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Center for Computational Systems Medicine
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Fusion Gene Summary

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Fusion Gene ORF analysis

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Fusion Genomic Features

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Fusion Protein Features

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Fusion Gene Sequence

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Fusion Gene PPI analysis

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Related Drugs

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Related Diseases

Fusion gene:POLR2A-ASAP2 (FusionGDB2 ID:67000)

Fusion Gene Summary for POLR2A-ASAP2

check button Fusion gene summary
Fusion gene informationFusion gene name: POLR2A-ASAP2
Fusion gene ID: 67000
HgeneTgene
Gene symbol

POLR2A

ASAP2

Gene ID

5430

8853

Gene nameRNA polymerase II subunit AArfGAP with SH3 domain, ankyrin repeat and PH domain 2
SynonymsNEDHIB|POLR2|POLRA|RPB1|RPBh1|RPO2|RPOL2|RpIILS|hRPB220|hsRPB1AMAP2|CENTB3|DDEF2|PAG3|PAP|Pap-alpha|SHAG1
Cytomap

17p13.1

2p25.1|2p24

Type of geneprotein-codingprotein-coding
DescriptionDNA-directed RNA polymerase II subunit RPB1DNA-directed RNA polymerase II largest subunit, RNA polymerase II 220 kd subunitDNA-directed RNA polymerase II subunit ADNA-directed RNA polymerase III largest subunitRNA polymerase II subunit B1RNA-directedarf-GAP with SH3 domain, ANK repeat and PH domain-containing protein 2PYK2 C terminus-associated proteincentaurin, beta 3development and differentiation-enhancing factor 2paxillin-associated protein with ARF GAP activity 3pyk2 C-terminus-associated p
Modification date2020032720200327
UniProtAcc.

O43150

Ensembl transtripts involved in fusion geneENST00000322644, ENST00000572844, 
ENST00000491413, ENST00000281419, 
ENST00000315273, 
Fusion gene scores* DoF score12 X 8 X 6=5769 X 10 X 4=360
# samples 1311
** MAII scorelog2(13/576*10)=-2.14755718841386
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0		log2(11/360*10)=-1.71049338280502
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0
Context

PubMed: POLR2A [Title/Abstract] AND ASAP2 [Title/Abstract] AND fusion [Title/Abstract]

Most frequent breakpointPOLR2A(7388176)-ASAP2(9419446), # samples:2
Anticipated loss of major functional domain due to fusion event.
* DoF score (Degree of Frequency) = # partners X # break points X # cancer types
** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10)

check button Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez
PartnerGeneGO IDGO termPubMed ID
HgenePOLR2A

GO:0006366

transcription by RNA polymerase II

9852112

HgenePOLR2A

GO:0033120

positive regulation of RNA splicing

21536736


check buttonFusion gene breakpoints across POLR2A (5'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.
all structure

check buttonFusion gene breakpoints across ASAP2 (3'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.
all structure

check button Fusion gene information from two resources (ChiTars 5.0 and ChimerDB 4.0)
* All genome coordinats were lifted-over on hg19.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
SourceDiseaseSampleHgeneHchrHbpHstrandTgeneTchrTbpTstrand
ChimerDB4GBMTCGA-06-2558-01APOLR2Achr17

7388176

+ASAP2chr2

9419446

+


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Fusion Gene ORF analysis for POLR2A-ASAP2

check button Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
ORFHenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrand
5CDS-intronENST00000322644ENST00000491413POLR2Achr17

7388176

+ASAP2chr2

9419446

+
5CDS-intronENST00000572844ENST00000491413POLR2Achr17

7388176

+ASAP2chr2

9419446

+
In-frameENST00000322644ENST00000281419POLR2Achr17

7388176

+ASAP2chr2

9419446

+
In-frameENST00000322644ENST00000315273POLR2Achr17

7388176

+ASAP2chr2

9419446

+
In-frameENST00000572844ENST00000281419POLR2Achr17

7388176

+ASAP2chr2

9419446

+
In-frameENST00000572844ENST00000315273POLR2Achr17

7388176

+ASAP2chr2

9419446

+

check buttonORFfinder result based on the fusion transcript sequence of in-frame fusion genes.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandSeq length
(transcript)		BP loci
(transcript)		Predicted start
(transcript)		Predicted stop
(transcript)		Seq length
(amino acids)
ENST00000322644POLR2Achr177388176+ENST00000281419ASAP2chr29419446+573849236933861005
ENST00000322644POLR2Achr177388176+ENST00000315273ASAP2chr29419446+56084923693251960
ENST00000572844POLR2Achr177388176+ENST00000281419ASAP2chr29419446+548423811531321005
ENST00000572844POLR2Achr177388176+ENST00000315273ASAP2chr29419446+53542381152997960

check buttonDeepORF prediction of the coding potential based on the fusion transcript sequence of in-frame fusion genes. DeepORF is a coding potential classifier based on convolutional neural network by comparing the real Ribo-seq data. If the no-coding score < 0.5 and coding score > 0.5, then the in-frame fusion transcript is predicted as being likely translated.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandNo-coding scoreCoding score
ENST00000322644ENST00000281419POLR2Achr177388176+ASAP2chr29419446+0.0004277170.99957234
ENST00000322644ENST00000315273POLR2Achr177388176+ASAP2chr29419446+0.0003973010.99960274
ENST00000572844ENST00000281419POLR2Achr177388176+ASAP2chr29419446+0.0003904530.99960953
ENST00000572844ENST00000315273POLR2Achr177388176+ASAP2chr29419446+0.0004738540.99952614

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Fusion Genomic Features for POLR2A-ASAP2


check buttonFusionAI prediction of the potential fusion gene breakpoint based on the pre-mature RNA sequence context (+/- 5kb of individual partner genes, total 20kb length sequence). FusionAI is a fusion gene breakpoint classifier based on convolutional neural network by comparing the fusion positive and negative sequence context of ~ 20K fusion gene data. From here, we can have the relative potentency of the 20K genomic sequence how individual sequnce will be likely used as the gene fusion breakpoints.
HgeneHchrHbpHstrandTgeneTchrTbpTstrand1-pp (fusion gene breakpoint)
POLR2Achr177388176+ASAP2chr29419445+0.0140391440.98596084
POLR2Achr177388176+ASAP2chr29419445+0.0140391440.98596084

check buttonDistribution of 44 human genomic features loci across 20kb length fusion breakpoint regions. We integrated a total of 44 different types of human genomic feature loci information across five big categories including virus integration sites, repeats, structural variants, chromatin states, and gene expression regulation. More details are in help page.
genomic feature

check buttonDistribution of 44 human genomic features loci across 20kb length fusion breakpoint regions that are ovelapped with the top 1% feature importance score regions. More details are in help page.
genomic feature of top 1%

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Fusion Protein Features for POLR2A-ASAP2


check button Four levels of functional features of fusion genes
Go to FGviewer search page for the most frequent breakpoint (https://ccsmweb.uth.edu/FGviewer/chr17:7388176/chr2:9419446)
- FGviewer provides the online visualization of the retention search of the protein functional features across DNA, RNA, protein, and pathological levels.
- How to search
1. Put your fusion gene symbol.
2. Press the tab key until there will be shown the breakpoint information filled.
4. Go down and press 'Search' tab twice.
4. Go down to have the hyperlink of the search result.
5. Click the hyperlink.
6. See the FGviewer result for your fusion gene.
FGviewer

check buttonMain function of each fusion partner protein. (from UniProt)
HgeneTgene
.ASAP2

O43150

FUNCTION: Transcriptional activator which is required for calcium-dependent dendritic growth and branching in cortical neurons. Recruits CREB-binding protein (CREBBP) to nuclear bodies. Component of the CREST-BRG1 complex, a multiprotein complex that regulates promoter activation by orchestrating a calcium-dependent release of a repressor complex and a recruitment of an activator complex. In resting neurons, transcription of the c-FOS promoter is inhibited by BRG1-dependent recruitment of a phospho-RB1-HDAC1 repressor complex. Upon calcium influx, RB1 is dephosphorylated by calcineurin, which leads to release of the repressor complex. At the same time, there is increased recruitment of CREBBP to the promoter by a CREST-dependent mechanism, which leads to transcriptional activation. The CREST-BRG1 complex also binds to the NR2B promoter, and activity-dependent induction of NR2B expression involves a release of HDAC1 and recruitment of CREBBP (By similarity). {ECO:0000250}.FUNCTION: Activates the small GTPases ARF1, ARF5 and ARF6. Regulates the formation of post-Golgi vesicles and modulates constitutive secretion. Modulates phagocytosis mediated by Fc gamma receptor and ARF6. Modulates PXN recruitment to focal contacts and cell migration. {ECO:0000269|PubMed:10022920, ECO:0000269|PubMed:10749932, ECO:0000269|PubMed:11304556}.

check buttonRetention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at

download page


* Minus value of BPloci means that the break pointn is located before the CDS.
- In-frame and retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
TgeneASAP2chr17:7388176chr2:9419446ENST00000281419028256_283421007.0Coiled coilOntology_term=ECO:0000255
TgeneASAP2chr17:7388176chr2:9419446ENST00000281419028729_752421007.0Coiled coilOntology_term=ECO:0000255
TgeneASAP2chr17:7388176chr2:9419446ENST00000315273027256_28342962.0Coiled coilOntology_term=ECO:0000255
TgeneASAP2chr17:7388176chr2:9419446ENST00000315273027729_75242962.0Coiled coilOntology_term=ECO:0000255
TgeneASAP2chr17:7388176chr2:9419446ENST00000281419028771_936421007.0Compositional biasNote=Pro-rich
TgeneASAP2chr17:7388176chr2:9419446ENST00000315273027771_93642962.0Compositional biasNote=Pro-rich
TgeneASAP2chr17:7388176chr2:9419446ENST00000281419028305_397421007.0DomainPH
TgeneASAP2chr17:7388176chr2:9419446ENST00000281419028421_543421007.0DomainArf-GAP
TgeneASAP2chr17:7388176chr2:9419446ENST00000281419028944_1006421007.0DomainSH3
TgeneASAP2chr17:7388176chr2:9419446ENST00000315273027305_39742962.0DomainPH
TgeneASAP2chr17:7388176chr2:9419446ENST00000315273027421_54342962.0DomainArf-GAP
TgeneASAP2chr17:7388176chr2:9419446ENST00000315273027944_100642962.0DomainSH3
TgeneASAP2chr17:7388176chr2:9419446ENST00000281419028584_616421007.0RepeatNote=ANK 1
TgeneASAP2chr17:7388176chr2:9419446ENST00000281419028620_649421007.0RepeatNote=ANK 2
TgeneASAP2chr17:7388176chr2:9419446ENST00000315273027584_61642962.0RepeatNote=ANK 1
TgeneASAP2chr17:7388176chr2:9419446ENST00000315273027620_64942962.0RepeatNote=ANK 2

- In-frame and not-retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
HgenePOLR2Achr17:7388176chr2:9419446ENST00000322644+1291593_1960311971.0RegionNote=C-terminal domain (CTD)%3B 52 X 7 AA approximate tandem repeats of Y-[ST]-P-[STQ]-[ST]-P-[SRTEVKGN]
HgenePOLR2Achr17:7388176chr2:9419446ENST00000322644+129833_845311971.0RegionNote=Bridging helix
HgenePOLR2Achr17:7388176chr2:9419446ENST00000322644+1291593_1599311971.0RepeatNote=1
HgenePOLR2Achr17:7388176chr2:9419446ENST00000322644+1291600_1606311971.0RepeatNote=2%3B approximate
HgenePOLR2Achr17:7388176chr2:9419446ENST00000322644+1291608_1614311971.0RepeatNote=3
HgenePOLR2Achr17:7388176chr2:9419446ENST00000322644+1291615_1621311971.0RepeatNote=4
HgenePOLR2Achr17:7388176chr2:9419446ENST00000322644+1291622_1628311971.0RepeatNote=5
HgenePOLR2Achr17:7388176chr2:9419446ENST00000322644+1291629_1635311971.0RepeatNote=6
HgenePOLR2Achr17:7388176chr2:9419446ENST00000322644+1291636_1642311971.0RepeatNote=7
HgenePOLR2Achr17:7388176chr2:9419446ENST00000322644+1291643_1649311971.0RepeatNote=8
HgenePOLR2Achr17:7388176chr2:9419446ENST00000322644+1291650_1656311971.0RepeatNote=9
HgenePOLR2Achr17:7388176chr2:9419446ENST00000322644+1291657_1663311971.0RepeatNote=10
HgenePOLR2Achr17:7388176chr2:9419446ENST00000322644+1291664_1670311971.0RepeatNote=11
HgenePOLR2Achr17:7388176chr2:9419446ENST00000322644+1291671_1677311971.0RepeatNote=12
HgenePOLR2Achr17:7388176chr2:9419446ENST00000322644+1291678_1684311971.0RepeatNote=13
HgenePOLR2Achr17:7388176chr2:9419446ENST00000322644+1291685_1691311971.0RepeatNote=14
HgenePOLR2Achr17:7388176chr2:9419446ENST00000322644+1291692_1698311971.0RepeatNote=15
HgenePOLR2Achr17:7388176chr2:9419446ENST00000322644+1291699_1705311971.0RepeatNote=16
HgenePOLR2Achr17:7388176chr2:9419446ENST00000322644+1291706_1712311971.0RepeatNote=17
HgenePOLR2Achr17:7388176chr2:9419446ENST00000322644+1291713_1719311971.0RepeatNote=18
HgenePOLR2Achr17:7388176chr2:9419446ENST00000322644+1291720_1726311971.0RepeatNote=19
HgenePOLR2Achr17:7388176chr2:9419446ENST00000322644+1291727_1733311971.0RepeatNote=20
HgenePOLR2Achr17:7388176chr2:9419446ENST00000322644+1291734_1740311971.0RepeatNote=21
HgenePOLR2Achr17:7388176chr2:9419446ENST00000322644+1291741_1747311971.0RepeatNote=22
HgenePOLR2Achr17:7388176chr2:9419446ENST00000322644+1291748_1754311971.0RepeatNote=23
HgenePOLR2Achr17:7388176chr2:9419446ENST00000322644+1291755_1761311971.0RepeatNote=24
HgenePOLR2Achr17:7388176chr2:9419446ENST00000322644+1291762_1768311971.0RepeatNote=25
HgenePOLR2Achr17:7388176chr2:9419446ENST00000322644+1291769_1775311971.0RepeatNote=26
HgenePOLR2Achr17:7388176chr2:9419446ENST00000322644+1291776_1782311971.0RepeatNote=27
HgenePOLR2Achr17:7388176chr2:9419446ENST00000322644+1291783_1789311971.0RepeatNote=28
HgenePOLR2Achr17:7388176chr2:9419446ENST00000322644+1291790_1796311971.0RepeatNote=29
HgenePOLR2Achr17:7388176chr2:9419446ENST00000322644+1291797_1803311971.0RepeatNote=30
HgenePOLR2Achr17:7388176chr2:9419446ENST00000322644+1291804_1810311971.0RepeatNote=31
HgenePOLR2Achr17:7388176chr2:9419446ENST00000322644+1291811_1817311971.0RepeatNote=32
HgenePOLR2Achr17:7388176chr2:9419446ENST00000322644+1291818_1824311971.0RepeatNote=33
HgenePOLR2Achr17:7388176chr2:9419446ENST00000322644+1291825_1831311971.0RepeatNote=34
HgenePOLR2Achr17:7388176chr2:9419446ENST00000322644+1291832_1838311971.0RepeatNote=35
HgenePOLR2Achr17:7388176chr2:9419446ENST00000322644+1291839_1845311971.0RepeatNote=36
HgenePOLR2Achr17:7388176chr2:9419446ENST00000322644+1291846_1852311971.0RepeatNote=37
HgenePOLR2Achr17:7388176chr2:9419446ENST00000322644+1291853_1859311971.0RepeatNote=38
HgenePOLR2Achr17:7388176chr2:9419446ENST00000322644+1291860_1866311971.0RepeatNote=39
HgenePOLR2Achr17:7388176chr2:9419446ENST00000322644+1291867_1873311971.0RepeatNote=40
HgenePOLR2Achr17:7388176chr2:9419446ENST00000322644+1291874_1880311971.0RepeatNote=41
HgenePOLR2Achr17:7388176chr2:9419446ENST00000322644+1291881_1887311971.0RepeatNote=42
HgenePOLR2Achr17:7388176chr2:9419446ENST00000322644+1291888_1894311971.0RepeatNote=43
HgenePOLR2Achr17:7388176chr2:9419446ENST00000322644+1291895_1901311971.0RepeatNote=44
HgenePOLR2Achr17:7388176chr2:9419446ENST00000322644+1291902_1908311971.0RepeatNote=45
HgenePOLR2Achr17:7388176chr2:9419446ENST00000322644+1291909_1915311971.0RepeatNote=46
HgenePOLR2Achr17:7388176chr2:9419446ENST00000322644+1291916_1922311971.0RepeatNote=47
HgenePOLR2Achr17:7388176chr2:9419446ENST00000322644+1291923_1929311971.0RepeatNote=48
HgenePOLR2Achr17:7388176chr2:9419446ENST00000322644+1291930_1936311971.0RepeatNote=49
HgenePOLR2Achr17:7388176chr2:9419446ENST00000322644+1291940_1946311971.0RepeatNote=50
HgenePOLR2Achr17:7388176chr2:9419446ENST00000322644+1291947_1953311971.0RepeatNote=51%3B approximate
HgenePOLR2Achr17:7388176chr2:9419446ENST00000322644+1291954_1960311971.0RepeatNote=52%3B approximate


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Fusion Gene Sequence for POLR2A-ASAP2


check button For in-frame fusion transcripts, we provide the fusion transcript sequences and fusion amino acid sequences. To have fusion amino acid sequence, we ran ORFfinder and chose the longest ORF among the all predicted ones.
>67000_67000_1_POLR2A-ASAP2_POLR2A_chr17_7388176_ENST00000322644_ASAP2_chr2_9419446_ENST00000281419_length(transcript)=5738nt_BP=492nt
GCTCAGAAGCGCCGAGAGCGCGGCCGGGACGGTTGGAGAAGAAGGCGGCTCCCGGAAGGGGGAGAGACAAACTGCCGTAACCTCTGCCGT
TCAGGAACCCGGTTACTTATTTATTCGTTACCCTTTTTCTTCTTCCTCCCCCAAAAACCTTTTCCTTTTCCCTTCTTTTTTTTTCCTTTT
TGGGAGCTGAAAAATTTCCGGTAAGGGAAAGAAGGGCTCCTTTCGCTCCTTATTTCCCCGCCTCCTTCCCTCCCCCACCTTCCCCTCCTC
CGGCTTTTTCCTCCCAACTCGGGGAGGTCCTTCCCGGTGGCCGCCCTGACGAGGTCTGAGCACCTAGGCGGAGGCGGCGCAGGCTTTTTG
TAGTGAGGTTTGCGCCTGCGCAGCGCGCCTGCCTCCGCCATGCACGGGGGTGGCCCCCCCTCGGGGGACAGCGCATGCCCGCTGCGCACC
ATCAAGAGAGTCCAGTTCGGAGTCCTGAGTCCGGATGAACTGGCTTTGGACGTGGACCGGATGGTTCTTTACAAAATGAAGAAATCCGTG
AAAGCAATCAACAGCTCTGGGCTGGCTCACGTGGAAAATGAAGAGCAGTACACCCAGGCTCTGGAGAAGTTTGGCGGCAACTGTGTATGC
AGAGATGACCCAGATTTAGGAAGTGCGTTCCTGAAGTTCTCAGTGTTTACAAAGGAGTTGACAGCACTTTTCAAAAACCTGATTCAGAAT
ATGAACAACATAATCTCCTTCCCTTTGGACAGTTTGCTGAAGGGGGACCTGAAAGGAGTGAAAGGGGATCTGAAAAAGCCTTTTGATAAA
GCTTGGAAGGACTATGAAACAAAAATAACCAAGATAGAAAAGGAGAAAAAGGAACACGCCAAGCTCCATGGGATGATTCGGACTGAAATA
AGCGGAGCGGAAATTGCCGAAGAGATGGAAAAGGAGAGGCGCTTCTTCCAGCTACAGATGTGCGAGTATCTGCTGAAGGTCAACGAAATC
AAGATTAAAAAGGGAGTAGATTTACTTCAGAATCTGATCAAATACTTTCATGCCCAATGCAATTTTTTTCAGGATGGACTCAAAGCCGTG
GAAAGCCTCAAACCTTCCATTGAAACGCTGTCTACGGATCTTCACACGATCAAACAGGCCCAGGATGAAGAAAGAAGGCAGTTGATACAG
CTTCGAGATATTTTGAAATCCGCATTGCAGGTTGAACAGAAAGAGGACTCCCAAATTCGTCAGAGCACAGCTTATAGCTTACATCAGCCT
CAGGGAAACAAGGAACATGGGACCGAGCGGAACGGCAGCCTCTACAAGAAGAGTGACGGGATCCGAAAAGTGTGGCAGAAAAGGAAATGT
TCAGTTAAAAATGGTTTTCTGACCATATCCCATGGTACCGCTAACCGGCCTCCTGCAAAGCTCAACCTGCTAACCTGCCAGGTGAAGACC
AACCCTGAGGAGAAGAAGTGCTTTGACCTCATTTCACATGACAGAACTTACCACTTTCAAGCTGAAGATGAACAGGAATGTCAAATATGG
ATGTCTGTGCTGCAAAATAGCAAAGAAGAAGCTTTAAACAATGCATTTAAGGGGGATGACAATACTGGAGAAAATAACATCGTCCAAGAA
CTGACAAAGGAGATCATCTCAGAAGTGCAGAGGATGACGGGCAATGACGTCTGCTGTGACTGTGGGGCGCCAGATCCTACATGGCTTTCC
ACCAACCTGGGCATCCTGACCTGCATCGAGTGTTCCGGAATCCACCGAGAGCTGGGGGTTCATTATTCCAGGATGCAGTCCCTGACCTTA
GATGTACTGGGAACATCTGAGCTGCTGCTCGCCAAGAATATTGGGAATGCAGGCTTTAATGAGATCATGGAATGTTGCCTACCAGCTGAG
GACTCAGTCAAACCCAACCCAGGCAGCGACATGAATGCAAGAAAGGACTACATCACAGCCAAGTACATCGAGAGGAGATACGCAAGGAAG
AAGCACGCGGATAACGCGGCGAAGCTTCACAGTCTTTGCGAGGCCGTCAAAACGAGAGATATTTTTGGATTGCTCCAAGCTTATGCTGAT
GGTGTGGATCTTACGGAAAAAATCCCACTGGCCAACGGACATGAGCCGGATGAAACGGCCCTCCACCTTGCAGTCAGATCCGTGGATCGA
ACCTCTCTTCACATTGTAGACTTTTTAGTTCAGAACAGTGGGAACCTGGATAAACAGACAGGGAAAGGCAGCACAGCCCTGCACTACTGC
TGCCTGACCGACAATGCCGAGTGCCTCAAGTTGCTCCTGCGGGGGAAGGCCTCCATCGAGATAGCAAACGAGTCAGGAGAGACTCCGCTG
GACATTGCCAAGCGCCTCAAGCACGAGCACTGTGAGGAGCTGCTGACCCAAGCCTTATCTGGAAGATTTAATTCTCACGTTCACGTTGAA
TATGAATGGCGACTACTCCACGAAGACCTGGATGAAAGTGATGACGACATGGATGAGAAATTGCAGCCCAGTCCCAACCGGCGGGAAGAC
CGGCCCATCAGCTTCTACCAGCTGGGCTCCAACCAGCTTCAGTCTAACGCTGTATCTTTGGCCAGAGATGCTGCAAACCTTGCCAAGGAG
AAGCAGAGGGCTTTCATGCCCAGCATCTTGCAGAATGAGACTTACGGAGCCCTCCTGAGTGGCAGCCCACCTCCCGCCCAGCCTGCAGCC
CCCAGCACCACCAGCGCCCCCCCGCTTCCTCCACGGAATGTTGGCAAAGTTCAGACAGCCTCCTCTGCTAACACCCTGTGGAAGACAAAC
TCTGTAAGTGTGGACGGTGGAAGCCGGCAGCGATCTTCGTCAGATCCGCCAGCTGTCCATCCACCGCTGCCCCCTCTTCGCGTGACATCT
ACCAATCCCCTGACCCCCACGCCGCCCCCACCCGTTGCCAAGACGCCCAGCGTAATGGAAGCCTTGAGCCAGCCGAGCAAGCCTGCCCCG
CCTGGGATCTCACAGATCAGGCCCCCACCTCTGCCCCCACAGCCGCCCAGCCGCCTCCCGCAGAAGAAGCCTGCGCCGGGGGCTGACAAG
TCCACCCCACTGACCAACAAAGGCCAACCGAGAGGACCTGTGGATCTCTCTGCAACGGAAGCTCTGGGTCCTCTGTCCAATGCTATGGTC
CTGCAGCCCCCTGCACCCATGCCTAGGAAGTCGCAGGCAACCAAGTTGAAGCCTAAGCGGGTGAAAGCGCTCTATAACTGTGTGGCTGAC
AACCCCGATGAGCTCACCTTCTCCGAGGGGGATGTGATCATCGTGGACGGGGAGGAGGACCAGGAGTGGTGGATTGGCCACATTGATGGA
GATCCTGGTCGCAAAGGCGCATTCCCGGTGTCATTTGTGCACTTTATCGCTGACTGAATTGCTACTGAACAAAAGCATTAACAGTTATGT
TCCTGTTTCGTTATTGGTACCAAAACTCTTGCCAGATAACCAGTTTCATGAACTGTTTGTATGGCAGCCCATGTTCTCTAATGCCACTGC
TCTGTTTTAAAAACTCAGAGGCAATTTTTACATATCAGTAATTGTTTTTATAATTTGTGGTTTTCATGAAACATTGCTATGCATTTATTA
GGAAAAACTGAATTTCCCAACAGGTGAACTGAAAAGTTATTTTAACTATTATACATAATCAAGATCCTGCCTCTACGGAATTAGCTAAAC
CTAAAAATGTTTGCATTAATGAATAAATTCTTCCTGCATTCCTTGGCCCAGTTCTGGAGTTGGTGACCTTTATCACAATTATTATTTTAG
GCGGCCAGTGAACTGCTGCTTCAGAAGTCCATAGCCCAGCTCTGAACTTTCTCGATAAAATGCCATCAGTTCACCTTTAAAGACACACAT
TCCTTTGAAATCCACCCAGTGTTTAAAAAGCAACTTGGAAATTTACACATTAGCATTGTACTTTCTAGCCCTAATTTGTGAGGTTGCAGC
TATCATTATATTCTGCATGTATGTATAACCTGTTGTGAACAATCATACTTAACAAAACTACTGATGGTTTATGACAACGTAGGGTAACTA
CAGTTCATTCTGTTCCAGGTTATATAAAACTGCATTTCCTGAATTTGGTTAAAAACTAAGGATGATGGATTGCAAAACAGTTCTTTTAAA
TTAGTTTATATGCTTTAGGTGTTTTGGAATTTGCCTTCTTGAACTTCCTGAGTCACACAGAAAGCAACTGTACACAGTAGAATTCTGTGG
CGCAGACCATGCTGTATTAACACATCACTTGCTGTTTCCTACTGAGTGTACCACTGCCTTCCCTTCTAGCCCAGGAGAATGTTTACTCAG
TTTAGTGTCTTGTATTTCTATAATACTCCAACAGGAATGGTAGTCACACTGTCTTGAAATTGAATCTGTCCATCTGTTTATAATCAAGAA
CATATCAGAAATATATAGGTCCCAGGTAATACTCCCAAACATCCCACTTTTTACTGTTTCAGGCCATCATATCATTCTTAAGCTACTTGG
GGTGGTAGTAGAGGATTAGGTTGTCTATTATAAAACCAAAACTCATTCGTTTAATGAACTTGACTGTCATACCTCTATTTAGTAATTGCG
AGGGTAAGATTCATAGTAGGAATATTGGAAATTTTGGCACTCTGAGAATAAATAGGCATATGATACCCACTTGGACTTTTAACAAAAGTA
AAGGAATAAATTTGCATATAGGCTTGGAAAGTGAGGCAGCAATGCTGTTAACTGCATTTGTTGTGATGGTGCATTTGATTGAAGCAGCTT
GTCTTTATTATGCAAGACTGTGTAGAGTTTTTTTTTTTTTTGGCATTGTACTTTTTGTTTTTGTTATAAAGGAAGACAGAACAAACTGGA
ATGTTTTATGATGTTGTATAGCAATCGCTTTTTACCTTTCAAAGTTCCGGGTAAAAATGTGTTATATCTGTAGTTTTTTGTTTTTGTTTT
TTTTTAAAGCACTACATCTGTTTTCACTAATTGTTAATTTCTGTTTGAACCCTTCATTTAATTTTCTCATAGATTTAAGTAAACAGATGT
ATTTTGCACAGTGCACTTATGTCTATTTTAACAATCCTCCTGCATCTGTATTTTATAGTCAGCCTTTTGACCACCTGGTGCCAGCTATAT
AAGGAATAAAGTTGATTCATATCAACATTAGAACTCCAGTCCCAAACTAATCTGTCAGGTTCACTGGTACATAAATACCTAGGAAATATT
TTTCCAGTCTACAATTTGGTGCTATTGTGCAGTAACTAATAGTACTCTTACCAGAGGAGAAATTATATTAACGACCCTGCTAATATCCTT
TCTTAGTTATTTGCTCCTTGCAAATTAAAAAAGCAACTAAGAGAAAGAAAAACATTGTAGATATCTATTTATATTTAAAGTTTATGTTTC
ATGAACTGCAGCTGCAGGATTCTGGCATTTTGCATGCCATTCTCCATCAGATCTGGGATGATGGCTCAGAACATGTACACAGACTAAGAG
TAACTGTGTGATCTGTTAAGGGGTGGATAACATAATATGCAGCTTAGGATGCTATTTTGAGATGTATGATATTCAGTTCATTCACCTGAT
TACTTTGGTTGCAGCACAACTGTATATATTGTATAACCGAAATTGATTATTTTCATTGTCCTTAATGCAGTGATTTATAATTAGAGCATG

>67000_67000_1_POLR2A-ASAP2_POLR2A_chr17_7388176_ENST00000322644_ASAP2_chr2_9419446_ENST00000281419_length(amino acids)=1005AA_BP=36
MRLRSAPASAMHGGGPPSGDSACPLRTIKRVQFGVLSPDELALDVDRMVLYKMKKSVKAINSSGLAHVENEEQYTQALEKFGGNCVCRDD
PDLGSAFLKFSVFTKELTALFKNLIQNMNNIISFPLDSLLKGDLKGVKGDLKKPFDKAWKDYETKITKIEKEKKEHAKLHGMIRTEISGA
EIAEEMEKERRFFQLQMCEYLLKVNEIKIKKGVDLLQNLIKYFHAQCNFFQDGLKAVESLKPSIETLSTDLHTIKQAQDEERRQLIQLRD
ILKSALQVEQKEDSQIRQSTAYSLHQPQGNKEHGTERNGSLYKKSDGIRKVWQKRKCSVKNGFLTISHGTANRPPAKLNLLTCQVKTNPE
EKKCFDLISHDRTYHFQAEDEQECQIWMSVLQNSKEEALNNAFKGDDNTGENNIVQELTKEIISEVQRMTGNDVCCDCGAPDPTWLSTNL
GILTCIECSGIHRELGVHYSRMQSLTLDVLGTSELLLAKNIGNAGFNEIMECCLPAEDSVKPNPGSDMNARKDYITAKYIERRYARKKHA
DNAAKLHSLCEAVKTRDIFGLLQAYADGVDLTEKIPLANGHEPDETALHLAVRSVDRTSLHIVDFLVQNSGNLDKQTGKGSTALHYCCLT
DNAECLKLLLRGKASIEIANESGETPLDIAKRLKHEHCEELLTQALSGRFNSHVHVEYEWRLLHEDLDESDDDMDEKLQPSPNRREDRPI
SFYQLGSNQLQSNAVSLARDAANLAKEKQRAFMPSILQNETYGALLSGSPPPAQPAAPSTTSAPPLPPRNVGKVQTASSANTLWKTNSVS
VDGGSRQRSSSDPPAVHPPLPPLRVTSTNPLTPTPPPPVAKTPSVMEALSQPSKPAPPGISQIRPPPLPPQPPSRLPQKKPAPGADKSTP
LTNKGQPRGPVDLSATEALGPLSNAMVLQPPAPMPRKSQATKLKPKRVKALYNCVADNPDELTFSEGDVIIVDGEEDQEWWIGHIDGDPG

--------------------------------------------------------------
>67000_67000_2_POLR2A-ASAP2_POLR2A_chr17_7388176_ENST00000322644_ASAP2_chr2_9419446_ENST00000315273_length(transcript)=5608nt_BP=492nt
GCTCAGAAGCGCCGAGAGCGCGGCCGGGACGGTTGGAGAAGAAGGCGGCTCCCGGAAGGGGGAGAGACAAACTGCCGTAACCTCTGCCGT
TCAGGAACCCGGTTACTTATTTATTCGTTACCCTTTTTCTTCTTCCTCCCCCAAAAACCTTTTCCTTTTCCCTTCTTTTTTTTTCCTTTT
TGGGAGCTGAAAAATTTCCGGTAAGGGAAAGAAGGGCTCCTTTCGCTCCTTATTTCCCCGCCTCCTTCCCTCCCCCACCTTCCCCTCCTC
CGGCTTTTTCCTCCCAACTCGGGGAGGTCCTTCCCGGTGGCCGCCCTGACGAGGTCTGAGCACCTAGGCGGAGGCGGCGCAGGCTTTTTG
TAGTGAGGTTTGCGCCTGCGCAGCGCGCCTGCCTCCGCCATGCACGGGGGTGGCCCCCCCTCGGGGGACAGCGCATGCCCGCTGCGCACC
ATCAAGAGAGTCCAGTTCGGAGTCCTGAGTCCGGATGAACTGGCTTTGGACGTGGACCGGATGGTTCTTTACAAAATGAAGAAATCCGTG
AAAGCAATCAACAGCTCTGGGCTGGCTCACGTGGAAAATGAAGAGCAGTACACCCAGGCTCTGGAGAAGTTTGGCGGCAACTGTGTATGC
AGAGATGACCCAGATTTAGGAAGTGCGTTCCTGAAGTTCTCAGTGTTTACAAAGGAGTTGACAGCACTTTTCAAAAACCTGATTCAGAAT
ATGAACAACATAATCTCCTTCCCTTTGGACAGTTTGCTGAAGGGGGACCTGAAAGGAGTGAAAGGGGATCTGAAAAAGCCTTTTGATAAA
GCTTGGAAGGACTATGAAACAAAAATAACCAAGATAGAAAAGGAGAAAAAGGAACACGCCAAGCTCCATGGGATGATTCGGACTGAAATA
AGCGGAGCGGAAATTGCCGAAGAGATGGAAAAGGAGAGGCGCTTCTTCCAGCTACAGATGTGCGAGTATCTGCTGAAGGTCAACGAAATC
AAGATTAAAAAGGGAGTAGATTTACTTCAGAATCTGATCAAATACTTTCATGCCCAATGCAATTTTTTTCAGGATGGACTCAAAGCCGTG
GAAAGCCTCAAACCTTCCATTGAAACGCTGTCTACGGATCTTCACACGATCAAACAGGCCCAGGATGAAGAAAGAAGGCAGTTGATACAG
CTTCGAGATATTTTGAAATCCGCATTGCAGGTTGAACAGAAAGAGGACTCCCAAATTCGTCAGAGCACAGCTTATAGCTTACATCAGCCT
CAGGGAAACAAGGAACATGGGACCGAGCGGAACGGCAGCCTCTACAAGAAGAGTGACGGGATCCGAAAAGTGTGGCAGAAAAGGAAATGT
TCAGTTAAAAATGGTTTTCTGACCATATCCCATGGTACCGCTAACCGGCCTCCTGCAAAGCTCAACCTGCTAACCTGCCAGGTGAAGACC
AACCCTGAGGAGAAGAAGTGCTTTGACCTCATTTCACATGACAGAACTTACCACTTTCAAGCTGAAGATGAACAGGAATGTCAAATATGG
ATGTCTGTGCTGCAAAATAGCAAAGAAGAAGCTTTAAACAATGCATTTAAGGGGGATGACAATACTGGAGAAAATAACATCGTCCAAGAA
CTGACAAAGGAGATCATCTCAGAAGTGCAGAGGATGACGGGCAATGACGTCTGCTGTGACTGTGGGGCGCCAGATCCTACATGGCTTTCC
ACCAACCTGGGCATCCTGACCTGCATCGAGTGTTCCGGAATCCACCGAGAGCTGGGGGTTCATTATTCCAGGATGCAGTCCCTGACCTTA
GATGTACTGGGAACATCTGAGCTGCTGCTCGCCAAGAATATTGGGAATGCAGGCTTTAATGAGATCATGGAATGTTGCCTACCAGCTGAG
GACTCAGTCAAACCCAACCCAGGCAGCGACATGAATGCAAGAAAGGACTACATCACAGCCAAGTACATCGAGAGGAGATACGCAAGGAAG
AAGCACGCGGATAACGCGGCGAAGCTTCACAGTCTTTGCGAGGCCGTCAAAACGAGAGATATTTTTGGATTGCTCCAAGCTTATGCTGAT
GGTGTGGATCTTACGGAAAAAATCCCACTGGCCAACGGACATGAGCCGGATGAAACGGCCCTCCACCTTGCAGTCAGATCCGTGGATCGA
ACCTCTCTTCACATTGTAGACTTTTTAGTTCAGAACAGTGGGAACCTGGATAAACAGACAGGGAAAGGCAGCACAGCCCTGCACTACTGC
TGCCTGACCGACAATGCCGAGTGCCTCAAGTTGCTCCTGCGGGGGAAGGCCTCCATCGAGATAGCAAACGAGTCAGGAGAGACTCCGCTG
GACATTGCCAAGCGCCTCAAGCACGAGCACTGTGAGGAGCTGCTGACCCAAGCCTTATCTGGAAGATTTAATTCTCACGTTCACGTTGAA
TATGAATGGCGACTACTCCACGAAGACCTGGATGAAAGTGATGACGACATGGATGAGAAATTGCAGCCCAGTCCCAACCGGCGGGAAGAC
CGGCCCATCAGCTTCTACCAGCTGGGCTCCAACCAGCTTCAGTCTAACGCTGTATCTTTGGCCAGAGATGCTGCAAACCTTGCCAAGGAG
AAGCAGAGGGCTTTCATGCCCAGCATCTTGCAGAATGAGACTTACGGAGCCCTCCTGAGTGGCAGCCCACCTCCCGCCCAGCCTGCAGCC
CCCAGCACCACCAGCGCCCCCCCGCTTCCTCCACGGAATGTTGGCAAAGATCCCCTGACCCCCACGCCGCCCCCACCCGTTGCCAAGACG
CCCAGCGTAATGGAAGCCTTGAGCCAGCCGAGCAAGCCTGCCCCGCCTGGGATCTCACAGATCAGGCCCCCACCTCTGCCCCCACAGCCG
CCCAGCCGCCTCCCGCAGAAGAAGCCTGCGCCGGGGGCTGACAAGTCCACCCCACTGACCAACAAAGGCCAACCGAGAGGACCTGTGGAT
CTCTCTGCAACGGAAGCTCTGGGTCCTCTGTCCAATGCTATGGTCCTGCAGCCCCCTGCACCCATGCCTAGGAAGTCGCAGGCAACCAAG
TTGAAGCCTAAGCGGGTGAAAGCGCTCTATAACTGTGTGGCTGACAACCCCGATGAGCTCACCTTCTCCGAGGGGGATGTGATCATCGTG
GACGGGGAGGAGGACCAGGAGTGGTGGATTGGCCACATTGATGGAGATCCTGGTCGCAAAGGCGCATTCCCGGTGTCATTTGTGCACTTT
ATCGCTGACTGAATTGCTACTGAACAAAAGCATTAACAGTTATGTTCCTGTTTCGTTATTGGTACCAAAACTCTTGCCAGATAACCAGTT
TCATGAACTGTTTGTATGGCAGCCCATGTTCTCTAATGCCACTGCTCTGTTTTAAAAACTCAGAGGCAATTTTTACATATCAGTAATTGT
TTTTATAATTTGTGGTTTTCATGAAACATTGCTATGCATTTATTAGGAAAAACTGAATTTCCCAACAGGTGAACTGAAAAGTTATTTTAA
CTATTATACATAATCAAGATCCTGCCTCTACGGAATTAGCTAAACCTAAAAATGTTTGCATTAATGAATAAATTCTTCCTGCATTCCTTG
GCCCAGTTCTGGAGTTGGTGACCTTTATCACAATTATTATTTTAGGCGGCCAGTGAACTGCTGCTTCAGAAGTCCATAGCCCAGCTCTGA
ACTTTCTCGATAAAATGCCATCAGTTCACCTTTAAAGACACACATTCCTTTGAAATCCACCCAGTGTTTAAAAAGCAACTTGGAAATTTA
CACATTAGCATTGTACTTTCTAGCCCTAATTTGTGAGGTTGCAGCTATCATTATATTCTGCATGTATGTATAACCTGTTGTGAACAATCA
TACTTAACAAAACTACTGATGGTTTATGACAACGTAGGGTAACTACAGTTCATTCTGTTCCAGGTTATATAAAACTGCATTTCCTGAATT
TGGTTAAAAACTAAGGATGATGGATTGCAAAACAGTTCTTTTAAATTAGTTTATATGCTTTAGGTGTTTTGGAATTTGCCTTCTTGAACT
TCCTGAGTCACACAGAAAGCAACTGTACACAGTAGAATTCTGTGGCGCAGACCATGCTGTATTAACACATCACTTGCTGTTTCCTACTGA
GTGTACCACTGCCTTCCCTTCTAGCCCAGGAGAATGTTTACTCAGTTTAGTGTCTTGTATTTCTATAATACTCCAACAGGAATGGTAGTC
ACACTGTCTTGAAATTGAATCTGTCCATCTGTTTATAATCAAGAACATATCAGAAATATATAGGTCCCAGGTAATACTCCCAAACATCCC
ACTTTTTACTGTTTCAGGCCATCATATCATTCTTAAGCTACTTGGGGTGGTAGTAGAGGATTAGGTTGTCTATTATAAAACCAAAACTCA
TTCGTTTAATGAACTTGACTGTCATACCTCTATTTAGTAATTGCGAGGGTAAGATTCATAGTAGGAATATTGGAAATTTTGGCACTCTGA
GAATAAATAGGCATATGATACCCACTTGGACTTTTAACAAAAGTAAAGGAATAAATTTGCATATAGGCTTGGAAAGTGAGGCAGCAATGC
TGTTAACTGCATTTGTTGTGATGGTGCATTTGATTGAAGCAGCTTGTCTTTATTATGCAAGACTGTGTAGAGTTTTTTTTTTTTTTGGCA
TTGTACTTTTTGTTTTTGTTATAAAGGAAGACAGAACAAACTGGAATGTTTTATGATGTTGTATAGCAATCGCTTTTTACCTTTCAAAGT
TCCGGGTAAAAATGTGTTATATCTGTAGTTTTTTGTTTTTGTTTTTTTTTAAAGCACTACATCTGTTTTCACTAATTGTTAATTTCTGTT
TGAACCCTTCATTTAATTTTCTCATAGATTTAAGTAAACAGATGTATTTTGCACAGTGCACTTATGTCTATTTTAACAATCCTCCTGCAT
CTGTATTTTATAGTCAGCCTTTTGACCACCTGGTGCCAGCTATATAAGGAATAAAGTTGATTCATATCAACATTAGAACTCCAGTCCCAA
ACTAATCTGTCAGGTTCACTGGTACATAAATACCTAGGAAATATTTTTCCAGTCTACAATTTGGTGCTATTGTGCAGTAACTAATAGTAC
TCTTACCAGAGGAGAAATTATATTAACGACCCTGCTAATATCCTTTCTTAGTTATTTGCTCCTTGCAAATTAAAAAAGCAACTAAGAGAA
AGAAAAACATTGTAGATATCTATTTATATTTAAAGTTTATGTTTCATGAACTGCAGCTGCAGGATTCTGGCATTTTGCATGCCATTCTCC
ATCAGATCTGGGATGATGGCTCAGAACATGTACACAGACTAAGAGTAACTGTGTGATCTGTTAAGGGGTGGATAACATAATATGCAGCTT
AGGATGCTATTTTGAGATGTATGATATTCAGTTCATTCACCTGATTACTTTGGTTGCAGCACAACTGTATATATTGTATAACCGAAATTG
ATTATTTTCATTGTCCTTAATGCAGTGATTTATAATTAGAGCATGTTTAATAAGTTTACTCTTCTTGTTAACTAGTCATTTGACTGGAAA

>67000_67000_2_POLR2A-ASAP2_POLR2A_chr17_7388176_ENST00000322644_ASAP2_chr2_9419446_ENST00000315273_length(amino acids)=960AA_BP=36
MRLRSAPASAMHGGGPPSGDSACPLRTIKRVQFGVLSPDELALDVDRMVLYKMKKSVKAINSSGLAHVENEEQYTQALEKFGGNCVCRDD
PDLGSAFLKFSVFTKELTALFKNLIQNMNNIISFPLDSLLKGDLKGVKGDLKKPFDKAWKDYETKITKIEKEKKEHAKLHGMIRTEISGA
EIAEEMEKERRFFQLQMCEYLLKVNEIKIKKGVDLLQNLIKYFHAQCNFFQDGLKAVESLKPSIETLSTDLHTIKQAQDEERRQLIQLRD
ILKSALQVEQKEDSQIRQSTAYSLHQPQGNKEHGTERNGSLYKKSDGIRKVWQKRKCSVKNGFLTISHGTANRPPAKLNLLTCQVKTNPE
EKKCFDLISHDRTYHFQAEDEQECQIWMSVLQNSKEEALNNAFKGDDNTGENNIVQELTKEIISEVQRMTGNDVCCDCGAPDPTWLSTNL
GILTCIECSGIHRELGVHYSRMQSLTLDVLGTSELLLAKNIGNAGFNEIMECCLPAEDSVKPNPGSDMNARKDYITAKYIERRYARKKHA
DNAAKLHSLCEAVKTRDIFGLLQAYADGVDLTEKIPLANGHEPDETALHLAVRSVDRTSLHIVDFLVQNSGNLDKQTGKGSTALHYCCLT
DNAECLKLLLRGKASIEIANESGETPLDIAKRLKHEHCEELLTQALSGRFNSHVHVEYEWRLLHEDLDESDDDMDEKLQPSPNRREDRPI
SFYQLGSNQLQSNAVSLARDAANLAKEKQRAFMPSILQNETYGALLSGSPPPAQPAAPSTTSAPPLPPRNVGKDPLTPTPPPPVAKTPSV
MEALSQPSKPAPPGISQIRPPPLPPQPPSRLPQKKPAPGADKSTPLTNKGQPRGPVDLSATEALGPLSNAMVLQPPAPMPRKSQATKLKP

--------------------------------------------------------------
>67000_67000_3_POLR2A-ASAP2_POLR2A_chr17_7388176_ENST00000572844_ASAP2_chr2_9419446_ENST00000281419_length(transcript)=5484nt_BP=238nt
CCACCTTCCCCTCCTCCGGCTTTTTCCTCCCAACTCGGGGAGGTCCTTCCCGGTGGCCGCCCTGACGAGGTCTGAGCACCTAGGCGGAGG
CGGCGCAGGCTTTTTGTAGTGAGGTTTGCGCCTGCGCAGCGCGCCTGCCTCCGCCATGCACGGGGGTGGCCCCCCCTCGGGGGACAGCGC
ATGCCCGCTGCGCACCATCAAGAGAGTCCAGTTCGGAGTCCTGAGTCCGGATGAACTGGCTTTGGACGTGGACCGGATGGTTCTTTACAA
AATGAAGAAATCCGTGAAAGCAATCAACAGCTCTGGGCTGGCTCACGTGGAAAATGAAGAGCAGTACACCCAGGCTCTGGAGAAGTTTGG
CGGCAACTGTGTATGCAGAGATGACCCAGATTTAGGAAGTGCGTTCCTGAAGTTCTCAGTGTTTACAAAGGAGTTGACAGCACTTTTCAA
AAACCTGATTCAGAATATGAACAACATAATCTCCTTCCCTTTGGACAGTTTGCTGAAGGGGGACCTGAAAGGAGTGAAAGGGGATCTGAA
AAAGCCTTTTGATAAAGCTTGGAAGGACTATGAAACAAAAATAACCAAGATAGAAAAGGAGAAAAAGGAACACGCCAAGCTCCATGGGAT
GATTCGGACTGAAATAAGCGGAGCGGAAATTGCCGAAGAGATGGAAAAGGAGAGGCGCTTCTTCCAGCTACAGATGTGCGAGTATCTGCT
GAAGGTCAACGAAATCAAGATTAAAAAGGGAGTAGATTTACTTCAGAATCTGATCAAATACTTTCATGCCCAATGCAATTTTTTTCAGGA
TGGACTCAAAGCCGTGGAAAGCCTCAAACCTTCCATTGAAACGCTGTCTACGGATCTTCACACGATCAAACAGGCCCAGGATGAAGAAAG
AAGGCAGTTGATACAGCTTCGAGATATTTTGAAATCCGCATTGCAGGTTGAACAGAAAGAGGACTCCCAAATTCGTCAGAGCACAGCTTA
TAGCTTACATCAGCCTCAGGGAAACAAGGAACATGGGACCGAGCGGAACGGCAGCCTCTACAAGAAGAGTGACGGGATCCGAAAAGTGTG
GCAGAAAAGGAAATGTTCAGTTAAAAATGGTTTTCTGACCATATCCCATGGTACCGCTAACCGGCCTCCTGCAAAGCTCAACCTGCTAAC
CTGCCAGGTGAAGACCAACCCTGAGGAGAAGAAGTGCTTTGACCTCATTTCACATGACAGAACTTACCACTTTCAAGCTGAAGATGAACA
GGAATGTCAAATATGGATGTCTGTGCTGCAAAATAGCAAAGAAGAAGCTTTAAACAATGCATTTAAGGGGGATGACAATACTGGAGAAAA
TAACATCGTCCAAGAACTGACAAAGGAGATCATCTCAGAAGTGCAGAGGATGACGGGCAATGACGTCTGCTGTGACTGTGGGGCGCCAGA
TCCTACATGGCTTTCCACCAACCTGGGCATCCTGACCTGCATCGAGTGTTCCGGAATCCACCGAGAGCTGGGGGTTCATTATTCCAGGAT
GCAGTCCCTGACCTTAGATGTACTGGGAACATCTGAGCTGCTGCTCGCCAAGAATATTGGGAATGCAGGCTTTAATGAGATCATGGAATG
TTGCCTACCAGCTGAGGACTCAGTCAAACCCAACCCAGGCAGCGACATGAATGCAAGAAAGGACTACATCACAGCCAAGTACATCGAGAG
GAGATACGCAAGGAAGAAGCACGCGGATAACGCGGCGAAGCTTCACAGTCTTTGCGAGGCCGTCAAAACGAGAGATATTTTTGGATTGCT
CCAAGCTTATGCTGATGGTGTGGATCTTACGGAAAAAATCCCACTGGCCAACGGACATGAGCCGGATGAAACGGCCCTCCACCTTGCAGT
CAGATCCGTGGATCGAACCTCTCTTCACATTGTAGACTTTTTAGTTCAGAACAGTGGGAACCTGGATAAACAGACAGGGAAAGGCAGCAC
AGCCCTGCACTACTGCTGCCTGACCGACAATGCCGAGTGCCTCAAGTTGCTCCTGCGGGGGAAGGCCTCCATCGAGATAGCAAACGAGTC
AGGAGAGACTCCGCTGGACATTGCCAAGCGCCTCAAGCACGAGCACTGTGAGGAGCTGCTGACCCAAGCCTTATCTGGAAGATTTAATTC
TCACGTTCACGTTGAATATGAATGGCGACTACTCCACGAAGACCTGGATGAAAGTGATGACGACATGGATGAGAAATTGCAGCCCAGTCC
CAACCGGCGGGAAGACCGGCCCATCAGCTTCTACCAGCTGGGCTCCAACCAGCTTCAGTCTAACGCTGTATCTTTGGCCAGAGATGCTGC
AAACCTTGCCAAGGAGAAGCAGAGGGCTTTCATGCCCAGCATCTTGCAGAATGAGACTTACGGAGCCCTCCTGAGTGGCAGCCCACCTCC
CGCCCAGCCTGCAGCCCCCAGCACCACCAGCGCCCCCCCGCTTCCTCCACGGAATGTTGGCAAAGTTCAGACAGCCTCCTCTGCTAACAC
CCTGTGGAAGACAAACTCTGTAAGTGTGGACGGTGGAAGCCGGCAGCGATCTTCGTCAGATCCGCCAGCTGTCCATCCACCGCTGCCCCC
TCTTCGCGTGACATCTACCAATCCCCTGACCCCCACGCCGCCCCCACCCGTTGCCAAGACGCCCAGCGTAATGGAAGCCTTGAGCCAGCC
GAGCAAGCCTGCCCCGCCTGGGATCTCACAGATCAGGCCCCCACCTCTGCCCCCACAGCCGCCCAGCCGCCTCCCGCAGAAGAAGCCTGC
GCCGGGGGCTGACAAGTCCACCCCACTGACCAACAAAGGCCAACCGAGAGGACCTGTGGATCTCTCTGCAACGGAAGCTCTGGGTCCTCT
GTCCAATGCTATGGTCCTGCAGCCCCCTGCACCCATGCCTAGGAAGTCGCAGGCAACCAAGTTGAAGCCTAAGCGGGTGAAAGCGCTCTA
TAACTGTGTGGCTGACAACCCCGATGAGCTCACCTTCTCCGAGGGGGATGTGATCATCGTGGACGGGGAGGAGGACCAGGAGTGGTGGAT
TGGCCACATTGATGGAGATCCTGGTCGCAAAGGCGCATTCCCGGTGTCATTTGTGCACTTTATCGCTGACTGAATTGCTACTGAACAAAA
GCATTAACAGTTATGTTCCTGTTTCGTTATTGGTACCAAAACTCTTGCCAGATAACCAGTTTCATGAACTGTTTGTATGGCAGCCCATGT
TCTCTAATGCCACTGCTCTGTTTTAAAAACTCAGAGGCAATTTTTACATATCAGTAATTGTTTTTATAATTTGTGGTTTTCATGAAACAT
TGCTATGCATTTATTAGGAAAAACTGAATTTCCCAACAGGTGAACTGAAAAGTTATTTTAACTATTATACATAATCAAGATCCTGCCTCT
ACGGAATTAGCTAAACCTAAAAATGTTTGCATTAATGAATAAATTCTTCCTGCATTCCTTGGCCCAGTTCTGGAGTTGGTGACCTTTATC
ACAATTATTATTTTAGGCGGCCAGTGAACTGCTGCTTCAGAAGTCCATAGCCCAGCTCTGAACTTTCTCGATAAAATGCCATCAGTTCAC
CTTTAAAGACACACATTCCTTTGAAATCCACCCAGTGTTTAAAAAGCAACTTGGAAATTTACACATTAGCATTGTACTTTCTAGCCCTAA
TTTGTGAGGTTGCAGCTATCATTATATTCTGCATGTATGTATAACCTGTTGTGAACAATCATACTTAACAAAACTACTGATGGTTTATGA
CAACGTAGGGTAACTACAGTTCATTCTGTTCCAGGTTATATAAAACTGCATTTCCTGAATTTGGTTAAAAACTAAGGATGATGGATTGCA
AAACAGTTCTTTTAAATTAGTTTATATGCTTTAGGTGTTTTGGAATTTGCCTTCTTGAACTTCCTGAGTCACACAGAAAGCAACTGTACA
CAGTAGAATTCTGTGGCGCAGACCATGCTGTATTAACACATCACTTGCTGTTTCCTACTGAGTGTACCACTGCCTTCCCTTCTAGCCCAG
GAGAATGTTTACTCAGTTTAGTGTCTTGTATTTCTATAATACTCCAACAGGAATGGTAGTCACACTGTCTTGAAATTGAATCTGTCCATC
TGTTTATAATCAAGAACATATCAGAAATATATAGGTCCCAGGTAATACTCCCAAACATCCCACTTTTTACTGTTTCAGGCCATCATATCA
TTCTTAAGCTACTTGGGGTGGTAGTAGAGGATTAGGTTGTCTATTATAAAACCAAAACTCATTCGTTTAATGAACTTGACTGTCATACCT
CTATTTAGTAATTGCGAGGGTAAGATTCATAGTAGGAATATTGGAAATTTTGGCACTCTGAGAATAAATAGGCATATGATACCCACTTGG
ACTTTTAACAAAAGTAAAGGAATAAATTTGCATATAGGCTTGGAAAGTGAGGCAGCAATGCTGTTAACTGCATTTGTTGTGATGGTGCAT
TTGATTGAAGCAGCTTGTCTTTATTATGCAAGACTGTGTAGAGTTTTTTTTTTTTTTGGCATTGTACTTTTTGTTTTTGTTATAAAGGAA
GACAGAACAAACTGGAATGTTTTATGATGTTGTATAGCAATCGCTTTTTACCTTTCAAAGTTCCGGGTAAAAATGTGTTATATCTGTAGT
TTTTTGTTTTTGTTTTTTTTTAAAGCACTACATCTGTTTTCACTAATTGTTAATTTCTGTTTGAACCCTTCATTTAATTTTCTCATAGAT
TTAAGTAAACAGATGTATTTTGCACAGTGCACTTATGTCTATTTTAACAATCCTCCTGCATCTGTATTTTATAGTCAGCCTTTTGACCAC
CTGGTGCCAGCTATATAAGGAATAAAGTTGATTCATATCAACATTAGAACTCCAGTCCCAAACTAATCTGTCAGGTTCACTGGTACATAA
ATACCTAGGAAATATTTTTCCAGTCTACAATTTGGTGCTATTGTGCAGTAACTAATAGTACTCTTACCAGAGGAGAAATTATATTAACGA
CCCTGCTAATATCCTTTCTTAGTTATTTGCTCCTTGCAAATTAAAAAAGCAACTAAGAGAAAGAAAAACATTGTAGATATCTATTTATAT
TTAAAGTTTATGTTTCATGAACTGCAGCTGCAGGATTCTGGCATTTTGCATGCCATTCTCCATCAGATCTGGGATGATGGCTCAGAACAT
GTACACAGACTAAGAGTAACTGTGTGATCTGTTAAGGGGTGGATAACATAATATGCAGCTTAGGATGCTATTTTGAGATGTATGATATTC
AGTTCATTCACCTGATTACTTTGGTTGCAGCACAACTGTATATATTGTATAACCGAAATTGATTATTTTCATTGTCCTTAATGCAGTGAT

>67000_67000_3_POLR2A-ASAP2_POLR2A_chr17_7388176_ENST00000572844_ASAP2_chr2_9419446_ENST00000281419_length(amino acids)=1005AA_BP=36
MRLRSAPASAMHGGGPPSGDSACPLRTIKRVQFGVLSPDELALDVDRMVLYKMKKSVKAINSSGLAHVENEEQYTQALEKFGGNCVCRDD
PDLGSAFLKFSVFTKELTALFKNLIQNMNNIISFPLDSLLKGDLKGVKGDLKKPFDKAWKDYETKITKIEKEKKEHAKLHGMIRTEISGA
EIAEEMEKERRFFQLQMCEYLLKVNEIKIKKGVDLLQNLIKYFHAQCNFFQDGLKAVESLKPSIETLSTDLHTIKQAQDEERRQLIQLRD
ILKSALQVEQKEDSQIRQSTAYSLHQPQGNKEHGTERNGSLYKKSDGIRKVWQKRKCSVKNGFLTISHGTANRPPAKLNLLTCQVKTNPE
EKKCFDLISHDRTYHFQAEDEQECQIWMSVLQNSKEEALNNAFKGDDNTGENNIVQELTKEIISEVQRMTGNDVCCDCGAPDPTWLSTNL
GILTCIECSGIHRELGVHYSRMQSLTLDVLGTSELLLAKNIGNAGFNEIMECCLPAEDSVKPNPGSDMNARKDYITAKYIERRYARKKHA
DNAAKLHSLCEAVKTRDIFGLLQAYADGVDLTEKIPLANGHEPDETALHLAVRSVDRTSLHIVDFLVQNSGNLDKQTGKGSTALHYCCLT
DNAECLKLLLRGKASIEIANESGETPLDIAKRLKHEHCEELLTQALSGRFNSHVHVEYEWRLLHEDLDESDDDMDEKLQPSPNRREDRPI
SFYQLGSNQLQSNAVSLARDAANLAKEKQRAFMPSILQNETYGALLSGSPPPAQPAAPSTTSAPPLPPRNVGKVQTASSANTLWKTNSVS
VDGGSRQRSSSDPPAVHPPLPPLRVTSTNPLTPTPPPPVAKTPSVMEALSQPSKPAPPGISQIRPPPLPPQPPSRLPQKKPAPGADKSTP
LTNKGQPRGPVDLSATEALGPLSNAMVLQPPAPMPRKSQATKLKPKRVKALYNCVADNPDELTFSEGDVIIVDGEEDQEWWIGHIDGDPG

--------------------------------------------------------------
>67000_67000_4_POLR2A-ASAP2_POLR2A_chr17_7388176_ENST00000572844_ASAP2_chr2_9419446_ENST00000315273_length(transcript)=5354nt_BP=238nt
CCACCTTCCCCTCCTCCGGCTTTTTCCTCCCAACTCGGGGAGGTCCTTCCCGGTGGCCGCCCTGACGAGGTCTGAGCACCTAGGCGGAGG
CGGCGCAGGCTTTTTGTAGTGAGGTTTGCGCCTGCGCAGCGCGCCTGCCTCCGCCATGCACGGGGGTGGCCCCCCCTCGGGGGACAGCGC
ATGCCCGCTGCGCACCATCAAGAGAGTCCAGTTCGGAGTCCTGAGTCCGGATGAACTGGCTTTGGACGTGGACCGGATGGTTCTTTACAA
AATGAAGAAATCCGTGAAAGCAATCAACAGCTCTGGGCTGGCTCACGTGGAAAATGAAGAGCAGTACACCCAGGCTCTGGAGAAGTTTGG
CGGCAACTGTGTATGCAGAGATGACCCAGATTTAGGAAGTGCGTTCCTGAAGTTCTCAGTGTTTACAAAGGAGTTGACAGCACTTTTCAA
AAACCTGATTCAGAATATGAACAACATAATCTCCTTCCCTTTGGACAGTTTGCTGAAGGGGGACCTGAAAGGAGTGAAAGGGGATCTGAA
AAAGCCTTTTGATAAAGCTTGGAAGGACTATGAAACAAAAATAACCAAGATAGAAAAGGAGAAAAAGGAACACGCCAAGCTCCATGGGAT
GATTCGGACTGAAATAAGCGGAGCGGAAATTGCCGAAGAGATGGAAAAGGAGAGGCGCTTCTTCCAGCTACAGATGTGCGAGTATCTGCT
GAAGGTCAACGAAATCAAGATTAAAAAGGGAGTAGATTTACTTCAGAATCTGATCAAATACTTTCATGCCCAATGCAATTTTTTTCAGGA
TGGACTCAAAGCCGTGGAAAGCCTCAAACCTTCCATTGAAACGCTGTCTACGGATCTTCACACGATCAAACAGGCCCAGGATGAAGAAAG
AAGGCAGTTGATACAGCTTCGAGATATTTTGAAATCCGCATTGCAGGTTGAACAGAAAGAGGACTCCCAAATTCGTCAGAGCACAGCTTA
TAGCTTACATCAGCCTCAGGGAAACAAGGAACATGGGACCGAGCGGAACGGCAGCCTCTACAAGAAGAGTGACGGGATCCGAAAAGTGTG
GCAGAAAAGGAAATGTTCAGTTAAAAATGGTTTTCTGACCATATCCCATGGTACCGCTAACCGGCCTCCTGCAAAGCTCAACCTGCTAAC
CTGCCAGGTGAAGACCAACCCTGAGGAGAAGAAGTGCTTTGACCTCATTTCACATGACAGAACTTACCACTTTCAAGCTGAAGATGAACA
GGAATGTCAAATATGGATGTCTGTGCTGCAAAATAGCAAAGAAGAAGCTTTAAACAATGCATTTAAGGGGGATGACAATACTGGAGAAAA
TAACATCGTCCAAGAACTGACAAAGGAGATCATCTCAGAAGTGCAGAGGATGACGGGCAATGACGTCTGCTGTGACTGTGGGGCGCCAGA
TCCTACATGGCTTTCCACCAACCTGGGCATCCTGACCTGCATCGAGTGTTCCGGAATCCACCGAGAGCTGGGGGTTCATTATTCCAGGAT
GCAGTCCCTGACCTTAGATGTACTGGGAACATCTGAGCTGCTGCTCGCCAAGAATATTGGGAATGCAGGCTTTAATGAGATCATGGAATG
TTGCCTACCAGCTGAGGACTCAGTCAAACCCAACCCAGGCAGCGACATGAATGCAAGAAAGGACTACATCACAGCCAAGTACATCGAGAG
GAGATACGCAAGGAAGAAGCACGCGGATAACGCGGCGAAGCTTCACAGTCTTTGCGAGGCCGTCAAAACGAGAGATATTTTTGGATTGCT
CCAAGCTTATGCTGATGGTGTGGATCTTACGGAAAAAATCCCACTGGCCAACGGACATGAGCCGGATGAAACGGCCCTCCACCTTGCAGT
CAGATCCGTGGATCGAACCTCTCTTCACATTGTAGACTTTTTAGTTCAGAACAGTGGGAACCTGGATAAACAGACAGGGAAAGGCAGCAC
AGCCCTGCACTACTGCTGCCTGACCGACAATGCCGAGTGCCTCAAGTTGCTCCTGCGGGGGAAGGCCTCCATCGAGATAGCAAACGAGTC
AGGAGAGACTCCGCTGGACATTGCCAAGCGCCTCAAGCACGAGCACTGTGAGGAGCTGCTGACCCAAGCCTTATCTGGAAGATTTAATTC
TCACGTTCACGTTGAATATGAATGGCGACTACTCCACGAAGACCTGGATGAAAGTGATGACGACATGGATGAGAAATTGCAGCCCAGTCC
CAACCGGCGGGAAGACCGGCCCATCAGCTTCTACCAGCTGGGCTCCAACCAGCTTCAGTCTAACGCTGTATCTTTGGCCAGAGATGCTGC
AAACCTTGCCAAGGAGAAGCAGAGGGCTTTCATGCCCAGCATCTTGCAGAATGAGACTTACGGAGCCCTCCTGAGTGGCAGCCCACCTCC
CGCCCAGCCTGCAGCCCCCAGCACCACCAGCGCCCCCCCGCTTCCTCCACGGAATGTTGGCAAAGATCCCCTGACCCCCACGCCGCCCCC
ACCCGTTGCCAAGACGCCCAGCGTAATGGAAGCCTTGAGCCAGCCGAGCAAGCCTGCCCCGCCTGGGATCTCACAGATCAGGCCCCCACC
TCTGCCCCCACAGCCGCCCAGCCGCCTCCCGCAGAAGAAGCCTGCGCCGGGGGCTGACAAGTCCACCCCACTGACCAACAAAGGCCAACC
GAGAGGACCTGTGGATCTCTCTGCAACGGAAGCTCTGGGTCCTCTGTCCAATGCTATGGTCCTGCAGCCCCCTGCACCCATGCCTAGGAA
GTCGCAGGCAACCAAGTTGAAGCCTAAGCGGGTGAAAGCGCTCTATAACTGTGTGGCTGACAACCCCGATGAGCTCACCTTCTCCGAGGG
GGATGTGATCATCGTGGACGGGGAGGAGGACCAGGAGTGGTGGATTGGCCACATTGATGGAGATCCTGGTCGCAAAGGCGCATTCCCGGT
GTCATTTGTGCACTTTATCGCTGACTGAATTGCTACTGAACAAAAGCATTAACAGTTATGTTCCTGTTTCGTTATTGGTACCAAAACTCT
TGCCAGATAACCAGTTTCATGAACTGTTTGTATGGCAGCCCATGTTCTCTAATGCCACTGCTCTGTTTTAAAAACTCAGAGGCAATTTTT
ACATATCAGTAATTGTTTTTATAATTTGTGGTTTTCATGAAACATTGCTATGCATTTATTAGGAAAAACTGAATTTCCCAACAGGTGAAC
TGAAAAGTTATTTTAACTATTATACATAATCAAGATCCTGCCTCTACGGAATTAGCTAAACCTAAAAATGTTTGCATTAATGAATAAATT
CTTCCTGCATTCCTTGGCCCAGTTCTGGAGTTGGTGACCTTTATCACAATTATTATTTTAGGCGGCCAGTGAACTGCTGCTTCAGAAGTC
CATAGCCCAGCTCTGAACTTTCTCGATAAAATGCCATCAGTTCACCTTTAAAGACACACATTCCTTTGAAATCCACCCAGTGTTTAAAAA
GCAACTTGGAAATTTACACATTAGCATTGTACTTTCTAGCCCTAATTTGTGAGGTTGCAGCTATCATTATATTCTGCATGTATGTATAAC
CTGTTGTGAACAATCATACTTAACAAAACTACTGATGGTTTATGACAACGTAGGGTAACTACAGTTCATTCTGTTCCAGGTTATATAAAA
CTGCATTTCCTGAATTTGGTTAAAAACTAAGGATGATGGATTGCAAAACAGTTCTTTTAAATTAGTTTATATGCTTTAGGTGTTTTGGAA
TTTGCCTTCTTGAACTTCCTGAGTCACACAGAAAGCAACTGTACACAGTAGAATTCTGTGGCGCAGACCATGCTGTATTAACACATCACT
TGCTGTTTCCTACTGAGTGTACCACTGCCTTCCCTTCTAGCCCAGGAGAATGTTTACTCAGTTTAGTGTCTTGTATTTCTATAATACTCC
AACAGGAATGGTAGTCACACTGTCTTGAAATTGAATCTGTCCATCTGTTTATAATCAAGAACATATCAGAAATATATAGGTCCCAGGTAA
TACTCCCAAACATCCCACTTTTTACTGTTTCAGGCCATCATATCATTCTTAAGCTACTTGGGGTGGTAGTAGAGGATTAGGTTGTCTATT
ATAAAACCAAAACTCATTCGTTTAATGAACTTGACTGTCATACCTCTATTTAGTAATTGCGAGGGTAAGATTCATAGTAGGAATATTGGA
AATTTTGGCACTCTGAGAATAAATAGGCATATGATACCCACTTGGACTTTTAACAAAAGTAAAGGAATAAATTTGCATATAGGCTTGGAA
AGTGAGGCAGCAATGCTGTTAACTGCATTTGTTGTGATGGTGCATTTGATTGAAGCAGCTTGTCTTTATTATGCAAGACTGTGTAGAGTT
TTTTTTTTTTTTGGCATTGTACTTTTTGTTTTTGTTATAAAGGAAGACAGAACAAACTGGAATGTTTTATGATGTTGTATAGCAATCGCT
TTTTACCTTTCAAAGTTCCGGGTAAAAATGTGTTATATCTGTAGTTTTTTGTTTTTGTTTTTTTTTAAAGCACTACATCTGTTTTCACTA
ATTGTTAATTTCTGTTTGAACCCTTCATTTAATTTTCTCATAGATTTAAGTAAACAGATGTATTTTGCACAGTGCACTTATGTCTATTTT
AACAATCCTCCTGCATCTGTATTTTATAGTCAGCCTTTTGACCACCTGGTGCCAGCTATATAAGGAATAAAGTTGATTCATATCAACATT
AGAACTCCAGTCCCAAACTAATCTGTCAGGTTCACTGGTACATAAATACCTAGGAAATATTTTTCCAGTCTACAATTTGGTGCTATTGTG
CAGTAACTAATAGTACTCTTACCAGAGGAGAAATTATATTAACGACCCTGCTAATATCCTTTCTTAGTTATTTGCTCCTTGCAAATTAAA
AAAGCAACTAAGAGAAAGAAAAACATTGTAGATATCTATTTATATTTAAAGTTTATGTTTCATGAACTGCAGCTGCAGGATTCTGGCATT
TTGCATGCCATTCTCCATCAGATCTGGGATGATGGCTCAGAACATGTACACAGACTAAGAGTAACTGTGTGATCTGTTAAGGGGTGGATA
ACATAATATGCAGCTTAGGATGCTATTTTGAGATGTATGATATTCAGTTCATTCACCTGATTACTTTGGTTGCAGCACAACTGTATATAT
TGTATAACCGAAATTGATTATTTTCATTGTCCTTAATGCAGTGATTTATAATTAGAGCATGTTTAATAAGTTTACTCTTCTTGTTAACTA

>67000_67000_4_POLR2A-ASAP2_POLR2A_chr17_7388176_ENST00000572844_ASAP2_chr2_9419446_ENST00000315273_length(amino acids)=960AA_BP=36
MRLRSAPASAMHGGGPPSGDSACPLRTIKRVQFGVLSPDELALDVDRMVLYKMKKSVKAINSSGLAHVENEEQYTQALEKFGGNCVCRDD
PDLGSAFLKFSVFTKELTALFKNLIQNMNNIISFPLDSLLKGDLKGVKGDLKKPFDKAWKDYETKITKIEKEKKEHAKLHGMIRTEISGA
EIAEEMEKERRFFQLQMCEYLLKVNEIKIKKGVDLLQNLIKYFHAQCNFFQDGLKAVESLKPSIETLSTDLHTIKQAQDEERRQLIQLRD
ILKSALQVEQKEDSQIRQSTAYSLHQPQGNKEHGTERNGSLYKKSDGIRKVWQKRKCSVKNGFLTISHGTANRPPAKLNLLTCQVKTNPE
EKKCFDLISHDRTYHFQAEDEQECQIWMSVLQNSKEEALNNAFKGDDNTGENNIVQELTKEIISEVQRMTGNDVCCDCGAPDPTWLSTNL
GILTCIECSGIHRELGVHYSRMQSLTLDVLGTSELLLAKNIGNAGFNEIMECCLPAEDSVKPNPGSDMNARKDYITAKYIERRYARKKHA
DNAAKLHSLCEAVKTRDIFGLLQAYADGVDLTEKIPLANGHEPDETALHLAVRSVDRTSLHIVDFLVQNSGNLDKQTGKGSTALHYCCLT
DNAECLKLLLRGKASIEIANESGETPLDIAKRLKHEHCEELLTQALSGRFNSHVHVEYEWRLLHEDLDESDDDMDEKLQPSPNRREDRPI
SFYQLGSNQLQSNAVSLARDAANLAKEKQRAFMPSILQNETYGALLSGSPPPAQPAAPSTTSAPPLPPRNVGKDPLTPTPPPPVAKTPSV
MEALSQPSKPAPPGISQIRPPPLPPQPPSRLPQKKPAPGADKSTPLTNKGQPRGPVDLSATEALGPLSNAMVLQPPAPMPRKSQATKLKP

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Fusion Gene PPI Analysis for POLR2A-ASAP2


check button Go to ChiPPI (Chimeric Protein-Protein interactions) to see the chimeric PPI interaction in

ChiPPI page.


check button Protein-protein interactors with each fusion partner protein in wild-type (BIOGRID-3.4.160)
HgeneHgene's interactorsTgeneTgene's interactors


check button - Retained PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenStill interaction with


check button - Lost PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


check button - Retained PPIs, but lost function due to frame-shift fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


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Related Drugs for POLR2A-ASAP2


check button Drugs targeting genes involved in this fusion gene.
(DrugBank Version 5.1.8 2021-05-08)
PartnerGeneUniProtAccDrugBank IDDrug nameDrug activityDrug typeDrug status

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Related Diseases for POLR2A-ASAP2


check button Diseases associated with fusion partners.
(DisGeNet 4.0)
PartnerGeneDisease IDDisease name# pubmedsSource