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Center for Computational Systems Medicine
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Fusion Gene Summary

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Fusion Gene ORF analysis

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Fusion Genomic Features

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Fusion Protein Features

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Fusion Gene Sequence

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Fusion Gene PPI analysis

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Related Drugs

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Related Diseases

Fusion gene:PPP2R5D-ASCC3 (FusionGDB2 ID:68088)

Fusion Gene Summary for PPP2R5D-ASCC3

check button Fusion gene summary
Fusion gene informationFusion gene name: PPP2R5D-ASCC3
Fusion gene ID: 68088
HgeneTgene
Gene symbol

PPP2R5D

ASCC3

Gene ID

5528

10973

Gene nameprotein phosphatase 2 regulatory subunit B'deltaactivating signal cointegrator 1 complex subunit 3
SynonymsB56D|B56delta|MRD35ASC1p200|HELIC1|RNAH
Cytomap

6p21.1

6q16.3

Type of geneprotein-codingprotein-coding
Descriptionserine/threonine-protein phosphatase 2A 56 kDa regulatory subunit delta isoformPP2A, B subunit, B' delta isoformPP2A, B subunit, B56 delta isoformPP2A, B subunit, PR61 delta isoformPP2A, B subunit, R5 delta isoformSerine/threonine protein phosphataseactivating signal cointegrator 1 complex subunit 3ASC-1 complex subunit P200RNA helicase familyhelicase, ATP binding 1trip4 complex subunit p200
Modification date2020032720200313
UniProtAcc.

Q8N3C0

Ensembl transtripts involved in fusion geneENST00000394110, ENST00000472118, 
ENST00000485511, ENST00000461010, 
ENST00000369143, ENST00000369162, 
ENST00000522650, 
Fusion gene scores* DoF score6 X 3 X 5=9014 X 10 X 11=1540
# samples 718
** MAII scorelog2(7/90*10)=-0.362570079384708
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0		log2(18/1540*10)=-3.09686153925259
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0
Context

PubMed: PPP2R5D [Title/Abstract] AND ASCC3 [Title/Abstract] AND fusion [Title/Abstract]

Most frequent breakpointPPP2R5D(42957426)-ASCC3(101215221), # samples:3
Anticipated loss of major functional domain due to fusion event.
* DoF score (Degree of Frequency) = # partners X # break points X # cancer types
** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10)

check button Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez
PartnerGeneGO IDGO termPubMed ID
HgenePPP2R5D

GO:0006470

protein dephosphorylation

24157919

TgeneASCC3

GO:0006307

DNA dealkylation involved in DNA repair

22055184

TgeneASCC3

GO:0032508

DNA duplex unwinding

22055184


check buttonFusion gene breakpoints across PPP2R5D (5'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.
all structure

check buttonFusion gene breakpoints across ASCC3 (3'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.
all structure

check button Fusion gene information from two resources (ChiTars 5.0 and ChimerDB 4.0)
* All genome coordinats were lifted-over on hg19.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
SourceDiseaseSampleHgeneHchrHbpHstrandTgeneTchrTbpTstrand
ChimerDB4BRCATCGA-BH-A0BO-01APPP2R5Dchr6

42957426

-ASCC3chr6

101215221

-
ChimerDB4BRCATCGA-BH-A0BO-01APPP2R5Dchr6

42957426

+ASCC3chr6

101215221

-


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Fusion Gene ORF analysis for PPP2R5D-ASCC3

check button Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
ORFHenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrand
5CDS-intronENST00000394110ENST00000369143PPP2R5Dchr6

42957426

+ASCC3chr6

101215221

-
5CDS-intronENST00000472118ENST00000369143PPP2R5Dchr6

42957426

+ASCC3chr6

101215221

-
5CDS-intronENST00000485511ENST00000369143PPP2R5Dchr6

42957426

+ASCC3chr6

101215221

-
In-frameENST00000394110ENST00000369162PPP2R5Dchr6

42957426

+ASCC3chr6

101215221

-
In-frameENST00000394110ENST00000522650PPP2R5Dchr6

42957426

+ASCC3chr6

101215221

-
In-frameENST00000472118ENST00000369162PPP2R5Dchr6

42957426

+ASCC3chr6

101215221

-
In-frameENST00000472118ENST00000522650PPP2R5Dchr6

42957426

+ASCC3chr6

101215221

-
In-frameENST00000485511ENST00000369162PPP2R5Dchr6

42957426

+ASCC3chr6

101215221

-
In-frameENST00000485511ENST00000522650PPP2R5Dchr6

42957426

+ASCC3chr6

101215221

-
intron-3CDSENST00000461010ENST00000369162PPP2R5Dchr6

42957426

+ASCC3chr6

101215221

-
intron-3CDSENST00000461010ENST00000522650PPP2R5Dchr6

42957426

+ASCC3chr6

101215221

-
intron-intronENST00000461010ENST00000369143PPP2R5Dchr6

42957426

+ASCC3chr6

101215221

-

check buttonORFfinder result based on the fusion transcript sequence of in-frame fusion genes.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandSeq length
(transcript)		BP loci
(transcript)		Predicted start
(transcript)		Predicted stop
(transcript)		Seq length
(amino acids)
ENST00000485511PPP2R5Dchr642957426+ENST00000369162ASCC3chr6101215221-6690284554971830
ENST00000485511PPP2R5Dchr642957426+ENST00000522650ASCC3chr6101215221-137228451084359
ENST00000394110PPP2R5Dchr642957426+ENST00000369162ASCC3chr6101215221-663623012554431772
ENST00000394110PPP2R5Dchr642957426+ENST00000522650ASCC3chr6101215221-13182301251030301
ENST00000472118PPP2R5Dchr642957426+ENST00000369162ASCC3chr6101215221-663522912454421772
ENST00000472118PPP2R5Dchr642957426+ENST00000522650ASCC3chr6101215221-13172291241029301

check buttonDeepORF prediction of the coding potential based on the fusion transcript sequence of in-frame fusion genes. DeepORF is a coding potential classifier based on convolutional neural network by comparing the real Ribo-seq data. If the no-coding score < 0.5 and coding score > 0.5, then the in-frame fusion transcript is predicted as being likely translated.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandNo-coding scoreCoding score
ENST00000485511ENST00000369162PPP2R5Dchr642957426+ASCC3chr6101215221-0.0004524520.99954754
ENST00000485511ENST00000522650PPP2R5Dchr642957426+ASCC3chr6101215221-0.0006611130.9993389
ENST00000394110ENST00000369162PPP2R5Dchr642957426+ASCC3chr6101215221-0.0004159160.99958414
ENST00000394110ENST00000522650PPP2R5Dchr642957426+ASCC3chr6101215221-0.0005911690.99940884
ENST00000472118ENST00000369162PPP2R5Dchr642957426+ASCC3chr6101215221-0.0004166030.9995834
ENST00000472118ENST00000522650PPP2R5Dchr642957426+ASCC3chr6101215221-0.0005916140.99940836

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Fusion Genomic Features for PPP2R5D-ASCC3


check buttonFusionAI prediction of the potential fusion gene breakpoint based on the pre-mature RNA sequence context (+/- 5kb of individual partner genes, total 20kb length sequence). FusionAI is a fusion gene breakpoint classifier based on convolutional neural network by comparing the fusion positive and negative sequence context of ~ 20K fusion gene data. From here, we can have the relative potentency of the 20K genomic sequence how individual sequnce will be likely used as the gene fusion breakpoints.
HgeneHchrHbpHstrandTgeneTchrTbpTstrand1-pp (fusion gene breakpoint)

check buttonDistribution of 44 human genomic features loci across 20kb length fusion breakpoint regions. We integrated a total of 44 different types of human genomic feature loci information across five big categories including virus integration sites, repeats, structural variants, chromatin states, and gene expression regulation. More details are in help page.
genomic feature

check buttonDistribution of 44 human genomic features loci across 20kb length fusion breakpoint regions that are ovelapped with the top 1% feature importance score regions. More details are in help page.

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Fusion Protein Features for PPP2R5D-ASCC3


check button Four levels of functional features of fusion genes
Go to FGviewer search page for the most frequent breakpoint (https://ccsmweb.uth.edu/FGviewer/chr6:42957426/chr6:101215221)
- FGviewer provides the online visualization of the retention search of the protein functional features across DNA, RNA, protein, and pathological levels.
- How to search
1. Put your fusion gene symbol.
2. Press the tab key until there will be shown the breakpoint information filled.
4. Go down and press 'Search' tab twice.
4. Go down to have the hyperlink of the search result.
5. Click the hyperlink.
6. See the FGviewer result for your fusion gene.
FGviewer

check buttonMain function of each fusion partner protein. (from UniProt)
HgeneTgene
.ASCC3

Q8N3C0

FUNCTION: Transcriptional activator which is required for calcium-dependent dendritic growth and branching in cortical neurons. Recruits CREB-binding protein (CREBBP) to nuclear bodies. Component of the CREST-BRG1 complex, a multiprotein complex that regulates promoter activation by orchestrating a calcium-dependent release of a repressor complex and a recruitment of an activator complex. In resting neurons, transcription of the c-FOS promoter is inhibited by BRG1-dependent recruitment of a phospho-RB1-HDAC1 repressor complex. Upon calcium influx, RB1 is dephosphorylated by calcineurin, which leads to release of the repressor complex. At the same time, there is increased recruitment of CREBBP to the promoter by a CREST-dependent mechanism, which leads to transcriptional activation. The CREST-BRG1 complex also binds to the NR2B promoter, and activity-dependent induction of NR2B expression involves a release of HDAC1 and recruitment of CREBBP (By similarity). {ECO:0000250}.FUNCTION: 3'-5' DNA helicase involved in repair of alkylated DNA. Promotes DNA unwinding to generate single-stranded substrate needed for ALKBH3, enabling ALKBH3 to process alkylated N3-methylcytosine (3mC) within double-stranded regions (PubMed:22055184). Part of the ASC-1 complex that enhances NF-kappa-B, SRF and AP1 transactivation (PubMed:12077347). {ECO:0000269|PubMed:12077347, ECO:0000269|PubMed:22055184}.

check buttonRetention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at

download page


* Minus value of BPloci means that the break pointn is located before the CDS.
- In-frame and retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
HgenePPP2R5Dchr6:42957426chr6:101215221ENST00000394110+21637_3835571.0RepeatNote=1
HgenePPP2R5Dchr6:42957426chr6:101215221ENST00000485511+21637_3835603.0RepeatNote=1
TgeneASCC3chr6:42957426chr6:101215221ENST000003691430418_790112.0Coiled coilOntology_term=ECO:0000255
TgeneASCC3chr6:42957426chr6:101215221ENST0000036914304328_3560112.0Coiled coilOntology_term=ECO:0000255
TgeneASCC3chr6:42957426chr6:101215221ENST00000369143041336_15110112.0DomainHelicase ATP-binding 2
TgeneASCC3chr6:42957426chr6:101215221ENST00000369143041544_17390112.0DomainHelicase C-terminal 2
TgeneASCC3chr6:42957426chr6:101215221ENST00000369143041812_21760112.0DomainNote=SEC63 2
TgeneASCC3chr6:42957426chr6:101215221ENST0000036914304486_6690112.0DomainHelicase ATP-binding 1
TgeneASCC3chr6:42957426chr6:101215221ENST0000036914304728_9140112.0DomainHelicase C-terminal 1
TgeneASCC3chr6:42957426chr6:101215221ENST0000036914304978_12870112.0DomainNote=SEC63 1
TgeneASCC3chr6:42957426chr6:101215221ENST000003691627421336_15114652203.0DomainHelicase ATP-binding 2
TgeneASCC3chr6:42957426chr6:101215221ENST000003691627421544_17394652203.0DomainHelicase C-terminal 2
TgeneASCC3chr6:42957426chr6:101215221ENST000003691627421812_21764652203.0DomainNote=SEC63 2
TgeneASCC3chr6:42957426chr6:101215221ENST00000369162742486_6694652203.0DomainHelicase ATP-binding 1
TgeneASCC3chr6:42957426chr6:101215221ENST00000369162742728_9144652203.0DomainHelicase C-terminal 1
TgeneASCC3chr6:42957426chr6:101215221ENST00000369162742978_12874652203.0DomainNote=SEC63 1
TgeneASCC3chr6:42957426chr6:101215221ENST000005226507131336_1511465732.0DomainHelicase ATP-binding 2
TgeneASCC3chr6:42957426chr6:101215221ENST000005226507131544_1739465732.0DomainHelicase C-terminal 2
TgeneASCC3chr6:42957426chr6:101215221ENST000005226507131812_2176465732.0DomainNote=SEC63 2
TgeneASCC3chr6:42957426chr6:101215221ENST00000522650713486_669465732.0DomainHelicase ATP-binding 1
TgeneASCC3chr6:42957426chr6:101215221ENST00000522650713728_914465732.0DomainHelicase C-terminal 1
TgeneASCC3chr6:42957426chr6:101215221ENST00000522650713978_1287465732.0DomainNote=SEC63 1
TgeneASCC3chr6:42957426chr6:101215221ENST00000369143041453_14560112.0MotifNote=DEIH box
TgeneASCC3chr6:42957426chr6:101215221ENST0000036914304611_6140112.0MotifNote=DEVH box
TgeneASCC3chr6:42957426chr6:101215221ENST000003691627421453_14564652203.0MotifNote=DEIH box
TgeneASCC3chr6:42957426chr6:101215221ENST00000369162742611_6144652203.0MotifNote=DEVH box
TgeneASCC3chr6:42957426chr6:101215221ENST000005226507131453_1456465732.0MotifNote=DEIH box
TgeneASCC3chr6:42957426chr6:101215221ENST00000522650713611_614465732.0MotifNote=DEVH box
TgeneASCC3chr6:42957426chr6:101215221ENST00000369143041349_13560112.0Nucleotide bindingATP
TgeneASCC3chr6:42957426chr6:101215221ENST0000036914304499_5060112.0Nucleotide bindingATP
TgeneASCC3chr6:42957426chr6:101215221ENST000003691627421349_13564652203.0Nucleotide bindingATP
TgeneASCC3chr6:42957426chr6:101215221ENST00000369162742499_5064652203.0Nucleotide bindingATP
TgeneASCC3chr6:42957426chr6:101215221ENST000005226507131349_1356465732.0Nucleotide bindingATP
TgeneASCC3chr6:42957426chr6:101215221ENST00000522650713499_506465732.0Nucleotide bindingATP

- In-frame and not-retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
HgenePPP2R5Dchr6:42957426chr6:101215221ENST00000394110+216523_53035571.0MotifSH3-binding%3B class I
HgenePPP2R5Dchr6:42957426chr6:101215221ENST00000394110+216548_56535571.0MotifNuclear localization signal
HgenePPP2R5Dchr6:42957426chr6:101215221ENST00000461010+114523_5300497.0MotifSH3-binding%3B class I
HgenePPP2R5Dchr6:42957426chr6:101215221ENST00000461010+114548_5650497.0MotifNuclear localization signal
HgenePPP2R5Dchr6:42957426chr6:101215221ENST00000485511+216523_53035603.0MotifSH3-binding%3B class I
HgenePPP2R5Dchr6:42957426chr6:101215221ENST00000485511+216548_56535603.0MotifNuclear localization signal
HgenePPP2R5Dchr6:42957426chr6:101215221ENST00000394110+21637_5235571.0RegionNote=8 X 2 AA approximate tandem repeats of Q-P
HgenePPP2R5Dchr6:42957426chr6:101215221ENST00000461010+11437_520497.0RegionNote=8 X 2 AA approximate tandem repeats of Q-P
HgenePPP2R5Dchr6:42957426chr6:101215221ENST00000485511+21637_5235603.0RegionNote=8 X 2 AA approximate tandem repeats of Q-P
HgenePPP2R5Dchr6:42957426chr6:101215221ENST00000394110+21639_4035571.0RepeatNote=2
HgenePPP2R5Dchr6:42957426chr6:101215221ENST00000394110+21641_4235571.0RepeatNote=3
HgenePPP2R5Dchr6:42957426chr6:101215221ENST00000394110+21643_4435571.0RepeatNote=4
HgenePPP2R5Dchr6:42957426chr6:101215221ENST00000394110+21645_4635571.0RepeatNote=5
HgenePPP2R5Dchr6:42957426chr6:101215221ENST00000394110+21647_4835571.0RepeatNote=6%3B approximate
HgenePPP2R5Dchr6:42957426chr6:101215221ENST00000394110+21649_5035571.0RepeatNote=7%3B approximate
HgenePPP2R5Dchr6:42957426chr6:101215221ENST00000394110+21651_5235571.0RepeatNote=8
HgenePPP2R5Dchr6:42957426chr6:101215221ENST00000461010+11437_380497.0RepeatNote=1
HgenePPP2R5Dchr6:42957426chr6:101215221ENST00000461010+11439_400497.0RepeatNote=2
HgenePPP2R5Dchr6:42957426chr6:101215221ENST00000461010+11441_420497.0RepeatNote=3
HgenePPP2R5Dchr6:42957426chr6:101215221ENST00000461010+11443_440497.0RepeatNote=4
HgenePPP2R5Dchr6:42957426chr6:101215221ENST00000461010+11445_460497.0RepeatNote=5
HgenePPP2R5Dchr6:42957426chr6:101215221ENST00000461010+11447_480497.0RepeatNote=6%3B approximate
HgenePPP2R5Dchr6:42957426chr6:101215221ENST00000461010+11449_500497.0RepeatNote=7%3B approximate
HgenePPP2R5Dchr6:42957426chr6:101215221ENST00000461010+11451_520497.0RepeatNote=8
HgenePPP2R5Dchr6:42957426chr6:101215221ENST00000485511+21639_4035603.0RepeatNote=2
HgenePPP2R5Dchr6:42957426chr6:101215221ENST00000485511+21641_4235603.0RepeatNote=3
HgenePPP2R5Dchr6:42957426chr6:101215221ENST00000485511+21643_4435603.0RepeatNote=4
HgenePPP2R5Dchr6:42957426chr6:101215221ENST00000485511+21645_4635603.0RepeatNote=5
HgenePPP2R5Dchr6:42957426chr6:101215221ENST00000485511+21647_4835603.0RepeatNote=6%3B approximate
HgenePPP2R5Dchr6:42957426chr6:101215221ENST00000485511+21649_5035603.0RepeatNote=7%3B approximate
HgenePPP2R5Dchr6:42957426chr6:101215221ENST00000485511+21651_5235603.0RepeatNote=8
TgeneASCC3chr6:42957426chr6:101215221ENST0000036916274218_794652203.0Coiled coilOntology_term=ECO:0000255
TgeneASCC3chr6:42957426chr6:101215221ENST00000369162742328_3564652203.0Coiled coilOntology_term=ECO:0000255
TgeneASCC3chr6:42957426chr6:101215221ENST0000052265071318_79465732.0Coiled coilOntology_term=ECO:0000255
TgeneASCC3chr6:42957426chr6:101215221ENST00000522650713328_356465732.0Coiled coilOntology_term=ECO:0000255


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Fusion Gene Sequence for PPP2R5D-ASCC3


check button For in-frame fusion transcripts, we provide the fusion transcript sequences and fusion amino acid sequences. To have fusion amino acid sequence, we ran ORFfinder and chose the longest ORF among the all predicted ones.
>68088_68088_1_PPP2R5D-ASCC3_PPP2R5D_chr6_42957426_ENST00000394110_ASCC3_chr6_101215221_ENST00000369162_length(transcript)=6636nt_BP=230nt
CACCGCTCGACCCGGGCGCAGCGCGCAGGCGGTGGCGAAGAGACGCCGAGCGGGCCGAGTGCGGCCGAGCAAAGCCGGAGCCGGAGCGGG
GCCGCAGGAGACGGGCCGGGTCCGGACGGGCCGAGATGCCCTATAAACTGAAAAAGGAGAAGGAGCCCCCCAAGGTTGCCAAATGCACAG
CCAAGCCTAGCAGCTCGGGCAAGGATGGTGGAGGCGAGAACACTGAGGAGATCGGACAGCTGGCTTTTAAAGGAATGAAGAGACTCAATA
GAATCCAGTCAATAGTGTTTGAGACTGCCTACAACACCAATGAGAACATGCTGATTTGTGCCCCTACAGGAGCTGGAAAAACCAACATTG
CAATGCTGACAGTCTTGCATGAAATTCGCCAACATTTTCAACAAGGTGTTATCAAAAAGAATGAATTTAAGATTGTATATGTTGCTCCAA
TGAAAGCCTTGGCAGCTGAAATGACAGATTACTTCAGCAGACGTCTAGAGCCACTAGGCATCATTGTGAAAGAATTGACTGGTGACATGC
AGTTGTCCAAAAGTGAAATTTTACGAACTCAGATGCTTGTGACCACACCAGAAAAATGGGATGTAGTGACAAGAAAGAGTGTTGGGGATG
TAGCTCTTTCCCAGATTGTAAGGCTCCTTATTCTTGATGAAGTTCATTTGCTGCATGAAGATAGAGGACCAGTATTAGAAAGCATAGTTG
CCCGTACTTTACGGCAGGTGGAATCCACACAGAGTATGATAAGGATTCTCGGACTGTCTGCAACTTTACCTAACTACCTCGATGTTGCCA
CATTTTTACATGTTAATCCATACATTGGACTTTTCTTCTTTGATGGCCGTTTTCGACCAGTACCTCTTGGACAGACATTTTTGGGGATTA
AATGTGCAAATAAGATGCAGCAGTTGAATAACATGGATGAAGTATGTTATGAAAATGTTTTGAAGCAAGTAAAGGCTGGACACCAGGTGA
TGGTGTTTGTACATGCTCGAAATGCCACTGTAAGAACAGCTATGTCTCTAATAGAAAGAGCAAAAAATTGTGGCCATATTCCCTTCTTTT
TTCCTACCCAAGGACATGACTATGTACTTGCAGAAAAACAGGTACAAAGGTCGAGAAATAAGCAAGTACGAGAATTATTCCCAGATGGTT
TTAGTATTCATCATGCAGGAATGCTTCGGCAGGACAGAAATTTAGTTGAAAACTTGTTTTCTAATGGGCATATCAAAGTCCTAGTGTGTA
CAGCTACGTTAGCCTGGGGTGTCAATCTTCCCGCCCATGCTGTTATTATTAAGGGAACACAAATATATGCTGCAAAAAGAGGCTCCTTTG
TTGACCTTGGAATTTTAGATGTCATGCAGATATTTGGTCGAGCTGGACGACCACAATTTGACAAATTTGGGGAAGGAATAATTATAACAA
CGCATGATAAACTCAGCCATTACCTCACTTTGCTCACTCAACGAAACCCAATTGAGAGTCAGTTTCTGGAAAGCCTTGCAGATAACCTAA
ATGCAGAGATTGCTCTGGGAACAGTTACTAATGTGGAAGAAGCAGTGAAGTGGATAAGTTACACTTATCTTTATGTACGGATGAGAGCAA
ATCCATTAGCATATGGCATCAGTCACAAGGCTTATCAGATTGACCCAACATTAAGAAAGCATCGAGAACAGTTGGTCATTGAAGTTGGAC
GAAAACTAGACAAAGCTCAGATGATTCGTTTTGAGGAGCGAACTGGATATTTTTCCTCAACTGATTTGGGTAGAACTGCCAGCCATTACT
ATATTAAATACAACACCATTGAGACCTTTAATGAACTCTTTGATGCTCACAAAACAGAAGGTGATATCTTTGCCATAGTCTCCAAAGCTG
AAGAATTTGATCAAATTAAGGTCAGAGAAGAGGAAATAGAGGAGTTAGATACCTTATTAAGCAATTTTTGTGAACTCTCCACTCCTGGAG
GTGTAGAGAATAGTTATGGGAAAATAAACATCTTACTTCAAACTTATATCAGCCGAGGAGAAATGGACAGTTTCTCCCTTATATCAGATT
CTGCATATGTTGCACAGAATGCAGCTAGAATTGTCCGTGCTCTTTTTGAAATTGCTCTGAGGAAACGTTGGCCTACCATGACCTACAGGC
TCCTGAATCTTAGTAAAGTCATTGACAAGAGGCTTTGGGGTTGGGCTAGCCCTTTGAGACAATTTTCAATCCTACCACCACACATCCTAA
CAAGATTAGAAGAAAAAAAGCTTACTGTGGATAAGCTGAAAGACATGAGGAAAGATGAAATAGGTCACATTTTACATCATGTGAATATTG
GACTGAAGGTCAAACAATGTGTTCATCAGATTCCTTCTGTTATGATGGAAGCATCCATTCAGCCTATCACAAGGACTGTCCTCCGAGTGA
CACTCAGCATCTATGCTGATTTCACTTGGAATGATCAGGTACATGGGACAGTAGGAGAACCTTGGTGGATTTGGGTAGAAGATCCTACAA
ATGATCATATTTATCATTCAGAGTATTTTCTAGCTCTAAAAAAACAAGTCATTAGTAAAGAAGCCCAACTACTGGTATTTACAATCCCTA
TTTTTGAGCCTTTGCCTTCCCAATACTACATCCGAGCAGTGTCTGATAGATGGTTGGGTGCTGAGGCAGTATGTATTATCAACTTTCAAC
ATCTAATTCTACCAGAGAGACATCCTCCTCATACAGAATTACTGGATCTTCAGCCTTTACCAATCACAGCTTTGGGATGTAAAGCATATG
AAGCCCTGTACAACTTCAGCCACTTTAACCCTGTACAGACACAAATATTTCATACATTGTATCACACGGATTGTAATGTCCTACTTGGAG
CACCTACTGGATCGGGAAAGACTGTTGCAGCTGAATTAGCCATTTTCAGAGTCTTCAACAAATACCCTACTTCAAAGGCGGTATATATTG
CACCCCTAAAAGCCCTAGTACGTGAAAGAATGGATGATTGGAAAGTTAGAATAGAAGAAAAACTTGGTAAAAAAGTTATTGAACTAACAG
GGGATGTGACTCCTGATATGAAATCCATTGCCAAGGCTGACCTTATCGTCACTACGCCAGAGAAGTGGGATGGAGTCAGCAGAAGCTGGC
AAAATAGGAACTATGTTCAGCAAGTCACTATTCTCATCATAGATGAGATCCATCTGCTTGGGGAGGAAAGAGGCCCTGTTCTAGAGGTCA
TTGTATCTCGAACAAATTTTATCTCATCACACACAGAAAAGCCTGTTAGAATAGTTGGACTATCTACTGCATTAGCTAATGCCAGAGACC
TTGCTGATTGGCTCAATATTAAGCAGATGGGCTTGTTTAACTTCCGACCATCAGTACGCCCAGTTCCACTGGAAGTTCACATTCAAGGCT
TTCCAGGTCAACATTACTGTCCTCGTATGGCTAGTATGAACAAGCCTGCATTTCAGGCAATTAGAAGCCATTCTCCAGCCAAACCTGTTT
TGATATTTGTCTCATCAAGACGTCAAACTCGTCTTACTGCTTTGGAATTGATCGCCTTCCTGGCTACTGAAGAAGATCCAAAGCAGTGGT
TAAACATGGATGAAAGAGAGATGGAGAACATCATTGCAACAGTAAGAGATTCCAACCTCAAGCTGACCCTTGCTTTCGGGATAGGAATGC
ATCATGCTGGACTACATGAGAGGGACCGAAAAACAGTAGAGGAACTATTTGTAAACTGTAAAGTTCAGGTTCTTATTGCTACAAGCACAT
TAGCCTGGGGTGTAAACTTTCCAGCTCATTTAGTAATTATTAAGGGAACAGAATACTATGATGGAAAAACAAGACGTTATGTGGATTTTC
CCATTACAGATGTCCTCCAGATGATGGGGCGTGCTGGGAGGCCGCAGTTCGATGACCAAGGCAAAGCTGTAATTCTAGTTCATGACATAA
AGAAAGACTTTTATAAAAAATTTCTTTATGAACCTTTCCCAGTAGAATCAAGTTTATTAGGAGTGCTCTCTGACCACTTAAATGCAGAGA
TTGCTGGTGGTACAATTACATCTAAGCAAGATGCATTGGATTATATCACCTGGACTTACTTTTTCCGACGTCTTATCATGAATCCCAGCT
ATTACAATTTGGGTGATGTGAGCCATGATTCTGTGAACAAGTTTCTGTCCCATCTGATTGAGAAGTCCCTGATTGAATTGGAACTTTCCT
ACTGTATTGAAATTGGAGAGGATAATCGCAGCATTGAACCTCTAACTTATGGCCGAATTGCCTCCTATTACTATTTGAAGCATCAAACAG
TTAAAATGTTCAAGGACCGCTTGAAGCCTGAATGCAGTACTGAAGAACTGCTTTCAATTCTAAGTGATGCAGAAGAATATACAGATTTGC
CAGTGAGACACAATGAAGATCATATGAATAGTGAACTGGCAAAATGTCTTCCCATTGAATCAAATCCTCATTCATTTGACAGCCCTCACA
CCAAAGCACATCTCCTGCTACAGGCACATCTCAGCCGAGCCATGCTACCCTGCCCAGATTATGACACTGATACCAAAACAGTCTTGGACC
AAGCTCTCAGAGTATGTCAGGCAATGCTGGACGTGGCTGCAAACCAGGGCTGGCTGGTGACTGTCCTGAATATCACCAACCTGATTCAGA
TGGTGATCCAGGGTCGGTGGTTAAAGGACTCTTCTCTTCTTACACTACCAAACATAGAAAACCATCATCTTCACCTTTTCAAGAAATGGA
AGCCGATTATGAAGGGCCCACATGCTAGGGGTCGGACCTCCATCGAGTCCCTTCCTGAACTGATCCATGCCTGTGGAGGGAAAGACCATG
TATTTAGCTCCATGGTAGAAAGTGAGCTACATGCTGCAAAAACGAAACAGGCATGGAATTTCTTATCTCACTTGCCAGTGATAAATGTTG
GCATAAGTGTTAAAGGCTCGTGGGATGACTTAGTTGAAGGACATAATGAACTCTCTGTCTCAACTCTGACTGCAGACAAACGAGATGACA
ACAAATGGATCAAATTGCATGCTGACCAAGAGTATGTGCTTCAAGTGAGCTTGCAGAGAGTCCACTTTGGGTTCCACAAGGGAAAGCCAG
AGAGCTGTGCAGTTACTCCTCGATTTCCCAAATCAAAAGACGAAGGATGGTTTTTGATATTAGGAGAAGTGGATAAGAGAGAACTTATTG
CTTTGAAAAGAGTAGGATATATTCGAAATCATCATGTTGCTTCCCTTTCTTTTTATACCCCTGAAATACCTGGAAGGTATATCTACACAT
TATATTTCATGAGTGACTGCTACCTTGGCCTGGACCAGCAGTATGACATCTATCTCAACGTTACACAAGCGAGTCTTTCTGCACAGGTCA
ACACCAAGGTCTCTGATTCCCTGACTGACCTGGCATTAAAGTAACTTGACCTGAACAATCCATTTGAAAGGAGTGGCTAAGAATTCTCTC
TGTTCAGTCATCTAGACAAATCGAATTACTTGATGTTTGCCTTGAAAGAATCAACTTCTAACCTCAACCATCCAGGAAATTGACAGTGGC
TGCAGTATTGACTCCAGTGACATAAAGTTAACCACAGTGGCCTTTTAACAAATGTTGCCTTTTATAATGTTATCTTTATGAGTTTCTTGA
TATGTAAGATGAAAAAGCATTTAGAATAATCTTTTAATTTGTGTATATTTGGGATGATATTTAGGAGCTATCAATCAAATTTTACATCTC
ACAATGTACTGTTTACATGGATATTGGCTGCTTTTTTTAAGGAAAACCACATTGAGATGTGACAAGTGTTAGGACTTGTCACAGATTTCT
AACTCTGCCGCATAAACTATAAATCTGTAAGGTGGTACACAGCGTGTCTTGTTAGCAAAATTTATACTTTGATATGATCACATGTAGAAG
TAGCTTCAAGAATTTCTTGTAGTCATAAATGTTTAATAATATATGATGTAAAATTATATTATGGAGCCTAATGATGATAACAAAGAAAAC
AATATACTGATCTTAGAAAATGTAGACATGGTTAACTGGGAAATAAAATATAGAGTGGCACTTCAAGACAAGCTGACTCAATGTTTTCTT
CTGCTTCCTTTAAATAATATCCCCTTACTCATCTGTTCTTCTTTTCTTTCCCTTCTACTTCAAGGCTTTATTTCTATTATCTTTCTGACA
TATTTATTTACAGAAGTAGAGAAGTATAATCTAATTCATGTTGTAGCACTTACAGATCATATAGTACAATTATTTGTCTTTATGCTCTCC
AGGAAAAATCTGAGACAGAAAATTTTTCACCCCTATGGATAGGTTTTCACCTGTAATAAAGAAAATTTCTCTATGTCCAAACAAATTCCT
TCTTGAAAAATACTTTTTCAAACTAAAAACTTGTTAAAATTCAATGTTCATATAATATGCATTCTAGTGGAATGAAATTCTACCTTTGTG
AAATAATTTCAGTTTTCTTAGCCCTAAAATGAATTATTTTAAAACATTTTCCAATGTCATTGTTACAAATACTAGAATTTAAGTGTTTCT

>68088_68088_1_PPP2R5D-ASCC3_PPP2R5D_chr6_42957426_ENST00000394110_ASCC3_chr6_101215221_ENST00000369162_length(amino acids)=1772AA_BP=35
MPYKLKKEKEPPKVAKCTAKPSSSGKDGGGENTEEIGQLAFKGMKRLNRIQSIVFETAYNTNENMLICAPTGAGKTNIAMLTVLHEIRQH
FQQGVIKKNEFKIVYVAPMKALAAEMTDYFSRRLEPLGIIVKELTGDMQLSKSEILRTQMLVTTPEKWDVVTRKSVGDVALSQIVRLLIL
DEVHLLHEDRGPVLESIVARTLRQVESTQSMIRILGLSATLPNYLDVATFLHVNPYIGLFFFDGRFRPVPLGQTFLGIKCANKMQQLNNM
DEVCYENVLKQVKAGHQVMVFVHARNATVRTAMSLIERAKNCGHIPFFFPTQGHDYVLAEKQVQRSRNKQVRELFPDGFSIHHAGMLRQD
RNLVENLFSNGHIKVLVCTATLAWGVNLPAHAVIIKGTQIYAAKRGSFVDLGILDVMQIFGRAGRPQFDKFGEGIIITTHDKLSHYLTLL
TQRNPIESQFLESLADNLNAEIALGTVTNVEEAVKWISYTYLYVRMRANPLAYGISHKAYQIDPTLRKHREQLVIEVGRKLDKAQMIRFE
ERTGYFSSTDLGRTASHYYIKYNTIETFNELFDAHKTEGDIFAIVSKAEEFDQIKVREEEIEELDTLLSNFCELSTPGGVENSYGKINIL
LQTYISRGEMDSFSLISDSAYVAQNAARIVRALFEIALRKRWPTMTYRLLNLSKVIDKRLWGWASPLRQFSILPPHILTRLEEKKLTVDK
LKDMRKDEIGHILHHVNIGLKVKQCVHQIPSVMMEASIQPITRTVLRVTLSIYADFTWNDQVHGTVGEPWWIWVEDPTNDHIYHSEYFLA
LKKQVISKEAQLLVFTIPIFEPLPSQYYIRAVSDRWLGAEAVCIINFQHLILPERHPPHTELLDLQPLPITALGCKAYEALYNFSHFNPV
QTQIFHTLYHTDCNVLLGAPTGSGKTVAAELAIFRVFNKYPTSKAVYIAPLKALVRERMDDWKVRIEEKLGKKVIELTGDVTPDMKSIAK
ADLIVTTPEKWDGVSRSWQNRNYVQQVTILIIDEIHLLGEERGPVLEVIVSRTNFISSHTEKPVRIVGLSTALANARDLADWLNIKQMGL
FNFRPSVRPVPLEVHIQGFPGQHYCPRMASMNKPAFQAIRSHSPAKPVLIFVSSRRQTRLTALELIAFLATEEDPKQWLNMDEREMENII
ATVRDSNLKLTLAFGIGMHHAGLHERDRKTVEELFVNCKVQVLIATSTLAWGVNFPAHLVIIKGTEYYDGKTRRYVDFPITDVLQMMGRA
GRPQFDDQGKAVILVHDIKKDFYKKFLYEPFPVESSLLGVLSDHLNAEIAGGTITSKQDALDYITWTYFFRRLIMNPSYYNLGDVSHDSV
NKFLSHLIEKSLIELELSYCIEIGEDNRSIEPLTYGRIASYYYLKHQTVKMFKDRLKPECSTEELLSILSDAEEYTDLPVRHNEDHMNSE
LAKCLPIESNPHSFDSPHTKAHLLLQAHLSRAMLPCPDYDTDTKTVLDQALRVCQAMLDVAANQGWLVTVLNITNLIQMVIQGRWLKDSS
LLTLPNIENHHLHLFKKWKPIMKGPHARGRTSIESLPELIHACGGKDHVFSSMVESELHAAKTKQAWNFLSHLPVINVGISVKGSWDDLV
EGHNELSVSTLTADKRDDNKWIKLHADQEYVLQVSLQRVHFGFHKGKPESCAVTPRFPKSKDEGWFLILGEVDKRELIALKRVGYIRNHH

--------------------------------------------------------------
>68088_68088_2_PPP2R5D-ASCC3_PPP2R5D_chr6_42957426_ENST00000394110_ASCC3_chr6_101215221_ENST00000522650_length(transcript)=1318nt_BP=230nt
CACCGCTCGACCCGGGCGCAGCGCGCAGGCGGTGGCGAAGAGACGCCGAGCGGGCCGAGTGCGGCCGAGCAAAGCCGGAGCCGGAGCGGG
GCCGCAGGAGACGGGCCGGGTCCGGACGGGCCGAGATGCCCTATAAACTGAAAAAGGAGAAGGAGCCCCCCAAGGTTGCCAAATGCACAG
CCAAGCCTAGCAGCTCGGGCAAGGATGGTGGAGGCGAGAACACTGAGGAGATCGGACAGCTGGCTTTTAAAGGAATGAAGAGACTCAATA
GAATCCAGTCAATAGTGTTTGAGACTGCCTACAACACCAATGAGAACATGCTGATTTGTGCCCCTACAGGAGCTGGAAAAACCAACATTG
CAATGCTGACAGTCTTGCATGAAATTCGCCAACATTTTCAACAAGGTGTTATCAAAAAGAATGAATTTAAGATTGTATATGTTGCTCCAA
TGAAAGCCTTGGCAGCTGAAATGACAGATTACTTCAGCAGACGTCTAGAGCCACTAGGCATCATTGTGAAAGAATTGACTGGTGACATGC
AGTTGTCCAAAAGTGAAATTTTACGAACTCAGATGCTTGTGACCACACCAGAAAAATGGGATGTAGTGACAAGAAAGAGTGTTGGGGATG
TAGCTCTTTCCCAGATTGTAAGGCTCCTTATTCTTGATGAAGTTCATTTGCTGCATGAAGATAGAGGACCAGTATTAGAAAGCATAGTTG
CCCGTACTTTACGGCAGGTGGAATCCACACAGAGTATGATAAGGATTCTCGGACTGTCTGCAACTTTACCTAACTACCTCGATGTTGCCA
CATTTTTACATGTTAATCCATACATTGGACTTTTCTTCTTTGATGGCCGTTTTCGACCAGTACCTCTTGGACAGACATTTTTGGGGATTA
AATGTGCAAATAAGATGCAGCAGTTGAATAACATGGATGAAGTATGTTATGAAAATGTTTTGAAGCAAGTAAAGGCTGGACACCAGGTAC
ACTTATTTTATCTGCTTTTACACTTATTTATCTGCTTTTAGAGAGTGCTTAATGATAAAAATTATTAATATTTACGCTCTTCAGAAGAAA
ATTTTTCTTTAATTCTGAGGCAATGACTCAGAGGTTCTAATTCTTAATAACTGCTTTAGCCCAATGGGTAAGTCATAAAAATATTCATAG
ATATTATCATCCCAGTATTGATAGGTCGTGCTATTTTGTTTGCCATTTTTAATTTTAAATATTATATTCTTACTGTTTTCATGAAGCAAT

>68088_68088_2_PPP2R5D-ASCC3_PPP2R5D_chr6_42957426_ENST00000394110_ASCC3_chr6_101215221_ENST00000522650_length(amino acids)=301AA_BP=35
MPYKLKKEKEPPKVAKCTAKPSSSGKDGGGENTEEIGQLAFKGMKRLNRIQSIVFETAYNTNENMLICAPTGAGKTNIAMLTVLHEIRQH
FQQGVIKKNEFKIVYVAPMKALAAEMTDYFSRRLEPLGIIVKELTGDMQLSKSEILRTQMLVTTPEKWDVVTRKSVGDVALSQIVRLLIL
DEVHLLHEDRGPVLESIVARTLRQVESTQSMIRILGLSATLPNYLDVATFLHVNPYIGLFFFDGRFRPVPLGQTFLGIKCANKMQQLNNM

--------------------------------------------------------------
>68088_68088_3_PPP2R5D-ASCC3_PPP2R5D_chr6_42957426_ENST00000472118_ASCC3_chr6_101215221_ENST00000369162_length(transcript)=6635nt_BP=229nt
ACCGCTCGACCCGGGCGCAGCGCGCAGGCGGTGGCGAAGAGACGCCGAGCGGGCCGAGTGCGGCCGAGCAAAGCCGGAGCCGGAGCGGGG
CCGCAGGAGACGGGCCGGGTCCGGACGGGCCGAGATGCCCTATAAACTGAAAAAGGAGAAGGAGCCCCCCAAGGTTGCCAAATGCACAGC
CAAGCCTAGCAGCTCGGGCAAGGATGGTGGAGGCGAGAACACTGAGGAGATCGGACAGCTGGCTTTTAAAGGAATGAAGAGACTCAATAG
AATCCAGTCAATAGTGTTTGAGACTGCCTACAACACCAATGAGAACATGCTGATTTGTGCCCCTACAGGAGCTGGAAAAACCAACATTGC
AATGCTGACAGTCTTGCATGAAATTCGCCAACATTTTCAACAAGGTGTTATCAAAAAGAATGAATTTAAGATTGTATATGTTGCTCCAAT
GAAAGCCTTGGCAGCTGAAATGACAGATTACTTCAGCAGACGTCTAGAGCCACTAGGCATCATTGTGAAAGAATTGACTGGTGACATGCA
GTTGTCCAAAAGTGAAATTTTACGAACTCAGATGCTTGTGACCACACCAGAAAAATGGGATGTAGTGACAAGAAAGAGTGTTGGGGATGT
AGCTCTTTCCCAGATTGTAAGGCTCCTTATTCTTGATGAAGTTCATTTGCTGCATGAAGATAGAGGACCAGTATTAGAAAGCATAGTTGC
CCGTACTTTACGGCAGGTGGAATCCACACAGAGTATGATAAGGATTCTCGGACTGTCTGCAACTTTACCTAACTACCTCGATGTTGCCAC
ATTTTTACATGTTAATCCATACATTGGACTTTTCTTCTTTGATGGCCGTTTTCGACCAGTACCTCTTGGACAGACATTTTTGGGGATTAA
ATGTGCAAATAAGATGCAGCAGTTGAATAACATGGATGAAGTATGTTATGAAAATGTTTTGAAGCAAGTAAAGGCTGGACACCAGGTGAT
GGTGTTTGTACATGCTCGAAATGCCACTGTAAGAACAGCTATGTCTCTAATAGAAAGAGCAAAAAATTGTGGCCATATTCCCTTCTTTTT
TCCTACCCAAGGACATGACTATGTACTTGCAGAAAAACAGGTACAAAGGTCGAGAAATAAGCAAGTACGAGAATTATTCCCAGATGGTTT
TAGTATTCATCATGCAGGAATGCTTCGGCAGGACAGAAATTTAGTTGAAAACTTGTTTTCTAATGGGCATATCAAAGTCCTAGTGTGTAC
AGCTACGTTAGCCTGGGGTGTCAATCTTCCCGCCCATGCTGTTATTATTAAGGGAACACAAATATATGCTGCAAAAAGAGGCTCCTTTGT
TGACCTTGGAATTTTAGATGTCATGCAGATATTTGGTCGAGCTGGACGACCACAATTTGACAAATTTGGGGAAGGAATAATTATAACAAC
GCATGATAAACTCAGCCATTACCTCACTTTGCTCACTCAACGAAACCCAATTGAGAGTCAGTTTCTGGAAAGCCTTGCAGATAACCTAAA
TGCAGAGATTGCTCTGGGAACAGTTACTAATGTGGAAGAAGCAGTGAAGTGGATAAGTTACACTTATCTTTATGTACGGATGAGAGCAAA
TCCATTAGCATATGGCATCAGTCACAAGGCTTATCAGATTGACCCAACATTAAGAAAGCATCGAGAACAGTTGGTCATTGAAGTTGGACG
AAAACTAGACAAAGCTCAGATGATTCGTTTTGAGGAGCGAACTGGATATTTTTCCTCAACTGATTTGGGTAGAACTGCCAGCCATTACTA
TATTAAATACAACACCATTGAGACCTTTAATGAACTCTTTGATGCTCACAAAACAGAAGGTGATATCTTTGCCATAGTCTCCAAAGCTGA
AGAATTTGATCAAATTAAGGTCAGAGAAGAGGAAATAGAGGAGTTAGATACCTTATTAAGCAATTTTTGTGAACTCTCCACTCCTGGAGG
TGTAGAGAATAGTTATGGGAAAATAAACATCTTACTTCAAACTTATATCAGCCGAGGAGAAATGGACAGTTTCTCCCTTATATCAGATTC
TGCATATGTTGCACAGAATGCAGCTAGAATTGTCCGTGCTCTTTTTGAAATTGCTCTGAGGAAACGTTGGCCTACCATGACCTACAGGCT
CCTGAATCTTAGTAAAGTCATTGACAAGAGGCTTTGGGGTTGGGCTAGCCCTTTGAGACAATTTTCAATCCTACCACCACACATCCTAAC
AAGATTAGAAGAAAAAAAGCTTACTGTGGATAAGCTGAAAGACATGAGGAAAGATGAAATAGGTCACATTTTACATCATGTGAATATTGG
ACTGAAGGTCAAACAATGTGTTCATCAGATTCCTTCTGTTATGATGGAAGCATCCATTCAGCCTATCACAAGGACTGTCCTCCGAGTGAC
ACTCAGCATCTATGCTGATTTCACTTGGAATGATCAGGTACATGGGACAGTAGGAGAACCTTGGTGGATTTGGGTAGAAGATCCTACAAA
TGATCATATTTATCATTCAGAGTATTTTCTAGCTCTAAAAAAACAAGTCATTAGTAAAGAAGCCCAACTACTGGTATTTACAATCCCTAT
TTTTGAGCCTTTGCCTTCCCAATACTACATCCGAGCAGTGTCTGATAGATGGTTGGGTGCTGAGGCAGTATGTATTATCAACTTTCAACA
TCTAATTCTACCAGAGAGACATCCTCCTCATACAGAATTACTGGATCTTCAGCCTTTACCAATCACAGCTTTGGGATGTAAAGCATATGA
AGCCCTGTACAACTTCAGCCACTTTAACCCTGTACAGACACAAATATTTCATACATTGTATCACACGGATTGTAATGTCCTACTTGGAGC
ACCTACTGGATCGGGAAAGACTGTTGCAGCTGAATTAGCCATTTTCAGAGTCTTCAACAAATACCCTACTTCAAAGGCGGTATATATTGC
ACCCCTAAAAGCCCTAGTACGTGAAAGAATGGATGATTGGAAAGTTAGAATAGAAGAAAAACTTGGTAAAAAAGTTATTGAACTAACAGG
GGATGTGACTCCTGATATGAAATCCATTGCCAAGGCTGACCTTATCGTCACTACGCCAGAGAAGTGGGATGGAGTCAGCAGAAGCTGGCA
AAATAGGAACTATGTTCAGCAAGTCACTATTCTCATCATAGATGAGATCCATCTGCTTGGGGAGGAAAGAGGCCCTGTTCTAGAGGTCAT
TGTATCTCGAACAAATTTTATCTCATCACACACAGAAAAGCCTGTTAGAATAGTTGGACTATCTACTGCATTAGCTAATGCCAGAGACCT
TGCTGATTGGCTCAATATTAAGCAGATGGGCTTGTTTAACTTCCGACCATCAGTACGCCCAGTTCCACTGGAAGTTCACATTCAAGGCTT
TCCAGGTCAACATTACTGTCCTCGTATGGCTAGTATGAACAAGCCTGCATTTCAGGCAATTAGAAGCCATTCTCCAGCCAAACCTGTTTT
GATATTTGTCTCATCAAGACGTCAAACTCGTCTTACTGCTTTGGAATTGATCGCCTTCCTGGCTACTGAAGAAGATCCAAAGCAGTGGTT
AAACATGGATGAAAGAGAGATGGAGAACATCATTGCAACAGTAAGAGATTCCAACCTCAAGCTGACCCTTGCTTTCGGGATAGGAATGCA
TCATGCTGGACTACATGAGAGGGACCGAAAAACAGTAGAGGAACTATTTGTAAACTGTAAAGTTCAGGTTCTTATTGCTACAAGCACATT
AGCCTGGGGTGTAAACTTTCCAGCTCATTTAGTAATTATTAAGGGAACAGAATACTATGATGGAAAAACAAGACGTTATGTGGATTTTCC
CATTACAGATGTCCTCCAGATGATGGGGCGTGCTGGGAGGCCGCAGTTCGATGACCAAGGCAAAGCTGTAATTCTAGTTCATGACATAAA
GAAAGACTTTTATAAAAAATTTCTTTATGAACCTTTCCCAGTAGAATCAAGTTTATTAGGAGTGCTCTCTGACCACTTAAATGCAGAGAT
TGCTGGTGGTACAATTACATCTAAGCAAGATGCATTGGATTATATCACCTGGACTTACTTTTTCCGACGTCTTATCATGAATCCCAGCTA
TTACAATTTGGGTGATGTGAGCCATGATTCTGTGAACAAGTTTCTGTCCCATCTGATTGAGAAGTCCCTGATTGAATTGGAACTTTCCTA
CTGTATTGAAATTGGAGAGGATAATCGCAGCATTGAACCTCTAACTTATGGCCGAATTGCCTCCTATTACTATTTGAAGCATCAAACAGT
TAAAATGTTCAAGGACCGCTTGAAGCCTGAATGCAGTACTGAAGAACTGCTTTCAATTCTAAGTGATGCAGAAGAATATACAGATTTGCC
AGTGAGACACAATGAAGATCATATGAATAGTGAACTGGCAAAATGTCTTCCCATTGAATCAAATCCTCATTCATTTGACAGCCCTCACAC
CAAAGCACATCTCCTGCTACAGGCACATCTCAGCCGAGCCATGCTACCCTGCCCAGATTATGACACTGATACCAAAACAGTCTTGGACCA
AGCTCTCAGAGTATGTCAGGCAATGCTGGACGTGGCTGCAAACCAGGGCTGGCTGGTGACTGTCCTGAATATCACCAACCTGATTCAGAT
GGTGATCCAGGGTCGGTGGTTAAAGGACTCTTCTCTTCTTACACTACCAAACATAGAAAACCATCATCTTCACCTTTTCAAGAAATGGAA
GCCGATTATGAAGGGCCCACATGCTAGGGGTCGGACCTCCATCGAGTCCCTTCCTGAACTGATCCATGCCTGTGGAGGGAAAGACCATGT
ATTTAGCTCCATGGTAGAAAGTGAGCTACATGCTGCAAAAACGAAACAGGCATGGAATTTCTTATCTCACTTGCCAGTGATAAATGTTGG
CATAAGTGTTAAAGGCTCGTGGGATGACTTAGTTGAAGGACATAATGAACTCTCTGTCTCAACTCTGACTGCAGACAAACGAGATGACAA
CAAATGGATCAAATTGCATGCTGACCAAGAGTATGTGCTTCAAGTGAGCTTGCAGAGAGTCCACTTTGGGTTCCACAAGGGAAAGCCAGA
GAGCTGTGCAGTTACTCCTCGATTTCCCAAATCAAAAGACGAAGGATGGTTTTTGATATTAGGAGAAGTGGATAAGAGAGAACTTATTGC
TTTGAAAAGAGTAGGATATATTCGAAATCATCATGTTGCTTCCCTTTCTTTTTATACCCCTGAAATACCTGGAAGGTATATCTACACATT
ATATTTCATGAGTGACTGCTACCTTGGCCTGGACCAGCAGTATGACATCTATCTCAACGTTACACAAGCGAGTCTTTCTGCACAGGTCAA
CACCAAGGTCTCTGATTCCCTGACTGACCTGGCATTAAAGTAACTTGACCTGAACAATCCATTTGAAAGGAGTGGCTAAGAATTCTCTCT
GTTCAGTCATCTAGACAAATCGAATTACTTGATGTTTGCCTTGAAAGAATCAACTTCTAACCTCAACCATCCAGGAAATTGACAGTGGCT
GCAGTATTGACTCCAGTGACATAAAGTTAACCACAGTGGCCTTTTAACAAATGTTGCCTTTTATAATGTTATCTTTATGAGTTTCTTGAT
ATGTAAGATGAAAAAGCATTTAGAATAATCTTTTAATTTGTGTATATTTGGGATGATATTTAGGAGCTATCAATCAAATTTTACATCTCA
CAATGTACTGTTTACATGGATATTGGCTGCTTTTTTTAAGGAAAACCACATTGAGATGTGACAAGTGTTAGGACTTGTCACAGATTTCTA
ACTCTGCCGCATAAACTATAAATCTGTAAGGTGGTACACAGCGTGTCTTGTTAGCAAAATTTATACTTTGATATGATCACATGTAGAAGT
AGCTTCAAGAATTTCTTGTAGTCATAAATGTTTAATAATATATGATGTAAAATTATATTATGGAGCCTAATGATGATAACAAAGAAAACA
ATATACTGATCTTAGAAAATGTAGACATGGTTAACTGGGAAATAAAATATAGAGTGGCACTTCAAGACAAGCTGACTCAATGTTTTCTTC
TGCTTCCTTTAAATAATATCCCCTTACTCATCTGTTCTTCTTTTCTTTCCCTTCTACTTCAAGGCTTTATTTCTATTATCTTTCTGACAT
ATTTATTTACAGAAGTAGAGAAGTATAATCTAATTCATGTTGTAGCACTTACAGATCATATAGTACAATTATTTGTCTTTATGCTCTCCA
GGAAAAATCTGAGACAGAAAATTTTTCACCCCTATGGATAGGTTTTCACCTGTAATAAAGAAAATTTCTCTATGTCCAAACAAATTCCTT
CTTGAAAAATACTTTTTCAAACTAAAAACTTGTTAAAATTCAATGTTCATATAATATGCATTCTAGTGGAATGAAATTCTACCTTTGTGA
AATAATTTCAGTTTTCTTAGCCCTAAAATGAATTATTTTAAAACATTTTCCAATGTCATTGTTACAAATACTAGAATTTAAGTGTTTCTG

>68088_68088_3_PPP2R5D-ASCC3_PPP2R5D_chr6_42957426_ENST00000472118_ASCC3_chr6_101215221_ENST00000369162_length(amino acids)=1772AA_BP=35
MPYKLKKEKEPPKVAKCTAKPSSSGKDGGGENTEEIGQLAFKGMKRLNRIQSIVFETAYNTNENMLICAPTGAGKTNIAMLTVLHEIRQH
FQQGVIKKNEFKIVYVAPMKALAAEMTDYFSRRLEPLGIIVKELTGDMQLSKSEILRTQMLVTTPEKWDVVTRKSVGDVALSQIVRLLIL
DEVHLLHEDRGPVLESIVARTLRQVESTQSMIRILGLSATLPNYLDVATFLHVNPYIGLFFFDGRFRPVPLGQTFLGIKCANKMQQLNNM
DEVCYENVLKQVKAGHQVMVFVHARNATVRTAMSLIERAKNCGHIPFFFPTQGHDYVLAEKQVQRSRNKQVRELFPDGFSIHHAGMLRQD
RNLVENLFSNGHIKVLVCTATLAWGVNLPAHAVIIKGTQIYAAKRGSFVDLGILDVMQIFGRAGRPQFDKFGEGIIITTHDKLSHYLTLL
TQRNPIESQFLESLADNLNAEIALGTVTNVEEAVKWISYTYLYVRMRANPLAYGISHKAYQIDPTLRKHREQLVIEVGRKLDKAQMIRFE
ERTGYFSSTDLGRTASHYYIKYNTIETFNELFDAHKTEGDIFAIVSKAEEFDQIKVREEEIEELDTLLSNFCELSTPGGVENSYGKINIL
LQTYISRGEMDSFSLISDSAYVAQNAARIVRALFEIALRKRWPTMTYRLLNLSKVIDKRLWGWASPLRQFSILPPHILTRLEEKKLTVDK
LKDMRKDEIGHILHHVNIGLKVKQCVHQIPSVMMEASIQPITRTVLRVTLSIYADFTWNDQVHGTVGEPWWIWVEDPTNDHIYHSEYFLA
LKKQVISKEAQLLVFTIPIFEPLPSQYYIRAVSDRWLGAEAVCIINFQHLILPERHPPHTELLDLQPLPITALGCKAYEALYNFSHFNPV
QTQIFHTLYHTDCNVLLGAPTGSGKTVAAELAIFRVFNKYPTSKAVYIAPLKALVRERMDDWKVRIEEKLGKKVIELTGDVTPDMKSIAK
ADLIVTTPEKWDGVSRSWQNRNYVQQVTILIIDEIHLLGEERGPVLEVIVSRTNFISSHTEKPVRIVGLSTALANARDLADWLNIKQMGL
FNFRPSVRPVPLEVHIQGFPGQHYCPRMASMNKPAFQAIRSHSPAKPVLIFVSSRRQTRLTALELIAFLATEEDPKQWLNMDEREMENII
ATVRDSNLKLTLAFGIGMHHAGLHERDRKTVEELFVNCKVQVLIATSTLAWGVNFPAHLVIIKGTEYYDGKTRRYVDFPITDVLQMMGRA
GRPQFDDQGKAVILVHDIKKDFYKKFLYEPFPVESSLLGVLSDHLNAEIAGGTITSKQDALDYITWTYFFRRLIMNPSYYNLGDVSHDSV
NKFLSHLIEKSLIELELSYCIEIGEDNRSIEPLTYGRIASYYYLKHQTVKMFKDRLKPECSTEELLSILSDAEEYTDLPVRHNEDHMNSE
LAKCLPIESNPHSFDSPHTKAHLLLQAHLSRAMLPCPDYDTDTKTVLDQALRVCQAMLDVAANQGWLVTVLNITNLIQMVIQGRWLKDSS
LLTLPNIENHHLHLFKKWKPIMKGPHARGRTSIESLPELIHACGGKDHVFSSMVESELHAAKTKQAWNFLSHLPVINVGISVKGSWDDLV
EGHNELSVSTLTADKRDDNKWIKLHADQEYVLQVSLQRVHFGFHKGKPESCAVTPRFPKSKDEGWFLILGEVDKRELIALKRVGYIRNHH

--------------------------------------------------------------
>68088_68088_4_PPP2R5D-ASCC3_PPP2R5D_chr6_42957426_ENST00000472118_ASCC3_chr6_101215221_ENST00000522650_length(transcript)=1317nt_BP=229nt
ACCGCTCGACCCGGGCGCAGCGCGCAGGCGGTGGCGAAGAGACGCCGAGCGGGCCGAGTGCGGCCGAGCAAAGCCGGAGCCGGAGCGGGG
CCGCAGGAGACGGGCCGGGTCCGGACGGGCCGAGATGCCCTATAAACTGAAAAAGGAGAAGGAGCCCCCCAAGGTTGCCAAATGCACAGC
CAAGCCTAGCAGCTCGGGCAAGGATGGTGGAGGCGAGAACACTGAGGAGATCGGACAGCTGGCTTTTAAAGGAATGAAGAGACTCAATAG
AATCCAGTCAATAGTGTTTGAGACTGCCTACAACACCAATGAGAACATGCTGATTTGTGCCCCTACAGGAGCTGGAAAAACCAACATTGC
AATGCTGACAGTCTTGCATGAAATTCGCCAACATTTTCAACAAGGTGTTATCAAAAAGAATGAATTTAAGATTGTATATGTTGCTCCAAT
GAAAGCCTTGGCAGCTGAAATGACAGATTACTTCAGCAGACGTCTAGAGCCACTAGGCATCATTGTGAAAGAATTGACTGGTGACATGCA
GTTGTCCAAAAGTGAAATTTTACGAACTCAGATGCTTGTGACCACACCAGAAAAATGGGATGTAGTGACAAGAAAGAGTGTTGGGGATGT
AGCTCTTTCCCAGATTGTAAGGCTCCTTATTCTTGATGAAGTTCATTTGCTGCATGAAGATAGAGGACCAGTATTAGAAAGCATAGTTGC
CCGTACTTTACGGCAGGTGGAATCCACACAGAGTATGATAAGGATTCTCGGACTGTCTGCAACTTTACCTAACTACCTCGATGTTGCCAC
ATTTTTACATGTTAATCCATACATTGGACTTTTCTTCTTTGATGGCCGTTTTCGACCAGTACCTCTTGGACAGACATTTTTGGGGATTAA
ATGTGCAAATAAGATGCAGCAGTTGAATAACATGGATGAAGTATGTTATGAAAATGTTTTGAAGCAAGTAAAGGCTGGACACCAGGTACA
CTTATTTTATCTGCTTTTACACTTATTTATCTGCTTTTAGAGAGTGCTTAATGATAAAAATTATTAATATTTACGCTCTTCAGAAGAAAA
TTTTTCTTTAATTCTGAGGCAATGACTCAGAGGTTCTAATTCTTAATAACTGCTTTAGCCCAATGGGTAAGTCATAAAAATATTCATAGA
TATTATCATCCCAGTATTGATAGGTCGTGCTATTTTGTTTGCCATTTTTAATTTTAAATATTATATTCTTACTGTTTTCATGAAGCAATA

>68088_68088_4_PPP2R5D-ASCC3_PPP2R5D_chr6_42957426_ENST00000472118_ASCC3_chr6_101215221_ENST00000522650_length(amino acids)=301AA_BP=35
MPYKLKKEKEPPKVAKCTAKPSSSGKDGGGENTEEIGQLAFKGMKRLNRIQSIVFETAYNTNENMLICAPTGAGKTNIAMLTVLHEIRQH
FQQGVIKKNEFKIVYVAPMKALAAEMTDYFSRRLEPLGIIVKELTGDMQLSKSEILRTQMLVTTPEKWDVVTRKSVGDVALSQIVRLLIL
DEVHLLHEDRGPVLESIVARTLRQVESTQSMIRILGLSATLPNYLDVATFLHVNPYIGLFFFDGRFRPVPLGQTFLGIKCANKMQQLNNM

--------------------------------------------------------------
>68088_68088_5_PPP2R5D-ASCC3_PPP2R5D_chr6_42957426_ENST00000485511_ASCC3_chr6_101215221_ENST00000369162_length(transcript)=6690nt_BP=284nt
GGCGCCTGGTTGTCAGGCAGTTTTGTAGGAGTTCGGGCCAATTGGAGGCGCAGGCACCGCTCGACCCGGGCGCAGCGCGCAGGCGGTGGC
GAAGAGACGCCGAGCGGGCCGAGTGCGGCCGAGCAAAGCCGGAGCCGGAGCGGGGCCGCAGGAGACGGGCCGGGTCCGGACGGGCCGAGA
TGCCCTATAAACTGAAAAAGGAGAAGGAGCCCCCCAAGGTTGCCAAATGCACAGCCAAGCCTAGCAGCTCGGGCAAGGATGGTGGAGGCG
AGAACACTGAGGAGATCGGACAGCTGGCTTTTAAAGGAATGAAGAGACTCAATAGAATCCAGTCAATAGTGTTTGAGACTGCCTACAACA
CCAATGAGAACATGCTGATTTGTGCCCCTACAGGAGCTGGAAAAACCAACATTGCAATGCTGACAGTCTTGCATGAAATTCGCCAACATT
TTCAACAAGGTGTTATCAAAAAGAATGAATTTAAGATTGTATATGTTGCTCCAATGAAAGCCTTGGCAGCTGAAATGACAGATTACTTCA
GCAGACGTCTAGAGCCACTAGGCATCATTGTGAAAGAATTGACTGGTGACATGCAGTTGTCCAAAAGTGAAATTTTACGAACTCAGATGC
TTGTGACCACACCAGAAAAATGGGATGTAGTGACAAGAAAGAGTGTTGGGGATGTAGCTCTTTCCCAGATTGTAAGGCTCCTTATTCTTG
ATGAAGTTCATTTGCTGCATGAAGATAGAGGACCAGTATTAGAAAGCATAGTTGCCCGTACTTTACGGCAGGTGGAATCCACACAGAGTA
TGATAAGGATTCTCGGACTGTCTGCAACTTTACCTAACTACCTCGATGTTGCCACATTTTTACATGTTAATCCATACATTGGACTTTTCT
TCTTTGATGGCCGTTTTCGACCAGTACCTCTTGGACAGACATTTTTGGGGATTAAATGTGCAAATAAGATGCAGCAGTTGAATAACATGG
ATGAAGTATGTTATGAAAATGTTTTGAAGCAAGTAAAGGCTGGACACCAGGTGATGGTGTTTGTACATGCTCGAAATGCCACTGTAAGAA
CAGCTATGTCTCTAATAGAAAGAGCAAAAAATTGTGGCCATATTCCCTTCTTTTTTCCTACCCAAGGACATGACTATGTACTTGCAGAAA
AACAGGTACAAAGGTCGAGAAATAAGCAAGTACGAGAATTATTCCCAGATGGTTTTAGTATTCATCATGCAGGAATGCTTCGGCAGGACA
GAAATTTAGTTGAAAACTTGTTTTCTAATGGGCATATCAAAGTCCTAGTGTGTACAGCTACGTTAGCCTGGGGTGTCAATCTTCCCGCCC
ATGCTGTTATTATTAAGGGAACACAAATATATGCTGCAAAAAGAGGCTCCTTTGTTGACCTTGGAATTTTAGATGTCATGCAGATATTTG
GTCGAGCTGGACGACCACAATTTGACAAATTTGGGGAAGGAATAATTATAACAACGCATGATAAACTCAGCCATTACCTCACTTTGCTCA
CTCAACGAAACCCAATTGAGAGTCAGTTTCTGGAAAGCCTTGCAGATAACCTAAATGCAGAGATTGCTCTGGGAACAGTTACTAATGTGG
AAGAAGCAGTGAAGTGGATAAGTTACACTTATCTTTATGTACGGATGAGAGCAAATCCATTAGCATATGGCATCAGTCACAAGGCTTATC
AGATTGACCCAACATTAAGAAAGCATCGAGAACAGTTGGTCATTGAAGTTGGACGAAAACTAGACAAAGCTCAGATGATTCGTTTTGAGG
AGCGAACTGGATATTTTTCCTCAACTGATTTGGGTAGAACTGCCAGCCATTACTATATTAAATACAACACCATTGAGACCTTTAATGAAC
TCTTTGATGCTCACAAAACAGAAGGTGATATCTTTGCCATAGTCTCCAAAGCTGAAGAATTTGATCAAATTAAGGTCAGAGAAGAGGAAA
TAGAGGAGTTAGATACCTTATTAAGCAATTTTTGTGAACTCTCCACTCCTGGAGGTGTAGAGAATAGTTATGGGAAAATAAACATCTTAC
TTCAAACTTATATCAGCCGAGGAGAAATGGACAGTTTCTCCCTTATATCAGATTCTGCATATGTTGCACAGAATGCAGCTAGAATTGTCC
GTGCTCTTTTTGAAATTGCTCTGAGGAAACGTTGGCCTACCATGACCTACAGGCTCCTGAATCTTAGTAAAGTCATTGACAAGAGGCTTT
GGGGTTGGGCTAGCCCTTTGAGACAATTTTCAATCCTACCACCACACATCCTAACAAGATTAGAAGAAAAAAAGCTTACTGTGGATAAGC
TGAAAGACATGAGGAAAGATGAAATAGGTCACATTTTACATCATGTGAATATTGGACTGAAGGTCAAACAATGTGTTCATCAGATTCCTT
CTGTTATGATGGAAGCATCCATTCAGCCTATCACAAGGACTGTCCTCCGAGTGACACTCAGCATCTATGCTGATTTCACTTGGAATGATC
AGGTACATGGGACAGTAGGAGAACCTTGGTGGATTTGGGTAGAAGATCCTACAAATGATCATATTTATCATTCAGAGTATTTTCTAGCTC
TAAAAAAACAAGTCATTAGTAAAGAAGCCCAACTACTGGTATTTACAATCCCTATTTTTGAGCCTTTGCCTTCCCAATACTACATCCGAG
CAGTGTCTGATAGATGGTTGGGTGCTGAGGCAGTATGTATTATCAACTTTCAACATCTAATTCTACCAGAGAGACATCCTCCTCATACAG
AATTACTGGATCTTCAGCCTTTACCAATCACAGCTTTGGGATGTAAAGCATATGAAGCCCTGTACAACTTCAGCCACTTTAACCCTGTAC
AGACACAAATATTTCATACATTGTATCACACGGATTGTAATGTCCTACTTGGAGCACCTACTGGATCGGGAAAGACTGTTGCAGCTGAAT
TAGCCATTTTCAGAGTCTTCAACAAATACCCTACTTCAAAGGCGGTATATATTGCACCCCTAAAAGCCCTAGTACGTGAAAGAATGGATG
ATTGGAAAGTTAGAATAGAAGAAAAACTTGGTAAAAAAGTTATTGAACTAACAGGGGATGTGACTCCTGATATGAAATCCATTGCCAAGG
CTGACCTTATCGTCACTACGCCAGAGAAGTGGGATGGAGTCAGCAGAAGCTGGCAAAATAGGAACTATGTTCAGCAAGTCACTATTCTCA
TCATAGATGAGATCCATCTGCTTGGGGAGGAAAGAGGCCCTGTTCTAGAGGTCATTGTATCTCGAACAAATTTTATCTCATCACACACAG
AAAAGCCTGTTAGAATAGTTGGACTATCTACTGCATTAGCTAATGCCAGAGACCTTGCTGATTGGCTCAATATTAAGCAGATGGGCTTGT
TTAACTTCCGACCATCAGTACGCCCAGTTCCACTGGAAGTTCACATTCAAGGCTTTCCAGGTCAACATTACTGTCCTCGTATGGCTAGTA
TGAACAAGCCTGCATTTCAGGCAATTAGAAGCCATTCTCCAGCCAAACCTGTTTTGATATTTGTCTCATCAAGACGTCAAACTCGTCTTA
CTGCTTTGGAATTGATCGCCTTCCTGGCTACTGAAGAAGATCCAAAGCAGTGGTTAAACATGGATGAAAGAGAGATGGAGAACATCATTG
CAACAGTAAGAGATTCCAACCTCAAGCTGACCCTTGCTTTCGGGATAGGAATGCATCATGCTGGACTACATGAGAGGGACCGAAAAACAG
TAGAGGAACTATTTGTAAACTGTAAAGTTCAGGTTCTTATTGCTACAAGCACATTAGCCTGGGGTGTAAACTTTCCAGCTCATTTAGTAA
TTATTAAGGGAACAGAATACTATGATGGAAAAACAAGACGTTATGTGGATTTTCCCATTACAGATGTCCTCCAGATGATGGGGCGTGCTG
GGAGGCCGCAGTTCGATGACCAAGGCAAAGCTGTAATTCTAGTTCATGACATAAAGAAAGACTTTTATAAAAAATTTCTTTATGAACCTT
TCCCAGTAGAATCAAGTTTATTAGGAGTGCTCTCTGACCACTTAAATGCAGAGATTGCTGGTGGTACAATTACATCTAAGCAAGATGCAT
TGGATTATATCACCTGGACTTACTTTTTCCGACGTCTTATCATGAATCCCAGCTATTACAATTTGGGTGATGTGAGCCATGATTCTGTGA
ACAAGTTTCTGTCCCATCTGATTGAGAAGTCCCTGATTGAATTGGAACTTTCCTACTGTATTGAAATTGGAGAGGATAATCGCAGCATTG
AACCTCTAACTTATGGCCGAATTGCCTCCTATTACTATTTGAAGCATCAAACAGTTAAAATGTTCAAGGACCGCTTGAAGCCTGAATGCA
GTACTGAAGAACTGCTTTCAATTCTAAGTGATGCAGAAGAATATACAGATTTGCCAGTGAGACACAATGAAGATCATATGAATAGTGAAC
TGGCAAAATGTCTTCCCATTGAATCAAATCCTCATTCATTTGACAGCCCTCACACCAAAGCACATCTCCTGCTACAGGCACATCTCAGCC
GAGCCATGCTACCCTGCCCAGATTATGACACTGATACCAAAACAGTCTTGGACCAAGCTCTCAGAGTATGTCAGGCAATGCTGGACGTGG
CTGCAAACCAGGGCTGGCTGGTGACTGTCCTGAATATCACCAACCTGATTCAGATGGTGATCCAGGGTCGGTGGTTAAAGGACTCTTCTC
TTCTTACACTACCAAACATAGAAAACCATCATCTTCACCTTTTCAAGAAATGGAAGCCGATTATGAAGGGCCCACATGCTAGGGGTCGGA
CCTCCATCGAGTCCCTTCCTGAACTGATCCATGCCTGTGGAGGGAAAGACCATGTATTTAGCTCCATGGTAGAAAGTGAGCTACATGCTG
CAAAAACGAAACAGGCATGGAATTTCTTATCTCACTTGCCAGTGATAAATGTTGGCATAAGTGTTAAAGGCTCGTGGGATGACTTAGTTG
AAGGACATAATGAACTCTCTGTCTCAACTCTGACTGCAGACAAACGAGATGACAACAAATGGATCAAATTGCATGCTGACCAAGAGTATG
TGCTTCAAGTGAGCTTGCAGAGAGTCCACTTTGGGTTCCACAAGGGAAAGCCAGAGAGCTGTGCAGTTACTCCTCGATTTCCCAAATCAA
AAGACGAAGGATGGTTTTTGATATTAGGAGAAGTGGATAAGAGAGAACTTATTGCTTTGAAAAGAGTAGGATATATTCGAAATCATCATG
TTGCTTCCCTTTCTTTTTATACCCCTGAAATACCTGGAAGGTATATCTACACATTATATTTCATGAGTGACTGCTACCTTGGCCTGGACC
AGCAGTATGACATCTATCTCAACGTTACACAAGCGAGTCTTTCTGCACAGGTCAACACCAAGGTCTCTGATTCCCTGACTGACCTGGCAT
TAAAGTAACTTGACCTGAACAATCCATTTGAAAGGAGTGGCTAAGAATTCTCTCTGTTCAGTCATCTAGACAAATCGAATTACTTGATGT
TTGCCTTGAAAGAATCAACTTCTAACCTCAACCATCCAGGAAATTGACAGTGGCTGCAGTATTGACTCCAGTGACATAAAGTTAACCACA
GTGGCCTTTTAACAAATGTTGCCTTTTATAATGTTATCTTTATGAGTTTCTTGATATGTAAGATGAAAAAGCATTTAGAATAATCTTTTA
ATTTGTGTATATTTGGGATGATATTTAGGAGCTATCAATCAAATTTTACATCTCACAATGTACTGTTTACATGGATATTGGCTGCTTTTT
TTAAGGAAAACCACATTGAGATGTGACAAGTGTTAGGACTTGTCACAGATTTCTAACTCTGCCGCATAAACTATAAATCTGTAAGGTGGT
ACACAGCGTGTCTTGTTAGCAAAATTTATACTTTGATATGATCACATGTAGAAGTAGCTTCAAGAATTTCTTGTAGTCATAAATGTTTAA
TAATATATGATGTAAAATTATATTATGGAGCCTAATGATGATAACAAAGAAAACAATATACTGATCTTAGAAAATGTAGACATGGTTAAC
TGGGAAATAAAATATAGAGTGGCACTTCAAGACAAGCTGACTCAATGTTTTCTTCTGCTTCCTTTAAATAATATCCCCTTACTCATCTGT
TCTTCTTTTCTTTCCCTTCTACTTCAAGGCTTTATTTCTATTATCTTTCTGACATATTTATTTACAGAAGTAGAGAAGTATAATCTAATT
CATGTTGTAGCACTTACAGATCATATAGTACAATTATTTGTCTTTATGCTCTCCAGGAAAAATCTGAGACAGAAAATTTTTCACCCCTAT
GGATAGGTTTTCACCTGTAATAAAGAAAATTTCTCTATGTCCAAACAAATTCCTTCTTGAAAAATACTTTTTCAAACTAAAAACTTGTTA
AAATTCAATGTTCATATAATATGCATTCTAGTGGAATGAAATTCTACCTTTGTGAAATAATTTCAGTTTTCTTAGCCCTAAAATGAATTA
TTTTAAAACATTTTCCAATGTCATTGTTACAAATACTAGAATTTAAGTGTTTCTGAAATTGGAATGTATTGCTTGTATATATCCTTTTCC

>68088_68088_5_PPP2R5D-ASCC3_PPP2R5D_chr6_42957426_ENST00000485511_ASCC3_chr6_101215221_ENST00000369162_length(amino acids)=1830AA_BP=93
MVVRQFCRSSGQLEAQAPLDPGAARRRWRRDAERAECGRAKPEPERGRRRRAGSGRAEMPYKLKKEKEPPKVAKCTAKPSSSGKDGGGEN
TEEIGQLAFKGMKRLNRIQSIVFETAYNTNENMLICAPTGAGKTNIAMLTVLHEIRQHFQQGVIKKNEFKIVYVAPMKALAAEMTDYFSR
RLEPLGIIVKELTGDMQLSKSEILRTQMLVTTPEKWDVVTRKSVGDVALSQIVRLLILDEVHLLHEDRGPVLESIVARTLRQVESTQSMI
RILGLSATLPNYLDVATFLHVNPYIGLFFFDGRFRPVPLGQTFLGIKCANKMQQLNNMDEVCYENVLKQVKAGHQVMVFVHARNATVRTA
MSLIERAKNCGHIPFFFPTQGHDYVLAEKQVQRSRNKQVRELFPDGFSIHHAGMLRQDRNLVENLFSNGHIKVLVCTATLAWGVNLPAHA
VIIKGTQIYAAKRGSFVDLGILDVMQIFGRAGRPQFDKFGEGIIITTHDKLSHYLTLLTQRNPIESQFLESLADNLNAEIALGTVTNVEE
AVKWISYTYLYVRMRANPLAYGISHKAYQIDPTLRKHREQLVIEVGRKLDKAQMIRFEERTGYFSSTDLGRTASHYYIKYNTIETFNELF
DAHKTEGDIFAIVSKAEEFDQIKVREEEIEELDTLLSNFCELSTPGGVENSYGKINILLQTYISRGEMDSFSLISDSAYVAQNAARIVRA
LFEIALRKRWPTMTYRLLNLSKVIDKRLWGWASPLRQFSILPPHILTRLEEKKLTVDKLKDMRKDEIGHILHHVNIGLKVKQCVHQIPSV
MMEASIQPITRTVLRVTLSIYADFTWNDQVHGTVGEPWWIWVEDPTNDHIYHSEYFLALKKQVISKEAQLLVFTIPIFEPLPSQYYIRAV
SDRWLGAEAVCIINFQHLILPERHPPHTELLDLQPLPITALGCKAYEALYNFSHFNPVQTQIFHTLYHTDCNVLLGAPTGSGKTVAAELA
IFRVFNKYPTSKAVYIAPLKALVRERMDDWKVRIEEKLGKKVIELTGDVTPDMKSIAKADLIVTTPEKWDGVSRSWQNRNYVQQVTILII
DEIHLLGEERGPVLEVIVSRTNFISSHTEKPVRIVGLSTALANARDLADWLNIKQMGLFNFRPSVRPVPLEVHIQGFPGQHYCPRMASMN
KPAFQAIRSHSPAKPVLIFVSSRRQTRLTALELIAFLATEEDPKQWLNMDEREMENIIATVRDSNLKLTLAFGIGMHHAGLHERDRKTVE
ELFVNCKVQVLIATSTLAWGVNFPAHLVIIKGTEYYDGKTRRYVDFPITDVLQMMGRAGRPQFDDQGKAVILVHDIKKDFYKKFLYEPFP
VESSLLGVLSDHLNAEIAGGTITSKQDALDYITWTYFFRRLIMNPSYYNLGDVSHDSVNKFLSHLIEKSLIELELSYCIEIGEDNRSIEP
LTYGRIASYYYLKHQTVKMFKDRLKPECSTEELLSILSDAEEYTDLPVRHNEDHMNSELAKCLPIESNPHSFDSPHTKAHLLLQAHLSRA
MLPCPDYDTDTKTVLDQALRVCQAMLDVAANQGWLVTVLNITNLIQMVIQGRWLKDSSLLTLPNIENHHLHLFKKWKPIMKGPHARGRTS
IESLPELIHACGGKDHVFSSMVESELHAAKTKQAWNFLSHLPVINVGISVKGSWDDLVEGHNELSVSTLTADKRDDNKWIKLHADQEYVL
QVSLQRVHFGFHKGKPESCAVTPRFPKSKDEGWFLILGEVDKRELIALKRVGYIRNHHVASLSFYTPEIPGRYIYTLYFMSDCYLGLDQQ

--------------------------------------------------------------
>68088_68088_6_PPP2R5D-ASCC3_PPP2R5D_chr6_42957426_ENST00000485511_ASCC3_chr6_101215221_ENST00000522650_length(transcript)=1372nt_BP=284nt
GGCGCCTGGTTGTCAGGCAGTTTTGTAGGAGTTCGGGCCAATTGGAGGCGCAGGCACCGCTCGACCCGGGCGCAGCGCGCAGGCGGTGGC
GAAGAGACGCCGAGCGGGCCGAGTGCGGCCGAGCAAAGCCGGAGCCGGAGCGGGGCCGCAGGAGACGGGCCGGGTCCGGACGGGCCGAGA
TGCCCTATAAACTGAAAAAGGAGAAGGAGCCCCCCAAGGTTGCCAAATGCACAGCCAAGCCTAGCAGCTCGGGCAAGGATGGTGGAGGCG
AGAACACTGAGGAGATCGGACAGCTGGCTTTTAAAGGAATGAAGAGACTCAATAGAATCCAGTCAATAGTGTTTGAGACTGCCTACAACA
CCAATGAGAACATGCTGATTTGTGCCCCTACAGGAGCTGGAAAAACCAACATTGCAATGCTGACAGTCTTGCATGAAATTCGCCAACATT
TTCAACAAGGTGTTATCAAAAAGAATGAATTTAAGATTGTATATGTTGCTCCAATGAAAGCCTTGGCAGCTGAAATGACAGATTACTTCA
GCAGACGTCTAGAGCCACTAGGCATCATTGTGAAAGAATTGACTGGTGACATGCAGTTGTCCAAAAGTGAAATTTTACGAACTCAGATGC
TTGTGACCACACCAGAAAAATGGGATGTAGTGACAAGAAAGAGTGTTGGGGATGTAGCTCTTTCCCAGATTGTAAGGCTCCTTATTCTTG
ATGAAGTTCATTTGCTGCATGAAGATAGAGGACCAGTATTAGAAAGCATAGTTGCCCGTACTTTACGGCAGGTGGAATCCACACAGAGTA
TGATAAGGATTCTCGGACTGTCTGCAACTTTACCTAACTACCTCGATGTTGCCACATTTTTACATGTTAATCCATACATTGGACTTTTCT
TCTTTGATGGCCGTTTTCGACCAGTACCTCTTGGACAGACATTTTTGGGGATTAAATGTGCAAATAAGATGCAGCAGTTGAATAACATGG
ATGAAGTATGTTATGAAAATGTTTTGAAGCAAGTAAAGGCTGGACACCAGGTACACTTATTTTATCTGCTTTTACACTTATTTATCTGCT
TTTAGAGAGTGCTTAATGATAAAAATTATTAATATTTACGCTCTTCAGAAGAAAATTTTTCTTTAATTCTGAGGCAATGACTCAGAGGTT
CTAATTCTTAATAACTGCTTTAGCCCAATGGGTAAGTCATAAAAATATTCATAGATATTATCATCCCAGTATTGATAGGTCGTGCTATTT
TGTTTGCCATTTTTAATTTTAAATATTATATTCTTACTGTTTTCATGAAGCAATATCAATTGAAATGTAATATATATAATAAAGTTCTGT

>68088_68088_6_PPP2R5D-ASCC3_PPP2R5D_chr6_42957426_ENST00000485511_ASCC3_chr6_101215221_ENST00000522650_length(amino acids)=359AA_BP=93
MVVRQFCRSSGQLEAQAPLDPGAARRRWRRDAERAECGRAKPEPERGRRRRAGSGRAEMPYKLKKEKEPPKVAKCTAKPSSSGKDGGGEN
TEEIGQLAFKGMKRLNRIQSIVFETAYNTNENMLICAPTGAGKTNIAMLTVLHEIRQHFQQGVIKKNEFKIVYVAPMKALAAEMTDYFSR
RLEPLGIIVKELTGDMQLSKSEILRTQMLVTTPEKWDVVTRKSVGDVALSQIVRLLILDEVHLLHEDRGPVLESIVARTLRQVESTQSMI

--------------------------------------------------------------

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Fusion Gene PPI Analysis for PPP2R5D-ASCC3


check button Go to ChiPPI (Chimeric Protein-Protein interactions) to see the chimeric PPI interaction in

ChiPPI page.


check button Protein-protein interactors with each fusion partner protein in wild-type (BIOGRID-3.4.160)
HgeneHgene's interactorsTgeneTgene's interactors


check button - Retained PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenStill interaction with


check button - Lost PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


check button - Retained PPIs, but lost function due to frame-shift fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


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Related Drugs for PPP2R5D-ASCC3


check button Drugs targeting genes involved in this fusion gene.
(DrugBank Version 5.1.8 2021-05-08)
PartnerGeneUniProtAccDrugBank IDDrug nameDrug activityDrug typeDrug status

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Related Diseases for PPP2R5D-ASCC3


check button Diseases associated with fusion partners.
(DisGeNet 4.0)
PartnerGeneDisease IDDisease name# pubmedsSource