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Center for Computational Systems Medicine
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Fusion Gene Summary

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Fusion Gene ORF analysis

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Fusion Genomic Features

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Fusion Protein Features

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Fusion Gene Sequence

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Fusion Gene PPI analysis

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Related Drugs

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Related Diseases

Fusion gene:PPP2R5C-SCN1B (FusionGDB2 ID:68084)

Fusion Gene Summary for PPP2R5C-SCN1B

check button Fusion gene summary
Fusion gene informationFusion gene name: PPP2R5C-SCN1B
Fusion gene ID: 68084
HgeneTgene
Gene symbol

PPP2R5C

SCN1B

Gene ID

5527

6324

Gene nameprotein phosphatase 2 regulatory subunit B'gammasodium voltage-gated channel beta subunit 1
SynonymsB56G|B56gamma|PR61GATFB13|BRGDA5|EIEE52|GEFSP1
Cytomap

14q32.31

19q13.11

Type of geneprotein-codingprotein-coding
Descriptionserine/threonine-protein phosphatase 2A 56 kDa regulatory subunit gamma isoformB' alpha regulatory subunitPP2A B subunit isoform B'-gammaPP2A B subunit isoform B56-gammaPP2A B subunit isoform PR61-gammaPP2A B subunit isoform R5-gammaprotein phosphatsodium channel subunit beta-1sodium channel, voltage gated, type I beta subunitsodium channel, voltage-gated, type I, beta
Modification date2020031320200313
UniProtAcc..
Ensembl transtripts involved in fusion geneENST00000334743, ENST00000350249, 
ENST00000445439, ENST00000556946, 
ENST00000557095, ENST00000557714, 
ENST00000328724, ENST00000422945, 
ENST00000554442, ENST00000556068, 
ENST00000556260, 		ENST00000596348, 
ENST00000262631, ENST00000415950, 
ENST00000595652, 
Fusion gene scores* DoF score18 X 11 X 8=15844 X 2 X 4=32
# samples 195
** MAII scorelog2(19/1584*10)=-3.05950101174866
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0		log2(5/32*10)=0.643856189774725
effective Gene in Pan-Cancer Fusion Genes (eGinPCFGs).
DoF>8 and MAII>0
Context

PubMed: PPP2R5C [Title/Abstract] AND SCN1B [Title/Abstract] AND fusion [Title/Abstract]

Most frequent breakpointPPP2R5C(102276373)-SCN1B(35523432), # samples:2
Anticipated loss of major functional domain due to fusion event.
* DoF score (Degree of Frequency) = # partners X # break points X # cancer types
** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10)

check button Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez
PartnerGeneGO IDGO termPubMed ID
HgenePPP2R5C

GO:0008285

negative regulation of cell proliferation

17245430

TgeneSCN1B

GO:0010765

positive regulation of sodium ion transport

19808477

TgeneSCN1B

GO:0035725

sodium ion transmembrane transport

18464934|19808477|21051419

TgeneSCN1B

GO:0051899

membrane depolarization

21051419

TgeneSCN1B

GO:2000649

regulation of sodium ion transmembrane transporter activity

19808477


check buttonFusion gene breakpoints across PPP2R5C (5'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.
all structure

check buttonFusion gene breakpoints across SCN1B (3'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.
all structure

check button Fusion gene information from two resources (ChiTars 5.0 and ChimerDB 4.0)
* All genome coordinats were lifted-over on hg19.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
SourceDiseaseSampleHgeneHchrHbpHstrandTgeneTchrTbpTstrand
ChimerDB4BRCATCGA-B6-A0RT-01APPP2R5Cchr14

102276373

-SCN1Bchr19

35523432

+
ChimerDB4BRCATCGA-B6-A0RT-01APPP2R5Cchr14

102276373

+SCN1Bchr19

35523432

+


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Fusion Gene ORF analysis for PPP2R5C-SCN1B

check button Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
ORFHenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrand
5CDS-3UTRENST00000334743ENST00000596348PPP2R5Cchr14

102276373

+SCN1Bchr19

35523432

+
5CDS-3UTRENST00000350249ENST00000596348PPP2R5Cchr14

102276373

+SCN1Bchr19

35523432

+
5CDS-3UTRENST00000445439ENST00000596348PPP2R5Cchr14

102276373

+SCN1Bchr19

35523432

+
5CDS-3UTRENST00000556946ENST00000596348PPP2R5Cchr14

102276373

+SCN1Bchr19

35523432

+
5CDS-3UTRENST00000557095ENST00000596348PPP2R5Cchr14

102276373

+SCN1Bchr19

35523432

+
5CDS-3UTRENST00000557714ENST00000596348PPP2R5Cchr14

102276373

+SCN1Bchr19

35523432

+
In-frameENST00000334743ENST00000262631PPP2R5Cchr14

102276373

+SCN1Bchr19

35523432

+
In-frameENST00000334743ENST00000415950PPP2R5Cchr14

102276373

+SCN1Bchr19

35523432

+
In-frameENST00000334743ENST00000595652PPP2R5Cchr14

102276373

+SCN1Bchr19

35523432

+
In-frameENST00000350249ENST00000262631PPP2R5Cchr14

102276373

+SCN1Bchr19

35523432

+
In-frameENST00000350249ENST00000415950PPP2R5Cchr14

102276373

+SCN1Bchr19

35523432

+
In-frameENST00000350249ENST00000595652PPP2R5Cchr14

102276373

+SCN1Bchr19

35523432

+
In-frameENST00000445439ENST00000262631PPP2R5Cchr14

102276373

+SCN1Bchr19

35523432

+
In-frameENST00000445439ENST00000415950PPP2R5Cchr14

102276373

+SCN1Bchr19

35523432

+
In-frameENST00000445439ENST00000595652PPP2R5Cchr14

102276373

+SCN1Bchr19

35523432

+
In-frameENST00000556946ENST00000262631PPP2R5Cchr14

102276373

+SCN1Bchr19

35523432

+
In-frameENST00000556946ENST00000415950PPP2R5Cchr14

102276373

+SCN1Bchr19

35523432

+
In-frameENST00000556946ENST00000595652PPP2R5Cchr14

102276373

+SCN1Bchr19

35523432

+
In-frameENST00000557095ENST00000262631PPP2R5Cchr14

102276373

+SCN1Bchr19

35523432

+
In-frameENST00000557095ENST00000415950PPP2R5Cchr14

102276373

+SCN1Bchr19

35523432

+
In-frameENST00000557095ENST00000595652PPP2R5Cchr14

102276373

+SCN1Bchr19

35523432

+
In-frameENST00000557714ENST00000262631PPP2R5Cchr14

102276373

+SCN1Bchr19

35523432

+
In-frameENST00000557714ENST00000415950PPP2R5Cchr14

102276373

+SCN1Bchr19

35523432

+
In-frameENST00000557714ENST00000595652PPP2R5Cchr14

102276373

+SCN1Bchr19

35523432

+
intron-3CDSENST00000328724ENST00000262631PPP2R5Cchr14

102276373

+SCN1Bchr19

35523432

+
intron-3CDSENST00000328724ENST00000415950PPP2R5Cchr14

102276373

+SCN1Bchr19

35523432

+
intron-3CDSENST00000328724ENST00000595652PPP2R5Cchr14

102276373

+SCN1Bchr19

35523432

+
intron-3CDSENST00000422945ENST00000262631PPP2R5Cchr14

102276373

+SCN1Bchr19

35523432

+
intron-3CDSENST00000422945ENST00000415950PPP2R5Cchr14

102276373

+SCN1Bchr19

35523432

+
intron-3CDSENST00000422945ENST00000595652PPP2R5Cchr14

102276373

+SCN1Bchr19

35523432

+
intron-3CDSENST00000554442ENST00000262631PPP2R5Cchr14

102276373

+SCN1Bchr19

35523432

+
intron-3CDSENST00000554442ENST00000415950PPP2R5Cchr14

102276373

+SCN1Bchr19

35523432

+
intron-3CDSENST00000554442ENST00000595652PPP2R5Cchr14

102276373

+SCN1Bchr19

35523432

+
intron-3CDSENST00000556068ENST00000262631PPP2R5Cchr14

102276373

+SCN1Bchr19

35523432

+
intron-3CDSENST00000556068ENST00000415950PPP2R5Cchr14

102276373

+SCN1Bchr19

35523432

+
intron-3CDSENST00000556068ENST00000595652PPP2R5Cchr14

102276373

+SCN1Bchr19

35523432

+
intron-3CDSENST00000556260ENST00000262631PPP2R5Cchr14

102276373

+SCN1Bchr19

35523432

+
intron-3CDSENST00000556260ENST00000415950PPP2R5Cchr14

102276373

+SCN1Bchr19

35523432

+
intron-3CDSENST00000556260ENST00000595652PPP2R5Cchr14

102276373

+SCN1Bchr19

35523432

+
intron-3UTRENST00000328724ENST00000596348PPP2R5Cchr14

102276373

+SCN1Bchr19

35523432

+
intron-3UTRENST00000422945ENST00000596348PPP2R5Cchr14

102276373

+SCN1Bchr19

35523432

+
intron-3UTRENST00000554442ENST00000596348PPP2R5Cchr14

102276373

+SCN1Bchr19

35523432

+
intron-3UTRENST00000556068ENST00000596348PPP2R5Cchr14

102276373

+SCN1Bchr19

35523432

+
intron-3UTRENST00000556260ENST00000596348PPP2R5Cchr14

102276373

+SCN1Bchr19

35523432

+

check buttonORFfinder result based on the fusion transcript sequence of in-frame fusion genes.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandSeq length
(transcript)		BP loci
(transcript)		Predicted start
(transcript)		Predicted stop
(transcript)		Seq length
(amino acids)
ENST00000350249PPP2R5Cchr14102276373+ENST00000262631SCN1Bchr1935523432+15082341453239404
ENST00000350249PPP2R5Cchr14102276373+ENST00000595652SCN1Bchr1935523432+920234140637165
ENST00000350249PPP2R5Cchr14102276373+ENST00000415950SCN1Bchr1935523432+11732341401000286
ENST00000445439PPP2R5Cchr14102276373+ENST00000262631SCN1Bchr1935523432+14161421361147404
ENST00000445439PPP2R5Cchr14102276373+ENST00000595652SCN1Bchr1935523432+82814248545165
ENST00000445439PPP2R5Cchr14102276373+ENST00000415950SCN1Bchr1935523432+108114248908286
ENST00000334743PPP2R5Cchr14102276373+ENST00000262631SCN1Bchr1935523432+14161421361147404
ENST00000334743PPP2R5Cchr14102276373+ENST00000595652SCN1Bchr1935523432+82814248545165
ENST00000334743PPP2R5Cchr14102276373+ENST00000415950SCN1Bchr1935523432+108114248908286
ENST00000557095PPP2R5Cchr14102276373+ENST00000262631SCN1Bchr1935523432+14061321351137404
ENST00000557095PPP2R5Cchr14102276373+ENST00000595652SCN1Bchr1935523432+81813238535165
ENST00000557095PPP2R5Cchr14102276373+ENST00000415950SCN1Bchr1935523432+107113238898286
ENST00000556946PPP2R5Cchr14102276373+ENST00000262631SCN1Bchr1935523432+14762021421207404
ENST00000556946PPP2R5Cchr14102276373+ENST00000595652SCN1Bchr1935523432+888202108605165
ENST00000556946PPP2R5Cchr14102276373+ENST00000415950SCN1Bchr1935523432+1141202108968286
ENST00000557714PPP2R5Cchr14102276373+ENST00000262631SCN1Bchr1935523432+14421681387173404
ENST00000557714PPP2R5Cchr14102276373+ENST00000595652SCN1Bchr1935523432+85416874571165
ENST00000557714PPP2R5Cchr14102276373+ENST00000415950SCN1Bchr1935523432+110716874934286

check buttonDeepORF prediction of the coding potential based on the fusion transcript sequence of in-frame fusion genes. DeepORF is a coding potential classifier based on convolutional neural network by comparing the real Ribo-seq data. If the no-coding score < 0.5 and coding score > 0.5, then the in-frame fusion transcript is predicted as being likely translated.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandNo-coding scoreCoding score
ENST00000350249ENST00000262631PPP2R5Cchr14102276373+SCN1Bchr1935523432+0.0038309050.99616903
ENST00000350249ENST00000595652PPP2R5Cchr14102276373+SCN1Bchr1935523432+0.0052539670.9947461
ENST00000350249ENST00000415950PPP2R5Cchr14102276373+SCN1Bchr1935523432+0.078206820.92179316
ENST00000445439ENST00000262631PPP2R5Cchr14102276373+SCN1Bchr1935523432+0.0032367940.9967632
ENST00000445439ENST00000595652PPP2R5Cchr14102276373+SCN1Bchr1935523432+0.0041431870.9958568
ENST00000445439ENST00000415950PPP2R5Cchr14102276373+SCN1Bchr1935523432+0.064541960.93545806
ENST00000334743ENST00000262631PPP2R5Cchr14102276373+SCN1Bchr1935523432+0.0032367940.9967632
ENST00000334743ENST00000595652PPP2R5Cchr14102276373+SCN1Bchr1935523432+0.0041431870.9958568
ENST00000334743ENST00000415950PPP2R5Cchr14102276373+SCN1Bchr1935523432+0.064541960.93545806
ENST00000557095ENST00000262631PPP2R5Cchr14102276373+SCN1Bchr1935523432+0.0032321450.9967679
ENST00000557095ENST00000595652PPP2R5Cchr14102276373+SCN1Bchr1935523432+0.0044492670.99555075
ENST00000557095ENST00000415950PPP2R5Cchr14102276373+SCN1Bchr1935523432+0.067775030.932225
ENST00000556946ENST00000262631PPP2R5Cchr14102276373+SCN1Bchr1935523432+0.0039547950.9960452
ENST00000556946ENST00000595652PPP2R5Cchr14102276373+SCN1Bchr1935523432+0.0056538730.9943461
ENST00000556946ENST00000415950PPP2R5Cchr14102276373+SCN1Bchr1935523432+0.0689161350.9310838
ENST00000557714ENST00000262631PPP2R5Cchr14102276373+SCN1Bchr1935523432+0.0032288040.99677116
ENST00000557714ENST00000595652PPP2R5Cchr14102276373+SCN1Bchr1935523432+0.0040771330.9959229
ENST00000557714ENST00000415950PPP2R5Cchr14102276373+SCN1Bchr1935523432+0.0624792950.9375207

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Fusion Genomic Features for PPP2R5C-SCN1B


check buttonFusionAI prediction of the potential fusion gene breakpoint based on the pre-mature RNA sequence context (+/- 5kb of individual partner genes, total 20kb length sequence). FusionAI is a fusion gene breakpoint classifier based on convolutional neural network by comparing the fusion positive and negative sequence context of ~ 20K fusion gene data. From here, we can have the relative potentency of the 20K genomic sequence how individual sequnce will be likely used as the gene fusion breakpoints.
HgeneHchrHbpHstrandTgeneTchrTbpTstrand1-pp (fusion gene breakpoint)
PPP2R5Cchr14102276373+SCN1Bchr1935523431+1.75E-081
PPP2R5Cchr14102276373+SCN1Bchr1935523431+1.75E-081

check buttonDistribution of 44 human genomic features loci across 20kb length fusion breakpoint regions. We integrated a total of 44 different types of human genomic feature loci information across five big categories including virus integration sites, repeats, structural variants, chromatin states, and gene expression regulation. More details are in help page.
genomic feature

check buttonDistribution of 44 human genomic features loci across 20kb length fusion breakpoint regions that are ovelapped with the top 1% feature importance score regions. More details are in help page.
genomic feature of top 1%

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Fusion Protein Features for PPP2R5C-SCN1B


check button Four levels of functional features of fusion genes
Go to FGviewer search page for the most frequent breakpoint (https://ccsmweb.uth.edu/FGviewer/chr14:102276373/chr19:35523432)
- FGviewer provides the online visualization of the retention search of the protein functional features across DNA, RNA, protein, and pathological levels.
- How to search
1. Put your fusion gene symbol.
2. Press the tab key until there will be shown the breakpoint information filled.
4. Go down and press 'Search' tab twice.
4. Go down to have the hyperlink of the search result.
5. Click the hyperlink.
6. See the FGviewer result for your fusion gene.
FGviewer

check buttonMain function of each fusion partner protein. (from UniProt)
HgeneTgene
..
FUNCTION: Transcriptional activator which is required for calcium-dependent dendritic growth and branching in cortical neurons. Recruits CREB-binding protein (CREBBP) to nuclear bodies. Component of the CREST-BRG1 complex, a multiprotein complex that regulates promoter activation by orchestrating a calcium-dependent release of a repressor complex and a recruitment of an activator complex. In resting neurons, transcription of the c-FOS promoter is inhibited by BRG1-dependent recruitment of a phospho-RB1-HDAC1 repressor complex. Upon calcium influx, RB1 is dephosphorylated by calcineurin, which leads to release of the repressor complex. At the same time, there is increased recruitment of CREBBP to the promoter by a CREST-dependent mechanism, which leads to transcriptional activation. The CREST-BRG1 complex also binds to the NR2B promoter, and activity-dependent induction of NR2B expression involves a release of HDAC1 and recruitment of CREBBP (By similarity). {ECO:0000250}.FUNCTION: Transcriptional activator which is required for calcium-dependent dendritic growth and branching in cortical neurons. Recruits CREB-binding protein (CREBBP) to nuclear bodies. Component of the CREST-BRG1 complex, a multiprotein complex that regulates promoter activation by orchestrating a calcium-dependent release of a repressor complex and a recruitment of an activator complex. In resting neurons, transcription of the c-FOS promoter is inhibited by BRG1-dependent recruitment of a phospho-RB1-HDAC1 repressor complex. Upon calcium influx, RB1 is dephosphorylated by calcineurin, which leads to release of the repressor complex. At the same time, there is increased recruitment of CREBBP to the promoter by a CREST-dependent mechanism, which leads to transcriptional activation. The CREST-BRG1 complex also binds to the NR2B promoter, and activity-dependent induction of NR2B expression involves a release of HDAC1 and recruitment of CREBBP (By similarity). {ECO:0000250}.

check buttonRetention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at

download page


* Minus value of BPloci means that the break pointn is located before the CDS.
- In-frame and retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
TgeneSCN1Bchr14:102276373chr19:35523432ENST000002626310622_15013377.3333333333333DomainNote=Ig-like C2-type
TgeneSCN1Bchr14:102276373chr19:35523432ENST000004159500322_15013269.0DomainNote=Ig-like C2-type
TgeneSCN1Bchr14:102276373chr19:35523432ENST0000026263106183_21813377.3333333333333Topological domainCytoplasmic
TgeneSCN1Bchr14:102276373chr19:35523432ENST000002626310619_16013377.3333333333333Topological domainExtracellular
TgeneSCN1Bchr14:102276373chr19:35523432ENST0000041595003183_21813269.0Topological domainCytoplasmic
TgeneSCN1Bchr14:102276373chr19:35523432ENST000004159500319_16013269.0Topological domainExtracellular
TgeneSCN1Bchr14:102276373chr19:35523432ENST0000026263106161_18213377.3333333333333TransmembraneHelical
TgeneSCN1Bchr14:102276373chr19:35523432ENST0000041595003161_18213269.0TransmembraneHelical

- In-frame and not-retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
HgenePPP2R5Cchr14:102276373chr19:35523432ENST00000328724+115416_4220541.0MotifNuclear localization signal
HgenePPP2R5Cchr14:102276373chr19:35523432ENST00000334743+114416_42231525.0MotifNuclear localization signal
HgenePPP2R5Cchr14:102276373chr19:35523432ENST00000350249+113416_42231486.0MotifNuclear localization signal
HgenePPP2R5Cchr14:102276373chr19:35523432ENST00000422945+116416_4220556.0MotifNuclear localization signal
HgenePPP2R5Cchr14:102276373chr19:35523432ENST00000445439+112416_42231450.0MotifNuclear localization signal


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Fusion Gene Sequence for PPP2R5C-SCN1B


check button For in-frame fusion transcripts, we provide the fusion transcript sequences and fusion amino acid sequences. To have fusion amino acid sequence, we ran ORFfinder and chose the longest ORF among the all predicted ones.
>68084_68084_1_PPP2R5C-SCN1B_PPP2R5C_chr14_102276373_ENST00000334743_SCN1B_chr19_35523432_ENST00000262631_length(transcript)=1416nt_BP=142nt
CTGGTTTCTTGCCTTAAGGAGCCCATTGCCTTTCCCGCTGAAGTCTAGATGTTGACATGTAATAAAGCGGGCAGCAGGATGGTGGTGGAT
GCGGCCAACTCCAATGGGCCTTTCCAGCCCGTGGTCCTTCTCCATATTCGAGTGTCCTCAGCCTGCGGGGGCTGCGTGGAGGTGGACTCG
GAGACCGAGGCCGTGTATGGGATGACCTTCAAAATTCTTTGCATCTCCTGCAAGCGCCGCAGCGAGACCAACGCTGAGACCTTCACCGAG
TGGACCTTCCGCCAGAAGGGCACTGAGGAGTTTGTCAAGATCCTGCGCTATGAGAATGAGGTGTTGCAGCTGGAGGAGGATGAGCGCTTC
GAGGGCCGCGTGGTGTGGAATGGCAGCCGGGGCACCAAAGACCTGCAGGATCTGTCTATCTTCATCACCAATGTCACCTACAACCACTCG
GGCGACTACGAGTGCCACGTCTACCGCCTGCTCTTCTTCGAAAACTACGAGCACAACACCAGCGTCGTCAAGAAGATCCACATTGAGGTA
GTGGACAAAGCCAACAGAGACATGGCATCCATCGTGTCTGAGATCATGATGTATGTGCTCATTGTGGTGTTGACCATATGGCTCGTGGCA
GAGATGATTTACTGCTACAAGAAGATCGCTGCCGCCACGGAGACTGCTGCACAGGAGAATGCCTCGGAATACCTGGCCATCACCTCTGAA
AGCAAAGAGAACTGCACGGGCGTCCAGGTGGCCGAATAGCCCTGGCCCTGGGCCCCGCCTCAAGGAAGAGCCAGCCGTAATGGGGACTCT
CCAGGCACCGCCTGCCCCCAGCGTGGGGGTGGCCACTCCTGGGCCCCAGAAAGCCTCAGAGTCCTGCCGACGGAGCCACTGGGGTGGGAG
GGGGCAGGGGGCTTGGCTCGCACCCCCACTTTCGCCTCCTCCAGCTCCTGCCCCGCCGGCCGCGCACCGCCATGCATGATGGGTAAAGCA
ATACTGCCGCTGCCCCCACCCTGCTTCTGCTGCCTGTTTGGGGAGGGGGGCGGTGAGGTGGGGGCAGCGGCCCCGCACCCCTCCTCCTTG
CTGATTTGCACACATTGGCCGCTTCAGACACGCACTTCTGGGGCCAGCCCCTCCCCGCCTCCTCCCTGCCTGGCGGCAGGGGTCGCGATG
ATGGGCTGGAGCAGTTTGGGGCAGGGGGTTCTGGGACCCACTCCGACTCCCCCTCCCCGGCATCATTTCCCCTCCCGCTTCCTCCGGCTG
GACCTGGGGTCCCCCCTCCCTGTAATGCACTCCTGCCCCGGCCCAACCTCGCCCTCTCTCACCAGCCTTGAACTGTGGCCACCTAGAAAG

>68084_68084_1_PPP2R5C-SCN1B_PPP2R5C_chr14_102276373_ENST00000334743_SCN1B_chr19_35523432_ENST00000262631_length(amino acids)=404AA_BP=1
MNGPLSRWPQFKAGERGRGWAGAGVHYREGGPQVQPEEAGGEMMPGRGSRSGSQNPLPQTAPAHHRDPCRQAGRRRGGAGPRSACLKRPM
CANQQGGGVRGRCPHLTAPLPKQAAEAGWGQRQYCFTHHAWRCAAGGAGAGGGESGGASQAPCPLPPQWLRRQDSEAFWGPGVATPTLGA
GGAWRVPITAGSSLRRGPGPGLFGHLDARAVLFAFRGDGQVFRGILLCSSLRGGSDLLVAVNHLCHEPYGQHHNEHIHHDLRHDGCHVSV
GFVHYLNVDLLDDAGVVLVVFEEEQAVDVALVVARVVVGDIGDEDRQILQVFGAPAAIPHHAALEALILLQLQHLILIAQDLDKLLSALL

--------------------------------------------------------------
>68084_68084_2_PPP2R5C-SCN1B_PPP2R5C_chr14_102276373_ENST00000334743_SCN1B_chr19_35523432_ENST00000415950_length(transcript)=1081nt_BP=142nt
CTGGTTTCTTGCCTTAAGGAGCCCATTGCCTTTCCCGCTGAAGTCTAGATGTTGACATGTAATAAAGCGGGCAGCAGGATGGTGGTGGAT
GCGGCCAACTCCAATGGGCCTTTCCAGCCCGTGGTCCTTCTCCATATTCGAGTGTCCTCAGCCTGCGGGGGCTGCGTGGAGGTGGACTCG
GAGACCGAGGCCGTGTATGGGATGACCTTCAAAATTCTTTGCATCTCCTGCAAGCGCCGCAGCGAGACCAACGCTGAGACCTTCACCGAG
TGGACCTTCCGCCAGAAGGGCACTGAGGAGTTTGTCAAGATCCTGCGCTATGAGAATGAGGTGTTGCAGCTGGAGGAGGATGAGCGCTTC
GAGGGCCGCGTGGTGTGGAATGGCAGCCGGGGCACCAAAGACCTGCAGGATCTGTCTATCTTCATCACCAATGTCACCTACAACCACTCG
GGCGACTACGAGTGCCACGTCTACCGCCTGCTCTTCTTCGAAAACTACGAGCACAACACCAGCGTCGTCAAGAAGATCCACATTGAGGTA
GTGGACAAAGGTGAGTCGGGTGCTGCCTGCCCCTTTACCGTCACCCACCGGAGAGCCAGATGGAGGGACAGATGGCAGGCAGTGGACAGG
ACAGGCTGGCTCTGTGCCTGGCCAGCCAACCGCCCACAGCAGCGGGCTGAGGGGGAGGGGAGCAGCCCCTCCTGCCCACTCCAGCTCTGG
CCTCTGTTTCTCTCCAGCCCACGGAGAGGTCAAAGCATGCCTGTCCCCCACAGACGCTCCGGGTACAGAACCCAGCTCTGTCACCTGTGC
TGTATGACCTCTGGCAGGTGCCTTCTGTCTCTGAGCCAAAGGGTTGTCCTGGGCTTGCCCGGGATAATAATCCGATGTGTTTCTCGGGGT
GTGGTTTGAGCCATTCTTCCATCATGGGGTTCATGAGGATTGAGCAGCTGCAGGCACACGCCTGGCTTCCAGCAGAGCCTTGCAGGTGGT
GGCGAGGGTGGCGGTTCTTACTGTTCGAGTAGCTCAGCCCTGCTGCCCTCTGTGGTGATGAGGCAAGAGAGCGTGCCACCTAGAGCAGAG

>68084_68084_2_PPP2R5C-SCN1B_PPP2R5C_chr14_102276373_ENST00000334743_SCN1B_chr19_35523432_ENST00000415950_length(amino acids)=286AA_BP=31
MLTCNKAGSRMVVDAANSNGPFQPVVLLHIRVSSACGGCVEVDSETEAVYGMTFKILCISCKRRSETNAETFTEWTFRQKGTEEFVKILR
YENEVLQLEEDERFEGRVVWNGSRGTKDLQDLSIFITNVTYNHSGDYECHVYRLLFFENYEHNTSVVKKIHIEVVDKGESGAACPFTVTH
RRARWRDRWQAVDRTGWLCAWPANRPQQRAEGEGSSPSCPLQLWPLFLSSPRRGQSMPVPHRRSGYRTQLCHLCCMTSGRCLLSLSQRVV

--------------------------------------------------------------
>68084_68084_3_PPP2R5C-SCN1B_PPP2R5C_chr14_102276373_ENST00000334743_SCN1B_chr19_35523432_ENST00000595652_length(transcript)=828nt_BP=142nt
CTGGTTTCTTGCCTTAAGGAGCCCATTGCCTTTCCCGCTGAAGTCTAGATGTTGACATGTAATAAAGCGGGCAGCAGGATGGTGGTGGAT
GCGGCCAACTCCAATGGGCCTTTCCAGCCCGTGGTCCTTCTCCATATTCGAGTGTCCTCAGCCTGCGGGGGCTGCGTGGAGGTGGACTCG
GAGACCGAGGCCGTGTATGGGATGACCTTCAAAATTCTTTGCATCTCCTGCAAGCGCCGCAGCGAGACCAACGCTGAGACCTTCACCGAG
TGGACCTTCCGCCAGAAGGGCACTGAGGAGTTTGTCAAGAAGATCCACATTGAGGTAGTGGACAAAGCCAACAGAGACATGGCATCCATC
GTGTCTGAGATCATGATGTATGTGCTCATTGTGGTGTTGACCATATGGCTCGTGGCAGAGATGATTTACTGCTACAAGAAGATCGCTGCC
GCCACGGAGACTGCTGCACAGGAGAATGCCTCGGAATACCTGGCCATCACCTCTGAAAGCAAAGAGAACTGCACGGGCGTCCAGGTGGCC
GAATAGCCCTGGCCCTGGGCCCCGCCTCAAGGAAGAGCCAGCCGTAATGGGGACTCTCCAGGCACCGCCTGCCCCCAGCGTGGGGGTGGC
CACTCCTGGGCCCCAGAAAGCCTCAGAGTCCTGCCGACGGAGCCACTGGGGTGGGAGGGGGCAGGGGGCTTGGCTCGCACCCCCACTTTC
GCCTCCTCCAGCTCCTGCCCCGCCGGCCGCGCACCGCCATGCATGATGGGTAAAGCAATACTGCCGCTGCCCCCACCCTGCTTCTGCTGC

>68084_68084_3_PPP2R5C-SCN1B_PPP2R5C_chr14_102276373_ENST00000334743_SCN1B_chr19_35523432_ENST00000595652_length(amino acids)=165AA_BP=31
MLTCNKAGSRMVVDAANSNGPFQPVVLLHIRVSSACGGCVEVDSETEAVYGMTFKILCISCKRRSETNAETFTEWTFRQKGTEEFVKKIH

--------------------------------------------------------------
>68084_68084_4_PPP2R5C-SCN1B_PPP2R5C_chr14_102276373_ENST00000350249_SCN1B_chr19_35523432_ENST00000262631_length(transcript)=1508nt_BP=234nt
AGCTTCATGCCTGCTGACATCACGAACCAGCCAGTTCCCTCCAGCTGCAGAGAGCTTCAGTTTGTCTTTTTTTTTTTAAACTAAAATGGA
GGCTGGTTTCTTGCCTTAAGGAGCCCATTGCCTTTCCCGCTGAAGTCTAGATGTTGACATGTAATAAAGCGGGCAGCAGGATGGTGGTGG
ATGCGGCCAACTCCAATGGGCCTTTCCAGCCCGTGGTCCTTCTCCATATTCGAGTGTCCTCAGCCTGCGGGGGCTGCGTGGAGGTGGACT
CGGAGACCGAGGCCGTGTATGGGATGACCTTCAAAATTCTTTGCATCTCCTGCAAGCGCCGCAGCGAGACCAACGCTGAGACCTTCACCG
AGTGGACCTTCCGCCAGAAGGGCACTGAGGAGTTTGTCAAGATCCTGCGCTATGAGAATGAGGTGTTGCAGCTGGAGGAGGATGAGCGCT
TCGAGGGCCGCGTGGTGTGGAATGGCAGCCGGGGCACCAAAGACCTGCAGGATCTGTCTATCTTCATCACCAATGTCACCTACAACCACT
CGGGCGACTACGAGTGCCACGTCTACCGCCTGCTCTTCTTCGAAAACTACGAGCACAACACCAGCGTCGTCAAGAAGATCCACATTGAGG
TAGTGGACAAAGCCAACAGAGACATGGCATCCATCGTGTCTGAGATCATGATGTATGTGCTCATTGTGGTGTTGACCATATGGCTCGTGG
CAGAGATGATTTACTGCTACAAGAAGATCGCTGCCGCCACGGAGACTGCTGCACAGGAGAATGCCTCGGAATACCTGGCCATCACCTCTG
AAAGCAAAGAGAACTGCACGGGCGTCCAGGTGGCCGAATAGCCCTGGCCCTGGGCCCCGCCTCAAGGAAGAGCCAGCCGTAATGGGGACT
CTCCAGGCACCGCCTGCCCCCAGCGTGGGGGTGGCCACTCCTGGGCCCCAGAAAGCCTCAGAGTCCTGCCGACGGAGCCACTGGGGTGGG
AGGGGGCAGGGGGCTTGGCTCGCACCCCCACTTTCGCCTCCTCCAGCTCCTGCCCCGCCGGCCGCGCACCGCCATGCATGATGGGTAAAG
CAATACTGCCGCTGCCCCCACCCTGCTTCTGCTGCCTGTTTGGGGAGGGGGGCGGTGAGGTGGGGGCAGCGGCCCCGCACCCCTCCTCCT
TGCTGATTTGCACACATTGGCCGCTTCAGACACGCACTTCTGGGGCCAGCCCCTCCCCGCCTCCTCCCTGCCTGGCGGCAGGGGTCGCGA
TGATGGGCTGGAGCAGTTTGGGGCAGGGGGTTCTGGGACCCACTCCGACTCCCCCTCCCCGGCATCATTTCCCCTCCCGCTTCCTCCGGC
TGGACCTGGGGTCCCCCCTCCCTGTAATGCACTCCTGCCCCGGCCCAACCTCGCCCTCTCTCACCAGCCTTGAACTGTGGCCACCTAGAA

>68084_68084_4_PPP2R5C-SCN1B_PPP2R5C_chr14_102276373_ENST00000350249_SCN1B_chr19_35523432_ENST00000262631_length(amino acids)=404AA_BP=1
MNGPLSRWPQFKAGERGRGWAGAGVHYREGGPQVQPEEAGGEMMPGRGSRSGSQNPLPQTAPAHHRDPCRQAGRRRGGAGPRSACLKRPM
CANQQGGGVRGRCPHLTAPLPKQAAEAGWGQRQYCFTHHAWRCAAGGAGAGGGESGGASQAPCPLPPQWLRRQDSEAFWGPGVATPTLGA
GGAWRVPITAGSSLRRGPGPGLFGHLDARAVLFAFRGDGQVFRGILLCSSLRGGSDLLVAVNHLCHEPYGQHHNEHIHHDLRHDGCHVSV
GFVHYLNVDLLDDAGVVLVVFEEEQAVDVALVVARVVVGDIGDEDRQILQVFGAPAAIPHHAALEALILLQLQHLILIAQDLDKLLSALL

--------------------------------------------------------------
>68084_68084_5_PPP2R5C-SCN1B_PPP2R5C_chr14_102276373_ENST00000350249_SCN1B_chr19_35523432_ENST00000415950_length(transcript)=1173nt_BP=234nt
AGCTTCATGCCTGCTGACATCACGAACCAGCCAGTTCCCTCCAGCTGCAGAGAGCTTCAGTTTGTCTTTTTTTTTTTAAACTAAAATGGA
GGCTGGTTTCTTGCCTTAAGGAGCCCATTGCCTTTCCCGCTGAAGTCTAGATGTTGACATGTAATAAAGCGGGCAGCAGGATGGTGGTGG
ATGCGGCCAACTCCAATGGGCCTTTCCAGCCCGTGGTCCTTCTCCATATTCGAGTGTCCTCAGCCTGCGGGGGCTGCGTGGAGGTGGACT
CGGAGACCGAGGCCGTGTATGGGATGACCTTCAAAATTCTTTGCATCTCCTGCAAGCGCCGCAGCGAGACCAACGCTGAGACCTTCACCG
AGTGGACCTTCCGCCAGAAGGGCACTGAGGAGTTTGTCAAGATCCTGCGCTATGAGAATGAGGTGTTGCAGCTGGAGGAGGATGAGCGCT
TCGAGGGCCGCGTGGTGTGGAATGGCAGCCGGGGCACCAAAGACCTGCAGGATCTGTCTATCTTCATCACCAATGTCACCTACAACCACT
CGGGCGACTACGAGTGCCACGTCTACCGCCTGCTCTTCTTCGAAAACTACGAGCACAACACCAGCGTCGTCAAGAAGATCCACATTGAGG
TAGTGGACAAAGGTGAGTCGGGTGCTGCCTGCCCCTTTACCGTCACCCACCGGAGAGCCAGATGGAGGGACAGATGGCAGGCAGTGGACA
GGACAGGCTGGCTCTGTGCCTGGCCAGCCAACCGCCCACAGCAGCGGGCTGAGGGGGAGGGGAGCAGCCCCTCCTGCCCACTCCAGCTCT
GGCCTCTGTTTCTCTCCAGCCCACGGAGAGGTCAAAGCATGCCTGTCCCCCACAGACGCTCCGGGTACAGAACCCAGCTCTGTCACCTGT
GCTGTATGACCTCTGGCAGGTGCCTTCTGTCTCTGAGCCAAAGGGTTGTCCTGGGCTTGCCCGGGATAATAATCCGATGTGTTTCTCGGG
GTGTGGTTTGAGCCATTCTTCCATCATGGGGTTCATGAGGATTGAGCAGCTGCAGGCACACGCCTGGCTTCCAGCAGAGCCTTGCAGGTG
GTGGCGAGGGTGGCGGTTCTTACTGTTCGAGTAGCTCAGCCCTGCTGCCCTCTGTGGTGATGAGGCAAGAGAGCGTGCCACCTAGAGCAG

>68084_68084_5_PPP2R5C-SCN1B_PPP2R5C_chr14_102276373_ENST00000350249_SCN1B_chr19_35523432_ENST00000415950_length(amino acids)=286AA_BP=31
MLTCNKAGSRMVVDAANSNGPFQPVVLLHIRVSSACGGCVEVDSETEAVYGMTFKILCISCKRRSETNAETFTEWTFRQKGTEEFVKILR
YENEVLQLEEDERFEGRVVWNGSRGTKDLQDLSIFITNVTYNHSGDYECHVYRLLFFENYEHNTSVVKKIHIEVVDKGESGAACPFTVTH
RRARWRDRWQAVDRTGWLCAWPANRPQQRAEGEGSSPSCPLQLWPLFLSSPRRGQSMPVPHRRSGYRTQLCHLCCMTSGRCLLSLSQRVV

--------------------------------------------------------------
>68084_68084_6_PPP2R5C-SCN1B_PPP2R5C_chr14_102276373_ENST00000350249_SCN1B_chr19_35523432_ENST00000595652_length(transcript)=920nt_BP=234nt
AGCTTCATGCCTGCTGACATCACGAACCAGCCAGTTCCCTCCAGCTGCAGAGAGCTTCAGTTTGTCTTTTTTTTTTTAAACTAAAATGGA
GGCTGGTTTCTTGCCTTAAGGAGCCCATTGCCTTTCCCGCTGAAGTCTAGATGTTGACATGTAATAAAGCGGGCAGCAGGATGGTGGTGG
ATGCGGCCAACTCCAATGGGCCTTTCCAGCCCGTGGTCCTTCTCCATATTCGAGTGTCCTCAGCCTGCGGGGGCTGCGTGGAGGTGGACT
CGGAGACCGAGGCCGTGTATGGGATGACCTTCAAAATTCTTTGCATCTCCTGCAAGCGCCGCAGCGAGACCAACGCTGAGACCTTCACCG
AGTGGACCTTCCGCCAGAAGGGCACTGAGGAGTTTGTCAAGAAGATCCACATTGAGGTAGTGGACAAAGCCAACAGAGACATGGCATCCA
TCGTGTCTGAGATCATGATGTATGTGCTCATTGTGGTGTTGACCATATGGCTCGTGGCAGAGATGATTTACTGCTACAAGAAGATCGCTG
CCGCCACGGAGACTGCTGCACAGGAGAATGCCTCGGAATACCTGGCCATCACCTCTGAAAGCAAAGAGAACTGCACGGGCGTCCAGGTGG
CCGAATAGCCCTGGCCCTGGGCCCCGCCTCAAGGAAGAGCCAGCCGTAATGGGGACTCTCCAGGCACCGCCTGCCCCCAGCGTGGGGGTG
GCCACTCCTGGGCCCCAGAAAGCCTCAGAGTCCTGCCGACGGAGCCACTGGGGTGGGAGGGGGCAGGGGGCTTGGCTCGCACCCCCACTT
TCGCCTCCTCCAGCTCCTGCCCCGCCGGCCGCGCACCGCCATGCATGATGGGTAAAGCAATACTGCCGCTGCCCCCACCCTGCTTCTGCT

>68084_68084_6_PPP2R5C-SCN1B_PPP2R5C_chr14_102276373_ENST00000350249_SCN1B_chr19_35523432_ENST00000595652_length(amino acids)=165AA_BP=31
MLTCNKAGSRMVVDAANSNGPFQPVVLLHIRVSSACGGCVEVDSETEAVYGMTFKILCISCKRRSETNAETFTEWTFRQKGTEEFVKKIH

--------------------------------------------------------------
>68084_68084_7_PPP2R5C-SCN1B_PPP2R5C_chr14_102276373_ENST00000445439_SCN1B_chr19_35523432_ENST00000262631_length(transcript)=1416nt_BP=142nt
CTGGTTTCTTGCCTTAAGGAGCCCATTGCCTTTCCCGCTGAAGTCTAGATGTTGACATGTAATAAAGCGGGCAGCAGGATGGTGGTGGAT
GCGGCCAACTCCAATGGGCCTTTCCAGCCCGTGGTCCTTCTCCATATTCGAGTGTCCTCAGCCTGCGGGGGCTGCGTGGAGGTGGACTCG
GAGACCGAGGCCGTGTATGGGATGACCTTCAAAATTCTTTGCATCTCCTGCAAGCGCCGCAGCGAGACCAACGCTGAGACCTTCACCGAG
TGGACCTTCCGCCAGAAGGGCACTGAGGAGTTTGTCAAGATCCTGCGCTATGAGAATGAGGTGTTGCAGCTGGAGGAGGATGAGCGCTTC
GAGGGCCGCGTGGTGTGGAATGGCAGCCGGGGCACCAAAGACCTGCAGGATCTGTCTATCTTCATCACCAATGTCACCTACAACCACTCG
GGCGACTACGAGTGCCACGTCTACCGCCTGCTCTTCTTCGAAAACTACGAGCACAACACCAGCGTCGTCAAGAAGATCCACATTGAGGTA
GTGGACAAAGCCAACAGAGACATGGCATCCATCGTGTCTGAGATCATGATGTATGTGCTCATTGTGGTGTTGACCATATGGCTCGTGGCA
GAGATGATTTACTGCTACAAGAAGATCGCTGCCGCCACGGAGACTGCTGCACAGGAGAATGCCTCGGAATACCTGGCCATCACCTCTGAA
AGCAAAGAGAACTGCACGGGCGTCCAGGTGGCCGAATAGCCCTGGCCCTGGGCCCCGCCTCAAGGAAGAGCCAGCCGTAATGGGGACTCT
CCAGGCACCGCCTGCCCCCAGCGTGGGGGTGGCCACTCCTGGGCCCCAGAAAGCCTCAGAGTCCTGCCGACGGAGCCACTGGGGTGGGAG
GGGGCAGGGGGCTTGGCTCGCACCCCCACTTTCGCCTCCTCCAGCTCCTGCCCCGCCGGCCGCGCACCGCCATGCATGATGGGTAAAGCA
ATACTGCCGCTGCCCCCACCCTGCTTCTGCTGCCTGTTTGGGGAGGGGGGCGGTGAGGTGGGGGCAGCGGCCCCGCACCCCTCCTCCTTG
CTGATTTGCACACATTGGCCGCTTCAGACACGCACTTCTGGGGCCAGCCCCTCCCCGCCTCCTCCCTGCCTGGCGGCAGGGGTCGCGATG
ATGGGCTGGAGCAGTTTGGGGCAGGGGGTTCTGGGACCCACTCCGACTCCCCCTCCCCGGCATCATTTCCCCTCCCGCTTCCTCCGGCTG
GACCTGGGGTCCCCCCTCCCTGTAATGCACTCCTGCCCCGGCCCAACCTCGCCCTCTCTCACCAGCCTTGAACTGTGGCCACCTAGAAAG

>68084_68084_7_PPP2R5C-SCN1B_PPP2R5C_chr14_102276373_ENST00000445439_SCN1B_chr19_35523432_ENST00000262631_length(amino acids)=404AA_BP=1
MNGPLSRWPQFKAGERGRGWAGAGVHYREGGPQVQPEEAGGEMMPGRGSRSGSQNPLPQTAPAHHRDPCRQAGRRRGGAGPRSACLKRPM
CANQQGGGVRGRCPHLTAPLPKQAAEAGWGQRQYCFTHHAWRCAAGGAGAGGGESGGASQAPCPLPPQWLRRQDSEAFWGPGVATPTLGA
GGAWRVPITAGSSLRRGPGPGLFGHLDARAVLFAFRGDGQVFRGILLCSSLRGGSDLLVAVNHLCHEPYGQHHNEHIHHDLRHDGCHVSV
GFVHYLNVDLLDDAGVVLVVFEEEQAVDVALVVARVVVGDIGDEDRQILQVFGAPAAIPHHAALEALILLQLQHLILIAQDLDKLLSALL

--------------------------------------------------------------
>68084_68084_8_PPP2R5C-SCN1B_PPP2R5C_chr14_102276373_ENST00000445439_SCN1B_chr19_35523432_ENST00000415950_length(transcript)=1081nt_BP=142nt
CTGGTTTCTTGCCTTAAGGAGCCCATTGCCTTTCCCGCTGAAGTCTAGATGTTGACATGTAATAAAGCGGGCAGCAGGATGGTGGTGGAT
GCGGCCAACTCCAATGGGCCTTTCCAGCCCGTGGTCCTTCTCCATATTCGAGTGTCCTCAGCCTGCGGGGGCTGCGTGGAGGTGGACTCG
GAGACCGAGGCCGTGTATGGGATGACCTTCAAAATTCTTTGCATCTCCTGCAAGCGCCGCAGCGAGACCAACGCTGAGACCTTCACCGAG
TGGACCTTCCGCCAGAAGGGCACTGAGGAGTTTGTCAAGATCCTGCGCTATGAGAATGAGGTGTTGCAGCTGGAGGAGGATGAGCGCTTC
GAGGGCCGCGTGGTGTGGAATGGCAGCCGGGGCACCAAAGACCTGCAGGATCTGTCTATCTTCATCACCAATGTCACCTACAACCACTCG
GGCGACTACGAGTGCCACGTCTACCGCCTGCTCTTCTTCGAAAACTACGAGCACAACACCAGCGTCGTCAAGAAGATCCACATTGAGGTA
GTGGACAAAGGTGAGTCGGGTGCTGCCTGCCCCTTTACCGTCACCCACCGGAGAGCCAGATGGAGGGACAGATGGCAGGCAGTGGACAGG
ACAGGCTGGCTCTGTGCCTGGCCAGCCAACCGCCCACAGCAGCGGGCTGAGGGGGAGGGGAGCAGCCCCTCCTGCCCACTCCAGCTCTGG
CCTCTGTTTCTCTCCAGCCCACGGAGAGGTCAAAGCATGCCTGTCCCCCACAGACGCTCCGGGTACAGAACCCAGCTCTGTCACCTGTGC
TGTATGACCTCTGGCAGGTGCCTTCTGTCTCTGAGCCAAAGGGTTGTCCTGGGCTTGCCCGGGATAATAATCCGATGTGTTTCTCGGGGT
GTGGTTTGAGCCATTCTTCCATCATGGGGTTCATGAGGATTGAGCAGCTGCAGGCACACGCCTGGCTTCCAGCAGAGCCTTGCAGGTGGT
GGCGAGGGTGGCGGTTCTTACTGTTCGAGTAGCTCAGCCCTGCTGCCCTCTGTGGTGATGAGGCAAGAGAGCGTGCCACCTAGAGCAGAG

>68084_68084_8_PPP2R5C-SCN1B_PPP2R5C_chr14_102276373_ENST00000445439_SCN1B_chr19_35523432_ENST00000415950_length(amino acids)=286AA_BP=31
MLTCNKAGSRMVVDAANSNGPFQPVVLLHIRVSSACGGCVEVDSETEAVYGMTFKILCISCKRRSETNAETFTEWTFRQKGTEEFVKILR
YENEVLQLEEDERFEGRVVWNGSRGTKDLQDLSIFITNVTYNHSGDYECHVYRLLFFENYEHNTSVVKKIHIEVVDKGESGAACPFTVTH
RRARWRDRWQAVDRTGWLCAWPANRPQQRAEGEGSSPSCPLQLWPLFLSSPRRGQSMPVPHRRSGYRTQLCHLCCMTSGRCLLSLSQRVV

--------------------------------------------------------------
>68084_68084_9_PPP2R5C-SCN1B_PPP2R5C_chr14_102276373_ENST00000445439_SCN1B_chr19_35523432_ENST00000595652_length(transcript)=828nt_BP=142nt
CTGGTTTCTTGCCTTAAGGAGCCCATTGCCTTTCCCGCTGAAGTCTAGATGTTGACATGTAATAAAGCGGGCAGCAGGATGGTGGTGGAT
GCGGCCAACTCCAATGGGCCTTTCCAGCCCGTGGTCCTTCTCCATATTCGAGTGTCCTCAGCCTGCGGGGGCTGCGTGGAGGTGGACTCG
GAGACCGAGGCCGTGTATGGGATGACCTTCAAAATTCTTTGCATCTCCTGCAAGCGCCGCAGCGAGACCAACGCTGAGACCTTCACCGAG
TGGACCTTCCGCCAGAAGGGCACTGAGGAGTTTGTCAAGAAGATCCACATTGAGGTAGTGGACAAAGCCAACAGAGACATGGCATCCATC
GTGTCTGAGATCATGATGTATGTGCTCATTGTGGTGTTGACCATATGGCTCGTGGCAGAGATGATTTACTGCTACAAGAAGATCGCTGCC
GCCACGGAGACTGCTGCACAGGAGAATGCCTCGGAATACCTGGCCATCACCTCTGAAAGCAAAGAGAACTGCACGGGCGTCCAGGTGGCC
GAATAGCCCTGGCCCTGGGCCCCGCCTCAAGGAAGAGCCAGCCGTAATGGGGACTCTCCAGGCACCGCCTGCCCCCAGCGTGGGGGTGGC
CACTCCTGGGCCCCAGAAAGCCTCAGAGTCCTGCCGACGGAGCCACTGGGGTGGGAGGGGGCAGGGGGCTTGGCTCGCACCCCCACTTTC
GCCTCCTCCAGCTCCTGCCCCGCCGGCCGCGCACCGCCATGCATGATGGGTAAAGCAATACTGCCGCTGCCCCCACCCTGCTTCTGCTGC

>68084_68084_9_PPP2R5C-SCN1B_PPP2R5C_chr14_102276373_ENST00000445439_SCN1B_chr19_35523432_ENST00000595652_length(amino acids)=165AA_BP=31
MLTCNKAGSRMVVDAANSNGPFQPVVLLHIRVSSACGGCVEVDSETEAVYGMTFKILCISCKRRSETNAETFTEWTFRQKGTEEFVKKIH

--------------------------------------------------------------
>68084_68084_10_PPP2R5C-SCN1B_PPP2R5C_chr14_102276373_ENST00000556946_SCN1B_chr19_35523432_ENST00000262631_length(transcript)=1476nt_BP=202nt
AGTTCCCTCCAGCTGCAGAGAGCTTCAGTTTGTCTTTTTTTTTTTAAACTAAAATGGAGGCTGGTTTCTTGCCTTAAGGAGCCCATTGCC
TTTCCCGCTGAAGTCTAGATGTTGACATGTAATAAAGCGGGCAGCAGGATGGTGGTGGATGCGGCCAACTCCAATGGGCCTTTCCAGCCC
GTGGTCCTTCTCCATATTCGAGTGTCCTCAGCCTGCGGGGGCTGCGTGGAGGTGGACTCGGAGACCGAGGCCGTGTATGGGATGACCTTC
AAAATTCTTTGCATCTCCTGCAAGCGCCGCAGCGAGACCAACGCTGAGACCTTCACCGAGTGGACCTTCCGCCAGAAGGGCACTGAGGAG
TTTGTCAAGATCCTGCGCTATGAGAATGAGGTGTTGCAGCTGGAGGAGGATGAGCGCTTCGAGGGCCGCGTGGTGTGGAATGGCAGCCGG
GGCACCAAAGACCTGCAGGATCTGTCTATCTTCATCACCAATGTCACCTACAACCACTCGGGCGACTACGAGTGCCACGTCTACCGCCTG
CTCTTCTTCGAAAACTACGAGCACAACACCAGCGTCGTCAAGAAGATCCACATTGAGGTAGTGGACAAAGCCAACAGAGACATGGCATCC
ATCGTGTCTGAGATCATGATGTATGTGCTCATTGTGGTGTTGACCATATGGCTCGTGGCAGAGATGATTTACTGCTACAAGAAGATCGCT
GCCGCCACGGAGACTGCTGCACAGGAGAATGCCTCGGAATACCTGGCCATCACCTCTGAAAGCAAAGAGAACTGCACGGGCGTCCAGGTG
GCCGAATAGCCCTGGCCCTGGGCCCCGCCTCAAGGAAGAGCCAGCCGTAATGGGGACTCTCCAGGCACCGCCTGCCCCCAGCGTGGGGGT
GGCCACTCCTGGGCCCCAGAAAGCCTCAGAGTCCTGCCGACGGAGCCACTGGGGTGGGAGGGGGCAGGGGGCTTGGCTCGCACCCCCACT
TTCGCCTCCTCCAGCTCCTGCCCCGCCGGCCGCGCACCGCCATGCATGATGGGTAAAGCAATACTGCCGCTGCCCCCACCCTGCTTCTGC
TGCCTGTTTGGGGAGGGGGGCGGTGAGGTGGGGGCAGCGGCCCCGCACCCCTCCTCCTTGCTGATTTGCACACATTGGCCGCTTCAGACA
CGCACTTCTGGGGCCAGCCCCTCCCCGCCTCCTCCCTGCCTGGCGGCAGGGGTCGCGATGATGGGCTGGAGCAGTTTGGGGCAGGGGGTT
CTGGGACCCACTCCGACTCCCCCTCCCCGGCATCATTTCCCCTCCCGCTTCCTCCGGCTGGACCTGGGGTCCCCCCTCCCTGTAATGCAC
TCCTGCCCCGGCCCAACCTCGCCCTCTCTCACCAGCCTTGAACTGTGGCCACCTAGAAAGGGGCCCATTCAGCCTCGTCTCTTTACAGAA

>68084_68084_10_PPP2R5C-SCN1B_PPP2R5C_chr14_102276373_ENST00000556946_SCN1B_chr19_35523432_ENST00000262631_length(amino acids)=404AA_BP=1
MNGPLSRWPQFKAGERGRGWAGAGVHYREGGPQVQPEEAGGEMMPGRGSRSGSQNPLPQTAPAHHRDPCRQAGRRRGGAGPRSACLKRPM
CANQQGGGVRGRCPHLTAPLPKQAAEAGWGQRQYCFTHHAWRCAAGGAGAGGGESGGASQAPCPLPPQWLRRQDSEAFWGPGVATPTLGA
GGAWRVPITAGSSLRRGPGPGLFGHLDARAVLFAFRGDGQVFRGILLCSSLRGGSDLLVAVNHLCHEPYGQHHNEHIHHDLRHDGCHVSV
GFVHYLNVDLLDDAGVVLVVFEEEQAVDVALVVARVVVGDIGDEDRQILQVFGAPAAIPHHAALEALILLQLQHLILIAQDLDKLLSALL

--------------------------------------------------------------
>68084_68084_11_PPP2R5C-SCN1B_PPP2R5C_chr14_102276373_ENST00000556946_SCN1B_chr19_35523432_ENST00000415950_length(transcript)=1141nt_BP=202nt
AGTTCCCTCCAGCTGCAGAGAGCTTCAGTTTGTCTTTTTTTTTTTAAACTAAAATGGAGGCTGGTTTCTTGCCTTAAGGAGCCCATTGCC
TTTCCCGCTGAAGTCTAGATGTTGACATGTAATAAAGCGGGCAGCAGGATGGTGGTGGATGCGGCCAACTCCAATGGGCCTTTCCAGCCC
GTGGTCCTTCTCCATATTCGAGTGTCCTCAGCCTGCGGGGGCTGCGTGGAGGTGGACTCGGAGACCGAGGCCGTGTATGGGATGACCTTC
AAAATTCTTTGCATCTCCTGCAAGCGCCGCAGCGAGACCAACGCTGAGACCTTCACCGAGTGGACCTTCCGCCAGAAGGGCACTGAGGAG
TTTGTCAAGATCCTGCGCTATGAGAATGAGGTGTTGCAGCTGGAGGAGGATGAGCGCTTCGAGGGCCGCGTGGTGTGGAATGGCAGCCGG
GGCACCAAAGACCTGCAGGATCTGTCTATCTTCATCACCAATGTCACCTACAACCACTCGGGCGACTACGAGTGCCACGTCTACCGCCTG
CTCTTCTTCGAAAACTACGAGCACAACACCAGCGTCGTCAAGAAGATCCACATTGAGGTAGTGGACAAAGGTGAGTCGGGTGCTGCCTGC
CCCTTTACCGTCACCCACCGGAGAGCCAGATGGAGGGACAGATGGCAGGCAGTGGACAGGACAGGCTGGCTCTGTGCCTGGCCAGCCAAC
CGCCCACAGCAGCGGGCTGAGGGGGAGGGGAGCAGCCCCTCCTGCCCACTCCAGCTCTGGCCTCTGTTTCTCTCCAGCCCACGGAGAGGT
CAAAGCATGCCTGTCCCCCACAGACGCTCCGGGTACAGAACCCAGCTCTGTCACCTGTGCTGTATGACCTCTGGCAGGTGCCTTCTGTCT
CTGAGCCAAAGGGTTGTCCTGGGCTTGCCCGGGATAATAATCCGATGTGTTTCTCGGGGTGTGGTTTGAGCCATTCTTCCATCATGGGGT
TCATGAGGATTGAGCAGCTGCAGGCACACGCCTGGCTTCCAGCAGAGCCTTGCAGGTGGTGGCGAGGGTGGCGGTTCTTACTGTTCGAGT

>68084_68084_11_PPP2R5C-SCN1B_PPP2R5C_chr14_102276373_ENST00000556946_SCN1B_chr19_35523432_ENST00000415950_length(amino acids)=286AA_BP=31
MLTCNKAGSRMVVDAANSNGPFQPVVLLHIRVSSACGGCVEVDSETEAVYGMTFKILCISCKRRSETNAETFTEWTFRQKGTEEFVKILR
YENEVLQLEEDERFEGRVVWNGSRGTKDLQDLSIFITNVTYNHSGDYECHVYRLLFFENYEHNTSVVKKIHIEVVDKGESGAACPFTVTH
RRARWRDRWQAVDRTGWLCAWPANRPQQRAEGEGSSPSCPLQLWPLFLSSPRRGQSMPVPHRRSGYRTQLCHLCCMTSGRCLLSLSQRVV

--------------------------------------------------------------
>68084_68084_12_PPP2R5C-SCN1B_PPP2R5C_chr14_102276373_ENST00000556946_SCN1B_chr19_35523432_ENST00000595652_length(transcript)=888nt_BP=202nt
AGTTCCCTCCAGCTGCAGAGAGCTTCAGTTTGTCTTTTTTTTTTTAAACTAAAATGGAGGCTGGTTTCTTGCCTTAAGGAGCCCATTGCC
TTTCCCGCTGAAGTCTAGATGTTGACATGTAATAAAGCGGGCAGCAGGATGGTGGTGGATGCGGCCAACTCCAATGGGCCTTTCCAGCCC
GTGGTCCTTCTCCATATTCGAGTGTCCTCAGCCTGCGGGGGCTGCGTGGAGGTGGACTCGGAGACCGAGGCCGTGTATGGGATGACCTTC
AAAATTCTTTGCATCTCCTGCAAGCGCCGCAGCGAGACCAACGCTGAGACCTTCACCGAGTGGACCTTCCGCCAGAAGGGCACTGAGGAG
TTTGTCAAGAAGATCCACATTGAGGTAGTGGACAAAGCCAACAGAGACATGGCATCCATCGTGTCTGAGATCATGATGTATGTGCTCATT
GTGGTGTTGACCATATGGCTCGTGGCAGAGATGATTTACTGCTACAAGAAGATCGCTGCCGCCACGGAGACTGCTGCACAGGAGAATGCC
TCGGAATACCTGGCCATCACCTCTGAAAGCAAAGAGAACTGCACGGGCGTCCAGGTGGCCGAATAGCCCTGGCCCTGGGCCCCGCCTCAA
GGAAGAGCCAGCCGTAATGGGGACTCTCCAGGCACCGCCTGCCCCCAGCGTGGGGGTGGCCACTCCTGGGCCCCAGAAAGCCTCAGAGTC
CTGCCGACGGAGCCACTGGGGTGGGAGGGGGCAGGGGGCTTGGCTCGCACCCCCACTTTCGCCTCCTCCAGCTCCTGCCCCGCCGGCCGC

>68084_68084_12_PPP2R5C-SCN1B_PPP2R5C_chr14_102276373_ENST00000556946_SCN1B_chr19_35523432_ENST00000595652_length(amino acids)=165AA_BP=31
MLTCNKAGSRMVVDAANSNGPFQPVVLLHIRVSSACGGCVEVDSETEAVYGMTFKILCISCKRRSETNAETFTEWTFRQKGTEEFVKKIH

--------------------------------------------------------------
>68084_68084_13_PPP2R5C-SCN1B_PPP2R5C_chr14_102276373_ENST00000557095_SCN1B_chr19_35523432_ENST00000262631_length(transcript)=1406nt_BP=132nt
GCCTTAAGGAGCCCATTGCCTTTCCCGCTGAAGTCTAGATGTTGACATGTAATAAAGCGGGCAGCAGGATGGTGGTGGATGCGGCCAACT
CCAATGGGCCTTTCCAGCCCGTGGTCCTTCTCCATATTCGAGTGTCCTCAGCCTGCGGGGGCTGCGTGGAGGTGGACTCGGAGACCGAGG
CCGTGTATGGGATGACCTTCAAAATTCTTTGCATCTCCTGCAAGCGCCGCAGCGAGACCAACGCTGAGACCTTCACCGAGTGGACCTTCC
GCCAGAAGGGCACTGAGGAGTTTGTCAAGATCCTGCGCTATGAGAATGAGGTGTTGCAGCTGGAGGAGGATGAGCGCTTCGAGGGCCGCG
TGGTGTGGAATGGCAGCCGGGGCACCAAAGACCTGCAGGATCTGTCTATCTTCATCACCAATGTCACCTACAACCACTCGGGCGACTACG
AGTGCCACGTCTACCGCCTGCTCTTCTTCGAAAACTACGAGCACAACACCAGCGTCGTCAAGAAGATCCACATTGAGGTAGTGGACAAAG
CCAACAGAGACATGGCATCCATCGTGTCTGAGATCATGATGTATGTGCTCATTGTGGTGTTGACCATATGGCTCGTGGCAGAGATGATTT
ACTGCTACAAGAAGATCGCTGCCGCCACGGAGACTGCTGCACAGGAGAATGCCTCGGAATACCTGGCCATCACCTCTGAAAGCAAAGAGA
ACTGCACGGGCGTCCAGGTGGCCGAATAGCCCTGGCCCTGGGCCCCGCCTCAAGGAAGAGCCAGCCGTAATGGGGACTCTCCAGGCACCG
CCTGCCCCCAGCGTGGGGGTGGCCACTCCTGGGCCCCAGAAAGCCTCAGAGTCCTGCCGACGGAGCCACTGGGGTGGGAGGGGGCAGGGG
GCTTGGCTCGCACCCCCACTTTCGCCTCCTCCAGCTCCTGCCCCGCCGGCCGCGCACCGCCATGCATGATGGGTAAAGCAATACTGCCGC
TGCCCCCACCCTGCTTCTGCTGCCTGTTTGGGGAGGGGGGCGGTGAGGTGGGGGCAGCGGCCCCGCACCCCTCCTCCTTGCTGATTTGCA
CACATTGGCCGCTTCAGACACGCACTTCTGGGGCCAGCCCCTCCCCGCCTCCTCCCTGCCTGGCGGCAGGGGTCGCGATGATGGGCTGGA
GCAGTTTGGGGCAGGGGGTTCTGGGACCCACTCCGACTCCCCCTCCCCGGCATCATTTCCCCTCCCGCTTCCTCCGGCTGGACCTGGGGT
CCCCCCTCCCTGTAATGCACTCCTGCCCCGGCCCAACCTCGCCCTCTCTCACCAGCCTTGAACTGTGGCCACCTAGAAAGGGGCCCATTC

>68084_68084_13_PPP2R5C-SCN1B_PPP2R5C_chr14_102276373_ENST00000557095_SCN1B_chr19_35523432_ENST00000262631_length(amino acids)=404AA_BP=1
MNGPLSRWPQFKAGERGRGWAGAGVHYREGGPQVQPEEAGGEMMPGRGSRSGSQNPLPQTAPAHHRDPCRQAGRRRGGAGPRSACLKRPM
CANQQGGGVRGRCPHLTAPLPKQAAEAGWGQRQYCFTHHAWRCAAGGAGAGGGESGGASQAPCPLPPQWLRRQDSEAFWGPGVATPTLGA
GGAWRVPITAGSSLRRGPGPGLFGHLDARAVLFAFRGDGQVFRGILLCSSLRGGSDLLVAVNHLCHEPYGQHHNEHIHHDLRHDGCHVSV
GFVHYLNVDLLDDAGVVLVVFEEEQAVDVALVVARVVVGDIGDEDRQILQVFGAPAAIPHHAALEALILLQLQHLILIAQDLDKLLSALL

--------------------------------------------------------------
>68084_68084_14_PPP2R5C-SCN1B_PPP2R5C_chr14_102276373_ENST00000557095_SCN1B_chr19_35523432_ENST00000415950_length(transcript)=1071nt_BP=132nt
GCCTTAAGGAGCCCATTGCCTTTCCCGCTGAAGTCTAGATGTTGACATGTAATAAAGCGGGCAGCAGGATGGTGGTGGATGCGGCCAACT
CCAATGGGCCTTTCCAGCCCGTGGTCCTTCTCCATATTCGAGTGTCCTCAGCCTGCGGGGGCTGCGTGGAGGTGGACTCGGAGACCGAGG
CCGTGTATGGGATGACCTTCAAAATTCTTTGCATCTCCTGCAAGCGCCGCAGCGAGACCAACGCTGAGACCTTCACCGAGTGGACCTTCC
GCCAGAAGGGCACTGAGGAGTTTGTCAAGATCCTGCGCTATGAGAATGAGGTGTTGCAGCTGGAGGAGGATGAGCGCTTCGAGGGCCGCG
TGGTGTGGAATGGCAGCCGGGGCACCAAAGACCTGCAGGATCTGTCTATCTTCATCACCAATGTCACCTACAACCACTCGGGCGACTACG
AGTGCCACGTCTACCGCCTGCTCTTCTTCGAAAACTACGAGCACAACACCAGCGTCGTCAAGAAGATCCACATTGAGGTAGTGGACAAAG
GTGAGTCGGGTGCTGCCTGCCCCTTTACCGTCACCCACCGGAGAGCCAGATGGAGGGACAGATGGCAGGCAGTGGACAGGACAGGCTGGC
TCTGTGCCTGGCCAGCCAACCGCCCACAGCAGCGGGCTGAGGGGGAGGGGAGCAGCCCCTCCTGCCCACTCCAGCTCTGGCCTCTGTTTC
TCTCCAGCCCACGGAGAGGTCAAAGCATGCCTGTCCCCCACAGACGCTCCGGGTACAGAACCCAGCTCTGTCACCTGTGCTGTATGACCT
CTGGCAGGTGCCTTCTGTCTCTGAGCCAAAGGGTTGTCCTGGGCTTGCCCGGGATAATAATCCGATGTGTTTCTCGGGGTGTGGTTTGAG
CCATTCTTCCATCATGGGGTTCATGAGGATTGAGCAGCTGCAGGCACACGCCTGGCTTCCAGCAGAGCCTTGCAGGTGGTGGCGAGGGTG

>68084_68084_14_PPP2R5C-SCN1B_PPP2R5C_chr14_102276373_ENST00000557095_SCN1B_chr19_35523432_ENST00000415950_length(amino acids)=286AA_BP=31
MLTCNKAGSRMVVDAANSNGPFQPVVLLHIRVSSACGGCVEVDSETEAVYGMTFKILCISCKRRSETNAETFTEWTFRQKGTEEFVKILR
YENEVLQLEEDERFEGRVVWNGSRGTKDLQDLSIFITNVTYNHSGDYECHVYRLLFFENYEHNTSVVKKIHIEVVDKGESGAACPFTVTH
RRARWRDRWQAVDRTGWLCAWPANRPQQRAEGEGSSPSCPLQLWPLFLSSPRRGQSMPVPHRRSGYRTQLCHLCCMTSGRCLLSLSQRVV

--------------------------------------------------------------
>68084_68084_15_PPP2R5C-SCN1B_PPP2R5C_chr14_102276373_ENST00000557095_SCN1B_chr19_35523432_ENST00000595652_length(transcript)=818nt_BP=132nt
GCCTTAAGGAGCCCATTGCCTTTCCCGCTGAAGTCTAGATGTTGACATGTAATAAAGCGGGCAGCAGGATGGTGGTGGATGCGGCCAACT
CCAATGGGCCTTTCCAGCCCGTGGTCCTTCTCCATATTCGAGTGTCCTCAGCCTGCGGGGGCTGCGTGGAGGTGGACTCGGAGACCGAGG
CCGTGTATGGGATGACCTTCAAAATTCTTTGCATCTCCTGCAAGCGCCGCAGCGAGACCAACGCTGAGACCTTCACCGAGTGGACCTTCC
GCCAGAAGGGCACTGAGGAGTTTGTCAAGAAGATCCACATTGAGGTAGTGGACAAAGCCAACAGAGACATGGCATCCATCGTGTCTGAGA
TCATGATGTATGTGCTCATTGTGGTGTTGACCATATGGCTCGTGGCAGAGATGATTTACTGCTACAAGAAGATCGCTGCCGCCACGGAGA
CTGCTGCACAGGAGAATGCCTCGGAATACCTGGCCATCACCTCTGAAAGCAAAGAGAACTGCACGGGCGTCCAGGTGGCCGAATAGCCCT
GGCCCTGGGCCCCGCCTCAAGGAAGAGCCAGCCGTAATGGGGACTCTCCAGGCACCGCCTGCCCCCAGCGTGGGGGTGGCCACTCCTGGG
CCCCAGAAAGCCTCAGAGTCCTGCCGACGGAGCCACTGGGGTGGGAGGGGGCAGGGGGCTTGGCTCGCACCCCCACTTTCGCCTCCTCCA
GCTCCTGCCCCGCCGGCCGCGCACCGCCATGCATGATGGGTAAAGCAATACTGCCGCTGCCCCCACCCTGCTTCTGCTGCCTGTTTGGGG

>68084_68084_15_PPP2R5C-SCN1B_PPP2R5C_chr14_102276373_ENST00000557095_SCN1B_chr19_35523432_ENST00000595652_length(amino acids)=165AA_BP=31
MLTCNKAGSRMVVDAANSNGPFQPVVLLHIRVSSACGGCVEVDSETEAVYGMTFKILCISCKRRSETNAETFTEWTFRQKGTEEFVKKIH

--------------------------------------------------------------
>68084_68084_16_PPP2R5C-SCN1B_PPP2R5C_chr14_102276373_ENST00000557714_SCN1B_chr19_35523432_ENST00000262631_length(transcript)=1442nt_BP=168nt
TTTTTTTTTTTAAACTAAAATGGAGGCTGGTTTCTTGCCTTAAGGAGCCCATTGCCTTTCCCGCTGAAGTCTAGATGTTGACATGTAATA
AAGCGGGCAGCAGGATGGTGGTGGATGCGGCCAACTCCAATGGGCCTTTCCAGCCCGTGGTCCTTCTCCATATTCGAGTGTCCTCAGCCT
GCGGGGGCTGCGTGGAGGTGGACTCGGAGACCGAGGCCGTGTATGGGATGACCTTCAAAATTCTTTGCATCTCCTGCAAGCGCCGCAGCG
AGACCAACGCTGAGACCTTCACCGAGTGGACCTTCCGCCAGAAGGGCACTGAGGAGTTTGTCAAGATCCTGCGCTATGAGAATGAGGTGT
TGCAGCTGGAGGAGGATGAGCGCTTCGAGGGCCGCGTGGTGTGGAATGGCAGCCGGGGCACCAAAGACCTGCAGGATCTGTCTATCTTCA
TCACCAATGTCACCTACAACCACTCGGGCGACTACGAGTGCCACGTCTACCGCCTGCTCTTCTTCGAAAACTACGAGCACAACACCAGCG
TCGTCAAGAAGATCCACATTGAGGTAGTGGACAAAGCCAACAGAGACATGGCATCCATCGTGTCTGAGATCATGATGTATGTGCTCATTG
TGGTGTTGACCATATGGCTCGTGGCAGAGATGATTTACTGCTACAAGAAGATCGCTGCCGCCACGGAGACTGCTGCACAGGAGAATGCCT
CGGAATACCTGGCCATCACCTCTGAAAGCAAAGAGAACTGCACGGGCGTCCAGGTGGCCGAATAGCCCTGGCCCTGGGCCCCGCCTCAAG
GAAGAGCCAGCCGTAATGGGGACTCTCCAGGCACCGCCTGCCCCCAGCGTGGGGGTGGCCACTCCTGGGCCCCAGAAAGCCTCAGAGTCC
TGCCGACGGAGCCACTGGGGTGGGAGGGGGCAGGGGGCTTGGCTCGCACCCCCACTTTCGCCTCCTCCAGCTCCTGCCCCGCCGGCCGCG
CACCGCCATGCATGATGGGTAAAGCAATACTGCCGCTGCCCCCACCCTGCTTCTGCTGCCTGTTTGGGGAGGGGGGCGGTGAGGTGGGGG
CAGCGGCCCCGCACCCCTCCTCCTTGCTGATTTGCACACATTGGCCGCTTCAGACACGCACTTCTGGGGCCAGCCCCTCCCCGCCTCCTC
CCTGCCTGGCGGCAGGGGTCGCGATGATGGGCTGGAGCAGTTTGGGGCAGGGGGTTCTGGGACCCACTCCGACTCCCCCTCCCCGGCATC
ATTTCCCCTCCCGCTTCCTCCGGCTGGACCTGGGGTCCCCCCTCCCTGTAATGCACTCCTGCCCCGGCCCAACCTCGCCCTCTCTCACCA
GCCTTGAACTGTGGCCACCTAGAAAGGGGCCCATTCAGCCTCGTCTCTTTACAGAAGTAGTTTTGTTCATGAAATAAAGACTCTTGGACT

>68084_68084_16_PPP2R5C-SCN1B_PPP2R5C_chr14_102276373_ENST00000557714_SCN1B_chr19_35523432_ENST00000262631_length(amino acids)=404AA_BP=1
MNGPLSRWPQFKAGERGRGWAGAGVHYREGGPQVQPEEAGGEMMPGRGSRSGSQNPLPQTAPAHHRDPCRQAGRRRGGAGPRSACLKRPM
CANQQGGGVRGRCPHLTAPLPKQAAEAGWGQRQYCFTHHAWRCAAGGAGAGGGESGGASQAPCPLPPQWLRRQDSEAFWGPGVATPTLGA
GGAWRVPITAGSSLRRGPGPGLFGHLDARAVLFAFRGDGQVFRGILLCSSLRGGSDLLVAVNHLCHEPYGQHHNEHIHHDLRHDGCHVSV
GFVHYLNVDLLDDAGVVLVVFEEEQAVDVALVVARVVVGDIGDEDRQILQVFGAPAAIPHHAALEALILLQLQHLILIAQDLDKLLSALL

--------------------------------------------------------------
>68084_68084_17_PPP2R5C-SCN1B_PPP2R5C_chr14_102276373_ENST00000557714_SCN1B_chr19_35523432_ENST00000415950_length(transcript)=1107nt_BP=168nt
TTTTTTTTTTTAAACTAAAATGGAGGCTGGTTTCTTGCCTTAAGGAGCCCATTGCCTTTCCCGCTGAAGTCTAGATGTTGACATGTAATA
AAGCGGGCAGCAGGATGGTGGTGGATGCGGCCAACTCCAATGGGCCTTTCCAGCCCGTGGTCCTTCTCCATATTCGAGTGTCCTCAGCCT
GCGGGGGCTGCGTGGAGGTGGACTCGGAGACCGAGGCCGTGTATGGGATGACCTTCAAAATTCTTTGCATCTCCTGCAAGCGCCGCAGCG
AGACCAACGCTGAGACCTTCACCGAGTGGACCTTCCGCCAGAAGGGCACTGAGGAGTTTGTCAAGATCCTGCGCTATGAGAATGAGGTGT
TGCAGCTGGAGGAGGATGAGCGCTTCGAGGGCCGCGTGGTGTGGAATGGCAGCCGGGGCACCAAAGACCTGCAGGATCTGTCTATCTTCA
TCACCAATGTCACCTACAACCACTCGGGCGACTACGAGTGCCACGTCTACCGCCTGCTCTTCTTCGAAAACTACGAGCACAACACCAGCG
TCGTCAAGAAGATCCACATTGAGGTAGTGGACAAAGGTGAGTCGGGTGCTGCCTGCCCCTTTACCGTCACCCACCGGAGAGCCAGATGGA
GGGACAGATGGCAGGCAGTGGACAGGACAGGCTGGCTCTGTGCCTGGCCAGCCAACCGCCCACAGCAGCGGGCTGAGGGGGAGGGGAGCA
GCCCCTCCTGCCCACTCCAGCTCTGGCCTCTGTTTCTCTCCAGCCCACGGAGAGGTCAAAGCATGCCTGTCCCCCACAGACGCTCCGGGT
ACAGAACCCAGCTCTGTCACCTGTGCTGTATGACCTCTGGCAGGTGCCTTCTGTCTCTGAGCCAAAGGGTTGTCCTGGGCTTGCCCGGGA
TAATAATCCGATGTGTTTCTCGGGGTGTGGTTTGAGCCATTCTTCCATCATGGGGTTCATGAGGATTGAGCAGCTGCAGGCACACGCCTG
GCTTCCAGCAGAGCCTTGCAGGTGGTGGCGAGGGTGGCGGTTCTTACTGTTCGAGTAGCTCAGCCCTGCTGCCCTCTGTGGTGATGAGGC

>68084_68084_17_PPP2R5C-SCN1B_PPP2R5C_chr14_102276373_ENST00000557714_SCN1B_chr19_35523432_ENST00000415950_length(amino acids)=286AA_BP=31
MLTCNKAGSRMVVDAANSNGPFQPVVLLHIRVSSACGGCVEVDSETEAVYGMTFKILCISCKRRSETNAETFTEWTFRQKGTEEFVKILR
YENEVLQLEEDERFEGRVVWNGSRGTKDLQDLSIFITNVTYNHSGDYECHVYRLLFFENYEHNTSVVKKIHIEVVDKGESGAACPFTVTH
RRARWRDRWQAVDRTGWLCAWPANRPQQRAEGEGSSPSCPLQLWPLFLSSPRRGQSMPVPHRRSGYRTQLCHLCCMTSGRCLLSLSQRVV

--------------------------------------------------------------
>68084_68084_18_PPP2R5C-SCN1B_PPP2R5C_chr14_102276373_ENST00000557714_SCN1B_chr19_35523432_ENST00000595652_length(transcript)=854nt_BP=168nt
TTTTTTTTTTTAAACTAAAATGGAGGCTGGTTTCTTGCCTTAAGGAGCCCATTGCCTTTCCCGCTGAAGTCTAGATGTTGACATGTAATA
AAGCGGGCAGCAGGATGGTGGTGGATGCGGCCAACTCCAATGGGCCTTTCCAGCCCGTGGTCCTTCTCCATATTCGAGTGTCCTCAGCCT
GCGGGGGCTGCGTGGAGGTGGACTCGGAGACCGAGGCCGTGTATGGGATGACCTTCAAAATTCTTTGCATCTCCTGCAAGCGCCGCAGCG
AGACCAACGCTGAGACCTTCACCGAGTGGACCTTCCGCCAGAAGGGCACTGAGGAGTTTGTCAAGAAGATCCACATTGAGGTAGTGGACA
AAGCCAACAGAGACATGGCATCCATCGTGTCTGAGATCATGATGTATGTGCTCATTGTGGTGTTGACCATATGGCTCGTGGCAGAGATGA
TTTACTGCTACAAGAAGATCGCTGCCGCCACGGAGACTGCTGCACAGGAGAATGCCTCGGAATACCTGGCCATCACCTCTGAAAGCAAAG
AGAACTGCACGGGCGTCCAGGTGGCCGAATAGCCCTGGCCCTGGGCCCCGCCTCAAGGAAGAGCCAGCCGTAATGGGGACTCTCCAGGCA
CCGCCTGCCCCCAGCGTGGGGGTGGCCACTCCTGGGCCCCAGAAAGCCTCAGAGTCCTGCCGACGGAGCCACTGGGGTGGGAGGGGGCAG
GGGGCTTGGCTCGCACCCCCACTTTCGCCTCCTCCAGCTCCTGCCCCGCCGGCCGCGCACCGCCATGCATGATGGGTAAAGCAATACTGC

>68084_68084_18_PPP2R5C-SCN1B_PPP2R5C_chr14_102276373_ENST00000557714_SCN1B_chr19_35523432_ENST00000595652_length(amino acids)=165AA_BP=31
MLTCNKAGSRMVVDAANSNGPFQPVVLLHIRVSSACGGCVEVDSETEAVYGMTFKILCISCKRRSETNAETFTEWTFRQKGTEEFVKKIH

--------------------------------------------------------------

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Fusion Gene PPI Analysis for PPP2R5C-SCN1B


check button Go to ChiPPI (Chimeric Protein-Protein interactions) to see the chimeric PPI interaction in

ChiPPI page.


check button Protein-protein interactors with each fusion partner protein in wild-type (BIOGRID-3.4.160)
HgeneHgene's interactorsTgeneTgene's interactors


check button - Retained PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenStill interaction with


check button - Lost PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


check button - Retained PPIs, but lost function due to frame-shift fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


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Related Drugs for PPP2R5C-SCN1B


check button Drugs targeting genes involved in this fusion gene.
(DrugBank Version 5.1.8 2021-05-08)
PartnerGeneUniProtAccDrugBank IDDrug nameDrug activityDrug typeDrug status

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Related Diseases for PPP2R5C-SCN1B


check button Diseases associated with fusion partners.
(DisGeNet 4.0)
PartnerGeneDisease IDDisease name# pubmedsSource