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Center for Computational Systems Medicine
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Fusion Gene Summary

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Fusion Gene ORF analysis

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Fusion Genomic Features

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Fusion Protein Features

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Fusion Gene Sequence

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Fusion Gene PPI analysis

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Related Drugs

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Related Diseases

Fusion gene:POLR2A-SLC16A13 (FusionGDB2 ID:67008)

Fusion Gene Summary for POLR2A-SLC16A13

check button Fusion gene summary
Fusion gene informationFusion gene name: POLR2A-SLC16A13
Fusion gene ID: 67008
HgeneTgene
Gene symbol

POLR2A

SLC16A13

Gene ID

5430

201232

Gene nameRNA polymerase II subunit Asolute carrier family 16 member 13
SynonymsNEDHIB|POLR2|POLRA|RPB1|RPBh1|RPO2|RPOL2|RpIILS|hRPB220|hsRPB1MCT13
Cytomap

17p13.1

17p13.1

Type of geneprotein-codingprotein-coding
DescriptionDNA-directed RNA polymerase II subunit RPB1DNA-directed RNA polymerase II largest subunit, RNA polymerase II 220 kd subunitDNA-directed RNA polymerase II subunit ADNA-directed RNA polymerase III largest subunitRNA polymerase II subunit B1RNA-directedmonocarboxylate transporter 13MCT 13monocarboxylic acid transporter 13solute carrier family 16 (monocarboxylic acid transporters), member 13
Modification date2020032720200313
UniProtAcc..
Ensembl transtripts involved in fusion geneENST00000322644, ENST00000572844, 
ENST00000308027, 
Fusion gene scores* DoF score12 X 8 X 6=5763 X 5 X 2=30
# samples 134
** MAII scorelog2(13/576*10)=-2.14755718841386
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0		log2(4/30*10)=0.415037499278844
effective Gene in Pan-Cancer Fusion Genes (eGinPCFGs).
DoF>8 and MAII>0
Context

PubMed: POLR2A [Title/Abstract] AND SLC16A13 [Title/Abstract] AND fusion [Title/Abstract]

Most frequent breakpointPOLR2A(7399392)-SLC16A13(6941471), # samples:2
Anticipated loss of major functional domain due to fusion event.POLR2A-SLC16A13 seems lost the major protein functional domain in Hgene partner, which is a cell metabolism gene due to the frame-shifted ORF.
POLR2A-SLC16A13 seems lost the major protein functional domain in Tgene partner, which is a essential gene due to the frame-shifted ORF.
POLR2A-SLC16A13 seems lost the major protein functional domain in Tgene partner, which is a IUPHAR drug target due to the frame-shifted ORF.
* DoF score (Degree of Frequency) = # partners X # break points X # cancer types
** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10)

check button Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez
PartnerGeneGO IDGO termPubMed ID
HgenePOLR2A

GO:0006366

transcription by RNA polymerase II

9852112

HgenePOLR2A

GO:0033120

positive regulation of RNA splicing

21536736


check buttonFusion gene breakpoints across POLR2A (5'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.
all structure

check buttonFusion gene breakpoints across SLC16A13 (3'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.
all structure

check button Fusion gene information from two resources (ChiTars 5.0 and ChimerDB 4.0)
* All genome coordinats were lifted-over on hg19.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
SourceDiseaseSampleHgeneHchrHbpHstrandTgeneTchrTbpTstrand
ChimerDB4BRCATCGA-A8-A07O-01APOLR2Achr17

7399392

+SLC16A13chr17

6940046

+
ChimerDB4BRCATCGA-A8-A07O-01APOLR2Achr17

7399392

+SLC16A13chr17

6941471

+
ChimerDB4BRCATCGA-A8-A07OPOLR2Achr17

7399392

+SLC16A13chr17

6941470

+
ChimerDB4BRCATCGA-A8-A07OPOLR2Achr17

7399392

+SLC16A13chr17

6943081

+


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Fusion Gene ORF analysis for POLR2A-SLC16A13

check button Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
ORFHenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrand
Frame-shiftENST00000322644ENST00000308027POLR2Achr17

7399392

+SLC16A13chr17

6943081

+
Frame-shiftENST00000572844ENST00000308027POLR2Achr17

7399392

+SLC16A13chr17

6943081

+
In-frameENST00000322644ENST00000308027POLR2Achr17

7399392

+SLC16A13chr17

6940046

+
In-frameENST00000322644ENST00000308027POLR2Achr17

7399392

+SLC16A13chr17

6941471

+
In-frameENST00000322644ENST00000308027POLR2Achr17

7399392

+SLC16A13chr17

6941470

+
In-frameENST00000572844ENST00000308027POLR2Achr17

7399392

+SLC16A13chr17

6940046

+
In-frameENST00000572844ENST00000308027POLR2Achr17

7399392

+SLC16A13chr17

6941471

+
In-frameENST00000572844ENST00000308027POLR2Achr17

7399392

+SLC16A13chr17

6941470

+

check buttonORFfinder result based on the fusion transcript sequence of in-frame fusion genes.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandSeq length
(transcript)		BP loci
(transcript)		Predicted start
(transcript)		Predicted stop
(transcript)		Seq length
(amino acids)
ENST00000322644POLR2Achr177399392+ENST00000308027SLC16A13chr176941471+17226253691562397
ENST00000572844POLR2Achr177399392+ENST00000308027SLC16A13chr176941471+14683711151308397
ENST00000322644POLR2Achr177399392+ENST00000308027SLC16A13chr176941470+17226253691562397
ENST00000572844POLR2Achr177399392+ENST00000308027SLC16A13chr176941470+14683711151308397
ENST00000322644POLR2Achr177399392+ENST00000308027SLC16A13chr176940046+18666253691706445
ENST00000572844POLR2Achr177399392+ENST00000308027SLC16A13chr176940046+16123711151452445

check buttonDeepORF prediction of the coding potential based on the fusion transcript sequence of in-frame fusion genes. DeepORF is a coding potential classifier based on convolutional neural network by comparing the real Ribo-seq data. If the no-coding score < 0.5 and coding score > 0.5, then the in-frame fusion transcript is predicted as being likely translated.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandNo-coding scoreCoding score
ENST00000322644ENST00000308027POLR2Achr177399392+SLC16A13chr176941471+0.0898746850.9101253
ENST00000572844ENST00000308027POLR2Achr177399392+SLC16A13chr176941471+0.099552490.90044755
ENST00000322644ENST00000308027POLR2Achr177399392+SLC16A13chr176941470+0.0898746850.9101253
ENST00000572844ENST00000308027POLR2Achr177399392+SLC16A13chr176941470+0.099552490.90044755
ENST00000322644ENST00000308027POLR2Achr177399392+SLC16A13chr176940046+0.084888240.9151118
ENST00000572844ENST00000308027POLR2Achr177399392+SLC16A13chr176940046+0.0955598950.9044401

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Fusion Genomic Features for POLR2A-SLC16A13


check buttonFusionAI prediction of the potential fusion gene breakpoint based on the pre-mature RNA sequence context (+/- 5kb of individual partner genes, total 20kb length sequence). FusionAI is a fusion gene breakpoint classifier based on convolutional neural network by comparing the fusion positive and negative sequence context of ~ 20K fusion gene data. From here, we can have the relative potentency of the 20K genomic sequence how individual sequnce will be likely used as the gene fusion breakpoints.
HgeneHchrHbpHstrandTgeneTchrTbpTstrand1-pp (fusion gene breakpoint)
POLR2Achr177399392+SLC16A13chr176940045+0.9871880.012812045
POLR2Achr177399392+SLC16A13chr176941470+0.0004032690.9995968
POLR2Achr177399392+SLC16A13chr176941470+0.0004032690.9995968
POLR2Achr177399392+SLC16A13chr176943081+0.0001377810.9998622
POLR2Achr177399392+SLC16A13chr176940045+0.9871880.012812045
POLR2Achr177399392+SLC16A13chr176941470+0.0004032690.9995968
POLR2Achr177399392+SLC16A13chr176941470+0.0004032690.9995968
POLR2Achr177399392+SLC16A13chr176943081+0.0001377810.9998622

check buttonDistribution of 44 human genomic features loci across 20kb length fusion breakpoint regions. We integrated a total of 44 different types of human genomic feature loci information across five big categories including virus integration sites, repeats, structural variants, chromatin states, and gene expression regulation. More details are in help page.
genomic feature

check buttonDistribution of 44 human genomic features loci across 20kb length fusion breakpoint regions that are ovelapped with the top 1% feature importance score regions. More details are in help page.
genomic feature of top 1%

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Fusion Protein Features for POLR2A-SLC16A13


check button Four levels of functional features of fusion genes
Go to FGviewer search page for the most frequent breakpoint (https://ccsmweb.uth.edu/FGviewer/chr17:7399392/chr17:6941471)
- FGviewer provides the online visualization of the retention search of the protein functional features across DNA, RNA, protein, and pathological levels.
- How to search
1. Put your fusion gene symbol.
2. Press the tab key until there will be shown the breakpoint information filled.
4. Go down and press 'Search' tab twice.
4. Go down to have the hyperlink of the search result.
5. Click the hyperlink.
6. See the FGviewer result for your fusion gene.
FGviewer

check buttonMain function of each fusion partner protein. (from UniProt)
HgeneTgene
..
FUNCTION: Transcriptional activator which is required for calcium-dependent dendritic growth and branching in cortical neurons. Recruits CREB-binding protein (CREBBP) to nuclear bodies. Component of the CREST-BRG1 complex, a multiprotein complex that regulates promoter activation by orchestrating a calcium-dependent release of a repressor complex and a recruitment of an activator complex. In resting neurons, transcription of the c-FOS promoter is inhibited by BRG1-dependent recruitment of a phospho-RB1-HDAC1 repressor complex. Upon calcium influx, RB1 is dephosphorylated by calcineurin, which leads to release of the repressor complex. At the same time, there is increased recruitment of CREBBP to the promoter by a CREST-dependent mechanism, which leads to transcriptional activation. The CREST-BRG1 complex also binds to the NR2B promoter, and activity-dependent induction of NR2B expression involves a release of HDAC1 and recruitment of CREBBP (By similarity). {ECO:0000250}.FUNCTION: Transcriptional activator which is required for calcium-dependent dendritic growth and branching in cortical neurons. Recruits CREB-binding protein (CREBBP) to nuclear bodies. Component of the CREST-BRG1 complex, a multiprotein complex that regulates promoter activation by orchestrating a calcium-dependent release of a repressor complex and a recruitment of an activator complex. In resting neurons, transcription of the c-FOS promoter is inhibited by BRG1-dependent recruitment of a phospho-RB1-HDAC1 repressor complex. Upon calcium influx, RB1 is dephosphorylated by calcineurin, which leads to release of the repressor complex. At the same time, there is increased recruitment of CREBBP to the promoter by a CREST-dependent mechanism, which leads to transcriptional activation. The CREST-BRG1 complex also binds to the NR2B promoter, and activity-dependent induction of NR2B expression involves a release of HDAC1 and recruitment of CREBBP (By similarity). {ECO:0000250}.

check buttonRetention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at

download page


* Minus value of BPloci means that the break pointn is located before the CDS.
- In-frame and retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
TgeneSLC16A13chr17:7399392chr17:6940046ENST0000030802704395_42666427.0Topological domainCytoplasmic
TgeneSLC16A13chr17:7399392chr17:6941470ENST0000030802714395_426114427.0Topological domainCytoplasmic
TgeneSLC16A13chr17:7399392chr17:6941471ENST0000030802714395_426114427.0Topological domainCytoplasmic
TgeneSLC16A13chr17:7399392chr17:6940046ENST0000030802704106_12666427.0TransmembraneHelical
TgeneSLC16A13chr17:7399392chr17:6940046ENST0000030802704139_15966427.0TransmembraneHelical
TgeneSLC16A13chr17:7399392chr17:6940046ENST0000030802704169_18966427.0TransmembraneHelical
TgeneSLC16A13chr17:7399392chr17:6940046ENST0000030802704221_24166427.0TransmembraneHelical
TgeneSLC16A13chr17:7399392chr17:6940046ENST0000030802704252_27266427.0TransmembraneHelical
TgeneSLC16A13chr17:7399392chr17:6940046ENST0000030802704283_30366427.0TransmembraneHelical
TgeneSLC16A13chr17:7399392chr17:6940046ENST0000030802704306_32666427.0TransmembraneHelical
TgeneSLC16A13chr17:7399392chr17:6940046ENST0000030802704338_35866427.0TransmembraneHelical
TgeneSLC16A13chr17:7399392chr17:6940046ENST0000030802704374_39466427.0TransmembraneHelical
TgeneSLC16A13chr17:7399392chr17:6940046ENST000003080270481_10166427.0TransmembraneHelical
TgeneSLC16A13chr17:7399392chr17:6941470ENST0000030802714139_159114427.0TransmembraneHelical
TgeneSLC16A13chr17:7399392chr17:6941470ENST0000030802714169_189114427.0TransmembraneHelical
TgeneSLC16A13chr17:7399392chr17:6941470ENST0000030802714221_241114427.0TransmembraneHelical
TgeneSLC16A13chr17:7399392chr17:6941470ENST0000030802714252_272114427.0TransmembraneHelical
TgeneSLC16A13chr17:7399392chr17:6941470ENST0000030802714283_303114427.0TransmembraneHelical
TgeneSLC16A13chr17:7399392chr17:6941470ENST0000030802714306_326114427.0TransmembraneHelical
TgeneSLC16A13chr17:7399392chr17:6941470ENST0000030802714338_358114427.0TransmembraneHelical
TgeneSLC16A13chr17:7399392chr17:6941470ENST0000030802714374_394114427.0TransmembraneHelical
TgeneSLC16A13chr17:7399392chr17:6941471ENST0000030802714139_159114427.0TransmembraneHelical
TgeneSLC16A13chr17:7399392chr17:6941471ENST0000030802714169_189114427.0TransmembraneHelical
TgeneSLC16A13chr17:7399392chr17:6941471ENST0000030802714221_241114427.0TransmembraneHelical
TgeneSLC16A13chr17:7399392chr17:6941471ENST0000030802714252_272114427.0TransmembraneHelical
TgeneSLC16A13chr17:7399392chr17:6941471ENST0000030802714283_303114427.0TransmembraneHelical
TgeneSLC16A13chr17:7399392chr17:6941471ENST0000030802714306_326114427.0TransmembraneHelical
TgeneSLC16A13chr17:7399392chr17:6941471ENST0000030802714338_358114427.0TransmembraneHelical
TgeneSLC16A13chr17:7399392chr17:6941471ENST0000030802714374_394114427.0TransmembraneHelical

- In-frame and not-retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
HgenePOLR2Achr17:7399392chr17:6940046ENST00000322644+2291593_1960751971.0RegionNote=C-terminal domain (CTD)%3B 52 X 7 AA approximate tandem repeats of Y-[ST]-P-[STQ]-[ST]-P-[SRTEVKGN]
HgenePOLR2Achr17:7399392chr17:6940046ENST00000322644+229833_845751971.0RegionNote=Bridging helix
HgenePOLR2Achr17:7399392chr17:6941470ENST00000322644+2291593_1960751971.0RegionNote=C-terminal domain (CTD)%3B 52 X 7 AA approximate tandem repeats of Y-[ST]-P-[STQ]-[ST]-P-[SRTEVKGN]
HgenePOLR2Achr17:7399392chr17:6941470ENST00000322644+229833_845751971.0RegionNote=Bridging helix
HgenePOLR2Achr17:7399392chr17:6941471ENST00000322644+2291593_1960751971.0RegionNote=C-terminal domain (CTD)%3B 52 X 7 AA approximate tandem repeats of Y-[ST]-P-[STQ]-[ST]-P-[SRTEVKGN]
HgenePOLR2Achr17:7399392chr17:6941471ENST00000322644+229833_845751971.0RegionNote=Bridging helix
HgenePOLR2Achr17:7399392chr17:6940046ENST00000322644+2291593_1599751971.0RepeatNote=1
HgenePOLR2Achr17:7399392chr17:6940046ENST00000322644+2291600_1606751971.0RepeatNote=2%3B approximate
HgenePOLR2Achr17:7399392chr17:6940046ENST00000322644+2291608_1614751971.0RepeatNote=3
HgenePOLR2Achr17:7399392chr17:6940046ENST00000322644+2291615_1621751971.0RepeatNote=4
HgenePOLR2Achr17:7399392chr17:6940046ENST00000322644+2291622_1628751971.0RepeatNote=5
HgenePOLR2Achr17:7399392chr17:6940046ENST00000322644+2291629_1635751971.0RepeatNote=6
HgenePOLR2Achr17:7399392chr17:6940046ENST00000322644+2291636_1642751971.0RepeatNote=7
HgenePOLR2Achr17:7399392chr17:6940046ENST00000322644+2291643_1649751971.0RepeatNote=8
HgenePOLR2Achr17:7399392chr17:6940046ENST00000322644+2291650_1656751971.0RepeatNote=9
HgenePOLR2Achr17:7399392chr17:6940046ENST00000322644+2291657_1663751971.0RepeatNote=10
HgenePOLR2Achr17:7399392chr17:6940046ENST00000322644+2291664_1670751971.0RepeatNote=11
HgenePOLR2Achr17:7399392chr17:6940046ENST00000322644+2291671_1677751971.0RepeatNote=12
HgenePOLR2Achr17:7399392chr17:6940046ENST00000322644+2291678_1684751971.0RepeatNote=13
HgenePOLR2Achr17:7399392chr17:6940046ENST00000322644+2291685_1691751971.0RepeatNote=14
HgenePOLR2Achr17:7399392chr17:6940046ENST00000322644+2291692_1698751971.0RepeatNote=15
HgenePOLR2Achr17:7399392chr17:6940046ENST00000322644+2291699_1705751971.0RepeatNote=16
HgenePOLR2Achr17:7399392chr17:6940046ENST00000322644+2291706_1712751971.0RepeatNote=17
HgenePOLR2Achr17:7399392chr17:6940046ENST00000322644+2291713_1719751971.0RepeatNote=18
HgenePOLR2Achr17:7399392chr17:6940046ENST00000322644+2291720_1726751971.0RepeatNote=19
HgenePOLR2Achr17:7399392chr17:6940046ENST00000322644+2291727_1733751971.0RepeatNote=20
HgenePOLR2Achr17:7399392chr17:6940046ENST00000322644+2291734_1740751971.0RepeatNote=21
HgenePOLR2Achr17:7399392chr17:6940046ENST00000322644+2291741_1747751971.0RepeatNote=22
HgenePOLR2Achr17:7399392chr17:6940046ENST00000322644+2291748_1754751971.0RepeatNote=23
HgenePOLR2Achr17:7399392chr17:6940046ENST00000322644+2291755_1761751971.0RepeatNote=24
HgenePOLR2Achr17:7399392chr17:6940046ENST00000322644+2291762_1768751971.0RepeatNote=25
HgenePOLR2Achr17:7399392chr17:6940046ENST00000322644+2291769_1775751971.0RepeatNote=26
HgenePOLR2Achr17:7399392chr17:6940046ENST00000322644+2291776_1782751971.0RepeatNote=27
HgenePOLR2Achr17:7399392chr17:6940046ENST00000322644+2291783_1789751971.0RepeatNote=28
HgenePOLR2Achr17:7399392chr17:6940046ENST00000322644+2291790_1796751971.0RepeatNote=29
HgenePOLR2Achr17:7399392chr17:6940046ENST00000322644+2291797_1803751971.0RepeatNote=30
HgenePOLR2Achr17:7399392chr17:6940046ENST00000322644+2291804_1810751971.0RepeatNote=31
HgenePOLR2Achr17:7399392chr17:6940046ENST00000322644+2291811_1817751971.0RepeatNote=32
HgenePOLR2Achr17:7399392chr17:6940046ENST00000322644+2291818_1824751971.0RepeatNote=33
HgenePOLR2Achr17:7399392chr17:6940046ENST00000322644+2291825_1831751971.0RepeatNote=34
HgenePOLR2Achr17:7399392chr17:6940046ENST00000322644+2291832_1838751971.0RepeatNote=35
HgenePOLR2Achr17:7399392chr17:6940046ENST00000322644+2291839_1845751971.0RepeatNote=36
HgenePOLR2Achr17:7399392chr17:6940046ENST00000322644+2291846_1852751971.0RepeatNote=37
HgenePOLR2Achr17:7399392chr17:6940046ENST00000322644+2291853_1859751971.0RepeatNote=38
HgenePOLR2Achr17:7399392chr17:6940046ENST00000322644+2291860_1866751971.0RepeatNote=39
HgenePOLR2Achr17:7399392chr17:6940046ENST00000322644+2291867_1873751971.0RepeatNote=40
HgenePOLR2Achr17:7399392chr17:6940046ENST00000322644+2291874_1880751971.0RepeatNote=41
HgenePOLR2Achr17:7399392chr17:6940046ENST00000322644+2291881_1887751971.0RepeatNote=42
HgenePOLR2Achr17:7399392chr17:6940046ENST00000322644+2291888_1894751971.0RepeatNote=43
HgenePOLR2Achr17:7399392chr17:6940046ENST00000322644+2291895_1901751971.0RepeatNote=44
HgenePOLR2Achr17:7399392chr17:6940046ENST00000322644+2291902_1908751971.0RepeatNote=45
HgenePOLR2Achr17:7399392chr17:6940046ENST00000322644+2291909_1915751971.0RepeatNote=46
HgenePOLR2Achr17:7399392chr17:6940046ENST00000322644+2291916_1922751971.0RepeatNote=47
HgenePOLR2Achr17:7399392chr17:6940046ENST00000322644+2291923_1929751971.0RepeatNote=48
HgenePOLR2Achr17:7399392chr17:6940046ENST00000322644+2291930_1936751971.0RepeatNote=49
HgenePOLR2Achr17:7399392chr17:6940046ENST00000322644+2291940_1946751971.0RepeatNote=50
HgenePOLR2Achr17:7399392chr17:6940046ENST00000322644+2291947_1953751971.0RepeatNote=51%3B approximate
HgenePOLR2Achr17:7399392chr17:6940046ENST00000322644+2291954_1960751971.0RepeatNote=52%3B approximate
HgenePOLR2Achr17:7399392chr17:6941470ENST00000322644+2291593_1599751971.0RepeatNote=1
HgenePOLR2Achr17:7399392chr17:6941470ENST00000322644+2291600_1606751971.0RepeatNote=2%3B approximate
HgenePOLR2Achr17:7399392chr17:6941470ENST00000322644+2291608_1614751971.0RepeatNote=3
HgenePOLR2Achr17:7399392chr17:6941470ENST00000322644+2291615_1621751971.0RepeatNote=4
HgenePOLR2Achr17:7399392chr17:6941470ENST00000322644+2291622_1628751971.0RepeatNote=5
HgenePOLR2Achr17:7399392chr17:6941470ENST00000322644+2291629_1635751971.0RepeatNote=6
HgenePOLR2Achr17:7399392chr17:6941470ENST00000322644+2291636_1642751971.0RepeatNote=7
HgenePOLR2Achr17:7399392chr17:6941470ENST00000322644+2291643_1649751971.0RepeatNote=8
HgenePOLR2Achr17:7399392chr17:6941470ENST00000322644+2291650_1656751971.0RepeatNote=9
HgenePOLR2Achr17:7399392chr17:6941470ENST00000322644+2291657_1663751971.0RepeatNote=10
HgenePOLR2Achr17:7399392chr17:6941470ENST00000322644+2291664_1670751971.0RepeatNote=11
HgenePOLR2Achr17:7399392chr17:6941470ENST00000322644+2291671_1677751971.0RepeatNote=12
HgenePOLR2Achr17:7399392chr17:6941470ENST00000322644+2291678_1684751971.0RepeatNote=13
HgenePOLR2Achr17:7399392chr17:6941470ENST00000322644+2291685_1691751971.0RepeatNote=14
HgenePOLR2Achr17:7399392chr17:6941470ENST00000322644+2291692_1698751971.0RepeatNote=15
HgenePOLR2Achr17:7399392chr17:6941470ENST00000322644+2291699_1705751971.0RepeatNote=16
HgenePOLR2Achr17:7399392chr17:6941470ENST00000322644+2291706_1712751971.0RepeatNote=17
HgenePOLR2Achr17:7399392chr17:6941470ENST00000322644+2291713_1719751971.0RepeatNote=18
HgenePOLR2Achr17:7399392chr17:6941470ENST00000322644+2291720_1726751971.0RepeatNote=19
HgenePOLR2Achr17:7399392chr17:6941470ENST00000322644+2291727_1733751971.0RepeatNote=20
HgenePOLR2Achr17:7399392chr17:6941470ENST00000322644+2291734_1740751971.0RepeatNote=21
HgenePOLR2Achr17:7399392chr17:6941470ENST00000322644+2291741_1747751971.0RepeatNote=22
HgenePOLR2Achr17:7399392chr17:6941470ENST00000322644+2291748_1754751971.0RepeatNote=23
HgenePOLR2Achr17:7399392chr17:6941470ENST00000322644+2291755_1761751971.0RepeatNote=24
HgenePOLR2Achr17:7399392chr17:6941470ENST00000322644+2291762_1768751971.0RepeatNote=25
HgenePOLR2Achr17:7399392chr17:6941470ENST00000322644+2291769_1775751971.0RepeatNote=26
HgenePOLR2Achr17:7399392chr17:6941470ENST00000322644+2291776_1782751971.0RepeatNote=27
HgenePOLR2Achr17:7399392chr17:6941470ENST00000322644+2291783_1789751971.0RepeatNote=28
HgenePOLR2Achr17:7399392chr17:6941470ENST00000322644+2291790_1796751971.0RepeatNote=29
HgenePOLR2Achr17:7399392chr17:6941470ENST00000322644+2291797_1803751971.0RepeatNote=30
HgenePOLR2Achr17:7399392chr17:6941470ENST00000322644+2291804_1810751971.0RepeatNote=31
HgenePOLR2Achr17:7399392chr17:6941470ENST00000322644+2291811_1817751971.0RepeatNote=32
HgenePOLR2Achr17:7399392chr17:6941470ENST00000322644+2291818_1824751971.0RepeatNote=33
HgenePOLR2Achr17:7399392chr17:6941470ENST00000322644+2291825_1831751971.0RepeatNote=34
HgenePOLR2Achr17:7399392chr17:6941470ENST00000322644+2291832_1838751971.0RepeatNote=35
HgenePOLR2Achr17:7399392chr17:6941470ENST00000322644+2291839_1845751971.0RepeatNote=36
HgenePOLR2Achr17:7399392chr17:6941470ENST00000322644+2291846_1852751971.0RepeatNote=37
HgenePOLR2Achr17:7399392chr17:6941470ENST00000322644+2291853_1859751971.0RepeatNote=38
HgenePOLR2Achr17:7399392chr17:6941470ENST00000322644+2291860_1866751971.0RepeatNote=39
HgenePOLR2Achr17:7399392chr17:6941470ENST00000322644+2291867_1873751971.0RepeatNote=40
HgenePOLR2Achr17:7399392chr17:6941470ENST00000322644+2291874_1880751971.0RepeatNote=41
HgenePOLR2Achr17:7399392chr17:6941470ENST00000322644+2291881_1887751971.0RepeatNote=42
HgenePOLR2Achr17:7399392chr17:6941470ENST00000322644+2291888_1894751971.0RepeatNote=43
HgenePOLR2Achr17:7399392chr17:6941470ENST00000322644+2291895_1901751971.0RepeatNote=44
HgenePOLR2Achr17:7399392chr17:6941470ENST00000322644+2291902_1908751971.0RepeatNote=45
HgenePOLR2Achr17:7399392chr17:6941470ENST00000322644+2291909_1915751971.0RepeatNote=46
HgenePOLR2Achr17:7399392chr17:6941470ENST00000322644+2291916_1922751971.0RepeatNote=47
HgenePOLR2Achr17:7399392chr17:6941470ENST00000322644+2291923_1929751971.0RepeatNote=48
HgenePOLR2Achr17:7399392chr17:6941470ENST00000322644+2291930_1936751971.0RepeatNote=49
HgenePOLR2Achr17:7399392chr17:6941470ENST00000322644+2291940_1946751971.0RepeatNote=50
HgenePOLR2Achr17:7399392chr17:6941470ENST00000322644+2291947_1953751971.0RepeatNote=51%3B approximate
HgenePOLR2Achr17:7399392chr17:6941470ENST00000322644+2291954_1960751971.0RepeatNote=52%3B approximate
HgenePOLR2Achr17:7399392chr17:6941471ENST00000322644+2291593_1599751971.0RepeatNote=1
HgenePOLR2Achr17:7399392chr17:6941471ENST00000322644+2291600_1606751971.0RepeatNote=2%3B approximate
HgenePOLR2Achr17:7399392chr17:6941471ENST00000322644+2291608_1614751971.0RepeatNote=3
HgenePOLR2Achr17:7399392chr17:6941471ENST00000322644+2291615_1621751971.0RepeatNote=4
HgenePOLR2Achr17:7399392chr17:6941471ENST00000322644+2291622_1628751971.0RepeatNote=5
HgenePOLR2Achr17:7399392chr17:6941471ENST00000322644+2291629_1635751971.0RepeatNote=6
HgenePOLR2Achr17:7399392chr17:6941471ENST00000322644+2291636_1642751971.0RepeatNote=7
HgenePOLR2Achr17:7399392chr17:6941471ENST00000322644+2291643_1649751971.0RepeatNote=8
HgenePOLR2Achr17:7399392chr17:6941471ENST00000322644+2291650_1656751971.0RepeatNote=9
HgenePOLR2Achr17:7399392chr17:6941471ENST00000322644+2291657_1663751971.0RepeatNote=10
HgenePOLR2Achr17:7399392chr17:6941471ENST00000322644+2291664_1670751971.0RepeatNote=11
HgenePOLR2Achr17:7399392chr17:6941471ENST00000322644+2291671_1677751971.0RepeatNote=12
HgenePOLR2Achr17:7399392chr17:6941471ENST00000322644+2291678_1684751971.0RepeatNote=13
HgenePOLR2Achr17:7399392chr17:6941471ENST00000322644+2291685_1691751971.0RepeatNote=14
HgenePOLR2Achr17:7399392chr17:6941471ENST00000322644+2291692_1698751971.0RepeatNote=15
HgenePOLR2Achr17:7399392chr17:6941471ENST00000322644+2291699_1705751971.0RepeatNote=16
HgenePOLR2Achr17:7399392chr17:6941471ENST00000322644+2291706_1712751971.0RepeatNote=17
HgenePOLR2Achr17:7399392chr17:6941471ENST00000322644+2291713_1719751971.0RepeatNote=18
HgenePOLR2Achr17:7399392chr17:6941471ENST00000322644+2291720_1726751971.0RepeatNote=19
HgenePOLR2Achr17:7399392chr17:6941471ENST00000322644+2291727_1733751971.0RepeatNote=20
HgenePOLR2Achr17:7399392chr17:6941471ENST00000322644+2291734_1740751971.0RepeatNote=21
HgenePOLR2Achr17:7399392chr17:6941471ENST00000322644+2291741_1747751971.0RepeatNote=22
HgenePOLR2Achr17:7399392chr17:6941471ENST00000322644+2291748_1754751971.0RepeatNote=23
HgenePOLR2Achr17:7399392chr17:6941471ENST00000322644+2291755_1761751971.0RepeatNote=24
HgenePOLR2Achr17:7399392chr17:6941471ENST00000322644+2291762_1768751971.0RepeatNote=25
HgenePOLR2Achr17:7399392chr17:6941471ENST00000322644+2291769_1775751971.0RepeatNote=26
HgenePOLR2Achr17:7399392chr17:6941471ENST00000322644+2291776_1782751971.0RepeatNote=27
HgenePOLR2Achr17:7399392chr17:6941471ENST00000322644+2291783_1789751971.0RepeatNote=28
HgenePOLR2Achr17:7399392chr17:6941471ENST00000322644+2291790_1796751971.0RepeatNote=29
HgenePOLR2Achr17:7399392chr17:6941471ENST00000322644+2291797_1803751971.0RepeatNote=30
HgenePOLR2Achr17:7399392chr17:6941471ENST00000322644+2291804_1810751971.0RepeatNote=31
HgenePOLR2Achr17:7399392chr17:6941471ENST00000322644+2291811_1817751971.0RepeatNote=32
HgenePOLR2Achr17:7399392chr17:6941471ENST00000322644+2291818_1824751971.0RepeatNote=33
HgenePOLR2Achr17:7399392chr17:6941471ENST00000322644+2291825_1831751971.0RepeatNote=34
HgenePOLR2Achr17:7399392chr17:6941471ENST00000322644+2291832_1838751971.0RepeatNote=35
HgenePOLR2Achr17:7399392chr17:6941471ENST00000322644+2291839_1845751971.0RepeatNote=36
HgenePOLR2Achr17:7399392chr17:6941471ENST00000322644+2291846_1852751971.0RepeatNote=37
HgenePOLR2Achr17:7399392chr17:6941471ENST00000322644+2291853_1859751971.0RepeatNote=38
HgenePOLR2Achr17:7399392chr17:6941471ENST00000322644+2291860_1866751971.0RepeatNote=39
HgenePOLR2Achr17:7399392chr17:6941471ENST00000322644+2291867_1873751971.0RepeatNote=40
HgenePOLR2Achr17:7399392chr17:6941471ENST00000322644+2291874_1880751971.0RepeatNote=41
HgenePOLR2Achr17:7399392chr17:6941471ENST00000322644+2291881_1887751971.0RepeatNote=42
HgenePOLR2Achr17:7399392chr17:6941471ENST00000322644+2291888_1894751971.0RepeatNote=43
HgenePOLR2Achr17:7399392chr17:6941471ENST00000322644+2291895_1901751971.0RepeatNote=44
HgenePOLR2Achr17:7399392chr17:6941471ENST00000322644+2291902_1908751971.0RepeatNote=45
HgenePOLR2Achr17:7399392chr17:6941471ENST00000322644+2291909_1915751971.0RepeatNote=46
HgenePOLR2Achr17:7399392chr17:6941471ENST00000322644+2291916_1922751971.0RepeatNote=47
HgenePOLR2Achr17:7399392chr17:6941471ENST00000322644+2291923_1929751971.0RepeatNote=48
HgenePOLR2Achr17:7399392chr17:6941471ENST00000322644+2291930_1936751971.0RepeatNote=49
HgenePOLR2Achr17:7399392chr17:6941471ENST00000322644+2291940_1946751971.0RepeatNote=50
HgenePOLR2Achr17:7399392chr17:6941471ENST00000322644+2291947_1953751971.0RepeatNote=51%3B approximate
HgenePOLR2Achr17:7399392chr17:6941471ENST00000322644+2291954_1960751971.0RepeatNote=52%3B approximate
TgeneSLC16A13chr17:7399392chr17:6940046ENST00000308027041_1066427.0Topological domainCytoplasmic
TgeneSLC16A13chr17:7399392chr17:6941470ENST00000308027141_10114427.0Topological domainCytoplasmic
TgeneSLC16A13chr17:7399392chr17:6941471ENST00000308027141_10114427.0Topological domainCytoplasmic
TgeneSLC16A13chr17:7399392chr17:6940046ENST000003080270411_3166427.0TransmembraneHelical
TgeneSLC16A13chr17:7399392chr17:6940046ENST000003080270452_7266427.0TransmembraneHelical
TgeneSLC16A13chr17:7399392chr17:6941470ENST0000030802714106_126114427.0TransmembraneHelical
TgeneSLC16A13chr17:7399392chr17:6941470ENST000003080271411_31114427.0TransmembraneHelical
TgeneSLC16A13chr17:7399392chr17:6941470ENST000003080271452_72114427.0TransmembraneHelical
TgeneSLC16A13chr17:7399392chr17:6941470ENST000003080271481_101114427.0TransmembraneHelical
TgeneSLC16A13chr17:7399392chr17:6941471ENST0000030802714106_126114427.0TransmembraneHelical
TgeneSLC16A13chr17:7399392chr17:6941471ENST000003080271411_31114427.0TransmembraneHelical
TgeneSLC16A13chr17:7399392chr17:6941471ENST000003080271452_72114427.0TransmembraneHelical
TgeneSLC16A13chr17:7399392chr17:6941471ENST000003080271481_101114427.0TransmembraneHelical


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Fusion Gene Sequence for POLR2A-SLC16A13


check button For in-frame fusion transcripts, we provide the fusion transcript sequences and fusion amino acid sequences. To have fusion amino acid sequence, we ran ORFfinder and chose the longest ORF among the all predicted ones.
>67008_67008_1_POLR2A-SLC16A13_POLR2A_chr17_7399392_ENST00000322644_SLC16A13_chr17_6940046_ENST00000308027_length(transcript)=1866nt_BP=625nt
GCTCAGAAGCGCCGAGAGCGCGGCCGGGACGGTTGGAGAAGAAGGCGGCTCCCGGAAGGGGGAGAGACAAACTGCCGTAACCTCTGCCGT
TCAGGAACCCGGTTACTTATTTATTCGTTACCCTTTTTCTTCTTCCTCCCCCAAAAACCTTTTCCTTTTCCCTTCTTTTTTTTTCCTTTT
TGGGAGCTGAAAAATTTCCGGTAAGGGAAAGAAGGGCTCCTTTCGCTCCTTATTTCCCCGCCTCCTTCCCTCCCCCACCTTCCCCTCCTC
CGGCTTTTTCCTCCCAACTCGGGGAGGTCCTTCCCGGTGGCCGCCCTGACGAGGTCTGAGCACCTAGGCGGAGGCGGCGCAGGCTTTTTG
TAGTGAGGTTTGCGCCTGCGCAGCGCGCCTGCCTCCGCCATGCACGGGGGTGGCCCCCCCTCGGGGGACAGCGCATGCCCGCTGCGCACC
ATCAAGAGAGTCCAGTTCGGAGTCCTGAGTCCGGATGAACTGAAGCGAATGTCTGTGACGGAGGGTGGCATCAAATACCCAGAGACGACT
GAGGGAGGCCGCCCCAAGCTTGGGGGGCTGATGGACCCGAGGCAGGGGGTGATTGAGCGGACTGGCCGCTGCCAAACATGTGCAGGCCCG
GTAGGCAGTGCCCTGAGCACGAAGTTCGGGCCCAGGCCCGTGGTGATGACTGGAGGCATCTTGGCTGCGCTGGGGATGCTGCTCGCCTCT
TTTGCTACTTCCTTGACCCACCTATACCTGAGTATTGGGTTGCTGTCAGGCTCTGGCTGGGCTTTGACCTTCGCTCCGACCCTGGCCTGC
CTGTCCTGTTATTTCTCTCGCCGACGATCCCTGGCCACCGGGCTGGCACTGACAGGCGTGGGCCTCTCCTCCTTCACATTTGCCCCCTTT
TTCCAGTGGCTGCTCAGCCACTACGCCTGGAGGGGGTCCCTGCTGCTGGTGTCTGCCCTCTCCCTCCACCTAGTGGCCTGTGGTGCTCTC
CTCCGCCCACCCTCCCTGGCTGAGGACCCTGCTGTGGGTGGTCCCAGGGCCCAACTCACCTCTCTCCTCCATCATGGCCCCTTCCTCCGT
TACACTGTTGCCCTCACCCTGATCAACACTGGCTACTTCATTCCCTACCTCCACCTGGTGGCCCATCTCCAGGACCTGGATTGGGACCCA
CTACCTGCTGCCTTCCTACTCTCAGTTGTTGCTATTTCTGACCTCGTGGGGCGTGTGGTCTCCGGATGGCTGGGAGATGCAGTCCCAGGG
CCTGTGACACGACTCCTGATGCTCTGGACCACCTTGACTGGGGTGTCACTAGCCCTGTTCCCTGTAGCTCAGGCTCCCACAGCCCTGGTG
GCTCTGGCTGTGGCCTACGGCTTCACATCAGGGGCTCTGGCCCCACTGGCCTTCTCCGTGCTGCCTGAACTAATAGGGACTAGAAGGATT
TACTGTGGCCTGGGACTGTTGCAGATGATAGAGAGCATCGGGGGGCTGCTGGGGCCTCCTCTCTCAGGCTACCTCCGGGATGTGACAGGC
AACTACACGGCTTCTTTTGTGGTGGCTGGGGCCTTCCTTCTTTCAGGGAGTGGCATTCTCCTCACCCTGCCCCACTTCTTCTGCTTCTCA
ACTACTACCTCCGGGCCCCAGGACCTTGTAACAGAAGCACTAGATACTAAAGTTCCCCTACCCAAGGAGGGGCTGGAAGAGGACTGAACT
CCACAGAGTCAGGCCCAGAAAGCCAAAGCTTGACAGCTCCAGGTCTTCTCTTGCCACGTCTTGGTCTCCACAGAACCACAGTGCCTTAAG

>67008_67008_1_POLR2A-SLC16A13_POLR2A_chr17_7399392_ENST00000322644_SLC16A13_chr17_6940046_ENST00000308027_length(amino acids)=445AA_BP=85
MRLRSAPASAMHGGGPPSGDSACPLRTIKRVQFGVLSPDELKRMSVTEGGIKYPETTEGGRPKLGGLMDPRQGVIERTGRCQTCAGPVGS
ALSTKFGPRPVVMTGGILAALGMLLASFATSLTHLYLSIGLLSGSGWALTFAPTLACLSCYFSRRRSLATGLALTGVGLSSFTFAPFFQW
LLSHYAWRGSLLLVSALSLHLVACGALLRPPSLAEDPAVGGPRAQLTSLLHHGPFLRYTVALTLINTGYFIPYLHLVAHLQDLDWDPLPA
AFLLSVVAISDLVGRVVSGWLGDAVPGPVTRLLMLWTTLTGVSLALFPVAQAPTALVALAVAYGFTSGALAPLAFSVLPELIGTRRIYCG

--------------------------------------------------------------
>67008_67008_2_POLR2A-SLC16A13_POLR2A_chr17_7399392_ENST00000322644_SLC16A13_chr17_6941470_ENST00000308027_length(transcript)=1722nt_BP=625nt
GCTCAGAAGCGCCGAGAGCGCGGCCGGGACGGTTGGAGAAGAAGGCGGCTCCCGGAAGGGGGAGAGACAAACTGCCGTAACCTCTGCCGT
TCAGGAACCCGGTTACTTATTTATTCGTTACCCTTTTTCTTCTTCCTCCCCCAAAAACCTTTTCCTTTTCCCTTCTTTTTTTTTCCTTTT
TGGGAGCTGAAAAATTTCCGGTAAGGGAAAGAAGGGCTCCTTTCGCTCCTTATTTCCCCGCCTCCTTCCCTCCCCCACCTTCCCCTCCTC
CGGCTTTTTCCTCCCAACTCGGGGAGGTCCTTCCCGGTGGCCGCCCTGACGAGGTCTGAGCACCTAGGCGGAGGCGGCGCAGGCTTTTTG
TAGTGAGGTTTGCGCCTGCGCAGCGCGCCTGCCTCCGCCATGCACGGGGGTGGCCCCCCCTCGGGGGACAGCGCATGCCCGCTGCGCACC
ATCAAGAGAGTCCAGTTCGGAGTCCTGAGTCCGGATGAACTGAAGCGAATGTCTGTGACGGAGGGTGGCATCAAATACCCAGAGACGACT
GAGGGAGGCCGCCCCAAGCTTGGGGGGCTGATGGACCCGAGGCAGGGGGTGATTGAGCGGACTGGCCGCTGCCAAACATGTGCAGGCTCT
GGCTGGGCTTTGACCTTCGCTCCGACCCTGGCCTGCCTGTCCTGTTATTTCTCTCGCCGACGATCCCTGGCCACCGGGCTGGCACTGACA
GGCGTGGGCCTCTCCTCCTTCACATTTGCCCCCTTTTTCCAGTGGCTGCTCAGCCACTACGCCTGGAGGGGGTCCCTGCTGCTGGTGTCT
GCCCTCTCCCTCCACCTAGTGGCCTGTGGTGCTCTCCTCCGCCCACCCTCCCTGGCTGAGGACCCTGCTGTGGGTGGTCCCAGGGCCCAA
CTCACCTCTCTCCTCCATCATGGCCCCTTCCTCCGTTACACTGTTGCCCTCACCCTGATCAACACTGGCTACTTCATTCCCTACCTCCAC
CTGGTGGCCCATCTCCAGGACCTGGATTGGGACCCACTACCTGCTGCCTTCCTACTCTCAGTTGTTGCTATTTCTGACCTCGTGGGGCGT
GTGGTCTCCGGATGGCTGGGAGATGCAGTCCCAGGGCCTGTGACACGACTCCTGATGCTCTGGACCACCTTGACTGGGGTGTCACTAGCC
CTGTTCCCTGTAGCTCAGGCTCCCACAGCCCTGGTGGCTCTGGCTGTGGCCTACGGCTTCACATCAGGGGCTCTGGCCCCACTGGCCTTC
TCCGTGCTGCCTGAACTAATAGGGACTAGAAGGATTTACTGTGGCCTGGGACTGTTGCAGATGATAGAGAGCATCGGGGGGCTGCTGGGG
CCTCCTCTCTCAGGCTACCTCCGGGATGTGACAGGCAACTACACGGCTTCTTTTGTGGTGGCTGGGGCCTTCCTTCTTTCAGGGAGTGGC
ATTCTCCTCACCCTGCCCCACTTCTTCTGCTTCTCAACTACTACCTCCGGGCCCCAGGACCTTGTAACAGAAGCACTAGATACTAAAGTT
CCCCTACCCAAGGAGGGGCTGGAAGAGGACTGAACTCCACAGAGTCAGGCCCAGAAAGCCAAAGCTTGACAGCTCCAGGTCTTCTCTTGC
CACGTCTTGGTCTCCACAGAACCACAGTGCCTTAAGATTCTTGATCTGCCTCCCCCTAGAGCAGGCCTGGGGCTCCTGCAATGTGTGTGC

>67008_67008_2_POLR2A-SLC16A13_POLR2A_chr17_7399392_ENST00000322644_SLC16A13_chr17_6941470_ENST00000308027_length(amino acids)=397AA_BP=85
MRLRSAPASAMHGGGPPSGDSACPLRTIKRVQFGVLSPDELKRMSVTEGGIKYPETTEGGRPKLGGLMDPRQGVIERTGRCQTCAGSGWA
LTFAPTLACLSCYFSRRRSLATGLALTGVGLSSFTFAPFFQWLLSHYAWRGSLLLVSALSLHLVACGALLRPPSLAEDPAVGGPRAQLTS
LLHHGPFLRYTVALTLINTGYFIPYLHLVAHLQDLDWDPLPAAFLLSVVAISDLVGRVVSGWLGDAVPGPVTRLLMLWTTLTGVSLALFP
VAQAPTALVALAVAYGFTSGALAPLAFSVLPELIGTRRIYCGLGLLQMIESIGGLLGPPLSGYLRDVTGNYTASFVVAGAFLLSGSGILL

--------------------------------------------------------------
>67008_67008_3_POLR2A-SLC16A13_POLR2A_chr17_7399392_ENST00000322644_SLC16A13_chr17_6941471_ENST00000308027_length(transcript)=1722nt_BP=625nt
GCTCAGAAGCGCCGAGAGCGCGGCCGGGACGGTTGGAGAAGAAGGCGGCTCCCGGAAGGGGGAGAGACAAACTGCCGTAACCTCTGCCGT
TCAGGAACCCGGTTACTTATTTATTCGTTACCCTTTTTCTTCTTCCTCCCCCAAAAACCTTTTCCTTTTCCCTTCTTTTTTTTTCCTTTT
TGGGAGCTGAAAAATTTCCGGTAAGGGAAAGAAGGGCTCCTTTCGCTCCTTATTTCCCCGCCTCCTTCCCTCCCCCACCTTCCCCTCCTC
CGGCTTTTTCCTCCCAACTCGGGGAGGTCCTTCCCGGTGGCCGCCCTGACGAGGTCTGAGCACCTAGGCGGAGGCGGCGCAGGCTTTTTG
TAGTGAGGTTTGCGCCTGCGCAGCGCGCCTGCCTCCGCCATGCACGGGGGTGGCCCCCCCTCGGGGGACAGCGCATGCCCGCTGCGCACC
ATCAAGAGAGTCCAGTTCGGAGTCCTGAGTCCGGATGAACTGAAGCGAATGTCTGTGACGGAGGGTGGCATCAAATACCCAGAGACGACT
GAGGGAGGCCGCCCCAAGCTTGGGGGGCTGATGGACCCGAGGCAGGGGGTGATTGAGCGGACTGGCCGCTGCCAAACATGTGCAGGCTCT
GGCTGGGCTTTGACCTTCGCTCCGACCCTGGCCTGCCTGTCCTGTTATTTCTCTCGCCGACGATCCCTGGCCACCGGGCTGGCACTGACA
GGCGTGGGCCTCTCCTCCTTCACATTTGCCCCCTTTTTCCAGTGGCTGCTCAGCCACTACGCCTGGAGGGGGTCCCTGCTGCTGGTGTCT
GCCCTCTCCCTCCACCTAGTGGCCTGTGGTGCTCTCCTCCGCCCACCCTCCCTGGCTGAGGACCCTGCTGTGGGTGGTCCCAGGGCCCAA
CTCACCTCTCTCCTCCATCATGGCCCCTTCCTCCGTTACACTGTTGCCCTCACCCTGATCAACACTGGCTACTTCATTCCCTACCTCCAC
CTGGTGGCCCATCTCCAGGACCTGGATTGGGACCCACTACCTGCTGCCTTCCTACTCTCAGTTGTTGCTATTTCTGACCTCGTGGGGCGT
GTGGTCTCCGGATGGCTGGGAGATGCAGTCCCAGGGCCTGTGACACGACTCCTGATGCTCTGGACCACCTTGACTGGGGTGTCACTAGCC
CTGTTCCCTGTAGCTCAGGCTCCCACAGCCCTGGTGGCTCTGGCTGTGGCCTACGGCTTCACATCAGGGGCTCTGGCCCCACTGGCCTTC
TCCGTGCTGCCTGAACTAATAGGGACTAGAAGGATTTACTGTGGCCTGGGACTGTTGCAGATGATAGAGAGCATCGGGGGGCTGCTGGGG
CCTCCTCTCTCAGGCTACCTCCGGGATGTGACAGGCAACTACACGGCTTCTTTTGTGGTGGCTGGGGCCTTCCTTCTTTCAGGGAGTGGC
ATTCTCCTCACCCTGCCCCACTTCTTCTGCTTCTCAACTACTACCTCCGGGCCCCAGGACCTTGTAACAGAAGCACTAGATACTAAAGTT
CCCCTACCCAAGGAGGGGCTGGAAGAGGACTGAACTCCACAGAGTCAGGCCCAGAAAGCCAAAGCTTGACAGCTCCAGGTCTTCTCTTGC
CACGTCTTGGTCTCCACAGAACCACAGTGCCTTAAGATTCTTGATCTGCCTCCCCCTAGAGCAGGCCTGGGGCTCCTGCAATGTGTGTGC

>67008_67008_3_POLR2A-SLC16A13_POLR2A_chr17_7399392_ENST00000322644_SLC16A13_chr17_6941471_ENST00000308027_length(amino acids)=397AA_BP=85
MRLRSAPASAMHGGGPPSGDSACPLRTIKRVQFGVLSPDELKRMSVTEGGIKYPETTEGGRPKLGGLMDPRQGVIERTGRCQTCAGSGWA
LTFAPTLACLSCYFSRRRSLATGLALTGVGLSSFTFAPFFQWLLSHYAWRGSLLLVSALSLHLVACGALLRPPSLAEDPAVGGPRAQLTS
LLHHGPFLRYTVALTLINTGYFIPYLHLVAHLQDLDWDPLPAAFLLSVVAISDLVGRVVSGWLGDAVPGPVTRLLMLWTTLTGVSLALFP
VAQAPTALVALAVAYGFTSGALAPLAFSVLPELIGTRRIYCGLGLLQMIESIGGLLGPPLSGYLRDVTGNYTASFVVAGAFLLSGSGILL

--------------------------------------------------------------
>67008_67008_4_POLR2A-SLC16A13_POLR2A_chr17_7399392_ENST00000572844_SLC16A13_chr17_6940046_ENST00000308027_length(transcript)=1612nt_BP=371nt
CCACCTTCCCCTCCTCCGGCTTTTTCCTCCCAACTCGGGGAGGTCCTTCCCGGTGGCCGCCCTGACGAGGTCTGAGCACCTAGGCGGAGG
CGGCGCAGGCTTTTTGTAGTGAGGTTTGCGCCTGCGCAGCGCGCCTGCCTCCGCCATGCACGGGGGTGGCCCCCCCTCGGGGGACAGCGC
ATGCCCGCTGCGCACCATCAAGAGAGTCCAGTTCGGAGTCCTGAGTCCGGATGAACTGAAGCGAATGTCTGTGACGGAGGGTGGCATCAA
ATACCCAGAGACGACTGAGGGAGGCCGCCCCAAGCTTGGGGGGCTGATGGACCCGAGGCAGGGGGTGATTGAGCGGACTGGCCGCTGCCA
AACATGTGCAGGCCCGGTAGGCAGTGCCCTGAGCACGAAGTTCGGGCCCAGGCCCGTGGTGATGACTGGAGGCATCTTGGCTGCGCTGGG
GATGCTGCTCGCCTCTTTTGCTACTTCCTTGACCCACCTATACCTGAGTATTGGGTTGCTGTCAGGCTCTGGCTGGGCTTTGACCTTCGC
TCCGACCCTGGCCTGCCTGTCCTGTTATTTCTCTCGCCGACGATCCCTGGCCACCGGGCTGGCACTGACAGGCGTGGGCCTCTCCTCCTT
CACATTTGCCCCCTTTTTCCAGTGGCTGCTCAGCCACTACGCCTGGAGGGGGTCCCTGCTGCTGGTGTCTGCCCTCTCCCTCCACCTAGT
GGCCTGTGGTGCTCTCCTCCGCCCACCCTCCCTGGCTGAGGACCCTGCTGTGGGTGGTCCCAGGGCCCAACTCACCTCTCTCCTCCATCA
TGGCCCCTTCCTCCGTTACACTGTTGCCCTCACCCTGATCAACACTGGCTACTTCATTCCCTACCTCCACCTGGTGGCCCATCTCCAGGA
CCTGGATTGGGACCCACTACCTGCTGCCTTCCTACTCTCAGTTGTTGCTATTTCTGACCTCGTGGGGCGTGTGGTCTCCGGATGGCTGGG
AGATGCAGTCCCAGGGCCTGTGACACGACTCCTGATGCTCTGGACCACCTTGACTGGGGTGTCACTAGCCCTGTTCCCTGTAGCTCAGGC
TCCCACAGCCCTGGTGGCTCTGGCTGTGGCCTACGGCTTCACATCAGGGGCTCTGGCCCCACTGGCCTTCTCCGTGCTGCCTGAACTAAT
AGGGACTAGAAGGATTTACTGTGGCCTGGGACTGTTGCAGATGATAGAGAGCATCGGGGGGCTGCTGGGGCCTCCTCTCTCAGGCTACCT
CCGGGATGTGACAGGCAACTACACGGCTTCTTTTGTGGTGGCTGGGGCCTTCCTTCTTTCAGGGAGTGGCATTCTCCTCACCCTGCCCCA
CTTCTTCTGCTTCTCAACTACTACCTCCGGGCCCCAGGACCTTGTAACAGAAGCACTAGATACTAAAGTTCCCCTACCCAAGGAGGGGCT
GGAAGAGGACTGAACTCCACAGAGTCAGGCCCAGAAAGCCAAAGCTTGACAGCTCCAGGTCTTCTCTTGCCACGTCTTGGTCTCCACAGA

>67008_67008_4_POLR2A-SLC16A13_POLR2A_chr17_7399392_ENST00000572844_SLC16A13_chr17_6940046_ENST00000308027_length(amino acids)=445AA_BP=85
MRLRSAPASAMHGGGPPSGDSACPLRTIKRVQFGVLSPDELKRMSVTEGGIKYPETTEGGRPKLGGLMDPRQGVIERTGRCQTCAGPVGS
ALSTKFGPRPVVMTGGILAALGMLLASFATSLTHLYLSIGLLSGSGWALTFAPTLACLSCYFSRRRSLATGLALTGVGLSSFTFAPFFQW
LLSHYAWRGSLLLVSALSLHLVACGALLRPPSLAEDPAVGGPRAQLTSLLHHGPFLRYTVALTLINTGYFIPYLHLVAHLQDLDWDPLPA
AFLLSVVAISDLVGRVVSGWLGDAVPGPVTRLLMLWTTLTGVSLALFPVAQAPTALVALAVAYGFTSGALAPLAFSVLPELIGTRRIYCG

--------------------------------------------------------------
>67008_67008_5_POLR2A-SLC16A13_POLR2A_chr17_7399392_ENST00000572844_SLC16A13_chr17_6941470_ENST00000308027_length(transcript)=1468nt_BP=371nt
CCACCTTCCCCTCCTCCGGCTTTTTCCTCCCAACTCGGGGAGGTCCTTCCCGGTGGCCGCCCTGACGAGGTCTGAGCACCTAGGCGGAGG
CGGCGCAGGCTTTTTGTAGTGAGGTTTGCGCCTGCGCAGCGCGCCTGCCTCCGCCATGCACGGGGGTGGCCCCCCCTCGGGGGACAGCGC
ATGCCCGCTGCGCACCATCAAGAGAGTCCAGTTCGGAGTCCTGAGTCCGGATGAACTGAAGCGAATGTCTGTGACGGAGGGTGGCATCAA
ATACCCAGAGACGACTGAGGGAGGCCGCCCCAAGCTTGGGGGGCTGATGGACCCGAGGCAGGGGGTGATTGAGCGGACTGGCCGCTGCCA
AACATGTGCAGGCTCTGGCTGGGCTTTGACCTTCGCTCCGACCCTGGCCTGCCTGTCCTGTTATTTCTCTCGCCGACGATCCCTGGCCAC
CGGGCTGGCACTGACAGGCGTGGGCCTCTCCTCCTTCACATTTGCCCCCTTTTTCCAGTGGCTGCTCAGCCACTACGCCTGGAGGGGGTC
CCTGCTGCTGGTGTCTGCCCTCTCCCTCCACCTAGTGGCCTGTGGTGCTCTCCTCCGCCCACCCTCCCTGGCTGAGGACCCTGCTGTGGG
TGGTCCCAGGGCCCAACTCACCTCTCTCCTCCATCATGGCCCCTTCCTCCGTTACACTGTTGCCCTCACCCTGATCAACACTGGCTACTT
CATTCCCTACCTCCACCTGGTGGCCCATCTCCAGGACCTGGATTGGGACCCACTACCTGCTGCCTTCCTACTCTCAGTTGTTGCTATTTC
TGACCTCGTGGGGCGTGTGGTCTCCGGATGGCTGGGAGATGCAGTCCCAGGGCCTGTGACACGACTCCTGATGCTCTGGACCACCTTGAC
TGGGGTGTCACTAGCCCTGTTCCCTGTAGCTCAGGCTCCCACAGCCCTGGTGGCTCTGGCTGTGGCCTACGGCTTCACATCAGGGGCTCT
GGCCCCACTGGCCTTCTCCGTGCTGCCTGAACTAATAGGGACTAGAAGGATTTACTGTGGCCTGGGACTGTTGCAGATGATAGAGAGCAT
CGGGGGGCTGCTGGGGCCTCCTCTCTCAGGCTACCTCCGGGATGTGACAGGCAACTACACGGCTTCTTTTGTGGTGGCTGGGGCCTTCCT
TCTTTCAGGGAGTGGCATTCTCCTCACCCTGCCCCACTTCTTCTGCTTCTCAACTACTACCTCCGGGCCCCAGGACCTTGTAACAGAAGC
ACTAGATACTAAAGTTCCCCTACCCAAGGAGGGGCTGGAAGAGGACTGAACTCCACAGAGTCAGGCCCAGAAAGCCAAAGCTTGACAGCT
CCAGGTCTTCTCTTGCCACGTCTTGGTCTCCACAGAACCACAGTGCCTTAAGATTCTTGATCTGCCTCCCCCTAGAGCAGGCCTGGGGCT

>67008_67008_5_POLR2A-SLC16A13_POLR2A_chr17_7399392_ENST00000572844_SLC16A13_chr17_6941470_ENST00000308027_length(amino acids)=397AA_BP=85
MRLRSAPASAMHGGGPPSGDSACPLRTIKRVQFGVLSPDELKRMSVTEGGIKYPETTEGGRPKLGGLMDPRQGVIERTGRCQTCAGSGWA
LTFAPTLACLSCYFSRRRSLATGLALTGVGLSSFTFAPFFQWLLSHYAWRGSLLLVSALSLHLVACGALLRPPSLAEDPAVGGPRAQLTS
LLHHGPFLRYTVALTLINTGYFIPYLHLVAHLQDLDWDPLPAAFLLSVVAISDLVGRVVSGWLGDAVPGPVTRLLMLWTTLTGVSLALFP
VAQAPTALVALAVAYGFTSGALAPLAFSVLPELIGTRRIYCGLGLLQMIESIGGLLGPPLSGYLRDVTGNYTASFVVAGAFLLSGSGILL

--------------------------------------------------------------
>67008_67008_6_POLR2A-SLC16A13_POLR2A_chr17_7399392_ENST00000572844_SLC16A13_chr17_6941471_ENST00000308027_length(transcript)=1468nt_BP=371nt
CCACCTTCCCCTCCTCCGGCTTTTTCCTCCCAACTCGGGGAGGTCCTTCCCGGTGGCCGCCCTGACGAGGTCTGAGCACCTAGGCGGAGG
CGGCGCAGGCTTTTTGTAGTGAGGTTTGCGCCTGCGCAGCGCGCCTGCCTCCGCCATGCACGGGGGTGGCCCCCCCTCGGGGGACAGCGC
ATGCCCGCTGCGCACCATCAAGAGAGTCCAGTTCGGAGTCCTGAGTCCGGATGAACTGAAGCGAATGTCTGTGACGGAGGGTGGCATCAA
ATACCCAGAGACGACTGAGGGAGGCCGCCCCAAGCTTGGGGGGCTGATGGACCCGAGGCAGGGGGTGATTGAGCGGACTGGCCGCTGCCA
AACATGTGCAGGCTCTGGCTGGGCTTTGACCTTCGCTCCGACCCTGGCCTGCCTGTCCTGTTATTTCTCTCGCCGACGATCCCTGGCCAC
CGGGCTGGCACTGACAGGCGTGGGCCTCTCCTCCTTCACATTTGCCCCCTTTTTCCAGTGGCTGCTCAGCCACTACGCCTGGAGGGGGTC
CCTGCTGCTGGTGTCTGCCCTCTCCCTCCACCTAGTGGCCTGTGGTGCTCTCCTCCGCCCACCCTCCCTGGCTGAGGACCCTGCTGTGGG
TGGTCCCAGGGCCCAACTCACCTCTCTCCTCCATCATGGCCCCTTCCTCCGTTACACTGTTGCCCTCACCCTGATCAACACTGGCTACTT
CATTCCCTACCTCCACCTGGTGGCCCATCTCCAGGACCTGGATTGGGACCCACTACCTGCTGCCTTCCTACTCTCAGTTGTTGCTATTTC
TGACCTCGTGGGGCGTGTGGTCTCCGGATGGCTGGGAGATGCAGTCCCAGGGCCTGTGACACGACTCCTGATGCTCTGGACCACCTTGAC
TGGGGTGTCACTAGCCCTGTTCCCTGTAGCTCAGGCTCCCACAGCCCTGGTGGCTCTGGCTGTGGCCTACGGCTTCACATCAGGGGCTCT
GGCCCCACTGGCCTTCTCCGTGCTGCCTGAACTAATAGGGACTAGAAGGATTTACTGTGGCCTGGGACTGTTGCAGATGATAGAGAGCAT
CGGGGGGCTGCTGGGGCCTCCTCTCTCAGGCTACCTCCGGGATGTGACAGGCAACTACACGGCTTCTTTTGTGGTGGCTGGGGCCTTCCT
TCTTTCAGGGAGTGGCATTCTCCTCACCCTGCCCCACTTCTTCTGCTTCTCAACTACTACCTCCGGGCCCCAGGACCTTGTAACAGAAGC
ACTAGATACTAAAGTTCCCCTACCCAAGGAGGGGCTGGAAGAGGACTGAACTCCACAGAGTCAGGCCCAGAAAGCCAAAGCTTGACAGCT
CCAGGTCTTCTCTTGCCACGTCTTGGTCTCCACAGAACCACAGTGCCTTAAGATTCTTGATCTGCCTCCCCCTAGAGCAGGCCTGGGGCT

>67008_67008_6_POLR2A-SLC16A13_POLR2A_chr17_7399392_ENST00000572844_SLC16A13_chr17_6941471_ENST00000308027_length(amino acids)=397AA_BP=85
MRLRSAPASAMHGGGPPSGDSACPLRTIKRVQFGVLSPDELKRMSVTEGGIKYPETTEGGRPKLGGLMDPRQGVIERTGRCQTCAGSGWA
LTFAPTLACLSCYFSRRRSLATGLALTGVGLSSFTFAPFFQWLLSHYAWRGSLLLVSALSLHLVACGALLRPPSLAEDPAVGGPRAQLTS
LLHHGPFLRYTVALTLINTGYFIPYLHLVAHLQDLDWDPLPAAFLLSVVAISDLVGRVVSGWLGDAVPGPVTRLLMLWTTLTGVSLALFP
VAQAPTALVALAVAYGFTSGALAPLAFSVLPELIGTRRIYCGLGLLQMIESIGGLLGPPLSGYLRDVTGNYTASFVVAGAFLLSGSGILL

--------------------------------------------------------------

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Fusion Gene PPI Analysis for POLR2A-SLC16A13


check button Go to ChiPPI (Chimeric Protein-Protein interactions) to see the chimeric PPI interaction in

ChiPPI page.


check button Protein-protein interactors with each fusion partner protein in wild-type (BIOGRID-3.4.160)
HgeneHgene's interactorsTgeneTgene's interactors


check button - Retained PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenStill interaction with


check button - Lost PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


check button - Retained PPIs, but lost function due to frame-shift fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


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Related Drugs for POLR2A-SLC16A13


check button Drugs targeting genes involved in this fusion gene.
(DrugBank Version 5.1.8 2021-05-08)
PartnerGeneUniProtAccDrugBank IDDrug nameDrug activityDrug typeDrug status

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Related Diseases for POLR2A-SLC16A13


check button Diseases associated with fusion partners.
(DisGeNet 4.0)
PartnerGeneDisease IDDisease name# pubmedsSource