FusionGDB Logo

Home

Download

Statistics

Examples

Help

Contact
Center for Computational Systems Medicine
leaf

Fusion Gene Summary

leaf

Fusion Gene ORF analysis

leaf

Fusion Genomic Features

leaf

Fusion Protein Features

leaf

Fusion Gene Sequence

leaf

Fusion Gene PPI analysis

leaf

Related Drugs

leaf

Related Diseases

Fusion gene:PPFIBP1-RSL1D1 (FusionGDB2 ID:67462)

Fusion Gene Summary for PPFIBP1-RSL1D1

check button Fusion gene summary
Fusion gene informationFusion gene name: PPFIBP1-RSL1D1
Fusion gene ID: 67462
HgeneTgene
Gene symbol

PPFIBP1

RSL1D1

Gene ID

8496

26156

Gene namePPFIA binding protein 1ribosomal L1 domain containing 1
SynonymsL2|SGT2|hSGT2|hSgt2pCSIG|L12|PBK1|UTP30
Cytomap

12p11.23-p11.22

16p13.13

Type of geneprotein-codingprotein-coding
Descriptionliprin-beta-1PTPRF interacting protein, binding protein 1 (liprin beta 1)PTPRF-interacting protein-binding protein 1liprin related proteinprotein-tyrosine phosphatase receptor-type f polypeptide-interacting protein-binding protein 1ribosomal L1 domain-containing protein 1CATX-11cellular senescence-inhibited gene protein
Modification date2020031320200313
UniProtAcc..
Ensembl transtripts involved in fusion geneENST00000228425, ENST00000318304, 
ENST00000537927, ENST00000542629, 
ENST00000535047, ENST00000541633, 
ENST00000545334, 		ENST00000542106, 
ENST00000571133, 
Fusion gene scores* DoF score20 X 14 X 13=36407 X 9 X 4=252
# samples 2610
** MAII scorelog2(26/3640*10)=-3.8073549220576
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0		log2(10/252*10)=-1.33342373372519
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0
Context

PubMed: PPFIBP1 [Title/Abstract] AND RSL1D1 [Title/Abstract] AND fusion [Title/Abstract]

Most frequent breakpointPPFIBP1(27820253)-RSL1D1(11933842), # samples:1
Anticipated loss of major functional domain due to fusion event.
* DoF score (Degree of Frequency) = # partners X # break points X # cancer types
** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10)

check button Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez
PartnerGeneGO IDGO termPubMed ID
TgeneRSL1D1

GO:0042981

regulation of apoptotic process

18678645

TgeneRSL1D1

GO:2000772

regulation of cellular senescence

18678645


check buttonFusion gene breakpoints across PPFIBP1 (5'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.
all structure

check buttonFusion gene breakpoints across RSL1D1 (3'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.
all structure

check button Fusion gene information from two resources (ChiTars 5.0 and ChimerDB 4.0)
* All genome coordinats were lifted-over on hg19.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
SourceDiseaseSampleHgeneHchrHbpHstrandTgeneTchrTbpTstrand
ChimerDB4Non-CancerERR315407PPFIBP1chr12

27820253

+RSL1D1chr16

11933842

-


Top

Fusion Gene ORF analysis for PPFIBP1-RSL1D1

check button Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
ORFHenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrand
In-frameENST00000228425ENST00000542106PPFIBP1chr12

27820253

+RSL1D1chr16

11933842

-
In-frameENST00000228425ENST00000571133PPFIBP1chr12

27820253

+RSL1D1chr16

11933842

-
In-frameENST00000318304ENST00000542106PPFIBP1chr12

27820253

+RSL1D1chr16

11933842

-
In-frameENST00000318304ENST00000571133PPFIBP1chr12

27820253

+RSL1D1chr16

11933842

-
In-frameENST00000537927ENST00000542106PPFIBP1chr12

27820253

+RSL1D1chr16

11933842

-
In-frameENST00000537927ENST00000571133PPFIBP1chr12

27820253

+RSL1D1chr16

11933842

-
In-frameENST00000542629ENST00000542106PPFIBP1chr12

27820253

+RSL1D1chr16

11933842

-
In-frameENST00000542629ENST00000571133PPFIBP1chr12

27820253

+RSL1D1chr16

11933842

-
intron-3CDSENST00000535047ENST00000542106PPFIBP1chr12

27820253

+RSL1D1chr16

11933842

-
intron-3CDSENST00000535047ENST00000571133PPFIBP1chr12

27820253

+RSL1D1chr16

11933842

-
intron-3CDSENST00000541633ENST00000542106PPFIBP1chr12

27820253

+RSL1D1chr16

11933842

-
intron-3CDSENST00000541633ENST00000571133PPFIBP1chr12

27820253

+RSL1D1chr16

11933842

-
intron-3CDSENST00000545334ENST00000542106PPFIBP1chr12

27820253

+RSL1D1chr16

11933842

-
intron-3CDSENST00000545334ENST00000571133PPFIBP1chr12

27820253

+RSL1D1chr16

11933842

-

check buttonORFfinder result based on the fusion transcript sequence of in-frame fusion genes.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandSeq length
(transcript)		BP loci
(transcript)		Predicted start
(transcript)		Predicted stop
(transcript)		Seq length
(amino acids)
ENST00000537927PPFIBP1chr1227820253+ENST00000571133RSL1D1chr1611933842-440511992571816519
ENST00000537927PPFIBP1chr1227820253+ENST00000542106RSL1D1chr1611933842-188611992571816519
ENST00000318304PPFIBP1chr1227820253+ENST00000571133RSL1D1chr1611933842-468614802502097615
ENST00000318304PPFIBP1chr1227820253+ENST00000542106RSL1D1chr1611933842-216714802502097615
ENST00000542629PPFIBP1chr1227820253+ENST00000571133RSL1D1chr1611933842-457513692321986584
ENST00000542629PPFIBP1chr1227820253+ENST00000542106RSL1D1chr1611933842-205613692321986584
ENST00000228425PPFIBP1chr1227820253+ENST00000571133RSL1D1chr1611933842-458513792001996598
ENST00000228425PPFIBP1chr1227820253+ENST00000542106RSL1D1chr1611933842-206613792001996598

check buttonDeepORF prediction of the coding potential based on the fusion transcript sequence of in-frame fusion genes. DeepORF is a coding potential classifier based on convolutional neural network by comparing the real Ribo-seq data. If the no-coding score < 0.5 and coding score > 0.5, then the in-frame fusion transcript is predicted as being likely translated.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandNo-coding scoreCoding score
ENST00000537927ENST00000571133PPFIBP1chr1227820253+RSL1D1chr1611933842-0.0012924180.99870753
ENST00000537927ENST00000542106PPFIBP1chr1227820253+RSL1D1chr1611933842-0.005916170.9940838
ENST00000318304ENST00000571133PPFIBP1chr1227820253+RSL1D1chr1611933842-0.001881280.9981187
ENST00000318304ENST00000542106PPFIBP1chr1227820253+RSL1D1chr1611933842-0.0070162690.9929837
ENST00000542629ENST00000571133PPFIBP1chr1227820253+RSL1D1chr1611933842-0.002215180.9977848
ENST00000542629ENST00000542106PPFIBP1chr1227820253+RSL1D1chr1611933842-0.0073115980.9926884
ENST00000228425ENST00000571133PPFIBP1chr1227820253+RSL1D1chr1611933842-0.0016938230.99830616
ENST00000228425ENST00000542106PPFIBP1chr1227820253+RSL1D1chr1611933842-0.0056259180.99437404

Top

Fusion Genomic Features for PPFIBP1-RSL1D1


check buttonFusionAI prediction of the potential fusion gene breakpoint based on the pre-mature RNA sequence context (+/- 5kb of individual partner genes, total 20kb length sequence). FusionAI is a fusion gene breakpoint classifier based on convolutional neural network by comparing the fusion positive and negative sequence context of ~ 20K fusion gene data. From here, we can have the relative potentency of the 20K genomic sequence how individual sequnce will be likely used as the gene fusion breakpoints.
HgeneHchrHbpHstrandTgeneTchrTbpTstrand1-pp (fusion gene breakpoint)

check buttonDistribution of 44 human genomic features loci across 20kb length fusion breakpoint regions. We integrated a total of 44 different types of human genomic feature loci information across five big categories including virus integration sites, repeats, structural variants, chromatin states, and gene expression regulation. More details are in help page.
genomic feature

check buttonDistribution of 44 human genomic features loci across 20kb length fusion breakpoint regions that are ovelapped with the top 1% feature importance score regions. More details are in help page.

Top

Fusion Protein Features for PPFIBP1-RSL1D1


check button Four levels of functional features of fusion genes
Go to FGviewer search page for the most frequent breakpoint (https://ccsmweb.uth.edu/FGviewer/chr12:27820253/chr16:11933842)
- FGviewer provides the online visualization of the retention search of the protein functional features across DNA, RNA, protein, and pathological levels.
- How to search
1. Put your fusion gene symbol.
2. Press the tab key until there will be shown the breakpoint information filled.
4. Go down and press 'Search' tab twice.
4. Go down to have the hyperlink of the search result.
5. Click the hyperlink.
6. See the FGviewer result for your fusion gene.
FGviewer

check buttonMain function of each fusion partner protein. (from UniProt)
HgeneTgene
..
FUNCTION: Transcriptional activator which is required for calcium-dependent dendritic growth and branching in cortical neurons. Recruits CREB-binding protein (CREBBP) to nuclear bodies. Component of the CREST-BRG1 complex, a multiprotein complex that regulates promoter activation by orchestrating a calcium-dependent release of a repressor complex and a recruitment of an activator complex. In resting neurons, transcription of the c-FOS promoter is inhibited by BRG1-dependent recruitment of a phospho-RB1-HDAC1 repressor complex. Upon calcium influx, RB1 is dephosphorylated by calcineurin, which leads to release of the repressor complex. At the same time, there is increased recruitment of CREBBP to the promoter by a CREST-dependent mechanism, which leads to transcriptional activation. The CREST-BRG1 complex also binds to the NR2B promoter, and activity-dependent induction of NR2B expression involves a release of HDAC1 and recruitment of CREBBP (By similarity). {ECO:0000250}.FUNCTION: Transcriptional activator which is required for calcium-dependent dendritic growth and branching in cortical neurons. Recruits CREB-binding protein (CREBBP) to nuclear bodies. Component of the CREST-BRG1 complex, a multiprotein complex that regulates promoter activation by orchestrating a calcium-dependent release of a repressor complex and a recruitment of an activator complex. In resting neurons, transcription of the c-FOS promoter is inhibited by BRG1-dependent recruitment of a phospho-RB1-HDAC1 repressor complex. Upon calcium influx, RB1 is dephosphorylated by calcineurin, which leads to release of the repressor complex. At the same time, there is increased recruitment of CREBBP to the promoter by a CREST-dependent mechanism, which leads to transcriptional activation. The CREST-BRG1 complex also binds to the NR2B promoter, and activity-dependent induction of NR2B expression involves a release of HDAC1 and recruitment of CREBBP (By similarity). {ECO:0000250}.

check buttonRetention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at

download page


* Minus value of BPloci means that the break pointn is located before the CDS.
- In-frame and retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note

- In-frame and not-retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
HgenePPFIBP1chr12:27820253chr16:11933842ENST00000228425+1330156_4053821006.0Coiled coilOntology_term=ECO:0000255
HgenePPFIBP1chr12:27820253chr16:11933842ENST00000318304+1329156_4053991012.0Coiled coilOntology_term=ECO:0000255
HgenePPFIBP1chr12:27820253chr16:11933842ENST00000535047+16156_4050171.0Coiled coilOntology_term=ECO:0000255
HgenePPFIBP1chr12:27820253chr16:11933842ENST00000537927+1127156_405246859.0Coiled coilOntology_term=ECO:0000255
HgenePPFIBP1chr12:27820253chr16:11933842ENST00000542629+1228156_405368981.0Coiled coilOntology_term=ECO:0000255
HgenePPFIBP1chr12:27820253chr16:11933842ENST00000228425+1330647_7113821006.0DomainSAM 1
HgenePPFIBP1chr12:27820253chr16:11933842ENST00000228425+1330719_7823821006.0DomainSAM 2
HgenePPFIBP1chr12:27820253chr16:11933842ENST00000228425+1330804_8763821006.0DomainSAM 3
HgenePPFIBP1chr12:27820253chr16:11933842ENST00000318304+1329647_7113991012.0DomainSAM 1
HgenePPFIBP1chr12:27820253chr16:11933842ENST00000318304+1329719_7823991012.0DomainSAM 2
HgenePPFIBP1chr12:27820253chr16:11933842ENST00000318304+1329804_8763991012.0DomainSAM 3
HgenePPFIBP1chr12:27820253chr16:11933842ENST00000535047+16647_7110171.0DomainSAM 1
HgenePPFIBP1chr12:27820253chr16:11933842ENST00000535047+16719_7820171.0DomainSAM 2
HgenePPFIBP1chr12:27820253chr16:11933842ENST00000535047+16804_8760171.0DomainSAM 3
HgenePPFIBP1chr12:27820253chr16:11933842ENST00000537927+1127647_711246859.0DomainSAM 1
HgenePPFIBP1chr12:27820253chr16:11933842ENST00000537927+1127719_782246859.0DomainSAM 2
HgenePPFIBP1chr12:27820253chr16:11933842ENST00000537927+1127804_876246859.0DomainSAM 3
HgenePPFIBP1chr12:27820253chr16:11933842ENST00000542629+1228647_711368981.0DomainSAM 1
HgenePPFIBP1chr12:27820253chr16:11933842ENST00000542629+1228719_782368981.0DomainSAM 2
HgenePPFIBP1chr12:27820253chr16:11933842ENST00000542629+1228804_876368981.0DomainSAM 3
TgeneRSL1D1chr12:27820253chr16:11933842ENST0000057113369280_313285491.0Coiled coilOntology_term=ECO:0000255


Top

Fusion Gene Sequence for PPFIBP1-RSL1D1


check button For in-frame fusion transcripts, we provide the fusion transcript sequences and fusion amino acid sequences. To have fusion amino acid sequence, we ran ORFfinder and chose the longest ORF among the all predicted ones.
>67462_67462_1_PPFIBP1-RSL1D1_PPFIBP1_chr12_27820253_ENST00000228425_RSL1D1_chr16_11933842_ENST00000542106_length(transcript)=2066nt_BP=1379nt
GACTCGTGTGCTGCGAGCTGGCGGCCGGGCCGGAGTGCTGGGGCTTTGAACTCCGAGAGGAGGTGGACCAGAACTTTTGGAACTAGTGCC
GGCGGCTCTCCACCCCCCAGTATAAAAGAACGTGTGGATCACTTTGCTGAGTACATCCAAGATTTGAAGAACTGAAATAAATCAGCTTTA
AACCTGCTTTTTAAAAATATCTGGGTTGGAATTTGCCCCTGACAAATAATAAAATGATGAGTGATGCAAGTGACATGTTGGCTGCAGCGT
TGGAGCAGATGGATGGTATCATAGCAGGTTCTAAGGCTCTGGAATATTCCAATGGGATTTTTGATTGCCAATCTCCCACCTCTCCATTCA
TGGGAAGTTTGCGAGCTCTGCACCTTGTGGAAGACCTGCGTGGATTGTTAGAGATGATGGAAACAGATGAGAAAGAAGGCTTGAGATGCC
AGATCCCAGATTCAACAGCAGAAACGCTTGTTGAATGGCTTCAGAGTCAAATGACAAATGGACACCTACCAGGGAACGGAGATGTGTATC
AAGAAAGGCTGGCACGTTTAGAAAATGATAAAGAATCCCTCGTTCTTCAGGTAAGTGTGTTAACAGACCAGGTGGAGGCTCAGGGAGAGA
AGATTCGAGATTTGGAGTTTTGTCTTGAAGAGCACAGAGAGAAGGTGAATGCCACAGAAGAAATGCTGCAGCAGGAGCTTCTAAGTAGGA
CATCCTTAGAAACTCAGAAGTTGGATCTGATGGCTGAAATATCTAACTTGAAGTTGAAACTGACAGCTGTAGAGAAGGACAGATTGGATT
ATGAAGATAAGTTCAGAGACACAGAGGGGCTGATTCAGGAGATCAATGATTTGAGGTTAAAAGTTAGTGAAATGGACAGTGAGAGACTTC
AGTATGAAAAAAAGCTTAAATCAACCAAAGATGAACTGGCATCTTTAAAAGAACAACTAGAAGAAAAGGAATCTGAAGTAAAAAGGCTAC
AAGAAAAATTGGTTTGCAAGATGAAAGGAGAAGGGGTTGAAATTGTTGATAGAGATGAAAATTTTAAAAAGAAGCTCAAAGAAAAAAACA
TCGAAGTACAAAAAATGAAAAAAGCTGTGGAGTCCTTGATGGCAGCAAATGAAGAAAAGGATCGGAAAATAGAAGATCTTCGACAGTGCC
TGAACAGGTACAAGAAAATGCAAGACACGGTGGTACTGGCCCAAGGTAAAAAAGGCAAAGATGGAGAATATGAAGAGCTGCTCAATTCCA
GTTCCATCTCCTCTTTGCTGGATGCACAGGGTTTCAGTGATCTGGAGAAAAGTCCATCACCCACTCCAGTAATGGGATCTCCCAGTTGTG
ACCCATTTAACACAAGTGTTCCCGAAGAGGAGGCAAGGAGAAAACGAAGAGAAAGAAATTTTGAAAAACAAAAGGAGAGGAAGAAGAAGA
GGCAGCAGGCTAGGAAGACTGCATCAGTTCTTAGTAAAGATGATGTGGCACCTGAAAGTGGTGATACTACAGTGAAGAAACCTGAATCAA
AGAAGGAACAGACCCCAGAGCATGGGAAGAAAAAACGTGGCAGAGGAAAAGCCCAAGTTAAAGCAACAAATGAATCCGAAGACGAAATCC
CACAGCTGGTACCAATAGGAAAGAAGACTCCAGCTAATGAAAAAGTAGAGATTCAAAAACATGCCACAGGAAAGAAGTCTCCAGCAAAGA
GTCCTAATCCCAGCACACCTCGTGGGAAGAAAAGAAAGGCTTTGCCAGCATCTGAGACCCCAAAAGCTGCAGAGTCTGAGACCCCAGGGA
AAAGCCCAGAGAAGAAGCCAAAAATCAAAGAAGAGGCAGTGAAGGAAAAAAGTCCTTCGCTGGGGAAAAAAGATGCGAGACAGACTCCAA
AAAAGCCAGAGGCCAAGTTTTTCACCACTCCTAGTAAATCTGTGAGAAAAGCTTCCCACACCCCCAAAAAATGGCCCAAAAAACCCAAAG

>67462_67462_1_PPFIBP1-RSL1D1_PPFIBP1_chr12_27820253_ENST00000228425_RSL1D1_chr16_11933842_ENST00000542106_length(amino acids)=598AA_BP=393
MGWNLPLTNNKMMSDASDMLAAALEQMDGIIAGSKALEYSNGIFDCQSPTSPFMGSLRALHLVEDLRGLLEMMETDEKEGLRCQIPDSTA
ETLVEWLQSQMTNGHLPGNGDVYQERLARLENDKESLVLQVSVLTDQVEAQGEKIRDLEFCLEEHREKVNATEEMLQQELLSRTSLETQK
LDLMAEISNLKLKLTAVEKDRLDYEDKFRDTEGLIQEINDLRLKVSEMDSERLQYEKKLKSTKDELASLKEQLEEKESEVKRLQEKLVCK
MKGEGVEIVDRDENFKKKLKEKNIEVQKMKKAVESLMAANEEKDRKIEDLRQCLNRYKKMQDTVVLAQGKKGKDGEYEELLNSSSISSLL
DAQGFSDLEKSPSPTPVMGSPSCDPFNTSVPEEEARRKRRERNFEKQKERKKKRQQARKTASVLSKDDVAPESGDTTVKKPESKKEQTPE
HGKKKRGRGKAQVKATNESEDEIPQLVPIGKKTPANEKVEIQKHATGKKSPAKSPNPSTPRGKKRKALPASETPKAAESETPGKSPEKKP

--------------------------------------------------------------
>67462_67462_2_PPFIBP1-RSL1D1_PPFIBP1_chr12_27820253_ENST00000228425_RSL1D1_chr16_11933842_ENST00000571133_length(transcript)=4585nt_BP=1379nt
GACTCGTGTGCTGCGAGCTGGCGGCCGGGCCGGAGTGCTGGGGCTTTGAACTCCGAGAGGAGGTGGACCAGAACTTTTGGAACTAGTGCC
GGCGGCTCTCCACCCCCCAGTATAAAAGAACGTGTGGATCACTTTGCTGAGTACATCCAAGATTTGAAGAACTGAAATAAATCAGCTTTA
AACCTGCTTTTTAAAAATATCTGGGTTGGAATTTGCCCCTGACAAATAATAAAATGATGAGTGATGCAAGTGACATGTTGGCTGCAGCGT
TGGAGCAGATGGATGGTATCATAGCAGGTTCTAAGGCTCTGGAATATTCCAATGGGATTTTTGATTGCCAATCTCCCACCTCTCCATTCA
TGGGAAGTTTGCGAGCTCTGCACCTTGTGGAAGACCTGCGTGGATTGTTAGAGATGATGGAAACAGATGAGAAAGAAGGCTTGAGATGCC
AGATCCCAGATTCAACAGCAGAAACGCTTGTTGAATGGCTTCAGAGTCAAATGACAAATGGACACCTACCAGGGAACGGAGATGTGTATC
AAGAAAGGCTGGCACGTTTAGAAAATGATAAAGAATCCCTCGTTCTTCAGGTAAGTGTGTTAACAGACCAGGTGGAGGCTCAGGGAGAGA
AGATTCGAGATTTGGAGTTTTGTCTTGAAGAGCACAGAGAGAAGGTGAATGCCACAGAAGAAATGCTGCAGCAGGAGCTTCTAAGTAGGA
CATCCTTAGAAACTCAGAAGTTGGATCTGATGGCTGAAATATCTAACTTGAAGTTGAAACTGACAGCTGTAGAGAAGGACAGATTGGATT
ATGAAGATAAGTTCAGAGACACAGAGGGGCTGATTCAGGAGATCAATGATTTGAGGTTAAAAGTTAGTGAAATGGACAGTGAGAGACTTC
AGTATGAAAAAAAGCTTAAATCAACCAAAGATGAACTGGCATCTTTAAAAGAACAACTAGAAGAAAAGGAATCTGAAGTAAAAAGGCTAC
AAGAAAAATTGGTTTGCAAGATGAAAGGAGAAGGGGTTGAAATTGTTGATAGAGATGAAAATTTTAAAAAGAAGCTCAAAGAAAAAAACA
TCGAAGTACAAAAAATGAAAAAAGCTGTGGAGTCCTTGATGGCAGCAAATGAAGAAAAGGATCGGAAAATAGAAGATCTTCGACAGTGCC
TGAACAGGTACAAGAAAATGCAAGACACGGTGGTACTGGCCCAAGGTAAAAAAGGCAAAGATGGAGAATATGAAGAGCTGCTCAATTCCA
GTTCCATCTCCTCTTTGCTGGATGCACAGGGTTTCAGTGATCTGGAGAAAAGTCCATCACCCACTCCAGTAATGGGATCTCCCAGTTGTG
ACCCATTTAACACAAGTGTTCCCGAAGAGGAGGCAAGGAGAAAACGAAGAGAAAGAAATTTTGAAAAACAAAAGGAGAGGAAGAAGAAGA
GGCAGCAGGCTAGGAAGACTGCATCAGTTCTTAGTAAAGATGATGTGGCACCTGAAAGTGGTGATACTACAGTGAAGAAACCTGAATCAA
AGAAGGAACAGACCCCAGAGCATGGGAAGAAAAAACGTGGCAGAGGAAAAGCCCAAGTTAAAGCAACAAATGAATCCGAAGACGAAATCC
CACAGCTGGTACCAATAGGAAAGAAGACTCCAGCTAATGAAAAAGTAGAGATTCAAAAACATGCCACAGGAAAGAAGTCTCCAGCAAAGA
GTCCTAATCCCAGCACACCTCGTGGGAAGAAAAGAAAGGCTTTGCCAGCATCTGAGACCCCAAAAGCTGCAGAGTCTGAGACCCCAGGGA
AAAGCCCAGAGAAGAAGCCAAAAATCAAAGAAGAGGCAGTGAAGGAAAAAAGTCCTTCGCTGGGGAAAAAAGATGCGAGACAGACTCCAA
AAAAGCCAGAGGCCAAGTTTTTCACCACTCCTAGTAAATCTGTGAGAAAAGCTTCCCACACCCCCAAAAAATGGCCCAAAAAACCCAAAG
TACCCCAGTCGACCTAAAGTCAGTGATTCAACTGGAAGGAAACCTCAATGCTGCCTCCAGAGCTTTTTGGAAATACTCAGATCCTGGCCG
CCTTTGTAACCTTCTCTAAACGTCAGGCCTGGACTTAAAAGATTTTTTAAAACCTCCATAAGTAGTCCAGGGGCGGTGGCTCACGCCTGT
AATCCCAGCACTTTGGGAGGCCGAGGCAGGCGGATCACAAGGTCAACGAGATCGAGACCATCCTGGCCAACATGGTGAAACCCTGTCTGT
ACCAAAAATACAAAAATTAATTGGGCATGGTGGTGGACACCTGTAATCCCAGCTACTAGGGAGGCTGAGGCAGGAGAATTGCTTGAACCT
GGGAGGCGGAGGTTGCAGTGAGCCACTGCACTCCAGCCTGATGACAGAGCAAGACTCAGTCTCAAAAATAAATAAAAATAATAAAACCTC
CATAAGTAATCCTGACATATGTTCCTGGGTATAATCTGTTTCTAAATTGTCCTTCTGTGTATTTGCTAATGTAATAGAGGGAAAAATAGA
GTGCTTCTCTGTGGTTGTTCAGCACTTTAGGTAGCCAAGGTGAGAGGATTGCTTGAGGCCAGGAGTTTGAGACTAGCCTGGGCAACTTGG
TAAAACCCCATCTCTACAAAAGAAAAAAAAAAATTAGTGTGGCATGGTGGCATGCATCTGTGCTCCCAGCTCCTCACGAGGCTGAGGTGG
AAGGATCAAGTGAGCGCAAGAGGTTGAGGCTCCAGTGAGCCACGATCACCCCACTGTGCTGTAGCCTGGGTGACAGTGTGAGATTCTGTC
TCAGAAAAAACAAAGTATAACATTGCTTTGCTTCTGAGTATACTGTTGGCTTTCCAAATCAGTGGGTCTGACTTGAGGTCTGTGATGTGA
CCCTTTTCCTCACCTGCTCAACCATTATTCACATGGACTCCATCATATTCATTTGTAGTCATTCCCAGAGTGGCCCAGTGAGGGTCTCGC
TGTATGAGAGTCGGCTACGGAATTTAGGAGAAACAGAAGTTTCTTGGCTTTCATGCTGAGCTTGTTGGTCTAAGCTTATGAGTCACTGGA
TTAGCATCCATATGGGAAGGGAAATTAACATGGAGTCATTTATACAGGGACTAAATTGAATCCTACCTACCGGAGGCAAGAACATGATTT
ATCTTCCATAAGCCTTATCCTCTTCCTCCTTATTCCTCAGTCCATATGGATTTGCTTATGTATGACAACTCCAAGGAATCTTGGAAGAGT
AGATTGCTAACGTTTCCACAATTGTCAAGTATATTCTGAGGCAGTAAACACCTTTTTAGGTACGTGGCCTTTCACTGGTTGTGAATTGGT
ATGCATCCGTAGTAGTAAGTTCACAGATTCACTGCAGTGCAGGAATGTTCTTGCATGCCAAAGACTCAACTGCTTTCAAAGATAATGTGG
GTGCTAGATGCAGTGGCTTACATCTGTAACCCTGTTAGGGTGACCAGACCCAACACCAGGTCGTGGGGGTGACAAAGTCCAGTGGAGTCA
AAGGATTGAGAAAAAGACAGTTTGAGAGAGAAGTAGGACCAGCAGACCATCGGGATGGTGGAGGCTGTGAAGGCCGTGAGCTCTGGGAGC
CCACACTATTTATTGGTAATCCAACAAAGAAACAGATGGTGAGAATGTGAAGGTCAGAAGGGCACCTTGCATTAAGCACATGATTTACAG
CTGTGATGGTTTAGCATTTGCTCTGCTACTTGAGATGATGGAGAGCAGGTTCTTTTAACTCAAGTTACAGTCGATCCTGGGAGAGCAAGG
AGCCAGCAAGTCTAGACATTCCAGAGCCACAGGCCCTGGATTTTATCCAAGCCACGAGGGATTTTATGCCCTGGGCTTAGATTATGGTGC
GTCAGGGCAGCCTTCCACCCTTTAGCACAGAGCTTGGTGTTCCAAAGACCACAAGGGGTTTTAGACCCTTGACCCTGGACATATTCCAAG
ACTCTTTTACATTATGTCAGAATGCAAGCCCTGCCTCAGCTTCTCCCAACACTCAGCTTTTCGCAACATAATCCCAGCACTTTGGAACGC
TGGGTGGATTGCTTGAACCCAGGAGTTCGAGACCATCCTGGGCAATATGGCAAAACCCCATCTTTACCAAAAATAAGCTGGGTGTGGTGG
AACATGCCTGTGGTCCCAGCTTCTTGGGAGGCTGAGGTGGGAGGATTGCTTGAACCCGGGAGGTAGAGGCTGCAATGGGCCATGATCACG
ATCCTGCACTCCAGCCTGGGCAACAGAGAGAGACAGTCCCTGGCCCACTGCCCCCTTCCCTGGCCCAGTCTCAAAAAAAATGAGGCTGGG
CGTGGTGGCTCACATCTGTAATCCCAGCCAAGGCTGGCAGATCACTTGAGGCCAGGAGTTCTGAGACCAGCCTGGCTTACATGGTGAAAC
CCCATCTCTACTAAAAATACAAAAACTAGCCAGGCATGGTGGGAGGCACCTGTAATCCCAGCTACTTGGGAGGCTGAAGCAGGAGAATCA

>67462_67462_2_PPFIBP1-RSL1D1_PPFIBP1_chr12_27820253_ENST00000228425_RSL1D1_chr16_11933842_ENST00000571133_length(amino acids)=598AA_BP=393
MGWNLPLTNNKMMSDASDMLAAALEQMDGIIAGSKALEYSNGIFDCQSPTSPFMGSLRALHLVEDLRGLLEMMETDEKEGLRCQIPDSTA
ETLVEWLQSQMTNGHLPGNGDVYQERLARLENDKESLVLQVSVLTDQVEAQGEKIRDLEFCLEEHREKVNATEEMLQQELLSRTSLETQK
LDLMAEISNLKLKLTAVEKDRLDYEDKFRDTEGLIQEINDLRLKVSEMDSERLQYEKKLKSTKDELASLKEQLEEKESEVKRLQEKLVCK
MKGEGVEIVDRDENFKKKLKEKNIEVQKMKKAVESLMAANEEKDRKIEDLRQCLNRYKKMQDTVVLAQGKKGKDGEYEELLNSSSISSLL
DAQGFSDLEKSPSPTPVMGSPSCDPFNTSVPEEEARRKRRERNFEKQKERKKKRQQARKTASVLSKDDVAPESGDTTVKKPESKKEQTPE
HGKKKRGRGKAQVKATNESEDEIPQLVPIGKKTPANEKVEIQKHATGKKSPAKSPNPSTPRGKKRKALPASETPKAAESETPGKSPEKKP

--------------------------------------------------------------
>67462_67462_3_PPFIBP1-RSL1D1_PPFIBP1_chr12_27820253_ENST00000318304_RSL1D1_chr16_11933842_ENST00000542106_length(transcript)=2167nt_BP=1480nt
GGATTCCTGACATGGTGTAGTGCAGGCAGGGTGGGGAAAGGACGGGGAAGGACTCGTGTGCTGCGAGCTGGCGGCCGGGCCGGAGTGCTG
GGGCTTTGAACTCCGAGAGGAGGTGGACCAGAACTTTTGGAACTAGTGCCGGCGGCTCTCCACCCCCCAGTATAAAAGAACGTGTGGATC
ACTTTGCTGAGTACATCCAAGATTTGAAGAACTGAAATAAATCAGCTTTAAACCTGCTTTTTAAAAATATCTGGGTTGGAATTTGCCCCT
GACAAATAATAAAATGATGAGTGATGCAAGTGACATGTTGGCTGCAGCGTTGGAGCAGATGGATGGTATCATAGCAGGTTCTAAGGCTCT
GGAATATTCCAATGGGATTTTTGATTGCCAATCTCCCACCTCTCCATTCATGGGAAGTTTGCGAGCTCTGCACCTTGTGGAAGACCTGCG
TGGATTGTTAGAGATGATGGAAACAGATGAGAAAGAAGGCTTGAGATGCCAGATCCCAGATTCAACAGCAGAAACGCTTGTTGAATGGCT
TCAGAGTCAAATGACAAATGGACACCTACCAGGGAACGGAGATGTGTATCAAGAAAGGCTGGCACGTTTAGAAAATGATAAAGAATCCCT
CGTTCTTCAGGTAAGTGTGTTAACAGACCAGGTGGAGGCTCAGGGAGAGAAGATTCGAGATTTGGAGTTTTGTCTTGAAGAGCACAGAGA
GAAGGTGAATGCCACAGAAGAAATGCTGCAGCAGGAGCTTCTAAGTAGGACATCCTTAGAAACTCAGAAGTTGGATCTGATGGCTGAAAT
ATCTAACTTGAAGTTGAAACTGACAGCTGTAGAGAAGGACAGATTGGATTATGAAGATAAGTTCAGAGACACAGAGGGGCTGATTCAGGA
GATCAATGATTTGAGGTTAAAAGTTAGTGAAATGGACAGTGAGAGACTTCAGTATGAAAAAAAGCTTAAATCAACCAAATCTTTAATGGC
CAAACTTTCTAGCATGAAAATCAAGGTGGGTCAGATGCAGTATGAAAAGCAGCGGATGGAACAAAAATGGGAGTCACTGAAGGATGAACT
GGCATCTTTAAAAGAACAACTAGAAGAAAAGGAATCTGAAGTAAAAAGGCTACAAGAAAAATTGGTTTGCAAGATGAAAGGAGAAGGGGT
TGAAATTGTTGATAGAGACATCGAAGTACAAAAAATGAAAAAAGCTGTGGAGTCCTTGATGGCAGCAAATGAAGAAAAGGATCGGAAAAT
AGAAGATCTTCGACAGTGCCTGAACAGGTACAAGAAAATGCAAGACACGGTGGTACTGGCCCAAGGCAAAGATGGAGAATATGAAGAGCT
GCTCAATTCCAGTTCCATCTCCTCTTTGCTGGATGCACAGGGTTTCAGTGATCTGGAGAAAAGTCCATCACCCACTCCAGTAATGGGATC
TCCCAGTTGTGACCCATTTAACACAAGTGTTCCCGAAGAGGAGGCAAGGAGAAAACGAAGAGAAAGAAATTTTGAAAAACAAAAGGAGAG
GAAGAAGAAGAGGCAGCAGGCTAGGAAGACTGCATCAGTTCTTAGTAAAGATGATGTGGCACCTGAAAGTGGTGATACTACAGTGAAGAA
ACCTGAATCAAAGAAGGAACAGACCCCAGAGCATGGGAAGAAAAAACGTGGCAGAGGAAAAGCCCAAGTTAAAGCAACAAATGAATCCGA
AGACGAAATCCCACAGCTGGTACCAATAGGAAAGAAGACTCCAGCTAATGAAAAAGTAGAGATTCAAAAACATGCCACAGGAAAGAAGTC
TCCAGCAAAGAGTCCTAATCCCAGCACACCTCGTGGGAAGAAAAGAAAGGCTTTGCCAGCATCTGAGACCCCAAAAGCTGCAGAGTCTGA
GACCCCAGGGAAAAGCCCAGAGAAGAAGCCAAAAATCAAAGAAGAGGCAGTGAAGGAAAAAAGTCCTTCGCTGGGGAAAAAAGATGCGAG
ACAGACTCCAAAAAAGCCAGAGGCCAAGTTTTTCACCACTCCTAGTAAATCTGTGAGAAAAGCTTCCCACACCCCCAAAAAATGGCCCAA
AAAACCCAAAGTACCCCAGTCGACCTAAAGTCAGTGATTCAACTGGAAGGAAACCTCAATGCTGCCTCCAGAGCTTTTTGGAAATACTCA

>67462_67462_3_PPFIBP1-RSL1D1_PPFIBP1_chr12_27820253_ENST00000318304_RSL1D1_chr16_11933842_ENST00000542106_length(amino acids)=615AA_BP=410
MGWNLPLTNNKMMSDASDMLAAALEQMDGIIAGSKALEYSNGIFDCQSPTSPFMGSLRALHLVEDLRGLLEMMETDEKEGLRCQIPDSTA
ETLVEWLQSQMTNGHLPGNGDVYQERLARLENDKESLVLQVSVLTDQVEAQGEKIRDLEFCLEEHREKVNATEEMLQQELLSRTSLETQK
LDLMAEISNLKLKLTAVEKDRLDYEDKFRDTEGLIQEINDLRLKVSEMDSERLQYEKKLKSTKSLMAKLSSMKIKVGQMQYEKQRMEQKW
ESLKDELASLKEQLEEKESEVKRLQEKLVCKMKGEGVEIVDRDIEVQKMKKAVESLMAANEEKDRKIEDLRQCLNRYKKMQDTVVLAQGK
DGEYEELLNSSSISSLLDAQGFSDLEKSPSPTPVMGSPSCDPFNTSVPEEEARRKRRERNFEKQKERKKKRQQARKTASVLSKDDVAPES
GDTTVKKPESKKEQTPEHGKKKRGRGKAQVKATNESEDEIPQLVPIGKKTPANEKVEIQKHATGKKSPAKSPNPSTPRGKKRKALPASET

--------------------------------------------------------------
>67462_67462_4_PPFIBP1-RSL1D1_PPFIBP1_chr12_27820253_ENST00000318304_RSL1D1_chr16_11933842_ENST00000571133_length(transcript)=4686nt_BP=1480nt
GGATTCCTGACATGGTGTAGTGCAGGCAGGGTGGGGAAAGGACGGGGAAGGACTCGTGTGCTGCGAGCTGGCGGCCGGGCCGGAGTGCTG
GGGCTTTGAACTCCGAGAGGAGGTGGACCAGAACTTTTGGAACTAGTGCCGGCGGCTCTCCACCCCCCAGTATAAAAGAACGTGTGGATC
ACTTTGCTGAGTACATCCAAGATTTGAAGAACTGAAATAAATCAGCTTTAAACCTGCTTTTTAAAAATATCTGGGTTGGAATTTGCCCCT
GACAAATAATAAAATGATGAGTGATGCAAGTGACATGTTGGCTGCAGCGTTGGAGCAGATGGATGGTATCATAGCAGGTTCTAAGGCTCT
GGAATATTCCAATGGGATTTTTGATTGCCAATCTCCCACCTCTCCATTCATGGGAAGTTTGCGAGCTCTGCACCTTGTGGAAGACCTGCG
TGGATTGTTAGAGATGATGGAAACAGATGAGAAAGAAGGCTTGAGATGCCAGATCCCAGATTCAACAGCAGAAACGCTTGTTGAATGGCT
TCAGAGTCAAATGACAAATGGACACCTACCAGGGAACGGAGATGTGTATCAAGAAAGGCTGGCACGTTTAGAAAATGATAAAGAATCCCT
CGTTCTTCAGGTAAGTGTGTTAACAGACCAGGTGGAGGCTCAGGGAGAGAAGATTCGAGATTTGGAGTTTTGTCTTGAAGAGCACAGAGA
GAAGGTGAATGCCACAGAAGAAATGCTGCAGCAGGAGCTTCTAAGTAGGACATCCTTAGAAACTCAGAAGTTGGATCTGATGGCTGAAAT
ATCTAACTTGAAGTTGAAACTGACAGCTGTAGAGAAGGACAGATTGGATTATGAAGATAAGTTCAGAGACACAGAGGGGCTGATTCAGGA
GATCAATGATTTGAGGTTAAAAGTTAGTGAAATGGACAGTGAGAGACTTCAGTATGAAAAAAAGCTTAAATCAACCAAATCTTTAATGGC
CAAACTTTCTAGCATGAAAATCAAGGTGGGTCAGATGCAGTATGAAAAGCAGCGGATGGAACAAAAATGGGAGTCACTGAAGGATGAACT
GGCATCTTTAAAAGAACAACTAGAAGAAAAGGAATCTGAAGTAAAAAGGCTACAAGAAAAATTGGTTTGCAAGATGAAAGGAGAAGGGGT
TGAAATTGTTGATAGAGACATCGAAGTACAAAAAATGAAAAAAGCTGTGGAGTCCTTGATGGCAGCAAATGAAGAAAAGGATCGGAAAAT
AGAAGATCTTCGACAGTGCCTGAACAGGTACAAGAAAATGCAAGACACGGTGGTACTGGCCCAAGGCAAAGATGGAGAATATGAAGAGCT
GCTCAATTCCAGTTCCATCTCCTCTTTGCTGGATGCACAGGGTTTCAGTGATCTGGAGAAAAGTCCATCACCCACTCCAGTAATGGGATC
TCCCAGTTGTGACCCATTTAACACAAGTGTTCCCGAAGAGGAGGCAAGGAGAAAACGAAGAGAAAGAAATTTTGAAAAACAAAAGGAGAG
GAAGAAGAAGAGGCAGCAGGCTAGGAAGACTGCATCAGTTCTTAGTAAAGATGATGTGGCACCTGAAAGTGGTGATACTACAGTGAAGAA
ACCTGAATCAAAGAAGGAACAGACCCCAGAGCATGGGAAGAAAAAACGTGGCAGAGGAAAAGCCCAAGTTAAAGCAACAAATGAATCCGA
AGACGAAATCCCACAGCTGGTACCAATAGGAAAGAAGACTCCAGCTAATGAAAAAGTAGAGATTCAAAAACATGCCACAGGAAAGAAGTC
TCCAGCAAAGAGTCCTAATCCCAGCACACCTCGTGGGAAGAAAAGAAAGGCTTTGCCAGCATCTGAGACCCCAAAAGCTGCAGAGTCTGA
GACCCCAGGGAAAAGCCCAGAGAAGAAGCCAAAAATCAAAGAAGAGGCAGTGAAGGAAAAAAGTCCTTCGCTGGGGAAAAAAGATGCGAG
ACAGACTCCAAAAAAGCCAGAGGCCAAGTTTTTCACCACTCCTAGTAAATCTGTGAGAAAAGCTTCCCACACCCCCAAAAAATGGCCCAA
AAAACCCAAAGTACCCCAGTCGACCTAAAGTCAGTGATTCAACTGGAAGGAAACCTCAATGCTGCCTCCAGAGCTTTTTGGAAATACTCA
GATCCTGGCCGCCTTTGTAACCTTCTCTAAACGTCAGGCCTGGACTTAAAAGATTTTTTAAAACCTCCATAAGTAGTCCAGGGGCGGTGG
CTCACGCCTGTAATCCCAGCACTTTGGGAGGCCGAGGCAGGCGGATCACAAGGTCAACGAGATCGAGACCATCCTGGCCAACATGGTGAA
ACCCTGTCTGTACCAAAAATACAAAAATTAATTGGGCATGGTGGTGGACACCTGTAATCCCAGCTACTAGGGAGGCTGAGGCAGGAGAAT
TGCTTGAACCTGGGAGGCGGAGGTTGCAGTGAGCCACTGCACTCCAGCCTGATGACAGAGCAAGACTCAGTCTCAAAAATAAATAAAAAT
AATAAAACCTCCATAAGTAATCCTGACATATGTTCCTGGGTATAATCTGTTTCTAAATTGTCCTTCTGTGTATTTGCTAATGTAATAGAG
GGAAAAATAGAGTGCTTCTCTGTGGTTGTTCAGCACTTTAGGTAGCCAAGGTGAGAGGATTGCTTGAGGCCAGGAGTTTGAGACTAGCCT
GGGCAACTTGGTAAAACCCCATCTCTACAAAAGAAAAAAAAAAATTAGTGTGGCATGGTGGCATGCATCTGTGCTCCCAGCTCCTCACGA
GGCTGAGGTGGAAGGATCAAGTGAGCGCAAGAGGTTGAGGCTCCAGTGAGCCACGATCACCCCACTGTGCTGTAGCCTGGGTGACAGTGT
GAGATTCTGTCTCAGAAAAAACAAAGTATAACATTGCTTTGCTTCTGAGTATACTGTTGGCTTTCCAAATCAGTGGGTCTGACTTGAGGT
CTGTGATGTGACCCTTTTCCTCACCTGCTCAACCATTATTCACATGGACTCCATCATATTCATTTGTAGTCATTCCCAGAGTGGCCCAGT
GAGGGTCTCGCTGTATGAGAGTCGGCTACGGAATTTAGGAGAAACAGAAGTTTCTTGGCTTTCATGCTGAGCTTGTTGGTCTAAGCTTAT
GAGTCACTGGATTAGCATCCATATGGGAAGGGAAATTAACATGGAGTCATTTATACAGGGACTAAATTGAATCCTACCTACCGGAGGCAA
GAACATGATTTATCTTCCATAAGCCTTATCCTCTTCCTCCTTATTCCTCAGTCCATATGGATTTGCTTATGTATGACAACTCCAAGGAAT
CTTGGAAGAGTAGATTGCTAACGTTTCCACAATTGTCAAGTATATTCTGAGGCAGTAAACACCTTTTTAGGTACGTGGCCTTTCACTGGT
TGTGAATTGGTATGCATCCGTAGTAGTAAGTTCACAGATTCACTGCAGTGCAGGAATGTTCTTGCATGCCAAAGACTCAACTGCTTTCAA
AGATAATGTGGGTGCTAGATGCAGTGGCTTACATCTGTAACCCTGTTAGGGTGACCAGACCCAACACCAGGTCGTGGGGGTGACAAAGTC
CAGTGGAGTCAAAGGATTGAGAAAAAGACAGTTTGAGAGAGAAGTAGGACCAGCAGACCATCGGGATGGTGGAGGCTGTGAAGGCCGTGA
GCTCTGGGAGCCCACACTATTTATTGGTAATCCAACAAAGAAACAGATGGTGAGAATGTGAAGGTCAGAAGGGCACCTTGCATTAAGCAC
ATGATTTACAGCTGTGATGGTTTAGCATTTGCTCTGCTACTTGAGATGATGGAGAGCAGGTTCTTTTAACTCAAGTTACAGTCGATCCTG
GGAGAGCAAGGAGCCAGCAAGTCTAGACATTCCAGAGCCACAGGCCCTGGATTTTATCCAAGCCACGAGGGATTTTATGCCCTGGGCTTA
GATTATGGTGCGTCAGGGCAGCCTTCCACCCTTTAGCACAGAGCTTGGTGTTCCAAAGACCACAAGGGGTTTTAGACCCTTGACCCTGGA
CATATTCCAAGACTCTTTTACATTATGTCAGAATGCAAGCCCTGCCTCAGCTTCTCCCAACACTCAGCTTTTCGCAACATAATCCCAGCA
CTTTGGAACGCTGGGTGGATTGCTTGAACCCAGGAGTTCGAGACCATCCTGGGCAATATGGCAAAACCCCATCTTTACCAAAAATAAGCT
GGGTGTGGTGGAACATGCCTGTGGTCCCAGCTTCTTGGGAGGCTGAGGTGGGAGGATTGCTTGAACCCGGGAGGTAGAGGCTGCAATGGG
CCATGATCACGATCCTGCACTCCAGCCTGGGCAACAGAGAGAGACAGTCCCTGGCCCACTGCCCCCTTCCCTGGCCCAGTCTCAAAAAAA
ATGAGGCTGGGCGTGGTGGCTCACATCTGTAATCCCAGCCAAGGCTGGCAGATCACTTGAGGCCAGGAGTTCTGAGACCAGCCTGGCTTA
CATGGTGAAACCCCATCTCTACTAAAAATACAAAAACTAGCCAGGCATGGTGGGAGGCACCTGTAATCCCAGCTACTTGGGAGGCTGAAG
CAGGAGAATCACTTTAACCCGGGAGGTGGAGGTTGCAGTGAGCTGAGATCACACCACTGCACTCCAGCCTGGGCGGCAGAGCAAAACTGA

>67462_67462_4_PPFIBP1-RSL1D1_PPFIBP1_chr12_27820253_ENST00000318304_RSL1D1_chr16_11933842_ENST00000571133_length(amino acids)=615AA_BP=410
MGWNLPLTNNKMMSDASDMLAAALEQMDGIIAGSKALEYSNGIFDCQSPTSPFMGSLRALHLVEDLRGLLEMMETDEKEGLRCQIPDSTA
ETLVEWLQSQMTNGHLPGNGDVYQERLARLENDKESLVLQVSVLTDQVEAQGEKIRDLEFCLEEHREKVNATEEMLQQELLSRTSLETQK
LDLMAEISNLKLKLTAVEKDRLDYEDKFRDTEGLIQEINDLRLKVSEMDSERLQYEKKLKSTKSLMAKLSSMKIKVGQMQYEKQRMEQKW
ESLKDELASLKEQLEEKESEVKRLQEKLVCKMKGEGVEIVDRDIEVQKMKKAVESLMAANEEKDRKIEDLRQCLNRYKKMQDTVVLAQGK
DGEYEELLNSSSISSLLDAQGFSDLEKSPSPTPVMGSPSCDPFNTSVPEEEARRKRRERNFEKQKERKKKRQQARKTASVLSKDDVAPES
GDTTVKKPESKKEQTPEHGKKKRGRGKAQVKATNESEDEIPQLVPIGKKTPANEKVEIQKHATGKKSPAKSPNPSTPRGKKRKALPASET

--------------------------------------------------------------
>67462_67462_5_PPFIBP1-RSL1D1_PPFIBP1_chr12_27820253_ENST00000537927_RSL1D1_chr16_11933842_ENST00000542106_length(transcript)=1886nt_BP=1199nt
CAGCTCCCAGCTCGGTGCCTGCCCGGATTCCTGACATGGTGTAGTGCAGGCAGGGTGGGGAAAGGACGGGGAAGGACTCGTGTGCTGCGA
GCTGGCGGCCGGGCCGGAGTGCTGGGGCTTTGAACTCCGAGAGGAGGTGGACCAGAACTTTTGGAACTAGTGCCGGCGGCTCTCCACCCC
CCAGTATAAAAGAACGTGTGGATCACTTTGCTGAGTACATCCAAGATTTGAAGAACTGAAATAAATCAGCTTTAAACCTGCTTTTTAAAA
ATACAAATGGACACCTACCAGGGAACGGAGATGTGTATCAAGAAAGGCTGGCACGTTTAGAAAATGATAAAGAATCCCTCGTTCTTCAGG
TAAGTGTGTTAACAGACCAGGTGGAGGCTCAGGGAGAGAAGATTCGAGATTTGGAGTTTTGTCTTGAAGAGCACAGAGAGAAGGTGAATG
CCACAGAAGAAATGCTGCAGCAGGAGCTTCTAAGTAGGACATCCTTAGAAACTCAGAAGTTGGATCTGATGGCTGAAATATCTAACTTGA
AGTTGAAACTGACAGCTGTAGAGAAGGACAGATTGGATTATGAAGATAAGTTCAGAGACACAGAGGGGCTGATTCAGGAGATCAATGATT
TGAGGTTAAAAGTTAGTGAAATGGACAGTGAGAGACTTCAGTATGAAAAAAAGCTTAAATCAACCAAATCTTTAATGGCCAAACTTTCTA
GCATGAAAATCAAGGTGGGTCAGATGCAGTATGAAAAGCAGCGGATGGAACAAAAATGGGAGTCACTGAAGGATGAACTGGCATCTTTAA
AAGAACAACTAGAAGAAAAGGAATCTGAAGTAAAAAGGCTACAAGAAAAATTGGTTTGCAAGATGAAAGGAGAAGGGGTTGAAATTGTTG
ATAGAGACATCGAAGTACAAAAAATGAAAAAAGCTGTGGAGTCCTTGATGGCAGCAAATGAAGAAAAGGATCGGAAAATAGAAGATCTTC
GACAGTGCCTGAACAGGTACAAGAAAATGCAAGACACGGTGGTACTGGCCCAAGGCAAAGATGGAGAATATGAAGAGCTGCTCAATTCCA
GTTCCATCTCCTCTTTGCTGGATGCACAGGGTTTCAGTGATCTGGAGAAAAGTCCATCACCCACTCCAGTAATGGGATCTCCCAGTTGTG
ACCCATTTAACACAAGTGTTCCCGAAGAGGAGGCAAGGAGAAAACGAAGAGAAAGAAATTTTGAAAAACAAAAGGAGAGGAAGAAGAAGA
GGCAGCAGGCTAGGAAGACTGCATCAGTTCTTAGTAAAGATGATGTGGCACCTGAAAGTGGTGATACTACAGTGAAGAAACCTGAATCAA
AGAAGGAACAGACCCCAGAGCATGGGAAGAAAAAACGTGGCAGAGGAAAAGCCCAAGTTAAAGCAACAAATGAATCCGAAGACGAAATCC
CACAGCTGGTACCAATAGGAAAGAAGACTCCAGCTAATGAAAAAGTAGAGATTCAAAAACATGCCACAGGAAAGAAGTCTCCAGCAAAGA
GTCCTAATCCCAGCACACCTCGTGGGAAGAAAAGAAAGGCTTTGCCAGCATCTGAGACCCCAAAAGCTGCAGAGTCTGAGACCCCAGGGA
AAAGCCCAGAGAAGAAGCCAAAAATCAAAGAAGAGGCAGTGAAGGAAAAAAGTCCTTCGCTGGGGAAAAAAGATGCGAGACAGACTCCAA
AAAAGCCAGAGGCCAAGTTTTTCACCACTCCTAGTAAATCTGTGAGAAAAGCTTCCCACACCCCCAAAAAATGGCCCAAAAAACCCAAAG

>67462_67462_5_PPFIBP1-RSL1D1_PPFIBP1_chr12_27820253_ENST00000537927_RSL1D1_chr16_11933842_ENST00000542106_length(amino acids)=519AA_BP=314
MLFKNTNGHLPGNGDVYQERLARLENDKESLVLQVSVLTDQVEAQGEKIRDLEFCLEEHREKVNATEEMLQQELLSRTSLETQKLDLMAE
ISNLKLKLTAVEKDRLDYEDKFRDTEGLIQEINDLRLKVSEMDSERLQYEKKLKSTKSLMAKLSSMKIKVGQMQYEKQRMEQKWESLKDE
LASLKEQLEEKESEVKRLQEKLVCKMKGEGVEIVDRDIEVQKMKKAVESLMAANEEKDRKIEDLRQCLNRYKKMQDTVVLAQGKDGEYEE
LLNSSSISSLLDAQGFSDLEKSPSPTPVMGSPSCDPFNTSVPEEEARRKRRERNFEKQKERKKKRQQARKTASVLSKDDVAPESGDTTVK
KPESKKEQTPEHGKKKRGRGKAQVKATNESEDEIPQLVPIGKKTPANEKVEIQKHATGKKSPAKSPNPSTPRGKKRKALPASETPKAAES

--------------------------------------------------------------
>67462_67462_6_PPFIBP1-RSL1D1_PPFIBP1_chr12_27820253_ENST00000537927_RSL1D1_chr16_11933842_ENST00000571133_length(transcript)=4405nt_BP=1199nt
CAGCTCCCAGCTCGGTGCCTGCCCGGATTCCTGACATGGTGTAGTGCAGGCAGGGTGGGGAAAGGACGGGGAAGGACTCGTGTGCTGCGA
GCTGGCGGCCGGGCCGGAGTGCTGGGGCTTTGAACTCCGAGAGGAGGTGGACCAGAACTTTTGGAACTAGTGCCGGCGGCTCTCCACCCC
CCAGTATAAAAGAACGTGTGGATCACTTTGCTGAGTACATCCAAGATTTGAAGAACTGAAATAAATCAGCTTTAAACCTGCTTTTTAAAA
ATACAAATGGACACCTACCAGGGAACGGAGATGTGTATCAAGAAAGGCTGGCACGTTTAGAAAATGATAAAGAATCCCTCGTTCTTCAGG
TAAGTGTGTTAACAGACCAGGTGGAGGCTCAGGGAGAGAAGATTCGAGATTTGGAGTTTTGTCTTGAAGAGCACAGAGAGAAGGTGAATG
CCACAGAAGAAATGCTGCAGCAGGAGCTTCTAAGTAGGACATCCTTAGAAACTCAGAAGTTGGATCTGATGGCTGAAATATCTAACTTGA
AGTTGAAACTGACAGCTGTAGAGAAGGACAGATTGGATTATGAAGATAAGTTCAGAGACACAGAGGGGCTGATTCAGGAGATCAATGATT
TGAGGTTAAAAGTTAGTGAAATGGACAGTGAGAGACTTCAGTATGAAAAAAAGCTTAAATCAACCAAATCTTTAATGGCCAAACTTTCTA
GCATGAAAATCAAGGTGGGTCAGATGCAGTATGAAAAGCAGCGGATGGAACAAAAATGGGAGTCACTGAAGGATGAACTGGCATCTTTAA
AAGAACAACTAGAAGAAAAGGAATCTGAAGTAAAAAGGCTACAAGAAAAATTGGTTTGCAAGATGAAAGGAGAAGGGGTTGAAATTGTTG
ATAGAGACATCGAAGTACAAAAAATGAAAAAAGCTGTGGAGTCCTTGATGGCAGCAAATGAAGAAAAGGATCGGAAAATAGAAGATCTTC
GACAGTGCCTGAACAGGTACAAGAAAATGCAAGACACGGTGGTACTGGCCCAAGGCAAAGATGGAGAATATGAAGAGCTGCTCAATTCCA
GTTCCATCTCCTCTTTGCTGGATGCACAGGGTTTCAGTGATCTGGAGAAAAGTCCATCACCCACTCCAGTAATGGGATCTCCCAGTTGTG
ACCCATTTAACACAAGTGTTCCCGAAGAGGAGGCAAGGAGAAAACGAAGAGAAAGAAATTTTGAAAAACAAAAGGAGAGGAAGAAGAAGA
GGCAGCAGGCTAGGAAGACTGCATCAGTTCTTAGTAAAGATGATGTGGCACCTGAAAGTGGTGATACTACAGTGAAGAAACCTGAATCAA
AGAAGGAACAGACCCCAGAGCATGGGAAGAAAAAACGTGGCAGAGGAAAAGCCCAAGTTAAAGCAACAAATGAATCCGAAGACGAAATCC
CACAGCTGGTACCAATAGGAAAGAAGACTCCAGCTAATGAAAAAGTAGAGATTCAAAAACATGCCACAGGAAAGAAGTCTCCAGCAAAGA
GTCCTAATCCCAGCACACCTCGTGGGAAGAAAAGAAAGGCTTTGCCAGCATCTGAGACCCCAAAAGCTGCAGAGTCTGAGACCCCAGGGA
AAAGCCCAGAGAAGAAGCCAAAAATCAAAGAAGAGGCAGTGAAGGAAAAAAGTCCTTCGCTGGGGAAAAAAGATGCGAGACAGACTCCAA
AAAAGCCAGAGGCCAAGTTTTTCACCACTCCTAGTAAATCTGTGAGAAAAGCTTCCCACACCCCCAAAAAATGGCCCAAAAAACCCAAAG
TACCCCAGTCGACCTAAAGTCAGTGATTCAACTGGAAGGAAACCTCAATGCTGCCTCCAGAGCTTTTTGGAAATACTCAGATCCTGGCCG
CCTTTGTAACCTTCTCTAAACGTCAGGCCTGGACTTAAAAGATTTTTTAAAACCTCCATAAGTAGTCCAGGGGCGGTGGCTCACGCCTGT
AATCCCAGCACTTTGGGAGGCCGAGGCAGGCGGATCACAAGGTCAACGAGATCGAGACCATCCTGGCCAACATGGTGAAACCCTGTCTGT
ACCAAAAATACAAAAATTAATTGGGCATGGTGGTGGACACCTGTAATCCCAGCTACTAGGGAGGCTGAGGCAGGAGAATTGCTTGAACCT
GGGAGGCGGAGGTTGCAGTGAGCCACTGCACTCCAGCCTGATGACAGAGCAAGACTCAGTCTCAAAAATAAATAAAAATAATAAAACCTC
CATAAGTAATCCTGACATATGTTCCTGGGTATAATCTGTTTCTAAATTGTCCTTCTGTGTATTTGCTAATGTAATAGAGGGAAAAATAGA
GTGCTTCTCTGTGGTTGTTCAGCACTTTAGGTAGCCAAGGTGAGAGGATTGCTTGAGGCCAGGAGTTTGAGACTAGCCTGGGCAACTTGG
TAAAACCCCATCTCTACAAAAGAAAAAAAAAAATTAGTGTGGCATGGTGGCATGCATCTGTGCTCCCAGCTCCTCACGAGGCTGAGGTGG
AAGGATCAAGTGAGCGCAAGAGGTTGAGGCTCCAGTGAGCCACGATCACCCCACTGTGCTGTAGCCTGGGTGACAGTGTGAGATTCTGTC
TCAGAAAAAACAAAGTATAACATTGCTTTGCTTCTGAGTATACTGTTGGCTTTCCAAATCAGTGGGTCTGACTTGAGGTCTGTGATGTGA
CCCTTTTCCTCACCTGCTCAACCATTATTCACATGGACTCCATCATATTCATTTGTAGTCATTCCCAGAGTGGCCCAGTGAGGGTCTCGC
TGTATGAGAGTCGGCTACGGAATTTAGGAGAAACAGAAGTTTCTTGGCTTTCATGCTGAGCTTGTTGGTCTAAGCTTATGAGTCACTGGA
TTAGCATCCATATGGGAAGGGAAATTAACATGGAGTCATTTATACAGGGACTAAATTGAATCCTACCTACCGGAGGCAAGAACATGATTT
ATCTTCCATAAGCCTTATCCTCTTCCTCCTTATTCCTCAGTCCATATGGATTTGCTTATGTATGACAACTCCAAGGAATCTTGGAAGAGT
AGATTGCTAACGTTTCCACAATTGTCAAGTATATTCTGAGGCAGTAAACACCTTTTTAGGTACGTGGCCTTTCACTGGTTGTGAATTGGT
ATGCATCCGTAGTAGTAAGTTCACAGATTCACTGCAGTGCAGGAATGTTCTTGCATGCCAAAGACTCAACTGCTTTCAAAGATAATGTGG
GTGCTAGATGCAGTGGCTTACATCTGTAACCCTGTTAGGGTGACCAGACCCAACACCAGGTCGTGGGGGTGACAAAGTCCAGTGGAGTCA
AAGGATTGAGAAAAAGACAGTTTGAGAGAGAAGTAGGACCAGCAGACCATCGGGATGGTGGAGGCTGTGAAGGCCGTGAGCTCTGGGAGC
CCACACTATTTATTGGTAATCCAACAAAGAAACAGATGGTGAGAATGTGAAGGTCAGAAGGGCACCTTGCATTAAGCACATGATTTACAG
CTGTGATGGTTTAGCATTTGCTCTGCTACTTGAGATGATGGAGAGCAGGTTCTTTTAACTCAAGTTACAGTCGATCCTGGGAGAGCAAGG
AGCCAGCAAGTCTAGACATTCCAGAGCCACAGGCCCTGGATTTTATCCAAGCCACGAGGGATTTTATGCCCTGGGCTTAGATTATGGTGC
GTCAGGGCAGCCTTCCACCCTTTAGCACAGAGCTTGGTGTTCCAAAGACCACAAGGGGTTTTAGACCCTTGACCCTGGACATATTCCAAG
ACTCTTTTACATTATGTCAGAATGCAAGCCCTGCCTCAGCTTCTCCCAACACTCAGCTTTTCGCAACATAATCCCAGCACTTTGGAACGC
TGGGTGGATTGCTTGAACCCAGGAGTTCGAGACCATCCTGGGCAATATGGCAAAACCCCATCTTTACCAAAAATAAGCTGGGTGTGGTGG
AACATGCCTGTGGTCCCAGCTTCTTGGGAGGCTGAGGTGGGAGGATTGCTTGAACCCGGGAGGTAGAGGCTGCAATGGGCCATGATCACG
ATCCTGCACTCCAGCCTGGGCAACAGAGAGAGACAGTCCCTGGCCCACTGCCCCCTTCCCTGGCCCAGTCTCAAAAAAAATGAGGCTGGG
CGTGGTGGCTCACATCTGTAATCCCAGCCAAGGCTGGCAGATCACTTGAGGCCAGGAGTTCTGAGACCAGCCTGGCTTACATGGTGAAAC
CCCATCTCTACTAAAAATACAAAAACTAGCCAGGCATGGTGGGAGGCACCTGTAATCCCAGCTACTTGGGAGGCTGAAGCAGGAGAATCA

>67462_67462_6_PPFIBP1-RSL1D1_PPFIBP1_chr12_27820253_ENST00000537927_RSL1D1_chr16_11933842_ENST00000571133_length(amino acids)=519AA_BP=314
MLFKNTNGHLPGNGDVYQERLARLENDKESLVLQVSVLTDQVEAQGEKIRDLEFCLEEHREKVNATEEMLQQELLSRTSLETQKLDLMAE
ISNLKLKLTAVEKDRLDYEDKFRDTEGLIQEINDLRLKVSEMDSERLQYEKKLKSTKSLMAKLSSMKIKVGQMQYEKQRMEQKWESLKDE
LASLKEQLEEKESEVKRLQEKLVCKMKGEGVEIVDRDIEVQKMKKAVESLMAANEEKDRKIEDLRQCLNRYKKMQDTVVLAQGKDGEYEE
LLNSSSISSLLDAQGFSDLEKSPSPTPVMGSPSCDPFNTSVPEEEARRKRRERNFEKQKERKKKRQQARKTASVLSKDDVAPESGDTTVK
KPESKKEQTPEHGKKKRGRGKAQVKATNESEDEIPQLVPIGKKTPANEKVEIQKHATGKKSPAKSPNPSTPRGKKRKALPASETPKAAES

--------------------------------------------------------------
>67462_67462_7_PPFIBP1-RSL1D1_PPFIBP1_chr12_27820253_ENST00000542629_RSL1D1_chr16_11933842_ENST00000542106_length(transcript)=2056nt_BP=1369nt
AGTGCAGGCAGGGTGGGGAAAGGACGGGGAAGGACTCGTGTGCTGCGAGCTGGCGGCCGGGCCGGAGTGCTGGGGCTTTGAACTCCGAGA
GGAGGTGGACCAGAACTTTTGGAACTAGTGCCGGCGGCTCTCCACCCCCCAGTATAAAAGAACGTGTGGATCACTTTGCTGAGTACATCC
AAGATTTGAAGAACTGAAATAAATCAGCTTTAAACCTGCTTTTTAAAAATATCTGGGTTGGAATTTGCCCCTGACAAATAATAAAATGAT
GAGTGATGCAAGTGACATGTTGGCTGCAGCGTTGGAGCAGATGGATGGTATCATAGCAGGTTCTAAGGCTCTGGAATATTCCAATGGGAT
TTTTGATTGCCAATCTCCCACCTCTCCATTCATGGGAAGTTTGCGAGCTCTGCACCTTGTGGAAGACCTGCGTGGATTGTTAGAGATGAT
GGAAACAGATGAGAAAGAAGGCTTGAGATGCCAGATCCCAGATTCAACAGCAGAAACGCTTGTTGAATGGCTTCAGAGTCAAATGACAAA
TGGACACCTACCAGGGAACGGAGATGTGTATCAAGAAAGGCTGGCACGTTTAGAAAATGATAAAGAATCCCTCGTTCTTCAGGTAAGTGT
GTTAACAGACCAGGTGGAGGCTCAGGGAGAGAAGATTCGAGATTTGGAGTTTTGTCTTGAAGAGCACAGAGAGAAGGTGAATGCCACAGA
AGAAATGCTGCAGCAGGAGCTTCTAAGTAGGACATCCTTAGAAACTCAGAAGTTGGATCTGATGGCTGAAATATCTAACTTGAAGTTGAA
ACTGACAGCTGTAGAGAAGGACAGATTGGATTATGAAGATAAGTTCAGAGACACAGAGGGGCTGATTCAGGAGATCAATGATTTGAGGTT
AAAAGTTAGTGAAATGGACAGTGAGAGACTTCAGTATGAAAAAAAGCTTAAATCAACCAAAGATGAACTGGCATCTTTAAAAGAACAACT
AGAAGAAAAGGAATCTGAAGTAAAAAGGCTACAAGAAAAATTGGTTTGCAAGATGAAAGGAGAAGGGGTTGAAATTGTTGATAGAGACAT
CGAAGTACAAAAAATGAAAAAAGCTGTGGAGTCCTTGATGGCAGCAAATGAAGAAAAGGATCGGAAAATAGAAGATCTTCGACAGTGCCT
GAACAGGTACAAGAAAATGCAAGACACGGTGGTACTGGCCCAAGGCAAAGATGGAGAATATGAAGAGCTGCTCAATTCCAGTTCCATCTC
CTCTTTGCTGGATGCACAGGGTTTCAGTGATCTGGAGAAAAGTCCATCACCCACTCCAGTAATGGGATCTCCCAGTTGTGACCCATTTAA
CACAAGTGTTCCCGAAGAGGAGGCAAGGAGAAAACGAAGAGAAAGAAATTTTGAAAAACAAAAGGAGAGGAAGAAGAAGAGGCAGCAGGC
TAGGAAGACTGCATCAGTTCTTAGTAAAGATGATGTGGCACCTGAAAGTGGTGATACTACAGTGAAGAAACCTGAATCAAAGAAGGAACA
GACCCCAGAGCATGGGAAGAAAAAACGTGGCAGAGGAAAAGCCCAAGTTAAAGCAACAAATGAATCCGAAGACGAAATCCCACAGCTGGT
ACCAATAGGAAAGAAGACTCCAGCTAATGAAAAAGTAGAGATTCAAAAACATGCCACAGGAAAGAAGTCTCCAGCAAAGAGTCCTAATCC
CAGCACACCTCGTGGGAAGAAAAGAAAGGCTTTGCCAGCATCTGAGACCCCAAAAGCTGCAGAGTCTGAGACCCCAGGGAAAAGCCCAGA
GAAGAAGCCAAAAATCAAAGAAGAGGCAGTGAAGGAAAAAAGTCCTTCGCTGGGGAAAAAAGATGCGAGACAGACTCCAAAAAAGCCAGA
GGCCAAGTTTTTCACCACTCCTAGTAAATCTGTGAGAAAAGCTTCCCACACCCCCAAAAAATGGCCCAAAAAACCCAAAGTACCCCAGTC

>67462_67462_7_PPFIBP1-RSL1D1_PPFIBP1_chr12_27820253_ENST00000542629_RSL1D1_chr16_11933842_ENST00000542106_length(amino acids)=584AA_BP=379
MGWNLPLTNNKMMSDASDMLAAALEQMDGIIAGSKALEYSNGIFDCQSPTSPFMGSLRALHLVEDLRGLLEMMETDEKEGLRCQIPDSTA
ETLVEWLQSQMTNGHLPGNGDVYQERLARLENDKESLVLQVSVLTDQVEAQGEKIRDLEFCLEEHREKVNATEEMLQQELLSRTSLETQK
LDLMAEISNLKLKLTAVEKDRLDYEDKFRDTEGLIQEINDLRLKVSEMDSERLQYEKKLKSTKDELASLKEQLEEKESEVKRLQEKLVCK
MKGEGVEIVDRDIEVQKMKKAVESLMAANEEKDRKIEDLRQCLNRYKKMQDTVVLAQGKDGEYEELLNSSSISSLLDAQGFSDLEKSPSP
TPVMGSPSCDPFNTSVPEEEARRKRRERNFEKQKERKKKRQQARKTASVLSKDDVAPESGDTTVKKPESKKEQTPEHGKKKRGRGKAQVK
ATNESEDEIPQLVPIGKKTPANEKVEIQKHATGKKSPAKSPNPSTPRGKKRKALPASETPKAAESETPGKSPEKKPKIKEEAVKEKSPSL

--------------------------------------------------------------
>67462_67462_8_PPFIBP1-RSL1D1_PPFIBP1_chr12_27820253_ENST00000542629_RSL1D1_chr16_11933842_ENST00000571133_length(transcript)=4575nt_BP=1369nt
AGTGCAGGCAGGGTGGGGAAAGGACGGGGAAGGACTCGTGTGCTGCGAGCTGGCGGCCGGGCCGGAGTGCTGGGGCTTTGAACTCCGAGA
GGAGGTGGACCAGAACTTTTGGAACTAGTGCCGGCGGCTCTCCACCCCCCAGTATAAAAGAACGTGTGGATCACTTTGCTGAGTACATCC
AAGATTTGAAGAACTGAAATAAATCAGCTTTAAACCTGCTTTTTAAAAATATCTGGGTTGGAATTTGCCCCTGACAAATAATAAAATGAT
GAGTGATGCAAGTGACATGTTGGCTGCAGCGTTGGAGCAGATGGATGGTATCATAGCAGGTTCTAAGGCTCTGGAATATTCCAATGGGAT
TTTTGATTGCCAATCTCCCACCTCTCCATTCATGGGAAGTTTGCGAGCTCTGCACCTTGTGGAAGACCTGCGTGGATTGTTAGAGATGAT
GGAAACAGATGAGAAAGAAGGCTTGAGATGCCAGATCCCAGATTCAACAGCAGAAACGCTTGTTGAATGGCTTCAGAGTCAAATGACAAA
TGGACACCTACCAGGGAACGGAGATGTGTATCAAGAAAGGCTGGCACGTTTAGAAAATGATAAAGAATCCCTCGTTCTTCAGGTAAGTGT
GTTAACAGACCAGGTGGAGGCTCAGGGAGAGAAGATTCGAGATTTGGAGTTTTGTCTTGAAGAGCACAGAGAGAAGGTGAATGCCACAGA
AGAAATGCTGCAGCAGGAGCTTCTAAGTAGGACATCCTTAGAAACTCAGAAGTTGGATCTGATGGCTGAAATATCTAACTTGAAGTTGAA
ACTGACAGCTGTAGAGAAGGACAGATTGGATTATGAAGATAAGTTCAGAGACACAGAGGGGCTGATTCAGGAGATCAATGATTTGAGGTT
AAAAGTTAGTGAAATGGACAGTGAGAGACTTCAGTATGAAAAAAAGCTTAAATCAACCAAAGATGAACTGGCATCTTTAAAAGAACAACT
AGAAGAAAAGGAATCTGAAGTAAAAAGGCTACAAGAAAAATTGGTTTGCAAGATGAAAGGAGAAGGGGTTGAAATTGTTGATAGAGACAT
CGAAGTACAAAAAATGAAAAAAGCTGTGGAGTCCTTGATGGCAGCAAATGAAGAAAAGGATCGGAAAATAGAAGATCTTCGACAGTGCCT
GAACAGGTACAAGAAAATGCAAGACACGGTGGTACTGGCCCAAGGCAAAGATGGAGAATATGAAGAGCTGCTCAATTCCAGTTCCATCTC
CTCTTTGCTGGATGCACAGGGTTTCAGTGATCTGGAGAAAAGTCCATCACCCACTCCAGTAATGGGATCTCCCAGTTGTGACCCATTTAA
CACAAGTGTTCCCGAAGAGGAGGCAAGGAGAAAACGAAGAGAAAGAAATTTTGAAAAACAAAAGGAGAGGAAGAAGAAGAGGCAGCAGGC
TAGGAAGACTGCATCAGTTCTTAGTAAAGATGATGTGGCACCTGAAAGTGGTGATACTACAGTGAAGAAACCTGAATCAAAGAAGGAACA
GACCCCAGAGCATGGGAAGAAAAAACGTGGCAGAGGAAAAGCCCAAGTTAAAGCAACAAATGAATCCGAAGACGAAATCCCACAGCTGGT
ACCAATAGGAAAGAAGACTCCAGCTAATGAAAAAGTAGAGATTCAAAAACATGCCACAGGAAAGAAGTCTCCAGCAAAGAGTCCTAATCC
CAGCACACCTCGTGGGAAGAAAAGAAAGGCTTTGCCAGCATCTGAGACCCCAAAAGCTGCAGAGTCTGAGACCCCAGGGAAAAGCCCAGA
GAAGAAGCCAAAAATCAAAGAAGAGGCAGTGAAGGAAAAAAGTCCTTCGCTGGGGAAAAAAGATGCGAGACAGACTCCAAAAAAGCCAGA
GGCCAAGTTTTTCACCACTCCTAGTAAATCTGTGAGAAAAGCTTCCCACACCCCCAAAAAATGGCCCAAAAAACCCAAAGTACCCCAGTC
GACCTAAAGTCAGTGATTCAACTGGAAGGAAACCTCAATGCTGCCTCCAGAGCTTTTTGGAAATACTCAGATCCTGGCCGCCTTTGTAAC
CTTCTCTAAACGTCAGGCCTGGACTTAAAAGATTTTTTAAAACCTCCATAAGTAGTCCAGGGGCGGTGGCTCACGCCTGTAATCCCAGCA
CTTTGGGAGGCCGAGGCAGGCGGATCACAAGGTCAACGAGATCGAGACCATCCTGGCCAACATGGTGAAACCCTGTCTGTACCAAAAATA
CAAAAATTAATTGGGCATGGTGGTGGACACCTGTAATCCCAGCTACTAGGGAGGCTGAGGCAGGAGAATTGCTTGAACCTGGGAGGCGGA
GGTTGCAGTGAGCCACTGCACTCCAGCCTGATGACAGAGCAAGACTCAGTCTCAAAAATAAATAAAAATAATAAAACCTCCATAAGTAAT
CCTGACATATGTTCCTGGGTATAATCTGTTTCTAAATTGTCCTTCTGTGTATTTGCTAATGTAATAGAGGGAAAAATAGAGTGCTTCTCT
GTGGTTGTTCAGCACTTTAGGTAGCCAAGGTGAGAGGATTGCTTGAGGCCAGGAGTTTGAGACTAGCCTGGGCAACTTGGTAAAACCCCA
TCTCTACAAAAGAAAAAAAAAAATTAGTGTGGCATGGTGGCATGCATCTGTGCTCCCAGCTCCTCACGAGGCTGAGGTGGAAGGATCAAG
TGAGCGCAAGAGGTTGAGGCTCCAGTGAGCCACGATCACCCCACTGTGCTGTAGCCTGGGTGACAGTGTGAGATTCTGTCTCAGAAAAAA
CAAAGTATAACATTGCTTTGCTTCTGAGTATACTGTTGGCTTTCCAAATCAGTGGGTCTGACTTGAGGTCTGTGATGTGACCCTTTTCCT
CACCTGCTCAACCATTATTCACATGGACTCCATCATATTCATTTGTAGTCATTCCCAGAGTGGCCCAGTGAGGGTCTCGCTGTATGAGAG
TCGGCTACGGAATTTAGGAGAAACAGAAGTTTCTTGGCTTTCATGCTGAGCTTGTTGGTCTAAGCTTATGAGTCACTGGATTAGCATCCA
TATGGGAAGGGAAATTAACATGGAGTCATTTATACAGGGACTAAATTGAATCCTACCTACCGGAGGCAAGAACATGATTTATCTTCCATA
AGCCTTATCCTCTTCCTCCTTATTCCTCAGTCCATATGGATTTGCTTATGTATGACAACTCCAAGGAATCTTGGAAGAGTAGATTGCTAA
CGTTTCCACAATTGTCAAGTATATTCTGAGGCAGTAAACACCTTTTTAGGTACGTGGCCTTTCACTGGTTGTGAATTGGTATGCATCCGT
AGTAGTAAGTTCACAGATTCACTGCAGTGCAGGAATGTTCTTGCATGCCAAAGACTCAACTGCTTTCAAAGATAATGTGGGTGCTAGATG
CAGTGGCTTACATCTGTAACCCTGTTAGGGTGACCAGACCCAACACCAGGTCGTGGGGGTGACAAAGTCCAGTGGAGTCAAAGGATTGAG
AAAAAGACAGTTTGAGAGAGAAGTAGGACCAGCAGACCATCGGGATGGTGGAGGCTGTGAAGGCCGTGAGCTCTGGGAGCCCACACTATT
TATTGGTAATCCAACAAAGAAACAGATGGTGAGAATGTGAAGGTCAGAAGGGCACCTTGCATTAAGCACATGATTTACAGCTGTGATGGT
TTAGCATTTGCTCTGCTACTTGAGATGATGGAGAGCAGGTTCTTTTAACTCAAGTTACAGTCGATCCTGGGAGAGCAAGGAGCCAGCAAG
TCTAGACATTCCAGAGCCACAGGCCCTGGATTTTATCCAAGCCACGAGGGATTTTATGCCCTGGGCTTAGATTATGGTGCGTCAGGGCAG
CCTTCCACCCTTTAGCACAGAGCTTGGTGTTCCAAAGACCACAAGGGGTTTTAGACCCTTGACCCTGGACATATTCCAAGACTCTTTTAC
ATTATGTCAGAATGCAAGCCCTGCCTCAGCTTCTCCCAACACTCAGCTTTTCGCAACATAATCCCAGCACTTTGGAACGCTGGGTGGATT
GCTTGAACCCAGGAGTTCGAGACCATCCTGGGCAATATGGCAAAACCCCATCTTTACCAAAAATAAGCTGGGTGTGGTGGAACATGCCTG
TGGTCCCAGCTTCTTGGGAGGCTGAGGTGGGAGGATTGCTTGAACCCGGGAGGTAGAGGCTGCAATGGGCCATGATCACGATCCTGCACT
CCAGCCTGGGCAACAGAGAGAGACAGTCCCTGGCCCACTGCCCCCTTCCCTGGCCCAGTCTCAAAAAAAATGAGGCTGGGCGTGGTGGCT
CACATCTGTAATCCCAGCCAAGGCTGGCAGATCACTTGAGGCCAGGAGTTCTGAGACCAGCCTGGCTTACATGGTGAAACCCCATCTCTA
CTAAAAATACAAAAACTAGCCAGGCATGGTGGGAGGCACCTGTAATCCCAGCTACTTGGGAGGCTGAAGCAGGAGAATCACTTTAACCCG

>67462_67462_8_PPFIBP1-RSL1D1_PPFIBP1_chr12_27820253_ENST00000542629_RSL1D1_chr16_11933842_ENST00000571133_length(amino acids)=584AA_BP=379
MGWNLPLTNNKMMSDASDMLAAALEQMDGIIAGSKALEYSNGIFDCQSPTSPFMGSLRALHLVEDLRGLLEMMETDEKEGLRCQIPDSTA
ETLVEWLQSQMTNGHLPGNGDVYQERLARLENDKESLVLQVSVLTDQVEAQGEKIRDLEFCLEEHREKVNATEEMLQQELLSRTSLETQK
LDLMAEISNLKLKLTAVEKDRLDYEDKFRDTEGLIQEINDLRLKVSEMDSERLQYEKKLKSTKDELASLKEQLEEKESEVKRLQEKLVCK
MKGEGVEIVDRDIEVQKMKKAVESLMAANEEKDRKIEDLRQCLNRYKKMQDTVVLAQGKDGEYEELLNSSSISSLLDAQGFSDLEKSPSP
TPVMGSPSCDPFNTSVPEEEARRKRRERNFEKQKERKKKRQQARKTASVLSKDDVAPESGDTTVKKPESKKEQTPEHGKKKRGRGKAQVK
ATNESEDEIPQLVPIGKKTPANEKVEIQKHATGKKSPAKSPNPSTPRGKKRKALPASETPKAAESETPGKSPEKKPKIKEEAVKEKSPSL

--------------------------------------------------------------

Top

Fusion Gene PPI Analysis for PPFIBP1-RSL1D1


check button Go to ChiPPI (Chimeric Protein-Protein interactions) to see the chimeric PPI interaction in

ChiPPI page.


check button Protein-protein interactors with each fusion partner protein in wild-type (BIOGRID-3.4.160)
HgeneHgene's interactorsTgeneTgene's interactors


check button - Retained PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenStill interaction with


check button - Lost PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


check button - Retained PPIs, but lost function due to frame-shift fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


Top

Related Drugs for PPFIBP1-RSL1D1


check button Drugs targeting genes involved in this fusion gene.
(DrugBank Version 5.1.8 2021-05-08)
PartnerGeneUniProtAccDrugBank IDDrug nameDrug activityDrug typeDrug status

Top

Related Diseases for PPFIBP1-RSL1D1


check button Diseases associated with fusion partners.
(DisGeNet 4.0)
PartnerGeneDisease IDDisease name# pubmedsSource