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Center for Computational Systems Medicine
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Fusion Gene Summary

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Fusion Gene ORF analysis

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Fusion Genomic Features

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Fusion Protein Features

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Fusion Gene Sequence

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Fusion Gene PPI analysis

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Related Drugs

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Related Diseases

Fusion gene:ARRDC2-PRRC2B (FusionGDB2 ID:6864)

Fusion Gene Summary for ARRDC2-PRRC2B

check button Fusion gene summary
Fusion gene informationFusion gene name: ARRDC2-PRRC2B
Fusion gene ID: 6864
HgeneTgene
Gene symbol

ARRDC2

PRRC2B

Gene ID

27106

84726

Gene namearrestin domain containing 2proline rich coiled-coil 2B
SynonymsCLONE24945|PP2703BAT2L|BAT2L1|KIAA0515|LQFBS-1
Cytomap

19p13.11

9q34.13

Type of geneprotein-codingprotein-coding
Descriptionarrestin domain-containing protein 2protein PRRC2BHLA-B associated transcript 2-likeHLA-B-associated transcript 2-like 1proline-rich coiled-coil protein 2Bprotein BAT2-like 1
Modification date2020031320200313
UniProtAcc

Q8TBH0

.
Ensembl transtripts involved in fusion geneENST00000379656, ENST00000222250, 
ENST00000608009, 		ENST00000372249, 
ENST00000465931, ENST00000357304, 
ENST00000405995, ENST00000458550, 
Fusion gene scores* DoF score7 X 3 X 3=6310 X 9 X 5=450
# samples 711
** MAII scorelog2(7/63*10)=0.15200309344505
effective Gene in Pan-Cancer Fusion Genes (eGinPCFGs).
DoF>8 and MAII>0		log2(11/450*10)=-2.03242147769238
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0
Context

PubMed: ARRDC2 [Title/Abstract] AND PRRC2B [Title/Abstract] AND fusion [Title/Abstract]

Most frequent breakpointARRDC2(18112382)-PRRC2B(134353861), # samples:1
Anticipated loss of major functional domain due to fusion event.
* DoF score (Degree of Frequency) = # partners X # break points X # cancer types
** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10)

check button Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez
PartnerGeneGO IDGO termPubMed ID

check buttonFusion gene breakpoints across ARRDC2 (5'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.
all structure

check buttonFusion gene breakpoints across PRRC2B (3'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.
all structure

check button Fusion gene information from two resources (ChiTars 5.0 and ChimerDB 4.0)
* All genome coordinats were lifted-over on hg19.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
SourceDiseaseSampleHgeneHchrHbpHstrandTgeneTchrTbpTstrand
ChimerDB4STADTCGA-HU-A4GN-01AARRDC2chr19

18112382

+PRRC2Bchr9

134353861

+


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Fusion Gene ORF analysis for ARRDC2-PRRC2B

check button Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
ORFHenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrand
5CDS-5UTRENST00000379656ENST00000372249ARRDC2chr19

18112382

+PRRC2Bchr9

134353861

+
5CDS-intronENST00000379656ENST00000465931ARRDC2chr19

18112382

+PRRC2Bchr9

134353861

+
In-frameENST00000379656ENST00000357304ARRDC2chr19

18112382

+PRRC2Bchr9

134353861

+
In-frameENST00000379656ENST00000405995ARRDC2chr19

18112382

+PRRC2Bchr9

134353861

+
In-frameENST00000379656ENST00000458550ARRDC2chr19

18112382

+PRRC2Bchr9

134353861

+
intron-3CDSENST00000222250ENST00000357304ARRDC2chr19

18112382

+PRRC2Bchr9

134353861

+
intron-3CDSENST00000222250ENST00000405995ARRDC2chr19

18112382

+PRRC2Bchr9

134353861

+
intron-3CDSENST00000222250ENST00000458550ARRDC2chr19

18112382

+PRRC2Bchr9

134353861

+
intron-3CDSENST00000608009ENST00000357304ARRDC2chr19

18112382

+PRRC2Bchr9

134353861

+
intron-3CDSENST00000608009ENST00000405995ARRDC2chr19

18112382

+PRRC2Bchr9

134353861

+
intron-3CDSENST00000608009ENST00000458550ARRDC2chr19

18112382

+PRRC2Bchr9

134353861

+
intron-5UTRENST00000222250ENST00000372249ARRDC2chr19

18112382

+PRRC2Bchr9

134353861

+
intron-5UTRENST00000608009ENST00000372249ARRDC2chr19

18112382

+PRRC2Bchr9

134353861

+
intron-intronENST00000222250ENST00000465931ARRDC2chr19

18112382

+PRRC2Bchr9

134353861

+
intron-intronENST00000608009ENST00000465931ARRDC2chr19

18112382

+PRRC2Bchr9

134353861

+

check buttonORFfinder result based on the fusion transcript sequence of in-frame fusion genes.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandSeq length
(transcript)		BP loci
(transcript)		Predicted start
(transcript)		Predicted stop
(transcript)		Seq length
(amino acids)
ENST00000379656ARRDC2chr1918112382+ENST00000405995PRRC2Bchr9134353861+6843442782519813
ENST00000379656ARRDC2chr1918112382+ENST00000357304PRRC2Bchr9134353861+6817442782519813
ENST00000379656ARRDC2chr1918112382+ENST00000458550PRRC2Bchr9134353861+2969442782519813

check buttonDeepORF prediction of the coding potential based on the fusion transcript sequence of in-frame fusion genes. DeepORF is a coding potential classifier based on convolutional neural network by comparing the real Ribo-seq data. If the no-coding score < 0.5 and coding score > 0.5, then the in-frame fusion transcript is predicted as being likely translated.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandNo-coding scoreCoding score
ENST00000379656ENST00000405995ARRDC2chr1918112382+PRRC2Bchr9134353861+0.0015798220.99842024
ENST00000379656ENST00000357304ARRDC2chr1918112382+PRRC2Bchr9134353861+0.0017578630.99824214
ENST00000379656ENST00000458550ARRDC2chr1918112382+PRRC2Bchr9134353861+0.012582130.98741794

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Fusion Genomic Features for ARRDC2-PRRC2B


check buttonFusionAI prediction of the potential fusion gene breakpoint based on the pre-mature RNA sequence context (+/- 5kb of individual partner genes, total 20kb length sequence). FusionAI is a fusion gene breakpoint classifier based on convolutional neural network by comparing the fusion positive and negative sequence context of ~ 20K fusion gene data. From here, we can have the relative potentency of the 20K genomic sequence how individual sequnce will be likely used as the gene fusion breakpoints.
HgeneHchrHbpHstrandTgeneTchrTbpTstrand1-pp (fusion gene breakpoint)
ARRDC2chr1918112382+PRRC2Bchr9134353860+9.46E-080.9999999
ARRDC2chr1918112382+PRRC2Bchr9134353860+9.46E-080.9999999

check buttonDistribution of 44 human genomic features loci across 20kb length fusion breakpoint regions. We integrated a total of 44 different types of human genomic feature loci information across five big categories including virus integration sites, repeats, structural variants, chromatin states, and gene expression regulation. More details are in help page.
genomic feature

check buttonDistribution of 44 human genomic features loci across 20kb length fusion breakpoint regions that are ovelapped with the top 1% feature importance score regions. More details are in help page.
genomic feature of top 1%

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Fusion Protein Features for ARRDC2-PRRC2B


check button Four levels of functional features of fusion genes
Go to FGviewer search page for the most frequent breakpoint (https://ccsmweb.uth.edu/FGviewer/chr19:18112382/chr9:134353861)
- FGviewer provides the online visualization of the retention search of the protein functional features across DNA, RNA, protein, and pathological levels.
- How to search
1. Put your fusion gene symbol.
2. Press the tab key until there will be shown the breakpoint information filled.
4. Go down and press 'Search' tab twice.
4. Go down to have the hyperlink of the search result.
5. Click the hyperlink.
6. See the FGviewer result for your fusion gene.
FGviewer

check buttonMain function of each fusion partner protein. (from UniProt)
HgeneTgene
ARRDC2

Q8TBH0

.
FUNCTION: Transcriptional activator which is required for calcium-dependent dendritic growth and branching in cortical neurons. Recruits CREB-binding protein (CREBBP) to nuclear bodies. Component of the CREST-BRG1 complex, a multiprotein complex that regulates promoter activation by orchestrating a calcium-dependent release of a repressor complex and a recruitment of an activator complex. In resting neurons, transcription of the c-FOS promoter is inhibited by BRG1-dependent recruitment of a phospho-RB1-HDAC1 repressor complex. Upon calcium influx, RB1 is dephosphorylated by calcineurin, which leads to release of the repressor complex. At the same time, there is increased recruitment of CREBBP to the promoter by a CREST-dependent mechanism, which leads to transcriptional activation. The CREST-BRG1 complex also binds to the NR2B promoter, and activity-dependent induction of NR2B expression involves a release of HDAC1 and recruitment of CREBBP (By similarity). {ECO:0000250}.

check buttonRetention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at

download page


* Minus value of BPloci means that the break pointn is located before the CDS.
- In-frame and retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
TgenePRRC2Bchr19:18112382chr9:134353861ENST0000035730415311563_158715372230.0Coiled coilOntology_term=ECO:0000255
TgenePRRC2Bchr19:18112382chr9:134353861ENST000003722499241563_15870269.0Coiled coilOntology_term=ECO:0000255
TgenePRRC2Bchr19:18112382chr9:134353861ENST00000372249924495_5530269.0Coiled coilOntology_term=ECO:0000255
TgenePRRC2Bchr19:18112382chr9:134353861ENST0000040599515311563_15878431536.0Coiled coilOntology_term=ECO:0000255
TgenePRRC2Bchr19:18112382chr9:134353861ENST0000045855014301563_15878431536.0Coiled coilOntology_term=ECO:0000255
TgenePRRC2Bchr19:18112382chr9:134353861ENST0000035730415311953_195615372230.0Compositional biasNote=Poly-Ala
TgenePRRC2Bchr19:18112382chr9:134353861ENST000003722499241953_19560269.0Compositional biasNote=Poly-Ala
TgenePRRC2Bchr19:18112382chr9:134353861ENST00000372249924391_3950269.0Compositional biasNote=Poly-Glu
TgenePRRC2Bchr19:18112382chr9:134353861ENST00000372249924616_6470269.0Compositional biasNote=Gln-rich
TgenePRRC2Bchr19:18112382chr9:134353861ENST0000040599515311953_19568431536.0Compositional biasNote=Poly-Ala
TgenePRRC2Bchr19:18112382chr9:134353861ENST0000045855014301953_19568431536.0Compositional biasNote=Poly-Ala

- In-frame and not-retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
TgenePRRC2Bchr19:18112382chr9:134353861ENST000003573041531495_55315372230.0Coiled coilOntology_term=ECO:0000255
TgenePRRC2Bchr19:18112382chr9:134353861ENST000004059951531495_5538431536.0Coiled coilOntology_term=ECO:0000255
TgenePRRC2Bchr19:18112382chr9:134353861ENST000004585501430495_5538431536.0Coiled coilOntology_term=ECO:0000255
TgenePRRC2Bchr19:18112382chr9:134353861ENST000003573041531391_39515372230.0Compositional biasNote=Poly-Glu
TgenePRRC2Bchr19:18112382chr9:134353861ENST000003573041531616_64715372230.0Compositional biasNote=Gln-rich
TgenePRRC2Bchr19:18112382chr9:134353861ENST000004059951531391_3958431536.0Compositional biasNote=Poly-Glu
TgenePRRC2Bchr19:18112382chr9:134353861ENST000004059951531616_6478431536.0Compositional biasNote=Gln-rich
TgenePRRC2Bchr19:18112382chr9:134353861ENST000004585501430391_3958431536.0Compositional biasNote=Poly-Glu
TgenePRRC2Bchr19:18112382chr9:134353861ENST000004585501430616_6478431536.0Compositional biasNote=Gln-rich


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Fusion Gene Sequence for ARRDC2-PRRC2B


check button For in-frame fusion transcripts, we provide the fusion transcript sequences and fusion amino acid sequences. To have fusion amino acid sequence, we ran ORFfinder and chose the longest ORF among the all predicted ones.
>6864_6864_1_ARRDC2-PRRC2B_ARRDC2_chr19_18112382_ENST00000379656_PRRC2B_chr9_134353861_ENST00000357304_length(transcript)=6817nt_BP=442nt
CCAGGAAGTTCGCCGACGACGCGCCCGCCCTGGGCCACCGGCGCCGGCCCAAGTTCGCCGGGGGGGCCCGGAGGAAGCTTGGGGGACGCG
ACGGGGGAACGCGGAAACCCCGGGGATCTGCAGGCGCGCCCGGGCCGTGTGCCTTCTCTCCGCGTGTCCAAACCGTGTCCCCAGCCGCGC
GCCATGCGCTCTGGGGGCGTGCGCAGCTTCGCGCTGGAGCTGGCGCGGGGCCCGGGCGGCGCCTACCGCGGCGGGGAGCGGCTGTGCGGC
CGGGTGCTGCTGGAGGCGGCGGCGCCGCTGCGGGTGCGAGCGCTCGAGGTGAAGGCGCGCGGCGGGGCGGCCACCCACTGGTTGGAGGGT
CGCAGCGTGGGCGTCAACGCCGTATCCAGCGACTACGCGGCCGCGGAGACCTACCTGCGGCGTCGGCAGCTGCTGCTCCGAGGTGCCATC
ATTGAAAATTGCGGGTCCAGCCCCGGGGAGGAGAGTGAGGTGGGTTCTATGGTGGGCGAAGGCTTCATCGAAGTCCTGACCAAGAAGCAG
CGCCGCCTGCTGGAGGAAGAGAGAAGAAAGAAGGAGCAGGCCGTGCAGGTGCCTGTCAAAGGTCGAGGCCTTTCCTCCCGTATTCCTCCT
CGATTTGCAAAAAAGCAGAACAACTTATGTCTGGAGCAAGGTGACGTGACCGTGCCTGGCAGCAGCCTGGGCACTGAGATCTGGGAGAGC
AGCAGCCAGGCTCTCCCTGTGCAGGCCCCAGCCAACGACTCCTGGAGGAAAGCTGTCACTGCCTTCAGCAGCACCGAGACTGGCTCTGCG
GAGCAGGGTTTTAAGAGCAGCCAGGGAGATAGTGGCGTTGACTTGAGTGCCGAGTCTCGGGAGTCGTCTGCGACCTCCTCGCAGCGCAGC
TCCCCATATGGGACTCTGAAGCCAGAGGAGATGAGCGGGCCCGGCCTGGCGGAACCCAAGGCCGACAGCCACAAGGAGCAGGCTCCAAAG
CCATCTGAGCAGAAGGATTCAGAACAAGGCTCTGGACAGAGCAAGGAGCACAGACCAGGACCCATCGGCAACGAGCGTTCTCTGAAAAAC
AGAAAGGGCTCGGAGGGGGCCGAGCGGCTGCAAGGGGCTGTCGTCCCGCCTGTTAACGGGGTGGAGATTCACGTGGACTCCGTGCTGCCT
GTGCCACCCATTGAATTTGGAGTCAGTCCAAAAGACTCCGATTTCAGCTTGCCACCTGGTTCTGCCTCTGGTCCTACTGGGAGTCCAGTT
GTTAAACTTCAGGATGCCTTGGCCAGTAATGCAGGGTTAACACAGAGTATCCCCATCCTGCGGCGGGACCATCACATCCAGAGGGCCATC
GGTCTCTCCCCAATGTCCTTCCCCACCGCCGACCTTACTCTGAAGATGGAGTCTGCGCGCAAGGCTTGGGAAAACTCCCCCAGTTTGCCG
GAGCAGAGCTCTCCAGGCGGCGCTGGCTCAGGCATCCAGCCTCCATCCTCTGTGGGTGCCTCCAGCGGGGTCAACTACAGCTCCTTCGGT
GGAGTGTCCATGCCACCCATGCCTGTGGCCTCTGTAGCACCTTCTGCTTCTATGCCAGGCAGCCACCTCCCGCCCCTGTACCTGGATGGC
CATGTGTTTGCAAGTCAGCCCCGGCTGGTTCCTCAAACGATACCTCAGCAGCAGAGTTACCAACAGGCCGCCGCTGCCCAGCAGATCCCG
ATCTCCCTTCACACATCTCTGCAGGCACAAGCTCAGCTTGGACTGAGGGGTGGGCTTCCTGTGTCCCAGTCCCAGGAGATCTTCAGCTCC
TTGCAGCCCTTCAGATCTCAGGTGTACATGCACCCCAGCCTGTCACCGCCCAGCACCATGATCCTCTCTGGGGGCACAGCCTTGAAGCCT
CCATACTCGGCGTTCCCAGGCATGCAGCCCTTGGAGATGGTGAAGCCGCAGTCTGGCTCACCCTACCAGCCCATGAGCGGGAACCAAGCC
CTGGTCTACGAGGGCCAGCTCAGCCAGGCTGCTGGCCTGGGTGCCTCCCAGATGTTGGACTCCCAGCTCCCACAGCTGACCATGCCACTG
CCTCGGTACGGCTCCGGGCAGCAGCCACTGATCCTGCCCCAGTCTATTCAGCTGCCACCTGGGCAGAGCCTCTCCGTTGGGGCCCCCCGA
AGGATTCCTCCGCCCGGGTCCCAGCCGCCAGTCCTGAACACCAGCAGAGAGCCCTCTCAGATGGAGATGAAAGGCTTCCACTTTGCCGAC
AGTAAACAGAATGTCCCTTCAGGAGGCCCCGTGCCATCGCCACAGACCTACAGGCCTAGCTCTGCTAGCCCCAGTGGGAAGCCCTCTGGA
TCAGCAGTTAACATGGGCTCTGTGCAGGGACACTACGTGCAACAGGCAAAACAACGAGTGGATGAGAAACCCAGCCTGGGAGCCGTGAAG
CTGCAGGAGGCCCCCTCGGCTGCCTCCCAGATGAAGCGAACCGGAGCGATCAAGCCTCGGGCTGTCAAAGTGGAGGAGAGTAAGGCCTGA
CAGTGCCTGGCTGCCACCTCGCCTCTCCCTACTGAGGACGGTGCCGCCATGCGGCCTCGACACAGCCGACACTCGGGAGCCTCACCAGAT
CCACCGTCCAAATGCGTGGCCCAGACTGAGAGACCTCCCTCCTCTCCACTCCCGAAAGCTCCGTTGTCAACCAGCTTGCACCCGTGGATA
TATGGCATTGACCCGCTTGCTTTGATACGAAACAAAAAAGCAGACGACTCCTTCATCCCATCTGCTCCTACCGTGACTGTGGAGTGACGC
CTCCTGTGCAGTGCAGATTTGCCCTCCCTGCCTCCTCCCTGTCCTGCCGCGCAGCCAGGGCGCCTTCTCAGCAGTGCTTCCGGCCCAGCC
GCCCATCCCTAGGCACAGTGATTTGGCAGCAGGGTCATTTTACTTTGAGGCTTTTTGTTTTAAAATGTAGCCAAGGTTTTTACAAAGGGG
AAAGGAAAAGAAAACAAAAACGCAAGCTCCATGTGTATAGCTGAACTTTTATATGTTTCTTGCCAGCCCCTCCGCTCCCTTCCATCTCTA
GCCTCTGTCCTGTTTAGTTTGATACGTCACTGCAGTACCTTAAGAGGTGACTCTTAAGAATGCATCCCCTCCTGATTCCTCAGCTGGTTC
ACCCTTGAGGTTATTTGCAAAAAGAAAAGGAGGTTCTTGAGGGCACCGATTGCGAGCATTCTGGTGCCTGGCTCCCCGCCTGGGAAGCGA
TGGGGTGCTCAGAGCAGCAGGCAGGTTGGGGGAGGGGGGGGGTCATAGTTGGGTTCCAGCTCCTGGCTTGATGAGCCCAGGGCGCTTACA
GGCAGCCCATGAAGTTGATGACAGTTTTAGCATGAGAATCACACAGGGTCCCTGTCCTGGGCTCCTCTAAAGCCAGTGGATGTGCTGGGC
ACCAGAGACAAATCATGGAGATGGCTGCTGGTGGCTCCCAGGTTGGCCCAGATGGGGTGAGCTGACATACCACAGGCCCATCCCAGGCCC
CGTGGGCTCTGCTTCTGGGGCTCCATACCCTGCCCTGCAGGGGTGCTGTGTTTTTCACACATTTCTTTCCCTGAAGCCTTCTGTAACCTG
TCATTTTCCTTCCTTCCTCTTCCGGAGCCTGCTGCTTTCTCTGGACCTGTCTCCACCTCCCACACAGCTCATCGTGAACACCACTTGGTG
ATGGAGGGAGTGGACCCGTGTGTGGTCCCCAAGTGAGGCCACTGGGAGTTTGTCCTTTTCCTCCTTTGCTTCACTCCCAGCAGCAGACCC
AGGTTGTCAGGACAGGAGGGCCTGAGCTAAGCAGTAGGCATCAGTCTCGTTTGTCTTCAGACGGCGGGGGCAGGTCCAGGGTGAGGCTGG
GTGGAGGGCTGACCAAGGTCCAAAGGGCCTGCGCAGCCTCCGGGAGGGCAGCTTCTCCAGCCAGAGGCTTGTGTGAGCCATCGTGTGCTG
GGCTTGTTTTTAAGTAAGAAACAAGGAAATCACTCCAGATTCTGTCATTCCAAGGAAAGGGAAGGGGACAGTTCAGGTTTCTCAGCTGTT
CTTAGGGGTCACTGAGCGTCTACCTCCTCCTCCAGAGGAGGCTGGCTCAGAACACCTAGAGGAGGGGGCCGGGGATGCACCCCCCACCAG
AGGCTGCCTTCAGCGTCTCACGGGTGCAGGACAGCGCTCAGGCTTGGGCTCTAAGCTCTGTGTCTAGTGTAGAACATGGGGAAGGAGCAT
CTTAGGAACTGCTGAAGTAACTTCTTACTGCTCTCACAATTCTAAGGAAGCGGGAGAACGGCCTCCTACCAACAGCGCCCACCCCAGAGC
TGCCTGGGAAAGGGCAGTTTTACTGAAAGGTGCTTTACTGTTCACCTGCATCTTTCAGCAGCTCCCCTCCTGCCCTCACCTGGTCTTTTC
CCTCTTTATCCCAAGCCTTTATGCTTGAGTCCCTTCCCCAGGGGCTGCCCACCCGACAGTTCCAGGCATTCCCTACCTGAGCTTCTTGTC
TGCTTTTCCTTCTCCCACTGCAAGCGGCTGCTTGTGGGGCCTGGGATGAGCCCTCTCTGTCCCCACCGGCCCTCCTTGCCAAGCCATTCC
TGGGTGAGTTCAGGCCTGCGGGAGCCACACATTCATCTCCACCTGGACACTTGAGCCGCATGGCCAGACCCCTCCCACCTGATGCGGTGG
TGCGTGTGATTTGTCAAAAGAAAGCCTTCTGGATGCTGTTAAGATGTACCCTTCAGGTGAACCTGGTATCAGACCCACAGTACTTGCTGT
TTGAGAAAAAATAAAAACAAAAAGGTCACCTGTTCTCCAGCCCTTTTCTCTTACCTGGTATTTCCTTCCTTTCTCCTCCCCCACCCCAAA
TAAAAAAACAAAAAACACTAGAATTTATTTATATGTATTGATGTTGTAGGTCTAGGTGAAAAAAAAAGAAGTAAATGTTTCACTGCTCTA
TTTATATATAATGTCTGAATTAATTCTGTGCAGGAAAGGCCAGGAAATTGCATGTGAAGTTCGGTGCAGTCACCACCTGTGTGTGACCTG
AGCTGCAGTCTCTTCGCTGAGATGCAGGTTTTAAATGAGACTTGGGGGGCTGAGGGCAGGCCTCAGGCCTCCCAGCGCCCCAACCCCTCC
TTGGTCTAATGAAATGCAGTTCTTAGTGCAGAGATGTTTTAAGGTGCAATATATCTCTTCCTTTCCCGTGGTTTTAGAGCCAAGCTCAAG
GTAGTAGGACGTAGGGTCTTATTTTGTTTTCAAACCCCCATCCTCAGAGCGCAGATACATGCAGAGGCTTCTGCCAGGATACCACGGGGC
CTTAGTGGGAACAGGTGGAGACCAGCACTTCCCTTTCCTGCTGCTGAGGTAGGGATTGGGGGGTCAGAACCCACTCACTTTTGCCTGTTA
AAGTTGCCCTCCTGACGCTGGCAGCTCTGCCTTGGTCACTGGGGATGCGGCTCGTTGCTCAGCCACCAGTGGCCTTGCGGTATTGTCCAC
CATCCACTAGAGTGGGATGAAGTCCAGAGTGTGGGTATACATCTCAGATGCCCATCTACCCACTGGGGACTTCAATGCCAGCTGCATTTG
GTTTGGTTTTCTTAACTGTTGGCTTCTCCCCACAGCGTTTTTTGTTTTTTTTTAAACATTCATATTGTTTTCAAACTTGGAATTCATAGA
CACTCTGGCTCTAGGTTCCTTAAGGGGGAAAACAAAAGATGACTTTATTTCACATTCAAGAAAATCAGTTCAGTTCCAAAGCTGTGGTCC
TTCCAGCCACTTCTAGGGACACTGGGGAACCTTGTTAAACGTTGACATCAGTGCTCTCCAGCCGTGCTGTCACCCTCCTATCTTCTGGAT
CTGCCTTCGCGATGGTCAGTGACAGCTTCTGGAAGCTGAGCACACACAGGTGCACAGCCATGCTGTGGTCTGGCCTGCTACGGCAGCATG
GCAGCTCTGGTGGAGCCTTCTCCCTTGCCATTTGGTTCCCCTGTGCCAAGTAGCTGCAGGCTGCCCCTCAAATCTTCATTTGTCCCTTTT
CACTTCCTGCAGAACAAGCCTGGGTTAGAGGGTCTGCTGGAAATGGCCTTTGAAGACCAAGGATACCAGGATGTGTGCACTCTGTCGTGT
TCTGTGATGAATGGGAAACGTAGGCTTCCAGAAAGCCAGCTCTCTTCTGAAATGTGACGGACCTAAGCAGGAAGTCATCCAGGACAGGAG
TGGCTCAGTGTTGGGGATGGACGCTGTCGCCCAGCCATGCTCCACCAGGGCCACCAATGTGTAGTTGGCTGGTGGTCTTCGGGCATGTGA
GACCTGCTCTTCACTGTTTCCACCCCACTTGGTGGCCTCCAGGATGGTAGTGGCACCCTCAGAGCCCCATCTTCAGCATGTTCTGAAGCC
TCAGAGTGGAAATTCCTGCTAAGGCTCTGTGTGGACGCCTTTCTCCCGTGATCTAAAGGGGACACTGTACTCAAGCTTTTGACCTCATGC
CTTGTGTAGTAAAAAAGGATTTGGGGGTTTTGTTTGGTTCCTGAGAGGGTTGTGTTTTGTTTTTGTTTCCTTTTGTTTATGTTTTGGCCT
TTCCTCTTTGTCTTTCCATGTAGACCAGATATTTGAAAGGGCAGACGATGGCTAGAGGTGTAATGTGCAGCTTGTTTATACGGTATTTTG
GGAAACTTACCTTGGATGGGAAATCGAATCGTGGATTCACCAGGCCGGTGCTGGCACACTCACCCTCGCCCTTTCCCTCCGGTTCAGTAC

>6864_6864_1_ARRDC2-PRRC2B_ARRDC2_chr19_18112382_ENST00000379656_PRRC2B_chr9_134353861_ENST00000357304_length(amino acids)=813AA_BP=121
MGDATGERGNPGDLQARPGRVPSLRVSKPCPQPRAMRSGGVRSFALELARGPGGAYRGGERLCGRVLLEAAAPLRVRALEVKARGGAATH
WLEGRSVGVNAVSSDYAAAETYLRRRQLLLRGAIIENCGSSPGEESEVGSMVGEGFIEVLTKKQRRLLEEERRKKEQAVQVPVKGRGLSS
RIPPRFAKKQNNLCLEQGDVTVPGSSLGTEIWESSSQALPVQAPANDSWRKAVTAFSSTETGSAEQGFKSSQGDSGVDLSAESRESSATS
SQRSSPYGTLKPEEMSGPGLAEPKADSHKEQAPKPSEQKDSEQGSGQSKEHRPGPIGNERSLKNRKGSEGAERLQGAVVPPVNGVEIHVD
SVLPVPPIEFGVSPKDSDFSLPPGSASGPTGSPVVKLQDALASNAGLTQSIPILRRDHHIQRAIGLSPMSFPTADLTLKMESARKAWENS
PSLPEQSSPGGAGSGIQPPSSVGASSGVNYSSFGGVSMPPMPVASVAPSASMPGSHLPPLYLDGHVFASQPRLVPQTIPQQQSYQQAAAA
QQIPISLHTSLQAQAQLGLRGGLPVSQSQEIFSSLQPFRSQVYMHPSLSPPSTMILSGGTALKPPYSAFPGMQPLEMVKPQSGSPYQPMS
GNQALVYEGQLSQAAGLGASQMLDSQLPQLTMPLPRYGSGQQPLILPQSIQLPPGQSLSVGAPRRIPPPGSQPPVLNTSREPSQMEMKGF
HFADSKQNVPSGGPVPSPQTYRPSSASPSGKPSGSAVNMGSVQGHYVQQAKQRVDEKPSLGAVKLQEAPSAASQMKRTGAIKPRAVKVEE

--------------------------------------------------------------
>6864_6864_2_ARRDC2-PRRC2B_ARRDC2_chr19_18112382_ENST00000379656_PRRC2B_chr9_134353861_ENST00000405995_length(transcript)=6843nt_BP=442nt
CCAGGAAGTTCGCCGACGACGCGCCCGCCCTGGGCCACCGGCGCCGGCCCAAGTTCGCCGGGGGGGCCCGGAGGAAGCTTGGGGGACGCG
ACGGGGGAACGCGGAAACCCCGGGGATCTGCAGGCGCGCCCGGGCCGTGTGCCTTCTCTCCGCGTGTCCAAACCGTGTCCCCAGCCGCGC
GCCATGCGCTCTGGGGGCGTGCGCAGCTTCGCGCTGGAGCTGGCGCGGGGCCCGGGCGGCGCCTACCGCGGCGGGGAGCGGCTGTGCGGC
CGGGTGCTGCTGGAGGCGGCGGCGCCGCTGCGGGTGCGAGCGCTCGAGGTGAAGGCGCGCGGCGGGGCGGCCACCCACTGGTTGGAGGGT
CGCAGCGTGGGCGTCAACGCCGTATCCAGCGACTACGCGGCCGCGGAGACCTACCTGCGGCGTCGGCAGCTGCTGCTCCGAGGTGCCATC
ATTGAAAATTGCGGGTCCAGCCCCGGGGAGGAGAGTGAGGTGGGTTCTATGGTGGGCGAAGGCTTCATCGAAGTCCTGACCAAGAAGCAG
CGCCGCCTGCTGGAGGAAGAGAGAAGAAAGAAGGAGCAGGCCGTGCAGGTGCCTGTCAAAGGTCGAGGCCTTTCCTCCCGTATTCCTCCT
CGATTTGCAAAAAAGCAGAACAACTTATGTCTGGAGCAAGGTGACGTGACCGTGCCTGGCAGCAGCCTGGGCACTGAGATCTGGGAGAGC
AGCAGCCAGGCTCTCCCTGTGCAGGCCCCAGCCAACGACTCCTGGAGGAAAGCTGTCACTGCCTTCAGCAGCACCGAGACTGGCTCTGCG
GAGCAGGGTTTTAAGAGCAGCCAGGGAGATAGTGGCGTTGACTTGAGTGCCGAGTCTCGGGAGTCGTCTGCGACCTCCTCGCAGCGCAGC
TCCCCATATGGGACTCTGAAGCCAGAGGAGATGAGCGGGCCCGGCCTGGCGGAACCCAAGGCCGACAGCCACAAGGAGCAGGCTCCAAAG
CCATCTGAGCAGAAGGATTCAGAACAAGGCTCTGGACAGAGCAAGGAGCACAGACCAGGACCCATCGGCAACGAGCGTTCTCTGAAAAAC
AGAAAGGGCTCGGAGGGGGCCGAGCGGCTGCAAGGGGCTGTCGTCCCGCCTGTTAACGGGGTGGAGATTCACGTGGACTCCGTGCTGCCT
GTGCCACCCATTGAATTTGGAGTCAGTCCAAAAGACTCCGATTTCAGCTTGCCACCTGGTTCTGCCTCTGGTCCTACTGGGAGTCCAGTT
GTTAAACTTCAGGATGCCTTGGCCAGTAATGCAGGGTTAACACAGAGTATCCCCATCCTGCGGCGGGACCATCACATCCAGAGGGCCATC
GGTCTCTCCCCAATGTCCTTCCCCACCGCCGACCTTACTCTGAAGATGGAGTCTGCGCGCAAGGCTTGGGAAAACTCCCCCAGTTTGCCG
GAGCAGAGCTCTCCAGGCGGCGCTGGCTCAGGCATCCAGCCTCCATCCTCTGTGGGTGCCTCCAGCGGGGTCAACTACAGCTCCTTCGGT
GGAGTGTCCATGCCACCCATGCCTGTGGCCTCTGTAGCACCTTCTGCTTCTATGCCAGGCAGCCACCTCCCGCCCCTGTACCTGGATGGC
CATGTGTTTGCAAGTCAGCCCCGGCTGGTTCCTCAAACGATACCTCAGCAGCAGAGTTACCAACAGGCCGCCGCTGCCCAGCAGATCCCG
ATCTCCCTTCACACATCTCTGCAGGCACAAGCTCAGCTTGGACTGAGGGGTGGGCTTCCTGTGTCCCAGTCCCAGGAGATCTTCAGCTCC
TTGCAGCCCTTCAGATCTCAGGTGTACATGCACCCCAGCCTGTCACCGCCCAGCACCATGATCCTCTCTGGGGGCACAGCCTTGAAGCCT
CCATACTCGGCGTTCCCAGGCATGCAGCCCTTGGAGATGGTGAAGCCGCAGTCTGGCTCACCCTACCAGCCCATGAGCGGGAACCAAGCC
CTGGTCTACGAGGGCCAGCTCAGCCAGGCTGCTGGCCTGGGTGCCTCCCAGATGTTGGACTCCCAGCTCCCACAGCTGACCATGCCACTG
CCTCGGTACGGCTCCGGGCAGCAGCCACTGATCCTGCCCCAGTCTATTCAGCTGCCACCTGGGCAGAGCCTCTCCGTTGGGGCCCCCCGA
AGGATTCCTCCGCCCGGGTCCCAGCCGCCAGTCCTGAACACCAGCAGAGAGCCCTCTCAGATGGAGATGAAAGGCTTCCACTTTGCCGAC
AGTAAACAGAATGTCCCTTCAGGAGGCCCCGTGCCATCGCCACAGACCTACAGGCCTAGCTCTGCTAGCCCCAGTGGGAAGCCCTCTGGA
TCAGCAGTTAACATGGGCTCTGTGCAGGGACACTACGTGCAACAGGCAAAACAACGAGTGGATGAGAAACCCAGCCTGGGAGCCGTGAAG
CTGCAGGAGGCCCCCTCGGCTGCCTCCCAGATGAAGCGAACCGGAGCGATCAAGCCTCGGGCTGTCAAAGTGGAGGAGAGTAAGGCCTGA
CAGTGCCTGGCTGCCACCTCGCCTCTCCCTACTGAGGACGGTGCCGCCATGCGGCCTCGACACAGCCGACACTCGGGAGCCTCACCAGAT
CCACCGTCCAAATGCGTGGCCCAGACTGAGAGACCTCCCTCCTCTCCACTCCCGAAAGCTCCGTTGTCAACCAGCTTGCACCCGTGGATA
TATGGCATTGACCCGCTTGCTTTGATACGAAACAAAAAAGCAGACGACTCCTTCATCCCATCTGCTCCTACCGTGACTGTGGAGTGACGC
CTCCTGTGCAGTGCAGATTTGCCCTCCCTGCCTCCTCCCTGTCCTGCCGCGCAGCCAGGGCGCCTTCTCAGCAGTGCTTCCGGCCCAGCC
GCCCATCCCTAGGCACAGTGATTTGGCAGCAGGGTCATTTTACTTTGAGGCTTTTTGTTTTAAAATGTAGCCAAGGTTTTTACAAAGGGG
AAAGGAAAAGAAAACAAAAACGCAAGCTCCATGTGTATAGCTGAACTTTTATATGTTTCTTGCCAGCCCCTCCGCTCCCTTCCATCTCTA
GCCTCTGTCCTGTTTAGTTTGATACGTCACTGCAGTACCTTAAGAGGTGACTCTTAAGAATGCATCCCCTCCTGATTCCTCAGCTGGTTC
ACCCTTGAGGTTATTTGCAAAAAGAAAAGGAGGTTCTTGAGGGCACCGATTGCGAGCATTCTGGTGCCTGGCTCCCCGCCTGGGAAGCGA
TGGGGTGCTCAGAGCAGCAGGCAGGTTGGGGGAGGGGGGGGGTCATAGTTGGGTTCCAGCTCCTGGCTTGATGAGCCCAGGGCGCTTACA
GGCAGCCCATGAAGTTGATGACAGTTTTAGCATGAGAATCACACAGGGTCCCTGTCCTGGGCTCCTCTAAAGCCAGTGGATGTGCTGGGC
ACCAGAGACAAATCATGGAGATGGCTGCTGGTGGCTCCCAGGTTGGCCCAGATGGGGTGAGCTGACATACCACAGGCCCATCCCAGGCCC
CGTGGGCTCTGCTTCTGGGGCTCCATACCCTGCCCTGCAGGGGTGCTGTGTTTTTCACACATTTCTTTCCCTGAAGCCTTCTGTAACCTG
TCATTTTCCTTCCTTCCTCTTCCGGAGCCTGCTGCTTTCTCTGGACCTGTCTCCACCTCCCACACAGCTCATCGTGAACACCACTTGGTG
ATGGAGGGAGTGGACCCGTGTGTGGTCCCCAAGTGAGGCCACTGGGAGTTTGTCCTTTTCCTCCTTTGCTTCACTCCCAGCAGCAGACCC
AGGTTGTCAGGACAGGAGGGCCTGAGCTAAGCAGTAGGCATCAGTCTCGTTTGTCTTCAGACGGCGGGGGCAGGTCCAGGGTGAGGCTGG
GTGGAGGGCTGACCAAGGTCCAAAGGGCCTGCGCAGCCTCCGGGAGGGCAGCTTCTCCAGCCAGAGGCTTGTGTGAGCCATCGTGTGCTG
GGCTTGTTTTTAAGTAAGAAACAAGGAAATCACTCCAGATTCTGTCATTCCAAGGAAAGGGAAGGGGACAGTTCAGGTTTCTCAGCTGTT
CTTAGGGGTCACTGAGCGTCTACCTCCTCCTCCAGAGGAGGCTGGCTCAGAACACCTAGAGGAGGGGGCCGGGGATGCACCCCCCACCAG
AGGCTGCCTTCAGCGTCTCACGGGTGCAGGACAGCGCTCAGGCTTGGGCTCTAAGCTCTGTGTCTAGTGTAGAACATGGGGAAGGAGCAT
CTTAGGAACTGCTGAAGTAACTTCTTACTGCTCTCACAATTCTAAGGAAGCGGGAGAACGGCCTCCTACCAACAGCGCCCACCCCAGAGC
TGCCTGGGAAAGGGCAGTTTTACTGAAAGGTGCTTTACTGTTCACCTGCATCTTTCAGCAGCTCCCCTCCTGCCCTCACCTGGTCTTTTC
CCTCTTTATCCCAAGCCTTTATGCTTGAGTCCCTTCCCCAGGGGCTGCCCACCCGACAGTTCCAGGCATTCCCTACCTGAGCTTCTTGTC
TGCTTTTCCTTCTCCCACTGCAAGCGGCTGCTTGTGGGGCCTGGGATGAGCCCTCTCTGTCCCCACCGGCCCTCCTTGCCAAGCCATTCC
TGGGTGAGTTCAGGCCTGCGGGAGCCACACATTCATCTCCACCTGGACACTTGAGCCGCATGGCCAGACCCCTCCCACCTGATGCGGTGG
TGCGTGTGATTTGTCAAAAGAAAGCCTTCTGGATGCTGTTAAGATGTACCCTTCAGGTGAACCTGGTATCAGACCCACAGTACTTGCTGT
TTGAGAAAAAATAAAAACAAAAAGGTCACCTGTTCTCCAGCCCTTTTCTCTTACCTGGTATTTCCTTCCTTTCTCCTCCCCCACCCCAAA
TAAAAAAACAAAAAACACTAGAATTTATTTATATGTATTGATGTTGTAGGTCTAGGTGAAAAAAAAAGAAGTAAATGTTTCACTGCTCTA
TTTATATATAATGTCTGAATTAATTCTGTGCAGGAAAGGCCAGGAAATTGCATGTGAAGTTCGGTGCAGTCACCACCTGTGTGTGACCTG
AGCTGCAGTCTCTTCGCTGAGATGCAGGTTTTAAATGAGACTTGGGGGGCTGAGGGCAGGCCTCAGGCCTCCCAGCGCCCCAACCCCTCC
TTGGTCTAATGAAATGCAGTTCTTAGTGCAGAGATGTTTTAAGGTGCAATATATCTCTTCCTTTCCCGTGGTTTTAGAGCCAAGCTCAAG
GTAGTAGGACGTAGGGTCTTATTTTGTTTTCAAACCCCCATCCTCAGAGCGCAGATACATGCAGAGGCTTCTGCCAGGATACCACGGGGC
CTTAGTGGGAACAGGTGGAGACCAGCACTTCCCTTTCCTGCTGCTGAGGTAGGGATTGGGGGGTCAGAACCCACTCACTTTTGCCTGTTA
AAGTTGCCCTCCTGACGCTGGCAGCTCTGCCTTGGTCACTGGGGATGCGGCTCGTTGCTCAGCCACCAGTGGCCTTGCGGTATTGTCCAC
CATCCACTAGAGTGGGATGAAGTCCAGAGTGTGGGTATACATCTCAGATGCCCATCTACCCACTGGGGACTTCAATGCCAGCTGCATTTG
GTTTGGTTTTCTTAACTGTTGGCTTCTCCCCACAGCGTTTTTTGTTTTTTTTTAAACATTCATATTGTTTTCAAACTTGGAATTCATAGA
CACTCTGGCTCTAGGTTCCTTAAGGGGGAAAACAAAAGATGACTTTATTTCACATTCAAGAAAATCAGTTCAGTTCCAAAGCTGTGGTCC
TTCCAGCCACTTCTAGGGACACTGGGGAACCTTGTTAAACGTTGACATCAGTGCTCTCCAGCCGTGCTGTCACCCTCCTATCTTCTGGAT
CTGCCTTCGCGATGGTCAGTGACAGCTTCTGGAAGCTGAGCACACACAGGTGCACAGCCATGCTGTGGTCTGGCCTGCTACGGCAGCATG
GCAGCTCTGGTGGAGCCTTCTCCCTTGCCATTTGGTTCCCCTGTGCCAAGTAGCTGCAGGCTGCCCCTCAAATCTTCATTTGTCCCTTTT
CACTTCCTGCAGAACAAGCCTGGGTTAGAGGGTCTGCTGGAAATGGCCTTTGAAGACCAAGGATACCAGGATGTGTGCACTCTGTCGTGT
TCTGTGATGAATGGGAAACGTAGGCTTCCAGAAAGCCAGCTCTCTTCTGAAATGTGACGGACCTAAGCAGGAAGTCATCCAGGACAGGAG
TGGCTCAGTGTTGGGGATGGACGCTGTCGCCCAGCCATGCTCCACCAGGGCCACCAATGTGTAGTTGGCTGGTGGTCTTCGGGCATGTGA
GACCTGCTCTTCACTGTTTCCACCCCACTTGGTGGCCTCCAGGATGGTAGTGGCACCCTCAGAGCCCCATCTTCAGCATGTTCTGAAGCC
TCAGAGTGGAAATTCCTGCTAAGGCTCTGTGTGGACGCCTTTCTCCCGTGATCTAAAGGGGACACTGTACTCAAGCTTTTGACCTCATGC
CTTGTGTAGTAAAAAAGGATTTGGGGGTTTTGTTTGGTTCCTGAGAGGGTTGTGTTTTGTTTTTGTTTCCTTTTGTTTATGTTTTGGCCT
TTCCTCTTTGTCTTTCCATGTAGACCAGATATTTGAAAGGGCAGACGATGGCTAGAGGTGTAATGTGCAGCTTGTTTATACGGTATTTTG
GGAAACTTACCTTGGATGGGAAATCGAATCGTGGATTCACCAGGCCGGTGCTGGCACACTCACCCTCGCCCTTTCCCTCCGGTTCAGTAC
CTATTGTTTCTCCTTTCAAATATGTGATTGTACTAGCTCTTTCCATATGAAAGAATTCTCCTTATTTAAATAAAAAAAGTTTAAAAAGAT

>6864_6864_2_ARRDC2-PRRC2B_ARRDC2_chr19_18112382_ENST00000379656_PRRC2B_chr9_134353861_ENST00000405995_length(amino acids)=813AA_BP=121
MGDATGERGNPGDLQARPGRVPSLRVSKPCPQPRAMRSGGVRSFALELARGPGGAYRGGERLCGRVLLEAAAPLRVRALEVKARGGAATH
WLEGRSVGVNAVSSDYAAAETYLRRRQLLLRGAIIENCGSSPGEESEVGSMVGEGFIEVLTKKQRRLLEEERRKKEQAVQVPVKGRGLSS
RIPPRFAKKQNNLCLEQGDVTVPGSSLGTEIWESSSQALPVQAPANDSWRKAVTAFSSTETGSAEQGFKSSQGDSGVDLSAESRESSATS
SQRSSPYGTLKPEEMSGPGLAEPKADSHKEQAPKPSEQKDSEQGSGQSKEHRPGPIGNERSLKNRKGSEGAERLQGAVVPPVNGVEIHVD
SVLPVPPIEFGVSPKDSDFSLPPGSASGPTGSPVVKLQDALASNAGLTQSIPILRRDHHIQRAIGLSPMSFPTADLTLKMESARKAWENS
PSLPEQSSPGGAGSGIQPPSSVGASSGVNYSSFGGVSMPPMPVASVAPSASMPGSHLPPLYLDGHVFASQPRLVPQTIPQQQSYQQAAAA
QQIPISLHTSLQAQAQLGLRGGLPVSQSQEIFSSLQPFRSQVYMHPSLSPPSTMILSGGTALKPPYSAFPGMQPLEMVKPQSGSPYQPMS
GNQALVYEGQLSQAAGLGASQMLDSQLPQLTMPLPRYGSGQQPLILPQSIQLPPGQSLSVGAPRRIPPPGSQPPVLNTSREPSQMEMKGF
HFADSKQNVPSGGPVPSPQTYRPSSASPSGKPSGSAVNMGSVQGHYVQQAKQRVDEKPSLGAVKLQEAPSAASQMKRTGAIKPRAVKVEE

--------------------------------------------------------------
>6864_6864_3_ARRDC2-PRRC2B_ARRDC2_chr19_18112382_ENST00000379656_PRRC2B_chr9_134353861_ENST00000458550_length(transcript)=2969nt_BP=442nt
CCAGGAAGTTCGCCGACGACGCGCCCGCCCTGGGCCACCGGCGCCGGCCCAAGTTCGCCGGGGGGGCCCGGAGGAAGCTTGGGGGACGCG
ACGGGGGAACGCGGAAACCCCGGGGATCTGCAGGCGCGCCCGGGCCGTGTGCCTTCTCTCCGCGTGTCCAAACCGTGTCCCCAGCCGCGC
GCCATGCGCTCTGGGGGCGTGCGCAGCTTCGCGCTGGAGCTGGCGCGGGGCCCGGGCGGCGCCTACCGCGGCGGGGAGCGGCTGTGCGGC
CGGGTGCTGCTGGAGGCGGCGGCGCCGCTGCGGGTGCGAGCGCTCGAGGTGAAGGCGCGCGGCGGGGCGGCCACCCACTGGTTGGAGGGT
CGCAGCGTGGGCGTCAACGCCGTATCCAGCGACTACGCGGCCGCGGAGACCTACCTGCGGCGTCGGCAGCTGCTGCTCCGAGGTGCCATC
ATTGAAAATTGCGGGTCCAGCCCCGGGGAGGAGAGTGAGGTGGGTTCTATGGTGGGCGAAGGCTTCATCGAAGTCCTGACCAAGAAGCAG
CGCCGCCTGCTGGAGGAAGAGAGAAGAAAGAAGGAGCAGGCCGTGCAGGTGCCTGTCAAAGGTCGAGGCCTTTCCTCCCGTATTCCTCCT
CGATTTGCAAAAAAGCAGAACAACTTATGTCTGGAGCAAGGTGACGTGACCGTGCCTGGCAGCAGCCTGGGCACTGAGATCTGGGAGAGC
AGCAGCCAGGCTCTCCCTGTGCAGGCCCCAGCCAACGACTCCTGGAGGAAAGCTGTCACTGCCTTCAGCAGCACCGAGACTGGCTCTGCG
GAGCAGGGTTTTAAGAGCAGCCAGGGAGATAGTGGCGTTGACTTGAGTGCCGAGTCTCGGGAGTCGTCTGCGACCTCCTCGCAGCGCAGC
TCCCCATATGGGACTCTGAAGCCAGAGGAGATGAGCGGGCCCGGCCTGGCGGAACCCAAGGCCGACAGCCACAAGGAGCAGGCTCCAAAG
CCATCTGAGCAGAAGGATTCAGAACAAGGCTCTGGACAGAGCAAGGAGCACAGACCAGGACCCATCGGCAACGAGCGTTCTCTGAAAAAC
AGAAAGGGCTCGGAGGGGGCCGAGCGGCTGCAAGGGGCTGTCGTCCCGCCTGTTAACGGGGTGGAGATTCACGTGGACTCCGTGCTGCCT
GTGCCACCCATTGAATTTGGAGTCAGTCCAAAAGACTCCGATTTCAGCTTGCCACCTGGTTCTGCCTCTGGTCCTACTGGGAGTCCAGTT
GTTAAACTTCAGGATGCCTTGGCCAGTAATGCAGGGTTAACACAGAGTATCCCCATCCTGCGGCGGGACCATCACATCCAGAGGGCCATC
GGTCTCTCCCCAATGTCCTTCCCCACCGCCGACCTTACTCTGAAGATGGAGTCTGCGCGCAAGGCTTGGGAAAACTCCCCCAGTTTGCCG
GAGCAGAGCTCTCCAGGCGGCGCTGGCTCAGGCATCCAGCCTCCATCCTCTGTGGGTGCCTCCAGCGGGGTCAACTACAGCTCCTTCGGT
GGAGTGTCCATGCCACCCATGCCTGTGGCCTCTGTAGCACCTTCTGCTTCTATGCCAGGCAGCCACCTCCCGCCCCTGTACCTGGATGGC
CATGTGTTTGCAAGTCAGCCCCGGCTGGTTCCTCAAACGATACCTCAGCAGCAGAGTTACCAACAGGCCGCCGCTGCCCAGCAGATCCCG
ATCTCCCTTCACACATCTCTGCAGGCACAAGCTCAGCTTGGACTGAGGGGTGGGCTTCCTGTGTCCCAGTCCCAGGAGATCTTCAGCTCC
TTGCAGCCCTTCAGATCTCAGGTGTACATGCACCCCAGCCTGTCACCGCCCAGCACCATGATCCTCTCTGGGGGCACAGCCTTGAAGCCT
CCATACTCGGCGTTCCCAGGCATGCAGCCCTTGGAGATGGTGAAGCCGCAGTCTGGCTCACCCTACCAGCCCATGAGCGGGAACCAAGCC
CTGGTCTACGAGGGCCAGCTCAGCCAGGCTGCTGGCCTGGGTGCCTCCCAGATGTTGGACTCCCAGCTCCCACAGCTGACCATGCCACTG
CCTCGGTACGGCTCCGGGCAGCAGCCACTGATCCTGCCCCAGTCTATTCAGCTGCCACCTGGGCAGAGCCTCTCCGTTGGGGCCCCCCGA
AGGATTCCTCCGCCCGGGTCCCAGCCGCCAGTCCTGAACACCAGCAGAGAGCCCTCTCAGATGGAGATGAAAGGCTTCCACTTTGCCGAC
AGTAAACAGAATGTCCCTTCAGGAGGCCCCGTGCCATCGCCACAGACCTACAGGCCTAGCTCTGCTAGCCCCAGTGGGAAGCCCTCTGGA
TCAGCAGTTAACATGGGCTCTGTGCAGGGACACTACGTGCAACAGGCAAAACAACGAGTGGATGAGAAACCCAGCCTGGGAGCCGTGAAG
CTGCAGGAGGCCCCCTCGGCTGCCTCCCAGATGAAGCGAACCGGAGCGATCAAGCCTCGGGCTGTCAAAGTGGAGGAGAGTAAGGCCTGA
CAGTGCCTGGCTGCCACCTCGCCTCTCCCTACTGAGGACGGTGCCGCCATGCGGCCTCGACACAGCCGACACTCGGGAGCCTCACCAGAT
CCACCGTCCAAATGCGTGGCCCAGACTGAGAGACCTCCCTCCTCTCCACTCCCGAAAGCTCCGTTGTCAACCAGCTTGCACCCGTGGATA
TATGGCATTGACCCGCTTGCTTTGATACGAAACAAAAAAGCAGACGACTCCTTCATCCCATCTGCTCCTACCGTGACTGTGGAGTGACGC
CTCCTGTGCAGTGCAGATTTGCCCTCCCTGCCTCCTCCCTGTCCTGCCGCGCAGCCAGGGCGCCTTCTCAGCAGTGCTTCCGGCCCAGCC

>6864_6864_3_ARRDC2-PRRC2B_ARRDC2_chr19_18112382_ENST00000379656_PRRC2B_chr9_134353861_ENST00000458550_length(amino acids)=813AA_BP=121
MGDATGERGNPGDLQARPGRVPSLRVSKPCPQPRAMRSGGVRSFALELARGPGGAYRGGERLCGRVLLEAAAPLRVRALEVKARGGAATH
WLEGRSVGVNAVSSDYAAAETYLRRRQLLLRGAIIENCGSSPGEESEVGSMVGEGFIEVLTKKQRRLLEEERRKKEQAVQVPVKGRGLSS
RIPPRFAKKQNNLCLEQGDVTVPGSSLGTEIWESSSQALPVQAPANDSWRKAVTAFSSTETGSAEQGFKSSQGDSGVDLSAESRESSATS
SQRSSPYGTLKPEEMSGPGLAEPKADSHKEQAPKPSEQKDSEQGSGQSKEHRPGPIGNERSLKNRKGSEGAERLQGAVVPPVNGVEIHVD
SVLPVPPIEFGVSPKDSDFSLPPGSASGPTGSPVVKLQDALASNAGLTQSIPILRRDHHIQRAIGLSPMSFPTADLTLKMESARKAWENS
PSLPEQSSPGGAGSGIQPPSSVGASSGVNYSSFGGVSMPPMPVASVAPSASMPGSHLPPLYLDGHVFASQPRLVPQTIPQQQSYQQAAAA
QQIPISLHTSLQAQAQLGLRGGLPVSQSQEIFSSLQPFRSQVYMHPSLSPPSTMILSGGTALKPPYSAFPGMQPLEMVKPQSGSPYQPMS
GNQALVYEGQLSQAAGLGASQMLDSQLPQLTMPLPRYGSGQQPLILPQSIQLPPGQSLSVGAPRRIPPPGSQPPVLNTSREPSQMEMKGF
HFADSKQNVPSGGPVPSPQTYRPSSASPSGKPSGSAVNMGSVQGHYVQQAKQRVDEKPSLGAVKLQEAPSAASQMKRTGAIKPRAVKVEE

--------------------------------------------------------------

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Fusion Gene PPI Analysis for ARRDC2-PRRC2B


check button Go to ChiPPI (Chimeric Protein-Protein interactions) to see the chimeric PPI interaction in

ChiPPI page.


check button Protein-protein interactors with each fusion partner protein in wild-type (BIOGRID-3.4.160)
HgeneHgene's interactorsTgeneTgene's interactors


check button - Retained PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenStill interaction with


check button - Lost PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


check button - Retained PPIs, but lost function due to frame-shift fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


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Related Drugs for ARRDC2-PRRC2B


check button Drugs targeting genes involved in this fusion gene.
(DrugBank Version 5.1.8 2021-05-08)
PartnerGeneUniProtAccDrugBank IDDrug nameDrug activityDrug typeDrug status

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Related Diseases for ARRDC2-PRRC2B


check button Diseases associated with fusion partners.
(DisGeNet 4.0)
PartnerGeneDisease IDDisease name# pubmedsSource