYAAYRYAQPTPATAAAYSDSYGRVYAADPYHHALAPAPTYGVGAMPQGSSPSTDFRGAK

--------------------------------------------------------------
>66648_66648_7_PMM2-RBFOX1_PMM2_chr16_8906963_ENST00000537352_RBFOX1_chr16_7568149_ENST00000535565_length(transcript)=1629nt_BP=486nt
GCTAGAAACTGGGGACATGGCAGCGCCTGGCCCAGCGCTCTGCCTCTTCGACGTGGATGGGACCCTCACCGCCCCGCGGCAGAAAATTAC
CAAAGAAATGGATGACTTCCTACAAAAATTGAGGCAGAAGATCAAAATCGGAGTGGTAGGCGGATCGGACTTTGAGAAAGTGCAGGAGCA
ACTGGGAAATGATGGGGTACTTTCATTGAATTCCGAAATGGGATGTTAAACGTGTCCCCTATTGGAAGAAGCTGCAGCCAAGAAGAACGC
ATTGAGTTCTACGAACTCGATAAAAAAGAAAATATAAGACAAAAGTTTGTAGCAGATCTACGGAAAGAGTTTGCTGGAAAAGGCCTCACG
TTTTCCATAGGAGGCCAGATCAGCTTTGATGTCTTTCCTGATGGATGGGACAAGAGATACTGTCTGCGACATGTGGAAAATGACGGTTAT
AAGACCATTTATTTCTTTGGAGACAAAACTATGCCAGGTAATCAGGAAGCAGCCGCTGCCCCTGACACAATGGCTCAGCCTTACGCTTCG
GCCCAGTTTGCTCCCCCGCAGAACGGTATCCCCGCGGAATACACGGCCCCTCATCCCCACCCCGCGCCAGAGTACACAGGCCAGACCACG
GTTCCCGAGCACACATTAAACCTGTACCCTCCCGCCCAGACGCACTCCGAGCAGAGCCCGGCGGACACGAGCGCTCAGACCGTCTCTGGC
ACCGCCACACAATTTGGTAAAATCTTAGATGTTGAAATTATTTTTAATGAGCGAGGCTCAAAGGTAAATAATGCCACAGCACGTGTAATG
ACAAATAAAAAGACCGTCAACCCTTATACAAATGGCTGGAAATTGAATCCAGTTGTGGGTGCAGTCTACAGTCCCGAATTCTATGCAGGC
ACGGTCCTGTTGTGCCAGGCCAACCAGGAGGGATCTTCCATGTACAGTGCCCCCAGTTCACTTGTATATACTTCTGCAATGCCAGGCTTC
CCGTATCCAGCAGCCACCGCCGCGGCCGCCTACCGAGGGGCGCACCTGCGAGGCCGCGGTCGCACCGTGTACAACACCTTCAGGGCCGCG
GCGCCCCCGCCCCCGATCCCGGCCTACGGCGGTGTTGTTTACCAGGATGGATTTTATGGTGCAGACATTTATGGTGGTTATGCTGCATAC
CGCTACGCCCAGCCTACCCCTGCCACTGCCGCTGCCTACAGTGACAGAAATCAGTTCGTCTTCGTTGCAGCAGATGAAATTTCTTGTAAC
ACCTCTGCAGTTACGGACGAGTTTATGCTGCCGACCCCTACCACCACGCACTTGCTCCAGCCCCCACCTACGGCGTTGGTGCCATGCCCC
AAGGTTCCAGCCCCAGCACAGACTTCAGAGGAGCTAAGCTGCACACTTCCAGGCCTCTGCTGTCAGGCAGCTGAGAATCTGACTGCCTCT
CCTCCCCTATTACAATTCATGTTTAAAGTCATAGTCGCCCAGGAAAGAAAATAGAGAGGGGCACACTTTGTGTGTGTACCTAGTACATAA
GAAAGTAGAAGGAATCAGCTGGGTTTGGGGGTTGCCTTTTGTTTTGGGGCAGGTCTGGGTTTTTGTTTTGGGAGGGGGTGGGGGGAGGGT

>66648_66648_7_PMM2-RBFOX1_PMM2_chr16_8906963_ENST00000537352_RBFOX1_chr16_7568149_ENST00000535565_length(amino acids)=423AA_BP=88
MLNVSPIGRSCSQEERIEFYELDKKENIRQKFVADLRKEFAGKGLTFSIGGQISFDVFPDGWDKRYCLRHVENDGYKTIYFFGDKTMPGN
QEAAAAPDTMAQPYASAQFAPPQNGIPAEYTAPHPHPAPEYTGQTTVPEHTLNLYPPAQTHSEQSPADTSAQTVSGTATQFGKILDVEII
FNERGSKVNNATARVMTNKKTVNPYTNGWKLNPVVGAVYSPEFYAGTVLLCQANQEGSSMYSAPSSLVYTSAMPGFPYPAATAAAAYRGA
HLRGRGRTVYNTFRAAAPPPPIPAYGGVVYQDGFYGADIYGGYAAYRYAQPTPATAAAYSDRNQFVFVAADEISCNTSAVTDEFMLPTPT

--------------------------------------------------------------
>66648_66648_8_PMM2-RBFOX1_PMM2_chr16_8906963_ENST00000537352_RBFOX1_chr16_7568149_ENST00000547372_length(transcript)=3548nt_BP=486nt
GCTAGAAACTGGGGACATGGCAGCGCCTGGCCCAGCGCTCTGCCTCTTCGACGTGGATGGGACCCTCACCGCCCCGCGGCAGAAAATTAC
CAAAGAAATGGATGACTTCCTACAAAAATTGAGGCAGAAGATCAAAATCGGAGTGGTAGGCGGATCGGACTTTGAGAAAGTGCAGGAGCA
ACTGGGAAATGATGGGGTACTTTCATTGAATTCCGAAATGGGATGTTAAACGTGTCCCCTATTGGAAGAAGCTGCAGCCAAGAAGAACGC
ATTGAGTTCTACGAACTCGATAAAAAAGAAAATATAAGACAAAAGTTTGTAGCAGATCTACGGAAAGAGTTTGCTGGAAAAGGCCTCACG
TTTTCCATAGGAGGCCAGATCAGCTTTGATGTCTTTCCTGATGGATGGGACAAGAGATACTGTCTGCGACATGTGGAAAATGACGGTTAT
AAGACCATTTATTTCTTTGGAGACAAAACTATGCCAGGTAATCAGGAAGCAGCCGCTGCCCCTGACACAATGGCTCAGCCTTACGCTTCG
GCCCAGTTTGCTCCCCCGCAGAACGGTATCCCCGCGGAATACACGGCCCCTCATCCCCACCCCGCGCCAGAGTACACAGGCCAGACCACG
GTTCCCGAGCACACATTAAACCTGTACCCTCCCGCCCAGACGCACTCCGAGCAGAGCCCGGCGGACACGAGCGCTCAGACCGTCTCTGGC
ACCGCCACACAGACAGATGACGCAGCACCGACGGATGGCCAGCCCCAGACACAACCTTCTGAAAACACGGAAAACAAGTCTCAGCCCAAG
CGGCTGCATGTCTCCAATATCCCCTTCAGGTTCCGGGATCCGGACCTCAGACAAATGTTTGGTCAATTTGGTAAAATCTTAGATGTTGAA
ATTATTTTTAATGAGCGAGGCTCAAAGGGATTTGGTTTCGTAACTTTCGAAAATAGTGCCGATGCGGACAGGGCGAGGGAGAAATTACAC
GGCACCGTGGTAGAGGGCCGTAAAATCGAGGTAAATAATGCCACAGCACGTGTAATGACAAATAAAAAGACCGTCAACCCTTATACAAAT
GGCTGGAAATTGAATCCAGTTGTGGGTGCAGTCTACAGTCCCGAATTCTATGCAGGCACGGTCCTGTTGTGCCAGGCCAACCAGGAGGGA
TCTTCCATGTACAGTGCCCCCAGTTCACTTGTATATACTTCTGCAATGCCAGGCTTCCCGTATCCAGCAGCCACCGCCGCGGCCGCCTAC
CGAGGGGCGCACCTGCGAGGCCGCGGTCGCACCGTGTACAACACCTTCAGGGCCGCGGCGCCCCCGCCCCCGATCCCGGCCTACGGCGGT
GTTGTTTACCAGGATGGATTTTATGGTGCAGACATTTATGGTGGTTATGCTGCATACCGCTACGCCCAGCCTACCCCTGCCACTGCCGCT
GCCTACAGTGACAGAAATCAGTTCGTCTTCGTTGCAGCAGATGAAATTTCTTGTAACACCTCTGCAGTTACGGACGAGTTTATGCTGCCG
ACCCCTACCACCACGCACTTGCTCCAGCCCCCACCTACGGCGTTGGTGCCATGCCCCAAGGTTCCAGCCCCAGCACAGACTTCAGAGGAG
CTAAGCTGCACACTTCCAGGCCTCTGCTGTCAGGCAGCTGAGAATCTGACTGCCTCTCCTCCCCTATTACAATTCATGTTTAAAGTCATA
GTCGCCCAGGAAAGAAAATAGAGAGGGGCACACTTTGTGTGTGTACCTAGTACATAAGAAAGTAGAAGGAATCAGCTGGGTTTGGGGGTT
GCCTTTTGTTTTGGGGCAGGTCTGGGTTTTTGTTTTGGGAGGGGGTGGGGGGAGGGTAAAAAATGGGAGGTAAGGGTGGGGTGAACTTGC
CTGTACTTGTTCAAACTTCTATGCACTGAAACTCTTGAGTACAGTAAGACGTGCCCATCACGTGAGAGCATATGCAATCATTACAAAGCT
TTGGCATGCAGTTTTCTGCTTGGATCAAGAATATCAGTCCTTACCCTAAAAATGAATCCCCATAGGCATTCATTTGAATTGCCAATACTT
TTAGAAAAAGGAAATCGTTAAGTGCCACCTTGTAGCCATTAAAACCATGGCCGGACAGTTCACTGAAGCTCAGTCATAGAAATTCAGCCA
TGATTTGGAAGCATTGTTTTGCACAAGCTTAATTACATCAAGCAATTCATCTGTACAACTCCACAACTCCCTTCTCAAGATCAGATTCCA
TACAGCTTACAGAGCCAAGTTAAGTAAGAAGTAGGTTGAGATTTTCATCCCAATTCTGCATTCAACAACTCTGCTTCAACACCTAGTCCA
CATGAGGAATGTGTTGGAGAGTTGAATTACATTCAACAACTGGTCCAAATTCAACCTCAAGTGCAGATTATTCTGTTATAAAAAAATGAG
ACAGTGAAAATCCTTCCATTGTCCAGCTTATAATAGAGTCCTTTTAGCTAAGAGGACTGGCTGACAGAATTTGGTTTTGCAGGGAATTTC
TTTAGGAGGAGCTATTGGGGAAGGTCAGGAATGGCCCTATCTTTAGTTCTCCAAGAATGACCTGGGATGGGTAGGGGGTGCCTCCATTTC
GGTTGGTTTTGAGTGTCTATTTTTCACATTAGTCTTTTTGATGATCCACATGTTGCAAAAGGAAAATGTAAAAAACACACCCCTCAAATT
GCTTTGTTTCAGAATGCTTTTGCACCTTTGACTGATGCCAAGACTAGGAGCCATGCTGATGATGTGGGTCTCGTTCTTTCTTCATTGCAG
GCTAGTATATACCGAGGGGGATACAACCGTTTTGCTCCATACTAAATGACAAAACCATAAAAACCTTCCAATGTGGGGAGAAAGGAAGCT
TTCCGAGGCCTGAGTATTGCAATACATGCAGTAGTACATCATTTTAGCAACTCTAAAAAAAAAAAAAATACAAATAAAAAGGAAAAAAAA
TTACATTTTTTATCTTATACCTCAGATATTTTGTTCTGTGTATTTTAATATTGTGGGTCTTTAATTTCTGAAGGTTCCGTAGTTTGGTTG
CTGGCTGTAGGAGTTTTTGTGGTTGATCTAGACAGATGCTAGATAATGAATAAAAACTGGTTTAGGGCCATATCCAGAGTGCTATATTAT
GTAAATGAATTATATATGCTGAATATTAAGCTACTGGGGTTATCAGCTATTTGGGAAGAGTGTAAGTGACTACAGTAGTCATTTTTTTCT
GCACCTGCATTATTTTATTTTGCGAAAGGGGAGGTTGGGAGGGGCTTAGGGGATTGGAACTGGGGTTTGGCTGAAAGAAAAAAAAAAAAA
TGTAACTGATGAATCTAAACGACCCACTGCACCAACAATCATTTATCAATGGTTCTAAGTTACTCATTGCCAGTTCAAGCCAAAGGTCAT
GTTGTTAAGGGGGTGCTTCTAGTAGCACTTGTGCATCTGAGTTGAATGAAGCTGTGCAAACCCACCCTTTAAACCATTCCACCCGGCAGT

>66648_66648_8_PMM2-RBFOX1_PMM2_chr16_8906963_ENST00000537352_RBFOX1_chr16_7568149_ENST00000547372_length(amino acids)=502AA_BP=88
MLNVSPIGRSCSQEERIEFYELDKKENIRQKFVADLRKEFAGKGLTFSIGGQISFDVFPDGWDKRYCLRHVENDGYKTIYFFGDKTMPGN
QEAAAAPDTMAQPYASAQFAPPQNGIPAEYTAPHPHPAPEYTGQTTVPEHTLNLYPPAQTHSEQSPADTSAQTVSGTATQTDDAAPTDGQ
PQTQPSENTENKSQPKRLHVSNIPFRFRDPDLRQMFGQFGKILDVEIIFNERGSKGFGFVTFENSADADRAREKLHGTVVEGRKIEVNNA
TARVMTNKKTVNPYTNGWKLNPVVGAVYSPEFYAGTVLLCQANQEGSSMYSAPSSLVYTSAMPGFPYPAATAAAAYRGAHLRGRGRTVYN
TFRAAAPPPPIPAYGGVVYQDGFYGADIYGGYAAYRYAQPTPATAAAYSDRNQFVFVAADEISCNTSAVTDEFMLPTPTTTHLLQPPPTA

--------------------------------------------------------------
>66648_66648_9_PMM2-RBFOX1_PMM2_chr16_8906963_ENST00000537352_RBFOX1_chr16_7568149_ENST00000550418_length(transcript)=1748nt_BP=486nt
GCTAGAAACTGGGGACATGGCAGCGCCTGGCCCAGCGCTCTGCCTCTTCGACGTGGATGGGACCCTCACCGCCCCGCGGCAGAAAATTAC
CAAAGAAATGGATGACTTCCTACAAAAATTGAGGCAGAAGATCAAAATCGGAGTGGTAGGCGGATCGGACTTTGAGAAAGTGCAGGAGCA
ACTGGGAAATGATGGGGTACTTTCATTGAATTCCGAAATGGGATGTTAAACGTGTCCCCTATTGGAAGAAGCTGCAGCCAAGAAGAACGC
ATTGAGTTCTACGAACTCGATAAAAAAGAAAATATAAGACAAAAGTTTGTAGCAGATCTACGGAAAGAGTTTGCTGGAAAAGGCCTCACG
TTTTCCATAGGAGGCCAGATCAGCTTTGATGTCTTTCCTGATGGATGGGACAAGAGATACTGTCTGCGACATGTGGAAAATGACGGTTAT
AAGACCATTTATTTCTTTGGAGACAAAACTATGCCAGGTAATCAGGAAGCAGCCGCTGCCCCTGACACAATGGCTCAGCCTTACGCTTCG
GCCCAGTTTGCTCCCCCGCAGAACGGTATCCCCGCGGAATACACGGCCCCTCATCCCCACCCCGCGCCAGAGTACACAGGCCAGACCACG
GTTCCCGAGCACACATTAAACCTGTACCCTCCCGCCCAGACGCACTCCGAGCAGAGCCCGGCGGACACGAGCGCTCAGACCGTCTCTGGC
ACCGCCACACAGACAGATGACGCAGCACCGACGGATGGCCAGCCCCAGACACAACCTTCTGAAAACACGGAAAACAAGTCTCAGCCCAAG
CGGCTGCATGTCTCCAATATCCCCTTCAGGTTCCGGGATCCGGACCTCAGACAAATGTTTGGTCAATTTGGTAAAATCTTAGATGTTGAA
ATTATTTTTAATGAGCGAGGCTCAAAGGGATTTGGTTTCGTAACTTTCGAAAATAGTGCCGATGCGGACAGGGCGAGGGAGAAATTACAC
GGCACCGTGGTAGAGGGCCGTAAAATCGAGGTAAATAATGCCACAGCACGTGTAATGACAAATAAAAAGACCGTCAACCCTTATACAAAT
GGCTGGAAATTGAATCCAGTTGTGGGTGCAGTCTACAGTCCCGAATTCTATGCAGGCACGGTCCTGTTGTGCCAGGCCAACCAGGAGGGA
TCTTCCATGTACAGTGCCCCCAGTTCACTTGTATATACTTCTGCAATGCCAGGCTTCCCGTATCCAGCAGCCACCGCCGCGGCCGCCTAC
CGAGGGGCGCACCTGCGAGGCCGCGGTCGCACCGTGTACAACACCTTCAGGGCCGCGGCGCCCCCGCCCCCGATCCCGGCCTACGGCGGT
GTTGTTTACCAGGATGGATTTTATGGTGCAGACATTTATGGTGGTTATGCTGCATACCGCTACGCCCAGCCTACCCCTGCCACTGCCGCT
GCCTACAGTGACAGTTACGGACGAGTTTATGCTGCCGACCCCTACCACCACGCACTTGCTCCAGCCCCCACCTACGGCGTTGGTGCCATG
AATGCTTTTGCACCTTTGACTGATGCCAAGACTAGGAGCCATGCTGATGATGTGGGTCTCGTTCTTTCTTCATTGCAGGCTAGTATATAC
CGAGGGGGATACAACCGTTTTGCTCCATACTAAATGACAAAACCATAAAAACCTTCCAATGTGGGGAGAAAGGAAGCTTTCCGAGGCCTG

>66648_66648_9_PMM2-RBFOX1_PMM2_chr16_8906963_ENST00000537352_RBFOX1_chr16_7568149_ENST00000550418_length(amino acids)=476AA_BP=88
MLNVSPIGRSCSQEERIEFYELDKKENIRQKFVADLRKEFAGKGLTFSIGGQISFDVFPDGWDKRYCLRHVENDGYKTIYFFGDKTMPGN
QEAAAAPDTMAQPYASAQFAPPQNGIPAEYTAPHPHPAPEYTGQTTVPEHTLNLYPPAQTHSEQSPADTSAQTVSGTATQTDDAAPTDGQ
PQTQPSENTENKSQPKRLHVSNIPFRFRDPDLRQMFGQFGKILDVEIIFNERGSKGFGFVTFENSADADRAREKLHGTVVEGRKIEVNNA
TARVMTNKKTVNPYTNGWKLNPVVGAVYSPEFYAGTVLLCQANQEGSSMYSAPSSLVYTSAMPGFPYPAATAAAAYRGAHLRGRGRTVYN
TFRAAAPPPPIPAYGGVVYQDGFYGADIYGGYAAYRYAQPTPATAAAYSDSYGRVYAADPYHHALAPAPTYGVGAMNAFAPLTDAKTRSH

--------------------------------------------------------------
>66648_66648_10_PMM2-RBFOX1_PMM2_chr16_8906963_ENST00000537352_RBFOX1_chr16_7568149_ENST00000553186_length(transcript)=1667nt_BP=486nt
GCTAGAAACTGGGGACATGGCAGCGCCTGGCCCAGCGCTCTGCCTCTTCGACGTGGATGGGACCCTCACCGCCCCGCGGCAGAAAATTAC
CAAAGAAATGGATGACTTCCTACAAAAATTGAGGCAGAAGATCAAAATCGGAGTGGTAGGCGGATCGGACTTTGAGAAAGTGCAGGAGCA
ACTGGGAAATGATGGGGTACTTTCATTGAATTCCGAAATGGGATGTTAAACGTGTCCCCTATTGGAAGAAGCTGCAGCCAAGAAGAACGC
ATTGAGTTCTACGAACTCGATAAAAAAGAAAATATAAGACAAAAGTTTGTAGCAGATCTACGGAAAGAGTTTGCTGGAAAAGGCCTCACG
TTTTCCATAGGAGGCCAGATCAGCTTTGATGTCTTTCCTGATGGATGGGACAAGAGATACTGTCTGCGACATGTGGAAAATGACGGTTAT
AAGACCATTTATTTCTTTGGAGACAAAACTATGCCAGGTAATCAGGAAGCAGCCGCTGCCCCTGACACAATGGCTCAGCCTTACGCTTCG
GCCCAGTTTGCTCCCCCGCAGAACGGTATCCCCGCGGAATACACGGCCCCTCATCCCCACCCCGCGCCAGAGTACACAGGCCAGACCACG
GTTCCCGAGCACACATTAAACCTGTACCCTCCCGCCCAGACGCACTCCGAGCAGAGCCCGGCGGACACGAGCGCTCAGACCGTCTCTGGC
ACCGCCACACAGACAGATGACGCAGCACCGACGGATGGCCAGCCCCAGACACAACCTTCTGAAAACACGGAAAACAAGTCTCAGCCCAAG
CGGCTGCATGTCTCCAATATCCCCTTCAGGTTCCGGGATCCGGACCTCAGACAAATGTTTGGTCAATTTGGTAAAATCTTAGATGTTGAA
ATTATTTTTAATGAGCGAGGCTCAAAGGGATTTGGTTTCGTAACTTTCGAAAATAGTGCCGATGCGGACAGGGCGAGGGAGAAATTACAC
GGCACCGTGGTAGAGGGCCGTAAAATCGAGGTAAATAATGCCACAGCACGTGTAATGACAAATAAAAAGACCGTCAACCCTTATACAAAT
GGCTGGAAATTGAATCCAGTTGTGGGTGCAGTCTACAGTCCCGAATTCTATGCAGTGCCAGGCTTCCCGTATCCAGCAGCCACCGCCGCG
GCCGCCTACCGAGGGGCGCACCTGCGAGGCCGCGGTCGCACCGTGTACAACACCTTCAGGGCCGCGGCGCCCCCGCCCCCGATCCCGGCC
TACGGCGGTGTTGTTTACCAGGATGGATTTTATGGTGCAGACATTTATGGTGGTTATGCTGCATACCGCTACGCCCAGCCTACCCCTGCC
ACTGCCGCTGCCTACAGTGACAGTTACGGACGAGTTTATGCTGCCGACCCCTACCACCACGCACTTGCTCCAGCCCCCACCTACGGCGTT
GGTGCCATGAATGCTTTTGCACCTTTGACTGATGCCAAGACTAGGAGCCATGCTGATGATGTGGGTCTCGTTCTTTCTTCATTGCAGGCT
AGTATATACCGAGGGGGATACAACCGTTTTGCTCCATACTAAATGACAAAACCATAAAAACCTTCCAATGTGGGGAGAAAGGAAGCTTTC

>66648_66648_10_PMM2-RBFOX1_PMM2_chr16_8906963_ENST00000537352_RBFOX1_chr16_7568149_ENST00000553186_length(amino acids)=449AA_BP=88
MLNVSPIGRSCSQEERIEFYELDKKENIRQKFVADLRKEFAGKGLTFSIGGQISFDVFPDGWDKRYCLRHVENDGYKTIYFFGDKTMPGN
QEAAAAPDTMAQPYASAQFAPPQNGIPAEYTAPHPHPAPEYTGQTTVPEHTLNLYPPAQTHSEQSPADTSAQTVSGTATQTDDAAPTDGQ
PQTQPSENTENKSQPKRLHVSNIPFRFRDPDLRQMFGQFGKILDVEIIFNERGSKGFGFVTFENSADADRAREKLHGTVVEGRKIEVNNA
TARVMTNKKTVNPYTNGWKLNPVVGAVYSPEFYAVPGFPYPAATAAAAYRGAHLRGRGRTVYNTFRAAAPPPPIPAYGGVVYQDGFYGAD

--------------------------------------------------------------
>66648_66648_11_PMM2-RBFOX1_PMM2_chr16_8906963_ENST00000539622_RBFOX1_chr16_7568149_ENST00000422070_length(transcript)=1935nt_BP=603nt
GTGCCAACGTGTCTTGTAAGGTGCGGCTAGAAACTGGGGACATGGCAGCGCCTGGCCCAGCGCTCTGCCTCTTCGACGTGGATGGGACCC
TCACCGCCCCGCGGCAGAAAATTACCAAAGAAATGGATGACTTCCTACAAAAATTGAGGCAGAAGATCAAAATCGGAGTGGTAGGCGGAT
CGGACTTTGAGAAAGTGCAGGAGCAACTGGGAAATGATGAATATTCAAAGTCATCTGGGTGAGGCCCTAATCCAAGATTTAATCAACTAC
TGTCTGAGCTACATTGCGAAAATTAAACTCCCGAAGAAGAGGGGTACTTTCATTGAATTCCGAAATGGGATGTTAAACGTGTCCCCTATT
GGAAGAAGCTGCAGCCAAGAAGAACGCATTGAGTTCTACGAACTCGATAAAAAAGAAAATATAAGACAAAAGTTTGTAGCAGATCTACGG
AAAGAGTTTGCTGGAAAAGGCCTCACGTTTTCCATAGGAGGCCAGATCAGCTTTGATGTCTTTCCTGATGGATGGGACAAGAGATACTGT
CTGCGACATGTGGAAAATGACGGTTATAAGACCATTTATTTCTTTGGAGACAAAACTATGCCAGGTAATCAGGAAGCAGCCGCTGCCCCT
GACACAATGGCTCAGCCTTACGCTTCGGCCCAGTTTGCTCCCCCGCAGAACGGTATCCCCGCGGAATACACGGCCCCTCATCCCCACCCC
GCGCCAGAGTACACAGGCCAGACCACGGTTCCCGAGCACACATTAAACCTGTACCCTCCCGCCCAGACGCACTCCGAGCAGAGCCCGGCG
GACACGAGCGCTCAGACCGTCTCTGGCACCGCCACACAGACAGATGACGCAGCACCGACGGATGGCCAGCCCCAGACACAACCTTCTGAA
AACACGGAAAACAAGTCTCAGCCCAAGCGGCTGCATGTCTCCAATATCCCCTTCAGGTTCCGGGATCCGGACCTCAGACAAATGTTTGGT
CAATTTGGTAAAATCTTAGATGTTGAAATTATTTTTAATGAGCGAGGCTCAAAGGGATTTGGTTTCGTAACTTTCGAAAATAGTGCCGAT
GCGGACAGGGCGAGGGAGAAATTACACGGCACCGTGGTAGAGGGCCGTAAAATCGAGGTAAATAATGCCACAGCACGTGTAATGACAAAT
AAAAAGACCGTCAACCCTTATACAAATGGCTGGAAATTGAATCCAGTTGTGGGTGCAGTCTACAGTCCCGAATTCTATGCAGGCACGGTC
CTGTTGTGCCAGGCCAACCAGGAGGGATCTTCCATGTACAGTGCCCCCAGTTCACTTGTATATACTTCTGCAATGCCAGGCTTCCCGTAT
CCAGCAGCCACCGCCGCGGCCGCCTACCGAGGGGCGCACCTGCGAGGCCGCGGTCGCACCGTGTACAACACCTTCAGGGCCGCGGCGCCC
CCGCCCCCGATCCCGGCCTACGGCGGTGTTGTTTACCAGGATGGATTTTATGGTGCAGACATTTATGGTGGTTATGCTGCATACCGCTAC
GCCCAGCCTACCCCTGCCACTGCCGCTGCCTACAGTGACAGTTACGGACGAGTTTATGCTGCCGACCCCTACCACCACGCACTTGCTCCA
GCCCCCACCTACGGCGTTGGTGCCATGCCCCAAGGTTCCAGCCCCAGCACAGACTTCAGAGGAGCTAAGCTGCACACTTCCAGGCCTCTG
CTGTCAGGCAGCTGAGAATCTGACTGCCTCTCCTCCCCTATTACAATTCATGTTTAAAGTCATAGTCGCCCAGGAAAGAAAATAGAGAGG
GGCACACTTTGTGTGTGTACCTAGTACATAAGAAAGTAGAAGGAATCAGCTGGGTTTGGGGGTTGCCTTTTGTTTTGGGGCAGGTCTGGG

>66648_66648_11_PMM2-RBFOX1_PMM2_chr16_8906963_ENST00000539622_RBFOX1_chr16_7568149_ENST00000422070_length(amino acids)=512AA_BP=139
MRKCRSNWEMMNIQSHLGEALIQDLINYCLSYIAKIKLPKKRGTFIEFRNGMLNVSPIGRSCSQEERIEFYELDKKENIRQKFVADLRKE
FAGKGLTFSIGGQISFDVFPDGWDKRYCLRHVENDGYKTIYFFGDKTMPGNQEAAAAPDTMAQPYASAQFAPPQNGIPAEYTAPHPHPAP
EYTGQTTVPEHTLNLYPPAQTHSEQSPADTSAQTVSGTATQTDDAAPTDGQPQTQPSENTENKSQPKRLHVSNIPFRFRDPDLRQMFGQF
GKILDVEIIFNERGSKGFGFVTFENSADADRAREKLHGTVVEGRKIEVNNATARVMTNKKTVNPYTNGWKLNPVVGAVYSPEFYAGTVLL
CQANQEGSSMYSAPSSLVYTSAMPGFPYPAATAAAAYRGAHLRGRGRTVYNTFRAAAPPPPIPAYGGVVYQDGFYGADIYGGYAAYRYAQ

--------------------------------------------------------------
>66648_66648_12_PMM2-RBFOX1_PMM2_chr16_8906963_ENST00000539622_RBFOX1_chr16_7568149_ENST00000535565_length(transcript)=1746nt_BP=603nt
GTGCCAACGTGTCTTGTAAGGTGCGGCTAGAAACTGGGGACATGGCAGCGCCTGGCCCAGCGCTCTGCCTCTTCGACGTGGATGGGACCC
TCACCGCCCCGCGGCAGAAAATTACCAAAGAAATGGATGACTTCCTACAAAAATTGAGGCAGAAGATCAAAATCGGAGTGGTAGGCGGAT
CGGACTTTGAGAAAGTGCAGGAGCAACTGGGAAATGATGAATATTCAAAGTCATCTGGGTGAGGCCCTAATCCAAGATTTAATCAACTAC
TGTCTGAGCTACATTGCGAAAATTAAACTCCCGAAGAAGAGGGGTACTTTCATTGAATTCCGAAATGGGATGTTAAACGTGTCCCCTATT
GGAAGAAGCTGCAGCCAAGAAGAACGCATTGAGTTCTACGAACTCGATAAAAAAGAAAATATAAGACAAAAGTTTGTAGCAGATCTACGG
AAAGAGTTTGCTGGAAAAGGCCTCACGTTTTCCATAGGAGGCCAGATCAGCTTTGATGTCTTTCCTGATGGATGGGACAAGAGATACTGT
CTGCGACATGTGGAAAATGACGGTTATAAGACCATTTATTTCTTTGGAGACAAAACTATGCCAGGTAATCAGGAAGCAGCCGCTGCCCCT
GACACAATGGCTCAGCCTTACGCTTCGGCCCAGTTTGCTCCCCCGCAGAACGGTATCCCCGCGGAATACACGGCCCCTCATCCCCACCCC
GCGCCAGAGTACACAGGCCAGACCACGGTTCCCGAGCACACATTAAACCTGTACCCTCCCGCCCAGACGCACTCCGAGCAGAGCCCGGCG
GACACGAGCGCTCAGACCGTCTCTGGCACCGCCACACAATTTGGTAAAATCTTAGATGTTGAAATTATTTTTAATGAGCGAGGCTCAAAG
GTAAATAATGCCACAGCACGTGTAATGACAAATAAAAAGACCGTCAACCCTTATACAAATGGCTGGAAATTGAATCCAGTTGTGGGTGCA
GTCTACAGTCCCGAATTCTATGCAGGCACGGTCCTGTTGTGCCAGGCCAACCAGGAGGGATCTTCCATGTACAGTGCCCCCAGTTCACTT
GTATATACTTCTGCAATGCCAGGCTTCCCGTATCCAGCAGCCACCGCCGCGGCCGCCTACCGAGGGGCGCACCTGCGAGGCCGCGGTCGC
ACCGTGTACAACACCTTCAGGGCCGCGGCGCCCCCGCCCCCGATCCCGGCCTACGGCGGTGTTGTTTACCAGGATGGATTTTATGGTGCA
GACATTTATGGTGGTTATGCTGCATACCGCTACGCCCAGCCTACCCCTGCCACTGCCGCTGCCTACAGTGACAGAAATCAGTTCGTCTTC
GTTGCAGCAGATGAAATTTCTTGTAACACCTCTGCAGTTACGGACGAGTTTATGCTGCCGACCCCTACCACCACGCACTTGCTCCAGCCC
CCACCTACGGCGTTGGTGCCATGCCCCAAGGTTCCAGCCCCAGCACAGACTTCAGAGGAGCTAAGCTGCACACTTCCAGGCCTCTGCTGT
CAGGCAGCTGAGAATCTGACTGCCTCTCCTCCCCTATTACAATTCATGTTTAAAGTCATAGTCGCCCAGGAAAGAAAATAGAGAGGGGCA
CACTTTGTGTGTGTACCTAGTACATAAGAAAGTAGAAGGAATCAGCTGGGTTTGGGGGTTGCCTTTTGTTTTGGGGCAGGTCTGGGTTTT

>66648_66648_12_PMM2-RBFOX1_PMM2_chr16_8906963_ENST00000539622_RBFOX1_chr16_7568149_ENST00000535565_length(amino acids)=474AA_BP=139
MRKCRSNWEMMNIQSHLGEALIQDLINYCLSYIAKIKLPKKRGTFIEFRNGMLNVSPIGRSCSQEERIEFYELDKKENIRQKFVADLRKE
FAGKGLTFSIGGQISFDVFPDGWDKRYCLRHVENDGYKTIYFFGDKTMPGNQEAAAAPDTMAQPYASAQFAPPQNGIPAEYTAPHPHPAP
EYTGQTTVPEHTLNLYPPAQTHSEQSPADTSAQTVSGTATQFGKILDVEIIFNERGSKVNNATARVMTNKKTVNPYTNGWKLNPVVGAVY
SPEFYAGTVLLCQANQEGSSMYSAPSSLVYTSAMPGFPYPAATAAAAYRGAHLRGRGRTVYNTFRAAAPPPPIPAYGGVVYQDGFYGADI
YGGYAAYRYAQPTPATAAAYSDRNQFVFVAADEISCNTSAVTDEFMLPTPTTTHLLQPPPTALVPCPKVPAPAQTSEELSCTLPGLCCQA

--------------------------------------------------------------
>66648_66648_13_PMM2-RBFOX1_PMM2_chr16_8906963_ENST00000539622_RBFOX1_chr16_7568149_ENST00000547372_length(transcript)=3665nt_BP=603nt
GTGCCAACGTGTCTTGTAAGGTGCGGCTAGAAACTGGGGACATGGCAGCGCCTGGCCCAGCGCTCTGCCTCTTCGACGTGGATGGGACCC
TCACCGCCCCGCGGCAGAAAATTACCAAAGAAATGGATGACTTCCTACAAAAATTGAGGCAGAAGATCAAAATCGGAGTGGTAGGCGGAT
CGGACTTTGAGAAAGTGCAGGAGCAACTGGGAAATGATGAATATTCAAAGTCATCTGGGTGAGGCCCTAATCCAAGATTTAATCAACTAC
TGTCTGAGCTACATTGCGAAAATTAAACTCCCGAAGAAGAGGGGTACTTTCATTGAATTCCGAAATGGGATGTTAAACGTGTCCCCTATT
GGAAGAAGCTGCAGCCAAGAAGAACGCATTGAGTTCTACGAACTCGATAAAAAAGAAAATATAAGACAAAAGTTTGTAGCAGATCTACGG
AAAGAGTTTGCTGGAAAAGGCCTCACGTTTTCCATAGGAGGCCAGATCAGCTTTGATGTCTTTCCTGATGGATGGGACAAGAGATACTGT
CTGCGACATGTGGAAAATGACGGTTATAAGACCATTTATTTCTTTGGAGACAAAACTATGCCAGGTAATCAGGAAGCAGCCGCTGCCCCT
GACACAATGGCTCAGCCTTACGCTTCGGCCCAGTTTGCTCCCCCGCAGAACGGTATCCCCGCGGAATACACGGCCCCTCATCCCCACCCC
GCGCCAGAGTACACAGGCCAGACCACGGTTCCCGAGCACACATTAAACCTGTACCCTCCCGCCCAGACGCACTCCGAGCAGAGCCCGGCG
GACACGAGCGCTCAGACCGTCTCTGGCACCGCCACACAGACAGATGACGCAGCACCGACGGATGGCCAGCCCCAGACACAACCTTCTGAA
AACACGGAAAACAAGTCTCAGCCCAAGCGGCTGCATGTCTCCAATATCCCCTTCAGGTTCCGGGATCCGGACCTCAGACAAATGTTTGGT
CAATTTGGTAAAATCTTAGATGTTGAAATTATTTTTAATGAGCGAGGCTCAAAGGGATTTGGTTTCGTAACTTTCGAAAATAGTGCCGAT
GCGGACAGGGCGAGGGAGAAATTACACGGCACCGTGGTAGAGGGCCGTAAAATCGAGGTAAATAATGCCACAGCACGTGTAATGACAAAT
AAAAAGACCGTCAACCCTTATACAAATGGCTGGAAATTGAATCCAGTTGTGGGTGCAGTCTACAGTCCCGAATTCTATGCAGGCACGGTC
CTGTTGTGCCAGGCCAACCAGGAGGGATCTTCCATGTACAGTGCCCCCAGTTCACTTGTATATACTTCTGCAATGCCAGGCTTCCCGTAT
CCAGCAGCCACCGCCGCGGCCGCCTACCGAGGGGCGCACCTGCGAGGCCGCGGTCGCACCGTGTACAACACCTTCAGGGCCGCGGCGCCC
CCGCCCCCGATCCCGGCCTACGGCGGTGTTGTTTACCAGGATGGATTTTATGGTGCAGACATTTATGGTGGTTATGCTGCATACCGCTAC
GCCCAGCCTACCCCTGCCACTGCCGCTGCCTACAGTGACAGAAATCAGTTCGTCTTCGTTGCAGCAGATGAAATTTCTTGTAACACCTCT
GCAGTTACGGACGAGTTTATGCTGCCGACCCCTACCACCACGCACTTGCTCCAGCCCCCACCTACGGCGTTGGTGCCATGCCCCAAGGTT
CCAGCCCCAGCACAGACTTCAGAGGAGCTAAGCTGCACACTTCCAGGCCTCTGCTGTCAGGCAGCTGAGAATCTGACTGCCTCTCCTCCC
CTATTACAATTCATGTTTAAAGTCATAGTCGCCCAGGAAAGAAAATAGAGAGGGGCACACTTTGTGTGTGTACCTAGTACATAAGAAAGT
AGAAGGAATCAGCTGGGTTTGGGGGTTGCCTTTTGTTTTGGGGCAGGTCTGGGTTTTTGTTTTGGGAGGGGGTGGGGGGAGGGTAAAAAA
TGGGAGGTAAGGGTGGGGTGAACTTGCCTGTACTTGTTCAAACTTCTATGCACTGAAACTCTTGAGTACAGTAAGACGTGCCCATCACGT
GAGAGCATATGCAATCATTACAAAGCTTTGGCATGCAGTTTTCTGCTTGGATCAAGAATATCAGTCCTTACCCTAAAAATGAATCCCCAT
AGGCATTCATTTGAATTGCCAATACTTTTAGAAAAAGGAAATCGTTAAGTGCCACCTTGTAGCCATTAAAACCATGGCCGGACAGTTCAC
TGAAGCTCAGTCATAGAAATTCAGCCATGATTTGGAAGCATTGTTTTGCACAAGCTTAATTACATCAAGCAATTCATCTGTACAACTCCA
CAACTCCCTTCTCAAGATCAGATTCCATACAGCTTACAGAGCCAAGTTAAGTAAGAAGTAGGTTGAGATTTTCATCCCAATTCTGCATTC
AACAACTCTGCTTCAACACCTAGTCCACATGAGGAATGTGTTGGAGAGTTGAATTACATTCAACAACTGGTCCAAATTCAACCTCAAGTG
CAGATTATTCTGTTATAAAAAAATGAGACAGTGAAAATCCTTCCATTGTCCAGCTTATAATAGAGTCCTTTTAGCTAAGAGGACTGGCTG
ACAGAATTTGGTTTTGCAGGGAATTTCTTTAGGAGGAGCTATTGGGGAAGGTCAGGAATGGCCCTATCTTTAGTTCTCCAAGAATGACCT
GGGATGGGTAGGGGGTGCCTCCATTTCGGTTGGTTTTGAGTGTCTATTTTTCACATTAGTCTTTTTGATGATCCACATGTTGCAAAAGGA
AAATGTAAAAAACACACCCCTCAAATTGCTTTGTTTCAGAATGCTTTTGCACCTTTGACTGATGCCAAGACTAGGAGCCATGCTGATGAT
GTGGGTCTCGTTCTTTCTTCATTGCAGGCTAGTATATACCGAGGGGGATACAACCGTTTTGCTCCATACTAAATGACAAAACCATAAAAA
CCTTCCAATGTGGGGAGAAAGGAAGCTTTCCGAGGCCTGAGTATTGCAATACATGCAGTAGTACATCATTTTAGCAACTCTAAAAAAAAA
AAAAATACAAATAAAAAGGAAAAAAAATTACATTTTTTATCTTATACCTCAGATATTTTGTTCTGTGTATTTTAATATTGTGGGTCTTTA
ATTTCTGAAGGTTCCGTAGTTTGGTTGCTGGCTGTAGGAGTTTTTGTGGTTGATCTAGACAGATGCTAGATAATGAATAAAAACTGGTTT
AGGGCCATATCCAGAGTGCTATATTATGTAAATGAATTATATATGCTGAATATTAAGCTACTGGGGTTATCAGCTATTTGGGAAGAGTGT
AAGTGACTACAGTAGTCATTTTTTTCTGCACCTGCATTATTTTATTTTGCGAAAGGGGAGGTTGGGAGGGGCTTAGGGGATTGGAACTGG
GGTTTGGCTGAAAGAAAAAAAAAAAAATGTAACTGATGAATCTAAACGACCCACTGCACCAACAATCATTTATCAATGGTTCTAAGTTAC
TCATTGCCAGTTCAAGCCAAAGGTCATGTTGTTAAGGGGGTGCTTCTAGTAGCACTTGTGCATCTGAGTTGAATGAAGCTGTGCAAACCC

>66648_66648_13_PMM2-RBFOX1_PMM2_chr16_8906963_ENST00000539622_RBFOX1_chr16_7568149_ENST00000547372_length(amino acids)=553AA_BP=139
MRKCRSNWEMMNIQSHLGEALIQDLINYCLSYIAKIKLPKKRGTFIEFRNGMLNVSPIGRSCSQEERIEFYELDKKENIRQKFVADLRKE
FAGKGLTFSIGGQISFDVFPDGWDKRYCLRHVENDGYKTIYFFGDKTMPGNQEAAAAPDTMAQPYASAQFAPPQNGIPAEYTAPHPHPAP
EYTGQTTVPEHTLNLYPPAQTHSEQSPADTSAQTVSGTATQTDDAAPTDGQPQTQPSENTENKSQPKRLHVSNIPFRFRDPDLRQMFGQF
GKILDVEIIFNERGSKGFGFVTFENSADADRAREKLHGTVVEGRKIEVNNATARVMTNKKTVNPYTNGWKLNPVVGAVYSPEFYAGTVLL
CQANQEGSSMYSAPSSLVYTSAMPGFPYPAATAAAAYRGAHLRGRGRTVYNTFRAAAPPPPIPAYGGVVYQDGFYGADIYGGYAAYRYAQ
PTPATAAAYSDRNQFVFVAADEISCNTSAVTDEFMLPTPTTTHLLQPPPTALVPCPKVPAPAQTSEELSCTLPGLCCQAAENLTASPPLL

--------------------------------------------------------------
>66648_66648_14_PMM2-RBFOX1_PMM2_chr16_8906963_ENST00000539622_RBFOX1_chr16_7568149_ENST00000550418_length(transcript)=1865nt_BP=603nt
GTGCCAACGTGTCTTGTAAGGTGCGGCTAGAAACTGGGGACATGGCAGCGCCTGGCCCAGCGCTCTGCCTCTTCGACGTGGATGGGACCC
TCACCGCCCCGCGGCAGAAAATTACCAAAGAAATGGATGACTTCCTACAAAAATTGAGGCAGAAGATCAAAATCGGAGTGGTAGGCGGAT
CGGACTTTGAGAAAGTGCAGGAGCAACTGGGAAATGATGAATATTCAAAGTCATCTGGGTGAGGCCCTAATCCAAGATTTAATCAACTAC
TGTCTGAGCTACATTGCGAAAATTAAACTCCCGAAGAAGAGGGGTACTTTCATTGAATTCCGAAATGGGATGTTAAACGTGTCCCCTATT
GGAAGAAGCTGCAGCCAAGAAGAACGCATTGAGTTCTACGAACTCGATAAAAAAGAAAATATAAGACAAAAGTTTGTAGCAGATCTACGG
AAAGAGTTTGCTGGAAAAGGCCTCACGTTTTCCATAGGAGGCCAGATCAGCTTTGATGTCTTTCCTGATGGATGGGACAAGAGATACTGT
CTGCGACATGTGGAAAATGACGGTTATAAGACCATTTATTTCTTTGGAGACAAAACTATGCCAGGTAATCAGGAAGCAGCCGCTGCCCCT
GACACAATGGCTCAGCCTTACGCTTCGGCCCAGTTTGCTCCCCCGCAGAACGGTATCCCCGCGGAATACACGGCCCCTCATCCCCACCCC
GCGCCAGAGTACACAGGCCAGACCACGGTTCCCGAGCACACATTAAACCTGTACCCTCCCGCCCAGACGCACTCCGAGCAGAGCCCGGCG
GACACGAGCGCTCAGACCGTCTCTGGCACCGCCACACAGACAGATGACGCAGCACCGACGGATGGCCAGCCCCAGACACAACCTTCTGAA
AACACGGAAAACAAGTCTCAGCCCAAGCGGCTGCATGTCTCCAATATCCCCTTCAGGTTCCGGGATCCGGACCTCAGACAAATGTTTGGT
CAATTTGGTAAAATCTTAGATGTTGAAATTATTTTTAATGAGCGAGGCTCAAAGGGATTTGGTTTCGTAACTTTCGAAAATAGTGCCGAT
GCGGACAGGGCGAGGGAGAAATTACACGGCACCGTGGTAGAGGGCCGTAAAATCGAGGTAAATAATGCCACAGCACGTGTAATGACAAAT
AAAAAGACCGTCAACCCTTATACAAATGGCTGGAAATTGAATCCAGTTGTGGGTGCAGTCTACAGTCCCGAATTCTATGCAGGCACGGTC
CTGTTGTGCCAGGCCAACCAGGAGGGATCTTCCATGTACAGTGCCCCCAGTTCACTTGTATATACTTCTGCAATGCCAGGCTTCCCGTAT
CCAGCAGCCACCGCCGCGGCCGCCTACCGAGGGGCGCACCTGCGAGGCCGCGGTCGCACCGTGTACAACACCTTCAGGGCCGCGGCGCCC
CCGCCCCCGATCCCGGCCTACGGCGGTGTTGTTTACCAGGATGGATTTTATGGTGCAGACATTTATGGTGGTTATGCTGCATACCGCTAC
GCCCAGCCTACCCCTGCCACTGCCGCTGCCTACAGTGACAGTTACGGACGAGTTTATGCTGCCGACCCCTACCACCACGCACTTGCTCCA
GCCCCCACCTACGGCGTTGGTGCCATGAATGCTTTTGCACCTTTGACTGATGCCAAGACTAGGAGCCATGCTGATGATGTGGGTCTCGTT
CTTTCTTCATTGCAGGCTAGTATATACCGAGGGGGATACAACCGTTTTGCTCCATACTAAATGACAAAACCATAAAAACCTTCCAATGTG

>66648_66648_14_PMM2-RBFOX1_PMM2_chr16_8906963_ENST00000539622_RBFOX1_chr16_7568149_ENST00000550418_length(amino acids)=527AA_BP=139
MRKCRSNWEMMNIQSHLGEALIQDLINYCLSYIAKIKLPKKRGTFIEFRNGMLNVSPIGRSCSQEERIEFYELDKKENIRQKFVADLRKE
FAGKGLTFSIGGQISFDVFPDGWDKRYCLRHVENDGYKTIYFFGDKTMPGNQEAAAAPDTMAQPYASAQFAPPQNGIPAEYTAPHPHPAP
EYTGQTTVPEHTLNLYPPAQTHSEQSPADTSAQTVSGTATQTDDAAPTDGQPQTQPSENTENKSQPKRLHVSNIPFRFRDPDLRQMFGQF
GKILDVEIIFNERGSKGFGFVTFENSADADRAREKLHGTVVEGRKIEVNNATARVMTNKKTVNPYTNGWKLNPVVGAVYSPEFYAGTVLL
CQANQEGSSMYSAPSSLVYTSAMPGFPYPAATAAAAYRGAHLRGRGRTVYNTFRAAAPPPPIPAYGGVVYQDGFYGADIYGGYAAYRYAQ

--------------------------------------------------------------
>66648_66648_15_PMM2-RBFOX1_PMM2_chr16_8906963_ENST00000539622_RBFOX1_chr16_7568149_ENST00000553186_length(transcript)=1784nt_BP=603nt
GTGCCAACGTGTCTTGTAAGGTGCGGCTAGAAACTGGGGACATGGCAGCGCCTGGCCCAGCGCTCTGCCTCTTCGACGTGGATGGGACCC
TCACCGCCCCGCGGCAGAAAATTACCAAAGAAATGGATGACTTCCTACAAAAATTGAGGCAGAAGATCAAAATCGGAGTGGTAGGCGGAT
CGGACTTTGAGAAAGTGCAGGAGCAACTGGGAAATGATGAATATTCAAAGTCATCTGGGTGAGGCCCTAATCCAAGATTTAATCAACTAC
TGTCTGAGCTACATTGCGAAAATTAAACTCCCGAAGAAGAGGGGTACTTTCATTGAATTCCGAAATGGGATGTTAAACGTGTCCCCTATT
GGAAGAAGCTGCAGCCAAGAAGAACGCATTGAGTTCTACGAACTCGATAAAAAAGAAAATATAAGACAAAAGTTTGTAGCAGATCTACGG
AAAGAGTTTGCTGGAAAAGGCCTCACGTTTTCCATAGGAGGCCAGATCAGCTTTGATGTCTTTCCTGATGGATGGGACAAGAGATACTGT
CTGCGACATGTGGAAAATGACGGTTATAAGACCATTTATTTCTTTGGAGACAAAACTATGCCAGGTAATCAGGAAGCAGCCGCTGCCCCT
GACACAATGGCTCAGCCTTACGCTTCGGCCCAGTTTGCTCCCCCGCAGAACGGTATCCCCGCGGAATACACGGCCCCTCATCCCCACCCC
GCGCCAGAGTACACAGGCCAGACCACGGTTCCCGAGCACACATTAAACCTGTACCCTCCCGCCCAGACGCACTCCGAGCAGAGCCCGGCG
GACACGAGCGCTCAGACCGTCTCTGGCACCGCCACACAGACAGATGACGCAGCACCGACGGATGGCCAGCCCCAGACACAACCTTCTGAA
AACACGGAAAACAAGTCTCAGCCCAAGCGGCTGCATGTCTCCAATATCCCCTTCAGGTTCCGGGATCCGGACCTCAGACAAATGTTTGGT
CAATTTGGTAAAATCTTAGATGTTGAAATTATTTTTAATGAGCGAGGCTCAAAGGGATTTGGTTTCGTAACTTTCGAAAATAGTGCCGAT
GCGGACAGGGCGAGGGAGAAATTACACGGCACCGTGGTAGAGGGCCGTAAAATCGAGGTAAATAATGCCACAGCACGTGTAATGACAAAT
AAAAAGACCGTCAACCCTTATACAAATGGCTGGAAATTGAATCCAGTTGTGGGTGCAGTCTACAGTCCCGAATTCTATGCAGTGCCAGGC
TTCCCGTATCCAGCAGCCACCGCCGCGGCCGCCTACCGAGGGGCGCACCTGCGAGGCCGCGGTCGCACCGTGTACAACACCTTCAGGGCC
GCGGCGCCCCCGCCCCCGATCCCGGCCTACGGCGGTGTTGTTTACCAGGATGGATTTTATGGTGCAGACATTTATGGTGGTTATGCTGCA
TACCGCTACGCCCAGCCTACCCCTGCCACTGCCGCTGCCTACAGTGACAGTTACGGACGAGTTTATGCTGCCGACCCCTACCACCACGCA
CTTGCTCCAGCCCCCACCTACGGCGTTGGTGCCATGAATGCTTTTGCACCTTTGACTGATGCCAAGACTAGGAGCCATGCTGATGATGTG
GGTCTCGTTCTTTCTTCATTGCAGGCTAGTATATACCGAGGGGGATACAACCGTTTTGCTCCATACTAAATGACAAAACCATAAAAACCT

>66648_66648_15_PMM2-RBFOX1_PMM2_chr16_8906963_ENST00000539622_RBFOX1_chr16_7568149_ENST00000553186_length(amino acids)=500AA_BP=139
MRKCRSNWEMMNIQSHLGEALIQDLINYCLSYIAKIKLPKKRGTFIEFRNGMLNVSPIGRSCSQEERIEFYELDKKENIRQKFVADLRKE
FAGKGLTFSIGGQISFDVFPDGWDKRYCLRHVENDGYKTIYFFGDKTMPGNQEAAAAPDTMAQPYASAQFAPPQNGIPAEYTAPHPHPAP
EYTGQTTVPEHTLNLYPPAQTHSEQSPADTSAQTVSGTATQTDDAAPTDGQPQTQPSENTENKSQPKRLHVSNIPFRFRDPDLRQMFGQF
GKILDVEIIFNERGSKGFGFVTFENSADADRAREKLHGTVVEGRKIEVNNATARVMTNKKTVNPYTNGWKLNPVVGAVYSPEFYAVPGFP
YPAATAAAAYRGAHLRGRGRTVYNTFRAAAPPPPIPAYGGVVYQDGFYGADIYGGYAAYRYAQPTPATAAAYSDSYGRVYAADPYHHALA

--------------------------------------------------------------
>66648_66648_16_PMM2-RBFOX1_PMM2_chr16_8906963_ENST00000566983_RBFOX1_chr16_7568149_ENST00000422070_length(transcript)=2094nt_BP=762nt
GAACTCACGAGTCTTGCAGTCATAAAGCAGCAACATAAAGCAAGCTCCCAACTCTAGTTCTCCAGGCAATTCATCCAGGCTGTCCCCTGC
AAGCTGCTCAGCCCACCAGATCTGCTTTGGGGAGCGCATTAAACATGGTTATGCAATGATTGGGTGGCGGATGCCATAGACATCTGGCCC
TATGACAAGAAAATTACCAAAGAAATGGATGACTTCCTACAAAAATTGAGGCAGAAGATCAAAATCGGAGTGGTAGGCGGATCGGACTTT
GAGAAAGTGCAGGAGCAACTGGGAAATGATGTGGTTGAAAAATACGATTATGTGTTTCCAGAAAATGGCTTGGTAGCATACAAAGATGGG
AAACTCTTGTGTAGACAGAATATTCAAAGTCATCTGGGTGAGGCCCTAATCCAAGATTTAATCAACTACTGTCTGAGCTACATTGCGAAA
ATTAAACTCCCGAAGAAGAGGGGTACTTTCATTGAATTCCGAAATGGGATGTTAAACGTGTCCCCTATTGGAAGAAGCTGCAGCCAAGAA
GAACGCATTGAGTTCTACGAACTCGATAAAAAAGAAAATATAAGACAAAAGTTTGTAGCAGATCTACGGAAAGAGTTTGCTGGAAAAGGC
CTCACGTTTTCCATAGGAGGCCAGATCAGCTTTGATGTCTTTCCTGATGGATGGGACAAGAGATACTGTCTGCGACATGTGGAAAATGAC
GGTTATAAGACCATTTATTTCTTTGGAGACAAAACTATGCCAGGTAATCAGGAAGCAGCCGCTGCCCCTGACACAATGGCTCAGCCTTAC
GCTTCGGCCCAGTTTGCTCCCCCGCAGAACGGTATCCCCGCGGAATACACGGCCCCTCATCCCCACCCCGCGCCAGAGTACACAGGCCAG
ACCACGGTTCCCGAGCACACATTAAACCTGTACCCTCCCGCCCAGACGCACTCCGAGCAGAGCCCGGCGGACACGAGCGCTCAGACCGTC
TCTGGCACCGCCACACAGACAGATGACGCAGCACCGACGGATGGCCAGCCCCAGACACAACCTTCTGAAAACACGGAAAACAAGTCTCAG
CCCAAGCGGCTGCATGTCTCCAATATCCCCTTCAGGTTCCGGGATCCGGACCTCAGACAAATGTTTGGTCAATTTGGTAAAATCTTAGAT
GTTGAAATTATTTTTAATGAGCGAGGCTCAAAGGGATTTGGTTTCGTAACTTTCGAAAATAGTGCCGATGCGGACAGGGCGAGGGAGAAA
TTACACGGCACCGTGGTAGAGGGCCGTAAAATCGAGGTAAATAATGCCACAGCACGTGTAATGACAAATAAAAAGACCGTCAACCCTTAT
ACAAATGGCTGGAAATTGAATCCAGTTGTGGGTGCAGTCTACAGTCCCGAATTCTATGCAGGCACGGTCCTGTTGTGCCAGGCCAACCAG
GAGGGATCTTCCATGTACAGTGCCCCCAGTTCACTTGTATATACTTCTGCAATGCCAGGCTTCCCGTATCCAGCAGCCACCGCCGCGGCC
GCCTACCGAGGGGCGCACCTGCGAGGCCGCGGTCGCACCGTGTACAACACCTTCAGGGCCGCGGCGCCCCCGCCCCCGATCCCGGCCTAC
GGCGGTGTTGTTTACCAGGATGGATTTTATGGTGCAGACATTTATGGTGGTTATGCTGCATACCGCTACGCCCAGCCTACCCCTGCCACT
GCCGCTGCCTACAGTGACAGTTACGGACGAGTTTATGCTGCCGACCCCTACCACCACGCACTTGCTCCAGCCCCCACCTACGGCGTTGGT
GCCATGCCCCAAGGTTCCAGCCCCAGCACAGACTTCAGAGGAGCTAAGCTGCACACTTCCAGGCCTCTGCTGTCAGGCAGCTGAGAATCT
GACTGCCTCTCCTCCCCTATTACAATTCATGTTTAAAGTCATAGTCGCCCAGGAAAGAAAATAGAGAGGGGCACACTTTGTGTGTGTACC
TAGTACATAAGAAAGTAGAAGGAATCAGCTGGGTTTGGGGGTTGCCTTTTGTTTTGGGGCAGGTCTGGGTTTTTGTTTTGGGAGGGGGTG

>66648_66648_16_PMM2-RBFOX1_PMM2_chr16_8906963_ENST00000566983_RBFOX1_chr16_7568149_ENST00000422070_length(amino acids)=559AA_BP=186
MDDFLQKLRQKIKIGVVGGSDFEKVQEQLGNDVVEKYDYVFPENGLVAYKDGKLLCRQNIQSHLGEALIQDLINYCLSYIAKIKLPKKRG
TFIEFRNGMLNVSPIGRSCSQEERIEFYELDKKENIRQKFVADLRKEFAGKGLTFSIGGQISFDVFPDGWDKRYCLRHVENDGYKTIYFF
GDKTMPGNQEAAAAPDTMAQPYASAQFAPPQNGIPAEYTAPHPHPAPEYTGQTTVPEHTLNLYPPAQTHSEQSPADTSAQTVSGTATQTD
DAAPTDGQPQTQPSENTENKSQPKRLHVSNIPFRFRDPDLRQMFGQFGKILDVEIIFNERGSKGFGFVTFENSADADRAREKLHGTVVEG
RKIEVNNATARVMTNKKTVNPYTNGWKLNPVVGAVYSPEFYAGTVLLCQANQEGSSMYSAPSSLVYTSAMPGFPYPAATAAAAYRGAHLR
GRGRTVYNTFRAAAPPPPIPAYGGVVYQDGFYGADIYGGYAAYRYAQPTPATAAAYSDSYGRVYAADPYHHALAPAPTYGVGAMPQGSSP

--------------------------------------------------------------
>66648_66648_17_PMM2-RBFOX1_PMM2_chr16_8906963_ENST00000566983_RBFOX1_chr16_7568149_ENST00000535565_length(transcript)=1905nt_BP=762nt
GAACTCACGAGTCTTGCAGTCATAAAGCAGCAACATAAAGCAAGCTCCCAACTCTAGTTCTCCAGGCAATTCATCCAGGCTGTCCCCTGC
AAGCTGCTCAGCCCACCAGATCTGCTTTGGGGAGCGCATTAAACATGGTTATGCAATGATTGGGTGGCGGATGCCATAGACATCTGGCCC
TATGACAAGAAAATTACCAAAGAAATGGATGACTTCCTACAAAAATTGAGGCAGAAGATCAAAATCGGAGTGGTAGGCGGATCGGACTTT
GAGAAAGTGCAGGAGCAACTGGGAAATGATGTGGTTGAAAAATACGATTATGTGTTTCCAGAAAATGGCTTGGTAGCATACAAAGATGGG
AAACTCTTGTGTAGACAGAATATTCAAAGTCATCTGGGTGAGGCCCTAATCCAAGATTTAATCAACTACTGTCTGAGCTACATTGCGAAA
ATTAAACTCCCGAAGAAGAGGGGTACTTTCATTGAATTCCGAAATGGGATGTTAAACGTGTCCCCTATTGGAAGAAGCTGCAGCCAAGAA
GAACGCATTGAGTTCTACGAACTCGATAAAAAAGAAAATATAAGACAAAAGTTTGTAGCAGATCTACGGAAAGAGTTTGCTGGAAAAGGC
CTCACGTTTTCCATAGGAGGCCAGATCAGCTTTGATGTCTTTCCTGATGGATGGGACAAGAGATACTGTCTGCGACATGTGGAAAATGAC
GGTTATAAGACCATTTATTTCTTTGGAGACAAAACTATGCCAGGTAATCAGGAAGCAGCCGCTGCCCCTGACACAATGGCTCAGCCTTAC
GCTTCGGCCCAGTTTGCTCCCCCGCAGAACGGTATCCCCGCGGAATACACGGCCCCTCATCCCCACCCCGCGCCAGAGTACACAGGCCAG
ACCACGGTTCCCGAGCACACATTAAACCTGTACCCTCCCGCCCAGACGCACTCCGAGCAGAGCCCGGCGGACACGAGCGCTCAGACCGTC
TCTGGCACCGCCACACAATTTGGTAAAATCTTAGATGTTGAAATTATTTTTAATGAGCGAGGCTCAAAGGTAAATAATGCCACAGCACGT
GTAATGACAAATAAAAAGACCGTCAACCCTTATACAAATGGCTGGAAATTGAATCCAGTTGTGGGTGCAGTCTACAGTCCCGAATTCTAT
GCAGGCACGGTCCTGTTGTGCCAGGCCAACCAGGAGGGATCTTCCATGTACAGTGCCCCCAGTTCACTTGTATATACTTCTGCAATGCCA
GGCTTCCCGTATCCAGCAGCCACCGCCGCGGCCGCCTACCGAGGGGCGCACCTGCGAGGCCGCGGTCGCACCGTGTACAACACCTTCAGG
GCCGCGGCGCCCCCGCCCCCGATCCCGGCCTACGGCGGTGTTGTTTACCAGGATGGATTTTATGGTGCAGACATTTATGGTGGTTATGCT
GCATACCGCTACGCCCAGCCTACCCCTGCCACTGCCGCTGCCTACAGTGACAGAAATCAGTTCGTCTTCGTTGCAGCAGATGAAATTTCT
TGTAACACCTCTGCAGTTACGGACGAGTTTATGCTGCCGACCCCTACCACCACGCACTTGCTCCAGCCCCCACCTACGGCGTTGGTGCCA
TGCCCCAAGGTTCCAGCCCCAGCACAGACTTCAGAGGAGCTAAGCTGCACACTTCCAGGCCTCTGCTGTCAGGCAGCTGAGAATCTGACT
GCCTCTCCTCCCCTATTACAATTCATGTTTAAAGTCATAGTCGCCCAGGAAAGAAAATAGAGAGGGGCACACTTTGTGTGTGTACCTAGT
ACATAAGAAAGTAGAAGGAATCAGCTGGGTTTGGGGGTTGCCTTTTGTTTTGGGGCAGGTCTGGGTTTTTGTTTTGGGAGGGGGTGGGGG

>66648_66648_17_PMM2-RBFOX1_PMM2_chr16_8906963_ENST00000566983_RBFOX1_chr16_7568149_ENST00000535565_length(amino acids)=521AA_BP=186
MDDFLQKLRQKIKIGVVGGSDFEKVQEQLGNDVVEKYDYVFPENGLVAYKDGKLLCRQNIQSHLGEALIQDLINYCLSYIAKIKLPKKRG
TFIEFRNGMLNVSPIGRSCSQEERIEFYELDKKENIRQKFVADLRKEFAGKGLTFSIGGQISFDVFPDGWDKRYCLRHVENDGYKTIYFF
GDKTMPGNQEAAAAPDTMAQPYASAQFAPPQNGIPAEYTAPHPHPAPEYTGQTTVPEHTLNLYPPAQTHSEQSPADTSAQTVSGTATQFG
KILDVEIIFNERGSKVNNATARVMTNKKTVNPYTNGWKLNPVVGAVYSPEFYAGTVLLCQANQEGSSMYSAPSSLVYTSAMPGFPYPAAT
AAAAYRGAHLRGRGRTVYNTFRAAAPPPPIPAYGGVVYQDGFYGADIYGGYAAYRYAQPTPATAAAYSDRNQFVFVAADEISCNTSAVTD

--------------------------------------------------------------
>66648_66648_18_PMM2-RBFOX1_PMM2_chr16_8906963_ENST00000566983_RBFOX1_chr16_7568149_ENST00000547372_length(transcript)=3824nt_BP=762nt
GAACTCACGAGTCTTGCAGTCATAAAGCAGCAACATAAAGCAAGCTCCCAACTCTAGTTCTCCAGGCAATTCATCCAGGCTGTCCCCTGC
AAGCTGCTCAGCCCACCAGATCTGCTTTGGGGAGCGCATTAAACATGGTTATGCAATGATTGGGTGGCGGATGCCATAGACATCTGGCCC
TATGACAAGAAAATTACCAAAGAAATGGATGACTTCCTACAAAAATTGAGGCAGAAGATCAAAATCGGAGTGGTAGGCGGATCGGACTTT
GAGAAAGTGCAGGAGCAACTGGGAAATGATGTGGTTGAAAAATACGATTATGTGTTTCCAGAAAATGGCTTGGTAGCATACAAAGATGGG
AAACTCTTGTGTAGACAGAATATTCAAAGTCATCTGGGTGAGGCCCTAATCCAAGATTTAATCAACTACTGTCTGAGCTACATTGCGAAA
ATTAAACTCCCGAAGAAGAGGGGTACTTTCATTGAATTCCGAAATGGGATGTTAAACGTGTCCCCTATTGGAAGAAGCTGCAGCCAAGAA
GAACGCATTGAGTTCTACGAACTCGATAAAAAAGAAAATATAAGACAAAAGTTTGTAGCAGATCTACGGAAAGAGTTTGCTGGAAAAGGC
CTCACGTTTTCCATAGGAGGCCAGATCAGCTTTGATGTCTTTCCTGATGGATGGGACAAGAGATACTGTCTGCGACATGTGGAAAATGAC
GGTTATAAGACCATTTATTTCTTTGGAGACAAAACTATGCCAGGTAATCAGGAAGCAGCCGCTGCCCCTGACACAATGGCTCAGCCTTAC
GCTTCGGCCCAGTTTGCTCCCCCGCAGAACGGTATCCCCGCGGAATACACGGCCCCTCATCCCCACCCCGCGCCAGAGTACACAGGCCAG
ACCACGGTTCCCGAGCACACATTAAACCTGTACCCTCCCGCCCAGACGCACTCCGAGCAGAGCCCGGCGGACACGAGCGCTCAGACCGTC
TCTGGCACCGCCACACAGACAGATGACGCAGCACCGACGGATGGCCAGCCCCAGACACAACCTTCTGAAAACACGGAAAACAAGTCTCAG
CCCAAGCGGCTGCATGTCTCCAATATCCCCTTCAGGTTCCGGGATCCGGACCTCAGACAAATGTTTGGTCAATTTGGTAAAATCTTAGAT
GTTGAAATTATTTTTAATGAGCGAGGCTCAAAGGGATTTGGTTTCGTAACTTTCGAAAATAGTGCCGATGCGGACAGGGCGAGGGAGAAA
TTACACGGCACCGTGGTAGAGGGCCGTAAAATCGAGGTAAATAATGCCACAGCACGTGTAATGACAAATAAAAAGACCGTCAACCCTTAT
ACAAATGGCTGGAAATTGAATCCAGTTGTGGGTGCAGTCTACAGTCCCGAATTCTATGCAGGCACGGTCCTGTTGTGCCAGGCCAACCAG
GAGGGATCTTCCATGTACAGTGCCCCCAGTTCACTTGTATATACTTCTGCAATGCCAGGCTTCCCGTATCCAGCAGCCACCGCCGCGGCC
GCCTACCGAGGGGCGCACCTGCGAGGCCGCGGTCGCACCGTGTACAACACCTTCAGGGCCGCGGCGCCCCCGCCCCCGATCCCGGCCTAC
GGCGGTGTTGTTTACCAGGATGGATTTTATGGTGCAGACATTTATGGTGGTTATGCTGCATACCGCTACGCCCAGCCTACCCCTGCCACT
GCCGCTGCCTACAGTGACAGAAATCAGTTCGTCTTCGTTGCAGCAGATGAAATTTCTTGTAACACCTCTGCAGTTACGGACGAGTTTATG
CTGCCGACCCCTACCACCACGCACTTGCTCCAGCCCCCACCTACGGCGTTGGTGCCATGCCCCAAGGTTCCAGCCCCAGCACAGACTTCA
GAGGAGCTAAGCTGCACACTTCCAGGCCTCTGCTGTCAGGCAGCTGAGAATCTGACTGCCTCTCCTCCCCTATTACAATTCATGTTTAAA
GTCATAGTCGCCCAGGAAAGAAAATAGAGAGGGGCACACTTTGTGTGTGTACCTAGTACATAAGAAAGTAGAAGGAATCAGCTGGGTTTG
GGGGTTGCCTTTTGTTTTGGGGCAGGTCTGGGTTTTTGTTTTGGGAGGGGGTGGGGGGAGGGTAAAAAATGGGAGGTAAGGGTGGGGTGA
ACTTGCCTGTACTTGTTCAAACTTCTATGCACTGAAACTCTTGAGTACAGTAAGACGTGCCCATCACGTGAGAGCATATGCAATCATTAC
AAAGCTTTGGCATGCAGTTTTCTGCTTGGATCAAGAATATCAGTCCTTACCCTAAAAATGAATCCCCATAGGCATTCATTTGAATTGCCA
ATACTTTTAGAAAAAGGAAATCGTTAAGTGCCACCTTGTAGCCATTAAAACCATGGCCGGACAGTTCACTGAAGCTCAGTCATAGAAATT
CAGCCATGATTTGGAAGCATTGTTTTGCACAAGCTTAATTACATCAAGCAATTCATCTGTACAACTCCACAACTCCCTTCTCAAGATCAG
ATTCCATACAGCTTACAGAGCCAAGTTAAGTAAGAAGTAGGTTGAGATTTTCATCCCAATTCTGCATTCAACAACTCTGCTTCAACACCT
AGTCCACATGAGGAATGTGTTGGAGAGTTGAATTACATTCAACAACTGGTCCAAATTCAACCTCAAGTGCAGATTATTCTGTTATAAAAA
AATGAGACAGTGAAAATCCTTCCATTGTCCAGCTTATAATAGAGTCCTTTTAGCTAAGAGGACTGGCTGACAGAATTTGGTTTTGCAGGG
AATTTCTTTAGGAGGAGCTATTGGGGAAGGTCAGGAATGGCCCTATCTTTAGTTCTCCAAGAATGACCTGGGATGGGTAGGGGGTGCCTC
CATTTCGGTTGGTTTTGAGTGTCTATTTTTCACATTAGTCTTTTTGATGATCCACATGTTGCAAAAGGAAAATGTAAAAAACACACCCCT
CAAATTGCTTTGTTTCAGAATGCTTTTGCACCTTTGACTGATGCCAAGACTAGGAGCCATGCTGATGATGTGGGTCTCGTTCTTTCTTCA
TTGCAGGCTAGTATATACCGAGGGGGATACAACCGTTTTGCTCCATACTAAATGACAAAACCATAAAAACCTTCCAATGTGGGGAGAAAG
GAAGCTTTCCGAGGCCTGAGTATTGCAATACATGCAGTAGTACATCATTTTAGCAACTCTAAAAAAAAAAAAAATACAAATAAAAAGGAA
AAAAAATTACATTTTTTATCTTATACCTCAGATATTTTGTTCTGTGTATTTTAATATTGTGGGTCTTTAATTTCTGAAGGTTCCGTAGTT
TGGTTGCTGGCTGTAGGAGTTTTTGTGGTTGATCTAGACAGATGCTAGATAATGAATAAAAACTGGTTTAGGGCCATATCCAGAGTGCTA
TATTATGTAAATGAATTATATATGCTGAATATTAAGCTACTGGGGTTATCAGCTATTTGGGAAGAGTGTAAGTGACTACAGTAGTCATTT
TTTTCTGCACCTGCATTATTTTATTTTGCGAAAGGGGAGGTTGGGAGGGGCTTAGGGGATTGGAACTGGGGTTTGGCTGAAAGAAAAAAA
AAAAAATGTAACTGATGAATCTAAACGACCCACTGCACCAACAATCATTTATCAATGGTTCTAAGTTACTCATTGCCAGTTCAAGCCAAA
GGTCATGTTGTTAAGGGGGTGCTTCTAGTAGCACTTGTGCATCTGAGTTGAATGAAGCTGTGCAAACCCACCCTTTAAACCATTCCACCC

>66648_66648_18_PMM2-RBFOX1_PMM2_chr16_8906963_ENST00000566983_RBFOX1_chr16_7568149_ENST00000547372_length(amino acids)=600AA_BP=186
MDDFLQKLRQKIKIGVVGGSDFEKVQEQLGNDVVEKYDYVFPENGLVAYKDGKLLCRQNIQSHLGEALIQDLINYCLSYIAKIKLPKKRG
TFIEFRNGMLNVSPIGRSCSQEERIEFYELDKKENIRQKFVADLRKEFAGKGLTFSIGGQISFDVFPDGWDKRYCLRHVENDGYKTIYFF
GDKTMPGNQEAAAAPDTMAQPYASAQFAPPQNGIPAEYTAPHPHPAPEYTGQTTVPEHTLNLYPPAQTHSEQSPADTSAQTVSGTATQTD
DAAPTDGQPQTQPSENTENKSQPKRLHVSNIPFRFRDPDLRQMFGQFGKILDVEIIFNERGSKGFGFVTFENSADADRAREKLHGTVVEG
RKIEVNNATARVMTNKKTVNPYTNGWKLNPVVGAVYSPEFYAGTVLLCQANQEGSSMYSAPSSLVYTSAMPGFPYPAATAAAAYRGAHLR
GRGRTVYNTFRAAAPPPPIPAYGGVVYQDGFYGADIYGGYAAYRYAQPTPATAAAYSDRNQFVFVAADEISCNTSAVTDEFMLPTPTTTH

--------------------------------------------------------------
>66648_66648_19_PMM2-RBFOX1_PMM2_chr16_8906963_ENST00000566983_RBFOX1_chr16_7568149_ENST00000550418_length(transcript)=2024nt_BP=762nt
GAACTCACGAGTCTTGCAGTCATAAAGCAGCAACATAAAGCAAGCTCCCAACTCTAGTTCTCCAGGCAATTCATCCAGGCTGTCCCCTGC
AAGCTGCTCAGCCCACCAGATCTGCTTTGGGGAGCGCATTAAACATGGTTATGCAATGATTGGGTGGCGGATGCCATAGACATCTGGCCC
TATGACAAGAAAATTACCAAAGAAATGGATGACTTCCTACAAAAATTGAGGCAGAAGATCAAAATCGGAGTGGTAGGCGGATCGGACTTT
GAGAAAGTGCAGGAGCAACTGGGAAATGATGTGGTTGAAAAATACGATTATGTGTTTCCAGAAAATGGCTTGGTAGCATACAAAGATGGG
AAACTCTTGTGTAGACAGAATATTCAAAGTCATCTGGGTGAGGCCCTAATCCAAGATTTAATCAACTACTGTCTGAGCTACATTGCGAAA
ATTAAACTCCCGAAGAAGAGGGGTACTTTCATTGAATTCCGAAATGGGATGTTAAACGTGTCCCCTATTGGAAGAAGCTGCAGCCAAGAA
GAACGCATTGAGTTCTACGAACTCGATAAAAAAGAAAATATAAGACAAAAGTTTGTAGCAGATCTACGGAAAGAGTTTGCTGGAAAAGGC
CTCACGTTTTCCATAGGAGGCCAGATCAGCTTTGATGTCTTTCCTGATGGATGGGACAAGAGATACTGTCTGCGACATGTGGAAAATGAC
GGTTATAAGACCATTTATTTCTTTGGAGACAAAACTATGCCAGGTAATCAGGAAGCAGCCGCTGCCCCTGACACAATGGCTCAGCCTTAC
GCTTCGGCCCAGTTTGCTCCCCCGCAGAACGGTATCCCCGCGGAATACACGGCCCCTCATCCCCACCCCGCGCCAGAGTACACAGGCCAG
ACCACGGTTCCCGAGCACACATTAAACCTGTACCCTCCCGCCCAGACGCACTCCGAGCAGAGCCCGGCGGACACGAGCGCTCAGACCGTC
TCTGGCACCGCCACACAGACAGATGACGCAGCACCGACGGATGGCCAGCCCCAGACACAACCTTCTGAAAACACGGAAAACAAGTCTCAG
CCCAAGCGGCTGCATGTCTCCAATATCCCCTTCAGGTTCCGGGATCCGGACCTCAGACAAATGTTTGGTCAATTTGGTAAAATCTTAGAT
GTTGAAATTATTTTTAATGAGCGAGGCTCAAAGGGATTTGGTTTCGTAACTTTCGAAAATAGTGCCGATGCGGACAGGGCGAGGGAGAAA
TTACACGGCACCGTGGTAGAGGGCCGTAAAATCGAGGTAAATAATGCCACAGCACGTGTAATGACAAATAAAAAGACCGTCAACCCTTAT
ACAAATGGCTGGAAATTGAATCCAGTTGTGGGTGCAGTCTACAGTCCCGAATTCTATGCAGGCACGGTCCTGTTGTGCCAGGCCAACCAG
GAGGGATCTTCCATGTACAGTGCCCCCAGTTCACTTGTATATACTTCTGCAATGCCAGGCTTCCCGTATCCAGCAGCCACCGCCGCGGCC
GCCTACCGAGGGGCGCACCTGCGAGGCCGCGGTCGCACCGTGTACAACACCTTCAGGGCCGCGGCGCCCCCGCCCCCGATCCCGGCCTAC
GGCGGTGTTGTTTACCAGGATGGATTTTATGGTGCAGACATTTATGGTGGTTATGCTGCATACCGCTACGCCCAGCCTACCCCTGCCACT
GCCGCTGCCTACAGTGACAGTTACGGACGAGTTTATGCTGCCGACCCCTACCACCACGCACTTGCTCCAGCCCCCACCTACGGCGTTGGT
GCCATGAATGCTTTTGCACCTTTGACTGATGCCAAGACTAGGAGCCATGCTGATGATGTGGGTCTCGTTCTTTCTTCATTGCAGGCTAGT
ATATACCGAGGGGGATACAACCGTTTTGCTCCATACTAAATGACAAAACCATAAAAACCTTCCAATGTGGGGAGAAAGGAAGCTTTCCGA

>66648_66648_19_PMM2-RBFOX1_PMM2_chr16_8906963_ENST00000566983_RBFOX1_chr16_7568149_ENST00000550418_length(amino acids)=574AA_BP=186
MDDFLQKLRQKIKIGVVGGSDFEKVQEQLGNDVVEKYDYVFPENGLVAYKDGKLLCRQNIQSHLGEALIQDLINYCLSYIAKIKLPKKRG
TFIEFRNGMLNVSPIGRSCSQEERIEFYELDKKENIRQKFVADLRKEFAGKGLTFSIGGQISFDVFPDGWDKRYCLRHVENDGYKTIYFF
GDKTMPGNQEAAAAPDTMAQPYASAQFAPPQNGIPAEYTAPHPHPAPEYTGQTTVPEHTLNLYPPAQTHSEQSPADTSAQTVSGTATQTD
DAAPTDGQPQTQPSENTENKSQPKRLHVSNIPFRFRDPDLRQMFGQFGKILDVEIIFNERGSKGFGFVTFENSADADRAREKLHGTVVEG
RKIEVNNATARVMTNKKTVNPYTNGWKLNPVVGAVYSPEFYAGTVLLCQANQEGSSMYSAPSSLVYTSAMPGFPYPAATAAAAYRGAHLR
GRGRTVYNTFRAAAPPPPIPAYGGVVYQDGFYGADIYGGYAAYRYAQPTPATAAAYSDSYGRVYAADPYHHALAPAPTYGVGAMNAFAPL

--------------------------------------------------------------
>66648_66648_20_PMM2-RBFOX1_PMM2_chr16_8906963_ENST00000566983_RBFOX1_chr16_7568149_ENST00000553186_length(transcript)=1943nt_BP=762nt
GAACTCACGAGTCTTGCAGTCATAAAGCAGCAACATAAAGCAAGCTCCCAACTCTAGTTCTCCAGGCAATTCATCCAGGCTGTCCCCTGC
AAGCTGCTCAGCCCACCAGATCTGCTTTGGGGAGCGCATTAAACATGGTTATGCAATGATTGGGTGGCGGATGCCATAGACATCTGGCCC
TATGACAAGAAAATTACCAAAGAAATGGATGACTTCCTACAAAAATTGAGGCAGAAGATCAAAATCGGAGTGGTAGGCGGATCGGACTTT
GAGAAAGTGCAGGAGCAACTGGGAAATGATGTGGTTGAAAAATACGATTATGTGTTTCCAGAAAATGGCTTGGTAGCATACAAAGATGGG
AAACTCTTGTGTAGACAGAATATTCAAAGTCATCTGGGTGAGGCCCTAATCCAAGATTTAATCAACTACTGTCTGAGCTACATTGCGAAA
ATTAAACTCCCGAAGAAGAGGGGTACTTTCATTGAATTCCGAAATGGGATGTTAAACGTGTCCCCTATTGGAAGAAGCTGCAGCCAAGAA
GAACGCATTGAGTTCTACGAACTCGATAAAAAAGAAAATATAAGACAAAAGTTTGTAGCAGATCTACGGAAAGAGTTTGCTGGAAAAGGC
CTCACGTTTTCCATAGGAGGCCAGATCAGCTTTGATGTCTTTCCTGATGGATGGGACAAGAGATACTGTCTGCGACATGTGGAAAATGAC
GGTTATAAGACCATTTATTTCTTTGGAGACAAAACTATGCCAGGTAATCAGGAAGCAGCCGCTGCCCCTGACACAATGGCTCAGCCTTAC
GCTTCGGCCCAGTTTGCTCCCCCGCAGAACGGTATCCCCGCGGAATACACGGCCCCTCATCCCCACCCCGCGCCAGAGTACACAGGCCAG
ACCACGGTTCCCGAGCACACATTAAACCTGTACCCTCCCGCCCAGACGCACTCCGAGCAGAGCCCGGCGGACACGAGCGCTCAGACCGTC
TCTGGCACCGCCACACAGACAGATGACGCAGCACCGACGGATGGCCAGCCCCAGACACAACCTTCTGAAAACACGGAAAACAAGTCTCAG
CCCAAGCGGCTGCATGTCTCCAATATCCCCTTCAGGTTCCGGGATCCGGACCTCAGACAAATGTTTGGTCAATTTGGTAAAATCTTAGAT
GTTGAAATTATTTTTAATGAGCGAGGCTCAAAGGGATTTGGTTTCGTAACTTTCGAAAATAGTGCCGATGCGGACAGGGCGAGGGAGAAA
TTACACGGCACCGTGGTAGAGGGCCGTAAAATCGAGGTAAATAATGCCACAGCACGTGTAATGACAAATAAAAAGACCGTCAACCCTTAT
ACAAATGGCTGGAAATTGAATCCAGTTGTGGGTGCAGTCTACAGTCCCGAATTCTATGCAGTGCCAGGCTTCCCGTATCCAGCAGCCACC
GCCGCGGCCGCCTACCGAGGGGCGCACCTGCGAGGCCGCGGTCGCACCGTGTACAACACCTTCAGGGCCGCGGCGCCCCCGCCCCCGATC
CCGGCCTACGGCGGTGTTGTTTACCAGGATGGATTTTATGGTGCAGACATTTATGGTGGTTATGCTGCATACCGCTACGCCCAGCCTACC
CCTGCCACTGCCGCTGCCTACAGTGACAGTTACGGACGAGTTTATGCTGCCGACCCCTACCACCACGCACTTGCTCCAGCCCCCACCTAC
GGCGTTGGTGCCATGAATGCTTTTGCACCTTTGACTGATGCCAAGACTAGGAGCCATGCTGATGATGTGGGTCTCGTTCTTTCTTCATTG
CAGGCTAGTATATACCGAGGGGGATACAACCGTTTTGCTCCATACTAAATGACAAAACCATAAAAACCTTCCAATGTGGGGAGAAAGGAA

>66648_66648_20_PMM2-RBFOX1_PMM2_chr16_8906963_ENST00000566983_RBFOX1_chr16_7568149_ENST00000553186_length(amino acids)=547AA_BP=186
MDDFLQKLRQKIKIGVVGGSDFEKVQEQLGNDVVEKYDYVFPENGLVAYKDGKLLCRQNIQSHLGEALIQDLINYCLSYIAKIKLPKKRG
TFIEFRNGMLNVSPIGRSCSQEERIEFYELDKKENIRQKFVADLRKEFAGKGLTFSIGGQISFDVFPDGWDKRYCLRHVENDGYKTIYFF
GDKTMPGNQEAAAAPDTMAQPYASAQFAPPQNGIPAEYTAPHPHPAPEYTGQTTVPEHTLNLYPPAQTHSEQSPADTSAQTVSGTATQTD
DAAPTDGQPQTQPSENTENKSQPKRLHVSNIPFRFRDPDLRQMFGQFGKILDVEIIFNERGSKGFGFVTFENSADADRAREKLHGTVVEG
RKIEVNNATARVMTNKKTVNPYTNGWKLNPVVGAVYSPEFYAVPGFPYPAATAAAAYRGAHLRGRGRTVYNTFRAAAPPPPIPAYGGVVY
QDGFYGADIYGGYAAYRYAQPTPATAAAYSDSYGRVYAADPYHHALAPAPTYGVGAMNAFAPLTDAKTRSHADDVGLVLSSLQASIYRGG

--------------------------------------------------------------
>66648_66648_21_PMM2-RBFOX1_PMM2_chr16_8906963_ENST00000569958_RBFOX1_chr16_7568149_ENST00000422070_length(transcript)=1714nt_BP=382nt
GCTAGAAACTGGGGACATGGCAGCGCCTGGCCCAGCGCTCTGCCTCTTCGACGTGGATGGGACCCTCACCGCCCCGCGGCAGAAAATTAC
CAAAGAAATGGATGACTTCCTACAAAAATTGAGGCAGAAGATCAAAATCGGAGTGGTAGGCGGATCGGACTTTGAGAAAGTGCAGGAGCA
ACTGGGAAATGATGAAAATATAAGACAAAAGTTTGTAGCAGATCTACGGAAAGAGTTTGCTGGAAAAGGCCTCACGTTTTCCATAGGAGG
CCAGATCAGCTTTGATGTCTTTCCTGATGGATGGGACAAGAGATACTGTCTGCGACATGTGGAAAATGACGGTTATAAGACCATTTATTT
CTTTGGAGACAAAACTATGCCAGGTAATCAGGAAGCAGCCGCTGCCCCTGACACAATGGCTCAGCCTTACGCTTCGGCCCAGTTTGCTCC
CCCGCAGAACGGTATCCCCGCGGAATACACGGCCCCTCATCCCCACCCCGCGCCAGAGTACACAGGCCAGACCACGGTTCCCGAGCACAC
ATTAAACCTGTACCCTCCCGCCCAGACGCACTCCGAGCAGAGCCCGGCGGACACGAGCGCTCAGACCGTCTCTGGCACCGCCACACAGAC
AGATGACGCAGCACCGACGGATGGCCAGCCCCAGACACAACCTTCTGAAAACACGGAAAACAAGTCTCAGCCCAAGCGGCTGCATGTCTC
CAATATCCCCTTCAGGTTCCGGGATCCGGACCTCAGACAAATGTTTGGTCAATTTGGTAAAATCTTAGATGTTGAAATTATTTTTAATGA
GCGAGGCTCAAAGGGATTTGGTTTCGTAACTTTCGAAAATAGTGCCGATGCGGACAGGGCGAGGGAGAAATTACACGGCACCGTGGTAGA
GGGCCGTAAAATCGAGGTAAATAATGCCACAGCACGTGTAATGACAAATAAAAAGACCGTCAACCCTTATACAAATGGCTGGAAATTGAA
TCCAGTTGTGGGTGCAGTCTACAGTCCCGAATTCTATGCAGGCACGGTCCTGTTGTGCCAGGCCAACCAGGAGGGATCTTCCATGTACAG
TGCCCCCAGTTCACTTGTATATACTTCTGCAATGCCAGGCTTCCCGTATCCAGCAGCCACCGCCGCGGCCGCCTACCGAGGGGCGCACCT
GCGAGGCCGCGGTCGCACCGTGTACAACACCTTCAGGGCCGCGGCGCCCCCGCCCCCGATCCCGGCCTACGGCGGTGTTGTTTACCAGGA
TGGATTTTATGGTGCAGACATTTATGGTGGTTATGCTGCATACCGCTACGCCCAGCCTACCCCTGCCACTGCCGCTGCCTACAGTGACAG
TTACGGACGAGTTTATGCTGCCGACCCCTACCACCACGCACTTGCTCCAGCCCCCACCTACGGCGTTGGTGCCATGCCCCAAGGTTCCAG
CCCCAGCACAGACTTCAGAGGAGCTAAGCTGCACACTTCCAGGCCTCTGCTGTCAGGCAGCTGAGAATCTGACTGCCTCTCCTCCCCTAT
TACAATTCATGTTTAAAGTCATAGTCGCCCAGGAAAGAAAATAGAGAGGGGCACACTTTGTGTGTGTACCTAGTACATAAGAAAGTAGAA
GGAATCAGCTGGGTTTGGGGGTTGCCTTTTGTTTTGGGGCAGGTCTGGGTTTTTGTTTTGGGAGGGGGTGGGGGGAGGGTAAAAAATGGG

>66648_66648_21_PMM2-RBFOX1_PMM2_chr16_8906963_ENST00000569958_RBFOX1_chr16_7568149_ENST00000422070_length(amino acids)=495AA_BP=122
MAAPGPALCLFDVDGTLTAPRQKITKEMDDFLQKLRQKIKIGVVGGSDFEKVQEQLGNDENIRQKFVADLRKEFAGKGLTFSIGGQISFD
VFPDGWDKRYCLRHVENDGYKTIYFFGDKTMPGNQEAAAAPDTMAQPYASAQFAPPQNGIPAEYTAPHPHPAPEYTGQTTVPEHTLNLYP
PAQTHSEQSPADTSAQTVSGTATQTDDAAPTDGQPQTQPSENTENKSQPKRLHVSNIPFRFRDPDLRQMFGQFGKILDVEIIFNERGSKG
FGFVTFENSADADRAREKLHGTVVEGRKIEVNNATARVMTNKKTVNPYTNGWKLNPVVGAVYSPEFYAGTVLLCQANQEGSSMYSAPSSL
VYTSAMPGFPYPAATAAAAYRGAHLRGRGRTVYNTFRAAAPPPPIPAYGGVVYQDGFYGADIYGGYAAYRYAQPTPATAAAYSDSYGRVY

--------------------------------------------------------------
>66648_66648_22_PMM2-RBFOX1_PMM2_chr16_8906963_ENST00000569958_RBFOX1_chr16_7568149_ENST00000535565_length(transcript)=1525nt_BP=382nt
GCTAGAAACTGGGGACATGGCAGCGCCTGGCCCAGCGCTCTGCCTCTTCGACGTGGATGGGACCCTCACCGCCCCGCGGCAGAAAATTAC
CAAAGAAATGGATGACTTCCTACAAAAATTGAGGCAGAAGATCAAAATCGGAGTGGTAGGCGGATCGGACTTTGAGAAAGTGCAGGAGCA
ACTGGGAAATGATGAAAATATAAGACAAAAGTTTGTAGCAGATCTACGGAAAGAGTTTGCTGGAAAAGGCCTCACGTTTTCCATAGGAGG
CCAGATCAGCTTTGATGTCTTTCCTGATGGATGGGACAAGAGATACTGTCTGCGACATGTGGAAAATGACGGTTATAAGACCATTTATTT
CTTTGGAGACAAAACTATGCCAGGTAATCAGGAAGCAGCCGCTGCCCCTGACACAATGGCTCAGCCTTACGCTTCGGCCCAGTTTGCTCC
CCCGCAGAACGGTATCCCCGCGGAATACACGGCCCCTCATCCCCACCCCGCGCCAGAGTACACAGGCCAGACCACGGTTCCCGAGCACAC
ATTAAACCTGTACCCTCCCGCCCAGACGCACTCCGAGCAGAGCCCGGCGGACACGAGCGCTCAGACCGTCTCTGGCACCGCCACACAATT
TGGTAAAATCTTAGATGTTGAAATTATTTTTAATGAGCGAGGCTCAAAGGTAAATAATGCCACAGCACGTGTAATGACAAATAAAAAGAC
CGTCAACCCTTATACAAATGGCTGGAAATTGAATCCAGTTGTGGGTGCAGTCTACAGTCCCGAATTCTATGCAGGCACGGTCCTGTTGTG
CCAGGCCAACCAGGAGGGATCTTCCATGTACAGTGCCCCCAGTTCACTTGTATATACTTCTGCAATGCCAGGCTTCCCGTATCCAGCAGC
CACCGCCGCGGCCGCCTACCGAGGGGCGCACCTGCGAGGCCGCGGTCGCACCGTGTACAACACCTTCAGGGCCGCGGCGCCCCCGCCCCC
GATCCCGGCCTACGGCGGTGTTGTTTACCAGGATGGATTTTATGGTGCAGACATTTATGGTGGTTATGCTGCATACCGCTACGCCCAGCC
TACCCCTGCCACTGCCGCTGCCTACAGTGACAGAAATCAGTTCGTCTTCGTTGCAGCAGATGAAATTTCTTGTAACACCTCTGCAGTTAC
GGACGAGTTTATGCTGCCGACCCCTACCACCACGCACTTGCTCCAGCCCCCACCTACGGCGTTGGTGCCATGCCCCAAGGTTCCAGCCCC
AGCACAGACTTCAGAGGAGCTAAGCTGCACACTTCCAGGCCTCTGCTGTCAGGCAGCTGAGAATCTGACTGCCTCTCCTCCCCTATTACA
ATTCATGTTTAAAGTCATAGTCGCCCAGGAAAGAAAATAGAGAGGGGCACACTTTGTGTGTGTACCTAGTACATAAGAAAGTAGAAGGAA

>66648_66648_22_PMM2-RBFOX1_PMM2_chr16_8906963_ENST00000569958_RBFOX1_chr16_7568149_ENST00000535565_length(amino acids)=457AA_BP=122
MAAPGPALCLFDVDGTLTAPRQKITKEMDDFLQKLRQKIKIGVVGGSDFEKVQEQLGNDENIRQKFVADLRKEFAGKGLTFSIGGQISFD
VFPDGWDKRYCLRHVENDGYKTIYFFGDKTMPGNQEAAAAPDTMAQPYASAQFAPPQNGIPAEYTAPHPHPAPEYTGQTTVPEHTLNLYP
PAQTHSEQSPADTSAQTVSGTATQFGKILDVEIIFNERGSKVNNATARVMTNKKTVNPYTNGWKLNPVVGAVYSPEFYAGTVLLCQANQE
GSSMYSAPSSLVYTSAMPGFPYPAATAAAAYRGAHLRGRGRTVYNTFRAAAPPPPIPAYGGVVYQDGFYGADIYGGYAAYRYAQPTPATA
AAYSDRNQFVFVAADEISCNTSAVTDEFMLPTPTTTHLLQPPPTALVPCPKVPAPAQTSEELSCTLPGLCCQAAENLTASPPLLQFMFKV

--------------------------------------------------------------
>66648_66648_23_PMM2-RBFOX1_PMM2_chr16_8906963_ENST00000569958_RBFOX1_chr16_7568149_ENST00000547372_length(transcript)=3444nt_BP=382nt
GCTAGAAACTGGGGACATGGCAGCGCCTGGCCCAGCGCTCTGCCTCTTCGACGTGGATGGGACCCTCACCGCCCCGCGGCAGAAAATTAC
CAAAGAAATGGATGACTTCCTACAAAAATTGAGGCAGAAGATCAAAATCGGAGTGGTAGGCGGATCGGACTTTGAGAAAGTGCAGGAGCA
ACTGGGAAATGATGAAAATATAAGACAAAAGTTTGTAGCAGATCTACGGAAAGAGTTTGCTGGAAAAGGCCTCACGTTTTCCATAGGAGG
CCAGATCAGCTTTGATGTCTTTCCTGATGGATGGGACAAGAGATACTGTCTGCGACATGTGGAAAATGACGGTTATAAGACCATTTATTT
CTTTGGAGACAAAACTATGCCAGGTAATCAGGAAGCAGCCGCTGCCCCTGACACAATGGCTCAGCCTTACGCTTCGGCCCAGTTTGCTCC
CCCGCAGAACGGTATCCCCGCGGAATACACGGCCCCTCATCCCCACCCCGCGCCAGAGTACACAGGCCAGACCACGGTTCCCGAGCACAC
ATTAAACCTGTACCCTCCCGCCCAGACGCACTCCGAGCAGAGCCCGGCGGACACGAGCGCTCAGACCGTCTCTGGCACCGCCACACAGAC
AGATGACGCAGCACCGACGGATGGCCAGCCCCAGACACAACCTTCTGAAAACACGGAAAACAAGTCTCAGCCCAAGCGGCTGCATGTCTC
CAATATCCCCTTCAGGTTCCGGGATCCGGACCTCAGACAAATGTTTGGTCAATTTGGTAAAATCTTAGATGTTGAAATTATTTTTAATGA
GCGAGGCTCAAAGGGATTTGGTTTCGTAACTTTCGAAAATAGTGCCGATGCGGACAGGGCGAGGGAGAAATTACACGGCACCGTGGTAGA
GGGCCGTAAAATCGAGGTAAATAATGCCACAGCACGTGTAATGACAAATAAAAAGACCGTCAACCCTTATACAAATGGCTGGAAATTGAA
TCCAGTTGTGGGTGCAGTCTACAGTCCCGAATTCTATGCAGGCACGGTCCTGTTGTGCCAGGCCAACCAGGAGGGATCTTCCATGTACAG
TGCCCCCAGTTCACTTGTATATACTTCTGCAATGCCAGGCTTCCCGTATCCAGCAGCCACCGCCGCGGCCGCCTACCGAGGGGCGCACCT
GCGAGGCCGCGGTCGCACCGTGTACAACACCTTCAGGGCCGCGGCGCCCCCGCCCCCGATCCCGGCCTACGGCGGTGTTGTTTACCAGGA
TGGATTTTATGGTGCAGACATTTATGGTGGTTATGCTGCATACCGCTACGCCCAGCCTACCCCTGCCACTGCCGCTGCCTACAGTGACAG
AAATCAGTTCGTCTTCGTTGCAGCAGATGAAATTTCTTGTAACACCTCTGCAGTTACGGACGAGTTTATGCTGCCGACCCCTACCACCAC
GCACTTGCTCCAGCCCCCACCTACGGCGTTGGTGCCATGCCCCAAGGTTCCAGCCCCAGCACAGACTTCAGAGGAGCTAAGCTGCACACT
TCCAGGCCTCTGCTGTCAGGCAGCTGAGAATCTGACTGCCTCTCCTCCCCTATTACAATTCATGTTTAAAGTCATAGTCGCCCAGGAAAG
AAAATAGAGAGGGGCACACTTTGTGTGTGTACCTAGTACATAAGAAAGTAGAAGGAATCAGCTGGGTTTGGGGGTTGCCTTTTGTTTTGG
GGCAGGTCTGGGTTTTTGTTTTGGGAGGGGGTGGGGGGAGGGTAAAAAATGGGAGGTAAGGGTGGGGTGAACTTGCCTGTACTTGTTCAA
ACTTCTATGCACTGAAACTCTTGAGTACAGTAAGACGTGCCCATCACGTGAGAGCATATGCAATCATTACAAAGCTTTGGCATGCAGTTT
TCTGCTTGGATCAAGAATATCAGTCCTTACCCTAAAAATGAATCCCCATAGGCATTCATTTGAATTGCCAATACTTTTAGAAAAAGGAAA
TCGTTAAGTGCCACCTTGTAGCCATTAAAACCATGGCCGGACAGTTCACTGAAGCTCAGTCATAGAAATTCAGCCATGATTTGGAAGCAT
TGTTTTGCACAAGCTTAATTACATCAAGCAATTCATCTGTACAACTCCACAACTCCCTTCTCAAGATCAGATTCCATACAGCTTACAGAG
CCAAGTTAAGTAAGAAGTAGGTTGAGATTTTCATCCCAATTCTGCATTCAACAACTCTGCTTCAACACCTAGTCCACATGAGGAATGTGT
TGGAGAGTTGAATTACATTCAACAACTGGTCCAAATTCAACCTCAAGTGCAGATTATTCTGTTATAAAAAAATGAGACAGTGAAAATCCT
TCCATTGTCCAGCTTATAATAGAGTCCTTTTAGCTAAGAGGACTGGCTGACAGAATTTGGTTTTGCAGGGAATTTCTTTAGGAGGAGCTA
TTGGGGAAGGTCAGGAATGGCCCTATCTTTAGTTCTCCAAGAATGACCTGGGATGGGTAGGGGGTGCCTCCATTTCGGTTGGTTTTGAGT
GTCTATTTTTCACATTAGTCTTTTTGATGATCCACATGTTGCAAAAGGAAAATGTAAAAAACACACCCCTCAAATTGCTTTGTTTCAGAA
TGCTTTTGCACCTTTGACTGATGCCAAGACTAGGAGCCATGCTGATGATGTGGGTCTCGTTCTTTCTTCATTGCAGGCTAGTATATACCG
AGGGGGATACAACCGTTTTGCTCCATACTAAATGACAAAACCATAAAAACCTTCCAATGTGGGGAGAAAGGAAGCTTTCCGAGGCCTGAG
TATTGCAATACATGCAGTAGTACATCATTTTAGCAACTCTAAAAAAAAAAAAAATACAAATAAAAAGGAAAAAAAATTACATTTTTTATC
TTATACCTCAGATATTTTGTTCTGTGTATTTTAATATTGTGGGTCTTTAATTTCTGAAGGTTCCGTAGTTTGGTTGCTGGCTGTAGGAGT
TTTTGTGGTTGATCTAGACAGATGCTAGATAATGAATAAAAACTGGTTTAGGGCCATATCCAGAGTGCTATATTATGTAAATGAATTATA
TATGCTGAATATTAAGCTACTGGGGTTATCAGCTATTTGGGAAGAGTGTAAGTGACTACAGTAGTCATTTTTTTCTGCACCTGCATTATT
TTATTTTGCGAAAGGGGAGGTTGGGAGGGGCTTAGGGGATTGGAACTGGGGTTTGGCTGAAAGAAAAAAAAAAAAATGTAACTGATGAAT
CTAAACGACCCACTGCACCAACAATCATTTATCAATGGTTCTAAGTTACTCATTGCCAGTTCAAGCCAAAGGTCATGTTGTTAAGGGGGT
GCTTCTAGTAGCACTTGTGCATCTGAGTTGAATGAAGCTGTGCAAACCCACCCTTTAAACCATTCCACCCGGCAGTATTCAGCTTCTTAA

>66648_66648_23_PMM2-RBFOX1_PMM2_chr16_8906963_ENST00000569958_RBFOX1_chr16_7568149_ENST00000547372_length(amino acids)=536AA_BP=122
MAAPGPALCLFDVDGTLTAPRQKITKEMDDFLQKLRQKIKIGVVGGSDFEKVQEQLGNDENIRQKFVADLRKEFAGKGLTFSIGGQISFD
VFPDGWDKRYCLRHVENDGYKTIYFFGDKTMPGNQEAAAAPDTMAQPYASAQFAPPQNGIPAEYTAPHPHPAPEYTGQTTVPEHTLNLYP
PAQTHSEQSPADTSAQTVSGTATQTDDAAPTDGQPQTQPSENTENKSQPKRLHVSNIPFRFRDPDLRQMFGQFGKILDVEIIFNERGSKG
FGFVTFENSADADRAREKLHGTVVEGRKIEVNNATARVMTNKKTVNPYTNGWKLNPVVGAVYSPEFYAGTVLLCQANQEGSSMYSAPSSL
VYTSAMPGFPYPAATAAAAYRGAHLRGRGRTVYNTFRAAAPPPPIPAYGGVVYQDGFYGADIYGGYAAYRYAQPTPATAAAYSDRNQFVF

--------------------------------------------------------------
>66648_66648_24_PMM2-RBFOX1_PMM2_chr16_8906963_ENST00000569958_RBFOX1_chr16_7568149_ENST00000550418_length(transcript)=1644nt_BP=382nt
GCTAGAAACTGGGGACATGGCAGCGCCTGGCCCAGCGCTCTGCCTCTTCGACGTGGATGGGACCCTCACCGCCCCGCGGCAGAAAATTAC
CAAAGAAATGGATGACTTCCTACAAAAATTGAGGCAGAAGATCAAAATCGGAGTGGTAGGCGGATCGGACTTTGAGAAAGTGCAGGAGCA
ACTGGGAAATGATGAAAATATAAGACAAAAGTTTGTAGCAGATCTACGGAAAGAGTTTGCTGGAAAAGGCCTCACGTTTTCCATAGGAGG
CCAGATCAGCTTTGATGTCTTTCCTGATGGATGGGACAAGAGATACTGTCTGCGACATGTGGAAAATGACGGTTATAAGACCATTTATTT
CTTTGGAGACAAAACTATGCCAGGTAATCAGGAAGCAGCCGCTGCCCCTGACACAATGGCTCAGCCTTACGCTTCGGCCCAGTTTGCTCC
CCCGCAGAACGGTATCCCCGCGGAATACACGGCCCCTCATCCCCACCCCGCGCCAGAGTACACAGGCCAGACCACGGTTCCCGAGCACAC
ATTAAACCTGTACCCTCCCGCCCAGACGCACTCCGAGCAGAGCCCGGCGGACACGAGCGCTCAGACCGTCTCTGGCACCGCCACACAGAC
AGATGACGCAGCACCGACGGATGGCCAGCCCCAGACACAACCTTCTGAAAACACGGAAAACAAGTCTCAGCCCAAGCGGCTGCATGTCTC
CAATATCCCCTTCAGGTTCCGGGATCCGGACCTCAGACAAATGTTTGGTCAATTTGGTAAAATCTTAGATGTTGAAATTATTTTTAATGA
GCGAGGCTCAAAGGGATTTGGTTTCGTAACTTTCGAAAATAGTGCCGATGCGGACAGGGCGAGGGAGAAATTACACGGCACCGTGGTAGA
GGGCCGTAAAATCGAGGTAAATAATGCCACAGCACGTGTAATGACAAATAAAAAGACCGTCAACCCTTATACAAATGGCTGGAAATTGAA
TCCAGTTGTGGGTGCAGTCTACAGTCCCGAATTCTATGCAGGCACGGTCCTGTTGTGCCAGGCCAACCAGGAGGGATCTTCCATGTACAG
TGCCCCCAGTTCACTTGTATATACTTCTGCAATGCCAGGCTTCCCGTATCCAGCAGCCACCGCCGCGGCCGCCTACCGAGGGGCGCACCT
GCGAGGCCGCGGTCGCACCGTGTACAACACCTTCAGGGCCGCGGCGCCCCCGCCCCCGATCCCGGCCTACGGCGGTGTTGTTTACCAGGA
TGGATTTTATGGTGCAGACATTTATGGTGGTTATGCTGCATACCGCTACGCCCAGCCTACCCCTGCCACTGCCGCTGCCTACAGTGACAG
TTACGGACGAGTTTATGCTGCCGACCCCTACCACCACGCACTTGCTCCAGCCCCCACCTACGGCGTTGGTGCCATGAATGCTTTTGCACC
TTTGACTGATGCCAAGACTAGGAGCCATGCTGATGATGTGGGTCTCGTTCTTTCTTCATTGCAGGCTAGTATATACCGAGGGGGATACAA
CCGTTTTGCTCCATACTAAATGACAAAACCATAAAAACCTTCCAATGTGGGGAGAAAGGAAGCTTTCCGAGGCCTGAGTATTGCAATACA

>66648_66648_24_PMM2-RBFOX1_PMM2_chr16_8906963_ENST00000569958_RBFOX1_chr16_7568149_ENST00000550418_length(amino acids)=510AA_BP=122
MAAPGPALCLFDVDGTLTAPRQKITKEMDDFLQKLRQKIKIGVVGGSDFEKVQEQLGNDENIRQKFVADLRKEFAGKGLTFSIGGQISFD
VFPDGWDKRYCLRHVENDGYKTIYFFGDKTMPGNQEAAAAPDTMAQPYASAQFAPPQNGIPAEYTAPHPHPAPEYTGQTTVPEHTLNLYP
PAQTHSEQSPADTSAQTVSGTATQTDDAAPTDGQPQTQPSENTENKSQPKRLHVSNIPFRFRDPDLRQMFGQFGKILDVEIIFNERGSKG
FGFVTFENSADADRAREKLHGTVVEGRKIEVNNATARVMTNKKTVNPYTNGWKLNPVVGAVYSPEFYAGTVLLCQANQEGSSMYSAPSSL
VYTSAMPGFPYPAATAAAAYRGAHLRGRGRTVYNTFRAAAPPPPIPAYGGVVYQDGFYGADIYGGYAAYRYAQPTPATAAAYSDSYGRVY

--------------------------------------------------------------
>66648_66648_25_PMM2-RBFOX1_PMM2_chr16_8906963_ENST00000569958_RBFOX1_chr16_7568149_ENST00000553186_length(transcript)=1563nt_BP=382nt
GCTAGAAACTGGGGACATGGCAGCGCCTGGCCCAGCGCTCTGCCTCTTCGACGTGGATGGGACCCTCACCGCCCCGCGGCAGAAAATTAC
CAAAGAAATGGATGACTTCCTACAAAAATTGAGGCAGAAGATCAAAATCGGAGTGGTAGGCGGATCGGACTTTGAGAAAGTGCAGGAGCA
ACTGGGAAATGATGAAAATATAAGACAAAAGTTTGTAGCAGATCTACGGAAAGAGTTTGCTGGAAAAGGCCTCACGTTTTCCATAGGAGG
CCAGATCAGCTTTGATGTCTTTCCTGATGGATGGGACAAGAGATACTGTCTGCGACATGTGGAAAATGACGGTTATAAGACCATTTATTT
CTTTGGAGACAAAACTATGCCAGGTAATCAGGAAGCAGCCGCTGCCCCTGACACAATGGCTCAGCCTTACGCTTCGGCCCAGTTTGCTCC
CCCGCAGAACGGTATCCCCGCGGAATACACGGCCCCTCATCCCCACCCCGCGCCAGAGTACACAGGCCAGACCACGGTTCCCGAGCACAC
ATTAAACCTGTACCCTCCCGCCCAGACGCACTCCGAGCAGAGCCCGGCGGACACGAGCGCTCAGACCGTCTCTGGCACCGCCACACAGAC
AGATGACGCAGCACCGACGGATGGCCAGCCCCAGACACAACCTTCTGAAAACACGGAAAACAAGTCTCAGCCCAAGCGGCTGCATGTCTC
CAATATCCCCTTCAGGTTCCGGGATCCGGACCTCAGACAAATGTTTGGTCAATTTGGTAAAATCTTAGATGTTGAAATTATTTTTAATGA
GCGAGGCTCAAAGGGATTTGGTTTCGTAACTTTCGAAAATAGTGCCGATGCGGACAGGGCGAGGGAGAAATTACACGGCACCGTGGTAGA
GGGCCGTAAAATCGAGGTAAATAATGCCACAGCACGTGTAATGACAAATAAAAAGACCGTCAACCCTTATACAAATGGCTGGAAATTGAA
TCCAGTTGTGGGTGCAGTCTACAGTCCCGAATTCTATGCAGTGCCAGGCTTCCCGTATCCAGCAGCCACCGCCGCGGCCGCCTACCGAGG
GGCGCACCTGCGAGGCCGCGGTCGCACCGTGTACAACACCTTCAGGGCCGCGGCGCCCCCGCCCCCGATCCCGGCCTACGGCGGTGTTGT
TTACCAGGATGGATTTTATGGTGCAGACATTTATGGTGGTTATGCTGCATACCGCTACGCCCAGCCTACCCCTGCCACTGCCGCTGCCTA
CAGTGACAGTTACGGACGAGTTTATGCTGCCGACCCCTACCACCACGCACTTGCTCCAGCCCCCACCTACGGCGTTGGTGCCATGAATGC
TTTTGCACCTTTGACTGATGCCAAGACTAGGAGCCATGCTGATGATGTGGGTCTCGTTCTTTCTTCATTGCAGGCTAGTATATACCGAGG
GGGATACAACCGTTTTGCTCCATACTAAATGACAAAACCATAAAAACCTTCCAATGTGGGGAGAAAGGAAGCTTTCCGAGGCCTGAGTAT

>66648_66648_25_PMM2-RBFOX1_PMM2_chr16_8906963_ENST00000569958_RBFOX1_chr16_7568149_ENST00000553186_length(amino acids)=483AA_BP=122
MAAPGPALCLFDVDGTLTAPRQKITKEMDDFLQKLRQKIKIGVVGGSDFEKVQEQLGNDENIRQKFVADLRKEFAGKGLTFSIGGQISFD
VFPDGWDKRYCLRHVENDGYKTIYFFGDKTMPGNQEAAAAPDTMAQPYASAQFAPPQNGIPAEYTAPHPHPAPEYTGQTTVPEHTLNLYP
PAQTHSEQSPADTSAQTVSGTATQTDDAAPTDGQPQTQPSENTENKSQPKRLHVSNIPFRFRDPDLRQMFGQFGKILDVEIIFNERGSKG
FGFVTFENSADADRAREKLHGTVVEGRKIEVNNATARVMTNKKTVNPYTNGWKLNPVVGAVYSPEFYAVPGFPYPAATAAAAYRGAHLRG
RGRTVYNTFRAAAPPPPIPAYGGVVYQDGFYGADIYGGYAAYRYAQPTPATAAAYSDSYGRVYAADPYHHALAPAPTYGVGAMNAFAPLT

--------------------------------------------------------------

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Fusion Gene PPI Analysis for PMM2-RBFOX1


check button Go to ChiPPI (Chimeric Protein-Protein interactions) to see the chimeric PPI interaction in

ChiPPI page.


check button Protein-protein interactors with each fusion partner protein in wild-type (BIOGRID-3.4.160)
HgeneHgene's interactorsTgeneTgene's interactors


check button - Retained PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenStill interaction with


check button - Lost PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


check button - Retained PPIs, but lost function due to frame-shift fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


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Related Drugs for PMM2-RBFOX1


check button Drugs targeting genes involved in this fusion gene.
(DrugBank Version 5.1.8 2021-05-08)
PartnerGeneUniProtAccDrugBank IDDrug nameDrug activityDrug typeDrug status

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Related Diseases for PMM2-RBFOX1


check button Diseases associated with fusion partners.
(DisGeNet 4.0)
PartnerGeneDisease IDDisease name# pubmedsSource