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Center for Computational Systems Medicine
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Fusion Gene Summary

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Fusion Gene ORF analysis

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Fusion Genomic Features

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Fusion Protein Features

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Fusion Gene Sequence

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Fusion Gene PPI analysis

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Related Drugs

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Related Diseases

Fusion gene:PPP1R13B-PTPRA (FusionGDB2 ID:67814)

Fusion Gene Summary for PPP1R13B-PTPRA

check button Fusion gene summary
Fusion gene informationFusion gene name: PPP1R13B-PTPRA
Fusion gene ID: 67814
HgeneTgene
Gene symbol

PPP1R13B

PTPRA

Gene ID

23368

5786

Gene nameprotein phosphatase 1 regulatory subunit 13Bprotein tyrosine phosphatase receptor type A
SynonymsASPP1|p53BP2-like|p85HEPTP|HLPR|HPTPA|HPTPalpha|LRP|PTPA|PTPRL2|R-PTP-alpha|RPTPA
Cytomap

14q32.33

20p13

Type of geneprotein-codingprotein-coding
Descriptionapoptosis-stimulating of p53 protein 1apoptosis-stimulating protein of p53, 1protein phosphatase 1, regulatory (inhibitor) subunit 13Breceptor-type tyrosine-protein phosphatase alphaLeukocyte common antigen-related peptide (protein tyrosine phosphate)PTPLCA-related phosphatasePTPase-alphaprotein tyrosine phosphatase, receptor type, alpha polypeptideprotein-tyrosine phosphatase alph
Modification date2020031320200327
UniProtAcc..
Ensembl transtripts involved in fusion geneENST00000202556, ENST00000423488, 
ENST00000555391, 		ENST00000216877, 
ENST00000318266, ENST00000356147, 
ENST00000358719, ENST00000380393, 
ENST00000399903, ENST00000425918, 
Fusion gene scores* DoF score16 X 10 X 10=16009 X 9 X 2=162
# samples 229
** MAII scorelog2(22/1600*10)=-2.86249647625006
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0		log2(9/162*10)=-0.84799690655495
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0
Context

PubMed: PPP1R13B [Title/Abstract] AND PTPRA [Title/Abstract] AND fusion [Title/Abstract]

Most frequent breakpointPPP1R13B(104313636)-PTPRA(2985702), # samples:1
Anticipated loss of major functional domain due to fusion event.
* DoF score (Degree of Frequency) = # partners X # break points X # cancer types
** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10)

check button Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez
PartnerGeneGO IDGO termPubMed ID
HgenePPP1R13B

GO:0072332

intrinsic apoptotic signaling pathway by p53 class mediator

11684014


check buttonFusion gene breakpoints across PPP1R13B (5'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.
all structure

check buttonFusion gene breakpoints across PTPRA (3'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.
all structure

check button Fusion gene information from two resources (ChiTars 5.0 and ChimerDB 4.0)
* All genome coordinats were lifted-over on hg19.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
SourceDiseaseSampleHgeneHchrHbpHstrandTgeneTchrTbpTstrand
ChimerDB4STADTCGA-IN-7808-01APPP1R13Bchr14

104313636

-PTPRAchr20

2985702

+


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Fusion Gene ORF analysis for PPP1R13B-PTPRA

check button Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
ORFHenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrand
In-frameENST00000202556ENST00000216877PPP1R13Bchr14

104313636

-PTPRAchr20

2985702

+
In-frameENST00000202556ENST00000318266PPP1R13Bchr14

104313636

-PTPRAchr20

2985702

+
In-frameENST00000202556ENST00000356147PPP1R13Bchr14

104313636

-PTPRAchr20

2985702

+
In-frameENST00000202556ENST00000358719PPP1R13Bchr14

104313636

-PTPRAchr20

2985702

+
In-frameENST00000202556ENST00000380393PPP1R13Bchr14

104313636

-PTPRAchr20

2985702

+
In-frameENST00000202556ENST00000399903PPP1R13Bchr14

104313636

-PTPRAchr20

2985702

+
In-frameENST00000202556ENST00000425918PPP1R13Bchr14

104313636

-PTPRAchr20

2985702

+
intron-3CDSENST00000423488ENST00000216877PPP1R13Bchr14

104313636

-PTPRAchr20

2985702

+
intron-3CDSENST00000423488ENST00000318266PPP1R13Bchr14

104313636

-PTPRAchr20

2985702

+
intron-3CDSENST00000423488ENST00000356147PPP1R13Bchr14

104313636

-PTPRAchr20

2985702

+
intron-3CDSENST00000423488ENST00000358719PPP1R13Bchr14

104313636

-PTPRAchr20

2985702

+
intron-3CDSENST00000423488ENST00000380393PPP1R13Bchr14

104313636

-PTPRAchr20

2985702

+
intron-3CDSENST00000423488ENST00000399903PPP1R13Bchr14

104313636

-PTPRAchr20

2985702

+
intron-3CDSENST00000423488ENST00000425918PPP1R13Bchr14

104313636

-PTPRAchr20

2985702

+
intron-3CDSENST00000555391ENST00000216877PPP1R13Bchr14

104313636

-PTPRAchr20

2985702

+
intron-3CDSENST00000555391ENST00000318266PPP1R13Bchr14

104313636

-PTPRAchr20

2985702

+
intron-3CDSENST00000555391ENST00000356147PPP1R13Bchr14

104313636

-PTPRAchr20

2985702

+
intron-3CDSENST00000555391ENST00000358719PPP1R13Bchr14

104313636

-PTPRAchr20

2985702

+
intron-3CDSENST00000555391ENST00000380393PPP1R13Bchr14

104313636

-PTPRAchr20

2985702

+
intron-3CDSENST00000555391ENST00000399903PPP1R13Bchr14

104313636

-PTPRAchr20

2985702

+
intron-3CDSENST00000555391ENST00000425918PPP1R13Bchr14

104313636

-PTPRAchr20

2985702

+

check buttonORFfinder result based on the fusion transcript sequence of in-frame fusion genes.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandSeq length
(transcript)		BP loci
(transcript)		Predicted start
(transcript)		Predicted stop
(transcript)		Seq length
(amino acids)
ENST00000202556PPP1R13Bchr14104313636-ENST00000380393PTPRAchr202985702+25042922831962559
ENST00000202556PPP1R13Bchr14104313636-ENST00000216877PTPRAchr202985702+29062922831962559
ENST00000202556PPP1R13Bchr14104313636-ENST00000358719PTPRAchr202985702+24982922831962559
ENST00000202556PPP1R13Bchr14104313636-ENST00000399903PTPRAchr202985702+24982922831962559
ENST00000202556PPP1R13Bchr14104313636-ENST00000425918PTPRAchr202985702+22092922831962559
ENST00000202556PPP1R13Bchr14104313636-ENST00000318266PTPRAchr202985702+25042922831962559
ENST00000202556PPP1R13Bchr14104313636-ENST00000356147PTPRAchr202985702+24982922831962559

check buttonDeepORF prediction of the coding potential based on the fusion transcript sequence of in-frame fusion genes. DeepORF is a coding potential classifier based on convolutional neural network by comparing the real Ribo-seq data. If the no-coding score < 0.5 and coding score > 0.5, then the in-frame fusion transcript is predicted as being likely translated.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandNo-coding scoreCoding score
ENST00000202556ENST00000380393PPP1R13Bchr14104313636-PTPRAchr202985702+0.0019237830.9980762
ENST00000202556ENST00000216877PPP1R13Bchr14104313636-PTPRAchr202985702+0.0013469950.99865294
ENST00000202556ENST00000358719PPP1R13Bchr14104313636-PTPRAchr202985702+0.001914360.9980856
ENST00000202556ENST00000399903PPP1R13Bchr14104313636-PTPRAchr202985702+0.001914360.9980856
ENST00000202556ENST00000425918PPP1R13Bchr14104313636-PTPRAchr202985702+0.0025197490.9974802
ENST00000202556ENST00000318266PPP1R13Bchr14104313636-PTPRAchr202985702+0.0019237830.9980762
ENST00000202556ENST00000356147PPP1R13Bchr14104313636-PTPRAchr202985702+0.001914360.9980856

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Fusion Genomic Features for PPP1R13B-PTPRA


check buttonFusionAI prediction of the potential fusion gene breakpoint based on the pre-mature RNA sequence context (+/- 5kb of individual partner genes, total 20kb length sequence). FusionAI is a fusion gene breakpoint classifier based on convolutional neural network by comparing the fusion positive and negative sequence context of ~ 20K fusion gene data. From here, we can have the relative potentency of the 20K genomic sequence how individual sequnce will be likely used as the gene fusion breakpoints.
HgeneHchrHbpHstrandTgeneTchrTbpTstrand1-pp (fusion gene breakpoint)
PPP1R13Bchr14104313635-PTPRAchr202985701+1.92E-131
PPP1R13Bchr14104313635-PTPRAchr202985701+1.92E-131

check buttonDistribution of 44 human genomic features loci across 20kb length fusion breakpoint regions. We integrated a total of 44 different types of human genomic feature loci information across five big categories including virus integration sites, repeats, structural variants, chromatin states, and gene expression regulation. More details are in help page.
genomic feature

check buttonDistribution of 44 human genomic features loci across 20kb length fusion breakpoint regions that are ovelapped with the top 1% feature importance score regions. More details are in help page.
genomic feature of top 1%

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Fusion Protein Features for PPP1R13B-PTPRA


check button Four levels of functional features of fusion genes
Go to FGviewer search page for the most frequent breakpoint (https://ccsmweb.uth.edu/FGviewer/chr14:104313636/chr20:2985702)
- FGviewer provides the online visualization of the retention search of the protein functional features across DNA, RNA, protein, and pathological levels.
- How to search
1. Put your fusion gene symbol.
2. Press the tab key until there will be shown the breakpoint information filled.
4. Go down and press 'Search' tab twice.
4. Go down to have the hyperlink of the search result.
5. Click the hyperlink.
6. See the FGviewer result for your fusion gene.
FGviewer

check buttonMain function of each fusion partner protein. (from UniProt)
HgeneTgene
..
FUNCTION: Transcriptional activator which is required for calcium-dependent dendritic growth and branching in cortical neurons. Recruits CREB-binding protein (CREBBP) to nuclear bodies. Component of the CREST-BRG1 complex, a multiprotein complex that regulates promoter activation by orchestrating a calcium-dependent release of a repressor complex and a recruitment of an activator complex. In resting neurons, transcription of the c-FOS promoter is inhibited by BRG1-dependent recruitment of a phospho-RB1-HDAC1 repressor complex. Upon calcium influx, RB1 is dephosphorylated by calcineurin, which leads to release of the repressor complex. At the same time, there is increased recruitment of CREBBP to the promoter by a CREST-dependent mechanism, which leads to transcriptional activation. The CREST-BRG1 complex also binds to the NR2B promoter, and activity-dependent induction of NR2B expression involves a release of HDAC1 and recruitment of CREBBP (By similarity). {ECO:0000250}.FUNCTION: Transcriptional activator which is required for calcium-dependent dendritic growth and branching in cortical neurons. Recruits CREB-binding protein (CREBBP) to nuclear bodies. Component of the CREST-BRG1 complex, a multiprotein complex that regulates promoter activation by orchestrating a calcium-dependent release of a repressor complex and a recruitment of an activator complex. In resting neurons, transcription of the c-FOS promoter is inhibited by BRG1-dependent recruitment of a phospho-RB1-HDAC1 repressor complex. Upon calcium influx, RB1 is dephosphorylated by calcineurin, which leads to release of the repressor complex. At the same time, there is increased recruitment of CREBBP to the promoter by a CREST-dependent mechanism, which leads to transcriptional activation. The CREST-BRG1 complex also binds to the NR2B promoter, and activity-dependent induction of NR2B expression involves a release of HDAC1 and recruitment of CREBBP (By similarity). {ECO:0000250}.

check buttonRetention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at

download page


* Minus value of BPloci means that the break pointn is located before the CDS.
- In-frame and retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
TgenePTPRAchr14:104313636chr20:2985702ENST00000216877723241_501237794.0DomainTyrosine-protein phosphatase 1
TgenePTPRAchr14:104313636chr20:2985702ENST00000216877723533_791237794.0DomainTyrosine-protein phosphatase 2
TgenePTPRAchr14:104313636chr20:2985702ENST00000318266824241_501237794.0DomainTyrosine-protein phosphatase 1
TgenePTPRAchr14:104313636chr20:2985702ENST00000318266824533_791237794.0DomainTyrosine-protein phosphatase 2
TgenePTPRAchr14:104313636chr20:2985702ENST00000356147723241_501237794.0DomainTyrosine-protein phosphatase 1
TgenePTPRAchr14:104313636chr20:2985702ENST00000356147723533_791237794.0DomainTyrosine-protein phosphatase 2
TgenePTPRAchr14:104313636chr20:2985702ENST000003803931228533_791246803.0DomainTyrosine-protein phosphatase 2
TgenePTPRAchr14:104313636chr20:2985702ENST00000399903824533_791246803.0DomainTyrosine-protein phosphatase 2
TgenePTPRAchr14:104313636chr20:2985702ENST00000216877723442_448237794.0RegionSubstrate binding
TgenePTPRAchr14:104313636chr20:2985702ENST00000318266824442_448237794.0RegionSubstrate binding
TgenePTPRAchr14:104313636chr20:2985702ENST00000356147723442_448237794.0RegionSubstrate binding
TgenePTPRAchr14:104313636chr20:2985702ENST000003803931228442_448246803.0RegionSubstrate binding
TgenePTPRAchr14:104313636chr20:2985702ENST00000399903824442_448246803.0RegionSubstrate binding

- In-frame and not-retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
HgenePPP1R13Bchr14:104313636chr20:2985702ENST00000202556-117132_29231091.0Compositional biasNote=Gln-rich
HgenePPP1R13Bchr14:104313636chr20:2985702ENST00000202556-117428_86031091.0Compositional biasNote=Pro-rich
HgenePPP1R13Bchr14:104313636chr20:2985702ENST00000202556-1171019_108131091.0DomainSH3
HgenePPP1R13Bchr14:104313636chr20:2985702ENST00000202556-117920_95231091.0RepeatNote=ANK 1
HgenePPP1R13Bchr14:104313636chr20:2985702ENST00000202556-117953_98531091.0RepeatNote=ANK 2
TgenePTPRAchr14:104313636chr20:2985702ENST000003803931228241_501246803.0DomainTyrosine-protein phosphatase 1
TgenePTPRAchr14:104313636chr20:2985702ENST00000399903824241_501246803.0DomainTyrosine-protein phosphatase 1
TgenePTPRAchr14:104313636chr20:2985702ENST00000216877723175_802237794.0Topological domainCytoplasmic
TgenePTPRAchr14:104313636chr20:2985702ENST0000021687772320_151237794.0Topological domainExtracellular
TgenePTPRAchr14:104313636chr20:2985702ENST00000318266824175_802237794.0Topological domainCytoplasmic
TgenePTPRAchr14:104313636chr20:2985702ENST0000031826682420_151237794.0Topological domainExtracellular
TgenePTPRAchr14:104313636chr20:2985702ENST00000356147723175_802237794.0Topological domainCytoplasmic
TgenePTPRAchr14:104313636chr20:2985702ENST0000035614772320_151237794.0Topological domainExtracellular
TgenePTPRAchr14:104313636chr20:2985702ENST000003803931228175_802246803.0Topological domainCytoplasmic
TgenePTPRAchr14:104313636chr20:2985702ENST00000380393122820_151246803.0Topological domainExtracellular
TgenePTPRAchr14:104313636chr20:2985702ENST00000399903824175_802246803.0Topological domainCytoplasmic
TgenePTPRAchr14:104313636chr20:2985702ENST0000039990382420_151246803.0Topological domainExtracellular
TgenePTPRAchr14:104313636chr20:2985702ENST00000216877723152_174237794.0TransmembraneHelical
TgenePTPRAchr14:104313636chr20:2985702ENST00000318266824152_174237794.0TransmembraneHelical
TgenePTPRAchr14:104313636chr20:2985702ENST00000356147723152_174237794.0TransmembraneHelical
TgenePTPRAchr14:104313636chr20:2985702ENST000003803931228152_174246803.0TransmembraneHelical
TgenePTPRAchr14:104313636chr20:2985702ENST00000399903824152_174246803.0TransmembraneHelical


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Fusion Gene Sequence for PPP1R13B-PTPRA


check button For in-frame fusion transcripts, we provide the fusion transcript sequences and fusion amino acid sequences. To have fusion amino acid sequence, we ran ORFfinder and chose the longest ORF among the all predicted ones.
>67814_67814_1_PPP1R13B-PTPRA_PPP1R13B_chr14_104313636_ENST00000202556_PTPRA_chr20_2985702_ENST00000216877_length(transcript)=2906nt_BP=292nt
GGGCGGGCGGGCCGCAGGCTGTCGGGCTGGGGCTGAGGCTGAGGCTGAGGTTGAGGCGGCGGCGGCGGCGGCCGGGTGCCCGGGACAGCG
ACGCAGCGCGCCGGCGGCCGCGACAGGGCCAGCGAGAGCCCCGCAGCCCGCCGCAGCTGCCGCCTCGCCGCGGCCGGGCCGGAGAGCACG
GCGGCGGGAGCGCGGCCTTAGGAGGCGGCCGGAGCGGTGGGCACAGCTCGGCGCGGAGCGTCCTGTCAGGCGGCGGCCGAGGGCGTCGCG
GACTCTCCCCGCGATGATGCCGGCTCTCCCTGCATGTCCTATCCAGGCCACCTGTGAGGCTGCTTCCAAGGAGGAAAACAAGGAAAAAAA
TCGATATGTAAACATCTTGCCTTATGACCACTCTAGAGTCCACCTGACACCGGTTGAAGGGGTTCCAGATTCTGATTACATCAATGCTTC
ATTCATCAACGGCTACCAAGAAAAGAACAAATTCATTGCTGCACAAGGACCAAAAGAAGAAACGGTGAATGATTTCTGGCGGATGATCTG
GGAACAAAACACAGCCACCATCGTCATGGTTACCAACCTGAAGGAGAGAAAGGAGTGCAAGTGCGCCCAGTACTGGCCAGACCAAGGCTG
CTGGACCTATGGGAATATTCGGGTGTCTGTAGAGGATGTGACTGTCCTGGTGGACTACACAGTACGGAAGTTCTGCATCCAGCAGGTGGG
CGACATGACCAACAGAAAGCCACAGCGCCTCATCACTCAGTTCCACTTTACCAGCTGGCCAGACTTTGGGGTGCCTTTTACCCCGATCGG
CATGCTCAAGTTCCTCAAGAAGGTGAAGGCCTGTAACCCTCAGTATGCAGGGGCCATCGTGGTCCACTGCAGTGCAGGTGTAGGGCGTAC
AGGTACCTTTGTCGTCATTGATGCCATGCTGGACATGATGCATACAGAACGGAAGGTGGACGTGTATGGCTTTGTGAGCCGGATCCGGGC
ACAGCGCTGCCAGATGGTGCAAACCGATATGCAGTATGTCTTCATATACCAAGCCCTTCTGGAGCATTATCTCTATGGAGATACAGAACT
GGAAGTGACCTCTCTAGAAACCCACCTGCAGAAAATTTACAACAAAATCCCAGGGACCAGCAACAATGGATTAGAGGAGGAGTTTAAGAA
GTTAACATCAATCAAAATCCAGAATGACAAGATGCGGACTGGAAACCTTCCAGCCAACATGAAGAAGAACCGTGTTTTACAGATCATTCC
ATATGAATTCAACAGAGTGATCATTCCAGTTAAGCGGGGCGAAGAGAATACAGACTATGTGAACGCATCCTTTATTGATGGCTACCGGCA
GAAGGACTCCTATATCGCCAGCCAGGGCCCTCTTCTCCACACAATTGAGGACTTCTGGCGAATGATCTGGGAGTGGAAATCCTGCTCTAT
CGTGATGCTAACAGAACTGGAGGAGAGAGGCCAGGAGAAGTGTGCCCAGTACTGGCCATCTGATGGACTGGTGTCCTATGGAGATATTAC
AGTGGAACTGAAGAAGGAGGAGGAATGTGAGAGCTACACCGTCCGAGACCTCCTGGTCACCAACACCAGGGAGAATAAGAGCCGGCAGAT
CCGGCAGTTCCACTTCCATGGCTGGCCTGAAGTGGGCATCCCCAGTGACGGAAAGGGCATGATCAGCATCATCGCCGCCGTGCAGAAGCA
GCAGCAGCAGTCAGGGAACCACCCCATCACCGTGCACTGCAGCGCCGGGGCAGGAAGGACGGGGACCTTCTGTGCCCTGAGCACCGTCCT
GGAGCGTGTGAAAGCAGAGGGGATTTTGGATGTCTTCCAGACTGTCAAGAGCCTGCGGCTACAGAGGCCACACATGGTCCAGACACTGGA
ACAGTATGAGTTCTGCTACAAGGTGGTGCAGGAGTATATTGATGCATTCTCAGATTATGCCAACTTCAAGTAAGCGGCAACAAGGGTCCG
TGGACCAGGAGGATTGCCTTTAATATTTTGTAATATTCTGTTTTGTTAATATACCCCAAATTGTGTATATATCTTATAACTGTTTTAGAA
ATTGGTACATAGGCTTCTATTACCTATTAGGTGGAAATTTTATATGTAAATGTGTTAGCACTGATAGTCCTTTTTCCAATGTTTTATTGG
GGAATTAAATAGTGTGATGTTTGGATTGATATCGTGAAATCCTCAGCCGAGAAATTGGGCTGGATTGTGCTTTGGTTAATACATCTTTCC
CTAAAGAAGATAAACACAAAATCCATTCCAGGTAGCTCGGCACCAACTAAGAAAAAAAGCACAAAGTTCTCAGAGCTCTCGAGGAAAGTG
GTTGTCCCCGTACCACCATGCACTGTAAATATCCCTCCCCTCTCTCCCTGGTCCCCTCCCCCATCCCCACCACTGATATCATGGGGAGTA
ATAGGACCAGAGCGGTATCTCTGGCACCACACTAGGGACTATCAGGTAATAAAAGCTTTGACTCCCTGAGGAAATGTCTCTCCCTTTGTC
TGGGGGTGGGGCAGCCATACAGGCTGGGGCTCTCCTCGGCTGTTCATGGCCCTCCTGTTGCTGTTCTCTCTGAGTTATCTGAGAGAGGCC
ACAGTCCCCCAGCTCCTCCTGTCCACCAAACACAGCCCTTCCAGTTCTTAGGTGATCTCCAGGACCCTCCTTTCATTCCCAGCACATCTT
TGGTTTAGTGGTCCTGGCCAGCCTCCCTCCCTAGGAAGGTGGCCAGGTCCTCACTGAGTCTCCTTAAGGACAGGGGCACAGGGGAGACTA
GAGCTGGCTCAGCTTTGGGCTGAGGCCAGTCTGACCTCTCCAGTCTGTGGTGCTTTGCTACAAAACTGTCTGGATTGTGTCACCCTATCT

>67814_67814_1_PPP1R13B-PTPRA_PPP1R13B_chr14_104313636_ENST00000202556_PTPRA_chr20_2985702_ENST00000216877_length(amino acids)=559AA_BP=3
MMPALPACPIQATCEAASKEENKEKNRYVNILPYDHSRVHLTPVEGVPDSDYINASFINGYQEKNKFIAAQGPKEETVNDFWRMIWEQNT
ATIVMVTNLKERKECKCAQYWPDQGCWTYGNIRVSVEDVTVLVDYTVRKFCIQQVGDMTNRKPQRLITQFHFTSWPDFGVPFTPIGMLKF
LKKVKACNPQYAGAIVVHCSAGVGRTGTFVVIDAMLDMMHTERKVDVYGFVSRIRAQRCQMVQTDMQYVFIYQALLEHYLYGDTELEVTS
LETHLQKIYNKIPGTSNNGLEEEFKKLTSIKIQNDKMRTGNLPANMKKNRVLQIIPYEFNRVIIPVKRGEENTDYVNASFIDGYRQKDSY
IASQGPLLHTIEDFWRMIWEWKSCSIVMLTELEERGQEKCAQYWPSDGLVSYGDITVELKKEEECESYTVRDLLVTNTRENKSRQIRQFH
FHGWPEVGIPSDGKGMISIIAAVQKQQQQSGNHPITVHCSAGAGRTGTFCALSTVLERVKAEGILDVFQTVKSLRLQRPHMVQTLEQYEF

--------------------------------------------------------------
>67814_67814_2_PPP1R13B-PTPRA_PPP1R13B_chr14_104313636_ENST00000202556_PTPRA_chr20_2985702_ENST00000318266_length(transcript)=2504nt_BP=292nt
GGGCGGGCGGGCCGCAGGCTGTCGGGCTGGGGCTGAGGCTGAGGCTGAGGTTGAGGCGGCGGCGGCGGCGGCCGGGTGCCCGGGACAGCG
ACGCAGCGCGCCGGCGGCCGCGACAGGGCCAGCGAGAGCCCCGCAGCCCGCCGCAGCTGCCGCCTCGCCGCGGCCGGGCCGGAGAGCACG
GCGGCGGGAGCGCGGCCTTAGGAGGCGGCCGGAGCGGTGGGCACAGCTCGGCGCGGAGCGTCCTGTCAGGCGGCGGCCGAGGGCGTCGCG
GACTCTCCCCGCGATGATGCCGGCTCTCCCTGCATGTCCTATCCAGGCCACCTGTGAGGCTGCTTCCAAGGAGGAAAACAAGGAAAAAAA
TCGATATGTAAACATCTTGCCTTATGACCACTCTAGAGTCCACCTGACACCGGTTGAAGGGGTTCCAGATTCTGATTACATCAATGCTTC
ATTCATCAACGGCTACCAAGAAAAGAACAAATTCATTGCTGCACAAGGACCAAAAGAAGAAACGGTGAATGATTTCTGGCGGATGATCTG
GGAACAAAACACAGCCACCATCGTCATGGTTACCAACCTGAAGGAGAGAAAGGAGTGCAAGTGCGCCCAGTACTGGCCAGACCAAGGCTG
CTGGACCTATGGGAATATTCGGGTGTCTGTAGAGGATGTGACTGTCCTGGTGGACTACACAGTACGGAAGTTCTGCATCCAGCAGGTGGG
CGACATGACCAACAGAAAGCCACAGCGCCTCATCACTCAGTTCCACTTTACCAGCTGGCCAGACTTTGGGGTGCCTTTTACCCCGATCGG
CATGCTCAAGTTCCTCAAGAAGGTGAAGGCCTGTAACCCTCAGTATGCAGGGGCCATCGTGGTCCACTGCAGTGCAGGTGTAGGGCGTAC
AGGTACCTTTGTCGTCATTGATGCCATGCTGGACATGATGCATACAGAACGGAAGGTGGACGTGTATGGCTTTGTGAGCCGGATCCGGGC
ACAGCGCTGCCAGATGGTGCAAACCGATATGCAGTATGTCTTCATATACCAAGCCCTTCTGGAGCATTATCTCTATGGAGATACAGAACT
GGAAGTGACCTCTCTAGAAACCCACCTGCAGAAAATTTACAACAAAATCCCAGGGACCAGCAACAATGGATTAGAGGAGGAGTTTAAGAA
GTTAACATCAATCAAAATCCAGAATGACAAGATGCGGACTGGAAACCTTCCAGCCAACATGAAGAAGAACCGTGTTTTACAGATCATTCC
ATATGAATTCAACAGAGTGATCATTCCAGTTAAGCGGGGCGAAGAGAATACAGACTATGTGAACGCATCCTTTATTGATGGCTACCGGCA
GAAGGACTCCTATATCGCCAGCCAGGGCCCTCTTCTCCACACAATTGAGGACTTCTGGCGAATGATCTGGGAGTGGAAATCCTGCTCTAT
CGTGATGCTAACAGAACTGGAGGAGAGAGGCCAGGAGAAGTGTGCCCAGTACTGGCCATCTGATGGACTGGTGTCCTATGGAGATATTAC
AGTGGAACTGAAGAAGGAGGAGGAATGTGAGAGCTACACCGTCCGAGACCTCCTGGTCACCAACACCAGGGAGAATAAGAGCCGGCAGAT
CCGGCAGTTCCACTTCCATGGCTGGCCTGAAGTGGGCATCCCCAGTGACGGAAAGGGCATGATCAGCATCATCGCCGCCGTGCAGAAGCA
GCAGCAGCAGTCAGGGAACCACCCCATCACCGTGCACTGCAGCGCCGGGGCAGGAAGGACGGGGACCTTCTGTGCCCTGAGCACCGTCCT
GGAGCGTGTGAAAGCAGAGGGGATTTTGGATGTCTTCCAGACTGTCAAGAGCCTGCGGCTACAGAGGCCACACATGGTCCAGACACTGGA
ACAGTATGAGTTCTGCTACAAGGTGGTGCAGGAGTATATTGATGCATTCTCAGATTATGCCAACTTCAAGTAAGCGGCAACAAGGGTCCG
TGGACCAGGAGGATTGCCTTTAATATTTTGTAATATTCTGTTTTGTTAATATACCCCAAATTGTGTATATATCTTATAACTGTTTTAGAA
ATTGGTACATAGGCTTCTATTACCTATTAGGTGGAAATTTTATATGTAAATGTGTTAGCACTGATAGTCCTTTTTCCAATGTTTTATTGG
GGAATTAAATAGTGTGATGTTTGGATTGATATCGTGAAATCCTCAGCCGAGAAATTGGGCTGGATTGTGCTTTGGTTAATACATCTTTCC
CTAAAGAAGATAAACACAAAATCCATTCCAGGTAGCTCGGCACCAACTAAGAAAAAAAGCACAAAGTTCTCAGAGCTCTCGAGGAAAGTG
GTTGTCCCCGTACCACCATGCACTGTAAATATCCCTCCCCTCTCTCCCTGGTCCCCTCCCCCATCCCCACCACTGATATCATGGGGAGTA

>67814_67814_2_PPP1R13B-PTPRA_PPP1R13B_chr14_104313636_ENST00000202556_PTPRA_chr20_2985702_ENST00000318266_length(amino acids)=559AA_BP=3
MMPALPACPIQATCEAASKEENKEKNRYVNILPYDHSRVHLTPVEGVPDSDYINASFINGYQEKNKFIAAQGPKEETVNDFWRMIWEQNT
ATIVMVTNLKERKECKCAQYWPDQGCWTYGNIRVSVEDVTVLVDYTVRKFCIQQVGDMTNRKPQRLITQFHFTSWPDFGVPFTPIGMLKF
LKKVKACNPQYAGAIVVHCSAGVGRTGTFVVIDAMLDMMHTERKVDVYGFVSRIRAQRCQMVQTDMQYVFIYQALLEHYLYGDTELEVTS
LETHLQKIYNKIPGTSNNGLEEEFKKLTSIKIQNDKMRTGNLPANMKKNRVLQIIPYEFNRVIIPVKRGEENTDYVNASFIDGYRQKDSY
IASQGPLLHTIEDFWRMIWEWKSCSIVMLTELEERGQEKCAQYWPSDGLVSYGDITVELKKEEECESYTVRDLLVTNTRENKSRQIRQFH
FHGWPEVGIPSDGKGMISIIAAVQKQQQQSGNHPITVHCSAGAGRTGTFCALSTVLERVKAEGILDVFQTVKSLRLQRPHMVQTLEQYEF

--------------------------------------------------------------
>67814_67814_3_PPP1R13B-PTPRA_PPP1R13B_chr14_104313636_ENST00000202556_PTPRA_chr20_2985702_ENST00000356147_length(transcript)=2498nt_BP=292nt
GGGCGGGCGGGCCGCAGGCTGTCGGGCTGGGGCTGAGGCTGAGGCTGAGGTTGAGGCGGCGGCGGCGGCGGCCGGGTGCCCGGGACAGCG
ACGCAGCGCGCCGGCGGCCGCGACAGGGCCAGCGAGAGCCCCGCAGCCCGCCGCAGCTGCCGCCTCGCCGCGGCCGGGCCGGAGAGCACG
GCGGCGGGAGCGCGGCCTTAGGAGGCGGCCGGAGCGGTGGGCACAGCTCGGCGCGGAGCGTCCTGTCAGGCGGCGGCCGAGGGCGTCGCG
GACTCTCCCCGCGATGATGCCGGCTCTCCCTGCATGTCCTATCCAGGCCACCTGTGAGGCTGCTTCCAAGGAGGAAAACAAGGAAAAAAA
TCGATATGTAAACATCTTGCCTTATGACCACTCTAGAGTCCACCTGACACCGGTTGAAGGGGTTCCAGATTCTGATTACATCAATGCTTC
ATTCATCAACGGCTACCAAGAAAAGAACAAATTCATTGCTGCACAAGGACCAAAAGAAGAAACGGTGAATGATTTCTGGCGGATGATCTG
GGAACAAAACACAGCCACCATCGTCATGGTTACCAACCTGAAGGAGAGAAAGGAGTGCAAGTGCGCCCAGTACTGGCCAGACCAAGGCTG
CTGGACCTATGGGAATATTCGGGTGTCTGTAGAGGATGTGACTGTCCTGGTGGACTACACAGTACGGAAGTTCTGCATCCAGCAGGTGGG
CGACATGACCAACAGAAAGCCACAGCGCCTCATCACTCAGTTCCACTTTACCAGCTGGCCAGACTTTGGGGTGCCTTTTACCCCGATCGG
CATGCTCAAGTTCCTCAAGAAGGTGAAGGCCTGTAACCCTCAGTATGCAGGGGCCATCGTGGTCCACTGCAGTGCAGGTGTAGGGCGTAC
AGGTACCTTTGTCGTCATTGATGCCATGCTGGACATGATGCATACAGAACGGAAGGTGGACGTGTATGGCTTTGTGAGCCGGATCCGGGC
ACAGCGCTGCCAGATGGTGCAAACCGATATGCAGTATGTCTTCATATACCAAGCCCTTCTGGAGCATTATCTCTATGGAGATACAGAACT
GGAAGTGACCTCTCTAGAAACCCACCTGCAGAAAATTTACAACAAAATCCCAGGGACCAGCAACAATGGATTAGAGGAGGAGTTTAAGAA
GTTAACATCAATCAAAATCCAGAATGACAAGATGCGGACTGGAAACCTTCCAGCCAACATGAAGAAGAACCGTGTTTTACAGATCATTCC
ATATGAATTCAACAGAGTGATCATTCCAGTTAAGCGGGGCGAAGAGAATACAGACTATGTGAACGCATCCTTTATTGATGGCTACCGGCA
GAAGGACTCCTATATCGCCAGCCAGGGCCCTCTTCTCCACACAATTGAGGACTTCTGGCGAATGATCTGGGAGTGGAAATCCTGCTCTAT
CGTGATGCTAACAGAACTGGAGGAGAGAGGCCAGGAGAAGTGTGCCCAGTACTGGCCATCTGATGGACTGGTGTCCTATGGAGATATTAC
AGTGGAACTGAAGAAGGAGGAGGAATGTGAGAGCTACACCGTCCGAGACCTCCTGGTCACCAACACCAGGGAGAATAAGAGCCGGCAGAT
CCGGCAGTTCCACTTCCATGGCTGGCCTGAAGTGGGCATCCCCAGTGACGGAAAGGGCATGATCAGCATCATCGCCGCCGTGCAGAAGCA
GCAGCAGCAGTCAGGGAACCACCCCATCACCGTGCACTGCAGCGCCGGGGCAGGAAGGACGGGGACCTTCTGTGCCCTGAGCACCGTCCT
GGAGCGTGTGAAAGCAGAGGGGATTTTGGATGTCTTCCAGACTGTCAAGAGCCTGCGGCTACAGAGGCCACACATGGTCCAGACACTGGA
ACAGTATGAGTTCTGCTACAAGGTGGTGCAGGAGTATATTGATGCATTCTCAGATTATGCCAACTTCAAGTAAGCGGCAACAAGGGTCCG
TGGACCAGGAGGATTGCCTTTAATATTTTGTAATATTCTGTTTTGTTAATATACCCCAAATTGTGTATATATCTTATAACTGTTTTAGAA
ATTGGTACATAGGCTTCTATTACCTATTAGGTGGAAATTTTATATGTAAATGTGTTAGCACTGATAGTCCTTTTTCCAATGTTTTATTGG
GGAATTAAATAGTGTGATGTTTGGATTGATATCGTGAAATCCTCAGCCGAGAAATTGGGCTGGATTGTGCTTTGGTTAATACATCTTTCC
CTAAAGAAGATAAACACAAAATCCATTCCAGGTAGCTCGGCACCAACTAAGAAAAAAAGCACAAAGTTCTCAGAGCTCTCGAGGAAAGTG
GTTGTCCCCGTACCACCATGCACTGTAAATATCCCTCCCCTCTCTCCCTGGTCCCCTCCCCCATCCCCACCACTGATATCATGGGGAGTA

>67814_67814_3_PPP1R13B-PTPRA_PPP1R13B_chr14_104313636_ENST00000202556_PTPRA_chr20_2985702_ENST00000356147_length(amino acids)=559AA_BP=3
MMPALPACPIQATCEAASKEENKEKNRYVNILPYDHSRVHLTPVEGVPDSDYINASFINGYQEKNKFIAAQGPKEETVNDFWRMIWEQNT
ATIVMVTNLKERKECKCAQYWPDQGCWTYGNIRVSVEDVTVLVDYTVRKFCIQQVGDMTNRKPQRLITQFHFTSWPDFGVPFTPIGMLKF
LKKVKACNPQYAGAIVVHCSAGVGRTGTFVVIDAMLDMMHTERKVDVYGFVSRIRAQRCQMVQTDMQYVFIYQALLEHYLYGDTELEVTS
LETHLQKIYNKIPGTSNNGLEEEFKKLTSIKIQNDKMRTGNLPANMKKNRVLQIIPYEFNRVIIPVKRGEENTDYVNASFIDGYRQKDSY
IASQGPLLHTIEDFWRMIWEWKSCSIVMLTELEERGQEKCAQYWPSDGLVSYGDITVELKKEEECESYTVRDLLVTNTRENKSRQIRQFH
FHGWPEVGIPSDGKGMISIIAAVQKQQQQSGNHPITVHCSAGAGRTGTFCALSTVLERVKAEGILDVFQTVKSLRLQRPHMVQTLEQYEF

--------------------------------------------------------------
>67814_67814_4_PPP1R13B-PTPRA_PPP1R13B_chr14_104313636_ENST00000202556_PTPRA_chr20_2985702_ENST00000358719_length(transcript)=2498nt_BP=292nt
GGGCGGGCGGGCCGCAGGCTGTCGGGCTGGGGCTGAGGCTGAGGCTGAGGTTGAGGCGGCGGCGGCGGCGGCCGGGTGCCCGGGACAGCG
ACGCAGCGCGCCGGCGGCCGCGACAGGGCCAGCGAGAGCCCCGCAGCCCGCCGCAGCTGCCGCCTCGCCGCGGCCGGGCCGGAGAGCACG
GCGGCGGGAGCGCGGCCTTAGGAGGCGGCCGGAGCGGTGGGCACAGCTCGGCGCGGAGCGTCCTGTCAGGCGGCGGCCGAGGGCGTCGCG
GACTCTCCCCGCGATGATGCCGGCTCTCCCTGCATGTCCTATCCAGGCCACCTGTGAGGCTGCTTCCAAGGAGGAAAACAAGGAAAAAAA
TCGATATGTAAACATCTTGCCTTATGACCACTCTAGAGTCCACCTGACACCGGTTGAAGGGGTTCCAGATTCTGATTACATCAATGCTTC
ATTCATCAACGGCTACCAAGAAAAGAACAAATTCATTGCTGCACAAGGACCAAAAGAAGAAACGGTGAATGATTTCTGGCGGATGATCTG
GGAACAAAACACAGCCACCATCGTCATGGTTACCAACCTGAAGGAGAGAAAGGAGTGCAAGTGCGCCCAGTACTGGCCAGACCAAGGCTG
CTGGACCTATGGGAATATTCGGGTGTCTGTAGAGGATGTGACTGTCCTGGTGGACTACACAGTACGGAAGTTCTGCATCCAGCAGGTGGG
CGACATGACCAACAGAAAGCCACAGCGCCTCATCACTCAGTTCCACTTTACCAGCTGGCCAGACTTTGGGGTGCCTTTTACCCCGATCGG
CATGCTCAAGTTCCTCAAGAAGGTGAAGGCCTGTAACCCTCAGTATGCAGGGGCCATCGTGGTCCACTGCAGTGCAGGTGTAGGGCGTAC
AGGTACCTTTGTCGTCATTGATGCCATGCTGGACATGATGCATACAGAACGGAAGGTGGACGTGTATGGCTTTGTGAGCCGGATCCGGGC
ACAGCGCTGCCAGATGGTGCAAACCGATATGCAGTATGTCTTCATATACCAAGCCCTTCTGGAGCATTATCTCTATGGAGATACAGAACT
GGAAGTGACCTCTCTAGAAACCCACCTGCAGAAAATTTACAACAAAATCCCAGGGACCAGCAACAATGGATTAGAGGAGGAGTTTAAGAA
GTTAACATCAATCAAAATCCAGAATGACAAGATGCGGACTGGAAACCTTCCAGCCAACATGAAGAAGAACCGTGTTTTACAGATCATTCC
ATATGAATTCAACAGAGTGATCATTCCAGTTAAGCGGGGCGAAGAGAATACAGACTATGTGAACGCATCCTTTATTGATGGCTACCGGCA
GAAGGACTCCTATATCGCCAGCCAGGGCCCTCTTCTCCACACAATTGAGGACTTCTGGCGAATGATCTGGGAGTGGAAATCCTGCTCTAT
CGTGATGCTAACAGAACTGGAGGAGAGAGGCCAGGAGAAGTGTGCCCAGTACTGGCCATCTGATGGACTGGTGTCCTATGGAGATATTAC
AGTGGAACTGAAGAAGGAGGAGGAATGTGAGAGCTACACCGTCCGAGACCTCCTGGTCACCAACACCAGGGAGAATAAGAGCCGGCAGAT
CCGGCAGTTCCACTTCCATGGCTGGCCTGAAGTGGGCATCCCCAGTGACGGAAAGGGCATGATCAGCATCATCGCCGCCGTGCAGAAGCA
GCAGCAGCAGTCAGGGAACCACCCCATCACCGTGCACTGCAGCGCCGGGGCAGGAAGGACGGGGACCTTCTGTGCCCTGAGCACCGTCCT
GGAGCGTGTGAAAGCAGAGGGGATTTTGGATGTCTTCCAGACTGTCAAGAGCCTGCGGCTACAGAGGCCACACATGGTCCAGACACTGGA
ACAGTATGAGTTCTGCTACAAGGTGGTGCAGGAGTATATTGATGCATTCTCAGATTATGCCAACTTCAAGTAAGCGGCAACAAGGGTCCG
TGGACCAGGAGGATTGCCTTTAATATTTTGTAATATTCTGTTTTGTTAATATACCCCAAATTGTGTATATATCTTATAACTGTTTTAGAA
ATTGGTACATAGGCTTCTATTACCTATTAGGTGGAAATTTTATATGTAAATGTGTTAGCACTGATAGTCCTTTTTCCAATGTTTTATTGG
GGAATTAAATAGTGTGATGTTTGGATTGATATCGTGAAATCCTCAGCCGAGAAATTGGGCTGGATTGTGCTTTGGTTAATACATCTTTCC
CTAAAGAAGATAAACACAAAATCCATTCCAGGTAGCTCGGCACCAACTAAGAAAAAAAGCACAAAGTTCTCAGAGCTCTCGAGGAAAGTG
GTTGTCCCCGTACCACCATGCACTGTAAATATCCCTCCCCTCTCTCCCTGGTCCCCTCCCCCATCCCCACCACTGATATCATGGGGAGTA

>67814_67814_4_PPP1R13B-PTPRA_PPP1R13B_chr14_104313636_ENST00000202556_PTPRA_chr20_2985702_ENST00000358719_length(amino acids)=559AA_BP=3
MMPALPACPIQATCEAASKEENKEKNRYVNILPYDHSRVHLTPVEGVPDSDYINASFINGYQEKNKFIAAQGPKEETVNDFWRMIWEQNT
ATIVMVTNLKERKECKCAQYWPDQGCWTYGNIRVSVEDVTVLVDYTVRKFCIQQVGDMTNRKPQRLITQFHFTSWPDFGVPFTPIGMLKF
LKKVKACNPQYAGAIVVHCSAGVGRTGTFVVIDAMLDMMHTERKVDVYGFVSRIRAQRCQMVQTDMQYVFIYQALLEHYLYGDTELEVTS
LETHLQKIYNKIPGTSNNGLEEEFKKLTSIKIQNDKMRTGNLPANMKKNRVLQIIPYEFNRVIIPVKRGEENTDYVNASFIDGYRQKDSY
IASQGPLLHTIEDFWRMIWEWKSCSIVMLTELEERGQEKCAQYWPSDGLVSYGDITVELKKEEECESYTVRDLLVTNTRENKSRQIRQFH
FHGWPEVGIPSDGKGMISIIAAVQKQQQQSGNHPITVHCSAGAGRTGTFCALSTVLERVKAEGILDVFQTVKSLRLQRPHMVQTLEQYEF

--------------------------------------------------------------
>67814_67814_5_PPP1R13B-PTPRA_PPP1R13B_chr14_104313636_ENST00000202556_PTPRA_chr20_2985702_ENST00000380393_length(transcript)=2504nt_BP=292nt
GGGCGGGCGGGCCGCAGGCTGTCGGGCTGGGGCTGAGGCTGAGGCTGAGGTTGAGGCGGCGGCGGCGGCGGCCGGGTGCCCGGGACAGCG
ACGCAGCGCGCCGGCGGCCGCGACAGGGCCAGCGAGAGCCCCGCAGCCCGCCGCAGCTGCCGCCTCGCCGCGGCCGGGCCGGAGAGCACG
GCGGCGGGAGCGCGGCCTTAGGAGGCGGCCGGAGCGGTGGGCACAGCTCGGCGCGGAGCGTCCTGTCAGGCGGCGGCCGAGGGCGTCGCG
GACTCTCCCCGCGATGATGCCGGCTCTCCCTGCATGTCCTATCCAGGCCACCTGTGAGGCTGCTTCCAAGGAGGAAAACAAGGAAAAAAA
TCGATATGTAAACATCTTGCCTTATGACCACTCTAGAGTCCACCTGACACCGGTTGAAGGGGTTCCAGATTCTGATTACATCAATGCTTC
ATTCATCAACGGCTACCAAGAAAAGAACAAATTCATTGCTGCACAAGGACCAAAAGAAGAAACGGTGAATGATTTCTGGCGGATGATCTG
GGAACAAAACACAGCCACCATCGTCATGGTTACCAACCTGAAGGAGAGAAAGGAGTGCAAGTGCGCCCAGTACTGGCCAGACCAAGGCTG
CTGGACCTATGGGAATATTCGGGTGTCTGTAGAGGATGTGACTGTCCTGGTGGACTACACAGTACGGAAGTTCTGCATCCAGCAGGTGGG
CGACATGACCAACAGAAAGCCACAGCGCCTCATCACTCAGTTCCACTTTACCAGCTGGCCAGACTTTGGGGTGCCTTTTACCCCGATCGG
CATGCTCAAGTTCCTCAAGAAGGTGAAGGCCTGTAACCCTCAGTATGCAGGGGCCATCGTGGTCCACTGCAGTGCAGGTGTAGGGCGTAC
AGGTACCTTTGTCGTCATTGATGCCATGCTGGACATGATGCATACAGAACGGAAGGTGGACGTGTATGGCTTTGTGAGCCGGATCCGGGC
ACAGCGCTGCCAGATGGTGCAAACCGATATGCAGTATGTCTTCATATACCAAGCCCTTCTGGAGCATTATCTCTATGGAGATACAGAACT
GGAAGTGACCTCTCTAGAAACCCACCTGCAGAAAATTTACAACAAAATCCCAGGGACCAGCAACAATGGATTAGAGGAGGAGTTTAAGAA
GTTAACATCAATCAAAATCCAGAATGACAAGATGCGGACTGGAAACCTTCCAGCCAACATGAAGAAGAACCGTGTTTTACAGATCATTCC
ATATGAATTCAACAGAGTGATCATTCCAGTTAAGCGGGGCGAAGAGAATACAGACTATGTGAACGCATCCTTTATTGATGGCTACCGGCA
GAAGGACTCCTATATCGCCAGCCAGGGCCCTCTTCTCCACACAATTGAGGACTTCTGGCGAATGATCTGGGAGTGGAAATCCTGCTCTAT
CGTGATGCTAACAGAACTGGAGGAGAGAGGCCAGGAGAAGTGTGCCCAGTACTGGCCATCTGATGGACTGGTGTCCTATGGAGATATTAC
AGTGGAACTGAAGAAGGAGGAGGAATGTGAGAGCTACACCGTCCGAGACCTCCTGGTCACCAACACCAGGGAGAATAAGAGCCGGCAGAT
CCGGCAGTTCCACTTCCATGGCTGGCCTGAAGTGGGCATCCCCAGTGACGGAAAGGGCATGATCAGCATCATCGCCGCCGTGCAGAAGCA
GCAGCAGCAGTCAGGGAACCACCCCATCACCGTGCACTGCAGCGCCGGGGCAGGAAGGACGGGGACCTTCTGTGCCCTGAGCACCGTCCT
GGAGCGTGTGAAAGCAGAGGGGATTTTGGATGTCTTCCAGACTGTCAAGAGCCTGCGGCTACAGAGGCCACACATGGTCCAGACACTGGA
ACAGTATGAGTTCTGCTACAAGGTGGTGCAGGAGTATATTGATGCATTCTCAGATTATGCCAACTTCAAGTAAGCGGCAACAAGGGTCCG
TGGACCAGGAGGATTGCCTTTAATATTTTGTAATATTCTGTTTTGTTAATATACCCCAAATTGTGTATATATCTTATAACTGTTTTAGAA
ATTGGTACATAGGCTTCTATTACCTATTAGGTGGAAATTTTATATGTAAATGTGTTAGCACTGATAGTCCTTTTTCCAATGTTTTATTGG
GGAATTAAATAGTGTGATGTTTGGATTGATATCGTGAAATCCTCAGCCGAGAAATTGGGCTGGATTGTGCTTTGGTTAATACATCTTTCC
CTAAAGAAGATAAACACAAAATCCATTCCAGGTAGCTCGGCACCAACTAAGAAAAAAAGCACAAAGTTCTCAGAGCTCTCGAGGAAAGTG
GTTGTCCCCGTACCACCATGCACTGTAAATATCCCTCCCCTCTCTCCCTGGTCCCCTCCCCCATCCCCACCACTGATATCATGGGGAGTA

>67814_67814_5_PPP1R13B-PTPRA_PPP1R13B_chr14_104313636_ENST00000202556_PTPRA_chr20_2985702_ENST00000380393_length(amino acids)=559AA_BP=3
MMPALPACPIQATCEAASKEENKEKNRYVNILPYDHSRVHLTPVEGVPDSDYINASFINGYQEKNKFIAAQGPKEETVNDFWRMIWEQNT
ATIVMVTNLKERKECKCAQYWPDQGCWTYGNIRVSVEDVTVLVDYTVRKFCIQQVGDMTNRKPQRLITQFHFTSWPDFGVPFTPIGMLKF
LKKVKACNPQYAGAIVVHCSAGVGRTGTFVVIDAMLDMMHTERKVDVYGFVSRIRAQRCQMVQTDMQYVFIYQALLEHYLYGDTELEVTS
LETHLQKIYNKIPGTSNNGLEEEFKKLTSIKIQNDKMRTGNLPANMKKNRVLQIIPYEFNRVIIPVKRGEENTDYVNASFIDGYRQKDSY
IASQGPLLHTIEDFWRMIWEWKSCSIVMLTELEERGQEKCAQYWPSDGLVSYGDITVELKKEEECESYTVRDLLVTNTRENKSRQIRQFH
FHGWPEVGIPSDGKGMISIIAAVQKQQQQSGNHPITVHCSAGAGRTGTFCALSTVLERVKAEGILDVFQTVKSLRLQRPHMVQTLEQYEF

--------------------------------------------------------------
>67814_67814_6_PPP1R13B-PTPRA_PPP1R13B_chr14_104313636_ENST00000202556_PTPRA_chr20_2985702_ENST00000399903_length(transcript)=2498nt_BP=292nt
GGGCGGGCGGGCCGCAGGCTGTCGGGCTGGGGCTGAGGCTGAGGCTGAGGTTGAGGCGGCGGCGGCGGCGGCCGGGTGCCCGGGACAGCG
ACGCAGCGCGCCGGCGGCCGCGACAGGGCCAGCGAGAGCCCCGCAGCCCGCCGCAGCTGCCGCCTCGCCGCGGCCGGGCCGGAGAGCACG
GCGGCGGGAGCGCGGCCTTAGGAGGCGGCCGGAGCGGTGGGCACAGCTCGGCGCGGAGCGTCCTGTCAGGCGGCGGCCGAGGGCGTCGCG
GACTCTCCCCGCGATGATGCCGGCTCTCCCTGCATGTCCTATCCAGGCCACCTGTGAGGCTGCTTCCAAGGAGGAAAACAAGGAAAAAAA
TCGATATGTAAACATCTTGCCTTATGACCACTCTAGAGTCCACCTGACACCGGTTGAAGGGGTTCCAGATTCTGATTACATCAATGCTTC
ATTCATCAACGGCTACCAAGAAAAGAACAAATTCATTGCTGCACAAGGACCAAAAGAAGAAACGGTGAATGATTTCTGGCGGATGATCTG
GGAACAAAACACAGCCACCATCGTCATGGTTACCAACCTGAAGGAGAGAAAGGAGTGCAAGTGCGCCCAGTACTGGCCAGACCAAGGCTG
CTGGACCTATGGGAATATTCGGGTGTCTGTAGAGGATGTGACTGTCCTGGTGGACTACACAGTACGGAAGTTCTGCATCCAGCAGGTGGG
CGACATGACCAACAGAAAGCCACAGCGCCTCATCACTCAGTTCCACTTTACCAGCTGGCCAGACTTTGGGGTGCCTTTTACCCCGATCGG
CATGCTCAAGTTCCTCAAGAAGGTGAAGGCCTGTAACCCTCAGTATGCAGGGGCCATCGTGGTCCACTGCAGTGCAGGTGTAGGGCGTAC
AGGTACCTTTGTCGTCATTGATGCCATGCTGGACATGATGCATACAGAACGGAAGGTGGACGTGTATGGCTTTGTGAGCCGGATCCGGGC
ACAGCGCTGCCAGATGGTGCAAACCGATATGCAGTATGTCTTCATATACCAAGCCCTTCTGGAGCATTATCTCTATGGAGATACAGAACT
GGAAGTGACCTCTCTAGAAACCCACCTGCAGAAAATTTACAACAAAATCCCAGGGACCAGCAACAATGGATTAGAGGAGGAGTTTAAGAA
GTTAACATCAATCAAAATCCAGAATGACAAGATGCGGACTGGAAACCTTCCAGCCAACATGAAGAAGAACCGTGTTTTACAGATCATTCC
ATATGAATTCAACAGAGTGATCATTCCAGTTAAGCGGGGCGAAGAGAATACAGACTATGTGAACGCATCCTTTATTGATGGCTACCGGCA
GAAGGACTCCTATATCGCCAGCCAGGGCCCTCTTCTCCACACAATTGAGGACTTCTGGCGAATGATCTGGGAGTGGAAATCCTGCTCTAT
CGTGATGCTAACAGAACTGGAGGAGAGAGGCCAGGAGAAGTGTGCCCAGTACTGGCCATCTGATGGACTGGTGTCCTATGGAGATATTAC
AGTGGAACTGAAGAAGGAGGAGGAATGTGAGAGCTACACCGTCCGAGACCTCCTGGTCACCAACACCAGGGAGAATAAGAGCCGGCAGAT
CCGGCAGTTCCACTTCCATGGCTGGCCTGAAGTGGGCATCCCCAGTGACGGAAAGGGCATGATCAGCATCATCGCCGCCGTGCAGAAGCA
GCAGCAGCAGTCAGGGAACCACCCCATCACCGTGCACTGCAGCGCCGGGGCAGGAAGGACGGGGACCTTCTGTGCCCTGAGCACCGTCCT
GGAGCGTGTGAAAGCAGAGGGGATTTTGGATGTCTTCCAGACTGTCAAGAGCCTGCGGCTACAGAGGCCACACATGGTCCAGACACTGGA
ACAGTATGAGTTCTGCTACAAGGTGGTGCAGGAGTATATTGATGCATTCTCAGATTATGCCAACTTCAAGTAAGCGGCAACAAGGGTCCG
TGGACCAGGAGGATTGCCTTTAATATTTTGTAATATTCTGTTTTGTTAATATACCCCAAATTGTGTATATATCTTATAACTGTTTTAGAA
ATTGGTACATAGGCTTCTATTACCTATTAGGTGGAAATTTTATATGTAAATGTGTTAGCACTGATAGTCCTTTTTCCAATGTTTTATTGG
GGAATTAAATAGTGTGATGTTTGGATTGATATCGTGAAATCCTCAGCCGAGAAATTGGGCTGGATTGTGCTTTGGTTAATACATCTTTCC
CTAAAGAAGATAAACACAAAATCCATTCCAGGTAGCTCGGCACCAACTAAGAAAAAAAGCACAAAGTTCTCAGAGCTCTCGAGGAAAGTG
GTTGTCCCCGTACCACCATGCACTGTAAATATCCCTCCCCTCTCTCCCTGGTCCCCTCCCCCATCCCCACCACTGATATCATGGGGAGTA

>67814_67814_6_PPP1R13B-PTPRA_PPP1R13B_chr14_104313636_ENST00000202556_PTPRA_chr20_2985702_ENST00000399903_length(amino acids)=559AA_BP=3
MMPALPACPIQATCEAASKEENKEKNRYVNILPYDHSRVHLTPVEGVPDSDYINASFINGYQEKNKFIAAQGPKEETVNDFWRMIWEQNT
ATIVMVTNLKERKECKCAQYWPDQGCWTYGNIRVSVEDVTVLVDYTVRKFCIQQVGDMTNRKPQRLITQFHFTSWPDFGVPFTPIGMLKF
LKKVKACNPQYAGAIVVHCSAGVGRTGTFVVIDAMLDMMHTERKVDVYGFVSRIRAQRCQMVQTDMQYVFIYQALLEHYLYGDTELEVTS
LETHLQKIYNKIPGTSNNGLEEEFKKLTSIKIQNDKMRTGNLPANMKKNRVLQIIPYEFNRVIIPVKRGEENTDYVNASFIDGYRQKDSY
IASQGPLLHTIEDFWRMIWEWKSCSIVMLTELEERGQEKCAQYWPSDGLVSYGDITVELKKEEECESYTVRDLLVTNTRENKSRQIRQFH
FHGWPEVGIPSDGKGMISIIAAVQKQQQQSGNHPITVHCSAGAGRTGTFCALSTVLERVKAEGILDVFQTVKSLRLQRPHMVQTLEQYEF

--------------------------------------------------------------
>67814_67814_7_PPP1R13B-PTPRA_PPP1R13B_chr14_104313636_ENST00000202556_PTPRA_chr20_2985702_ENST00000425918_length(transcript)=2209nt_BP=292nt
GGGCGGGCGGGCCGCAGGCTGTCGGGCTGGGGCTGAGGCTGAGGCTGAGGTTGAGGCGGCGGCGGCGGCGGCCGGGTGCCCGGGACAGCG
ACGCAGCGCGCCGGCGGCCGCGACAGGGCCAGCGAGAGCCCCGCAGCCCGCCGCAGCTGCCGCCTCGCCGCGGCCGGGCCGGAGAGCACG
GCGGCGGGAGCGCGGCCTTAGGAGGCGGCCGGAGCGGTGGGCACAGCTCGGCGCGGAGCGTCCTGTCAGGCGGCGGCCGAGGGCGTCGCG
GACTCTCCCCGCGATGATGCCGGCTCTCCCTGCATGTCCTATCCAGGCCACCTGTGAGGCTGCTTCCAAGGAGGAAAACAAGGAAAAAAA
TCGATATGTAAACATCTTGCCTTATGACCACTCTAGAGTCCACCTGACACCGGTTGAAGGGGTTCCAGATTCTGATTACATCAATGCTTC
ATTCATCAACGGCTACCAAGAAAAGAACAAATTCATTGCTGCACAAGGACCAAAAGAAGAAACGGTGAATGATTTCTGGCGGATGATCTG
GGAACAAAACACAGCCACCATCGTCATGGTTACCAACCTGAAGGAGAGAAAGGAGTGCAAGTGCGCCCAGTACTGGCCAGACCAAGGCTG
CTGGACCTATGGGAATATTCGGGTGTCTGTAGAGGATGTGACTGTCCTGGTGGACTACACAGTACGGAAGTTCTGCATCCAGCAGGTGGG
CGACATGACCAACAGAAAGCCACAGCGCCTCATCACTCAGTTCCACTTTACCAGCTGGCCAGACTTTGGGGTGCCTTTTACCCCGATCGG
CATGCTCAAGTTCCTCAAGAAGGTGAAGGCCTGTAACCCTCAGTATGCAGGGGCCATCGTGGTCCACTGCAGTGCAGGTGTAGGGCGTAC
AGGTACCTTTGTCGTCATTGATGCCATGCTGGACATGATGCATACAGAACGGAAGGTGGACGTGTATGGCTTTGTGAGCCGGATCCGGGC
ACAGCGCTGCCAGATGGTGCAAACCGATATGCAGTATGTCTTCATATACCAAGCCCTTCTGGAGCATTATCTCTATGGAGATACAGAACT
GGAAGTGACCTCTCTAGAAACCCACCTGCAGAAAATTTACAACAAAATCCCAGGGACCAGCAACAATGGATTAGAGGAGGAGTTTAAGAA
GTTAACATCAATCAAAATCCAGAATGACAAGATGCGGACTGGAAACCTTCCAGCCAACATGAAGAAGAACCGTGTTTTACAGATCATTCC
ATATGAATTCAACAGAGTGATCATTCCAGTTAAGCGGGGCGAAGAGAATACAGACTATGTGAACGCATCCTTTATTGATGGCTACCGGCA
GAAGGACTCCTATATCGCCAGCCAGGGCCCTCTTCTCCACACAATTGAGGACTTCTGGCGAATGATCTGGGAGTGGAAATCCTGCTCTAT
CGTGATGCTAACAGAACTGGAGGAGAGAGGCCAGGAGAAGTGTGCCCAGTACTGGCCATCTGATGGACTGGTGTCCTATGGAGATATTAC
AGTGGAACTGAAGAAGGAGGAGGAATGTGAGAGCTACACCGTCCGAGACCTCCTGGTCACCAACACCAGGGAGAATAAGAGCCGGCAGAT
CCGGCAGTTCCACTTCCATGGCTGGCCTGAAGTGGGCATCCCCAGTGACGGAAAGGGCATGATCAGCATCATCGCCGCCGTGCAGAAGCA
GCAGCAGCAGTCAGGGAACCACCCCATCACCGTGCACTGCAGCGCCGGGGCAGGAAGGACGGGGACCTTCTGTGCCCTGAGCACCGTCCT
GGAGCGTGTGAAAGCAGAGGGGATTTTGGATGTCTTCCAGACTGTCAAGAGCCTGCGGCTACAGAGGCCACACATGGTCCAGACACTGGA
ACAGTATGAGTTCTGCTACAAGGTGGTGCAGGAGTATATTGATGCATTCTCAGATTATGCCAACTTCAAGTAAGCGGCAACAAGGGTCCG
TGGACCAGGAGGATTGCCTTTAATATTTTGTAATATTCTGTTTTGTTAATATACCCCAAATTGTGTATATATCTTATAACTGTTTTAGAA
ATTGGTACATAGGCTTCTATTACCTATTAGGTGGAAATTTTATATGTAAATGTGTTAGCACTGATAGTCCTTTTTCCAATGTTTTATTGG

>67814_67814_7_PPP1R13B-PTPRA_PPP1R13B_chr14_104313636_ENST00000202556_PTPRA_chr20_2985702_ENST00000425918_length(amino acids)=559AA_BP=3
MMPALPACPIQATCEAASKEENKEKNRYVNILPYDHSRVHLTPVEGVPDSDYINASFINGYQEKNKFIAAQGPKEETVNDFWRMIWEQNT
ATIVMVTNLKERKECKCAQYWPDQGCWTYGNIRVSVEDVTVLVDYTVRKFCIQQVGDMTNRKPQRLITQFHFTSWPDFGVPFTPIGMLKF
LKKVKACNPQYAGAIVVHCSAGVGRTGTFVVIDAMLDMMHTERKVDVYGFVSRIRAQRCQMVQTDMQYVFIYQALLEHYLYGDTELEVTS
LETHLQKIYNKIPGTSNNGLEEEFKKLTSIKIQNDKMRTGNLPANMKKNRVLQIIPYEFNRVIIPVKRGEENTDYVNASFIDGYRQKDSY
IASQGPLLHTIEDFWRMIWEWKSCSIVMLTELEERGQEKCAQYWPSDGLVSYGDITVELKKEEECESYTVRDLLVTNTRENKSRQIRQFH
FHGWPEVGIPSDGKGMISIIAAVQKQQQQSGNHPITVHCSAGAGRTGTFCALSTVLERVKAEGILDVFQTVKSLRLQRPHMVQTLEQYEF

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Fusion Gene PPI Analysis for PPP1R13B-PTPRA


check button Go to ChiPPI (Chimeric Protein-Protein interactions) to see the chimeric PPI interaction in

ChiPPI page.


check button Protein-protein interactors with each fusion partner protein in wild-type (BIOGRID-3.4.160)
HgeneHgene's interactorsTgeneTgene's interactors


check button - Retained PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenStill interaction with


check button - Lost PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


check button - Retained PPIs, but lost function due to frame-shift fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


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Related Drugs for PPP1R13B-PTPRA


check button Drugs targeting genes involved in this fusion gene.
(DrugBank Version 5.1.8 2021-05-08)
PartnerGeneUniProtAccDrugBank IDDrug nameDrug activityDrug typeDrug status

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Related Diseases for PPP1R13B-PTPRA


check button Diseases associated with fusion partners.
(DisGeNet 4.0)
PartnerGeneDisease IDDisease name# pubmedsSource