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Center for Computational Systems Medicine
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Fusion Gene Summary

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Fusion Gene ORF analysis

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Fusion Genomic Features

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Fusion Protein Features

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Fusion Gene Sequence

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Fusion Gene PPI analysis

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Related Drugs

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Related Diseases

Fusion gene:PPP2R2B-DOCK2 (FusionGDB2 ID:68013)

Fusion Gene Summary for PPP2R2B-DOCK2

check button Fusion gene summary
Fusion gene informationFusion gene name: PPP2R2B-DOCK2
Fusion gene ID: 68013
HgeneTgene
Gene symbol

PPP2R2B

DOCK2

Gene ID

5521

1794

Gene nameprotein phosphatase 2 regulatory subunit Bbetadedicator of cytokinesis 2
SynonymsB55BETA|PP2AB55BETA|PP2ABBETA|PP2APR55B|PP2APR55BETA|PR2AB55BETA|PR2ABBETA|PR2APR55BETA|PR52B|PR55-BETA|PR55BETA|SCA12IMD40
Cytomap

5q32

5q35.1

Type of geneprotein-codingprotein-coding
Descriptionserine/threonine-protein phosphatase 2A 55 kDa regulatory subunit B beta isoformPP2A subunit B isoform B55-betaPP2A subunit B isoform PR55-betaPP2A subunit B isoform R2-betaPP2A, subunit B, B-beta isoformprotein phosphatase 2 (formerly 2A), regulatordedicator of cytokinesis protein 2dedicator of cyto-kinesis 2
Modification date2020032920200313
UniProtAcc.

Q92608

Ensembl transtripts involved in fusion geneENST00000356826, ENST00000394409, 
ENST00000394411, ENST00000394413, 
ENST00000394414, ENST00000453001, 
ENST00000530902, ENST00000336640, 
ENST00000394410, ENST00000504198, 
ENST00000508545, 		ENST00000523351, 
ENST00000256935, ENST00000520908, 
ENST00000540750, 
Fusion gene scores* DoF score9 X 7 X 5=31513 X 12 X 8=1248
# samples 1115
** MAII scorelog2(11/315*10)=-1.51784830486262
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0		log2(15/1248*10)=-3.05658352836637
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0
Context

PubMed: PPP2R2B [Title/Abstract] AND DOCK2 [Title/Abstract] AND fusion [Title/Abstract]

Most frequent breakpointPPP2R2B(146257565)-DOCK2(169435501), # samples:1
Anticipated loss of major functional domain due to fusion event.PPP2R2B-DOCK2 seems lost the major protein functional domain in Hgene partner, which is a essential gene due to the frame-shifted ORF.
PPP2R2B-DOCK2 seems lost the major protein functional domain in Tgene partner, which is a essential gene due to the frame-shifted ORF.
* DoF score (Degree of Frequency) = # partners X # break points X # cancer types
** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10)

check button Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez
PartnerGeneGO IDGO termPubMed ID

check buttonFusion gene breakpoints across PPP2R2B (5'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.
all structure

check buttonFusion gene breakpoints across DOCK2 (3'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.
all structure

check button Fusion gene information from two resources (ChiTars 5.0 and ChimerDB 4.0)
* All genome coordinats were lifted-over on hg19.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
SourceDiseaseSampleHgeneHchrHbpHstrandTgeneTchrTbpTstrand
ChimerDB4KIRCTCGA-BP-4173-01APPP2R2Bchr5

146257565

-DOCK2chr5

169435501

+


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Fusion Gene ORF analysis for PPP2R2B-DOCK2

check button Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
ORFHenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrand
5CDS-3UTRENST00000356826ENST00000523351PPP2R2Bchr5

146257565

-DOCK2chr5

169435501

+
5CDS-3UTRENST00000394409ENST00000523351PPP2R2Bchr5

146257565

-DOCK2chr5

169435501

+
5CDS-3UTRENST00000394411ENST00000523351PPP2R2Bchr5

146257565

-DOCK2chr5

169435501

+
5CDS-3UTRENST00000394413ENST00000523351PPP2R2Bchr5

146257565

-DOCK2chr5

169435501

+
5CDS-3UTRENST00000394414ENST00000523351PPP2R2Bchr5

146257565

-DOCK2chr5

169435501

+
5CDS-3UTRENST00000453001ENST00000523351PPP2R2Bchr5

146257565

-DOCK2chr5

169435501

+
5UTR-3CDSENST00000530902ENST00000256935PPP2R2Bchr5

146257565

-DOCK2chr5

169435501

+
5UTR-3CDSENST00000530902ENST00000520908PPP2R2Bchr5

146257565

-DOCK2chr5

169435501

+
5UTR-3CDSENST00000530902ENST00000540750PPP2R2Bchr5

146257565

-DOCK2chr5

169435501

+
5UTR-3UTRENST00000530902ENST00000523351PPP2R2Bchr5

146257565

-DOCK2chr5

169435501

+
Frame-shiftENST00000394409ENST00000256935PPP2R2Bchr5

146257565

-DOCK2chr5

169435501

+
Frame-shiftENST00000394409ENST00000520908PPP2R2Bchr5

146257565

-DOCK2chr5

169435501

+
Frame-shiftENST00000394409ENST00000540750PPP2R2Bchr5

146257565

-DOCK2chr5

169435501

+
Frame-shiftENST00000394411ENST00000256935PPP2R2Bchr5

146257565

-DOCK2chr5

169435501

+
Frame-shiftENST00000394411ENST00000520908PPP2R2Bchr5

146257565

-DOCK2chr5

169435501

+
Frame-shiftENST00000394411ENST00000540750PPP2R2Bchr5

146257565

-DOCK2chr5

169435501

+
Frame-shiftENST00000394414ENST00000256935PPP2R2Bchr5

146257565

-DOCK2chr5

169435501

+
Frame-shiftENST00000394414ENST00000520908PPP2R2Bchr5

146257565

-DOCK2chr5

169435501

+
Frame-shiftENST00000394414ENST00000540750PPP2R2Bchr5

146257565

-DOCK2chr5

169435501

+
In-frameENST00000356826ENST00000256935PPP2R2Bchr5

146257565

-DOCK2chr5

169435501

+
In-frameENST00000356826ENST00000520908PPP2R2Bchr5

146257565

-DOCK2chr5

169435501

+
In-frameENST00000356826ENST00000540750PPP2R2Bchr5

146257565

-DOCK2chr5

169435501

+
In-frameENST00000394413ENST00000256935PPP2R2Bchr5

146257565

-DOCK2chr5

169435501

+
In-frameENST00000394413ENST00000520908PPP2R2Bchr5

146257565

-DOCK2chr5

169435501

+
In-frameENST00000394413ENST00000540750PPP2R2Bchr5

146257565

-DOCK2chr5

169435501

+
In-frameENST00000453001ENST00000256935PPP2R2Bchr5

146257565

-DOCK2chr5

169435501

+
In-frameENST00000453001ENST00000520908PPP2R2Bchr5

146257565

-DOCK2chr5

169435501

+
In-frameENST00000453001ENST00000540750PPP2R2Bchr5

146257565

-DOCK2chr5

169435501

+
intron-3CDSENST00000336640ENST00000256935PPP2R2Bchr5

146257565

-DOCK2chr5

169435501

+
intron-3CDSENST00000336640ENST00000520908PPP2R2Bchr5

146257565

-DOCK2chr5

169435501

+
intron-3CDSENST00000336640ENST00000540750PPP2R2Bchr5

146257565

-DOCK2chr5

169435501

+
intron-3CDSENST00000394410ENST00000256935PPP2R2Bchr5

146257565

-DOCK2chr5

169435501

+
intron-3CDSENST00000394410ENST00000520908PPP2R2Bchr5

146257565

-DOCK2chr5

169435501

+
intron-3CDSENST00000394410ENST00000540750PPP2R2Bchr5

146257565

-DOCK2chr5

169435501

+
intron-3CDSENST00000504198ENST00000256935PPP2R2Bchr5

146257565

-DOCK2chr5

169435501

+
intron-3CDSENST00000504198ENST00000520908PPP2R2Bchr5

146257565

-DOCK2chr5

169435501

+
intron-3CDSENST00000504198ENST00000540750PPP2R2Bchr5

146257565

-DOCK2chr5

169435501

+
intron-3CDSENST00000508545ENST00000256935PPP2R2Bchr5

146257565

-DOCK2chr5

169435501

+
intron-3CDSENST00000508545ENST00000520908PPP2R2Bchr5

146257565

-DOCK2chr5

169435501

+
intron-3CDSENST00000508545ENST00000540750PPP2R2Bchr5

146257565

-DOCK2chr5

169435501

+
intron-3UTRENST00000336640ENST00000523351PPP2R2Bchr5

146257565

-DOCK2chr5

169435501

+
intron-3UTRENST00000394410ENST00000523351PPP2R2Bchr5

146257565

-DOCK2chr5

169435501

+
intron-3UTRENST00000504198ENST00000523351PPP2R2Bchr5

146257565

-DOCK2chr5

169435501

+
intron-3UTRENST00000508545ENST00000523351PPP2R2Bchr5

146257565

-DOCK2chr5

169435501

+

check buttonORFfinder result based on the fusion transcript sequence of in-frame fusion genes.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandSeq length
(transcript)		BP loci
(transcript)		Predicted start
(transcript)		Predicted stop
(transcript)		Seq length
(amino acids)
ENST00000394413PPP2R2Bchr5146257565-ENST00000256935DOCK2chr5169435501+35866415843061825
ENST00000394413PPP2R2Bchr5146257565-ENST00000540750DOCK2chr5169435501+35816415843061825
ENST00000394413PPP2R2Bchr5146257565-ENST00000520908DOCK2chr5169435501+35836415843061825
ENST00000453001PPP2R2Bchr5146257565-ENST00000256935DOCK2chr5169435501+33333883312808825
ENST00000453001PPP2R2Bchr5146257565-ENST00000540750DOCK2chr5169435501+33283883312808825
ENST00000453001PPP2R2Bchr5146257565-ENST00000520908DOCK2chr5169435501+33303883312808825
ENST00000356826PPP2R2Bchr5146257565-ENST00000256935DOCK2chr5169435501+36126676103087825
ENST00000356826PPP2R2Bchr5146257565-ENST00000540750DOCK2chr5169435501+36076676103087825
ENST00000356826PPP2R2Bchr5146257565-ENST00000520908DOCK2chr5169435501+36096676103087825

check buttonDeepORF prediction of the coding potential based on the fusion transcript sequence of in-frame fusion genes. DeepORF is a coding potential classifier based on convolutional neural network by comparing the real Ribo-seq data. If the no-coding score < 0.5 and coding score > 0.5, then the in-frame fusion transcript is predicted as being likely translated.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandNo-coding scoreCoding score
ENST00000394413ENST00000256935PPP2R2Bchr5146257565-DOCK2chr5169435501+0.0071499480.99285007
ENST00000394413ENST00000540750PPP2R2Bchr5146257565-DOCK2chr5169435501+0.0072856870.99271435
ENST00000394413ENST00000520908PPP2R2Bchr5146257565-DOCK2chr5169435501+0.007299060.99270093
ENST00000453001ENST00000256935PPP2R2Bchr5146257565-DOCK2chr5169435501+0.0077177450.9922822
ENST00000453001ENST00000540750PPP2R2Bchr5146257565-DOCK2chr5169435501+0.0078718050.99212825
ENST00000453001ENST00000520908PPP2R2Bchr5146257565-DOCK2chr5169435501+0.0078854060.9921146
ENST00000356826ENST00000256935PPP2R2Bchr5146257565-DOCK2chr5169435501+0.0049838880.99501616
ENST00000356826ENST00000540750PPP2R2Bchr5146257565-DOCK2chr5169435501+0.0051083240.99489164
ENST00000356826ENST00000520908PPP2R2Bchr5146257565-DOCK2chr5169435501+0.0051071910.99489284

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Fusion Genomic Features for PPP2R2B-DOCK2


check buttonFusionAI prediction of the potential fusion gene breakpoint based on the pre-mature RNA sequence context (+/- 5kb of individual partner genes, total 20kb length sequence). FusionAI is a fusion gene breakpoint classifier based on convolutional neural network by comparing the fusion positive and negative sequence context of ~ 20K fusion gene data. From here, we can have the relative potentency of the 20K genomic sequence how individual sequnce will be likely used as the gene fusion breakpoints.
HgeneHchrHbpHstrandTgeneTchrTbpTstrand1-pp (fusion gene breakpoint)
PPP2R2Bchr5146257564-DOCK2chr5169435500+0.000538290.9994617
PPP2R2Bchr5146257564-DOCK2chr5169435500+0.000538290.9994617

check buttonDistribution of 44 human genomic features loci across 20kb length fusion breakpoint regions. We integrated a total of 44 different types of human genomic feature loci information across five big categories including virus integration sites, repeats, structural variants, chromatin states, and gene expression regulation. More details are in help page.
genomic feature

check buttonDistribution of 44 human genomic features loci across 20kb length fusion breakpoint regions that are ovelapped with the top 1% feature importance score regions. More details are in help page.
genomic feature of top 1%

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Fusion Protein Features for PPP2R2B-DOCK2


check button Four levels of functional features of fusion genes
Go to FGviewer search page for the most frequent breakpoint (https://ccsmweb.uth.edu/FGviewer/chr5:146257565/chr5:169435501)
- FGviewer provides the online visualization of the retention search of the protein functional features across DNA, RNA, protein, and pathological levels.
- How to search
1. Put your fusion gene symbol.
2. Press the tab key until there will be shown the breakpoint information filled.
4. Go down and press 'Search' tab twice.
4. Go down to have the hyperlink of the search result.
5. Click the hyperlink.
6. See the FGviewer result for your fusion gene.
FGviewer

check buttonMain function of each fusion partner protein. (from UniProt)
HgeneTgene
.DOCK2

Q92608

FUNCTION: Transcriptional activator which is required for calcium-dependent dendritic growth and branching in cortical neurons. Recruits CREB-binding protein (CREBBP) to nuclear bodies. Component of the CREST-BRG1 complex, a multiprotein complex that regulates promoter activation by orchestrating a calcium-dependent release of a repressor complex and a recruitment of an activator complex. In resting neurons, transcription of the c-FOS promoter is inhibited by BRG1-dependent recruitment of a phospho-RB1-HDAC1 repressor complex. Upon calcium influx, RB1 is dephosphorylated by calcineurin, which leads to release of the repressor complex. At the same time, there is increased recruitment of CREBBP to the promoter by a CREST-dependent mechanism, which leads to transcriptional activation. The CREST-BRG1 complex also binds to the NR2B promoter, and activity-dependent induction of NR2B expression involves a release of HDAC1 and recruitment of CREBBP (By similarity). {ECO:0000250}.FUNCTION: Involved in cytoskeletal rearrangements required for lymphocyte migration in response of chemokines. Activates RAC1 and RAC2, but not CDC42, by functioning as a guanine nucleotide exchange factor (GEF), which exchanges bound GDP for free GTP. May also participate in IL2 transcriptional activation via the activation of RAC2. {ECO:0000269|PubMed:21613211}.

check buttonRetention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at

download page


* Minus value of BPloci means that the break pointn is located before the CDS.
- In-frame and retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
HgenePPP2R2Bchr5:146257565chr5:169435501ENST00000394409-21022_6181502.0RepeatNote=WD 1
HgenePPP2R2Bchr5:146257565chr5:169435501ENST00000394414-21022_6189510.0RepeatNote=WD 1
TgeneDOCK2chr5:146257565chr5:169435501ENST0000025693529521211_162210241831.0DomainDOCKER

- In-frame and not-retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
HgenePPP2R2Bchr5:146257565chr5:169435501ENST00000336640-19171_2090447.0RepeatNote=WD 3
HgenePPP2R2Bchr5:146257565chr5:169435501ENST00000336640-19220_2600447.0RepeatNote=WD 4
HgenePPP2R2Bchr5:146257565chr5:169435501ENST00000336640-1922_610447.0RepeatNote=WD 1
HgenePPP2R2Bchr5:146257565chr5:169435501ENST00000336640-19279_3170447.0RepeatNote=WD 5
HgenePPP2R2Bchr5:146257565chr5:169435501ENST00000336640-19334_3750447.0RepeatNote=WD 6
HgenePPP2R2Bchr5:146257565chr5:169435501ENST00000336640-19410_4420447.0RepeatNote=WD 7
HgenePPP2R2Bchr5:146257565chr5:169435501ENST00000336640-1987_1280447.0RepeatNote=WD 2
HgenePPP2R2Bchr5:146257565chr5:169435501ENST00000356826-210171_20923444.0RepeatNote=WD 3
HgenePPP2R2Bchr5:146257565chr5:169435501ENST00000356826-210220_26023444.0RepeatNote=WD 4
HgenePPP2R2Bchr5:146257565chr5:169435501ENST00000356826-21022_6123444.0RepeatNote=WD 1
HgenePPP2R2Bchr5:146257565chr5:169435501ENST00000356826-210279_31723444.0RepeatNote=WD 5
HgenePPP2R2Bchr5:146257565chr5:169435501ENST00000356826-210334_37523444.0RepeatNote=WD 6
HgenePPP2R2Bchr5:146257565chr5:169435501ENST00000356826-210410_44223444.0RepeatNote=WD 7
HgenePPP2R2Bchr5:146257565chr5:169435501ENST00000356826-21087_12823444.0RepeatNote=WD 2
HgenePPP2R2Bchr5:146257565chr5:169435501ENST00000394409-210171_20981502.0RepeatNote=WD 3
HgenePPP2R2Bchr5:146257565chr5:169435501ENST00000394409-210220_26081502.0RepeatNote=WD 4
HgenePPP2R2Bchr5:146257565chr5:169435501ENST00000394409-210279_31781502.0RepeatNote=WD 5
HgenePPP2R2Bchr5:146257565chr5:169435501ENST00000394409-210334_37581502.0RepeatNote=WD 6
HgenePPP2R2Bchr5:146257565chr5:169435501ENST00000394409-210410_44281502.0RepeatNote=WD 7
HgenePPP2R2Bchr5:146257565chr5:169435501ENST00000394409-21087_12881502.0RepeatNote=WD 2
HgenePPP2R2Bchr5:146257565chr5:169435501ENST00000394410-111171_2090433.0RepeatNote=WD 3
HgenePPP2R2Bchr5:146257565chr5:169435501ENST00000394410-111220_2600433.0RepeatNote=WD 4
HgenePPP2R2Bchr5:146257565chr5:169435501ENST00000394410-11122_610433.0RepeatNote=WD 1
HgenePPP2R2Bchr5:146257565chr5:169435501ENST00000394410-111279_3170433.0RepeatNote=WD 5
HgenePPP2R2Bchr5:146257565chr5:169435501ENST00000394410-111334_3750433.0RepeatNote=WD 6
HgenePPP2R2Bchr5:146257565chr5:169435501ENST00000394410-111410_4420433.0RepeatNote=WD 7
HgenePPP2R2Bchr5:146257565chr5:169435501ENST00000394410-11187_1280433.0RepeatNote=WD 2
HgenePPP2R2Bchr5:146257565chr5:169435501ENST00000394411-210171_20923444.0RepeatNote=WD 3
HgenePPP2R2Bchr5:146257565chr5:169435501ENST00000394411-210220_26023444.0RepeatNote=WD 4
HgenePPP2R2Bchr5:146257565chr5:169435501ENST00000394411-21022_6123444.0RepeatNote=WD 1
HgenePPP2R2Bchr5:146257565chr5:169435501ENST00000394411-210279_31723444.0RepeatNote=WD 5
HgenePPP2R2Bchr5:146257565chr5:169435501ENST00000394411-210334_37523444.0RepeatNote=WD 6
HgenePPP2R2Bchr5:146257565chr5:169435501ENST00000394411-210410_44223444.0RepeatNote=WD 7
HgenePPP2R2Bchr5:146257565chr5:169435501ENST00000394411-21087_12823444.0RepeatNote=WD 2
HgenePPP2R2Bchr5:146257565chr5:169435501ENST00000394413-19171_20923444.0RepeatNote=WD 3
HgenePPP2R2Bchr5:146257565chr5:169435501ENST00000394413-19220_26023444.0RepeatNote=WD 4
HgenePPP2R2Bchr5:146257565chr5:169435501ENST00000394413-1922_6123444.0RepeatNote=WD 1
HgenePPP2R2Bchr5:146257565chr5:169435501ENST00000394413-19279_31723444.0RepeatNote=WD 5
HgenePPP2R2Bchr5:146257565chr5:169435501ENST00000394413-19334_37523444.0RepeatNote=WD 6
HgenePPP2R2Bchr5:146257565chr5:169435501ENST00000394413-19410_44223444.0RepeatNote=WD 7
HgenePPP2R2Bchr5:146257565chr5:169435501ENST00000394413-1987_12823444.0RepeatNote=WD 2
HgenePPP2R2Bchr5:146257565chr5:169435501ENST00000394414-210171_20989510.0RepeatNote=WD 3
HgenePPP2R2Bchr5:146257565chr5:169435501ENST00000394414-210220_26089510.0RepeatNote=WD 4
HgenePPP2R2Bchr5:146257565chr5:169435501ENST00000394414-210279_31789510.0RepeatNote=WD 5
HgenePPP2R2Bchr5:146257565chr5:169435501ENST00000394414-210334_37589510.0RepeatNote=WD 6
HgenePPP2R2Bchr5:146257565chr5:169435501ENST00000394414-210410_44289510.0RepeatNote=WD 7
HgenePPP2R2Bchr5:146257565chr5:169435501ENST00000394414-21087_12889510.0RepeatNote=WD 2
HgenePPP2R2Bchr5:146257565chr5:169435501ENST00000453001-210171_20923444.0RepeatNote=WD 3
HgenePPP2R2Bchr5:146257565chr5:169435501ENST00000453001-210220_26023444.0RepeatNote=WD 4
HgenePPP2R2Bchr5:146257565chr5:169435501ENST00000453001-21022_6123444.0RepeatNote=WD 1
HgenePPP2R2Bchr5:146257565chr5:169435501ENST00000453001-210279_31723444.0RepeatNote=WD 5
HgenePPP2R2Bchr5:146257565chr5:169435501ENST00000453001-210334_37523444.0RepeatNote=WD 6
HgenePPP2R2Bchr5:146257565chr5:169435501ENST00000453001-210410_44223444.0RepeatNote=WD 7
HgenePPP2R2Bchr5:146257565chr5:169435501ENST00000453001-21087_12823444.0RepeatNote=WD 2
HgenePPP2R2Bchr5:146257565chr5:169435501ENST00000504198-110171_2090450.0RepeatNote=WD 3
HgenePPP2R2Bchr5:146257565chr5:169435501ENST00000504198-110220_2600450.0RepeatNote=WD 4
HgenePPP2R2Bchr5:146257565chr5:169435501ENST00000504198-11022_610450.0RepeatNote=WD 1
HgenePPP2R2Bchr5:146257565chr5:169435501ENST00000504198-110279_3170450.0RepeatNote=WD 5
HgenePPP2R2Bchr5:146257565chr5:169435501ENST00000504198-110334_3750450.0RepeatNote=WD 6
HgenePPP2R2Bchr5:146257565chr5:169435501ENST00000504198-110410_4420450.0RepeatNote=WD 7
HgenePPP2R2Bchr5:146257565chr5:169435501ENST00000504198-11087_1280450.0RepeatNote=WD 2
HgenePPP2R2Bchr5:146257565chr5:169435501ENST00000508545-110171_2090433.0RepeatNote=WD 3
HgenePPP2R2Bchr5:146257565chr5:169435501ENST00000508545-110220_2600433.0RepeatNote=WD 4
HgenePPP2R2Bchr5:146257565chr5:169435501ENST00000508545-11022_610433.0RepeatNote=WD 1
HgenePPP2R2Bchr5:146257565chr5:169435501ENST00000508545-110279_3170433.0RepeatNote=WD 5
HgenePPP2R2Bchr5:146257565chr5:169435501ENST00000508545-110334_3750433.0RepeatNote=WD 6
HgenePPP2R2Bchr5:146257565chr5:169435501ENST00000508545-110410_4420433.0RepeatNote=WD 7
HgenePPP2R2Bchr5:146257565chr5:169435501ENST00000508545-11087_1280433.0RepeatNote=WD 2
TgeneDOCK2chr5:146257565chr5:169435501ENST000002569352952423_60710241831.0DomainC2 DOCK-type
TgeneDOCK2chr5:146257565chr5:169435501ENST0000025693529528_6910241831.0DomainSH3


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Fusion Gene Sequence for PPP2R2B-DOCK2


check button For in-frame fusion transcripts, we provide the fusion transcript sequences and fusion amino acid sequences. To have fusion amino acid sequence, we ran ORFfinder and chose the longest ORF among the all predicted ones.
>68013_68013_1_PPP2R2B-DOCK2_PPP2R2B_chr5_146257565_ENST00000356826_DOCK2_chr5_169435501_ENST00000256935_length(transcript)=3612nt_BP=667nt
ATATCCTGCTGGATTTCTCTTGCGAAAAGAGAAACTCACCACACGGGAAAAGGTAGAGGTTTCAGGCAGAGCATTTCAGCGTGTGTTTAC
AGGCAGGACTGACTTACTCAGCAAATCCTGTTCAGAGGAGCTTCAGCCAATGAAGAGGCTATATCCCGGCTTGCTTGGGGGCTTCTGAGT
TTGAGCTGCATGCAGAAATGTAAGGCAGTGCTTCCTGGCGCTGATGGCAAAATGGGACCCATCTCCAGTTATTCCTCGGGCACCCCAGCT
TTGCAAATCTGGGAAAGAACCTACATAAACATATTGGTGATGTAGCCAGCTTAAAAGGCCGAGAGAATCCTTATGGATTCAGGAGACTGT
TTTTTTATTTAGATTTTTATTTTTTATTTGGAAGATGAAATGCTTCTCTCGTTACCTGCCTTACATCTTCAGACCTCCGAACACCATCCT
TTCTTCCAGCTGCCACACAGAAGGCTCGGACCATGGTGCAGTCCCACTGGCTCCCCTGCCCCCCTCTCCTGTGAGACTGGCTGCGGGGAG
GGATCATGGATACTTGTCTGCCGGCTTCTGGTTCCCACGCAAGTAAGCCTGCTGTCAATGGAGGAGGACATTGATACCCGCAAAATCAAC
AACAGTTTCCTGCGCGACCACAGCTATGCGACCGAAGCTGTGGAACAACTATTTTCATCTGGCAGTGGCTTTTATCACCCAGGATTCTCT
GCAGCTGGAGCAGTTCTCACACGCCAAATACAACAAAATCCTGAATAAGTATGGGGACATGAGACGGCTAATTGGCTTCTCCATCCGTGA
TATGTGGTACAAGCTTGGTCAGAACAAAATCTGCTTCATCCCAGGCATGGTAGGACCTATATTAGAGATGACACTTATCCCTGAGGCTGA
GCTCCGGAAAGCCACCATACCAATCTTCTTCGACATGATGCTGTGTGAATATCAAAGAAGTGGGGATTTCAAAAAGTTTGAAAACGAAAT
CATCCTGAAGCTGGACCACGAGGTAGAAGGGGGCCGAGGCGACGAGCAGTACATGCAGCTCCTGGAGTCAATCCTGATGGAATGTGCTGC
AGAGCACCCAACCATTGCCAAGTCGGTGGAGAACTTCGTGAACCTGGTCAAAGGCCTCCTGGAGAAGCTGCTGGATTACCGGGGTGTGAT
GACAGATGAGAGCAAAGACAACCGCATGAGCTGCACCGTGAACCTGCTGAATTTCTACAAAGATAACAACAGGGAGGAGATGTACATAAG
GTACCTGTACAAACTCCGCGATCTTCACCTGGACTGTGACAATTACACAGAGGCTGCCTACACGCTCCTTCTCCACACCTGGCTTCTCAA
GTGGTCGGATGAGCAGTGTGCATCACAGGTCATGCAGACAGGCCAGCAGCACCCCCAGACACACCGGCAGCTGAAGGAGACGCTCTACGA
GACCATCATAGGCTACTTTGACAAAGGAAAGATGTGGGAAGAGGCCATAAGTCTGTGCAAGGAGCTGGCGGAACAGTACGAGATGGAGAT
CTTTGACTATGAGCTGCTCAGCCAGAACCTGATCCAGCAGGCAAAATTCTATGAAAGCATCATGAAAATCCTCAGGCCCAAACCAGACTA
CTTTGCTGTTGGATACTACGGCCAGGGATTCCCCTCCTTCCTGCGGAACAAAGTGTTCATCTACCGCGGGAAGGAATATGAGCGAAGAGA
AGATTTCCAGATGCAGCTGATGACCCAGTTCCCCAATGCAGAGAAGATGAACACCACCTCTGCCCCGGGAGATGATGTGAAGAATGCCCC
AGGCCAGTATATCCAGTGCTTCACTGTCCAGCCTGTCTTGGATGAACATCCCAGGTTCAAGAATAAGCCAGTGCCTGACCAGATTATAAA
CTTCTACAAATCCAACTACGTGCAAAGGTTCCACTACTCCCGGCCCGTGCGCAGGGGGACCGTAGACCCAGAGAATGAGTTTGCTTCCAT
GTGGATTGAGAGAACCTCCTTCGTGACTGCATACAAGCTGCCGGGGATCCTGCGCTGGTTTGAGGTGGTGCACATGTCGCAGACCACAAT
TAGTCCTCTGGAGAATGCCATAGAAACCATGTCCACGGCCAATGAGAAGATCCTGATGATGATAAACCAGTACCAGAGTGATGAGACCCT
CCCCATCAACCCACTCTCCATGCTCCTGAACGGGATTGTGGACCCTGCTGTCATGGGAGGCTTCGCCAAGTATGAGAAGGCCTTCTTCAC
TGAAGAGTATGTCAGGGACCACCCTGAGGACCAGGACAAGCTGACCCACCTCAAGGACCTGATTGCATGGCAGATCCCCTTCTTGGGAGC
TGGGATTAAGATCCATGAGAAAAGGGTGTCAGATAACTTGCGACCCTTCCATGACCGGATGGAGGAATGTTTCAAGAACCTGAAAATGAA
GGTGGAGAAGGAGTACGGTGTCCGAGAGATGCCTGACTTTGACGACAGGAGAGTGGGCCGTCCCAGGTCTATGCTGCGCTCATACAGACA
GATGTCCATCATCTCTCTGGCTTCCATGAATTCTGACTGCAGCACCCCCAGCAAGCCTACCTCAGAGAGCTTTGACCTGGAATTAGCATC
ACCCAAGACGCCGAGAGTGGAGCAGGAGGAACCGATCTCCCCGGGGAGCACCCTGCCTGAGGTCAAGCTGCGGAGGTCCAAGAAGAGGAC
AAAGAGAAGCAGCGTAGTTTTTGCGGATGAGAAAGCAGCTGCAGAGTCGGACCTGAAGCGGCTTTCCAGGAAGCATGAGTTCATGAGTGA
CACCAACCTCTCGGAGCATGCGGCCATCCCCCTCAAGGCGTCTGTCCTCTCTCAAATGAGCTTTGCCAGCCAGTCCATGCCTACCATCCC
AGCCCTGGCGCTCTCAGTGGCAGGCATCCCTGGGTTGGATGAGGCCAACACATCTCCCCGCCTCAGCCAGACCTTCCTCCAACTCTCAGA
TGGTGACAAGAAGACACTCACACGGAAGAAGGTCAATCAGTTCTTCAAGACAATGCTGGCCAGCAAATCGGCTGAAGAAGGCAAACAGAT
CCCAGACTCGCTGTCCACGGACCTGTGAGCTGCTGCTGACTAGGGCTGCATGGGAGAGCCAGGGAGGGGAGTTTCTGGAAGAGGAAAGCC
ATGCGTGGAACATCGAAGCCTCAGAGAGTGGGAGACTGTCCCCATCAGTTGTCCTTACTTAGAGGAGACAGAGAGGCCAATCAGGTCCCA
GAGCTTGAATGCTAACAAGCCCAGCATCCCCTGGGGCTGTGATCATGGTGGATGAGGAAGCCTCAACGTAGATTCCTGAACTCAAGGTAC
CAGCAAGAATGCCTTCTCCCAGTGTGCTCTCCCCAACATCCTAGGCACAGCTTTCATAACCCAGTTTCTTAGGTGTAAGAAACTGTTTTT
ATCTCATTTATTAAGTCTCAGAACTTAACAGAAAAGGAAGCCTTTTAAATATTCTTTTTAATTTTATTTTAGATTAACAGTTTTGTACTT
TACATTTTTTTATACAACCAACCAGTTTCTTTTCTAGCCAATCATCTCTGAAGAGTTGCTGTTTCTTACTGACAATAAAAAATGTTCTCT

>68013_68013_1_PPP2R2B-DOCK2_PPP2R2B_chr5_146257565_ENST00000356826_DOCK2_chr5_169435501_ENST00000256935_length(amino acids)=825AA_BP=19
MIPAKSTTVSCATTAMRPKLWNNYFHLAVAFITQDSLQLEQFSHAKYNKILNKYGDMRRLIGFSIRDMWYKLGQNKICFIPGMVGPILEM
TLIPEAELRKATIPIFFDMMLCEYQRSGDFKKFENEIILKLDHEVEGGRGDEQYMQLLESILMECAAEHPTIAKSVENFVNLVKGLLEKL
LDYRGVMTDESKDNRMSCTVNLLNFYKDNNREEMYIRYLYKLRDLHLDCDNYTEAAYTLLLHTWLLKWSDEQCASQVMQTGQQHPQTHRQ
LKETLYETIIGYFDKGKMWEEAISLCKELAEQYEMEIFDYELLSQNLIQQAKFYESIMKILRPKPDYFAVGYYGQGFPSFLRNKVFIYRG
KEYERREDFQMQLMTQFPNAEKMNTTSAPGDDVKNAPGQYIQCFTVQPVLDEHPRFKNKPVPDQIINFYKSNYVQRFHYSRPVRRGTVDP
ENEFASMWIERTSFVTAYKLPGILRWFEVVHMSQTTISPLENAIETMSTANEKILMMINQYQSDETLPINPLSMLLNGIVDPAVMGGFAK
YEKAFFTEEYVRDHPEDQDKLTHLKDLIAWQIPFLGAGIKIHEKRVSDNLRPFHDRMEECFKNLKMKVEKEYGVREMPDFDDRRVGRPRS
MLRSYRQMSIISLASMNSDCSTPSKPTSESFDLELASPKTPRVEQEEPISPGSTLPEVKLRRSKKRTKRSSVVFADEKAAAESDLKRLSR
KHEFMSDTNLSEHAAIPLKASVLSQMSFASQSMPTIPALALSVAGIPGLDEANTSPRLSQTFLQLSDGDKKTLTRKKVNQFFKTMLASKS

--------------------------------------------------------------
>68013_68013_2_PPP2R2B-DOCK2_PPP2R2B_chr5_146257565_ENST00000356826_DOCK2_chr5_169435501_ENST00000520908_length(transcript)=3609nt_BP=667nt
ATATCCTGCTGGATTTCTCTTGCGAAAAGAGAAACTCACCACACGGGAAAAGGTAGAGGTTTCAGGCAGAGCATTTCAGCGTGTGTTTAC
AGGCAGGACTGACTTACTCAGCAAATCCTGTTCAGAGGAGCTTCAGCCAATGAAGAGGCTATATCCCGGCTTGCTTGGGGGCTTCTGAGT
TTGAGCTGCATGCAGAAATGTAAGGCAGTGCTTCCTGGCGCTGATGGCAAAATGGGACCCATCTCCAGTTATTCCTCGGGCACCCCAGCT
TTGCAAATCTGGGAAAGAACCTACATAAACATATTGGTGATGTAGCCAGCTTAAAAGGCCGAGAGAATCCTTATGGATTCAGGAGACTGT
TTTTTTATTTAGATTTTTATTTTTTATTTGGAAGATGAAATGCTTCTCTCGTTACCTGCCTTACATCTTCAGACCTCCGAACACCATCCT
TTCTTCCAGCTGCCACACAGAAGGCTCGGACCATGGTGCAGTCCCACTGGCTCCCCTGCCCCCCTCTCCTGTGAGACTGGCTGCGGGGAG
GGATCATGGATACTTGTCTGCCGGCTTCTGGTTCCCACGCAAGTAAGCCTGCTGTCAATGGAGGAGGACATTGATACCCGCAAAATCAAC
AACAGTTTCCTGCGCGACCACAGCTATGCGACCGAAGCTGTGGAACAACTATTTTCATCTGGCAGTGGCTTTTATCACCCAGGATTCTCT
GCAGCTGGAGCAGTTCTCACACGCCAAATACAACAAAATCCTGAATAAGTATGGGGACATGAGACGGCTAATTGGCTTCTCCATCCGTGA
TATGTGGTACAAGCTTGGTCAGAACAAAATCTGCTTCATCCCAGGCATGGTAGGACCTATATTAGAGATGACACTTATCCCTGAGGCTGA
GCTCCGGAAAGCCACCATACCAATCTTCTTCGACATGATGCTGTGTGAATATCAAAGAAGTGGGGATTTCAAAAAGTTTGAAAACGAAAT
CATCCTGAAGCTGGACCACGAGGTAGAAGGGGGCCGAGGCGACGAGCAGTACATGCAGCTCCTGGAGTCAATCCTGATGGAATGTGCTGC
AGAGCACCCAACCATTGCCAAGTCGGTGGAGAACTTCGTGAACCTGGTCAAAGGCCTCCTGGAGAAGCTGCTGGATTACCGGGGTGTGAT
GACAGATGAGAGCAAAGACAACCGCATGAGCTGCACCGTGAACCTGCTGAATTTCTACAAAGATAACAACAGGGAGGAGATGTACATAAG
GTACCTGTACAAACTCCGCGATCTTCACCTGGACTGTGACAATTACACAGAGGCTGCCTACACGCTCCTTCTCCACACCTGGCTTCTCAA
GTGGTCGGATGAGCAGTGTGCATCACAGGTCATGCAGACAGGCCAGCAGCACCCCCAGACACACCGGCAGCTGAAGGAGACGCTCTACGA
GACCATCATAGGCTACTTTGACAAAGGAAAGATGTGGGAAGAGGCCATAAGTCTGTGCAAGGAGCTGGCGGAACAGTACGAGATGGAGAT
CTTTGACTATGAGCTGCTCAGCCAGAACCTGATCCAGCAGGCAAAATTCTATGAAAGCATCATGAAAATCCTCAGGCCCAAACCAGACTA
CTTTGCTGTTGGATACTACGGCCAGGGATTCCCCTCCTTCCTGCGGAACAAAGTGTTCATCTACCGCGGGAAGGAATATGAGCGAAGAGA
AGATTTCCAGATGCAGCTGATGACCCAGTTCCCCAATGCAGAGAAGATGAACACCACCTCTGCCCCGGGAGATGATGTGAAGAATGCCCC
AGGCCAGTATATCCAGTGCTTCACTGTCCAGCCTGTCTTGGATGAACATCCCAGGTTCAAGAATAAGCCAGTGCCTGACCAGATTATAAA
CTTCTACAAATCCAACTACGTGCAAAGGTTCCACTACTCCCGGCCCGTGCGCAGGGGGACCGTAGACCCAGAGAATGAGTTTGCTTCCAT
GTGGATTGAGAGAACCTCCTTCGTGACTGCATACAAGCTGCCGGGGATCCTGCGCTGGTTTGAGGTGGTGCACATGTCGCAGACCACAAT
TAGTCCTCTGGAGAATGCCATAGAAACCATGTCCACGGCCAATGAGAAGATCCTGATGATGATAAACCAGTACCAGAGTGATGAGACCCT
CCCCATCAACCCACTCTCCATGCTCCTGAACGGGATTGTGGACCCTGCTGTCATGGGAGGCTTCGCCAAGTATGAGAAGGCCTTCTTCAC
TGAAGAGTATGTCAGGGACCACCCTGAGGACCAGGACAAGCTGACCCACCTCAAGGACCTGATTGCATGGCAGATCCCCTTCTTGGGAGC
TGGGATTAAGATCCATGAGAAAAGGGTGTCAGATAACTTGCGACCCTTCCATGACCGGATGGAGGAATGTTTCAAGAACCTGAAAATGAA
GGTGGAGAAGGAGTACGGTGTCCGAGAGATGCCTGACTTTGACGACAGGAGAGTGGGCCGTCCCAGGTCTATGCTGCGCTCATACAGACA
GATGTCCATCATCTCTCTGGCTTCCATGAATTCTGACTGCAGCACCCCCAGCAAGCCTACCTCAGAGAGCTTTGACCTGGAATTAGCATC
ACCCAAGACGCCGAGAGTGGAGCAGGAGGAACCGATCTCCCCGGGGAGCACCCTGCCTGAGGTCAAGCTGCGGAGGTCCAAGAAGAGGAC
AAAGAGAAGCAGCGTAGTTTTTGCGGATGAGAAAGCAGCTGCAGAGTCGGACCTGAAGCGGCTTTCCAGGAAGCATGAGTTCATGAGTGA
CACCAACCTCTCGGAGCATGCGGCCATCCCCCTCAAGGCGTCTGTCCTCTCTCAAATGAGCTTTGCCAGCCAGTCCATGCCTACCATCCC
AGCCCTGGCGCTCTCAGTGGCAGGCATCCCTGGGTTGGATGAGGCCAACACATCTCCCCGCCTCAGCCAGACCTTCCTCCAACTCTCAGA
TGGTGACAAGAAGACACTCACACGGAAGAAGGTCAATCAGTTCTTCAAGACAATGCTGGCCAGCAAATCGGCTGAAGAAGGCAAACAGAT
CCCAGACTCGCTGTCCACGGACCTGTGAGCTGCTGCTGACTAGGGCTGCATGGGAGAGCCAGGGAGGGGAGTTTCTGGAAGAGGAAAGCC
ATGCGTGGAACATCGAAGCCTCAGAGAGTGGGAGACTGTCCCCATCAGTTGTCCTTACTTAGAGGAGACAGAGAGGCCAATCAGGTCCCA
GAGCTTGAATGCTAACAAGCCCAGCATCCCCTGGGGCTGTGATCATGGTGGATGAGGAAGCCTCAACGTAGATTCCTGAACTCAAGGTAC
CAGCAAGAATGCCTTCTCCCAGTGTGCTCTCCCCAACATCCTAGGCACAGCTTTCATAACCCAGTTTCTTAGGTGTAAGAAACTGTTTTT
ATCTCATTTATTAAGTCTCAGAACTTAACAGAAAAGGAAGCCTTTTAAATATTCTTTTTAATTTTATTTTAGATTAACAGTTTTGTACTT
TACATTTTTTTATACAACCAACCAGTTTCTTTTCTAGCCAATCATCTCTGAAGAGTTGCTGTTTCTTACTGACAATAAAAAATGTTCTCT

>68013_68013_2_PPP2R2B-DOCK2_PPP2R2B_chr5_146257565_ENST00000356826_DOCK2_chr5_169435501_ENST00000520908_length(amino acids)=825AA_BP=19
MIPAKSTTVSCATTAMRPKLWNNYFHLAVAFITQDSLQLEQFSHAKYNKILNKYGDMRRLIGFSIRDMWYKLGQNKICFIPGMVGPILEM
TLIPEAELRKATIPIFFDMMLCEYQRSGDFKKFENEIILKLDHEVEGGRGDEQYMQLLESILMECAAEHPTIAKSVENFVNLVKGLLEKL
LDYRGVMTDESKDNRMSCTVNLLNFYKDNNREEMYIRYLYKLRDLHLDCDNYTEAAYTLLLHTWLLKWSDEQCASQVMQTGQQHPQTHRQ
LKETLYETIIGYFDKGKMWEEAISLCKELAEQYEMEIFDYELLSQNLIQQAKFYESIMKILRPKPDYFAVGYYGQGFPSFLRNKVFIYRG
KEYERREDFQMQLMTQFPNAEKMNTTSAPGDDVKNAPGQYIQCFTVQPVLDEHPRFKNKPVPDQIINFYKSNYVQRFHYSRPVRRGTVDP
ENEFASMWIERTSFVTAYKLPGILRWFEVVHMSQTTISPLENAIETMSTANEKILMMINQYQSDETLPINPLSMLLNGIVDPAVMGGFAK
YEKAFFTEEYVRDHPEDQDKLTHLKDLIAWQIPFLGAGIKIHEKRVSDNLRPFHDRMEECFKNLKMKVEKEYGVREMPDFDDRRVGRPRS
MLRSYRQMSIISLASMNSDCSTPSKPTSESFDLELASPKTPRVEQEEPISPGSTLPEVKLRRSKKRTKRSSVVFADEKAAAESDLKRLSR
KHEFMSDTNLSEHAAIPLKASVLSQMSFASQSMPTIPALALSVAGIPGLDEANTSPRLSQTFLQLSDGDKKTLTRKKVNQFFKTMLASKS

--------------------------------------------------------------
>68013_68013_3_PPP2R2B-DOCK2_PPP2R2B_chr5_146257565_ENST00000356826_DOCK2_chr5_169435501_ENST00000540750_length(transcript)=3607nt_BP=667nt
ATATCCTGCTGGATTTCTCTTGCGAAAAGAGAAACTCACCACACGGGAAAAGGTAGAGGTTTCAGGCAGAGCATTTCAGCGTGTGTTTAC
AGGCAGGACTGACTTACTCAGCAAATCCTGTTCAGAGGAGCTTCAGCCAATGAAGAGGCTATATCCCGGCTTGCTTGGGGGCTTCTGAGT
TTGAGCTGCATGCAGAAATGTAAGGCAGTGCTTCCTGGCGCTGATGGCAAAATGGGACCCATCTCCAGTTATTCCTCGGGCACCCCAGCT
TTGCAAATCTGGGAAAGAACCTACATAAACATATTGGTGATGTAGCCAGCTTAAAAGGCCGAGAGAATCCTTATGGATTCAGGAGACTGT
TTTTTTATTTAGATTTTTATTTTTTATTTGGAAGATGAAATGCTTCTCTCGTTACCTGCCTTACATCTTCAGACCTCCGAACACCATCCT
TTCTTCCAGCTGCCACACAGAAGGCTCGGACCATGGTGCAGTCCCACTGGCTCCCCTGCCCCCCTCTCCTGTGAGACTGGCTGCGGGGAG
GGATCATGGATACTTGTCTGCCGGCTTCTGGTTCCCACGCAAGTAAGCCTGCTGTCAATGGAGGAGGACATTGATACCCGCAAAATCAAC
AACAGTTTCCTGCGCGACCACAGCTATGCGACCGAAGCTGTGGAACAACTATTTTCATCTGGCAGTGGCTTTTATCACCCAGGATTCTCT
GCAGCTGGAGCAGTTCTCACACGCCAAATACAACAAAATCCTGAATAAGTATGGGGACATGAGACGGCTAATTGGCTTCTCCATCCGTGA
TATGTGGTACAAGCTTGGTCAGAACAAAATCTGCTTCATCCCAGGCATGGTAGGACCTATATTAGAGATGACACTTATCCCTGAGGCTGA
GCTCCGGAAAGCCACCATACCAATCTTCTTCGACATGATGCTGTGTGAATATCAAAGAAGTGGGGATTTCAAAAAGTTTGAAAACGAAAT
CATCCTGAAGCTGGACCACGAGGTAGAAGGGGGCCGAGGCGACGAGCAGTACATGCAGCTCCTGGAGTCAATCCTGATGGAATGTGCTGC
AGAGCACCCAACCATTGCCAAGTCGGTGGAGAACTTCGTGAACCTGGTCAAAGGCCTCCTGGAGAAGCTGCTGGATTACCGGGGTGTGAT
GACAGATGAGAGCAAAGACAACCGCATGAGCTGCACCGTGAACCTGCTGAATTTCTACAAAGATAACAACAGGGAGGAGATGTACATAAG
GTACCTGTACAAACTCCGCGATCTTCACCTGGACTGTGACAATTACACAGAGGCTGCCTACACGCTCCTTCTCCACACCTGGCTTCTCAA
GTGGTCGGATGAGCAGTGTGCATCACAGGTCATGCAGACAGGCCAGCAGCACCCCCAGACACACCGGCAGCTGAAGGAGACGCTCTACGA
GACCATCATAGGCTACTTTGACAAAGGAAAGATGTGGGAAGAGGCCATAAGTCTGTGCAAGGAGCTGGCGGAACAGTACGAGATGGAGAT
CTTTGACTATGAGCTGCTCAGCCAGAACCTGATCCAGCAGGCAAAATTCTATGAAAGCATCATGAAAATCCTCAGGCCCAAACCAGACTA
CTTTGCTGTTGGATACTACGGCCAGGGATTCCCCTCCTTCCTGCGGAACAAAGTGTTCATCTACCGCGGGAAGGAATATGAGCGAAGAGA
AGATTTCCAGATGCAGCTGATGACCCAGTTCCCCAATGCAGAGAAGATGAACACCACCTCTGCCCCGGGAGATGATGTGAAGAATGCCCC
AGGCCAGTATATCCAGTGCTTCACTGTCCAGCCTGTCTTGGATGAACATCCCAGGTTCAAGAATAAGCCAGTGCCTGACCAGATTATAAA
CTTCTACAAATCCAACTACGTGCAAAGGTTCCACTACTCCCGGCCCGTGCGCAGGGGGACCGTAGACCCAGAGAATGAGTTTGCTTCCAT
GTGGATTGAGAGAACCTCCTTCGTGACTGCATACAAGCTGCCGGGGATCCTGCGCTGGTTTGAGGTGGTGCACATGTCGCAGACCACAAT
TAGTCCTCTGGAGAATGCCATAGAAACCATGTCCACGGCCAATGAGAAGATCCTGATGATGATAAACCAGTACCAGAGTGATGAGACCCT
CCCCATCAACCCACTCTCCATGCTCCTGAACGGGATTGTGGACCCTGCTGTCATGGGAGGCTTCGCCAAGTATGAGAAGGCCTTCTTCAC
TGAAGAGTATGTCAGGGACCACCCTGAGGACCAGGACAAGCTGACCCACCTCAAGGACCTGATTGCATGGCAGATCCCCTTCTTGGGAGC
TGGGATTAAGATCCATGAGAAAAGGGTGTCAGATAACTTGCGACCCTTCCATGACCGGATGGAGGAATGTTTCAAGAACCTGAAAATGAA
GGTGGAGAAGGAGTACGGTGTCCGAGAGATGCCTGACTTTGACGACAGGAGAGTGGGCCGTCCCAGGTCTATGCTGCGCTCATACAGACA
GATGTCCATCATCTCTCTGGCTTCCATGAATTCTGACTGCAGCACCCCCAGCAAGCCTACCTCAGAGAGCTTTGACCTGGAATTAGCATC
ACCCAAGACGCCGAGAGTGGAGCAGGAGGAACCGATCTCCCCGGGGAGCACCCTGCCTGAGGTCAAGCTGCGGAGGTCCAAGAAGAGGAC
AAAGAGAAGCAGCGTAGTTTTTGCGGATGAGAAAGCAGCTGCAGAGTCGGACCTGAAGCGGCTTTCCAGGAAGCATGAGTTCATGAGTGA
CACCAACCTCTCGGAGCATGCGGCCATCCCCCTCAAGGCGTCTGTCCTCTCTCAAATGAGCTTTGCCAGCCAGTCCATGCCTACCATCCC
AGCCCTGGCGCTCTCAGTGGCAGGCATCCCTGGGTTGGATGAGGCCAACACATCTCCCCGCCTCAGCCAGACCTTCCTCCAACTCTCAGA
TGGTGACAAGAAGACACTCACACGGAAGAAGGTCAATCAGTTCTTCAAGACAATGCTGGCCAGCAAATCGGCTGAAGAAGGCAAACAGAT
CCCAGACTCGCTGTCCACGGACCTGTGAGCTGCTGCTGACTAGGGCTGCATGGGAGAGCCAGGGAGGGGAGTTTCTGGAAGAGGAAAGCC
ATGCGTGGAACATCGAAGCCTCAGAGAGTGGGAGACTGTCCCCATCAGTTGTCCTTACTTAGAGGAGACAGAGAGGCCAATCAGGTCCCA
GAGCTTGAATGCTAACAAGCCCAGCATCCCCTGGGGCTGTGATCATGGTGGATGAGGAAGCCTCAACGTAGATTCCTGAACTCAAGGTAC
CAGCAAGAATGCCTTCTCCCAGTGTGCTCTCCCCAACATCCTAGGCACAGCTTTCATAACCCAGTTTCTTAGGTGTAAGAAACTGTTTTT
ATCTCATTTATTAAGTCTCAGAACTTAACAGAAAAGGAAGCCTTTTAAATATTCTTTTTAATTTTATTTTAGATTAACAGTTTTGTACTT
TACATTTTTTTATACAACCAACCAGTTTCTTTTCTAGCCAATCATCTCTGAAGAGTTGCTGTTTCTTACTGACAATAAAAAATGTTCTCT

>68013_68013_3_PPP2R2B-DOCK2_PPP2R2B_chr5_146257565_ENST00000356826_DOCK2_chr5_169435501_ENST00000540750_length(amino acids)=825AA_BP=19
MIPAKSTTVSCATTAMRPKLWNNYFHLAVAFITQDSLQLEQFSHAKYNKILNKYGDMRRLIGFSIRDMWYKLGQNKICFIPGMVGPILEM
TLIPEAELRKATIPIFFDMMLCEYQRSGDFKKFENEIILKLDHEVEGGRGDEQYMQLLESILMECAAEHPTIAKSVENFVNLVKGLLEKL
LDYRGVMTDESKDNRMSCTVNLLNFYKDNNREEMYIRYLYKLRDLHLDCDNYTEAAYTLLLHTWLLKWSDEQCASQVMQTGQQHPQTHRQ
LKETLYETIIGYFDKGKMWEEAISLCKELAEQYEMEIFDYELLSQNLIQQAKFYESIMKILRPKPDYFAVGYYGQGFPSFLRNKVFIYRG
KEYERREDFQMQLMTQFPNAEKMNTTSAPGDDVKNAPGQYIQCFTVQPVLDEHPRFKNKPVPDQIINFYKSNYVQRFHYSRPVRRGTVDP
ENEFASMWIERTSFVTAYKLPGILRWFEVVHMSQTTISPLENAIETMSTANEKILMMINQYQSDETLPINPLSMLLNGIVDPAVMGGFAK
YEKAFFTEEYVRDHPEDQDKLTHLKDLIAWQIPFLGAGIKIHEKRVSDNLRPFHDRMEECFKNLKMKVEKEYGVREMPDFDDRRVGRPRS
MLRSYRQMSIISLASMNSDCSTPSKPTSESFDLELASPKTPRVEQEEPISPGSTLPEVKLRRSKKRTKRSSVVFADEKAAAESDLKRLSR
KHEFMSDTNLSEHAAIPLKASVLSQMSFASQSMPTIPALALSVAGIPGLDEANTSPRLSQTFLQLSDGDKKTLTRKKVNQFFKTMLASKS

--------------------------------------------------------------
>68013_68013_4_PPP2R2B-DOCK2_PPP2R2B_chr5_146257565_ENST00000394413_DOCK2_chr5_169435501_ENST00000256935_length(transcript)=3586nt_BP=641nt
CCCGCCTGCCGGAGCCGCCCTCCCGTGGGACCAGCACCCTCATTCCGGCCAGGCAAGCCTGAATCCTGTCCCTGCCATCTCGCCACTGCA
GCTCGGGTCCAGAAAGGCACCATTTTGTCGCGGCTGCCCGCTCTCCCAGGGGGAGGAGGGATCTTTTTTGCATTTTGGAGCGGCTGCCAA
GGAGGGGAACCTGTTGGGCATCTCCCCAGACCCGCTTGTGAGCGCCTCCGGGGCGGGCGGGCGGGACCAGACCCCTCGGGGCACGGCGTA
TCTTGGCACCCGGAGGCAGCGGAGGCAGGCGCAGCATCCTCGCTGGGAACTGGAGCTGGAGTGAGCGCACCGCGCGGGAGGAGCCGCCGC
AGCCTCGCAGAACCCGAGTGGAGGAGGTGACAGCTCCATTGCCGGGTTTTTATTTTTTTTCTCTCCGCCTCCCCGTCTCCTCCTCAGGCT
CGGACCATGGTGCAGTCCCACTGGCTCCCCTGCCCCCCTCTCCTGTGAGACTGGCTGCGGGGAGGGATCATGGATACTTGTCTGCCGGCT
TCTGGTTCCCACGCAAGTAAGCCTGCTGTCAATGGAGGAGGACATTGATACCCGCAAAATCAACAACAGTTTCCTGCGCGACCACAGCTA
TGCGACCGAAGCTGTGGAACAACTATTTTCATCTGGCAGTGGCTTTTATCACCCAGGATTCTCTGCAGCTGGAGCAGTTCTCACACGCCA
AATACAACAAAATCCTGAATAAGTATGGGGACATGAGACGGCTAATTGGCTTCTCCATCCGTGATATGTGGTACAAGCTTGGTCAGAACA
AAATCTGCTTCATCCCAGGCATGGTAGGACCTATATTAGAGATGACACTTATCCCTGAGGCTGAGCTCCGGAAAGCCACCATACCAATCT
TCTTCGACATGATGCTGTGTGAATATCAAAGAAGTGGGGATTTCAAAAAGTTTGAAAACGAAATCATCCTGAAGCTGGACCACGAGGTAG
AAGGGGGCCGAGGCGACGAGCAGTACATGCAGCTCCTGGAGTCAATCCTGATGGAATGTGCTGCAGAGCACCCAACCATTGCCAAGTCGG
TGGAGAACTTCGTGAACCTGGTCAAAGGCCTCCTGGAGAAGCTGCTGGATTACCGGGGTGTGATGACAGATGAGAGCAAAGACAACCGCA
TGAGCTGCACCGTGAACCTGCTGAATTTCTACAAAGATAACAACAGGGAGGAGATGTACATAAGGTACCTGTACAAACTCCGCGATCTTC
ACCTGGACTGTGACAATTACACAGAGGCTGCCTACACGCTCCTTCTCCACACCTGGCTTCTCAAGTGGTCGGATGAGCAGTGTGCATCAC
AGGTCATGCAGACAGGCCAGCAGCACCCCCAGACACACCGGCAGCTGAAGGAGACGCTCTACGAGACCATCATAGGCTACTTTGACAAAG
GAAAGATGTGGGAAGAGGCCATAAGTCTGTGCAAGGAGCTGGCGGAACAGTACGAGATGGAGATCTTTGACTATGAGCTGCTCAGCCAGA
ACCTGATCCAGCAGGCAAAATTCTATGAAAGCATCATGAAAATCCTCAGGCCCAAACCAGACTACTTTGCTGTTGGATACTACGGCCAGG
GATTCCCCTCCTTCCTGCGGAACAAAGTGTTCATCTACCGCGGGAAGGAATATGAGCGAAGAGAAGATTTCCAGATGCAGCTGATGACCC
AGTTCCCCAATGCAGAGAAGATGAACACCACCTCTGCCCCGGGAGATGATGTGAAGAATGCCCCAGGCCAGTATATCCAGTGCTTCACTG
TCCAGCCTGTCTTGGATGAACATCCCAGGTTCAAGAATAAGCCAGTGCCTGACCAGATTATAAACTTCTACAAATCCAACTACGTGCAAA
GGTTCCACTACTCCCGGCCCGTGCGCAGGGGGACCGTAGACCCAGAGAATGAGTTTGCTTCCATGTGGATTGAGAGAACCTCCTTCGTGA
CTGCATACAAGCTGCCGGGGATCCTGCGCTGGTTTGAGGTGGTGCACATGTCGCAGACCACAATTAGTCCTCTGGAGAATGCCATAGAAA
CCATGTCCACGGCCAATGAGAAGATCCTGATGATGATAAACCAGTACCAGAGTGATGAGACCCTCCCCATCAACCCACTCTCCATGCTCC
TGAACGGGATTGTGGACCCTGCTGTCATGGGAGGCTTCGCCAAGTATGAGAAGGCCTTCTTCACTGAAGAGTATGTCAGGGACCACCCTG
AGGACCAGGACAAGCTGACCCACCTCAAGGACCTGATTGCATGGCAGATCCCCTTCTTGGGAGCTGGGATTAAGATCCATGAGAAAAGGG
TGTCAGATAACTTGCGACCCTTCCATGACCGGATGGAGGAATGTTTCAAGAACCTGAAAATGAAGGTGGAGAAGGAGTACGGTGTCCGAG
AGATGCCTGACTTTGACGACAGGAGAGTGGGCCGTCCCAGGTCTATGCTGCGCTCATACAGACAGATGTCCATCATCTCTCTGGCTTCCA
TGAATTCTGACTGCAGCACCCCCAGCAAGCCTACCTCAGAGAGCTTTGACCTGGAATTAGCATCACCCAAGACGCCGAGAGTGGAGCAGG
AGGAACCGATCTCCCCGGGGAGCACCCTGCCTGAGGTCAAGCTGCGGAGGTCCAAGAAGAGGACAAAGAGAAGCAGCGTAGTTTTTGCGG
ATGAGAAAGCAGCTGCAGAGTCGGACCTGAAGCGGCTTTCCAGGAAGCATGAGTTCATGAGTGACACCAACCTCTCGGAGCATGCGGCCA
TCCCCCTCAAGGCGTCTGTCCTCTCTCAAATGAGCTTTGCCAGCCAGTCCATGCCTACCATCCCAGCCCTGGCGCTCTCAGTGGCAGGCA
TCCCTGGGTTGGATGAGGCCAACACATCTCCCCGCCTCAGCCAGACCTTCCTCCAACTCTCAGATGGTGACAAGAAGACACTCACACGGA
AGAAGGTCAATCAGTTCTTCAAGACAATGCTGGCCAGCAAATCGGCTGAAGAAGGCAAACAGATCCCAGACTCGCTGTCCACGGACCTGT
GAGCTGCTGCTGACTAGGGCTGCATGGGAGAGCCAGGGAGGGGAGTTTCTGGAAGAGGAAAGCCATGCGTGGAACATCGAAGCCTCAGAG
AGTGGGAGACTGTCCCCATCAGTTGTCCTTACTTAGAGGAGACAGAGAGGCCAATCAGGTCCCAGAGCTTGAATGCTAACAAGCCCAGCA
TCCCCTGGGGCTGTGATCATGGTGGATGAGGAAGCCTCAACGTAGATTCCTGAACTCAAGGTACCAGCAAGAATGCCTTCTCCCAGTGTG
CTCTCCCCAACATCCTAGGCACAGCTTTCATAACCCAGTTTCTTAGGTGTAAGAAACTGTTTTTATCTCATTTATTAAGTCTCAGAACTT
AACAGAAAAGGAAGCCTTTTAAATATTCTTTTTAATTTTATTTTAGATTAACAGTTTTGTACTTTACATTTTTTTATACAACCAACCAGT

>68013_68013_4_PPP2R2B-DOCK2_PPP2R2B_chr5_146257565_ENST00000394413_DOCK2_chr5_169435501_ENST00000256935_length(amino acids)=825AA_BP=19
MIPAKSTTVSCATTAMRPKLWNNYFHLAVAFITQDSLQLEQFSHAKYNKILNKYGDMRRLIGFSIRDMWYKLGQNKICFIPGMVGPILEM
TLIPEAELRKATIPIFFDMMLCEYQRSGDFKKFENEIILKLDHEVEGGRGDEQYMQLLESILMECAAEHPTIAKSVENFVNLVKGLLEKL
LDYRGVMTDESKDNRMSCTVNLLNFYKDNNREEMYIRYLYKLRDLHLDCDNYTEAAYTLLLHTWLLKWSDEQCASQVMQTGQQHPQTHRQ
LKETLYETIIGYFDKGKMWEEAISLCKELAEQYEMEIFDYELLSQNLIQQAKFYESIMKILRPKPDYFAVGYYGQGFPSFLRNKVFIYRG
KEYERREDFQMQLMTQFPNAEKMNTTSAPGDDVKNAPGQYIQCFTVQPVLDEHPRFKNKPVPDQIINFYKSNYVQRFHYSRPVRRGTVDP
ENEFASMWIERTSFVTAYKLPGILRWFEVVHMSQTTISPLENAIETMSTANEKILMMINQYQSDETLPINPLSMLLNGIVDPAVMGGFAK
YEKAFFTEEYVRDHPEDQDKLTHLKDLIAWQIPFLGAGIKIHEKRVSDNLRPFHDRMEECFKNLKMKVEKEYGVREMPDFDDRRVGRPRS
MLRSYRQMSIISLASMNSDCSTPSKPTSESFDLELASPKTPRVEQEEPISPGSTLPEVKLRRSKKRTKRSSVVFADEKAAAESDLKRLSR
KHEFMSDTNLSEHAAIPLKASVLSQMSFASQSMPTIPALALSVAGIPGLDEANTSPRLSQTFLQLSDGDKKTLTRKKVNQFFKTMLASKS

--------------------------------------------------------------
>68013_68013_5_PPP2R2B-DOCK2_PPP2R2B_chr5_146257565_ENST00000394413_DOCK2_chr5_169435501_ENST00000520908_length(transcript)=3583nt_BP=641nt
CCCGCCTGCCGGAGCCGCCCTCCCGTGGGACCAGCACCCTCATTCCGGCCAGGCAAGCCTGAATCCTGTCCCTGCCATCTCGCCACTGCA
GCTCGGGTCCAGAAAGGCACCATTTTGTCGCGGCTGCCCGCTCTCCCAGGGGGAGGAGGGATCTTTTTTGCATTTTGGAGCGGCTGCCAA
GGAGGGGAACCTGTTGGGCATCTCCCCAGACCCGCTTGTGAGCGCCTCCGGGGCGGGCGGGCGGGACCAGACCCCTCGGGGCACGGCGTA
TCTTGGCACCCGGAGGCAGCGGAGGCAGGCGCAGCATCCTCGCTGGGAACTGGAGCTGGAGTGAGCGCACCGCGCGGGAGGAGCCGCCGC
AGCCTCGCAGAACCCGAGTGGAGGAGGTGACAGCTCCATTGCCGGGTTTTTATTTTTTTTCTCTCCGCCTCCCCGTCTCCTCCTCAGGCT
CGGACCATGGTGCAGTCCCACTGGCTCCCCTGCCCCCCTCTCCTGTGAGACTGGCTGCGGGGAGGGATCATGGATACTTGTCTGCCGGCT
TCTGGTTCCCACGCAAGTAAGCCTGCTGTCAATGGAGGAGGACATTGATACCCGCAAAATCAACAACAGTTTCCTGCGCGACCACAGCTA
TGCGACCGAAGCTGTGGAACAACTATTTTCATCTGGCAGTGGCTTTTATCACCCAGGATTCTCTGCAGCTGGAGCAGTTCTCACACGCCA
AATACAACAAAATCCTGAATAAGTATGGGGACATGAGACGGCTAATTGGCTTCTCCATCCGTGATATGTGGTACAAGCTTGGTCAGAACA
AAATCTGCTTCATCCCAGGCATGGTAGGACCTATATTAGAGATGACACTTATCCCTGAGGCTGAGCTCCGGAAAGCCACCATACCAATCT
TCTTCGACATGATGCTGTGTGAATATCAAAGAAGTGGGGATTTCAAAAAGTTTGAAAACGAAATCATCCTGAAGCTGGACCACGAGGTAG
AAGGGGGCCGAGGCGACGAGCAGTACATGCAGCTCCTGGAGTCAATCCTGATGGAATGTGCTGCAGAGCACCCAACCATTGCCAAGTCGG
TGGAGAACTTCGTGAACCTGGTCAAAGGCCTCCTGGAGAAGCTGCTGGATTACCGGGGTGTGATGACAGATGAGAGCAAAGACAACCGCA
TGAGCTGCACCGTGAACCTGCTGAATTTCTACAAAGATAACAACAGGGAGGAGATGTACATAAGGTACCTGTACAAACTCCGCGATCTTC
ACCTGGACTGTGACAATTACACAGAGGCTGCCTACACGCTCCTTCTCCACACCTGGCTTCTCAAGTGGTCGGATGAGCAGTGTGCATCAC
AGGTCATGCAGACAGGCCAGCAGCACCCCCAGACACACCGGCAGCTGAAGGAGACGCTCTACGAGACCATCATAGGCTACTTTGACAAAG
GAAAGATGTGGGAAGAGGCCATAAGTCTGTGCAAGGAGCTGGCGGAACAGTACGAGATGGAGATCTTTGACTATGAGCTGCTCAGCCAGA
ACCTGATCCAGCAGGCAAAATTCTATGAAAGCATCATGAAAATCCTCAGGCCCAAACCAGACTACTTTGCTGTTGGATACTACGGCCAGG
GATTCCCCTCCTTCCTGCGGAACAAAGTGTTCATCTACCGCGGGAAGGAATATGAGCGAAGAGAAGATTTCCAGATGCAGCTGATGACCC
AGTTCCCCAATGCAGAGAAGATGAACACCACCTCTGCCCCGGGAGATGATGTGAAGAATGCCCCAGGCCAGTATATCCAGTGCTTCACTG
TCCAGCCTGTCTTGGATGAACATCCCAGGTTCAAGAATAAGCCAGTGCCTGACCAGATTATAAACTTCTACAAATCCAACTACGTGCAAA
GGTTCCACTACTCCCGGCCCGTGCGCAGGGGGACCGTAGACCCAGAGAATGAGTTTGCTTCCATGTGGATTGAGAGAACCTCCTTCGTGA
CTGCATACAAGCTGCCGGGGATCCTGCGCTGGTTTGAGGTGGTGCACATGTCGCAGACCACAATTAGTCCTCTGGAGAATGCCATAGAAA
CCATGTCCACGGCCAATGAGAAGATCCTGATGATGATAAACCAGTACCAGAGTGATGAGACCCTCCCCATCAACCCACTCTCCATGCTCC
TGAACGGGATTGTGGACCCTGCTGTCATGGGAGGCTTCGCCAAGTATGAGAAGGCCTTCTTCACTGAAGAGTATGTCAGGGACCACCCTG
AGGACCAGGACAAGCTGACCCACCTCAAGGACCTGATTGCATGGCAGATCCCCTTCTTGGGAGCTGGGATTAAGATCCATGAGAAAAGGG
TGTCAGATAACTTGCGACCCTTCCATGACCGGATGGAGGAATGTTTCAAGAACCTGAAAATGAAGGTGGAGAAGGAGTACGGTGTCCGAG
AGATGCCTGACTTTGACGACAGGAGAGTGGGCCGTCCCAGGTCTATGCTGCGCTCATACAGACAGATGTCCATCATCTCTCTGGCTTCCA
TGAATTCTGACTGCAGCACCCCCAGCAAGCCTACCTCAGAGAGCTTTGACCTGGAATTAGCATCACCCAAGACGCCGAGAGTGGAGCAGG
AGGAACCGATCTCCCCGGGGAGCACCCTGCCTGAGGTCAAGCTGCGGAGGTCCAAGAAGAGGACAAAGAGAAGCAGCGTAGTTTTTGCGG
ATGAGAAAGCAGCTGCAGAGTCGGACCTGAAGCGGCTTTCCAGGAAGCATGAGTTCATGAGTGACACCAACCTCTCGGAGCATGCGGCCA
TCCCCCTCAAGGCGTCTGTCCTCTCTCAAATGAGCTTTGCCAGCCAGTCCATGCCTACCATCCCAGCCCTGGCGCTCTCAGTGGCAGGCA
TCCCTGGGTTGGATGAGGCCAACACATCTCCCCGCCTCAGCCAGACCTTCCTCCAACTCTCAGATGGTGACAAGAAGACACTCACACGGA
AGAAGGTCAATCAGTTCTTCAAGACAATGCTGGCCAGCAAATCGGCTGAAGAAGGCAAACAGATCCCAGACTCGCTGTCCACGGACCTGT
GAGCTGCTGCTGACTAGGGCTGCATGGGAGAGCCAGGGAGGGGAGTTTCTGGAAGAGGAAAGCCATGCGTGGAACATCGAAGCCTCAGAG
AGTGGGAGACTGTCCCCATCAGTTGTCCTTACTTAGAGGAGACAGAGAGGCCAATCAGGTCCCAGAGCTTGAATGCTAACAAGCCCAGCA
TCCCCTGGGGCTGTGATCATGGTGGATGAGGAAGCCTCAACGTAGATTCCTGAACTCAAGGTACCAGCAAGAATGCCTTCTCCCAGTGTG
CTCTCCCCAACATCCTAGGCACAGCTTTCATAACCCAGTTTCTTAGGTGTAAGAAACTGTTTTTATCTCATTTATTAAGTCTCAGAACTT
AACAGAAAAGGAAGCCTTTTAAATATTCTTTTTAATTTTATTTTAGATTAACAGTTTTGTACTTTACATTTTTTTATACAACCAACCAGT

>68013_68013_5_PPP2R2B-DOCK2_PPP2R2B_chr5_146257565_ENST00000394413_DOCK2_chr5_169435501_ENST00000520908_length(amino acids)=825AA_BP=19
MIPAKSTTVSCATTAMRPKLWNNYFHLAVAFITQDSLQLEQFSHAKYNKILNKYGDMRRLIGFSIRDMWYKLGQNKICFIPGMVGPILEM
TLIPEAELRKATIPIFFDMMLCEYQRSGDFKKFENEIILKLDHEVEGGRGDEQYMQLLESILMECAAEHPTIAKSVENFVNLVKGLLEKL
LDYRGVMTDESKDNRMSCTVNLLNFYKDNNREEMYIRYLYKLRDLHLDCDNYTEAAYTLLLHTWLLKWSDEQCASQVMQTGQQHPQTHRQ
LKETLYETIIGYFDKGKMWEEAISLCKELAEQYEMEIFDYELLSQNLIQQAKFYESIMKILRPKPDYFAVGYYGQGFPSFLRNKVFIYRG
KEYERREDFQMQLMTQFPNAEKMNTTSAPGDDVKNAPGQYIQCFTVQPVLDEHPRFKNKPVPDQIINFYKSNYVQRFHYSRPVRRGTVDP
ENEFASMWIERTSFVTAYKLPGILRWFEVVHMSQTTISPLENAIETMSTANEKILMMINQYQSDETLPINPLSMLLNGIVDPAVMGGFAK
YEKAFFTEEYVRDHPEDQDKLTHLKDLIAWQIPFLGAGIKIHEKRVSDNLRPFHDRMEECFKNLKMKVEKEYGVREMPDFDDRRVGRPRS
MLRSYRQMSIISLASMNSDCSTPSKPTSESFDLELASPKTPRVEQEEPISPGSTLPEVKLRRSKKRTKRSSVVFADEKAAAESDLKRLSR
KHEFMSDTNLSEHAAIPLKASVLSQMSFASQSMPTIPALALSVAGIPGLDEANTSPRLSQTFLQLSDGDKKTLTRKKVNQFFKTMLASKS

--------------------------------------------------------------
>68013_68013_6_PPP2R2B-DOCK2_PPP2R2B_chr5_146257565_ENST00000394413_DOCK2_chr5_169435501_ENST00000540750_length(transcript)=3581nt_BP=641nt
CCCGCCTGCCGGAGCCGCCCTCCCGTGGGACCAGCACCCTCATTCCGGCCAGGCAAGCCTGAATCCTGTCCCTGCCATCTCGCCACTGCA
GCTCGGGTCCAGAAAGGCACCATTTTGTCGCGGCTGCCCGCTCTCCCAGGGGGAGGAGGGATCTTTTTTGCATTTTGGAGCGGCTGCCAA
GGAGGGGAACCTGTTGGGCATCTCCCCAGACCCGCTTGTGAGCGCCTCCGGGGCGGGCGGGCGGGACCAGACCCCTCGGGGCACGGCGTA
TCTTGGCACCCGGAGGCAGCGGAGGCAGGCGCAGCATCCTCGCTGGGAACTGGAGCTGGAGTGAGCGCACCGCGCGGGAGGAGCCGCCGC
AGCCTCGCAGAACCCGAGTGGAGGAGGTGACAGCTCCATTGCCGGGTTTTTATTTTTTTTCTCTCCGCCTCCCCGTCTCCTCCTCAGGCT
CGGACCATGGTGCAGTCCCACTGGCTCCCCTGCCCCCCTCTCCTGTGAGACTGGCTGCGGGGAGGGATCATGGATACTTGTCTGCCGGCT
TCTGGTTCCCACGCAAGTAAGCCTGCTGTCAATGGAGGAGGACATTGATACCCGCAAAATCAACAACAGTTTCCTGCGCGACCACAGCTA
TGCGACCGAAGCTGTGGAACAACTATTTTCATCTGGCAGTGGCTTTTATCACCCAGGATTCTCTGCAGCTGGAGCAGTTCTCACACGCCA
AATACAACAAAATCCTGAATAAGTATGGGGACATGAGACGGCTAATTGGCTTCTCCATCCGTGATATGTGGTACAAGCTTGGTCAGAACA
AAATCTGCTTCATCCCAGGCATGGTAGGACCTATATTAGAGATGACACTTATCCCTGAGGCTGAGCTCCGGAAAGCCACCATACCAATCT
TCTTCGACATGATGCTGTGTGAATATCAAAGAAGTGGGGATTTCAAAAAGTTTGAAAACGAAATCATCCTGAAGCTGGACCACGAGGTAG
AAGGGGGCCGAGGCGACGAGCAGTACATGCAGCTCCTGGAGTCAATCCTGATGGAATGTGCTGCAGAGCACCCAACCATTGCCAAGTCGG
TGGAGAACTTCGTGAACCTGGTCAAAGGCCTCCTGGAGAAGCTGCTGGATTACCGGGGTGTGATGACAGATGAGAGCAAAGACAACCGCA
TGAGCTGCACCGTGAACCTGCTGAATTTCTACAAAGATAACAACAGGGAGGAGATGTACATAAGGTACCTGTACAAACTCCGCGATCTTC
ACCTGGACTGTGACAATTACACAGAGGCTGCCTACACGCTCCTTCTCCACACCTGGCTTCTCAAGTGGTCGGATGAGCAGTGTGCATCAC
AGGTCATGCAGACAGGCCAGCAGCACCCCCAGACACACCGGCAGCTGAAGGAGACGCTCTACGAGACCATCATAGGCTACTTTGACAAAG
GAAAGATGTGGGAAGAGGCCATAAGTCTGTGCAAGGAGCTGGCGGAACAGTACGAGATGGAGATCTTTGACTATGAGCTGCTCAGCCAGA
ACCTGATCCAGCAGGCAAAATTCTATGAAAGCATCATGAAAATCCTCAGGCCCAAACCAGACTACTTTGCTGTTGGATACTACGGCCAGG
GATTCCCCTCCTTCCTGCGGAACAAAGTGTTCATCTACCGCGGGAAGGAATATGAGCGAAGAGAAGATTTCCAGATGCAGCTGATGACCC
AGTTCCCCAATGCAGAGAAGATGAACACCACCTCTGCCCCGGGAGATGATGTGAAGAATGCCCCAGGCCAGTATATCCAGTGCTTCACTG
TCCAGCCTGTCTTGGATGAACATCCCAGGTTCAAGAATAAGCCAGTGCCTGACCAGATTATAAACTTCTACAAATCCAACTACGTGCAAA
GGTTCCACTACTCCCGGCCCGTGCGCAGGGGGACCGTAGACCCAGAGAATGAGTTTGCTTCCATGTGGATTGAGAGAACCTCCTTCGTGA
CTGCATACAAGCTGCCGGGGATCCTGCGCTGGTTTGAGGTGGTGCACATGTCGCAGACCACAATTAGTCCTCTGGAGAATGCCATAGAAA
CCATGTCCACGGCCAATGAGAAGATCCTGATGATGATAAACCAGTACCAGAGTGATGAGACCCTCCCCATCAACCCACTCTCCATGCTCC
TGAACGGGATTGTGGACCCTGCTGTCATGGGAGGCTTCGCCAAGTATGAGAAGGCCTTCTTCACTGAAGAGTATGTCAGGGACCACCCTG
AGGACCAGGACAAGCTGACCCACCTCAAGGACCTGATTGCATGGCAGATCCCCTTCTTGGGAGCTGGGATTAAGATCCATGAGAAAAGGG
TGTCAGATAACTTGCGACCCTTCCATGACCGGATGGAGGAATGTTTCAAGAACCTGAAAATGAAGGTGGAGAAGGAGTACGGTGTCCGAG
AGATGCCTGACTTTGACGACAGGAGAGTGGGCCGTCCCAGGTCTATGCTGCGCTCATACAGACAGATGTCCATCATCTCTCTGGCTTCCA
TGAATTCTGACTGCAGCACCCCCAGCAAGCCTACCTCAGAGAGCTTTGACCTGGAATTAGCATCACCCAAGACGCCGAGAGTGGAGCAGG
AGGAACCGATCTCCCCGGGGAGCACCCTGCCTGAGGTCAAGCTGCGGAGGTCCAAGAAGAGGACAAAGAGAAGCAGCGTAGTTTTTGCGG
ATGAGAAAGCAGCTGCAGAGTCGGACCTGAAGCGGCTTTCCAGGAAGCATGAGTTCATGAGTGACACCAACCTCTCGGAGCATGCGGCCA
TCCCCCTCAAGGCGTCTGTCCTCTCTCAAATGAGCTTTGCCAGCCAGTCCATGCCTACCATCCCAGCCCTGGCGCTCTCAGTGGCAGGCA
TCCCTGGGTTGGATGAGGCCAACACATCTCCCCGCCTCAGCCAGACCTTCCTCCAACTCTCAGATGGTGACAAGAAGACACTCACACGGA
AGAAGGTCAATCAGTTCTTCAAGACAATGCTGGCCAGCAAATCGGCTGAAGAAGGCAAACAGATCCCAGACTCGCTGTCCACGGACCTGT
GAGCTGCTGCTGACTAGGGCTGCATGGGAGAGCCAGGGAGGGGAGTTTCTGGAAGAGGAAAGCCATGCGTGGAACATCGAAGCCTCAGAG
AGTGGGAGACTGTCCCCATCAGTTGTCCTTACTTAGAGGAGACAGAGAGGCCAATCAGGTCCCAGAGCTTGAATGCTAACAAGCCCAGCA
TCCCCTGGGGCTGTGATCATGGTGGATGAGGAAGCCTCAACGTAGATTCCTGAACTCAAGGTACCAGCAAGAATGCCTTCTCCCAGTGTG
CTCTCCCCAACATCCTAGGCACAGCTTTCATAACCCAGTTTCTTAGGTGTAAGAAACTGTTTTTATCTCATTTATTAAGTCTCAGAACTT
AACAGAAAAGGAAGCCTTTTAAATATTCTTTTTAATTTTATTTTAGATTAACAGTTTTGTACTTTACATTTTTTTATACAACCAACCAGT

>68013_68013_6_PPP2R2B-DOCK2_PPP2R2B_chr5_146257565_ENST00000394413_DOCK2_chr5_169435501_ENST00000540750_length(amino acids)=825AA_BP=19
MIPAKSTTVSCATTAMRPKLWNNYFHLAVAFITQDSLQLEQFSHAKYNKILNKYGDMRRLIGFSIRDMWYKLGQNKICFIPGMVGPILEM
TLIPEAELRKATIPIFFDMMLCEYQRSGDFKKFENEIILKLDHEVEGGRGDEQYMQLLESILMECAAEHPTIAKSVENFVNLVKGLLEKL
LDYRGVMTDESKDNRMSCTVNLLNFYKDNNREEMYIRYLYKLRDLHLDCDNYTEAAYTLLLHTWLLKWSDEQCASQVMQTGQQHPQTHRQ
LKETLYETIIGYFDKGKMWEEAISLCKELAEQYEMEIFDYELLSQNLIQQAKFYESIMKILRPKPDYFAVGYYGQGFPSFLRNKVFIYRG
KEYERREDFQMQLMTQFPNAEKMNTTSAPGDDVKNAPGQYIQCFTVQPVLDEHPRFKNKPVPDQIINFYKSNYVQRFHYSRPVRRGTVDP
ENEFASMWIERTSFVTAYKLPGILRWFEVVHMSQTTISPLENAIETMSTANEKILMMINQYQSDETLPINPLSMLLNGIVDPAVMGGFAK
YEKAFFTEEYVRDHPEDQDKLTHLKDLIAWQIPFLGAGIKIHEKRVSDNLRPFHDRMEECFKNLKMKVEKEYGVREMPDFDDRRVGRPRS
MLRSYRQMSIISLASMNSDCSTPSKPTSESFDLELASPKTPRVEQEEPISPGSTLPEVKLRRSKKRTKRSSVVFADEKAAAESDLKRLSR
KHEFMSDTNLSEHAAIPLKASVLSQMSFASQSMPTIPALALSVAGIPGLDEANTSPRLSQTFLQLSDGDKKTLTRKKVNQFFKTMLASKS

--------------------------------------------------------------
>68013_68013_7_PPP2R2B-DOCK2_PPP2R2B_chr5_146257565_ENST00000453001_DOCK2_chr5_169435501_ENST00000256935_length(transcript)=3333nt_BP=388nt
GCATGCGCCCCACTGCAGCAAAGAGCAGCCGCAGCCTCTGCCTCGGCCACCACTGCTGCTGGGAAAGAGTCGTGGGGCTGCTGACGCGGT
TGGGAGGAGCCTCGCCTTTAATGCACCAGCCGCCTCCAGCCTCCTGCAGCAGCAGCAGCAGCAGCAGCAGCAGCAGCTGCGAGTGCGCGC
GTGTGGGTGTGAGGGCTCGGACCATGGTGCAGTCCCACTGGCTCCCCTGCCCCCCTCTCCTGTGAGACTGGCTGCGGGGAGGGATCATGG
ATACTTGTCTGCCGGCTTCTGGTTCCCACGCAAGTAAGCCTGCTGTCAATGGAGGAGGACATTGATACCCGCAAAATCAACAACAGTTTC
CTGCGCGACCACAGCTATGCGACCGAAGCTGTGGAACAACTATTTTCATCTGGCAGTGGCTTTTATCACCCAGGATTCTCTGCAGCTGGA
GCAGTTCTCACACGCCAAATACAACAAAATCCTGAATAAGTATGGGGACATGAGACGGCTAATTGGCTTCTCCATCCGTGATATGTGGTA
CAAGCTTGGTCAGAACAAAATCTGCTTCATCCCAGGCATGGTAGGACCTATATTAGAGATGACACTTATCCCTGAGGCTGAGCTCCGGAA
AGCCACCATACCAATCTTCTTCGACATGATGCTGTGTGAATATCAAAGAAGTGGGGATTTCAAAAAGTTTGAAAACGAAATCATCCTGAA
GCTGGACCACGAGGTAGAAGGGGGCCGAGGCGACGAGCAGTACATGCAGCTCCTGGAGTCAATCCTGATGGAATGTGCTGCAGAGCACCC
AACCATTGCCAAGTCGGTGGAGAACTTCGTGAACCTGGTCAAAGGCCTCCTGGAGAAGCTGCTGGATTACCGGGGTGTGATGACAGATGA
GAGCAAAGACAACCGCATGAGCTGCACCGTGAACCTGCTGAATTTCTACAAAGATAACAACAGGGAGGAGATGTACATAAGGTACCTGTA
CAAACTCCGCGATCTTCACCTGGACTGTGACAATTACACAGAGGCTGCCTACACGCTCCTTCTCCACACCTGGCTTCTCAAGTGGTCGGA
TGAGCAGTGTGCATCACAGGTCATGCAGACAGGCCAGCAGCACCCCCAGACACACCGGCAGCTGAAGGAGACGCTCTACGAGACCATCAT
AGGCTACTTTGACAAAGGAAAGATGTGGGAAGAGGCCATAAGTCTGTGCAAGGAGCTGGCGGAACAGTACGAGATGGAGATCTTTGACTA
TGAGCTGCTCAGCCAGAACCTGATCCAGCAGGCAAAATTCTATGAAAGCATCATGAAAATCCTCAGGCCCAAACCAGACTACTTTGCTGT
TGGATACTACGGCCAGGGATTCCCCTCCTTCCTGCGGAACAAAGTGTTCATCTACCGCGGGAAGGAATATGAGCGAAGAGAAGATTTCCA
GATGCAGCTGATGACCCAGTTCCCCAATGCAGAGAAGATGAACACCACCTCTGCCCCGGGAGATGATGTGAAGAATGCCCCAGGCCAGTA
TATCCAGTGCTTCACTGTCCAGCCTGTCTTGGATGAACATCCCAGGTTCAAGAATAAGCCAGTGCCTGACCAGATTATAAACTTCTACAA
ATCCAACTACGTGCAAAGGTTCCACTACTCCCGGCCCGTGCGCAGGGGGACCGTAGACCCAGAGAATGAGTTTGCTTCCATGTGGATTGA
GAGAACCTCCTTCGTGACTGCATACAAGCTGCCGGGGATCCTGCGCTGGTTTGAGGTGGTGCACATGTCGCAGACCACAATTAGTCCTCT
GGAGAATGCCATAGAAACCATGTCCACGGCCAATGAGAAGATCCTGATGATGATAAACCAGTACCAGAGTGATGAGACCCTCCCCATCAA
CCCACTCTCCATGCTCCTGAACGGGATTGTGGACCCTGCTGTCATGGGAGGCTTCGCCAAGTATGAGAAGGCCTTCTTCACTGAAGAGTA
TGTCAGGGACCACCCTGAGGACCAGGACAAGCTGACCCACCTCAAGGACCTGATTGCATGGCAGATCCCCTTCTTGGGAGCTGGGATTAA
GATCCATGAGAAAAGGGTGTCAGATAACTTGCGACCCTTCCATGACCGGATGGAGGAATGTTTCAAGAACCTGAAAATGAAGGTGGAGAA
GGAGTACGGTGTCCGAGAGATGCCTGACTTTGACGACAGGAGAGTGGGCCGTCCCAGGTCTATGCTGCGCTCATACAGACAGATGTCCAT
CATCTCTCTGGCTTCCATGAATTCTGACTGCAGCACCCCCAGCAAGCCTACCTCAGAGAGCTTTGACCTGGAATTAGCATCACCCAAGAC
GCCGAGAGTGGAGCAGGAGGAACCGATCTCCCCGGGGAGCACCCTGCCTGAGGTCAAGCTGCGGAGGTCCAAGAAGAGGACAAAGAGAAG
CAGCGTAGTTTTTGCGGATGAGAAAGCAGCTGCAGAGTCGGACCTGAAGCGGCTTTCCAGGAAGCATGAGTTCATGAGTGACACCAACCT
CTCGGAGCATGCGGCCATCCCCCTCAAGGCGTCTGTCCTCTCTCAAATGAGCTTTGCCAGCCAGTCCATGCCTACCATCCCAGCCCTGGC
GCTCTCAGTGGCAGGCATCCCTGGGTTGGATGAGGCCAACACATCTCCCCGCCTCAGCCAGACCTTCCTCCAACTCTCAGATGGTGACAA
GAAGACACTCACACGGAAGAAGGTCAATCAGTTCTTCAAGACAATGCTGGCCAGCAAATCGGCTGAAGAAGGCAAACAGATCCCAGACTC
GCTGTCCACGGACCTGTGAGCTGCTGCTGACTAGGGCTGCATGGGAGAGCCAGGGAGGGGAGTTTCTGGAAGAGGAAAGCCATGCGTGGA
ACATCGAAGCCTCAGAGAGTGGGAGACTGTCCCCATCAGTTGTCCTTACTTAGAGGAGACAGAGAGGCCAATCAGGTCCCAGAGCTTGAA
TGCTAACAAGCCCAGCATCCCCTGGGGCTGTGATCATGGTGGATGAGGAAGCCTCAACGTAGATTCCTGAACTCAAGGTACCAGCAAGAA
TGCCTTCTCCCAGTGTGCTCTCCCCAACATCCTAGGCACAGCTTTCATAACCCAGTTTCTTAGGTGTAAGAAACTGTTTTTATCTCATTT
ATTAAGTCTCAGAACTTAACAGAAAAGGAAGCCTTTTAAATATTCTTTTTAATTTTATTTTAGATTAACAGTTTTGTACTTTACATTTTT
TTATACAACCAACCAGTTTCTTTTCTAGCCAATCATCTCTGAAGAGTTGCTGTTTCTTACTGACAATAAAAAATGTTCTCTTGGTTCGAA

>68013_68013_7_PPP2R2B-DOCK2_PPP2R2B_chr5_146257565_ENST00000453001_DOCK2_chr5_169435501_ENST00000256935_length(amino acids)=825AA_BP=19
MIPAKSTTVSCATTAMRPKLWNNYFHLAVAFITQDSLQLEQFSHAKYNKILNKYGDMRRLIGFSIRDMWYKLGQNKICFIPGMVGPILEM
TLIPEAELRKATIPIFFDMMLCEYQRSGDFKKFENEIILKLDHEVEGGRGDEQYMQLLESILMECAAEHPTIAKSVENFVNLVKGLLEKL
LDYRGVMTDESKDNRMSCTVNLLNFYKDNNREEMYIRYLYKLRDLHLDCDNYTEAAYTLLLHTWLLKWSDEQCASQVMQTGQQHPQTHRQ
LKETLYETIIGYFDKGKMWEEAISLCKELAEQYEMEIFDYELLSQNLIQQAKFYESIMKILRPKPDYFAVGYYGQGFPSFLRNKVFIYRG
KEYERREDFQMQLMTQFPNAEKMNTTSAPGDDVKNAPGQYIQCFTVQPVLDEHPRFKNKPVPDQIINFYKSNYVQRFHYSRPVRRGTVDP
ENEFASMWIERTSFVTAYKLPGILRWFEVVHMSQTTISPLENAIETMSTANEKILMMINQYQSDETLPINPLSMLLNGIVDPAVMGGFAK
YEKAFFTEEYVRDHPEDQDKLTHLKDLIAWQIPFLGAGIKIHEKRVSDNLRPFHDRMEECFKNLKMKVEKEYGVREMPDFDDRRVGRPRS
MLRSYRQMSIISLASMNSDCSTPSKPTSESFDLELASPKTPRVEQEEPISPGSTLPEVKLRRSKKRTKRSSVVFADEKAAAESDLKRLSR
KHEFMSDTNLSEHAAIPLKASVLSQMSFASQSMPTIPALALSVAGIPGLDEANTSPRLSQTFLQLSDGDKKTLTRKKVNQFFKTMLASKS

--------------------------------------------------------------
>68013_68013_8_PPP2R2B-DOCK2_PPP2R2B_chr5_146257565_ENST00000453001_DOCK2_chr5_169435501_ENST00000520908_length(transcript)=3330nt_BP=388nt
GCATGCGCCCCACTGCAGCAAAGAGCAGCCGCAGCCTCTGCCTCGGCCACCACTGCTGCTGGGAAAGAGTCGTGGGGCTGCTGACGCGGT
TGGGAGGAGCCTCGCCTTTAATGCACCAGCCGCCTCCAGCCTCCTGCAGCAGCAGCAGCAGCAGCAGCAGCAGCAGCTGCGAGTGCGCGC
GTGTGGGTGTGAGGGCTCGGACCATGGTGCAGTCCCACTGGCTCCCCTGCCCCCCTCTCCTGTGAGACTGGCTGCGGGGAGGGATCATGG
ATACTTGTCTGCCGGCTTCTGGTTCCCACGCAAGTAAGCCTGCTGTCAATGGAGGAGGACATTGATACCCGCAAAATCAACAACAGTTTC
CTGCGCGACCACAGCTATGCGACCGAAGCTGTGGAACAACTATTTTCATCTGGCAGTGGCTTTTATCACCCAGGATTCTCTGCAGCTGGA
GCAGTTCTCACACGCCAAATACAACAAAATCCTGAATAAGTATGGGGACATGAGACGGCTAATTGGCTTCTCCATCCGTGATATGTGGTA
CAAGCTTGGTCAGAACAAAATCTGCTTCATCCCAGGCATGGTAGGACCTATATTAGAGATGACACTTATCCCTGAGGCTGAGCTCCGGAA
AGCCACCATACCAATCTTCTTCGACATGATGCTGTGTGAATATCAAAGAAGTGGGGATTTCAAAAAGTTTGAAAACGAAATCATCCTGAA
GCTGGACCACGAGGTAGAAGGGGGCCGAGGCGACGAGCAGTACATGCAGCTCCTGGAGTCAATCCTGATGGAATGTGCTGCAGAGCACCC
AACCATTGCCAAGTCGGTGGAGAACTTCGTGAACCTGGTCAAAGGCCTCCTGGAGAAGCTGCTGGATTACCGGGGTGTGATGACAGATGA
GAGCAAAGACAACCGCATGAGCTGCACCGTGAACCTGCTGAATTTCTACAAAGATAACAACAGGGAGGAGATGTACATAAGGTACCTGTA
CAAACTCCGCGATCTTCACCTGGACTGTGACAATTACACAGAGGCTGCCTACACGCTCCTTCTCCACACCTGGCTTCTCAAGTGGTCGGA
TGAGCAGTGTGCATCACAGGTCATGCAGACAGGCCAGCAGCACCCCCAGACACACCGGCAGCTGAAGGAGACGCTCTACGAGACCATCAT
AGGCTACTTTGACAAAGGAAAGATGTGGGAAGAGGCCATAAGTCTGTGCAAGGAGCTGGCGGAACAGTACGAGATGGAGATCTTTGACTA
TGAGCTGCTCAGCCAGAACCTGATCCAGCAGGCAAAATTCTATGAAAGCATCATGAAAATCCTCAGGCCCAAACCAGACTACTTTGCTGT
TGGATACTACGGCCAGGGATTCCCCTCCTTCCTGCGGAACAAAGTGTTCATCTACCGCGGGAAGGAATATGAGCGAAGAGAAGATTTCCA
GATGCAGCTGATGACCCAGTTCCCCAATGCAGAGAAGATGAACACCACCTCTGCCCCGGGAGATGATGTGAAGAATGCCCCAGGCCAGTA
TATCCAGTGCTTCACTGTCCAGCCTGTCTTGGATGAACATCCCAGGTTCAAGAATAAGCCAGTGCCTGACCAGATTATAAACTTCTACAA
ATCCAACTACGTGCAAAGGTTCCACTACTCCCGGCCCGTGCGCAGGGGGACCGTAGACCCAGAGAATGAGTTTGCTTCCATGTGGATTGA
GAGAACCTCCTTCGTGACTGCATACAAGCTGCCGGGGATCCTGCGCTGGTTTGAGGTGGTGCACATGTCGCAGACCACAATTAGTCCTCT
GGAGAATGCCATAGAAACCATGTCCACGGCCAATGAGAAGATCCTGATGATGATAAACCAGTACCAGAGTGATGAGACCCTCCCCATCAA
CCCACTCTCCATGCTCCTGAACGGGATTGTGGACCCTGCTGTCATGGGAGGCTTCGCCAAGTATGAGAAGGCCTTCTTCACTGAAGAGTA
TGTCAGGGACCACCCTGAGGACCAGGACAAGCTGACCCACCTCAAGGACCTGATTGCATGGCAGATCCCCTTCTTGGGAGCTGGGATTAA
GATCCATGAGAAAAGGGTGTCAGATAACTTGCGACCCTTCCATGACCGGATGGAGGAATGTTTCAAGAACCTGAAAATGAAGGTGGAGAA
GGAGTACGGTGTCCGAGAGATGCCTGACTTTGACGACAGGAGAGTGGGCCGTCCCAGGTCTATGCTGCGCTCATACAGACAGATGTCCAT
CATCTCTCTGGCTTCCATGAATTCTGACTGCAGCACCCCCAGCAAGCCTACCTCAGAGAGCTTTGACCTGGAATTAGCATCACCCAAGAC
GCCGAGAGTGGAGCAGGAGGAACCGATCTCCCCGGGGAGCACCCTGCCTGAGGTCAAGCTGCGGAGGTCCAAGAAGAGGACAAAGAGAAG
CAGCGTAGTTTTTGCGGATGAGAAAGCAGCTGCAGAGTCGGACCTGAAGCGGCTTTCCAGGAAGCATGAGTTCATGAGTGACACCAACCT
CTCGGAGCATGCGGCCATCCCCCTCAAGGCGTCTGTCCTCTCTCAAATGAGCTTTGCCAGCCAGTCCATGCCTACCATCCCAGCCCTGGC
GCTCTCAGTGGCAGGCATCCCTGGGTTGGATGAGGCCAACACATCTCCCCGCCTCAGCCAGACCTTCCTCCAACTCTCAGATGGTGACAA
GAAGACACTCACACGGAAGAAGGTCAATCAGTTCTTCAAGACAATGCTGGCCAGCAAATCGGCTGAAGAAGGCAAACAGATCCCAGACTC
GCTGTCCACGGACCTGTGAGCTGCTGCTGACTAGGGCTGCATGGGAGAGCCAGGGAGGGGAGTTTCTGGAAGAGGAAAGCCATGCGTGGA
ACATCGAAGCCTCAGAGAGTGGGAGACTGTCCCCATCAGTTGTCCTTACTTAGAGGAGACAGAGAGGCCAATCAGGTCCCAGAGCTTGAA
TGCTAACAAGCCCAGCATCCCCTGGGGCTGTGATCATGGTGGATGAGGAAGCCTCAACGTAGATTCCTGAACTCAAGGTACCAGCAAGAA
TGCCTTCTCCCAGTGTGCTCTCCCCAACATCCTAGGCACAGCTTTCATAACCCAGTTTCTTAGGTGTAAGAAACTGTTTTTATCTCATTT
ATTAAGTCTCAGAACTTAACAGAAAAGGAAGCCTTTTAAATATTCTTTTTAATTTTATTTTAGATTAACAGTTTTGTACTTTACATTTTT
TTATACAACCAACCAGTTTCTTTTCTAGCCAATCATCTCTGAAGAGTTGCTGTTTCTTACTGACAATAAAAAATGTTCTCTTGGTTCGAA

>68013_68013_8_PPP2R2B-DOCK2_PPP2R2B_chr5_146257565_ENST00000453001_DOCK2_chr5_169435501_ENST00000520908_length(amino acids)=825AA_BP=19
MIPAKSTTVSCATTAMRPKLWNNYFHLAVAFITQDSLQLEQFSHAKYNKILNKYGDMRRLIGFSIRDMWYKLGQNKICFIPGMVGPILEM
TLIPEAELRKATIPIFFDMMLCEYQRSGDFKKFENEIILKLDHEVEGGRGDEQYMQLLESILMECAAEHPTIAKSVENFVNLVKGLLEKL
LDYRGVMTDESKDNRMSCTVNLLNFYKDNNREEMYIRYLYKLRDLHLDCDNYTEAAYTLLLHTWLLKWSDEQCASQVMQTGQQHPQTHRQ
LKETLYETIIGYFDKGKMWEEAISLCKELAEQYEMEIFDYELLSQNLIQQAKFYESIMKILRPKPDYFAVGYYGQGFPSFLRNKVFIYRG
KEYERREDFQMQLMTQFPNAEKMNTTSAPGDDVKNAPGQYIQCFTVQPVLDEHPRFKNKPVPDQIINFYKSNYVQRFHYSRPVRRGTVDP
ENEFASMWIERTSFVTAYKLPGILRWFEVVHMSQTTISPLENAIETMSTANEKILMMINQYQSDETLPINPLSMLLNGIVDPAVMGGFAK
YEKAFFTEEYVRDHPEDQDKLTHLKDLIAWQIPFLGAGIKIHEKRVSDNLRPFHDRMEECFKNLKMKVEKEYGVREMPDFDDRRVGRPRS
MLRSYRQMSIISLASMNSDCSTPSKPTSESFDLELASPKTPRVEQEEPISPGSTLPEVKLRRSKKRTKRSSVVFADEKAAAESDLKRLSR
KHEFMSDTNLSEHAAIPLKASVLSQMSFASQSMPTIPALALSVAGIPGLDEANTSPRLSQTFLQLSDGDKKTLTRKKVNQFFKTMLASKS

--------------------------------------------------------------
>68013_68013_9_PPP2R2B-DOCK2_PPP2R2B_chr5_146257565_ENST00000453001_DOCK2_chr5_169435501_ENST00000540750_length(transcript)=3328nt_BP=388nt
GCATGCGCCCCACTGCAGCAAAGAGCAGCCGCAGCCTCTGCCTCGGCCACCACTGCTGCTGGGAAAGAGTCGTGGGGCTGCTGACGCGGT
TGGGAGGAGCCTCGCCTTTAATGCACCAGCCGCCTCCAGCCTCCTGCAGCAGCAGCAGCAGCAGCAGCAGCAGCAGCTGCGAGTGCGCGC
GTGTGGGTGTGAGGGCTCGGACCATGGTGCAGTCCCACTGGCTCCCCTGCCCCCCTCTCCTGTGAGACTGGCTGCGGGGAGGGATCATGG
ATACTTGTCTGCCGGCTTCTGGTTCCCACGCAAGTAAGCCTGCTGTCAATGGAGGAGGACATTGATACCCGCAAAATCAACAACAGTTTC
CTGCGCGACCACAGCTATGCGACCGAAGCTGTGGAACAACTATTTTCATCTGGCAGTGGCTTTTATCACCCAGGATTCTCTGCAGCTGGA
GCAGTTCTCACACGCCAAATACAACAAAATCCTGAATAAGTATGGGGACATGAGACGGCTAATTGGCTTCTCCATCCGTGATATGTGGTA
CAAGCTTGGTCAGAACAAAATCTGCTTCATCCCAGGCATGGTAGGACCTATATTAGAGATGACACTTATCCCTGAGGCTGAGCTCCGGAA
AGCCACCATACCAATCTTCTTCGACATGATGCTGTGTGAATATCAAAGAAGTGGGGATTTCAAAAAGTTTGAAAACGAAATCATCCTGAA
GCTGGACCACGAGGTAGAAGGGGGCCGAGGCGACGAGCAGTACATGCAGCTCCTGGAGTCAATCCTGATGGAATGTGCTGCAGAGCACCC
AACCATTGCCAAGTCGGTGGAGAACTTCGTGAACCTGGTCAAAGGCCTCCTGGAGAAGCTGCTGGATTACCGGGGTGTGATGACAGATGA
GAGCAAAGACAACCGCATGAGCTGCACCGTGAACCTGCTGAATTTCTACAAAGATAACAACAGGGAGGAGATGTACATAAGGTACCTGTA
CAAACTCCGCGATCTTCACCTGGACTGTGACAATTACACAGAGGCTGCCTACACGCTCCTTCTCCACACCTGGCTTCTCAAGTGGTCGGA
TGAGCAGTGTGCATCACAGGTCATGCAGACAGGCCAGCAGCACCCCCAGACACACCGGCAGCTGAAGGAGACGCTCTACGAGACCATCAT
AGGCTACTTTGACAAAGGAAAGATGTGGGAAGAGGCCATAAGTCTGTGCAAGGAGCTGGCGGAACAGTACGAGATGGAGATCTTTGACTA
TGAGCTGCTCAGCCAGAACCTGATCCAGCAGGCAAAATTCTATGAAAGCATCATGAAAATCCTCAGGCCCAAACCAGACTACTTTGCTGT
TGGATACTACGGCCAGGGATTCCCCTCCTTCCTGCGGAACAAAGTGTTCATCTACCGCGGGAAGGAATATGAGCGAAGAGAAGATTTCCA
GATGCAGCTGATGACCCAGTTCCCCAATGCAGAGAAGATGAACACCACCTCTGCCCCGGGAGATGATGTGAAGAATGCCCCAGGCCAGTA
TATCCAGTGCTTCACTGTCCAGCCTGTCTTGGATGAACATCCCAGGTTCAAGAATAAGCCAGTGCCTGACCAGATTATAAACTTCTACAA
ATCCAACTACGTGCAAAGGTTCCACTACTCCCGGCCCGTGCGCAGGGGGACCGTAGACCCAGAGAATGAGTTTGCTTCCATGTGGATTGA
GAGAACCTCCTTCGTGACTGCATACAAGCTGCCGGGGATCCTGCGCTGGTTTGAGGTGGTGCACATGTCGCAGACCACAATTAGTCCTCT
GGAGAATGCCATAGAAACCATGTCCACGGCCAATGAGAAGATCCTGATGATGATAAACCAGTACCAGAGTGATGAGACCCTCCCCATCAA
CCCACTCTCCATGCTCCTGAACGGGATTGTGGACCCTGCTGTCATGGGAGGCTTCGCCAAGTATGAGAAGGCCTTCTTCACTGAAGAGTA
TGTCAGGGACCACCCTGAGGACCAGGACAAGCTGACCCACCTCAAGGACCTGATTGCATGGCAGATCCCCTTCTTGGGAGCTGGGATTAA
GATCCATGAGAAAAGGGTGTCAGATAACTTGCGACCCTTCCATGACCGGATGGAGGAATGTTTCAAGAACCTGAAAATGAAGGTGGAGAA
GGAGTACGGTGTCCGAGAGATGCCTGACTTTGACGACAGGAGAGTGGGCCGTCCCAGGTCTATGCTGCGCTCATACAGACAGATGTCCAT
CATCTCTCTGGCTTCCATGAATTCTGACTGCAGCACCCCCAGCAAGCCTACCTCAGAGAGCTTTGACCTGGAATTAGCATCACCCAAGAC
GCCGAGAGTGGAGCAGGAGGAACCGATCTCCCCGGGGAGCACCCTGCCTGAGGTCAAGCTGCGGAGGTCCAAGAAGAGGACAAAGAGAAG
CAGCGTAGTTTTTGCGGATGAGAAAGCAGCTGCAGAGTCGGACCTGAAGCGGCTTTCCAGGAAGCATGAGTTCATGAGTGACACCAACCT
CTCGGAGCATGCGGCCATCCCCCTCAAGGCGTCTGTCCTCTCTCAAATGAGCTTTGCCAGCCAGTCCATGCCTACCATCCCAGCCCTGGC
GCTCTCAGTGGCAGGCATCCCTGGGTTGGATGAGGCCAACACATCTCCCCGCCTCAGCCAGACCTTCCTCCAACTCTCAGATGGTGACAA
GAAGACACTCACACGGAAGAAGGTCAATCAGTTCTTCAAGACAATGCTGGCCAGCAAATCGGCTGAAGAAGGCAAACAGATCCCAGACTC
GCTGTCCACGGACCTGTGAGCTGCTGCTGACTAGGGCTGCATGGGAGAGCCAGGGAGGGGAGTTTCTGGAAGAGGAAAGCCATGCGTGGA
ACATCGAAGCCTCAGAGAGTGGGAGACTGTCCCCATCAGTTGTCCTTACTTAGAGGAGACAGAGAGGCCAATCAGGTCCCAGAGCTTGAA
TGCTAACAAGCCCAGCATCCCCTGGGGCTGTGATCATGGTGGATGAGGAAGCCTCAACGTAGATTCCTGAACTCAAGGTACCAGCAAGAA
TGCCTTCTCCCAGTGTGCTCTCCCCAACATCCTAGGCACAGCTTTCATAACCCAGTTTCTTAGGTGTAAGAAACTGTTTTTATCTCATTT
ATTAAGTCTCAGAACTTAACAGAAAAGGAAGCCTTTTAAATATTCTTTTTAATTTTATTTTAGATTAACAGTTTTGTACTTTACATTTTT

>68013_68013_9_PPP2R2B-DOCK2_PPP2R2B_chr5_146257565_ENST00000453001_DOCK2_chr5_169435501_ENST00000540750_length(amino acids)=825AA_BP=19
MIPAKSTTVSCATTAMRPKLWNNYFHLAVAFITQDSLQLEQFSHAKYNKILNKYGDMRRLIGFSIRDMWYKLGQNKICFIPGMVGPILEM
TLIPEAELRKATIPIFFDMMLCEYQRSGDFKKFENEIILKLDHEVEGGRGDEQYMQLLESILMECAAEHPTIAKSVENFVNLVKGLLEKL
LDYRGVMTDESKDNRMSCTVNLLNFYKDNNREEMYIRYLYKLRDLHLDCDNYTEAAYTLLLHTWLLKWSDEQCASQVMQTGQQHPQTHRQ
LKETLYETIIGYFDKGKMWEEAISLCKELAEQYEMEIFDYELLSQNLIQQAKFYESIMKILRPKPDYFAVGYYGQGFPSFLRNKVFIYRG
KEYERREDFQMQLMTQFPNAEKMNTTSAPGDDVKNAPGQYIQCFTVQPVLDEHPRFKNKPVPDQIINFYKSNYVQRFHYSRPVRRGTVDP
ENEFASMWIERTSFVTAYKLPGILRWFEVVHMSQTTISPLENAIETMSTANEKILMMINQYQSDETLPINPLSMLLNGIVDPAVMGGFAK
YEKAFFTEEYVRDHPEDQDKLTHLKDLIAWQIPFLGAGIKIHEKRVSDNLRPFHDRMEECFKNLKMKVEKEYGVREMPDFDDRRVGRPRS
MLRSYRQMSIISLASMNSDCSTPSKPTSESFDLELASPKTPRVEQEEPISPGSTLPEVKLRRSKKRTKRSSVVFADEKAAAESDLKRLSR
KHEFMSDTNLSEHAAIPLKASVLSQMSFASQSMPTIPALALSVAGIPGLDEANTSPRLSQTFLQLSDGDKKTLTRKKVNQFFKTMLASKS

--------------------------------------------------------------

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Fusion Gene PPI Analysis for PPP2R2B-DOCK2


check button Go to ChiPPI (Chimeric Protein-Protein interactions) to see the chimeric PPI interaction in

ChiPPI page.


check button Protein-protein interactors with each fusion partner protein in wild-type (BIOGRID-3.4.160)
HgeneHgene's interactorsTgeneTgene's interactors


check button - Retained PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenStill interaction with


check button - Lost PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with
TgeneDOCK2chr5:146257565chr5:169435501ENST000002569352952939_14761024.01831.0CRKL


check button - Retained PPIs, but lost function due to frame-shift fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


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Related Drugs for PPP2R2B-DOCK2


check button Drugs targeting genes involved in this fusion gene.
(DrugBank Version 5.1.8 2021-05-08)
PartnerGeneUniProtAccDrugBank IDDrug nameDrug activityDrug typeDrug status

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Related Diseases for PPP2R2B-DOCK2


check button Diseases associated with fusion partners.
(DisGeNet 4.0)
PartnerGeneDisease IDDisease name# pubmedsSource