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 | Fusion Gene Summary |
| Fusion Gene ORF analysis |
| Fusion Genomic Features |
| Fusion Protein Features |
| Fusion Gene Sequence |
| Fusion Gene PPI analysis |
| Related Drugs |
| Related Diseases |
Fusion gene:POM121C-HIP1 (FusionGDB2 ID:67128) |
Fusion Gene Summary for POM121C-HIP1 |
 Fusion gene summary |
| Fusion gene information | Fusion gene name: POM121C-HIP1 | Fusion gene ID: 67128 | Hgene | Tgene | Gene symbol | POM121C | HIP1 | Gene ID | 100101267 | 3092 |
| Gene name | POM121 transmembrane nucleoporin C | huntingtin interacting protein 1 | |
| Synonyms | POM121-2 | HIP-I|ILWEQ|SHON|SHONbeta|SHONgamma | |
| Cytomap | 7q11.23 | 7q11.23 | |
| Type of gene | protein-coding | protein-coding | |
| Description | nuclear envelope pore membrane protein POM 121CPOM121 membrane glycoprotein Cnuclear pore membrane protein 121-2pore membrane protein of 121 kDa C | huntingtin-interacting protein 1huntingtin-interacting protein I | |
| Modification date | 20200313 | 20200313 | |
| UniProtAcc | . | O75146 | |
| Ensembl transtripts involved in fusion gene | ENST00000257665, ENST00000453279, ENST00000473168, | ENST00000479835, ENST00000336926, ENST00000434438, | |
| Fusion gene scores | * DoF score | 8 X 7 X 6=336 | 9 X 9 X 5=405 |
| # samples | 8 | 9 | |
| ** MAII score | log2(8/336*10)=-2.0703893278914 possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs). DoF>8 and MAII<0 | log2(9/405*10)=-2.16992500144231 possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs). DoF>8 and MAII<0 | |
| Context | PubMed: POM121C [Title/Abstract] AND HIP1 [Title/Abstract] AND fusion [Title/Abstract] | ||
| Most frequent breakpoint | POM121C(75066793)-HIP1(75228565), # samples:2 | ||
| Anticipated loss of major functional domain due to fusion event. | POM121C-HIP1 seems lost the major protein functional domain in Tgene partner, which is a CGC due to the frame-shifted ORF. POM121C-HIP1 seems lost the major protein functional domain in Tgene partner, which is a essential gene due to the frame-shifted ORF. | ||
| * DoF score (Degree of Frequency) = # partners X # break points X # cancer types ** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10) |
| Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez |
| Partner | Gene | GO ID | GO term | PubMed ID |
| Tgene | HIP1 | GO:0006915 | apoptotic process | 11788820 |
| Tgene | HIP1 | GO:0006919 | activation of cysteine-type endopeptidase activity involved in apoptotic process | 11788820 |
| Tgene | HIP1 | GO:0042981 | regulation of apoptotic process | 11788820 |
| Tgene | HIP1 | GO:0048268 | clathrin coat assembly | 11577110|11889126 |
| Tgene | HIP1 | GO:0050821 | protein stabilization | 14732715 |
| Tgene | HIP1 | GO:0097190 | apoptotic signaling pathway | 11007801 |
| Fusion gene breakpoints across POM121C (5'-gene) * Click on the image to open the UCSC genome browser with custom track showing this image in a new window. |
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| Fusion gene breakpoints across HIP1 (3'-gene) * Click on the image to open the UCSC genome browser with custom track showing this image in a new window. |
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| Fusion gene information from two resources (ChiTars 5.0 and ChimerDB 4.0) * All genome coordinats were lifted-over on hg19. * Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser. |
| Source | Disease | Sample | Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand |
| ChimerDB4 | UCS | TCGA-NF-A5CP-01A | POM121C | chr7 | 75066793 | - | HIP1 | chr7 | 75228565 | - |
| ChimerDB4 | UCS | TCGA-NF-A5CP | POM121C | chr7 | 75066793 | - | HIP1 | chr7 | 75228565 | - |
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Fusion Gene ORF analysis for POM121C-HIP1 |
| Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure. * Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser. |
| ORF | Henst | Tenst | Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand |
| 5CDS-intron | ENST00000257665 | ENST00000479835 | POM121C | chr7 | 75066793 | - | HIP1 | chr7 | 75228565 | - |
| 5CDS-intron | ENST00000453279 | ENST00000479835 | POM121C | chr7 | 75066793 | - | HIP1 | chr7 | 75228565 | - |
| 5UTR-3CDS | ENST00000473168 | ENST00000336926 | POM121C | chr7 | 75066793 | - | HIP1 | chr7 | 75228565 | - |
| 5UTR-3CDS | ENST00000473168 | ENST00000434438 | POM121C | chr7 | 75066793 | - | HIP1 | chr7 | 75228565 | - |
| 5UTR-intron | ENST00000473168 | ENST00000479835 | POM121C | chr7 | 75066793 | - | HIP1 | chr7 | 75228565 | - |
| Frame-shift | ENST00000453279 | ENST00000336926 | POM121C | chr7 | 75066793 | - | HIP1 | chr7 | 75228565 | - |
| Frame-shift | ENST00000453279 | ENST00000434438 | POM121C | chr7 | 75066793 | - | HIP1 | chr7 | 75228565 | - |
| In-frame | ENST00000257665 | ENST00000336926 | POM121C | chr7 | 75066793 | - | HIP1 | chr7 | 75228565 | - |
| In-frame | ENST00000257665 | ENST00000434438 | POM121C | chr7 | 75066793 | - | HIP1 | chr7 | 75228565 | - |
| ORFfinder result based on the fusion transcript sequence of in-frame fusion genes. |
| Henst | Tenst | Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand | Seq length (transcript) | BP loci (transcript) | Predicted start (transcript) | Predicted stop (transcript) | Seq length (amino acids) |
| ENST00000257665 | POM121C | chr7 | 75066793 | - | ENST00000336926 | HIP1 | chr7 | 75228565 | - | 9072 | 1206 | 0 | 4199 | 1399 |
| ENST00000257665 | POM121C | chr7 | 75066793 | - | ENST00000434438 | HIP1 | chr7 | 75228565 | - | 8131 | 1206 | 0 | 4046 | 1348 |
| DeepORF prediction of the coding potential based on the fusion transcript sequence of in-frame fusion genes. DeepORF is a coding potential classifier based on convolutional neural network by comparing the real Ribo-seq data. If the no-coding score < 0.5 and coding score > 0.5, then the in-frame fusion transcript is predicted as being likely translated. |
| Henst | Tenst | Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand | No-coding score | Coding score |
| ENST00000257665 | ENST00000336926 | POM121C | chr7 | 75066793 | - | HIP1 | chr7 | 75228565 | - | 0.001450528 | 0.9985494 |
| ENST00000257665 | ENST00000434438 | POM121C | chr7 | 75066793 | - | HIP1 | chr7 | 75228565 | - | 0.002468441 | 0.99753153 |
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Fusion Genomic Features for POM121C-HIP1 |
| FusionAI prediction of the potential fusion gene breakpoint based on the pre-mature RNA sequence context (+/- 5kb of individual partner genes, total 20kb length sequence). FusionAI is a fusion gene breakpoint classifier based on convolutional neural network by comparing the fusion positive and negative sequence context of ~ 20K fusion gene data. From here, we can have the relative potentency of the 20K genomic sequence how individual sequnce will be likely used as the gene fusion breakpoints. |
| Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand | 1-p | p (fusion gene breakpoint) |
| Distribution of 44 human genomic features loci across 20kb length fusion breakpoint regions. We integrated a total of 44 different types of human genomic feature loci information across five big categories including virus integration sites, repeats, structural variants, chromatin states, and gene expression regulation. More details are in help page. |
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| Distribution of 44 human genomic features loci across 20kb length fusion breakpoint regions that are ovelapped with the top 1% feature importance score regions. More details are in help page. |
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Fusion Protein Features for POM121C-HIP1 |
| Four levels of functional features of fusion genes Go to FGviewer search page for the most frequent breakpoint (https://ccsmweb.uth.edu/FGviewer/chr7:75066793/chr7:75228565) - FGviewer provides the online visualization of the retention search of the protein functional features across DNA, RNA, protein, and pathological levels. - How to search 1. Put your fusion gene symbol. 2. Press the tab key until there will be shown the breakpoint information filled. 4. Go down and press 'Search' tab twice. 4. Go down to have the hyperlink of the search result. 5. Click the hyperlink. 6. See the FGviewer result for your fusion gene. |
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| Main function of each fusion partner protein. (from UniProt) |
| Hgene | Tgene |
| . | HIP1 |
| FUNCTION: Transcriptional activator which is required for calcium-dependent dendritic growth and branching in cortical neurons. Recruits CREB-binding protein (CREBBP) to nuclear bodies. Component of the CREST-BRG1 complex, a multiprotein complex that regulates promoter activation by orchestrating a calcium-dependent release of a repressor complex and a recruitment of an activator complex. In resting neurons, transcription of the c-FOS promoter is inhibited by BRG1-dependent recruitment of a phospho-RB1-HDAC1 repressor complex. Upon calcium influx, RB1 is dephosphorylated by calcineurin, which leads to release of the repressor complex. At the same time, there is increased recruitment of CREBBP to the promoter by a CREST-dependent mechanism, which leads to transcriptional activation. The CREST-BRG1 complex also binds to the NR2B promoter, and activity-dependent induction of NR2B expression involves a release of HDAC1 and recruitment of CREBBP (By similarity). {ECO:0000250}. | FUNCTION: Component of clathrin-coated pits and vesicles, that may link the endocytic machinery to the actin cytoskeleton. Binds 3-phosphoinositides (via ENTH domain). May act through the ENTH domain to promote cell survival by stabilizing receptor tyrosine kinases following ligand-induced endocytosis. {ECO:0000269|PubMed:11889126, ECO:0000269|PubMed:14732715}. |
| Retention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at * Minus value of BPloci means that the break pointn is located before the CDS. |
| - In-frame and retained protein feature among the 13 regional features. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Protein feature | Protein feature note |
| Hgene | POM121C | chr7:75066793 | chr7:75228565 | ENST00000257665 | - | 5 | 13 | 131_191 | 402 | 1230.0 | Compositional bias | Note=Pro-rich |
| Hgene | POM121C | chr7:75066793 | chr7:75228565 | ENST00000257665 | - | 5 | 13 | 1_398 | 402 | 1230.0 | Region | Note=Required for targeting to the nucleus and nuclear pore complex |
| Hgene | POM121C | chr7:75066793 | chr7:75228565 | ENST00000257665 | - | 5 | 13 | 1_40 | 402 | 1230.0 | Region | Cisternal side |
| Hgene | POM121C | chr7:75066793 | chr7:75228565 | ENST00000453279 | - | 7 | 15 | 1_40 | 160 | 988.0 | Region | Cisternal side |
| Hgene | POM121C | chr7:75066793 | chr7:75228565 | ENST00000257665 | - | 5 | 13 | 41_61 | 402 | 1230.0 | Transmembrane | Helical |
| Hgene | POM121C | chr7:75066793 | chr7:75228565 | ENST00000453279 | - | 7 | 15 | 41_61 | 160 | 988.0 | Transmembrane | Helical |
| Tgene | HIP1 | chr7:75066793 | chr7:75228565 | ENST00000336926 | 0 | 31 | 368_644 | 40 | 1038.0 | Coiled coil | Ontology_term=ECO:0000255 | |
| Tgene | HIP1 | chr7:75066793 | chr7:75228565 | ENST00000434438 | 0 | 29 | 368_644 | 40 | 987.0 | Coiled coil | Ontology_term=ECO:0000255 | |
| Tgene | HIP1 | chr7:75066793 | chr7:75228565 | ENST00000336926 | 0 | 31 | 771_1012 | 40 | 1038.0 | Domain | I/LWEQ | |
| Tgene | HIP1 | chr7:75066793 | chr7:75228565 | ENST00000434438 | 0 | 29 | 771_1012 | 40 | 987.0 | Domain | I/LWEQ | |
| Tgene | HIP1 | chr7:75066793 | chr7:75228565 | ENST00000336926 | 0 | 31 | 410_491 | 40 | 1038.0 | Region | Note=pDED | |
| Tgene | HIP1 | chr7:75066793 | chr7:75228565 | ENST00000336926 | 0 | 31 | 867_924 | 40 | 1038.0 | Region | Important for actin binding | |
| Tgene | HIP1 | chr7:75066793 | chr7:75228565 | ENST00000434438 | 0 | 29 | 410_491 | 40 | 987.0 | Region | Note=pDED | |
| Tgene | HIP1 | chr7:75066793 | chr7:75228565 | ENST00000434438 | 0 | 29 | 867_924 | 40 | 987.0 | Region | Important for actin binding |
| - In-frame and not-retained protein feature among the 13 regional features. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Protein feature | Protein feature note |
| Hgene | POM121C | chr7:75066793 | chr7:75228565 | ENST00000257665 | - | 5 | 13 | 322_444 | 402 | 1230.0 | Compositional bias | Note=Ser-rich |
| Hgene | POM121C | chr7:75066793 | chr7:75228565 | ENST00000257665 | - | 5 | 13 | 728_924 | 402 | 1230.0 | Compositional bias | Note=Thr-rich |
| Hgene | POM121C | chr7:75066793 | chr7:75228565 | ENST00000453279 | - | 7 | 15 | 131_191 | 160 | 988.0 | Compositional bias | Note=Pro-rich |
| Hgene | POM121C | chr7:75066793 | chr7:75228565 | ENST00000453279 | - | 7 | 15 | 322_444 | 160 | 988.0 | Compositional bias | Note=Ser-rich |
| Hgene | POM121C | chr7:75066793 | chr7:75228565 | ENST00000453279 | - | 7 | 15 | 728_924 | 160 | 988.0 | Compositional bias | Note=Thr-rich |
| Hgene | POM121C | chr7:75066793 | chr7:75228565 | ENST00000257665 | - | 5 | 13 | 62_1229 | 402 | 1230.0 | Region | Pore side |
| Hgene | POM121C | chr7:75066793 | chr7:75228565 | ENST00000453279 | - | 7 | 15 | 1_398 | 160 | 988.0 | Region | Note=Required for targeting to the nucleus and nuclear pore complex |
| Hgene | POM121C | chr7:75066793 | chr7:75228565 | ENST00000453279 | - | 7 | 15 | 62_1229 | 160 | 988.0 | Region | Pore side |
| Tgene | HIP1 | chr7:75066793 | chr7:75228565 | ENST00000336926 | 0 | 31 | 32_160 | 40 | 1038.0 | Domain | ENTH | |
| Tgene | HIP1 | chr7:75066793 | chr7:75228565 | ENST00000434438 | 0 | 29 | 32_160 | 40 | 987.0 | Domain | ENTH |
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Fusion Gene Sequence for POM121C-HIP1 |
| For in-frame fusion transcripts, we provide the fusion transcript sequences and fusion amino acid sequences. To have fusion amino acid sequence, we ran ORFfinder and chose the longest ORF among the all predicted ones. |
| >67128_67128_1_POM121C-HIP1_POM121C_chr7_75066793_ENST00000257665_HIP1_chr7_75228565_ENST00000336926_length(transcript)=9072nt_BP=1206nt ATGTCTCCGGCGGCTGCGGCGGCTGGAGCAGGCGAGCGGCGGCGGCCGATAGCGAGTGTCAGGGACGGCCGGGGCCGGGGCTGCGGCGGG CCGGCCGGGGCGGCGCTTCTCGGCCTGTCGCTGGTCGGCCTCCTACTGTACCTCGTGCCTGCTGCGGCTGCGCTGGCCTGGCTGGCCGTG GGGACTACCGCGGCCTGGTGGGGACTGAGCCGCGAGCCCCGAGGTTCGCGCCCCTTGTCCTCCTTCGTTCAGAAGGCGCGACATCGGCGA ACACTGTTCGCTTCGCCTCCGGCCAAGTCGACAGCCAACGGAAACCTCCTAGAGCCGCGGACCCTGCTCGAAGGACCTGACCCTGCCGAA CTGCTCCTCATGGGCAGTTACCTGGGCAAGCCCGGGCCGCCGCAGCCCGCCCCCGCTCCGGAGGGCCAGGACCTGCGGAATAGGCCTGGC CGCCGCCCACCCGCCCGCCCGGCGCCGCGCTCCACACCGCCCTCCCCGCCGACCCATCGCGTTCACCACTTTTACCCCTCTCTCCCCACT CCTCTTCTCCGACCCTCCGGGAGGCCTTCCCCACGGGATCGTGGGACTTTACCAGATCGGTTTGTAATAACACCTCGAAGACGCTATCCG ATCCATCAGACCCAGTATTCCTGTCCGGGGGTACTTCCCACAGTGTGCTGGAATGGTTATCACAAGAAGGCTGTGCTGTCCCCTCGCAAC TCCAGGATGGTGTGTAGCCCAGTGACTGTGAGGATCGCCCCTCCTGACAGAAGATTTTCACGTTCTGCGATACCAGAGCAGATAATCAGC TCAACACTGTCGTCACCATCAAGTAATGCCCCAGACCCATGTGCAAAGGAGACTGTACTGAGTGCCCTCAAAGAGAAGAAGAAGAAAAGG ACAGTGGAGGAAGAAGACCAAATATTCCTTGATGGCCAGGAAAATAAAAGAAGGCGCCATGATAGCAGTGGCAGTGGACATTCAGCATTT GAGCCCCTGGTGGCCAGTGGAGTCCCCGCTTCTTTTGTGCCTAAGCCTGGGTCTCTGAAGAGAGGCCTCAATTCTCAGAGCTCAGATGAC CACTTGAATAAGAGATCCCGAAGCTCTTCCATGAGCTCCTTGACAGGCGCTTACACAAGTGGCATCCCTAGCTCCAGCCGCAATGCCATT ACCAGTTCCTACAGCTCCACTCGAGGCATCTCACAGACTGTCAGCATCAATAAGGCCATTAATACGCAGGAAGTGGCTGTAAAGGAAAAA CACGCCAGAACGTGCATACTGGGCACCCACCATGAGAAAGGGGCACAGACCTTCTGGTCTGTTGTCAACCGCCTGCCTCTGTCTAGCAAC GCAGTGCTCTGCTGGAAGTTCTGCCATGTGTTCCACAAACTCCTCCGAGATGGACACCCGAACGTCCTGAAGGACTCTCTGAGATACAGA AATGAATTGAGTGACATGAGCAGGATGTGGGGCCACCTGAGCGAGGGGTATGGCCAGCTGTGCAGCATCTACCTGAAACTGCTAAGAACC AAGATGGAGTACCACACCAAAAATCCCAGGTTCCCAGGCAACCTGCAGATGAGTGACCGCCAGCTGGACGAGGCTGGAGAAAGTGACGTG AACAACTTTTTCCAGTTAACAGTGGAGATGTTTGACTACCTGGAGTGTGAACTCAACCTCTTCCAAACAGTATTCAACTCCCTGGACATG TCCCGCTCTGTGTCCGTGACGGCAGCAGGGCAGTGCCGCCTCGCCCCGCTGATCCAGGTCATCTTGGACTGCAGCCACCTTTATGACTAC ACTGTCAAGCTTCTCTTCAAACTCCACTCCTGCCTCCCAGCTGACACCCTGCAAGGCCACCGGGACCGCTTCATGGAGCAGTTTACAAAG TTGAAAGATCTGTTCTACCGCTCCAGCAACCTGCAGTACTTCAAGCGGCTCATTCAGATCCCCCAGCTGCCTGAGAACCCACCCAACTTC CTGCGAGCCTCAGCCCTGTCAGAACATATCAGCCCTGTGGTGGTGATCCCTGCAGAGGCCTCATCCCCCGACAGCGAGCCAGTCCTAGAG AAGGATGACCTCATGGACATGGATGCCTCTCAGCAGAATTTATTTGACAACAAGTTTGATGACATCTTTGGCAGTTCATTCAGCAGTGAT CCCTTCAATTTCAACAGTCAAAATGGTGTGAACAAGGATGAGAAGGACCACTTAATTGAGCGACTATACAGAGAGATCAGTGGATTGAAG GCACAGCTAGAAAACATGAAGACTGAGAGCCAGCGGGTTGTGCTGCAGCTGAAGGGCCACGTCAGCGAGCTGGAAGCAGATCTGGCCGAG CAGCAGCACCTGCGGCAGCAGGCGGCCGACGACTGTGAATTCCTGCGGGCAGAACTGGACGAGCTCAGGAGGCAGCGGGAGGACACCGAG AAGGCTCAGCGGAGCCTGTCTGAGATAGAAAGGAAAGCTCAAGCCAATGAACAGCGATATAGCAAGCTAAAGGAGAAGTACAGCGAGCTG GTTCAGAACCACGCTGACCTGCTGCGGAAGAATGCAGAGGTGACCAAACAGGTGTCCATGGCCAGACAAGCCCAGGTAGATTTGGAACGA GAGAAAAAAGAGCTGGAGGATTCGTTGGAGCGCATCAGTGACCAGGGCCAGCGGAAGACTCAAGAACAGCTGGAAGTTCTAGAGAGCTTG AAGCAGGAACTTGCCACAAGCCAACGGGAGCTTCAGGTTCTGCAAGGCAGCCTGGAAACTTCTGCCCAGTCAGAAGCAAACTGGGCAGCC GAGTTCGCCGAGCTAGAGAAGGAGCGGGACAGCCTGGTGAGTGGCGCAGCTCATAGGGAGGAGGAATTATCTGCTCTTCGGAAAGAACTG CAGGACACTCAGCTCAAACTGGCCAGCACAGAGGAATCTATGTGCCAGCTTGCCAAAGACCAACGAAAAATGCTTCTGGTGGGGTCCAGG AAGGCTGCGGAGCAGGTGATACAAGACGCCCTGAACCAGCTTGAAGAACCTCCTCTCATCAGCTGCGCTGGGTCTGCAGATCACCTCCTC TCCACGGTCACATCCATTTCCAGCTGCATCGAGCAACTGGAGAAAAGCTGGAGCCAGTATCTGGCCTGCCCAGAAGACATCAGTGGACTT CTCCATTCCATAACCCTGCTGGCCCACTTGACCAGCGACGCCATTGCTCATGGTGCCACCACCTGCCTCAGAGCCCCACCTGAGCCTGCC GACTCACTGACCGAGGCCTGTAAGCAGTATGGCAGGGAAACCCTCGCCTACCTGGCCTCCCTGGAGGAAGAGGGAAGCCTTGAGAATGCC GACAGCACAGCCATGAGGAACTGCCTGAGCAAGATCAAGGCCATCGGCGAGGAGCTCCTGCCCAGGGGACTGGACATCAAGCAGGAGGAG CTGGGGGACCTGGTGGACAAGGAGATGGCGGCCACTTCAGCTGCTATTGAAACTGCCACGGCCAGAATAGAGGAGATGCTCAGCAAATCC CGAGCAGGAGACACAGGAGTCAAATTGGAGGTGAATGAAAGGATCCTTGGTTGCTGTACCAGCCTCATGCAAGCTATTCAGGTGCTCATC GTGGCCTCTAAGGACCTCCAGAGAGAGATTGTGGAGAGCGGCAGGGGTACAGCATCCCCTAAAGAGTTTTATGCCAAGAACTCTCGATGG ACAGAAGGACTTATCTCAGCCTCCAAGGCTGTGGGCTGGGGAGCCACTGTCATGGTGGATGCAGCTGATCTGGTGGTACAAGGCAGAGGG AAATTTGAGGAGCTAATGGTGTGTTCTCATGAAATTGCTGCTAGCACAGCCCAGCTTGTGGCTGCATCCAAGGTGAAAGCTGATAAGGAC AGCCCCAACCTAGCCCAGCTGCAGCAGGCCTCTCGGGGAGTGAACCAGGCCACTGCCGGCGTTGTGGCCTCAACCATTTCCGGCAAATCA CAGATCGAAGAGACAGACAACATGGACTTCTCAAGCATGACGCTGACACAGATCAAACGCCAAGAGATGGATTCTCAGGTTAGGGTGCTA GAGCTAGAAAATGAATTGCAGAAGGAGCGTCAAAAACTGGGAGAGCTTCGGAAAAAGCACTACGAGCTTGCTGGTGTTGCTGAGGGCTGG GAAGAAGGAACAGAGGCATCTCCACCTACACTGCAAGAAGTGGTAACCGAAAAAGAATAGAGCCAAACCAACACCCCATATGTCAGTGTA AATCCTTGTTACCTATCTCGTGTGTGTTATTTCCCCAGCCACAGGCCAAATCCTTGGAGTCCCAGGGGCAGCCACACCACTGCCATTACC CAGTGCCGAGGACATGCATGACACTTCCAAAGACTCCCTCCATAGCGACACCCTTTCTGTTTGGACCCATGGTCATCTCTGTTCTTTTCC CGCCTCCCTAGTTAGCATCCAGGCTGGCCAGTGCTGCCCATGAGCAAGCCTAGGTACGAAGAGGGGTGGTGGGGGGCAGGGCCACTCAAC AGAGAGGACCAACATCCAGTCCTGCTGACTATTTGACCCCCACAACAATGGGTATCCTTAATAGAGGAGCTGCTTGTTGTTTGTTGACAG CTTGGAAAGGGAAGATCTTATGCCTTTTCTTTTCTGTTTTCTTCTCAGTCTTTTCAGTTTCATCATTTGCACAAACTTGTGAGCATCAGA GGGCTGATGGATTCCAAACCAGGACACTACCCTGAGATCTGCACAGTCAGAAGGACGGCAGGAGTGTCCTGGCTGTGAATGCCAAAGCCA TTCTCCCCCTCTTTGGGCAGTGCCATGGATTTCCACTGCTTCTTATGGTGGTTGGTTGGGTTTTTTGGTTTTGTTTTTTTTTTTAAGTTT CACTCACATAGCCAACTCTCCCAAAGGGCACACCCCTGGGGCTGAGTCTCCAGGGCCCCCCAACTGTGGTAGCTCCAGCGATGGTGCTGC CCAGGCCTCTCGGTGCTCCATCTCCGCCTCCACACTGACCAAGTGCTGGCCCACCCAGTCCATGCTCCAGGGTCAGGCGGAGCTGCTGAG TGACAGCTTTCCTCAAAAAGCAGAAGGAGAGTGAGTGCCTTTCCCTCCTAAAGCTGAATCCCGGCGGAAAGCCTCTGTCCGCCTTTACAA GGGAGAAGACAACAGAAAGAGGGACAAGAGGGTTCACACAGCCCAGTTCCCGTGACGAGGCTCAAAAACTTGATCACATGCTTGAATGGA GCTGGTGAGATCAACAACACTACTTCCCTGCCGGAATGAACTGTCCGTGAATGGTCTCTGTCAAGCGGGCCGTCTCCCTTGGCCCAGAGA CGGAGTGTGGGAGTGATTCCCAACTCCTTTCTGCAGACGTCTGCCTTGGCATCCTCTTGAATAGGAAGATCGTTCCACCTTCTACGCAAT TGACAAACCCGGAAGATCAGATGCAATTGCTCCCATCAGGGAAGAACCCTATACTTGGTTTGCTACCCTTAGTATTTATTACTAACCTCC CTTAAGCAGCAACAGCCTACAAAGAGATGCTTGGAGCAATCAGAACTTCAGGTGTGACTCTAGCAAGGCTCATCTTTCTGCCCGGCTACA TCAGCCTTCAAGAATCAGAAGAAAGGCCAAGGTGCTGGACTGTTACTGACTTGGATCCCAAAGCAAGGAGATCATTTGGAGCTCTTGGGT CAGAGAAAATGAGAAAGGACAGAGCCAGCGGCTCCAACTCCTTTCAGCCACATGCCCCAGGCTCTCGCTGCCCTGTGGACAGGATGAGGA CAGAGGGCACATGAACAGCTTGCCAGGGATGGGCAGCCCAACAGCACTTTTCCTCTTCTAGATGGACCCCAGCATTTAAGTGACCTTCTG ATCTTGGAAAAACAGCGTCTTCCTTCTTTATCTATAGCAACTCATTGGTGGTAGCCATCAAGCACTTCCCAGGATCTGCTCCAACAGAAT ATTGCTAGGTTTTGCTACATGACGGGTTGTGAGACTTCTGTTTGATCACTGTGAACCAACCCCCATCTCCCTAGCCCACCCCCCTCCCCA ACTCCCTCTCTGTGCATTTTCTAAGTGGGACATTCAAAAAACTCTCTCCCAGGACCTCGGATGACCATACTCAGACGTGTGACCTCCATA CTGGGCTAAGGAAGTATCAGCACTAGAAATTGGGCAGTCTTAATGTTGAATGCTGCTTTCTGCTTAGTATTTTTTTGATTCAAGGCTCAG AAGGAATGGTGCGTGGCTTCCCTGTCCCAGTTGTGGCAACTAAACCAATCGGTGTGTTCTTGATGCGGGTCAACATTTCCAAAAGTGGCT AGTCCTCACTTCTAGATCTCAGCCATTCTAACTCATATGTTCCCAATTACCAAGGGGTGGCCGGGCACAGTGGCTCACGCCTGTAATCCC AGCACTTTGAGAGGCTGAGGTGGTAGGATCACCTGAGGTCAGGAGTTCAAGACCAGCCTGTCCAACATGGTGAAACCCCCATCTCTACTA AAAATACCAAAAATTAGCCGAGCGTAGTGACGGGTGCCCGTAATCCCAGCTACTCAGGAGGCTGAGACAGGAGAATCACCTGAACCCCAG AGGCAGAGGTTGCAGTGAGCTGAGATCACGCCATTGTACTCCAGCCTGGGCAACAAGAGCAAAACTCCGTCTCAAAAAAAAAAAAAAATT ACAAATGGGGCAAACAGTCTAGTGTAATGGATCAAATTAAGATTCTCTGCCCAGCCGGGCACAGTGGCGCATGCCTGTAATCCCAGAACT TTGGGAGGCCAAGACGGGATGATTGCTTGAGCTCAGGAGTTTGAGACCAGGCTGGGCATCATAGCAAGACCTCATCTCTACTAAAATTCA AAAACAAAATTAGCCGGGCATGATGGTGCATGCCTGTAGTCTCAGCTAGTTGGGGAGCTAAGGTGGGAGAATTGCTTGAGCTTGGGAAGT CGAGGCTGCAGTCAGCCCTGATTGTGCCAGTGCACTCCGGCCTGGGTGACAGAGTGAGACCCTGTCTCAAAAAAAAAAAGATTCTGTGTC AGAGCCCAGCCCAGGAGTTTGAGGCTGCAATGAGCCATGATTTCCCACTGCACTCCAGCCTGAGTGACAGAGCGAGACTCCATCTCTTTA AAAACAAACAAAAAATTATCTGAATGATCCTGTCTCTAAAAAGAAGCCACAGAAATGTTTAAAAACTTCATCGACTTAGCCTGAGTCATA ACGGTTAAGAAAGCACTTAAACAGAAGCAGAGGCTAATTCAGTGTCACATGAGGAAGTAGCTGTCAGATGTCACATAATTACTTTCGTAA TAGCTCAGATTAGAATGGCTACCCCATTCTCTAGACAAAATCAAATTGTCCTATTGTGACTCTTCTAAAAATGAAGATGAAGAGCTATTT AATGACACACCTTGGATTAAAACGGGAATCACATCTTAAAGCTAAAAATGAACCTGCAAGCCTTCTAAATGAGTCACTGAGCATCACTAG TGACAAGTCTCGGGTGAGCGTAAATGGGTCATGACAAGATGGGACAGCAACAAAATCATGGCTTAGGATCGACAAGAAGTTAAAAAACAG CTGCATCTGTTACTTAAGTTTGTAAGACAGTGCCCTGAGACCTCTAGAGAAAAGATGTTTGTTTACATAAGAGAAAGAGGCCAGACATGG TGTCTCACACGTTTAATCCCAGCACTTTGGGAGGCAGGGGCGGGTGGATCACCTGAGGTCAGGAGTTCAAGACTAGCCTGGCCAACATGG TGAAACCCCGTCTCTACTAAAAATACAAAAATTAGCCGGGCATGGTGGCAGGCGCCTATAATCCCAGCTACTGGGGAGGCTGAGGCAGGA GAATCACTTGAACCCGGGGGACAGAGGTTGTAGTGAGCCAAGATCGCACCACTGCACTCCAGCCTGGGTCACAGAGTGAGACTCCATCTC AAAAAAAAAAAAGAGAGAGAGAGAGAAAGAAATAGAAGAGAAGAGCCATCTTGGCAGGGTTATTTTATATCTGAGCAAGGAGTTTAAATG AGACTAGTTTAGATTGTCTGCTGATGCAGCCGTCCATAGCAGTACCCCTAAAATCCCACCAGAATACGGGTCCCTCTAACCCAGTGGCTG GAAGAACCACTGTCTAGAGCAACTTTTCTTGGAACTGTCCCAGCTACCAAGTCAGACACCAAGGTTTATGCCACCAGGTAACACGGGAAT CACAGGTACATGTCGCTCCGGTCAGATTAGTTGGCTTTGGCCCCTCGACCCTGTGCAGGAGCTAGTTCTCAGCTTGCAGCTGGAAGTTCC CTCTTAGCTCCTTAGTCTAGAGGGGTCTCCTGGCTCCATTTGACCCTGGTCTTTAATAACCGGTCAGCATCTTGCTACCTTCTACCACCT TTCCAAATCTCTGGAAATCCTGCCAGGGAAAGCCTCCAGTTCCAACATTGGCTTTCCAAGCAAACTGGCTTTGCCCTCTCTCTGCCATCC TTGTCCTCCAGAGACTGCACCACCTGTAGCATAGAAAACCACCACCACGGACCTGCCAGCCATTGGCGCAGCAAACCAGCCAGCTGTTTG CTGCCAAATTCCTTCCTCTCCCAGGTCCAGACCAAATACAAGATCAGCACCACACCGTGGTGTTGTCAGGAGCCAAAGCAACAGGAAACA ATTCAATGCTGTTGGGTTCGATTCTGAGAGTAGATTTTTCCAGACATGTCTTTCAGGTGACCCTCAACTACCTCAGGTTTGAAGGCCCTA AATGAAACTGATTACCACTCATAGGGACAAACCGAGGGGGTTCGGTTACATCTTGGTGATAATGCAGTTGTCTCAAACTTATAACAGACT CTTTCACATTTCAGTTTGCAGGGATAGGGTTGGGTTTGTTTTTCTTCTGTTTTTAACCTTTCCCCTGGGTTTCCATTAGGGTAGTTCCTT GAAATGAATTTCATTTTTCACTGAGTGCCTACCTTCCCAGGGCAGGTGGCCACTGGCTTCTGTTTCCCTCCAACAATACTTTTATTATGG >67128_67128_1_POM121C-HIP1_POM121C_chr7_75066793_ENST00000257665_HIP1_chr7_75228565_ENST00000336926_length(amino acids)=1399AA_BP=0 MSPAAAAAGAGERRRPIASVRDGRGRGCGGPAGAALLGLSLVGLLLYLVPAAAALAWLAVGTTAAWWGLSREPRGSRPLSSFVQKARHRR TLFASPPAKSTANGNLLEPRTLLEGPDPAELLLMGSYLGKPGPPQPAPAPEGQDLRNRPGRRPPARPAPRSTPPSPPTHRVHHFYPSLPT PLLRPSGRPSPRDRGTLPDRFVITPRRRYPIHQTQYSCPGVLPTVCWNGYHKKAVLSPRNSRMVCSPVTVRIAPPDRRFSRSAIPEQIIS STLSSPSSNAPDPCAKETVLSALKEKKKKRTVEEEDQIFLDGQENKRRRHDSSGSGHSAFEPLVASGVPASFVPKPGSLKRGLNSQSSDD HLNKRSRSSSMSSLTGAYTSGIPSSSRNAITSSYSSTRGISQTVSINKAINTQEVAVKEKHARTCILGTHHEKGAQTFWSVVNRLPLSSN AVLCWKFCHVFHKLLRDGHPNVLKDSLRYRNELSDMSRMWGHLSEGYGQLCSIYLKLLRTKMEYHTKNPRFPGNLQMSDRQLDEAGESDV NNFFQLTVEMFDYLECELNLFQTVFNSLDMSRSVSVTAAGQCRLAPLIQVILDCSHLYDYTVKLLFKLHSCLPADTLQGHRDRFMEQFTK LKDLFYRSSNLQYFKRLIQIPQLPENPPNFLRASALSEHISPVVVIPAEASSPDSEPVLEKDDLMDMDASQQNLFDNKFDDIFGSSFSSD PFNFNSQNGVNKDEKDHLIERLYREISGLKAQLENMKTESQRVVLQLKGHVSELEADLAEQQHLRQQAADDCEFLRAELDELRRQREDTE KAQRSLSEIERKAQANEQRYSKLKEKYSELVQNHADLLRKNAEVTKQVSMARQAQVDLEREKKELEDSLERISDQGQRKTQEQLEVLESL KQELATSQRELQVLQGSLETSAQSEANWAAEFAELEKERDSLVSGAAHREEELSALRKELQDTQLKLASTEESMCQLAKDQRKMLLVGSR KAAEQVIQDALNQLEEPPLISCAGSADHLLSTVTSISSCIEQLEKSWSQYLACPEDISGLLHSITLLAHLTSDAIAHGATTCLRAPPEPA DSLTEACKQYGRETLAYLASLEEEGSLENADSTAMRNCLSKIKAIGEELLPRGLDIKQEELGDLVDKEMAATSAAIETATARIEEMLSKS RAGDTGVKLEVNERILGCCTSLMQAIQVLIVASKDLQREIVESGRGTASPKEFYAKNSRWTEGLISASKAVGWGATVMVDAADLVVQGRG KFEELMVCSHEIAASTAQLVAASKVKADKDSPNLAQLQQASRGVNQATAGVVASTISGKSQIEETDNMDFSSMTLTQIKRQEMDSQVRVL -------------------------------------------------------------- >67128_67128_2_POM121C-HIP1_POM121C_chr7_75066793_ENST00000257665_HIP1_chr7_75228565_ENST00000434438_length(transcript)=8131nt_BP=1206nt ATGTCTCCGGCGGCTGCGGCGGCTGGAGCAGGCGAGCGGCGGCGGCCGATAGCGAGTGTCAGGGACGGCCGGGGCCGGGGCTGCGGCGGG CCGGCCGGGGCGGCGCTTCTCGGCCTGTCGCTGGTCGGCCTCCTACTGTACCTCGTGCCTGCTGCGGCTGCGCTGGCCTGGCTGGCCGTG GGGACTACCGCGGCCTGGTGGGGACTGAGCCGCGAGCCCCGAGGTTCGCGCCCCTTGTCCTCCTTCGTTCAGAAGGCGCGACATCGGCGA ACACTGTTCGCTTCGCCTCCGGCCAAGTCGACAGCCAACGGAAACCTCCTAGAGCCGCGGACCCTGCTCGAAGGACCTGACCCTGCCGAA CTGCTCCTCATGGGCAGTTACCTGGGCAAGCCCGGGCCGCCGCAGCCCGCCCCCGCTCCGGAGGGCCAGGACCTGCGGAATAGGCCTGGC CGCCGCCCACCCGCCCGCCCGGCGCCGCGCTCCACACCGCCCTCCCCGCCGACCCATCGCGTTCACCACTTTTACCCCTCTCTCCCCACT CCTCTTCTCCGACCCTCCGGGAGGCCTTCCCCACGGGATCGTGGGACTTTACCAGATCGGTTTGTAATAACACCTCGAAGACGCTATCCG ATCCATCAGACCCAGTATTCCTGTCCGGGGGTACTTCCCACAGTGTGCTGGAATGGTTATCACAAGAAGGCTGTGCTGTCCCCTCGCAAC TCCAGGATGGTGTGTAGCCCAGTGACTGTGAGGATCGCCCCTCCTGACAGAAGATTTTCACGTTCTGCGATACCAGAGCAGATAATCAGC TCAACACTGTCGTCACCATCAAGTAATGCCCCAGACCCATGTGCAAAGGAGACTGTACTGAGTGCCCTCAAAGAGAAGAAGAAGAAAAGG ACAGTGGAGGAAGAAGACCAAATATTCCTTGATGGCCAGGAAAATAAAAGAAGGCGCCATGATAGCAGTGGCAGTGGACATTCAGCATTT GAGCCCCTGGTGGCCAGTGGAGTCCCCGCTTCTTTTGTGCCTAAGCCTGGGTCTCTGAAGAGAGGCCTCAATTCTCAGAGCTCAGATGAC CACTTGAATAAGAGATCCCGAAGCTCTTCCATGAGCTCCTTGACAGGCGCTTACACAAGTGGCATCCCTAGCTCCAGCCGCAATGCCATT ACCAGTTCCTACAGCTCCACTCGAGGCATCTCACAGACTGTCAGCATCAATAAGGCCATTAATACGCAGGAAGTGGCTGTAAAGGAAAAA CACGCCAGAACGTGCATACTGGGCACCCACCATGAGAAAGGGGCACAGACCTTCTGGTCTGTTGTCAACCGCCTGCCTCTGTCTAGCAAC GCAGTGCTCTGCTGGAAGTTCTGCCATGTGTTCCACAAACTCCTCCGAGATGGACACCCGAACGTCCTGAAGGACTCTCTGAGATACAGA AATGAATTGAGTGACATGAGCAGGATGTGGGGCCACCTGAGCGAGGGGTATGGCCAGCTGTGCAGCATCTACCTGAAACTGCTAAGAACC AAGATGGAGTACCACACCAAAAATCCCAGGTTCCCAGGCAACCTGCAGATGAGTGACCGCCAGCTGGACGAGGCTGGAGAAAGTGACGTG AACAACTTTTTCCAGTTAACAGTGGAGATGTTTGACTACCTGGAGTGTGAACTCAACCTCTTCCAAACAGTATTCAACTCCCTGGACATG TCCCGCTCTGTGTCCGTGACGGCAGCAGGGCAGTGCCGCCTCGCCCCGCTGATCCAGGTCATCTTGGACTGCAGCCACCTTTATGACTAC ACTGTCAAGCTTCTCTTCAAACTCCACTCCTGCCTCCCAGCTGACACCCTGCAAGGCCACCGGGACCGCTTCATGGAGCAGTTTACAAAG TTGAAAGATCTGTTCTACCGCTCCAGCAACCTGCAGTACTTCAAGCGGCTCATTCAGATCCCCCAGCTGCCTGAGAACCCACCCAACTTC CTGCGAGCCTCAGCCCTGTCAGAACATATCAGCCCTGTGGTGGTGATCCCTGCAGAGGCCTCATCCCCCGACAGCGAGCCAGTCCTAGAG AAGGATGACCTCATGGACATGGATGCCTCTCAGCAGAATTTATTTGACAACAAGTTTGATGACATCTTTGGCAGTTCATTCAGCAGTGAT CCCTTCAATTTCAACAGTCAAAATGGTGTGAACAAGGATGAGAAGGACCACTTAATTGAGCGACTATACAGAGAGATCAGTGGATTGAAG GCACAGCTAGAAAACATGAAGACTGAGAGCCAGCGGGTTGTGCTGCAGCTGAAGGGCCACGTCAGCGAGCTGGAAGCAGATCTGGCCGAG CAGCAGCACCTGCGGCAGCAGGCGGCCGACGACTGTGAATTCCTGCGGGCAGAACTGGACGAGCTCAGGAGGCAGCGGGAGGACACCGAG AAGGCTCAGCGGAGCCTGTCTGAGATAGAAAGGAAAGCTCAAGCCAATGAACAGCGATATAGCAAGCTAAAGGAGAAGTACAGCGAGCTG GTTCAGAACCACGCTGACCTGCTGCGGAAGAATGCAGAGGTGACCAAACAGGTGTCCATGGCCAGACAAGCCCAGGTAGATTTGGAACGA GAGAAAAAAGAGCTGGAGGATTCGTTGGAGCGCATCAGTGACCAGGGCCAGCGGAAGACTCAAGAACAGCTGGAAGTTCTAGAGAGCTTG AAGCAGGAACTTGCCACAAGCCAACGGGAGCTTCAGGTTCTGCAAGGCAGCCTGGAAACTTCTGCCCAGTCAGAAGCAAACTGGGCAGCC GAGTTCGCCGAGCTAGAGAAGGAGCGGGACAGCCTGGTGAGTGGCGCAGCTCATAGGGAGGAGGAATTATCTGCTCTTCGGAAAGAACTG CAGGACACTCAGCTCAAACTGGCCAGCACAGAGGAATCTATGTGCCAGCTTGCCAAAGACCAACGAAAAATGCTTCTGGTGGGGTCCAGG AAGGCTGCGGAGCAGGTGATACAAGACGCCCTGAACCAGCTTGAAGAACCTCCTCTCATCAGCTGCGCTGGGTCTGCAGATCACCTCCTC TCCACGGTCACATCCATTTCCAGCTGCATCGAGCAACTGGAGAAAAGCTGGAGCCAGTATCTGGCCTGCCCAGAAGACATCAGTGGACTT CTCCATTCCATAACCCTGCTGGCCCACTTGACCAGCGACGCCATTGCTCATGGTGCCACCACCTGCCTCAGAGCCCCACCTGAGCCTGCC GACTCACTGACCGAGGCCTGTAAGCAGTATGGCAGGGAAACCCTCGCCTACCTGGCCTCCCTGGAGGAAGAGGGAAGCCTTGAGAATGCC GACAGCACAGCCATGAGGAACTGCCTGAGCAAGATCAAGGCCATCGGCGAGGAGCTCCTGCCCAGGGGACTGGACATCAAGCAGGAGGAG CTGGGGGACCTGGTGGACAAGGAGATGGCGGCCACTTCAGCTGCTATTGAAACTGCCACGGCCAGAATAGAGGGTACAGCATCCCCTAAA GAGTTTTATGCCAAGAACTCTCGATGGACAGAAGGACTTATCTCAGCCTCCAAGGCTGTGGGCTGGGGAGCCACTGTCATGGTGGATGCA GCTGATCTGGTGGTACAAGGCAGAGGGAAATTTGAGGAGCTAATGGTGTGTTCTCATGAAATTGCTGCTAGCACAGCCCAGCTTGTGGCT GCATCCAAGGTGAAAGCTGATAAGGACAGCCCCAACCTAGCCCAGCTGCAGCAGGCCTCTCGGGGAGTGAACCAGGCCACTGCCGGCGTT GTGGCCTCAACCATTTCCGGCAAATCACAGATCGAAGAGACAGACAACATGGACTTCTCAAGCATGACGCTGACACAGATCAAACGCCAA GAGATGGATTCTCAGGTTAGGGTGCTAGAGCTAGAAAATGAATTGCAGAAGGAGCGTCAAAAACTGGGAGAGCTTCGGAAAAAGCACTAC GAGCTTGCTGGTGTTGCTGAGGGCTGGGAAGAAGGAACAGAGGCATCTCCACCTACACTGCAAGAAGTGGTAACCGAAAAAGAATAGAGC CAAACCAACACCCCATATGTCAGTGTAAATCCTTGTTACCTATCTCGTGTGTGTTATTTCCCCAGCCACAGGCCAAATCCTTGGAGTCCC AGGGGCAGCCACACCACTGCCATTACCCAGTGCCGAGGACATGCATGACACTTCCAAAGACTCCCTCCATAGCGACACCCTTTCTGTTTG GACCCATGGTCATCTCTGTTCTTTTCCCGCCTCCCTAGTTAGCATCCAGGCTGGCCAGTGCTGCCCATGAGCAAGCCTAGGTACGAAGAG GGGTGGTGGGGGGCAGGGCCACTCAACAGAGAGGACCAACATCCAGTCCTGCTGACTATTTGACCCCCACAACAATGGGTATCCTTAATA GAGGAGCTGCTTGTTGTTTGTTGACAGCTTGGAAAGGGAAGATCTTATGCCTTTTCTTTTCTGTTTTCTTCTCAGTCTTTTCAGTTTCAT CATTTGCACAAACTTGTGAGCATCAGAGGGCTGATGGATTCCAAACCAGGACACTACCCTGAGATCTGCACAGTCAGAAGGACGGCAGGA GTGTCCTGGCTGTGAATGCCAAAGCCATTCTCCCCCTCTTTGGGCAGTGCCATGGATTTCCACTGCTTCTTATGGTGGTTGGTTGGGTTT TTTGGTTTTGTTTTTTTTTTTAAGTTTCACTCACATAGCCAACTCTCCCAAAGGGCACACCCCTGGGGCTGAGTCTCCAGGGCCCCCCAA CTGTGGTAGCTCCAGCGATGGTGCTGCCCAGGCCTCTCGGTGCTCCATCTCCGCCTCCACACTGACCAAGTGCTGGCCCACCCAGTCCAT GCTCCAGGGTCAGGCGGAGCTGCTGAGTGACAGCTTTCCTCAAAAAGCAGAAGGAGAGTGAGTGCCTTTCCCTCCTAAAGCTGAATCCCG GCGGAAAGCCTCTGTCCGCCTTTACAAGGGAGAAGACAACAGAAAGAGGGACAAGAGGGTTCACACAGCCCAGTTCCCGTGACGAGGCTC AAAAACTTGATCACATGCTTGAATGGAGCTGGTGAGATCAACAACACTACTTCCCTGCCGGAATGAACTGTCCGTGAATGGTCTCTGTCA AGCGGGCCGTCTCCCTTGGCCCAGAGACGGAGTGTGGGAGTGATTCCCAACTCCTTTCTGCAGACGTCTGCCTTGGCATCCTCTTGAATA GGAAGATCGTTCCACCTTCTACGCAATTGACAAACCCGGAAGATCAGATGCAATTGCTCCCATCAGGGAAGAACCCTATACTTGGTTTGC TACCCTTAGTATTTATTACTAACCTCCCTTAAGCAGCAACAGCCTACAAAGAGATGCTTGGAGCAATCAGAACTTCAGGTGTGACTCTAG CAAGGCTCATCTTTCTGCCCGGCTACATCAGCCTTCAAGAATCAGAAGAAAGGCCAAGGTGCTGGACTGTTACTGACTTGGATCCCAAAG CAAGGAGATCATTTGGAGCTCTTGGGTCAGAGAAAATGAGAAAGGACAGAGCCAGCGGCTCCAACTCCTTTCAGCCACATGCCCCAGGCT CTCGCTGCCCTGTGGACAGGATGAGGACAGAGGGCACATGAACAGCTTGCCAGGGATGGGCAGCCCAACAGCACTTTTCCTCTTCTAGAT GGACCCCAGCATTTAAGTGACCTTCTGATCTTGGAAAAACAGCGTCTTCCTTCTTTATCTATAGCAACTCATTGGTGGTAGCCATCAAGC ACTTCCCAGGATCTGCTCCAACAGAATATTGCTAGGTTTTGCTACATGACGGGTTGTGAGACTTCTGTTTGATCACTGTGAACCAACCCC CATCTCCCTAGCCCACCCCCCTCCCCAACTCCCTCTCTGTGCATTTTCTAAGTGGGACATTCAAAAAACTCTCTCCCAGGACCTCGGATG ACCATACTCAGACGTGTGACCTCCATACTGGGCTAAGGAAGTATCAGCACTAGAAATTGGGCAGTCTTAATGTTGAATGCTGCTTTCTGC TTAGTATTTTTTTGATTCAAGGCTCAGAAGGAATGGTGCGTGGCTTCCCTGTCCCAGTTGTGGCAACTAAACCAATCGGTGTGTTCTTGA TGCGGGTCAACATTTCCAAAAGTGGCTAGTCCTCACTTCTAGATCTCAGCCATTCTAACTCATATGTTCCCAATTACCAAGGGGTGGCCG GGCACAGTGGCTCACGCCTGTAATCCCAGCACTTTGAGAGGCTGAGGTGGTAGGATCACCTGAGGTCAGGAGTTCAAGACCAGCCTGTCC AACATGGTGAAACCCCCATCTCTACTAAAAATACCAAAAATTAGCCGAGCGTAGTGACGGGTGCCCGTAATCCCAGCTACTCAGGAGGCT GAGACAGGAGAATCACCTGAACCCCAGAGGCAGAGGTTGCAGTGAGCTGAGATCACGCCATTGTACTCCAGCCTGGGCAACAAGAGCAAA ACTCCGTCTCAAAAAAAAAAAAAAATTACAAATGGGGCAAACAGTCTAGTGTAATGGATCAAATTAAGATTCTCTGCCCAGCCGGGCACA GTGGCGCATGCCTGTAATCCCAGAACTTTGGGAGGCCAAGACGGGATGATTGCTTGAGCTCAGGAGTTTGAGACCAGGCTGGGCATCATA GCAAGACCTCATCTCTACTAAAATTCAAAAACAAAATTAGCCGGGCATGATGGTGCATGCCTGTAGTCTCAGCTAGTTGGGGAGCTAAGG TGGGAGAATTGCTTGAGCTTGGGAAGTCGAGGCTGCAGTCAGCCCTGATTGTGCCAGTGCACTCCGGCCTGGGTGACAGAGTGAGACCCT GTCTCAAAAAAAAAAAGATTCTGTGTCAGAGCCCAGCCCAGGAGTTTGAGGCTGCAATGAGCCATGATTTCCCACTGCACTCCAGCCTGA GTGACAGAGCGAGACTCCATCTCTTTAAAAACAAACAAAAAATTATCTGAATGATCCTGTCTCTAAAAAGAAGCCACAGAAATGTTTAAA AACTTCATCGACTTAGCCTGAGTCATAACGGTTAAGAAAGCACTTAAACAGAAGCAGAGGCTAATTCAGTGTCACATGAGGAAGTAGCTG TCAGATGTCACATAATTACTTTCGTAATAGCTCAGATTAGAATGGCTACCCCATTCTCTAGACAAAATCAAATTGTCCTATTGTGACTCT TCTAAAAATGAAGATGAAGAGCTATTTAATGACACACCTTGGATTAAAACGGGAATCACATCTTAAAGCTAAAAATGAACCTGCAAGCCT TCTAAATGAGTCACTGAGCATCACTAGTGACAAGTCTCGGGTGAGCGTAAATGGGTCATGACAAGATGGGACAGCAACAAAATCATGGCT TAGGATCGACAAGAAGTTAAAAAACAGCTGCATCTGTTACTTAAGTTTGTAAGACAGTGCCCTGAGACCTCTAGAGAAAAGATGTTTGTT TACATAAGAGAAAGAGGCCAGACATGGTGTCTCACACGTTTAATCCCAGCACTTTGGGAGGCAGGGGCGGGTGGATCACCTGAGGTCAGG AGTTCAAGACTAGCCTGGCCAACATGGTGAAACCCCGTCTCTACTAAAAATACAAAAATTAGCCGGGCATGGTGGCAGGCGCCTATAATC CCAGCTACTGGGGAGGCTGAGGCAGGAGAATCACTTGAACCCGGGGGACAGAGGTTGTAGTGAGCCAAGATCGCACCACTGCACTCCAGC CTGGGTCACAGAGTGAGACTCCATCTCAAAAAAAAAAAAGAGAGAGAGAGAGAAAGAAATAGAAGAGAAGAGCCATCTTGGCAGGGTTAT TTTATATCTGAGCAAGGAGTTTAAATGAGACTAGTTTAGATTGTCTGCTGATGCAGCCGTCCATAGCAGTACCCCTAAAATCCCACCAGA ATACGGGTCCCTCTAACCCAGTGGCTGGAAGAACCACTGTCTAGAGCAACTTTTCTTGGAACTGTCCCAGCTACCAAGTCAGACACCAAG GTTTATGCCACCAGGTAACACGGGAATCACAGGTACATGTCGCTCCGGTCAGATTAGTTGGCTTTGGCCCCTCGACCCTGTGCAGGAGCT >67128_67128_2_POM121C-HIP1_POM121C_chr7_75066793_ENST00000257665_HIP1_chr7_75228565_ENST00000434438_length(amino acids)=1348AA_BP=0 MSPAAAAAGAGERRRPIASVRDGRGRGCGGPAGAALLGLSLVGLLLYLVPAAAALAWLAVGTTAAWWGLSREPRGSRPLSSFVQKARHRR TLFASPPAKSTANGNLLEPRTLLEGPDPAELLLMGSYLGKPGPPQPAPAPEGQDLRNRPGRRPPARPAPRSTPPSPPTHRVHHFYPSLPT PLLRPSGRPSPRDRGTLPDRFVITPRRRYPIHQTQYSCPGVLPTVCWNGYHKKAVLSPRNSRMVCSPVTVRIAPPDRRFSRSAIPEQIIS STLSSPSSNAPDPCAKETVLSALKEKKKKRTVEEEDQIFLDGQENKRRRHDSSGSGHSAFEPLVASGVPASFVPKPGSLKRGLNSQSSDD HLNKRSRSSSMSSLTGAYTSGIPSSSRNAITSSYSSTRGISQTVSINKAINTQEVAVKEKHARTCILGTHHEKGAQTFWSVVNRLPLSSN AVLCWKFCHVFHKLLRDGHPNVLKDSLRYRNELSDMSRMWGHLSEGYGQLCSIYLKLLRTKMEYHTKNPRFPGNLQMSDRQLDEAGESDV NNFFQLTVEMFDYLECELNLFQTVFNSLDMSRSVSVTAAGQCRLAPLIQVILDCSHLYDYTVKLLFKLHSCLPADTLQGHRDRFMEQFTK LKDLFYRSSNLQYFKRLIQIPQLPENPPNFLRASALSEHISPVVVIPAEASSPDSEPVLEKDDLMDMDASQQNLFDNKFDDIFGSSFSSD PFNFNSQNGVNKDEKDHLIERLYREISGLKAQLENMKTESQRVVLQLKGHVSELEADLAEQQHLRQQAADDCEFLRAELDELRRQREDTE KAQRSLSEIERKAQANEQRYSKLKEKYSELVQNHADLLRKNAEVTKQVSMARQAQVDLEREKKELEDSLERISDQGQRKTQEQLEVLESL KQELATSQRELQVLQGSLETSAQSEANWAAEFAELEKERDSLVSGAAHREEELSALRKELQDTQLKLASTEESMCQLAKDQRKMLLVGSR KAAEQVIQDALNQLEEPPLISCAGSADHLLSTVTSISSCIEQLEKSWSQYLACPEDISGLLHSITLLAHLTSDAIAHGATTCLRAPPEPA DSLTEACKQYGRETLAYLASLEEEGSLENADSTAMRNCLSKIKAIGEELLPRGLDIKQEELGDLVDKEMAATSAAIETATARIEGTASPK EFYAKNSRWTEGLISASKAVGWGATVMVDAADLVVQGRGKFEELMVCSHEIAASTAQLVAASKVKADKDSPNLAQLQQASRGVNQATAGV -------------------------------------------------------------- |
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Fusion Gene PPI Analysis for POM121C-HIP1 |
| Go to ChiPPI (Chimeric Protein-Protein interactions) to see the chimeric PPI interaction in |
| Protein-protein interactors with each fusion partner protein in wild-type (BIOGRID-3.4.160) |
| Hgene | Hgene's interactors | Tgene | Tgene's interactors |
| - Retained PPIs in in-frame fusion. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Still interaction with |
| - Lost PPIs in in-frame fusion. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Interaction lost with |
| - Retained PPIs, but lost function due to frame-shift fusion. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Interaction lost with |
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Related Drugs for POM121C-HIP1 |
| Drugs targeting genes involved in this fusion gene. (DrugBank Version 5.1.8 2021-05-08) |
| Partner | Gene | UniProtAcc | DrugBank ID | Drug name | Drug activity | Drug type | Drug status |
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Related Diseases for POM121C-HIP1 |
| Diseases associated with fusion partners. (DisGeNet 4.0) |
| Partner | Gene | Disease ID | Disease name | # pubmeds | Source |
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