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Center for Computational Systems Medicine
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Fusion Gene Summary

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Fusion Gene ORF analysis

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Fusion Genomic Features

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Fusion Protein Features

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Fusion Gene Sequence

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Fusion Gene PPI analysis

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Related Drugs

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Related Diseases

Fusion gene:PPP1R12B-LGR6 (FusionGDB2 ID:67767)

Fusion Gene Summary for PPP1R12B-LGR6

check button Fusion gene summary
Fusion gene informationFusion gene name: PPP1R12B-LGR6
Fusion gene ID: 67767
HgeneTgene
Gene symbol

PPP1R12B

LGR6

Gene ID

4660

59352

Gene nameprotein phosphatase 1 regulatory subunit 12Bleucine rich repeat containing G protein-coupled receptor 6
SynonymsMYPT2|PP1bp55GPCR|VTS20631
Cytomap

1q32.1

1q32.1

Type of geneprotein-codingprotein-coding
Descriptionprotein phosphatase 1 regulatory subunit 12Bmyosin phosphatase target subunit 2myosin phosphatase-targeting subunit 2protein phosphatase 1, regulatory (inhibitor) subunit 12Bleucine-rich repeat-containing G-protein coupled receptor 6gonadotropin receptor
Modification date2020031320200313
UniProtAcc.

Q9HBX8

Ensembl transtripts involved in fusion geneENST00000336894, ENST00000356764, 
ENST00000480184, ENST00000608999, 
ENST00000290419, ENST00000367270, 
ENST00000391959, 		ENST00000308543, 
ENST00000439764, ENST00000255432, 
ENST00000367278, 
Fusion gene scores* DoF score12 X 9 X 4=4322 X 2 X 2=8
# samples 122
** MAII scorelog2(12/432*10)=-1.84799690655495
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0		log2(2/8*10)=1.32192809488736
Context

PubMed: PPP1R12B [Title/Abstract] AND LGR6 [Title/Abstract] AND fusion [Title/Abstract]

Most frequent breakpointPPP1R12B(202386045)-LGR6(202245434), # samples:1
Anticipated loss of major functional domain due to fusion event.
* DoF score (Degree of Frequency) = # partners X # break points X # cancer types
** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10)

check button Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez
PartnerGeneGO IDGO termPubMed ID
TgeneLGR6

GO:0030177

positive regulation of Wnt signaling pathway

22615920

TgeneLGR6

GO:0030335

positive regulation of cell migration

22615920


check buttonFusion gene breakpoints across PPP1R12B (5'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.
all structure

check buttonFusion gene breakpoints across LGR6 (3'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.
all structure

check button Fusion gene information from two resources (ChiTars 5.0 and ChimerDB 4.0)
* All genome coordinats were lifted-over on hg19.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
SourceDiseaseSampleHgeneHchrHbpHstrandTgeneTchrTbpTstrand
ChimerDB4LUSCTCGA-37-4130-01APPP1R12Bchr1

202386045

-LGR6chr1

202245434

+


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Fusion Gene ORF analysis for PPP1R12B-LGR6

check button Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
ORFHenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrand
5CDS-3UTRENST00000336894ENST00000308543PPP1R12Bchr1

202386045

-LGR6chr1

202245434

+
5CDS-3UTRENST00000356764ENST00000308543PPP1R12Bchr1

202386045

-LGR6chr1

202245434

+
5CDS-3UTRENST00000480184ENST00000308543PPP1R12Bchr1

202386045

-LGR6chr1

202245434

+
5CDS-3UTRENST00000608999ENST00000308543PPP1R12Bchr1

202386045

-LGR6chr1

202245434

+
5CDS-intronENST00000336894ENST00000439764PPP1R12Bchr1

202386045

-LGR6chr1

202245434

+
5CDS-intronENST00000356764ENST00000439764PPP1R12Bchr1

202386045

-LGR6chr1

202245434

+
5CDS-intronENST00000480184ENST00000439764PPP1R12Bchr1

202386045

-LGR6chr1

202245434

+
5CDS-intronENST00000608999ENST00000439764PPP1R12Bchr1

202386045

-LGR6chr1

202245434

+
In-frameENST00000336894ENST00000255432PPP1R12Bchr1

202386045

-LGR6chr1

202245434

+
In-frameENST00000336894ENST00000367278PPP1R12Bchr1

202386045

-LGR6chr1

202245434

+
In-frameENST00000356764ENST00000255432PPP1R12Bchr1

202386045

-LGR6chr1

202245434

+
In-frameENST00000356764ENST00000367278PPP1R12Bchr1

202386045

-LGR6chr1

202245434

+
In-frameENST00000480184ENST00000255432PPP1R12Bchr1

202386045

-LGR6chr1

202245434

+
In-frameENST00000480184ENST00000367278PPP1R12Bchr1

202386045

-LGR6chr1

202245434

+
In-frameENST00000608999ENST00000255432PPP1R12Bchr1

202386045

-LGR6chr1

202245434

+
In-frameENST00000608999ENST00000367278PPP1R12Bchr1

202386045

-LGR6chr1

202245434

+
intron-3CDSENST00000290419ENST00000255432PPP1R12Bchr1

202386045

-LGR6chr1

202245434

+
intron-3CDSENST00000290419ENST00000367278PPP1R12Bchr1

202386045

-LGR6chr1

202245434

+
intron-3CDSENST00000367270ENST00000255432PPP1R12Bchr1

202386045

-LGR6chr1

202245434

+
intron-3CDSENST00000367270ENST00000367278PPP1R12Bchr1

202386045

-LGR6chr1

202245434

+
intron-3CDSENST00000391959ENST00000255432PPP1R12Bchr1

202386045

-LGR6chr1

202245434

+
intron-3CDSENST00000391959ENST00000367278PPP1R12Bchr1

202386045

-LGR6chr1

202245434

+
intron-3UTRENST00000290419ENST00000308543PPP1R12Bchr1

202386045

-LGR6chr1

202245434

+
intron-3UTRENST00000367270ENST00000308543PPP1R12Bchr1

202386045

-LGR6chr1

202245434

+
intron-3UTRENST00000391959ENST00000308543PPP1R12Bchr1

202386045

-LGR6chr1

202245434

+
intron-intronENST00000290419ENST00000439764PPP1R12Bchr1

202386045

-LGR6chr1

202245434

+
intron-intronENST00000367270ENST00000439764PPP1R12Bchr1

202386045

-LGR6chr1

202245434

+
intron-intronENST00000391959ENST00000439764PPP1R12Bchr1

202386045

-LGR6chr1

202245434

+

check buttonORFfinder result based on the fusion transcript sequence of in-frame fusion genes.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandSeq length
(transcript)		BP loci
(transcript)		Predicted start
(transcript)		Predicted stop
(transcript)		Seq length
(amino acids)
ENST00000608999PPP1R12Bchr1202386045-ENST00000367278LGR6chr1202245434+3625575603050996
ENST00000608999PPP1R12Bchr1202386045-ENST00000255432LGR6chr1202245434+3625575603050996
ENST00000336894PPP1R12Bchr1202386045-ENST00000367278LGR6chr1202245434+3622572573047996
ENST00000336894PPP1R12Bchr1202386045-ENST00000255432LGR6chr1202245434+3622572573047996
ENST00000480184PPP1R12Bchr1202386045-ENST00000367278LGR6chr1202245434+3604554393029996
ENST00000480184PPP1R12Bchr1202386045-ENST00000255432LGR6chr1202245434+3604554393029996
ENST00000356764PPP1R12Bchr1202386045-ENST00000367278LGR6chr1202245434+3596546313021996
ENST00000356764PPP1R12Bchr1202386045-ENST00000255432LGR6chr1202245434+3596546313021996

check buttonDeepORF prediction of the coding potential based on the fusion transcript sequence of in-frame fusion genes. DeepORF is a coding potential classifier based on convolutional neural network by comparing the real Ribo-seq data. If the no-coding score < 0.5 and coding score > 0.5, then the in-frame fusion transcript is predicted as being likely translated.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandNo-coding scoreCoding score
ENST00000608999ENST00000367278PPP1R12Bchr1202386045-LGR6chr1202245434+0.0022230360.9977769
ENST00000608999ENST00000255432PPP1R12Bchr1202386045-LGR6chr1202245434+0.0022230360.9977769
ENST00000336894ENST00000367278PPP1R12Bchr1202386045-LGR6chr1202245434+0.0022911530.9977088
ENST00000336894ENST00000255432PPP1R12Bchr1202386045-LGR6chr1202245434+0.0022911530.9977088
ENST00000480184ENST00000367278PPP1R12Bchr1202386045-LGR6chr1202245434+0.0023701030.9976299
ENST00000480184ENST00000255432PPP1R12Bchr1202386045-LGR6chr1202245434+0.0023701030.9976299
ENST00000356764ENST00000367278PPP1R12Bchr1202386045-LGR6chr1202245434+0.0023330770.99766695
ENST00000356764ENST00000255432PPP1R12Bchr1202386045-LGR6chr1202245434+0.0023330770.99766695

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Fusion Genomic Features for PPP1R12B-LGR6


check buttonFusionAI prediction of the potential fusion gene breakpoint based on the pre-mature RNA sequence context (+/- 5kb of individual partner genes, total 20kb length sequence). FusionAI is a fusion gene breakpoint classifier based on convolutional neural network by comparing the fusion positive and negative sequence context of ~ 20K fusion gene data. From here, we can have the relative potentency of the 20K genomic sequence how individual sequnce will be likely used as the gene fusion breakpoints.
HgeneHchrHbpHstrandTgeneTchrTbpTstrand1-pp (fusion gene breakpoint)

check buttonDistribution of 44 human genomic features loci across 20kb length fusion breakpoint regions. We integrated a total of 44 different types of human genomic feature loci information across five big categories including virus integration sites, repeats, structural variants, chromatin states, and gene expression regulation. More details are in help page.
genomic feature

check buttonDistribution of 44 human genomic features loci across 20kb length fusion breakpoint regions that are ovelapped with the top 1% feature importance score regions. More details are in help page.

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Fusion Protein Features for PPP1R12B-LGR6


check button Four levels of functional features of fusion genes
Go to FGviewer search page for the most frequent breakpoint (https://ccsmweb.uth.edu/FGviewer/chr1:202386045/chr1:202245434)
- FGviewer provides the online visualization of the retention search of the protein functional features across DNA, RNA, protein, and pathological levels.
- How to search
1. Put your fusion gene symbol.
2. Press the tab key until there will be shown the breakpoint information filled.
4. Go down and press 'Search' tab twice.
4. Go down to have the hyperlink of the search result.
5. Click the hyperlink.
6. See the FGviewer result for your fusion gene.
FGviewer

check buttonMain function of each fusion partner protein. (from UniProt)
HgeneTgene
.LGR6

Q9HBX8

FUNCTION: Transcriptional activator which is required for calcium-dependent dendritic growth and branching in cortical neurons. Recruits CREB-binding protein (CREBBP) to nuclear bodies. Component of the CREST-BRG1 complex, a multiprotein complex that regulates promoter activation by orchestrating a calcium-dependent release of a repressor complex and a recruitment of an activator complex. In resting neurons, transcription of the c-FOS promoter is inhibited by BRG1-dependent recruitment of a phospho-RB1-HDAC1 repressor complex. Upon calcium influx, RB1 is dephosphorylated by calcineurin, which leads to release of the repressor complex. At the same time, there is increased recruitment of CREBBP to the promoter by a CREST-dependent mechanism, which leads to transcriptional activation. The CREST-BRG1 complex also binds to the NR2B promoter, and activity-dependent induction of NR2B expression involves a release of HDAC1 and recruitment of CREBBP (By similarity). {ECO:0000250}.FUNCTION: Receptor for R-spondins that potentiates the canonical Wnt signaling pathway and acts as a marker of multipotent stem cells in the epidermis. Upon binding to R-spondins (RSPO1, RSPO2, RSPO3 or RSPO4), associates with phosphorylated LRP6 and frizzled receptors that are activated by extracellular Wnt receptors, triggering the canonical Wnt signaling pathway to increase expression of target genes. In contrast to classical G-protein coupled receptors, does not activate heterotrimeric G-proteins to transduce the signal. May act as a tumor suppressor. {ECO:0000269|PubMed:21727895, ECO:0000269|PubMed:22615920}.

check buttonRetention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at

download page


* Minus value of BPloci means that the break pointn is located before the CDS.
- In-frame and retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
HgenePPP1R12Bchr1:202386045chr1:202245434ENST00000356764-2957_86140387.0RepeatNote=ANK 1
HgenePPP1R12Bchr1:202386045chr1:202245434ENST00000356764-2990_119140387.0RepeatNote=ANK 2
HgenePPP1R12Bchr1:202386045chr1:202245434ENST00000480184-21057_86140516.0RepeatNote=ANK 1
HgenePPP1R12Bchr1:202386045chr1:202245434ENST00000480184-21090_119140516.0RepeatNote=ANK 2
TgeneLGR6chr1:202386045chr1:202245434ENST00000255432318952_95590916.0Compositional biasNote=Poly-Gly
TgeneLGR6chr1:202386045chr1:202245434ENST00000367278318952_955142968.0Compositional biasNote=Poly-Gly
TgeneLGR6chr1:202386045chr1:202245434ENST00000439764016952_9550829.0Compositional biasNote=Poly-Gly
TgeneLGR6chr1:202386045chr1:202245434ENST0000043976401626_660829.0DomainNote=LRRNT
TgeneLGR6chr1:202386045chr1:202245434ENST00000255432318115_13690916.0RepeatNote=LRR 2
TgeneLGR6chr1:202386045chr1:202245434ENST00000255432318139_16090916.0RepeatNote=LRR 3
TgeneLGR6chr1:202386045chr1:202245434ENST00000255432318163_18690916.0RepeatNote=LRR 4
TgeneLGR6chr1:202386045chr1:202245434ENST00000255432318187_20890916.0RepeatNote=LRR 5
TgeneLGR6chr1:202386045chr1:202245434ENST00000255432318211_23290916.0RepeatNote=LRR 6
TgeneLGR6chr1:202386045chr1:202245434ENST00000255432318235_25690916.0RepeatNote=LRR 7
TgeneLGR6chr1:202386045chr1:202245434ENST00000255432318258_27990916.0RepeatNote=LRR 8
TgeneLGR6chr1:202386045chr1:202245434ENST00000255432318282_30390916.0RepeatNote=LRR 9
TgeneLGR6chr1:202386045chr1:202245434ENST00000255432318306_32890916.0RepeatNote=LRR 10
TgeneLGR6chr1:202386045chr1:202245434ENST00000255432318329_35090916.0RepeatNote=LRR 11
TgeneLGR6chr1:202386045chr1:202245434ENST00000255432318353_37490916.0RepeatNote=LRR 12
TgeneLGR6chr1:202386045chr1:202245434ENST00000255432318375_39690916.0RepeatNote=LRR 13
TgeneLGR6chr1:202386045chr1:202245434ENST00000255432318399_42090916.0RepeatNote=LRR 14
TgeneLGR6chr1:202386045chr1:202245434ENST00000255432318423_44390916.0RepeatNote=LRR 15
TgeneLGR6chr1:202386045chr1:202245434ENST0000025543231891_11290916.0RepeatNote=LRR 1
TgeneLGR6chr1:202386045chr1:202245434ENST00000367278318163_186142968.0RepeatNote=LRR 4
TgeneLGR6chr1:202386045chr1:202245434ENST00000367278318187_208142968.0RepeatNote=LRR 5
TgeneLGR6chr1:202386045chr1:202245434ENST00000367278318211_232142968.0RepeatNote=LRR 6
TgeneLGR6chr1:202386045chr1:202245434ENST00000367278318235_256142968.0RepeatNote=LRR 7
TgeneLGR6chr1:202386045chr1:202245434ENST00000367278318258_279142968.0RepeatNote=LRR 8
TgeneLGR6chr1:202386045chr1:202245434ENST00000367278318282_303142968.0RepeatNote=LRR 9
TgeneLGR6chr1:202386045chr1:202245434ENST00000367278318306_328142968.0RepeatNote=LRR 10
TgeneLGR6chr1:202386045chr1:202245434ENST00000367278318329_350142968.0RepeatNote=LRR 11
TgeneLGR6chr1:202386045chr1:202245434ENST00000367278318353_374142968.0RepeatNote=LRR 12
TgeneLGR6chr1:202386045chr1:202245434ENST00000367278318375_396142968.0RepeatNote=LRR 13
TgeneLGR6chr1:202386045chr1:202245434ENST00000367278318399_420142968.0RepeatNote=LRR 14
TgeneLGR6chr1:202386045chr1:202245434ENST00000367278318423_443142968.0RepeatNote=LRR 15
TgeneLGR6chr1:202386045chr1:202245434ENST00000439764016115_1360829.0RepeatNote=LRR 2
TgeneLGR6chr1:202386045chr1:202245434ENST00000439764016139_1600829.0RepeatNote=LRR 3
TgeneLGR6chr1:202386045chr1:202245434ENST00000439764016163_1860829.0RepeatNote=LRR 4
TgeneLGR6chr1:202386045chr1:202245434ENST00000439764016187_2080829.0RepeatNote=LRR 5
TgeneLGR6chr1:202386045chr1:202245434ENST00000439764016211_2320829.0RepeatNote=LRR 6
TgeneLGR6chr1:202386045chr1:202245434ENST00000439764016235_2560829.0RepeatNote=LRR 7
TgeneLGR6chr1:202386045chr1:202245434ENST00000439764016258_2790829.0RepeatNote=LRR 8
TgeneLGR6chr1:202386045chr1:202245434ENST00000439764016282_3030829.0RepeatNote=LRR 9
TgeneLGR6chr1:202386045chr1:202245434ENST00000439764016306_3280829.0RepeatNote=LRR 10
TgeneLGR6chr1:202386045chr1:202245434ENST00000439764016329_3500829.0RepeatNote=LRR 11
TgeneLGR6chr1:202386045chr1:202245434ENST00000439764016353_3740829.0RepeatNote=LRR 12
TgeneLGR6chr1:202386045chr1:202245434ENST00000439764016375_3960829.0RepeatNote=LRR 13
TgeneLGR6chr1:202386045chr1:202245434ENST00000439764016399_4200829.0RepeatNote=LRR 14
TgeneLGR6chr1:202386045chr1:202245434ENST00000439764016423_4430829.0RepeatNote=LRR 15
TgeneLGR6chr1:202386045chr1:202245434ENST0000043976401691_1120829.0RepeatNote=LRR 1
TgeneLGR6chr1:202386045chr1:202245434ENST00000255432318589_59890916.0Topological domainCytoplasmic
TgeneLGR6chr1:202386045chr1:202245434ENST00000255432318620_64490916.0Topological domainExtracellular
TgeneLGR6chr1:202386045chr1:202245434ENST00000255432318666_68790916.0Topological domainCytoplasmic
TgeneLGR6chr1:202386045chr1:202245434ENST00000255432318709_72790916.0Topological domainExtracellular
TgeneLGR6chr1:202386045chr1:202245434ENST00000255432318749_77490916.0Topological domainCytoplasmic
TgeneLGR6chr1:202386045chr1:202245434ENST00000255432318796_80990916.0Topological domainExtracellular
TgeneLGR6chr1:202386045chr1:202245434ENST00000255432318831_96790916.0Topological domainCytoplasmic
TgeneLGR6chr1:202386045chr1:202245434ENST00000367278318589_598142968.0Topological domainCytoplasmic
TgeneLGR6chr1:202386045chr1:202245434ENST00000367278318620_644142968.0Topological domainExtracellular
TgeneLGR6chr1:202386045chr1:202245434ENST00000367278318666_687142968.0Topological domainCytoplasmic
TgeneLGR6chr1:202386045chr1:202245434ENST00000367278318709_727142968.0Topological domainExtracellular
TgeneLGR6chr1:202386045chr1:202245434ENST00000367278318749_774142968.0Topological domainCytoplasmic
TgeneLGR6chr1:202386045chr1:202245434ENST00000367278318796_809142968.0Topological domainExtracellular
TgeneLGR6chr1:202386045chr1:202245434ENST00000367278318831_967142968.0Topological domainCytoplasmic
TgeneLGR6chr1:202386045chr1:202245434ENST0000043976401625_5670829.0Topological domainExtracellular
TgeneLGR6chr1:202386045chr1:202245434ENST00000439764016589_5980829.0Topological domainCytoplasmic
TgeneLGR6chr1:202386045chr1:202245434ENST00000439764016620_6440829.0Topological domainExtracellular
TgeneLGR6chr1:202386045chr1:202245434ENST00000439764016666_6870829.0Topological domainCytoplasmic
TgeneLGR6chr1:202386045chr1:202245434ENST00000439764016709_7270829.0Topological domainExtracellular
TgeneLGR6chr1:202386045chr1:202245434ENST00000439764016749_7740829.0Topological domainCytoplasmic
TgeneLGR6chr1:202386045chr1:202245434ENST00000439764016796_8090829.0Topological domainExtracellular
TgeneLGR6chr1:202386045chr1:202245434ENST00000439764016831_9670829.0Topological domainCytoplasmic
TgeneLGR6chr1:202386045chr1:202245434ENST00000255432318568_58890916.0TransmembraneHelical%3B Name%3D1
TgeneLGR6chr1:202386045chr1:202245434ENST00000255432318599_61990916.0TransmembraneHelical%3B Name%3D2
TgeneLGR6chr1:202386045chr1:202245434ENST00000255432318645_66590916.0TransmembraneHelical%3B Name%3D3
TgeneLGR6chr1:202386045chr1:202245434ENST00000255432318688_70890916.0TransmembraneHelical%3B Name%3D4
TgeneLGR6chr1:202386045chr1:202245434ENST00000255432318728_74890916.0TransmembraneHelical%3B Name%3D5
TgeneLGR6chr1:202386045chr1:202245434ENST00000255432318775_79590916.0TransmembraneHelical%3B Name%3D6
TgeneLGR6chr1:202386045chr1:202245434ENST00000255432318810_83090916.0TransmembraneHelical%3B Name%3D7
TgeneLGR6chr1:202386045chr1:202245434ENST00000367278318568_588142968.0TransmembraneHelical%3B Name%3D1
TgeneLGR6chr1:202386045chr1:202245434ENST00000367278318599_619142968.0TransmembraneHelical%3B Name%3D2
TgeneLGR6chr1:202386045chr1:202245434ENST00000367278318645_665142968.0TransmembraneHelical%3B Name%3D3
TgeneLGR6chr1:202386045chr1:202245434ENST00000367278318688_708142968.0TransmembraneHelical%3B Name%3D4
TgeneLGR6chr1:202386045chr1:202245434ENST00000367278318728_748142968.0TransmembraneHelical%3B Name%3D5
TgeneLGR6chr1:202386045chr1:202245434ENST00000367278318775_795142968.0TransmembraneHelical%3B Name%3D6
TgeneLGR6chr1:202386045chr1:202245434ENST00000367278318810_830142968.0TransmembraneHelical%3B Name%3D7
TgeneLGR6chr1:202386045chr1:202245434ENST00000439764016568_5880829.0TransmembraneHelical%3B Name%3D1
TgeneLGR6chr1:202386045chr1:202245434ENST00000439764016599_6190829.0TransmembraneHelical%3B Name%3D2
TgeneLGR6chr1:202386045chr1:202245434ENST00000439764016645_6650829.0TransmembraneHelical%3B Name%3D3
TgeneLGR6chr1:202386045chr1:202245434ENST00000439764016688_7080829.0TransmembraneHelical%3B Name%3D4
TgeneLGR6chr1:202386045chr1:202245434ENST00000439764016728_7480829.0TransmembraneHelical%3B Name%3D5
TgeneLGR6chr1:202386045chr1:202245434ENST00000439764016775_7950829.0TransmembraneHelical%3B Name%3D6
TgeneLGR6chr1:202386045chr1:202245434ENST00000439764016810_8300829.0TransmembraneHelical%3B Name%3D7

- In-frame and not-retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
HgenePPP1R12Bchr1:202386045chr1:202245434ENST00000356764-29336_379140387.0Compositional biasNote=Glu-rich
HgenePPP1R12Bchr1:202386045chr1:202245434ENST00000367270-113336_37902805.3333333333335Compositional biasNote=Glu-rich
HgenePPP1R12Bchr1:202386045chr1:202245434ENST00000391959-112336_3790209.0Compositional biasNote=Glu-rich
HgenePPP1R12Bchr1:202386045chr1:202245434ENST00000480184-210336_379140516.0Compositional biasNote=Glu-rich
HgenePPP1R12Bchr1:202386045chr1:202245434ENST00000356764-29123_152140387.0RepeatNote=ANK 3
HgenePPP1R12Bchr1:202386045chr1:202245434ENST00000356764-29216_245140387.0RepeatNote=ANK 4
HgenePPP1R12Bchr1:202386045chr1:202245434ENST00000356764-29249_278140387.0RepeatNote=ANK 5
HgenePPP1R12Bchr1:202386045chr1:202245434ENST00000367270-113123_15202805.3333333333335RepeatNote=ANK 3
HgenePPP1R12Bchr1:202386045chr1:202245434ENST00000367270-113216_24502805.3333333333335RepeatNote=ANK 4
HgenePPP1R12Bchr1:202386045chr1:202245434ENST00000367270-113249_27802805.3333333333335RepeatNote=ANK 5
HgenePPP1R12Bchr1:202386045chr1:202245434ENST00000367270-11357_8602805.3333333333335RepeatNote=ANK 1
HgenePPP1R12Bchr1:202386045chr1:202245434ENST00000367270-11390_11902805.3333333333335RepeatNote=ANK 2
HgenePPP1R12Bchr1:202386045chr1:202245434ENST00000391959-112123_1520209.0RepeatNote=ANK 3
HgenePPP1R12Bchr1:202386045chr1:202245434ENST00000391959-112216_2450209.0RepeatNote=ANK 4
HgenePPP1R12Bchr1:202386045chr1:202245434ENST00000391959-112249_2780209.0RepeatNote=ANK 5
HgenePPP1R12Bchr1:202386045chr1:202245434ENST00000391959-11257_860209.0RepeatNote=ANK 1
HgenePPP1R12Bchr1:202386045chr1:202245434ENST00000391959-11290_1190209.0RepeatNote=ANK 2
HgenePPP1R12Bchr1:202386045chr1:202245434ENST00000480184-210123_152140516.0RepeatNote=ANK 3
HgenePPP1R12Bchr1:202386045chr1:202245434ENST00000480184-210216_245140516.0RepeatNote=ANK 4
HgenePPP1R12Bchr1:202386045chr1:202245434ENST00000480184-210249_278140516.0RepeatNote=ANK 5
TgeneLGR6chr1:202386045chr1:202245434ENST0000025543231826_6690916.0DomainNote=LRRNT
TgeneLGR6chr1:202386045chr1:202245434ENST0000036727831826_66142968.0DomainNote=LRRNT
TgeneLGR6chr1:202386045chr1:202245434ENST00000367278318115_136142968.0RepeatNote=LRR 2
TgeneLGR6chr1:202386045chr1:202245434ENST00000367278318139_160142968.0RepeatNote=LRR 3
TgeneLGR6chr1:202386045chr1:202245434ENST0000036727831891_112142968.0RepeatNote=LRR 1
TgeneLGR6chr1:202386045chr1:202245434ENST0000025543231825_56790916.0Topological domainExtracellular
TgeneLGR6chr1:202386045chr1:202245434ENST0000036727831825_567142968.0Topological domainExtracellular


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Fusion Gene Sequence for PPP1R12B-LGR6


check button For in-frame fusion transcripts, we provide the fusion transcript sequences and fusion amino acid sequences. To have fusion amino acid sequence, we ran ORFfinder and chose the longest ORF among the all predicted ones.
>67767_67767_1_PPP1R12B-LGR6_PPP1R12B_chr1_202386045_ENST00000336894_LGR6_chr1_202245434_ENST00000255432_length(transcript)=3622nt_BP=572nt
ACTACTGGCGGGAGGAGTAAAGATGGCGGCGCGAGGGTCTCCGCCCTCTGCTCCGGGCTGAAGCGCTCTGAGAGAGGCGGCAGCGGCAAC
TCGAGCCCCAACAGTAATTTAGTGTTGGTAGTTTTGGCAGCAGCTGCCGAGGCCGGAGCAATGGCGGAACTGGAGCACCTAGGAGGGAAG
CGGGCAGAGTCGGCGCGAATGCGGCGGGCAGAGCAGCTTCGGCGCTGGCGGGGCTCGCTGACAGAGCAGGAGCCTGCGGAGCGACGAGGC
GCGGGGCGGCAGCCGCTGACCAGGCGCGGGAGCCCCAGGGTCCGCTTCGAGGACGGTGCTGTCTTTCTGGCCGCCTGCTCTAGCGGGGAC
ACCGACGAGGTGAGAAAGCTTCTGGCAAGAGGTGCTGATATCAACACGGTCAACGTGGACGGCTTGACAGCCCTGCACCAGGCATGTATT
GATGAAAATTTGGACATGGTGAAGTTTCTGGTGGAGAACAGAGCCAATGTAAACCAGCAAGACAACGAGGGCTGGACACCCCTTCATGCA
GCAGCTTCCTGTGGCTATCTCAACATAGCAGAGCGCCTAGATGCCAACCTCATCTCCCTGGTCCCGGAGAGGAGCTTTGAGGGGCTGTCC
TCCCTCCGCCACCTCTGGCTGGACGACAATGCACTCACGGAGATCCCTGTCAGGGCCCTCAACAACCTCCCTGCCCTGCAGGCCATGACC
CTGGCCCTCAACCGCATCAGCCACATCCCCGACTACGCGTTCCAGAATCTCACCAGCCTTGTGGTGCTGCATTTGCATAACAACCGCATC
CAGCATCTGGGGACCCACAGCTTCGAGGGGCTGCACAATCTGGAGACACTAGACCTGAATTATAACAAGCTGCAGGAGTTCCCTGTGGCC
ATCCGGACCCTGGGCAGACTGCAGGAACTGGGGTTCCATAACAACAACATCAAGGCCATCCCAGAAAAGGCCTTCATGGGGAACCCTCTG
CTACAGACGATACACTTTTATGATAACCCAATCCAGTTTGTGGGAAGATCGGCATTCCAGTACCTGCCTAAACTCCACACACTATCTCTG
AATGGTGCCATGGACATCCAGGAGTTTCCAGATCTCAAAGGCACCACCAGCCTGGAGATCCTGACCCTGACCCGCGCAGGCATCCGGCTG
CTCCCATCGGGGATGTGCCAACAGCTGCCCAGGCTCCGAGTCCTGGAACTGTCTCACAATCAAATTGAGGAGCTGCCCAGCCTGCACAGG
TGTCAGAAATTGGAGGAAATCGGCCTCCAACACAACCGCATCTGGGAAATTGGAGCTGACACCTTCAGCCAGCTGAGCTCCCTGCAAGCC
CTGGATCTTAGCTGGAACGCCATCCGGTCCATCCACCCCGAGGCCTTCTCCACCCTGCACTCCCTGGTCAAGCTGGACCTGACAGACAAC
CAGCTGACCACACTGCCCCTGGCTGGACTTGGGGGCTTGATGCATCTGAAGCTCAAAGGGAACCTTGCTCTCTCCCAGGCCTTCTCCAAG
GACAGTTTCCCAAAACTGAGGATCCTGGAGGTGCCTTATGCCTACCAGTGCTGTCCCTATGGGATGTGTGCCAGCTTCTTCAAGGCCTCT
GGGCAGTGGGAGGCTGAAGACCTTCACCTTGATGATGAGGAGTCTTCAAAAAGGCCCCTGGGCCTCCTTGCCAGACAAGCAGAGAACCAC
TATGACCAGGACCTGGATGAGCTCCAGCTGGAGATGGAGGACTCAAAGCCACACCCCAGTGTCCAGTGTAGCCCTACTCCAGGCCCCTTC
AAGCCCTGTGAGTACCTCTTTGAAAGCTGGGGCATCCGCCTGGCCGTGTGGGCCATCGTGTTGCTCTCCGTGCTCTGCAATGGACTGGTG
CTGCTGACCGTGTTCGCTGGCGGGCCTGTCCCCCTGCCCCCGGTCAAGTTTGTGGTAGGTGCGATTGCAGGCGCCAACACCTTGACTGGC
ATTTCCTGTGGCCTTCTAGCCTCAGTCGATGCCCTGACCTTTGGTCAGTTCTCTGAGTACGGAGCCCGCTGGGAGACGGGGCTAGGCTGC
CGGGCCACTGGCTTCCTGGCAGTACTTGGGTCGGAGGCATCGGTGCTGCTGCTCACTCTGGCCGCAGTGCAGTGCAGCGTCTCCGTCTCC
TGTGTCCGGGCCTATGGGAAGTCCCCCTCCCTGGGCAGCGTTCGAGCAGGGGTCCTAGGCTGCCTGGCACTGGCAGGGCTGGCCGCCGCG
CTGCCCCTGGCCTCAGTGGGAGAATACGGGGCCTCCCCACTCTGCCTGCCCTACGCGCCACCTGAGGGTCAGCCAGCAGCCCTGGGCTTC
ACCGTGGCCCTGGTGATGATGAACTCCTTCTGTTTCCTGGTCGTGGCCGGTGCCTACATCAAACTGTACTGTGACCTGCCGCGGGGCGAC
TTTGAGGCCGTGTGGGACTGCGCCATGGTGAGGCACGTGGCCTGGCTCATCTTCGCAGACGGGCTCCTCTACTGTCCCGTGGCCTTCCTC
AGCTTTGCCTCCATGCTGGGCCTCTTCCCTGTCACGCCCGAGGCCGTCAAGTCTGTCCTGCTGGTGGTGCTGCCCCTGCCTGCCTGCCTC
AACCCACTGCTGTACCTGCTCTTCAACCCCCACTTCCGGGATGACCTTCGGCGGCTTCGGCCCCGCGCAGGGGACTCAGGGCCCCTAGCC
TATGCTGCGGCCGGGGAGCTGGAGAAGAGCTCCTGTGATTCTACCCAGGCCCTGGTAGCCTTCTCTGATGTGGATCTCATTCTGGAAGCT
TCTGAAGCTGGGCGGCCCCCTGGGCTGGAGACCTATGGCTTCCCCTCAGTGACCCTCATCTCCTGTCAGCAGCCAGGGGCCCCCAGGCTG
GAGGGCAGCCATTGTGTAGAGCCAGAGGGGAACCACTTTGGGAACCCCCAACCCTCCATGGATGGAGAACTGCTGCTGAGGGCAGAGGGA
TCTACGCCAGCAGGTGGAGGCTTGTCAGGGGGTGGCGGCTTTCAGCCCTCTGGCTTGGCCTTTGCTTCACACGTGTAAATATCCCTCCCC
ATTCTTCTCTTCCCCTCTCTTCCCTTTCCTCTCTCCCCCTCGGTGAATGATGGCTGCTTCTAAAACAAATACAACCAAAACTCAGCAGTG
TGATCTATAGCAGGATGGCCCAGTCCCTGGCTCCACTGATCACCTCTCTCCTGTGACCATCACCAACGGGTGCCTCTTGGCCTGGCTTTC
CCTTGGCCTTCCTCAGCTTCACCTTGATACTGGGCCTCTTCCTTGTCATGTCTGAAGCTGTGGACCAGAGACCTGGACTTTTGTCTGCTT
AAGGGAAATGAGGGAAGTAAAGACAGTGAAGGGGTGGAGGGTTGATCAGGGCACAGTGGACAGGGAGACCTCACAGAGAAAGGCCTGGAA
GGTGATTTCCCGTGTGACTCATGGATAGGATACAAAATGTGTTCCATGTACCATTAATCTTGACATATGCCATGCATAAAGACTTCCTAT
TAAAATAAGCTTTGGAAGAGATTACACATGATGTCTTTTTCTTAGAGATTCACAGTGCATGTTAGTGTAATAAAGAGATAAGTCCTACAG

>67767_67767_1_PPP1R12B-LGR6_PPP1R12B_chr1_202386045_ENST00000336894_LGR6_chr1_202245434_ENST00000255432_length(amino acids)=996AA_BP=172
MKRSERGGSGNSSPNSNLVLVVLAAAAEAGAMAELEHLGGKRAESARMRRAEQLRRWRGSLTEQEPAERRGAGRQPLTRRGSPRVRFEDG
AVFLAACSSGDTDEVRKLLARGADINTVNVDGLTALHQACIDENLDMVKFLVENRANVNQQDNEGWTPLHAAASCGYLNIAERLDANLIS
LVPERSFEGLSSLRHLWLDDNALTEIPVRALNNLPALQAMTLALNRISHIPDYAFQNLTSLVVLHLHNNRIQHLGTHSFEGLHNLETLDL
NYNKLQEFPVAIRTLGRLQELGFHNNNIKAIPEKAFMGNPLLQTIHFYDNPIQFVGRSAFQYLPKLHTLSLNGAMDIQEFPDLKGTTSLE
ILTLTRAGIRLLPSGMCQQLPRLRVLELSHNQIEELPSLHRCQKLEEIGLQHNRIWEIGADTFSQLSSLQALDLSWNAIRSIHPEAFSTL
HSLVKLDLTDNQLTTLPLAGLGGLMHLKLKGNLALSQAFSKDSFPKLRILEVPYAYQCCPYGMCASFFKASGQWEAEDLHLDDEESSKRP
LGLLARQAENHYDQDLDELQLEMEDSKPHPSVQCSPTPGPFKPCEYLFESWGIRLAVWAIVLLSVLCNGLVLLTVFAGGPVPLPPVKFVV
GAIAGANTLTGISCGLLASVDALTFGQFSEYGARWETGLGCRATGFLAVLGSEASVLLLTLAAVQCSVSVSCVRAYGKSPSLGSVRAGVL
GCLALAGLAAALPLASVGEYGASPLCLPYAPPEGQPAALGFTVALVMMNSFCFLVVAGAYIKLYCDLPRGDFEAVWDCAMVRHVAWLIFA
DGLLYCPVAFLSFASMLGLFPVTPEAVKSVLLVVLPLPACLNPLLYLLFNPHFRDDLRRLRPRAGDSGPLAYAAAGELEKSSCDSTQALV
AFSDVDLILEASEAGRPPGLETYGFPSVTLISCQQPGAPRLEGSHCVEPEGNHFGNPQPSMDGELLLRAEGSTPAGGGLSGGGGFQPSGL

--------------------------------------------------------------
>67767_67767_2_PPP1R12B-LGR6_PPP1R12B_chr1_202386045_ENST00000336894_LGR6_chr1_202245434_ENST00000367278_length(transcript)=3622nt_BP=572nt
ACTACTGGCGGGAGGAGTAAAGATGGCGGCGCGAGGGTCTCCGCCCTCTGCTCCGGGCTGAAGCGCTCTGAGAGAGGCGGCAGCGGCAAC
TCGAGCCCCAACAGTAATTTAGTGTTGGTAGTTTTGGCAGCAGCTGCCGAGGCCGGAGCAATGGCGGAACTGGAGCACCTAGGAGGGAAG
CGGGCAGAGTCGGCGCGAATGCGGCGGGCAGAGCAGCTTCGGCGCTGGCGGGGCTCGCTGACAGAGCAGGAGCCTGCGGAGCGACGAGGC
GCGGGGCGGCAGCCGCTGACCAGGCGCGGGAGCCCCAGGGTCCGCTTCGAGGACGGTGCTGTCTTTCTGGCCGCCTGCTCTAGCGGGGAC
ACCGACGAGGTGAGAAAGCTTCTGGCAAGAGGTGCTGATATCAACACGGTCAACGTGGACGGCTTGACAGCCCTGCACCAGGCATGTATT
GATGAAAATTTGGACATGGTGAAGTTTCTGGTGGAGAACAGAGCCAATGTAAACCAGCAAGACAACGAGGGCTGGACACCCCTTCATGCA
GCAGCTTCCTGTGGCTATCTCAACATAGCAGAGCGCCTAGATGCCAACCTCATCTCCCTGGTCCCGGAGAGGAGCTTTGAGGGGCTGTCC
TCCCTCCGCCACCTCTGGCTGGACGACAATGCACTCACGGAGATCCCTGTCAGGGCCCTCAACAACCTCCCTGCCCTGCAGGCCATGACC
CTGGCCCTCAACCGCATCAGCCACATCCCCGACTACGCGTTCCAGAATCTCACCAGCCTTGTGGTGCTGCATTTGCATAACAACCGCATC
CAGCATCTGGGGACCCACAGCTTCGAGGGGCTGCACAATCTGGAGACACTAGACCTGAATTATAACAAGCTGCAGGAGTTCCCTGTGGCC
ATCCGGACCCTGGGCAGACTGCAGGAACTGGGGTTCCATAACAACAACATCAAGGCCATCCCAGAAAAGGCCTTCATGGGGAACCCTCTG
CTACAGACGATACACTTTTATGATAACCCAATCCAGTTTGTGGGAAGATCGGCATTCCAGTACCTGCCTAAACTCCACACACTATCTCTG
AATGGTGCCATGGACATCCAGGAGTTTCCAGATCTCAAAGGCACCACCAGCCTGGAGATCCTGACCCTGACCCGCGCAGGCATCCGGCTG
CTCCCATCGGGGATGTGCCAACAGCTGCCCAGGCTCCGAGTCCTGGAACTGTCTCACAATCAAATTGAGGAGCTGCCCAGCCTGCACAGG
TGTCAGAAATTGGAGGAAATCGGCCTCCAACACAACCGCATCTGGGAAATTGGAGCTGACACCTTCAGCCAGCTGAGCTCCCTGCAAGCC
CTGGATCTTAGCTGGAACGCCATCCGGTCCATCCACCCCGAGGCCTTCTCCACCCTGCACTCCCTGGTCAAGCTGGACCTGACAGACAAC
CAGCTGACCACACTGCCCCTGGCTGGACTTGGGGGCTTGATGCATCTGAAGCTCAAAGGGAACCTTGCTCTCTCCCAGGCCTTCTCCAAG
GACAGTTTCCCAAAACTGAGGATCCTGGAGGTGCCTTATGCCTACCAGTGCTGTCCCTATGGGATGTGTGCCAGCTTCTTCAAGGCCTCT
GGGCAGTGGGAGGCTGAAGACCTTCACCTTGATGATGAGGAGTCTTCAAAAAGGCCCCTGGGCCTCCTTGCCAGACAAGCAGAGAACCAC
TATGACCAGGACCTGGATGAGCTCCAGCTGGAGATGGAGGACTCAAAGCCACACCCCAGTGTCCAGTGTAGCCCTACTCCAGGCCCCTTC
AAGCCCTGTGAGTACCTCTTTGAAAGCTGGGGCATCCGCCTGGCCGTGTGGGCCATCGTGTTGCTCTCCGTGCTCTGCAATGGACTGGTG
CTGCTGACCGTGTTCGCTGGCGGGCCTGTCCCCCTGCCCCCGGTCAAGTTTGTGGTAGGTGCGATTGCAGGCGCCAACACCTTGACTGGC
ATTTCCTGTGGCCTTCTAGCCTCAGTCGATGCCCTGACCTTTGGTCAGTTCTCTGAGTACGGAGCCCGCTGGGAGACGGGGCTAGGCTGC
CGGGCCACTGGCTTCCTGGCAGTACTTGGGTCGGAGGCATCGGTGCTGCTGCTCACTCTGGCCGCAGTGCAGTGCAGCGTCTCCGTCTCC
TGTGTCCGGGCCTATGGGAAGTCCCCCTCCCTGGGCAGCGTTCGAGCAGGGGTCCTAGGCTGCCTGGCACTGGCAGGGCTGGCCGCCGCG
CTGCCCCTGGCCTCAGTGGGAGAATACGGGGCCTCCCCACTCTGCCTGCCCTACGCGCCACCTGAGGGTCAGCCAGCAGCCCTGGGCTTC
ACCGTGGCCCTGGTGATGATGAACTCCTTCTGTTTCCTGGTCGTGGCCGGTGCCTACATCAAACTGTACTGTGACCTGCCGCGGGGCGAC
TTTGAGGCCGTGTGGGACTGCGCCATGGTGAGGCACGTGGCCTGGCTCATCTTCGCAGACGGGCTCCTCTACTGTCCCGTGGCCTTCCTC
AGCTTTGCCTCCATGCTGGGCCTCTTCCCTGTCACGCCCGAGGCCGTCAAGTCTGTCCTGCTGGTGGTGCTGCCCCTGCCTGCCTGCCTC
AACCCACTGCTGTACCTGCTCTTCAACCCCCACTTCCGGGATGACCTTCGGCGGCTTCGGCCCCGCGCAGGGGACTCAGGGCCCCTAGCC
TATGCTGCGGCCGGGGAGCTGGAGAAGAGCTCCTGTGATTCTACCCAGGCCCTGGTAGCCTTCTCTGATGTGGATCTCATTCTGGAAGCT
TCTGAAGCTGGGCGGCCCCCTGGGCTGGAGACCTATGGCTTCCCCTCAGTGACCCTCATCTCCTGTCAGCAGCCAGGGGCCCCCAGGCTG
GAGGGCAGCCATTGTGTAGAGCCAGAGGGGAACCACTTTGGGAACCCCCAACCCTCCATGGATGGAGAACTGCTGCTGAGGGCAGAGGGA
TCTACGCCAGCAGGTGGAGGCTTGTCAGGGGGTGGCGGCTTTCAGCCCTCTGGCTTGGCCTTTGCTTCACACGTGTAAATATCCCTCCCC
ATTCTTCTCTTCCCCTCTCTTCCCTTTCCTCTCTCCCCCTCGGTGAATGATGGCTGCTTCTAAAACAAATACAACCAAAACTCAGCAGTG
TGATCTATAGCAGGATGGCCCAGTCCCTGGCTCCACTGATCACCTCTCTCCTGTGACCATCACCAACGGGTGCCTCTTGGCCTGGCTTTC
CCTTGGCCTTCCTCAGCTTCACCTTGATACTGGGCCTCTTCCTTGTCATGTCTGAAGCTGTGGACCAGAGACCTGGACTTTTGTCTGCTT
AAGGGAAATGAGGGAAGTAAAGACAGTGAAGGGGTGGAGGGTTGATCAGGGCACAGTGGACAGGGAGACCTCACAGAGAAAGGCCTGGAA
GGTGATTTCCCGTGTGACTCATGGATAGGATACAAAATGTGTTCCATGTACCATTAATCTTGACATATGCCATGCATAAAGACTTCCTAT
TAAAATAAGCTTTGGAAGAGATTACACATGATGTCTTTTTCTTAGAGATTCACAGTGCATGTTAGTGTAATAAAGAGATAAGTCCTACAG

>67767_67767_2_PPP1R12B-LGR6_PPP1R12B_chr1_202386045_ENST00000336894_LGR6_chr1_202245434_ENST00000367278_length(amino acids)=996AA_BP=172
MKRSERGGSGNSSPNSNLVLVVLAAAAEAGAMAELEHLGGKRAESARMRRAEQLRRWRGSLTEQEPAERRGAGRQPLTRRGSPRVRFEDG
AVFLAACSSGDTDEVRKLLARGADINTVNVDGLTALHQACIDENLDMVKFLVENRANVNQQDNEGWTPLHAAASCGYLNIAERLDANLIS
LVPERSFEGLSSLRHLWLDDNALTEIPVRALNNLPALQAMTLALNRISHIPDYAFQNLTSLVVLHLHNNRIQHLGTHSFEGLHNLETLDL
NYNKLQEFPVAIRTLGRLQELGFHNNNIKAIPEKAFMGNPLLQTIHFYDNPIQFVGRSAFQYLPKLHTLSLNGAMDIQEFPDLKGTTSLE
ILTLTRAGIRLLPSGMCQQLPRLRVLELSHNQIEELPSLHRCQKLEEIGLQHNRIWEIGADTFSQLSSLQALDLSWNAIRSIHPEAFSTL
HSLVKLDLTDNQLTTLPLAGLGGLMHLKLKGNLALSQAFSKDSFPKLRILEVPYAYQCCPYGMCASFFKASGQWEAEDLHLDDEESSKRP
LGLLARQAENHYDQDLDELQLEMEDSKPHPSVQCSPTPGPFKPCEYLFESWGIRLAVWAIVLLSVLCNGLVLLTVFAGGPVPLPPVKFVV
GAIAGANTLTGISCGLLASVDALTFGQFSEYGARWETGLGCRATGFLAVLGSEASVLLLTLAAVQCSVSVSCVRAYGKSPSLGSVRAGVL
GCLALAGLAAALPLASVGEYGASPLCLPYAPPEGQPAALGFTVALVMMNSFCFLVVAGAYIKLYCDLPRGDFEAVWDCAMVRHVAWLIFA
DGLLYCPVAFLSFASMLGLFPVTPEAVKSVLLVVLPLPACLNPLLYLLFNPHFRDDLRRLRPRAGDSGPLAYAAAGELEKSSCDSTQALV
AFSDVDLILEASEAGRPPGLETYGFPSVTLISCQQPGAPRLEGSHCVEPEGNHFGNPQPSMDGELLLRAEGSTPAGGGLSGGGGFQPSGL

--------------------------------------------------------------
>67767_67767_3_PPP1R12B-LGR6_PPP1R12B_chr1_202386045_ENST00000356764_LGR6_chr1_202245434_ENST00000255432_length(transcript)=3596nt_BP=546nt
CGGCGCGAGGGTCTCCGCCCTCTGCTCCGGGCTGAAGCGCTCTGAGAGAGGCGGCAGCGGCAACTCGAGCCCCAACAGTAATTTAGTGTT
GGTAGTTTTGGCAGCAGCTGCCGAGGCCGGAGCAATGGCGGAACTGGAGCACCTAGGAGGGAAGCGGGCAGAGTCGGCGCGAATGCGGCG
GGCAGAGCAGCTTCGGCGCTGGCGGGGCTCGCTGACAGAGCAGGAGCCTGCGGAGCGACGAGGCGCGGGGCGGCAGCCGCTGACCAGGCG
CGGGAGCCCCAGGGTCCGCTTCGAGGACGGTGCTGTCTTTCTGGCCGCCTGCTCTAGCGGGGACACCGACGAGGTGAGAAAGCTTCTGGC
AAGAGGTGCTGATATCAACACGGTCAACGTGGACGGCTTGACAGCCCTGCACCAGGCATGTATTGATGAAAATTTGGACATGGTGAAGTT
TCTGGTGGAGAACAGAGCCAATGTAAACCAGCAAGACAACGAGGGCTGGACACCCCTTCATGCAGCAGCTTCCTGTGGCTATCTCAACAT
AGCAGAGCGCCTAGATGCCAACCTCATCTCCCTGGTCCCGGAGAGGAGCTTTGAGGGGCTGTCCTCCCTCCGCCACCTCTGGCTGGACGA
CAATGCACTCACGGAGATCCCTGTCAGGGCCCTCAACAACCTCCCTGCCCTGCAGGCCATGACCCTGGCCCTCAACCGCATCAGCCACAT
CCCCGACTACGCGTTCCAGAATCTCACCAGCCTTGTGGTGCTGCATTTGCATAACAACCGCATCCAGCATCTGGGGACCCACAGCTTCGA
GGGGCTGCACAATCTGGAGACACTAGACCTGAATTATAACAAGCTGCAGGAGTTCCCTGTGGCCATCCGGACCCTGGGCAGACTGCAGGA
ACTGGGGTTCCATAACAACAACATCAAGGCCATCCCAGAAAAGGCCTTCATGGGGAACCCTCTGCTACAGACGATACACTTTTATGATAA
CCCAATCCAGTTTGTGGGAAGATCGGCATTCCAGTACCTGCCTAAACTCCACACACTATCTCTGAATGGTGCCATGGACATCCAGGAGTT
TCCAGATCTCAAAGGCACCACCAGCCTGGAGATCCTGACCCTGACCCGCGCAGGCATCCGGCTGCTCCCATCGGGGATGTGCCAACAGCT
GCCCAGGCTCCGAGTCCTGGAACTGTCTCACAATCAAATTGAGGAGCTGCCCAGCCTGCACAGGTGTCAGAAATTGGAGGAAATCGGCCT
CCAACACAACCGCATCTGGGAAATTGGAGCTGACACCTTCAGCCAGCTGAGCTCCCTGCAAGCCCTGGATCTTAGCTGGAACGCCATCCG
GTCCATCCACCCCGAGGCCTTCTCCACCCTGCACTCCCTGGTCAAGCTGGACCTGACAGACAACCAGCTGACCACACTGCCCCTGGCTGG
ACTTGGGGGCTTGATGCATCTGAAGCTCAAAGGGAACCTTGCTCTCTCCCAGGCCTTCTCCAAGGACAGTTTCCCAAAACTGAGGATCCT
GGAGGTGCCTTATGCCTACCAGTGCTGTCCCTATGGGATGTGTGCCAGCTTCTTCAAGGCCTCTGGGCAGTGGGAGGCTGAAGACCTTCA
CCTTGATGATGAGGAGTCTTCAAAAAGGCCCCTGGGCCTCCTTGCCAGACAAGCAGAGAACCACTATGACCAGGACCTGGATGAGCTCCA
GCTGGAGATGGAGGACTCAAAGCCACACCCCAGTGTCCAGTGTAGCCCTACTCCAGGCCCCTTCAAGCCCTGTGAGTACCTCTTTGAAAG
CTGGGGCATCCGCCTGGCCGTGTGGGCCATCGTGTTGCTCTCCGTGCTCTGCAATGGACTGGTGCTGCTGACCGTGTTCGCTGGCGGGCC
TGTCCCCCTGCCCCCGGTCAAGTTTGTGGTAGGTGCGATTGCAGGCGCCAACACCTTGACTGGCATTTCCTGTGGCCTTCTAGCCTCAGT
CGATGCCCTGACCTTTGGTCAGTTCTCTGAGTACGGAGCCCGCTGGGAGACGGGGCTAGGCTGCCGGGCCACTGGCTTCCTGGCAGTACT
TGGGTCGGAGGCATCGGTGCTGCTGCTCACTCTGGCCGCAGTGCAGTGCAGCGTCTCCGTCTCCTGTGTCCGGGCCTATGGGAAGTCCCC
CTCCCTGGGCAGCGTTCGAGCAGGGGTCCTAGGCTGCCTGGCACTGGCAGGGCTGGCCGCCGCGCTGCCCCTGGCCTCAGTGGGAGAATA
CGGGGCCTCCCCACTCTGCCTGCCCTACGCGCCACCTGAGGGTCAGCCAGCAGCCCTGGGCTTCACCGTGGCCCTGGTGATGATGAACTC
CTTCTGTTTCCTGGTCGTGGCCGGTGCCTACATCAAACTGTACTGTGACCTGCCGCGGGGCGACTTTGAGGCCGTGTGGGACTGCGCCAT
GGTGAGGCACGTGGCCTGGCTCATCTTCGCAGACGGGCTCCTCTACTGTCCCGTGGCCTTCCTCAGCTTTGCCTCCATGCTGGGCCTCTT
CCCTGTCACGCCCGAGGCCGTCAAGTCTGTCCTGCTGGTGGTGCTGCCCCTGCCTGCCTGCCTCAACCCACTGCTGTACCTGCTCTTCAA
CCCCCACTTCCGGGATGACCTTCGGCGGCTTCGGCCCCGCGCAGGGGACTCAGGGCCCCTAGCCTATGCTGCGGCCGGGGAGCTGGAGAA
GAGCTCCTGTGATTCTACCCAGGCCCTGGTAGCCTTCTCTGATGTGGATCTCATTCTGGAAGCTTCTGAAGCTGGGCGGCCCCCTGGGCT
GGAGACCTATGGCTTCCCCTCAGTGACCCTCATCTCCTGTCAGCAGCCAGGGGCCCCCAGGCTGGAGGGCAGCCATTGTGTAGAGCCAGA
GGGGAACCACTTTGGGAACCCCCAACCCTCCATGGATGGAGAACTGCTGCTGAGGGCAGAGGGATCTACGCCAGCAGGTGGAGGCTTGTC
AGGGGGTGGCGGCTTTCAGCCCTCTGGCTTGGCCTTTGCTTCACACGTGTAAATATCCCTCCCCATTCTTCTCTTCCCCTCTCTTCCCTT
TCCTCTCTCCCCCTCGGTGAATGATGGCTGCTTCTAAAACAAATACAACCAAAACTCAGCAGTGTGATCTATAGCAGGATGGCCCAGTCC
CTGGCTCCACTGATCACCTCTCTCCTGTGACCATCACCAACGGGTGCCTCTTGGCCTGGCTTTCCCTTGGCCTTCCTCAGCTTCACCTTG
ATACTGGGCCTCTTCCTTGTCATGTCTGAAGCTGTGGACCAGAGACCTGGACTTTTGTCTGCTTAAGGGAAATGAGGGAAGTAAAGACAG
TGAAGGGGTGGAGGGTTGATCAGGGCACAGTGGACAGGGAGACCTCACAGAGAAAGGCCTGGAAGGTGATTTCCCGTGTGACTCATGGAT
AGGATACAAAATGTGTTCCATGTACCATTAATCTTGACATATGCCATGCATAAAGACTTCCTATTAAAATAAGCTTTGGAAGAGATTACA

>67767_67767_3_PPP1R12B-LGR6_PPP1R12B_chr1_202386045_ENST00000356764_LGR6_chr1_202245434_ENST00000255432_length(amino acids)=996AA_BP=172
MKRSERGGSGNSSPNSNLVLVVLAAAAEAGAMAELEHLGGKRAESARMRRAEQLRRWRGSLTEQEPAERRGAGRQPLTRRGSPRVRFEDG
AVFLAACSSGDTDEVRKLLARGADINTVNVDGLTALHQACIDENLDMVKFLVENRANVNQQDNEGWTPLHAAASCGYLNIAERLDANLIS
LVPERSFEGLSSLRHLWLDDNALTEIPVRALNNLPALQAMTLALNRISHIPDYAFQNLTSLVVLHLHNNRIQHLGTHSFEGLHNLETLDL
NYNKLQEFPVAIRTLGRLQELGFHNNNIKAIPEKAFMGNPLLQTIHFYDNPIQFVGRSAFQYLPKLHTLSLNGAMDIQEFPDLKGTTSLE
ILTLTRAGIRLLPSGMCQQLPRLRVLELSHNQIEELPSLHRCQKLEEIGLQHNRIWEIGADTFSQLSSLQALDLSWNAIRSIHPEAFSTL
HSLVKLDLTDNQLTTLPLAGLGGLMHLKLKGNLALSQAFSKDSFPKLRILEVPYAYQCCPYGMCASFFKASGQWEAEDLHLDDEESSKRP
LGLLARQAENHYDQDLDELQLEMEDSKPHPSVQCSPTPGPFKPCEYLFESWGIRLAVWAIVLLSVLCNGLVLLTVFAGGPVPLPPVKFVV
GAIAGANTLTGISCGLLASVDALTFGQFSEYGARWETGLGCRATGFLAVLGSEASVLLLTLAAVQCSVSVSCVRAYGKSPSLGSVRAGVL
GCLALAGLAAALPLASVGEYGASPLCLPYAPPEGQPAALGFTVALVMMNSFCFLVVAGAYIKLYCDLPRGDFEAVWDCAMVRHVAWLIFA
DGLLYCPVAFLSFASMLGLFPVTPEAVKSVLLVVLPLPACLNPLLYLLFNPHFRDDLRRLRPRAGDSGPLAYAAAGELEKSSCDSTQALV
AFSDVDLILEASEAGRPPGLETYGFPSVTLISCQQPGAPRLEGSHCVEPEGNHFGNPQPSMDGELLLRAEGSTPAGGGLSGGGGFQPSGL

--------------------------------------------------------------
>67767_67767_4_PPP1R12B-LGR6_PPP1R12B_chr1_202386045_ENST00000356764_LGR6_chr1_202245434_ENST00000367278_length(transcript)=3596nt_BP=546nt
CGGCGCGAGGGTCTCCGCCCTCTGCTCCGGGCTGAAGCGCTCTGAGAGAGGCGGCAGCGGCAACTCGAGCCCCAACAGTAATTTAGTGTT
GGTAGTTTTGGCAGCAGCTGCCGAGGCCGGAGCAATGGCGGAACTGGAGCACCTAGGAGGGAAGCGGGCAGAGTCGGCGCGAATGCGGCG
GGCAGAGCAGCTTCGGCGCTGGCGGGGCTCGCTGACAGAGCAGGAGCCTGCGGAGCGACGAGGCGCGGGGCGGCAGCCGCTGACCAGGCG
CGGGAGCCCCAGGGTCCGCTTCGAGGACGGTGCTGTCTTTCTGGCCGCCTGCTCTAGCGGGGACACCGACGAGGTGAGAAAGCTTCTGGC
AAGAGGTGCTGATATCAACACGGTCAACGTGGACGGCTTGACAGCCCTGCACCAGGCATGTATTGATGAAAATTTGGACATGGTGAAGTT
TCTGGTGGAGAACAGAGCCAATGTAAACCAGCAAGACAACGAGGGCTGGACACCCCTTCATGCAGCAGCTTCCTGTGGCTATCTCAACAT
AGCAGAGCGCCTAGATGCCAACCTCATCTCCCTGGTCCCGGAGAGGAGCTTTGAGGGGCTGTCCTCCCTCCGCCACCTCTGGCTGGACGA
CAATGCACTCACGGAGATCCCTGTCAGGGCCCTCAACAACCTCCCTGCCCTGCAGGCCATGACCCTGGCCCTCAACCGCATCAGCCACAT
CCCCGACTACGCGTTCCAGAATCTCACCAGCCTTGTGGTGCTGCATTTGCATAACAACCGCATCCAGCATCTGGGGACCCACAGCTTCGA
GGGGCTGCACAATCTGGAGACACTAGACCTGAATTATAACAAGCTGCAGGAGTTCCCTGTGGCCATCCGGACCCTGGGCAGACTGCAGGA
ACTGGGGTTCCATAACAACAACATCAAGGCCATCCCAGAAAAGGCCTTCATGGGGAACCCTCTGCTACAGACGATACACTTTTATGATAA
CCCAATCCAGTTTGTGGGAAGATCGGCATTCCAGTACCTGCCTAAACTCCACACACTATCTCTGAATGGTGCCATGGACATCCAGGAGTT
TCCAGATCTCAAAGGCACCACCAGCCTGGAGATCCTGACCCTGACCCGCGCAGGCATCCGGCTGCTCCCATCGGGGATGTGCCAACAGCT
GCCCAGGCTCCGAGTCCTGGAACTGTCTCACAATCAAATTGAGGAGCTGCCCAGCCTGCACAGGTGTCAGAAATTGGAGGAAATCGGCCT
CCAACACAACCGCATCTGGGAAATTGGAGCTGACACCTTCAGCCAGCTGAGCTCCCTGCAAGCCCTGGATCTTAGCTGGAACGCCATCCG
GTCCATCCACCCCGAGGCCTTCTCCACCCTGCACTCCCTGGTCAAGCTGGACCTGACAGACAACCAGCTGACCACACTGCCCCTGGCTGG
ACTTGGGGGCTTGATGCATCTGAAGCTCAAAGGGAACCTTGCTCTCTCCCAGGCCTTCTCCAAGGACAGTTTCCCAAAACTGAGGATCCT
GGAGGTGCCTTATGCCTACCAGTGCTGTCCCTATGGGATGTGTGCCAGCTTCTTCAAGGCCTCTGGGCAGTGGGAGGCTGAAGACCTTCA
CCTTGATGATGAGGAGTCTTCAAAAAGGCCCCTGGGCCTCCTTGCCAGACAAGCAGAGAACCACTATGACCAGGACCTGGATGAGCTCCA
GCTGGAGATGGAGGACTCAAAGCCACACCCCAGTGTCCAGTGTAGCCCTACTCCAGGCCCCTTCAAGCCCTGTGAGTACCTCTTTGAAAG
CTGGGGCATCCGCCTGGCCGTGTGGGCCATCGTGTTGCTCTCCGTGCTCTGCAATGGACTGGTGCTGCTGACCGTGTTCGCTGGCGGGCC
TGTCCCCCTGCCCCCGGTCAAGTTTGTGGTAGGTGCGATTGCAGGCGCCAACACCTTGACTGGCATTTCCTGTGGCCTTCTAGCCTCAGT
CGATGCCCTGACCTTTGGTCAGTTCTCTGAGTACGGAGCCCGCTGGGAGACGGGGCTAGGCTGCCGGGCCACTGGCTTCCTGGCAGTACT
TGGGTCGGAGGCATCGGTGCTGCTGCTCACTCTGGCCGCAGTGCAGTGCAGCGTCTCCGTCTCCTGTGTCCGGGCCTATGGGAAGTCCCC
CTCCCTGGGCAGCGTTCGAGCAGGGGTCCTAGGCTGCCTGGCACTGGCAGGGCTGGCCGCCGCGCTGCCCCTGGCCTCAGTGGGAGAATA
CGGGGCCTCCCCACTCTGCCTGCCCTACGCGCCACCTGAGGGTCAGCCAGCAGCCCTGGGCTTCACCGTGGCCCTGGTGATGATGAACTC
CTTCTGTTTCCTGGTCGTGGCCGGTGCCTACATCAAACTGTACTGTGACCTGCCGCGGGGCGACTTTGAGGCCGTGTGGGACTGCGCCAT
GGTGAGGCACGTGGCCTGGCTCATCTTCGCAGACGGGCTCCTCTACTGTCCCGTGGCCTTCCTCAGCTTTGCCTCCATGCTGGGCCTCTT
CCCTGTCACGCCCGAGGCCGTCAAGTCTGTCCTGCTGGTGGTGCTGCCCCTGCCTGCCTGCCTCAACCCACTGCTGTACCTGCTCTTCAA
CCCCCACTTCCGGGATGACCTTCGGCGGCTTCGGCCCCGCGCAGGGGACTCAGGGCCCCTAGCCTATGCTGCGGCCGGGGAGCTGGAGAA
GAGCTCCTGTGATTCTACCCAGGCCCTGGTAGCCTTCTCTGATGTGGATCTCATTCTGGAAGCTTCTGAAGCTGGGCGGCCCCCTGGGCT
GGAGACCTATGGCTTCCCCTCAGTGACCCTCATCTCCTGTCAGCAGCCAGGGGCCCCCAGGCTGGAGGGCAGCCATTGTGTAGAGCCAGA
GGGGAACCACTTTGGGAACCCCCAACCCTCCATGGATGGAGAACTGCTGCTGAGGGCAGAGGGATCTACGCCAGCAGGTGGAGGCTTGTC
AGGGGGTGGCGGCTTTCAGCCCTCTGGCTTGGCCTTTGCTTCACACGTGTAAATATCCCTCCCCATTCTTCTCTTCCCCTCTCTTCCCTT
TCCTCTCTCCCCCTCGGTGAATGATGGCTGCTTCTAAAACAAATACAACCAAAACTCAGCAGTGTGATCTATAGCAGGATGGCCCAGTCC
CTGGCTCCACTGATCACCTCTCTCCTGTGACCATCACCAACGGGTGCCTCTTGGCCTGGCTTTCCCTTGGCCTTCCTCAGCTTCACCTTG
ATACTGGGCCTCTTCCTTGTCATGTCTGAAGCTGTGGACCAGAGACCTGGACTTTTGTCTGCTTAAGGGAAATGAGGGAAGTAAAGACAG
TGAAGGGGTGGAGGGTTGATCAGGGCACAGTGGACAGGGAGACCTCACAGAGAAAGGCCTGGAAGGTGATTTCCCGTGTGACTCATGGAT
AGGATACAAAATGTGTTCCATGTACCATTAATCTTGACATATGCCATGCATAAAGACTTCCTATTAAAATAAGCTTTGGAAGAGATTACA

>67767_67767_4_PPP1R12B-LGR6_PPP1R12B_chr1_202386045_ENST00000356764_LGR6_chr1_202245434_ENST00000367278_length(amino acids)=996AA_BP=172
MKRSERGGSGNSSPNSNLVLVVLAAAAEAGAMAELEHLGGKRAESARMRRAEQLRRWRGSLTEQEPAERRGAGRQPLTRRGSPRVRFEDG
AVFLAACSSGDTDEVRKLLARGADINTVNVDGLTALHQACIDENLDMVKFLVENRANVNQQDNEGWTPLHAAASCGYLNIAERLDANLIS
LVPERSFEGLSSLRHLWLDDNALTEIPVRALNNLPALQAMTLALNRISHIPDYAFQNLTSLVVLHLHNNRIQHLGTHSFEGLHNLETLDL
NYNKLQEFPVAIRTLGRLQELGFHNNNIKAIPEKAFMGNPLLQTIHFYDNPIQFVGRSAFQYLPKLHTLSLNGAMDIQEFPDLKGTTSLE
ILTLTRAGIRLLPSGMCQQLPRLRVLELSHNQIEELPSLHRCQKLEEIGLQHNRIWEIGADTFSQLSSLQALDLSWNAIRSIHPEAFSTL
HSLVKLDLTDNQLTTLPLAGLGGLMHLKLKGNLALSQAFSKDSFPKLRILEVPYAYQCCPYGMCASFFKASGQWEAEDLHLDDEESSKRP
LGLLARQAENHYDQDLDELQLEMEDSKPHPSVQCSPTPGPFKPCEYLFESWGIRLAVWAIVLLSVLCNGLVLLTVFAGGPVPLPPVKFVV
GAIAGANTLTGISCGLLASVDALTFGQFSEYGARWETGLGCRATGFLAVLGSEASVLLLTLAAVQCSVSVSCVRAYGKSPSLGSVRAGVL
GCLALAGLAAALPLASVGEYGASPLCLPYAPPEGQPAALGFTVALVMMNSFCFLVVAGAYIKLYCDLPRGDFEAVWDCAMVRHVAWLIFA
DGLLYCPVAFLSFASMLGLFPVTPEAVKSVLLVVLPLPACLNPLLYLLFNPHFRDDLRRLRPRAGDSGPLAYAAAGELEKSSCDSTQALV
AFSDVDLILEASEAGRPPGLETYGFPSVTLISCQQPGAPRLEGSHCVEPEGNHFGNPQPSMDGELLLRAEGSTPAGGGLSGGGGFQPSGL

--------------------------------------------------------------
>67767_67767_5_PPP1R12B-LGR6_PPP1R12B_chr1_202386045_ENST00000480184_LGR6_chr1_202245434_ENST00000255432_length(transcript)=3604nt_BP=554nt
AAAGATGGCGGCGCGAGGGTCTCCGCCCTCTGCTCCGGGCTGAAGCGCTCTGAGAGAGGCGGCAGCGGCAACTCGAGCCCCAACAGTAAT
TTAGTGTTGGTAGTTTTGGCAGCAGCTGCCGAGGCCGGAGCAATGGCGGAACTGGAGCACCTAGGAGGGAAGCGGGCAGAGTCGGCGCGA
ATGCGGCGGGCAGAGCAGCTTCGGCGCTGGCGGGGCTCGCTGACAGAGCAGGAGCCTGCGGAGCGACGAGGCGCGGGGCGGCAGCCGCTG
ACCAGGCGCGGGAGCCCCAGGGTCCGCTTCGAGGACGGTGCTGTCTTTCTGGCCGCCTGCTCTAGCGGGGACACCGACGAGGTGAGAAAG
CTTCTGGCAAGAGGTGCTGATATCAACACGGTCAACGTGGACGGCTTGACAGCCCTGCACCAGGCATGTATTGATGAAAATTTGGACATG
GTGAAGTTTCTGGTGGAGAACAGAGCCAATGTAAACCAGCAAGACAACGAGGGCTGGACACCCCTTCATGCAGCAGCTTCCTGTGGCTAT
CTCAACATAGCAGAGCGCCTAGATGCCAACCTCATCTCCCTGGTCCCGGAGAGGAGCTTTGAGGGGCTGTCCTCCCTCCGCCACCTCTGG
CTGGACGACAATGCACTCACGGAGATCCCTGTCAGGGCCCTCAACAACCTCCCTGCCCTGCAGGCCATGACCCTGGCCCTCAACCGCATC
AGCCACATCCCCGACTACGCGTTCCAGAATCTCACCAGCCTTGTGGTGCTGCATTTGCATAACAACCGCATCCAGCATCTGGGGACCCAC
AGCTTCGAGGGGCTGCACAATCTGGAGACACTAGACCTGAATTATAACAAGCTGCAGGAGTTCCCTGTGGCCATCCGGACCCTGGGCAGA
CTGCAGGAACTGGGGTTCCATAACAACAACATCAAGGCCATCCCAGAAAAGGCCTTCATGGGGAACCCTCTGCTACAGACGATACACTTT
TATGATAACCCAATCCAGTTTGTGGGAAGATCGGCATTCCAGTACCTGCCTAAACTCCACACACTATCTCTGAATGGTGCCATGGACATC
CAGGAGTTTCCAGATCTCAAAGGCACCACCAGCCTGGAGATCCTGACCCTGACCCGCGCAGGCATCCGGCTGCTCCCATCGGGGATGTGC
CAACAGCTGCCCAGGCTCCGAGTCCTGGAACTGTCTCACAATCAAATTGAGGAGCTGCCCAGCCTGCACAGGTGTCAGAAATTGGAGGAA
ATCGGCCTCCAACACAACCGCATCTGGGAAATTGGAGCTGACACCTTCAGCCAGCTGAGCTCCCTGCAAGCCCTGGATCTTAGCTGGAAC
GCCATCCGGTCCATCCACCCCGAGGCCTTCTCCACCCTGCACTCCCTGGTCAAGCTGGACCTGACAGACAACCAGCTGACCACACTGCCC
CTGGCTGGACTTGGGGGCTTGATGCATCTGAAGCTCAAAGGGAACCTTGCTCTCTCCCAGGCCTTCTCCAAGGACAGTTTCCCAAAACTG
AGGATCCTGGAGGTGCCTTATGCCTACCAGTGCTGTCCCTATGGGATGTGTGCCAGCTTCTTCAAGGCCTCTGGGCAGTGGGAGGCTGAA
GACCTTCACCTTGATGATGAGGAGTCTTCAAAAAGGCCCCTGGGCCTCCTTGCCAGACAAGCAGAGAACCACTATGACCAGGACCTGGAT
GAGCTCCAGCTGGAGATGGAGGACTCAAAGCCACACCCCAGTGTCCAGTGTAGCCCTACTCCAGGCCCCTTCAAGCCCTGTGAGTACCTC
TTTGAAAGCTGGGGCATCCGCCTGGCCGTGTGGGCCATCGTGTTGCTCTCCGTGCTCTGCAATGGACTGGTGCTGCTGACCGTGTTCGCT
GGCGGGCCTGTCCCCCTGCCCCCGGTCAAGTTTGTGGTAGGTGCGATTGCAGGCGCCAACACCTTGACTGGCATTTCCTGTGGCCTTCTA
GCCTCAGTCGATGCCCTGACCTTTGGTCAGTTCTCTGAGTACGGAGCCCGCTGGGAGACGGGGCTAGGCTGCCGGGCCACTGGCTTCCTG
GCAGTACTTGGGTCGGAGGCATCGGTGCTGCTGCTCACTCTGGCCGCAGTGCAGTGCAGCGTCTCCGTCTCCTGTGTCCGGGCCTATGGG
AAGTCCCCCTCCCTGGGCAGCGTTCGAGCAGGGGTCCTAGGCTGCCTGGCACTGGCAGGGCTGGCCGCCGCGCTGCCCCTGGCCTCAGTG
GGAGAATACGGGGCCTCCCCACTCTGCCTGCCCTACGCGCCACCTGAGGGTCAGCCAGCAGCCCTGGGCTTCACCGTGGCCCTGGTGATG
ATGAACTCCTTCTGTTTCCTGGTCGTGGCCGGTGCCTACATCAAACTGTACTGTGACCTGCCGCGGGGCGACTTTGAGGCCGTGTGGGAC
TGCGCCATGGTGAGGCACGTGGCCTGGCTCATCTTCGCAGACGGGCTCCTCTACTGTCCCGTGGCCTTCCTCAGCTTTGCCTCCATGCTG
GGCCTCTTCCCTGTCACGCCCGAGGCCGTCAAGTCTGTCCTGCTGGTGGTGCTGCCCCTGCCTGCCTGCCTCAACCCACTGCTGTACCTG
CTCTTCAACCCCCACTTCCGGGATGACCTTCGGCGGCTTCGGCCCCGCGCAGGGGACTCAGGGCCCCTAGCCTATGCTGCGGCCGGGGAG
CTGGAGAAGAGCTCCTGTGATTCTACCCAGGCCCTGGTAGCCTTCTCTGATGTGGATCTCATTCTGGAAGCTTCTGAAGCTGGGCGGCCC
CCTGGGCTGGAGACCTATGGCTTCCCCTCAGTGACCCTCATCTCCTGTCAGCAGCCAGGGGCCCCCAGGCTGGAGGGCAGCCATTGTGTA
GAGCCAGAGGGGAACCACTTTGGGAACCCCCAACCCTCCATGGATGGAGAACTGCTGCTGAGGGCAGAGGGATCTACGCCAGCAGGTGGA
GGCTTGTCAGGGGGTGGCGGCTTTCAGCCCTCTGGCTTGGCCTTTGCTTCACACGTGTAAATATCCCTCCCCATTCTTCTCTTCCCCTCT
CTTCCCTTTCCTCTCTCCCCCTCGGTGAATGATGGCTGCTTCTAAAACAAATACAACCAAAACTCAGCAGTGTGATCTATAGCAGGATGG
CCCAGTCCCTGGCTCCACTGATCACCTCTCTCCTGTGACCATCACCAACGGGTGCCTCTTGGCCTGGCTTTCCCTTGGCCTTCCTCAGCT
TCACCTTGATACTGGGCCTCTTCCTTGTCATGTCTGAAGCTGTGGACCAGAGACCTGGACTTTTGTCTGCTTAAGGGAAATGAGGGAAGT
AAAGACAGTGAAGGGGTGGAGGGTTGATCAGGGCACAGTGGACAGGGAGACCTCACAGAGAAAGGCCTGGAAGGTGATTTCCCGTGTGAC
TCATGGATAGGATACAAAATGTGTTCCATGTACCATTAATCTTGACATATGCCATGCATAAAGACTTCCTATTAAAATAAGCTTTGGAAG
AGATTACACATGATGTCTTTTTCTTAGAGATTCACAGTGCATGTTAGTGTAATAAAGAGATAAGTCCTACAGTAGTAAAATCTATTGAAC

>67767_67767_5_PPP1R12B-LGR6_PPP1R12B_chr1_202386045_ENST00000480184_LGR6_chr1_202245434_ENST00000255432_length(amino acids)=996AA_BP=172
MKRSERGGSGNSSPNSNLVLVVLAAAAEAGAMAELEHLGGKRAESARMRRAEQLRRWRGSLTEQEPAERRGAGRQPLTRRGSPRVRFEDG
AVFLAACSSGDTDEVRKLLARGADINTVNVDGLTALHQACIDENLDMVKFLVENRANVNQQDNEGWTPLHAAASCGYLNIAERLDANLIS
LVPERSFEGLSSLRHLWLDDNALTEIPVRALNNLPALQAMTLALNRISHIPDYAFQNLTSLVVLHLHNNRIQHLGTHSFEGLHNLETLDL
NYNKLQEFPVAIRTLGRLQELGFHNNNIKAIPEKAFMGNPLLQTIHFYDNPIQFVGRSAFQYLPKLHTLSLNGAMDIQEFPDLKGTTSLE
ILTLTRAGIRLLPSGMCQQLPRLRVLELSHNQIEELPSLHRCQKLEEIGLQHNRIWEIGADTFSQLSSLQALDLSWNAIRSIHPEAFSTL
HSLVKLDLTDNQLTTLPLAGLGGLMHLKLKGNLALSQAFSKDSFPKLRILEVPYAYQCCPYGMCASFFKASGQWEAEDLHLDDEESSKRP
LGLLARQAENHYDQDLDELQLEMEDSKPHPSVQCSPTPGPFKPCEYLFESWGIRLAVWAIVLLSVLCNGLVLLTVFAGGPVPLPPVKFVV
GAIAGANTLTGISCGLLASVDALTFGQFSEYGARWETGLGCRATGFLAVLGSEASVLLLTLAAVQCSVSVSCVRAYGKSPSLGSVRAGVL
GCLALAGLAAALPLASVGEYGASPLCLPYAPPEGQPAALGFTVALVMMNSFCFLVVAGAYIKLYCDLPRGDFEAVWDCAMVRHVAWLIFA
DGLLYCPVAFLSFASMLGLFPVTPEAVKSVLLVVLPLPACLNPLLYLLFNPHFRDDLRRLRPRAGDSGPLAYAAAGELEKSSCDSTQALV
AFSDVDLILEASEAGRPPGLETYGFPSVTLISCQQPGAPRLEGSHCVEPEGNHFGNPQPSMDGELLLRAEGSTPAGGGLSGGGGFQPSGL

--------------------------------------------------------------
>67767_67767_6_PPP1R12B-LGR6_PPP1R12B_chr1_202386045_ENST00000480184_LGR6_chr1_202245434_ENST00000367278_length(transcript)=3604nt_BP=554nt
AAAGATGGCGGCGCGAGGGTCTCCGCCCTCTGCTCCGGGCTGAAGCGCTCTGAGAGAGGCGGCAGCGGCAACTCGAGCCCCAACAGTAAT
TTAGTGTTGGTAGTTTTGGCAGCAGCTGCCGAGGCCGGAGCAATGGCGGAACTGGAGCACCTAGGAGGGAAGCGGGCAGAGTCGGCGCGA
ATGCGGCGGGCAGAGCAGCTTCGGCGCTGGCGGGGCTCGCTGACAGAGCAGGAGCCTGCGGAGCGACGAGGCGCGGGGCGGCAGCCGCTG
ACCAGGCGCGGGAGCCCCAGGGTCCGCTTCGAGGACGGTGCTGTCTTTCTGGCCGCCTGCTCTAGCGGGGACACCGACGAGGTGAGAAAG
CTTCTGGCAAGAGGTGCTGATATCAACACGGTCAACGTGGACGGCTTGACAGCCCTGCACCAGGCATGTATTGATGAAAATTTGGACATG
GTGAAGTTTCTGGTGGAGAACAGAGCCAATGTAAACCAGCAAGACAACGAGGGCTGGACACCCCTTCATGCAGCAGCTTCCTGTGGCTAT
CTCAACATAGCAGAGCGCCTAGATGCCAACCTCATCTCCCTGGTCCCGGAGAGGAGCTTTGAGGGGCTGTCCTCCCTCCGCCACCTCTGG
CTGGACGACAATGCACTCACGGAGATCCCTGTCAGGGCCCTCAACAACCTCCCTGCCCTGCAGGCCATGACCCTGGCCCTCAACCGCATC
AGCCACATCCCCGACTACGCGTTCCAGAATCTCACCAGCCTTGTGGTGCTGCATTTGCATAACAACCGCATCCAGCATCTGGGGACCCAC
AGCTTCGAGGGGCTGCACAATCTGGAGACACTAGACCTGAATTATAACAAGCTGCAGGAGTTCCCTGTGGCCATCCGGACCCTGGGCAGA
CTGCAGGAACTGGGGTTCCATAACAACAACATCAAGGCCATCCCAGAAAAGGCCTTCATGGGGAACCCTCTGCTACAGACGATACACTTT
TATGATAACCCAATCCAGTTTGTGGGAAGATCGGCATTCCAGTACCTGCCTAAACTCCACACACTATCTCTGAATGGTGCCATGGACATC
CAGGAGTTTCCAGATCTCAAAGGCACCACCAGCCTGGAGATCCTGACCCTGACCCGCGCAGGCATCCGGCTGCTCCCATCGGGGATGTGC
CAACAGCTGCCCAGGCTCCGAGTCCTGGAACTGTCTCACAATCAAATTGAGGAGCTGCCCAGCCTGCACAGGTGTCAGAAATTGGAGGAA
ATCGGCCTCCAACACAACCGCATCTGGGAAATTGGAGCTGACACCTTCAGCCAGCTGAGCTCCCTGCAAGCCCTGGATCTTAGCTGGAAC
GCCATCCGGTCCATCCACCCCGAGGCCTTCTCCACCCTGCACTCCCTGGTCAAGCTGGACCTGACAGACAACCAGCTGACCACACTGCCC
CTGGCTGGACTTGGGGGCTTGATGCATCTGAAGCTCAAAGGGAACCTTGCTCTCTCCCAGGCCTTCTCCAAGGACAGTTTCCCAAAACTG
AGGATCCTGGAGGTGCCTTATGCCTACCAGTGCTGTCCCTATGGGATGTGTGCCAGCTTCTTCAAGGCCTCTGGGCAGTGGGAGGCTGAA
GACCTTCACCTTGATGATGAGGAGTCTTCAAAAAGGCCCCTGGGCCTCCTTGCCAGACAAGCAGAGAACCACTATGACCAGGACCTGGAT
GAGCTCCAGCTGGAGATGGAGGACTCAAAGCCACACCCCAGTGTCCAGTGTAGCCCTACTCCAGGCCCCTTCAAGCCCTGTGAGTACCTC
TTTGAAAGCTGGGGCATCCGCCTGGCCGTGTGGGCCATCGTGTTGCTCTCCGTGCTCTGCAATGGACTGGTGCTGCTGACCGTGTTCGCT
GGCGGGCCTGTCCCCCTGCCCCCGGTCAAGTTTGTGGTAGGTGCGATTGCAGGCGCCAACACCTTGACTGGCATTTCCTGTGGCCTTCTA
GCCTCAGTCGATGCCCTGACCTTTGGTCAGTTCTCTGAGTACGGAGCCCGCTGGGAGACGGGGCTAGGCTGCCGGGCCACTGGCTTCCTG
GCAGTACTTGGGTCGGAGGCATCGGTGCTGCTGCTCACTCTGGCCGCAGTGCAGTGCAGCGTCTCCGTCTCCTGTGTCCGGGCCTATGGG
AAGTCCCCCTCCCTGGGCAGCGTTCGAGCAGGGGTCCTAGGCTGCCTGGCACTGGCAGGGCTGGCCGCCGCGCTGCCCCTGGCCTCAGTG
GGAGAATACGGGGCCTCCCCACTCTGCCTGCCCTACGCGCCACCTGAGGGTCAGCCAGCAGCCCTGGGCTTCACCGTGGCCCTGGTGATG
ATGAACTCCTTCTGTTTCCTGGTCGTGGCCGGTGCCTACATCAAACTGTACTGTGACCTGCCGCGGGGCGACTTTGAGGCCGTGTGGGAC
TGCGCCATGGTGAGGCACGTGGCCTGGCTCATCTTCGCAGACGGGCTCCTCTACTGTCCCGTGGCCTTCCTCAGCTTTGCCTCCATGCTG
GGCCTCTTCCCTGTCACGCCCGAGGCCGTCAAGTCTGTCCTGCTGGTGGTGCTGCCCCTGCCTGCCTGCCTCAACCCACTGCTGTACCTG
CTCTTCAACCCCCACTTCCGGGATGACCTTCGGCGGCTTCGGCCCCGCGCAGGGGACTCAGGGCCCCTAGCCTATGCTGCGGCCGGGGAG
CTGGAGAAGAGCTCCTGTGATTCTACCCAGGCCCTGGTAGCCTTCTCTGATGTGGATCTCATTCTGGAAGCTTCTGAAGCTGGGCGGCCC
CCTGGGCTGGAGACCTATGGCTTCCCCTCAGTGACCCTCATCTCCTGTCAGCAGCCAGGGGCCCCCAGGCTGGAGGGCAGCCATTGTGTA
GAGCCAGAGGGGAACCACTTTGGGAACCCCCAACCCTCCATGGATGGAGAACTGCTGCTGAGGGCAGAGGGATCTACGCCAGCAGGTGGA
GGCTTGTCAGGGGGTGGCGGCTTTCAGCCCTCTGGCTTGGCCTTTGCTTCACACGTGTAAATATCCCTCCCCATTCTTCTCTTCCCCTCT
CTTCCCTTTCCTCTCTCCCCCTCGGTGAATGATGGCTGCTTCTAAAACAAATACAACCAAAACTCAGCAGTGTGATCTATAGCAGGATGG
CCCAGTCCCTGGCTCCACTGATCACCTCTCTCCTGTGACCATCACCAACGGGTGCCTCTTGGCCTGGCTTTCCCTTGGCCTTCCTCAGCT
TCACCTTGATACTGGGCCTCTTCCTTGTCATGTCTGAAGCTGTGGACCAGAGACCTGGACTTTTGTCTGCTTAAGGGAAATGAGGGAAGT
AAAGACAGTGAAGGGGTGGAGGGTTGATCAGGGCACAGTGGACAGGGAGACCTCACAGAGAAAGGCCTGGAAGGTGATTTCCCGTGTGAC
TCATGGATAGGATACAAAATGTGTTCCATGTACCATTAATCTTGACATATGCCATGCATAAAGACTTCCTATTAAAATAAGCTTTGGAAG
AGATTACACATGATGTCTTTTTCTTAGAGATTCACAGTGCATGTTAGTGTAATAAAGAGATAAGTCCTACAGTAGTAAAATCTATTGAAC

>67767_67767_6_PPP1R12B-LGR6_PPP1R12B_chr1_202386045_ENST00000480184_LGR6_chr1_202245434_ENST00000367278_length(amino acids)=996AA_BP=172
MKRSERGGSGNSSPNSNLVLVVLAAAAEAGAMAELEHLGGKRAESARMRRAEQLRRWRGSLTEQEPAERRGAGRQPLTRRGSPRVRFEDG
AVFLAACSSGDTDEVRKLLARGADINTVNVDGLTALHQACIDENLDMVKFLVENRANVNQQDNEGWTPLHAAASCGYLNIAERLDANLIS
LVPERSFEGLSSLRHLWLDDNALTEIPVRALNNLPALQAMTLALNRISHIPDYAFQNLTSLVVLHLHNNRIQHLGTHSFEGLHNLETLDL
NYNKLQEFPVAIRTLGRLQELGFHNNNIKAIPEKAFMGNPLLQTIHFYDNPIQFVGRSAFQYLPKLHTLSLNGAMDIQEFPDLKGTTSLE
ILTLTRAGIRLLPSGMCQQLPRLRVLELSHNQIEELPSLHRCQKLEEIGLQHNRIWEIGADTFSQLSSLQALDLSWNAIRSIHPEAFSTL
HSLVKLDLTDNQLTTLPLAGLGGLMHLKLKGNLALSQAFSKDSFPKLRILEVPYAYQCCPYGMCASFFKASGQWEAEDLHLDDEESSKRP
LGLLARQAENHYDQDLDELQLEMEDSKPHPSVQCSPTPGPFKPCEYLFESWGIRLAVWAIVLLSVLCNGLVLLTVFAGGPVPLPPVKFVV
GAIAGANTLTGISCGLLASVDALTFGQFSEYGARWETGLGCRATGFLAVLGSEASVLLLTLAAVQCSVSVSCVRAYGKSPSLGSVRAGVL
GCLALAGLAAALPLASVGEYGASPLCLPYAPPEGQPAALGFTVALVMMNSFCFLVVAGAYIKLYCDLPRGDFEAVWDCAMVRHVAWLIFA
DGLLYCPVAFLSFASMLGLFPVTPEAVKSVLLVVLPLPACLNPLLYLLFNPHFRDDLRRLRPRAGDSGPLAYAAAGELEKSSCDSTQALV
AFSDVDLILEASEAGRPPGLETYGFPSVTLISCQQPGAPRLEGSHCVEPEGNHFGNPQPSMDGELLLRAEGSTPAGGGLSGGGGFQPSGL

--------------------------------------------------------------
>67767_67767_7_PPP1R12B-LGR6_PPP1R12B_chr1_202386045_ENST00000608999_LGR6_chr1_202245434_ENST00000255432_length(transcript)=3625nt_BP=575nt
GGTACTACTGGCGGGAGGAGTAAAGATGGCGGCGCGAGGGTCTCCGCCCTCTGCTCCGGGCTGAAGCGCTCTGAGAGAGGCGGCAGCGGC
AACTCGAGCCCCAACAGTAATTTAGTGTTGGTAGTTTTGGCAGCAGCTGCCGAGGCCGGAGCAATGGCGGAACTGGAGCACCTAGGAGGG
AAGCGGGCAGAGTCGGCGCGAATGCGGCGGGCAGAGCAGCTTCGGCGCTGGCGGGGCTCGCTGACAGAGCAGGAGCCTGCGGAGCGACGA
GGCGCGGGGCGGCAGCCGCTGACCAGGCGCGGGAGCCCCAGGGTCCGCTTCGAGGACGGTGCTGTCTTTCTGGCCGCCTGCTCTAGCGGG
GACACCGACGAGGTGAGAAAGCTTCTGGCAAGAGGTGCTGATATCAACACGGTCAACGTGGACGGCTTGACAGCCCTGCACCAGGCATGT
ATTGATGAAAATTTGGACATGGTGAAGTTTCTGGTGGAGAACAGAGCCAATGTAAACCAGCAAGACAACGAGGGCTGGACACCCCTTCAT
GCAGCAGCTTCCTGTGGCTATCTCAACATAGCAGAGCGCCTAGATGCCAACCTCATCTCCCTGGTCCCGGAGAGGAGCTTTGAGGGGCTG
TCCTCCCTCCGCCACCTCTGGCTGGACGACAATGCACTCACGGAGATCCCTGTCAGGGCCCTCAACAACCTCCCTGCCCTGCAGGCCATG
ACCCTGGCCCTCAACCGCATCAGCCACATCCCCGACTACGCGTTCCAGAATCTCACCAGCCTTGTGGTGCTGCATTTGCATAACAACCGC
ATCCAGCATCTGGGGACCCACAGCTTCGAGGGGCTGCACAATCTGGAGACACTAGACCTGAATTATAACAAGCTGCAGGAGTTCCCTGTG
GCCATCCGGACCCTGGGCAGACTGCAGGAACTGGGGTTCCATAACAACAACATCAAGGCCATCCCAGAAAAGGCCTTCATGGGGAACCCT
CTGCTACAGACGATACACTTTTATGATAACCCAATCCAGTTTGTGGGAAGATCGGCATTCCAGTACCTGCCTAAACTCCACACACTATCT
CTGAATGGTGCCATGGACATCCAGGAGTTTCCAGATCTCAAAGGCACCACCAGCCTGGAGATCCTGACCCTGACCCGCGCAGGCATCCGG
CTGCTCCCATCGGGGATGTGCCAACAGCTGCCCAGGCTCCGAGTCCTGGAACTGTCTCACAATCAAATTGAGGAGCTGCCCAGCCTGCAC
AGGTGTCAGAAATTGGAGGAAATCGGCCTCCAACACAACCGCATCTGGGAAATTGGAGCTGACACCTTCAGCCAGCTGAGCTCCCTGCAA
GCCCTGGATCTTAGCTGGAACGCCATCCGGTCCATCCACCCCGAGGCCTTCTCCACCCTGCACTCCCTGGTCAAGCTGGACCTGACAGAC
AACCAGCTGACCACACTGCCCCTGGCTGGACTTGGGGGCTTGATGCATCTGAAGCTCAAAGGGAACCTTGCTCTCTCCCAGGCCTTCTCC
AAGGACAGTTTCCCAAAACTGAGGATCCTGGAGGTGCCTTATGCCTACCAGTGCTGTCCCTATGGGATGTGTGCCAGCTTCTTCAAGGCC
TCTGGGCAGTGGGAGGCTGAAGACCTTCACCTTGATGATGAGGAGTCTTCAAAAAGGCCCCTGGGCCTCCTTGCCAGACAAGCAGAGAAC
CACTATGACCAGGACCTGGATGAGCTCCAGCTGGAGATGGAGGACTCAAAGCCACACCCCAGTGTCCAGTGTAGCCCTACTCCAGGCCCC
TTCAAGCCCTGTGAGTACCTCTTTGAAAGCTGGGGCATCCGCCTGGCCGTGTGGGCCATCGTGTTGCTCTCCGTGCTCTGCAATGGACTG
GTGCTGCTGACCGTGTTCGCTGGCGGGCCTGTCCCCCTGCCCCCGGTCAAGTTTGTGGTAGGTGCGATTGCAGGCGCCAACACCTTGACT
GGCATTTCCTGTGGCCTTCTAGCCTCAGTCGATGCCCTGACCTTTGGTCAGTTCTCTGAGTACGGAGCCCGCTGGGAGACGGGGCTAGGC
TGCCGGGCCACTGGCTTCCTGGCAGTACTTGGGTCGGAGGCATCGGTGCTGCTGCTCACTCTGGCCGCAGTGCAGTGCAGCGTCTCCGTC
TCCTGTGTCCGGGCCTATGGGAAGTCCCCCTCCCTGGGCAGCGTTCGAGCAGGGGTCCTAGGCTGCCTGGCACTGGCAGGGCTGGCCGCC
GCGCTGCCCCTGGCCTCAGTGGGAGAATACGGGGCCTCCCCACTCTGCCTGCCCTACGCGCCACCTGAGGGTCAGCCAGCAGCCCTGGGC
TTCACCGTGGCCCTGGTGATGATGAACTCCTTCTGTTTCCTGGTCGTGGCCGGTGCCTACATCAAACTGTACTGTGACCTGCCGCGGGGC
GACTTTGAGGCCGTGTGGGACTGCGCCATGGTGAGGCACGTGGCCTGGCTCATCTTCGCAGACGGGCTCCTCTACTGTCCCGTGGCCTTC
CTCAGCTTTGCCTCCATGCTGGGCCTCTTCCCTGTCACGCCCGAGGCCGTCAAGTCTGTCCTGCTGGTGGTGCTGCCCCTGCCTGCCTGC
CTCAACCCACTGCTGTACCTGCTCTTCAACCCCCACTTCCGGGATGACCTTCGGCGGCTTCGGCCCCGCGCAGGGGACTCAGGGCCCCTA
GCCTATGCTGCGGCCGGGGAGCTGGAGAAGAGCTCCTGTGATTCTACCCAGGCCCTGGTAGCCTTCTCTGATGTGGATCTCATTCTGGAA
GCTTCTGAAGCTGGGCGGCCCCCTGGGCTGGAGACCTATGGCTTCCCCTCAGTGACCCTCATCTCCTGTCAGCAGCCAGGGGCCCCCAGG
CTGGAGGGCAGCCATTGTGTAGAGCCAGAGGGGAACCACTTTGGGAACCCCCAACCCTCCATGGATGGAGAACTGCTGCTGAGGGCAGAG
GGATCTACGCCAGCAGGTGGAGGCTTGTCAGGGGGTGGCGGCTTTCAGCCCTCTGGCTTGGCCTTTGCTTCACACGTGTAAATATCCCTC
CCCATTCTTCTCTTCCCCTCTCTTCCCTTTCCTCTCTCCCCCTCGGTGAATGATGGCTGCTTCTAAAACAAATACAACCAAAACTCAGCA
GTGTGATCTATAGCAGGATGGCCCAGTCCCTGGCTCCACTGATCACCTCTCTCCTGTGACCATCACCAACGGGTGCCTCTTGGCCTGGCT
TTCCCTTGGCCTTCCTCAGCTTCACCTTGATACTGGGCCTCTTCCTTGTCATGTCTGAAGCTGTGGACCAGAGACCTGGACTTTTGTCTG
CTTAAGGGAAATGAGGGAAGTAAAGACAGTGAAGGGGTGGAGGGTTGATCAGGGCACAGTGGACAGGGAGACCTCACAGAGAAAGGCCTG
GAAGGTGATTTCCCGTGTGACTCATGGATAGGATACAAAATGTGTTCCATGTACCATTAATCTTGACATATGCCATGCATAAAGACTTCC
TATTAAAATAAGCTTTGGAAGAGATTACACATGATGTCTTTTTCTTAGAGATTCACAGTGCATGTTAGTGTAATAAAGAGATAAGTCCTA

>67767_67767_7_PPP1R12B-LGR6_PPP1R12B_chr1_202386045_ENST00000608999_LGR6_chr1_202245434_ENST00000255432_length(amino acids)=996AA_BP=172
MKRSERGGSGNSSPNSNLVLVVLAAAAEAGAMAELEHLGGKRAESARMRRAEQLRRWRGSLTEQEPAERRGAGRQPLTRRGSPRVRFEDG
AVFLAACSSGDTDEVRKLLARGADINTVNVDGLTALHQACIDENLDMVKFLVENRANVNQQDNEGWTPLHAAASCGYLNIAERLDANLIS
LVPERSFEGLSSLRHLWLDDNALTEIPVRALNNLPALQAMTLALNRISHIPDYAFQNLTSLVVLHLHNNRIQHLGTHSFEGLHNLETLDL
NYNKLQEFPVAIRTLGRLQELGFHNNNIKAIPEKAFMGNPLLQTIHFYDNPIQFVGRSAFQYLPKLHTLSLNGAMDIQEFPDLKGTTSLE
ILTLTRAGIRLLPSGMCQQLPRLRVLELSHNQIEELPSLHRCQKLEEIGLQHNRIWEIGADTFSQLSSLQALDLSWNAIRSIHPEAFSTL
HSLVKLDLTDNQLTTLPLAGLGGLMHLKLKGNLALSQAFSKDSFPKLRILEVPYAYQCCPYGMCASFFKASGQWEAEDLHLDDEESSKRP
LGLLARQAENHYDQDLDELQLEMEDSKPHPSVQCSPTPGPFKPCEYLFESWGIRLAVWAIVLLSVLCNGLVLLTVFAGGPVPLPPVKFVV
GAIAGANTLTGISCGLLASVDALTFGQFSEYGARWETGLGCRATGFLAVLGSEASVLLLTLAAVQCSVSVSCVRAYGKSPSLGSVRAGVL
GCLALAGLAAALPLASVGEYGASPLCLPYAPPEGQPAALGFTVALVMMNSFCFLVVAGAYIKLYCDLPRGDFEAVWDCAMVRHVAWLIFA
DGLLYCPVAFLSFASMLGLFPVTPEAVKSVLLVVLPLPACLNPLLYLLFNPHFRDDLRRLRPRAGDSGPLAYAAAGELEKSSCDSTQALV
AFSDVDLILEASEAGRPPGLETYGFPSVTLISCQQPGAPRLEGSHCVEPEGNHFGNPQPSMDGELLLRAEGSTPAGGGLSGGGGFQPSGL

--------------------------------------------------------------
>67767_67767_8_PPP1R12B-LGR6_PPP1R12B_chr1_202386045_ENST00000608999_LGR6_chr1_202245434_ENST00000367278_length(transcript)=3625nt_BP=575nt
GGTACTACTGGCGGGAGGAGTAAAGATGGCGGCGCGAGGGTCTCCGCCCTCTGCTCCGGGCTGAAGCGCTCTGAGAGAGGCGGCAGCGGC
AACTCGAGCCCCAACAGTAATTTAGTGTTGGTAGTTTTGGCAGCAGCTGCCGAGGCCGGAGCAATGGCGGAACTGGAGCACCTAGGAGGG
AAGCGGGCAGAGTCGGCGCGAATGCGGCGGGCAGAGCAGCTTCGGCGCTGGCGGGGCTCGCTGACAGAGCAGGAGCCTGCGGAGCGACGA
GGCGCGGGGCGGCAGCCGCTGACCAGGCGCGGGAGCCCCAGGGTCCGCTTCGAGGACGGTGCTGTCTTTCTGGCCGCCTGCTCTAGCGGG
GACACCGACGAGGTGAGAAAGCTTCTGGCAAGAGGTGCTGATATCAACACGGTCAACGTGGACGGCTTGACAGCCCTGCACCAGGCATGT
ATTGATGAAAATTTGGACATGGTGAAGTTTCTGGTGGAGAACAGAGCCAATGTAAACCAGCAAGACAACGAGGGCTGGACACCCCTTCAT
GCAGCAGCTTCCTGTGGCTATCTCAACATAGCAGAGCGCCTAGATGCCAACCTCATCTCCCTGGTCCCGGAGAGGAGCTTTGAGGGGCTG
TCCTCCCTCCGCCACCTCTGGCTGGACGACAATGCACTCACGGAGATCCCTGTCAGGGCCCTCAACAACCTCCCTGCCCTGCAGGCCATG
ACCCTGGCCCTCAACCGCATCAGCCACATCCCCGACTACGCGTTCCAGAATCTCACCAGCCTTGTGGTGCTGCATTTGCATAACAACCGC
ATCCAGCATCTGGGGACCCACAGCTTCGAGGGGCTGCACAATCTGGAGACACTAGACCTGAATTATAACAAGCTGCAGGAGTTCCCTGTG
GCCATCCGGACCCTGGGCAGACTGCAGGAACTGGGGTTCCATAACAACAACATCAAGGCCATCCCAGAAAAGGCCTTCATGGGGAACCCT
CTGCTACAGACGATACACTTTTATGATAACCCAATCCAGTTTGTGGGAAGATCGGCATTCCAGTACCTGCCTAAACTCCACACACTATCT
CTGAATGGTGCCATGGACATCCAGGAGTTTCCAGATCTCAAAGGCACCACCAGCCTGGAGATCCTGACCCTGACCCGCGCAGGCATCCGG
CTGCTCCCATCGGGGATGTGCCAACAGCTGCCCAGGCTCCGAGTCCTGGAACTGTCTCACAATCAAATTGAGGAGCTGCCCAGCCTGCAC
AGGTGTCAGAAATTGGAGGAAATCGGCCTCCAACACAACCGCATCTGGGAAATTGGAGCTGACACCTTCAGCCAGCTGAGCTCCCTGCAA
GCCCTGGATCTTAGCTGGAACGCCATCCGGTCCATCCACCCCGAGGCCTTCTCCACCCTGCACTCCCTGGTCAAGCTGGACCTGACAGAC
AACCAGCTGACCACACTGCCCCTGGCTGGACTTGGGGGCTTGATGCATCTGAAGCTCAAAGGGAACCTTGCTCTCTCCCAGGCCTTCTCC
AAGGACAGTTTCCCAAAACTGAGGATCCTGGAGGTGCCTTATGCCTACCAGTGCTGTCCCTATGGGATGTGTGCCAGCTTCTTCAAGGCC
TCTGGGCAGTGGGAGGCTGAAGACCTTCACCTTGATGATGAGGAGTCTTCAAAAAGGCCCCTGGGCCTCCTTGCCAGACAAGCAGAGAAC
CACTATGACCAGGACCTGGATGAGCTCCAGCTGGAGATGGAGGACTCAAAGCCACACCCCAGTGTCCAGTGTAGCCCTACTCCAGGCCCC
TTCAAGCCCTGTGAGTACCTCTTTGAAAGCTGGGGCATCCGCCTGGCCGTGTGGGCCATCGTGTTGCTCTCCGTGCTCTGCAATGGACTG
GTGCTGCTGACCGTGTTCGCTGGCGGGCCTGTCCCCCTGCCCCCGGTCAAGTTTGTGGTAGGTGCGATTGCAGGCGCCAACACCTTGACT
GGCATTTCCTGTGGCCTTCTAGCCTCAGTCGATGCCCTGACCTTTGGTCAGTTCTCTGAGTACGGAGCCCGCTGGGAGACGGGGCTAGGC
TGCCGGGCCACTGGCTTCCTGGCAGTACTTGGGTCGGAGGCATCGGTGCTGCTGCTCACTCTGGCCGCAGTGCAGTGCAGCGTCTCCGTC
TCCTGTGTCCGGGCCTATGGGAAGTCCCCCTCCCTGGGCAGCGTTCGAGCAGGGGTCCTAGGCTGCCTGGCACTGGCAGGGCTGGCCGCC
GCGCTGCCCCTGGCCTCAGTGGGAGAATACGGGGCCTCCCCACTCTGCCTGCCCTACGCGCCACCTGAGGGTCAGCCAGCAGCCCTGGGC
TTCACCGTGGCCCTGGTGATGATGAACTCCTTCTGTTTCCTGGTCGTGGCCGGTGCCTACATCAAACTGTACTGTGACCTGCCGCGGGGC
GACTTTGAGGCCGTGTGGGACTGCGCCATGGTGAGGCACGTGGCCTGGCTCATCTTCGCAGACGGGCTCCTCTACTGTCCCGTGGCCTTC
CTCAGCTTTGCCTCCATGCTGGGCCTCTTCCCTGTCACGCCCGAGGCCGTCAAGTCTGTCCTGCTGGTGGTGCTGCCCCTGCCTGCCTGC
CTCAACCCACTGCTGTACCTGCTCTTCAACCCCCACTTCCGGGATGACCTTCGGCGGCTTCGGCCCCGCGCAGGGGACTCAGGGCCCCTA
GCCTATGCTGCGGCCGGGGAGCTGGAGAAGAGCTCCTGTGATTCTACCCAGGCCCTGGTAGCCTTCTCTGATGTGGATCTCATTCTGGAA
GCTTCTGAAGCTGGGCGGCCCCCTGGGCTGGAGACCTATGGCTTCCCCTCAGTGACCCTCATCTCCTGTCAGCAGCCAGGGGCCCCCAGG
CTGGAGGGCAGCCATTGTGTAGAGCCAGAGGGGAACCACTTTGGGAACCCCCAACCCTCCATGGATGGAGAACTGCTGCTGAGGGCAGAG
GGATCTACGCCAGCAGGTGGAGGCTTGTCAGGGGGTGGCGGCTTTCAGCCCTCTGGCTTGGCCTTTGCTTCACACGTGTAAATATCCCTC
CCCATTCTTCTCTTCCCCTCTCTTCCCTTTCCTCTCTCCCCCTCGGTGAATGATGGCTGCTTCTAAAACAAATACAACCAAAACTCAGCA
GTGTGATCTATAGCAGGATGGCCCAGTCCCTGGCTCCACTGATCACCTCTCTCCTGTGACCATCACCAACGGGTGCCTCTTGGCCTGGCT
TTCCCTTGGCCTTCCTCAGCTTCACCTTGATACTGGGCCTCTTCCTTGTCATGTCTGAAGCTGTGGACCAGAGACCTGGACTTTTGTCTG
CTTAAGGGAAATGAGGGAAGTAAAGACAGTGAAGGGGTGGAGGGTTGATCAGGGCACAGTGGACAGGGAGACCTCACAGAGAAAGGCCTG
GAAGGTGATTTCCCGTGTGACTCATGGATAGGATACAAAATGTGTTCCATGTACCATTAATCTTGACATATGCCATGCATAAAGACTTCC
TATTAAAATAAGCTTTGGAAGAGATTACACATGATGTCTTTTTCTTAGAGATTCACAGTGCATGTTAGTGTAATAAAGAGATAAGTCCTA

>67767_67767_8_PPP1R12B-LGR6_PPP1R12B_chr1_202386045_ENST00000608999_LGR6_chr1_202245434_ENST00000367278_length(amino acids)=996AA_BP=172
MKRSERGGSGNSSPNSNLVLVVLAAAAEAGAMAELEHLGGKRAESARMRRAEQLRRWRGSLTEQEPAERRGAGRQPLTRRGSPRVRFEDG
AVFLAACSSGDTDEVRKLLARGADINTVNVDGLTALHQACIDENLDMVKFLVENRANVNQQDNEGWTPLHAAASCGYLNIAERLDANLIS
LVPERSFEGLSSLRHLWLDDNALTEIPVRALNNLPALQAMTLALNRISHIPDYAFQNLTSLVVLHLHNNRIQHLGTHSFEGLHNLETLDL
NYNKLQEFPVAIRTLGRLQELGFHNNNIKAIPEKAFMGNPLLQTIHFYDNPIQFVGRSAFQYLPKLHTLSLNGAMDIQEFPDLKGTTSLE
ILTLTRAGIRLLPSGMCQQLPRLRVLELSHNQIEELPSLHRCQKLEEIGLQHNRIWEIGADTFSQLSSLQALDLSWNAIRSIHPEAFSTL
HSLVKLDLTDNQLTTLPLAGLGGLMHLKLKGNLALSQAFSKDSFPKLRILEVPYAYQCCPYGMCASFFKASGQWEAEDLHLDDEESSKRP
LGLLARQAENHYDQDLDELQLEMEDSKPHPSVQCSPTPGPFKPCEYLFESWGIRLAVWAIVLLSVLCNGLVLLTVFAGGPVPLPPVKFVV
GAIAGANTLTGISCGLLASVDALTFGQFSEYGARWETGLGCRATGFLAVLGSEASVLLLTLAAVQCSVSVSCVRAYGKSPSLGSVRAGVL
GCLALAGLAAALPLASVGEYGASPLCLPYAPPEGQPAALGFTVALVMMNSFCFLVVAGAYIKLYCDLPRGDFEAVWDCAMVRHVAWLIFA
DGLLYCPVAFLSFASMLGLFPVTPEAVKSVLLVVLPLPACLNPLLYLLFNPHFRDDLRRLRPRAGDSGPLAYAAAGELEKSSCDSTQALV
AFSDVDLILEASEAGRPPGLETYGFPSVTLISCQQPGAPRLEGSHCVEPEGNHFGNPQPSMDGELLLRAEGSTPAGGGLSGGGGFQPSGL

--------------------------------------------------------------

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Fusion Gene PPI Analysis for PPP1R12B-LGR6


check button Go to ChiPPI (Chimeric Protein-Protein interactions) to see the chimeric PPI interaction in

ChiPPI page.


check button Protein-protein interactors with each fusion partner protein in wild-type (BIOGRID-3.4.160)
HgeneHgene's interactorsTgeneTgene's interactors


check button - Retained PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenStill interaction with


check button - Lost PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


check button - Retained PPIs, but lost function due to frame-shift fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


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Related Drugs for PPP1R12B-LGR6


check button Drugs targeting genes involved in this fusion gene.
(DrugBank Version 5.1.8 2021-05-08)
PartnerGeneUniProtAccDrugBank IDDrug nameDrug activityDrug typeDrug status

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Related Diseases for PPP1R12B-LGR6


check button Diseases associated with fusion partners.
(DisGeNet 4.0)
PartnerGeneDisease IDDisease name# pubmedsSource