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Center for Computational Systems Medicine
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Fusion Gene Summary

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Fusion Gene ORF analysis

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Fusion Genomic Features

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Fusion Protein Features

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Fusion Gene Sequence

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Fusion Gene PPI analysis

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Related Drugs

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Related Diseases

Fusion gene:PPWD1-NLN (FusionGDB2 ID:68346)

Fusion Gene Summary for PPWD1-NLN

check button Fusion gene summary
Fusion gene informationFusion gene name: PPWD1-NLN
Fusion gene ID: 68346
HgeneTgene
Gene symbol

PPWD1

NLN

Gene ID

23398

57486

Gene namepeptidylprolyl isomerase domain and WD repeat containing 1neurolysin
Synonyms-AGTBP|EP24.16|MEP|MOP
Cytomap

5q12.3

5q12.3

Type of geneprotein-codingprotein-coding
Descriptionpeptidylprolyl isomerase domain and WD repeat-containing protein 1epididymis secretory sperm binding proteinspliceosome-associated cyclophilinneurolysin, mitochondrialangiotensin binding proteinendopeptidase 24.16microsomal endopeptidasemitochondrial oligopeptidase Mneurolysin (metallopeptidase M3 family)neurotensin endopeptidase
Modification date2020031320200313
UniProtAcc.

Q9BYT8

Ensembl transtripts involved in fusion geneENST00000261308, ENST00000535264, 
ENST00000538977, 		ENST00000515595, 
ENST00000380985, ENST00000502464, 
Fusion gene scores* DoF score4 X 4 X 3=487 X 9 X 6=378
# samples 410
** MAII scorelog2(4/48*10)=-0.263034405833794
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0		log2(10/378*10)=-1.91838623444635
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0
Context

PubMed: PPWD1 [Title/Abstract] AND NLN [Title/Abstract] AND fusion [Title/Abstract]

Most frequent breakpointPPWD1(64875440)-NLN(65076006), # samples:2
Anticipated loss of major functional domain due to fusion event.
* DoF score (Degree of Frequency) = # partners X # break points X # cancer types
** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10)

check button Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez
PartnerGeneGO IDGO termPubMed ID
HgenePPWD1

GO:0000413

protein peptidyl-prolyl isomerization

20676357


check buttonFusion gene breakpoints across PPWD1 (5'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.
all structure

check buttonFusion gene breakpoints across NLN (3'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.
all structure

check button Fusion gene information from two resources (ChiTars 5.0 and ChimerDB 4.0)
* All genome coordinats were lifted-over on hg19.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
SourceDiseaseSampleHgeneHchrHbpHstrandTgeneTchrTbpTstrand
ChimerDB4LUADTCGA-50-5930-01APPWD1chr5

64875440

+NLNchr5

65076006

+


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Fusion Gene ORF analysis for PPWD1-NLN

check button Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
ORFHenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrand
5CDS-intronENST00000261308ENST00000515595PPWD1chr5

64875440

+NLNchr5

65076006

+
5CDS-intronENST00000535264ENST00000515595PPWD1chr5

64875440

+NLNchr5

65076006

+
5CDS-intronENST00000538977ENST00000515595PPWD1chr5

64875440

+NLNchr5

65076006

+
In-frameENST00000261308ENST00000380985PPWD1chr5

64875440

+NLNchr5

65076006

+
In-frameENST00000261308ENST00000502464PPWD1chr5

64875440

+NLNchr5

65076006

+
In-frameENST00000535264ENST00000380985PPWD1chr5

64875440

+NLNchr5

65076006

+
In-frameENST00000535264ENST00000502464PPWD1chr5

64875440

+NLNchr5

65076006

+
In-frameENST00000538977ENST00000380985PPWD1chr5

64875440

+NLNchr5

65076006

+
In-frameENST00000538977ENST00000502464PPWD1chr5

64875440

+NLNchr5

65076006

+

check buttonORFfinder result based on the fusion transcript sequence of in-frame fusion genes.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandSeq length
(transcript)		BP loci
(transcript)		Predicted start
(transcript)		Predicted stop
(transcript)		Seq length
(amino acids)
ENST00000261308PPWD1chr564875440+ENST00000380985NLNchr565076006+93471422392978979
ENST00000261308PPWD1chr564875440+ENST00000502464NLNchr565076006+93471422392978979
ENST00000535264PPWD1chr564875440+ENST00000380985NLNchr565076006+932714021422958938
ENST00000535264PPWD1chr564875440+ENST00000502464NLNchr565076006+932714021422958938
ENST00000538977PPWD1chr564875440+ENST00000380985NLNchr565076006+918412591582815885
ENST00000538977PPWD1chr564875440+ENST00000502464NLNchr565076006+918412591582815885

check buttonDeepORF prediction of the coding potential based on the fusion transcript sequence of in-frame fusion genes. DeepORF is a coding potential classifier based on convolutional neural network by comparing the real Ribo-seq data. If the no-coding score < 0.5 and coding score > 0.5, then the in-frame fusion transcript is predicted as being likely translated.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandNo-coding scoreCoding score
ENST00000261308ENST00000380985PPWD1chr564875440+NLNchr565076006+0.0001218090.99987817
ENST00000261308ENST00000502464PPWD1chr564875440+NLNchr565076006+0.0001218090.99987817
ENST00000535264ENST00000380985PPWD1chr564875440+NLNchr565076006+0.000132230.9998678
ENST00000535264ENST00000502464PPWD1chr564875440+NLNchr565076006+0.000132230.9998678
ENST00000538977ENST00000380985PPWD1chr564875440+NLNchr565076006+9.74E-050.9999026
ENST00000538977ENST00000502464PPWD1chr564875440+NLNchr565076006+9.74E-050.9999026

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Fusion Genomic Features for PPWD1-NLN


check buttonFusionAI prediction of the potential fusion gene breakpoint based on the pre-mature RNA sequence context (+/- 5kb of individual partner genes, total 20kb length sequence). FusionAI is a fusion gene breakpoint classifier based on convolutional neural network by comparing the fusion positive and negative sequence context of ~ 20K fusion gene data. From here, we can have the relative potentency of the 20K genomic sequence how individual sequnce will be likely used as the gene fusion breakpoints.
HgeneHchrHbpHstrandTgeneTchrTbpTstrand1-pp (fusion gene breakpoint)
PPWD1chr564875440+NLNchr565076005+0.0001033850.99989665
PPWD1chr564875440+NLNchr565076005+0.0001033850.99989665

check buttonDistribution of 44 human genomic features loci across 20kb length fusion breakpoint regions. We integrated a total of 44 different types of human genomic feature loci information across five big categories including virus integration sites, repeats, structural variants, chromatin states, and gene expression regulation. More details are in help page.
genomic feature

check buttonDistribution of 44 human genomic features loci across 20kb length fusion breakpoint regions that are ovelapped with the top 1% feature importance score regions. More details are in help page.
genomic feature of top 1%

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Fusion Protein Features for PPWD1-NLN


check button Four levels of functional features of fusion genes
Go to FGviewer search page for the most frequent breakpoint (https://ccsmweb.uth.edu/FGviewer/chr5:64875440/chr5:65076006)
- FGviewer provides the online visualization of the retention search of the protein functional features across DNA, RNA, protein, and pathological levels.
- How to search
1. Put your fusion gene symbol.
2. Press the tab key until there will be shown the breakpoint information filled.
4. Go down and press 'Search' tab twice.
4. Go down to have the hyperlink of the search result.
5. Click the hyperlink.
6. See the FGviewer result for your fusion gene.
FGviewer

check buttonMain function of each fusion partner protein. (from UniProt)
HgeneTgene
.NLN

Q9BYT8

FUNCTION: Transcriptional activator which is required for calcium-dependent dendritic growth and branching in cortical neurons. Recruits CREB-binding protein (CREBBP) to nuclear bodies. Component of the CREST-BRG1 complex, a multiprotein complex that regulates promoter activation by orchestrating a calcium-dependent release of a repressor complex and a recruitment of an activator complex. In resting neurons, transcription of the c-FOS promoter is inhibited by BRG1-dependent recruitment of a phospho-RB1-HDAC1 repressor complex. Upon calcium influx, RB1 is dephosphorylated by calcineurin, which leads to release of the repressor complex. At the same time, there is increased recruitment of CREBBP to the promoter by a CREST-dependent mechanism, which leads to transcriptional activation. The CREST-BRG1 complex also binds to the NR2B promoter, and activity-dependent induction of NR2B expression involves a release of HDAC1 and recruitment of CREBBP (By similarity). {ECO:0000250}.FUNCTION: Hydrolyzes oligopeptides such as neurotensin, bradykinin and dynorphin A. {ECO:0000250}.

check buttonRetention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at

download page


* Minus value of BPloci means that the break pointn is located before the CDS.
- In-frame and retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
HgenePPWD1chr5:64875440chr5:65076006ENST00000261308+71112_17450647.0Compositional biasNote=Poly-Arg
HgenePPWD1chr5:64875440chr5:65076006ENST00000261308+711124_162450647.0RepeatNote=WD 2
HgenePPWD1chr5:64875440chr5:65076006ENST00000261308+711168_208450647.0RepeatNote=WD 3
HgenePPWD1chr5:64875440chr5:65076006ENST00000261308+711213_252450647.0RepeatNote=WD 4
HgenePPWD1chr5:64875440chr5:65076006ENST00000261308+711271_309450647.0RepeatNote=WD 5
HgenePPWD1chr5:64875440chr5:65076006ENST00000261308+711345_386450647.0RepeatNote=WD 6
HgenePPWD1chr5:64875440chr5:65076006ENST00000261308+711401_453450647.0RepeatNote=WD 7
HgenePPWD1chr5:64875440chr5:65076006ENST00000261308+71180_118450647.0RepeatNote=WD 1

- In-frame and not-retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
HgenePPWD1chr5:64875440chr5:65076006ENST00000261308+711490_645450647.0DomainPPIase cyclophilin-type


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Fusion Gene Sequence for PPWD1-NLN


check button For in-frame fusion transcripts, we provide the fusion transcript sequences and fusion amino acid sequences. To have fusion amino acid sequence, we ran ORFfinder and chose the longest ORF among the all predicted ones.
>68346_68346_1_PPWD1-NLN_PPWD1_chr5_64875440_ENST00000261308_NLN_chr5_65076006_ENST00000380985_length(transcript)=9347nt_BP=1422nt
AGAAGACTGCGCCGCTGCTTTGGGATTGGTAGCTGAGTTTTGTGTCGCGCCTTTTCTGACGATGCGAACAACATGGCGGCGGAAAGTGGT
AGCGATTTTCAGCAGAGACGTAGAAGGCGCCGGGACCCGGAGGAACCGGAAAAAACAGAACTCAGCGAAAGAGAGCTGGCAGTAGCAGTG
GCGGTGTCCCAGGAGAACGATGAGGAGAACGAAGAGCGCTGGGTTGGACCTTTACCTGTGGAGGCAACACTGGCCAAGAAGAGGAAAGTC
TTAGAGTTTGAAAGAGTCTATCTTGATAATCTCCCCAGTGCATCCATGTATGAGCGCAGTTACATGCATAGAGATGTTATCACCCATGTG
GTATGCACCAAAACAGATTTTATTATTACTGCCAGTCATGATGGACATGTCAAGTTCTGGAAAAAAATAGAAGAGGGAATTGAATTTGTT
AAACATTTTCGTAGTCACCTGGGAGTTATTGAGAGTATTGCAGTTAGCTCTGAGGGAGCATTGTTCTGTTCTGTGGGTGATGATAAAGCA
ATGAAGGTGTTTGATGTAGTGAACTTTGACATGATCAACATGCTGAAACTTGGCTATTTTCCTGGACAGTGTGAGTGGATCTATTGCCCA
GGGGATGCAATTTCTTCAGTTGCTGCTTCCGAAAAGAGTACAGGAAAAATTTTCATTTATGATGGCCGAGGAGATAACCAGCCACTTCAT
ATTTTTGACAAACTCCATACATCACCTCTTACTCAGATACGGCTAAACCCAGTTTACAAAGCAGTAGTGTCTTCTGACAAATCTGGGATG
ATTGAATACTGGACTGGGCCTCCTCATGAATATAAATTCCCCAAAAATGTGAACTGGGAATATAAAACTGACACTGATTTATATGAATTT
GCCAAGTGTAAGGCTTATCCAACCAGCGTATGTTTTTCACCAGATGGGAAGAAAATAGCTACTATTGGTTCTGATAGAAAAGTTAGAATT
TTCAGATTTGTAACTGGAAAACTCATGAGAGTCTTTGATGAATCACTAAGCATGTTTACTGAACTGCAACAGATGAGGCAACAGTTACCA
GACATGGAATTTGGCCGACGAATGGCTGTAGAACGTGAGTTGGAGAAGGTTGATGCTGTAAGATTAATTAATATAGTTTTTGATGAAACT
GGACACTTCGTGCTGTATGGAACAATGCTGGGCATTAAAGTTATAAATGTAGAGACAAACCGGTGTGTGCGGATTTTAGGCAAACAAGAA
AATATTAGAGTGATGCAATTGGCTTTGTTCCAGGGGATAGCCAAAAAGCATCGTGCTGCAACTACTATAGAAATGAAAGCTTCTGAAAAT
CCTGTTCTTCAGAATATTCAAGCTGACCCAACAATAGTCTGTACATCATTCAAAAAGAATAGATTTTATATGGAAATCAAATCAATGAAG
AAAAGAATGAGTGAGCTATGTATTGATTTTAACAAAAACCTCAATGAGGATGATACCTTCCTTGTATTTTCCAAGGCTGAACTTGGTGCT
CTTCCTGATGATTTCATTGACAGTTTAGAAAAGACAGATGATGACAAGTATAAAATTACCTTAAAATATCCACACTATTTCCCTGTCATG
AAGAAATGTTGTATCCCTGAAACCAGAAGAAGGATGGAAATGGCTTTTAATACAAGGTGCAAAGAGGAAAACACCATAATTTTGCAGCAG
CTACTCCCACTGCGAACCAAGGTGGCCAAACTACTCGGTTATAGCACACATGCTGACTTCGTCCTTGAAATGAACACTGCAAAGAGCACA
AGCCGCGTAACAGCCTTTCTAGATGATTTAAGCCAGAAGTTAAAACCCTTGGGTGAAGCAGAACGAGAGTTTATTTTGAATTTGAAGAAA
AAGGAATGCAAAGACAGGGGTTTTGAATATGATGGGAAAATCAATGCCTGGGATCTATATTACTACATGACTCAGACAGAGGAACTCAAG
TATTCCATAGACCAAGAGTTCCTCAAGGAATACTTCCCAATTGAGGTGGTCACTGAAGGCTTGCTGAACACCTACCAGGAGTTGTTGGGA
CTTTCATTTGAACAAATGACAGATGCTCATGTTTGGAACAAGAGTGTTACACTTTATACTGTGAAGGATAAAGCTACAGGAGAAGTATTG
GGACAGTTCTATTTGGACCTCTATCCAAGGGAAGGAAAATACAATCATGCGGCCTGCTTCGGTCTCCAGCCTGGCTGCCTTCTGCCTGAT
GGAAGCCGGATGATGGCAGTGGCTGCCCTCGTGGTGAACTTCTCACAGCCAGTGGCAGGTCGTCCCTCTCTCCTGAGACACGACGAGGTG
AGGACTTACTTTCATGAGTTTGGTCACGTGATGCATCAGATTTGTGCACAGACTGATTTTGCACGATTTAGCGGAACAAATGTGGAAACT
GACTTTGTAGAGGTGCCATCGCAAATGCTTGAAAATTGGGTGTGGGACGTCGATTCCCTCCGAAGATTGTCAAAACATTATAAAGATGGA
AGCCCTATTGCAGACGATCTGCTTGAAAAACTTGTTGCTTCTAGGCTGGTCAACACAGGTCTTCTGACCCTGCGCCAGATTGTTTTGAGC
AAAGTTGATCAGTCTCTTCATACCAACACATCGCTGGATGCTGCAAGTGAATATGCCAAATACTGCTCAGAAATATTAGGAGTTGCAGCT
ACTCCAGGCACAAATATGCCAGCTACCTTTGGACATTTGGCAGGGGGATACGATGGCCAATATTATGGATATCTTTGGAGTGAAGTATTT
TCCATGGATATGTTTTACAGCTGTTTTAAAAAAGAAGGGATAATGAATCCAGAGGTTGGAATGAAATACAGAAACCTAATCCTGAAACCT
GGGGGATCTCTGGACGGCATGGACATGCTCCACAATTTCTTGAAACGTGAGCCAAACCAAAAAGCGTTCCTAATGAGTAGAGGCCTGCAT
GCTCCGTGAACTGGGGATCTTTGGTAGCCGTCCATGTCTGGAGGACAAGTCGACATCACCATGTGTTACTGGCCTGGAAACTGAAGGGAG
TTTTGCAAGTGAAAATTTAGATTTCTATTGACATCCTTTTGTTTTCTAATTTTAAAAATTATAAAGATGTAAATGGAATTATAAATACTG
TGACCTAAGAAAAGACCCACTAGAAAGTAATTGTACTATAAAATTTCATAAAACTGGATTTGATTTCTTTTTATGAAAGTTTCATATGAA
TGTAACTTGATTTTTTACTATTATAATCTAGATAATATGATATAAGAGGGCTAAGAATTTTTAAATTGAATCATATATATGATATAATTT
GATCCTTCTTGTATCTTGAAGTTTTGTACTTGGGATTTCTGGACTGATAAATGAATCATCACATTCTTCTGGTAAATATTTTCTTGGAGC
TCTGTGTCAACTTTGATCCTTTGTCTCCCAGGAAGGTGTGACCTCTCCTTTGCCTGCATACCTCAAGGCCAGGGGAATATGCCTCAGTGA
TGCATTTATCTTTGTATATCAGGCCGCATGATTCCCAACTTTCTGCCACACTTAAATTACGTTCCTCCATTTCAGTTTTGTCTTTTCTGT
CTAAAGTTCAGTCAAAGAGTATCAAAAAATTATGTTTCAGCTAGACTGGTGTAATGTATAAGTTTTTGTATCTTGTATTAGAGGATTTCG
TAGCTTTTATTAGAGGCTCATTTCCACCTCAGCATACAAGATCGTTAGTCTTTTGGCATGTGTGCCAATTAGAATACTAAAGCAAGTCCA
AGCACATTTTTCTCTTCTCACGTTTCTAATAAGTGTTAGGGACTTTGCCTCTTTTACTTACCACGTCCCCAAAAGTGTCAGGTAGACATG
TCACAAATGGCTCTGTAGAGAGCCATGGGAAGAGAGAGGAGGTGGATGTGGAACATAAAGGGTTCAGAAACTCCAGAAGAGGAGTGGGTT
TTGGATAGAAGCATTTGAGGACAGCTGCTCCAAAGCCTTATGTGTATGATGAAACTTAACCACGGGGAAGAGACTCTTCAGTAGCCTGTT
CTGTCTGGTGATTTTTATTTTAAGTGAACCTTTGGATCTATCTTTAACTCTCTTTATTGTGAGTCTAAATTCCAATTCTGCAGCAGATCA
GTAAACTCACAGTATTTTTCCTGTGGAAATCTATTCAATAAGGAAACCAAGACAGGATAATAAAATTTAAAAAAAAAACAACTTTGAATT
CCCCTGCCTAGGTCTTCCAGTTGTTTTCCAGCGCATACCTCAGGTATGACTTTGCTAGCCGGGGACAAAATTAGCACCTTCCGATTCTCT
AGTCCAAATGAACTTTGTGCTAAATAAAAAATTATTATACTACATAATAAAGTTACAGATAGCAGGAAATGCAAGAGCTAGGAGATTCCT
AGATTATATCTGCCAAGCAAATACCTTAAACATCCACCTGAAATCCTACTACCCCCTCTTCTGAGATAATTTGCCCAGCCCTTCTCTTCC
CACACACTCACTCAATGTCACCCCCTTCTAATCCCCAAAACTGTTTTTGTGGTCTTTGTAGCCTATAGTAGTTTTCTCACATCTTTCCCC
CTAGACTTTTCTGTTTTTCAGTTTCAGACAAAAAAACTCTTCAGCTTTTTCCAGTGTGTCTCCTTAACAGTAACTTTACCACTTGAAATC
TTATTTCATAGAAAAACTAAATTGGTGTGGAAAGGCTGCACACAATAAAGTTATATTATTATCCATGAAAATGAACTCATATTTCTTTCA
TACTTTAACGTTAAAACCGAAATGCATGAGAGCAAAAGCACCATGGTGTTCTTTCTATTTAGGGCCTACCTCTAATATTTAAAATCTACC
AAAGAGCAGTCACAAAATTAAAACTCAGCCCGGGCGCAGTGGCTCATGCCTGTAATCCCAGCACTTTGGGAGGCCAAGGCAGGAGGATCA
CCTGAGGTCAGAGTTCAAGACCAGCATGGTCAACATGGTGAAACCCTGTCTCTACAAAAATACAAAAAGCTGGGCATGATGTTGGGTTCC
TGTAGTCCCAGCTACTTAGGAGGCTGAGGCAGGAGAATAGCTTGAACCCGGGAGGTGGAGGTTGCAGTGAGCTGAGATCATGCCATTGCA
CTCCAGCCTGGACGACAGAGTGAGATTCAGTCTCAAAAAAAATTAATACTCAAAGAATTATCTAGCATAATTTAAAAGAAAGGACTTTTT
AAAAATTCTCTAGCATAATTCAAAAGAAAGGACTTAACTTTTTTTTTTTTAGTGTGGTCATCCGTCTAGTTGTTCTTTTTTTCCAGATCA
GAGCAGAGAATATCACTGACATGCTTGAAATGGTGGATAACTATGTAAATTGTAATTGGACAAATGTACACTTTAGATTTATGGACTGAG
CCACATATAATAAGGTCTCTCCTGGTAATTGATCCAGGGGATTTAGGCCTCTTTCGGGTTTTTTGTTTTTTTTTTAGGCATTGTTATGTT
GTGAAGGATAAAATCTTCAACATCTTATGCAAATGGATAGTAGGCATGATCCTAAAGGTTTAGTTTTACGATGCTGCAGAGAAGAGAAAT
GTCTTGACGTTTTGCCACCTGATGTAGACTTTGTCCCCCTCTAGTATAAATGTTGCATGTTACCTAGATAAACAACTAAAAATTGCCTTG
AGTTATCACCTGAGCTACTTATGCCAAGGTCTTGCCTTTCTAAAGCTAATAAGGTGAGAGGTGGATATCTGTAGCTCTTCGGATGAAAAA
TTGCATTGTGGGAGATACCAAAATTGAGGAAATAGCTCTTCAAAGAAAAATTACTGATATGATCATTGTACTTGTAAATGCCTTAAGTAG
CAGGCAGTGACTCAATTTTCTACTTTACCATTTTACCTTTAGCTTTTATGTATGAATTATAGGTCTGTGGAGATTCTGCCTCCCCACTAG
GCCAGTGTGTGTTTACCATTTATTCATTTTCTATCATACACAGGTGGATTAAAATTTACATTAAAATTTACATTAAAATACCATCATACT
TCAGGCTTCTATAACAAAATATCAGACTGGGTGGCTTCAAAAGCAGACATTTCTTACAGTTCTGGAAGCTGGGAAGTCCCACAATCCACA
TGCTGGTAAATTTGGTTCGTGGTGAGGCCCCTCTTCCTCTTTTACTGACCACATCCCCAAAAGTGTCAGGTAGACATGTTACAAATAGCT
CTGTAGAGAGCCATGGGAAGAGACAGGAGGCAGATGTGGAACATAAAGGGTTTAGAAACTTCTGCAGGCAGCAGTGGCAGGGAGCAAGCC
CTAGAGTGTCTCTTTTTACGAGAGCAGGAATCCCATCATGAGAGTTCCTTCCTCATGACTTTATCTAAACCCAGTCACCCCCAACAAAGG
CCCCACCCCCTAACCCCATCACATTGGCTGTTACGGCTTCAATGTAGGGGATGGGGCACAAACATTCAGTCCATAACGAATACTGATTCC
TCAAATAGGGTTTAAACATAGTTAACTGAGCCCCCAAAGAATGTTAAAAGAGAAAATCCATTTTATTTGAATAGATGCAGTGACCACAGC
TTCTTCCCTCAAATCAACACATTACAGTTAGATGTCTCCCATCTGAAATTGGATAGCCCACTGAAATTGAACATGCCTTCTCTTATAAAT
GTGTGGTGAGAATAAAAGCAACAAAGAAATGAATGTGGTGGCTCACACCTGTAATCCTAACACTTTGGAAGGTTGAGGCAGGAGGATCCT
TTGTGCTCAAGAGTTTGAGACCAGCCTGAGCAACACAGTGAGACCCTGTCTCTACAAAAACTAAAAAAATTAGCTAGGGATGGTGGCACA
TGCCTGTAGTCCCAGCTACTTGGGAGGCTGAGGTGGGAGGATTGCTTGAGCCCAAGAAGGTCAAGGCTGCCATGAGCCATAATCACGCCA
CTGCACTCCAGCCTGGGTGACAGAGACCCTGTCTTAAAATAAAATAAAAAAAAAAGGAAAAGGAAAGACATACATACCCTCAGTTCTTCG
AAAAACAGTCAACGTCCAAAAAGTTTATTTTTTGAGTCACCTTTAATAGAGAAATTTCCCACTGGAAACAGATCCACCTAAGTGATTATC
TAGTATCAGCTGTATCAAGGCAAAAGGTAAAGGTTATAAGATGTAAATATTAGACCAAAATAGCCTTTTTTAACAAACACAATAATGCTG
TACGTCTGTAACAAAACAAAATTTGAAAAATTGAGGTAATGTACACAGCGATGCACACACCCCCACACCACACCGTGATTCCTGAGTTTT
GATTTGGTTGAATTCACCTTGTAGTTCCCTTTCCTGAGAAAATACAGGTTCAACACATCTAGTCCACGATGTACGTACAAGGGGAAGGGG
TGAACAGGAAATAGACTCCCTTATTCTGCTCACATGAGCTGGAACCTGTACTAGCTGCATATTTCATAGACCCCAGAGGCTCACCTCAAT
TGTACTCCTATGATAAAATGTCTCTAGCATTTGTCATGAGAGAAACTGGCTAGAAATAGTTTGTTCATTGCGTCCAGCAAGACACGCATT
GCTGTTGATATCTTTGTGGCTAAGATGGAGAATGTGACTGGATAATAGTTATCCAGGTGGATTACTAGCTATTGAAACAGTCTGAGATAG
TTGCATGATGATTAACGTTAAACTGGGAGTAATTTCAAGTCATTTGGCTAAAAATGAAAAAAAAGTCCCATAAAAAGGTATCAAATGTAC
AGATAATAGGGCTGGAATTATTAAGTATGATGATGTTATTAACATCTAAAATTATTTTGGCCGGGCAAGGTGGGTCACGCCTGTAATCTC
AGCACTTTGGGATGCCAAGATGGGTGGATCACCTGAGTTCAGGAGTTCAAGACCAGCTTGGCCAACATGGCGAAACCCGTCTCTACTAAA
GAATACAAAAATTAGCCAGGTGTTGTGGCACATGCCTGTACTCCCAGCTACTCAGGAGGCTGAGGCAGAAGAATCATTTGAACCCCGGAG
GTGGAGGTTGCAGTGAGCCGACATTGTGCCGCTTCATTCCAGCCTGGGCAACAGAGTGAAACTCTTGTCTCAAAAGTAAAAAAATAATAA
TGTTTAAAAATATTTCAATGTGGAGACAAGCTCAAAATGAAATTAGACACATTCCATTACCCAGGTAAAAGAAGGGGAAGCCTGACTTGA
TAGTAGTATTCAGGAAAAAAGAGTTGGCAGTTTTATTTGGCCAAATTCCAATATCAGCTCATGGTACAGCACACCGGGGGAGGGGGACGG
GAGGCGAGAACTAAGGCTTTTTAAGAATGTGTTGATGGAAGTATGTGCCTAGATCAAAAGAATAATCCCCCCGGACTCCAGTGTAAGATC
AATTACTGTTGGAATATTGTGTTCCTTTCTAGATATCACATTTTAAGCAGACTTTGGCCAAGTAGTACAGTGTTTGCAGGAGCAGTAACA
AGATGGTGATAACTTTGAAAATACTTCTCAAAAGAAAAATAAAAAAGAATTAGGGAAGTTCAGTCTGGAGATAATTCAGAAATACAGATG
ATAATTGTTTTCAAATTCTTGAAGGAAATGGGAGAGAGAATAGGCTAATTCTGTATTGCTTCAGAAACCAAATGGAAACAATTAAATTCC
ATTAGAGAAACGGTTGGAAAATATGAGGAGGATTTAGTTCAGTACGAGGAAGCTGTTTCTAATACTTTTTGTTGGTTAAAAATACATTCC
GCTGCTGTGGAAAGCCTGTAGCTGCCAGGAGTGTTACAGAGGGCATTCCTCCCTTGAGTTGACATTTGTGCCAAACCGGCTTTTAGGGCT
TCTCCAGCTTTTAAGATGCGATAATGATAAGATGATCATCGGGAAAACATCCCTCAGATGAAACGTTCACAGGCTGGCTCTGAAAACTGG
CATTCAGATGATTGCGGCTCCCCCATACTGTAGGAATATTGTTTATGGCTTAAGGTTGCCTCGCTCCTCATCTGTAATCAGTGAAAGTTT
ATCCAGAGGTTAATTACCGGTTTTCTGGTGGGTATCTGGGAACTGAGGATGGGAGATTAACTGTTGTATATGACCATAGTAAAGCAAAAG
ACTGTTAGAGAATGAGTAAACGTTCGTTTTCCTCCCTACAGAATTTACAGTTACTCTCTGTCCATTCCACTCACTACTGTCTTCATCACA
CACACAGAGGCAAACGTCTGATTCAGATAGCCAGGTGTGCCATGCATGCACTCCACCATATTGTGATCTCTTCGAGGCTTGTTTCTGTCC

>68346_68346_1_PPWD1-NLN_PPWD1_chr5_64875440_ENST00000261308_NLN_chr5_65076006_ENST00000380985_length(amino acids)=979AA_BP=1
MCRAFSDDANNMAAESGSDFQQRRRRRRDPEEPEKTELSERELAVAVAVSQENDEENEERWVGPLPVEATLAKKRKVLEFERVYLDNLPS
ASMYERSYMHRDVITHVVCTKTDFIITASHDGHVKFWKKIEEGIEFVKHFRSHLGVIESIAVSSEGALFCSVGDDKAMKVFDVVNFDMIN
MLKLGYFPGQCEWIYCPGDAISSVAASEKSTGKIFIYDGRGDNQPLHIFDKLHTSPLTQIRLNPVYKAVVSSDKSGMIEYWTGPPHEYKF
PKNVNWEYKTDTDLYEFAKCKAYPTSVCFSPDGKKIATIGSDRKVRIFRFVTGKLMRVFDESLSMFTELQQMRQQLPDMEFGRRMAVERE
LEKVDAVRLINIVFDETGHFVLYGTMLGIKVINVETNRCVRILGKQENIRVMQLALFQGIAKKHRAATTIEMKASENPVLQNIQADPTIV
CTSFKKNRFYMEIKSMKKRMSELCIDFNKNLNEDDTFLVFSKAELGALPDDFIDSLEKTDDDKYKITLKYPHYFPVMKKCCIPETRRRME
MAFNTRCKEENTIILQQLLPLRTKVAKLLGYSTHADFVLEMNTAKSTSRVTAFLDDLSQKLKPLGEAEREFILNLKKKECKDRGFEYDGK
INAWDLYYYMTQTEELKYSIDQEFLKEYFPIEVVTEGLLNTYQELLGLSFEQMTDAHVWNKSVTLYTVKDKATGEVLGQFYLDLYPREGK
YNHAACFGLQPGCLLPDGSRMMAVAALVVNFSQPVAGRPSLLRHDEVRTYFHEFGHVMHQICAQTDFARFSGTNVETDFVEVPSQMLENW
VWDVDSLRRLSKHYKDGSPIADDLLEKLVASRLVNTGLLTLRQIVLSKVDQSLHTNTSLDAASEYAKYCSEILGVAATPGTNMPATFGHL

--------------------------------------------------------------
>68346_68346_2_PPWD1-NLN_PPWD1_chr5_64875440_ENST00000261308_NLN_chr5_65076006_ENST00000502464_length(transcript)=9347nt_BP=1422nt
AGAAGACTGCGCCGCTGCTTTGGGATTGGTAGCTGAGTTTTGTGTCGCGCCTTTTCTGACGATGCGAACAACATGGCGGCGGAAAGTGGT
AGCGATTTTCAGCAGAGACGTAGAAGGCGCCGGGACCCGGAGGAACCGGAAAAAACAGAACTCAGCGAAAGAGAGCTGGCAGTAGCAGTG
GCGGTGTCCCAGGAGAACGATGAGGAGAACGAAGAGCGCTGGGTTGGACCTTTACCTGTGGAGGCAACACTGGCCAAGAAGAGGAAAGTC
TTAGAGTTTGAAAGAGTCTATCTTGATAATCTCCCCAGTGCATCCATGTATGAGCGCAGTTACATGCATAGAGATGTTATCACCCATGTG
GTATGCACCAAAACAGATTTTATTATTACTGCCAGTCATGATGGACATGTCAAGTTCTGGAAAAAAATAGAAGAGGGAATTGAATTTGTT
AAACATTTTCGTAGTCACCTGGGAGTTATTGAGAGTATTGCAGTTAGCTCTGAGGGAGCATTGTTCTGTTCTGTGGGTGATGATAAAGCA
ATGAAGGTGTTTGATGTAGTGAACTTTGACATGATCAACATGCTGAAACTTGGCTATTTTCCTGGACAGTGTGAGTGGATCTATTGCCCA
GGGGATGCAATTTCTTCAGTTGCTGCTTCCGAAAAGAGTACAGGAAAAATTTTCATTTATGATGGCCGAGGAGATAACCAGCCACTTCAT
ATTTTTGACAAACTCCATACATCACCTCTTACTCAGATACGGCTAAACCCAGTTTACAAAGCAGTAGTGTCTTCTGACAAATCTGGGATG
ATTGAATACTGGACTGGGCCTCCTCATGAATATAAATTCCCCAAAAATGTGAACTGGGAATATAAAACTGACACTGATTTATATGAATTT
GCCAAGTGTAAGGCTTATCCAACCAGCGTATGTTTTTCACCAGATGGGAAGAAAATAGCTACTATTGGTTCTGATAGAAAAGTTAGAATT
TTCAGATTTGTAACTGGAAAACTCATGAGAGTCTTTGATGAATCACTAAGCATGTTTACTGAACTGCAACAGATGAGGCAACAGTTACCA
GACATGGAATTTGGCCGACGAATGGCTGTAGAACGTGAGTTGGAGAAGGTTGATGCTGTAAGATTAATTAATATAGTTTTTGATGAAACT
GGACACTTCGTGCTGTATGGAACAATGCTGGGCATTAAAGTTATAAATGTAGAGACAAACCGGTGTGTGCGGATTTTAGGCAAACAAGAA
AATATTAGAGTGATGCAATTGGCTTTGTTCCAGGGGATAGCCAAAAAGCATCGTGCTGCAACTACTATAGAAATGAAAGCTTCTGAAAAT
CCTGTTCTTCAGAATATTCAAGCTGACCCAACAATAGTCTGTACATCATTCAAAAAGAATAGATTTTATATGGAAATCAAATCAATGAAG
AAAAGAATGAGTGAGCTATGTATTGATTTTAACAAAAACCTCAATGAGGATGATACCTTCCTTGTATTTTCCAAGGCTGAACTTGGTGCT
CTTCCTGATGATTTCATTGACAGTTTAGAAAAGACAGATGATGACAAGTATAAAATTACCTTAAAATATCCACACTATTTCCCTGTCATG
AAGAAATGTTGTATCCCTGAAACCAGAAGAAGGATGGAAATGGCTTTTAATACAAGGTGCAAAGAGGAAAACACCATAATTTTGCAGCAG
CTACTCCCACTGCGAACCAAGGTGGCCAAACTACTCGGTTATAGCACACATGCTGACTTCGTCCTTGAAATGAACACTGCAAAGAGCACA
AGCCGCGTAACAGCCTTTCTAGATGATTTAAGCCAGAAGTTAAAACCCTTGGGTGAAGCAGAACGAGAGTTTATTTTGAATTTGAAGAAA
AAGGAATGCAAAGACAGGGGTTTTGAATATGATGGGAAAATCAATGCCTGGGATCTATATTACTACATGACTCAGACAGAGGAACTCAAG
TATTCCATAGACCAAGAGTTCCTCAAGGAATACTTCCCAATTGAGGTGGTCACTGAAGGCTTGCTGAACACCTACCAGGAGTTGTTGGGA
CTTTCATTTGAACAAATGACAGATGCTCATGTTTGGAACAAGAGTGTTACACTTTATACTGTGAAGGATAAAGCTACAGGAGAAGTATTG
GGACAGTTCTATTTGGACCTCTATCCAAGGGAAGGAAAATACAATCATGCGGCCTGCTTCGGTCTCCAGCCTGGCTGCCTTCTGCCTGAT
GGAAGCCGGATGATGGCAGTGGCTGCCCTCGTGGTGAACTTCTCACAGCCAGTGGCAGGTCGTCCCTCTCTCCTGAGACACGACGAGGTG
AGGACTTACTTTCATGAGTTTGGTCACGTGATGCATCAGATTTGTGCACAGACTGATTTTGCACGATTTAGCGGAACAAATGTGGAAACT
GACTTTGTAGAGGTGCCATCGCAAATGCTTGAAAATTGGGTGTGGGACGTCGATTCCCTCCGAAGATTGTCAAAACATTATAAAGATGGA
AGCCCTATTGCAGACGATCTGCTTGAAAAACTTGTTGCTTCTAGGCTGGTCAACACAGGTCTTCTGACCCTGCGCCAGATTGTTTTGAGC
AAAGTTGATCAGTCTCTTCATACCAACACATCGCTGGATGCTGCAAGTGAATATGCCAAATACTGCTCAGAAATATTAGGAGTTGCAGCT
ACTCCAGGCACAAATATGCCAGCTACCTTTGGACATTTGGCAGGGGGATACGATGGCCAATATTATGGATATCTTTGGAGTGAAGTATTT
TCCATGGATATGTTTTACAGCTGTTTTAAAAAAGAAGGGATAATGAATCCAGAGGTTGGAATGAAATACAGAAACCTAATCCTGAAACCT
GGGGGATCTCTGGACGGCATGGACATGCTCCACAATTTCTTGAAACGTGAGCCAAACCAAAAAGCGTTCCTAATGAGTAGAGGCCTGCAT
GCTCCGTGAACTGGGGATCTTTGGTAGCCGTCCATGTCTGGAGGACAAGTCGACATCACCATGTGTTACTGGCCTGGAAACTGAAGGGAG
TTTTGCAAGTGAAAATTTAGATTTCTATTGACATCCTTTTGTTTTCTAATTTTAAAAATTATAAAGATGTAAATGGAATTATAAATACTG
TGACCTAAGAAAAGACCCACTAGAAAGTAATTGTACTATAAAATTTCATAAAACTGGATTTGATTTCTTTTTATGAAAGTTTCATATGAA
TGTAACTTGATTTTTTACTATTATAATCTAGATAATATGATATAAGAGGGCTAAGAATTTTTAAATTGAATCATATATATGATATAATTT
GATCCTTCTTGTATCTTGAAGTTTTGTACTTGGGATTTCTGGACTGATAAATGAATCATCACATTCTTCTGGTAAATATTTTCTTGGAGC
TCTGTGTCAACTTTGATCCTTTGTCTCCCAGGAAGGTGTGACCTCTCCTTTGCCTGCATACCTCAAGGCCAGGGGAATATGCCTCAGTGA
TGCATTTATCTTTGTATATCAGGCCGCATGATTCCCAACTTTCTGCCACACTTAAATTACGTTCCTCCATTTCAGTTTTGTCTTTTCTGT
CTAAAGTTCAGTCAAAGAGTATCAAAAAATTATGTTTCAGCTAGACTGGTGTAATGTATAAGTTTTTGTATCTTGTATTAGAGGATTTCG
TAGCTTTTATTAGAGGCTCATTTCCACCTCAGCATACAAGATCGTTAGTCTTTTGGCATGTGTGCCAATTAGAATACTAAAGCAAGTCCA
AGCACATTTTTCTCTTCTCACGTTTCTAATAAGTGTTAGGGACTTTGCCTCTTTTACTTACCACGTCCCCAAAAGTGTCAGGTAGACATG
TCACAAATGGCTCTGTAGAGAGCCATGGGAAGAGAGAGGAGGTGGATGTGGAACATAAAGGGTTCAGAAACTCCAGAAGAGGAGTGGGTT
TTGGATAGAAGCATTTGAGGACAGCTGCTCCAAAGCCTTATGTGTATGATGAAACTTAACCACGGGGAAGAGACTCTTCAGTAGCCTGTT
CTGTCTGGTGATTTTTATTTTAAGTGAACCTTTGGATCTATCTTTAACTCTCTTTATTGTGAGTCTAAATTCCAATTCTGCAGCAGATCA
GTAAACTCACAGTATTTTTCCTGTGGAAATCTATTCAATAAGGAAACCAAGACAGGATAATAAAATTTAAAAAAAAAACAACTTTGAATT
CCCCTGCCTAGGTCTTCCAGTTGTTTTCCAGCGCATACCTCAGGTATGACTTTGCTAGCCGGGGACAAAATTAGCACCTTCCGATTCTCT
AGTCCAAATGAACTTTGTGCTAAATAAAAAATTATTATACTACATAATAAAGTTACAGATAGCAGGAAATGCAAGAGCTAGGAGATTCCT
AGATTATATCTGCCAAGCAAATACCTTAAACATCCACCTGAAATCCTACTACCCCCTCTTCTGAGATAATTTGCCCAGCCCTTCTCTTCC
CACACACTCACTCAATGTCACCCCCTTCTAATCCCCAAAACTGTTTTTGTGGTCTTTGTAGCCTATAGTAGTTTTCTCACATCTTTCCCC
CTAGACTTTTCTGTTTTTCAGTTTCAGACAAAAAAACTCTTCAGCTTTTTCCAGTGTGTCTCCTTAACAGTAACTTTACCACTTGAAATC
TTATTTCATAGAAAAACTAAATTGGTGTGGAAAGGCTGCACACAATAAAGTTATATTATTATCCATGAAAATGAACTCATATTTCTTTCA
TACTTTAACGTTAAAACCGAAATGCATGAGAGCAAAAGCACCATGGTGTTCTTTCTATTTAGGGCCTACCTCTAATATTTAAAATCTACC
AAAGAGCAGTCACAAAATTAAAACTCAGCCCGGGCGCAGTGGCTCATGCCTGTAATCCCAGCACTTTGGGAGGCCAAGGCAGGAGGATCA
CCTGAGGTCAGAGTTCAAGACCAGCATGGTCAACATGGTGAAACCCTGTCTCTACAAAAATACAAAAAGCTGGGCATGATGTTGGGTTCC
TGTAGTCCCAGCTACTTAGGAGGCTGAGGCAGGAGAATAGCTTGAACCCGGGAGGTGGAGGTTGCAGTGAGCTGAGATCATGCCATTGCA
CTCCAGCCTGGACGACAGAGTGAGATTCAGTCTCAAAAAAAATTAATACTCAAAGAATTATCTAGCATAATTTAAAAGAAAGGACTTTTT
AAAAATTCTCTAGCATAATTCAAAAGAAAGGACTTAACTTTTTTTTTTTTAGTGTGGTCATCCGTCTAGTTGTTCTTTTTTTCCAGATCA
GAGCAGAGAATATCACTGACATGCTTGAAATGGTGGATAACTATGTAAATTGTAATTGGACAAATGTACACTTTAGATTTATGGACTGAG
CCACATATAATAAGGTCTCTCCTGGTAATTGATCCAGGGGATTTAGGCCTCTTTCGGGTTTTTTGTTTTTTTTTTAGGCATTGTTATGTT
GTGAAGGATAAAATCTTCAACATCTTATGCAAATGGATAGTAGGCATGATCCTAAAGGTTTAGTTTTACGATGCTGCAGAGAAGAGAAAT
GTCTTGACGTTTTGCCACCTGATGTAGACTTTGTCCCCCTCTAGTATAAATGTTGCATGTTACCTAGATAAACAACTAAAAATTGCCTTG
AGTTATCACCTGAGCTACTTATGCCAAGGTCTTGCCTTTCTAAAGCTAATAAGGTGAGAGGTGGATATCTGTAGCTCTTCGGATGAAAAA
TTGCATTGTGGGAGATACCAAAATTGAGGAAATAGCTCTTCAAAGAAAAATTACTGATATGATCATTGTACTTGTAAATGCCTTAAGTAG
CAGGCAGTGACTCAATTTTCTACTTTACCATTTTACCTTTAGCTTTTATGTATGAATTATAGGTCTGTGGAGATTCTGCCTCCCCACTAG
GCCAGTGTGTGTTTACCATTTATTCATTTTCTATCATACACAGGTGGATTAAAATTTACATTAAAATTTACATTAAAATACCATCATACT
TCAGGCTTCTATAACAAAATATCAGACTGGGTGGCTTCAAAAGCAGACATTTCTTACAGTTCTGGAAGCTGGGAAGTCCCACAATCCACA
TGCTGGTAAATTTGGTTCGTGGTGAGGCCCCTCTTCCTCTTTTACTGACCACATCCCCAAAAGTGTCAGGTAGACATGTTACAAATAGCT
CTGTAGAGAGCCATGGGAAGAGACAGGAGGCAGATGTGGAACATAAAGGGTTTAGAAACTTCTGCAGGCAGCAGTGGCAGGGAGCAAGCC
CTAGAGTGTCTCTTTTTACGAGAGCAGGAATCCCATCATGAGAGTTCCTTCCTCATGACTTTATCTAAACCCAGTCACCCCCAACAAAGG
CCCCACCCCCTAACCCCATCACATTGGCTGTTACGGCTTCAATGTAGGGGATGGGGCACAAACATTCAGTCCATAACGAATACTGATTCC
TCAAATAGGGTTTAAACATAGTTAACTGAGCCCCCAAAGAATGTTAAAAGAGAAAATCCATTTTATTTGAATAGATGCAGTGACCACAGC
TTCTTCCCTCAAATCAACACATTACAGTTAGATGTCTCCCATCTGAAATTGGATAGCCCACTGAAATTGAACATGCCTTCTCTTATAAAT
GTGTGGTGAGAATAAAAGCAACAAAGAAATGAATGTGGTGGCTCACACCTGTAATCCTAACACTTTGGAAGGTTGAGGCAGGAGGATCCT
TTGTGCTCAAGAGTTTGAGACCAGCCTGAGCAACACAGTGAGACCCTGTCTCTACAAAAACTAAAAAAATTAGCTAGGGATGGTGGCACA
TGCCTGTAGTCCCAGCTACTTGGGAGGCTGAGGTGGGAGGATTGCTTGAGCCCAAGAAGGTCAAGGCTGCCATGAGCCATAATCACGCCA
CTGCACTCCAGCCTGGGTGACAGAGACCCTGTCTTAAAATAAAATAAAAAAAAAAGGAAAAGGAAAGACATACATACCCTCAGTTCTTCG
AAAAACAGTCAACGTCCAAAAAGTTTATTTTTTGAGTCACCTTTAATAGAGAAATTTCCCACTGGAAACAGATCCACCTAAGTGATTATC
TAGTATCAGCTGTATCAAGGCAAAAGGTAAAGGTTATAAGATGTAAATATTAGACCAAAATAGCCTTTTTTAACAAACACAATAATGCTG
TACGTCTGTAACAAAACAAAATTTGAAAAATTGAGGTAATGTACACAGCGATGCACACACCCCCACACCACACCGTGATTCCTGAGTTTT
GATTTGGTTGAATTCACCTTGTAGTTCCCTTTCCTGAGAAAATACAGGTTCAACACATCTAGTCCACGATGTACGTACAAGGGGAAGGGG
TGAACAGGAAATAGACTCCCTTATTCTGCTCACATGAGCTGGAACCTGTACTAGCTGCATATTTCATAGACCCCAGAGGCTCACCTCAAT
TGTACTCCTATGATAAAATGTCTCTAGCATTTGTCATGAGAGAAACTGGCTAGAAATAGTTTGTTCATTGCGTCCAGCAAGACACGCATT
GCTGTTGATATCTTTGTGGCTAAGATGGAGAATGTGACTGGATAATAGTTATCCAGGTGGATTACTAGCTATTGAAACAGTCTGAGATAG
TTGCATGATGATTAACGTTAAACTGGGAGTAATTTCAAGTCATTTGGCTAAAAATGAAAAAAAAGTCCCATAAAAAGGTATCAAATGTAC
AGATAATAGGGCTGGAATTATTAAGTATGATGATGTTATTAACATCTAAAATTATTTTGGCCGGGCAAGGTGGGTCACGCCTGTAATCTC
AGCACTTTGGGATGCCAAGATGGGTGGATCACCTGAGTTCAGGAGTTCAAGACCAGCTTGGCCAACATGGCGAAACCCGTCTCTACTAAA
GAATACAAAAATTAGCCAGGTGTTGTGGCACATGCCTGTACTCCCAGCTACTCAGGAGGCTGAGGCAGAAGAATCATTTGAACCCCGGAG
GTGGAGGTTGCAGTGAGCCGACATTGTGCCGCTTCATTCCAGCCTGGGCAACAGAGTGAAACTCTTGTCTCAAAAGTAAAAAAATAATAA
TGTTTAAAAATATTTCAATGTGGAGACAAGCTCAAAATGAAATTAGACACATTCCATTACCCAGGTAAAAGAAGGGGAAGCCTGACTTGA
TAGTAGTATTCAGGAAAAAAGAGTTGGCAGTTTTATTTGGCCAAATTCCAATATCAGCTCATGGTACAGCACACCGGGGGAGGGGGACGG
GAGGCGAGAACTAAGGCTTTTTAAGAATGTGTTGATGGAAGTATGTGCCTAGATCAAAAGAATAATCCCCCCGGACTCCAGTGTAAGATC
AATTACTGTTGGAATATTGTGTTCCTTTCTAGATATCACATTTTAAGCAGACTTTGGCCAAGTAGTACAGTGTTTGCAGGAGCAGTAACA
AGATGGTGATAACTTTGAAAATACTTCTCAAAAGAAAAATAAAAAAGAATTAGGGAAGTTCAGTCTGGAGATAATTCAGAAATACAGATG
ATAATTGTTTTCAAATTCTTGAAGGAAATGGGAGAGAGAATAGGCTAATTCTGTATTGCTTCAGAAACCAAATGGAAACAATTAAATTCC
ATTAGAGAAACGGTTGGAAAATATGAGGAGGATTTAGTTCAGTACGAGGAAGCTGTTTCTAATACTTTTTGTTGGTTAAAAATACATTCC
GCTGCTGTGGAAAGCCTGTAGCTGCCAGGAGTGTTACAGAGGGCATTCCTCCCTTGAGTTGACATTTGTGCCAAACCGGCTTTTAGGGCT
TCTCCAGCTTTTAAGATGCGATAATGATAAGATGATCATCGGGAAAACATCCCTCAGATGAAACGTTCACAGGCTGGCTCTGAAAACTGG
CATTCAGATGATTGCGGCTCCCCCATACTGTAGGAATATTGTTTATGGCTTAAGGTTGCCTCGCTCCTCATCTGTAATCAGTGAAAGTTT
ATCCAGAGGTTAATTACCGGTTTTCTGGTGGGTATCTGGGAACTGAGGATGGGAGATTAACTGTTGTATATGACCATAGTAAAGCAAAAG
ACTGTTAGAGAATGAGTAAACGTTCGTTTTCCTCCCTACAGAATTTACAGTTACTCTCTGTCCATTCCACTCACTACTGTCTTCATCACA
CACACAGAGGCAAACGTCTGATTCAGATAGCCAGGTGTGCCATGCATGCACTCCACCATATTGTGATCTCTTCGAGGCTTGTTTCTGTCC

>68346_68346_2_PPWD1-NLN_PPWD1_chr5_64875440_ENST00000261308_NLN_chr5_65076006_ENST00000502464_length(amino acids)=979AA_BP=1
MCRAFSDDANNMAAESGSDFQQRRRRRRDPEEPEKTELSERELAVAVAVSQENDEENEERWVGPLPVEATLAKKRKVLEFERVYLDNLPS
ASMYERSYMHRDVITHVVCTKTDFIITASHDGHVKFWKKIEEGIEFVKHFRSHLGVIESIAVSSEGALFCSVGDDKAMKVFDVVNFDMIN
MLKLGYFPGQCEWIYCPGDAISSVAASEKSTGKIFIYDGRGDNQPLHIFDKLHTSPLTQIRLNPVYKAVVSSDKSGMIEYWTGPPHEYKF
PKNVNWEYKTDTDLYEFAKCKAYPTSVCFSPDGKKIATIGSDRKVRIFRFVTGKLMRVFDESLSMFTELQQMRQQLPDMEFGRRMAVERE
LEKVDAVRLINIVFDETGHFVLYGTMLGIKVINVETNRCVRILGKQENIRVMQLALFQGIAKKHRAATTIEMKASENPVLQNIQADPTIV
CTSFKKNRFYMEIKSMKKRMSELCIDFNKNLNEDDTFLVFSKAELGALPDDFIDSLEKTDDDKYKITLKYPHYFPVMKKCCIPETRRRME
MAFNTRCKEENTIILQQLLPLRTKVAKLLGYSTHADFVLEMNTAKSTSRVTAFLDDLSQKLKPLGEAEREFILNLKKKECKDRGFEYDGK
INAWDLYYYMTQTEELKYSIDQEFLKEYFPIEVVTEGLLNTYQELLGLSFEQMTDAHVWNKSVTLYTVKDKATGEVLGQFYLDLYPREGK
YNHAACFGLQPGCLLPDGSRMMAVAALVVNFSQPVAGRPSLLRHDEVRTYFHEFGHVMHQICAQTDFARFSGTNVETDFVEVPSQMLENW
VWDVDSLRRLSKHYKDGSPIADDLLEKLVASRLVNTGLLTLRQIVLSKVDQSLHTNTSLDAASEYAKYCSEILGVAATPGTNMPATFGHL

--------------------------------------------------------------
>68346_68346_3_PPWD1-NLN_PPWD1_chr5_64875440_ENST00000535264_NLN_chr5_65076006_ENST00000380985_length(transcript)=9327nt_BP=1402nt
GACGATGCGAACAACATGGCGGCGGAAAGTGGTAGCGATTTTCAGCAGAGACGTAGAAGGCGCCGGGACCCGGAGGAACCGGAAAAAACA
GAACTCAGCGAAAGAGAGCTGGCAGTAGCAGTGGCGGTGTCCCAGGAGAACGATGAGGAGAACGAAGAGCGCTGGGTTGGACCTTTACCT
GTGGAGGCAACACTGGCCAAGAAGAGGAAAGCAGCCACATGAAGTTGGAATTTCGAACTCTTATTTAGTCTTAGAGTTTGAAAGAGTCTA
TCTTGATAATCTCCCCAGTGCATCCATGTATGAGCGCAGTTACATGCATAGAGATGTTATCACCCATGTGGTATGCACCAAAACAGATTT
TATTATTACTGCCAGTCATGATGGACATGTCAAGTTCTGGAAAAAAATAGAAGAGGGAATTGAATTTGTTAAACATTTTCGTAGTCACCT
GGGAGTTATTGAGAGTATTGCAGTTAGCTCTGAGGGAGCATTGTTCTGTTCTGTGGGTGATGATAAAGCAATGAAGGTGTTTGATGTAGT
GAACTTTGACATGATCAACATGCTGAAACTTGGCTATTTTCCTGGACAGTGTGAGTGGATCTATTGCCCAGGGGATGCAATTTCTTCAGT
TGCTGCTTCCGAAAAGAGTACAGGAAAAATTTTCATTTATGATGGCCGAGGAGATAACCAGCCACTTCATATTTTTGACAAACTCCATAC
ATCACCTCTTACTCAGATACGGCTAAACCCAGTTTACAAAGCAGTAGTGTCTTCTGACAAATCTGGGATGATTGAATACTGGACTGGGCC
TCCTCATGAATATAAATTCCCCAAAAATGTGAACTGGGAATATAAAACTGACACTGATTTATATGAATTTGCCAAGTGTAAGGCTTATCC
AACCAGCGTATGTTTTTCACCAGATGGGAAGAAAATAGCTACTATTGGTTCTGATAGAAAAGTTAGAATTTTCAGATTTGTAACTGGAAA
ACTCATGAGAGTCTTTGATGAATCACTAAGCATGTTTACTGAACTGCAACAGATGAGGCAACAGTTACCAGACATGGAATTTGGCCGACG
AATGGCTGTAGAACGTGAGTTGGAGAAGGTTGATGCTGTAAGATTAATTAATATAGTTTTTGATGAAACTGGACACTTCGTGCTGTATGG
AACAATGCTGGGCATTAAAGTTATAAATGTAGAGACAAACCGGTGTGTGCGGATTTTAGGCAAACAAGAAAATATTAGAGTGATGCAATT
GGCTTTGTTCCAGGGGATAGCCAAAAAGCATCGTGCTGCAACTACTATAGAAATGAAAGCTTCTGAAAATCCTGTTCTTCAGAATATTCA
AGCTGACCCAACAATAGTCTGTACATCATTCAAAAAGAATAGATTTTATATGGAAATCAAATCAATGAAGAAAAGAATGAGTGAGCTATG
TATTGATTTTAACAAAAACCTCAATGAGGATGATACCTTCCTTGTATTTTCCAAGGCTGAACTTGGTGCTCTTCCTGATGATTTCATTGA
CAGTTTAGAAAAGACAGATGATGACAAGTATAAAATTACCTTAAAATATCCACACTATTTCCCTGTCATGAAGAAATGTTGTATCCCTGA
AACCAGAAGAAGGATGGAAATGGCTTTTAATACAAGGTGCAAAGAGGAAAACACCATAATTTTGCAGCAGCTACTCCCACTGCGAACCAA
GGTGGCCAAACTACTCGGTTATAGCACACATGCTGACTTCGTCCTTGAAATGAACACTGCAAAGAGCACAAGCCGCGTAACAGCCTTTCT
AGATGATTTAAGCCAGAAGTTAAAACCCTTGGGTGAAGCAGAACGAGAGTTTATTTTGAATTTGAAGAAAAAGGAATGCAAAGACAGGGG
TTTTGAATATGATGGGAAAATCAATGCCTGGGATCTATATTACTACATGACTCAGACAGAGGAACTCAAGTATTCCATAGACCAAGAGTT
CCTCAAGGAATACTTCCCAATTGAGGTGGTCACTGAAGGCTTGCTGAACACCTACCAGGAGTTGTTGGGACTTTCATTTGAACAAATGAC
AGATGCTCATGTTTGGAACAAGAGTGTTACACTTTATACTGTGAAGGATAAAGCTACAGGAGAAGTATTGGGACAGTTCTATTTGGACCT
CTATCCAAGGGAAGGAAAATACAATCATGCGGCCTGCTTCGGTCTCCAGCCTGGCTGCCTTCTGCCTGATGGAAGCCGGATGATGGCAGT
GGCTGCCCTCGTGGTGAACTTCTCACAGCCAGTGGCAGGTCGTCCCTCTCTCCTGAGACACGACGAGGTGAGGACTTACTTTCATGAGTT
TGGTCACGTGATGCATCAGATTTGTGCACAGACTGATTTTGCACGATTTAGCGGAACAAATGTGGAAACTGACTTTGTAGAGGTGCCATC
GCAAATGCTTGAAAATTGGGTGTGGGACGTCGATTCCCTCCGAAGATTGTCAAAACATTATAAAGATGGAAGCCCTATTGCAGACGATCT
GCTTGAAAAACTTGTTGCTTCTAGGCTGGTCAACACAGGTCTTCTGACCCTGCGCCAGATTGTTTTGAGCAAAGTTGATCAGTCTCTTCA
TACCAACACATCGCTGGATGCTGCAAGTGAATATGCCAAATACTGCTCAGAAATATTAGGAGTTGCAGCTACTCCAGGCACAAATATGCC
AGCTACCTTTGGACATTTGGCAGGGGGATACGATGGCCAATATTATGGATATCTTTGGAGTGAAGTATTTTCCATGGATATGTTTTACAG
CTGTTTTAAAAAAGAAGGGATAATGAATCCAGAGGTTGGAATGAAATACAGAAACCTAATCCTGAAACCTGGGGGATCTCTGGACGGCAT
GGACATGCTCCACAATTTCTTGAAACGTGAGCCAAACCAAAAAGCGTTCCTAATGAGTAGAGGCCTGCATGCTCCGTGAACTGGGGATCT
TTGGTAGCCGTCCATGTCTGGAGGACAAGTCGACATCACCATGTGTTACTGGCCTGGAAACTGAAGGGAGTTTTGCAAGTGAAAATTTAG
ATTTCTATTGACATCCTTTTGTTTTCTAATTTTAAAAATTATAAAGATGTAAATGGAATTATAAATACTGTGACCTAAGAAAAGACCCAC
TAGAAAGTAATTGTACTATAAAATTTCATAAAACTGGATTTGATTTCTTTTTATGAAAGTTTCATATGAATGTAACTTGATTTTTTACTA
TTATAATCTAGATAATATGATATAAGAGGGCTAAGAATTTTTAAATTGAATCATATATATGATATAATTTGATCCTTCTTGTATCTTGAA
GTTTTGTACTTGGGATTTCTGGACTGATAAATGAATCATCACATTCTTCTGGTAAATATTTTCTTGGAGCTCTGTGTCAACTTTGATCCT
TTGTCTCCCAGGAAGGTGTGACCTCTCCTTTGCCTGCATACCTCAAGGCCAGGGGAATATGCCTCAGTGATGCATTTATCTTTGTATATC
AGGCCGCATGATTCCCAACTTTCTGCCACACTTAAATTACGTTCCTCCATTTCAGTTTTGTCTTTTCTGTCTAAAGTTCAGTCAAAGAGT
ATCAAAAAATTATGTTTCAGCTAGACTGGTGTAATGTATAAGTTTTTGTATCTTGTATTAGAGGATTTCGTAGCTTTTATTAGAGGCTCA
TTTCCACCTCAGCATACAAGATCGTTAGTCTTTTGGCATGTGTGCCAATTAGAATACTAAAGCAAGTCCAAGCACATTTTTCTCTTCTCA
CGTTTCTAATAAGTGTTAGGGACTTTGCCTCTTTTACTTACCACGTCCCCAAAAGTGTCAGGTAGACATGTCACAAATGGCTCTGTAGAG
AGCCATGGGAAGAGAGAGGAGGTGGATGTGGAACATAAAGGGTTCAGAAACTCCAGAAGAGGAGTGGGTTTTGGATAGAAGCATTTGAGG
ACAGCTGCTCCAAAGCCTTATGTGTATGATGAAACTTAACCACGGGGAAGAGACTCTTCAGTAGCCTGTTCTGTCTGGTGATTTTTATTT
TAAGTGAACCTTTGGATCTATCTTTAACTCTCTTTATTGTGAGTCTAAATTCCAATTCTGCAGCAGATCAGTAAACTCACAGTATTTTTC
CTGTGGAAATCTATTCAATAAGGAAACCAAGACAGGATAATAAAATTTAAAAAAAAAACAACTTTGAATTCCCCTGCCTAGGTCTTCCAG
TTGTTTTCCAGCGCATACCTCAGGTATGACTTTGCTAGCCGGGGACAAAATTAGCACCTTCCGATTCTCTAGTCCAAATGAACTTTGTGC
TAAATAAAAAATTATTATACTACATAATAAAGTTACAGATAGCAGGAAATGCAAGAGCTAGGAGATTCCTAGATTATATCTGCCAAGCAA
ATACCTTAAACATCCACCTGAAATCCTACTACCCCCTCTTCTGAGATAATTTGCCCAGCCCTTCTCTTCCCACACACTCACTCAATGTCA
CCCCCTTCTAATCCCCAAAACTGTTTTTGTGGTCTTTGTAGCCTATAGTAGTTTTCTCACATCTTTCCCCCTAGACTTTTCTGTTTTTCA
GTTTCAGACAAAAAAACTCTTCAGCTTTTTCCAGTGTGTCTCCTTAACAGTAACTTTACCACTTGAAATCTTATTTCATAGAAAAACTAA
ATTGGTGTGGAAAGGCTGCACACAATAAAGTTATATTATTATCCATGAAAATGAACTCATATTTCTTTCATACTTTAACGTTAAAACCGA
AATGCATGAGAGCAAAAGCACCATGGTGTTCTTTCTATTTAGGGCCTACCTCTAATATTTAAAATCTACCAAAGAGCAGTCACAAAATTA
AAACTCAGCCCGGGCGCAGTGGCTCATGCCTGTAATCCCAGCACTTTGGGAGGCCAAGGCAGGAGGATCACCTGAGGTCAGAGTTCAAGA
CCAGCATGGTCAACATGGTGAAACCCTGTCTCTACAAAAATACAAAAAGCTGGGCATGATGTTGGGTTCCTGTAGTCCCAGCTACTTAGG
AGGCTGAGGCAGGAGAATAGCTTGAACCCGGGAGGTGGAGGTTGCAGTGAGCTGAGATCATGCCATTGCACTCCAGCCTGGACGACAGAG
TGAGATTCAGTCTCAAAAAAAATTAATACTCAAAGAATTATCTAGCATAATTTAAAAGAAAGGACTTTTTAAAAATTCTCTAGCATAATT
CAAAAGAAAGGACTTAACTTTTTTTTTTTTAGTGTGGTCATCCGTCTAGTTGTTCTTTTTTTCCAGATCAGAGCAGAGAATATCACTGAC
ATGCTTGAAATGGTGGATAACTATGTAAATTGTAATTGGACAAATGTACACTTTAGATTTATGGACTGAGCCACATATAATAAGGTCTCT
CCTGGTAATTGATCCAGGGGATTTAGGCCTCTTTCGGGTTTTTTGTTTTTTTTTTAGGCATTGTTATGTTGTGAAGGATAAAATCTTCAA
CATCTTATGCAAATGGATAGTAGGCATGATCCTAAAGGTTTAGTTTTACGATGCTGCAGAGAAGAGAAATGTCTTGACGTTTTGCCACCT
GATGTAGACTTTGTCCCCCTCTAGTATAAATGTTGCATGTTACCTAGATAAACAACTAAAAATTGCCTTGAGTTATCACCTGAGCTACTT
ATGCCAAGGTCTTGCCTTTCTAAAGCTAATAAGGTGAGAGGTGGATATCTGTAGCTCTTCGGATGAAAAATTGCATTGTGGGAGATACCA
AAATTGAGGAAATAGCTCTTCAAAGAAAAATTACTGATATGATCATTGTACTTGTAAATGCCTTAAGTAGCAGGCAGTGACTCAATTTTC
TACTTTACCATTTTACCTTTAGCTTTTATGTATGAATTATAGGTCTGTGGAGATTCTGCCTCCCCACTAGGCCAGTGTGTGTTTACCATT
TATTCATTTTCTATCATACACAGGTGGATTAAAATTTACATTAAAATTTACATTAAAATACCATCATACTTCAGGCTTCTATAACAAAAT
ATCAGACTGGGTGGCTTCAAAAGCAGACATTTCTTACAGTTCTGGAAGCTGGGAAGTCCCACAATCCACATGCTGGTAAATTTGGTTCGT
GGTGAGGCCCCTCTTCCTCTTTTACTGACCACATCCCCAAAAGTGTCAGGTAGACATGTTACAAATAGCTCTGTAGAGAGCCATGGGAAG
AGACAGGAGGCAGATGTGGAACATAAAGGGTTTAGAAACTTCTGCAGGCAGCAGTGGCAGGGAGCAAGCCCTAGAGTGTCTCTTTTTACG
AGAGCAGGAATCCCATCATGAGAGTTCCTTCCTCATGACTTTATCTAAACCCAGTCACCCCCAACAAAGGCCCCACCCCCTAACCCCATC
ACATTGGCTGTTACGGCTTCAATGTAGGGGATGGGGCACAAACATTCAGTCCATAACGAATACTGATTCCTCAAATAGGGTTTAAACATA
GTTAACTGAGCCCCCAAAGAATGTTAAAAGAGAAAATCCATTTTATTTGAATAGATGCAGTGACCACAGCTTCTTCCCTCAAATCAACAC
ATTACAGTTAGATGTCTCCCATCTGAAATTGGATAGCCCACTGAAATTGAACATGCCTTCTCTTATAAATGTGTGGTGAGAATAAAAGCA
ACAAAGAAATGAATGTGGTGGCTCACACCTGTAATCCTAACACTTTGGAAGGTTGAGGCAGGAGGATCCTTTGTGCTCAAGAGTTTGAGA
CCAGCCTGAGCAACACAGTGAGACCCTGTCTCTACAAAAACTAAAAAAATTAGCTAGGGATGGTGGCACATGCCTGTAGTCCCAGCTACT
TGGGAGGCTGAGGTGGGAGGATTGCTTGAGCCCAAGAAGGTCAAGGCTGCCATGAGCCATAATCACGCCACTGCACTCCAGCCTGGGTGA
CAGAGACCCTGTCTTAAAATAAAATAAAAAAAAAAGGAAAAGGAAAGACATACATACCCTCAGTTCTTCGAAAAACAGTCAACGTCCAAA
AAGTTTATTTTTTGAGTCACCTTTAATAGAGAAATTTCCCACTGGAAACAGATCCACCTAAGTGATTATCTAGTATCAGCTGTATCAAGG
CAAAAGGTAAAGGTTATAAGATGTAAATATTAGACCAAAATAGCCTTTTTTAACAAACACAATAATGCTGTACGTCTGTAACAAAACAAA
ATTTGAAAAATTGAGGTAATGTACACAGCGATGCACACACCCCCACACCACACCGTGATTCCTGAGTTTTGATTTGGTTGAATTCACCTT
GTAGTTCCCTTTCCTGAGAAAATACAGGTTCAACACATCTAGTCCACGATGTACGTACAAGGGGAAGGGGTGAACAGGAAATAGACTCCC
TTATTCTGCTCACATGAGCTGGAACCTGTACTAGCTGCATATTTCATAGACCCCAGAGGCTCACCTCAATTGTACTCCTATGATAAAATG
TCTCTAGCATTTGTCATGAGAGAAACTGGCTAGAAATAGTTTGTTCATTGCGTCCAGCAAGACACGCATTGCTGTTGATATCTTTGTGGC
TAAGATGGAGAATGTGACTGGATAATAGTTATCCAGGTGGATTACTAGCTATTGAAACAGTCTGAGATAGTTGCATGATGATTAACGTTA
AACTGGGAGTAATTTCAAGTCATTTGGCTAAAAATGAAAAAAAAGTCCCATAAAAAGGTATCAAATGTACAGATAATAGGGCTGGAATTA
TTAAGTATGATGATGTTATTAACATCTAAAATTATTTTGGCCGGGCAAGGTGGGTCACGCCTGTAATCTCAGCACTTTGGGATGCCAAGA
TGGGTGGATCACCTGAGTTCAGGAGTTCAAGACCAGCTTGGCCAACATGGCGAAACCCGTCTCTACTAAAGAATACAAAAATTAGCCAGG
TGTTGTGGCACATGCCTGTACTCCCAGCTACTCAGGAGGCTGAGGCAGAAGAATCATTTGAACCCCGGAGGTGGAGGTTGCAGTGAGCCG
ACATTGTGCCGCTTCATTCCAGCCTGGGCAACAGAGTGAAACTCTTGTCTCAAAAGTAAAAAAATAATAATGTTTAAAAATATTTCAATG
TGGAGACAAGCTCAAAATGAAATTAGACACATTCCATTACCCAGGTAAAAGAAGGGGAAGCCTGACTTGATAGTAGTATTCAGGAAAAAA
GAGTTGGCAGTTTTATTTGGCCAAATTCCAATATCAGCTCATGGTACAGCACACCGGGGGAGGGGGACGGGAGGCGAGAACTAAGGCTTT
TTAAGAATGTGTTGATGGAAGTATGTGCCTAGATCAAAAGAATAATCCCCCCGGACTCCAGTGTAAGATCAATTACTGTTGGAATATTGT
GTTCCTTTCTAGATATCACATTTTAAGCAGACTTTGGCCAAGTAGTACAGTGTTTGCAGGAGCAGTAACAAGATGGTGATAACTTTGAAA
ATACTTCTCAAAAGAAAAATAAAAAAGAATTAGGGAAGTTCAGTCTGGAGATAATTCAGAAATACAGATGATAATTGTTTTCAAATTCTT
GAAGGAAATGGGAGAGAGAATAGGCTAATTCTGTATTGCTTCAGAAACCAAATGGAAACAATTAAATTCCATTAGAGAAACGGTTGGAAA
ATATGAGGAGGATTTAGTTCAGTACGAGGAAGCTGTTTCTAATACTTTTTGTTGGTTAAAAATACATTCCGCTGCTGTGGAAAGCCTGTA
GCTGCCAGGAGTGTTACAGAGGGCATTCCTCCCTTGAGTTGACATTTGTGCCAAACCGGCTTTTAGGGCTTCTCCAGCTTTTAAGATGCG
ATAATGATAAGATGATCATCGGGAAAACATCCCTCAGATGAAACGTTCACAGGCTGGCTCTGAAAACTGGCATTCAGATGATTGCGGCTC
CCCCATACTGTAGGAATATTGTTTATGGCTTAAGGTTGCCTCGCTCCTCATCTGTAATCAGTGAAAGTTTATCCAGAGGTTAATTACCGG
TTTTCTGGTGGGTATCTGGGAACTGAGGATGGGAGATTAACTGTTGTATATGACCATAGTAAAGCAAAAGACTGTTAGAGAATGAGTAAA
CGTTCGTTTTCCTCCCTACAGAATTTACAGTTACTCTCTGTCCATTCCACTCACTACTGTCTTCATCACACACACAGAGGCAAACGTCTG
ATTCAGATAGCCAGGTGTGCCATGCATGCACTCCACCATATTGTGATCTCTTCGAGGCTTGTTTCTGTCCCCTGTCCTCCACAGTCCTGG

>68346_68346_3_PPWD1-NLN_PPWD1_chr5_64875440_ENST00000535264_NLN_chr5_65076006_ENST00000380985_length(amino acids)=938AA_BP=0
MRRTKSAGLDLYLWRQHWPRRGKQPHEVGISNSYLVLEFERVYLDNLPSASMYERSYMHRDVITHVVCTKTDFIITASHDGHVKFWKKIE
EGIEFVKHFRSHLGVIESIAVSSEGALFCSVGDDKAMKVFDVVNFDMINMLKLGYFPGQCEWIYCPGDAISSVAASEKSTGKIFIYDGRG
DNQPLHIFDKLHTSPLTQIRLNPVYKAVVSSDKSGMIEYWTGPPHEYKFPKNVNWEYKTDTDLYEFAKCKAYPTSVCFSPDGKKIATIGS
DRKVRIFRFVTGKLMRVFDESLSMFTELQQMRQQLPDMEFGRRMAVERELEKVDAVRLINIVFDETGHFVLYGTMLGIKVINVETNRCVR
ILGKQENIRVMQLALFQGIAKKHRAATTIEMKASENPVLQNIQADPTIVCTSFKKNRFYMEIKSMKKRMSELCIDFNKNLNEDDTFLVFS
KAELGALPDDFIDSLEKTDDDKYKITLKYPHYFPVMKKCCIPETRRRMEMAFNTRCKEENTIILQQLLPLRTKVAKLLGYSTHADFVLEM
NTAKSTSRVTAFLDDLSQKLKPLGEAEREFILNLKKKECKDRGFEYDGKINAWDLYYYMTQTEELKYSIDQEFLKEYFPIEVVTEGLLNT
YQELLGLSFEQMTDAHVWNKSVTLYTVKDKATGEVLGQFYLDLYPREGKYNHAACFGLQPGCLLPDGSRMMAVAALVVNFSQPVAGRPSL
LRHDEVRTYFHEFGHVMHQICAQTDFARFSGTNVETDFVEVPSQMLENWVWDVDSLRRLSKHYKDGSPIADDLLEKLVASRLVNTGLLTL
RQIVLSKVDQSLHTNTSLDAASEYAKYCSEILGVAATPGTNMPATFGHLAGGYDGQYYGYLWSEVFSMDMFYSCFKKEGIMNPEVGMKYR

--------------------------------------------------------------
>68346_68346_4_PPWD1-NLN_PPWD1_chr5_64875440_ENST00000535264_NLN_chr5_65076006_ENST00000502464_length(transcript)=9327nt_BP=1402nt
GACGATGCGAACAACATGGCGGCGGAAAGTGGTAGCGATTTTCAGCAGAGACGTAGAAGGCGCCGGGACCCGGAGGAACCGGAAAAAACA
GAACTCAGCGAAAGAGAGCTGGCAGTAGCAGTGGCGGTGTCCCAGGAGAACGATGAGGAGAACGAAGAGCGCTGGGTTGGACCTTTACCT
GTGGAGGCAACACTGGCCAAGAAGAGGAAAGCAGCCACATGAAGTTGGAATTTCGAACTCTTATTTAGTCTTAGAGTTTGAAAGAGTCTA
TCTTGATAATCTCCCCAGTGCATCCATGTATGAGCGCAGTTACATGCATAGAGATGTTATCACCCATGTGGTATGCACCAAAACAGATTT
TATTATTACTGCCAGTCATGATGGACATGTCAAGTTCTGGAAAAAAATAGAAGAGGGAATTGAATTTGTTAAACATTTTCGTAGTCACCT
GGGAGTTATTGAGAGTATTGCAGTTAGCTCTGAGGGAGCATTGTTCTGTTCTGTGGGTGATGATAAAGCAATGAAGGTGTTTGATGTAGT
GAACTTTGACATGATCAACATGCTGAAACTTGGCTATTTTCCTGGACAGTGTGAGTGGATCTATTGCCCAGGGGATGCAATTTCTTCAGT
TGCTGCTTCCGAAAAGAGTACAGGAAAAATTTTCATTTATGATGGCCGAGGAGATAACCAGCCACTTCATATTTTTGACAAACTCCATAC
ATCACCTCTTACTCAGATACGGCTAAACCCAGTTTACAAAGCAGTAGTGTCTTCTGACAAATCTGGGATGATTGAATACTGGACTGGGCC
TCCTCATGAATATAAATTCCCCAAAAATGTGAACTGGGAATATAAAACTGACACTGATTTATATGAATTTGCCAAGTGTAAGGCTTATCC
AACCAGCGTATGTTTTTCACCAGATGGGAAGAAAATAGCTACTATTGGTTCTGATAGAAAAGTTAGAATTTTCAGATTTGTAACTGGAAA
ACTCATGAGAGTCTTTGATGAATCACTAAGCATGTTTACTGAACTGCAACAGATGAGGCAACAGTTACCAGACATGGAATTTGGCCGACG
AATGGCTGTAGAACGTGAGTTGGAGAAGGTTGATGCTGTAAGATTAATTAATATAGTTTTTGATGAAACTGGACACTTCGTGCTGTATGG
AACAATGCTGGGCATTAAAGTTATAAATGTAGAGACAAACCGGTGTGTGCGGATTTTAGGCAAACAAGAAAATATTAGAGTGATGCAATT
GGCTTTGTTCCAGGGGATAGCCAAAAAGCATCGTGCTGCAACTACTATAGAAATGAAAGCTTCTGAAAATCCTGTTCTTCAGAATATTCA
AGCTGACCCAACAATAGTCTGTACATCATTCAAAAAGAATAGATTTTATATGGAAATCAAATCAATGAAGAAAAGAATGAGTGAGCTATG
TATTGATTTTAACAAAAACCTCAATGAGGATGATACCTTCCTTGTATTTTCCAAGGCTGAACTTGGTGCTCTTCCTGATGATTTCATTGA
CAGTTTAGAAAAGACAGATGATGACAAGTATAAAATTACCTTAAAATATCCACACTATTTCCCTGTCATGAAGAAATGTTGTATCCCTGA
AACCAGAAGAAGGATGGAAATGGCTTTTAATACAAGGTGCAAAGAGGAAAACACCATAATTTTGCAGCAGCTACTCCCACTGCGAACCAA
GGTGGCCAAACTACTCGGTTATAGCACACATGCTGACTTCGTCCTTGAAATGAACACTGCAAAGAGCACAAGCCGCGTAACAGCCTTTCT
AGATGATTTAAGCCAGAAGTTAAAACCCTTGGGTGAAGCAGAACGAGAGTTTATTTTGAATTTGAAGAAAAAGGAATGCAAAGACAGGGG
TTTTGAATATGATGGGAAAATCAATGCCTGGGATCTATATTACTACATGACTCAGACAGAGGAACTCAAGTATTCCATAGACCAAGAGTT
CCTCAAGGAATACTTCCCAATTGAGGTGGTCACTGAAGGCTTGCTGAACACCTACCAGGAGTTGTTGGGACTTTCATTTGAACAAATGAC
AGATGCTCATGTTTGGAACAAGAGTGTTACACTTTATACTGTGAAGGATAAAGCTACAGGAGAAGTATTGGGACAGTTCTATTTGGACCT
CTATCCAAGGGAAGGAAAATACAATCATGCGGCCTGCTTCGGTCTCCAGCCTGGCTGCCTTCTGCCTGATGGAAGCCGGATGATGGCAGT
GGCTGCCCTCGTGGTGAACTTCTCACAGCCAGTGGCAGGTCGTCCCTCTCTCCTGAGACACGACGAGGTGAGGACTTACTTTCATGAGTT
TGGTCACGTGATGCATCAGATTTGTGCACAGACTGATTTTGCACGATTTAGCGGAACAAATGTGGAAACTGACTTTGTAGAGGTGCCATC
GCAAATGCTTGAAAATTGGGTGTGGGACGTCGATTCCCTCCGAAGATTGTCAAAACATTATAAAGATGGAAGCCCTATTGCAGACGATCT
GCTTGAAAAACTTGTTGCTTCTAGGCTGGTCAACACAGGTCTTCTGACCCTGCGCCAGATTGTTTTGAGCAAAGTTGATCAGTCTCTTCA
TACCAACACATCGCTGGATGCTGCAAGTGAATATGCCAAATACTGCTCAGAAATATTAGGAGTTGCAGCTACTCCAGGCACAAATATGCC
AGCTACCTTTGGACATTTGGCAGGGGGATACGATGGCCAATATTATGGATATCTTTGGAGTGAAGTATTTTCCATGGATATGTTTTACAG
CTGTTTTAAAAAAGAAGGGATAATGAATCCAGAGGTTGGAATGAAATACAGAAACCTAATCCTGAAACCTGGGGGATCTCTGGACGGCAT
GGACATGCTCCACAATTTCTTGAAACGTGAGCCAAACCAAAAAGCGTTCCTAATGAGTAGAGGCCTGCATGCTCCGTGAACTGGGGATCT
TTGGTAGCCGTCCATGTCTGGAGGACAAGTCGACATCACCATGTGTTACTGGCCTGGAAACTGAAGGGAGTTTTGCAAGTGAAAATTTAG
ATTTCTATTGACATCCTTTTGTTTTCTAATTTTAAAAATTATAAAGATGTAAATGGAATTATAAATACTGTGACCTAAGAAAAGACCCAC
TAGAAAGTAATTGTACTATAAAATTTCATAAAACTGGATTTGATTTCTTTTTATGAAAGTTTCATATGAATGTAACTTGATTTTTTACTA
TTATAATCTAGATAATATGATATAAGAGGGCTAAGAATTTTTAAATTGAATCATATATATGATATAATTTGATCCTTCTTGTATCTTGAA
GTTTTGTACTTGGGATTTCTGGACTGATAAATGAATCATCACATTCTTCTGGTAAATATTTTCTTGGAGCTCTGTGTCAACTTTGATCCT
TTGTCTCCCAGGAAGGTGTGACCTCTCCTTTGCCTGCATACCTCAAGGCCAGGGGAATATGCCTCAGTGATGCATTTATCTTTGTATATC
AGGCCGCATGATTCCCAACTTTCTGCCACACTTAAATTACGTTCCTCCATTTCAGTTTTGTCTTTTCTGTCTAAAGTTCAGTCAAAGAGT
ATCAAAAAATTATGTTTCAGCTAGACTGGTGTAATGTATAAGTTTTTGTATCTTGTATTAGAGGATTTCGTAGCTTTTATTAGAGGCTCA
TTTCCACCTCAGCATACAAGATCGTTAGTCTTTTGGCATGTGTGCCAATTAGAATACTAAAGCAAGTCCAAGCACATTTTTCTCTTCTCA
CGTTTCTAATAAGTGTTAGGGACTTTGCCTCTTTTACTTACCACGTCCCCAAAAGTGTCAGGTAGACATGTCACAAATGGCTCTGTAGAG
AGCCATGGGAAGAGAGAGGAGGTGGATGTGGAACATAAAGGGTTCAGAAACTCCAGAAGAGGAGTGGGTTTTGGATAGAAGCATTTGAGG
ACAGCTGCTCCAAAGCCTTATGTGTATGATGAAACTTAACCACGGGGAAGAGACTCTTCAGTAGCCTGTTCTGTCTGGTGATTTTTATTT
TAAGTGAACCTTTGGATCTATCTTTAACTCTCTTTATTGTGAGTCTAAATTCCAATTCTGCAGCAGATCAGTAAACTCACAGTATTTTTC
CTGTGGAAATCTATTCAATAAGGAAACCAAGACAGGATAATAAAATTTAAAAAAAAAACAACTTTGAATTCCCCTGCCTAGGTCTTCCAG
TTGTTTTCCAGCGCATACCTCAGGTATGACTTTGCTAGCCGGGGACAAAATTAGCACCTTCCGATTCTCTAGTCCAAATGAACTTTGTGC
TAAATAAAAAATTATTATACTACATAATAAAGTTACAGATAGCAGGAAATGCAAGAGCTAGGAGATTCCTAGATTATATCTGCCAAGCAA
ATACCTTAAACATCCACCTGAAATCCTACTACCCCCTCTTCTGAGATAATTTGCCCAGCCCTTCTCTTCCCACACACTCACTCAATGTCA
CCCCCTTCTAATCCCCAAAACTGTTTTTGTGGTCTTTGTAGCCTATAGTAGTTTTCTCACATCTTTCCCCCTAGACTTTTCTGTTTTTCA
GTTTCAGACAAAAAAACTCTTCAGCTTTTTCCAGTGTGTCTCCTTAACAGTAACTTTACCACTTGAAATCTTATTTCATAGAAAAACTAA
ATTGGTGTGGAAAGGCTGCACACAATAAAGTTATATTATTATCCATGAAAATGAACTCATATTTCTTTCATACTTTAACGTTAAAACCGA
AATGCATGAGAGCAAAAGCACCATGGTGTTCTTTCTATTTAGGGCCTACCTCTAATATTTAAAATCTACCAAAGAGCAGTCACAAAATTA
AAACTCAGCCCGGGCGCAGTGGCTCATGCCTGTAATCCCAGCACTTTGGGAGGCCAAGGCAGGAGGATCACCTGAGGTCAGAGTTCAAGA
CCAGCATGGTCAACATGGTGAAACCCTGTCTCTACAAAAATACAAAAAGCTGGGCATGATGTTGGGTTCCTGTAGTCCCAGCTACTTAGG
AGGCTGAGGCAGGAGAATAGCTTGAACCCGGGAGGTGGAGGTTGCAGTGAGCTGAGATCATGCCATTGCACTCCAGCCTGGACGACAGAG
TGAGATTCAGTCTCAAAAAAAATTAATACTCAAAGAATTATCTAGCATAATTTAAAAGAAAGGACTTTTTAAAAATTCTCTAGCATAATT
CAAAAGAAAGGACTTAACTTTTTTTTTTTTAGTGTGGTCATCCGTCTAGTTGTTCTTTTTTTCCAGATCAGAGCAGAGAATATCACTGAC
ATGCTTGAAATGGTGGATAACTATGTAAATTGTAATTGGACAAATGTACACTTTAGATTTATGGACTGAGCCACATATAATAAGGTCTCT
CCTGGTAATTGATCCAGGGGATTTAGGCCTCTTTCGGGTTTTTTGTTTTTTTTTTAGGCATTGTTATGTTGTGAAGGATAAAATCTTCAA
CATCTTATGCAAATGGATAGTAGGCATGATCCTAAAGGTTTAGTTTTACGATGCTGCAGAGAAGAGAAATGTCTTGACGTTTTGCCACCT
GATGTAGACTTTGTCCCCCTCTAGTATAAATGTTGCATGTTACCTAGATAAACAACTAAAAATTGCCTTGAGTTATCACCTGAGCTACTT
ATGCCAAGGTCTTGCCTTTCTAAAGCTAATAAGGTGAGAGGTGGATATCTGTAGCTCTTCGGATGAAAAATTGCATTGTGGGAGATACCA
AAATTGAGGAAATAGCTCTTCAAAGAAAAATTACTGATATGATCATTGTACTTGTAAATGCCTTAAGTAGCAGGCAGTGACTCAATTTTC
TACTTTACCATTTTACCTTTAGCTTTTATGTATGAATTATAGGTCTGTGGAGATTCTGCCTCCCCACTAGGCCAGTGTGTGTTTACCATT
TATTCATTTTCTATCATACACAGGTGGATTAAAATTTACATTAAAATTTACATTAAAATACCATCATACTTCAGGCTTCTATAACAAAAT
ATCAGACTGGGTGGCTTCAAAAGCAGACATTTCTTACAGTTCTGGAAGCTGGGAAGTCCCACAATCCACATGCTGGTAAATTTGGTTCGT
GGTGAGGCCCCTCTTCCTCTTTTACTGACCACATCCCCAAAAGTGTCAGGTAGACATGTTACAAATAGCTCTGTAGAGAGCCATGGGAAG
AGACAGGAGGCAGATGTGGAACATAAAGGGTTTAGAAACTTCTGCAGGCAGCAGTGGCAGGGAGCAAGCCCTAGAGTGTCTCTTTTTACG
AGAGCAGGAATCCCATCATGAGAGTTCCTTCCTCATGACTTTATCTAAACCCAGTCACCCCCAACAAAGGCCCCACCCCCTAACCCCATC
ACATTGGCTGTTACGGCTTCAATGTAGGGGATGGGGCACAAACATTCAGTCCATAACGAATACTGATTCCTCAAATAGGGTTTAAACATA
GTTAACTGAGCCCCCAAAGAATGTTAAAAGAGAAAATCCATTTTATTTGAATAGATGCAGTGACCACAGCTTCTTCCCTCAAATCAACAC
ATTACAGTTAGATGTCTCCCATCTGAAATTGGATAGCCCACTGAAATTGAACATGCCTTCTCTTATAAATGTGTGGTGAGAATAAAAGCA
ACAAAGAAATGAATGTGGTGGCTCACACCTGTAATCCTAACACTTTGGAAGGTTGAGGCAGGAGGATCCTTTGTGCTCAAGAGTTTGAGA
CCAGCCTGAGCAACACAGTGAGACCCTGTCTCTACAAAAACTAAAAAAATTAGCTAGGGATGGTGGCACATGCCTGTAGTCCCAGCTACT
TGGGAGGCTGAGGTGGGAGGATTGCTTGAGCCCAAGAAGGTCAAGGCTGCCATGAGCCATAATCACGCCACTGCACTCCAGCCTGGGTGA
CAGAGACCCTGTCTTAAAATAAAATAAAAAAAAAAGGAAAAGGAAAGACATACATACCCTCAGTTCTTCGAAAAACAGTCAACGTCCAAA
AAGTTTATTTTTTGAGTCACCTTTAATAGAGAAATTTCCCACTGGAAACAGATCCACCTAAGTGATTATCTAGTATCAGCTGTATCAAGG
CAAAAGGTAAAGGTTATAAGATGTAAATATTAGACCAAAATAGCCTTTTTTAACAAACACAATAATGCTGTACGTCTGTAACAAAACAAA
ATTTGAAAAATTGAGGTAATGTACACAGCGATGCACACACCCCCACACCACACCGTGATTCCTGAGTTTTGATTTGGTTGAATTCACCTT
GTAGTTCCCTTTCCTGAGAAAATACAGGTTCAACACATCTAGTCCACGATGTACGTACAAGGGGAAGGGGTGAACAGGAAATAGACTCCC
TTATTCTGCTCACATGAGCTGGAACCTGTACTAGCTGCATATTTCATAGACCCCAGAGGCTCACCTCAATTGTACTCCTATGATAAAATG
TCTCTAGCATTTGTCATGAGAGAAACTGGCTAGAAATAGTTTGTTCATTGCGTCCAGCAAGACACGCATTGCTGTTGATATCTTTGTGGC
TAAGATGGAGAATGTGACTGGATAATAGTTATCCAGGTGGATTACTAGCTATTGAAACAGTCTGAGATAGTTGCATGATGATTAACGTTA
AACTGGGAGTAATTTCAAGTCATTTGGCTAAAAATGAAAAAAAAGTCCCATAAAAAGGTATCAAATGTACAGATAATAGGGCTGGAATTA
TTAAGTATGATGATGTTATTAACATCTAAAATTATTTTGGCCGGGCAAGGTGGGTCACGCCTGTAATCTCAGCACTTTGGGATGCCAAGA
TGGGTGGATCACCTGAGTTCAGGAGTTCAAGACCAGCTTGGCCAACATGGCGAAACCCGTCTCTACTAAAGAATACAAAAATTAGCCAGG
TGTTGTGGCACATGCCTGTACTCCCAGCTACTCAGGAGGCTGAGGCAGAAGAATCATTTGAACCCCGGAGGTGGAGGTTGCAGTGAGCCG
ACATTGTGCCGCTTCATTCCAGCCTGGGCAACAGAGTGAAACTCTTGTCTCAAAAGTAAAAAAATAATAATGTTTAAAAATATTTCAATG
TGGAGACAAGCTCAAAATGAAATTAGACACATTCCATTACCCAGGTAAAAGAAGGGGAAGCCTGACTTGATAGTAGTATTCAGGAAAAAA
GAGTTGGCAGTTTTATTTGGCCAAATTCCAATATCAGCTCATGGTACAGCACACCGGGGGAGGGGGACGGGAGGCGAGAACTAAGGCTTT
TTAAGAATGTGTTGATGGAAGTATGTGCCTAGATCAAAAGAATAATCCCCCCGGACTCCAGTGTAAGATCAATTACTGTTGGAATATTGT
GTTCCTTTCTAGATATCACATTTTAAGCAGACTTTGGCCAAGTAGTACAGTGTTTGCAGGAGCAGTAACAAGATGGTGATAACTTTGAAA
ATACTTCTCAAAAGAAAAATAAAAAAGAATTAGGGAAGTTCAGTCTGGAGATAATTCAGAAATACAGATGATAATTGTTTTCAAATTCTT
GAAGGAAATGGGAGAGAGAATAGGCTAATTCTGTATTGCTTCAGAAACCAAATGGAAACAATTAAATTCCATTAGAGAAACGGTTGGAAA
ATATGAGGAGGATTTAGTTCAGTACGAGGAAGCTGTTTCTAATACTTTTTGTTGGTTAAAAATACATTCCGCTGCTGTGGAAAGCCTGTA
GCTGCCAGGAGTGTTACAGAGGGCATTCCTCCCTTGAGTTGACATTTGTGCCAAACCGGCTTTTAGGGCTTCTCCAGCTTTTAAGATGCG
ATAATGATAAGATGATCATCGGGAAAACATCCCTCAGATGAAACGTTCACAGGCTGGCTCTGAAAACTGGCATTCAGATGATTGCGGCTC
CCCCATACTGTAGGAATATTGTTTATGGCTTAAGGTTGCCTCGCTCCTCATCTGTAATCAGTGAAAGTTTATCCAGAGGTTAATTACCGG
TTTTCTGGTGGGTATCTGGGAACTGAGGATGGGAGATTAACTGTTGTATATGACCATAGTAAAGCAAAAGACTGTTAGAGAATGAGTAAA
CGTTCGTTTTCCTCCCTACAGAATTTACAGTTACTCTCTGTCCATTCCACTCACTACTGTCTTCATCACACACACAGAGGCAAACGTCTG
ATTCAGATAGCCAGGTGTGCCATGCATGCACTCCACCATATTGTGATCTCTTCGAGGCTTGTTTCTGTCCCCTGTCCTCCACAGTCCTGG

>68346_68346_4_PPWD1-NLN_PPWD1_chr5_64875440_ENST00000535264_NLN_chr5_65076006_ENST00000502464_length(amino acids)=938AA_BP=0
MRRTKSAGLDLYLWRQHWPRRGKQPHEVGISNSYLVLEFERVYLDNLPSASMYERSYMHRDVITHVVCTKTDFIITASHDGHVKFWKKIE
EGIEFVKHFRSHLGVIESIAVSSEGALFCSVGDDKAMKVFDVVNFDMINMLKLGYFPGQCEWIYCPGDAISSVAASEKSTGKIFIYDGRG
DNQPLHIFDKLHTSPLTQIRLNPVYKAVVSSDKSGMIEYWTGPPHEYKFPKNVNWEYKTDTDLYEFAKCKAYPTSVCFSPDGKKIATIGS
DRKVRIFRFVTGKLMRVFDESLSMFTELQQMRQQLPDMEFGRRMAVERELEKVDAVRLINIVFDETGHFVLYGTMLGIKVINVETNRCVR
ILGKQENIRVMQLALFQGIAKKHRAATTIEMKASENPVLQNIQADPTIVCTSFKKNRFYMEIKSMKKRMSELCIDFNKNLNEDDTFLVFS
KAELGALPDDFIDSLEKTDDDKYKITLKYPHYFPVMKKCCIPETRRRMEMAFNTRCKEENTIILQQLLPLRTKVAKLLGYSTHADFVLEM
NTAKSTSRVTAFLDDLSQKLKPLGEAEREFILNLKKKECKDRGFEYDGKINAWDLYYYMTQTEELKYSIDQEFLKEYFPIEVVTEGLLNT
YQELLGLSFEQMTDAHVWNKSVTLYTVKDKATGEVLGQFYLDLYPREGKYNHAACFGLQPGCLLPDGSRMMAVAALVVNFSQPVAGRPSL
LRHDEVRTYFHEFGHVMHQICAQTDFARFSGTNVETDFVEVPSQMLENWVWDVDSLRRLSKHYKDGSPIADDLLEKLVASRLVNTGLLTL
RQIVLSKVDQSLHTNTSLDAASEYAKYCSEILGVAATPGTNMPATFGHLAGGYDGQYYGYLWSEVFSMDMFYSCFKKEGIMNPEVGMKYR

--------------------------------------------------------------
>68346_68346_5_PPWD1-NLN_PPWD1_chr5_64875440_ENST00000538977_NLN_chr5_65076006_ENST00000380985_length(transcript)=9184nt_BP=1259nt
GATGCGAACAACATGGCGGCGGAAAGTGGTAGCGATTTTCAGCAGAGACGTAGAAGGCGCCGGGACCCGGAGGAACCGGAAAAAACAGAA
CTCAGCGAAAGAGAGCTGGCAGTAGCAGTGGCGGTGTCCCAGGAGAACGATGAGGAGAACGAAGAGCGCTGGGTTGGACCTTTACCTGTG
GAGGCAACACTGGCCAAGAAGAGGAAAGAACAGATTTTATTATTACTGCCAGTCATGATGGACATGTCAAGTTCTGGAAAAAAATAGAAG
AGGGAATTGAATTTGTTAAACATTTTCGTAGTCACCTGGGAGTTATTGAGAGTATTGCAGTTAGCTCTGAGGGAGCATTGTTCTGTTCTG
TGGGTGATGATAAAGCAATGAAGGTGTTTGATGTAGTGAACTTTGACATGATCAACATGCTGAAACTTGGCTATTTTCCTGGACAGTGTG
AGTGGATCTATTGCCCAGGGGATGCAATTTCTTCAGTTGCTGCTTCCGAAAAGAGTACAGGAAAAATTTTCATTTATGATGGCCGAGGAG
ATAACCAGCCACTTCATATTTTTGACAAACTCCATACATCACCTCTTACTCAGATACGGCTAAACCCAGTTTACAAAGCAGTAGTGTCTT
CTGACAAATCTGGGATGATTGAATACTGGACTGGGCCTCCTCATGAATATAAATTCCCCAAAAATGTGAACTGGGAATATAAAACTGACA
CTGATTTATATGAATTTGCCAAGTGTAAGGCTTATCCAACCAGCGTATGTTTTTCACCAGATGGGAAGAAAATAGCTACTATTGGTTCTG
ATAGAAAAGTTAGAATTTTCAGATTTGTAACTGGAAAACTCATGAGAGTCTTTGATGAATCACTAAGCATGTTTACTGAACTGCAACAGA
TGAGGCAACAGTTACCAGACATGGAATTTGGCCGACGAATGGCTGTAGAACGTGAGTTGGAGAAGGTTGATGCTGTAAGATTAATTAATA
TAGTTTTTGATGAAACTGGACACTTCGTGCTGTATGGAACAATGCTGGGCATTAAAGTTATAAATGTAGAGACAAACCGGTGTGTGCGGA
TTTTAGGCAAACAAGAAAATATTAGAGTGATGCAATTGGCTTTGTTCCAGGGGATAGCCAAAAAGCATCGTGCTGCAACTACTATAGAAA
TGAAAGCTTCTGAAAATCCTGTTCTTCAGAATATTCAAGCTGACCCAACAATAGTCTGTACATCATTCAAAAAGAATAGATTTTATATGG
AAATCAAATCAATGAAGAAAAGAATGAGTGAGCTATGTATTGATTTTAACAAAAACCTCAATGAGGATGATACCTTCCTTGTATTTTCCA
AGGCTGAACTTGGTGCTCTTCCTGATGATTTCATTGACAGTTTAGAAAAGACAGATGATGACAAGTATAAAATTACCTTAAAATATCCAC
ACTATTTCCCTGTCATGAAGAAATGTTGTATCCCTGAAACCAGAAGAAGGATGGAAATGGCTTTTAATACAAGGTGCAAAGAGGAAAACA
CCATAATTTTGCAGCAGCTACTCCCACTGCGAACCAAGGTGGCCAAACTACTCGGTTATAGCACACATGCTGACTTCGTCCTTGAAATGA
ACACTGCAAAGAGCACAAGCCGCGTAACAGCCTTTCTAGATGATTTAAGCCAGAAGTTAAAACCCTTGGGTGAAGCAGAACGAGAGTTTA
TTTTGAATTTGAAGAAAAAGGAATGCAAAGACAGGGGTTTTGAATATGATGGGAAAATCAATGCCTGGGATCTATATTACTACATGACTC
AGACAGAGGAACTCAAGTATTCCATAGACCAAGAGTTCCTCAAGGAATACTTCCCAATTGAGGTGGTCACTGAAGGCTTGCTGAACACCT
ACCAGGAGTTGTTGGGACTTTCATTTGAACAAATGACAGATGCTCATGTTTGGAACAAGAGTGTTACACTTTATACTGTGAAGGATAAAG
CTACAGGAGAAGTATTGGGACAGTTCTATTTGGACCTCTATCCAAGGGAAGGAAAATACAATCATGCGGCCTGCTTCGGTCTCCAGCCTG
GCTGCCTTCTGCCTGATGGAAGCCGGATGATGGCAGTGGCTGCCCTCGTGGTGAACTTCTCACAGCCAGTGGCAGGTCGTCCCTCTCTCC
TGAGACACGACGAGGTGAGGACTTACTTTCATGAGTTTGGTCACGTGATGCATCAGATTTGTGCACAGACTGATTTTGCACGATTTAGCG
GAACAAATGTGGAAACTGACTTTGTAGAGGTGCCATCGCAAATGCTTGAAAATTGGGTGTGGGACGTCGATTCCCTCCGAAGATTGTCAA
AACATTATAAAGATGGAAGCCCTATTGCAGACGATCTGCTTGAAAAACTTGTTGCTTCTAGGCTGGTCAACACAGGTCTTCTGACCCTGC
GCCAGATTGTTTTGAGCAAAGTTGATCAGTCTCTTCATACCAACACATCGCTGGATGCTGCAAGTGAATATGCCAAATACTGCTCAGAAA
TATTAGGAGTTGCAGCTACTCCAGGCACAAATATGCCAGCTACCTTTGGACATTTGGCAGGGGGATACGATGGCCAATATTATGGATATC
TTTGGAGTGAAGTATTTTCCATGGATATGTTTTACAGCTGTTTTAAAAAAGAAGGGATAATGAATCCAGAGGTTGGAATGAAATACAGAA
ACCTAATCCTGAAACCTGGGGGATCTCTGGACGGCATGGACATGCTCCACAATTTCTTGAAACGTGAGCCAAACCAAAAAGCGTTCCTAA
TGAGTAGAGGCCTGCATGCTCCGTGAACTGGGGATCTTTGGTAGCCGTCCATGTCTGGAGGACAAGTCGACATCACCATGTGTTACTGGC
CTGGAAACTGAAGGGAGTTTTGCAAGTGAAAATTTAGATTTCTATTGACATCCTTTTGTTTTCTAATTTTAAAAATTATAAAGATGTAAA
TGGAATTATAAATACTGTGACCTAAGAAAAGACCCACTAGAAAGTAATTGTACTATAAAATTTCATAAAACTGGATTTGATTTCTTTTTA
TGAAAGTTTCATATGAATGTAACTTGATTTTTTACTATTATAATCTAGATAATATGATATAAGAGGGCTAAGAATTTTTAAATTGAATCA
TATATATGATATAATTTGATCCTTCTTGTATCTTGAAGTTTTGTACTTGGGATTTCTGGACTGATAAATGAATCATCACATTCTTCTGGT
AAATATTTTCTTGGAGCTCTGTGTCAACTTTGATCCTTTGTCTCCCAGGAAGGTGTGACCTCTCCTTTGCCTGCATACCTCAAGGCCAGG
GGAATATGCCTCAGTGATGCATTTATCTTTGTATATCAGGCCGCATGATTCCCAACTTTCTGCCACACTTAAATTACGTTCCTCCATTTC
AGTTTTGTCTTTTCTGTCTAAAGTTCAGTCAAAGAGTATCAAAAAATTATGTTTCAGCTAGACTGGTGTAATGTATAAGTTTTTGTATCT
TGTATTAGAGGATTTCGTAGCTTTTATTAGAGGCTCATTTCCACCTCAGCATACAAGATCGTTAGTCTTTTGGCATGTGTGCCAATTAGA
ATACTAAAGCAAGTCCAAGCACATTTTTCTCTTCTCACGTTTCTAATAAGTGTTAGGGACTTTGCCTCTTTTACTTACCACGTCCCCAAA
AGTGTCAGGTAGACATGTCACAAATGGCTCTGTAGAGAGCCATGGGAAGAGAGAGGAGGTGGATGTGGAACATAAAGGGTTCAGAAACTC
CAGAAGAGGAGTGGGTTTTGGATAGAAGCATTTGAGGACAGCTGCTCCAAAGCCTTATGTGTATGATGAAACTTAACCACGGGGAAGAGA
CTCTTCAGTAGCCTGTTCTGTCTGGTGATTTTTATTTTAAGTGAACCTTTGGATCTATCTTTAACTCTCTTTATTGTGAGTCTAAATTCC
AATTCTGCAGCAGATCAGTAAACTCACAGTATTTTTCCTGTGGAAATCTATTCAATAAGGAAACCAAGACAGGATAATAAAATTTAAAAA
AAAAACAACTTTGAATTCCCCTGCCTAGGTCTTCCAGTTGTTTTCCAGCGCATACCTCAGGTATGACTTTGCTAGCCGGGGACAAAATTA
GCACCTTCCGATTCTCTAGTCCAAATGAACTTTGTGCTAAATAAAAAATTATTATACTACATAATAAAGTTACAGATAGCAGGAAATGCA
AGAGCTAGGAGATTCCTAGATTATATCTGCCAAGCAAATACCTTAAACATCCACCTGAAATCCTACTACCCCCTCTTCTGAGATAATTTG
CCCAGCCCTTCTCTTCCCACACACTCACTCAATGTCACCCCCTTCTAATCCCCAAAACTGTTTTTGTGGTCTTTGTAGCCTATAGTAGTT
TTCTCACATCTTTCCCCCTAGACTTTTCTGTTTTTCAGTTTCAGACAAAAAAACTCTTCAGCTTTTTCCAGTGTGTCTCCTTAACAGTAA
CTTTACCACTTGAAATCTTATTTCATAGAAAAACTAAATTGGTGTGGAAAGGCTGCACACAATAAAGTTATATTATTATCCATGAAAATG
AACTCATATTTCTTTCATACTTTAACGTTAAAACCGAAATGCATGAGAGCAAAAGCACCATGGTGTTCTTTCTATTTAGGGCCTACCTCT
AATATTTAAAATCTACCAAAGAGCAGTCACAAAATTAAAACTCAGCCCGGGCGCAGTGGCTCATGCCTGTAATCCCAGCACTTTGGGAGG
CCAAGGCAGGAGGATCACCTGAGGTCAGAGTTCAAGACCAGCATGGTCAACATGGTGAAACCCTGTCTCTACAAAAATACAAAAAGCTGG
GCATGATGTTGGGTTCCTGTAGTCCCAGCTACTTAGGAGGCTGAGGCAGGAGAATAGCTTGAACCCGGGAGGTGGAGGTTGCAGTGAGCT
GAGATCATGCCATTGCACTCCAGCCTGGACGACAGAGTGAGATTCAGTCTCAAAAAAAATTAATACTCAAAGAATTATCTAGCATAATTT
AAAAGAAAGGACTTTTTAAAAATTCTCTAGCATAATTCAAAAGAAAGGACTTAACTTTTTTTTTTTTAGTGTGGTCATCCGTCTAGTTGT
TCTTTTTTTCCAGATCAGAGCAGAGAATATCACTGACATGCTTGAAATGGTGGATAACTATGTAAATTGTAATTGGACAAATGTACACTT
TAGATTTATGGACTGAGCCACATATAATAAGGTCTCTCCTGGTAATTGATCCAGGGGATTTAGGCCTCTTTCGGGTTTTTTGTTTTTTTT
TTAGGCATTGTTATGTTGTGAAGGATAAAATCTTCAACATCTTATGCAAATGGATAGTAGGCATGATCCTAAAGGTTTAGTTTTACGATG
CTGCAGAGAAGAGAAATGTCTTGACGTTTTGCCACCTGATGTAGACTTTGTCCCCCTCTAGTATAAATGTTGCATGTTACCTAGATAAAC
AACTAAAAATTGCCTTGAGTTATCACCTGAGCTACTTATGCCAAGGTCTTGCCTTTCTAAAGCTAATAAGGTGAGAGGTGGATATCTGTA
GCTCTTCGGATGAAAAATTGCATTGTGGGAGATACCAAAATTGAGGAAATAGCTCTTCAAAGAAAAATTACTGATATGATCATTGTACTT
GTAAATGCCTTAAGTAGCAGGCAGTGACTCAATTTTCTACTTTACCATTTTACCTTTAGCTTTTATGTATGAATTATAGGTCTGTGGAGA
TTCTGCCTCCCCACTAGGCCAGTGTGTGTTTACCATTTATTCATTTTCTATCATACACAGGTGGATTAAAATTTACATTAAAATTTACAT
TAAAATACCATCATACTTCAGGCTTCTATAACAAAATATCAGACTGGGTGGCTTCAAAAGCAGACATTTCTTACAGTTCTGGAAGCTGGG
AAGTCCCACAATCCACATGCTGGTAAATTTGGTTCGTGGTGAGGCCCCTCTTCCTCTTTTACTGACCACATCCCCAAAAGTGTCAGGTAG
ACATGTTACAAATAGCTCTGTAGAGAGCCATGGGAAGAGACAGGAGGCAGATGTGGAACATAAAGGGTTTAGAAACTTCTGCAGGCAGCA
GTGGCAGGGAGCAAGCCCTAGAGTGTCTCTTTTTACGAGAGCAGGAATCCCATCATGAGAGTTCCTTCCTCATGACTTTATCTAAACCCA
GTCACCCCCAACAAAGGCCCCACCCCCTAACCCCATCACATTGGCTGTTACGGCTTCAATGTAGGGGATGGGGCACAAACATTCAGTCCA
TAACGAATACTGATTCCTCAAATAGGGTTTAAACATAGTTAACTGAGCCCCCAAAGAATGTTAAAAGAGAAAATCCATTTTATTTGAATA
GATGCAGTGACCACAGCTTCTTCCCTCAAATCAACACATTACAGTTAGATGTCTCCCATCTGAAATTGGATAGCCCACTGAAATTGAACA
TGCCTTCTCTTATAAATGTGTGGTGAGAATAAAAGCAACAAAGAAATGAATGTGGTGGCTCACACCTGTAATCCTAACACTTTGGAAGGT
TGAGGCAGGAGGATCCTTTGTGCTCAAGAGTTTGAGACCAGCCTGAGCAACACAGTGAGACCCTGTCTCTACAAAAACTAAAAAAATTAG
CTAGGGATGGTGGCACATGCCTGTAGTCCCAGCTACTTGGGAGGCTGAGGTGGGAGGATTGCTTGAGCCCAAGAAGGTCAAGGCTGCCAT
GAGCCATAATCACGCCACTGCACTCCAGCCTGGGTGACAGAGACCCTGTCTTAAAATAAAATAAAAAAAAAAGGAAAAGGAAAGACATAC
ATACCCTCAGTTCTTCGAAAAACAGTCAACGTCCAAAAAGTTTATTTTTTGAGTCACCTTTAATAGAGAAATTTCCCACTGGAAACAGAT
CCACCTAAGTGATTATCTAGTATCAGCTGTATCAAGGCAAAAGGTAAAGGTTATAAGATGTAAATATTAGACCAAAATAGCCTTTTTTAA
CAAACACAATAATGCTGTACGTCTGTAACAAAACAAAATTTGAAAAATTGAGGTAATGTACACAGCGATGCACACACCCCCACACCACAC
CGTGATTCCTGAGTTTTGATTTGGTTGAATTCACCTTGTAGTTCCCTTTCCTGAGAAAATACAGGTTCAACACATCTAGTCCACGATGTA
CGTACAAGGGGAAGGGGTGAACAGGAAATAGACTCCCTTATTCTGCTCACATGAGCTGGAACCTGTACTAGCTGCATATTTCATAGACCC
CAGAGGCTCACCTCAATTGTACTCCTATGATAAAATGTCTCTAGCATTTGTCATGAGAGAAACTGGCTAGAAATAGTTTGTTCATTGCGT
CCAGCAAGACACGCATTGCTGTTGATATCTTTGTGGCTAAGATGGAGAATGTGACTGGATAATAGTTATCCAGGTGGATTACTAGCTATT
GAAACAGTCTGAGATAGTTGCATGATGATTAACGTTAAACTGGGAGTAATTTCAAGTCATTTGGCTAAAAATGAAAAAAAAGTCCCATAA
AAAGGTATCAAATGTACAGATAATAGGGCTGGAATTATTAAGTATGATGATGTTATTAACATCTAAAATTATTTTGGCCGGGCAAGGTGG
GTCACGCCTGTAATCTCAGCACTTTGGGATGCCAAGATGGGTGGATCACCTGAGTTCAGGAGTTCAAGACCAGCTTGGCCAACATGGCGA
AACCCGTCTCTACTAAAGAATACAAAAATTAGCCAGGTGTTGTGGCACATGCCTGTACTCCCAGCTACTCAGGAGGCTGAGGCAGAAGAA
TCATTTGAACCCCGGAGGTGGAGGTTGCAGTGAGCCGACATTGTGCCGCTTCATTCCAGCCTGGGCAACAGAGTGAAACTCTTGTCTCAA
AAGTAAAAAAATAATAATGTTTAAAAATATTTCAATGTGGAGACAAGCTCAAAATGAAATTAGACACATTCCATTACCCAGGTAAAAGAA
GGGGAAGCCTGACTTGATAGTAGTATTCAGGAAAAAAGAGTTGGCAGTTTTATTTGGCCAAATTCCAATATCAGCTCATGGTACAGCACA
CCGGGGGAGGGGGACGGGAGGCGAGAACTAAGGCTTTTTAAGAATGTGTTGATGGAAGTATGTGCCTAGATCAAAAGAATAATCCCCCCG
GACTCCAGTGTAAGATCAATTACTGTTGGAATATTGTGTTCCTTTCTAGATATCACATTTTAAGCAGACTTTGGCCAAGTAGTACAGTGT
TTGCAGGAGCAGTAACAAGATGGTGATAACTTTGAAAATACTTCTCAAAAGAAAAATAAAAAAGAATTAGGGAAGTTCAGTCTGGAGATA
ATTCAGAAATACAGATGATAATTGTTTTCAAATTCTTGAAGGAAATGGGAGAGAGAATAGGCTAATTCTGTATTGCTTCAGAAACCAAAT
GGAAACAATTAAATTCCATTAGAGAAACGGTTGGAAAATATGAGGAGGATTTAGTTCAGTACGAGGAAGCTGTTTCTAATACTTTTTGTT
GGTTAAAAATACATTCCGCTGCTGTGGAAAGCCTGTAGCTGCCAGGAGTGTTACAGAGGGCATTCCTCCCTTGAGTTGACATTTGTGCCA
AACCGGCTTTTAGGGCTTCTCCAGCTTTTAAGATGCGATAATGATAAGATGATCATCGGGAAAACATCCCTCAGATGAAACGTTCACAGG
CTGGCTCTGAAAACTGGCATTCAGATGATTGCGGCTCCCCCATACTGTAGGAATATTGTTTATGGCTTAAGGTTGCCTCGCTCCTCATCT
GTAATCAGTGAAAGTTTATCCAGAGGTTAATTACCGGTTTTCTGGTGGGTATCTGGGAACTGAGGATGGGAGATTAACTGTTGTATATGA
CCATAGTAAAGCAAAAGACTGTTAGAGAATGAGTAAACGTTCGTTTTCCTCCCTACAGAATTTACAGTTACTCTCTGTCCATTCCACTCA
CTACTGTCTTCATCACACACACAGAGGCAAACGTCTGATTCAGATAGCCAGGTGTGCCATGCATGCACTCCACCATATTGTGATCTCTTC
GAGGCTTGTTTCTGTCCCCTGTCCTCCACAGTCCTGGATTGTTAATGAATAGTTCATACATGTTTGTTAAATAAATATACCTTCTTTAAA

>68346_68346_5_PPWD1-NLN_PPWD1_chr5_64875440_ENST00000538977_NLN_chr5_65076006_ENST00000380985_length(amino acids)=885AA_BP=1
MGWTFTCGGNTGQEEERTDFIITASHDGHVKFWKKIEEGIEFVKHFRSHLGVIESIAVSSEGALFCSVGDDKAMKVFDVVNFDMINMLKL
GYFPGQCEWIYCPGDAISSVAASEKSTGKIFIYDGRGDNQPLHIFDKLHTSPLTQIRLNPVYKAVVSSDKSGMIEYWTGPPHEYKFPKNV
NWEYKTDTDLYEFAKCKAYPTSVCFSPDGKKIATIGSDRKVRIFRFVTGKLMRVFDESLSMFTELQQMRQQLPDMEFGRRMAVERELEKV
DAVRLINIVFDETGHFVLYGTMLGIKVINVETNRCVRILGKQENIRVMQLALFQGIAKKHRAATTIEMKASENPVLQNIQADPTIVCTSF
KKNRFYMEIKSMKKRMSELCIDFNKNLNEDDTFLVFSKAELGALPDDFIDSLEKTDDDKYKITLKYPHYFPVMKKCCIPETRRRMEMAFN
TRCKEENTIILQQLLPLRTKVAKLLGYSTHADFVLEMNTAKSTSRVTAFLDDLSQKLKPLGEAEREFILNLKKKECKDRGFEYDGKINAW
DLYYYMTQTEELKYSIDQEFLKEYFPIEVVTEGLLNTYQELLGLSFEQMTDAHVWNKSVTLYTVKDKATGEVLGQFYLDLYPREGKYNHA
ACFGLQPGCLLPDGSRMMAVAALVVNFSQPVAGRPSLLRHDEVRTYFHEFGHVMHQICAQTDFARFSGTNVETDFVEVPSQMLENWVWDV
DSLRRLSKHYKDGSPIADDLLEKLVASRLVNTGLLTLRQIVLSKVDQSLHTNTSLDAASEYAKYCSEILGVAATPGTNMPATFGHLAGGY

--------------------------------------------------------------
>68346_68346_6_PPWD1-NLN_PPWD1_chr5_64875440_ENST00000538977_NLN_chr5_65076006_ENST00000502464_length(transcript)=9184nt_BP=1259nt
GATGCGAACAACATGGCGGCGGAAAGTGGTAGCGATTTTCAGCAGAGACGTAGAAGGCGCCGGGACCCGGAGGAACCGGAAAAAACAGAA
CTCAGCGAAAGAGAGCTGGCAGTAGCAGTGGCGGTGTCCCAGGAGAACGATGAGGAGAACGAAGAGCGCTGGGTTGGACCTTTACCTGTG
GAGGCAACACTGGCCAAGAAGAGGAAAGAACAGATTTTATTATTACTGCCAGTCATGATGGACATGTCAAGTTCTGGAAAAAAATAGAAG
AGGGAATTGAATTTGTTAAACATTTTCGTAGTCACCTGGGAGTTATTGAGAGTATTGCAGTTAGCTCTGAGGGAGCATTGTTCTGTTCTG
TGGGTGATGATAAAGCAATGAAGGTGTTTGATGTAGTGAACTTTGACATGATCAACATGCTGAAACTTGGCTATTTTCCTGGACAGTGTG
AGTGGATCTATTGCCCAGGGGATGCAATTTCTTCAGTTGCTGCTTCCGAAAAGAGTACAGGAAAAATTTTCATTTATGATGGCCGAGGAG
ATAACCAGCCACTTCATATTTTTGACAAACTCCATACATCACCTCTTACTCAGATACGGCTAAACCCAGTTTACAAAGCAGTAGTGTCTT
CTGACAAATCTGGGATGATTGAATACTGGACTGGGCCTCCTCATGAATATAAATTCCCCAAAAATGTGAACTGGGAATATAAAACTGACA
CTGATTTATATGAATTTGCCAAGTGTAAGGCTTATCCAACCAGCGTATGTTTTTCACCAGATGGGAAGAAAATAGCTACTATTGGTTCTG
ATAGAAAAGTTAGAATTTTCAGATTTGTAACTGGAAAACTCATGAGAGTCTTTGATGAATCACTAAGCATGTTTACTGAACTGCAACAGA
TGAGGCAACAGTTACCAGACATGGAATTTGGCCGACGAATGGCTGTAGAACGTGAGTTGGAGAAGGTTGATGCTGTAAGATTAATTAATA
TAGTTTTTGATGAAACTGGACACTTCGTGCTGTATGGAACAATGCTGGGCATTAAAGTTATAAATGTAGAGACAAACCGGTGTGTGCGGA
TTTTAGGCAAACAAGAAAATATTAGAGTGATGCAATTGGCTTTGTTCCAGGGGATAGCCAAAAAGCATCGTGCTGCAACTACTATAGAAA
TGAAAGCTTCTGAAAATCCTGTTCTTCAGAATATTCAAGCTGACCCAACAATAGTCTGTACATCATTCAAAAAGAATAGATTTTATATGG
AAATCAAATCAATGAAGAAAAGAATGAGTGAGCTATGTATTGATTTTAACAAAAACCTCAATGAGGATGATACCTTCCTTGTATTTTCCA
AGGCTGAACTTGGTGCTCTTCCTGATGATTTCATTGACAGTTTAGAAAAGACAGATGATGACAAGTATAAAATTACCTTAAAATATCCAC
ACTATTTCCCTGTCATGAAGAAATGTTGTATCCCTGAAACCAGAAGAAGGATGGAAATGGCTTTTAATACAAGGTGCAAAGAGGAAAACA
CCATAATTTTGCAGCAGCTACTCCCACTGCGAACCAAGGTGGCCAAACTACTCGGTTATAGCACACATGCTGACTTCGTCCTTGAAATGA
ACACTGCAAAGAGCACAAGCCGCGTAACAGCCTTTCTAGATGATTTAAGCCAGAAGTTAAAACCCTTGGGTGAAGCAGAACGAGAGTTTA
TTTTGAATTTGAAGAAAAAGGAATGCAAAGACAGGGGTTTTGAATATGATGGGAAAATCAATGCCTGGGATCTATATTACTACATGACTC
AGACAGAGGAACTCAAGTATTCCATAGACCAAGAGTTCCTCAAGGAATACTTCCCAATTGAGGTGGTCACTGAAGGCTTGCTGAACACCT
ACCAGGAGTTGTTGGGACTTTCATTTGAACAAATGACAGATGCTCATGTTTGGAACAAGAGTGTTACACTTTATACTGTGAAGGATAAAG
CTACAGGAGAAGTATTGGGACAGTTCTATTTGGACCTCTATCCAAGGGAAGGAAAATACAATCATGCGGCCTGCTTCGGTCTCCAGCCTG
GCTGCCTTCTGCCTGATGGAAGCCGGATGATGGCAGTGGCTGCCCTCGTGGTGAACTTCTCACAGCCAGTGGCAGGTCGTCCCTCTCTCC
TGAGACACGACGAGGTGAGGACTTACTTTCATGAGTTTGGTCACGTGATGCATCAGATTTGTGCACAGACTGATTTTGCACGATTTAGCG
GAACAAATGTGGAAACTGACTTTGTAGAGGTGCCATCGCAAATGCTTGAAAATTGGGTGTGGGACGTCGATTCCCTCCGAAGATTGTCAA
AACATTATAAAGATGGAAGCCCTATTGCAGACGATCTGCTTGAAAAACTTGTTGCTTCTAGGCTGGTCAACACAGGTCTTCTGACCCTGC
GCCAGATTGTTTTGAGCAAAGTTGATCAGTCTCTTCATACCAACACATCGCTGGATGCTGCAAGTGAATATGCCAAATACTGCTCAGAAA
TATTAGGAGTTGCAGCTACTCCAGGCACAAATATGCCAGCTACCTTTGGACATTTGGCAGGGGGATACGATGGCCAATATTATGGATATC
TTTGGAGTGAAGTATTTTCCATGGATATGTTTTACAGCTGTTTTAAAAAAGAAGGGATAATGAATCCAGAGGTTGGAATGAAATACAGAA
ACCTAATCCTGAAACCTGGGGGATCTCTGGACGGCATGGACATGCTCCACAATTTCTTGAAACGTGAGCCAAACCAAAAAGCGTTCCTAA
TGAGTAGAGGCCTGCATGCTCCGTGAACTGGGGATCTTTGGTAGCCGTCCATGTCTGGAGGACAAGTCGACATCACCATGTGTTACTGGC
CTGGAAACTGAAGGGAGTTTTGCAAGTGAAAATTTAGATTTCTATTGACATCCTTTTGTTTTCTAATTTTAAAAATTATAAAGATGTAAA
TGGAATTATAAATACTGTGACCTAAGAAAAGACCCACTAGAAAGTAATTGTACTATAAAATTTCATAAAACTGGATTTGATTTCTTTTTA
TGAAAGTTTCATATGAATGTAACTTGATTTTTTACTATTATAATCTAGATAATATGATATAAGAGGGCTAAGAATTTTTAAATTGAATCA
TATATATGATATAATTTGATCCTTCTTGTATCTTGAAGTTTTGTACTTGGGATTTCTGGACTGATAAATGAATCATCACATTCTTCTGGT
AAATATTTTCTTGGAGCTCTGTGTCAACTTTGATCCTTTGTCTCCCAGGAAGGTGTGACCTCTCCTTTGCCTGCATACCTCAAGGCCAGG
GGAATATGCCTCAGTGATGCATTTATCTTTGTATATCAGGCCGCATGATTCCCAACTTTCTGCCACACTTAAATTACGTTCCTCCATTTC
AGTTTTGTCTTTTCTGTCTAAAGTTCAGTCAAAGAGTATCAAAAAATTATGTTTCAGCTAGACTGGTGTAATGTATAAGTTTTTGTATCT
TGTATTAGAGGATTTCGTAGCTTTTATTAGAGGCTCATTTCCACCTCAGCATACAAGATCGTTAGTCTTTTGGCATGTGTGCCAATTAGA
ATACTAAAGCAAGTCCAAGCACATTTTTCTCTTCTCACGTTTCTAATAAGTGTTAGGGACTTTGCCTCTTTTACTTACCACGTCCCCAAA
AGTGTCAGGTAGACATGTCACAAATGGCTCTGTAGAGAGCCATGGGAAGAGAGAGGAGGTGGATGTGGAACATAAAGGGTTCAGAAACTC
CAGAAGAGGAGTGGGTTTTGGATAGAAGCATTTGAGGACAGCTGCTCCAAAGCCTTATGTGTATGATGAAACTTAACCACGGGGAAGAGA
CTCTTCAGTAGCCTGTTCTGTCTGGTGATTTTTATTTTAAGTGAACCTTTGGATCTATCTTTAACTCTCTTTATTGTGAGTCTAAATTCC
AATTCTGCAGCAGATCAGTAAACTCACAGTATTTTTCCTGTGGAAATCTATTCAATAAGGAAACCAAGACAGGATAATAAAATTTAAAAA
AAAAACAACTTTGAATTCCCCTGCCTAGGTCTTCCAGTTGTTTTCCAGCGCATACCTCAGGTATGACTTTGCTAGCCGGGGACAAAATTA
GCACCTTCCGATTCTCTAGTCCAAATGAACTTTGTGCTAAATAAAAAATTATTATACTACATAATAAAGTTACAGATAGCAGGAAATGCA
AGAGCTAGGAGATTCCTAGATTATATCTGCCAAGCAAATACCTTAAACATCCACCTGAAATCCTACTACCCCCTCTTCTGAGATAATTTG
CCCAGCCCTTCTCTTCCCACACACTCACTCAATGTCACCCCCTTCTAATCCCCAAAACTGTTTTTGTGGTCTTTGTAGCCTATAGTAGTT
TTCTCACATCTTTCCCCCTAGACTTTTCTGTTTTTCAGTTTCAGACAAAAAAACTCTTCAGCTTTTTCCAGTGTGTCTCCTTAACAGTAA
CTTTACCACTTGAAATCTTATTTCATAGAAAAACTAAATTGGTGTGGAAAGGCTGCACACAATAAAGTTATATTATTATCCATGAAAATG
AACTCATATTTCTTTCATACTTTAACGTTAAAACCGAAATGCATGAGAGCAAAAGCACCATGGTGTTCTTTCTATTTAGGGCCTACCTCT
AATATTTAAAATCTACCAAAGAGCAGTCACAAAATTAAAACTCAGCCCGGGCGCAGTGGCTCATGCCTGTAATCCCAGCACTTTGGGAGG
CCAAGGCAGGAGGATCACCTGAGGTCAGAGTTCAAGACCAGCATGGTCAACATGGTGAAACCCTGTCTCTACAAAAATACAAAAAGCTGG
GCATGATGTTGGGTTCCTGTAGTCCCAGCTACTTAGGAGGCTGAGGCAGGAGAATAGCTTGAACCCGGGAGGTGGAGGTTGCAGTGAGCT
GAGATCATGCCATTGCACTCCAGCCTGGACGACAGAGTGAGATTCAGTCTCAAAAAAAATTAATACTCAAAGAATTATCTAGCATAATTT
AAAAGAAAGGACTTTTTAAAAATTCTCTAGCATAATTCAAAAGAAAGGACTTAACTTTTTTTTTTTTAGTGTGGTCATCCGTCTAGTTGT
TCTTTTTTTCCAGATCAGAGCAGAGAATATCACTGACATGCTTGAAATGGTGGATAACTATGTAAATTGTAATTGGACAAATGTACACTT
TAGATTTATGGACTGAGCCACATATAATAAGGTCTCTCCTGGTAATTGATCCAGGGGATTTAGGCCTCTTTCGGGTTTTTTGTTTTTTTT
TTAGGCATTGTTATGTTGTGAAGGATAAAATCTTCAACATCTTATGCAAATGGATAGTAGGCATGATCCTAAAGGTTTAGTTTTACGATG
CTGCAGAGAAGAGAAATGTCTTGACGTTTTGCCACCTGATGTAGACTTTGTCCCCCTCTAGTATAAATGTTGCATGTTACCTAGATAAAC
AACTAAAAATTGCCTTGAGTTATCACCTGAGCTACTTATGCCAAGGTCTTGCCTTTCTAAAGCTAATAAGGTGAGAGGTGGATATCTGTA
GCTCTTCGGATGAAAAATTGCATTGTGGGAGATACCAAAATTGAGGAAATAGCTCTTCAAAGAAAAATTACTGATATGATCATTGTACTT
GTAAATGCCTTAAGTAGCAGGCAGTGACTCAATTTTCTACTTTACCATTTTACCTTTAGCTTTTATGTATGAATTATAGGTCTGTGGAGA
TTCTGCCTCCCCACTAGGCCAGTGTGTGTTTACCATTTATTCATTTTCTATCATACACAGGTGGATTAAAATTTACATTAAAATTTACAT
TAAAATACCATCATACTTCAGGCTTCTATAACAAAATATCAGACTGGGTGGCTTCAAAAGCAGACATTTCTTACAGTTCTGGAAGCTGGG
AAGTCCCACAATCCACATGCTGGTAAATTTGGTTCGTGGTGAGGCCCCTCTTCCTCTTTTACTGACCACATCCCCAAAAGTGTCAGGTAG
ACATGTTACAAATAGCTCTGTAGAGAGCCATGGGAAGAGACAGGAGGCAGATGTGGAACATAAAGGGTTTAGAAACTTCTGCAGGCAGCA
GTGGCAGGGAGCAAGCCCTAGAGTGTCTCTTTTTACGAGAGCAGGAATCCCATCATGAGAGTTCCTTCCTCATGACTTTATCTAAACCCA
GTCACCCCCAACAAAGGCCCCACCCCCTAACCCCATCACATTGGCTGTTACGGCTTCAATGTAGGGGATGGGGCACAAACATTCAGTCCA
TAACGAATACTGATTCCTCAAATAGGGTTTAAACATAGTTAACTGAGCCCCCAAAGAATGTTAAAAGAGAAAATCCATTTTATTTGAATA
GATGCAGTGACCACAGCTTCTTCCCTCAAATCAACACATTACAGTTAGATGTCTCCCATCTGAAATTGGATAGCCCACTGAAATTGAACA
TGCCTTCTCTTATAAATGTGTGGTGAGAATAAAAGCAACAAAGAAATGAATGTGGTGGCTCACACCTGTAATCCTAACACTTTGGAAGGT
TGAGGCAGGAGGATCCTTTGTGCTCAAGAGTTTGAGACCAGCCTGAGCAACACAGTGAGACCCTGTCTCTACAAAAACTAAAAAAATTAG
CTAGGGATGGTGGCACATGCCTGTAGTCCCAGCTACTTGGGAGGCTGAGGTGGGAGGATTGCTTGAGCCCAAGAAGGTCAAGGCTGCCAT
GAGCCATAATCACGCCACTGCACTCCAGCCTGGGTGACAGAGACCCTGTCTTAAAATAAAATAAAAAAAAAAGGAAAAGGAAAGACATAC
ATACCCTCAGTTCTTCGAAAAACAGTCAACGTCCAAAAAGTTTATTTTTTGAGTCACCTTTAATAGAGAAATTTCCCACTGGAAACAGAT
CCACCTAAGTGATTATCTAGTATCAGCTGTATCAAGGCAAAAGGTAAAGGTTATAAGATGTAAATATTAGACCAAAATAGCCTTTTTTAA
CAAACACAATAATGCTGTACGTCTGTAACAAAACAAAATTTGAAAAATTGAGGTAATGTACACAGCGATGCACACACCCCCACACCACAC
CGTGATTCCTGAGTTTTGATTTGGTTGAATTCACCTTGTAGTTCCCTTTCCTGAGAAAATACAGGTTCAACACATCTAGTCCACGATGTA
CGTACAAGGGGAAGGGGTGAACAGGAAATAGACTCCCTTATTCTGCTCACATGAGCTGGAACCTGTACTAGCTGCATATTTCATAGACCC
CAGAGGCTCACCTCAATTGTACTCCTATGATAAAATGTCTCTAGCATTTGTCATGAGAGAAACTGGCTAGAAATAGTTTGTTCATTGCGT
CCAGCAAGACACGCATTGCTGTTGATATCTTTGTGGCTAAGATGGAGAATGTGACTGGATAATAGTTATCCAGGTGGATTACTAGCTATT
GAAACAGTCTGAGATAGTTGCATGATGATTAACGTTAAACTGGGAGTAATTTCAAGTCATTTGGCTAAAAATGAAAAAAAAGTCCCATAA
AAAGGTATCAAATGTACAGATAATAGGGCTGGAATTATTAAGTATGATGATGTTATTAACATCTAAAATTATTTTGGCCGGGCAAGGTGG
GTCACGCCTGTAATCTCAGCACTTTGGGATGCCAAGATGGGTGGATCACCTGAGTTCAGGAGTTCAAGACCAGCTTGGCCAACATGGCGA
AACCCGTCTCTACTAAAGAATACAAAAATTAGCCAGGTGTTGTGGCACATGCCTGTACTCCCAGCTACTCAGGAGGCTGAGGCAGAAGAA
TCATTTGAACCCCGGAGGTGGAGGTTGCAGTGAGCCGACATTGTGCCGCTTCATTCCAGCCTGGGCAACAGAGTGAAACTCTTGTCTCAA
AAGTAAAAAAATAATAATGTTTAAAAATATTTCAATGTGGAGACAAGCTCAAAATGAAATTAGACACATTCCATTACCCAGGTAAAAGAA
GGGGAAGCCTGACTTGATAGTAGTATTCAGGAAAAAAGAGTTGGCAGTTTTATTTGGCCAAATTCCAATATCAGCTCATGGTACAGCACA
CCGGGGGAGGGGGACGGGAGGCGAGAACTAAGGCTTTTTAAGAATGTGTTGATGGAAGTATGTGCCTAGATCAAAAGAATAATCCCCCCG
GACTCCAGTGTAAGATCAATTACTGTTGGAATATTGTGTTCCTTTCTAGATATCACATTTTAAGCAGACTTTGGCCAAGTAGTACAGTGT
TTGCAGGAGCAGTAACAAGATGGTGATAACTTTGAAAATACTTCTCAAAAGAAAAATAAAAAAGAATTAGGGAAGTTCAGTCTGGAGATA
ATTCAGAAATACAGATGATAATTGTTTTCAAATTCTTGAAGGAAATGGGAGAGAGAATAGGCTAATTCTGTATTGCTTCAGAAACCAAAT
GGAAACAATTAAATTCCATTAGAGAAACGGTTGGAAAATATGAGGAGGATTTAGTTCAGTACGAGGAAGCTGTTTCTAATACTTTTTGTT
GGTTAAAAATACATTCCGCTGCTGTGGAAAGCCTGTAGCTGCCAGGAGTGTTACAGAGGGCATTCCTCCCTTGAGTTGACATTTGTGCCA
AACCGGCTTTTAGGGCTTCTCCAGCTTTTAAGATGCGATAATGATAAGATGATCATCGGGAAAACATCCCTCAGATGAAACGTTCACAGG
CTGGCTCTGAAAACTGGCATTCAGATGATTGCGGCTCCCCCATACTGTAGGAATATTGTTTATGGCTTAAGGTTGCCTCGCTCCTCATCT
GTAATCAGTGAAAGTTTATCCAGAGGTTAATTACCGGTTTTCTGGTGGGTATCTGGGAACTGAGGATGGGAGATTAACTGTTGTATATGA
CCATAGTAAAGCAAAAGACTGTTAGAGAATGAGTAAACGTTCGTTTTCCTCCCTACAGAATTTACAGTTACTCTCTGTCCATTCCACTCA
CTACTGTCTTCATCACACACACAGAGGCAAACGTCTGATTCAGATAGCCAGGTGTGCCATGCATGCACTCCACCATATTGTGATCTCTTC
GAGGCTTGTTTCTGTCCCCTGTCCTCCACAGTCCTGGATTGTTAATGAATAGTTCATACATGTTTGTTAAATAAATATACCTTCTTTAAA

>68346_68346_6_PPWD1-NLN_PPWD1_chr5_64875440_ENST00000538977_NLN_chr5_65076006_ENST00000502464_length(amino acids)=885AA_BP=1
MGWTFTCGGNTGQEEERTDFIITASHDGHVKFWKKIEEGIEFVKHFRSHLGVIESIAVSSEGALFCSVGDDKAMKVFDVVNFDMINMLKL
GYFPGQCEWIYCPGDAISSVAASEKSTGKIFIYDGRGDNQPLHIFDKLHTSPLTQIRLNPVYKAVVSSDKSGMIEYWTGPPHEYKFPKNV
NWEYKTDTDLYEFAKCKAYPTSVCFSPDGKKIATIGSDRKVRIFRFVTGKLMRVFDESLSMFTELQQMRQQLPDMEFGRRMAVERELEKV
DAVRLINIVFDETGHFVLYGTMLGIKVINVETNRCVRILGKQENIRVMQLALFQGIAKKHRAATTIEMKASENPVLQNIQADPTIVCTSF
KKNRFYMEIKSMKKRMSELCIDFNKNLNEDDTFLVFSKAELGALPDDFIDSLEKTDDDKYKITLKYPHYFPVMKKCCIPETRRRMEMAFN
TRCKEENTIILQQLLPLRTKVAKLLGYSTHADFVLEMNTAKSTSRVTAFLDDLSQKLKPLGEAEREFILNLKKKECKDRGFEYDGKINAW
DLYYYMTQTEELKYSIDQEFLKEYFPIEVVTEGLLNTYQELLGLSFEQMTDAHVWNKSVTLYTVKDKATGEVLGQFYLDLYPREGKYNHA
ACFGLQPGCLLPDGSRMMAVAALVVNFSQPVAGRPSLLRHDEVRTYFHEFGHVMHQICAQTDFARFSGTNVETDFVEVPSQMLENWVWDV
DSLRRLSKHYKDGSPIADDLLEKLVASRLVNTGLLTLRQIVLSKVDQSLHTNTSLDAASEYAKYCSEILGVAATPGTNMPATFGHLAGGY

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Fusion Gene PPI Analysis for PPWD1-NLN


check button Go to ChiPPI (Chimeric Protein-Protein interactions) to see the chimeric PPI interaction in

ChiPPI page.


check button Protein-protein interactors with each fusion partner protein in wild-type (BIOGRID-3.4.160)
HgeneHgene's interactorsTgeneTgene's interactors


check button - Retained PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenStill interaction with


check button - Lost PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


check button - Retained PPIs, but lost function due to frame-shift fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


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Related Drugs for PPWD1-NLN


check button Drugs targeting genes involved in this fusion gene.
(DrugBank Version 5.1.8 2021-05-08)
PartnerGeneUniProtAccDrugBank IDDrug nameDrug activityDrug typeDrug status

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Related Diseases for PPWD1-NLN


check button Diseases associated with fusion partners.
(DisGeNet 4.0)
PartnerGeneDisease IDDisease name# pubmedsSource