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Center for Computational Systems Medicine
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Fusion Gene Summary

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Fusion Gene ORF analysis

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Fusion Genomic Features

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Fusion Protein Features

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Fusion Gene Sequence

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Fusion Gene PPI analysis

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Related Drugs

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Related Diseases

Fusion gene:POLK-SKIV2L2 (FusionGDB2 ID:66960)

Fusion Gene Summary for POLK-SKIV2L2

check button Fusion gene summary
Fusion gene informationFusion gene name: POLK-SKIV2L2
Fusion gene ID: 66960
HgeneTgene
Gene symbol

POLK

SKIV2L2

Gene ID

51426

23517

Gene nameDNA polymerase kappaMtr4 exosome RNA helicase
SynonymsDINB1|DINP|POLQDob1|KIAA0052|Mtr4|SKIV2L2|fSAP118
Cytomap

5q13.3

5q11.2

Type of geneprotein-codingprotein-coding
DescriptionDNA polymerase kappapolymerase (DNA directed) kappaexosome RNA helicase MTR4ATP-dependent RNA helicase DOB1ATP-dependent RNA helicase SKIV2L2ATP-dependent helicase SKIV2L2Ski2 like RNA helicase 2TRAMP-like complex helicasefunctional spliceosome-associated protein 118superkiller viralicidic activity
Modification date2020032020200313
UniProtAcc..
Ensembl transtripts involved in fusion geneENST00000506928, ENST00000241436, 
ENST00000380481, ENST00000504026, 
ENST00000515295, ENST00000352007, 
ENST00000508526, 		ENST00000230640, 
ENST00000545714, ENST00000504388, 
Fusion gene scores* DoF score7 X 6 X 4=1689 X 8 X 7=504
# samples 79
** MAII scorelog2(7/168*10)=-1.26303440583379
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0		log2(9/504*10)=-2.48542682717024
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0
Context

PubMed: POLK [Title/Abstract] AND SKIV2L2 [Title/Abstract] AND fusion [Title/Abstract]

Most frequent breakpointPOLK(74882883)-SKIV2L2(54635838), # samples:1
POLK(74886265)-SKIV2L2(54635838), # samples:1
Anticipated loss of major functional domain due to fusion event.POLK-SKIV2L2 seems lost the major protein functional domain in Tgene partner, which is a essential gene due to the frame-shifted ORF.
* DoF score (Degree of Frequency) = # partners X # break points X # cancer types
** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10)

check button Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez
PartnerGeneGO IDGO termPubMed ID
HgenePOLK

GO:0006281

DNA repair

28297716

HgenePOLK

GO:0006974

cellular response to DNA damage stimulus

28297716

HgenePOLK

GO:0034644

cellular response to UV

28297716

HgenePOLK

GO:0042276

error-prone translesion synthesis

28297716

TgeneSKIV2L2

GO:0006401

RNA catabolic process

29906447


check buttonFusion gene breakpoints across POLK (5'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.
all structure

check buttonFusion gene breakpoints across SKIV2L2 (3'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.
all structure

check button Fusion gene information from two resources (ChiTars 5.0 and ChimerDB 4.0)
* All genome coordinats were lifted-over on hg19.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
SourceDiseaseSampleHgeneHchrHbpHstrandTgeneTchrTbpTstrand
ChimerDB4READTCGA-CL-5918-01APOLKchr5

74882883

+SKIV2L2chr5

54635838

+
ChimerDB4READTCGA-CL-5918-01APOLKchr5

74886265

-SKIV2L2chr5

54635838

+


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Fusion Gene ORF analysis for POLK-SKIV2L2

check button Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
ORFHenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrand
3UTR-3CDSENST00000506928ENST00000230640POLKchr5

74882883

+SKIV2L2chr5

54635838

+
3UTR-3CDSENST00000506928ENST00000230640POLKchr5

74886265

-SKIV2L2chr5

54635838

+
3UTR-3CDSENST00000506928ENST00000545714POLKchr5

74882883

+SKIV2L2chr5

54635838

+
3UTR-3CDSENST00000506928ENST00000545714POLKchr5

74886265

-SKIV2L2chr5

54635838

+
3UTR-intronENST00000506928ENST00000504388POLKchr5

74882883

+SKIV2L2chr5

54635838

+
3UTR-intronENST00000506928ENST00000504388POLKchr5

74886265

-SKIV2L2chr5

54635838

+
5CDS-intronENST00000241436ENST00000504388POLKchr5

74882883

+SKIV2L2chr5

54635838

+
5CDS-intronENST00000241436ENST00000504388POLKchr5

74886265

-SKIV2L2chr5

54635838

+
5CDS-intronENST00000380481ENST00000504388POLKchr5

74882883

+SKIV2L2chr5

54635838

+
5CDS-intronENST00000380481ENST00000504388POLKchr5

74886265

-SKIV2L2chr5

54635838

+
5CDS-intronENST00000504026ENST00000504388POLKchr5

74882883

+SKIV2L2chr5

54635838

+
5CDS-intronENST00000504026ENST00000504388POLKchr5

74886265

-SKIV2L2chr5

54635838

+
5CDS-intronENST00000515295ENST00000504388POLKchr5

74882883

+SKIV2L2chr5

54635838

+
5CDS-intronENST00000515295ENST00000504388POLKchr5

74886265

-SKIV2L2chr5

54635838

+
Frame-shiftENST00000241436ENST00000230640POLKchr5

74886265

-SKIV2L2chr5

54635838

+
Frame-shiftENST00000241436ENST00000545714POLKchr5

74886265

-SKIV2L2chr5

54635838

+
Frame-shiftENST00000380481ENST00000230640POLKchr5

74886265

-SKIV2L2chr5

54635838

+
Frame-shiftENST00000380481ENST00000545714POLKchr5

74886265

-SKIV2L2chr5

54635838

+
Frame-shiftENST00000504026ENST00000230640POLKchr5

74886265

-SKIV2L2chr5

54635838

+
Frame-shiftENST00000504026ENST00000545714POLKchr5

74886265

-SKIV2L2chr5

54635838

+
Frame-shiftENST00000515295ENST00000230640POLKchr5

74886265

-SKIV2L2chr5

54635838

+
Frame-shiftENST00000515295ENST00000545714POLKchr5

74886265

-SKIV2L2chr5

54635838

+
In-frameENST00000241436ENST00000230640POLKchr5

74882883

+SKIV2L2chr5

54635838

+
In-frameENST00000241436ENST00000545714POLKchr5

74882883

+SKIV2L2chr5

54635838

+
In-frameENST00000380481ENST00000230640POLKchr5

74882883

+SKIV2L2chr5

54635838

+
In-frameENST00000380481ENST00000545714POLKchr5

74882883

+SKIV2L2chr5

54635838

+
In-frameENST00000504026ENST00000230640POLKchr5

74882883

+SKIV2L2chr5

54635838

+
In-frameENST00000504026ENST00000545714POLKchr5

74882883

+SKIV2L2chr5

54635838

+
In-frameENST00000515295ENST00000230640POLKchr5

74882883

+SKIV2L2chr5

54635838

+
In-frameENST00000515295ENST00000545714POLKchr5

74882883

+SKIV2L2chr5

54635838

+
intron-3CDSENST00000352007ENST00000230640POLKchr5

74882883

+SKIV2L2chr5

54635838

+
intron-3CDSENST00000352007ENST00000230640POLKchr5

74886265

-SKIV2L2chr5

54635838

+
intron-3CDSENST00000352007ENST00000545714POLKchr5

74882883

+SKIV2L2chr5

54635838

+
intron-3CDSENST00000352007ENST00000545714POLKchr5

74886265

-SKIV2L2chr5

54635838

+
intron-3CDSENST00000508526ENST00000230640POLKchr5

74882883

+SKIV2L2chr5

54635838

+
intron-3CDSENST00000508526ENST00000230640POLKchr5

74886265

-SKIV2L2chr5

54635838

+
intron-3CDSENST00000508526ENST00000545714POLKchr5

74882883

+SKIV2L2chr5

54635838

+
intron-3CDSENST00000508526ENST00000545714POLKchr5

74886265

-SKIV2L2chr5

54635838

+
intron-intronENST00000352007ENST00000504388POLKchr5

74882883

+SKIV2L2chr5

54635838

+
intron-intronENST00000352007ENST00000504388POLKchr5

74886265

-SKIV2L2chr5

54635838

+
intron-intronENST00000508526ENST00000504388POLKchr5

74882883

+SKIV2L2chr5

54635838

+
intron-intronENST00000508526ENST00000504388POLKchr5

74886265

-SKIV2L2chr5

54635838

+

check buttonORFfinder result based on the fusion transcript sequence of in-frame fusion genes.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandSeq length
(transcript)		BP loci
(transcript)		Predicted start
(transcript)		Predicted stop
(transcript)		Seq length
(amino acids)
ENST00000241436POLKchr574882883+ENST00000230640SKIV2L2chr554635838+4854143117240441290
ENST00000241436POLKchr574882883+ENST00000545714SKIV2L2chr554635838+4379143117240441290
ENST00000515295POLKchr574882883+ENST00000230640SKIV2L2chr554635838+469512721338851290
ENST00000515295POLKchr574882883+ENST00000545714SKIV2L2chr554635838+422012721338851290
ENST00000504026POLKchr574882883+ENST00000230640SKIV2L2chr554635838+46821259038721290
ENST00000504026POLKchr574882883+ENST00000545714SKIV2L2chr554635838+42071259038721290
ENST00000380481POLKchr574882883+ENST00000230640SKIV2L2chr554635838+4796137338439861200
ENST00000380481POLKchr574882883+ENST00000545714SKIV2L2chr554635838+4321137338439861200

check buttonDeepORF prediction of the coding potential based on the fusion transcript sequence of in-frame fusion genes. DeepORF is a coding potential classifier based on convolutional neural network by comparing the real Ribo-seq data. If the no-coding score < 0.5 and coding score > 0.5, then the in-frame fusion transcript is predicted as being likely translated.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandNo-coding scoreCoding score
ENST00000241436ENST00000230640POLKchr574882883+SKIV2L2chr554635838+0.0003944460.9996056
ENST00000241436ENST00000545714POLKchr574882883+SKIV2L2chr554635838+0.0004613130.99953866
ENST00000515295ENST00000230640POLKchr574882883+SKIV2L2chr554635838+0.0003318940.9996681
ENST00000515295ENST00000545714POLKchr574882883+SKIV2L2chr554635838+0.0003871710.99961287
ENST00000504026ENST00000230640POLKchr574882883+SKIV2L2chr554635838+0.0003331030.9996669
ENST00000504026ENST00000545714POLKchr574882883+SKIV2L2chr554635838+0.0003894470.9996106
ENST00000380481ENST00000230640POLKchr574882883+SKIV2L2chr554635838+0.0005127310.9994873
ENST00000380481ENST00000545714POLKchr574882883+SKIV2L2chr554635838+0.0005902870.9994097

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Fusion Genomic Features for POLK-SKIV2L2


check buttonFusionAI prediction of the potential fusion gene breakpoint based on the pre-mature RNA sequence context (+/- 5kb of individual partner genes, total 20kb length sequence). FusionAI is a fusion gene breakpoint classifier based on convolutional neural network by comparing the fusion positive and negative sequence context of ~ 20K fusion gene data. From here, we can have the relative potentency of the 20K genomic sequence how individual sequnce will be likely used as the gene fusion breakpoints.
HgeneHchrHbpHstrandTgeneTchrTbpTstrand1-pp (fusion gene breakpoint)
POLKchr574882883+SKIV2L2chr554635837+0.0021994790.9978005
POLKchr574882883+SKIV2L2chr554635837+0.0021994790.9978005

check buttonDistribution of 44 human genomic features loci across 20kb length fusion breakpoint regions. We integrated a total of 44 different types of human genomic feature loci information across five big categories including virus integration sites, repeats, structural variants, chromatin states, and gene expression regulation. More details are in help page.
genomic feature

check buttonDistribution of 44 human genomic features loci across 20kb length fusion breakpoint regions that are ovelapped with the top 1% feature importance score regions. More details are in help page.
genomic feature of top 1%

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Fusion Protein Features for POLK-SKIV2L2


check button Four levels of functional features of fusion genes
Go to FGviewer search page for the most frequent breakpoint (https://ccsmweb.uth.edu/FGviewer/chr5:74882883/chr5:54635838)
- FGviewer provides the online visualization of the retention search of the protein functional features across DNA, RNA, protein, and pathological levels.
- How to search
1. Put your fusion gene symbol.
2. Press the tab key until there will be shown the breakpoint information filled.
4. Go down and press 'Search' tab twice.
4. Go down to have the hyperlink of the search result.
5. Click the hyperlink.
6. See the FGviewer result for your fusion gene.
FGviewer

check buttonMain function of each fusion partner protein. (from UniProt)
HgeneTgene
..
FUNCTION: Transcriptional activator which is required for calcium-dependent dendritic growth and branching in cortical neurons. Recruits CREB-binding protein (CREBBP) to nuclear bodies. Component of the CREST-BRG1 complex, a multiprotein complex that regulates promoter activation by orchestrating a calcium-dependent release of a repressor complex and a recruitment of an activator complex. In resting neurons, transcription of the c-FOS promoter is inhibited by BRG1-dependent recruitment of a phospho-RB1-HDAC1 repressor complex. Upon calcium influx, RB1 is dephosphorylated by calcineurin, which leads to release of the repressor complex. At the same time, there is increased recruitment of CREBBP to the promoter by a CREST-dependent mechanism, which leads to transcriptional activation. The CREST-BRG1 complex also binds to the NR2B promoter, and activity-dependent induction of NR2B expression involves a release of HDAC1 and recruitment of CREBBP (By similarity). {ECO:0000250}.FUNCTION: Transcriptional activator which is required for calcium-dependent dendritic growth and branching in cortical neurons. Recruits CREB-binding protein (CREBBP) to nuclear bodies. Component of the CREST-BRG1 complex, a multiprotein complex that regulates promoter activation by orchestrating a calcium-dependent release of a repressor complex and a recruitment of an activator complex. In resting neurons, transcription of the c-FOS promoter is inhibited by BRG1-dependent recruitment of a phospho-RB1-HDAC1 repressor complex. Upon calcium influx, RB1 is dephosphorylated by calcineurin, which leads to release of the repressor complex. At the same time, there is increased recruitment of CREBBP to the promoter by a CREST-dependent mechanism, which leads to transcriptional activation. The CREST-BRG1 complex also binds to the NR2B promoter, and activity-dependent induction of NR2B expression involves a release of HDAC1 and recruitment of CREBBP (By similarity). {ECO:0000250}.

check buttonRetention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at

download page


* Minus value of BPloci means that the break pointn is located before the CDS.
- In-frame and retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
HgenePOLKchr5:74882883chr5:54635838ENST00000241436+1015103_358419871.0DomainNote=UmuC
HgenePOLKchr5:74882883chr5:54635838ENST00000504026+912103_358419445.3333333333333DomainNote=UmuC
HgenePOLKchr5:74882883chr5:54635838ENST00000515295+910103_358419473.0DomainNote=UmuC
TgeneSKIV2L2chr5:74882883chr5:54635838ENST00000230640427405_5771711043.0DomainHelicase C-terminal
TgeneSKIV2L2chr5:74882883chr5:54635838ENST00000230640427252_2551711043.0MotifNote=DEIH box

- In-frame and not-retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
HgenePOLKchr5:74882883chr5:54635838ENST00000352007+110103_3580673.0DomainNote=UmuC
HgenePOLKchr5:74882883chr5:54635838ENST00000380481+1015103_358329781.0DomainNote=UmuC
HgenePOLKchr5:74882883chr5:54635838ENST00000508526+19103_3580673.0DomainNote=UmuC
HgenePOLKchr5:74882883chr5:54635838ENST00000241436+1015621_651419871.0Zinc fingerUBZ4-type 1
HgenePOLKchr5:74882883chr5:54635838ENST00000241436+1015776_806419871.0Zinc fingerUBZ4-type 2
HgenePOLKchr5:74882883chr5:54635838ENST00000352007+110621_6510673.0Zinc fingerUBZ4-type 1
HgenePOLKchr5:74882883chr5:54635838ENST00000352007+110776_8060673.0Zinc fingerUBZ4-type 2
HgenePOLKchr5:74882883chr5:54635838ENST00000380481+1015621_651329781.0Zinc fingerUBZ4-type 1
HgenePOLKchr5:74882883chr5:54635838ENST00000380481+1015776_806329781.0Zinc fingerUBZ4-type 2
HgenePOLKchr5:74882883chr5:54635838ENST00000504026+912621_651419445.3333333333333Zinc fingerUBZ4-type 1
HgenePOLKchr5:74882883chr5:54635838ENST00000504026+912776_806419445.3333333333333Zinc fingerUBZ4-type 2
HgenePOLKchr5:74882883chr5:54635838ENST00000508526+19621_6510673.0Zinc fingerUBZ4-type 1
HgenePOLKchr5:74882883chr5:54635838ENST00000508526+19776_8060673.0Zinc fingerUBZ4-type 2
HgenePOLKchr5:74882883chr5:54635838ENST00000515295+910621_651419473.0Zinc fingerUBZ4-type 1
HgenePOLKchr5:74882883chr5:54635838ENST00000515295+910776_806419473.0Zinc fingerUBZ4-type 2
TgeneSKIV2L2chr5:74882883chr5:54635838ENST00000230640427148_3041711043.0DomainHelicase ATP-binding
TgeneSKIV2L2chr5:74882883chr5:54635838ENST00000230640427161_1681711043.0Nucleotide bindingATP


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Fusion Gene Sequence for POLK-SKIV2L2


check button For in-frame fusion transcripts, we provide the fusion transcript sequences and fusion amino acid sequences. To have fusion amino acid sequence, we ran ORFfinder and chose the longest ORF among the all predicted ones.
>66960_66960_1_POLK-SKIV2L2_POLK_chr5_74882883_ENST00000241436_SKIV2L2_chr5_54635838_ENST00000230640_length(transcript)=4854nt_BP=1431nt
TACCTCCGGCTCTCCCGGGTGACGACGGGTAGAAAAGCAGGAGGAGCGGAGAAAGGAGAGGGCGGGGTAGGGATGCAGCTGTGCTGCATT
CTGGGAAGGGCGTTGGTCCGTCGCTCGCGCAGCCTCCTGGGAGTTGTAGTCGCGATCCTGAGGTAACGGATAAGTTTATACCATGGATAG
CACAAAGGAGAAGTGTGACAGTTACAAAGATGATCTTCTGCTTAGGATGGGACTTAATGATAATAAAGCAGGAATGGAAGGATTAGATAA
AGAGAAAATTAACAAAATTATAATGGAAGCCACGAAGGGGTCCAGATTTTATGGAAATGAGCTCAAGAAAGAAAAGCAAGTCAACCAACG
AATTGAAAATATGATGCAACAAAAAGCTCAAATCACCAGCCAACAGCTAAGAAAAGCACAATTACAGGTTGACAGATTTGCAATGGAATT
AGAACAAAGCCGAAATTTGAGCAATACCATAGTGCACATTGACATGGATGCTTTCTATGCAGCTGTAGAAATGAGGGACAATCCAGAATT
GAAGGATAAACCCATTGCTGTAGGATCAATGAGTATGCTGTCTACTTCAAATTACCATGCAAGGAGATTTGGTGTTCGTGCAGCCATGCC
AGGATTTATTGCTAAGAGGCTGTGCCCACAACTTATAATAGTGCCCCCCAACTTTGACAAATACCGAGCTGTGAGTAAAGAGGTTAAGGA
AATACTTGCTGATTATGATCCCAATTTTATGGCCATGAGTCTTGATGAAGCCTACTTGAATATAACAAAGCACTTAGAAGAAAGACAAAA
TTGGCCTGAGGATAAAAGAAGGTATTTCATCAAAATGGGAAGCTCTGTAGAAAATGATAATCCAGGAAAGGAAGTTAATAAACTGAGTGA
GCATGAACGATCCATCTCTCCACTACTTTTTGAAGAGAGTCCTTCTGATGTGCAGCCCCCAGGAGATCCTTTCCAAGTGAACTTTGAAGA
ACAAAACAATCCTCAAATACTCCAAAACTCAGTTGTTTTTGGAACATCAGCCCAGGAAGTGGTAAAGGAAATTCGTTTCAGAATTGAGCA
GAAAACAACACTGACAGCCAGTGCAGGCATTGCCCCAAATACAATGTTAGCAAAAGTATGCAGTGATAAGAATAAACCAAATGGACAATA
CCAAATTCTTCCCAATAGACAAGCTGTGATGGACTTCATCAAGGATTTACCCATTAGAAAGGTTTCTGGAATAGGAAAAGTTACAGAGAA
AATGTTAAAGGCCCTTGGAATTATTACATGTACAGAACTTTACCAACAGAGGGCATTGCTTTCTCTCCTTTTCTCTGAAACATCTTGGCA
TTATTTCCTTCATATCTCCTTGGGTCTAGGTTCAACACACCTGACGAGGGATGGAGAGAGGAAAAGTATGAGCGTTGAGAGGTATGCCAT
TGCATTGGCCTTAAGGGAAAAGCAGCGTGTAATATTTACCAGCCCAATTAAGGCTCTGAGTAACCAAAAATACCGTGAAATGTATGAAGA
ATTTCAAGATGTTGGTTTGATGACTGGTGATGTTACTATTAATCCTACGGCATCTTGTCTTGTTATGACCACAGAGATTTTGAGAAGTAT
GCTTTACAGAGGTTCCGAAGTTATGAGAGAAGTTGCTTGGGTTATATTTGATGAAATTCATTATATGAGAGATTCAGAACGTGGTGTAGT
ATGGGAAGAAACTATTATTTTGCTTCCTGATAACGTCCACTATGTCTTTCTTTCGGCTACTATTCCAAATGCCCGACAGTTTGCTGAATG
GATTTGCCATTTACATAAACAGCCTTGTCATGTTATTTACACAGATTATCGGCCCACTCCATTGCAACACTACATTTTTCCAGCAGGGGG
AGATGGCCTGCATCTTGTGGTTGATGAAAATGGTGACTTCAGAGAAGATAATTTTAATACTGCAATGCAAGTGCTTCGAGATGCAGGTGA
TTTGGCCAAAGGAGACCAGAAAGGGCGGAAAGGAGGAACAAAAGGACCATCAAATGTTTTCAAAATTGTGAAGATGATTATGGAAAGAAA
TTTCCAACCTGTGATTATTTTCAGTTTTAGTAAGAAAGATTGTGAAGCCTATGCACTTCAAATGACCAAATTAGATTTCAACACAGATGA
AGAAAAGAAGATGGTTGAAGAAGTATTCAGTAATGCAATTGATTGCTTATCCGATGAAGATAAAAAACTCCCTCAGGTAGAACATGTACT
TCCTCTTTTGAAGAGGGGAATTGGTATTCACCATGGTGGTTTACTTCCTATTTTGAAAGAAACTATAGAAATTCTCTTTTCTGAAGGATT
GATAAAGGCCTTATTTGCCACGGAGACCTTTGCTATGGGAATTAACATGCCAGCTAGAACTGTTTTATTTACAAATGCCCGCAAATTTGA
TGGGAAGGATTTCCGATGGATTTCTTCTGGTGAATACATTCAGATGTCTGGTCGTGCTGGAAGGAGAGGAATGGATGATAGAGGAATTGT
AATTCTTATGGTAGATGAAAAGATGAGCCCAACAATTGGAAAACAATTACTTAAGGGCTCCGCTGATCCTCTAAATAGTGCTTTCCATTT
GACCTACAACATGGTTTTGAACTTACTACGTGTAGAAGAAATTAATCCTGAGTACATGTTGGAAAAATCCTTCTACCAGTTTCAGCATTA
TAGAGCAATTCCAGGAGTAGTAGAGAAGGTAAAGAATTCAGAAGAACAGTATAATAAAATAGTAATTCCCAATGAAGAAAGTGTGGTTAT
CTATTATAAGATTAGACAGCAGCTTGCCAAATTGGGTAAAGAAATTGAAGAATATATTCACAAACCAAAATACTGCTTACCTTTTCTACA
ACCAGGTCGTTTGGTAAAGGTAAAGAATGAAGGAGATGACTTTGGCTGGGGAGTAGTGGTGAATTTCTCAAAAAAGTCAAATGTTAAGCC
TAACTCTGGTGAACTGGATCCTTTGTATGTAGTAGAAGTACTTCTGCGCTGTAGCAAAGAGAGCTTGAAAAATTCAGCTACAGAAGCTGC
AAAACCAGCTAAACCTGATGAGAAAGGAGAGATGCAGGTTGTCCCAGTTTTGGTGCATCTCCTGTCTGCTATCAGCAGTGTTAGGCTTTA
CATTCCTAAAGACCTTCGGCCGGTGGACAATAGACAGAGTGTTTTAAAATCAATACAGGAAGTTCAGAAACGTTTTCCTGACGGCATCCC
CTTATTAGACCCTATTGATGATATGGGCATTCAAGATCAAGGGCTGAAAAAAGTCATTCAGAAAGTAGAAGCTTTTGAGCATCGAATGTA
TTCTCATCCACTTCACAATGATCCAAATTTGGAAACTGTGTATACGCTTTGTGAAAAAAAAGCACAGATTGCAATAGATATTAAATCTGC
AAAGCGAGAACTGAAGAAAGCAAGAACAGTCCTACAAATGGATGAACTCAAATGTCGCAAACGTGTTTTAAGAAGGTTGGGATTTGCTAC
TTCTTCTGATGTAATAGAGATGAAAGGACGAGTGGCTTGTGAGATAAGCAGTGCTGATGAGCTCCTTCTAACTGAGATGATGTTTAATGG
CCTTTTCAATGACCTTTCTGCAGAACAGGCAACAGCATTATTAAGCTGCTTTGTGTTTCAAGAGAATTCTAGTGAGATGCCCAAATTAAC
AGAACAATTAGCAGGACCACTTCGTCAAATGCAGGAATGTGCTAAAAGAATTGCAAAAGTTTCAGCAGAAGCCAAATTGGAAATTGATGA
GGAAACTTATCTAAGCTCATTTAAACCTCACTTAATGGATGTAGTATATACCTGGGCAACTGGAGCTACATTTGCCCATATCTGCAAAAT
GACAGATGTCTTTGAAGGCAGCATAATTCGTTGTATGAGGCGCCTGGAAGAATTGCTTCGACAAATGTGTCAAGCAGCAAAAGCCATTGG
AAACACTGAGCTGGAAAATAAATTTGCAGAAGGAATCACCAAAATCAAGAGAGATATTGTGTTTGCTGCCAGCCTCTACTTGTAGAGTCA
GCTAAAGGAATGTGAGATTTTAAATTATTGACCACCTGTTTGATTACAGTTGACTACAAATGCCTGCAAGTGTGGATTTGGTTCTCCCAT
ACATTTTAATATGTATTATATTTAAATCAAACATCATTCATAGAAAGCATATTACATACATGTTTATACATAAGCATTACATTTTTTTAA
TAAAAATGTATACAGGTGGGGCACTGTTTTGGTGGAAGGCTTGGAGTTTTTTTAATGAGTTTAGAGCTATTAGATAACCACTGAGTTAAA
GGTAACTATGTACACACAAAGTGTGCATCCAAGAGGCATAGCAGCAGCAGAAGTCTTTAAAGGCTTGTACACCAGGAAGAAAGATGCATC
CTCTTGCCTTGTGGCAATCATTTTCCTTTAGAAAACAGGCCAGCTTCACCTGGGCACCCTGCTGCCTTTCAAGGCTGGTGATTGCTCGGA
TAGTGATTCCCAGTTGTTGGTGTTTCATGCAGAGTTGTATGAGAGTCCTCCTCTTTTCTTTCTTTAAAAGAAGTTCTTTCTTTGAAGAAA
TCCGATACATATACAGCCTACAGTGCAAAATATTTAATGGTATAATTTAGATCAAGTTAAAAACTACATACAAAGTTGTGATCAACAGCA
TCCTAAGATAAATATAAACAAAAGGATATACTTTGAGGTGTACAGATTAAGCATATAAAAAATTAGAGACTAACTGGGATTTTTTAAAGA

>66960_66960_1_POLK-SKIV2L2_POLK_chr5_74882883_ENST00000241436_SKIV2L2_chr5_54635838_ENST00000230640_length(amino acids)=1290AA_BP=419
MDSTKEKCDSYKDDLLLRMGLNDNKAGMEGLDKEKINKIIMEATKGSRFYGNELKKEKQVNQRIENMMQQKAQITSQQLRKAQLQVDRFA
MELEQSRNLSNTIVHIDMDAFYAAVEMRDNPELKDKPIAVGSMSMLSTSNYHARRFGVRAAMPGFIAKRLCPQLIIVPPNFDKYRAVSKE
VKEILADYDPNFMAMSLDEAYLNITKHLEERQNWPEDKRRYFIKMGSSVENDNPGKEVNKLSEHERSISPLLFEESPSDVQPPGDPFQVN
FEEQNNPQILQNSVVFGTSAQEVVKEIRFRIEQKTTLTASAGIAPNTMLAKVCSDKNKPNGQYQILPNRQAVMDFIKDLPIRKVSGIGKV
TEKMLKALGIITCTELYQQRALLSLLFSETSWHYFLHISLGLGSTHLTRDGERKSMSVERYAIALALREKQRVIFTSPIKALSNQKYREM
YEEFQDVGLMTGDVTINPTASCLVMTTEILRSMLYRGSEVMREVAWVIFDEIHYMRDSERGVVWEETIILLPDNVHYVFLSATIPNARQF
AEWICHLHKQPCHVIYTDYRPTPLQHYIFPAGGDGLHLVVDENGDFREDNFNTAMQVLRDAGDLAKGDQKGRKGGTKGPSNVFKIVKMIM
ERNFQPVIIFSFSKKDCEAYALQMTKLDFNTDEEKKMVEEVFSNAIDCLSDEDKKLPQVEHVLPLLKRGIGIHHGGLLPILKETIEILFS
EGLIKALFATETFAMGINMPARTVLFTNARKFDGKDFRWISSGEYIQMSGRAGRRGMDDRGIVILMVDEKMSPTIGKQLLKGSADPLNSA
FHLTYNMVLNLLRVEEINPEYMLEKSFYQFQHYRAIPGVVEKVKNSEEQYNKIVIPNEESVVIYYKIRQQLAKLGKEIEEYIHKPKYCLP
FLQPGRLVKVKNEGDDFGWGVVVNFSKKSNVKPNSGELDPLYVVEVLLRCSKESLKNSATEAAKPAKPDEKGEMQVVPVLVHLLSAISSV
RLYIPKDLRPVDNRQSVLKSIQEVQKRFPDGIPLLDPIDDMGIQDQGLKKVIQKVEAFEHRMYSHPLHNDPNLETVYTLCEKKAQIAIDI
KSAKRELKKARTVLQMDELKCRKRVLRRLGFATSSDVIEMKGRVACEISSADELLLTEMMFNGLFNDLSAEQATALLSCFVFQENSSEMP
KLTEQLAGPLRQMQECAKRIAKVSAEAKLEIDEETYLSSFKPHLMDVVYTWATGATFAHICKMTDVFEGSIIRCMRRLEELLRQMCQAAK

--------------------------------------------------------------
>66960_66960_2_POLK-SKIV2L2_POLK_chr5_74882883_ENST00000241436_SKIV2L2_chr5_54635838_ENST00000545714_length(transcript)=4379nt_BP=1431nt
TACCTCCGGCTCTCCCGGGTGACGACGGGTAGAAAAGCAGGAGGAGCGGAGAAAGGAGAGGGCGGGGTAGGGATGCAGCTGTGCTGCATT
CTGGGAAGGGCGTTGGTCCGTCGCTCGCGCAGCCTCCTGGGAGTTGTAGTCGCGATCCTGAGGTAACGGATAAGTTTATACCATGGATAG
CACAAAGGAGAAGTGTGACAGTTACAAAGATGATCTTCTGCTTAGGATGGGACTTAATGATAATAAAGCAGGAATGGAAGGATTAGATAA
AGAGAAAATTAACAAAATTATAATGGAAGCCACGAAGGGGTCCAGATTTTATGGAAATGAGCTCAAGAAAGAAAAGCAAGTCAACCAACG
AATTGAAAATATGATGCAACAAAAAGCTCAAATCACCAGCCAACAGCTAAGAAAAGCACAATTACAGGTTGACAGATTTGCAATGGAATT
AGAACAAAGCCGAAATTTGAGCAATACCATAGTGCACATTGACATGGATGCTTTCTATGCAGCTGTAGAAATGAGGGACAATCCAGAATT
GAAGGATAAACCCATTGCTGTAGGATCAATGAGTATGCTGTCTACTTCAAATTACCATGCAAGGAGATTTGGTGTTCGTGCAGCCATGCC
AGGATTTATTGCTAAGAGGCTGTGCCCACAACTTATAATAGTGCCCCCCAACTTTGACAAATACCGAGCTGTGAGTAAAGAGGTTAAGGA
AATACTTGCTGATTATGATCCCAATTTTATGGCCATGAGTCTTGATGAAGCCTACTTGAATATAACAAAGCACTTAGAAGAAAGACAAAA
TTGGCCTGAGGATAAAAGAAGGTATTTCATCAAAATGGGAAGCTCTGTAGAAAATGATAATCCAGGAAAGGAAGTTAATAAACTGAGTGA
GCATGAACGATCCATCTCTCCACTACTTTTTGAAGAGAGTCCTTCTGATGTGCAGCCCCCAGGAGATCCTTTCCAAGTGAACTTTGAAGA
ACAAAACAATCCTCAAATACTCCAAAACTCAGTTGTTTTTGGAACATCAGCCCAGGAAGTGGTAAAGGAAATTCGTTTCAGAATTGAGCA
GAAAACAACACTGACAGCCAGTGCAGGCATTGCCCCAAATACAATGTTAGCAAAAGTATGCAGTGATAAGAATAAACCAAATGGACAATA
CCAAATTCTTCCCAATAGACAAGCTGTGATGGACTTCATCAAGGATTTACCCATTAGAAAGGTTTCTGGAATAGGAAAAGTTACAGAGAA
AATGTTAAAGGCCCTTGGAATTATTACATGTACAGAACTTTACCAACAGAGGGCATTGCTTTCTCTCCTTTTCTCTGAAACATCTTGGCA
TTATTTCCTTCATATCTCCTTGGGTCTAGGTTCAACACACCTGACGAGGGATGGAGAGAGGAAAAGTATGAGCGTTGAGAGGTATGCCAT
TGCATTGGCCTTAAGGGAAAAGCAGCGTGTAATATTTACCAGCCCAATTAAGGCTCTGAGTAACCAAAAATACCGTGAAATGTATGAAGA
ATTTCAAGATGTTGGTTTGATGACTGGTGATGTTACTATTAATCCTACGGCATCTTGTCTTGTTATGACCACAGAGATTTTGAGAAGTAT
GCTTTACAGAGGTTCCGAAGTTATGAGAGAAGTTGCTTGGGTTATATTTGATGAAATTCATTATATGAGAGATTCAGAACGTGGTGTAGT
ATGGGAAGAAACTATTATTTTGCTTCCTGATAACGTCCACTATGTCTTTCTTTCGGCTACTATTCCAAATGCCCGACAGTTTGCTGAATG
GATTTGCCATTTACATAAACAGCCTTGTCATGTTATTTACACAGATTATCGGCCCACTCCATTGCAACACTACATTTTTCCAGCAGGGGG
AGATGGCCTGCATCTTGTGGTTGATGAAAATGGTGACTTCAGAGAAGATAATTTTAATACTGCAATGCAAGTGCTTCGAGATGCAGGTGA
TTTGGCCAAAGGAGACCAGAAAGGGCGGAAAGGAGGAACAAAAGGACCATCAAATGTTTTCAAAATTGTGAAGATGATTATGGAAAGAAA
TTTCCAACCTGTGATTATTTTCAGTTTTAGTAAGAAAGATTGTGAAGCCTATGCACTTCAAATGACCAAATTAGATTTCAACACAGATGA
AGAAAAGAAGATGGTTGAAGAAGTATTCAGTAATGCAATTGATTGCTTATCCGATGAAGATAAAAAACTCCCTCAGGTAGAACATGTACT
TCCTCTTTTGAAGAGGGGAATTGGTATTCACCATGGTGGTTTACTTCCTATTTTGAAAGAAACTATAGAAATTCTCTTTTCTGAAGGATT
GATAAAGGCCTTATTTGCCACGGAGACCTTTGCTATGGGAATTAACATGCCAGCTAGAACTGTTTTATTTACAAATGCCCGCAAATTTGA
TGGGAAGGATTTCCGATGGATTTCTTCTGGTGAATACATTCAGATGTCTGGTCGTGCTGGAAGGAGAGGAATGGATGATAGAGGAATTGT
AATTCTTATGGTAGATGAAAAGATGAGCCCAACAATTGGAAAACAATTACTTAAGGGCTCCGCTGATCCTCTAAATAGTGCTTTCCATTT
GACCTACAACATGGTTTTGAACTTACTACGTGTAGAAGAAATTAATCCTGAGTACATGTTGGAAAAATCCTTCTACCAGTTTCAGCATTA
TAGAGCAATTCCAGGAGTAGTAGAGAAGGTAAAGAATTCAGAAGAACAGTATAATAAAATAGTAATTCCCAATGAAGAAAGTGTGGTTAT
CTATTATAAGATTAGACAGCAGCTTGCCAAATTGGGTAAAGAAATTGAAGAATATATTCACAAACCAAAATACTGCTTACCTTTTCTACA
ACCAGGTCGTTTGGTAAAGGTAAAGAATGAAGGAGATGACTTTGGCTGGGGAGTAGTGGTGAATTTCTCAAAAAAGTCAAATGTTAAGCC
TAACTCTGGTGAACTGGATCCTTTGTATGTAGTAGAAGTACTTCTGCGCTGTAGCAAAGAGAGCTTGAAAAATTCAGCTACAGAAGCTGC
AAAACCAGCTAAACCTGATGAGAAAGGAGAGATGCAGGTTGTCCCAGTTTTGGTGCATCTCCTGTCTGCTATCAGCAGTGTTAGGCTTTA
CATTCCTAAAGACCTTCGGCCGGTGGACAATAGACAGAGTGTTTTAAAATCAATACAGGAAGTTCAGAAACGTTTTCCTGACGGCATCCC
CTTATTAGACCCTATTGATGATATGGGCATTCAAGATCAAGGGCTGAAAAAAGTCATTCAGAAAGTAGAAGCTTTTGAGCATCGAATGTA
TTCTCATCCACTTCACAATGATCCAAATTTGGAAACTGTGTATACGCTTTGTGAAAAAAAAGCACAGATTGCAATAGATATTAAATCTGC
AAAGCGAGAACTGAAGAAAGCAAGAACAGTCCTACAAATGGATGAACTCAAATGTCGCAAACGTGTTTTAAGAAGGTTGGGATTTGCTAC
TTCTTCTGATGTAATAGAGATGAAAGGACGAGTGGCTTGTGAGATAAGCAGTGCTGATGAGCTCCTTCTAACTGAGATGATGTTTAATGG
CCTTTTCAATGACCTTTCTGCAGAACAGGCAACAGCATTATTAAGCTGCTTTGTGTTTCAAGAGAATTCTAGTGAGATGCCCAAATTAAC
AGAACAATTAGCAGGACCACTTCGTCAAATGCAGGAATGTGCTAAAAGAATTGCAAAAGTTTCAGCAGAAGCCAAATTGGAAATTGATGA
GGAAACTTATCTAAGCTCATTTAAACCTCACTTAATGGATGTAGTATATACCTGGGCAACTGGAGCTACATTTGCCCATATCTGCAAAAT
GACAGATGTCTTTGAAGGCAGCATAATTCGTTGTATGAGGCGCCTGGAAGAATTGCTTCGACAAATGTGTCAAGCAGCAAAAGCCATTGG
AAACACTGAGCTGGAAAATAAATTTGCAGAAGGAATCACCAAAATCAAGAGAGATATTGTGTTTGCTGCCAGCCTCTACTTGTAGAGTCA
GCTAAAGGAATGTGAGATTTTAAATTATTGACCACCTGTTTGATTACAGTTGACTACAAATGCCTGCAAGTGTGGATTTGGTTCTCCCAT
ACATTTTAATATGTATTATATTTAAATCAAACATCATTCATAGAAAGCATATTACATACATGTTTATACATAAGCATTACATTTTTTTAA
TAAAAATGTATACAGGTGGGGCACTGTTTTGGTGGAAGGCTTGGAGTTTTTTTAATGAGTTTAGAGCTATTAGATAACCACTGAGTTAAA

>66960_66960_2_POLK-SKIV2L2_POLK_chr5_74882883_ENST00000241436_SKIV2L2_chr5_54635838_ENST00000545714_length(amino acids)=1290AA_BP=419
MDSTKEKCDSYKDDLLLRMGLNDNKAGMEGLDKEKINKIIMEATKGSRFYGNELKKEKQVNQRIENMMQQKAQITSQQLRKAQLQVDRFA
MELEQSRNLSNTIVHIDMDAFYAAVEMRDNPELKDKPIAVGSMSMLSTSNYHARRFGVRAAMPGFIAKRLCPQLIIVPPNFDKYRAVSKE
VKEILADYDPNFMAMSLDEAYLNITKHLEERQNWPEDKRRYFIKMGSSVENDNPGKEVNKLSEHERSISPLLFEESPSDVQPPGDPFQVN
FEEQNNPQILQNSVVFGTSAQEVVKEIRFRIEQKTTLTASAGIAPNTMLAKVCSDKNKPNGQYQILPNRQAVMDFIKDLPIRKVSGIGKV
TEKMLKALGIITCTELYQQRALLSLLFSETSWHYFLHISLGLGSTHLTRDGERKSMSVERYAIALALREKQRVIFTSPIKALSNQKYREM
YEEFQDVGLMTGDVTINPTASCLVMTTEILRSMLYRGSEVMREVAWVIFDEIHYMRDSERGVVWEETIILLPDNVHYVFLSATIPNARQF
AEWICHLHKQPCHVIYTDYRPTPLQHYIFPAGGDGLHLVVDENGDFREDNFNTAMQVLRDAGDLAKGDQKGRKGGTKGPSNVFKIVKMIM
ERNFQPVIIFSFSKKDCEAYALQMTKLDFNTDEEKKMVEEVFSNAIDCLSDEDKKLPQVEHVLPLLKRGIGIHHGGLLPILKETIEILFS
EGLIKALFATETFAMGINMPARTVLFTNARKFDGKDFRWISSGEYIQMSGRAGRRGMDDRGIVILMVDEKMSPTIGKQLLKGSADPLNSA
FHLTYNMVLNLLRVEEINPEYMLEKSFYQFQHYRAIPGVVEKVKNSEEQYNKIVIPNEESVVIYYKIRQQLAKLGKEIEEYIHKPKYCLP
FLQPGRLVKVKNEGDDFGWGVVVNFSKKSNVKPNSGELDPLYVVEVLLRCSKESLKNSATEAAKPAKPDEKGEMQVVPVLVHLLSAISSV
RLYIPKDLRPVDNRQSVLKSIQEVQKRFPDGIPLLDPIDDMGIQDQGLKKVIQKVEAFEHRMYSHPLHNDPNLETVYTLCEKKAQIAIDI
KSAKRELKKARTVLQMDELKCRKRVLRRLGFATSSDVIEMKGRVACEISSADELLLTEMMFNGLFNDLSAEQATALLSCFVFQENSSEMP
KLTEQLAGPLRQMQECAKRIAKVSAEAKLEIDEETYLSSFKPHLMDVVYTWATGATFAHICKMTDVFEGSIIRCMRRLEELLRQMCQAAK

--------------------------------------------------------------
>66960_66960_3_POLK-SKIV2L2_POLK_chr5_74882883_ENST00000380481_SKIV2L2_chr5_54635838_ENST00000230640_length(transcript)=4796nt_BP=1373nt
ATGGATAGCACAAAGGAGAAGTGTGACAGTTACAAAGATGATCTTCTGCTTAGGATGGGACTTAATGATAATAAAGCAGGAATGGAAGGA
TTAGATAAAGAGAAAATTAACAAAATTATAATGGAAGCCACGAAGGGGTCCAGATTTTATGGAAATGAGCTCAAGAAAGAAAAGCAAGTC
AACCAACGAATTGAAAATATGATGCAACAAAAAGCTCAAATCACCAGCCAACAGCTAAGAAAAGCACAATTACAGATTAACATCAAATTT
TAACATTATAAAAGCAATTCTACAGAGGAACATTTACATTATGCTACAGTATCTTCAGTTGTACCTTCCTGTTCAGCATAAACATCATAT
GCCAAAGAGGTTGACAGATTTGCAATGGAATTAGAACAAAGCCGAAATTTGAGCAATACCATAGTGCACATTGACATGGATGCTTTCTAT
GCAGCTGTAGAAATGAGGGACAATCCAGAATTGAAGGATAAACCCATTGCTGTAGGATCAATGAGTATGCTGTCTACTTCAAATTACCAT
GCAAGGAGATTTGGTGTTCGTGCAGCCATGCCAGGATTTATTGCTAAGAGGCTGTGCCCACAACTTATAATAGTGCCCCCCAACTTTGAC
AAATACCGAGCTGTGAGTAAAGAGGTTAAGGAAATACTTGCTGATTATGATCCCAATTTTATGGCCATGAGTCTTGATGAAGCCTACTTG
AATATAACAAAGCACTTAGAAGAAAGACAAAATTGGCCTGAGGATAAAAGAAGGTATTTCATCAAAATGGGAAGCTCTGTAGAAAATGAT
AATCCAGGAAAGGAAGTTAATAAACTGAGTGAGCATGAACGATCCATCTCTCCACTACTTTTTGAAGAGAGTCCTTCTGATGTGCAGCCC
CCAGGAGATCCTTTCCAAGTGAACTTTGAAGAACAAAACAATCCTCAAATACTCCAAAACTCAGTTGTTTTTGGAACATCAGCCCAGGAA
GTGGTAAAGGAAATTCGTTTCAGAATTGAGCAGAAAACAACACTGACAGCCAGTGCAGGCATTGCCCCAAATACAATGTTAGCAAAAGTA
TGCAGTGATAAGAATAAACCAAATGGACAATACCAAATTCTTCCCAATAGACAAGCTGTGATGGACTTCATCAAGGATTTACCCATTAGA
AAGGTTTCTGGAATAGGAAAAGTTACAGAGAAAATGTTAAAGGCCCTTGGAATTATTACATGTACAGAACTTTACCAACAGAGGGCATTG
CTTTCTCTCCTTTTCTCTGAAACATCTTGGCATTATTTCCTTCATATCTCCTTGGGTCTAGGTTCAACACACCTGACGAGGGATGGAGAG
AGGAAAAGTATGAGCGTTGAGAGGTATGCCATTGCATTGGCCTTAAGGGAAAAGCAGCGTGTAATATTTACCAGCCCAATTAAGGCTCTG
AGTAACCAAAAATACCGTGAAATGTATGAAGAATTTCAAGATGTTGGTTTGATGACTGGTGATGTTACTATTAATCCTACGGCATCTTGT
CTTGTTATGACCACAGAGATTTTGAGAAGTATGCTTTACAGAGGTTCCGAAGTTATGAGAGAAGTTGCTTGGGTTATATTTGATGAAATT
CATTATATGAGAGATTCAGAACGTGGTGTAGTATGGGAAGAAACTATTATTTTGCTTCCTGATAACGTCCACTATGTCTTTCTTTCGGCT
ACTATTCCAAATGCCCGACAGTTTGCTGAATGGATTTGCCATTTACATAAACAGCCTTGTCATGTTATTTACACAGATTATCGGCCCACT
CCATTGCAACACTACATTTTTCCAGCAGGGGGAGATGGCCTGCATCTTGTGGTTGATGAAAATGGTGACTTCAGAGAAGATAATTTTAAT
ACTGCAATGCAAGTGCTTCGAGATGCAGGTGATTTGGCCAAAGGAGACCAGAAAGGGCGGAAAGGAGGAACAAAAGGACCATCAAATGTT
TTCAAAATTGTGAAGATGATTATGGAAAGAAATTTCCAACCTGTGATTATTTTCAGTTTTAGTAAGAAAGATTGTGAAGCCTATGCACTT
CAAATGACCAAATTAGATTTCAACACAGATGAAGAAAAGAAGATGGTTGAAGAAGTATTCAGTAATGCAATTGATTGCTTATCCGATGAA
GATAAAAAACTCCCTCAGGTAGAACATGTACTTCCTCTTTTGAAGAGGGGAATTGGTATTCACCATGGTGGTTTACTTCCTATTTTGAAA
GAAACTATAGAAATTCTCTTTTCTGAAGGATTGATAAAGGCCTTATTTGCCACGGAGACCTTTGCTATGGGAATTAACATGCCAGCTAGA
ACTGTTTTATTTACAAATGCCCGCAAATTTGATGGGAAGGATTTCCGATGGATTTCTTCTGGTGAATACATTCAGATGTCTGGTCGTGCT
GGAAGGAGAGGAATGGATGATAGAGGAATTGTAATTCTTATGGTAGATGAAAAGATGAGCCCAACAATTGGAAAACAATTACTTAAGGGC
TCCGCTGATCCTCTAAATAGTGCTTTCCATTTGACCTACAACATGGTTTTGAACTTACTACGTGTAGAAGAAATTAATCCTGAGTACATG
TTGGAAAAATCCTTCTACCAGTTTCAGCATTATAGAGCAATTCCAGGAGTAGTAGAGAAGGTAAAGAATTCAGAAGAACAGTATAATAAA
ATAGTAATTCCCAATGAAGAAAGTGTGGTTATCTATTATAAGATTAGACAGCAGCTTGCCAAATTGGGTAAAGAAATTGAAGAATATATT
CACAAACCAAAATACTGCTTACCTTTTCTACAACCAGGTCGTTTGGTAAAGGTAAAGAATGAAGGAGATGACTTTGGCTGGGGAGTAGTG
GTGAATTTCTCAAAAAAGTCAAATGTTAAGCCTAACTCTGGTGAACTGGATCCTTTGTATGTAGTAGAAGTACTTCTGCGCTGTAGCAAA
GAGAGCTTGAAAAATTCAGCTACAGAAGCTGCAAAACCAGCTAAACCTGATGAGAAAGGAGAGATGCAGGTTGTCCCAGTTTTGGTGCAT
CTCCTGTCTGCTATCAGCAGTGTTAGGCTTTACATTCCTAAAGACCTTCGGCCGGTGGACAATAGACAGAGTGTTTTAAAATCAATACAG
GAAGTTCAGAAACGTTTTCCTGACGGCATCCCCTTATTAGACCCTATTGATGATATGGGCATTCAAGATCAAGGGCTGAAAAAAGTCATT
CAGAAAGTAGAAGCTTTTGAGCATCGAATGTATTCTCATCCACTTCACAATGATCCAAATTTGGAAACTGTGTATACGCTTTGTGAAAAA
AAAGCACAGATTGCAATAGATATTAAATCTGCAAAGCGAGAACTGAAGAAAGCAAGAACAGTCCTACAAATGGATGAACTCAAATGTCGC
AAACGTGTTTTAAGAAGGTTGGGATTTGCTACTTCTTCTGATGTAATAGAGATGAAAGGACGAGTGGCTTGTGAGATAAGCAGTGCTGAT
GAGCTCCTTCTAACTGAGATGATGTTTAATGGCCTTTTCAATGACCTTTCTGCAGAACAGGCAACAGCATTATTAAGCTGCTTTGTGTTT
CAAGAGAATTCTAGTGAGATGCCCAAATTAACAGAACAATTAGCAGGACCACTTCGTCAAATGCAGGAATGTGCTAAAAGAATTGCAAAA
GTTTCAGCAGAAGCCAAATTGGAAATTGATGAGGAAACTTATCTAAGCTCATTTAAACCTCACTTAATGGATGTAGTATATACCTGGGCA
ACTGGAGCTACATTTGCCCATATCTGCAAAATGACAGATGTCTTTGAAGGCAGCATAATTCGTTGTATGAGGCGCCTGGAAGAATTGCTT
CGACAAATGTGTCAAGCAGCAAAAGCCATTGGAAACACTGAGCTGGAAAATAAATTTGCAGAAGGAATCACCAAAATCAAGAGAGATATT
GTGTTTGCTGCCAGCCTCTACTTGTAGAGTCAGCTAAAGGAATGTGAGATTTTAAATTATTGACCACCTGTTTGATTACAGTTGACTACA
AATGCCTGCAAGTGTGGATTTGGTTCTCCCATACATTTTAATATGTATTATATTTAAATCAAACATCATTCATAGAAAGCATATTACATA
CATGTTTATACATAAGCATTACATTTTTTTAATAAAAATGTATACAGGTGGGGCACTGTTTTGGTGGAAGGCTTGGAGTTTTTTTAATGA
GTTTAGAGCTATTAGATAACCACTGAGTTAAAGGTAACTATGTACACACAAAGTGTGCATCCAAGAGGCATAGCAGCAGCAGAAGTCTTT
AAAGGCTTGTACACCAGGAAGAAAGATGCATCCTCTTGCCTTGTGGCAATCATTTTCCTTTAGAAAACAGGCCAGCTTCACCTGGGCACC
CTGCTGCCTTTCAAGGCTGGTGATTGCTCGGATAGTGATTCCCAGTTGTTGGTGTTTCATGCAGAGTTGTATGAGAGTCCTCCTCTTTTC
TTTCTTTAAAAGAAGTTCTTTCTTTGAAGAAATCCGATACATATACAGCCTACAGTGCAAAATATTTAATGGTATAATTTAGATCAAGTT
AAAAACTACATACAAAGTTGTGATCAACAGCATCCTAAGATAAATATAAACAAAAGGATATACTTTGAGGTGTACAGATTAAGCATATAA
AAAATTAGAGACTAACTGGGATTTTTTAAAGATTATTCCAAATTAAGAGTTGCTTTGTTATGCCTTCAGCAAATAGCTTCATTTTGCCAA

>66960_66960_3_POLK-SKIV2L2_POLK_chr5_74882883_ENST00000380481_SKIV2L2_chr5_54635838_ENST00000230640_length(amino acids)=1200AA_BP=329
MELEQSRNLSNTIVHIDMDAFYAAVEMRDNPELKDKPIAVGSMSMLSTSNYHARRFGVRAAMPGFIAKRLCPQLIIVPPNFDKYRAVSKE
VKEILADYDPNFMAMSLDEAYLNITKHLEERQNWPEDKRRYFIKMGSSVENDNPGKEVNKLSEHERSISPLLFEESPSDVQPPGDPFQVN
FEEQNNPQILQNSVVFGTSAQEVVKEIRFRIEQKTTLTASAGIAPNTMLAKVCSDKNKPNGQYQILPNRQAVMDFIKDLPIRKVSGIGKV
TEKMLKALGIITCTELYQQRALLSLLFSETSWHYFLHISLGLGSTHLTRDGERKSMSVERYAIALALREKQRVIFTSPIKALSNQKYREM
YEEFQDVGLMTGDVTINPTASCLVMTTEILRSMLYRGSEVMREVAWVIFDEIHYMRDSERGVVWEETIILLPDNVHYVFLSATIPNARQF
AEWICHLHKQPCHVIYTDYRPTPLQHYIFPAGGDGLHLVVDENGDFREDNFNTAMQVLRDAGDLAKGDQKGRKGGTKGPSNVFKIVKMIM
ERNFQPVIIFSFSKKDCEAYALQMTKLDFNTDEEKKMVEEVFSNAIDCLSDEDKKLPQVEHVLPLLKRGIGIHHGGLLPILKETIEILFS
EGLIKALFATETFAMGINMPARTVLFTNARKFDGKDFRWISSGEYIQMSGRAGRRGMDDRGIVILMVDEKMSPTIGKQLLKGSADPLNSA
FHLTYNMVLNLLRVEEINPEYMLEKSFYQFQHYRAIPGVVEKVKNSEEQYNKIVIPNEESVVIYYKIRQQLAKLGKEIEEYIHKPKYCLP
FLQPGRLVKVKNEGDDFGWGVVVNFSKKSNVKPNSGELDPLYVVEVLLRCSKESLKNSATEAAKPAKPDEKGEMQVVPVLVHLLSAISSV
RLYIPKDLRPVDNRQSVLKSIQEVQKRFPDGIPLLDPIDDMGIQDQGLKKVIQKVEAFEHRMYSHPLHNDPNLETVYTLCEKKAQIAIDI
KSAKRELKKARTVLQMDELKCRKRVLRRLGFATSSDVIEMKGRVACEISSADELLLTEMMFNGLFNDLSAEQATALLSCFVFQENSSEMP
KLTEQLAGPLRQMQECAKRIAKVSAEAKLEIDEETYLSSFKPHLMDVVYTWATGATFAHICKMTDVFEGSIIRCMRRLEELLRQMCQAAK

--------------------------------------------------------------
>66960_66960_4_POLK-SKIV2L2_POLK_chr5_74882883_ENST00000380481_SKIV2L2_chr5_54635838_ENST00000545714_length(transcript)=4321nt_BP=1373nt
ATGGATAGCACAAAGGAGAAGTGTGACAGTTACAAAGATGATCTTCTGCTTAGGATGGGACTTAATGATAATAAAGCAGGAATGGAAGGA
TTAGATAAAGAGAAAATTAACAAAATTATAATGGAAGCCACGAAGGGGTCCAGATTTTATGGAAATGAGCTCAAGAAAGAAAAGCAAGTC
AACCAACGAATTGAAAATATGATGCAACAAAAAGCTCAAATCACCAGCCAACAGCTAAGAAAAGCACAATTACAGATTAACATCAAATTT
TAACATTATAAAAGCAATTCTACAGAGGAACATTTACATTATGCTACAGTATCTTCAGTTGTACCTTCCTGTTCAGCATAAACATCATAT
GCCAAAGAGGTTGACAGATTTGCAATGGAATTAGAACAAAGCCGAAATTTGAGCAATACCATAGTGCACATTGACATGGATGCTTTCTAT
GCAGCTGTAGAAATGAGGGACAATCCAGAATTGAAGGATAAACCCATTGCTGTAGGATCAATGAGTATGCTGTCTACTTCAAATTACCAT
GCAAGGAGATTTGGTGTTCGTGCAGCCATGCCAGGATTTATTGCTAAGAGGCTGTGCCCACAACTTATAATAGTGCCCCCCAACTTTGAC
AAATACCGAGCTGTGAGTAAAGAGGTTAAGGAAATACTTGCTGATTATGATCCCAATTTTATGGCCATGAGTCTTGATGAAGCCTACTTG
AATATAACAAAGCACTTAGAAGAAAGACAAAATTGGCCTGAGGATAAAAGAAGGTATTTCATCAAAATGGGAAGCTCTGTAGAAAATGAT
AATCCAGGAAAGGAAGTTAATAAACTGAGTGAGCATGAACGATCCATCTCTCCACTACTTTTTGAAGAGAGTCCTTCTGATGTGCAGCCC
CCAGGAGATCCTTTCCAAGTGAACTTTGAAGAACAAAACAATCCTCAAATACTCCAAAACTCAGTTGTTTTTGGAACATCAGCCCAGGAA
GTGGTAAAGGAAATTCGTTTCAGAATTGAGCAGAAAACAACACTGACAGCCAGTGCAGGCATTGCCCCAAATACAATGTTAGCAAAAGTA
TGCAGTGATAAGAATAAACCAAATGGACAATACCAAATTCTTCCCAATAGACAAGCTGTGATGGACTTCATCAAGGATTTACCCATTAGA
AAGGTTTCTGGAATAGGAAAAGTTACAGAGAAAATGTTAAAGGCCCTTGGAATTATTACATGTACAGAACTTTACCAACAGAGGGCATTG
CTTTCTCTCCTTTTCTCTGAAACATCTTGGCATTATTTCCTTCATATCTCCTTGGGTCTAGGTTCAACACACCTGACGAGGGATGGAGAG
AGGAAAAGTATGAGCGTTGAGAGGTATGCCATTGCATTGGCCTTAAGGGAAAAGCAGCGTGTAATATTTACCAGCCCAATTAAGGCTCTG
AGTAACCAAAAATACCGTGAAATGTATGAAGAATTTCAAGATGTTGGTTTGATGACTGGTGATGTTACTATTAATCCTACGGCATCTTGT
CTTGTTATGACCACAGAGATTTTGAGAAGTATGCTTTACAGAGGTTCCGAAGTTATGAGAGAAGTTGCTTGGGTTATATTTGATGAAATT
CATTATATGAGAGATTCAGAACGTGGTGTAGTATGGGAAGAAACTATTATTTTGCTTCCTGATAACGTCCACTATGTCTTTCTTTCGGCT
ACTATTCCAAATGCCCGACAGTTTGCTGAATGGATTTGCCATTTACATAAACAGCCTTGTCATGTTATTTACACAGATTATCGGCCCACT
CCATTGCAACACTACATTTTTCCAGCAGGGGGAGATGGCCTGCATCTTGTGGTTGATGAAAATGGTGACTTCAGAGAAGATAATTTTAAT
ACTGCAATGCAAGTGCTTCGAGATGCAGGTGATTTGGCCAAAGGAGACCAGAAAGGGCGGAAAGGAGGAACAAAAGGACCATCAAATGTT
TTCAAAATTGTGAAGATGATTATGGAAAGAAATTTCCAACCTGTGATTATTTTCAGTTTTAGTAAGAAAGATTGTGAAGCCTATGCACTT
CAAATGACCAAATTAGATTTCAACACAGATGAAGAAAAGAAGATGGTTGAAGAAGTATTCAGTAATGCAATTGATTGCTTATCCGATGAA
GATAAAAAACTCCCTCAGGTAGAACATGTACTTCCTCTTTTGAAGAGGGGAATTGGTATTCACCATGGTGGTTTACTTCCTATTTTGAAA
GAAACTATAGAAATTCTCTTTTCTGAAGGATTGATAAAGGCCTTATTTGCCACGGAGACCTTTGCTATGGGAATTAACATGCCAGCTAGA
ACTGTTTTATTTACAAATGCCCGCAAATTTGATGGGAAGGATTTCCGATGGATTTCTTCTGGTGAATACATTCAGATGTCTGGTCGTGCT
GGAAGGAGAGGAATGGATGATAGAGGAATTGTAATTCTTATGGTAGATGAAAAGATGAGCCCAACAATTGGAAAACAATTACTTAAGGGC
TCCGCTGATCCTCTAAATAGTGCTTTCCATTTGACCTACAACATGGTTTTGAACTTACTACGTGTAGAAGAAATTAATCCTGAGTACATG
TTGGAAAAATCCTTCTACCAGTTTCAGCATTATAGAGCAATTCCAGGAGTAGTAGAGAAGGTAAAGAATTCAGAAGAACAGTATAATAAA
ATAGTAATTCCCAATGAAGAAAGTGTGGTTATCTATTATAAGATTAGACAGCAGCTTGCCAAATTGGGTAAAGAAATTGAAGAATATATT
CACAAACCAAAATACTGCTTACCTTTTCTACAACCAGGTCGTTTGGTAAAGGTAAAGAATGAAGGAGATGACTTTGGCTGGGGAGTAGTG
GTGAATTTCTCAAAAAAGTCAAATGTTAAGCCTAACTCTGGTGAACTGGATCCTTTGTATGTAGTAGAAGTACTTCTGCGCTGTAGCAAA
GAGAGCTTGAAAAATTCAGCTACAGAAGCTGCAAAACCAGCTAAACCTGATGAGAAAGGAGAGATGCAGGTTGTCCCAGTTTTGGTGCAT
CTCCTGTCTGCTATCAGCAGTGTTAGGCTTTACATTCCTAAAGACCTTCGGCCGGTGGACAATAGACAGAGTGTTTTAAAATCAATACAG
GAAGTTCAGAAACGTTTTCCTGACGGCATCCCCTTATTAGACCCTATTGATGATATGGGCATTCAAGATCAAGGGCTGAAAAAAGTCATT
CAGAAAGTAGAAGCTTTTGAGCATCGAATGTATTCTCATCCACTTCACAATGATCCAAATTTGGAAACTGTGTATACGCTTTGTGAAAAA
AAAGCACAGATTGCAATAGATATTAAATCTGCAAAGCGAGAACTGAAGAAAGCAAGAACAGTCCTACAAATGGATGAACTCAAATGTCGC
AAACGTGTTTTAAGAAGGTTGGGATTTGCTACTTCTTCTGATGTAATAGAGATGAAAGGACGAGTGGCTTGTGAGATAAGCAGTGCTGAT
GAGCTCCTTCTAACTGAGATGATGTTTAATGGCCTTTTCAATGACCTTTCTGCAGAACAGGCAACAGCATTATTAAGCTGCTTTGTGTTT
CAAGAGAATTCTAGTGAGATGCCCAAATTAACAGAACAATTAGCAGGACCACTTCGTCAAATGCAGGAATGTGCTAAAAGAATTGCAAAA
GTTTCAGCAGAAGCCAAATTGGAAATTGATGAGGAAACTTATCTAAGCTCATTTAAACCTCACTTAATGGATGTAGTATATACCTGGGCA
ACTGGAGCTACATTTGCCCATATCTGCAAAATGACAGATGTCTTTGAAGGCAGCATAATTCGTTGTATGAGGCGCCTGGAAGAATTGCTT
CGACAAATGTGTCAAGCAGCAAAAGCCATTGGAAACACTGAGCTGGAAAATAAATTTGCAGAAGGAATCACCAAAATCAAGAGAGATATT
GTGTTTGCTGCCAGCCTCTACTTGTAGAGTCAGCTAAAGGAATGTGAGATTTTAAATTATTGACCACCTGTTTGATTACAGTTGACTACA
AATGCCTGCAAGTGTGGATTTGGTTCTCCCATACATTTTAATATGTATTATATTTAAATCAAACATCATTCATAGAAAGCATATTACATA
CATGTTTATACATAAGCATTACATTTTTTTAATAAAAATGTATACAGGTGGGGCACTGTTTTGGTGGAAGGCTTGGAGTTTTTTTAATGA
GTTTAGAGCTATTAGATAACCACTGAGTTAAAGGTAACTATGTACACACAAAGTGTGCATCCAAGAGGCATAGCAGCAGCAGAAGTCTTT

>66960_66960_4_POLK-SKIV2L2_POLK_chr5_74882883_ENST00000380481_SKIV2L2_chr5_54635838_ENST00000545714_length(amino acids)=1200AA_BP=329
MELEQSRNLSNTIVHIDMDAFYAAVEMRDNPELKDKPIAVGSMSMLSTSNYHARRFGVRAAMPGFIAKRLCPQLIIVPPNFDKYRAVSKE
VKEILADYDPNFMAMSLDEAYLNITKHLEERQNWPEDKRRYFIKMGSSVENDNPGKEVNKLSEHERSISPLLFEESPSDVQPPGDPFQVN
FEEQNNPQILQNSVVFGTSAQEVVKEIRFRIEQKTTLTASAGIAPNTMLAKVCSDKNKPNGQYQILPNRQAVMDFIKDLPIRKVSGIGKV
TEKMLKALGIITCTELYQQRALLSLLFSETSWHYFLHISLGLGSTHLTRDGERKSMSVERYAIALALREKQRVIFTSPIKALSNQKYREM
YEEFQDVGLMTGDVTINPTASCLVMTTEILRSMLYRGSEVMREVAWVIFDEIHYMRDSERGVVWEETIILLPDNVHYVFLSATIPNARQF
AEWICHLHKQPCHVIYTDYRPTPLQHYIFPAGGDGLHLVVDENGDFREDNFNTAMQVLRDAGDLAKGDQKGRKGGTKGPSNVFKIVKMIM
ERNFQPVIIFSFSKKDCEAYALQMTKLDFNTDEEKKMVEEVFSNAIDCLSDEDKKLPQVEHVLPLLKRGIGIHHGGLLPILKETIEILFS
EGLIKALFATETFAMGINMPARTVLFTNARKFDGKDFRWISSGEYIQMSGRAGRRGMDDRGIVILMVDEKMSPTIGKQLLKGSADPLNSA
FHLTYNMVLNLLRVEEINPEYMLEKSFYQFQHYRAIPGVVEKVKNSEEQYNKIVIPNEESVVIYYKIRQQLAKLGKEIEEYIHKPKYCLP
FLQPGRLVKVKNEGDDFGWGVVVNFSKKSNVKPNSGELDPLYVVEVLLRCSKESLKNSATEAAKPAKPDEKGEMQVVPVLVHLLSAISSV
RLYIPKDLRPVDNRQSVLKSIQEVQKRFPDGIPLLDPIDDMGIQDQGLKKVIQKVEAFEHRMYSHPLHNDPNLETVYTLCEKKAQIAIDI
KSAKRELKKARTVLQMDELKCRKRVLRRLGFATSSDVIEMKGRVACEISSADELLLTEMMFNGLFNDLSAEQATALLSCFVFQENSSEMP
KLTEQLAGPLRQMQECAKRIAKVSAEAKLEIDEETYLSSFKPHLMDVVYTWATGATFAHICKMTDVFEGSIIRCMRRLEELLRQMCQAAK

--------------------------------------------------------------
>66960_66960_5_POLK-SKIV2L2_POLK_chr5_74882883_ENST00000504026_SKIV2L2_chr5_54635838_ENST00000230640_length(transcript)=4682nt_BP=1259nt
ATGGATAGCACAAAGGAGAAGTGTGACAGTTACAAAGATGATCTTCTGCTTAGGATGGGACTTAATGATAATAAAGCAGGAATGGAAGGA
TTAGATAAAGAGAAAATTAACAAAATTATAATGGAAGCCACGAAGGGGTCCAGATTTTATGGAAATGAGCTCAAGAAAGAAAAGCAAGTC
AACCAACGAATTGAAAATATGATGCAACAAAAAGCTCAAATCACCAGCCAACAGCTAAGAAAAGCACAATTACAGGTTGACAGATTTGCA
ATGGAATTAGAACAAAGCCGAAATTTGAGCAATACCATAGTGCACATTGACATGGATGCTTTCTATGCAGCTGTAGAAATGAGGGACAAT
CCAGAATTGAAGGATAAACCCATTGCTGTAGGATCAATGAGTATGCTGTCTACTTCAAATTACCATGCAAGGAGATTTGGTGTTCGTGCA
GCCATGCCAGGATTTATTGCTAAGAGGCTGTGCCCACAACTTATAATAGTGCCCCCCAACTTTGACAAATACCGAGCTGTGAGTAAAGAG
GTTAAGGAAATACTTGCTGATTATGATCCCAATTTTATGGCCATGAGTCTTGATGAAGCCTACTTGAATATAACAAAGCACTTAGAAGAA
AGACAAAATTGGCCTGAGGATAAAAGAAGGTATTTCATCAAAATGGGAAGCTCTGTAGAAAATGATAATCCAGGAAAGGAAGTTAATAAA
CTGAGTGAGCATGAACGATCCATCTCTCCACTACTTTTTGAAGAGAGTCCTTCTGATGTGCAGCCCCCAGGAGATCCTTTCCAAGTGAAC
TTTGAAGAACAAAACAATCCTCAAATACTCCAAAACTCAGTTGTTTTTGGAACATCAGCCCAGGAAGTGGTAAAGGAAATTCGTTTCAGA
ATTGAGCAGAAAACAACACTGACAGCCAGTGCAGGCATTGCCCCAAATACAATGTTAGCAAAAGTATGCAGTGATAAGAATAAACCAAAT
GGACAATACCAAATTCTTCCCAATAGACAAGCTGTGATGGACTTCATCAAGGATTTACCCATTAGAAAGGTTTCTGGAATAGGAAAAGTT
ACAGAGAAAATGTTAAAGGCCCTTGGAATTATTACATGTACAGAACTTTACCAACAGAGGGCATTGCTTTCTCTCCTTTTCTCTGAAACA
TCTTGGCATTATTTCCTTCATATCTCCTTGGGTCTAGGTTCAACACACCTGACGAGGGATGGAGAGAGGAAAAGTATGAGCGTTGAGAGG
TATGCCATTGCATTGGCCTTAAGGGAAAAGCAGCGTGTAATATTTACCAGCCCAATTAAGGCTCTGAGTAACCAAAAATACCGTGAAATG
TATGAAGAATTTCAAGATGTTGGTTTGATGACTGGTGATGTTACTATTAATCCTACGGCATCTTGTCTTGTTATGACCACAGAGATTTTG
AGAAGTATGCTTTACAGAGGTTCCGAAGTTATGAGAGAAGTTGCTTGGGTTATATTTGATGAAATTCATTATATGAGAGATTCAGAACGT
GGTGTAGTATGGGAAGAAACTATTATTTTGCTTCCTGATAACGTCCACTATGTCTTTCTTTCGGCTACTATTCCAAATGCCCGACAGTTT
GCTGAATGGATTTGCCATTTACATAAACAGCCTTGTCATGTTATTTACACAGATTATCGGCCCACTCCATTGCAACACTACATTTTTCCA
GCAGGGGGAGATGGCCTGCATCTTGTGGTTGATGAAAATGGTGACTTCAGAGAAGATAATTTTAATACTGCAATGCAAGTGCTTCGAGAT
GCAGGTGATTTGGCCAAAGGAGACCAGAAAGGGCGGAAAGGAGGAACAAAAGGACCATCAAATGTTTTCAAAATTGTGAAGATGATTATG
GAAAGAAATTTCCAACCTGTGATTATTTTCAGTTTTAGTAAGAAAGATTGTGAAGCCTATGCACTTCAAATGACCAAATTAGATTTCAAC
ACAGATGAAGAAAAGAAGATGGTTGAAGAAGTATTCAGTAATGCAATTGATTGCTTATCCGATGAAGATAAAAAACTCCCTCAGGTAGAA
CATGTACTTCCTCTTTTGAAGAGGGGAATTGGTATTCACCATGGTGGTTTACTTCCTATTTTGAAAGAAACTATAGAAATTCTCTTTTCT
GAAGGATTGATAAAGGCCTTATTTGCCACGGAGACCTTTGCTATGGGAATTAACATGCCAGCTAGAACTGTTTTATTTACAAATGCCCGC
AAATTTGATGGGAAGGATTTCCGATGGATTTCTTCTGGTGAATACATTCAGATGTCTGGTCGTGCTGGAAGGAGAGGAATGGATGATAGA
GGAATTGTAATTCTTATGGTAGATGAAAAGATGAGCCCAACAATTGGAAAACAATTACTTAAGGGCTCCGCTGATCCTCTAAATAGTGCT
TTCCATTTGACCTACAACATGGTTTTGAACTTACTACGTGTAGAAGAAATTAATCCTGAGTACATGTTGGAAAAATCCTTCTACCAGTTT
CAGCATTATAGAGCAATTCCAGGAGTAGTAGAGAAGGTAAAGAATTCAGAAGAACAGTATAATAAAATAGTAATTCCCAATGAAGAAAGT
GTGGTTATCTATTATAAGATTAGACAGCAGCTTGCCAAATTGGGTAAAGAAATTGAAGAATATATTCACAAACCAAAATACTGCTTACCT
TTTCTACAACCAGGTCGTTTGGTAAAGGTAAAGAATGAAGGAGATGACTTTGGCTGGGGAGTAGTGGTGAATTTCTCAAAAAAGTCAAAT
GTTAAGCCTAACTCTGGTGAACTGGATCCTTTGTATGTAGTAGAAGTACTTCTGCGCTGTAGCAAAGAGAGCTTGAAAAATTCAGCTACA
GAAGCTGCAAAACCAGCTAAACCTGATGAGAAAGGAGAGATGCAGGTTGTCCCAGTTTTGGTGCATCTCCTGTCTGCTATCAGCAGTGTT
AGGCTTTACATTCCTAAAGACCTTCGGCCGGTGGACAATAGACAGAGTGTTTTAAAATCAATACAGGAAGTTCAGAAACGTTTTCCTGAC
GGCATCCCCTTATTAGACCCTATTGATGATATGGGCATTCAAGATCAAGGGCTGAAAAAAGTCATTCAGAAAGTAGAAGCTTTTGAGCAT
CGAATGTATTCTCATCCACTTCACAATGATCCAAATTTGGAAACTGTGTATACGCTTTGTGAAAAAAAAGCACAGATTGCAATAGATATT
AAATCTGCAAAGCGAGAACTGAAGAAAGCAAGAACAGTCCTACAAATGGATGAACTCAAATGTCGCAAACGTGTTTTAAGAAGGTTGGGA
TTTGCTACTTCTTCTGATGTAATAGAGATGAAAGGACGAGTGGCTTGTGAGATAAGCAGTGCTGATGAGCTCCTTCTAACTGAGATGATG
TTTAATGGCCTTTTCAATGACCTTTCTGCAGAACAGGCAACAGCATTATTAAGCTGCTTTGTGTTTCAAGAGAATTCTAGTGAGATGCCC
AAATTAACAGAACAATTAGCAGGACCACTTCGTCAAATGCAGGAATGTGCTAAAAGAATTGCAAAAGTTTCAGCAGAAGCCAAATTGGAA
ATTGATGAGGAAACTTATCTAAGCTCATTTAAACCTCACTTAATGGATGTAGTATATACCTGGGCAACTGGAGCTACATTTGCCCATATC
TGCAAAATGACAGATGTCTTTGAAGGCAGCATAATTCGTTGTATGAGGCGCCTGGAAGAATTGCTTCGACAAATGTGTCAAGCAGCAAAA
GCCATTGGAAACACTGAGCTGGAAAATAAATTTGCAGAAGGAATCACCAAAATCAAGAGAGATATTGTGTTTGCTGCCAGCCTCTACTTG
TAGAGTCAGCTAAAGGAATGTGAGATTTTAAATTATTGACCACCTGTTTGATTACAGTTGACTACAAATGCCTGCAAGTGTGGATTTGGT
TCTCCCATACATTTTAATATGTATTATATTTAAATCAAACATCATTCATAGAAAGCATATTACATACATGTTTATACATAAGCATTACAT
TTTTTTAATAAAAATGTATACAGGTGGGGCACTGTTTTGGTGGAAGGCTTGGAGTTTTTTTAATGAGTTTAGAGCTATTAGATAACCACT
GAGTTAAAGGTAACTATGTACACACAAAGTGTGCATCCAAGAGGCATAGCAGCAGCAGAAGTCTTTAAAGGCTTGTACACCAGGAAGAAA
GATGCATCCTCTTGCCTTGTGGCAATCATTTTCCTTTAGAAAACAGGCCAGCTTCACCTGGGCACCCTGCTGCCTTTCAAGGCTGGTGAT
TGCTCGGATAGTGATTCCCAGTTGTTGGTGTTTCATGCAGAGTTGTATGAGAGTCCTCCTCTTTTCTTTCTTTAAAAGAAGTTCTTTCTT
TGAAGAAATCCGATACATATACAGCCTACAGTGCAAAATATTTAATGGTATAATTTAGATCAAGTTAAAAACTACATACAAAGTTGTGAT
CAACAGCATCCTAAGATAAATATAAACAAAAGGATATACTTTGAGGTGTACAGATTAAGCATATAAAAAATTAGAGACTAACTGGGATTT
TTTAAAGATTATTCCAAATTAAGAGTTGCTTTGTTATGCCTTCAGCAAATAGCTTCATTTTGCCAATACTGAATAAAAGAGTTATTTCTA

>66960_66960_5_POLK-SKIV2L2_POLK_chr5_74882883_ENST00000504026_SKIV2L2_chr5_54635838_ENST00000230640_length(amino acids)=1290AA_BP=419
MDSTKEKCDSYKDDLLLRMGLNDNKAGMEGLDKEKINKIIMEATKGSRFYGNELKKEKQVNQRIENMMQQKAQITSQQLRKAQLQVDRFA
MELEQSRNLSNTIVHIDMDAFYAAVEMRDNPELKDKPIAVGSMSMLSTSNYHARRFGVRAAMPGFIAKRLCPQLIIVPPNFDKYRAVSKE
VKEILADYDPNFMAMSLDEAYLNITKHLEERQNWPEDKRRYFIKMGSSVENDNPGKEVNKLSEHERSISPLLFEESPSDVQPPGDPFQVN
FEEQNNPQILQNSVVFGTSAQEVVKEIRFRIEQKTTLTASAGIAPNTMLAKVCSDKNKPNGQYQILPNRQAVMDFIKDLPIRKVSGIGKV
TEKMLKALGIITCTELYQQRALLSLLFSETSWHYFLHISLGLGSTHLTRDGERKSMSVERYAIALALREKQRVIFTSPIKALSNQKYREM
YEEFQDVGLMTGDVTINPTASCLVMTTEILRSMLYRGSEVMREVAWVIFDEIHYMRDSERGVVWEETIILLPDNVHYVFLSATIPNARQF
AEWICHLHKQPCHVIYTDYRPTPLQHYIFPAGGDGLHLVVDENGDFREDNFNTAMQVLRDAGDLAKGDQKGRKGGTKGPSNVFKIVKMIM
ERNFQPVIIFSFSKKDCEAYALQMTKLDFNTDEEKKMVEEVFSNAIDCLSDEDKKLPQVEHVLPLLKRGIGIHHGGLLPILKETIEILFS
EGLIKALFATETFAMGINMPARTVLFTNARKFDGKDFRWISSGEYIQMSGRAGRRGMDDRGIVILMVDEKMSPTIGKQLLKGSADPLNSA
FHLTYNMVLNLLRVEEINPEYMLEKSFYQFQHYRAIPGVVEKVKNSEEQYNKIVIPNEESVVIYYKIRQQLAKLGKEIEEYIHKPKYCLP
FLQPGRLVKVKNEGDDFGWGVVVNFSKKSNVKPNSGELDPLYVVEVLLRCSKESLKNSATEAAKPAKPDEKGEMQVVPVLVHLLSAISSV
RLYIPKDLRPVDNRQSVLKSIQEVQKRFPDGIPLLDPIDDMGIQDQGLKKVIQKVEAFEHRMYSHPLHNDPNLETVYTLCEKKAQIAIDI
KSAKRELKKARTVLQMDELKCRKRVLRRLGFATSSDVIEMKGRVACEISSADELLLTEMMFNGLFNDLSAEQATALLSCFVFQENSSEMP
KLTEQLAGPLRQMQECAKRIAKVSAEAKLEIDEETYLSSFKPHLMDVVYTWATGATFAHICKMTDVFEGSIIRCMRRLEELLRQMCQAAK

--------------------------------------------------------------
>66960_66960_6_POLK-SKIV2L2_POLK_chr5_74882883_ENST00000504026_SKIV2L2_chr5_54635838_ENST00000545714_length(transcript)=4207nt_BP=1259nt
ATGGATAGCACAAAGGAGAAGTGTGACAGTTACAAAGATGATCTTCTGCTTAGGATGGGACTTAATGATAATAAAGCAGGAATGGAAGGA
TTAGATAAAGAGAAAATTAACAAAATTATAATGGAAGCCACGAAGGGGTCCAGATTTTATGGAAATGAGCTCAAGAAAGAAAAGCAAGTC
AACCAACGAATTGAAAATATGATGCAACAAAAAGCTCAAATCACCAGCCAACAGCTAAGAAAAGCACAATTACAGGTTGACAGATTTGCA
ATGGAATTAGAACAAAGCCGAAATTTGAGCAATACCATAGTGCACATTGACATGGATGCTTTCTATGCAGCTGTAGAAATGAGGGACAAT
CCAGAATTGAAGGATAAACCCATTGCTGTAGGATCAATGAGTATGCTGTCTACTTCAAATTACCATGCAAGGAGATTTGGTGTTCGTGCA
GCCATGCCAGGATTTATTGCTAAGAGGCTGTGCCCACAACTTATAATAGTGCCCCCCAACTTTGACAAATACCGAGCTGTGAGTAAAGAG
GTTAAGGAAATACTTGCTGATTATGATCCCAATTTTATGGCCATGAGTCTTGATGAAGCCTACTTGAATATAACAAAGCACTTAGAAGAA
AGACAAAATTGGCCTGAGGATAAAAGAAGGTATTTCATCAAAATGGGAAGCTCTGTAGAAAATGATAATCCAGGAAAGGAAGTTAATAAA
CTGAGTGAGCATGAACGATCCATCTCTCCACTACTTTTTGAAGAGAGTCCTTCTGATGTGCAGCCCCCAGGAGATCCTTTCCAAGTGAAC
TTTGAAGAACAAAACAATCCTCAAATACTCCAAAACTCAGTTGTTTTTGGAACATCAGCCCAGGAAGTGGTAAAGGAAATTCGTTTCAGA
ATTGAGCAGAAAACAACACTGACAGCCAGTGCAGGCATTGCCCCAAATACAATGTTAGCAAAAGTATGCAGTGATAAGAATAAACCAAAT
GGACAATACCAAATTCTTCCCAATAGACAAGCTGTGATGGACTTCATCAAGGATTTACCCATTAGAAAGGTTTCTGGAATAGGAAAAGTT
ACAGAGAAAATGTTAAAGGCCCTTGGAATTATTACATGTACAGAACTTTACCAACAGAGGGCATTGCTTTCTCTCCTTTTCTCTGAAACA
TCTTGGCATTATTTCCTTCATATCTCCTTGGGTCTAGGTTCAACACACCTGACGAGGGATGGAGAGAGGAAAAGTATGAGCGTTGAGAGG
TATGCCATTGCATTGGCCTTAAGGGAAAAGCAGCGTGTAATATTTACCAGCCCAATTAAGGCTCTGAGTAACCAAAAATACCGTGAAATG
TATGAAGAATTTCAAGATGTTGGTTTGATGACTGGTGATGTTACTATTAATCCTACGGCATCTTGTCTTGTTATGACCACAGAGATTTTG
AGAAGTATGCTTTACAGAGGTTCCGAAGTTATGAGAGAAGTTGCTTGGGTTATATTTGATGAAATTCATTATATGAGAGATTCAGAACGT
GGTGTAGTATGGGAAGAAACTATTATTTTGCTTCCTGATAACGTCCACTATGTCTTTCTTTCGGCTACTATTCCAAATGCCCGACAGTTT
GCTGAATGGATTTGCCATTTACATAAACAGCCTTGTCATGTTATTTACACAGATTATCGGCCCACTCCATTGCAACACTACATTTTTCCA
GCAGGGGGAGATGGCCTGCATCTTGTGGTTGATGAAAATGGTGACTTCAGAGAAGATAATTTTAATACTGCAATGCAAGTGCTTCGAGAT
GCAGGTGATTTGGCCAAAGGAGACCAGAAAGGGCGGAAAGGAGGAACAAAAGGACCATCAAATGTTTTCAAAATTGTGAAGATGATTATG
GAAAGAAATTTCCAACCTGTGATTATTTTCAGTTTTAGTAAGAAAGATTGTGAAGCCTATGCACTTCAAATGACCAAATTAGATTTCAAC
ACAGATGAAGAAAAGAAGATGGTTGAAGAAGTATTCAGTAATGCAATTGATTGCTTATCCGATGAAGATAAAAAACTCCCTCAGGTAGAA
CATGTACTTCCTCTTTTGAAGAGGGGAATTGGTATTCACCATGGTGGTTTACTTCCTATTTTGAAAGAAACTATAGAAATTCTCTTTTCT
GAAGGATTGATAAAGGCCTTATTTGCCACGGAGACCTTTGCTATGGGAATTAACATGCCAGCTAGAACTGTTTTATTTACAAATGCCCGC
AAATTTGATGGGAAGGATTTCCGATGGATTTCTTCTGGTGAATACATTCAGATGTCTGGTCGTGCTGGAAGGAGAGGAATGGATGATAGA
GGAATTGTAATTCTTATGGTAGATGAAAAGATGAGCCCAACAATTGGAAAACAATTACTTAAGGGCTCCGCTGATCCTCTAAATAGTGCT
TTCCATTTGACCTACAACATGGTTTTGAACTTACTACGTGTAGAAGAAATTAATCCTGAGTACATGTTGGAAAAATCCTTCTACCAGTTT
CAGCATTATAGAGCAATTCCAGGAGTAGTAGAGAAGGTAAAGAATTCAGAAGAACAGTATAATAAAATAGTAATTCCCAATGAAGAAAGT
GTGGTTATCTATTATAAGATTAGACAGCAGCTTGCCAAATTGGGTAAAGAAATTGAAGAATATATTCACAAACCAAAATACTGCTTACCT
TTTCTACAACCAGGTCGTTTGGTAAAGGTAAAGAATGAAGGAGATGACTTTGGCTGGGGAGTAGTGGTGAATTTCTCAAAAAAGTCAAAT
GTTAAGCCTAACTCTGGTGAACTGGATCCTTTGTATGTAGTAGAAGTACTTCTGCGCTGTAGCAAAGAGAGCTTGAAAAATTCAGCTACA
GAAGCTGCAAAACCAGCTAAACCTGATGAGAAAGGAGAGATGCAGGTTGTCCCAGTTTTGGTGCATCTCCTGTCTGCTATCAGCAGTGTT
AGGCTTTACATTCCTAAAGACCTTCGGCCGGTGGACAATAGACAGAGTGTTTTAAAATCAATACAGGAAGTTCAGAAACGTTTTCCTGAC
GGCATCCCCTTATTAGACCCTATTGATGATATGGGCATTCAAGATCAAGGGCTGAAAAAAGTCATTCAGAAAGTAGAAGCTTTTGAGCAT
CGAATGTATTCTCATCCACTTCACAATGATCCAAATTTGGAAACTGTGTATACGCTTTGTGAAAAAAAAGCACAGATTGCAATAGATATT
AAATCTGCAAAGCGAGAACTGAAGAAAGCAAGAACAGTCCTACAAATGGATGAACTCAAATGTCGCAAACGTGTTTTAAGAAGGTTGGGA
TTTGCTACTTCTTCTGATGTAATAGAGATGAAAGGACGAGTGGCTTGTGAGATAAGCAGTGCTGATGAGCTCCTTCTAACTGAGATGATG
TTTAATGGCCTTTTCAATGACCTTTCTGCAGAACAGGCAACAGCATTATTAAGCTGCTTTGTGTTTCAAGAGAATTCTAGTGAGATGCCC
AAATTAACAGAACAATTAGCAGGACCACTTCGTCAAATGCAGGAATGTGCTAAAAGAATTGCAAAAGTTTCAGCAGAAGCCAAATTGGAA
ATTGATGAGGAAACTTATCTAAGCTCATTTAAACCTCACTTAATGGATGTAGTATATACCTGGGCAACTGGAGCTACATTTGCCCATATC
TGCAAAATGACAGATGTCTTTGAAGGCAGCATAATTCGTTGTATGAGGCGCCTGGAAGAATTGCTTCGACAAATGTGTCAAGCAGCAAAA
GCCATTGGAAACACTGAGCTGGAAAATAAATTTGCAGAAGGAATCACCAAAATCAAGAGAGATATTGTGTTTGCTGCCAGCCTCTACTTG
TAGAGTCAGCTAAAGGAATGTGAGATTTTAAATTATTGACCACCTGTTTGATTACAGTTGACTACAAATGCCTGCAAGTGTGGATTTGGT
TCTCCCATACATTTTAATATGTATTATATTTAAATCAAACATCATTCATAGAAAGCATATTACATACATGTTTATACATAAGCATTACAT
TTTTTTAATAAAAATGTATACAGGTGGGGCACTGTTTTGGTGGAAGGCTTGGAGTTTTTTTAATGAGTTTAGAGCTATTAGATAACCACT

>66960_66960_6_POLK-SKIV2L2_POLK_chr5_74882883_ENST00000504026_SKIV2L2_chr5_54635838_ENST00000545714_length(amino acids)=1290AA_BP=419
MDSTKEKCDSYKDDLLLRMGLNDNKAGMEGLDKEKINKIIMEATKGSRFYGNELKKEKQVNQRIENMMQQKAQITSQQLRKAQLQVDRFA
MELEQSRNLSNTIVHIDMDAFYAAVEMRDNPELKDKPIAVGSMSMLSTSNYHARRFGVRAAMPGFIAKRLCPQLIIVPPNFDKYRAVSKE
VKEILADYDPNFMAMSLDEAYLNITKHLEERQNWPEDKRRYFIKMGSSVENDNPGKEVNKLSEHERSISPLLFEESPSDVQPPGDPFQVN
FEEQNNPQILQNSVVFGTSAQEVVKEIRFRIEQKTTLTASAGIAPNTMLAKVCSDKNKPNGQYQILPNRQAVMDFIKDLPIRKVSGIGKV
TEKMLKALGIITCTELYQQRALLSLLFSETSWHYFLHISLGLGSTHLTRDGERKSMSVERYAIALALREKQRVIFTSPIKALSNQKYREM
YEEFQDVGLMTGDVTINPTASCLVMTTEILRSMLYRGSEVMREVAWVIFDEIHYMRDSERGVVWEETIILLPDNVHYVFLSATIPNARQF
AEWICHLHKQPCHVIYTDYRPTPLQHYIFPAGGDGLHLVVDENGDFREDNFNTAMQVLRDAGDLAKGDQKGRKGGTKGPSNVFKIVKMIM
ERNFQPVIIFSFSKKDCEAYALQMTKLDFNTDEEKKMVEEVFSNAIDCLSDEDKKLPQVEHVLPLLKRGIGIHHGGLLPILKETIEILFS
EGLIKALFATETFAMGINMPARTVLFTNARKFDGKDFRWISSGEYIQMSGRAGRRGMDDRGIVILMVDEKMSPTIGKQLLKGSADPLNSA
FHLTYNMVLNLLRVEEINPEYMLEKSFYQFQHYRAIPGVVEKVKNSEEQYNKIVIPNEESVVIYYKIRQQLAKLGKEIEEYIHKPKYCLP
FLQPGRLVKVKNEGDDFGWGVVVNFSKKSNVKPNSGELDPLYVVEVLLRCSKESLKNSATEAAKPAKPDEKGEMQVVPVLVHLLSAISSV
RLYIPKDLRPVDNRQSVLKSIQEVQKRFPDGIPLLDPIDDMGIQDQGLKKVIQKVEAFEHRMYSHPLHNDPNLETVYTLCEKKAQIAIDI
KSAKRELKKARTVLQMDELKCRKRVLRRLGFATSSDVIEMKGRVACEISSADELLLTEMMFNGLFNDLSAEQATALLSCFVFQENSSEMP
KLTEQLAGPLRQMQECAKRIAKVSAEAKLEIDEETYLSSFKPHLMDVVYTWATGATFAHICKMTDVFEGSIIRCMRRLEELLRQMCQAAK

--------------------------------------------------------------
>66960_66960_7_POLK-SKIV2L2_POLK_chr5_74882883_ENST00000515295_SKIV2L2_chr5_54635838_ENST00000230640_length(transcript)=4695nt_BP=1272nt
ATAAGTTTATACCATGGATAGCACAAAGGAGAAGTGTGACAGTTACAAAGATGATCTTCTGCTTAGGATGGGACTTAATGATAATAAAGC
AGGAATGGAAGGATTAGATAAAGAGAAAATTAACAAAATTATAATGGAAGCCACGAAGGGGTCCAGATTTTATGGAAATGAGCTCAAGAA
AGAAAAGCAAGTCAACCAACGAATTGAAAATATGATGCAACAAAAAGCTCAAATCACCAGCCAACAGCTAAGAAAAGCACAATTACAGGT
TGACAGATTTGCAATGGAATTAGAACAAAGCCGAAATTTGAGCAATACCATAGTGCACATTGACATGGATGCTTTCTATGCAGCTGTAGA
AATGAGGGACAATCCAGAATTGAAGGATAAACCCATTGCTGTAGGATCAATGAGTATGCTGTCTACTTCAAATTACCATGCAAGGAGATT
TGGTGTTCGTGCAGCCATGCCAGGATTTATTGCTAAGAGGCTGTGCCCACAACTTATAATAGTGCCCCCCAACTTTGACAAATACCGAGC
TGTGAGTAAAGAGGTTAAGGAAATACTTGCTGATTATGATCCCAATTTTATGGCCATGAGTCTTGATGAAGCCTACTTGAATATAACAAA
GCACTTAGAAGAAAGACAAAATTGGCCTGAGGATAAAAGAAGGTATTTCATCAAAATGGGAAGCTCTGTAGAAAATGATAATCCAGGAAA
GGAAGTTAATAAACTGAGTGAGCATGAACGATCCATCTCTCCACTACTTTTTGAAGAGAGTCCTTCTGATGTGCAGCCCCCAGGAGATCC
TTTCCAAGTGAACTTTGAAGAACAAAACAATCCTCAAATACTCCAAAACTCAGTTGTTTTTGGAACATCAGCCCAGGAAGTGGTAAAGGA
AATTCGTTTCAGAATTGAGCAGAAAACAACACTGACAGCCAGTGCAGGCATTGCCCCAAATACAATGTTAGCAAAAGTATGCAGTGATAA
GAATAAACCAAATGGACAATACCAAATTCTTCCCAATAGACAAGCTGTGATGGACTTCATCAAGGATTTACCCATTAGAAAGGTTTCTGG
AATAGGAAAAGTTACAGAGAAAATGTTAAAGGCCCTTGGAATTATTACATGTACAGAACTTTACCAACAGAGGGCATTGCTTTCTCTCCT
TTTCTCTGAAACATCTTGGCATTATTTCCTTCATATCTCCTTGGGTCTAGGTTCAACACACCTGACGAGGGATGGAGAGAGGAAAAGTAT
GAGCGTTGAGAGGTATGCCATTGCATTGGCCTTAAGGGAAAAGCAGCGTGTAATATTTACCAGCCCAATTAAGGCTCTGAGTAACCAAAA
ATACCGTGAAATGTATGAAGAATTTCAAGATGTTGGTTTGATGACTGGTGATGTTACTATTAATCCTACGGCATCTTGTCTTGTTATGAC
CACAGAGATTTTGAGAAGTATGCTTTACAGAGGTTCCGAAGTTATGAGAGAAGTTGCTTGGGTTATATTTGATGAAATTCATTATATGAG
AGATTCAGAACGTGGTGTAGTATGGGAAGAAACTATTATTTTGCTTCCTGATAACGTCCACTATGTCTTTCTTTCGGCTACTATTCCAAA
TGCCCGACAGTTTGCTGAATGGATTTGCCATTTACATAAACAGCCTTGTCATGTTATTTACACAGATTATCGGCCCACTCCATTGCAACA
CTACATTTTTCCAGCAGGGGGAGATGGCCTGCATCTTGTGGTTGATGAAAATGGTGACTTCAGAGAAGATAATTTTAATACTGCAATGCA
AGTGCTTCGAGATGCAGGTGATTTGGCCAAAGGAGACCAGAAAGGGCGGAAAGGAGGAACAAAAGGACCATCAAATGTTTTCAAAATTGT
GAAGATGATTATGGAAAGAAATTTCCAACCTGTGATTATTTTCAGTTTTAGTAAGAAAGATTGTGAAGCCTATGCACTTCAAATGACCAA
ATTAGATTTCAACACAGATGAAGAAAAGAAGATGGTTGAAGAAGTATTCAGTAATGCAATTGATTGCTTATCCGATGAAGATAAAAAACT
CCCTCAGGTAGAACATGTACTTCCTCTTTTGAAGAGGGGAATTGGTATTCACCATGGTGGTTTACTTCCTATTTTGAAAGAAACTATAGA
AATTCTCTTTTCTGAAGGATTGATAAAGGCCTTATTTGCCACGGAGACCTTTGCTATGGGAATTAACATGCCAGCTAGAACTGTTTTATT
TACAAATGCCCGCAAATTTGATGGGAAGGATTTCCGATGGATTTCTTCTGGTGAATACATTCAGATGTCTGGTCGTGCTGGAAGGAGAGG
AATGGATGATAGAGGAATTGTAATTCTTATGGTAGATGAAAAGATGAGCCCAACAATTGGAAAACAATTACTTAAGGGCTCCGCTGATCC
TCTAAATAGTGCTTTCCATTTGACCTACAACATGGTTTTGAACTTACTACGTGTAGAAGAAATTAATCCTGAGTACATGTTGGAAAAATC
CTTCTACCAGTTTCAGCATTATAGAGCAATTCCAGGAGTAGTAGAGAAGGTAAAGAATTCAGAAGAACAGTATAATAAAATAGTAATTCC
CAATGAAGAAAGTGTGGTTATCTATTATAAGATTAGACAGCAGCTTGCCAAATTGGGTAAAGAAATTGAAGAATATATTCACAAACCAAA
ATACTGCTTACCTTTTCTACAACCAGGTCGTTTGGTAAAGGTAAAGAATGAAGGAGATGACTTTGGCTGGGGAGTAGTGGTGAATTTCTC
AAAAAAGTCAAATGTTAAGCCTAACTCTGGTGAACTGGATCCTTTGTATGTAGTAGAAGTACTTCTGCGCTGTAGCAAAGAGAGCTTGAA
AAATTCAGCTACAGAAGCTGCAAAACCAGCTAAACCTGATGAGAAAGGAGAGATGCAGGTTGTCCCAGTTTTGGTGCATCTCCTGTCTGC
TATCAGCAGTGTTAGGCTTTACATTCCTAAAGACCTTCGGCCGGTGGACAATAGACAGAGTGTTTTAAAATCAATACAGGAAGTTCAGAA
ACGTTTTCCTGACGGCATCCCCTTATTAGACCCTATTGATGATATGGGCATTCAAGATCAAGGGCTGAAAAAAGTCATTCAGAAAGTAGA
AGCTTTTGAGCATCGAATGTATTCTCATCCACTTCACAATGATCCAAATTTGGAAACTGTGTATACGCTTTGTGAAAAAAAAGCACAGAT
TGCAATAGATATTAAATCTGCAAAGCGAGAACTGAAGAAAGCAAGAACAGTCCTACAAATGGATGAACTCAAATGTCGCAAACGTGTTTT
AAGAAGGTTGGGATTTGCTACTTCTTCTGATGTAATAGAGATGAAAGGACGAGTGGCTTGTGAGATAAGCAGTGCTGATGAGCTCCTTCT
AACTGAGATGATGTTTAATGGCCTTTTCAATGACCTTTCTGCAGAACAGGCAACAGCATTATTAAGCTGCTTTGTGTTTCAAGAGAATTC
TAGTGAGATGCCCAAATTAACAGAACAATTAGCAGGACCACTTCGTCAAATGCAGGAATGTGCTAAAAGAATTGCAAAAGTTTCAGCAGA
AGCCAAATTGGAAATTGATGAGGAAACTTATCTAAGCTCATTTAAACCTCACTTAATGGATGTAGTATATACCTGGGCAACTGGAGCTAC
ATTTGCCCATATCTGCAAAATGACAGATGTCTTTGAAGGCAGCATAATTCGTTGTATGAGGCGCCTGGAAGAATTGCTTCGACAAATGTG
TCAAGCAGCAAAAGCCATTGGAAACACTGAGCTGGAAAATAAATTTGCAGAAGGAATCACCAAAATCAAGAGAGATATTGTGTTTGCTGC
CAGCCTCTACTTGTAGAGTCAGCTAAAGGAATGTGAGATTTTAAATTATTGACCACCTGTTTGATTACAGTTGACTACAAATGCCTGCAA
GTGTGGATTTGGTTCTCCCATACATTTTAATATGTATTATATTTAAATCAAACATCATTCATAGAAAGCATATTACATACATGTTTATAC
ATAAGCATTACATTTTTTTAATAAAAATGTATACAGGTGGGGCACTGTTTTGGTGGAAGGCTTGGAGTTTTTTTAATGAGTTTAGAGCTA
TTAGATAACCACTGAGTTAAAGGTAACTATGTACACACAAAGTGTGCATCCAAGAGGCATAGCAGCAGCAGAAGTCTTTAAAGGCTTGTA
CACCAGGAAGAAAGATGCATCCTCTTGCCTTGTGGCAATCATTTTCCTTTAGAAAACAGGCCAGCTTCACCTGGGCACCCTGCTGCCTTT
CAAGGCTGGTGATTGCTCGGATAGTGATTCCCAGTTGTTGGTGTTTCATGCAGAGTTGTATGAGAGTCCTCCTCTTTTCTTTCTTTAAAA
GAAGTTCTTTCTTTGAAGAAATCCGATACATATACAGCCTACAGTGCAAAATATTTAATGGTATAATTTAGATCAAGTTAAAAACTACAT
ACAAAGTTGTGATCAACAGCATCCTAAGATAAATATAAACAAAAGGATATACTTTGAGGTGTACAGATTAAGCATATAAAAAATTAGAGA
CTAACTGGGATTTTTTAAAGATTATTCCAAATTAAGAGTTGCTTTGTTATGCCTTCAGCAAATAGCTTCATTTTGCCAATACTGAATAAA

>66960_66960_7_POLK-SKIV2L2_POLK_chr5_74882883_ENST00000515295_SKIV2L2_chr5_54635838_ENST00000230640_length(amino acids)=1290AA_BP=419
MDSTKEKCDSYKDDLLLRMGLNDNKAGMEGLDKEKINKIIMEATKGSRFYGNELKKEKQVNQRIENMMQQKAQITSQQLRKAQLQVDRFA
MELEQSRNLSNTIVHIDMDAFYAAVEMRDNPELKDKPIAVGSMSMLSTSNYHARRFGVRAAMPGFIAKRLCPQLIIVPPNFDKYRAVSKE
VKEILADYDPNFMAMSLDEAYLNITKHLEERQNWPEDKRRYFIKMGSSVENDNPGKEVNKLSEHERSISPLLFEESPSDVQPPGDPFQVN
FEEQNNPQILQNSVVFGTSAQEVVKEIRFRIEQKTTLTASAGIAPNTMLAKVCSDKNKPNGQYQILPNRQAVMDFIKDLPIRKVSGIGKV
TEKMLKALGIITCTELYQQRALLSLLFSETSWHYFLHISLGLGSTHLTRDGERKSMSVERYAIALALREKQRVIFTSPIKALSNQKYREM
YEEFQDVGLMTGDVTINPTASCLVMTTEILRSMLYRGSEVMREVAWVIFDEIHYMRDSERGVVWEETIILLPDNVHYVFLSATIPNARQF
AEWICHLHKQPCHVIYTDYRPTPLQHYIFPAGGDGLHLVVDENGDFREDNFNTAMQVLRDAGDLAKGDQKGRKGGTKGPSNVFKIVKMIM
ERNFQPVIIFSFSKKDCEAYALQMTKLDFNTDEEKKMVEEVFSNAIDCLSDEDKKLPQVEHVLPLLKRGIGIHHGGLLPILKETIEILFS
EGLIKALFATETFAMGINMPARTVLFTNARKFDGKDFRWISSGEYIQMSGRAGRRGMDDRGIVILMVDEKMSPTIGKQLLKGSADPLNSA
FHLTYNMVLNLLRVEEINPEYMLEKSFYQFQHYRAIPGVVEKVKNSEEQYNKIVIPNEESVVIYYKIRQQLAKLGKEIEEYIHKPKYCLP
FLQPGRLVKVKNEGDDFGWGVVVNFSKKSNVKPNSGELDPLYVVEVLLRCSKESLKNSATEAAKPAKPDEKGEMQVVPVLVHLLSAISSV
RLYIPKDLRPVDNRQSVLKSIQEVQKRFPDGIPLLDPIDDMGIQDQGLKKVIQKVEAFEHRMYSHPLHNDPNLETVYTLCEKKAQIAIDI
KSAKRELKKARTVLQMDELKCRKRVLRRLGFATSSDVIEMKGRVACEISSADELLLTEMMFNGLFNDLSAEQATALLSCFVFQENSSEMP
KLTEQLAGPLRQMQECAKRIAKVSAEAKLEIDEETYLSSFKPHLMDVVYTWATGATFAHICKMTDVFEGSIIRCMRRLEELLRQMCQAAK

--------------------------------------------------------------
>66960_66960_8_POLK-SKIV2L2_POLK_chr5_74882883_ENST00000515295_SKIV2L2_chr5_54635838_ENST00000545714_length(transcript)=4220nt_BP=1272nt
ATAAGTTTATACCATGGATAGCACAAAGGAGAAGTGTGACAGTTACAAAGATGATCTTCTGCTTAGGATGGGACTTAATGATAATAAAGC
AGGAATGGAAGGATTAGATAAAGAGAAAATTAACAAAATTATAATGGAAGCCACGAAGGGGTCCAGATTTTATGGAAATGAGCTCAAGAA
AGAAAAGCAAGTCAACCAACGAATTGAAAATATGATGCAACAAAAAGCTCAAATCACCAGCCAACAGCTAAGAAAAGCACAATTACAGGT
TGACAGATTTGCAATGGAATTAGAACAAAGCCGAAATTTGAGCAATACCATAGTGCACATTGACATGGATGCTTTCTATGCAGCTGTAGA
AATGAGGGACAATCCAGAATTGAAGGATAAACCCATTGCTGTAGGATCAATGAGTATGCTGTCTACTTCAAATTACCATGCAAGGAGATT
TGGTGTTCGTGCAGCCATGCCAGGATTTATTGCTAAGAGGCTGTGCCCACAACTTATAATAGTGCCCCCCAACTTTGACAAATACCGAGC
TGTGAGTAAAGAGGTTAAGGAAATACTTGCTGATTATGATCCCAATTTTATGGCCATGAGTCTTGATGAAGCCTACTTGAATATAACAAA
GCACTTAGAAGAAAGACAAAATTGGCCTGAGGATAAAAGAAGGTATTTCATCAAAATGGGAAGCTCTGTAGAAAATGATAATCCAGGAAA
GGAAGTTAATAAACTGAGTGAGCATGAACGATCCATCTCTCCACTACTTTTTGAAGAGAGTCCTTCTGATGTGCAGCCCCCAGGAGATCC
TTTCCAAGTGAACTTTGAAGAACAAAACAATCCTCAAATACTCCAAAACTCAGTTGTTTTTGGAACATCAGCCCAGGAAGTGGTAAAGGA
AATTCGTTTCAGAATTGAGCAGAAAACAACACTGACAGCCAGTGCAGGCATTGCCCCAAATACAATGTTAGCAAAAGTATGCAGTGATAA
GAATAAACCAAATGGACAATACCAAATTCTTCCCAATAGACAAGCTGTGATGGACTTCATCAAGGATTTACCCATTAGAAAGGTTTCTGG
AATAGGAAAAGTTACAGAGAAAATGTTAAAGGCCCTTGGAATTATTACATGTACAGAACTTTACCAACAGAGGGCATTGCTTTCTCTCCT
TTTCTCTGAAACATCTTGGCATTATTTCCTTCATATCTCCTTGGGTCTAGGTTCAACACACCTGACGAGGGATGGAGAGAGGAAAAGTAT
GAGCGTTGAGAGGTATGCCATTGCATTGGCCTTAAGGGAAAAGCAGCGTGTAATATTTACCAGCCCAATTAAGGCTCTGAGTAACCAAAA
ATACCGTGAAATGTATGAAGAATTTCAAGATGTTGGTTTGATGACTGGTGATGTTACTATTAATCCTACGGCATCTTGTCTTGTTATGAC
CACAGAGATTTTGAGAAGTATGCTTTACAGAGGTTCCGAAGTTATGAGAGAAGTTGCTTGGGTTATATTTGATGAAATTCATTATATGAG
AGATTCAGAACGTGGTGTAGTATGGGAAGAAACTATTATTTTGCTTCCTGATAACGTCCACTATGTCTTTCTTTCGGCTACTATTCCAAA
TGCCCGACAGTTTGCTGAATGGATTTGCCATTTACATAAACAGCCTTGTCATGTTATTTACACAGATTATCGGCCCACTCCATTGCAACA
CTACATTTTTCCAGCAGGGGGAGATGGCCTGCATCTTGTGGTTGATGAAAATGGTGACTTCAGAGAAGATAATTTTAATACTGCAATGCA
AGTGCTTCGAGATGCAGGTGATTTGGCCAAAGGAGACCAGAAAGGGCGGAAAGGAGGAACAAAAGGACCATCAAATGTTTTCAAAATTGT
GAAGATGATTATGGAAAGAAATTTCCAACCTGTGATTATTTTCAGTTTTAGTAAGAAAGATTGTGAAGCCTATGCACTTCAAATGACCAA
ATTAGATTTCAACACAGATGAAGAAAAGAAGATGGTTGAAGAAGTATTCAGTAATGCAATTGATTGCTTATCCGATGAAGATAAAAAACT
CCCTCAGGTAGAACATGTACTTCCTCTTTTGAAGAGGGGAATTGGTATTCACCATGGTGGTTTACTTCCTATTTTGAAAGAAACTATAGA
AATTCTCTTTTCTGAAGGATTGATAAAGGCCTTATTTGCCACGGAGACCTTTGCTATGGGAATTAACATGCCAGCTAGAACTGTTTTATT
TACAAATGCCCGCAAATTTGATGGGAAGGATTTCCGATGGATTTCTTCTGGTGAATACATTCAGATGTCTGGTCGTGCTGGAAGGAGAGG
AATGGATGATAGAGGAATTGTAATTCTTATGGTAGATGAAAAGATGAGCCCAACAATTGGAAAACAATTACTTAAGGGCTCCGCTGATCC
TCTAAATAGTGCTTTCCATTTGACCTACAACATGGTTTTGAACTTACTACGTGTAGAAGAAATTAATCCTGAGTACATGTTGGAAAAATC
CTTCTACCAGTTTCAGCATTATAGAGCAATTCCAGGAGTAGTAGAGAAGGTAAAGAATTCAGAAGAACAGTATAATAAAATAGTAATTCC
CAATGAAGAAAGTGTGGTTATCTATTATAAGATTAGACAGCAGCTTGCCAAATTGGGTAAAGAAATTGAAGAATATATTCACAAACCAAA
ATACTGCTTACCTTTTCTACAACCAGGTCGTTTGGTAAAGGTAAAGAATGAAGGAGATGACTTTGGCTGGGGAGTAGTGGTGAATTTCTC
AAAAAAGTCAAATGTTAAGCCTAACTCTGGTGAACTGGATCCTTTGTATGTAGTAGAAGTACTTCTGCGCTGTAGCAAAGAGAGCTTGAA
AAATTCAGCTACAGAAGCTGCAAAACCAGCTAAACCTGATGAGAAAGGAGAGATGCAGGTTGTCCCAGTTTTGGTGCATCTCCTGTCTGC
TATCAGCAGTGTTAGGCTTTACATTCCTAAAGACCTTCGGCCGGTGGACAATAGACAGAGTGTTTTAAAATCAATACAGGAAGTTCAGAA
ACGTTTTCCTGACGGCATCCCCTTATTAGACCCTATTGATGATATGGGCATTCAAGATCAAGGGCTGAAAAAAGTCATTCAGAAAGTAGA
AGCTTTTGAGCATCGAATGTATTCTCATCCACTTCACAATGATCCAAATTTGGAAACTGTGTATACGCTTTGTGAAAAAAAAGCACAGAT
TGCAATAGATATTAAATCTGCAAAGCGAGAACTGAAGAAAGCAAGAACAGTCCTACAAATGGATGAACTCAAATGTCGCAAACGTGTTTT
AAGAAGGTTGGGATTTGCTACTTCTTCTGATGTAATAGAGATGAAAGGACGAGTGGCTTGTGAGATAAGCAGTGCTGATGAGCTCCTTCT
AACTGAGATGATGTTTAATGGCCTTTTCAATGACCTTTCTGCAGAACAGGCAACAGCATTATTAAGCTGCTTTGTGTTTCAAGAGAATTC
TAGTGAGATGCCCAAATTAACAGAACAATTAGCAGGACCACTTCGTCAAATGCAGGAATGTGCTAAAAGAATTGCAAAAGTTTCAGCAGA
AGCCAAATTGGAAATTGATGAGGAAACTTATCTAAGCTCATTTAAACCTCACTTAATGGATGTAGTATATACCTGGGCAACTGGAGCTAC
ATTTGCCCATATCTGCAAAATGACAGATGTCTTTGAAGGCAGCATAATTCGTTGTATGAGGCGCCTGGAAGAATTGCTTCGACAAATGTG
TCAAGCAGCAAAAGCCATTGGAAACACTGAGCTGGAAAATAAATTTGCAGAAGGAATCACCAAAATCAAGAGAGATATTGTGTTTGCTGC
CAGCCTCTACTTGTAGAGTCAGCTAAAGGAATGTGAGATTTTAAATTATTGACCACCTGTTTGATTACAGTTGACTACAAATGCCTGCAA
GTGTGGATTTGGTTCTCCCATACATTTTAATATGTATTATATTTAAATCAAACATCATTCATAGAAAGCATATTACATACATGTTTATAC
ATAAGCATTACATTTTTTTAATAAAAATGTATACAGGTGGGGCACTGTTTTGGTGGAAGGCTTGGAGTTTTTTTAATGAGTTTAGAGCTA

>66960_66960_8_POLK-SKIV2L2_POLK_chr5_74882883_ENST00000515295_SKIV2L2_chr5_54635838_ENST00000545714_length(amino acids)=1290AA_BP=419
MDSTKEKCDSYKDDLLLRMGLNDNKAGMEGLDKEKINKIIMEATKGSRFYGNELKKEKQVNQRIENMMQQKAQITSQQLRKAQLQVDRFA
MELEQSRNLSNTIVHIDMDAFYAAVEMRDNPELKDKPIAVGSMSMLSTSNYHARRFGVRAAMPGFIAKRLCPQLIIVPPNFDKYRAVSKE
VKEILADYDPNFMAMSLDEAYLNITKHLEERQNWPEDKRRYFIKMGSSVENDNPGKEVNKLSEHERSISPLLFEESPSDVQPPGDPFQVN
FEEQNNPQILQNSVVFGTSAQEVVKEIRFRIEQKTTLTASAGIAPNTMLAKVCSDKNKPNGQYQILPNRQAVMDFIKDLPIRKVSGIGKV
TEKMLKALGIITCTELYQQRALLSLLFSETSWHYFLHISLGLGSTHLTRDGERKSMSVERYAIALALREKQRVIFTSPIKALSNQKYREM
YEEFQDVGLMTGDVTINPTASCLVMTTEILRSMLYRGSEVMREVAWVIFDEIHYMRDSERGVVWEETIILLPDNVHYVFLSATIPNARQF
AEWICHLHKQPCHVIYTDYRPTPLQHYIFPAGGDGLHLVVDENGDFREDNFNTAMQVLRDAGDLAKGDQKGRKGGTKGPSNVFKIVKMIM
ERNFQPVIIFSFSKKDCEAYALQMTKLDFNTDEEKKMVEEVFSNAIDCLSDEDKKLPQVEHVLPLLKRGIGIHHGGLLPILKETIEILFS
EGLIKALFATETFAMGINMPARTVLFTNARKFDGKDFRWISSGEYIQMSGRAGRRGMDDRGIVILMVDEKMSPTIGKQLLKGSADPLNSA
FHLTYNMVLNLLRVEEINPEYMLEKSFYQFQHYRAIPGVVEKVKNSEEQYNKIVIPNEESVVIYYKIRQQLAKLGKEIEEYIHKPKYCLP
FLQPGRLVKVKNEGDDFGWGVVVNFSKKSNVKPNSGELDPLYVVEVLLRCSKESLKNSATEAAKPAKPDEKGEMQVVPVLVHLLSAISSV
RLYIPKDLRPVDNRQSVLKSIQEVQKRFPDGIPLLDPIDDMGIQDQGLKKVIQKVEAFEHRMYSHPLHNDPNLETVYTLCEKKAQIAIDI
KSAKRELKKARTVLQMDELKCRKRVLRRLGFATSSDVIEMKGRVACEISSADELLLTEMMFNGLFNDLSAEQATALLSCFVFQENSSEMP
KLTEQLAGPLRQMQECAKRIAKVSAEAKLEIDEETYLSSFKPHLMDVVYTWATGATFAHICKMTDVFEGSIIRCMRRLEELLRQMCQAAK

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Fusion Gene PPI Analysis for POLK-SKIV2L2


check button Go to ChiPPI (Chimeric Protein-Protein interactions) to see the chimeric PPI interaction in

ChiPPI page.


check button Protein-protein interactors with each fusion partner protein in wild-type (BIOGRID-3.4.160)
HgeneHgene's interactorsTgeneTgene's interactors


check button - Retained PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenStill interaction with


check button - Lost PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


check button - Retained PPIs, but lost function due to frame-shift fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


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Related Drugs for POLK-SKIV2L2


check button Drugs targeting genes involved in this fusion gene.
(DrugBank Version 5.1.8 2021-05-08)
PartnerGeneUniProtAccDrugBank IDDrug nameDrug activityDrug typeDrug status

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Related Diseases for POLK-SKIV2L2


check button Diseases associated with fusion partners.
(DisGeNet 4.0)
PartnerGeneDisease IDDisease name# pubmedsSource