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Center for Computational Systems Medicine
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Fusion Gene Summary

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Fusion Gene ORF analysis

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Fusion Genomic Features

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Fusion Protein Features

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Fusion Gene Sequence

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Fusion Gene PPI analysis

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Related Drugs

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Related Diseases

Fusion gene:PRKAR1A-NDFIP2 (FusionGDB2 ID:68659)

Fusion Gene Summary for PRKAR1A-NDFIP2

check button Fusion gene summary
Fusion gene informationFusion gene name: PRKAR1A-NDFIP2
Fusion gene ID: 68659
HgeneTgene
Gene symbol

PRKAR1A

NDFIP2

Gene ID

5573

54602

Gene nameprotein kinase cAMP-dependent type I regulatory subunit alphaNedd4 family interacting protein 2
SynonymsACRDYS1|ADOHR|CAR|CNC|CNC1|PKR1|PPNAD1|PRKAR1|TSE1N4WBP5A
Cytomap

17q24.2

13q31.1

Type of geneprotein-codingprotein-coding
DescriptioncAMP-dependent protein kinase type I-alpha regulatory subunitCarney complex type 1cAMP-dependent protein kinase regulatory subunit RIalphacAMP-dependent protein kinase type I-alpha regulatory chainepididymis secretory sperm binding proteinprotein kinNEDD4 family-interacting protein 2MAPK-activating protein PM04 PM05 PM06 PM07NEDD4 WW domain-binding protein 5ANF-kappa-B-activating protein 413putative MAPK-activating protein PM04/PM05/PM06/PM07putative NF-kappa-B-activating protein 413
Modification date2020032920200313
UniProtAcc.

Q9NV92

Ensembl transtripts involved in fusion geneENST00000358598, ENST00000392711, 
ENST00000536854, ENST00000586397, 
ENST00000588188, ENST00000589228, 
ENST00000494647, ENST00000218652, 
Fusion gene scores* DoF score15 X 15 X 8=18004 X 2 X 4=32
# samples 184
** MAII scorelog2(18/1800*10)=-3.32192809488736
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0		log2(4/32*10)=0.321928094887362
effective Gene in Pan-Cancer Fusion Genes (eGinPCFGs).
DoF>8 and MAII>0
Context

PubMed: PRKAR1A [Title/Abstract] AND NDFIP2 [Title/Abstract] AND fusion [Title/Abstract]

Most frequent breakpointPRKAR1A(66511717)-NDFIP2(80094945), # samples:1
Anticipated loss of major functional domain due to fusion event.
* DoF score (Degree of Frequency) = # partners X # break points X # cancer types
** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10)

check button Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez
PartnerGeneGO IDGO termPubMed ID
HgenePRKAR1A

GO:2000480

negative regulation of cAMP-dependent protein kinase activity

21812984


check buttonFusion gene breakpoints across PRKAR1A (5'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.
all structure

check buttonFusion gene breakpoints across NDFIP2 (3'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.
all structure

check button Fusion gene information from two resources (ChiTars 5.0 and ChimerDB 4.0)
* All genome coordinats were lifted-over on hg19.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
SourceDiseaseSampleHgeneHchrHbpHstrandTgeneTchrTbpTstrand
ChimerDB4STADTCGA-D7-A4Z0-01APRKAR1Achr17

66511717

+NDFIP2chr13

80094945

+


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Fusion Gene ORF analysis for PRKAR1A-NDFIP2

check button Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
ORFHenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrand
5CDS-3UTRENST00000358598ENST00000494647PRKAR1Achr17

66511717

+NDFIP2chr13

80094945

+
5CDS-3UTRENST00000392711ENST00000494647PRKAR1Achr17

66511717

+NDFIP2chr13

80094945

+
5CDS-3UTRENST00000536854ENST00000494647PRKAR1Achr17

66511717

+NDFIP2chr13

80094945

+
5CDS-3UTRENST00000586397ENST00000494647PRKAR1Achr17

66511717

+NDFIP2chr13

80094945

+
5CDS-3UTRENST00000588188ENST00000494647PRKAR1Achr17

66511717

+NDFIP2chr13

80094945

+
5CDS-3UTRENST00000589228ENST00000494647PRKAR1Achr17

66511717

+NDFIP2chr13

80094945

+
In-frameENST00000358598ENST00000218652PRKAR1Achr17

66511717

+NDFIP2chr13

80094945

+
In-frameENST00000392711ENST00000218652PRKAR1Achr17

66511717

+NDFIP2chr13

80094945

+
In-frameENST00000536854ENST00000218652PRKAR1Achr17

66511717

+NDFIP2chr13

80094945

+
In-frameENST00000586397ENST00000218652PRKAR1Achr17

66511717

+NDFIP2chr13

80094945

+
In-frameENST00000588188ENST00000218652PRKAR1Achr17

66511717

+NDFIP2chr13

80094945

+
In-frameENST00000589228ENST00000218652PRKAR1Achr17

66511717

+NDFIP2chr13

80094945

+

check buttonORFfinder result based on the fusion transcript sequence of in-frame fusion genes.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandSeq length
(transcript)		BP loci
(transcript)		Predicted start
(transcript)		Predicted stop
(transcript)		Seq length
(amino acids)
ENST00000358598PRKAR1Achr1766511717+ENST00000218652NDFIP2chr1380094945+4546294117983288
ENST00000392711PRKAR1Achr1766511717+ENST00000218652NDFIP2chr1380094945+46133611841050288
ENST00000589228PRKAR1Achr1766511717+ENST00000218652NDFIP2chr1380094945+455730556994312
ENST00000536854PRKAR1Achr1766511717+ENST00000218652NDFIP2chr1380094945+46674152051104299
ENST00000586397PRKAR1Achr1766511717+ENST00000218652NDFIP2chr1380094945+50087565281445305
ENST00000588188PRKAR1Achr1766511717+ENST00000218652NDFIP2chr1380094945+44291770866288

check buttonDeepORF prediction of the coding potential based on the fusion transcript sequence of in-frame fusion genes. DeepORF is a coding potential classifier based on convolutional neural network by comparing the real Ribo-seq data. If the no-coding score < 0.5 and coding score > 0.5, then the in-frame fusion transcript is predicted as being likely translated.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandNo-coding scoreCoding score
ENST00000358598ENST00000218652PRKAR1Achr1766511717+NDFIP2chr1380094945+0.0001303780.9998696
ENST00000392711ENST00000218652PRKAR1Achr1766511717+NDFIP2chr1380094945+0.0001333870.9998666
ENST00000589228ENST00000218652PRKAR1Achr1766511717+NDFIP2chr1380094945+0.0001298210.9998702
ENST00000536854ENST00000218652PRKAR1Achr1766511717+NDFIP2chr1380094945+0.0001324370.99986756
ENST00000586397ENST00000218652PRKAR1Achr1766511717+NDFIP2chr1380094945+0.0001211680.99987876
ENST00000588188ENST00000218652PRKAR1Achr1766511717+NDFIP2chr1380094945+0.0001225160.99987745

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Fusion Genomic Features for PRKAR1A-NDFIP2


check buttonFusionAI prediction of the potential fusion gene breakpoint based on the pre-mature RNA sequence context (+/- 5kb of individual partner genes, total 20kb length sequence). FusionAI is a fusion gene breakpoint classifier based on convolutional neural network by comparing the fusion positive and negative sequence context of ~ 20K fusion gene data. From here, we can have the relative potentency of the 20K genomic sequence how individual sequnce will be likely used as the gene fusion breakpoints.
HgeneHchrHbpHstrandTgeneTchrTbpTstrand1-pp (fusion gene breakpoint)
PRKAR1Achr1766511717+NDFIP2chr1380094944+1.93E-091
PRKAR1Achr1766511717+NDFIP2chr1380094944+1.93E-091

check buttonDistribution of 44 human genomic features loci across 20kb length fusion breakpoint regions. We integrated a total of 44 different types of human genomic feature loci information across five big categories including virus integration sites, repeats, structural variants, chromatin states, and gene expression regulation. More details are in help page.
genomic feature

check buttonDistribution of 44 human genomic features loci across 20kb length fusion breakpoint regions that are ovelapped with the top 1% feature importance score regions. More details are in help page.
genomic feature of top 1%

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Fusion Protein Features for PRKAR1A-NDFIP2


check button Four levels of functional features of fusion genes
Go to FGviewer search page for the most frequent breakpoint (https://ccsmweb.uth.edu/FGviewer/chr17:66511717/chr13:80094945)
- FGviewer provides the online visualization of the retention search of the protein functional features across DNA, RNA, protein, and pathological levels.
- How to search
1. Put your fusion gene symbol.
2. Press the tab key until there will be shown the breakpoint information filled.
4. Go down and press 'Search' tab twice.
4. Go down to have the hyperlink of the search result.
5. Click the hyperlink.
6. See the FGviewer result for your fusion gene.
FGviewer

check buttonMain function of each fusion partner protein. (from UniProt)
HgeneTgene
.NDFIP2

Q9NV92

FUNCTION: Transcriptional activator which is required for calcium-dependent dendritic growth and branching in cortical neurons. Recruits CREB-binding protein (CREBBP) to nuclear bodies. Component of the CREST-BRG1 complex, a multiprotein complex that regulates promoter activation by orchestrating a calcium-dependent release of a repressor complex and a recruitment of an activator complex. In resting neurons, transcription of the c-FOS promoter is inhibited by BRG1-dependent recruitment of a phospho-RB1-HDAC1 repressor complex. Upon calcium influx, RB1 is dephosphorylated by calcineurin, which leads to release of the repressor complex. At the same time, there is increased recruitment of CREBBP to the promoter by a CREST-dependent mechanism, which leads to transcriptional activation. The CREST-BRG1 complex also binds to the NR2B promoter, and activity-dependent induction of NR2B expression involves a release of HDAC1 and recruitment of CREBBP (By similarity). {ECO:0000250}.FUNCTION: Activates HECT domain-containing E3 ubiquitin-protein ligases, including ITCH, NEDD4, NEDD4L, SMURF2, WWP1 and WWP2, and consequently modulates the stability of their targets. As a result, may control many cellular processes. Recruits ITCH, NEDD4 and SMURF2 to endosomal membranes. Negatively regulates KCNH2 potassium channel activity by decreasing its cell-surface expression and interfering with channel maturation through recruitment of NEDD4L to the Golgi apparatus and multivesicular body where it mediates KCNH2 degradation (PubMed:26363003). May modulate EGFR signaling. Together with NDFIP1, limits the cytokine signaling and expansion of effector Th2 T-cells by promoting degradation of JAK1, probably by ITCH- and NEDD4L-mediated ubiquitination (By similarity). {ECO:0000250|UniProtKB:Q91ZP6, ECO:0000269|PubMed:12761501, ECO:0000269|PubMed:19343052, ECO:0000269|PubMed:20534535, ECO:0000269|PubMed:26363003}.

check buttonRetention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at

download page


* Minus value of BPloci means that the break pointn is located before the CDS.
- In-frame and retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
TgeneNDFIP2chr17:66511717chr13:80094945ENST0000021865208148_1511071399.3333333333333MotifNote=PPxY motif 1
TgeneNDFIP2chr17:66511717chr13:80094945ENST0000021865208174_1771071399.3333333333333MotifNote=PPxY motif 2
TgeneNDFIP2chr17:66511717chr13:80094945ENST0000021865208184_1861071399.3333333333333MotifNote=PPxY motif 3
TgeneNDFIP2chr17:66511717chr13:80094945ENST0000021865208253_2571071399.3333333333333Topological domainExtracellular
TgeneNDFIP2chr17:66511717chr13:80094945ENST0000021865208279_2871071399.3333333333333Topological domainCytoplasmic
TgeneNDFIP2chr17:66511717chr13:80094945ENST0000021865208309_3361071399.3333333333333Topological domainExtracellular
TgeneNDFIP2chr17:66511717chr13:80094945ENST0000021865208232_2521071399.3333333333333TransmembraneHelical
TgeneNDFIP2chr17:66511717chr13:80094945ENST0000021865208258_2781071399.3333333333333TransmembraneHelical
TgeneNDFIP2chr17:66511717chr13:80094945ENST0000021865208288_3081071399.3333333333333TransmembraneHelical

- In-frame and not-retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
HgenePRKAR1Achr17:66511717chr13:80094945ENST00000358598+21196_10059382.0MotifNote=Pseudophosphorylation motif
HgenePRKAR1Achr17:66511717chr13:80094945ENST00000392711+21196_10059382.0MotifNote=Pseudophosphorylation motif
HgenePRKAR1Achr17:66511717chr13:80094945ENST00000536854+31296_10059382.0MotifNote=Pseudophosphorylation motif
HgenePRKAR1Achr17:66511717chr13:80094945ENST00000586397+11096_10059382.0MotifNote=Pseudophosphorylation motif
HgenePRKAR1Achr17:66511717chr13:80094945ENST00000589228+21196_10059382.0MotifNote=Pseudophosphorylation motif
HgenePRKAR1Achr17:66511717chr13:80094945ENST00000358598+211137_25459382.0Nucleotide bindingNote=cAMP 1
HgenePRKAR1Achr17:66511717chr13:80094945ENST00000358598+211255_38159382.0Nucleotide bindingNote=cAMP 2
HgenePRKAR1Achr17:66511717chr13:80094945ENST00000392711+211137_25459382.0Nucleotide bindingNote=cAMP 1
HgenePRKAR1Achr17:66511717chr13:80094945ENST00000392711+211255_38159382.0Nucleotide bindingNote=cAMP 2
HgenePRKAR1Achr17:66511717chr13:80094945ENST00000536854+312137_25459382.0Nucleotide bindingNote=cAMP 1
HgenePRKAR1Achr17:66511717chr13:80094945ENST00000536854+312255_38159382.0Nucleotide bindingNote=cAMP 2
HgenePRKAR1Achr17:66511717chr13:80094945ENST00000586397+110137_25459382.0Nucleotide bindingNote=cAMP 1
HgenePRKAR1Achr17:66511717chr13:80094945ENST00000586397+110255_38159382.0Nucleotide bindingNote=cAMP 2
HgenePRKAR1Achr17:66511717chr13:80094945ENST00000589228+211137_25459382.0Nucleotide bindingNote=cAMP 1
HgenePRKAR1Achr17:66511717chr13:80094945ENST00000589228+211255_38159382.0Nucleotide bindingNote=cAMP 2
HgenePRKAR1Achr17:66511717chr13:80094945ENST00000358598+2111_13659382.0RegionNote=Dimerization and phosphorylation
HgenePRKAR1Achr17:66511717chr13:80094945ENST00000392711+2111_13659382.0RegionNote=Dimerization and phosphorylation
HgenePRKAR1Achr17:66511717chr13:80094945ENST00000536854+3121_13659382.0RegionNote=Dimerization and phosphorylation
HgenePRKAR1Achr17:66511717chr13:80094945ENST00000586397+1101_13659382.0RegionNote=Dimerization and phosphorylation
HgenePRKAR1Achr17:66511717chr13:80094945ENST00000589228+2111_13659382.0RegionNote=Dimerization and phosphorylation
TgeneNDFIP2chr17:66511717chr13:80094945ENST00000218652081_2311071399.3333333333333Topological domainCytoplasmic


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Fusion Gene Sequence for PRKAR1A-NDFIP2


check button For in-frame fusion transcripts, we provide the fusion transcript sequences and fusion amino acid sequences. To have fusion amino acid sequence, we ran ORFfinder and chose the longest ORF among the all predicted ones.
>68659_68659_1_PRKAR1A-NDFIP2_PRKAR1A_chr17_66511717_ENST00000358598_NDFIP2_chr13_80094945_ENST00000218652_length(transcript)=4546nt_BP=294nt
GGTGGACAGAGGAGCGGAGGGACGAGAGGGAAGCGCACGATAGCTGCGCGGAGAGAGAGCGAAGAGCAGGCGGAGGAACAAAGGCGACCC
AAGACACCCAGAGAGGGACAGAGAACCATGGAGTCTGGCAGTACCGCCGCCAGTGAGGAGGCACGCAGCCTTCGAGAATGTGAGCTCTAC
GTCCAGAAGCATAACATTCAAGCGCTGCTCAAAGATTCTATTGTGCAGTTGTGCACTGCTCGACCTGAGAGACCCATGGCATTCCTCAGG
GAATACTTTGAGAGGTTGGAGAAGCTTCTTAATGAAGAGGATAACTCAGAATCATCGGCTATAGAGCAGCCACCTACTTCAAACCCAGCA
CCGCAGATTGTGCAGGCTGCGTCTTCAGCACCAGCACTTGAAACTGACTCTTCCCCTCCACCATATAGTAGTATTACTGTGGAAGTACCT
ACAACTTCAGATACAGAAGTTTACGGTGAGTTTTATCCCGTGCCACCTCCCTATAGCGTTGCTACCTCTCTTCCTACATACGATGAAGCT
GAGAAGGCTAAAGCTGCTGCAATGGCAGCTGCAGCAGCAGAAACATCTCAAAGAATTCAGGAGGAAGAGTGTCCACCAAGAGATGACTTC
AGTGATGCAGACCAGCTCAGAGTGGGGAATGATGGCATTTTCATGCTGGCATTTTTCATGGCATTTATTTTCAACTGGCTTGGATTTTGT
TTATCCTTCTGTATCACCAATACCATAGCTGGAAGGTATGGTGCTATCTGCGGATTTGGCCTTTCCTTGATCAAATGGATCCTTATTGTC
AGGTTTTCTGATTATTTTACTGGATATTTCAATGGACAGTATTGGCTTTGGTGGATATTTCTTGTACTTGGCCTGCTCCTTTTCTTCAGA
GGATTTGTTAATTATCTAAAAGTCAGAAACATGTCTGAAAGTATGGCAGCTGCTCATAGAACAAGGTATTTCTTCTTATTGTAGAGACTG
CATCAACCCGACATTCCTTTCTTATACCAATGTGAAATTTCCAGATCATCTGTAAACCTACAACTTTAATAGAAGACTACTAATAACAGA
AGACAAATTAGTGAAGAAAAGACGGAGTTTCGAAATTGAATGGCAGGGTGGTTTTTGCTTACAAGCCATTTCTGTTCATTCTTTAAGTAT
CTATATTTCATTTGTTTTGCACATATGCATATGTGCCCATTTAAGATATTTGCATATACTTGATAGAAACCATAAAGTTGTAGCAGTTAA
GTCCAGTCACATTTGGTTAATCAGTGTTTGATATAATTGAAAGAGTTGAGTGGATAAACAGTCTTCCAGCTTGTAAATGCCATTGACTTC
TGACCTGACATTTAGTATAATAAAAATGAAATTCTTAACCATGTCAAATGATTTAGTTTCTGGCTCTTAGACTCATCTGGCAGTTCTACA
CATGAAACATCTTTTGTTATATAAGGTGTATTGAAACCTGCAGTGCTGATTATTAGAAAGGATTTGTCAGATTTTTGAACATGATATTTA
CATTATTATTTAGGAAAACTCTTCCTGTAAATAACCATGCATAACTTACTTTCTGCAATGTTTTCTTAGAAATTGTGTCCAGATAGCTTT
CACTAATTTTAAATTAAGTGAACTAAATATATATGTGTATATGTATACACATATATATACACACACACATATATATATTTAGAAACGTGA
GTGTTAAAGATAGAATTTGTTTTAGGACAAATTTTAAGAAAATGTGGGAATACCAAATGTCCTTTATAAGAAAAATAAATTTTATTTTAA
GGGACATACTAGTTTTAGGGATTTTCAGATGGGAAGCTGCATTTTTAGGATTGCCCATCTTAAGAGATCTTGCAGGAAGAGATTGTATTA
GATATTATATTTATTTCATTTAAGATAATTTTCAAAGTTAATTTTCTAAATAAGATAATTCTCATTTGTGTTTGTCTTTTAAAAGGCCAA
TAAAATATCTTTCAGTATCATTGTAATAATTTTTTAGAGTTTAATTTGTAAAGCTTAGCAAATAAAATCTTGTACTATGAATAGCTTCTT
GCTTTATGACTTTAGGATTAACTTGTAAAAAACATATCCTGAACTGAGATATGCAAAATACTCATTTTCAAGTTATGGAAATGTGTTTGT
GGCATATAGGACTGTGGGGTCTGTGTGTGTAGTGAGAGTGTGTAGCCACTATTATAACTGGAATTTAATTTACATTCATAAACTACTATA
TTTCCCATCTTGCAAATCATTTTATGTCTCATCTGTTTTTCCTTTCGGTTATATCTTTGGTTTTGAATACCAACATTTAAAATGATGGTA
TTTTATCTTTTAAACTTAAAAATTATTTAATACAGCTATATGGACCTTATAAAATTGATTTCTTATTTATTATTAGACATTACTACTAAA
AGGTACATCTAACTATTCAGGGACATTTTTCCATTTCCAAAAAATAAAATTTATTATGCTTTATAACCTCTTCTGTATTTTCTAATTTTT
TCATTGTCTTTGATAAATAAAACAGTTTTGTTTTGCTAATATAGCCTATTTTTTGTTTTGTCTCATTCAGTTTACTTTCCTGCGTAGAAT
TTTTATTGTTATATTAAAATTTTTATTGTTGTATTAAAGTACCTGTGTTACACCCCTTGAAGTAAGACAGTAGCATGGGGTAAAGAAAAA
ATATTTAGTTTAGTTGCCTAATTTGGAAGTTAATTAAAATTAAACTGTACTAATAACATATTCAAACTCATGCTGGATCTCTTTCATATT
AATTTCTTATAGACCTGTACTTTATTCTTTCAATAATTTTTAAATGAAATTAAGCTTTGCTACATGGTAATTAAATAATTACTAGGAAGC
TTAGCTATCAAACATCGACTTACTAAAATTTCATTTTAGCTTTTATGGTATATGTGCTTGTTTTCTGAATATGGATACATGTTACTTTTG
ATCCAGCATCAAAACTTCACTTTTTGTTTTGACTTTTCCCCCCAAATCTGTAAGGTTCAAGTATACATATTACTGAATCCTCTATAATTG
GCATAATTCAATGGTAGCCTTAAATCTCATCATGTAAGCAGGGGAATCAGAATGTTATTTTCAAGAACTTAATGTTCCCTTCAGATATAT
AAAATCCTGCATACTTCATTTCCTGTGAGCTTGAACAGCTGCTGTTGTGTTTTGGGGATGCTTGATCATCTTTGCACTCTGCCTTAAAGA
TTGAAAAATCAAAACTCTTGTTAGGGTATCTAAACATTTTTGAGTGTGAACTGGGGATTGGAAGTTAATACAAAAAAATTTCAAATTATT
TCTATTGTAAATGAATAAGCTAGTCATGGCTAGGATAATCCATTTTCATGTATTTATGCAATAAACTGAATTTTAAGGCAAAAACAACAC
TTTTCTATATAGTGTATGCAGGACAGATTTTAGAAACTTAGATTAAAATACAAATCCCATTACATTTGGTTAAAATGAAAATCTCTGCTT
AATGGAAAAAATACTAATCTTTAGCCTATTTTGAGTCTATAAGATATATTTCATTTTAGACATGCCTTCTAAGTTGTTCACAGATTTTTA
CCTGCTAAAACAATATTATTTCCAGTAAAACCTCTCCTAACAGGAAAAGTGGAGTTCAAAATATCCAATTGGAGAAAAATTCAGAGTTCC
TTCATTAAATATAATTTTTTTCATCTAGTATGTACTATTTCAAGAAGTGCAAAAAGTAATGATAGTGAATGTGATACCATACTTAACTAA
GGTAATATATATCCTTAGTTTGCTCAAAAGAGTCCTGGTTATTCCTGTTTTCTCAGCTTAATAGTGCCTCATCGTACTCTCAAAAGTGTT
CTAATTTGGAGGATAAGTTATATGATCATCCTGTGTATAATTGTAGACTGTACCAAGAAGCAACTACCTTAGCTCCACTGCCCTTTGAGG
GATGGAACTGGGGTAAGGGCAGGAGCCAGTTATTATTGCCACAGTGTTTTCTAATGAACCATTTGGCCTGTAGAAGAGGAATAGTATTTT
TTTTAATAGTTGTATTTGAATGATTCCAGCTTATCGTAAATACTAAACTGAATGGCTTTTATATTTTTAACTGCTGTTAAATGTTATTTT
AGCATTTATTAGTTGTTTATTATTTAATTCTTCAAATAGTCATATGAAAACATATATTTGATAAAGGTCAATTGTTAGATGATAATGTGC
CATTCATTATCATAGGAATGTCCTTGCCCATATATAAAACATGCTGGCATGTATTTTACTTGTTAATAAAGTTGTATAGATGTGGAAGTG
TGAACCTGTGATGCATCCTTTTCAAAATCAGTTTAAGATTCGCATATTATCATGACTGTGACCTCACTAAACTGTTTATGTGACAAACCT
TTCAAGATTGGAGATGAAAACAACACTTGTGAAATTAGGTTGGGGTTGCAACATCTTTTAACTTCTCAGTTATTTGTATGTCAGGAGACA

>68659_68659_1_PRKAR1A-NDFIP2_PRKAR1A_chr17_66511717_ENST00000358598_NDFIP2_chr13_80094945_ENST00000218652_length(amino acids)=288AA_BP=48
MESGSTAASEEARSLRECELYVQKHNIQALLKDSIVQLCTARPERPMAFLREYFERLEKLLNEEDNSESSAIEQPPTSNPAPQIVQAASS
APALETDSSPPPYSSITVEVPTTSDTEVYGEFYPVPPPYSVATSLPTYDEAEKAKAAAMAAAAAETSQRIQEEECPPRDDFSDADQLRVG
NDGIFMLAFFMAFIFNWLGFCLSFCITNTIAGRYGAICGFGLSLIKWILIVRFSDYFTGYFNGQYWLWWIFLVLGLLLFFRGFVNYLKVR

--------------------------------------------------------------
>68659_68659_2_PRKAR1A-NDFIP2_PRKAR1A_chr17_66511717_ENST00000392711_NDFIP2_chr13_80094945_ENST00000218652_length(transcript)=4613nt_BP=361nt
GATTGGCTGCGGCCAGGCCGTTTCCGGTGGAGCTGTCGCCTAGCCGCTATCGCAGAGTGGAGCGGGGCTGGGAGCAAAGCGCTGAGGGAG
CTCGGTACGCCGCCGCCTCGCACCCGCAGCCTCGCGCCCGCCGCCGCCCGTCCCCAGGTGAGTGGGGTCGGCCGGGGGCTCAGGCGAGAG
AACCATGGAGTCTGGCAGTACCGCCGCCAGTGAGGAGGCACGCAGCCTTCGAGAATGTGAGCTCTACGTCCAGAAGCATAACATTCAAGC
GCTGCTCAAAGATTCTATTGTGCAGTTGTGCACTGCTCGACCTGAGAGACCCATGGCATTCCTCAGGGAATACTTTGAGAGGTTGGAGAA
GCTTCTTAATGAAGAGGATAACTCAGAATCATCGGCTATAGAGCAGCCACCTACTTCAAACCCAGCACCGCAGATTGTGCAGGCTGCGTC
TTCAGCACCAGCACTTGAAACTGACTCTTCCCCTCCACCATATAGTAGTATTACTGTGGAAGTACCTACAACTTCAGATACAGAAGTTTA
CGGTGAGTTTTATCCCGTGCCACCTCCCTATAGCGTTGCTACCTCTCTTCCTACATACGATGAAGCTGAGAAGGCTAAAGCTGCTGCAAT
GGCAGCTGCAGCAGCAGAAACATCTCAAAGAATTCAGGAGGAAGAGTGTCCACCAAGAGATGACTTCAGTGATGCAGACCAGCTCAGAGT
GGGGAATGATGGCATTTTCATGCTGGCATTTTTCATGGCATTTATTTTCAACTGGCTTGGATTTTGTTTATCCTTCTGTATCACCAATAC
CATAGCTGGAAGGTATGGTGCTATCTGCGGATTTGGCCTTTCCTTGATCAAATGGATCCTTATTGTCAGGTTTTCTGATTATTTTACTGG
ATATTTCAATGGACAGTATTGGCTTTGGTGGATATTTCTTGTACTTGGCCTGCTCCTTTTCTTCAGAGGATTTGTTAATTATCTAAAAGT
CAGAAACATGTCTGAAAGTATGGCAGCTGCTCATAGAACAAGGTATTTCTTCTTATTGTAGAGACTGCATCAACCCGACATTCCTTTCTT
ATACCAATGTGAAATTTCCAGATCATCTGTAAACCTACAACTTTAATAGAAGACTACTAATAACAGAAGACAAATTAGTGAAGAAAAGAC
GGAGTTTCGAAATTGAATGGCAGGGTGGTTTTTGCTTACAAGCCATTTCTGTTCATTCTTTAAGTATCTATATTTCATTTGTTTTGCACA
TATGCATATGTGCCCATTTAAGATATTTGCATATACTTGATAGAAACCATAAAGTTGTAGCAGTTAAGTCCAGTCACATTTGGTTAATCA
GTGTTTGATATAATTGAAAGAGTTGAGTGGATAAACAGTCTTCCAGCTTGTAAATGCCATTGACTTCTGACCTGACATTTAGTATAATAA
AAATGAAATTCTTAACCATGTCAAATGATTTAGTTTCTGGCTCTTAGACTCATCTGGCAGTTCTACACATGAAACATCTTTTGTTATATA
AGGTGTATTGAAACCTGCAGTGCTGATTATTAGAAAGGATTTGTCAGATTTTTGAACATGATATTTACATTATTATTTAGGAAAACTCTT
CCTGTAAATAACCATGCATAACTTACTTTCTGCAATGTTTTCTTAGAAATTGTGTCCAGATAGCTTTCACTAATTTTAAATTAAGTGAAC
TAAATATATATGTGTATATGTATACACATATATATACACACACACATATATATATTTAGAAACGTGAGTGTTAAAGATAGAATTTGTTTT
AGGACAAATTTTAAGAAAATGTGGGAATACCAAATGTCCTTTATAAGAAAAATAAATTTTATTTTAAGGGACATACTAGTTTTAGGGATT
TTCAGATGGGAAGCTGCATTTTTAGGATTGCCCATCTTAAGAGATCTTGCAGGAAGAGATTGTATTAGATATTATATTTATTTCATTTAA
GATAATTTTCAAAGTTAATTTTCTAAATAAGATAATTCTCATTTGTGTTTGTCTTTTAAAAGGCCAATAAAATATCTTTCAGTATCATTG
TAATAATTTTTTAGAGTTTAATTTGTAAAGCTTAGCAAATAAAATCTTGTACTATGAATAGCTTCTTGCTTTATGACTTTAGGATTAACT
TGTAAAAAACATATCCTGAACTGAGATATGCAAAATACTCATTTTCAAGTTATGGAAATGTGTTTGTGGCATATAGGACTGTGGGGTCTG
TGTGTGTAGTGAGAGTGTGTAGCCACTATTATAACTGGAATTTAATTTACATTCATAAACTACTATATTTCCCATCTTGCAAATCATTTT
ATGTCTCATCTGTTTTTCCTTTCGGTTATATCTTTGGTTTTGAATACCAACATTTAAAATGATGGTATTTTATCTTTTAAACTTAAAAAT
TATTTAATACAGCTATATGGACCTTATAAAATTGATTTCTTATTTATTATTAGACATTACTACTAAAAGGTACATCTAACTATTCAGGGA
CATTTTTCCATTTCCAAAAAATAAAATTTATTATGCTTTATAACCTCTTCTGTATTTTCTAATTTTTTCATTGTCTTTGATAAATAAAAC
AGTTTTGTTTTGCTAATATAGCCTATTTTTTGTTTTGTCTCATTCAGTTTACTTTCCTGCGTAGAATTTTTATTGTTATATTAAAATTTT
TATTGTTGTATTAAAGTACCTGTGTTACACCCCTTGAAGTAAGACAGTAGCATGGGGTAAAGAAAAAATATTTAGTTTAGTTGCCTAATT
TGGAAGTTAATTAAAATTAAACTGTACTAATAACATATTCAAACTCATGCTGGATCTCTTTCATATTAATTTCTTATAGACCTGTACTTT
ATTCTTTCAATAATTTTTAAATGAAATTAAGCTTTGCTACATGGTAATTAAATAATTACTAGGAAGCTTAGCTATCAAACATCGACTTAC
TAAAATTTCATTTTAGCTTTTATGGTATATGTGCTTGTTTTCTGAATATGGATACATGTTACTTTTGATCCAGCATCAAAACTTCACTTT
TTGTTTTGACTTTTCCCCCCAAATCTGTAAGGTTCAAGTATACATATTACTGAATCCTCTATAATTGGCATAATTCAATGGTAGCCTTAA
ATCTCATCATGTAAGCAGGGGAATCAGAATGTTATTTTCAAGAACTTAATGTTCCCTTCAGATATATAAAATCCTGCATACTTCATTTCC
TGTGAGCTTGAACAGCTGCTGTTGTGTTTTGGGGATGCTTGATCATCTTTGCACTCTGCCTTAAAGATTGAAAAATCAAAACTCTTGTTA
GGGTATCTAAACATTTTTGAGTGTGAACTGGGGATTGGAAGTTAATACAAAAAAATTTCAAATTATTTCTATTGTAAATGAATAAGCTAG
TCATGGCTAGGATAATCCATTTTCATGTATTTATGCAATAAACTGAATTTTAAGGCAAAAACAACACTTTTCTATATAGTGTATGCAGGA
CAGATTTTAGAAACTTAGATTAAAATACAAATCCCATTACATTTGGTTAAAATGAAAATCTCTGCTTAATGGAAAAAATACTAATCTTTA
GCCTATTTTGAGTCTATAAGATATATTTCATTTTAGACATGCCTTCTAAGTTGTTCACAGATTTTTACCTGCTAAAACAATATTATTTCC
AGTAAAACCTCTCCTAACAGGAAAAGTGGAGTTCAAAATATCCAATTGGAGAAAAATTCAGAGTTCCTTCATTAAATATAATTTTTTTCA
TCTAGTATGTACTATTTCAAGAAGTGCAAAAAGTAATGATAGTGAATGTGATACCATACTTAACTAAGGTAATATATATCCTTAGTTTGC
TCAAAAGAGTCCTGGTTATTCCTGTTTTCTCAGCTTAATAGTGCCTCATCGTACTCTCAAAAGTGTTCTAATTTGGAGGATAAGTTATAT
GATCATCCTGTGTATAATTGTAGACTGTACCAAGAAGCAACTACCTTAGCTCCACTGCCCTTTGAGGGATGGAACTGGGGTAAGGGCAGG
AGCCAGTTATTATTGCCACAGTGTTTTCTAATGAACCATTTGGCCTGTAGAAGAGGAATAGTATTTTTTTTAATAGTTGTATTTGAATGA
TTCCAGCTTATCGTAAATACTAAACTGAATGGCTTTTATATTTTTAACTGCTGTTAAATGTTATTTTAGCATTTATTAGTTGTTTATTAT
TTAATTCTTCAAATAGTCATATGAAAACATATATTTGATAAAGGTCAATTGTTAGATGATAATGTGCCATTCATTATCATAGGAATGTCC
TTGCCCATATATAAAACATGCTGGCATGTATTTTACTTGTTAATAAAGTTGTATAGATGTGGAAGTGTGAACCTGTGATGCATCCTTTTC
AAAATCAGTTTAAGATTCGCATATTATCATGACTGTGACCTCACTAAACTGTTTATGTGACAAACCTTTCAAGATTGGAGATGAAAACAA
CACTTGTGAAATTAGGTTGGGGTTGCAACATCTTTTAACTTCTCAGTTATTTGTATGTCAGGAGACAGATTGTGGTTTAATTTTAATAAA

>68659_68659_2_PRKAR1A-NDFIP2_PRKAR1A_chr17_66511717_ENST00000392711_NDFIP2_chr13_80094945_ENST00000218652_length(amino acids)=288AA_BP=48
MESGSTAASEEARSLRECELYVQKHNIQALLKDSIVQLCTARPERPMAFLREYFERLEKLLNEEDNSESSAIEQPPTSNPAPQIVQAASS
APALETDSSPPPYSSITVEVPTTSDTEVYGEFYPVPPPYSVATSLPTYDEAEKAKAAAMAAAAAETSQRIQEEECPPRDDFSDADQLRVG
NDGIFMLAFFMAFIFNWLGFCLSFCITNTIAGRYGAICGFGLSLIKWILIVRFSDYFTGYFNGQYWLWWIFLVLGLLLFFRGFVNYLKVR

--------------------------------------------------------------
>68659_68659_3_PRKAR1A-NDFIP2_PRKAR1A_chr17_66511717_ENST00000536854_NDFIP2_chr13_80094945_ENST00000218652_length(transcript)=4667nt_BP=415nt
ATCGCAGAGTGGAGCGGGGCTGGGAGCAAAGCGCTGAGGGAGCTCGGTACGCCGCCGCCTCGCACCCGCAGCCTCGCGCCCGCCGCCGCC
CGTCCCCAGTTGACTTTTGTGCCCTGGTAATTCTGTATCCTGTTTACCGTTTACCTACTTCCCACGTCATCATGATTTCTTTTGAGGGAG
AACTGAATGAAATTCCCTTAAGGGCCTGACTTCAGCACCCGTCTCTGCAGAGAGAACCATGGAGTCTGGCAGTACCGCCGCCAGTGAGGA
GGCACGCAGCCTTCGAGAATGTGAGCTCTACGTCCAGAAGCATAACATTCAAGCGCTGCTCAAAGATTCTATTGTGCAGTTGTGCACTGC
TCGACCTGAGAGACCCATGGCATTCCTCAGGGAATACTTTGAGAGGTTGGAGAAGCTTCTTAATGAAGAGGATAACTCAGAATCATCGGC
TATAGAGCAGCCACCTACTTCAAACCCAGCACCGCAGATTGTGCAGGCTGCGTCTTCAGCACCAGCACTTGAAACTGACTCTTCCCCTCC
ACCATATAGTAGTATTACTGTGGAAGTACCTACAACTTCAGATACAGAAGTTTACGGTGAGTTTTATCCCGTGCCACCTCCCTATAGCGT
TGCTACCTCTCTTCCTACATACGATGAAGCTGAGAAGGCTAAAGCTGCTGCAATGGCAGCTGCAGCAGCAGAAACATCTCAAAGAATTCA
GGAGGAAGAGTGTCCACCAAGAGATGACTTCAGTGATGCAGACCAGCTCAGAGTGGGGAATGATGGCATTTTCATGCTGGCATTTTTCAT
GGCATTTATTTTCAACTGGCTTGGATTTTGTTTATCCTTCTGTATCACCAATACCATAGCTGGAAGGTATGGTGCTATCTGCGGATTTGG
CCTTTCCTTGATCAAATGGATCCTTATTGTCAGGTTTTCTGATTATTTTACTGGATATTTCAATGGACAGTATTGGCTTTGGTGGATATT
TCTTGTACTTGGCCTGCTCCTTTTCTTCAGAGGATTTGTTAATTATCTAAAAGTCAGAAACATGTCTGAAAGTATGGCAGCTGCTCATAG
AACAAGGTATTTCTTCTTATTGTAGAGACTGCATCAACCCGACATTCCTTTCTTATACCAATGTGAAATTTCCAGATCATCTGTAAACCT
ACAACTTTAATAGAAGACTACTAATAACAGAAGACAAATTAGTGAAGAAAAGACGGAGTTTCGAAATTGAATGGCAGGGTGGTTTTTGCT
TACAAGCCATTTCTGTTCATTCTTTAAGTATCTATATTTCATTTGTTTTGCACATATGCATATGTGCCCATTTAAGATATTTGCATATAC
TTGATAGAAACCATAAAGTTGTAGCAGTTAAGTCCAGTCACATTTGGTTAATCAGTGTTTGATATAATTGAAAGAGTTGAGTGGATAAAC
AGTCTTCCAGCTTGTAAATGCCATTGACTTCTGACCTGACATTTAGTATAATAAAAATGAAATTCTTAACCATGTCAAATGATTTAGTTT
CTGGCTCTTAGACTCATCTGGCAGTTCTACACATGAAACATCTTTTGTTATATAAGGTGTATTGAAACCTGCAGTGCTGATTATTAGAAA
GGATTTGTCAGATTTTTGAACATGATATTTACATTATTATTTAGGAAAACTCTTCCTGTAAATAACCATGCATAACTTACTTTCTGCAAT
GTTTTCTTAGAAATTGTGTCCAGATAGCTTTCACTAATTTTAAATTAAGTGAACTAAATATATATGTGTATATGTATACACATATATATA
CACACACACATATATATATTTAGAAACGTGAGTGTTAAAGATAGAATTTGTTTTAGGACAAATTTTAAGAAAATGTGGGAATACCAAATG
TCCTTTATAAGAAAAATAAATTTTATTTTAAGGGACATACTAGTTTTAGGGATTTTCAGATGGGAAGCTGCATTTTTAGGATTGCCCATC
TTAAGAGATCTTGCAGGAAGAGATTGTATTAGATATTATATTTATTTCATTTAAGATAATTTTCAAAGTTAATTTTCTAAATAAGATAAT
TCTCATTTGTGTTTGTCTTTTAAAAGGCCAATAAAATATCTTTCAGTATCATTGTAATAATTTTTTAGAGTTTAATTTGTAAAGCTTAGC
AAATAAAATCTTGTACTATGAATAGCTTCTTGCTTTATGACTTTAGGATTAACTTGTAAAAAACATATCCTGAACTGAGATATGCAAAAT
ACTCATTTTCAAGTTATGGAAATGTGTTTGTGGCATATAGGACTGTGGGGTCTGTGTGTGTAGTGAGAGTGTGTAGCCACTATTATAACT
GGAATTTAATTTACATTCATAAACTACTATATTTCCCATCTTGCAAATCATTTTATGTCTCATCTGTTTTTCCTTTCGGTTATATCTTTG
GTTTTGAATACCAACATTTAAAATGATGGTATTTTATCTTTTAAACTTAAAAATTATTTAATACAGCTATATGGACCTTATAAAATTGAT
TTCTTATTTATTATTAGACATTACTACTAAAAGGTACATCTAACTATTCAGGGACATTTTTCCATTTCCAAAAAATAAAATTTATTATGC
TTTATAACCTCTTCTGTATTTTCTAATTTTTTCATTGTCTTTGATAAATAAAACAGTTTTGTTTTGCTAATATAGCCTATTTTTTGTTTT
GTCTCATTCAGTTTACTTTCCTGCGTAGAATTTTTATTGTTATATTAAAATTTTTATTGTTGTATTAAAGTACCTGTGTTACACCCCTTG
AAGTAAGACAGTAGCATGGGGTAAAGAAAAAATATTTAGTTTAGTTGCCTAATTTGGAAGTTAATTAAAATTAAACTGTACTAATAACAT
ATTCAAACTCATGCTGGATCTCTTTCATATTAATTTCTTATAGACCTGTACTTTATTCTTTCAATAATTTTTAAATGAAATTAAGCTTTG
CTACATGGTAATTAAATAATTACTAGGAAGCTTAGCTATCAAACATCGACTTACTAAAATTTCATTTTAGCTTTTATGGTATATGTGCTT
GTTTTCTGAATATGGATACATGTTACTTTTGATCCAGCATCAAAACTTCACTTTTTGTTTTGACTTTTCCCCCCAAATCTGTAAGGTTCA
AGTATACATATTACTGAATCCTCTATAATTGGCATAATTCAATGGTAGCCTTAAATCTCATCATGTAAGCAGGGGAATCAGAATGTTATT
TTCAAGAACTTAATGTTCCCTTCAGATATATAAAATCCTGCATACTTCATTTCCTGTGAGCTTGAACAGCTGCTGTTGTGTTTTGGGGAT
GCTTGATCATCTTTGCACTCTGCCTTAAAGATTGAAAAATCAAAACTCTTGTTAGGGTATCTAAACATTTTTGAGTGTGAACTGGGGATT
GGAAGTTAATACAAAAAAATTTCAAATTATTTCTATTGTAAATGAATAAGCTAGTCATGGCTAGGATAATCCATTTTCATGTATTTATGC
AATAAACTGAATTTTAAGGCAAAAACAACACTTTTCTATATAGTGTATGCAGGACAGATTTTAGAAACTTAGATTAAAATACAAATCCCA
TTACATTTGGTTAAAATGAAAATCTCTGCTTAATGGAAAAAATACTAATCTTTAGCCTATTTTGAGTCTATAAGATATATTTCATTTTAG
ACATGCCTTCTAAGTTGTTCACAGATTTTTACCTGCTAAAACAATATTATTTCCAGTAAAACCTCTCCTAACAGGAAAAGTGGAGTTCAA
AATATCCAATTGGAGAAAAATTCAGAGTTCCTTCATTAAATATAATTTTTTTCATCTAGTATGTACTATTTCAAGAAGTGCAAAAAGTAA
TGATAGTGAATGTGATACCATACTTAACTAAGGTAATATATATCCTTAGTTTGCTCAAAAGAGTCCTGGTTATTCCTGTTTTCTCAGCTT
AATAGTGCCTCATCGTACTCTCAAAAGTGTTCTAATTTGGAGGATAAGTTATATGATCATCCTGTGTATAATTGTAGACTGTACCAAGAA
GCAACTACCTTAGCTCCACTGCCCTTTGAGGGATGGAACTGGGGTAAGGGCAGGAGCCAGTTATTATTGCCACAGTGTTTTCTAATGAAC
CATTTGGCCTGTAGAAGAGGAATAGTATTTTTTTTAATAGTTGTATTTGAATGATTCCAGCTTATCGTAAATACTAAACTGAATGGCTTT
TATATTTTTAACTGCTGTTAAATGTTATTTTAGCATTTATTAGTTGTTTATTATTTAATTCTTCAAATAGTCATATGAAAACATATATTT
GATAAAGGTCAATTGTTAGATGATAATGTGCCATTCATTATCATAGGAATGTCCTTGCCCATATATAAAACATGCTGGCATGTATTTTAC
TTGTTAATAAAGTTGTATAGATGTGGAAGTGTGAACCTGTGATGCATCCTTTTCAAAATCAGTTTAAGATTCGCATATTATCATGACTGT
GACCTCACTAAACTGTTTATGTGACAAACCTTTCAAGATTGGAGATGAAAACAACACTTGTGAAATTAGGTTGGGGTTGCAACATCTTTT

>68659_68659_3_PRKAR1A-NDFIP2_PRKAR1A_chr17_66511717_ENST00000536854_NDFIP2_chr13_80094945_ENST00000218652_length(amino acids)=299AA_BP=59
MTSAPVSAERTMESGSTAASEEARSLRECELYVQKHNIQALLKDSIVQLCTARPERPMAFLREYFERLEKLLNEEDNSESSAIEQPPTSN
PAPQIVQAASSAPALETDSSPPPYSSITVEVPTTSDTEVYGEFYPVPPPYSVATSLPTYDEAEKAKAAAMAAAAAETSQRIQEEECPPRD
DFSDADQLRVGNDGIFMLAFFMAFIFNWLGFCLSFCITNTIAGRYGAICGFGLSLIKWILIVRFSDYFTGYFNGQYWLWWIFLVLGLLLF

--------------------------------------------------------------
>68659_68659_4_PRKAR1A-NDFIP2_PRKAR1A_chr17_66511717_ENST00000586397_NDFIP2_chr13_80094945_ENST00000218652_length(transcript)=5008nt_BP=756nt
TAATTTTCTTGTGTGTTTTTAAAAATTTTGATTATGCTAGTAGTTGGCTAATCAGATCCTCACTCCAGTGGTTTGCTCTGTGACGTTAGG
ATACTCCCATGGGATAGAAGTTACGTATAGGGAATGTCAGATATTCTTCATTGTGCTGACTTGCTTTCGCTTACAGTTGACTTTTGTGCC
CTGGTAATTCTGTATCCTGTTTACCGTTTACCTACTTCCCACGTCATCATGATTTCTTTTGAGGGAGAACTGAATGAAATTCCCTTAAGG
GCCTGACTTCAGCACCCGTCTCTGCAGAGGTTAGTGGCTCATACTTCCTCCCAGGAGCTGAGGTTATCGACTCTCACTGTTGCCTACAGA
GCACAGATCCTGAACTAAATGAAACATTTACTTGGAATAATGCTAATTCTGTACATATTTTATTCCCTAGTCCCCACTTCCCTGTTTAAA
AACAAAATCTACTTAGAAAAAAATCCCTGTGAATCAGTTGTCTAATGAATTTAGCAAGTTAAATGCCAGATTGACATTTTGCTTTATAGT
TTATACAAGCATGTGTGTGTTTTTTTCTCGCAGAGAACCATGGAGTCTGGCAGTACCGCCGCCAGTGAGGAGGCACGCAGCCTTCGAGAA
TGTGAGCTCTACGTCCAGAAGCATAACATTCAAGCGCTGCTCAAAGATTCTATTGTGCAGTTGTGCACTGCTCGACCTGAGAGACCCATG
GCATTCCTCAGGGAATACTTTGAGAGGTTGGAGAAGCTTCTTAATGAAGAGGATAACTCAGAATCATCGGCTATAGAGCAGCCACCTACT
TCAAACCCAGCACCGCAGATTGTGCAGGCTGCGTCTTCAGCACCAGCACTTGAAACTGACTCTTCCCCTCCACCATATAGTAGTATTACT
GTGGAAGTACCTACAACTTCAGATACAGAAGTTTACGGTGAGTTTTATCCCGTGCCACCTCCCTATAGCGTTGCTACCTCTCTTCCTACA
TACGATGAAGCTGAGAAGGCTAAAGCTGCTGCAATGGCAGCTGCAGCAGCAGAAACATCTCAAAGAATTCAGGAGGAAGAGTGTCCACCA
AGAGATGACTTCAGTGATGCAGACCAGCTCAGAGTGGGGAATGATGGCATTTTCATGCTGGCATTTTTCATGGCATTTATTTTCAACTGG
CTTGGATTTTGTTTATCCTTCTGTATCACCAATACCATAGCTGGAAGGTATGGTGCTATCTGCGGATTTGGCCTTTCCTTGATCAAATGG
ATCCTTATTGTCAGGTTTTCTGATTATTTTACTGGATATTTCAATGGACAGTATTGGCTTTGGTGGATATTTCTTGTACTTGGCCTGCTC
CTTTTCTTCAGAGGATTTGTTAATTATCTAAAAGTCAGAAACATGTCTGAAAGTATGGCAGCTGCTCATAGAACAAGGTATTTCTTCTTA
TTGTAGAGACTGCATCAACCCGACATTCCTTTCTTATACCAATGTGAAATTTCCAGATCATCTGTAAACCTACAACTTTAATAGAAGACT
ACTAATAACAGAAGACAAATTAGTGAAGAAAAGACGGAGTTTCGAAATTGAATGGCAGGGTGGTTTTTGCTTACAAGCCATTTCTGTTCA
TTCTTTAAGTATCTATATTTCATTTGTTTTGCACATATGCATATGTGCCCATTTAAGATATTTGCATATACTTGATAGAAACCATAAAGT
TGTAGCAGTTAAGTCCAGTCACATTTGGTTAATCAGTGTTTGATATAATTGAAAGAGTTGAGTGGATAAACAGTCTTCCAGCTTGTAAAT
GCCATTGACTTCTGACCTGACATTTAGTATAATAAAAATGAAATTCTTAACCATGTCAAATGATTTAGTTTCTGGCTCTTAGACTCATCT
GGCAGTTCTACACATGAAACATCTTTTGTTATATAAGGTGTATTGAAACCTGCAGTGCTGATTATTAGAAAGGATTTGTCAGATTTTTGA
ACATGATATTTACATTATTATTTAGGAAAACTCTTCCTGTAAATAACCATGCATAACTTACTTTCTGCAATGTTTTCTTAGAAATTGTGT
CCAGATAGCTTTCACTAATTTTAAATTAAGTGAACTAAATATATATGTGTATATGTATACACATATATATACACACACACATATATATAT
TTAGAAACGTGAGTGTTAAAGATAGAATTTGTTTTAGGACAAATTTTAAGAAAATGTGGGAATACCAAATGTCCTTTATAAGAAAAATAA
ATTTTATTTTAAGGGACATACTAGTTTTAGGGATTTTCAGATGGGAAGCTGCATTTTTAGGATTGCCCATCTTAAGAGATCTTGCAGGAA
GAGATTGTATTAGATATTATATTTATTTCATTTAAGATAATTTTCAAAGTTAATTTTCTAAATAAGATAATTCTCATTTGTGTTTGTCTT
TTAAAAGGCCAATAAAATATCTTTCAGTATCATTGTAATAATTTTTTAGAGTTTAATTTGTAAAGCTTAGCAAATAAAATCTTGTACTAT
GAATAGCTTCTTGCTTTATGACTTTAGGATTAACTTGTAAAAAACATATCCTGAACTGAGATATGCAAAATACTCATTTTCAAGTTATGG
AAATGTGTTTGTGGCATATAGGACTGTGGGGTCTGTGTGTGTAGTGAGAGTGTGTAGCCACTATTATAACTGGAATTTAATTTACATTCA
TAAACTACTATATTTCCCATCTTGCAAATCATTTTATGTCTCATCTGTTTTTCCTTTCGGTTATATCTTTGGTTTTGAATACCAACATTT
AAAATGATGGTATTTTATCTTTTAAACTTAAAAATTATTTAATACAGCTATATGGACCTTATAAAATTGATTTCTTATTTATTATTAGAC
ATTACTACTAAAAGGTACATCTAACTATTCAGGGACATTTTTCCATTTCCAAAAAATAAAATTTATTATGCTTTATAACCTCTTCTGTAT
TTTCTAATTTTTTCATTGTCTTTGATAAATAAAACAGTTTTGTTTTGCTAATATAGCCTATTTTTTGTTTTGTCTCATTCAGTTTACTTT
CCTGCGTAGAATTTTTATTGTTATATTAAAATTTTTATTGTTGTATTAAAGTACCTGTGTTACACCCCTTGAAGTAAGACAGTAGCATGG
GGTAAAGAAAAAATATTTAGTTTAGTTGCCTAATTTGGAAGTTAATTAAAATTAAACTGTACTAATAACATATTCAAACTCATGCTGGAT
CTCTTTCATATTAATTTCTTATAGACCTGTACTTTATTCTTTCAATAATTTTTAAATGAAATTAAGCTTTGCTACATGGTAATTAAATAA
TTACTAGGAAGCTTAGCTATCAAACATCGACTTACTAAAATTTCATTTTAGCTTTTATGGTATATGTGCTTGTTTTCTGAATATGGATAC
ATGTTACTTTTGATCCAGCATCAAAACTTCACTTTTTGTTTTGACTTTTCCCCCCAAATCTGTAAGGTTCAAGTATACATATTACTGAAT
CCTCTATAATTGGCATAATTCAATGGTAGCCTTAAATCTCATCATGTAAGCAGGGGAATCAGAATGTTATTTTCAAGAACTTAATGTTCC
CTTCAGATATATAAAATCCTGCATACTTCATTTCCTGTGAGCTTGAACAGCTGCTGTTGTGTTTTGGGGATGCTTGATCATCTTTGCACT
CTGCCTTAAAGATTGAAAAATCAAAACTCTTGTTAGGGTATCTAAACATTTTTGAGTGTGAACTGGGGATTGGAAGTTAATACAAAAAAA
TTTCAAATTATTTCTATTGTAAATGAATAAGCTAGTCATGGCTAGGATAATCCATTTTCATGTATTTATGCAATAAACTGAATTTTAAGG
CAAAAACAACACTTTTCTATATAGTGTATGCAGGACAGATTTTAGAAACTTAGATTAAAATACAAATCCCATTACATTTGGTTAAAATGA
AAATCTCTGCTTAATGGAAAAAATACTAATCTTTAGCCTATTTTGAGTCTATAAGATATATTTCATTTTAGACATGCCTTCTAAGTTGTT
CACAGATTTTTACCTGCTAAAACAATATTATTTCCAGTAAAACCTCTCCTAACAGGAAAAGTGGAGTTCAAAATATCCAATTGGAGAAAA
ATTCAGAGTTCCTTCATTAAATATAATTTTTTTCATCTAGTATGTACTATTTCAAGAAGTGCAAAAAGTAATGATAGTGAATGTGATACC
ATACTTAACTAAGGTAATATATATCCTTAGTTTGCTCAAAAGAGTCCTGGTTATTCCTGTTTTCTCAGCTTAATAGTGCCTCATCGTACT
CTCAAAAGTGTTCTAATTTGGAGGATAAGTTATATGATCATCCTGTGTATAATTGTAGACTGTACCAAGAAGCAACTACCTTAGCTCCAC
TGCCCTTTGAGGGATGGAACTGGGGTAAGGGCAGGAGCCAGTTATTATTGCCACAGTGTTTTCTAATGAACCATTTGGCCTGTAGAAGAG
GAATAGTATTTTTTTTAATAGTTGTATTTGAATGATTCCAGCTTATCGTAAATACTAAACTGAATGGCTTTTATATTTTTAACTGCTGTT
AAATGTTATTTTAGCATTTATTAGTTGTTTATTATTTAATTCTTCAAATAGTCATATGAAAACATATATTTGATAAAGGTCAATTGTTAG
ATGATAATGTGCCATTCATTATCATAGGAATGTCCTTGCCCATATATAAAACATGCTGGCATGTATTTTACTTGTTAATAAAGTTGTATA
GATGTGGAAGTGTGAACCTGTGATGCATCCTTTTCAAAATCAGTTTAAGATTCGCATATTATCATGACTGTGACCTCACTAAACTGTTTA
TGTGACAAACCTTTCAAGATTGGAGATGAAAACAACACTTGTGAAATTAGGTTGGGGTTGCAACATCTTTTAACTTCTCAGTTATTTGTA

>68659_68659_4_PRKAR1A-NDFIP2_PRKAR1A_chr17_66511717_ENST00000586397_NDFIP2_chr13_80094945_ENST00000218652_length(amino acids)=305AA_BP=65
MLYSLYKHVCVFFSQRTMESGSTAASEEARSLRECELYVQKHNIQALLKDSIVQLCTARPERPMAFLREYFERLEKLLNEEDNSESSAIE
QPPTSNPAPQIVQAASSAPALETDSSPPPYSSITVEVPTTSDTEVYGEFYPVPPPYSVATSLPTYDEAEKAKAAAMAAAAAETSQRIQEE
ECPPRDDFSDADQLRVGNDGIFMLAFFMAFIFNWLGFCLSFCITNTIAGRYGAICGFGLSLIKWILIVRFSDYFTGYFNGQYWLWWIFLV

--------------------------------------------------------------
>68659_68659_5_PRKAR1A-NDFIP2_PRKAR1A_chr17_66511717_ENST00000588188_NDFIP2_chr13_80094945_ENST00000218652_length(transcript)=4429nt_BP=177nt
ATGGAGTCTGGCAGTACCGCCGCCAGTGAGGAGGCACGCAGCCTTCGAGAATGTGAGCTCTACGTCCAGAAGCATAACATTCAAGCGCTG
CTCAAAGATTCTATTGTGCAGTTGTGCACTGCTCGACCTGAGAGACCCATGGCATTCCTCAGGGAATACTTTGAGAGGTTGGAGAAGCTT
CTTAATGAAGAGGATAACTCAGAATCATCGGCTATAGAGCAGCCACCTACTTCAAACCCAGCACCGCAGATTGTGCAGGCTGCGTCTTCA
GCACCAGCACTTGAAACTGACTCTTCCCCTCCACCATATAGTAGTATTACTGTGGAAGTACCTACAACTTCAGATACAGAAGTTTACGGT
GAGTTTTATCCCGTGCCACCTCCCTATAGCGTTGCTACCTCTCTTCCTACATACGATGAAGCTGAGAAGGCTAAAGCTGCTGCAATGGCA
GCTGCAGCAGCAGAAACATCTCAAAGAATTCAGGAGGAAGAGTGTCCACCAAGAGATGACTTCAGTGATGCAGACCAGCTCAGAGTGGGG
AATGATGGCATTTTCATGCTGGCATTTTTCATGGCATTTATTTTCAACTGGCTTGGATTTTGTTTATCCTTCTGTATCACCAATACCATA
GCTGGAAGGTATGGTGCTATCTGCGGATTTGGCCTTTCCTTGATCAAATGGATCCTTATTGTCAGGTTTTCTGATTATTTTACTGGATAT
TTCAATGGACAGTATTGGCTTTGGTGGATATTTCTTGTACTTGGCCTGCTCCTTTTCTTCAGAGGATTTGTTAATTATCTAAAAGTCAGA
AACATGTCTGAAAGTATGGCAGCTGCTCATAGAACAAGGTATTTCTTCTTATTGTAGAGACTGCATCAACCCGACATTCCTTTCTTATAC
CAATGTGAAATTTCCAGATCATCTGTAAACCTACAACTTTAATAGAAGACTACTAATAACAGAAGACAAATTAGTGAAGAAAAGACGGAG
TTTCGAAATTGAATGGCAGGGTGGTTTTTGCTTACAAGCCATTTCTGTTCATTCTTTAAGTATCTATATTTCATTTGTTTTGCACATATG
CATATGTGCCCATTTAAGATATTTGCATATACTTGATAGAAACCATAAAGTTGTAGCAGTTAAGTCCAGTCACATTTGGTTAATCAGTGT
TTGATATAATTGAAAGAGTTGAGTGGATAAACAGTCTTCCAGCTTGTAAATGCCATTGACTTCTGACCTGACATTTAGTATAATAAAAAT
GAAATTCTTAACCATGTCAAATGATTTAGTTTCTGGCTCTTAGACTCATCTGGCAGTTCTACACATGAAACATCTTTTGTTATATAAGGT
GTATTGAAACCTGCAGTGCTGATTATTAGAAAGGATTTGTCAGATTTTTGAACATGATATTTACATTATTATTTAGGAAAACTCTTCCTG
TAAATAACCATGCATAACTTACTTTCTGCAATGTTTTCTTAGAAATTGTGTCCAGATAGCTTTCACTAATTTTAAATTAAGTGAACTAAA
TATATATGTGTATATGTATACACATATATATACACACACACATATATATATTTAGAAACGTGAGTGTTAAAGATAGAATTTGTTTTAGGA
CAAATTTTAAGAAAATGTGGGAATACCAAATGTCCTTTATAAGAAAAATAAATTTTATTTTAAGGGACATACTAGTTTTAGGGATTTTCA
GATGGGAAGCTGCATTTTTAGGATTGCCCATCTTAAGAGATCTTGCAGGAAGAGATTGTATTAGATATTATATTTATTTCATTTAAGATA
ATTTTCAAAGTTAATTTTCTAAATAAGATAATTCTCATTTGTGTTTGTCTTTTAAAAGGCCAATAAAATATCTTTCAGTATCATTGTAAT
AATTTTTTAGAGTTTAATTTGTAAAGCTTAGCAAATAAAATCTTGTACTATGAATAGCTTCTTGCTTTATGACTTTAGGATTAACTTGTA
AAAAACATATCCTGAACTGAGATATGCAAAATACTCATTTTCAAGTTATGGAAATGTGTTTGTGGCATATAGGACTGTGGGGTCTGTGTG
TGTAGTGAGAGTGTGTAGCCACTATTATAACTGGAATTTAATTTACATTCATAAACTACTATATTTCCCATCTTGCAAATCATTTTATGT
CTCATCTGTTTTTCCTTTCGGTTATATCTTTGGTTTTGAATACCAACATTTAAAATGATGGTATTTTATCTTTTAAACTTAAAAATTATT
TAATACAGCTATATGGACCTTATAAAATTGATTTCTTATTTATTATTAGACATTACTACTAAAAGGTACATCTAACTATTCAGGGACATT
TTTCCATTTCCAAAAAATAAAATTTATTATGCTTTATAACCTCTTCTGTATTTTCTAATTTTTTCATTGTCTTTGATAAATAAAACAGTT
TTGTTTTGCTAATATAGCCTATTTTTTGTTTTGTCTCATTCAGTTTACTTTCCTGCGTAGAATTTTTATTGTTATATTAAAATTTTTATT
GTTGTATTAAAGTACCTGTGTTACACCCCTTGAAGTAAGACAGTAGCATGGGGTAAAGAAAAAATATTTAGTTTAGTTGCCTAATTTGGA
AGTTAATTAAAATTAAACTGTACTAATAACATATTCAAACTCATGCTGGATCTCTTTCATATTAATTTCTTATAGACCTGTACTTTATTC
TTTCAATAATTTTTAAATGAAATTAAGCTTTGCTACATGGTAATTAAATAATTACTAGGAAGCTTAGCTATCAAACATCGACTTACTAAA
ATTTCATTTTAGCTTTTATGGTATATGTGCTTGTTTTCTGAATATGGATACATGTTACTTTTGATCCAGCATCAAAACTTCACTTTTTGT
TTTGACTTTTCCCCCCAAATCTGTAAGGTTCAAGTATACATATTACTGAATCCTCTATAATTGGCATAATTCAATGGTAGCCTTAAATCT
CATCATGTAAGCAGGGGAATCAGAATGTTATTTTCAAGAACTTAATGTTCCCTTCAGATATATAAAATCCTGCATACTTCATTTCCTGTG
AGCTTGAACAGCTGCTGTTGTGTTTTGGGGATGCTTGATCATCTTTGCACTCTGCCTTAAAGATTGAAAAATCAAAACTCTTGTTAGGGT
ATCTAAACATTTTTGAGTGTGAACTGGGGATTGGAAGTTAATACAAAAAAATTTCAAATTATTTCTATTGTAAATGAATAAGCTAGTCAT
GGCTAGGATAATCCATTTTCATGTATTTATGCAATAAACTGAATTTTAAGGCAAAAACAACACTTTTCTATATAGTGTATGCAGGACAGA
TTTTAGAAACTTAGATTAAAATACAAATCCCATTACATTTGGTTAAAATGAAAATCTCTGCTTAATGGAAAAAATACTAATCTTTAGCCT
ATTTTGAGTCTATAAGATATATTTCATTTTAGACATGCCTTCTAAGTTGTTCACAGATTTTTACCTGCTAAAACAATATTATTTCCAGTA
AAACCTCTCCTAACAGGAAAAGTGGAGTTCAAAATATCCAATTGGAGAAAAATTCAGAGTTCCTTCATTAAATATAATTTTTTTCATCTA
GTATGTACTATTTCAAGAAGTGCAAAAAGTAATGATAGTGAATGTGATACCATACTTAACTAAGGTAATATATATCCTTAGTTTGCTCAA
AAGAGTCCTGGTTATTCCTGTTTTCTCAGCTTAATAGTGCCTCATCGTACTCTCAAAAGTGTTCTAATTTGGAGGATAAGTTATATGATC
ATCCTGTGTATAATTGTAGACTGTACCAAGAAGCAACTACCTTAGCTCCACTGCCCTTTGAGGGATGGAACTGGGGTAAGGGCAGGAGCC
AGTTATTATTGCCACAGTGTTTTCTAATGAACCATTTGGCCTGTAGAAGAGGAATAGTATTTTTTTTAATAGTTGTATTTGAATGATTCC
AGCTTATCGTAAATACTAAACTGAATGGCTTTTATATTTTTAACTGCTGTTAAATGTTATTTTAGCATTTATTAGTTGTTTATTATTTAA
TTCTTCAAATAGTCATATGAAAACATATATTTGATAAAGGTCAATTGTTAGATGATAATGTGCCATTCATTATCATAGGAATGTCCTTGC
CCATATATAAAACATGCTGGCATGTATTTTACTTGTTAATAAAGTTGTATAGATGTGGAAGTGTGAACCTGTGATGCATCCTTTTCAAAA
TCAGTTTAAGATTCGCATATTATCATGACTGTGACCTCACTAAACTGTTTATGTGACAAACCTTTCAAGATTGGAGATGAAAACAACACT
TGTGAAATTAGGTTGGGGTTGCAACATCTTTTAACTTCTCAGTTATTTGTATGTCAGGAGACAGATTGTGGTTTAATTTTAATAAACAAA

>68659_68659_5_PRKAR1A-NDFIP2_PRKAR1A_chr17_66511717_ENST00000588188_NDFIP2_chr13_80094945_ENST00000218652_length(amino acids)=288AA_BP=48
MESGSTAASEEARSLRECELYVQKHNIQALLKDSIVQLCTARPERPMAFLREYFERLEKLLNEEDNSESSAIEQPPTSNPAPQIVQAASS
APALETDSSPPPYSSITVEVPTTSDTEVYGEFYPVPPPYSVATSLPTYDEAEKAKAAAMAAAAAETSQRIQEEECPPRDDFSDADQLRVG
NDGIFMLAFFMAFIFNWLGFCLSFCITNTIAGRYGAICGFGLSLIKWILIVRFSDYFTGYFNGQYWLWWIFLVLGLLLFFRGFVNYLKVR

--------------------------------------------------------------
>68659_68659_6_PRKAR1A-NDFIP2_PRKAR1A_chr17_66511717_ENST00000589228_NDFIP2_chr13_80094945_ENST00000218652_length(transcript)=4557nt_BP=305nt
GGTGGAGCTGTCGCCTAGCCGCTATCGCAGAGTGGAGCGGGGCTGGGAGCAAAGCGCTGAGGGAGCTCGGTACGCCGCCGCCTCGCACCC
GCAGCCTCGCGCCCGCCGCCGCCCGTCCCCAGAGAACCATGGAGTCTGGCAGTACCGCCGCCAGTGAGGAGGCACGCAGCCTTCGAGAAT
GTGAGCTCTACGTCCAGAAGCATAACATTCAAGCGCTGCTCAAAGATTCTATTGTGCAGTTGTGCACTGCTCGACCTGAGAGACCCATGG
CATTCCTCAGGGAATACTTTGAGAGGTTGGAGAAGCTTCTTAATGAAGAGGATAACTCAGAATCATCGGCTATAGAGCAGCCACCTACTT
CAAACCCAGCACCGCAGATTGTGCAGGCTGCGTCTTCAGCACCAGCACTTGAAACTGACTCTTCCCCTCCACCATATAGTAGTATTACTG
TGGAAGTACCTACAACTTCAGATACAGAAGTTTACGGTGAGTTTTATCCCGTGCCACCTCCCTATAGCGTTGCTACCTCTCTTCCTACAT
ACGATGAAGCTGAGAAGGCTAAAGCTGCTGCAATGGCAGCTGCAGCAGCAGAAACATCTCAAAGAATTCAGGAGGAAGAGTGTCCACCAA
GAGATGACTTCAGTGATGCAGACCAGCTCAGAGTGGGGAATGATGGCATTTTCATGCTGGCATTTTTCATGGCATTTATTTTCAACTGGC
TTGGATTTTGTTTATCCTTCTGTATCACCAATACCATAGCTGGAAGGTATGGTGCTATCTGCGGATTTGGCCTTTCCTTGATCAAATGGA
TCCTTATTGTCAGGTTTTCTGATTATTTTACTGGATATTTCAATGGACAGTATTGGCTTTGGTGGATATTTCTTGTACTTGGCCTGCTCC
TTTTCTTCAGAGGATTTGTTAATTATCTAAAAGTCAGAAACATGTCTGAAAGTATGGCAGCTGCTCATAGAACAAGGTATTTCTTCTTAT
TGTAGAGACTGCATCAACCCGACATTCCTTTCTTATACCAATGTGAAATTTCCAGATCATCTGTAAACCTACAACTTTAATAGAAGACTA
CTAATAACAGAAGACAAATTAGTGAAGAAAAGACGGAGTTTCGAAATTGAATGGCAGGGTGGTTTTTGCTTACAAGCCATTTCTGTTCAT
TCTTTAAGTATCTATATTTCATTTGTTTTGCACATATGCATATGTGCCCATTTAAGATATTTGCATATACTTGATAGAAACCATAAAGTT
GTAGCAGTTAAGTCCAGTCACATTTGGTTAATCAGTGTTTGATATAATTGAAAGAGTTGAGTGGATAAACAGTCTTCCAGCTTGTAAATG
CCATTGACTTCTGACCTGACATTTAGTATAATAAAAATGAAATTCTTAACCATGTCAAATGATTTAGTTTCTGGCTCTTAGACTCATCTG
GCAGTTCTACACATGAAACATCTTTTGTTATATAAGGTGTATTGAAACCTGCAGTGCTGATTATTAGAAAGGATTTGTCAGATTTTTGAA
CATGATATTTACATTATTATTTAGGAAAACTCTTCCTGTAAATAACCATGCATAACTTACTTTCTGCAATGTTTTCTTAGAAATTGTGTC
CAGATAGCTTTCACTAATTTTAAATTAAGTGAACTAAATATATATGTGTATATGTATACACATATATATACACACACACATATATATATT
TAGAAACGTGAGTGTTAAAGATAGAATTTGTTTTAGGACAAATTTTAAGAAAATGTGGGAATACCAAATGTCCTTTATAAGAAAAATAAA
TTTTATTTTAAGGGACATACTAGTTTTAGGGATTTTCAGATGGGAAGCTGCATTTTTAGGATTGCCCATCTTAAGAGATCTTGCAGGAAG
AGATTGTATTAGATATTATATTTATTTCATTTAAGATAATTTTCAAAGTTAATTTTCTAAATAAGATAATTCTCATTTGTGTTTGTCTTT
TAAAAGGCCAATAAAATATCTTTCAGTATCATTGTAATAATTTTTTAGAGTTTAATTTGTAAAGCTTAGCAAATAAAATCTTGTACTATG
AATAGCTTCTTGCTTTATGACTTTAGGATTAACTTGTAAAAAACATATCCTGAACTGAGATATGCAAAATACTCATTTTCAAGTTATGGA
AATGTGTTTGTGGCATATAGGACTGTGGGGTCTGTGTGTGTAGTGAGAGTGTGTAGCCACTATTATAACTGGAATTTAATTTACATTCAT
AAACTACTATATTTCCCATCTTGCAAATCATTTTATGTCTCATCTGTTTTTCCTTTCGGTTATATCTTTGGTTTTGAATACCAACATTTA
AAATGATGGTATTTTATCTTTTAAACTTAAAAATTATTTAATACAGCTATATGGACCTTATAAAATTGATTTCTTATTTATTATTAGACA
TTACTACTAAAAGGTACATCTAACTATTCAGGGACATTTTTCCATTTCCAAAAAATAAAATTTATTATGCTTTATAACCTCTTCTGTATT
TTCTAATTTTTTCATTGTCTTTGATAAATAAAACAGTTTTGTTTTGCTAATATAGCCTATTTTTTGTTTTGTCTCATTCAGTTTACTTTC
CTGCGTAGAATTTTTATTGTTATATTAAAATTTTTATTGTTGTATTAAAGTACCTGTGTTACACCCCTTGAAGTAAGACAGTAGCATGGG
GTAAAGAAAAAATATTTAGTTTAGTTGCCTAATTTGGAAGTTAATTAAAATTAAACTGTACTAATAACATATTCAAACTCATGCTGGATC
TCTTTCATATTAATTTCTTATAGACCTGTACTTTATTCTTTCAATAATTTTTAAATGAAATTAAGCTTTGCTACATGGTAATTAAATAAT
TACTAGGAAGCTTAGCTATCAAACATCGACTTACTAAAATTTCATTTTAGCTTTTATGGTATATGTGCTTGTTTTCTGAATATGGATACA
TGTTACTTTTGATCCAGCATCAAAACTTCACTTTTTGTTTTGACTTTTCCCCCCAAATCTGTAAGGTTCAAGTATACATATTACTGAATC
CTCTATAATTGGCATAATTCAATGGTAGCCTTAAATCTCATCATGTAAGCAGGGGAATCAGAATGTTATTTTCAAGAACTTAATGTTCCC
TTCAGATATATAAAATCCTGCATACTTCATTTCCTGTGAGCTTGAACAGCTGCTGTTGTGTTTTGGGGATGCTTGATCATCTTTGCACTC
TGCCTTAAAGATTGAAAAATCAAAACTCTTGTTAGGGTATCTAAACATTTTTGAGTGTGAACTGGGGATTGGAAGTTAATACAAAAAAAT
TTCAAATTATTTCTATTGTAAATGAATAAGCTAGTCATGGCTAGGATAATCCATTTTCATGTATTTATGCAATAAACTGAATTTTAAGGC
AAAAACAACACTTTTCTATATAGTGTATGCAGGACAGATTTTAGAAACTTAGATTAAAATACAAATCCCATTACATTTGGTTAAAATGAA
AATCTCTGCTTAATGGAAAAAATACTAATCTTTAGCCTATTTTGAGTCTATAAGATATATTTCATTTTAGACATGCCTTCTAAGTTGTTC
ACAGATTTTTACCTGCTAAAACAATATTATTTCCAGTAAAACCTCTCCTAACAGGAAAAGTGGAGTTCAAAATATCCAATTGGAGAAAAA
TTCAGAGTTCCTTCATTAAATATAATTTTTTTCATCTAGTATGTACTATTTCAAGAAGTGCAAAAAGTAATGATAGTGAATGTGATACCA
TACTTAACTAAGGTAATATATATCCTTAGTTTGCTCAAAAGAGTCCTGGTTATTCCTGTTTTCTCAGCTTAATAGTGCCTCATCGTACTC
TCAAAAGTGTTCTAATTTGGAGGATAAGTTATATGATCATCCTGTGTATAATTGTAGACTGTACCAAGAAGCAACTACCTTAGCTCCACT
GCCCTTTGAGGGATGGAACTGGGGTAAGGGCAGGAGCCAGTTATTATTGCCACAGTGTTTTCTAATGAACCATTTGGCCTGTAGAAGAGG
AATAGTATTTTTTTTAATAGTTGTATTTGAATGATTCCAGCTTATCGTAAATACTAAACTGAATGGCTTTTATATTTTTAACTGCTGTTA
AATGTTATTTTAGCATTTATTAGTTGTTTATTATTTAATTCTTCAAATAGTCATATGAAAACATATATTTGATAAAGGTCAATTGTTAGA
TGATAATGTGCCATTCATTATCATAGGAATGTCCTTGCCCATATATAAAACATGCTGGCATGTATTTTACTTGTTAATAAAGTTGTATAG
ATGTGGAAGTGTGAACCTGTGATGCATCCTTTTCAAAATCAGTTTAAGATTCGCATATTATCATGACTGTGACCTCACTAAACTGTTTAT
GTGACAAACCTTTCAAGATTGGAGATGAAAACAACACTTGTGAAATTAGGTTGGGGTTGCAACATCTTTTAACTTCTCAGTTATTTGTAT

>68659_68659_6_PRKAR1A-NDFIP2_PRKAR1A_chr17_66511717_ENST00000589228_NDFIP2_chr13_80094945_ENST00000218652_length(amino acids)=312AA_BP=72
MRELGTPPPRTRSLAPAAARPQRTMESGSTAASEEARSLRECELYVQKHNIQALLKDSIVQLCTARPERPMAFLREYFERLEKLLNEEDN
SESSAIEQPPTSNPAPQIVQAASSAPALETDSSPPPYSSITVEVPTTSDTEVYGEFYPVPPPYSVATSLPTYDEAEKAKAAAMAAAAAET
SQRIQEEECPPRDDFSDADQLRVGNDGIFMLAFFMAFIFNWLGFCLSFCITNTIAGRYGAICGFGLSLIKWILIVRFSDYFTGYFNGQYW

--------------------------------------------------------------

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Fusion Gene PPI Analysis for PRKAR1A-NDFIP2


check button Go to ChiPPI (Chimeric Protein-Protein interactions) to see the chimeric PPI interaction in

ChiPPI page.


check button Protein-protein interactors with each fusion partner protein in wild-type (BIOGRID-3.4.160)
HgeneHgene's interactorsTgeneTgene's interactors


check button - Retained PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenStill interaction with


check button - Lost PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


check button - Retained PPIs, but lost function due to frame-shift fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


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Related Drugs for PRKAR1A-NDFIP2


check button Drugs targeting genes involved in this fusion gene.
(DrugBank Version 5.1.8 2021-05-08)
PartnerGeneUniProtAccDrugBank IDDrug nameDrug activityDrug typeDrug status

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Related Diseases for PRKAR1A-NDFIP2


check button Diseases associated with fusion partners.
(DisGeNet 4.0)
PartnerGeneDisease IDDisease name# pubmedsSource