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Center for Computational Systems Medicine
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Fusion Gene Summary

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Fusion Gene ORF analysis

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Fusion Genomic Features

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Fusion Protein Features

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Fusion Gene Sequence

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Fusion Gene PPI analysis

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Related Drugs

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Related Diseases

Fusion gene:POLR2F-EIF3L (FusionGDB2 ID:67031)

Fusion Gene Summary for POLR2F-EIF3L

check button Fusion gene summary
Fusion gene informationFusion gene name: POLR2F-EIF3L
Fusion gene ID: 67031
HgeneTgene
Gene symbol

POLR2F

EIF3L

Gene ID

5435

51386

Gene nameRNA polymerase II subunit Feukaryotic translation initiation factor 3 subunit L
SynonymsHRBP14.4|POLRF|RPABC14.4|RPABC2|RPB14.4|RPB6|RPC15EIF3EIP|EIF3S11|EIF3S6IP|HSPC021|HSPC025|MSTP005
Cytomap

22q13.1

22q13.1

Type of geneprotein-codingprotein-coding
DescriptionDNA-directed RNA polymerases I, II, and III subunit RPABC2DNA-directed RNA polymerase II subunit FDNA-directed RNA polymerases I, II, and III 14.4 kDa polypeptideRNA Polymerase II subunit 14.4 kDRNA polymerases I, II, and III subunit ABC2polymerase (eukaryotic translation initiation factor 3 subunit LeIEF associated protein HSPC021eukaryotic translation initiation factor 3 subunit 6-interacting proteineukaryotic translation initiation factor 3 subunit E-interacting protein
Modification date2020031320200322
UniProtAcc.

Q9Y262

Ensembl transtripts involved in fusion geneENST00000488684, ENST00000405557, 
ENST00000407936, ENST00000442738, 
ENST00000460648, ENST00000470701, 
ENST00000606538, ENST00000608713, 
ENST00000381683, ENST00000412331, 
ENST00000406934, ENST00000476955, 
Fusion gene scores* DoF score13 X 12 X 6=93610 X 13 X 6=780
# samples 1413
** MAII scorelog2(14/936*10)=-2.74108170263844
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0		log2(13/780*10)=-2.58496250072116
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0
Context

PubMed: POLR2F [Title/Abstract] AND EIF3L [Title/Abstract] AND fusion [Title/Abstract]

Most frequent breakpointPOLR2F(38363177)-EIF3L(38251572), # samples:2
Anticipated loss of major functional domain due to fusion event.POLR2F-EIF3L seems lost the major protein functional domain in Hgene partner, which is a cell metabolism gene due to the frame-shifted ORF.
POLR2F-EIF3L seems lost the major protein functional domain in Hgene partner, which is a essential gene due to the frame-shifted ORF.
POLR2F-EIF3L seems lost the major protein functional domain in Tgene partner, which is a essential gene due to the frame-shifted ORF.
* DoF score (Degree of Frequency) = # partners X # break points X # cancer types
** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10)

check button Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez
PartnerGeneGO IDGO termPubMed ID
HgenePOLR2F

GO:0006366

transcription by RNA polymerase II

9852112

TgeneEIF3L

GO:0006413

translational initiation

17581632

TgeneEIF3L

GO:0075525

viral translational termination-reinitiation

21347434


check buttonFusion gene breakpoints across POLR2F (5'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.
all structure

check buttonFusion gene breakpoints across EIF3L (3'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.
all structure

check button Fusion gene information from two resources (ChiTars 5.0 and ChimerDB 4.0)
* All genome coordinats were lifted-over on hg19.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
SourceDiseaseSampleHgeneHchrHbpHstrandTgeneTchrTbpTstrand
ChimerDB4LIHCTCGA-ED-A82E-01APOLR2Fchr22

38363177

+EIF3Lchr22

38251572

+


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Fusion Gene ORF analysis for POLR2F-EIF3L

check button Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
ORFHenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrand
3UTR-3CDSENST00000488684ENST00000381683POLR2Fchr22

38363177

+EIF3Lchr22

38251572

+
3UTR-3CDSENST00000488684ENST00000412331POLR2Fchr22

38363177

+EIF3Lchr22

38251572

+
3UTR-intronENST00000488684ENST00000406934POLR2Fchr22

38363177

+EIF3Lchr22

38251572

+
3UTR-intronENST00000488684ENST00000476955POLR2Fchr22

38363177

+EIF3Lchr22

38251572

+
5CDS-intronENST00000405557ENST00000406934POLR2Fchr22

38363177

+EIF3Lchr22

38251572

+
5CDS-intronENST00000405557ENST00000476955POLR2Fchr22

38363177

+EIF3Lchr22

38251572

+
5CDS-intronENST00000407936ENST00000406934POLR2Fchr22

38363177

+EIF3Lchr22

38251572

+
5CDS-intronENST00000407936ENST00000476955POLR2Fchr22

38363177

+EIF3Lchr22

38251572

+
5CDS-intronENST00000442738ENST00000406934POLR2Fchr22

38363177

+EIF3Lchr22

38251572

+
5CDS-intronENST00000442738ENST00000476955POLR2Fchr22

38363177

+EIF3Lchr22

38251572

+
5CDS-intronENST00000460648ENST00000406934POLR2Fchr22

38363177

+EIF3Lchr22

38251572

+
5CDS-intronENST00000460648ENST00000476955POLR2Fchr22

38363177

+EIF3Lchr22

38251572

+
5CDS-intronENST00000470701ENST00000406934POLR2Fchr22

38363177

+EIF3Lchr22

38251572

+
5CDS-intronENST00000470701ENST00000476955POLR2Fchr22

38363177

+EIF3Lchr22

38251572

+
5CDS-intronENST00000606538ENST00000406934POLR2Fchr22

38363177

+EIF3Lchr22

38251572

+
5CDS-intronENST00000606538ENST00000476955POLR2Fchr22

38363177

+EIF3Lchr22

38251572

+
Frame-shiftENST00000460648ENST00000381683POLR2Fchr22

38363177

+EIF3Lchr22

38251572

+
Frame-shiftENST00000460648ENST00000412331POLR2Fchr22

38363177

+EIF3Lchr22

38251572

+
In-frameENST00000405557ENST00000381683POLR2Fchr22

38363177

+EIF3Lchr22

38251572

+
In-frameENST00000405557ENST00000412331POLR2Fchr22

38363177

+EIF3Lchr22

38251572

+
In-frameENST00000407936ENST00000381683POLR2Fchr22

38363177

+EIF3Lchr22

38251572

+
In-frameENST00000407936ENST00000412331POLR2Fchr22

38363177

+EIF3Lchr22

38251572

+
In-frameENST00000442738ENST00000381683POLR2Fchr22

38363177

+EIF3Lchr22

38251572

+
In-frameENST00000442738ENST00000412331POLR2Fchr22

38363177

+EIF3Lchr22

38251572

+
In-frameENST00000470701ENST00000381683POLR2Fchr22

38363177

+EIF3Lchr22

38251572

+
In-frameENST00000470701ENST00000412331POLR2Fchr22

38363177

+EIF3Lchr22

38251572

+
In-frameENST00000606538ENST00000381683POLR2Fchr22

38363177

+EIF3Lchr22

38251572

+
In-frameENST00000606538ENST00000412331POLR2Fchr22

38363177

+EIF3Lchr22

38251572

+
intron-3CDSENST00000608713ENST00000381683POLR2Fchr22

38363177

+EIF3Lchr22

38251572

+
intron-3CDSENST00000608713ENST00000412331POLR2Fchr22

38363177

+EIF3Lchr22

38251572

+
intron-intronENST00000608713ENST00000406934POLR2Fchr22

38363177

+EIF3Lchr22

38251572

+
intron-intronENST00000608713ENST00000476955POLR2Fchr22

38363177

+EIF3Lchr22

38251572

+

check buttonORFfinder result based on the fusion transcript sequence of in-frame fusion genes.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandSeq length
(transcript)		BP loci
(transcript)		Predicted start
(transcript)		Predicted stop
(transcript)		Seq length
(amino acids)
ENST00000407936POLR2Fchr2238363177+ENST00000412331EIF3Lchr2238251572+2729384911785564
ENST00000407936POLR2Fchr2238363177+ENST00000381683EIF3Lchr2238251572+1657384911641516
ENST00000405557POLR2Fchr2238363177+ENST00000412331EIF3Lchr2238251572+2715370771771564
ENST00000405557POLR2Fchr2238363177+ENST00000381683EIF3Lchr2238251572+1643370771627516
ENST00000442738POLR2Fchr2238363177+ENST00000412331EIF3Lchr2238251572+27634181251819564
ENST00000442738POLR2Fchr2238363177+ENST00000381683EIF3Lchr2238251572+16914181251675516
ENST00000606538POLR2Fchr2238363177+ENST00000412331EIF3Lchr2238251572+30336886442089481
ENST00000606538POLR2Fchr2238363177+ENST00000381683EIF3Lchr2238251572+19616886441945433
ENST00000470701POLR2Fchr2238363177+ENST00000412331EIF3Lchr2238251572+275240761808600
ENST00000470701POLR2Fchr2238363177+ENST00000381683EIF3Lchr2238251572+168040761664552

check buttonDeepORF prediction of the coding potential based on the fusion transcript sequence of in-frame fusion genes. DeepORF is a coding potential classifier based on convolutional neural network by comparing the real Ribo-seq data. If the no-coding score < 0.5 and coding score > 0.5, then the in-frame fusion transcript is predicted as being likely translated.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandNo-coding scoreCoding score
ENST00000407936ENST00000412331POLR2Fchr2238363177+EIF3Lchr2238251572+0.0013761120.99862385
ENST00000407936ENST00000381683POLR2Fchr2238363177+EIF3Lchr2238251572+0.0036037980.99639624
ENST00000405557ENST00000412331POLR2Fchr2238363177+EIF3Lchr2238251572+0.0013655460.9986344
ENST00000405557ENST00000381683POLR2Fchr2238363177+EIF3Lchr2238251572+0.00343820.9965618
ENST00000442738ENST00000412331POLR2Fchr2238363177+EIF3Lchr2238251572+0.0014352640.9985648
ENST00000442738ENST00000381683POLR2Fchr2238363177+EIF3Lchr2238251572+0.0038473730.9961526
ENST00000606538ENST00000412331POLR2Fchr2238363177+EIF3Lchr2238251572+0.0009652360.99903476
ENST00000606538ENST00000381683POLR2Fchr2238363177+EIF3Lchr2238251572+0.0011770850.99882287
ENST00000470701ENST00000412331POLR2Fchr2238363177+EIF3Lchr2238251572+0.0019145410.9980855
ENST00000470701ENST00000381683POLR2Fchr2238363177+EIF3Lchr2238251572+0.0031629830.996837

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Fusion Genomic Features for POLR2F-EIF3L


check buttonFusionAI prediction of the potential fusion gene breakpoint based on the pre-mature RNA sequence context (+/- 5kb of individual partner genes, total 20kb length sequence). FusionAI is a fusion gene breakpoint classifier based on convolutional neural network by comparing the fusion positive and negative sequence context of ~ 20K fusion gene data. From here, we can have the relative potentency of the 20K genomic sequence how individual sequnce will be likely used as the gene fusion breakpoints.
HgeneHchrHbpHstrandTgeneTchrTbpTstrand1-pp (fusion gene breakpoint)
POLR2Fchr2238363177+EIF3Lchr2238251571+4.92E-070.9999995
POLR2Fchr2238363177+EIF3Lchr2238251571+4.92E-070.9999995

check buttonDistribution of 44 human genomic features loci across 20kb length fusion breakpoint regions. We integrated a total of 44 different types of human genomic feature loci information across five big categories including virus integration sites, repeats, structural variants, chromatin states, and gene expression regulation. More details are in help page.
genomic feature

check buttonDistribution of 44 human genomic features loci across 20kb length fusion breakpoint regions that are ovelapped with the top 1% feature importance score regions. More details are in help page.
genomic feature of top 1%

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Fusion Protein Features for POLR2F-EIF3L


check button Four levels of functional features of fusion genes
Go to FGviewer search page for the most frequent breakpoint (https://ccsmweb.uth.edu/FGviewer/chr22:38363177/chr22:38251572)
- FGviewer provides the online visualization of the retention search of the protein functional features across DNA, RNA, protein, and pathological levels.
- How to search
1. Put your fusion gene symbol.
2. Press the tab key until there will be shown the breakpoint information filled.
4. Go down and press 'Search' tab twice.
4. Go down to have the hyperlink of the search result.
5. Click the hyperlink.
6. See the FGviewer result for your fusion gene.
FGviewer

check buttonMain function of each fusion partner protein. (from UniProt)
HgeneTgene
.EIF3L

Q9Y262

FUNCTION: Transcriptional activator which is required for calcium-dependent dendritic growth and branching in cortical neurons. Recruits CREB-binding protein (CREBBP) to nuclear bodies. Component of the CREST-BRG1 complex, a multiprotein complex that regulates promoter activation by orchestrating a calcium-dependent release of a repressor complex and a recruitment of an activator complex. In resting neurons, transcription of the c-FOS promoter is inhibited by BRG1-dependent recruitment of a phospho-RB1-HDAC1 repressor complex. Upon calcium influx, RB1 is dephosphorylated by calcineurin, which leads to release of the repressor complex. At the same time, there is increased recruitment of CREBBP to the promoter by a CREST-dependent mechanism, which leads to transcriptional activation. The CREST-BRG1 complex also binds to the NR2B promoter, and activity-dependent induction of NR2B expression involves a release of HDAC1 and recruitment of CREBBP (By similarity). {ECO:0000250}.FUNCTION: Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is required for several steps in the initiation of protein synthesis (PubMed:17581632, PubMed:25849773, PubMed:27462815). The eIF-3 complex associates with the 40S ribosome and facilitates the recruitment of eIF-1, eIF-1A, eIF-2:GTP:methionyl-tRNAi and eIF-5 to form the 43S pre-initiation complex (43S PIC). The eIF-3 complex stimulates mRNA recruitment to the 43S PIC and scanning of the mRNA for AUG recognition. The eIF-3 complex is also required for disassembly and recycling of post-termination ribosomal complexes and subsequently prevents premature joining of the 40S and 60S ribosomal subunits prior to initiation (PubMed:17581632). The eIF-3 complex specifically targets and initiates translation of a subset of mRNAs involved in cell proliferation, including cell cycling, differentiation and apoptosis, and uses different modes of RNA stem-loop binding to exert either translational activation or repression (PubMed:25849773). {ECO:0000255|HAMAP-Rule:MF_03011, ECO:0000269|PubMed:17581632, ECO:0000269|PubMed:25849773, ECO:0000269|PubMed:27462815}.; FUNCTION: (Microbial infection) In case of FCV infection, plays a role in the ribosomal termination-reinitiation event leading to the translation of VP2 (PubMed:18056426). {ECO:0000269|PubMed:18056426}.

check buttonRetention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at

download page


* Minus value of BPloci means that the break pointn is located before the CDS.
- In-frame and retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
TgeneEIF3Lchr22:38363177chr22:38251572ENST00000381683211331_53797517.0DomainPCI
TgeneEIF3Lchr22:38363177chr22:38251572ENST00000412331213331_53797565.0DomainPCI

- In-frame and not-retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note


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Fusion Gene Sequence for POLR2F-EIF3L


check button For in-frame fusion transcripts, we provide the fusion transcript sequences and fusion amino acid sequences. To have fusion amino acid sequence, we ran ORFfinder and chose the longest ORF among the all predicted ones.
>67031_67031_1_POLR2F-EIF3L_POLR2F_chr22_38363177_ENST00000405557_EIF3L_chr22_38251572_ENST00000381683_length(transcript)=1643nt_BP=370nt
GCGCGAGTCGTAGTGTCGCTGTTTGCGGGTCTCCGCGCGGGACCGGGGCGCAGCGGGGTCGCTGAGGCGAGGGTGTCATGTCAGACAACG
AGGACAATTTTGATGGCGACGACTTTGATGATGTGGAGGAGGATGAAGGGCTAGATGACTTGGAGAATGCCGAAGAGGAAGGCCAGGAGA
ATGTCGAGATCCTCCCCTCTGGGGAGCGACCGCAGGCCAACCAGAAGCGAATCACCACACCATACATGACCAAGTACGAGCGAGCCCGCG
TGCTGGGCACCCGAGCGCTCCAGATTGCGATGTGTGCCCCTGTGATGGTGGAGCTGGAGGGGGAGACAGATCCTCTGCTCATTGCCATGA
AGGAACTCAACTGGACCAAGCTGACTGAAAGATTCTTCAAGAATACACCTTGGCCCGAGGCTGAAGCCATTGCTCCACAGGTTGGCAATG
ATGCTGTCTTCCTGATTTTATACAAAGAATTATACTACAGGCACATATATGCCAAAGTCAGTTTTCAGTCATTCAGTCAGTACCGCTGTA
AGACTGCCAAGAAGTCAGAGGAGGAGATTGACTTTCTTCGTTCCAATCCCAAAATCTGGAATGTTCATAGTGTCCTCAATGTCCTTCATT
CCCTGGTAGACAAATCCAACATCAACCGACAGTTGGAGGTATACACAAGCGGAGGTGACCCTGAGAGTGTGGCTGGGGAGTATGGGCGGC
ACTCCCTCTACAAAATGCTTGGTTACTTCAGCCTGGTCGGGCTTCTCCGCCTGCACTCCCTGTTAGGAGATTACTACCAGGCCATCAAGG
TGCTGGAGAACATCGAACTGAACAAGAAGAGTATGTATTCCCGTGTGCCAGAGTGCCAGGTCACCACATACTATTATGTTGGGTTTGCAT
ATTTGATGATGCGTCGTTACCAGGATGCCATCCGGGTCTTCGCCAACATCCTCCTCTACATCCAGAGGACCAAGAGCATGTTCCAGAGGA
CCACGTACAAGTATGAGATGATTAACAAGCAGAATGAGCAGATGCATGCGCTGCTGGCCATTGCCCTCACGATGTACCCCATGCGTATTG
ATGAGAGCATTCACCTCCAGCTGCGGGAGAAATATGGGGACAAGATGTTGCGCATGCAGAAAGGTGACCCACAAGTCTATGAAGAACTTT
TCAGTTACTCCTGCCCCAAGTTCCTGTCGCCTGTAGTGCCCAACTATGATAATGTGCACCCCAACTACCACAAAGAGCCCTTCCTGCAGC
AGCTGAAGGTGTTTTCTGATGAAGTACAGCAGCAGGCCCAGCTTTCAACCATCCGCAGCTTCCTGAAGCTCTACACCACCATGCCTGTGG
CCAAGCTGGCTGGCTTCCTGGACCTCACAGAGCAGGAGTTCCGGATCCAGCTTCTTGTCTTCAAACACAAGATGAAGAACCTCGTGTGGA
CCAGCGGTATCTCAGCCCTGGATGGTGAATTTCAGTCAGCCTCAGAGGTTGACTTCTACATTGATAAGGACATGATCCACATCGCGGACA
CCAAGGTCGCCAGGCGTTATGGGGATTTCTTCATCCGTCAGATCCACAAATTTGAGGAGCTTAATCGAACCCTGAAGAAGATGGGACAGA

>67031_67031_1_POLR2F-EIF3L_POLR2F_chr22_38363177_ENST00000405557_EIF3L_chr22_38251572_ENST00000381683_length(amino acids)=516AA_BP=98
MSDNEDNFDGDDFDDVEEDEGLDDLENAEEEGQENVEILPSGERPQANQKRITTPYMTKYERARVLGTRALQIAMCAPVMVELEGETDPL
LIAMKELNWTKLTERFFKNTPWPEAEAIAPQVGNDAVFLILYKELYYRHIYAKVSFQSFSQYRCKTAKKSEEEIDFLRSNPKIWNVHSVL
NVLHSLVDKSNINRQLEVYTSGGDPESVAGEYGRHSLYKMLGYFSLVGLLRLHSLLGDYYQAIKVLENIELNKKSMYSRVPECQVTTYYY
VGFAYLMMRRYQDAIRVFANILLYIQRTKSMFQRTTYKYEMINKQNEQMHALLAIALTMYPMRIDESIHLQLREKYGDKMLRMQKGDPQV
YEELFSYSCPKFLSPVVPNYDNVHPNYHKEPFLQQLKVFSDEVQQQAQLSTIRSFLKLYTTMPVAKLAGFLDLTEQEFRIQLLVFKHKMK

--------------------------------------------------------------
>67031_67031_2_POLR2F-EIF3L_POLR2F_chr22_38363177_ENST00000405557_EIF3L_chr22_38251572_ENST00000412331_length(transcript)=2715nt_BP=370nt
GCGCGAGTCGTAGTGTCGCTGTTTGCGGGTCTCCGCGCGGGACCGGGGCGCAGCGGGGTCGCTGAGGCGAGGGTGTCATGTCAGACAACG
AGGACAATTTTGATGGCGACGACTTTGATGATGTGGAGGAGGATGAAGGGCTAGATGACTTGGAGAATGCCGAAGAGGAAGGCCAGGAGA
ATGTCGAGATCCTCCCCTCTGGGGAGCGACCGCAGGCCAACCAGAAGCGAATCACCACACCATACATGACCAAGTACGAGCGAGCCCGCG
TGCTGGGCACCCGAGCGCTCCAGATTGCGATGTGTGCCCCTGTGATGGTGGAGCTGGAGGGGGAGACAGATCCTCTGCTCATTGCCATGA
AGGAACTCAACTGGACCAAGCTGACTGAAAGATTCTTCAAGAATACACCTTGGCCCGAGGCTGAAGCCATTGCTCCACAGGTTGGCAATG
ATGCTGTCTTCCTGATTTTATACAAAGAATTATACTACAGGCACATATATGCCAAAGTCAGTGGGGGACCTTCCTTGGAGCAGAGGTTTG
AATCCTATTACAACTACTGCAATCTCTTCAACTACATTCTTAATGCCGATGGTCCTGCTCCCCTTGAACTACCCAACCAGTGGCTCTGGG
ATATTATCGATGAGTTCATCTACCAGTTTCAGTCATTCAGTCAGTACCGCTGTAAGACTGCCAAGAAGTCAGAGGAGGAGATTGACTTTC
TTCGTTCCAATCCCAAAATCTGGAATGTTCATAGTGTCCTCAATGTCCTTCATTCCCTGGTAGACAAATCCAACATCAACCGACAGTTGG
AGGTATACACAAGCGGAGGTGACCCTGAGAGTGTGGCTGGGGAGTATGGGCGGCACTCCCTCTACAAAATGCTTGGTTACTTCAGCCTGG
TCGGGCTTCTCCGCCTGCACTCCCTGTTAGGAGATTACTACCAGGCCATCAAGGTGCTGGAGAACATCGAACTGAACAAGAAGAGTATGT
ATTCCCGTGTGCCAGAGTGCCAGGTCACCACATACTATTATGTTGGGTTTGCATATTTGATGATGCGTCGTTACCAGGATGCCATCCGGG
TCTTCGCCAACATCCTCCTCTACATCCAGAGGACCAAGAGCATGTTCCAGAGGACCACGTACAAGTATGAGATGATTAACAAGCAGAATG
AGCAGATGCATGCGCTGCTGGCCATTGCCCTCACGATGTACCCCATGCGTATTGATGAGAGCATTCACCTCCAGCTGCGGGAGAAATATG
GGGACAAGATGTTGCGCATGCAGAAAGGTGACCCACAAGTCTATGAAGAACTTTTCAGTTACTCCTGCCCCAAGTTCCTGTCGCCTGTAG
TGCCCAACTATGATAATGTGCACCCCAACTACCACAAAGAGCCCTTCCTGCAGCAGCTGAAGGTGTTTTCTGATGAAGTACAGCAGCAGG
CCCAGCTTTCAACCATCCGCAGCTTCCTGAAGCTCTACACCACCATGCCTGTGGCCAAGCTGGCTGGCTTCCTGGACCTCACAGAGCAGG
AGTTCCGGATCCAGCTTCTTGTCTTCAAACACAAGATGAAGAACCTCGTGTGGACCAGCGGTATCTCAGCCCTGGATGGTGAATTTCAGT
CAGCCTCAGAGGTTGACTTCTACATTGATAAGGACATGATCCACATCGCGGACACCAAGGTCGCCAGGCGTTATGGGGATTTCTTCATCC
GTCAGATCCACAAATTTGAGGAGCTTAATCGAACCCTGAAGAAGATGGGACAGAGACCTTGATGATATTCACACACATTCAGGAACCTGT
TTTGATGTATTATAGGCAGGAAGTGTTTTTGCTACCGTGAAACCTTTACCTAGATCAGCCATCAGCCTGTCAACTCAGTTAACAAGTTAA
GGACCGAAGTGTTTCAAGTGGATCTCAGTAAAGGATCTTTGGAGCCAGATTTGTCGTCTCATTATTGTAGGAGAGAATTTGTGGGTTGTG
GCAGTAATACATTTCCCATGTGTCCTGATGCTTTCAGGATACATCAGTTGTTAGTGTTTAAATTGAGTTATTTTTATTTTGTGCTTTTGA
GATGGAGTCTCACTCTGTCTCCCAGGCTGGAGTGCAGTAGCGTGATCTCAGTTCGTTGCATCCTCCGCTGCCCAGGTTCAAGCAGTTCTG
CCTCAGCCTTCCAAGTAGCTGGGATTACAGGCGTGTGCCACCACACTCAGCTAATTTTTGTATTCTCAGTAGAGATGGGTTTTACCATGT
TGGCCAGGCTGGTCTCGAACTCCTGGCCTCAAGTGATTCGCCTGCCTTGGCCTCCCAAAATGTGCTAGGATTACAGGCATGAGCCACCAC
GCCCCGCCTAAATTCAAAATCTTTTTGTTTTTTTTTAGACGGAGTCTCACTCTGTCGCCCAGGTTGGAGTGTACTGGCGCGATCTCGGCT
CACTGCAAGCTCCACCTCCCAGGTTCCTGCCATTCTCCTGCCTCAGCCTCCCAAGTAGCTGGGACTACAGGCACCCGCCACCATGCCCGG
CCAATTTTTTGTATTTTTTAGTAGAGATGGGGTTTCACCGTGTTAGCCAGGATGGTCTCAGATTTCCTGACCTCGTGATCTGCCCATCTC
TGCCTCCTAAAGTACTGGGATTACAGGCGTGAGCCACCGTGCCCAGCCCTAAATTGAATTCTTAAATCCCTCTTGTTCATAAAGCAGTAT

>67031_67031_2_POLR2F-EIF3L_POLR2F_chr22_38363177_ENST00000405557_EIF3L_chr22_38251572_ENST00000412331_length(amino acids)=564AA_BP=98
MSDNEDNFDGDDFDDVEEDEGLDDLENAEEEGQENVEILPSGERPQANQKRITTPYMTKYERARVLGTRALQIAMCAPVMVELEGETDPL
LIAMKELNWTKLTERFFKNTPWPEAEAIAPQVGNDAVFLILYKELYYRHIYAKVSGGPSLEQRFESYYNYCNLFNYILNADGPAPLELPN
QWLWDIIDEFIYQFQSFSQYRCKTAKKSEEEIDFLRSNPKIWNVHSVLNVLHSLVDKSNINRQLEVYTSGGDPESVAGEYGRHSLYKMLG
YFSLVGLLRLHSLLGDYYQAIKVLENIELNKKSMYSRVPECQVTTYYYVGFAYLMMRRYQDAIRVFANILLYIQRTKSMFQRTTYKYEMI
NKQNEQMHALLAIALTMYPMRIDESIHLQLREKYGDKMLRMQKGDPQVYEELFSYSCPKFLSPVVPNYDNVHPNYHKEPFLQQLKVFSDE
VQQQAQLSTIRSFLKLYTTMPVAKLAGFLDLTEQEFRIQLLVFKHKMKNLVWTSGISALDGEFQSASEVDFYIDKDMIHIADTKVARRYG

--------------------------------------------------------------
>67031_67031_3_POLR2F-EIF3L_POLR2F_chr22_38363177_ENST00000407936_EIF3L_chr22_38251572_ENST00000381683_length(transcript)=1657nt_BP=384nt
ATAAGCTAGGAGCCGCGCGAGTCGTAGTGTCGCTGTTTGCGGGTCTCCGCGCGGGACCGGGGCGCAGCGGGGTCGCTGAGGCGAGGGTGT
CATGTCAGACAACGAGGACAATTTTGATGGCGACGACTTTGATGATGTGGAGGAGGATGAAGGGCTAGATGACTTGGAGAATGCCGAAGA
GGAAGGCCAGGAGAATGTCGAGATCCTCCCCTCTGGGGAGCGACCGCAGGCCAACCAGAAGCGAATCACCACACCATACATGACCAAGTA
CGAGCGAGCCCGCGTGCTGGGCACCCGAGCGCTCCAGATTGCGATGTGTGCCCCTGTGATGGTGGAGCTGGAGGGGGAGACAGATCCTCT
GCTCATTGCCATGAAGGAACTCAACTGGACCAAGCTGACTGAAAGATTCTTCAAGAATACACCTTGGCCCGAGGCTGAAGCCATTGCTCC
ACAGGTTGGCAATGATGCTGTCTTCCTGATTTTATACAAAGAATTATACTACAGGCACATATATGCCAAAGTCAGTTTTCAGTCATTCAG
TCAGTACCGCTGTAAGACTGCCAAGAAGTCAGAGGAGGAGATTGACTTTCTTCGTTCCAATCCCAAAATCTGGAATGTTCATAGTGTCCT
CAATGTCCTTCATTCCCTGGTAGACAAATCCAACATCAACCGACAGTTGGAGGTATACACAAGCGGAGGTGACCCTGAGAGTGTGGCTGG
GGAGTATGGGCGGCACTCCCTCTACAAAATGCTTGGTTACTTCAGCCTGGTCGGGCTTCTCCGCCTGCACTCCCTGTTAGGAGATTACTA
CCAGGCCATCAAGGTGCTGGAGAACATCGAACTGAACAAGAAGAGTATGTATTCCCGTGTGCCAGAGTGCCAGGTCACCACATACTATTA
TGTTGGGTTTGCATATTTGATGATGCGTCGTTACCAGGATGCCATCCGGGTCTTCGCCAACATCCTCCTCTACATCCAGAGGACCAAGAG
CATGTTCCAGAGGACCACGTACAAGTATGAGATGATTAACAAGCAGAATGAGCAGATGCATGCGCTGCTGGCCATTGCCCTCACGATGTA
CCCCATGCGTATTGATGAGAGCATTCACCTCCAGCTGCGGGAGAAATATGGGGACAAGATGTTGCGCATGCAGAAAGGTGACCCACAAGT
CTATGAAGAACTTTTCAGTTACTCCTGCCCCAAGTTCCTGTCGCCTGTAGTGCCCAACTATGATAATGTGCACCCCAACTACCACAAAGA
GCCCTTCCTGCAGCAGCTGAAGGTGTTTTCTGATGAAGTACAGCAGCAGGCCCAGCTTTCAACCATCCGCAGCTTCCTGAAGCTCTACAC
CACCATGCCTGTGGCCAAGCTGGCTGGCTTCCTGGACCTCACAGAGCAGGAGTTCCGGATCCAGCTTCTTGTCTTCAAACACAAGATGAA
GAACCTCGTGTGGACCAGCGGTATCTCAGCCCTGGATGGTGAATTTCAGTCAGCCTCAGAGGTTGACTTCTACATTGATAAGGACATGAT
CCACATCGCGGACACCAAGGTCGCCAGGCGTTATGGGGATTTCTTCATCCGTCAGATCCACAAATTTGAGGAGCTTAATCGAACCCTGAA

>67031_67031_3_POLR2F-EIF3L_POLR2F_chr22_38363177_ENST00000407936_EIF3L_chr22_38251572_ENST00000381683_length(amino acids)=516AA_BP=98
MSDNEDNFDGDDFDDVEEDEGLDDLENAEEEGQENVEILPSGERPQANQKRITTPYMTKYERARVLGTRALQIAMCAPVMVELEGETDPL
LIAMKELNWTKLTERFFKNTPWPEAEAIAPQVGNDAVFLILYKELYYRHIYAKVSFQSFSQYRCKTAKKSEEEIDFLRSNPKIWNVHSVL
NVLHSLVDKSNINRQLEVYTSGGDPESVAGEYGRHSLYKMLGYFSLVGLLRLHSLLGDYYQAIKVLENIELNKKSMYSRVPECQVTTYYY
VGFAYLMMRRYQDAIRVFANILLYIQRTKSMFQRTTYKYEMINKQNEQMHALLAIALTMYPMRIDESIHLQLREKYGDKMLRMQKGDPQV
YEELFSYSCPKFLSPVVPNYDNVHPNYHKEPFLQQLKVFSDEVQQQAQLSTIRSFLKLYTTMPVAKLAGFLDLTEQEFRIQLLVFKHKMK

--------------------------------------------------------------
>67031_67031_4_POLR2F-EIF3L_POLR2F_chr22_38363177_ENST00000407936_EIF3L_chr22_38251572_ENST00000412331_length(transcript)=2729nt_BP=384nt
ATAAGCTAGGAGCCGCGCGAGTCGTAGTGTCGCTGTTTGCGGGTCTCCGCGCGGGACCGGGGCGCAGCGGGGTCGCTGAGGCGAGGGTGT
CATGTCAGACAACGAGGACAATTTTGATGGCGACGACTTTGATGATGTGGAGGAGGATGAAGGGCTAGATGACTTGGAGAATGCCGAAGA
GGAAGGCCAGGAGAATGTCGAGATCCTCCCCTCTGGGGAGCGACCGCAGGCCAACCAGAAGCGAATCACCACACCATACATGACCAAGTA
CGAGCGAGCCCGCGTGCTGGGCACCCGAGCGCTCCAGATTGCGATGTGTGCCCCTGTGATGGTGGAGCTGGAGGGGGAGACAGATCCTCT
GCTCATTGCCATGAAGGAACTCAACTGGACCAAGCTGACTGAAAGATTCTTCAAGAATACACCTTGGCCCGAGGCTGAAGCCATTGCTCC
ACAGGTTGGCAATGATGCTGTCTTCCTGATTTTATACAAAGAATTATACTACAGGCACATATATGCCAAAGTCAGTGGGGGACCTTCCTT
GGAGCAGAGGTTTGAATCCTATTACAACTACTGCAATCTCTTCAACTACATTCTTAATGCCGATGGTCCTGCTCCCCTTGAACTACCCAA
CCAGTGGCTCTGGGATATTATCGATGAGTTCATCTACCAGTTTCAGTCATTCAGTCAGTACCGCTGTAAGACTGCCAAGAAGTCAGAGGA
GGAGATTGACTTTCTTCGTTCCAATCCCAAAATCTGGAATGTTCATAGTGTCCTCAATGTCCTTCATTCCCTGGTAGACAAATCCAACAT
CAACCGACAGTTGGAGGTATACACAAGCGGAGGTGACCCTGAGAGTGTGGCTGGGGAGTATGGGCGGCACTCCCTCTACAAAATGCTTGG
TTACTTCAGCCTGGTCGGGCTTCTCCGCCTGCACTCCCTGTTAGGAGATTACTACCAGGCCATCAAGGTGCTGGAGAACATCGAACTGAA
CAAGAAGAGTATGTATTCCCGTGTGCCAGAGTGCCAGGTCACCACATACTATTATGTTGGGTTTGCATATTTGATGATGCGTCGTTACCA
GGATGCCATCCGGGTCTTCGCCAACATCCTCCTCTACATCCAGAGGACCAAGAGCATGTTCCAGAGGACCACGTACAAGTATGAGATGAT
TAACAAGCAGAATGAGCAGATGCATGCGCTGCTGGCCATTGCCCTCACGATGTACCCCATGCGTATTGATGAGAGCATTCACCTCCAGCT
GCGGGAGAAATATGGGGACAAGATGTTGCGCATGCAGAAAGGTGACCCACAAGTCTATGAAGAACTTTTCAGTTACTCCTGCCCCAAGTT
CCTGTCGCCTGTAGTGCCCAACTATGATAATGTGCACCCCAACTACCACAAAGAGCCCTTCCTGCAGCAGCTGAAGGTGTTTTCTGATGA
AGTACAGCAGCAGGCCCAGCTTTCAACCATCCGCAGCTTCCTGAAGCTCTACACCACCATGCCTGTGGCCAAGCTGGCTGGCTTCCTGGA
CCTCACAGAGCAGGAGTTCCGGATCCAGCTTCTTGTCTTCAAACACAAGATGAAGAACCTCGTGTGGACCAGCGGTATCTCAGCCCTGGA
TGGTGAATTTCAGTCAGCCTCAGAGGTTGACTTCTACATTGATAAGGACATGATCCACATCGCGGACACCAAGGTCGCCAGGCGTTATGG
GGATTTCTTCATCCGTCAGATCCACAAATTTGAGGAGCTTAATCGAACCCTGAAGAAGATGGGACAGAGACCTTGATGATATTCACACAC
ATTCAGGAACCTGTTTTGATGTATTATAGGCAGGAAGTGTTTTTGCTACCGTGAAACCTTTACCTAGATCAGCCATCAGCCTGTCAACTC
AGTTAACAAGTTAAGGACCGAAGTGTTTCAAGTGGATCTCAGTAAAGGATCTTTGGAGCCAGATTTGTCGTCTCATTATTGTAGGAGAGA
ATTTGTGGGTTGTGGCAGTAATACATTTCCCATGTGTCCTGATGCTTTCAGGATACATCAGTTGTTAGTGTTTAAATTGAGTTATTTTTA
TTTTGTGCTTTTGAGATGGAGTCTCACTCTGTCTCCCAGGCTGGAGTGCAGTAGCGTGATCTCAGTTCGTTGCATCCTCCGCTGCCCAGG
TTCAAGCAGTTCTGCCTCAGCCTTCCAAGTAGCTGGGATTACAGGCGTGTGCCACCACACTCAGCTAATTTTTGTATTCTCAGTAGAGAT
GGGTTTTACCATGTTGGCCAGGCTGGTCTCGAACTCCTGGCCTCAAGTGATTCGCCTGCCTTGGCCTCCCAAAATGTGCTAGGATTACAG
GCATGAGCCACCACGCCCCGCCTAAATTCAAAATCTTTTTGTTTTTTTTTAGACGGAGTCTCACTCTGTCGCCCAGGTTGGAGTGTACTG
GCGCGATCTCGGCTCACTGCAAGCTCCACCTCCCAGGTTCCTGCCATTCTCCTGCCTCAGCCTCCCAAGTAGCTGGGACTACAGGCACCC
GCCACCATGCCCGGCCAATTTTTTGTATTTTTTAGTAGAGATGGGGTTTCACCGTGTTAGCCAGGATGGTCTCAGATTTCCTGACCTCGT
GATCTGCCCATCTCTGCCTCCTAAAGTACTGGGATTACAGGCGTGAGCCACCGTGCCCAGCCCTAAATTGAATTCTTAAATCCCTCTTGT

>67031_67031_4_POLR2F-EIF3L_POLR2F_chr22_38363177_ENST00000407936_EIF3L_chr22_38251572_ENST00000412331_length(amino acids)=564AA_BP=98
MSDNEDNFDGDDFDDVEEDEGLDDLENAEEEGQENVEILPSGERPQANQKRITTPYMTKYERARVLGTRALQIAMCAPVMVELEGETDPL
LIAMKELNWTKLTERFFKNTPWPEAEAIAPQVGNDAVFLILYKELYYRHIYAKVSGGPSLEQRFESYYNYCNLFNYILNADGPAPLELPN
QWLWDIIDEFIYQFQSFSQYRCKTAKKSEEEIDFLRSNPKIWNVHSVLNVLHSLVDKSNINRQLEVYTSGGDPESVAGEYGRHSLYKMLG
YFSLVGLLRLHSLLGDYYQAIKVLENIELNKKSMYSRVPECQVTTYYYVGFAYLMMRRYQDAIRVFANILLYIQRTKSMFQRTTYKYEMI
NKQNEQMHALLAIALTMYPMRIDESIHLQLREKYGDKMLRMQKGDPQVYEELFSYSCPKFLSPVVPNYDNVHPNYHKEPFLQQLKVFSDE
VQQQAQLSTIRSFLKLYTTMPVAKLAGFLDLTEQEFRIQLLVFKHKMKNLVWTSGISALDGEFQSASEVDFYIDKDMIHIADTKVARRYG

--------------------------------------------------------------
>67031_67031_5_POLR2F-EIF3L_POLR2F_chr22_38363177_ENST00000442738_EIF3L_chr22_38251572_ENST00000381683_length(transcript)=1691nt_BP=418nt
AGTGATTTCCTCTGGGTTACGGCGCAGGCGCAAGATAAGCTAGGAGCCGCGCGAGTCGTAGTGTCGCTGTTTGCGGGTCTCCGCGCGGGA
CCGGGGCGCAGCGGGGTCGCTGAGGCGAGGGTGTCATGTCAGACAACGAGGACAATTTTGATGGCGACGACTTTGATGATGTGGAGGAGG
ATGAAGGGCTAGATGACTTGGAGAATGCCGAAGAGGAAGGCCAGGAGAATGTCGAGATCCTCCCCTCTGGGGAGCGACCGCAGGCCAACC
AGAAGCGAATCACCACACCATACATGACCAAGTACGAGCGAGCCCGCGTGCTGGGCACCCGAGCGCTCCAGATTGCGATGTGTGCCCCTG
TGATGGTGGAGCTGGAGGGGGAGACAGATCCTCTGCTCATTGCCATGAAGGAACTCAACTGGACCAAGCTGACTGAAAGATTCTTCAAGA
ATACACCTTGGCCCGAGGCTGAAGCCATTGCTCCACAGGTTGGCAATGATGCTGTCTTCCTGATTTTATACAAAGAATTATACTACAGGC
ACATATATGCCAAAGTCAGTTTTCAGTCATTCAGTCAGTACCGCTGTAAGACTGCCAAGAAGTCAGAGGAGGAGATTGACTTTCTTCGTT
CCAATCCCAAAATCTGGAATGTTCATAGTGTCCTCAATGTCCTTCATTCCCTGGTAGACAAATCCAACATCAACCGACAGTTGGAGGTAT
ACACAAGCGGAGGTGACCCTGAGAGTGTGGCTGGGGAGTATGGGCGGCACTCCCTCTACAAAATGCTTGGTTACTTCAGCCTGGTCGGGC
TTCTCCGCCTGCACTCCCTGTTAGGAGATTACTACCAGGCCATCAAGGTGCTGGAGAACATCGAACTGAACAAGAAGAGTATGTATTCCC
GTGTGCCAGAGTGCCAGGTCACCACATACTATTATGTTGGGTTTGCATATTTGATGATGCGTCGTTACCAGGATGCCATCCGGGTCTTCG
CCAACATCCTCCTCTACATCCAGAGGACCAAGAGCATGTTCCAGAGGACCACGTACAAGTATGAGATGATTAACAAGCAGAATGAGCAGA
TGCATGCGCTGCTGGCCATTGCCCTCACGATGTACCCCATGCGTATTGATGAGAGCATTCACCTCCAGCTGCGGGAGAAATATGGGGACA
AGATGTTGCGCATGCAGAAAGGTGACCCACAAGTCTATGAAGAACTTTTCAGTTACTCCTGCCCCAAGTTCCTGTCGCCTGTAGTGCCCA
ACTATGATAATGTGCACCCCAACTACCACAAAGAGCCCTTCCTGCAGCAGCTGAAGGTGTTTTCTGATGAAGTACAGCAGCAGGCCCAGC
TTTCAACCATCCGCAGCTTCCTGAAGCTCTACACCACCATGCCTGTGGCCAAGCTGGCTGGCTTCCTGGACCTCACAGAGCAGGAGTTCC
GGATCCAGCTTCTTGTCTTCAAACACAAGATGAAGAACCTCGTGTGGACCAGCGGTATCTCAGCCCTGGATGGTGAATTTCAGTCAGCCT
CAGAGGTTGACTTCTACATTGATAAGGACATGATCCACATCGCGGACACCAAGGTCGCCAGGCGTTATGGGGATTTCTTCATCCGTCAGA

>67031_67031_5_POLR2F-EIF3L_POLR2F_chr22_38363177_ENST00000442738_EIF3L_chr22_38251572_ENST00000381683_length(amino acids)=516AA_BP=98
MSDNEDNFDGDDFDDVEEDEGLDDLENAEEEGQENVEILPSGERPQANQKRITTPYMTKYERARVLGTRALQIAMCAPVMVELEGETDPL
LIAMKELNWTKLTERFFKNTPWPEAEAIAPQVGNDAVFLILYKELYYRHIYAKVSFQSFSQYRCKTAKKSEEEIDFLRSNPKIWNVHSVL
NVLHSLVDKSNINRQLEVYTSGGDPESVAGEYGRHSLYKMLGYFSLVGLLRLHSLLGDYYQAIKVLENIELNKKSMYSRVPECQVTTYYY
VGFAYLMMRRYQDAIRVFANILLYIQRTKSMFQRTTYKYEMINKQNEQMHALLAIALTMYPMRIDESIHLQLREKYGDKMLRMQKGDPQV
YEELFSYSCPKFLSPVVPNYDNVHPNYHKEPFLQQLKVFSDEVQQQAQLSTIRSFLKLYTTMPVAKLAGFLDLTEQEFRIQLLVFKHKMK

--------------------------------------------------------------
>67031_67031_6_POLR2F-EIF3L_POLR2F_chr22_38363177_ENST00000442738_EIF3L_chr22_38251572_ENST00000412331_length(transcript)=2763nt_BP=418nt
AGTGATTTCCTCTGGGTTACGGCGCAGGCGCAAGATAAGCTAGGAGCCGCGCGAGTCGTAGTGTCGCTGTTTGCGGGTCTCCGCGCGGGA
CCGGGGCGCAGCGGGGTCGCTGAGGCGAGGGTGTCATGTCAGACAACGAGGACAATTTTGATGGCGACGACTTTGATGATGTGGAGGAGG
ATGAAGGGCTAGATGACTTGGAGAATGCCGAAGAGGAAGGCCAGGAGAATGTCGAGATCCTCCCCTCTGGGGAGCGACCGCAGGCCAACC
AGAAGCGAATCACCACACCATACATGACCAAGTACGAGCGAGCCCGCGTGCTGGGCACCCGAGCGCTCCAGATTGCGATGTGTGCCCCTG
TGATGGTGGAGCTGGAGGGGGAGACAGATCCTCTGCTCATTGCCATGAAGGAACTCAACTGGACCAAGCTGACTGAAAGATTCTTCAAGA
ATACACCTTGGCCCGAGGCTGAAGCCATTGCTCCACAGGTTGGCAATGATGCTGTCTTCCTGATTTTATACAAAGAATTATACTACAGGC
ACATATATGCCAAAGTCAGTGGGGGACCTTCCTTGGAGCAGAGGTTTGAATCCTATTACAACTACTGCAATCTCTTCAACTACATTCTTA
ATGCCGATGGTCCTGCTCCCCTTGAACTACCCAACCAGTGGCTCTGGGATATTATCGATGAGTTCATCTACCAGTTTCAGTCATTCAGTC
AGTACCGCTGTAAGACTGCCAAGAAGTCAGAGGAGGAGATTGACTTTCTTCGTTCCAATCCCAAAATCTGGAATGTTCATAGTGTCCTCA
ATGTCCTTCATTCCCTGGTAGACAAATCCAACATCAACCGACAGTTGGAGGTATACACAAGCGGAGGTGACCCTGAGAGTGTGGCTGGGG
AGTATGGGCGGCACTCCCTCTACAAAATGCTTGGTTACTTCAGCCTGGTCGGGCTTCTCCGCCTGCACTCCCTGTTAGGAGATTACTACC
AGGCCATCAAGGTGCTGGAGAACATCGAACTGAACAAGAAGAGTATGTATTCCCGTGTGCCAGAGTGCCAGGTCACCACATACTATTATG
TTGGGTTTGCATATTTGATGATGCGTCGTTACCAGGATGCCATCCGGGTCTTCGCCAACATCCTCCTCTACATCCAGAGGACCAAGAGCA
TGTTCCAGAGGACCACGTACAAGTATGAGATGATTAACAAGCAGAATGAGCAGATGCATGCGCTGCTGGCCATTGCCCTCACGATGTACC
CCATGCGTATTGATGAGAGCATTCACCTCCAGCTGCGGGAGAAATATGGGGACAAGATGTTGCGCATGCAGAAAGGTGACCCACAAGTCT
ATGAAGAACTTTTCAGTTACTCCTGCCCCAAGTTCCTGTCGCCTGTAGTGCCCAACTATGATAATGTGCACCCCAACTACCACAAAGAGC
CCTTCCTGCAGCAGCTGAAGGTGTTTTCTGATGAAGTACAGCAGCAGGCCCAGCTTTCAACCATCCGCAGCTTCCTGAAGCTCTACACCA
CCATGCCTGTGGCCAAGCTGGCTGGCTTCCTGGACCTCACAGAGCAGGAGTTCCGGATCCAGCTTCTTGTCTTCAAACACAAGATGAAGA
ACCTCGTGTGGACCAGCGGTATCTCAGCCCTGGATGGTGAATTTCAGTCAGCCTCAGAGGTTGACTTCTACATTGATAAGGACATGATCC
ACATCGCGGACACCAAGGTCGCCAGGCGTTATGGGGATTTCTTCATCCGTCAGATCCACAAATTTGAGGAGCTTAATCGAACCCTGAAGA
AGATGGGACAGAGACCTTGATGATATTCACACACATTCAGGAACCTGTTTTGATGTATTATAGGCAGGAAGTGTTTTTGCTACCGTGAAA
CCTTTACCTAGATCAGCCATCAGCCTGTCAACTCAGTTAACAAGTTAAGGACCGAAGTGTTTCAAGTGGATCTCAGTAAAGGATCTTTGG
AGCCAGATTTGTCGTCTCATTATTGTAGGAGAGAATTTGTGGGTTGTGGCAGTAATACATTTCCCATGTGTCCTGATGCTTTCAGGATAC
ATCAGTTGTTAGTGTTTAAATTGAGTTATTTTTATTTTGTGCTTTTGAGATGGAGTCTCACTCTGTCTCCCAGGCTGGAGTGCAGTAGCG
TGATCTCAGTTCGTTGCATCCTCCGCTGCCCAGGTTCAAGCAGTTCTGCCTCAGCCTTCCAAGTAGCTGGGATTACAGGCGTGTGCCACC
ACACTCAGCTAATTTTTGTATTCTCAGTAGAGATGGGTTTTACCATGTTGGCCAGGCTGGTCTCGAACTCCTGGCCTCAAGTGATTCGCC
TGCCTTGGCCTCCCAAAATGTGCTAGGATTACAGGCATGAGCCACCACGCCCCGCCTAAATTCAAAATCTTTTTGTTTTTTTTTAGACGG
AGTCTCACTCTGTCGCCCAGGTTGGAGTGTACTGGCGCGATCTCGGCTCACTGCAAGCTCCACCTCCCAGGTTCCTGCCATTCTCCTGCC
TCAGCCTCCCAAGTAGCTGGGACTACAGGCACCCGCCACCATGCCCGGCCAATTTTTTGTATTTTTTAGTAGAGATGGGGTTTCACCGTG
TTAGCCAGGATGGTCTCAGATTTCCTGACCTCGTGATCTGCCCATCTCTGCCTCCTAAAGTACTGGGATTACAGGCGTGAGCCACCGTGC

>67031_67031_6_POLR2F-EIF3L_POLR2F_chr22_38363177_ENST00000442738_EIF3L_chr22_38251572_ENST00000412331_length(amino acids)=564AA_BP=98
MSDNEDNFDGDDFDDVEEDEGLDDLENAEEEGQENVEILPSGERPQANQKRITTPYMTKYERARVLGTRALQIAMCAPVMVELEGETDPL
LIAMKELNWTKLTERFFKNTPWPEAEAIAPQVGNDAVFLILYKELYYRHIYAKVSGGPSLEQRFESYYNYCNLFNYILNADGPAPLELPN
QWLWDIIDEFIYQFQSFSQYRCKTAKKSEEEIDFLRSNPKIWNVHSVLNVLHSLVDKSNINRQLEVYTSGGDPESVAGEYGRHSLYKMLG
YFSLVGLLRLHSLLGDYYQAIKVLENIELNKKSMYSRVPECQVTTYYYVGFAYLMMRRYQDAIRVFANILLYIQRTKSMFQRTTYKYEMI
NKQNEQMHALLAIALTMYPMRIDESIHLQLREKYGDKMLRMQKGDPQVYEELFSYSCPKFLSPVVPNYDNVHPNYHKEPFLQQLKVFSDE
VQQQAQLSTIRSFLKLYTTMPVAKLAGFLDLTEQEFRIQLLVFKHKMKNLVWTSGISALDGEFQSASEVDFYIDKDMIHIADTKVARRYG

--------------------------------------------------------------
>67031_67031_7_POLR2F-EIF3L_POLR2F_chr22_38363177_ENST00000470701_EIF3L_chr22_38251572_ENST00000381683_length(transcript)=1680nt_BP=407nt
CGCTGTTTGCGGGTCTCCGCGCGGGACCGGGGCGCAGCGGGGTCGCTGAGGCGAGGGTGTCATGTCAGACAACGAGGACAAGTGAGTGCG
GGAGCGGAGTGGCCTTTGCGGCAACCTTGGAAGGGGCGGATGAGTTTTGATGGCGACGACTTTGATGATGTGGAGGAGGATGAAGGGCTA
GATGACTTGGAGAATGCCGAAGAGGAAGGCCAGGAGAATGTCGAGATCCTCCCCTCTGGGGAGCGACCGCAGGCCAACCAGAAGCGAATC
ACCACACCATACATGACCAAGTACGAGCGAGCCCGCGTGCTGGGCACCCGAGCGCTCCAGATTGCGATGTGTGCCCCTGTGATGGTGGAG
CTGGAGGGGGAGACAGATCCTCTGCTCATTGCCATGAAGGAACTCAACTGGACCAAGCTGACTGAAAGATTCTTCAAGAATACACCTTGG
CCCGAGGCTGAAGCCATTGCTCCACAGGTTGGCAATGATGCTGTCTTCCTGATTTTATACAAAGAATTATACTACAGGCACATATATGCC
AAAGTCAGTTTTCAGTCATTCAGTCAGTACCGCTGTAAGACTGCCAAGAAGTCAGAGGAGGAGATTGACTTTCTTCGTTCCAATCCCAAA
ATCTGGAATGTTCATAGTGTCCTCAATGTCCTTCATTCCCTGGTAGACAAATCCAACATCAACCGACAGTTGGAGGTATACACAAGCGGA
GGTGACCCTGAGAGTGTGGCTGGGGAGTATGGGCGGCACTCCCTCTACAAAATGCTTGGTTACTTCAGCCTGGTCGGGCTTCTCCGCCTG
CACTCCCTGTTAGGAGATTACTACCAGGCCATCAAGGTGCTGGAGAACATCGAACTGAACAAGAAGAGTATGTATTCCCGTGTGCCAGAG
TGCCAGGTCACCACATACTATTATGTTGGGTTTGCATATTTGATGATGCGTCGTTACCAGGATGCCATCCGGGTCTTCGCCAACATCCTC
CTCTACATCCAGAGGACCAAGAGCATGTTCCAGAGGACCACGTACAAGTATGAGATGATTAACAAGCAGAATGAGCAGATGCATGCGCTG
CTGGCCATTGCCCTCACGATGTACCCCATGCGTATTGATGAGAGCATTCACCTCCAGCTGCGGGAGAAATATGGGGACAAGATGTTGCGC
ATGCAGAAAGGTGACCCACAAGTCTATGAAGAACTTTTCAGTTACTCCTGCCCCAAGTTCCTGTCGCCTGTAGTGCCCAACTATGATAAT
GTGCACCCCAACTACCACAAAGAGCCCTTCCTGCAGCAGCTGAAGGTGTTTTCTGATGAAGTACAGCAGCAGGCCCAGCTTTCAACCATC
CGCAGCTTCCTGAAGCTCTACACCACCATGCCTGTGGCCAAGCTGGCTGGCTTCCTGGACCTCACAGAGCAGGAGTTCCGGATCCAGCTT
CTTGTCTTCAAACACAAGATGAAGAACCTCGTGTGGACCAGCGGTATCTCAGCCCTGGATGGTGAATTTCAGTCAGCCTCAGAGGTTGAC
TTCTACATTGATAAGGACATGATCCACATCGCGGACACCAAGGTCGCCAGGCGTTATGGGGATTTCTTCATCCGTCAGATCCACAAATTT

>67031_67031_7_POLR2F-EIF3L_POLR2F_chr22_38363177_ENST00000470701_EIF3L_chr22_38251572_ENST00000381683_length(amino acids)=552AA_BP=134
MRVSARDRGAAGSLRRGCHVRQRGQVSAGAEWPLRQPWKGRMSFDGDDFDDVEEDEGLDDLENAEEEGQENVEILPSGERPQANQKRITT
PYMTKYERARVLGTRALQIAMCAPVMVELEGETDPLLIAMKELNWTKLTERFFKNTPWPEAEAIAPQVGNDAVFLILYKELYYRHIYAKV
SFQSFSQYRCKTAKKSEEEIDFLRSNPKIWNVHSVLNVLHSLVDKSNINRQLEVYTSGGDPESVAGEYGRHSLYKMLGYFSLVGLLRLHS
LLGDYYQAIKVLENIELNKKSMYSRVPECQVTTYYYVGFAYLMMRRYQDAIRVFANILLYIQRTKSMFQRTTYKYEMINKQNEQMHALLA
IALTMYPMRIDESIHLQLREKYGDKMLRMQKGDPQVYEELFSYSCPKFLSPVVPNYDNVHPNYHKEPFLQQLKVFSDEVQQQAQLSTIRS
FLKLYTTMPVAKLAGFLDLTEQEFRIQLLVFKHKMKNLVWTSGISALDGEFQSASEVDFYIDKDMIHIADTKVARRYGDFFIRQIHKFEE

--------------------------------------------------------------
>67031_67031_8_POLR2F-EIF3L_POLR2F_chr22_38363177_ENST00000470701_EIF3L_chr22_38251572_ENST00000412331_length(transcript)=2752nt_BP=407nt
CGCTGTTTGCGGGTCTCCGCGCGGGACCGGGGCGCAGCGGGGTCGCTGAGGCGAGGGTGTCATGTCAGACAACGAGGACAAGTGAGTGCG
GGAGCGGAGTGGCCTTTGCGGCAACCTTGGAAGGGGCGGATGAGTTTTGATGGCGACGACTTTGATGATGTGGAGGAGGATGAAGGGCTA
GATGACTTGGAGAATGCCGAAGAGGAAGGCCAGGAGAATGTCGAGATCCTCCCCTCTGGGGAGCGACCGCAGGCCAACCAGAAGCGAATC
ACCACACCATACATGACCAAGTACGAGCGAGCCCGCGTGCTGGGCACCCGAGCGCTCCAGATTGCGATGTGTGCCCCTGTGATGGTGGAG
CTGGAGGGGGAGACAGATCCTCTGCTCATTGCCATGAAGGAACTCAACTGGACCAAGCTGACTGAAAGATTCTTCAAGAATACACCTTGG
CCCGAGGCTGAAGCCATTGCTCCACAGGTTGGCAATGATGCTGTCTTCCTGATTTTATACAAAGAATTATACTACAGGCACATATATGCC
AAAGTCAGTGGGGGACCTTCCTTGGAGCAGAGGTTTGAATCCTATTACAACTACTGCAATCTCTTCAACTACATTCTTAATGCCGATGGT
CCTGCTCCCCTTGAACTACCCAACCAGTGGCTCTGGGATATTATCGATGAGTTCATCTACCAGTTTCAGTCATTCAGTCAGTACCGCTGT
AAGACTGCCAAGAAGTCAGAGGAGGAGATTGACTTTCTTCGTTCCAATCCCAAAATCTGGAATGTTCATAGTGTCCTCAATGTCCTTCAT
TCCCTGGTAGACAAATCCAACATCAACCGACAGTTGGAGGTATACACAAGCGGAGGTGACCCTGAGAGTGTGGCTGGGGAGTATGGGCGG
CACTCCCTCTACAAAATGCTTGGTTACTTCAGCCTGGTCGGGCTTCTCCGCCTGCACTCCCTGTTAGGAGATTACTACCAGGCCATCAAG
GTGCTGGAGAACATCGAACTGAACAAGAAGAGTATGTATTCCCGTGTGCCAGAGTGCCAGGTCACCACATACTATTATGTTGGGTTTGCA
TATTTGATGATGCGTCGTTACCAGGATGCCATCCGGGTCTTCGCCAACATCCTCCTCTACATCCAGAGGACCAAGAGCATGTTCCAGAGG
ACCACGTACAAGTATGAGATGATTAACAAGCAGAATGAGCAGATGCATGCGCTGCTGGCCATTGCCCTCACGATGTACCCCATGCGTATT
GATGAGAGCATTCACCTCCAGCTGCGGGAGAAATATGGGGACAAGATGTTGCGCATGCAGAAAGGTGACCCACAAGTCTATGAAGAACTT
TTCAGTTACTCCTGCCCCAAGTTCCTGTCGCCTGTAGTGCCCAACTATGATAATGTGCACCCCAACTACCACAAAGAGCCCTTCCTGCAG
CAGCTGAAGGTGTTTTCTGATGAAGTACAGCAGCAGGCCCAGCTTTCAACCATCCGCAGCTTCCTGAAGCTCTACACCACCATGCCTGTG
GCCAAGCTGGCTGGCTTCCTGGACCTCACAGAGCAGGAGTTCCGGATCCAGCTTCTTGTCTTCAAACACAAGATGAAGAACCTCGTGTGG
ACCAGCGGTATCTCAGCCCTGGATGGTGAATTTCAGTCAGCCTCAGAGGTTGACTTCTACATTGATAAGGACATGATCCACATCGCGGAC
ACCAAGGTCGCCAGGCGTTATGGGGATTTCTTCATCCGTCAGATCCACAAATTTGAGGAGCTTAATCGAACCCTGAAGAAGATGGGACAG
AGACCTTGATGATATTCACACACATTCAGGAACCTGTTTTGATGTATTATAGGCAGGAAGTGTTTTTGCTACCGTGAAACCTTTACCTAG
ATCAGCCATCAGCCTGTCAACTCAGTTAACAAGTTAAGGACCGAAGTGTTTCAAGTGGATCTCAGTAAAGGATCTTTGGAGCCAGATTTG
TCGTCTCATTATTGTAGGAGAGAATTTGTGGGTTGTGGCAGTAATACATTTCCCATGTGTCCTGATGCTTTCAGGATACATCAGTTGTTA
GTGTTTAAATTGAGTTATTTTTATTTTGTGCTTTTGAGATGGAGTCTCACTCTGTCTCCCAGGCTGGAGTGCAGTAGCGTGATCTCAGTT
CGTTGCATCCTCCGCTGCCCAGGTTCAAGCAGTTCTGCCTCAGCCTTCCAAGTAGCTGGGATTACAGGCGTGTGCCACCACACTCAGCTA
ATTTTTGTATTCTCAGTAGAGATGGGTTTTACCATGTTGGCCAGGCTGGTCTCGAACTCCTGGCCTCAAGTGATTCGCCTGCCTTGGCCT
CCCAAAATGTGCTAGGATTACAGGCATGAGCCACCACGCCCCGCCTAAATTCAAAATCTTTTTGTTTTTTTTTAGACGGAGTCTCACTCT
GTCGCCCAGGTTGGAGTGTACTGGCGCGATCTCGGCTCACTGCAAGCTCCACCTCCCAGGTTCCTGCCATTCTCCTGCCTCAGCCTCCCA
AGTAGCTGGGACTACAGGCACCCGCCACCATGCCCGGCCAATTTTTTGTATTTTTTAGTAGAGATGGGGTTTCACCGTGTTAGCCAGGAT
GGTCTCAGATTTCCTGACCTCGTGATCTGCCCATCTCTGCCTCCTAAAGTACTGGGATTACAGGCGTGAGCCACCGTGCCCAGCCCTAAA

>67031_67031_8_POLR2F-EIF3L_POLR2F_chr22_38363177_ENST00000470701_EIF3L_chr22_38251572_ENST00000412331_length(amino acids)=600AA_BP=134
MRVSARDRGAAGSLRRGCHVRQRGQVSAGAEWPLRQPWKGRMSFDGDDFDDVEEDEGLDDLENAEEEGQENVEILPSGERPQANQKRITT
PYMTKYERARVLGTRALQIAMCAPVMVELEGETDPLLIAMKELNWTKLTERFFKNTPWPEAEAIAPQVGNDAVFLILYKELYYRHIYAKV
SGGPSLEQRFESYYNYCNLFNYILNADGPAPLELPNQWLWDIIDEFIYQFQSFSQYRCKTAKKSEEEIDFLRSNPKIWNVHSVLNVLHSL
VDKSNINRQLEVYTSGGDPESVAGEYGRHSLYKMLGYFSLVGLLRLHSLLGDYYQAIKVLENIELNKKSMYSRVPECQVTTYYYVGFAYL
MMRRYQDAIRVFANILLYIQRTKSMFQRTTYKYEMINKQNEQMHALLAIALTMYPMRIDESIHLQLREKYGDKMLRMQKGDPQVYEELFS
YSCPKFLSPVVPNYDNVHPNYHKEPFLQQLKVFSDEVQQQAQLSTIRSFLKLYTTMPVAKLAGFLDLTEQEFRIQLLVFKHKMKNLVWTS

--------------------------------------------------------------
>67031_67031_9_POLR2F-EIF3L_POLR2F_chr22_38363177_ENST00000606538_EIF3L_chr22_38251572_ENST00000381683_length(transcript)=1961nt_BP=688nt
GCGCGAGTCGTAGTGTCGCTGTTTGCGGGTCTCCGCGCGGGACCGGGGCGCAGCGGGGTCGCTGAGGCGAGGGTGTCATGTCAGACAACG
AGGACAATTTTGATGGCGACGACTTTGATGATGTGGAGGAGGATGAAGGGCTAGATGACTTGGAGAATGCCGAAGAGGAAGGCCAGGAGA
ATGTCGAGATCCTCCCCTCTGGGGAGCGACCGCAGGCCAACCAGAAGCGAATCACCACACCATACATGACCAAGTACGAGCGAGCCCGCG
TGCTGGGCACCCGAGCGCTCCAGATTGCGTAAGTCACTCAAATCATGGTTCACTTCTCCAAATCTCTGGGAGGCATCTGTTGGGCTCTCT
GTTGCACCCTTTGCTCCCACTTGCCTGGCTGGAGAAGTTGATGCTTATTCCTACAGATCCTTAGGAACAGCTCACCAGGAAGTAGGAGGA
AGAGAGAAGAGGAGGCAGGGAAAGTGGGAGGGCACTGATGAGACATGGACGTCTTCTGGCTGTTGGAATTTCCCTGTTCCTGCTGCAGGA
GGCCTTACCAATATTCTGTCATTCTTCCCCCTCTTGTCTGATATAAAAACTTTCTTTTTCTTGTAATTGCTTTCTTACAAAGTACACTCA
TCAGCCCCAAGAGGCTGCTCCTAAGACTTCTCTTTGCTTGTGTTTTGCACACAATCTGCTGGACCAAGCTGACTGAAAGATTCTTCAAGA
ATACACCTTGGCCCGAGGCTGAAGCCATTGCTCCACAGGTTGGCAATGATGCTGTCTTCCTGATTTTATACAAAGAATTATACTACAGGC
ACATATATGCCAAAGTCAGTTTTCAGTCATTCAGTCAGTACCGCTGTAAGACTGCCAAGAAGTCAGAGGAGGAGATTGACTTTCTTCGTT
CCAATCCCAAAATCTGGAATGTTCATAGTGTCCTCAATGTCCTTCATTCCCTGGTAGACAAATCCAACATCAACCGACAGTTGGAGGTAT
ACACAAGCGGAGGTGACCCTGAGAGTGTGGCTGGGGAGTATGGGCGGCACTCCCTCTACAAAATGCTTGGTTACTTCAGCCTGGTCGGGC
TTCTCCGCCTGCACTCCCTGTTAGGAGATTACTACCAGGCCATCAAGGTGCTGGAGAACATCGAACTGAACAAGAAGAGTATGTATTCCC
GTGTGCCAGAGTGCCAGGTCACCACATACTATTATGTTGGGTTTGCATATTTGATGATGCGTCGTTACCAGGATGCCATCCGGGTCTTCG
CCAACATCCTCCTCTACATCCAGAGGACCAAGAGCATGTTCCAGAGGACCACGTACAAGTATGAGATGATTAACAAGCAGAATGAGCAGA
TGCATGCGCTGCTGGCCATTGCCCTCACGATGTACCCCATGCGTATTGATGAGAGCATTCACCTCCAGCTGCGGGAGAAATATGGGGACA
AGATGTTGCGCATGCAGAAAGGTGACCCACAAGTCTATGAAGAACTTTTCAGTTACTCCTGCCCCAAGTTCCTGTCGCCTGTAGTGCCCA
ACTATGATAATGTGCACCCCAACTACCACAAAGAGCCCTTCCTGCAGCAGCTGAAGGTGTTTTCTGATGAAGTACAGCAGCAGGCCCAGC
TTTCAACCATCCGCAGCTTCCTGAAGCTCTACACCACCATGCCTGTGGCCAAGCTGGCTGGCTTCCTGGACCTCACAGAGCAGGAGTTCC
GGATCCAGCTTCTTGTCTTCAAACACAAGATGAAGAACCTCGTGTGGACCAGCGGTATCTCAGCCCTGGATGGTGAATTTCAGTCAGCCT
CAGAGGTTGACTTCTACATTGATAAGGACATGATCCACATCGCGGACACCAAGGTCGCCAGGCGTTATGGGGATTTCTTCATCCGTCAGA

>67031_67031_9_POLR2F-EIF3L_POLR2F_chr22_38363177_ENST00000606538_EIF3L_chr22_38251572_ENST00000381683_length(amino acids)=433AA_BP=15
MLLRLLFACVLHTICWTKLTERFFKNTPWPEAEAIAPQVGNDAVFLILYKELYYRHIYAKVSFQSFSQYRCKTAKKSEEEIDFLRSNPKI
WNVHSVLNVLHSLVDKSNINRQLEVYTSGGDPESVAGEYGRHSLYKMLGYFSLVGLLRLHSLLGDYYQAIKVLENIELNKKSMYSRVPEC
QVTTYYYVGFAYLMMRRYQDAIRVFANILLYIQRTKSMFQRTTYKYEMINKQNEQMHALLAIALTMYPMRIDESIHLQLREKYGDKMLRM
QKGDPQVYEELFSYSCPKFLSPVVPNYDNVHPNYHKEPFLQQLKVFSDEVQQQAQLSTIRSFLKLYTTMPVAKLAGFLDLTEQEFRIQLL

--------------------------------------------------------------
>67031_67031_10_POLR2F-EIF3L_POLR2F_chr22_38363177_ENST00000606538_EIF3L_chr22_38251572_ENST00000412331_length(transcript)=3033nt_BP=688nt
GCGCGAGTCGTAGTGTCGCTGTTTGCGGGTCTCCGCGCGGGACCGGGGCGCAGCGGGGTCGCTGAGGCGAGGGTGTCATGTCAGACAACG
AGGACAATTTTGATGGCGACGACTTTGATGATGTGGAGGAGGATGAAGGGCTAGATGACTTGGAGAATGCCGAAGAGGAAGGCCAGGAGA
ATGTCGAGATCCTCCCCTCTGGGGAGCGACCGCAGGCCAACCAGAAGCGAATCACCACACCATACATGACCAAGTACGAGCGAGCCCGCG
TGCTGGGCACCCGAGCGCTCCAGATTGCGTAAGTCACTCAAATCATGGTTCACTTCTCCAAATCTCTGGGAGGCATCTGTTGGGCTCTCT
GTTGCACCCTTTGCTCCCACTTGCCTGGCTGGAGAAGTTGATGCTTATTCCTACAGATCCTTAGGAACAGCTCACCAGGAAGTAGGAGGA
AGAGAGAAGAGGAGGCAGGGAAAGTGGGAGGGCACTGATGAGACATGGACGTCTTCTGGCTGTTGGAATTTCCCTGTTCCTGCTGCAGGA
GGCCTTACCAATATTCTGTCATTCTTCCCCCTCTTGTCTGATATAAAAACTTTCTTTTTCTTGTAATTGCTTTCTTACAAAGTACACTCA
TCAGCCCCAAGAGGCTGCTCCTAAGACTTCTCTTTGCTTGTGTTTTGCACACAATCTGCTGGACCAAGCTGACTGAAAGATTCTTCAAGA
ATACACCTTGGCCCGAGGCTGAAGCCATTGCTCCACAGGTTGGCAATGATGCTGTCTTCCTGATTTTATACAAAGAATTATACTACAGGC
ACATATATGCCAAAGTCAGTGGGGGACCTTCCTTGGAGCAGAGGTTTGAATCCTATTACAACTACTGCAATCTCTTCAACTACATTCTTA
ATGCCGATGGTCCTGCTCCCCTTGAACTACCCAACCAGTGGCTCTGGGATATTATCGATGAGTTCATCTACCAGTTTCAGTCATTCAGTC
AGTACCGCTGTAAGACTGCCAAGAAGTCAGAGGAGGAGATTGACTTTCTTCGTTCCAATCCCAAAATCTGGAATGTTCATAGTGTCCTCA
ATGTCCTTCATTCCCTGGTAGACAAATCCAACATCAACCGACAGTTGGAGGTATACACAAGCGGAGGTGACCCTGAGAGTGTGGCTGGGG
AGTATGGGCGGCACTCCCTCTACAAAATGCTTGGTTACTTCAGCCTGGTCGGGCTTCTCCGCCTGCACTCCCTGTTAGGAGATTACTACC
AGGCCATCAAGGTGCTGGAGAACATCGAACTGAACAAGAAGAGTATGTATTCCCGTGTGCCAGAGTGCCAGGTCACCACATACTATTATG
TTGGGTTTGCATATTTGATGATGCGTCGTTACCAGGATGCCATCCGGGTCTTCGCCAACATCCTCCTCTACATCCAGAGGACCAAGAGCA
TGTTCCAGAGGACCACGTACAAGTATGAGATGATTAACAAGCAGAATGAGCAGATGCATGCGCTGCTGGCCATTGCCCTCACGATGTACC
CCATGCGTATTGATGAGAGCATTCACCTCCAGCTGCGGGAGAAATATGGGGACAAGATGTTGCGCATGCAGAAAGGTGACCCACAAGTCT
ATGAAGAACTTTTCAGTTACTCCTGCCCCAAGTTCCTGTCGCCTGTAGTGCCCAACTATGATAATGTGCACCCCAACTACCACAAAGAGC
CCTTCCTGCAGCAGCTGAAGGTGTTTTCTGATGAAGTACAGCAGCAGGCCCAGCTTTCAACCATCCGCAGCTTCCTGAAGCTCTACACCA
CCATGCCTGTGGCCAAGCTGGCTGGCTTCCTGGACCTCACAGAGCAGGAGTTCCGGATCCAGCTTCTTGTCTTCAAACACAAGATGAAGA
ACCTCGTGTGGACCAGCGGTATCTCAGCCCTGGATGGTGAATTTCAGTCAGCCTCAGAGGTTGACTTCTACATTGATAAGGACATGATCC
ACATCGCGGACACCAAGGTCGCCAGGCGTTATGGGGATTTCTTCATCCGTCAGATCCACAAATTTGAGGAGCTTAATCGAACCCTGAAGA
AGATGGGACAGAGACCTTGATGATATTCACACACATTCAGGAACCTGTTTTGATGTATTATAGGCAGGAAGTGTTTTTGCTACCGTGAAA
CCTTTACCTAGATCAGCCATCAGCCTGTCAACTCAGTTAACAAGTTAAGGACCGAAGTGTTTCAAGTGGATCTCAGTAAAGGATCTTTGG
AGCCAGATTTGTCGTCTCATTATTGTAGGAGAGAATTTGTGGGTTGTGGCAGTAATACATTTCCCATGTGTCCTGATGCTTTCAGGATAC
ATCAGTTGTTAGTGTTTAAATTGAGTTATTTTTATTTTGTGCTTTTGAGATGGAGTCTCACTCTGTCTCCCAGGCTGGAGTGCAGTAGCG
TGATCTCAGTTCGTTGCATCCTCCGCTGCCCAGGTTCAAGCAGTTCTGCCTCAGCCTTCCAAGTAGCTGGGATTACAGGCGTGTGCCACC
ACACTCAGCTAATTTTTGTATTCTCAGTAGAGATGGGTTTTACCATGTTGGCCAGGCTGGTCTCGAACTCCTGGCCTCAAGTGATTCGCC
TGCCTTGGCCTCCCAAAATGTGCTAGGATTACAGGCATGAGCCACCACGCCCCGCCTAAATTCAAAATCTTTTTGTTTTTTTTTAGACGG
AGTCTCACTCTGTCGCCCAGGTTGGAGTGTACTGGCGCGATCTCGGCTCACTGCAAGCTCCACCTCCCAGGTTCCTGCCATTCTCCTGCC
TCAGCCTCCCAAGTAGCTGGGACTACAGGCACCCGCCACCATGCCCGGCCAATTTTTTGTATTTTTTAGTAGAGATGGGGTTTCACCGTG
TTAGCCAGGATGGTCTCAGATTTCCTGACCTCGTGATCTGCCCATCTCTGCCTCCTAAAGTACTGGGATTACAGGCGTGAGCCACCGTGC

>67031_67031_10_POLR2F-EIF3L_POLR2F_chr22_38363177_ENST00000606538_EIF3L_chr22_38251572_ENST00000412331_length(amino acids)=481AA_BP=15
MLLRLLFACVLHTICWTKLTERFFKNTPWPEAEAIAPQVGNDAVFLILYKELYYRHIYAKVSGGPSLEQRFESYYNYCNLFNYILNADGP
APLELPNQWLWDIIDEFIYQFQSFSQYRCKTAKKSEEEIDFLRSNPKIWNVHSVLNVLHSLVDKSNINRQLEVYTSGGDPESVAGEYGRH
SLYKMLGYFSLVGLLRLHSLLGDYYQAIKVLENIELNKKSMYSRVPECQVTTYYYVGFAYLMMRRYQDAIRVFANILLYIQRTKSMFQRT
TYKYEMINKQNEQMHALLAIALTMYPMRIDESIHLQLREKYGDKMLRMQKGDPQVYEELFSYSCPKFLSPVVPNYDNVHPNYHKEPFLQQ
LKVFSDEVQQQAQLSTIRSFLKLYTTMPVAKLAGFLDLTEQEFRIQLLVFKHKMKNLVWTSGISALDGEFQSASEVDFYIDKDMIHIADT

--------------------------------------------------------------

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Fusion Gene PPI Analysis for POLR2F-EIF3L


check button Go to ChiPPI (Chimeric Protein-Protein interactions) to see the chimeric PPI interaction in

ChiPPI page.


check button Protein-protein interactors with each fusion partner protein in wild-type (BIOGRID-3.4.160)
HgeneHgene's interactorsTgeneTgene's interactors


check button - Retained PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenStill interaction with


check button - Lost PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


check button - Retained PPIs, but lost function due to frame-shift fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


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Related Drugs for POLR2F-EIF3L


check button Drugs targeting genes involved in this fusion gene.
(DrugBank Version 5.1.8 2021-05-08)
PartnerGeneUniProtAccDrugBank IDDrug nameDrug activityDrug typeDrug status

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Related Diseases for POLR2F-EIF3L


check button Diseases associated with fusion partners.
(DisGeNet 4.0)
PartnerGeneDisease IDDisease name# pubmedsSource