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Center for Computational Systems Medicine
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Fusion Gene Summary

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Fusion Gene ORF analysis

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Fusion Genomic Features

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Fusion Protein Features

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Fusion Gene Sequence

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Fusion Gene PPI analysis

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Related Drugs

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Related Diseases

Fusion gene:PPFIA1-ARHGAP32 (FusionGDB2 ID:67383)

Fusion Gene Summary for PPFIA1-ARHGAP32

check button Fusion gene summary
Fusion gene informationFusion gene name: PPFIA1-ARHGAP32
Fusion gene ID: 67383
HgeneTgene
Gene symbol

PPFIA1

ARHGAP32

Gene ID

8500

9743

Gene namePTPRF interacting protein alpha 1Rho GTPase activating protein 32
SynonymsLIP.1|LIP1|LIPRINGC-GAP|GRIT|PX-RICS|RICS|p200RhoGAP|p250GAP
Cytomap

11q13.3

11q24.3

Type of geneprotein-codingprotein-coding
Descriptionliprin-alpha-1LAR-interacting protein 1LIP-1Liprin-alpha1protein tyrosine phosphatase receptor type f polypeptide-interacting protein alpha-1protein tyrosine phosphatase, receptor type, f polypeptide (PTPRF), interacting protein (liprin), alpha 1rho GTPase-activating protein 32GAB-associated CDC42GAB-associated Cdc42/Rac GTPase-activating proteinGTPase regulator interacting with TrkAGTPase-activating protein for Cdc42 and Rac1RhoGAP involved in the -catenin-N-cadherin and NMDA receptor signa
Modification date2020032720200327
UniProtAcc.

A7KAX9

Ensembl transtripts involved in fusion geneENST00000253925, ENST00000389547, 
ENST00000530548, 		ENST00000392657, 
ENST00000527272, ENST00000310343, 
ENST00000524655, 
Fusion gene scores* DoF score44 X 20 X 15=132007 X 6 X 5=210
# samples 607
** MAII scorelog2(60/13200*10)=-4.4594316186373
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0		log2(7/210*10)=-1.58496250072116
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0
Context

PubMed: PPFIA1 [Title/Abstract] AND ARHGAP32 [Title/Abstract] AND fusion [Title/Abstract]

Most frequent breakpointPPFIA1(70118542)-ARHGAP32(128963602), # samples:4
Anticipated loss of major functional domain due to fusion event.
* DoF score (Degree of Frequency) = # partners X # break points X # cancer types
** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10)

check button Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez
PartnerGeneGO IDGO termPubMed ID

check buttonFusion gene breakpoints across PPFIA1 (5'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.
all structure

check buttonFusion gene breakpoints across ARHGAP32 (3'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.
all structure

check button Fusion gene information from two resources (ChiTars 5.0 and ChimerDB 4.0)
* All genome coordinats were lifted-over on hg19.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
SourceDiseaseSampleHgeneHchrHbpHstrandTgeneTchrTbpTstrand
ChimerDB4BRCATCGA-E2-A14S-01APPFIA1chr11

70118542

-ARHGAP32chr11

128963602

-
ChimerDB4BRCATCGA-E2-A14S-01APPFIA1chr11

70118542

+ARHGAP32chr11

128963602

-
ChimerDB4BRCATCGA-E2-A14SPPFIA1chr11

70118542

+ARHGAP32chr11

128963602

-


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Fusion Gene ORF analysis for PPFIA1-ARHGAP32

check button Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
ORFHenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrand
5CDS-intronENST00000253925ENST00000392657PPFIA1chr11

70118542

+ARHGAP32chr11

128963602

-
5CDS-intronENST00000253925ENST00000527272PPFIA1chr11

70118542

+ARHGAP32chr11

128963602

-
5CDS-intronENST00000389547ENST00000392657PPFIA1chr11

70118542

+ARHGAP32chr11

128963602

-
5CDS-intronENST00000389547ENST00000527272PPFIA1chr11

70118542

+ARHGAP32chr11

128963602

-
In-frameENST00000253925ENST00000310343PPFIA1chr11

70118542

+ARHGAP32chr11

128963602

-
In-frameENST00000253925ENST00000524655PPFIA1chr11

70118542

+ARHGAP32chr11

128963602

-
In-frameENST00000389547ENST00000310343PPFIA1chr11

70118542

+ARHGAP32chr11

128963602

-
In-frameENST00000389547ENST00000524655PPFIA1chr11

70118542

+ARHGAP32chr11

128963602

-
intron-3CDSENST00000530548ENST00000310343PPFIA1chr11

70118542

+ARHGAP32chr11

128963602

-
intron-3CDSENST00000530548ENST00000524655PPFIA1chr11

70118542

+ARHGAP32chr11

128963602

-
intron-intronENST00000530548ENST00000392657PPFIA1chr11

70118542

+ARHGAP32chr11

128963602

-
intron-intronENST00000530548ENST00000527272PPFIA1chr11

70118542

+ARHGAP32chr11

128963602

-

check buttonORFfinder result based on the fusion transcript sequence of in-frame fusion genes.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandSeq length
(transcript)		BP loci
(transcript)		Predicted start
(transcript)		Predicted stop
(transcript)		Seq length
(amino acids)
ENST00000253925PPFIA1chr1170118542+ENST00000310343ARHGAP32chr11128963602-101884796563402091
ENST00000253925PPFIA1chr1170118542+ENST00000524655ARHGAP32chr11128963602-84694796531391024
ENST00000389547PPFIA1chr1170118542+ENST00000310343ARHGAP32chr11128963602-101714624863232091
ENST00000389547PPFIA1chr1170118542+ENST00000524655ARHGAP32chr11128963602-84524624831221024

check buttonDeepORF prediction of the coding potential based on the fusion transcript sequence of in-frame fusion genes. DeepORF is a coding potential classifier based on convolutional neural network by comparing the real Ribo-seq data. If the no-coding score < 0.5 and coding score > 0.5, then the in-frame fusion transcript is predicted as being likely translated.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandNo-coding scoreCoding score
ENST00000253925ENST00000310343PPFIA1chr1170118542+ARHGAP32chr11128963602-0.0003781260.99962187
ENST00000253925ENST00000524655PPFIA1chr1170118542+ARHGAP32chr11128963602-0.0007132750.9992867
ENST00000389547ENST00000310343PPFIA1chr1170118542+ARHGAP32chr11128963602-0.0003695240.99963045
ENST00000389547ENST00000524655PPFIA1chr1170118542+ARHGAP32chr11128963602-0.0007097550.9992902

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Fusion Genomic Features for PPFIA1-ARHGAP32


check buttonFusionAI prediction of the potential fusion gene breakpoint based on the pre-mature RNA sequence context (+/- 5kb of individual partner genes, total 20kb length sequence). FusionAI is a fusion gene breakpoint classifier based on convolutional neural network by comparing the fusion positive and negative sequence context of ~ 20K fusion gene data. From here, we can have the relative potentency of the 20K genomic sequence how individual sequnce will be likely used as the gene fusion breakpoints.
HgeneHchrHbpHstrandTgeneTchrTbpTstrand1-pp (fusion gene breakpoint)

check buttonDistribution of 44 human genomic features loci across 20kb length fusion breakpoint regions. We integrated a total of 44 different types of human genomic feature loci information across five big categories including virus integration sites, repeats, structural variants, chromatin states, and gene expression regulation. More details are in help page.
genomic feature

check buttonDistribution of 44 human genomic features loci across 20kb length fusion breakpoint regions that are ovelapped with the top 1% feature importance score regions. More details are in help page.

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Fusion Protein Features for PPFIA1-ARHGAP32


check button Four levels of functional features of fusion genes
Go to FGviewer search page for the most frequent breakpoint (https://ccsmweb.uth.edu/FGviewer/chr11:70118542/chr11:128963602)
- FGviewer provides the online visualization of the retention search of the protein functional features across DNA, RNA, protein, and pathological levels.
- How to search
1. Put your fusion gene symbol.
2. Press the tab key until there will be shown the breakpoint information filled.
4. Go down and press 'Search' tab twice.
4. Go down to have the hyperlink of the search result.
5. Click the hyperlink.
6. See the FGviewer result for your fusion gene.
FGviewer

check buttonMain function of each fusion partner protein. (from UniProt)
HgeneTgene
.ARHGAP32

A7KAX9

FUNCTION: Transcriptional activator which is required for calcium-dependent dendritic growth and branching in cortical neurons. Recruits CREB-binding protein (CREBBP) to nuclear bodies. Component of the CREST-BRG1 complex, a multiprotein complex that regulates promoter activation by orchestrating a calcium-dependent release of a repressor complex and a recruitment of an activator complex. In resting neurons, transcription of the c-FOS promoter is inhibited by BRG1-dependent recruitment of a phospho-RB1-HDAC1 repressor complex. Upon calcium influx, RB1 is dephosphorylated by calcineurin, which leads to release of the repressor complex. At the same time, there is increased recruitment of CREBBP to the promoter by a CREST-dependent mechanism, which leads to transcriptional activation. The CREST-BRG1 complex also binds to the NR2B promoter, and activity-dependent induction of NR2B expression involves a release of HDAC1 and recruitment of CREBBP (By similarity). {ECO:0000250}.FUNCTION: GTPase-activating protein (GAP) promoting GTP hydrolysis on RHOA, CDC42 and RAC1 small GTPases. May be involved in the differentiation of neuronal cells during the formation of neurite extensions. Involved in NMDA receptor activity-dependent actin reorganization in dendritic spines. May mediate cross-talks between Ras- and Rho-regulated signaling pathways in cell growth regulation. Isoform 2 has higher GAP activity (By similarity). {ECO:0000250, ECO:0000269|PubMed:12446789, ECO:0000269|PubMed:12454018, ECO:0000269|PubMed:12531901, ECO:0000269|PubMed:12788081, ECO:0000269|PubMed:12819203, ECO:0000269|PubMed:12857875, ECO:0000269|PubMed:17663722}.

check buttonRetention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at

download page


* Minus value of BPloci means that the break pointn is located before the CDS.
- In-frame and retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
HgenePPFIA1chr11:70118542chr11:128963602ENST00000253925+22817_25881597.3333333333333Compositional biasNote=Poly-Gly
HgenePPFIA1chr11:70118542chr11:128963602ENST00000389547+22617_25881186.0Compositional biasNote=Poly-Gly
TgeneARHGAP32chr11:70118542chr11:128963602ENST000003103433221031_10361342088.0Compositional biasNote=Poly-Pro
TgeneARHGAP32chr11:70118542chr11:128963602ENST000003103433221305_13101342088.0Compositional biasNote=Poly-Pro
TgeneARHGAP32chr11:70118542chr11:128963602ENST000003926570131031_103601739.0Compositional biasNote=Poly-Pro
TgeneARHGAP32chr11:70118542chr11:128963602ENST000003926570131305_131001739.0Compositional biasNote=Poly-Pro
TgeneARHGAP32chr11:70118542chr11:128963602ENST000005272720121031_103601739.0Compositional biasNote=Poly-Pro
TgeneARHGAP32chr11:70118542chr11:128963602ENST000005272720121305_131001739.0Compositional biasNote=Poly-Pro
TgeneARHGAP32chr11:70118542chr11:128963602ENST00000310343322131_2451342088.0DomainNote=PX%3B atypical
TgeneARHGAP32chr11:70118542chr11:128963602ENST00000310343322259_3211342088.0DomainSH3
TgeneARHGAP32chr11:70118542chr11:128963602ENST00000310343322372_5671342088.0DomainRho-GAP
TgeneARHGAP32chr11:70118542chr11:128963602ENST00000392657013131_24501739.0DomainNote=PX%3B atypical
TgeneARHGAP32chr11:70118542chr11:128963602ENST00000392657013259_32101739.0DomainSH3
TgeneARHGAP32chr11:70118542chr11:128963602ENST00000392657013372_56701739.0DomainRho-GAP
TgeneARHGAP32chr11:70118542chr11:128963602ENST00000527272012131_24501739.0DomainNote=PX%3B atypical
TgeneARHGAP32chr11:70118542chr11:128963602ENST00000527272012259_32101739.0DomainSH3
TgeneARHGAP32chr11:70118542chr11:128963602ENST00000527272012372_56701739.0DomainRho-GAP

- In-frame and not-retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
HgenePPFIA1chr11:70118542chr11:128963602ENST00000253925+2281021_1050881597.3333333333333Coiled coilOntology_term=ECO:0000255
HgenePPFIA1chr11:70118542chr11:128963602ENST00000253925+228176_214881597.3333333333333Coiled coilOntology_term=ECO:0000255
HgenePPFIA1chr11:70118542chr11:128963602ENST00000253925+228249_521881597.3333333333333Coiled coilOntology_term=ECO:0000255
HgenePPFIA1chr11:70118542chr11:128963602ENST00000253925+22834_141881597.3333333333333Coiled coilOntology_term=ECO:0000255
HgenePPFIA1chr11:70118542chr11:128963602ENST00000253925+228623_669881597.3333333333333Coiled coilOntology_term=ECO:0000255
HgenePPFIA1chr11:70118542chr11:128963602ENST00000253925+228847_871881597.3333333333333Coiled coilOntology_term=ECO:0000255
HgenePPFIA1chr11:70118542chr11:128963602ENST00000389547+2261021_1050881186.0Coiled coilOntology_term=ECO:0000255
HgenePPFIA1chr11:70118542chr11:128963602ENST00000389547+226176_214881186.0Coiled coilOntology_term=ECO:0000255
HgenePPFIA1chr11:70118542chr11:128963602ENST00000389547+226249_521881186.0Coiled coilOntology_term=ECO:0000255
HgenePPFIA1chr11:70118542chr11:128963602ENST00000389547+22634_141881186.0Coiled coilOntology_term=ECO:0000255
HgenePPFIA1chr11:70118542chr11:128963602ENST00000389547+226623_669881186.0Coiled coilOntology_term=ECO:0000255
HgenePPFIA1chr11:70118542chr11:128963602ENST00000389547+226847_871881186.0Coiled coilOntology_term=ECO:0000255
HgenePPFIA1chr11:70118542chr11:128963602ENST00000253925+2281051_1120881597.3333333333333DomainSAM 3
HgenePPFIA1chr11:70118542chr11:128963602ENST00000253925+228878_944881597.3333333333333DomainSAM 1
HgenePPFIA1chr11:70118542chr11:128963602ENST00000253925+228963_1027881597.3333333333333DomainSAM 2
HgenePPFIA1chr11:70118542chr11:128963602ENST00000389547+2261051_1120881186.0DomainSAM 3
HgenePPFIA1chr11:70118542chr11:128963602ENST00000389547+226878_944881186.0DomainSAM 1
HgenePPFIA1chr11:70118542chr11:128963602ENST00000389547+226963_1027881186.0DomainSAM 2


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Fusion Gene Sequence for PPFIA1-ARHGAP32


check button For in-frame fusion transcripts, we provide the fusion transcript sequences and fusion amino acid sequences. To have fusion amino acid sequence, we ran ORFfinder and chose the longest ORF among the all predicted ones.
>67383_67383_1_PPFIA1-ARHGAP32_PPFIA1_chr11_70118542_ENST00000253925_ARHGAP32_chr11_128963602_ENST00000310343_length(transcript)=10188nt_BP=479nt
GCCGCGCAGCCGGGCCCGCTCCTCCTCCGCTCCGCCAGTGTCCGGCCGCGGGCCGGCCTTAGTGACTGGGGCGGCGGGCCCCGGGGCCGC
GGCGTGGGGCGGGCAGGCGGACGCCGGCCGCGGGCTGCTTTCGTCGGCTCCCAAGCTCTCCCGGAGCGAGCAGCCGCCCGCGAGCCGCCG
CGGAGCCTCCTCGCCCGCTCCCGCCGGCGAGCAAGATGATGTGCGAGGTGATGCCGACCATCAGCGAAGCAGAAGGCCCCCCTGGAGGAG
GTGGAGGCCATGGTTCCGGCTCCCCTTCACAGCCAGATGCAGATTCACATTTTGAACAGTTGATGGTCTCCATGCTAGAAGAAAGGGACC
GCCTTCTTGATACACTGAGAGAGACTCAAGAAACGCTGGCCTTAACCCAGGGGAAGTTACACGAGGTTGGTCATGAAAGAGATTCCTTGC
AGAGACAGCTCAACACGGCACTTCCACAGCTTTCACTTTCAGAAGAACAGAATGAAGTAATGAAAAATGGCTGTGAATCTAAAGAGCTGG
TCTACCTCGTGCAGATTGCTTGTCAGGGAAAAAGTTGGATTGTTAAAAGAAGTTATGAAGATTTTCGGGTACTTGATAAACATCTTCATC
TGTGTATTTATGACCGAAGATTTTCCCAGCTCTCAGAACTTCCCCGTTCTGACACCCTGAAGGACAGTCCAGAGTCGGTCACTCAGATGC
TTATGGCTTACCTGTCACGCCTTTCAGCTATCGCTGGCAACAAGATCAACTGTGGGCCCGCCCTTACCTGGATGGAGATTGATAATAAGG
GAAATCACCTTTTGGTTCATGAGGAGTCATCCATCAACACTCCTGCTGTCGGTGCTGCCCATGTTATCAAGAGGTACACTGCTCGGGCCC
CTGACGAACTGACCTTAGAGGTGGGAGACATTGTTTCTGTTATTGACATGCCCCCGAAAGTGTTAAGCACATGGTGGAGAGGCAAGCACG
GATTCCAGGTGGGACTCTTCCCTGGACACTGTGTTGAGTTAATTAACCAAAAAGTTCCCCAGTCAGTGACCAACTCAGTGCCAAAACCAG
TGTCTAAAAAGCACGGCAAGCTCATTACGTTCTTACGAACATTCATGAAGTCTCGTCCAACAAAACAGAAGCTGAAGCAGCGGGGAATCT
TGAAAGAGAGGGTGTTTGGTTGTGACCTGGGGGAACACCTTCTAAATTCTGGTTTTGAAGTGCCGCAGGTTCTTCAAAGCTGCACAGCAT
TCATTGAGAGATATGGCATCGTGGATGGAATCTATCGCCTTTCTGGTGTTGCCTCCAATATCCAGAGACTACGCCATGAATTTGACTCTG
AGCACGTCCCCGACCTGACGAAAGAACCGTATGTTCAGGACATCCATTCTGTGGGTTCCCTATGTAAGCTGTACTTCCGGGAACTCCCAA
ACCCTCTGCTTACCTACCAGCTGTATGAGAAATTTTCTGATGCAGTTTCAGCAGCAACAGATGAAGAAAGGCTGATAAAAATCCACGATG
TCATCCAGCAGCTCCCCCCACCACACTACAGAACACTGGAGTTCCTGATGAGACACTTGTCTCTTCTAGCTGACTATTGTTCCATCACAA
ATATGCATGCAAAAAATCTAGCAATTGTTTGGGCTCCAAACCTGTTAAGATCAAAACAGATAGAATCTGCCTGCTTCAGTGGAACAGCAG
CTTTCATGGAAGTGAGGATTCAGTCTGTGGTTGTTGAGTTCATCCTGAATCACGTTGATGTGCTGTTCAGCGGCAGAATCAGCATGGCCA
TGCAAGAGGGGGCAGCTTCTCTATCAAGGCCCAAGTCCCTCCTGGTATCCTCTCCATCCACCAAACTGCTGACATTGGAAGAGGCCCAGG
CACGAACACAAGCTCAGGTCAATTCTCCAATTGTGACGGAAAATAAATATATCGAAGTAGGAGAAGGACCTGCTGCACTTCAGGGGAAAT
TTCATACCATAATTGAGTTCCCACTTGAAAGAAAGAGGCCTCAAAATAAGATGAAAAAGTCTCCTGTGGGTAGCTGGCGTTCCTTTTTCA
ACTTGGGGAAATCATCATCTGTTTCTAAACGAAAGCTGCAGCGGAATGAGAGTGAGCCTTCAGAGATGAAAGCCATGGCTCTGAAAGGTG
GCAGGGCAGAAGGAACCCTCCGTTCAGCTAAAAGTGAGGAGTCTCTTACATCTCTCCATGCAGTTGATGGTGATTCTAAGCTCTTCCGAC
CCAGAAGACCCAGATCTTCCAGTGATGCACTGTCTGCCTCTTTTAATGGAGAAATGCTGGGGAACCGCTGTAACTCCTATGATAATCTGC
CTCATGACAATGAGAGTGAGGAGGAAGGAGGGCTGCTTCATATCCCAGCCCTTATGTCTCCTCATTCAGCTGAGGATGTTGACTTGAGCC
CACCAGACATTGGAGTAGCCAGCCTGGATTTTGATCCAATGTCATTTCAATGTAGTCCTCCTAAGGCCGAATCAGAATGTCTGGAGAGTG
GTGCTTCCTTTTTAGATTCACCAGGATACTCCAAGGATAAACCAAGTGCCAATAAAAAGGATGCAGAAACAGGTAGTAGCCAATGTCAGA
CTCCAGGAAGCACAGCAAGCTCTGAACCTGTCTCTCCTCTTCAGGAGAAACTGAGTCCATTCTTTACCCTGGACTTGAGCCCAACTGAAG
ATAAATCATCTAAGCCATCCTCCTTTACTGAAAAGGTCGTCTATGCTTTCTCTCCGAAGATAGGACGGAAATTAAGCAAATCACCTTCTA
TGAGCATATCTGAGCCAATTTCAGTGACCCTACCACCACGGGTGTCAGAAGTCATTGGTACAGTCTCAAATACCACAGCTCAGAATGCAT
CATCTTCAACCTGGGACAAATGCGTTGAAGAAAGGGATGCCACAAATAGATCCCCCACCCAGATAGTAAAGATGAAAACAAATGAGACAG
TTGCCCAAGAAGCATATGAATCTGAAGTCCAGCCCCTGGACCAGGTGGCTGCTGAAGAAGTAGAATTGCCAGGGAAAGAGGATCAGTCTG
TCTCAAGCAGTCAGAGTAAGGCTGTAGCTTCTGGACAGACTCAGACAGGAGCAGTTACCCATGACCCCCCTCAGGATTCCGTTCCTGTCA
GTTCAGTCTCTCTTATCCCACCACCACCGCCTCCGAAAAATGTTGCCCGAATGTTGGCGCTAGCATTAGCTGAGTCCGCACAGCAAGCCT
CAACTCAGTCATTGAAGAGACCAGGGACCTCTCAGGCTGGGTATACAAATTATGGAGACATAGCGGTGGCTACAACTGAAGATAATCTGT
CCAGTTCTTACTCTGCAGTTGCTCTAGATAAGGCCTATTTCCAAACCGATCGACCAGCAGAGCAGTTCCACCTCCAGAATAATGCACCAG
GAAACTGTGACCATCCTCTACCAGAGACAACAGCTACTGGGGATCCTACCCATTCCAACACAACTGAATCTGGGGAGCAACATCACCAAG
TAGACTTAACAGGGAATCAGCCACATCAAGCATATTTATCTGGGGACCCAGAAAAGGCCAGAATTACTTCAGTTCCCTTAGACTCAGAGA
AGTCTGATGATCATGTAAGTTTCCCTGAAGACCAGTCTGGGAAGAACAGTATGCCAACTGTCTCCTTCTTGGATCAGGACCAGTCTCCAC
CCCGTTTCTACAGTGGAGATCAGCCTCCTTCTTATCTTGGTGCAAGTGTGGATAAACTCCATCACCCTTTAGAATTTGCAGACAAATCTC
CCACACCTCCTAATTTACCTAGCGATAAAATCTACCCTCCTTCTGGGTCCCCCGAAGAGAATACCAGCACAGCCACCATGACTTACATGA
CAACTACTCCAGCAACAGCCCAAATGAGCACCAAGGAAGCCAGCTGGGATGTGGCTGAACAACCCACCACTGCTGATTTTGCTGCTGCCA
CACTTCAGCGCACGCACAGAACTAATCGTCCCCTTCCCCCTCCGCCTTCCCAGAGATCTGCAGAGCAGCCACCAGTTGTGGGGCAGGTAC
AAGCAGCAACCAATATAGGATTAAATAATTCCCACAAGGTTCAAGGAGTAGTTCCAGTTCCAGAGAGGCCACCTGAACCTCGAGCCATGG
ATGACCCTGCGTCTGCCTTCATCAGTGACAGTGGTGCTGCTGCTGCTCAGTGTCCCATGGCTACAGCTGTCCAGCCAGGCCTGCCTGAGA
AAGTGCGGGACGGTGCCCGGGTCCCGCTGCTGCACCTGCGCGCCGAGTCTGTCCCTGCGCATCCCTGTGGCTTTCCTGCACCACTGCCCC
CCACCAGGATGATGGAGAGTAAGATGATTGCTGCCATACACTCCAGCAGTGCAGATGCCACCAGCAGTTCAAATTATCATTCCTTTGTCA
CTGCTTCATCCACCTCTGTGGACGATGCATTGCCTTTACCACTTCCTGTCCCACAACCTAAGCATGCTTCTCAGAAAACAGTTTACTCCT
CCTTTGCTAGGCCCGATGTCACCACTGAACCCTTTGGTCCAGATAACTGTTTGCATTTCAATATGACTCCAAACTGCCAGTACCGTCCCC
AGAGTGTACCTCCCCATCACAATAAATTGGAGCAGCACCAAGTGTATGGTGCCAGGTCAGAGCCACCAGCCTCCATGGGTCTTCGTTATA
ACACATATGTGGCCCCAGGAAGAAACGCATCTGGACACCACTCCAAGCCATGCAGCCGGGTCGAGTATGTGTCTTCTTTGAGCTCCTCTG
TCAGGAATACCTGTTACCCCGAAGACATTCCACCGTACCCTACCATCCGGAGAGTGCAGTCTCTCCATGCTCCGCCGTCTTCCATGATTC
GCTCTGTTCCCATTTCACGGACAGAAGTTCCCCCAGATGATGAGCCAGCCTACTGCCCAAGACCTCTGTACCAATATAAGCCATATCAGT
CCTCCCAGGCCCGCTCAGATTATCATGTCACTCAGCTTCAGCCTTACTTTGAGAATGGCCGGGTCCACTACAGGTATAGCCCATATTCCA
GTTCTTCTAGTTCCTATTACAGTCCAGATGGGGCCCTGTGTGATGTGGATGCCTATGGCACAGTCCAGTTGAGACCCCTTCACCGCCTTC
CCAATCGAGACTTTGCTTTCTACAATCCTAGGCTGCAAGGAAAGAGCTTGTACAGTTATGCTGGTTTGGCTCCACGTCCCCGGGCCAACG
TGACTGGCTATTTCTCTCCCAACGACCATAATGTAGTCAGCATGCCTCCGGCTGCTGATGTGAAGCACACCTACACCTCATGGGATCTTG
AGGACATGGAAAAATACCGCATGCAGTCCATCCGGAGAGAGAGCCGTGCTCGGCAGAAGGTGAAAGGGCCTGTCATGTCCCAATATGATA
ACATGACCCCGGCGGTGCAGGACGACTTGGGTGGGATCTATGTCATCCATCTGCGTAGTAAATCAGATCCTGGGAAAACTGGACTTCTCT
CAGTGGCAGAAGGAAAGGAGAGCCGCCATGCAGCCAAGGCCATCAGTCCCGAGGGAGAGGACCGCTTCTATAGGAGGCATCCCGAGGCAG
AGATGGACAGAGCCCACCATCACGGAGGCCATGGTAGCACGCAGCCGGAGAAGCCATCCCTGCCTCAGAAGCAGAGCAGCCTGAGGAGCA
GGAAGCTTCCTGACATGGGCTGCAGTCTTCCTGAGCACAGGGCACACCAAGAAGCAAGCCATAGGCAGTTCTGTGAGTCAAAGAATGGGC
CCCCTTATCCCCAGGGAGCTGGCCAGTTAGATTATGGGTCCAAAGGGATTCCAGACACTTCTGAGCCAGTCAGCTACCACAACTCTGGAG
TAAAATATGCTGCATCCGGGCAAGAATCTTTAAGACTGAACCACAAAGAGGTAAGGCTCTCCAAAGAGATGGAGCGACCCTGGGTTAGGC
AGCCTTCTGCCCCAGAGAAACACTCCAGAGACTGCTACAAGGAGGAAGAACACCTCACTCAGTCAATCGTCCCACCCCCTAAACCAGAGA
GGAGTCATAGCCTCAAACTCCATCATACCCAGAACGTGGAGAGGGACCCCAGTGTGCTGTACCAGTACCAACCACACGGCAAGCGCCAGA
GCAGTGTGACTGTTGTGTCCCAGTATGATAACCTGGAAGATTACCACTCCCTGCCTCAGCACCAGCGAGGAGTCTTTGGAGGGGGCGGCA
TGGGGACGTATGTGCCCCCTGGCTTTCCCCATCCACAGAGCAGGACCTATGCTACAGCGTTGGGTCAAGGGGCCTTCCTGCCCGCAGAGT
TGTCCTTGCAGCATCCTGAAACACAGATCCATGCAGAATGAGCCCTGCGAGCAATAGAGTTGAAGCAGCCTCTGCTGGACAGTGGACTGT
TCTATTTTTTTCAATAACCAAAAAGATTAAACAAAAAATACTATAAAACCCCTGACCACATTTAAAAAATGATAATAAAAGTAAACAAAT
CAGCATCTTTTTCCCCTTCCCTGCTTCATTACCCCCTCTTCCATCTATAGACTTTGTCATTTTTGTCTTTAGAAAAGATCTGAAGGATGG
TAAAGCCCCGTGCTGAAACCCAGTAGAGAAACCTGTCTCAGGACACACTTGCCATCTAGGGCTAGCTTGAAAGAGCCTGAGGACTGCCTT
TAACTGAATTTGAATTCAGCATTGTCCTTTCTTCTTAGTATTTGCTGCATAATTGAGAGCAGTTCACATCGATTTCCTGGTAGGCGTCTG
CATTCCCTGTTGTGTTCCTGCTTCTCCTTCAGTAGCTGCACAACTTGCGCAGATCGACACACTGTTGTCACTTCATTCTCCCCGTCTGAG
AAGGATCTTGTGTTCAGTTAGAGTCGTGGAAAAATCCCTGATCCTTCAAGGTCAGTCAGACAGTTGGCAACATTATAATTAAAAATAAGA
AATTAAGACTTTAAATTAAACATTTGGTAGAGTCATCATAAAACACCAGACCACTTAGACTCAGGCTGAACCATACTCTTTCTATTCTTA
TTTTTCATCCTTGTTCCTCACGGTTCAGTGAACAGGCTCATATCATGACAGAATGGACTTTTAAAAGTTAGTACTTAAGGAAACTTCTTT
AGGTGGAAGAAAGTAAAGTTCTTATTGTCAGTGAACTTTATTAGCACCAGAAATCTCTATTGATGCTTTTAATGCATTGCCTGCCTTCAG
GTTTTCTTCTTACCCCACCCCTCAATAAGATTTGGTGAATTGTAATTCTAGTAAAACATGTCATACCATTGGTTTTCCTAAATTATCAAC
TTTCTTTCATTAAAAAAAAAAAAAAAAAAAAAAGCCCAGCATGGTTTGACTGGATAGACACGCATAATTTATTATGAATATAAATTTCCA
TGTTTGTTTCTGTTCCTAAACCAGAGTACGAGGTCCCTGGGAATTTAAGTAGCTACGCATTATCTATTATTAGACTGCAAGTTCCTGCAA
TAACTGCTTAGTTCACAGCCCCGTTTCACCAGTGGAGTTCTGGGCAGTTATTGCTGTCCTAAGGCATTACTGTCGTTTGCTTACTCTATA
CTTGTGTGGTCACAGTCTTCTTGTAATTACCATCTACACCAGCATTTCAGGTATAGCTCTTTATAACTCTGGAGACATGTAAAACATGTT
TAACACCCACGAGTTTTGAAAGTTGCATTCCTTATTAGAGTAGGAACTCTCTAGCCCAACTCCATTCTATGTTCTCAGCTCCCTCCACCC
CCCAAAATACATCAGACTAGCAAGGCAGTCCTATGTTTACAAAACGAGTTTAGATTGTCATTTCATTCCATAACTCTTAATAATACTCAA
GTTTTATACATTCACGTATTTTAAATGCTCGGTCTGTAGAAGACACTAGGAGAATTGCATTCCAATTACTGGATGGTTGCTGCTCTGGCT
TTTTAGAACTTGAAATTAATTTTTATTTAGAGCAAAGGAGGAAATCTTTTAAGAGGCTAAAATCATGCTGCTATTATTGCTGTGAAATTG
TATAAAGATTAGGATTCATGCCAGTTTTTATTTTAAAAAATAATGTGCATTTTAAGGGTTTATATTTAGAAAAAAATAAAATGTTTCAAG
AACAACACATTGATATGTGGAAATATTCTATAAGGTTTTCTTTTGTTCCCTTAGAATTCATTGGAGGGATGCAGTAAAAACTGTAGTAGA
AACCTTGAAACACCCATATGTGAAAAGGTCTGTGGAAATTGAGGCCTCTACATTAAAAGTGCAGAACCAACTGTTTTACAGTCAAAGTGC
TAGGAAACCTGATAGGATACTTCCCTTTGGCACAAAAACACCCTGGGTGCTACATACAGGAGTATGACCTTTGGTGAATATGTGGCACTA
ATTTTTTTTACCTTAATCATATTCTTGTCAAGTAGGCAACCCATTGCCCCTTGGAGACCACACCAGCCCTGTAAGTTCTCACCAGCAGCA
TGGAGATTAGGAAGAGGGGCTGCTGTGACCAGGAGATACACACGGCTTTAAGTAACTGAGAGCCTAAAGAAAGTAACCCAGGGAGTCCGG
TCCAGTTTTAATATTTGTGGATTTGTTGTCACACACATTGTTTAGTCCTGAAACTAAAACCTATTTTATAAATAGTAGGGTTAATTCCTC
GAAACAATTTCTTTATTAATAAATGTCCTGTGGGTTTAGAAATATCAGGTAAATATTTGAATACAGAATGATGATTGCAATTACTGTTAC
AAGCGTGAAACACAAACTTCAGATCAAATCTAGAGTTGCTTCATTTAATGCATGCTAGCAACAGCCTTAACTTTGGATTCAGTTATTTGA
AACACTTTTCCGGCATCTTTCCCTTTCTAATGTTGTGGGGTGGAAACCGGATGGCAAATCACTGTGAGCCGGATACCTCAGCACAGTCCA
CCTTGTGTGTGACTTCACAAATGGGGGACTTCACAAATGGGGTAACTGAATGTTATTACTTTCAAATTTTGACATGGAGCATTATGATCA
AGGAAATGGAGCTGCCTTATACATTAAACCCGTGATTTAATCCTATTGACATTTTCATAGCCATGCCTCCAGATTTTATCTTTTTGGCAA
AATTCTGATTCCACAGTTTGGTCTGATTGAAATAAATATTCCCTGGACGTCTGGCTAAAAATTTTGCTAACAATCCCAGAGGTGCCATTT
TCTTATTAATAAATTTCATTGGAGCCTTATTTCTTACTATATTCAATTTCGTTTCAAACCTGCAAGTCCCTGGGATGGTCCCACGACTAG
GGCCTGCACATTTCTTACAATGGCAAAGCATTTTTTAAAATTTAGGGTCAGGTTGAAAAATTCTAGGACTAATTCTGTAGAGAGGAGGGA
CTGTTAACTAACGTGAGTGGGGACGGAGGAGTAGGTTACCACATTTGGAGCAGTAATAGATGCAAACGATGTAAATTTGAAATTTGCCCC
TTTAGTTAAAGAAGGAGCCTGCAAAGTCCATTTCTCTGTTTTCAGCCCTGTCAGTCACCCATTTAGGATGTTGGCAAAGTACTGCTTGAG
CAGAATGTGTAAGAAAGTAATAATGAAAGCAAAAGTATGTCAGACAGTTACTTCTTCCACATGGTTAGAGGCATGTGATTTTCAGCACTG
TGTGTTACAGAAATGTCAGGAATGGTGTATTATAACGTGTGCAAGATAATGTCAGTGTGCACAGAGGGTCTTTTTTCCTTATCTGATTAG
TACTGTTAATGTTCAAAGAATAAAAATGGTTTTACAGTTTAGATTCTGAGATAGCAAAACCTGATTTTTCAACCATGACCTGCATGAGAG
AAGCATCCTAGGAAGTCTTAGATCATACTTTTGAGTTTTTAATTTTAATTTATATAGTGTTTTTTTATGTCTTAATATTTTTGTGAACTG
GTGTAAATTGTTAATGCATATAAGCTTGTGTATTTTTGTAAATAGTTTTGTGATTTATTTCTTGCCCCATATGTAAATATTTAGAGTCTC
ATTTCTTGCAAACTTATTTGAAGCTGAGTTGTGGGTTTGGGTTTTGTTTGTTTCTTTGGTTGCAGGGTGGGGTGGGGGGTGGCAGGGGAG
GGAGGAAGGGATTTTTGTACCTGGAGATGGAGATATCTTGTGGTTTAAAGCAAATGTCCCACTGAAAGTGATTCAAATATCAACAGAATT

>67383_67383_1_PPFIA1-ARHGAP32_PPFIA1_chr11_70118542_ENST00000253925_ARHGAP32_chr11_128963602_ENST00000310343_length(amino acids)=2091AA_BP=138
MGRRAPGPRRGAGRRTPAAGCFRRLPSSPGASSRPRAAAEPPRPLPPASKMMCEVMPTISEAEGPPGGGGGHGSGSPSQPDADSHFEQLM
VSMLEERDRLLDTLRETQETLALTQGKLHEVGHERDSLQRQLNTALPQLSLSEEQNEVMKNGCESKELVYLVQIACQGKSWIVKRSYEDF
RVLDKHLHLCIYDRRFSQLSELPRSDTLKDSPESVTQMLMAYLSRLSAIAGNKINCGPALTWMEIDNKGNHLLVHEESSINTPAVGAAHV
IKRYTARAPDELTLEVGDIVSVIDMPPKVLSTWWRGKHGFQVGLFPGHCVELINQKVPQSVTNSVPKPVSKKHGKLITFLRTFMKSRPTK
QKLKQRGILKERVFGCDLGEHLLNSGFEVPQVLQSCTAFIERYGIVDGIYRLSGVASNIQRLRHEFDSEHVPDLTKEPYVQDIHSVGSLC
KLYFRELPNPLLTYQLYEKFSDAVSAATDEERLIKIHDVIQQLPPPHYRTLEFLMRHLSLLADYCSITNMHAKNLAIVWAPNLLRSKQIE
SACFSGTAAFMEVRIQSVVVEFILNHVDVLFSGRISMAMQEGAASLSRPKSLLVSSPSTKLLTLEEAQARTQAQVNSPIVTENKYIEVGE
GPAALQGKFHTIIEFPLERKRPQNKMKKSPVGSWRSFFNLGKSSSVSKRKLQRNESEPSEMKAMALKGGRAEGTLRSAKSEESLTSLHAV
DGDSKLFRPRRPRSSSDALSASFNGEMLGNRCNSYDNLPHDNESEEEGGLLHIPALMSPHSAEDVDLSPPDIGVASLDFDPMSFQCSPPK
AESECLESGASFLDSPGYSKDKPSANKKDAETGSSQCQTPGSTASSEPVSPLQEKLSPFFTLDLSPTEDKSSKPSSFTEKVVYAFSPKIG
RKLSKSPSMSISEPISVTLPPRVSEVIGTVSNTTAQNASSSTWDKCVEERDATNRSPTQIVKMKTNETVAQEAYESEVQPLDQVAAEEVE
LPGKEDQSVSSSQSKAVASGQTQTGAVTHDPPQDSVPVSSVSLIPPPPPPKNVARMLALALAESAQQASTQSLKRPGTSQAGYTNYGDIA
VATTEDNLSSSYSAVALDKAYFQTDRPAEQFHLQNNAPGNCDHPLPETTATGDPTHSNTTESGEQHHQVDLTGNQPHQAYLSGDPEKARI
TSVPLDSEKSDDHVSFPEDQSGKNSMPTVSFLDQDQSPPRFYSGDQPPSYLGASVDKLHHPLEFADKSPTPPNLPSDKIYPPSGSPEENT
STATMTYMTTTPATAQMSTKEASWDVAEQPTTADFAAATLQRTHRTNRPLPPPPSQRSAEQPPVVGQVQAATNIGLNNSHKVQGVVPVPE
RPPEPRAMDDPASAFISDSGAAAAQCPMATAVQPGLPEKVRDGARVPLLHLRAESVPAHPCGFPAPLPPTRMMESKMIAAIHSSSADATS
SSNYHSFVTASSTSVDDALPLPLPVPQPKHASQKTVYSSFARPDVTTEPFGPDNCLHFNMTPNCQYRPQSVPPHHNKLEQHQVYGARSEP
PASMGLRYNTYVAPGRNASGHHSKPCSRVEYVSSLSSSVRNTCYPEDIPPYPTIRRVQSLHAPPSSMIRSVPISRTEVPPDDEPAYCPRP
LYQYKPYQSSQARSDYHVTQLQPYFENGRVHYRYSPYSSSSSSYYSPDGALCDVDAYGTVQLRPLHRLPNRDFAFYNPRLQGKSLYSYAG
LAPRPRANVTGYFSPNDHNVVSMPPAADVKHTYTSWDLEDMEKYRMQSIRRESRARQKVKGPVMSQYDNMTPAVQDDLGGIYVIHLRSKS
DPGKTGLLSVAEGKESRHAAKAISPEGEDRFYRRHPEAEMDRAHHHGGHGSTQPEKPSLPQKQSSLRSRKLPDMGCSLPEHRAHQEASHR
QFCESKNGPPYPQGAGQLDYGSKGIPDTSEPVSYHNSGVKYAASGQESLRLNHKEVRLSKEMERPWVRQPSAPEKHSRDCYKEEEHLTQS
IVPPPKPERSHSLKLHHTQNVERDPSVLYQYQPHGKRQSSVTVVSQYDNLEDYHSLPQHQRGVFGGGGMGTYVPPGFPHPQSRTYATALG

--------------------------------------------------------------
>67383_67383_2_PPFIA1-ARHGAP32_PPFIA1_chr11_70118542_ENST00000253925_ARHGAP32_chr11_128963602_ENST00000524655_length(transcript)=8469nt_BP=479nt
GCCGCGCAGCCGGGCCCGCTCCTCCTCCGCTCCGCCAGTGTCCGGCCGCGGGCCGGCCTTAGTGACTGGGGCGGCGGGCCCCGGGGCCGC
GGCGTGGGGCGGGCAGGCGGACGCCGGCCGCGGGCTGCTTTCGTCGGCTCCCAAGCTCTCCCGGAGCGAGCAGCCGCCCGCGAGCCGCCG
CGGAGCCTCCTCGCCCGCTCCCGCCGGCGAGCAAGATGATGTGCGAGGTGATGCCGACCATCAGCGAAGCAGAAGGCCCCCCTGGAGGAG
GTGGAGGCCATGGTTCCGGCTCCCCTTCACAGCCAGATGCAGATTCACATTTTGAACAGTTGATGGTCTCCATGCTAGAAGAAAGGGACC
GCCTTCTTGATACACTGAGAGAGACTCAAGAAACGCTGGCCTTAACCCAGGGGAAGTTACACGAGGTTGGTCATGAAAGAGATTCCTTGC
AGAGACAGCTCAACACGGCACTTCCACAGCTTTCACTTTCAGAAGAACAGAATGAAGTAATGAAAAATGGCTGTGAATCTAAAGAGCTGG
TCTACCTCGTGCAGATTGCTTGTCAGGGAAAAAGTTGGATTGTTAAAAGAAGTTATGAAGATTTTCGGGTACTTGATAAACATCTTCATC
TGTGTATTTATGACCGAAGATTTTCCCAGCTCTCAGAACTTCCCCGTTCTGACACCCTGAAGGACAGTCCAGAGTCGGTCACTCAGATGC
TTATGGCTTACCTGTCACGCCTTTCAGCTATCGCTGGCAACAAGATCAACTGTGGGCCCGCCCTTACCTGGATGGAGATTGATAATAAGG
GAAATCACCTTTTGGTTCATGAGGAGTCATCCATCAACACTCCTGCTGTCGGTGCTGCCCATGTTATCAAGAGGTACACTGCTCGGGCCC
CTGACGAACTGACCTTAGAGGTGGGAGACATTGTTTCTGTTATTGACATGCCCCCGAAAGTGTTAAGCACATGGTGGAGAGGCAAGCACG
GATTCCAGGTGGGACTCTTCCCTGGACACTGTGTTGAGTTAATTAACCAAAAAGTTCCCCAGTCAGTGACCAACTCAGTGCCAAAACCAG
TGTCTAAAAAGCACGGCAAGCTCATTACGTTCTTACGAACATTCATGAAGTCTCGTCCAACAAAACAGAAGCTGAAGCAGCGGGGAATCT
TGAAAGAGAGGGTGTTTGGTTGTGACCTGGGGGAACACCTTCTAAATTCTGGTTTTGAAGTGCCGCAGGTTCTTCAAAGCTGCACAGCAT
TCATTGAGAGATATGGCATCGTGGATGGAATCTATCGCCTTTCTGGTGTTGCCTCCAATATCCAGAGACTACGCCATGAATTTGACTCTG
AGCACGTCCCCGACCTGACGAAAGAACCGTATGTTCAGGACATCCATTCTGTGGGTTCCCTATGTAAGCTGTACTTCCGGGAACTCCCAA
ACCCTCTGCTTACCTACCAGCTGTATGAGAAATTTTCTGATGCAGTTTCAGCAGCAACAGATGAAGAAAGGCTGATAAAAATCCACGATG
TCATCCAGCAGCTCCCCCCACCACACTACAGAACACTGGAGTTCCTGATGAGACACTTGTCTCTTCTAGCTGACTATTGTTCCATCACAA
ATATGCATGCAAAAAATCTAGCAATTGTTTGGGCTCCAAACCTGTTAAGATCAAAACAGATAGAATCTGCCTGCTTCAGTGGAACAGCAG
CTTTCATGGAAGTGAGGATTCAGTCTGTGGTTGTTGAGTTCATCCTGAATCACGTTGATGTGCTGTTCAGCGGCAGAATCAGCATGGCCA
TGCAAGAGGGGGCAGCTTCTCTATCAAGGCCCAAGTCCCTCCTGGTATCCTCTCCATCCACCAAACTGCTGACATTGGAAGAGGCCCAGG
CACGAACACAAGCTCAGGTCAATTCTCCAATTGTGACGGAAAATAAATATATCGAAGTAGGAGAAGGACCTGCTGCACTTCAGGGGAAAT
TTCATACCATAATTGAGTTCCCACTTGAAAGAAAGAGGCCTCAAAATAAGATGAAAAAGTCTCCTGTGGGTAGCTGGCGTTCCTTTTTCA
ACTTGGGGAAATCATCATCTGTTTCTAAACGAAAGCTGCAGCGGAATGAGAGTGAGCCTTCAGAGATGAAAGCCATGGCTCTGAAAGGTG
GCAGGGCAGAAGGAACCCTCCGTTCAGCTAAAAGTGAGGAGTCTCTTACATCTCTCCATGCAGTTGATGGTGATTCTAAGCTCTTCCGAC
CCAGAAGACCCAGATCTTCCAGTGATGCACTGTCTGCCTCTTTTAATGGAGAAATGCTGGGGAACCGCTGTAACTCCTATGATAATCTGC
CTCATGACAATGAGAGTGAGGAGGAAGGAGGGCTGCTTCATATCCCAGCCCTTATGTCTCCTCATTCAGCTGAGGATGTTGACTTGAGCC
CACCAGACATTGGAGTAGCCAGCCTGGATTTTGATCCAATGTCATTTCAATGTAGTCCTCCTAAGGCCGAATCAGAATGTCTGGAGAGTG
GTGCTTCCTTTTTAGATTCACCAGGATACTCCAAGGATAAACCAAGTGCCAATAAAAAGGATGCAGAAACAGGTAGTAGCCAATGTCAGA
CTCCAGGAAGCACAGCAAGCTCTGAACCTGTCTCTCCTCTTCAGGAGAAACTGAGTCCATTCTTTACCCTGGACTTGAGCCCAACTGAAG
ATAAATCATCTAAGCCATCCTCCTTTACTGAAAAGGTCGTCTATGCTTTCTCTCCGAAGATAGGACGGAAATTAAGCAAATCACCTTCTA
TGAGCATATCTGAGCCAATTTCAGTGACCCTACCACCACGGGTGTCAGAAGTCATTGGTACAGTCTCAAATACCACAGCTCAGAATGCAT
CATCTTCAACCTGGGACAAATGCGTTGAAGAAAGGGATGCCACAAATAGATCCCCCACCCAGATAGTAAAGATGAAAACAAATGAGACAG
TTGCCCAAGAAGCATATGAATCTGAAGTCCAGCCCCTGGACCAGGTGGCTGCTGAAGAAGTAGAATTGCCAGGGAAAGAGGATCAGTCTG
TCTCAAGCAGTCAGAGTAAGGCTGTAGCTTCTGGACAGACTCAGACAGGTACCGTTTGTTTTCCTCCATTCTTTCTTTAAGTTAAGAGGG
ATCTTCAATCCTGTGTGCCATCTGTGCCTTTTAAGAGAGAAATTTGTCCACAGCTAGCCTTTAATCAAAGAGAATGCTTTTCTGGGTGGT
GCTGATGGCTCAGAGCCCTAAATTAAAAGCAGTCCAACAAAACTCCCCAAAAGGGCCAATGGTCCTGCTTCAAATCTTCACAAAAGTCCC
CTTATCTCTTTGGACGGTGAGAATTCGTGGATAATTTTTGCACAACTGCGTAGCTCTTGATTCTGTTTTTCTCTTCTAATAAAATATCTT
TATTGTAGCCTTCCAAGTTAACAAGCCAGCTACACCATCAAATGTAAAAACTGTTCATAATAACAGTCTACAAGCACTTGAAGCTTGTTT
TCTAAGCAATCTTTTCTGAGCCAGGTGAGGGACATGCTTTTTTTCCCCCCCATCTCTGTAACAATTCAAGAAGAGATTGCAGTCTTTATA
CACTGTTTGTTTTAGTTTTCCTTCTGAACCAGATGTGTTTTCAACAGCATTTGCATGTGGGATAGAAGATCATGGATTGCCATTTTGAAA
TATGGAAGGCACCTATTTTTTAATGATCACATGGGGAGTGTTTGGCTTTCCATTTAGGATAACGTAAGCTACCTTTTCACTCTCATTTTT
TTTCCCAATTTCCCACTAGGAGCAGTTACCCATGACCCCCCTCAGGATTCCGTTCCTGTCAGTTCAGTCTCTCTTATCCCACCACCACCG
CCTCCGAAAAATGTTGCCCGAATGTTGGCGCTAGCATTAGCTGAGTCCGCACAGCAAGCCTCAACTCAGTCATTGAAGAGACCAGGGACC
TCTCAGGCTGGGTATACAAATTATGGAGACATAGCGGTGGCTACAACTGAAGATAATCTGTCCAGTTCTTACTCTGCAGTTGCTCTAGAT
AAGGCCTATTTCCAAACCGATCGACCAGCAGAGCAGTTCCACCTCCAGAATAATGCACCAGGAAACTGTGACCATCCTCTACCAGAGACA
ACAGCTACTGGGGATCCTACCCATTCCAACACAACTGAATCTGGGGAGCAACATCACCAAGTAGACTTAACAGGGAATCAGCCACATCAA
GCATATTTATCTGGGGACCCAGAAAAGGCCAGAATTACTTCAGTTCCCTTAGACTCAGAGAAGTCTGATGATCATGTAAGTTTCCCTGAA
GACCAGTCTGGGAAGAACAGTATGCCAACTGTCTCCTTCTTGGATCAGGACCAGTCTCCACCCCGTTTCTACAGTGGAGATCAGCCTCCT
TCTTATCTTGGTGCAAGTGTGGATAAACTCCATCACCCTTTAGAATTTGCAGACAAATCTCCCACACCTCCTAATTTACCTAGCGATAAA
ATCTACCCTCCTTCTGGGTCCCCCGAAGAGAATACCAGCACAGCCACCATGACTTACATGACAACTACTCCAGCAACAGCCCAAATGAGC
ACCAAGGAAGCCAGCTGGGATGTGGCTGAACAACCCACCACTGCTGATTTTGCTGCTGCCACACTTCAGCGCACGCACAGAACTAATCGT
CCCCTTCCCCCTCCGCCTTCCCAGAGATCTGCAGAGCAGCCACCAGTTGTGGGGCAGGTACAAGCAGCAACCAATATAGGATTAAATAAT
TCCCACAAGGTAAGAAGGGGAAGATATCAGTGAGATGAAATATACTATTACCAAAGGTATGTCACTTTTCAGCAGGGTGTGTTGTTATCT
TTGAGTCAGACACAACAATTACTTTTAAGCCCTGTGGCTGGTTTCCATGAGATAGTTCCCATTTGAGGTTGGAGTCTGCCATTACCTTGA
TGCTGGCTTTTCCCCAGGAAAGGAGTAGCTCCTAGATGACTATAGCTTAACTGTACCTGCTCCCTTTTCTTCCTAAAGTGTCTCGGTAGT
TTATTCCAGTAACACAAAGAGATCAGGATCAAATGAGACAAAGTGGGCTTTACGGTTGTGGGTTGCTTTTTCTTATTTTTTTCCAACTCC
ATCACTGACTCATTGTGACTTTGGGCAAGTCATTTACCTACCCTCTGCCAATTATTCACAGTTACACAATGAAAATACTTCATTCTCAAA
ACATTCGTAAGACTGTCTGCCTTGCAGACTTTTTGGAAGTATAAGAGATTATAGTGCCTTGGGATTTTTTGTTACTTTCCTAGCATTCAC
CAGCAGTTTGTCCCATAGTCAGGTGCCTGTTTCAATGAGAGAATGTAGTATGCAGAATGCTAAGGTTTCTTCCTGAATTTCCTCATATTT
TAAGAAAGTGCCACAGGTTGTTTTTCTTCTATATGGTCACCTTGAACTATTAATAGGACTTAAGATTTTAGACCTTAGTGGAGGATGCTG
TGTTTACTGCTTCTCAAGGATAGCATGTTTTCAGTATGAGGATTATCTTTGGCCAGACTAAGGTGGAATCAAAGGTAGGAGAGAGGCAGT
AGCTTCTGATTTGAATATTGCCTTTCCCTATGTTTGAAGCCCTAAAACTGCTAACTGTGTACAACTGTGAATTTCAAAAGTCTCCCCAGA
TGATAGAATTAACTCTTAATTTAACAAGATGTCCTTTGTGTTGAGACTGAGCTAGACTAATAGACCGGGTATGTATTTTTAAGCTCTACA
GCATTACTTGACTAAACCTCTCTTTTGGTTTGTATATTAAAATTATGCCATAGGCAACCTCATCTCGCATTTAAAACCTCTCATAAATTA
GAAAACTTTGAATGGTTCTCCAAAGATAATACTGGGTGTTGTACAAAATAGCAGCACAAGCCTTCTTTTCCTAGAAATGGGTACAGATTC
ATTGCAACCACATGGCTTGGGAAAGTTCAAGCTGCTACCCAACCAGCCTTAATTTGTGAGTTACAAATTTAATAGTACTTGATTCATAGA
GGGAACAAAAAATAGACCCATAGTATTATCATCTTTCAATAGGTTCAAGGAGTAGTTCCAGTTCCAGAGAGGCCACCTGAACCTCGAGCC
ATGGATGACCCTGCGTCTGCCTTCATCAGTGACAGTGGTGCTGCTGCTGCTCAGTGTCCCATGGCTACAGCTGTCCAGCCAGGCCTGCCT
GAGAAAGTGCGGGACGGTGCCCGGGTCCCGCTGCTGCACCTGCGCGCCGAGTCTGTCCCTGCGCATCCCTGTGGCTTTCCTGCACCACTG
CCCCCCACCAGGATGATGGAGAGTAAGATGATTGCTGCCATACACTCCAGCAGTGCAGATGCCACCAGCAGTTCAAATTATCATTCCTTT
GTCACTGCTTCATCCACCTCTGTGGACGATGCATTGCCTTTACCACTTCCTGTCCCACAACCTAAGCATGCTTCTCAGAAAACAGTTTAC
TCCTCCTTTGCTAGGCCCGATGTCACCACTGAACCCTTTGGTCCAGATAACTGTTTGCATTTCAATATGACTCCAAACTGCCAGTACCGT
CCCCAGAGTGTACCTCCCCATCACAATAAATTGGAGCAGCACCAAGTGTATGGTGCCAGGTCAGAGCCACCAGCCTCCATGGGTCTTCGT
TATAACACATATGTGGCCCCAGGAAGAAACGCATCTGGACACCACTCCAAGCCATGCAGCCGGGTCGAGTATGTGTCTTCTTTGAGCTCC
TCTGTCAGGAATACCTGTTACCCCGAAGACATTCCACCGTACCCTACCATCCGGAGAGTGCAGTCTCTCCATGCTCCGCCGTCTTCCATG
ATTCGCTCTGTTCCCATTTCACGGACAGAAGTTCCCCCAGATGATGAGCCAGCCTACTGCCCAAGACCTCTGTACCAATATAAGCCATAT
CAGTCCTCCCAGGCCCGCTCAGATTATCATGTCACTCAGCTTCAGCCTTACTTTGAGAATGGCCGGGTCCACTACAGGTATAGCCCATAT
TCCAGTTCTTCTAGTTCCTATTACAGTCCAGATGGGGCCCTGTGTGATGTGGATGCCTATGGCACAGTCCAGTTGAGACCCCTTCACCGC
CTTCCCAATCGAGACTTTGCTTTCTACAATCCTAGGCTGCAAGGAAAGAGCTTGTACAGTTATGCTGGTTTGGCTCCACGTCCCCGGGCC
AACGTGACTGGCTATTTCTCTCCCAACGACCATAATGTAGTCAGCATGCCTCCGGCTGCTGATGTGAAGCACACCTACACCTCATGGGAT
CTTGAGGACATGGAAAAATACCGCATGCAGTCCATCCGGAGAGAGAGCCGTGCTCGGCAGAAGGTGAAAGGGCCTGTCATGTCCCAATAT
GATAACATGACCCCGGCGGTGCAGGACGACTTGGGTGGGATCTATGTCATCCATCTGCGTAGTAAATCAGATCCTGGGAAAACTGGACTT
CTCTCAGTGGCAGAAGGAAAGGAGAGCCGCCATGCAGCCAAGGCCATCAGTCCCGAGGGAGAGGACCGCTTCTATAGGAGGCATCCCGAG
GCAGAGATGGACAGAGCCCACCATCACGGAGGCCATGGTAGCACGCAGCCGGAGAAGCCATCCCTGCCTCAGAAGCAGAGCAGCCTGAGG
AGCAGGAAGCTTCCTGACATGGGCTGCAGTCTTCCTGAGCACAGGGCACACCAAGAAGCAAGCCATAGGCAGTTCTGTGAGTCAAAGAAT
GGGCCCCCTTATCCCCAGGGAGCTGGCCAGTTAGATTATGGGTCCAAAGGGATTCCAGACACTTCTGAGCCAGTCAGCTACCACAACTCT
GGAGTAAAATATGCTGCATCCGGGCAAGAATCTTTAAGACTGAACCACAAAGAGGTAAGGCTCTCCAAAGAGATGGAGCGACCCTGGGTT
AGGCAGCCTTCTGCCCCAGAGAAACACTCCAGAGACTGCTACAAGGAGGAAGAACACCTCACTCAGTCAATCGTCCCACCCCCTAAACCA
GAGAGGAGTCATAGCCTCAAACTCCATCATACCCAGAACGTGGAGAGGGACCCCAGTGTGCTGTACCAGTACCAACCACACGGCAAGCGC
CAGAGCAGTGTGACTGTTGTGTCCCAGTATGATAACCTGGAAGATTACCACTCCCTGCCTCAGCACCAGCGAGGAGTCTTTGGAGGGGGC
GGCATGGGGACGTATGTGCCCCCTGGCTTTCCCCATCCACAGAGCAGGACCTATGCTACAGCGTTGGGTCAAGGGGCCTTCCTGCCCGCA
GAGTTGTCCTTGCAGCATCCTGAAACACAGATCCATGCAGAATGAGCCCTGCGAGCAATAGAGTTGAAGCAGCCTCTGCTGGACAGTGGA
CTGTTCTATTTTTTTCAATAACCAAAAAGATTAAACAAAAAATACTATAAAACCCCTGACCACATTTAAAAAATGATAATAAAAGTAAAC

>67383_67383_2_PPFIA1-ARHGAP32_PPFIA1_chr11_70118542_ENST00000253925_ARHGAP32_chr11_128963602_ENST00000524655_length(amino acids)=1024AA_BP=138
MGRRAPGPRRGAGRRTPAAGCFRRLPSSPGASSRPRAAAEPPRPLPPASKMMCEVMPTISEAEGPPGGGGGHGSGSPSQPDADSHFEQLM
VSMLEERDRLLDTLRETQETLALTQGKLHEVGHERDSLQRQLNTALPQLSLSEEQNEVMKNGCESKELVYLVQIACQGKSWIVKRSYEDF
RVLDKHLHLCIYDRRFSQLSELPRSDTLKDSPESVTQMLMAYLSRLSAIAGNKINCGPALTWMEIDNKGNHLLVHEESSINTPAVGAAHV
IKRYTARAPDELTLEVGDIVSVIDMPPKVLSTWWRGKHGFQVGLFPGHCVELINQKVPQSVTNSVPKPVSKKHGKLITFLRTFMKSRPTK
QKLKQRGILKERVFGCDLGEHLLNSGFEVPQVLQSCTAFIERYGIVDGIYRLSGVASNIQRLRHEFDSEHVPDLTKEPYVQDIHSVGSLC
KLYFRELPNPLLTYQLYEKFSDAVSAATDEERLIKIHDVIQQLPPPHYRTLEFLMRHLSLLADYCSITNMHAKNLAIVWAPNLLRSKQIE
SACFSGTAAFMEVRIQSVVVEFILNHVDVLFSGRISMAMQEGAASLSRPKSLLVSSPSTKLLTLEEAQARTQAQVNSPIVTENKYIEVGE
GPAALQGKFHTIIEFPLERKRPQNKMKKSPVGSWRSFFNLGKSSSVSKRKLQRNESEPSEMKAMALKGGRAEGTLRSAKSEESLTSLHAV
DGDSKLFRPRRPRSSSDALSASFNGEMLGNRCNSYDNLPHDNESEEEGGLLHIPALMSPHSAEDVDLSPPDIGVASLDFDPMSFQCSPPK
AESECLESGASFLDSPGYSKDKPSANKKDAETGSSQCQTPGSTASSEPVSPLQEKLSPFFTLDLSPTEDKSSKPSSFTEKVVYAFSPKIG
RKLSKSPSMSISEPISVTLPPRVSEVIGTVSNTTAQNASSSTWDKCVEERDATNRSPTQIVKMKTNETVAQEAYESEVQPLDQVAAEEVE

--------------------------------------------------------------
>67383_67383_3_PPFIA1-ARHGAP32_PPFIA1_chr11_70118542_ENST00000389547_ARHGAP32_chr11_128963602_ENST00000310343_length(transcript)=10171nt_BP=462nt
GCTCCTCCTCCGCTCCGCCAGTGTCCGGCCGCGGGCCGGCCTTAGTGACTGGGGCGGCGGGCCCCGGGGCCGCGGCGTGGGGCGGGCAGG
CGGACGCCGGCCGCGGGCTGCTTTCGTCGGCTCCCAAGCTCTCCCGGAGCGAGCAGCCGCCCGCGAGCCGCCGCGGAGCCTCCTCGCCCG
CTCCCGCCGGCGAGCAAGATGATGTGCGAGGTGATGCCGACCATCAGCGAAGCAGAAGGCCCCCCTGGAGGAGGTGGAGGCCATGGTTCC
GGCTCCCCTTCACAGCCAGATGCAGATTCACATTTTGAACAGTTGATGGTCTCCATGCTAGAAGAAAGGGACCGCCTTCTTGATACACTG
AGAGAGACTCAAGAAACGCTGGCCTTAACCCAGGGGAAGTTACACGAGGTTGGTCATGAAAGAGATTCCTTGCAGAGACAGCTCAACACG
GCACTTCCACAGCTTTCACTTTCAGAAGAACAGAATGAAGTAATGAAAAATGGCTGTGAATCTAAAGAGCTGGTCTACCTCGTGCAGATT
GCTTGTCAGGGAAAAAGTTGGATTGTTAAAAGAAGTTATGAAGATTTTCGGGTACTTGATAAACATCTTCATCTGTGTATTTATGACCGA
AGATTTTCCCAGCTCTCAGAACTTCCCCGTTCTGACACCCTGAAGGACAGTCCAGAGTCGGTCACTCAGATGCTTATGGCTTACCTGTCA
CGCCTTTCAGCTATCGCTGGCAACAAGATCAACTGTGGGCCCGCCCTTACCTGGATGGAGATTGATAATAAGGGAAATCACCTTTTGGTT
CATGAGGAGTCATCCATCAACACTCCTGCTGTCGGTGCTGCCCATGTTATCAAGAGGTACACTGCTCGGGCCCCTGACGAACTGACCTTA
GAGGTGGGAGACATTGTTTCTGTTATTGACATGCCCCCGAAAGTGTTAAGCACATGGTGGAGAGGCAAGCACGGATTCCAGGTGGGACTC
TTCCCTGGACACTGTGTTGAGTTAATTAACCAAAAAGTTCCCCAGTCAGTGACCAACTCAGTGCCAAAACCAGTGTCTAAAAAGCACGGC
AAGCTCATTACGTTCTTACGAACATTCATGAAGTCTCGTCCAACAAAACAGAAGCTGAAGCAGCGGGGAATCTTGAAAGAGAGGGTGTTT
GGTTGTGACCTGGGGGAACACCTTCTAAATTCTGGTTTTGAAGTGCCGCAGGTTCTTCAAAGCTGCACAGCATTCATTGAGAGATATGGC
ATCGTGGATGGAATCTATCGCCTTTCTGGTGTTGCCTCCAATATCCAGAGACTACGCCATGAATTTGACTCTGAGCACGTCCCCGACCTG
ACGAAAGAACCGTATGTTCAGGACATCCATTCTGTGGGTTCCCTATGTAAGCTGTACTTCCGGGAACTCCCAAACCCTCTGCTTACCTAC
CAGCTGTATGAGAAATTTTCTGATGCAGTTTCAGCAGCAACAGATGAAGAAAGGCTGATAAAAATCCACGATGTCATCCAGCAGCTCCCC
CCACCACACTACAGAACACTGGAGTTCCTGATGAGACACTTGTCTCTTCTAGCTGACTATTGTTCCATCACAAATATGCATGCAAAAAAT
CTAGCAATTGTTTGGGCTCCAAACCTGTTAAGATCAAAACAGATAGAATCTGCCTGCTTCAGTGGAACAGCAGCTTTCATGGAAGTGAGG
ATTCAGTCTGTGGTTGTTGAGTTCATCCTGAATCACGTTGATGTGCTGTTCAGCGGCAGAATCAGCATGGCCATGCAAGAGGGGGCAGCT
TCTCTATCAAGGCCCAAGTCCCTCCTGGTATCCTCTCCATCCACCAAACTGCTGACATTGGAAGAGGCCCAGGCACGAACACAAGCTCAG
GTCAATTCTCCAATTGTGACGGAAAATAAATATATCGAAGTAGGAGAAGGACCTGCTGCACTTCAGGGGAAATTTCATACCATAATTGAG
TTCCCACTTGAAAGAAAGAGGCCTCAAAATAAGATGAAAAAGTCTCCTGTGGGTAGCTGGCGTTCCTTTTTCAACTTGGGGAAATCATCA
TCTGTTTCTAAACGAAAGCTGCAGCGGAATGAGAGTGAGCCTTCAGAGATGAAAGCCATGGCTCTGAAAGGTGGCAGGGCAGAAGGAACC
CTCCGTTCAGCTAAAAGTGAGGAGTCTCTTACATCTCTCCATGCAGTTGATGGTGATTCTAAGCTCTTCCGACCCAGAAGACCCAGATCT
TCCAGTGATGCACTGTCTGCCTCTTTTAATGGAGAAATGCTGGGGAACCGCTGTAACTCCTATGATAATCTGCCTCATGACAATGAGAGT
GAGGAGGAAGGAGGGCTGCTTCATATCCCAGCCCTTATGTCTCCTCATTCAGCTGAGGATGTTGACTTGAGCCCACCAGACATTGGAGTA
GCCAGCCTGGATTTTGATCCAATGTCATTTCAATGTAGTCCTCCTAAGGCCGAATCAGAATGTCTGGAGAGTGGTGCTTCCTTTTTAGAT
TCACCAGGATACTCCAAGGATAAACCAAGTGCCAATAAAAAGGATGCAGAAACAGGTAGTAGCCAATGTCAGACTCCAGGAAGCACAGCA
AGCTCTGAACCTGTCTCTCCTCTTCAGGAGAAACTGAGTCCATTCTTTACCCTGGACTTGAGCCCAACTGAAGATAAATCATCTAAGCCA
TCCTCCTTTACTGAAAAGGTCGTCTATGCTTTCTCTCCGAAGATAGGACGGAAATTAAGCAAATCACCTTCTATGAGCATATCTGAGCCA
ATTTCAGTGACCCTACCACCACGGGTGTCAGAAGTCATTGGTACAGTCTCAAATACCACAGCTCAGAATGCATCATCTTCAACCTGGGAC
AAATGCGTTGAAGAAAGGGATGCCACAAATAGATCCCCCACCCAGATAGTAAAGATGAAAACAAATGAGACAGTTGCCCAAGAAGCATAT
GAATCTGAAGTCCAGCCCCTGGACCAGGTGGCTGCTGAAGAAGTAGAATTGCCAGGGAAAGAGGATCAGTCTGTCTCAAGCAGTCAGAGT
AAGGCTGTAGCTTCTGGACAGACTCAGACAGGAGCAGTTACCCATGACCCCCCTCAGGATTCCGTTCCTGTCAGTTCAGTCTCTCTTATC
CCACCACCACCGCCTCCGAAAAATGTTGCCCGAATGTTGGCGCTAGCATTAGCTGAGTCCGCACAGCAAGCCTCAACTCAGTCATTGAAG
AGACCAGGGACCTCTCAGGCTGGGTATACAAATTATGGAGACATAGCGGTGGCTACAACTGAAGATAATCTGTCCAGTTCTTACTCTGCA
GTTGCTCTAGATAAGGCCTATTTCCAAACCGATCGACCAGCAGAGCAGTTCCACCTCCAGAATAATGCACCAGGAAACTGTGACCATCCT
CTACCAGAGACAACAGCTACTGGGGATCCTACCCATTCCAACACAACTGAATCTGGGGAGCAACATCACCAAGTAGACTTAACAGGGAAT
CAGCCACATCAAGCATATTTATCTGGGGACCCAGAAAAGGCCAGAATTACTTCAGTTCCCTTAGACTCAGAGAAGTCTGATGATCATGTA
AGTTTCCCTGAAGACCAGTCTGGGAAGAACAGTATGCCAACTGTCTCCTTCTTGGATCAGGACCAGTCTCCACCCCGTTTCTACAGTGGA
GATCAGCCTCCTTCTTATCTTGGTGCAAGTGTGGATAAACTCCATCACCCTTTAGAATTTGCAGACAAATCTCCCACACCTCCTAATTTA
CCTAGCGATAAAATCTACCCTCCTTCTGGGTCCCCCGAAGAGAATACCAGCACAGCCACCATGACTTACATGACAACTACTCCAGCAACA
GCCCAAATGAGCACCAAGGAAGCCAGCTGGGATGTGGCTGAACAACCCACCACTGCTGATTTTGCTGCTGCCACACTTCAGCGCACGCAC
AGAACTAATCGTCCCCTTCCCCCTCCGCCTTCCCAGAGATCTGCAGAGCAGCCACCAGTTGTGGGGCAGGTACAAGCAGCAACCAATATA
GGATTAAATAATTCCCACAAGGTTCAAGGAGTAGTTCCAGTTCCAGAGAGGCCACCTGAACCTCGAGCCATGGATGACCCTGCGTCTGCC
TTCATCAGTGACAGTGGTGCTGCTGCTGCTCAGTGTCCCATGGCTACAGCTGTCCAGCCAGGCCTGCCTGAGAAAGTGCGGGACGGTGCC
CGGGTCCCGCTGCTGCACCTGCGCGCCGAGTCTGTCCCTGCGCATCCCTGTGGCTTTCCTGCACCACTGCCCCCCACCAGGATGATGGAG
AGTAAGATGATTGCTGCCATACACTCCAGCAGTGCAGATGCCACCAGCAGTTCAAATTATCATTCCTTTGTCACTGCTTCATCCACCTCT
GTGGACGATGCATTGCCTTTACCACTTCCTGTCCCACAACCTAAGCATGCTTCTCAGAAAACAGTTTACTCCTCCTTTGCTAGGCCCGAT
GTCACCACTGAACCCTTTGGTCCAGATAACTGTTTGCATTTCAATATGACTCCAAACTGCCAGTACCGTCCCCAGAGTGTACCTCCCCAT
CACAATAAATTGGAGCAGCACCAAGTGTATGGTGCCAGGTCAGAGCCACCAGCCTCCATGGGTCTTCGTTATAACACATATGTGGCCCCA
GGAAGAAACGCATCTGGACACCACTCCAAGCCATGCAGCCGGGTCGAGTATGTGTCTTCTTTGAGCTCCTCTGTCAGGAATACCTGTTAC
CCCGAAGACATTCCACCGTACCCTACCATCCGGAGAGTGCAGTCTCTCCATGCTCCGCCGTCTTCCATGATTCGCTCTGTTCCCATTTCA
CGGACAGAAGTTCCCCCAGATGATGAGCCAGCCTACTGCCCAAGACCTCTGTACCAATATAAGCCATATCAGTCCTCCCAGGCCCGCTCA
GATTATCATGTCACTCAGCTTCAGCCTTACTTTGAGAATGGCCGGGTCCACTACAGGTATAGCCCATATTCCAGTTCTTCTAGTTCCTAT
TACAGTCCAGATGGGGCCCTGTGTGATGTGGATGCCTATGGCACAGTCCAGTTGAGACCCCTTCACCGCCTTCCCAATCGAGACTTTGCT
TTCTACAATCCTAGGCTGCAAGGAAAGAGCTTGTACAGTTATGCTGGTTTGGCTCCACGTCCCCGGGCCAACGTGACTGGCTATTTCTCT
CCCAACGACCATAATGTAGTCAGCATGCCTCCGGCTGCTGATGTGAAGCACACCTACACCTCATGGGATCTTGAGGACATGGAAAAATAC
CGCATGCAGTCCATCCGGAGAGAGAGCCGTGCTCGGCAGAAGGTGAAAGGGCCTGTCATGTCCCAATATGATAACATGACCCCGGCGGTG
CAGGACGACTTGGGTGGGATCTATGTCATCCATCTGCGTAGTAAATCAGATCCTGGGAAAACTGGACTTCTCTCAGTGGCAGAAGGAAAG
GAGAGCCGCCATGCAGCCAAGGCCATCAGTCCCGAGGGAGAGGACCGCTTCTATAGGAGGCATCCCGAGGCAGAGATGGACAGAGCCCAC
CATCACGGAGGCCATGGTAGCACGCAGCCGGAGAAGCCATCCCTGCCTCAGAAGCAGAGCAGCCTGAGGAGCAGGAAGCTTCCTGACATG
GGCTGCAGTCTTCCTGAGCACAGGGCACACCAAGAAGCAAGCCATAGGCAGTTCTGTGAGTCAAAGAATGGGCCCCCTTATCCCCAGGGA
GCTGGCCAGTTAGATTATGGGTCCAAAGGGATTCCAGACACTTCTGAGCCAGTCAGCTACCACAACTCTGGAGTAAAATATGCTGCATCC
GGGCAAGAATCTTTAAGACTGAACCACAAAGAGGTAAGGCTCTCCAAAGAGATGGAGCGACCCTGGGTTAGGCAGCCTTCTGCCCCAGAG
AAACACTCCAGAGACTGCTACAAGGAGGAAGAACACCTCACTCAGTCAATCGTCCCACCCCCTAAACCAGAGAGGAGTCATAGCCTCAAA
CTCCATCATACCCAGAACGTGGAGAGGGACCCCAGTGTGCTGTACCAGTACCAACCACACGGCAAGCGCCAGAGCAGTGTGACTGTTGTG
TCCCAGTATGATAACCTGGAAGATTACCACTCCCTGCCTCAGCACCAGCGAGGAGTCTTTGGAGGGGGCGGCATGGGGACGTATGTGCCC
CCTGGCTTTCCCCATCCACAGAGCAGGACCTATGCTACAGCGTTGGGTCAAGGGGCCTTCCTGCCCGCAGAGTTGTCCTTGCAGCATCCT
GAAACACAGATCCATGCAGAATGAGCCCTGCGAGCAATAGAGTTGAAGCAGCCTCTGCTGGACAGTGGACTGTTCTATTTTTTTCAATAA
CCAAAAAGATTAAACAAAAAATACTATAAAACCCCTGACCACATTTAAAAAATGATAATAAAAGTAAACAAATCAGCATCTTTTTCCCCT
TCCCTGCTTCATTACCCCCTCTTCCATCTATAGACTTTGTCATTTTTGTCTTTAGAAAAGATCTGAAGGATGGTAAAGCCCCGTGCTGAA
ACCCAGTAGAGAAACCTGTCTCAGGACACACTTGCCATCTAGGGCTAGCTTGAAAGAGCCTGAGGACTGCCTTTAACTGAATTTGAATTC
AGCATTGTCCTTTCTTCTTAGTATTTGCTGCATAATTGAGAGCAGTTCACATCGATTTCCTGGTAGGCGTCTGCATTCCCTGTTGTGTTC
CTGCTTCTCCTTCAGTAGCTGCACAACTTGCGCAGATCGACACACTGTTGTCACTTCATTCTCCCCGTCTGAGAAGGATCTTGTGTTCAG
TTAGAGTCGTGGAAAAATCCCTGATCCTTCAAGGTCAGTCAGACAGTTGGCAACATTATAATTAAAAATAAGAAATTAAGACTTTAAATT
AAACATTTGGTAGAGTCATCATAAAACACCAGACCACTTAGACTCAGGCTGAACCATACTCTTTCTATTCTTATTTTTCATCCTTGTTCC
TCACGGTTCAGTGAACAGGCTCATATCATGACAGAATGGACTTTTAAAAGTTAGTACTTAAGGAAACTTCTTTAGGTGGAAGAAAGTAAA
GTTCTTATTGTCAGTGAACTTTATTAGCACCAGAAATCTCTATTGATGCTTTTAATGCATTGCCTGCCTTCAGGTTTTCTTCTTACCCCA
CCCCTCAATAAGATTTGGTGAATTGTAATTCTAGTAAAACATGTCATACCATTGGTTTTCCTAAATTATCAACTTTCTTTCATTAAAAAA
AAAAAAAAAAAAAAAAGCCCAGCATGGTTTGACTGGATAGACACGCATAATTTATTATGAATATAAATTTCCATGTTTGTTTCTGTTCCT
AAACCAGAGTACGAGGTCCCTGGGAATTTAAGTAGCTACGCATTATCTATTATTAGACTGCAAGTTCCTGCAATAACTGCTTAGTTCACA
GCCCCGTTTCACCAGTGGAGTTCTGGGCAGTTATTGCTGTCCTAAGGCATTACTGTCGTTTGCTTACTCTATACTTGTGTGGTCACAGTC
TTCTTGTAATTACCATCTACACCAGCATTTCAGGTATAGCTCTTTATAACTCTGGAGACATGTAAAACATGTTTAACACCCACGAGTTTT
GAAAGTTGCATTCCTTATTAGAGTAGGAACTCTCTAGCCCAACTCCATTCTATGTTCTCAGCTCCCTCCACCCCCCAAAATACATCAGAC
TAGCAAGGCAGTCCTATGTTTACAAAACGAGTTTAGATTGTCATTTCATTCCATAACTCTTAATAATACTCAAGTTTTATACATTCACGT
ATTTTAAATGCTCGGTCTGTAGAAGACACTAGGAGAATTGCATTCCAATTACTGGATGGTTGCTGCTCTGGCTTTTTAGAACTTGAAATT
AATTTTTATTTAGAGCAAAGGAGGAAATCTTTTAAGAGGCTAAAATCATGCTGCTATTATTGCTGTGAAATTGTATAAAGATTAGGATTC
ATGCCAGTTTTTATTTTAAAAAATAATGTGCATTTTAAGGGTTTATATTTAGAAAAAAATAAAATGTTTCAAGAACAACACATTGATATG
TGGAAATATTCTATAAGGTTTTCTTTTGTTCCCTTAGAATTCATTGGAGGGATGCAGTAAAAACTGTAGTAGAAACCTTGAAACACCCAT
ATGTGAAAAGGTCTGTGGAAATTGAGGCCTCTACATTAAAAGTGCAGAACCAACTGTTTTACAGTCAAAGTGCTAGGAAACCTGATAGGA
TACTTCCCTTTGGCACAAAAACACCCTGGGTGCTACATACAGGAGTATGACCTTTGGTGAATATGTGGCACTAATTTTTTTTACCTTAAT
CATATTCTTGTCAAGTAGGCAACCCATTGCCCCTTGGAGACCACACCAGCCCTGTAAGTTCTCACCAGCAGCATGGAGATTAGGAAGAGG
GGCTGCTGTGACCAGGAGATACACACGGCTTTAAGTAACTGAGAGCCTAAAGAAAGTAACCCAGGGAGTCCGGTCCAGTTTTAATATTTG
TGGATTTGTTGTCACACACATTGTTTAGTCCTGAAACTAAAACCTATTTTATAAATAGTAGGGTTAATTCCTCGAAACAATTTCTTTATT
AATAAATGTCCTGTGGGTTTAGAAATATCAGGTAAATATTTGAATACAGAATGATGATTGCAATTACTGTTACAAGCGTGAAACACAAAC
TTCAGATCAAATCTAGAGTTGCTTCATTTAATGCATGCTAGCAACAGCCTTAACTTTGGATTCAGTTATTTGAAACACTTTTCCGGCATC
TTTCCCTTTCTAATGTTGTGGGGTGGAAACCGGATGGCAAATCACTGTGAGCCGGATACCTCAGCACAGTCCACCTTGTGTGTGACTTCA
CAAATGGGGGACTTCACAAATGGGGTAACTGAATGTTATTACTTTCAAATTTTGACATGGAGCATTATGATCAAGGAAATGGAGCTGCCT
TATACATTAAACCCGTGATTTAATCCTATTGACATTTTCATAGCCATGCCTCCAGATTTTATCTTTTTGGCAAAATTCTGATTCCACAGT
TTGGTCTGATTGAAATAAATATTCCCTGGACGTCTGGCTAAAAATTTTGCTAACAATCCCAGAGGTGCCATTTTCTTATTAATAAATTTC
ATTGGAGCCTTATTTCTTACTATATTCAATTTCGTTTCAAACCTGCAAGTCCCTGGGATGGTCCCACGACTAGGGCCTGCACATTTCTTA
CAATGGCAAAGCATTTTTTAAAATTTAGGGTCAGGTTGAAAAATTCTAGGACTAATTCTGTAGAGAGGAGGGACTGTTAACTAACGTGAG
TGGGGACGGAGGAGTAGGTTACCACATTTGGAGCAGTAATAGATGCAAACGATGTAAATTTGAAATTTGCCCCTTTAGTTAAAGAAGGAG
CCTGCAAAGTCCATTTCTCTGTTTTCAGCCCTGTCAGTCACCCATTTAGGATGTTGGCAAAGTACTGCTTGAGCAGAATGTGTAAGAAAG
TAATAATGAAAGCAAAAGTATGTCAGACAGTTACTTCTTCCACATGGTTAGAGGCATGTGATTTTCAGCACTGTGTGTTACAGAAATGTC
AGGAATGGTGTATTATAACGTGTGCAAGATAATGTCAGTGTGCACAGAGGGTCTTTTTTCCTTATCTGATTAGTACTGTTAATGTTCAAA
GAATAAAAATGGTTTTACAGTTTAGATTCTGAGATAGCAAAACCTGATTTTTCAACCATGACCTGCATGAGAGAAGCATCCTAGGAAGTC
TTAGATCATACTTTTGAGTTTTTAATTTTAATTTATATAGTGTTTTTTTATGTCTTAATATTTTTGTGAACTGGTGTAAATTGTTAATGC
ATATAAGCTTGTGTATTTTTGTAAATAGTTTTGTGATTTATTTCTTGCCCCATATGTAAATATTTAGAGTCTCATTTCTTGCAAACTTAT
TTGAAGCTGAGTTGTGGGTTTGGGTTTTGTTTGTTTCTTTGGTTGCAGGGTGGGGTGGGGGGTGGCAGGGGAGGGAGGAAGGGATTTTTG
TACCTGGAGATGGAGATATCTTGTGGTTTAAAGCAAATGTCCCACTGAAAGTGATTCAAATATCAACAGAATTATTTCAGGTTAAAACAG

>67383_67383_3_PPFIA1-ARHGAP32_PPFIA1_chr11_70118542_ENST00000389547_ARHGAP32_chr11_128963602_ENST00000310343_length(amino acids)=2091AA_BP=138
MGRRAPGPRRGAGRRTPAAGCFRRLPSSPGASSRPRAAAEPPRPLPPASKMMCEVMPTISEAEGPPGGGGGHGSGSPSQPDADSHFEQLM
VSMLEERDRLLDTLRETQETLALTQGKLHEVGHERDSLQRQLNTALPQLSLSEEQNEVMKNGCESKELVYLVQIACQGKSWIVKRSYEDF
RVLDKHLHLCIYDRRFSQLSELPRSDTLKDSPESVTQMLMAYLSRLSAIAGNKINCGPALTWMEIDNKGNHLLVHEESSINTPAVGAAHV
IKRYTARAPDELTLEVGDIVSVIDMPPKVLSTWWRGKHGFQVGLFPGHCVELINQKVPQSVTNSVPKPVSKKHGKLITFLRTFMKSRPTK
QKLKQRGILKERVFGCDLGEHLLNSGFEVPQVLQSCTAFIERYGIVDGIYRLSGVASNIQRLRHEFDSEHVPDLTKEPYVQDIHSVGSLC
KLYFRELPNPLLTYQLYEKFSDAVSAATDEERLIKIHDVIQQLPPPHYRTLEFLMRHLSLLADYCSITNMHAKNLAIVWAPNLLRSKQIE
SACFSGTAAFMEVRIQSVVVEFILNHVDVLFSGRISMAMQEGAASLSRPKSLLVSSPSTKLLTLEEAQARTQAQVNSPIVTENKYIEVGE
GPAALQGKFHTIIEFPLERKRPQNKMKKSPVGSWRSFFNLGKSSSVSKRKLQRNESEPSEMKAMALKGGRAEGTLRSAKSEESLTSLHAV
DGDSKLFRPRRPRSSSDALSASFNGEMLGNRCNSYDNLPHDNESEEEGGLLHIPALMSPHSAEDVDLSPPDIGVASLDFDPMSFQCSPPK
AESECLESGASFLDSPGYSKDKPSANKKDAETGSSQCQTPGSTASSEPVSPLQEKLSPFFTLDLSPTEDKSSKPSSFTEKVVYAFSPKIG
RKLSKSPSMSISEPISVTLPPRVSEVIGTVSNTTAQNASSSTWDKCVEERDATNRSPTQIVKMKTNETVAQEAYESEVQPLDQVAAEEVE
LPGKEDQSVSSSQSKAVASGQTQTGAVTHDPPQDSVPVSSVSLIPPPPPPKNVARMLALALAESAQQASTQSLKRPGTSQAGYTNYGDIA
VATTEDNLSSSYSAVALDKAYFQTDRPAEQFHLQNNAPGNCDHPLPETTATGDPTHSNTTESGEQHHQVDLTGNQPHQAYLSGDPEKARI
TSVPLDSEKSDDHVSFPEDQSGKNSMPTVSFLDQDQSPPRFYSGDQPPSYLGASVDKLHHPLEFADKSPTPPNLPSDKIYPPSGSPEENT
STATMTYMTTTPATAQMSTKEASWDVAEQPTTADFAAATLQRTHRTNRPLPPPPSQRSAEQPPVVGQVQAATNIGLNNSHKVQGVVPVPE
RPPEPRAMDDPASAFISDSGAAAAQCPMATAVQPGLPEKVRDGARVPLLHLRAESVPAHPCGFPAPLPPTRMMESKMIAAIHSSSADATS
SSNYHSFVTASSTSVDDALPLPLPVPQPKHASQKTVYSSFARPDVTTEPFGPDNCLHFNMTPNCQYRPQSVPPHHNKLEQHQVYGARSEP
PASMGLRYNTYVAPGRNASGHHSKPCSRVEYVSSLSSSVRNTCYPEDIPPYPTIRRVQSLHAPPSSMIRSVPISRTEVPPDDEPAYCPRP
LYQYKPYQSSQARSDYHVTQLQPYFENGRVHYRYSPYSSSSSSYYSPDGALCDVDAYGTVQLRPLHRLPNRDFAFYNPRLQGKSLYSYAG
LAPRPRANVTGYFSPNDHNVVSMPPAADVKHTYTSWDLEDMEKYRMQSIRRESRARQKVKGPVMSQYDNMTPAVQDDLGGIYVIHLRSKS
DPGKTGLLSVAEGKESRHAAKAISPEGEDRFYRRHPEAEMDRAHHHGGHGSTQPEKPSLPQKQSSLRSRKLPDMGCSLPEHRAHQEASHR
QFCESKNGPPYPQGAGQLDYGSKGIPDTSEPVSYHNSGVKYAASGQESLRLNHKEVRLSKEMERPWVRQPSAPEKHSRDCYKEEEHLTQS
IVPPPKPERSHSLKLHHTQNVERDPSVLYQYQPHGKRQSSVTVVSQYDNLEDYHSLPQHQRGVFGGGGMGTYVPPGFPHPQSRTYATALG

--------------------------------------------------------------
>67383_67383_4_PPFIA1-ARHGAP32_PPFIA1_chr11_70118542_ENST00000389547_ARHGAP32_chr11_128963602_ENST00000524655_length(transcript)=8452nt_BP=462nt
GCTCCTCCTCCGCTCCGCCAGTGTCCGGCCGCGGGCCGGCCTTAGTGACTGGGGCGGCGGGCCCCGGGGCCGCGGCGTGGGGCGGGCAGG
CGGACGCCGGCCGCGGGCTGCTTTCGTCGGCTCCCAAGCTCTCCCGGAGCGAGCAGCCGCCCGCGAGCCGCCGCGGAGCCTCCTCGCCCG
CTCCCGCCGGCGAGCAAGATGATGTGCGAGGTGATGCCGACCATCAGCGAAGCAGAAGGCCCCCCTGGAGGAGGTGGAGGCCATGGTTCC
GGCTCCCCTTCACAGCCAGATGCAGATTCACATTTTGAACAGTTGATGGTCTCCATGCTAGAAGAAAGGGACCGCCTTCTTGATACACTG
AGAGAGACTCAAGAAACGCTGGCCTTAACCCAGGGGAAGTTACACGAGGTTGGTCATGAAAGAGATTCCTTGCAGAGACAGCTCAACACG
GCACTTCCACAGCTTTCACTTTCAGAAGAACAGAATGAAGTAATGAAAAATGGCTGTGAATCTAAAGAGCTGGTCTACCTCGTGCAGATT
GCTTGTCAGGGAAAAAGTTGGATTGTTAAAAGAAGTTATGAAGATTTTCGGGTACTTGATAAACATCTTCATCTGTGTATTTATGACCGA
AGATTTTCCCAGCTCTCAGAACTTCCCCGTTCTGACACCCTGAAGGACAGTCCAGAGTCGGTCACTCAGATGCTTATGGCTTACCTGTCA
CGCCTTTCAGCTATCGCTGGCAACAAGATCAACTGTGGGCCCGCCCTTACCTGGATGGAGATTGATAATAAGGGAAATCACCTTTTGGTT
CATGAGGAGTCATCCATCAACACTCCTGCTGTCGGTGCTGCCCATGTTATCAAGAGGTACACTGCTCGGGCCCCTGACGAACTGACCTTA
GAGGTGGGAGACATTGTTTCTGTTATTGACATGCCCCCGAAAGTGTTAAGCACATGGTGGAGAGGCAAGCACGGATTCCAGGTGGGACTC
TTCCCTGGACACTGTGTTGAGTTAATTAACCAAAAAGTTCCCCAGTCAGTGACCAACTCAGTGCCAAAACCAGTGTCTAAAAAGCACGGC
AAGCTCATTACGTTCTTACGAACATTCATGAAGTCTCGTCCAACAAAACAGAAGCTGAAGCAGCGGGGAATCTTGAAAGAGAGGGTGTTT
GGTTGTGACCTGGGGGAACACCTTCTAAATTCTGGTTTTGAAGTGCCGCAGGTTCTTCAAAGCTGCACAGCATTCATTGAGAGATATGGC
ATCGTGGATGGAATCTATCGCCTTTCTGGTGTTGCCTCCAATATCCAGAGACTACGCCATGAATTTGACTCTGAGCACGTCCCCGACCTG
ACGAAAGAACCGTATGTTCAGGACATCCATTCTGTGGGTTCCCTATGTAAGCTGTACTTCCGGGAACTCCCAAACCCTCTGCTTACCTAC
CAGCTGTATGAGAAATTTTCTGATGCAGTTTCAGCAGCAACAGATGAAGAAAGGCTGATAAAAATCCACGATGTCATCCAGCAGCTCCCC
CCACCACACTACAGAACACTGGAGTTCCTGATGAGACACTTGTCTCTTCTAGCTGACTATTGTTCCATCACAAATATGCATGCAAAAAAT
CTAGCAATTGTTTGGGCTCCAAACCTGTTAAGATCAAAACAGATAGAATCTGCCTGCTTCAGTGGAACAGCAGCTTTCATGGAAGTGAGG
ATTCAGTCTGTGGTTGTTGAGTTCATCCTGAATCACGTTGATGTGCTGTTCAGCGGCAGAATCAGCATGGCCATGCAAGAGGGGGCAGCT
TCTCTATCAAGGCCCAAGTCCCTCCTGGTATCCTCTCCATCCACCAAACTGCTGACATTGGAAGAGGCCCAGGCACGAACACAAGCTCAG
GTCAATTCTCCAATTGTGACGGAAAATAAATATATCGAAGTAGGAGAAGGACCTGCTGCACTTCAGGGGAAATTTCATACCATAATTGAG
TTCCCACTTGAAAGAAAGAGGCCTCAAAATAAGATGAAAAAGTCTCCTGTGGGTAGCTGGCGTTCCTTTTTCAACTTGGGGAAATCATCA
TCTGTTTCTAAACGAAAGCTGCAGCGGAATGAGAGTGAGCCTTCAGAGATGAAAGCCATGGCTCTGAAAGGTGGCAGGGCAGAAGGAACC
CTCCGTTCAGCTAAAAGTGAGGAGTCTCTTACATCTCTCCATGCAGTTGATGGTGATTCTAAGCTCTTCCGACCCAGAAGACCCAGATCT
TCCAGTGATGCACTGTCTGCCTCTTTTAATGGAGAAATGCTGGGGAACCGCTGTAACTCCTATGATAATCTGCCTCATGACAATGAGAGT
GAGGAGGAAGGAGGGCTGCTTCATATCCCAGCCCTTATGTCTCCTCATTCAGCTGAGGATGTTGACTTGAGCCCACCAGACATTGGAGTA
GCCAGCCTGGATTTTGATCCAATGTCATTTCAATGTAGTCCTCCTAAGGCCGAATCAGAATGTCTGGAGAGTGGTGCTTCCTTTTTAGAT
TCACCAGGATACTCCAAGGATAAACCAAGTGCCAATAAAAAGGATGCAGAAACAGGTAGTAGCCAATGTCAGACTCCAGGAAGCACAGCA
AGCTCTGAACCTGTCTCTCCTCTTCAGGAGAAACTGAGTCCATTCTTTACCCTGGACTTGAGCCCAACTGAAGATAAATCATCTAAGCCA
TCCTCCTTTACTGAAAAGGTCGTCTATGCTTTCTCTCCGAAGATAGGACGGAAATTAAGCAAATCACCTTCTATGAGCATATCTGAGCCA
ATTTCAGTGACCCTACCACCACGGGTGTCAGAAGTCATTGGTACAGTCTCAAATACCACAGCTCAGAATGCATCATCTTCAACCTGGGAC
AAATGCGTTGAAGAAAGGGATGCCACAAATAGATCCCCCACCCAGATAGTAAAGATGAAAACAAATGAGACAGTTGCCCAAGAAGCATAT
GAATCTGAAGTCCAGCCCCTGGACCAGGTGGCTGCTGAAGAAGTAGAATTGCCAGGGAAAGAGGATCAGTCTGTCTCAAGCAGTCAGAGT
AAGGCTGTAGCTTCTGGACAGACTCAGACAGGTACCGTTTGTTTTCCTCCATTCTTTCTTTAAGTTAAGAGGGATCTTCAATCCTGTGTG
CCATCTGTGCCTTTTAAGAGAGAAATTTGTCCACAGCTAGCCTTTAATCAAAGAGAATGCTTTTCTGGGTGGTGCTGATGGCTCAGAGCC
CTAAATTAAAAGCAGTCCAACAAAACTCCCCAAAAGGGCCAATGGTCCTGCTTCAAATCTTCACAAAAGTCCCCTTATCTCTTTGGACGG
TGAGAATTCGTGGATAATTTTTGCACAACTGCGTAGCTCTTGATTCTGTTTTTCTCTTCTAATAAAATATCTTTATTGTAGCCTTCCAAG
TTAACAAGCCAGCTACACCATCAAATGTAAAAACTGTTCATAATAACAGTCTACAAGCACTTGAAGCTTGTTTTCTAAGCAATCTTTTCT
GAGCCAGGTGAGGGACATGCTTTTTTTCCCCCCCATCTCTGTAACAATTCAAGAAGAGATTGCAGTCTTTATACACTGTTTGTTTTAGTT
TTCCTTCTGAACCAGATGTGTTTTCAACAGCATTTGCATGTGGGATAGAAGATCATGGATTGCCATTTTGAAATATGGAAGGCACCTATT
TTTTAATGATCACATGGGGAGTGTTTGGCTTTCCATTTAGGATAACGTAAGCTACCTTTTCACTCTCATTTTTTTTCCCAATTTCCCACT
AGGAGCAGTTACCCATGACCCCCCTCAGGATTCCGTTCCTGTCAGTTCAGTCTCTCTTATCCCACCACCACCGCCTCCGAAAAATGTTGC
CCGAATGTTGGCGCTAGCATTAGCTGAGTCCGCACAGCAAGCCTCAACTCAGTCATTGAAGAGACCAGGGACCTCTCAGGCTGGGTATAC
AAATTATGGAGACATAGCGGTGGCTACAACTGAAGATAATCTGTCCAGTTCTTACTCTGCAGTTGCTCTAGATAAGGCCTATTTCCAAAC
CGATCGACCAGCAGAGCAGTTCCACCTCCAGAATAATGCACCAGGAAACTGTGACCATCCTCTACCAGAGACAACAGCTACTGGGGATCC
TACCCATTCCAACACAACTGAATCTGGGGAGCAACATCACCAAGTAGACTTAACAGGGAATCAGCCACATCAAGCATATTTATCTGGGGA
CCCAGAAAAGGCCAGAATTACTTCAGTTCCCTTAGACTCAGAGAAGTCTGATGATCATGTAAGTTTCCCTGAAGACCAGTCTGGGAAGAA
CAGTATGCCAACTGTCTCCTTCTTGGATCAGGACCAGTCTCCACCCCGTTTCTACAGTGGAGATCAGCCTCCTTCTTATCTTGGTGCAAG
TGTGGATAAACTCCATCACCCTTTAGAATTTGCAGACAAATCTCCCACACCTCCTAATTTACCTAGCGATAAAATCTACCCTCCTTCTGG
GTCCCCCGAAGAGAATACCAGCACAGCCACCATGACTTACATGACAACTACTCCAGCAACAGCCCAAATGAGCACCAAGGAAGCCAGCTG
GGATGTGGCTGAACAACCCACCACTGCTGATTTTGCTGCTGCCACACTTCAGCGCACGCACAGAACTAATCGTCCCCTTCCCCCTCCGCC
TTCCCAGAGATCTGCAGAGCAGCCACCAGTTGTGGGGCAGGTACAAGCAGCAACCAATATAGGATTAAATAATTCCCACAAGGTAAGAAG
GGGAAGATATCAGTGAGATGAAATATACTATTACCAAAGGTATGTCACTTTTCAGCAGGGTGTGTTGTTATCTTTGAGTCAGACACAACA
ATTACTTTTAAGCCCTGTGGCTGGTTTCCATGAGATAGTTCCCATTTGAGGTTGGAGTCTGCCATTACCTTGATGCTGGCTTTTCCCCAG
GAAAGGAGTAGCTCCTAGATGACTATAGCTTAACTGTACCTGCTCCCTTTTCTTCCTAAAGTGTCTCGGTAGTTTATTCCAGTAACACAA
AGAGATCAGGATCAAATGAGACAAAGTGGGCTTTACGGTTGTGGGTTGCTTTTTCTTATTTTTTTCCAACTCCATCACTGACTCATTGTG
ACTTTGGGCAAGTCATTTACCTACCCTCTGCCAATTATTCACAGTTACACAATGAAAATACTTCATTCTCAAAACATTCGTAAGACTGTC
TGCCTTGCAGACTTTTTGGAAGTATAAGAGATTATAGTGCCTTGGGATTTTTTGTTACTTTCCTAGCATTCACCAGCAGTTTGTCCCATA
GTCAGGTGCCTGTTTCAATGAGAGAATGTAGTATGCAGAATGCTAAGGTTTCTTCCTGAATTTCCTCATATTTTAAGAAAGTGCCACAGG
TTGTTTTTCTTCTATATGGTCACCTTGAACTATTAATAGGACTTAAGATTTTAGACCTTAGTGGAGGATGCTGTGTTTACTGCTTCTCAA
GGATAGCATGTTTTCAGTATGAGGATTATCTTTGGCCAGACTAAGGTGGAATCAAAGGTAGGAGAGAGGCAGTAGCTTCTGATTTGAATA
TTGCCTTTCCCTATGTTTGAAGCCCTAAAACTGCTAACTGTGTACAACTGTGAATTTCAAAAGTCTCCCCAGATGATAGAATTAACTCTT
AATTTAACAAGATGTCCTTTGTGTTGAGACTGAGCTAGACTAATAGACCGGGTATGTATTTTTAAGCTCTACAGCATTACTTGACTAAAC
CTCTCTTTTGGTTTGTATATTAAAATTATGCCATAGGCAACCTCATCTCGCATTTAAAACCTCTCATAAATTAGAAAACTTTGAATGGTT
CTCCAAAGATAATACTGGGTGTTGTACAAAATAGCAGCACAAGCCTTCTTTTCCTAGAAATGGGTACAGATTCATTGCAACCACATGGCT
TGGGAAAGTTCAAGCTGCTACCCAACCAGCCTTAATTTGTGAGTTACAAATTTAATAGTACTTGATTCATAGAGGGAACAAAAAATAGAC
CCATAGTATTATCATCTTTCAATAGGTTCAAGGAGTAGTTCCAGTTCCAGAGAGGCCACCTGAACCTCGAGCCATGGATGACCCTGCGTC
TGCCTTCATCAGTGACAGTGGTGCTGCTGCTGCTCAGTGTCCCATGGCTACAGCTGTCCAGCCAGGCCTGCCTGAGAAAGTGCGGGACGG
TGCCCGGGTCCCGCTGCTGCACCTGCGCGCCGAGTCTGTCCCTGCGCATCCCTGTGGCTTTCCTGCACCACTGCCCCCCACCAGGATGAT
GGAGAGTAAGATGATTGCTGCCATACACTCCAGCAGTGCAGATGCCACCAGCAGTTCAAATTATCATTCCTTTGTCACTGCTTCATCCAC
CTCTGTGGACGATGCATTGCCTTTACCACTTCCTGTCCCACAACCTAAGCATGCTTCTCAGAAAACAGTTTACTCCTCCTTTGCTAGGCC
CGATGTCACCACTGAACCCTTTGGTCCAGATAACTGTTTGCATTTCAATATGACTCCAAACTGCCAGTACCGTCCCCAGAGTGTACCTCC
CCATCACAATAAATTGGAGCAGCACCAAGTGTATGGTGCCAGGTCAGAGCCACCAGCCTCCATGGGTCTTCGTTATAACACATATGTGGC
CCCAGGAAGAAACGCATCTGGACACCACTCCAAGCCATGCAGCCGGGTCGAGTATGTGTCTTCTTTGAGCTCCTCTGTCAGGAATACCTG
TTACCCCGAAGACATTCCACCGTACCCTACCATCCGGAGAGTGCAGTCTCTCCATGCTCCGCCGTCTTCCATGATTCGCTCTGTTCCCAT
TTCACGGACAGAAGTTCCCCCAGATGATGAGCCAGCCTACTGCCCAAGACCTCTGTACCAATATAAGCCATATCAGTCCTCCCAGGCCCG
CTCAGATTATCATGTCACTCAGCTTCAGCCTTACTTTGAGAATGGCCGGGTCCACTACAGGTATAGCCCATATTCCAGTTCTTCTAGTTC
CTATTACAGTCCAGATGGGGCCCTGTGTGATGTGGATGCCTATGGCACAGTCCAGTTGAGACCCCTTCACCGCCTTCCCAATCGAGACTT
TGCTTTCTACAATCCTAGGCTGCAAGGAAAGAGCTTGTACAGTTATGCTGGTTTGGCTCCACGTCCCCGGGCCAACGTGACTGGCTATTT
CTCTCCCAACGACCATAATGTAGTCAGCATGCCTCCGGCTGCTGATGTGAAGCACACCTACACCTCATGGGATCTTGAGGACATGGAAAA
ATACCGCATGCAGTCCATCCGGAGAGAGAGCCGTGCTCGGCAGAAGGTGAAAGGGCCTGTCATGTCCCAATATGATAACATGACCCCGGC
GGTGCAGGACGACTTGGGTGGGATCTATGTCATCCATCTGCGTAGTAAATCAGATCCTGGGAAAACTGGACTTCTCTCAGTGGCAGAAGG
AAAGGAGAGCCGCCATGCAGCCAAGGCCATCAGTCCCGAGGGAGAGGACCGCTTCTATAGGAGGCATCCCGAGGCAGAGATGGACAGAGC
CCACCATCACGGAGGCCATGGTAGCACGCAGCCGGAGAAGCCATCCCTGCCTCAGAAGCAGAGCAGCCTGAGGAGCAGGAAGCTTCCTGA
CATGGGCTGCAGTCTTCCTGAGCACAGGGCACACCAAGAAGCAAGCCATAGGCAGTTCTGTGAGTCAAAGAATGGGCCCCCTTATCCCCA
GGGAGCTGGCCAGTTAGATTATGGGTCCAAAGGGATTCCAGACACTTCTGAGCCAGTCAGCTACCACAACTCTGGAGTAAAATATGCTGC
ATCCGGGCAAGAATCTTTAAGACTGAACCACAAAGAGGTAAGGCTCTCCAAAGAGATGGAGCGACCCTGGGTTAGGCAGCCTTCTGCCCC
AGAGAAACACTCCAGAGACTGCTACAAGGAGGAAGAACACCTCACTCAGTCAATCGTCCCACCCCCTAAACCAGAGAGGAGTCATAGCCT
CAAACTCCATCATACCCAGAACGTGGAGAGGGACCCCAGTGTGCTGTACCAGTACCAACCACACGGCAAGCGCCAGAGCAGTGTGACTGT
TGTGTCCCAGTATGATAACCTGGAAGATTACCACTCCCTGCCTCAGCACCAGCGAGGAGTCTTTGGAGGGGGCGGCATGGGGACGTATGT
GCCCCCTGGCTTTCCCCATCCACAGAGCAGGACCTATGCTACAGCGTTGGGTCAAGGGGCCTTCCTGCCCGCAGAGTTGTCCTTGCAGCA
TCCTGAAACACAGATCCATGCAGAATGAGCCCTGCGAGCAATAGAGTTGAAGCAGCCTCTGCTGGACAGTGGACTGTTCTATTTTTTTCA

>67383_67383_4_PPFIA1-ARHGAP32_PPFIA1_chr11_70118542_ENST00000389547_ARHGAP32_chr11_128963602_ENST00000524655_length(amino acids)=1024AA_BP=138
MGRRAPGPRRGAGRRTPAAGCFRRLPSSPGASSRPRAAAEPPRPLPPASKMMCEVMPTISEAEGPPGGGGGHGSGSPSQPDADSHFEQLM
VSMLEERDRLLDTLRETQETLALTQGKLHEVGHERDSLQRQLNTALPQLSLSEEQNEVMKNGCESKELVYLVQIACQGKSWIVKRSYEDF
RVLDKHLHLCIYDRRFSQLSELPRSDTLKDSPESVTQMLMAYLSRLSAIAGNKINCGPALTWMEIDNKGNHLLVHEESSINTPAVGAAHV
IKRYTARAPDELTLEVGDIVSVIDMPPKVLSTWWRGKHGFQVGLFPGHCVELINQKVPQSVTNSVPKPVSKKHGKLITFLRTFMKSRPTK
QKLKQRGILKERVFGCDLGEHLLNSGFEVPQVLQSCTAFIERYGIVDGIYRLSGVASNIQRLRHEFDSEHVPDLTKEPYVQDIHSVGSLC
KLYFRELPNPLLTYQLYEKFSDAVSAATDEERLIKIHDVIQQLPPPHYRTLEFLMRHLSLLADYCSITNMHAKNLAIVWAPNLLRSKQIE
SACFSGTAAFMEVRIQSVVVEFILNHVDVLFSGRISMAMQEGAASLSRPKSLLVSSPSTKLLTLEEAQARTQAQVNSPIVTENKYIEVGE
GPAALQGKFHTIIEFPLERKRPQNKMKKSPVGSWRSFFNLGKSSSVSKRKLQRNESEPSEMKAMALKGGRAEGTLRSAKSEESLTSLHAV
DGDSKLFRPRRPRSSSDALSASFNGEMLGNRCNSYDNLPHDNESEEEGGLLHIPALMSPHSAEDVDLSPPDIGVASLDFDPMSFQCSPPK
AESECLESGASFLDSPGYSKDKPSANKKDAETGSSQCQTPGSTASSEPVSPLQEKLSPFFTLDLSPTEDKSSKPSSFTEKVVYAFSPKIG
RKLSKSPSMSISEPISVTLPPRVSEVIGTVSNTTAQNASSSTWDKCVEERDATNRSPTQIVKMKTNETVAQEAYESEVQPLDQVAAEEVE

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Fusion Gene PPI Analysis for PPFIA1-ARHGAP32


check button Go to ChiPPI (Chimeric Protein-Protein interactions) to see the chimeric PPI interaction in

ChiPPI page.


check button Protein-protein interactors with each fusion partner protein in wild-type (BIOGRID-3.4.160)
HgeneHgene's interactorsTgeneTgene's interactors


check button - Retained PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenStill interaction with
TgeneARHGAP32chr11:70118542chr11:128963602ENST000003103433221685_2087134.02088.0FYN
TgeneARHGAP32chr11:70118542chr11:128963602ENST000003926570131685_208701739.0FYN
TgeneARHGAP32chr11:70118542chr11:128963602ENST000005272720121685_208701739.0FYN
TgeneARHGAP32chr11:70118542chr11:128963602ENST000003103433221391_1711134.02088.0GAB2
TgeneARHGAP32chr11:70118542chr11:128963602ENST000003926570131391_171101739.0GAB2
TgeneARHGAP32chr11:70118542chr11:128963602ENST000005272720121391_171101739.0GAB2


check button - Lost PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


check button - Retained PPIs, but lost function due to frame-shift fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


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Related Drugs for PPFIA1-ARHGAP32


check button Drugs targeting genes involved in this fusion gene.
(DrugBank Version 5.1.8 2021-05-08)
PartnerGeneUniProtAccDrugBank IDDrug nameDrug activityDrug typeDrug status

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Related Diseases for PPFIA1-ARHGAP32


check button Diseases associated with fusion partners.
(DisGeNet 4.0)
PartnerGeneDisease IDDisease name# pubmedsSource