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 | Fusion Gene Summary |
| Fusion Gene ORF analysis |
| Fusion Genomic Features |
| Fusion Protein Features |
| Fusion Gene Sequence |
| Fusion Gene PPI analysis |
| Related Drugs |
| Related Diseases |
Fusion gene:PRMT2-STX18 (FusionGDB2 ID:68925) |
Fusion Gene Summary for PRMT2-STX18 |
 Fusion gene summary |
| Fusion gene information | Fusion gene name: PRMT2-STX18 | Fusion gene ID: 68925 | Hgene | Tgene | Gene symbol | PRMT2 | STX18 | Gene ID | 3275 | 53407 |
| Gene name | protein arginine methyltransferase 2 | syntaxin 18 | |
| Synonyms | HRMT1L1 | Ufe1 | |
| Cytomap | 21q22.3 | 4p16.3-p16.2 | |
| Type of gene | protein-coding | protein-coding | |
| Description | protein arginine N-methyltransferase 2HMT1 (hnRNP methyltransferase, S. cerevisiae)-like 1HMT1 hnRNP methyltransferase-like 1PRMT2 alphaPRMT2 betaPRMT2 gammahistone-arginine N-methyltransferase PRMT2 | syntaxin-18cell growth-inhibiting gene 9 protein | |
| Modification date | 20200313 | 20200313 | |
| UniProtAcc | . | . | |
| Ensembl transtripts involved in fusion gene | ENST00000491389, ENST00000291705, ENST00000334494, ENST00000355680, ENST00000397628, ENST00000397637, ENST00000397638, ENST00000440086, ENST00000451211, ENST00000458387, | ENST00000306200, ENST00000505286, | |
| Fusion gene scores | * DoF score | 11 X 9 X 7=693 | 1 X 1 X 1=1 |
| # samples | 12 | 1 | |
| ** MAII score | log2(12/693*10)=-2.5298209465287 possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs). DoF>8 and MAII<0 | log2(1/1*10)=3.32192809488736 | |
| Context | PubMed: PRMT2 [Title/Abstract] AND STX18 [Title/Abstract] AND fusion [Title/Abstract] | ||
| Most frequent breakpoint | PRMT2(48068531)-STX18(4473433), # samples:3 | ||
| Anticipated loss of major functional domain due to fusion event. | |||
| * DoF score (Degree of Frequency) = # partners X # break points X # cancer types ** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10) |
| Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez |
| Partner | Gene | GO ID | GO term | PubMed ID |
| Hgene | PRMT2 | GO:0016571 | histone methylation | 19405910 |
| Hgene | PRMT2 | GO:0032088 | negative regulation of NF-kappaB transcription factor activity | 16648481 |
| Hgene | PRMT2 | GO:0045892 | negative regulation of transcription, DNA-templated | 16648481 |
| Hgene | PRMT2 | GO:0045893 | positive regulation of transcription, DNA-templated | 12039952 |
| Hgene | PRMT2 | GO:0060765 | regulation of androgen receptor signaling pathway | 17587566 |
| Fusion gene breakpoints across PRMT2 (5'-gene) * Click on the image to open the UCSC genome browser with custom track showing this image in a new window. |
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| Fusion gene breakpoints across STX18 (3'-gene) * Click on the image to open the UCSC genome browser with custom track showing this image in a new window. |
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| Fusion gene information from two resources (ChiTars 5.0 and ChimerDB 4.0) * All genome coordinats were lifted-over on hg19. * Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser. |
| Source | Disease | Sample | Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand |
| ChimerDB4 | LUAD | TCGA-93-A4JP-01A | PRMT2 | chr21 | 48068531 | - | STX18 | chr4 | 4473433 | - |
| ChimerDB4 | LUAD | TCGA-93-A4JP-01A | PRMT2 | chr21 | 48068531 | + | STX18 | chr4 | 4473433 | - |
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Fusion Gene ORF analysis for PRMT2-STX18 |
| Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure. * Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser. |
| ORF | Henst | Tenst | Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand |
| 3UTR-3CDS | ENST00000491389 | ENST00000306200 | PRMT2 | chr21 | 48068531 | + | STX18 | chr4 | 4473433 | - |
| 3UTR-3CDS | ENST00000491389 | ENST00000505286 | PRMT2 | chr21 | 48068531 | + | STX18 | chr4 | 4473433 | - |
| In-frame | ENST00000291705 | ENST00000306200 | PRMT2 | chr21 | 48068531 | + | STX18 | chr4 | 4473433 | - |
| In-frame | ENST00000291705 | ENST00000505286 | PRMT2 | chr21 | 48068531 | + | STX18 | chr4 | 4473433 | - |
| In-frame | ENST00000334494 | ENST00000306200 | PRMT2 | chr21 | 48068531 | + | STX18 | chr4 | 4473433 | - |
| In-frame | ENST00000334494 | ENST00000505286 | PRMT2 | chr21 | 48068531 | + | STX18 | chr4 | 4473433 | - |
| In-frame | ENST00000355680 | ENST00000306200 | PRMT2 | chr21 | 48068531 | + | STX18 | chr4 | 4473433 | - |
| In-frame | ENST00000355680 | ENST00000505286 | PRMT2 | chr21 | 48068531 | + | STX18 | chr4 | 4473433 | - |
| In-frame | ENST00000397628 | ENST00000306200 | PRMT2 | chr21 | 48068531 | + | STX18 | chr4 | 4473433 | - |
| In-frame | ENST00000397628 | ENST00000505286 | PRMT2 | chr21 | 48068531 | + | STX18 | chr4 | 4473433 | - |
| In-frame | ENST00000397637 | ENST00000306200 | PRMT2 | chr21 | 48068531 | + | STX18 | chr4 | 4473433 | - |
| In-frame | ENST00000397637 | ENST00000505286 | PRMT2 | chr21 | 48068531 | + | STX18 | chr4 | 4473433 | - |
| In-frame | ENST00000397638 | ENST00000306200 | PRMT2 | chr21 | 48068531 | + | STX18 | chr4 | 4473433 | - |
| In-frame | ENST00000397638 | ENST00000505286 | PRMT2 | chr21 | 48068531 | + | STX18 | chr4 | 4473433 | - |
| In-frame | ENST00000440086 | ENST00000306200 | PRMT2 | chr21 | 48068531 | + | STX18 | chr4 | 4473433 | - |
| In-frame | ENST00000440086 | ENST00000505286 | PRMT2 | chr21 | 48068531 | + | STX18 | chr4 | 4473433 | - |
| In-frame | ENST00000451211 | ENST00000306200 | PRMT2 | chr21 | 48068531 | + | STX18 | chr4 | 4473433 | - |
| In-frame | ENST00000451211 | ENST00000505286 | PRMT2 | chr21 | 48068531 | + | STX18 | chr4 | 4473433 | - |
| In-frame | ENST00000458387 | ENST00000306200 | PRMT2 | chr21 | 48068531 | + | STX18 | chr4 | 4473433 | - |
| In-frame | ENST00000458387 | ENST00000505286 | PRMT2 | chr21 | 48068531 | + | STX18 | chr4 | 4473433 | - |
| ORFfinder result based on the fusion transcript sequence of in-frame fusion genes. |
| Henst | Tenst | Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand | Seq length (transcript) | BP loci (transcript) | Predicted start (transcript) | Predicted stop (transcript) | Seq length (amino acids) |
| ENST00000355680 | PRMT2 | chr21 | 48068531 | + | ENST00000505286 | STX18 | chr4 | 4473433 | - | 2417 | 1251 | 762 | 2009 | 415 |
| ENST00000355680 | PRMT2 | chr21 | 48068531 | + | ENST00000306200 | STX18 | chr4 | 4473433 | - | 3157 | 1251 | 762 | 2090 | 442 |
| ENST00000397638 | PRMT2 | chr21 | 48068531 | + | ENST00000505286 | STX18 | chr4 | 4473433 | - | 1860 | 694 | 205 | 1452 | 415 |
| ENST00000397638 | PRMT2 | chr21 | 48068531 | + | ENST00000306200 | STX18 | chr4 | 4473433 | - | 2600 | 694 | 205 | 1533 | 442 |
| ENST00000291705 | PRMT2 | chr21 | 48068531 | + | ENST00000505286 | STX18 | chr4 | 4473433 | - | 1830 | 664 | 175 | 1422 | 415 |
| ENST00000291705 | PRMT2 | chr21 | 48068531 | + | ENST00000306200 | STX18 | chr4 | 4473433 | - | 2570 | 664 | 175 | 1503 | 442 |
| ENST00000458387 | PRMT2 | chr21 | 48068531 | + | ENST00000505286 | STX18 | chr4 | 4473433 | - | 1830 | 664 | 175 | 1422 | 415 |
| ENST00000458387 | PRMT2 | chr21 | 48068531 | + | ENST00000306200 | STX18 | chr4 | 4473433 | - | 2570 | 664 | 175 | 1503 | 442 |
| ENST00000451211 | PRMT2 | chr21 | 48068531 | + | ENST00000505286 | STX18 | chr4 | 4473433 | - | 1830 | 664 | 175 | 1422 | 415 |
| ENST00000451211 | PRMT2 | chr21 | 48068531 | + | ENST00000306200 | STX18 | chr4 | 4473433 | - | 2570 | 664 | 175 | 1503 | 442 |
| ENST00000397637 | PRMT2 | chr21 | 48068531 | + | ENST00000505286 | STX18 | chr4 | 4473433 | - | 2609 | 1443 | 954 | 2201 | 415 |
| ENST00000397637 | PRMT2 | chr21 | 48068531 | + | ENST00000306200 | STX18 | chr4 | 4473433 | - | 3349 | 1443 | 954 | 2282 | 442 |
| ENST00000334494 | PRMT2 | chr21 | 48068531 | + | ENST00000505286 | STX18 | chr4 | 4473433 | - | 1822 | 656 | 167 | 1414 | 415 |
| ENST00000334494 | PRMT2 | chr21 | 48068531 | + | ENST00000306200 | STX18 | chr4 | 4473433 | - | 2562 | 656 | 167 | 1495 | 442 |
| ENST00000397628 | PRMT2 | chr21 | 48068531 | + | ENST00000505286 | STX18 | chr4 | 4473433 | - | 1801 | 635 | 146 | 1393 | 415 |
| ENST00000397628 | PRMT2 | chr21 | 48068531 | + | ENST00000306200 | STX18 | chr4 | 4473433 | - | 2541 | 635 | 146 | 1474 | 442 |
| ENST00000440086 | PRMT2 | chr21 | 48068531 | + | ENST00000505286 | STX18 | chr4 | 4473433 | - | 1794 | 628 | 139 | 1386 | 415 |
| ENST00000440086 | PRMT2 | chr21 | 48068531 | + | ENST00000306200 | STX18 | chr4 | 4473433 | - | 2534 | 628 | 139 | 1467 | 442 |
| DeepORF prediction of the coding potential based on the fusion transcript sequence of in-frame fusion genes. DeepORF is a coding potential classifier based on convolutional neural network by comparing the real Ribo-seq data. If the no-coding score < 0.5 and coding score > 0.5, then the in-frame fusion transcript is predicted as being likely translated. |
| Henst | Tenst | Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand | No-coding score | Coding score |
| ENST00000355680 | ENST00000505286 | PRMT2 | chr21 | 48068531 | + | STX18 | chr4 | 4473433 | - | 0.010468888 | 0.98953116 |
| ENST00000355680 | ENST00000306200 | PRMT2 | chr21 | 48068531 | + | STX18 | chr4 | 4473433 | - | 0.004617201 | 0.9953827 |
| ENST00000397638 | ENST00000505286 | PRMT2 | chr21 | 48068531 | + | STX18 | chr4 | 4473433 | - | 0.016059972 | 0.98394 |
| ENST00000397638 | ENST00000306200 | PRMT2 | chr21 | 48068531 | + | STX18 | chr4 | 4473433 | - | 0.004521224 | 0.9954788 |
| ENST00000291705 | ENST00000505286 | PRMT2 | chr21 | 48068531 | + | STX18 | chr4 | 4473433 | - | 0.018770732 | 0.9812292 |
| ENST00000291705 | ENST00000306200 | PRMT2 | chr21 | 48068531 | + | STX18 | chr4 | 4473433 | - | 0.00466451 | 0.9953355 |
| ENST00000458387 | ENST00000505286 | PRMT2 | chr21 | 48068531 | + | STX18 | chr4 | 4473433 | - | 0.018770732 | 0.9812292 |
| ENST00000458387 | ENST00000306200 | PRMT2 | chr21 | 48068531 | + | STX18 | chr4 | 4473433 | - | 0.00466451 | 0.9953355 |
| ENST00000451211 | ENST00000505286 | PRMT2 | chr21 | 48068531 | + | STX18 | chr4 | 4473433 | - | 0.018770732 | 0.9812292 |
| ENST00000451211 | ENST00000306200 | PRMT2 | chr21 | 48068531 | + | STX18 | chr4 | 4473433 | - | 0.00466451 | 0.9953355 |
| ENST00000397637 | ENST00000505286 | PRMT2 | chr21 | 48068531 | + | STX18 | chr4 | 4473433 | - | 0.00877074 | 0.9912293 |
| ENST00000397637 | ENST00000306200 | PRMT2 | chr21 | 48068531 | + | STX18 | chr4 | 4473433 | - | 0.00401551 | 0.99598455 |
| ENST00000334494 | ENST00000505286 | PRMT2 | chr21 | 48068531 | + | STX18 | chr4 | 4473433 | - | 0.019325105 | 0.9806749 |
| ENST00000334494 | ENST00000306200 | PRMT2 | chr21 | 48068531 | + | STX18 | chr4 | 4473433 | - | 0.004654889 | 0.99534506 |
| ENST00000397628 | ENST00000505286 | PRMT2 | chr21 | 48068531 | + | STX18 | chr4 | 4473433 | - | 0.020337125 | 0.97966284 |
| ENST00000397628 | ENST00000306200 | PRMT2 | chr21 | 48068531 | + | STX18 | chr4 | 4473433 | - | 0.004715184 | 0.99528486 |
| ENST00000440086 | ENST00000505286 | PRMT2 | chr21 | 48068531 | + | STX18 | chr4 | 4473433 | - | 0.020923303 | 0.97907674 |
| ENST00000440086 | ENST00000306200 | PRMT2 | chr21 | 48068531 | + | STX18 | chr4 | 4473433 | - | 0.004829967 | 0.99517006 |
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Fusion Genomic Features for PRMT2-STX18 |
| FusionAI prediction of the potential fusion gene breakpoint based on the pre-mature RNA sequence context (+/- 5kb of individual partner genes, total 20kb length sequence). FusionAI is a fusion gene breakpoint classifier based on convolutional neural network by comparing the fusion positive and negative sequence context of ~ 20K fusion gene data. From here, we can have the relative potentency of the 20K genomic sequence how individual sequnce will be likely used as the gene fusion breakpoints. |
| Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand | 1-p | p (fusion gene breakpoint) |
| Distribution of 44 human genomic features loci across 20kb length fusion breakpoint regions. We integrated a total of 44 different types of human genomic feature loci information across five big categories including virus integration sites, repeats, structural variants, chromatin states, and gene expression regulation. More details are in help page. |
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| Distribution of 44 human genomic features loci across 20kb length fusion breakpoint regions that are ovelapped with the top 1% feature importance score regions. More details are in help page. |
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Fusion Protein Features for PRMT2-STX18 |
| Four levels of functional features of fusion genes Go to FGviewer search page for the most frequent breakpoint (https://ccsmweb.uth.edu/FGviewer/chr21:48068531/chr4:4473433) - FGviewer provides the online visualization of the retention search of the protein functional features across DNA, RNA, protein, and pathological levels. - How to search 1. Put your fusion gene symbol. 2. Press the tab key until there will be shown the breakpoint information filled. 4. Go down and press 'Search' tab twice. 4. Go down to have the hyperlink of the search result. 5. Click the hyperlink. 6. See the FGviewer result for your fusion gene. |
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| Main function of each fusion partner protein. (from UniProt) |
| Hgene | Tgene |
| . | . |
| FUNCTION: Transcriptional activator which is required for calcium-dependent dendritic growth and branching in cortical neurons. Recruits CREB-binding protein (CREBBP) to nuclear bodies. Component of the CREST-BRG1 complex, a multiprotein complex that regulates promoter activation by orchestrating a calcium-dependent release of a repressor complex and a recruitment of an activator complex. In resting neurons, transcription of the c-FOS promoter is inhibited by BRG1-dependent recruitment of a phospho-RB1-HDAC1 repressor complex. Upon calcium influx, RB1 is dephosphorylated by calcineurin, which leads to release of the repressor complex. At the same time, there is increased recruitment of CREBBP to the promoter by a CREST-dependent mechanism, which leads to transcriptional activation. The CREST-BRG1 complex also binds to the NR2B promoter, and activity-dependent induction of NR2B expression involves a release of HDAC1 and recruitment of CREBBP (By similarity). {ECO:0000250}. | FUNCTION: Transcriptional activator which is required for calcium-dependent dendritic growth and branching in cortical neurons. Recruits CREB-binding protein (CREBBP) to nuclear bodies. Component of the CREST-BRG1 complex, a multiprotein complex that regulates promoter activation by orchestrating a calcium-dependent release of a repressor complex and a recruitment of an activator complex. In resting neurons, transcription of the c-FOS promoter is inhibited by BRG1-dependent recruitment of a phospho-RB1-HDAC1 repressor complex. Upon calcium influx, RB1 is dephosphorylated by calcineurin, which leads to release of the repressor complex. At the same time, there is increased recruitment of CREBBP to the promoter by a CREST-dependent mechanism, which leads to transcriptional activation. The CREST-BRG1 complex also binds to the NR2B promoter, and activity-dependent induction of NR2B expression involves a release of HDAC1 and recruitment of CREBBP (By similarity). {ECO:0000250}. |
| Retention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at * Minus value of BPloci means that the break pointn is located before the CDS. |
| - In-frame and retained protein feature among the 13 regional features. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Protein feature | Protein feature note |
| Hgene | PRMT2 | chr21:48068531 | chr4:4473433 | ENST00000334494 | + | 5 | 7 | 30_89 | 163 | 285.0 | Domain | SH3 |
| Hgene | PRMT2 | chr21:48068531 | chr4:4473433 | ENST00000355680 | + | 6 | 12 | 30_89 | 163 | 434.0 | Domain | SH3 |
| Hgene | PRMT2 | chr21:48068531 | chr4:4473433 | ENST00000397637 | + | 5 | 11 | 30_89 | 163 | 434.0 | Domain | SH3 |
| Hgene | PRMT2 | chr21:48068531 | chr4:4473433 | ENST00000397638 | + | 5 | 11 | 30_89 | 163 | 434.0 | Domain | SH3 |
| Hgene | PRMT2 | chr21:48068531 | chr4:4473433 | ENST00000440086 | + | 5 | 9 | 30_89 | 163 | 332.0 | Domain | SH3 |
| Tgene | STX18 | chr21:48068531 | chr4:4473433 | ENST00000306200 | 0 | 11 | 243_305 | 56 | 336.0 | Domain | Note=t-SNARE coiled-coil homology | |
| Tgene | STX18 | chr21:48068531 | chr4:4473433 | ENST00000306200 | 0 | 11 | 331_335 | 56 | 336.0 | Topological domain | Vesicular | |
| Tgene | STX18 | chr21:48068531 | chr4:4473433 | ENST00000306200 | 0 | 11 | 310_330 | 56 | 336.0 | Transmembrane | Helical%3B Anchor for type IV membrane protein |
| - In-frame and not-retained protein feature among the 13 regional features. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Protein feature | Protein feature note |
| Hgene | PRMT2 | chr21:48068531 | chr4:4473433 | ENST00000334494 | + | 5 | 7 | 99_432 | 163 | 285.0 | Domain | SAM-dependent MTase PRMT-type |
| Hgene | PRMT2 | chr21:48068531 | chr4:4473433 | ENST00000355680 | + | 6 | 12 | 99_432 | 163 | 434.0 | Domain | SAM-dependent MTase PRMT-type |
| Hgene | PRMT2 | chr21:48068531 | chr4:4473433 | ENST00000397637 | + | 5 | 11 | 99_432 | 163 | 434.0 | Domain | SAM-dependent MTase PRMT-type |
| Hgene | PRMT2 | chr21:48068531 | chr4:4473433 | ENST00000397638 | + | 5 | 11 | 99_432 | 163 | 434.0 | Domain | SAM-dependent MTase PRMT-type |
| Hgene | PRMT2 | chr21:48068531 | chr4:4473433 | ENST00000440086 | + | 5 | 9 | 99_432 | 163 | 332.0 | Domain | SAM-dependent MTase PRMT-type |
| Tgene | STX18 | chr21:48068531 | chr4:4473433 | ENST00000306200 | 0 | 11 | 1_309 | 56 | 336.0 | Topological domain | Cytoplasmic |
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Fusion Gene Sequence for PRMT2-STX18 |
| For in-frame fusion transcripts, we provide the fusion transcript sequences and fusion amino acid sequences. To have fusion amino acid sequence, we ran ORFfinder and chose the longest ORF among the all predicted ones. |
| >68925_68925_1_PRMT2-STX18_PRMT2_chr21_48068531_ENST00000291705_STX18_chr4_4473433_ENST00000306200_length(transcript)=2570nt_BP=664nt GGCCTGCGTGCACTGCGCTTGCGCGGGTTGAGGGCGGTGGCTCAGGCTCCTGGAAAGGACCGTCCACCCCTCCGCGCTGGCGGTGTGGAC GCGGAACTCAGCGGAGAAACGCGATTGAGAAATGGAAAAGAAAATGAAATAAATCAGCAGTTATGAGGCAGAGCCTAAGAGAACTATGGC AACATCAGGTGACTGTCCCAGAAGTGAATCGCAGGGAGAAGAGCCTGCTGAGTGCAGTGAGGCCGGTCTCCTGCAGGAGGGAGTACAGCC AGAGGAGTTTGTGGCCATCGCGGACTACGCTGCCACCGATGAGACCCAGCTCAGTTTTTTGAGAGGAGAAAAAATTCTTATCCTGAGACA AACCACTGCAGATTGGTGGTGGGGTGAGCGTGCGGGCTGCTGTGGGTACATTCCGGCAAACCATGTGGGGAAGCACGTGGATGAGTACGA CCCCGAGGACACGTGGCAGGATGAAGAGTACTTCGGCAGCTATGGAACTCTGAAACTCCACTTGGAGATGTTGGCAGACCAGCCACGAAC AACTAAATACCACAGTGTCATCCTGCAGAATAAAGAATCCCTGACGGATAAAGTCATCCTGGACGTGGGCTGTGGGACTGGGATCATCAG TCTCTTCTGTGCACACTATGCGCGGCCTAGAGCGATTTCTCACATTGGCAAACTGAGAGATTTTCTTCTGGAACACAGGAAAGATTATAT TAATGCTTATAGCCATACCATGTCTGAATATGGGAGGATGACAGACACAGAACGAGACCAGATAGACCAGGATGCCCAGATATTCATGAG GACCTGTTCAGAAGCAATTCAGCAACTACGAACAGAAGCTCACAAGGAGATACATTCCCAGCAAGTGAAGGAGCACAGGACCGCTGTTTT GGATTTCATTGAAGATTACTTGAAAAGAGTATGTAAACTTTACTCAGAACAGAGAGCCATCCGAGTTAAAAGAGTGGTGGATAAGAAAAG ATTATCTAAGCTGGAACCAGAACCAAATACAAAGACAAGAGAATCCACATCTTCTGAGAAAGTTTCACAGAGTCCTTCAAAAGACTCTGA AGAAAACCCTGCCACTGAAGAACGTCCAGAAAAAATTTTGGCTGAAACACAACCTGAATTGGGAACGTGGGGAGATGGCAAAGGCGAAGA TGAGTTATCCCCAGAAGAAATACAAATGTTTGAACAGGAAAATCAGCGACTAATTGGTGAAATGAACAGCTTGTTTGATGAAGTGAGGCA AATCGAAGGGAGAGTGGTTGAGATTTCCAGACTCCAAGAGATATTCACGGAAAAGGTTTTGCAACAGGAAGCTGAGATTGACAGCATTCA CCAGTTAGTTGTGGGGGCAACTGAAAATATCAAGGAAGGCAACGAAGACATAAGAGAGGCCATTAAAAACAACGCTGGCTTCCGCGTGTG GATCCTCTTCTTCCTCGTGATGTGCTCCTTCTCCTTGCTCTTCCTCGACTGGTACGACAGCTAGCCAGGGCCACGGGGGCCCAGCACGAG AGTCCTCATGGGCACTCACAGACTGCGTGCTTTCATGTACTTCCAGTGCTGGAGCATGGTATGACCAGATTTTATCACAGTGCCATTTGA AGGGAAAGGAGTTCAGACAGACAGACGTATTCCCCAAAAAGGGATACCCCAGGCCGATGGTGTTCAGCCATTTAGCAGCTGAAAAAGGAA ACAGTGCACACCAATGGGAGGCAGCCTGCGTAGCCCTCATCAGGCAAGACAGACTGAATGCAGGAGTGGGTGATTAGCTGCTCCTTGAAC TTGAGGCTGCCTTGGCAGCAGGGGCACAGCAGGCCTCAAGAGCCCCTAATTGTCTCAGGGTTCAAAGGAAGACACTGACCTTTCCCATCC CGGTAGCTTCAGGGAAGATCATAGTTAATAACGTCTCTCAACAAATGATTACTTCTTTGTTTCCTTGTGGCTTCTTGTCTGTCTGAGTCA ACGAATACACAGACTTACTGGATTATAGAAGAGAAAATTCACATCTGCCTTGTTAATCTAATAAATATAATTACAGCCCCTTAATGTGTT GTCAATGAGTCTAAGTTGACAAATTCAGTGGCAGCCCAGCCACCTCCTATCAATCAATCAGGGAAGAAATGCAGGGGAGACTGGGGCCCT CAGTGAGGGGCTGCCTGGCATTACTCCTCCAAAGACTGCTGCCCCCAGAACAGGCAGGGGGTGTGGGAGGGCCAGTTTCCCGCCACTGGG TCCAAGGAGCCTTTGTTCAAAGGAAGAAGTGGGCCACGGAAGAACGGGCCTGCTTCTCTCGTGCCTGTGCTTCTGACCTCCAGGAACTGT AAACAGGAACACCTATGTGTAACTGAAGGCATGAGACATCTGTACAGGAAGCATCCCAGCGCCCACATGGGCATGAGACAGTCTGCACTG CGCCTGGTGAAATGCGTGTGTGTACAGACAGTCCACTGGGCAGCACAGGTATCCTCATGTTCTTTATTTGCACAGAGTGAAATGTCAGAA >68925_68925_1_PRMT2-STX18_PRMT2_chr21_48068531_ENST00000291705_STX18_chr4_4473433_ENST00000306200_length(amino acids)=442AA_BP=163 MATSGDCPRSESQGEEPAECSEAGLLQEGVQPEEFVAIADYAATDETQLSFLRGEKILILRQTTADWWWGERAGCCGYIPANHVGKHVDE YDPEDTWQDEEYFGSYGTLKLHLEMLADQPRTTKYHSVILQNKESLTDKVILDVGCGTGIISLFCAHYARPRAISHIGKLRDFLLEHRKD YINAYSHTMSEYGRMTDTERDQIDQDAQIFMRTCSEAIQQLRTEAHKEIHSQQVKEHRTAVLDFIEDYLKRVCKLYSEQRAIRVKRVVDK KRLSKLEPEPNTKTRESTSSEKVSQSPSKDSEENPATEERPEKILAETQPELGTWGDGKGEDELSPEEIQMFEQENQRLIGEMNSLFDEV -------------------------------------------------------------- >68925_68925_2_PRMT2-STX18_PRMT2_chr21_48068531_ENST00000291705_STX18_chr4_4473433_ENST00000505286_length(transcript)=1830nt_BP=664nt GGCCTGCGTGCACTGCGCTTGCGCGGGTTGAGGGCGGTGGCTCAGGCTCCTGGAAAGGACCGTCCACCCCTCCGCGCTGGCGGTGTGGAC GCGGAACTCAGCGGAGAAACGCGATTGAGAAATGGAAAAGAAAATGAAATAAATCAGCAGTTATGAGGCAGAGCCTAAGAGAACTATGGC AACATCAGGTGACTGTCCCAGAAGTGAATCGCAGGGAGAAGAGCCTGCTGAGTGCAGTGAGGCCGGTCTCCTGCAGGAGGGAGTACAGCC AGAGGAGTTTGTGGCCATCGCGGACTACGCTGCCACCGATGAGACCCAGCTCAGTTTTTTGAGAGGAGAAAAAATTCTTATCCTGAGACA AACCACTGCAGATTGGTGGTGGGGTGAGCGTGCGGGCTGCTGTGGGTACATTCCGGCAAACCATGTGGGGAAGCACGTGGATGAGTACGA CCCCGAGGACACGTGGCAGGATGAAGAGTACTTCGGCAGCTATGGAACTCTGAAACTCCACTTGGAGATGTTGGCAGACCAGCCACGAAC AACTAAATACCACAGTGTCATCCTGCAGAATAAAGAATCCCTGACGGATAAAGTCATCCTGGACGTGGGCTGTGGGACTGGGATCATCAG TCTCTTCTGTGCACACTATGCGCGGCCTAGAGCGATTTCTCACATTGGCAAACTGAGAGATTTTCTTCTGGAACACAGGAAAGATTATAT TAATGCTTATAGCCATACCATGTCTGAATATGGGAGGATGACAGACACAGAACGAGACCAGATAGACCAGGATGCCCAGATATTCATGAG GACCTGTTCAGAAGCAATTCAGCAACTACGAACAGAAGCTCACAAGGAGATACATTCCCAGCAAGTGAAGGAGCACAGGACCGCTGTTTT GGATTTCATTGAAGATTACTTGAAAAGAGTATGTAAACTTTACTCAGAACAGAGAGCCATCCGAGTTAAAAGAGTGGTGGATAAGAAAAG ATTATCTAAGCTGGAACCAGAACCAAATACAAAGACAAGAGAATCCACATCTTCTGAGAAAGTTTCACAGAGTCCTTCAAAAGACTCTGA AGAAAACCCTGCCACTGAAGAACGTCCAGAAAAAATTTTGGCTGAAACACAACCTGAATTGGGAACGTGGGGAGATGGCAAAGGCGAAGA TGAGTTATCCCCAGAAGAAATACAAATGTTTGAACAGGAAAATCAGCGACTAATTGGTGAAATGAACAGCTTGTTTGATGAAGTGAGGCA AATCGAAGGGAGAGTGGTTGAGATTTCCAGACTCCAAGAGATATTCACGGAAAAGGTTTTGCAACAGGAAGCTGAGATTGACAGCATTCA CCAGTTAGTTGTGGGGGCAACTGAAAATATCAAGGAAGGCAACGAAGACATAAGAGAGGTCCCTCACCTATAAAATGCGGCCAATGAGTC ACACCACCGTGTTGCTGAGGACTCAAGTCAATGCACAGTGGCTCAAGTAAAGAAGCCAGGATGTGCCCCAGGTCACAGTGTGGACAGAAA AGAAAGCCAAAAGACACCACTGAAGTACAGCCCTTTTATCAACAGCGTCTTGATCTCAGTCCCACCAGGACGTCGGGAAGCACCTGACAC GCTACAGAACAAACAGCCCATTCAGACCAGCAGCGCGTGCATCAGGAAGGAGGCTCTGCAGGCCAGACAAACTCCCCTCCAGCCTCACCG CCACGCCCCTTCACGCTGTCCTCTCCATCTGCTGCTCGTCATCCCTCAGGGAAACGGACCAAGGGTTCCCCTCTTCCCTCCCACCTCGGC >68925_68925_2_PRMT2-STX18_PRMT2_chr21_48068531_ENST00000291705_STX18_chr4_4473433_ENST00000505286_length(amino acids)=415AA_BP=163 MATSGDCPRSESQGEEPAECSEAGLLQEGVQPEEFVAIADYAATDETQLSFLRGEKILILRQTTADWWWGERAGCCGYIPANHVGKHVDE YDPEDTWQDEEYFGSYGTLKLHLEMLADQPRTTKYHSVILQNKESLTDKVILDVGCGTGIISLFCAHYARPRAISHIGKLRDFLLEHRKD YINAYSHTMSEYGRMTDTERDQIDQDAQIFMRTCSEAIQQLRTEAHKEIHSQQVKEHRTAVLDFIEDYLKRVCKLYSEQRAIRVKRVVDK KRLSKLEPEPNTKTRESTSSEKVSQSPSKDSEENPATEERPEKILAETQPELGTWGDGKGEDELSPEEIQMFEQENQRLIGEMNSLFDEV -------------------------------------------------------------- >68925_68925_3_PRMT2-STX18_PRMT2_chr21_48068531_ENST00000334494_STX18_chr4_4473433_ENST00000306200_length(transcript)=2562nt_BP=656nt TGCACTGCGCTTGCGCGGGTTGAGGGCGGTGGCTCAGGCTCCTGGAAAGGACCGTCCACCCCTCCGCGCTGGCGGTGTGGACGCGGAACT CAGCGGAGAAACGCGATTGAGAAATGGAAAAGAAAATGAAATAAATCAGCAGTTATGAGGCAGAGCCTAAGAGAACTATGGCAACATCAG GTGACTGTCCCAGAAGTGAATCGCAGGGAGAAGAGCCTGCTGAGTGCAGTGAGGCCGGTCTCCTGCAGGAGGGAGTACAGCCAGAGGAGT TTGTGGCCATCGCGGACTACGCTGCCACCGATGAGACCCAGCTCAGTTTTTTGAGAGGAGAAAAAATTCTTATCCTGAGACAAACCACTG CAGATTGGTGGTGGGGTGAGCGTGCGGGCTGCTGTGGGTACATTCCGGCAAACCATGTGGGGAAGCACGTGGATGAGTACGACCCCGAGG ACACGTGGCAGGATGAAGAGTACTTCGGCAGCTATGGAACTCTGAAACTCCACTTGGAGATGTTGGCAGACCAGCCACGAACAACTAAAT ACCACAGTGTCATCCTGCAGAATAAAGAATCCCTGACGGATAAAGTCATCCTGGACGTGGGCTGTGGGACTGGGATCATCAGTCTCTTCT GTGCACACTATGCGCGGCCTAGAGCGATTTCTCACATTGGCAAACTGAGAGATTTTCTTCTGGAACACAGGAAAGATTATATTAATGCTT ATAGCCATACCATGTCTGAATATGGGAGGATGACAGACACAGAACGAGACCAGATAGACCAGGATGCCCAGATATTCATGAGGACCTGTT CAGAAGCAATTCAGCAACTACGAACAGAAGCTCACAAGGAGATACATTCCCAGCAAGTGAAGGAGCACAGGACCGCTGTTTTGGATTTCA TTGAAGATTACTTGAAAAGAGTATGTAAACTTTACTCAGAACAGAGAGCCATCCGAGTTAAAAGAGTGGTGGATAAGAAAAGATTATCTA AGCTGGAACCAGAACCAAATACAAAGACAAGAGAATCCACATCTTCTGAGAAAGTTTCACAGAGTCCTTCAAAAGACTCTGAAGAAAACC CTGCCACTGAAGAACGTCCAGAAAAAATTTTGGCTGAAACACAACCTGAATTGGGAACGTGGGGAGATGGCAAAGGCGAAGATGAGTTAT CCCCAGAAGAAATACAAATGTTTGAACAGGAAAATCAGCGACTAATTGGTGAAATGAACAGCTTGTTTGATGAAGTGAGGCAAATCGAAG GGAGAGTGGTTGAGATTTCCAGACTCCAAGAGATATTCACGGAAAAGGTTTTGCAACAGGAAGCTGAGATTGACAGCATTCACCAGTTAG TTGTGGGGGCAACTGAAAATATCAAGGAAGGCAACGAAGACATAAGAGAGGCCATTAAAAACAACGCTGGCTTCCGCGTGTGGATCCTCT TCTTCCTCGTGATGTGCTCCTTCTCCTTGCTCTTCCTCGACTGGTACGACAGCTAGCCAGGGCCACGGGGGCCCAGCACGAGAGTCCTCA TGGGCACTCACAGACTGCGTGCTTTCATGTACTTCCAGTGCTGGAGCATGGTATGACCAGATTTTATCACAGTGCCATTTGAAGGGAAAG GAGTTCAGACAGACAGACGTATTCCCCAAAAAGGGATACCCCAGGCCGATGGTGTTCAGCCATTTAGCAGCTGAAAAAGGAAACAGTGCA CACCAATGGGAGGCAGCCTGCGTAGCCCTCATCAGGCAAGACAGACTGAATGCAGGAGTGGGTGATTAGCTGCTCCTTGAACTTGAGGCT GCCTTGGCAGCAGGGGCACAGCAGGCCTCAAGAGCCCCTAATTGTCTCAGGGTTCAAAGGAAGACACTGACCTTTCCCATCCCGGTAGCT TCAGGGAAGATCATAGTTAATAACGTCTCTCAACAAATGATTACTTCTTTGTTTCCTTGTGGCTTCTTGTCTGTCTGAGTCAACGAATAC ACAGACTTACTGGATTATAGAAGAGAAAATTCACATCTGCCTTGTTAATCTAATAAATATAATTACAGCCCCTTAATGTGTTGTCAATGA GTCTAAGTTGACAAATTCAGTGGCAGCCCAGCCACCTCCTATCAATCAATCAGGGAAGAAATGCAGGGGAGACTGGGGCCCTCAGTGAGG GGCTGCCTGGCATTACTCCTCCAAAGACTGCTGCCCCCAGAACAGGCAGGGGGTGTGGGAGGGCCAGTTTCCCGCCACTGGGTCCAAGGA GCCTTTGTTCAAAGGAAGAAGTGGGCCACGGAAGAACGGGCCTGCTTCTCTCGTGCCTGTGCTTCTGACCTCCAGGAACTGTAAACAGGA ACACCTATGTGTAACTGAAGGCATGAGACATCTGTACAGGAAGCATCCCAGCGCCCACATGGGCATGAGACAGTCTGCACTGCGCCTGGT GAAATGCGTGTGTGTACAGACAGTCCACTGGGCAGCACAGGTATCCTCATGTTCTTTATTTGCACAGAGTGAAATGTCAGAAGTTACATG >68925_68925_3_PRMT2-STX18_PRMT2_chr21_48068531_ENST00000334494_STX18_chr4_4473433_ENST00000306200_length(amino acids)=442AA_BP=163 MATSGDCPRSESQGEEPAECSEAGLLQEGVQPEEFVAIADYAATDETQLSFLRGEKILILRQTTADWWWGERAGCCGYIPANHVGKHVDE YDPEDTWQDEEYFGSYGTLKLHLEMLADQPRTTKYHSVILQNKESLTDKVILDVGCGTGIISLFCAHYARPRAISHIGKLRDFLLEHRKD YINAYSHTMSEYGRMTDTERDQIDQDAQIFMRTCSEAIQQLRTEAHKEIHSQQVKEHRTAVLDFIEDYLKRVCKLYSEQRAIRVKRVVDK KRLSKLEPEPNTKTRESTSSEKVSQSPSKDSEENPATEERPEKILAETQPELGTWGDGKGEDELSPEEIQMFEQENQRLIGEMNSLFDEV -------------------------------------------------------------- >68925_68925_4_PRMT2-STX18_PRMT2_chr21_48068531_ENST00000334494_STX18_chr4_4473433_ENST00000505286_length(transcript)=1822nt_BP=656nt TGCACTGCGCTTGCGCGGGTTGAGGGCGGTGGCTCAGGCTCCTGGAAAGGACCGTCCACCCCTCCGCGCTGGCGGTGTGGACGCGGAACT CAGCGGAGAAACGCGATTGAGAAATGGAAAAGAAAATGAAATAAATCAGCAGTTATGAGGCAGAGCCTAAGAGAACTATGGCAACATCAG GTGACTGTCCCAGAAGTGAATCGCAGGGAGAAGAGCCTGCTGAGTGCAGTGAGGCCGGTCTCCTGCAGGAGGGAGTACAGCCAGAGGAGT TTGTGGCCATCGCGGACTACGCTGCCACCGATGAGACCCAGCTCAGTTTTTTGAGAGGAGAAAAAATTCTTATCCTGAGACAAACCACTG CAGATTGGTGGTGGGGTGAGCGTGCGGGCTGCTGTGGGTACATTCCGGCAAACCATGTGGGGAAGCACGTGGATGAGTACGACCCCGAGG ACACGTGGCAGGATGAAGAGTACTTCGGCAGCTATGGAACTCTGAAACTCCACTTGGAGATGTTGGCAGACCAGCCACGAACAACTAAAT ACCACAGTGTCATCCTGCAGAATAAAGAATCCCTGACGGATAAAGTCATCCTGGACGTGGGCTGTGGGACTGGGATCATCAGTCTCTTCT GTGCACACTATGCGCGGCCTAGAGCGATTTCTCACATTGGCAAACTGAGAGATTTTCTTCTGGAACACAGGAAAGATTATATTAATGCTT ATAGCCATACCATGTCTGAATATGGGAGGATGACAGACACAGAACGAGACCAGATAGACCAGGATGCCCAGATATTCATGAGGACCTGTT CAGAAGCAATTCAGCAACTACGAACAGAAGCTCACAAGGAGATACATTCCCAGCAAGTGAAGGAGCACAGGACCGCTGTTTTGGATTTCA TTGAAGATTACTTGAAAAGAGTATGTAAACTTTACTCAGAACAGAGAGCCATCCGAGTTAAAAGAGTGGTGGATAAGAAAAGATTATCTA AGCTGGAACCAGAACCAAATACAAAGACAAGAGAATCCACATCTTCTGAGAAAGTTTCACAGAGTCCTTCAAAAGACTCTGAAGAAAACC CTGCCACTGAAGAACGTCCAGAAAAAATTTTGGCTGAAACACAACCTGAATTGGGAACGTGGGGAGATGGCAAAGGCGAAGATGAGTTAT CCCCAGAAGAAATACAAATGTTTGAACAGGAAAATCAGCGACTAATTGGTGAAATGAACAGCTTGTTTGATGAAGTGAGGCAAATCGAAG GGAGAGTGGTTGAGATTTCCAGACTCCAAGAGATATTCACGGAAAAGGTTTTGCAACAGGAAGCTGAGATTGACAGCATTCACCAGTTAG TTGTGGGGGCAACTGAAAATATCAAGGAAGGCAACGAAGACATAAGAGAGGTCCCTCACCTATAAAATGCGGCCAATGAGTCACACCACC GTGTTGCTGAGGACTCAAGTCAATGCACAGTGGCTCAAGTAAAGAAGCCAGGATGTGCCCCAGGTCACAGTGTGGACAGAAAAGAAAGCC AAAAGACACCACTGAAGTACAGCCCTTTTATCAACAGCGTCTTGATCTCAGTCCCACCAGGACGTCGGGAAGCACCTGACACGCTACAGA ACAAACAGCCCATTCAGACCAGCAGCGCGTGCATCAGGAAGGAGGCTCTGCAGGCCAGACAAACTCCCCTCCAGCCTCACCGCCACGCCC CTTCACGCTGTCCTCTCCATCTGCTGCTCGTCATCCCTCAGGGAAACGGACCAAGGGTTCCCCTCTTCCCTCCCACCTCGGCACCCAGCA >68925_68925_4_PRMT2-STX18_PRMT2_chr21_48068531_ENST00000334494_STX18_chr4_4473433_ENST00000505286_length(amino acids)=415AA_BP=163 MATSGDCPRSESQGEEPAECSEAGLLQEGVQPEEFVAIADYAATDETQLSFLRGEKILILRQTTADWWWGERAGCCGYIPANHVGKHVDE YDPEDTWQDEEYFGSYGTLKLHLEMLADQPRTTKYHSVILQNKESLTDKVILDVGCGTGIISLFCAHYARPRAISHIGKLRDFLLEHRKD YINAYSHTMSEYGRMTDTERDQIDQDAQIFMRTCSEAIQQLRTEAHKEIHSQQVKEHRTAVLDFIEDYLKRVCKLYSEQRAIRVKRVVDK KRLSKLEPEPNTKTRESTSSEKVSQSPSKDSEENPATEERPEKILAETQPELGTWGDGKGEDELSPEEIQMFEQENQRLIGEMNSLFDEV -------------------------------------------------------------- >68925_68925_5_PRMT2-STX18_PRMT2_chr21_48068531_ENST00000355680_STX18_chr4_4473433_ENST00000306200_length(transcript)=3157nt_BP=1251nt ACTTATCCAGAAGAAAGGCAGAGGGCGCACACTGCGCAGCGCGGATGGGAAAGTTAACTGAATTATTTGCGGGAAGACAGAGGAGGTGGG GGGTCCCCCAAGCCCCAGCCATTTTGTGGCTCGTAGGGGTTGTCGCTTCCCAAGCCGTGAATGGCCCAAACCCGCCCCCCGCCCCAGGTC GGACTCCTGCCCCGCGCCCCTCTGGGTCGGACCCCAAGCCGAGCCCCCCAACCCCGCGGCTGGGCTGGGCGATTGGGGACGAGCTCCACA CATGGAGAACCTGGCCTCGCCTCGCAAGACCGCGGGACGCGCAGATGTGAAGTGCGCCTGCGCGGGGCGCAGCCCCAGCTGCAGACGATC TGTGAGCGACGCGCCGGCGCAAGTCGAGGGCGGTGGCTTGGCTTCCCTGGAATGGGGGACGTCTTAGGACTGCGCCTGCGCGGGGCGCCG GGCCCTGGGCGGGGCCTTCCCGGCTGACGGCCTGCGTGCACTGCGCTTGCGCGGGTTGAGGGCGGTGGCTCAGGCTCCTGGAAAGGACCG TCCACCCCTCCGCGCTGGCGGTGTGGACGCGGAACTCAGCGGAGAAACGCGATTGAGAGCAGTGTGTGGATTACACTATCACTGGAAAAA TACGAATTGAGAAGAAGGAAAAGACTGGAAGATGCAGACCTTGGTTCCTGTTAGTGGAAACACTGTAAGGTCCCAGAAATGGAAAAGAAA ATGAAATAAATCAGCAGTTATGAGGCAGAGCCTAAGAGAACTATGGCAACATCAGGTGACTGTCCCAGAAGTGAATCGCAGGGAGAAGAG CCTGCTGAGTGCAGTGAGGCCGGTCTCCTGCAGGAGGGAGTACAGCCAGAGGAGTTTGTGGCCATCGCGGACTACGCTGCCACCGATGAG ACCCAGCTCAGTTTTTTGAGAGGAGAAAAAATTCTTATCCTGAGACAAACCACTGCAGATTGGTGGTGGGGTGAGCGTGCGGGCTGCTGT GGGTACATTCCGGCAAACCATGTGGGGAAGCACGTGGATGAGTACGACCCCGAGGACACGTGGCAGGATGAAGAGTACTTCGGCAGCTAT GGAACTCTGAAACTCCACTTGGAGATGTTGGCAGACCAGCCACGAACAACTAAATACCACAGTGTCATCCTGCAGAATAAAGAATCCCTG ACGGATAAAGTCATCCTGGACGTGGGCTGTGGGACTGGGATCATCAGTCTCTTCTGTGCACACTATGCGCGGCCTAGAGCGATTTCTCAC ATTGGCAAACTGAGAGATTTTCTTCTGGAACACAGGAAAGATTATATTAATGCTTATAGCCATACCATGTCTGAATATGGGAGGATGACA GACACAGAACGAGACCAGATAGACCAGGATGCCCAGATATTCATGAGGACCTGTTCAGAAGCAATTCAGCAACTACGAACAGAAGCTCAC AAGGAGATACATTCCCAGCAAGTGAAGGAGCACAGGACCGCTGTTTTGGATTTCATTGAAGATTACTTGAAAAGAGTATGTAAACTTTAC TCAGAACAGAGAGCCATCCGAGTTAAAAGAGTGGTGGATAAGAAAAGATTATCTAAGCTGGAACCAGAACCAAATACAAAGACAAGAGAA TCCACATCTTCTGAGAAAGTTTCACAGAGTCCTTCAAAAGACTCTGAAGAAAACCCTGCCACTGAAGAACGTCCAGAAAAAATTTTGGCT GAAACACAACCTGAATTGGGAACGTGGGGAGATGGCAAAGGCGAAGATGAGTTATCCCCAGAAGAAATACAAATGTTTGAACAGGAAAAT CAGCGACTAATTGGTGAAATGAACAGCTTGTTTGATGAAGTGAGGCAAATCGAAGGGAGAGTGGTTGAGATTTCCAGACTCCAAGAGATA TTCACGGAAAAGGTTTTGCAACAGGAAGCTGAGATTGACAGCATTCACCAGTTAGTTGTGGGGGCAACTGAAAATATCAAGGAAGGCAAC GAAGACATAAGAGAGGCCATTAAAAACAACGCTGGCTTCCGCGTGTGGATCCTCTTCTTCCTCGTGATGTGCTCCTTCTCCTTGCTCTTC CTCGACTGGTACGACAGCTAGCCAGGGCCACGGGGGCCCAGCACGAGAGTCCTCATGGGCACTCACAGACTGCGTGCTTTCATGTACTTC CAGTGCTGGAGCATGGTATGACCAGATTTTATCACAGTGCCATTTGAAGGGAAAGGAGTTCAGACAGACAGACGTATTCCCCAAAAAGGG ATACCCCAGGCCGATGGTGTTCAGCCATTTAGCAGCTGAAAAAGGAAACAGTGCACACCAATGGGAGGCAGCCTGCGTAGCCCTCATCAG GCAAGACAGACTGAATGCAGGAGTGGGTGATTAGCTGCTCCTTGAACTTGAGGCTGCCTTGGCAGCAGGGGCACAGCAGGCCTCAAGAGC CCCTAATTGTCTCAGGGTTCAAAGGAAGACACTGACCTTTCCCATCCCGGTAGCTTCAGGGAAGATCATAGTTAATAACGTCTCTCAACA AATGATTACTTCTTTGTTTCCTTGTGGCTTCTTGTCTGTCTGAGTCAACGAATACACAGACTTACTGGATTATAGAAGAGAAAATTCACA TCTGCCTTGTTAATCTAATAAATATAATTACAGCCCCTTAATGTGTTGTCAATGAGTCTAAGTTGACAAATTCAGTGGCAGCCCAGCCAC CTCCTATCAATCAATCAGGGAAGAAATGCAGGGGAGACTGGGGCCCTCAGTGAGGGGCTGCCTGGCATTACTCCTCCAAAGACTGCTGCC CCCAGAACAGGCAGGGGGTGTGGGAGGGCCAGTTTCCCGCCACTGGGTCCAAGGAGCCTTTGTTCAAAGGAAGAAGTGGGCCACGGAAGA ACGGGCCTGCTTCTCTCGTGCCTGTGCTTCTGACCTCCAGGAACTGTAAACAGGAACACCTATGTGTAACTGAAGGCATGAGACATCTGT ACAGGAAGCATCCCAGCGCCCACATGGGCATGAGACAGTCTGCACTGCGCCTGGTGAAATGCGTGTGTGTACAGACAGTCCACTGGGCAG CACAGGTATCCTCATGTTCTTTATTTGCACAGAGTGAAATGTCAGAAGTTACATGTAAATGAATTCACAGTCAATAAAGTCCACGTCTAC >68925_68925_5_PRMT2-STX18_PRMT2_chr21_48068531_ENST00000355680_STX18_chr4_4473433_ENST00000306200_length(amino acids)=442AA_BP=163 MATSGDCPRSESQGEEPAECSEAGLLQEGVQPEEFVAIADYAATDETQLSFLRGEKILILRQTTADWWWGERAGCCGYIPANHVGKHVDE YDPEDTWQDEEYFGSYGTLKLHLEMLADQPRTTKYHSVILQNKESLTDKVILDVGCGTGIISLFCAHYARPRAISHIGKLRDFLLEHRKD YINAYSHTMSEYGRMTDTERDQIDQDAQIFMRTCSEAIQQLRTEAHKEIHSQQVKEHRTAVLDFIEDYLKRVCKLYSEQRAIRVKRVVDK KRLSKLEPEPNTKTRESTSSEKVSQSPSKDSEENPATEERPEKILAETQPELGTWGDGKGEDELSPEEIQMFEQENQRLIGEMNSLFDEV -------------------------------------------------------------- >68925_68925_6_PRMT2-STX18_PRMT2_chr21_48068531_ENST00000355680_STX18_chr4_4473433_ENST00000505286_length(transcript)=2417nt_BP=1251nt ACTTATCCAGAAGAAAGGCAGAGGGCGCACACTGCGCAGCGCGGATGGGAAAGTTAACTGAATTATTTGCGGGAAGACAGAGGAGGTGGG GGGTCCCCCAAGCCCCAGCCATTTTGTGGCTCGTAGGGGTTGTCGCTTCCCAAGCCGTGAATGGCCCAAACCCGCCCCCCGCCCCAGGTC GGACTCCTGCCCCGCGCCCCTCTGGGTCGGACCCCAAGCCGAGCCCCCCAACCCCGCGGCTGGGCTGGGCGATTGGGGACGAGCTCCACA CATGGAGAACCTGGCCTCGCCTCGCAAGACCGCGGGACGCGCAGATGTGAAGTGCGCCTGCGCGGGGCGCAGCCCCAGCTGCAGACGATC TGTGAGCGACGCGCCGGCGCAAGTCGAGGGCGGTGGCTTGGCTTCCCTGGAATGGGGGACGTCTTAGGACTGCGCCTGCGCGGGGCGCCG GGCCCTGGGCGGGGCCTTCCCGGCTGACGGCCTGCGTGCACTGCGCTTGCGCGGGTTGAGGGCGGTGGCTCAGGCTCCTGGAAAGGACCG TCCACCCCTCCGCGCTGGCGGTGTGGACGCGGAACTCAGCGGAGAAACGCGATTGAGAGCAGTGTGTGGATTACACTATCACTGGAAAAA TACGAATTGAGAAGAAGGAAAAGACTGGAAGATGCAGACCTTGGTTCCTGTTAGTGGAAACACTGTAAGGTCCCAGAAATGGAAAAGAAA ATGAAATAAATCAGCAGTTATGAGGCAGAGCCTAAGAGAACTATGGCAACATCAGGTGACTGTCCCAGAAGTGAATCGCAGGGAGAAGAG CCTGCTGAGTGCAGTGAGGCCGGTCTCCTGCAGGAGGGAGTACAGCCAGAGGAGTTTGTGGCCATCGCGGACTACGCTGCCACCGATGAG ACCCAGCTCAGTTTTTTGAGAGGAGAAAAAATTCTTATCCTGAGACAAACCACTGCAGATTGGTGGTGGGGTGAGCGTGCGGGCTGCTGT GGGTACATTCCGGCAAACCATGTGGGGAAGCACGTGGATGAGTACGACCCCGAGGACACGTGGCAGGATGAAGAGTACTTCGGCAGCTAT GGAACTCTGAAACTCCACTTGGAGATGTTGGCAGACCAGCCACGAACAACTAAATACCACAGTGTCATCCTGCAGAATAAAGAATCCCTG ACGGATAAAGTCATCCTGGACGTGGGCTGTGGGACTGGGATCATCAGTCTCTTCTGTGCACACTATGCGCGGCCTAGAGCGATTTCTCAC ATTGGCAAACTGAGAGATTTTCTTCTGGAACACAGGAAAGATTATATTAATGCTTATAGCCATACCATGTCTGAATATGGGAGGATGACA GACACAGAACGAGACCAGATAGACCAGGATGCCCAGATATTCATGAGGACCTGTTCAGAAGCAATTCAGCAACTACGAACAGAAGCTCAC AAGGAGATACATTCCCAGCAAGTGAAGGAGCACAGGACCGCTGTTTTGGATTTCATTGAAGATTACTTGAAAAGAGTATGTAAACTTTAC TCAGAACAGAGAGCCATCCGAGTTAAAAGAGTGGTGGATAAGAAAAGATTATCTAAGCTGGAACCAGAACCAAATACAAAGACAAGAGAA TCCACATCTTCTGAGAAAGTTTCACAGAGTCCTTCAAAAGACTCTGAAGAAAACCCTGCCACTGAAGAACGTCCAGAAAAAATTTTGGCT GAAACACAACCTGAATTGGGAACGTGGGGAGATGGCAAAGGCGAAGATGAGTTATCCCCAGAAGAAATACAAATGTTTGAACAGGAAAAT CAGCGACTAATTGGTGAAATGAACAGCTTGTTTGATGAAGTGAGGCAAATCGAAGGGAGAGTGGTTGAGATTTCCAGACTCCAAGAGATA TTCACGGAAAAGGTTTTGCAACAGGAAGCTGAGATTGACAGCATTCACCAGTTAGTTGTGGGGGCAACTGAAAATATCAAGGAAGGCAAC GAAGACATAAGAGAGGTCCCTCACCTATAAAATGCGGCCAATGAGTCACACCACCGTGTTGCTGAGGACTCAAGTCAATGCACAGTGGCT CAAGTAAAGAAGCCAGGATGTGCCCCAGGTCACAGTGTGGACAGAAAAGAAAGCCAAAAGACACCACTGAAGTACAGCCCTTTTATCAAC AGCGTCTTGATCTCAGTCCCACCAGGACGTCGGGAAGCACCTGACACGCTACAGAACAAACAGCCCATTCAGACCAGCAGCGCGTGCATC AGGAAGGAGGCTCTGCAGGCCAGACAAACTCCCCTCCAGCCTCACCGCCACGCCCCTTCACGCTGTCCTCTCCATCTGCTGCTCGTCATC >68925_68925_6_PRMT2-STX18_PRMT2_chr21_48068531_ENST00000355680_STX18_chr4_4473433_ENST00000505286_length(amino acids)=415AA_BP=163 MATSGDCPRSESQGEEPAECSEAGLLQEGVQPEEFVAIADYAATDETQLSFLRGEKILILRQTTADWWWGERAGCCGYIPANHVGKHVDE YDPEDTWQDEEYFGSYGTLKLHLEMLADQPRTTKYHSVILQNKESLTDKVILDVGCGTGIISLFCAHYARPRAISHIGKLRDFLLEHRKD YINAYSHTMSEYGRMTDTERDQIDQDAQIFMRTCSEAIQQLRTEAHKEIHSQQVKEHRTAVLDFIEDYLKRVCKLYSEQRAIRVKRVVDK KRLSKLEPEPNTKTRESTSSEKVSQSPSKDSEENPATEERPEKILAETQPELGTWGDGKGEDELSPEEIQMFEQENQRLIGEMNSLFDEV -------------------------------------------------------------- >68925_68925_7_PRMT2-STX18_PRMT2_chr21_48068531_ENST00000397628_STX18_chr4_4473433_ENST00000306200_length(transcript)=2541nt_BP=635nt GAGGGCGGTGGCTCAGGCTCCTGGAAAGGACCGTCCACCCCTCCGCGCTGGCGGTGTGGACGCGGAACTCAGCGGAGAAACGCGATTGAG AAATGGAAAAGAAAATGAAATAAATCAGCAGTTATGAGGCAGAGCCTAAGAGAACTATGGCAACATCAGGTGACTGTCCCAGAAGTGAAT CGCAGGGAGAAGAGCCTGCTGAGTGCAGTGAGGCCGGTCTCCTGCAGGAGGGAGTACAGCCAGAGGAGTTTGTGGCCATCGCGGACTACG CTGCCACCGATGAGACCCAGCTCAGTTTTTTGAGAGGAGAAAAAATTCTTATCCTGAGACAAACCACTGCAGATTGGTGGTGGGGTGAGC GTGCGGGCTGCTGTGGGTACATTCCGGCAAACCATGTGGGGAAGCACGTGGATGAGTACGACCCCGAGGACACGTGGCAGGATGAAGAGT ACTTCGGCAGCTATGGAACTCTGAAACTCCACTTGGAGATGTTGGCAGACCAGCCACGAACAACTAAATACCACAGTGTCATCCTGCAGA ATAAAGAATCCCTGACGGATAAAGTCATCCTGGACGTGGGCTGTGGGACTGGGATCATCAGTCTCTTCTGTGCACACTATGCGCGGCCTA GAGCGATTTCTCACATTGGCAAACTGAGAGATTTTCTTCTGGAACACAGGAAAGATTATATTAATGCTTATAGCCATACCATGTCTGAAT ATGGGAGGATGACAGACACAGAACGAGACCAGATAGACCAGGATGCCCAGATATTCATGAGGACCTGTTCAGAAGCAATTCAGCAACTAC GAACAGAAGCTCACAAGGAGATACATTCCCAGCAAGTGAAGGAGCACAGGACCGCTGTTTTGGATTTCATTGAAGATTACTTGAAAAGAG TATGTAAACTTTACTCAGAACAGAGAGCCATCCGAGTTAAAAGAGTGGTGGATAAGAAAAGATTATCTAAGCTGGAACCAGAACCAAATA CAAAGACAAGAGAATCCACATCTTCTGAGAAAGTTTCACAGAGTCCTTCAAAAGACTCTGAAGAAAACCCTGCCACTGAAGAACGTCCAG AAAAAATTTTGGCTGAAACACAACCTGAATTGGGAACGTGGGGAGATGGCAAAGGCGAAGATGAGTTATCCCCAGAAGAAATACAAATGT TTGAACAGGAAAATCAGCGACTAATTGGTGAAATGAACAGCTTGTTTGATGAAGTGAGGCAAATCGAAGGGAGAGTGGTTGAGATTTCCA GACTCCAAGAGATATTCACGGAAAAGGTTTTGCAACAGGAAGCTGAGATTGACAGCATTCACCAGTTAGTTGTGGGGGCAACTGAAAATA TCAAGGAAGGCAACGAAGACATAAGAGAGGCCATTAAAAACAACGCTGGCTTCCGCGTGTGGATCCTCTTCTTCCTCGTGATGTGCTCCT TCTCCTTGCTCTTCCTCGACTGGTACGACAGCTAGCCAGGGCCACGGGGGCCCAGCACGAGAGTCCTCATGGGCACTCACAGACTGCGTG CTTTCATGTACTTCCAGTGCTGGAGCATGGTATGACCAGATTTTATCACAGTGCCATTTGAAGGGAAAGGAGTTCAGACAGACAGACGTA TTCCCCAAAAAGGGATACCCCAGGCCGATGGTGTTCAGCCATTTAGCAGCTGAAAAAGGAAACAGTGCACACCAATGGGAGGCAGCCTGC GTAGCCCTCATCAGGCAAGACAGACTGAATGCAGGAGTGGGTGATTAGCTGCTCCTTGAACTTGAGGCTGCCTTGGCAGCAGGGGCACAG CAGGCCTCAAGAGCCCCTAATTGTCTCAGGGTTCAAAGGAAGACACTGACCTTTCCCATCCCGGTAGCTTCAGGGAAGATCATAGTTAAT AACGTCTCTCAACAAATGATTACTTCTTTGTTTCCTTGTGGCTTCTTGTCTGTCTGAGTCAACGAATACACAGACTTACTGGATTATAGA AGAGAAAATTCACATCTGCCTTGTTAATCTAATAAATATAATTACAGCCCCTTAATGTGTTGTCAATGAGTCTAAGTTGACAAATTCAGT GGCAGCCCAGCCACCTCCTATCAATCAATCAGGGAAGAAATGCAGGGGAGACTGGGGCCCTCAGTGAGGGGCTGCCTGGCATTACTCCTC CAAAGACTGCTGCCCCCAGAACAGGCAGGGGGTGTGGGAGGGCCAGTTTCCCGCCACTGGGTCCAAGGAGCCTTTGTTCAAAGGAAGAAG TGGGCCACGGAAGAACGGGCCTGCTTCTCTCGTGCCTGTGCTTCTGACCTCCAGGAACTGTAAACAGGAACACCTATGTGTAACTGAAGG CATGAGACATCTGTACAGGAAGCATCCCAGCGCCCACATGGGCATGAGACAGTCTGCACTGCGCCTGGTGAAATGCGTGTGTGTACAGAC AGTCCACTGGGCAGCACAGGTATCCTCATGTTCTTTATTTGCACAGAGTGAAATGTCAGAAGTTACATGTAAATGAATTCACAGTCAATA >68925_68925_7_PRMT2-STX18_PRMT2_chr21_48068531_ENST00000397628_STX18_chr4_4473433_ENST00000306200_length(amino acids)=442AA_BP=163 MATSGDCPRSESQGEEPAECSEAGLLQEGVQPEEFVAIADYAATDETQLSFLRGEKILILRQTTADWWWGERAGCCGYIPANHVGKHVDE YDPEDTWQDEEYFGSYGTLKLHLEMLADQPRTTKYHSVILQNKESLTDKVILDVGCGTGIISLFCAHYARPRAISHIGKLRDFLLEHRKD YINAYSHTMSEYGRMTDTERDQIDQDAQIFMRTCSEAIQQLRTEAHKEIHSQQVKEHRTAVLDFIEDYLKRVCKLYSEQRAIRVKRVVDK KRLSKLEPEPNTKTRESTSSEKVSQSPSKDSEENPATEERPEKILAETQPELGTWGDGKGEDELSPEEIQMFEQENQRLIGEMNSLFDEV -------------------------------------------------------------- >68925_68925_8_PRMT2-STX18_PRMT2_chr21_48068531_ENST00000397628_STX18_chr4_4473433_ENST00000505286_length(transcript)=1801nt_BP=635nt GAGGGCGGTGGCTCAGGCTCCTGGAAAGGACCGTCCACCCCTCCGCGCTGGCGGTGTGGACGCGGAACTCAGCGGAGAAACGCGATTGAG AAATGGAAAAGAAAATGAAATAAATCAGCAGTTATGAGGCAGAGCCTAAGAGAACTATGGCAACATCAGGTGACTGTCCCAGAAGTGAAT CGCAGGGAGAAGAGCCTGCTGAGTGCAGTGAGGCCGGTCTCCTGCAGGAGGGAGTACAGCCAGAGGAGTTTGTGGCCATCGCGGACTACG CTGCCACCGATGAGACCCAGCTCAGTTTTTTGAGAGGAGAAAAAATTCTTATCCTGAGACAAACCACTGCAGATTGGTGGTGGGGTGAGC GTGCGGGCTGCTGTGGGTACATTCCGGCAAACCATGTGGGGAAGCACGTGGATGAGTACGACCCCGAGGACACGTGGCAGGATGAAGAGT ACTTCGGCAGCTATGGAACTCTGAAACTCCACTTGGAGATGTTGGCAGACCAGCCACGAACAACTAAATACCACAGTGTCATCCTGCAGA ATAAAGAATCCCTGACGGATAAAGTCATCCTGGACGTGGGCTGTGGGACTGGGATCATCAGTCTCTTCTGTGCACACTATGCGCGGCCTA GAGCGATTTCTCACATTGGCAAACTGAGAGATTTTCTTCTGGAACACAGGAAAGATTATATTAATGCTTATAGCCATACCATGTCTGAAT ATGGGAGGATGACAGACACAGAACGAGACCAGATAGACCAGGATGCCCAGATATTCATGAGGACCTGTTCAGAAGCAATTCAGCAACTAC GAACAGAAGCTCACAAGGAGATACATTCCCAGCAAGTGAAGGAGCACAGGACCGCTGTTTTGGATTTCATTGAAGATTACTTGAAAAGAG TATGTAAACTTTACTCAGAACAGAGAGCCATCCGAGTTAAAAGAGTGGTGGATAAGAAAAGATTATCTAAGCTGGAACCAGAACCAAATA CAAAGACAAGAGAATCCACATCTTCTGAGAAAGTTTCACAGAGTCCTTCAAAAGACTCTGAAGAAAACCCTGCCACTGAAGAACGTCCAG AAAAAATTTTGGCTGAAACACAACCTGAATTGGGAACGTGGGGAGATGGCAAAGGCGAAGATGAGTTATCCCCAGAAGAAATACAAATGT TTGAACAGGAAAATCAGCGACTAATTGGTGAAATGAACAGCTTGTTTGATGAAGTGAGGCAAATCGAAGGGAGAGTGGTTGAGATTTCCA GACTCCAAGAGATATTCACGGAAAAGGTTTTGCAACAGGAAGCTGAGATTGACAGCATTCACCAGTTAGTTGTGGGGGCAACTGAAAATA TCAAGGAAGGCAACGAAGACATAAGAGAGGTCCCTCACCTATAAAATGCGGCCAATGAGTCACACCACCGTGTTGCTGAGGACTCAAGTC AATGCACAGTGGCTCAAGTAAAGAAGCCAGGATGTGCCCCAGGTCACAGTGTGGACAGAAAAGAAAGCCAAAAGACACCACTGAAGTACA GCCCTTTTATCAACAGCGTCTTGATCTCAGTCCCACCAGGACGTCGGGAAGCACCTGACACGCTACAGAACAAACAGCCCATTCAGACCA GCAGCGCGTGCATCAGGAAGGAGGCTCTGCAGGCCAGACAAACTCCCCTCCAGCCTCACCGCCACGCCCCTTCACGCTGTCCTCTCCATC TGCTGCTCGTCATCCCTCAGGGAAACGGACCAAGGGTTCCCCTCTTCCCTCCCACCTCGGCACCCAGCAGAGTCCTGCAAGACCTGATGC >68925_68925_8_PRMT2-STX18_PRMT2_chr21_48068531_ENST00000397628_STX18_chr4_4473433_ENST00000505286_length(amino acids)=415AA_BP=163 MATSGDCPRSESQGEEPAECSEAGLLQEGVQPEEFVAIADYAATDETQLSFLRGEKILILRQTTADWWWGERAGCCGYIPANHVGKHVDE YDPEDTWQDEEYFGSYGTLKLHLEMLADQPRTTKYHSVILQNKESLTDKVILDVGCGTGIISLFCAHYARPRAISHIGKLRDFLLEHRKD YINAYSHTMSEYGRMTDTERDQIDQDAQIFMRTCSEAIQQLRTEAHKEIHSQQVKEHRTAVLDFIEDYLKRVCKLYSEQRAIRVKRVVDK KRLSKLEPEPNTKTRESTSSEKVSQSPSKDSEENPATEERPEKILAETQPELGTWGDGKGEDELSPEEIQMFEQENQRLIGEMNSLFDEV -------------------------------------------------------------- >68925_68925_9_PRMT2-STX18_PRMT2_chr21_48068531_ENST00000397637_STX18_chr4_4473433_ENST00000306200_length(transcript)=3349nt_BP=1443nt GCGTGCACTGCGCTTGCGCGGGTTGAGGGCGGTGGCTCAGGCTCCTGGAAAGGACCGTCCACCCCTCCGCGCTGGCGGTGTGGACGCGGA ACTCAGCGGAGAAACGCGATTGAGGTAGGTGTCCTGATGGGCAGCTCAGATGGCTGGACTGCACGTAAGGAAGGACAGGCCAGGTGAGGC GTCCTCGCACTGCGTGTGCGTCGCTGGCGGACAGAGGCCTCCGCCCCCTTTTGGGACCTCCGAGCGCCTTCGCGATCTCAGCCACTTTCC CTGGCGTCCAAACGGGAGCTCGGTCCCCGTCACACCCTTCCCTGCGTGCCGCACCCCTTCCCGGCCACTCCCGCCGTCCAGCGCCTTCTA CGGCCACGCCCACCCCACCACCATCTCTGTCACGCCCTTCGCGGCCACGCCCACCTGCCTGGCGGCCCCTGCCCCGAAGCTCGCGGCGCT GTCCCAGCCTGACCCTCTCGTGCCCCTGCGTCCACGCGTGGCCCTCTCGCTTCCTGCCCCCTTCTCACCCCCCTTCACTGGCCACCTGTT CCAACCCTCCATGATCCTGTTCCTCCCGAGGGCATCTTAGGAGGGCAGGGTCCTGCGCGCACTGCGGCCTCCACTCCGACCCCGTCCCAG TTTGGACCCAGGTCTTCCAATGAAAATATAATTATGCAAATCAGTAAGCATTTGTAACTACGAATATCACAAAAATAAGCTTCAAGTCTG GATTTAGAAGTGAAGCATGCATTTTAAACAAAGAATTGCTATGCAATTTTAAAAACACATTGATCCCAGAGCAGTGTGTGGATTACACTA TCACTGGAAAAATACGAATTGAGAAGAAGGAAAAGACTGGAAGATGCAGACCTTGGTTCCTGTTAGTGGAAACACTGTAAGGTCCCAGAA ATGGAAAAGAAAATGAAATAAATCAGCAGTTATGAGGCAGAGCCTAAGAGAACTATGGCAACATCAGGTGACTGTCCCAGAAGTGAATCG CAGGGAGAAGAGCCTGCTGAGTGCAGTGAGGCCGGTCTCCTGCAGGAGGGAGTACAGCCAGAGGAGTTTGTGGCCATCGCGGACTACGCT GCCACCGATGAGACCCAGCTCAGTTTTTTGAGAGGAGAAAAAATTCTTATCCTGAGACAAACCACTGCAGATTGGTGGTGGGGTGAGCGT GCGGGCTGCTGTGGGTACATTCCGGCAAACCATGTGGGGAAGCACGTGGATGAGTACGACCCCGAGGACACGTGGCAGGATGAAGAGTAC TTCGGCAGCTATGGAACTCTGAAACTCCACTTGGAGATGTTGGCAGACCAGCCACGAACAACTAAATACCACAGTGTCATCCTGCAGAAT AAAGAATCCCTGACGGATAAAGTCATCCTGGACGTGGGCTGTGGGACTGGGATCATCAGTCTCTTCTGTGCACACTATGCGCGGCCTAGA GCGATTTCTCACATTGGCAAACTGAGAGATTTTCTTCTGGAACACAGGAAAGATTATATTAATGCTTATAGCCATACCATGTCTGAATAT GGGAGGATGACAGACACAGAACGAGACCAGATAGACCAGGATGCCCAGATATTCATGAGGACCTGTTCAGAAGCAATTCAGCAACTACGA ACAGAAGCTCACAAGGAGATACATTCCCAGCAAGTGAAGGAGCACAGGACCGCTGTTTTGGATTTCATTGAAGATTACTTGAAAAGAGTA TGTAAACTTTACTCAGAACAGAGAGCCATCCGAGTTAAAAGAGTGGTGGATAAGAAAAGATTATCTAAGCTGGAACCAGAACCAAATACA AAGACAAGAGAATCCACATCTTCTGAGAAAGTTTCACAGAGTCCTTCAAAAGACTCTGAAGAAAACCCTGCCACTGAAGAACGTCCAGAA AAAATTTTGGCTGAAACACAACCTGAATTGGGAACGTGGGGAGATGGCAAAGGCGAAGATGAGTTATCCCCAGAAGAAATACAAATGTTT GAACAGGAAAATCAGCGACTAATTGGTGAAATGAACAGCTTGTTTGATGAAGTGAGGCAAATCGAAGGGAGAGTGGTTGAGATTTCCAGA CTCCAAGAGATATTCACGGAAAAGGTTTTGCAACAGGAAGCTGAGATTGACAGCATTCACCAGTTAGTTGTGGGGGCAACTGAAAATATC AAGGAAGGCAACGAAGACATAAGAGAGGCCATTAAAAACAACGCTGGCTTCCGCGTGTGGATCCTCTTCTTCCTCGTGATGTGCTCCTTC TCCTTGCTCTTCCTCGACTGGTACGACAGCTAGCCAGGGCCACGGGGGCCCAGCACGAGAGTCCTCATGGGCACTCACAGACTGCGTGCT TTCATGTACTTCCAGTGCTGGAGCATGGTATGACCAGATTTTATCACAGTGCCATTTGAAGGGAAAGGAGTTCAGACAGACAGACGTATT CCCCAAAAAGGGATACCCCAGGCCGATGGTGTTCAGCCATTTAGCAGCTGAAAAAGGAAACAGTGCACACCAATGGGAGGCAGCCTGCGT AGCCCTCATCAGGCAAGACAGACTGAATGCAGGAGTGGGTGATTAGCTGCTCCTTGAACTTGAGGCTGCCTTGGCAGCAGGGGCACAGCA GGCCTCAAGAGCCCCTAATTGTCTCAGGGTTCAAAGGAAGACACTGACCTTTCCCATCCCGGTAGCTTCAGGGAAGATCATAGTTAATAA CGTCTCTCAACAAATGATTACTTCTTTGTTTCCTTGTGGCTTCTTGTCTGTCTGAGTCAACGAATACACAGACTTACTGGATTATAGAAG AGAAAATTCACATCTGCCTTGTTAATCTAATAAATATAATTACAGCCCCTTAATGTGTTGTCAATGAGTCTAAGTTGACAAATTCAGTGG CAGCCCAGCCACCTCCTATCAATCAATCAGGGAAGAAATGCAGGGGAGACTGGGGCCCTCAGTGAGGGGCTGCCTGGCATTACTCCTCCA AAGACTGCTGCCCCCAGAACAGGCAGGGGGTGTGGGAGGGCCAGTTTCCCGCCACTGGGTCCAAGGAGCCTTTGTTCAAAGGAAGAAGTG GGCCACGGAAGAACGGGCCTGCTTCTCTCGTGCCTGTGCTTCTGACCTCCAGGAACTGTAAACAGGAACACCTATGTGTAACTGAAGGCA TGAGACATCTGTACAGGAAGCATCCCAGCGCCCACATGGGCATGAGACAGTCTGCACTGCGCCTGGTGAAATGCGTGTGTGTACAGACAG TCCACTGGGCAGCACAGGTATCCTCATGTTCTTTATTTGCACAGAGTGAAATGTCAGAAGTTACATGTAAATGAATTCACAGTCAATAAA >68925_68925_9_PRMT2-STX18_PRMT2_chr21_48068531_ENST00000397637_STX18_chr4_4473433_ENST00000306200_length(amino acids)=442AA_BP=163 MATSGDCPRSESQGEEPAECSEAGLLQEGVQPEEFVAIADYAATDETQLSFLRGEKILILRQTTADWWWGERAGCCGYIPANHVGKHVDE YDPEDTWQDEEYFGSYGTLKLHLEMLADQPRTTKYHSVILQNKESLTDKVILDVGCGTGIISLFCAHYARPRAISHIGKLRDFLLEHRKD YINAYSHTMSEYGRMTDTERDQIDQDAQIFMRTCSEAIQQLRTEAHKEIHSQQVKEHRTAVLDFIEDYLKRVCKLYSEQRAIRVKRVVDK KRLSKLEPEPNTKTRESTSSEKVSQSPSKDSEENPATEERPEKILAETQPELGTWGDGKGEDELSPEEIQMFEQENQRLIGEMNSLFDEV -------------------------------------------------------------- >68925_68925_10_PRMT2-STX18_PRMT2_chr21_48068531_ENST00000397637_STX18_chr4_4473433_ENST00000505286_length(transcript)=2609nt_BP=1443nt GCGTGCACTGCGCTTGCGCGGGTTGAGGGCGGTGGCTCAGGCTCCTGGAAAGGACCGTCCACCCCTCCGCGCTGGCGGTGTGGACGCGGA ACTCAGCGGAGAAACGCGATTGAGGTAGGTGTCCTGATGGGCAGCTCAGATGGCTGGACTGCACGTAAGGAAGGACAGGCCAGGTGAGGC GTCCTCGCACTGCGTGTGCGTCGCTGGCGGACAGAGGCCTCCGCCCCCTTTTGGGACCTCCGAGCGCCTTCGCGATCTCAGCCACTTTCC CTGGCGTCCAAACGGGAGCTCGGTCCCCGTCACACCCTTCCCTGCGTGCCGCACCCCTTCCCGGCCACTCCCGCCGTCCAGCGCCTTCTA CGGCCACGCCCACCCCACCACCATCTCTGTCACGCCCTTCGCGGCCACGCCCACCTGCCTGGCGGCCCCTGCCCCGAAGCTCGCGGCGCT GTCCCAGCCTGACCCTCTCGTGCCCCTGCGTCCACGCGTGGCCCTCTCGCTTCCTGCCCCCTTCTCACCCCCCTTCACTGGCCACCTGTT CCAACCCTCCATGATCCTGTTCCTCCCGAGGGCATCTTAGGAGGGCAGGGTCCTGCGCGCACTGCGGCCTCCACTCCGACCCCGTCCCAG TTTGGACCCAGGTCTTCCAATGAAAATATAATTATGCAAATCAGTAAGCATTTGTAACTACGAATATCACAAAAATAAGCTTCAAGTCTG GATTTAGAAGTGAAGCATGCATTTTAAACAAAGAATTGCTATGCAATTTTAAAAACACATTGATCCCAGAGCAGTGTGTGGATTACACTA TCACTGGAAAAATACGAATTGAGAAGAAGGAAAAGACTGGAAGATGCAGACCTTGGTTCCTGTTAGTGGAAACACTGTAAGGTCCCAGAA ATGGAAAAGAAAATGAAATAAATCAGCAGTTATGAGGCAGAGCCTAAGAGAACTATGGCAACATCAGGTGACTGTCCCAGAAGTGAATCG CAGGGAGAAGAGCCTGCTGAGTGCAGTGAGGCCGGTCTCCTGCAGGAGGGAGTACAGCCAGAGGAGTTTGTGGCCATCGCGGACTACGCT GCCACCGATGAGACCCAGCTCAGTTTTTTGAGAGGAGAAAAAATTCTTATCCTGAGACAAACCACTGCAGATTGGTGGTGGGGTGAGCGT GCGGGCTGCTGTGGGTACATTCCGGCAAACCATGTGGGGAAGCACGTGGATGAGTACGACCCCGAGGACACGTGGCAGGATGAAGAGTAC TTCGGCAGCTATGGAACTCTGAAACTCCACTTGGAGATGTTGGCAGACCAGCCACGAACAACTAAATACCACAGTGTCATCCTGCAGAAT AAAGAATCCCTGACGGATAAAGTCATCCTGGACGTGGGCTGTGGGACTGGGATCATCAGTCTCTTCTGTGCACACTATGCGCGGCCTAGA GCGATTTCTCACATTGGCAAACTGAGAGATTTTCTTCTGGAACACAGGAAAGATTATATTAATGCTTATAGCCATACCATGTCTGAATAT GGGAGGATGACAGACACAGAACGAGACCAGATAGACCAGGATGCCCAGATATTCATGAGGACCTGTTCAGAAGCAATTCAGCAACTACGA ACAGAAGCTCACAAGGAGATACATTCCCAGCAAGTGAAGGAGCACAGGACCGCTGTTTTGGATTTCATTGAAGATTACTTGAAAAGAGTA TGTAAACTTTACTCAGAACAGAGAGCCATCCGAGTTAAAAGAGTGGTGGATAAGAAAAGATTATCTAAGCTGGAACCAGAACCAAATACA AAGACAAGAGAATCCACATCTTCTGAGAAAGTTTCACAGAGTCCTTCAAAAGACTCTGAAGAAAACCCTGCCACTGAAGAACGTCCAGAA AAAATTTTGGCTGAAACACAACCTGAATTGGGAACGTGGGGAGATGGCAAAGGCGAAGATGAGTTATCCCCAGAAGAAATACAAATGTTT GAACAGGAAAATCAGCGACTAATTGGTGAAATGAACAGCTTGTTTGATGAAGTGAGGCAAATCGAAGGGAGAGTGGTTGAGATTTCCAGA CTCCAAGAGATATTCACGGAAAAGGTTTTGCAACAGGAAGCTGAGATTGACAGCATTCACCAGTTAGTTGTGGGGGCAACTGAAAATATC AAGGAAGGCAACGAAGACATAAGAGAGGTCCCTCACCTATAAAATGCGGCCAATGAGTCACACCACCGTGTTGCTGAGGACTCAAGTCAA TGCACAGTGGCTCAAGTAAAGAAGCCAGGATGTGCCCCAGGTCACAGTGTGGACAGAAAAGAAAGCCAAAAGACACCACTGAAGTACAGC CCTTTTATCAACAGCGTCTTGATCTCAGTCCCACCAGGACGTCGGGAAGCACCTGACACGCTACAGAACAAACAGCCCATTCAGACCAGC AGCGCGTGCATCAGGAAGGAGGCTCTGCAGGCCAGACAAACTCCCCTCCAGCCTCACCGCCACGCCCCTTCACGCTGTCCTCTCCATCTG >68925_68925_10_PRMT2-STX18_PRMT2_chr21_48068531_ENST00000397637_STX18_chr4_4473433_ENST00000505286_length(amino acids)=415AA_BP=163 MATSGDCPRSESQGEEPAECSEAGLLQEGVQPEEFVAIADYAATDETQLSFLRGEKILILRQTTADWWWGERAGCCGYIPANHVGKHVDE YDPEDTWQDEEYFGSYGTLKLHLEMLADQPRTTKYHSVILQNKESLTDKVILDVGCGTGIISLFCAHYARPRAISHIGKLRDFLLEHRKD YINAYSHTMSEYGRMTDTERDQIDQDAQIFMRTCSEAIQQLRTEAHKEIHSQQVKEHRTAVLDFIEDYLKRVCKLYSEQRAIRVKRVVDK KRLSKLEPEPNTKTRESTSSEKVSQSPSKDSEENPATEERPEKILAETQPELGTWGDGKGEDELSPEEIQMFEQENQRLIGEMNSLFDEV -------------------------------------------------------------- >68925_68925_11_PRMT2-STX18_PRMT2_chr21_48068531_ENST00000397638_STX18_chr4_4473433_ENST00000306200_length(transcript)=2600nt_BP=694nt CGGGCCCTGGGCGGGGCCTTCCCGGCTGACGGCCTGCGTGCACTGCGCTTGCGCGGGTTGAGGGCGGTGGCTCAGGCTCCTGGAAAGGAC CGTCCACCCCTCCGCGCTGGCGGTGTGGACGCGGAACTCAGCGGAGAAACGCGATTGAGAAATGGAAAAGAAAATGAAATAAATCAGCAG TTATGAGGCAGAGCCTAAGAGAACTATGGCAACATCAGGTGACTGTCCCAGAAGTGAATCGCAGGGAGAAGAGCCTGCTGAGTGCAGTGA GGCCGGTCTCCTGCAGGAGGGAGTACAGCCAGAGGAGTTTGTGGCCATCGCGGACTACGCTGCCACCGATGAGACCCAGCTCAGTTTTTT GAGAGGAGAAAAAATTCTTATCCTGAGACAAACCACTGCAGATTGGTGGTGGGGTGAGCGTGCGGGCTGCTGTGGGTACATTCCGGCAAA CCATGTGGGGAAGCACGTGGATGAGTACGACCCCGAGGACACGTGGCAGGATGAAGAGTACTTCGGCAGCTATGGAACTCTGAAACTCCA CTTGGAGATGTTGGCAGACCAGCCACGAACAACTAAATACCACAGTGTCATCCTGCAGAATAAAGAATCCCTGACGGATAAAGTCATCCT GGACGTGGGCTGTGGGACTGGGATCATCAGTCTCTTCTGTGCACACTATGCGCGGCCTAGAGCGATTTCTCACATTGGCAAACTGAGAGA TTTTCTTCTGGAACACAGGAAAGATTATATTAATGCTTATAGCCATACCATGTCTGAATATGGGAGGATGACAGACACAGAACGAGACCA GATAGACCAGGATGCCCAGATATTCATGAGGACCTGTTCAGAAGCAATTCAGCAACTACGAACAGAAGCTCACAAGGAGATACATTCCCA GCAAGTGAAGGAGCACAGGACCGCTGTTTTGGATTTCATTGAAGATTACTTGAAAAGAGTATGTAAACTTTACTCAGAACAGAGAGCCAT CCGAGTTAAAAGAGTGGTGGATAAGAAAAGATTATCTAAGCTGGAACCAGAACCAAATACAAAGACAAGAGAATCCACATCTTCTGAGAA AGTTTCACAGAGTCCTTCAAAAGACTCTGAAGAAAACCCTGCCACTGAAGAACGTCCAGAAAAAATTTTGGCTGAAACACAACCTGAATT GGGAACGTGGGGAGATGGCAAAGGCGAAGATGAGTTATCCCCAGAAGAAATACAAATGTTTGAACAGGAAAATCAGCGACTAATTGGTGA AATGAACAGCTTGTTTGATGAAGTGAGGCAAATCGAAGGGAGAGTGGTTGAGATTTCCAGACTCCAAGAGATATTCACGGAAAAGGTTTT GCAACAGGAAGCTGAGATTGACAGCATTCACCAGTTAGTTGTGGGGGCAACTGAAAATATCAAGGAAGGCAACGAAGACATAAGAGAGGC CATTAAAAACAACGCTGGCTTCCGCGTGTGGATCCTCTTCTTCCTCGTGATGTGCTCCTTCTCCTTGCTCTTCCTCGACTGGTACGACAG CTAGCCAGGGCCACGGGGGCCCAGCACGAGAGTCCTCATGGGCACTCACAGACTGCGTGCTTTCATGTACTTCCAGTGCTGGAGCATGGT ATGACCAGATTTTATCACAGTGCCATTTGAAGGGAAAGGAGTTCAGACAGACAGACGTATTCCCCAAAAAGGGATACCCCAGGCCGATGG TGTTCAGCCATTTAGCAGCTGAAAAAGGAAACAGTGCACACCAATGGGAGGCAGCCTGCGTAGCCCTCATCAGGCAAGACAGACTGAATG CAGGAGTGGGTGATTAGCTGCTCCTTGAACTTGAGGCTGCCTTGGCAGCAGGGGCACAGCAGGCCTCAAGAGCCCCTAATTGTCTCAGGG TTCAAAGGAAGACACTGACCTTTCCCATCCCGGTAGCTTCAGGGAAGATCATAGTTAATAACGTCTCTCAACAAATGATTACTTCTTTGT TTCCTTGTGGCTTCTTGTCTGTCTGAGTCAACGAATACACAGACTTACTGGATTATAGAAGAGAAAATTCACATCTGCCTTGTTAATCTA ATAAATATAATTACAGCCCCTTAATGTGTTGTCAATGAGTCTAAGTTGACAAATTCAGTGGCAGCCCAGCCACCTCCTATCAATCAATCA GGGAAGAAATGCAGGGGAGACTGGGGCCCTCAGTGAGGGGCTGCCTGGCATTACTCCTCCAAAGACTGCTGCCCCCAGAACAGGCAGGGG GTGTGGGAGGGCCAGTTTCCCGCCACTGGGTCCAAGGAGCCTTTGTTCAAAGGAAGAAGTGGGCCACGGAAGAACGGGCCTGCTTCTCTC GTGCCTGTGCTTCTGACCTCCAGGAACTGTAAACAGGAACACCTATGTGTAACTGAAGGCATGAGACATCTGTACAGGAAGCATCCCAGC GCCCACATGGGCATGAGACAGTCTGCACTGCGCCTGGTGAAATGCGTGTGTGTACAGACAGTCCACTGGGCAGCACAGGTATCCTCATGT >68925_68925_11_PRMT2-STX18_PRMT2_chr21_48068531_ENST00000397638_STX18_chr4_4473433_ENST00000306200_length(amino acids)=442AA_BP=163 MATSGDCPRSESQGEEPAECSEAGLLQEGVQPEEFVAIADYAATDETQLSFLRGEKILILRQTTADWWWGERAGCCGYIPANHVGKHVDE YDPEDTWQDEEYFGSYGTLKLHLEMLADQPRTTKYHSVILQNKESLTDKVILDVGCGTGIISLFCAHYARPRAISHIGKLRDFLLEHRKD YINAYSHTMSEYGRMTDTERDQIDQDAQIFMRTCSEAIQQLRTEAHKEIHSQQVKEHRTAVLDFIEDYLKRVCKLYSEQRAIRVKRVVDK KRLSKLEPEPNTKTRESTSSEKVSQSPSKDSEENPATEERPEKILAETQPELGTWGDGKGEDELSPEEIQMFEQENQRLIGEMNSLFDEV -------------------------------------------------------------- >68925_68925_12_PRMT2-STX18_PRMT2_chr21_48068531_ENST00000397638_STX18_chr4_4473433_ENST00000505286_length(transcript)=1860nt_BP=694nt CGGGCCCTGGGCGGGGCCTTCCCGGCTGACGGCCTGCGTGCACTGCGCTTGCGCGGGTTGAGGGCGGTGGCTCAGGCTCCTGGAAAGGAC CGTCCACCCCTCCGCGCTGGCGGTGTGGACGCGGAACTCAGCGGAGAAACGCGATTGAGAAATGGAAAAGAAAATGAAATAAATCAGCAG TTATGAGGCAGAGCCTAAGAGAACTATGGCAACATCAGGTGACTGTCCCAGAAGTGAATCGCAGGGAGAAGAGCCTGCTGAGTGCAGTGA GGCCGGTCTCCTGCAGGAGGGAGTACAGCCAGAGGAGTTTGTGGCCATCGCGGACTACGCTGCCACCGATGAGACCCAGCTCAGTTTTTT GAGAGGAGAAAAAATTCTTATCCTGAGACAAACCACTGCAGATTGGTGGTGGGGTGAGCGTGCGGGCTGCTGTGGGTACATTCCGGCAAA CCATGTGGGGAAGCACGTGGATGAGTACGACCCCGAGGACACGTGGCAGGATGAAGAGTACTTCGGCAGCTATGGAACTCTGAAACTCCA CTTGGAGATGTTGGCAGACCAGCCACGAACAACTAAATACCACAGTGTCATCCTGCAGAATAAAGAATCCCTGACGGATAAAGTCATCCT GGACGTGGGCTGTGGGACTGGGATCATCAGTCTCTTCTGTGCACACTATGCGCGGCCTAGAGCGATTTCTCACATTGGCAAACTGAGAGA TTTTCTTCTGGAACACAGGAAAGATTATATTAATGCTTATAGCCATACCATGTCTGAATATGGGAGGATGACAGACACAGAACGAGACCA GATAGACCAGGATGCCCAGATATTCATGAGGACCTGTTCAGAAGCAATTCAGCAACTACGAACAGAAGCTCACAAGGAGATACATTCCCA GCAAGTGAAGGAGCACAGGACCGCTGTTTTGGATTTCATTGAAGATTACTTGAAAAGAGTATGTAAACTTTACTCAGAACAGAGAGCCAT CCGAGTTAAAAGAGTGGTGGATAAGAAAAGATTATCTAAGCTGGAACCAGAACCAAATACAAAGACAAGAGAATCCACATCTTCTGAGAA AGTTTCACAGAGTCCTTCAAAAGACTCTGAAGAAAACCCTGCCACTGAAGAACGTCCAGAAAAAATTTTGGCTGAAACACAACCTGAATT GGGAACGTGGGGAGATGGCAAAGGCGAAGATGAGTTATCCCCAGAAGAAATACAAATGTTTGAACAGGAAAATCAGCGACTAATTGGTGA AATGAACAGCTTGTTTGATGAAGTGAGGCAAATCGAAGGGAGAGTGGTTGAGATTTCCAGACTCCAAGAGATATTCACGGAAAAGGTTTT GCAACAGGAAGCTGAGATTGACAGCATTCACCAGTTAGTTGTGGGGGCAACTGAAAATATCAAGGAAGGCAACGAAGACATAAGAGAGGT CCCTCACCTATAAAATGCGGCCAATGAGTCACACCACCGTGTTGCTGAGGACTCAAGTCAATGCACAGTGGCTCAAGTAAAGAAGCCAGG ATGTGCCCCAGGTCACAGTGTGGACAGAAAAGAAAGCCAAAAGACACCACTGAAGTACAGCCCTTTTATCAACAGCGTCTTGATCTCAGT CCCACCAGGACGTCGGGAAGCACCTGACACGCTACAGAACAAACAGCCCATTCAGACCAGCAGCGCGTGCATCAGGAAGGAGGCTCTGCA GGCCAGACAAACTCCCCTCCAGCCTCACCGCCACGCCCCTTCACGCTGTCCTCTCCATCTGCTGCTCGTCATCCCTCAGGGAAACGGACC >68925_68925_12_PRMT2-STX18_PRMT2_chr21_48068531_ENST00000397638_STX18_chr4_4473433_ENST00000505286_length(amino acids)=415AA_BP=163 MATSGDCPRSESQGEEPAECSEAGLLQEGVQPEEFVAIADYAATDETQLSFLRGEKILILRQTTADWWWGERAGCCGYIPANHVGKHVDE YDPEDTWQDEEYFGSYGTLKLHLEMLADQPRTTKYHSVILQNKESLTDKVILDVGCGTGIISLFCAHYARPRAISHIGKLRDFLLEHRKD YINAYSHTMSEYGRMTDTERDQIDQDAQIFMRTCSEAIQQLRTEAHKEIHSQQVKEHRTAVLDFIEDYLKRVCKLYSEQRAIRVKRVVDK KRLSKLEPEPNTKTRESTSSEKVSQSPSKDSEENPATEERPEKILAETQPELGTWGDGKGEDELSPEEIQMFEQENQRLIGEMNSLFDEV -------------------------------------------------------------- >68925_68925_13_PRMT2-STX18_PRMT2_chr21_48068531_ENST00000440086_STX18_chr4_4473433_ENST00000306200_length(transcript)=2534nt_BP=628nt GTGGCTCAGGCTCCTGGAAAGGACCGTCCACCCCTCCGCGCTGGCGGTGTGGACGCGGAACTCAGCGGAGAAACGCGATTGAGAAATGGA AAAGAAAATGAAATAAATCAGCAGTTATGAGGCAGAGCCTAAGAGAACTATGGCAACATCAGGTGACTGTCCCAGAAGTGAATCGCAGGG AGAAGAGCCTGCTGAGTGCAGTGAGGCCGGTCTCCTGCAGGAGGGAGTACAGCCAGAGGAGTTTGTGGCCATCGCGGACTACGCTGCCAC CGATGAGACCCAGCTCAGTTTTTTGAGAGGAGAAAAAATTCTTATCCTGAGACAAACCACTGCAGATTGGTGGTGGGGTGAGCGTGCGGG CTGCTGTGGGTACATTCCGGCAAACCATGTGGGGAAGCACGTGGATGAGTACGACCCCGAGGACACGTGGCAGGATGAAGAGTACTTCGG CAGCTATGGAACTCTGAAACTCCACTTGGAGATGTTGGCAGACCAGCCACGAACAACTAAATACCACAGTGTCATCCTGCAGAATAAAGA ATCCCTGACGGATAAAGTCATCCTGGACGTGGGCTGTGGGACTGGGATCATCAGTCTCTTCTGTGCACACTATGCGCGGCCTAGAGCGAT TTCTCACATTGGCAAACTGAGAGATTTTCTTCTGGAACACAGGAAAGATTATATTAATGCTTATAGCCATACCATGTCTGAATATGGGAG GATGACAGACACAGAACGAGACCAGATAGACCAGGATGCCCAGATATTCATGAGGACCTGTTCAGAAGCAATTCAGCAACTACGAACAGA AGCTCACAAGGAGATACATTCCCAGCAAGTGAAGGAGCACAGGACCGCTGTTTTGGATTTCATTGAAGATTACTTGAAAAGAGTATGTAA ACTTTACTCAGAACAGAGAGCCATCCGAGTTAAAAGAGTGGTGGATAAGAAAAGATTATCTAAGCTGGAACCAGAACCAAATACAAAGAC AAGAGAATCCACATCTTCTGAGAAAGTTTCACAGAGTCCTTCAAAAGACTCTGAAGAAAACCCTGCCACTGAAGAACGTCCAGAAAAAAT TTTGGCTGAAACACAACCTGAATTGGGAACGTGGGGAGATGGCAAAGGCGAAGATGAGTTATCCCCAGAAGAAATACAAATGTTTGAACA GGAAAATCAGCGACTAATTGGTGAAATGAACAGCTTGTTTGATGAAGTGAGGCAAATCGAAGGGAGAGTGGTTGAGATTTCCAGACTCCA AGAGATATTCACGGAAAAGGTTTTGCAACAGGAAGCTGAGATTGACAGCATTCACCAGTTAGTTGTGGGGGCAACTGAAAATATCAAGGA AGGCAACGAAGACATAAGAGAGGCCATTAAAAACAACGCTGGCTTCCGCGTGTGGATCCTCTTCTTCCTCGTGATGTGCTCCTTCTCCTT GCTCTTCCTCGACTGGTACGACAGCTAGCCAGGGCCACGGGGGCCCAGCACGAGAGTCCTCATGGGCACTCACAGACTGCGTGCTTTCAT GTACTTCCAGTGCTGGAGCATGGTATGACCAGATTTTATCACAGTGCCATTTGAAGGGAAAGGAGTTCAGACAGACAGACGTATTCCCCA AAAAGGGATACCCCAGGCCGATGGTGTTCAGCCATTTAGCAGCTGAAAAAGGAAACAGTGCACACCAATGGGAGGCAGCCTGCGTAGCCC TCATCAGGCAAGACAGACTGAATGCAGGAGTGGGTGATTAGCTGCTCCTTGAACTTGAGGCTGCCTTGGCAGCAGGGGCACAGCAGGCCT CAAGAGCCCCTAATTGTCTCAGGGTTCAAAGGAAGACACTGACCTTTCCCATCCCGGTAGCTTCAGGGAAGATCATAGTTAATAACGTCT CTCAACAAATGATTACTTCTTTGTTTCCTTGTGGCTTCTTGTCTGTCTGAGTCAACGAATACACAGACTTACTGGATTATAGAAGAGAAA ATTCACATCTGCCTTGTTAATCTAATAAATATAATTACAGCCCCTTAATGTGTTGTCAATGAGTCTAAGTTGACAAATTCAGTGGCAGCC CAGCCACCTCCTATCAATCAATCAGGGAAGAAATGCAGGGGAGACTGGGGCCCTCAGTGAGGGGCTGCCTGGCATTACTCCTCCAAAGAC TGCTGCCCCCAGAACAGGCAGGGGGTGTGGGAGGGCCAGTTTCCCGCCACTGGGTCCAAGGAGCCTTTGTTCAAAGGAAGAAGTGGGCCA CGGAAGAACGGGCCTGCTTCTCTCGTGCCTGTGCTTCTGACCTCCAGGAACTGTAAACAGGAACACCTATGTGTAACTGAAGGCATGAGA CATCTGTACAGGAAGCATCCCAGCGCCCACATGGGCATGAGACAGTCTGCACTGCGCCTGGTGAAATGCGTGTGTGTACAGACAGTCCAC TGGGCAGCACAGGTATCCTCATGTTCTTTATTTGCACAGAGTGAAATGTCAGAAGTTACATGTAAATGAATTCACAGTCAATAAAGTCCA >68925_68925_13_PRMT2-STX18_PRMT2_chr21_48068531_ENST00000440086_STX18_chr4_4473433_ENST00000306200_length(amino acids)=442AA_BP=163 MATSGDCPRSESQGEEPAECSEAGLLQEGVQPEEFVAIADYAATDETQLSFLRGEKILILRQTTADWWWGERAGCCGYIPANHVGKHVDE YDPEDTWQDEEYFGSYGTLKLHLEMLADQPRTTKYHSVILQNKESLTDKVILDVGCGTGIISLFCAHYARPRAISHIGKLRDFLLEHRKD YINAYSHTMSEYGRMTDTERDQIDQDAQIFMRTCSEAIQQLRTEAHKEIHSQQVKEHRTAVLDFIEDYLKRVCKLYSEQRAIRVKRVVDK KRLSKLEPEPNTKTRESTSSEKVSQSPSKDSEENPATEERPEKILAETQPELGTWGDGKGEDELSPEEIQMFEQENQRLIGEMNSLFDEV -------------------------------------------------------------- >68925_68925_14_PRMT2-STX18_PRMT2_chr21_48068531_ENST00000440086_STX18_chr4_4473433_ENST00000505286_length(transcript)=1794nt_BP=628nt GTGGCTCAGGCTCCTGGAAAGGACCGTCCACCCCTCCGCGCTGGCGGTGTGGACGCGGAACTCAGCGGAGAAACGCGATTGAGAAATGGA AAAGAAAATGAAATAAATCAGCAGTTATGAGGCAGAGCCTAAGAGAACTATGGCAACATCAGGTGACTGTCCCAGAAGTGAATCGCAGGG AGAAGAGCCTGCTGAGTGCAGTGAGGCCGGTCTCCTGCAGGAGGGAGTACAGCCAGAGGAGTTTGTGGCCATCGCGGACTACGCTGCCAC CGATGAGACCCAGCTCAGTTTTTTGAGAGGAGAAAAAATTCTTATCCTGAGACAAACCACTGCAGATTGGTGGTGGGGTGAGCGTGCGGG CTGCTGTGGGTACATTCCGGCAAACCATGTGGGGAAGCACGTGGATGAGTACGACCCCGAGGACACGTGGCAGGATGAAGAGTACTTCGG CAGCTATGGAACTCTGAAACTCCACTTGGAGATGTTGGCAGACCAGCCACGAACAACTAAATACCACAGTGTCATCCTGCAGAATAAAGA ATCCCTGACGGATAAAGTCATCCTGGACGTGGGCTGTGGGACTGGGATCATCAGTCTCTTCTGTGCACACTATGCGCGGCCTAGAGCGAT TTCTCACATTGGCAAACTGAGAGATTTTCTTCTGGAACACAGGAAAGATTATATTAATGCTTATAGCCATACCATGTCTGAATATGGGAG GATGACAGACACAGAACGAGACCAGATAGACCAGGATGCCCAGATATTCATGAGGACCTGTTCAGAAGCAATTCAGCAACTACGAACAGA AGCTCACAAGGAGATACATTCCCAGCAAGTGAAGGAGCACAGGACCGCTGTTTTGGATTTCATTGAAGATTACTTGAAAAGAGTATGTAA ACTTTACTCAGAACAGAGAGCCATCCGAGTTAAAAGAGTGGTGGATAAGAAAAGATTATCTAAGCTGGAACCAGAACCAAATACAAAGAC AAGAGAATCCACATCTTCTGAGAAAGTTTCACAGAGTCCTTCAAAAGACTCTGAAGAAAACCCTGCCACTGAAGAACGTCCAGAAAAAAT TTTGGCTGAAACACAACCTGAATTGGGAACGTGGGGAGATGGCAAAGGCGAAGATGAGTTATCCCCAGAAGAAATACAAATGTTTGAACA GGAAAATCAGCGACTAATTGGTGAAATGAACAGCTTGTTTGATGAAGTGAGGCAAATCGAAGGGAGAGTGGTTGAGATTTCCAGACTCCA AGAGATATTCACGGAAAAGGTTTTGCAACAGGAAGCTGAGATTGACAGCATTCACCAGTTAGTTGTGGGGGCAACTGAAAATATCAAGGA AGGCAACGAAGACATAAGAGAGGTCCCTCACCTATAAAATGCGGCCAATGAGTCACACCACCGTGTTGCTGAGGACTCAAGTCAATGCAC AGTGGCTCAAGTAAAGAAGCCAGGATGTGCCCCAGGTCACAGTGTGGACAGAAAAGAAAGCCAAAAGACACCACTGAAGTACAGCCCTTT TATCAACAGCGTCTTGATCTCAGTCCCACCAGGACGTCGGGAAGCACCTGACACGCTACAGAACAAACAGCCCATTCAGACCAGCAGCGC GTGCATCAGGAAGGAGGCTCTGCAGGCCAGACAAACTCCCCTCCAGCCTCACCGCCACGCCCCTTCACGCTGTCCTCTCCATCTGCTGCT >68925_68925_14_PRMT2-STX18_PRMT2_chr21_48068531_ENST00000440086_STX18_chr4_4473433_ENST00000505286_length(amino acids)=415AA_BP=163 MATSGDCPRSESQGEEPAECSEAGLLQEGVQPEEFVAIADYAATDETQLSFLRGEKILILRQTTADWWWGERAGCCGYIPANHVGKHVDE YDPEDTWQDEEYFGSYGTLKLHLEMLADQPRTTKYHSVILQNKESLTDKVILDVGCGTGIISLFCAHYARPRAISHIGKLRDFLLEHRKD YINAYSHTMSEYGRMTDTERDQIDQDAQIFMRTCSEAIQQLRTEAHKEIHSQQVKEHRTAVLDFIEDYLKRVCKLYSEQRAIRVKRVVDK KRLSKLEPEPNTKTRESTSSEKVSQSPSKDSEENPATEERPEKILAETQPELGTWGDGKGEDELSPEEIQMFEQENQRLIGEMNSLFDEV -------------------------------------------------------------- >68925_68925_15_PRMT2-STX18_PRMT2_chr21_48068531_ENST00000451211_STX18_chr4_4473433_ENST00000306200_length(transcript)=2570nt_BP=664nt GGCCTGCGTGCACTGCGCTTGCGCGGGTTGAGGGCGGTGGCTCAGGCTCCTGGAAAGGACCGTCCACCCCTCCGCGCTGGCGGTGTGGAC GCGGAACTCAGCGGAGAAACGCGATTGAGAAATGGAAAAGAAAATGAAATAAATCAGCAGTTATGAGGCAGAGCCTAAGAGAACTATGGC AACATCAGGTGACTGTCCCAGAAGTGAATCGCAGGGAGAAGAGCCTGCTGAGTGCAGTGAGGCCGGTCTCCTGCAGGAGGGAGTACAGCC AGAGGAGTTTGTGGCCATCGCGGACTACGCTGCCACCGATGAGACCCAGCTCAGTTTTTTGAGAGGAGAAAAAATTCTTATCCTGAGACA AACCACTGCAGATTGGTGGTGGGGTGAGCGTGCGGGCTGCTGTGGGTACATTCCGGCAAACCATGTGGGGAAGCACGTGGATGAGTACGA CCCCGAGGACACGTGGCAGGATGAAGAGTACTTCGGCAGCTATGGAACTCTGAAACTCCACTTGGAGATGTTGGCAGACCAGCCACGAAC AACTAAATACCACAGTGTCATCCTGCAGAATAAAGAATCCCTGACGGATAAAGTCATCCTGGACGTGGGCTGTGGGACTGGGATCATCAG TCTCTTCTGTGCACACTATGCGCGGCCTAGAGCGATTTCTCACATTGGCAAACTGAGAGATTTTCTTCTGGAACACAGGAAAGATTATAT TAATGCTTATAGCCATACCATGTCTGAATATGGGAGGATGACAGACACAGAACGAGACCAGATAGACCAGGATGCCCAGATATTCATGAG GACCTGTTCAGAAGCAATTCAGCAACTACGAACAGAAGCTCACAAGGAGATACATTCCCAGCAAGTGAAGGAGCACAGGACCGCTGTTTT GGATTTCATTGAAGATTACTTGAAAAGAGTATGTAAACTTTACTCAGAACAGAGAGCCATCCGAGTTAAAAGAGTGGTGGATAAGAAAAG ATTATCTAAGCTGGAACCAGAACCAAATACAAAGACAAGAGAATCCACATCTTCTGAGAAAGTTTCACAGAGTCCTTCAAAAGACTCTGA AGAAAACCCTGCCACTGAAGAACGTCCAGAAAAAATTTTGGCTGAAACACAACCTGAATTGGGAACGTGGGGAGATGGCAAAGGCGAAGA TGAGTTATCCCCAGAAGAAATACAAATGTTTGAACAGGAAAATCAGCGACTAATTGGTGAAATGAACAGCTTGTTTGATGAAGTGAGGCA AATCGAAGGGAGAGTGGTTGAGATTTCCAGACTCCAAGAGATATTCACGGAAAAGGTTTTGCAACAGGAAGCTGAGATTGACAGCATTCA CCAGTTAGTTGTGGGGGCAACTGAAAATATCAAGGAAGGCAACGAAGACATAAGAGAGGCCATTAAAAACAACGCTGGCTTCCGCGTGTG GATCCTCTTCTTCCTCGTGATGTGCTCCTTCTCCTTGCTCTTCCTCGACTGGTACGACAGCTAGCCAGGGCCACGGGGGCCCAGCACGAG AGTCCTCATGGGCACTCACAGACTGCGTGCTTTCATGTACTTCCAGTGCTGGAGCATGGTATGACCAGATTTTATCACAGTGCCATTTGA AGGGAAAGGAGTTCAGACAGACAGACGTATTCCCCAAAAAGGGATACCCCAGGCCGATGGTGTTCAGCCATTTAGCAGCTGAAAAAGGAA ACAGTGCACACCAATGGGAGGCAGCCTGCGTAGCCCTCATCAGGCAAGACAGACTGAATGCAGGAGTGGGTGATTAGCTGCTCCTTGAAC TTGAGGCTGCCTTGGCAGCAGGGGCACAGCAGGCCTCAAGAGCCCCTAATTGTCTCAGGGTTCAAAGGAAGACACTGACCTTTCCCATCC CGGTAGCTTCAGGGAAGATCATAGTTAATAACGTCTCTCAACAAATGATTACTTCTTTGTTTCCTTGTGGCTTCTTGTCTGTCTGAGTCA ACGAATACACAGACTTACTGGATTATAGAAGAGAAAATTCACATCTGCCTTGTTAATCTAATAAATATAATTACAGCCCCTTAATGTGTT GTCAATGAGTCTAAGTTGACAAATTCAGTGGCAGCCCAGCCACCTCCTATCAATCAATCAGGGAAGAAATGCAGGGGAGACTGGGGCCCT CAGTGAGGGGCTGCCTGGCATTACTCCTCCAAAGACTGCTGCCCCCAGAACAGGCAGGGGGTGTGGGAGGGCCAGTTTCCCGCCACTGGG TCCAAGGAGCCTTTGTTCAAAGGAAGAAGTGGGCCACGGAAGAACGGGCCTGCTTCTCTCGTGCCTGTGCTTCTGACCTCCAGGAACTGT AAACAGGAACACCTATGTGTAACTGAAGGCATGAGACATCTGTACAGGAAGCATCCCAGCGCCCACATGGGCATGAGACAGTCTGCACTG CGCCTGGTGAAATGCGTGTGTGTACAGACAGTCCACTGGGCAGCACAGGTATCCTCATGTTCTTTATTTGCACAGAGTGAAATGTCAGAA >68925_68925_15_PRMT2-STX18_PRMT2_chr21_48068531_ENST00000451211_STX18_chr4_4473433_ENST00000306200_length(amino acids)=442AA_BP=163 MATSGDCPRSESQGEEPAECSEAGLLQEGVQPEEFVAIADYAATDETQLSFLRGEKILILRQTTADWWWGERAGCCGYIPANHVGKHVDE YDPEDTWQDEEYFGSYGTLKLHLEMLADQPRTTKYHSVILQNKESLTDKVILDVGCGTGIISLFCAHYARPRAISHIGKLRDFLLEHRKD YINAYSHTMSEYGRMTDTERDQIDQDAQIFMRTCSEAIQQLRTEAHKEIHSQQVKEHRTAVLDFIEDYLKRVCKLYSEQRAIRVKRVVDK KRLSKLEPEPNTKTRESTSSEKVSQSPSKDSEENPATEERPEKILAETQPELGTWGDGKGEDELSPEEIQMFEQENQRLIGEMNSLFDEV -------------------------------------------------------------- >68925_68925_16_PRMT2-STX18_PRMT2_chr21_48068531_ENST00000451211_STX18_chr4_4473433_ENST00000505286_length(transcript)=1830nt_BP=664nt GGCCTGCGTGCACTGCGCTTGCGCGGGTTGAGGGCGGTGGCTCAGGCTCCTGGAAAGGACCGTCCACCCCTCCGCGCTGGCGGTGTGGAC GCGGAACTCAGCGGAGAAACGCGATTGAGAAATGGAAAAGAAAATGAAATAAATCAGCAGTTATGAGGCAGAGCCTAAGAGAACTATGGC AACATCAGGTGACTGTCCCAGAAGTGAATCGCAGGGAGAAGAGCCTGCTGAGTGCAGTGAGGCCGGTCTCCTGCAGGAGGGAGTACAGCC AGAGGAGTTTGTGGCCATCGCGGACTACGCTGCCACCGATGAGACCCAGCTCAGTTTTTTGAGAGGAGAAAAAATTCTTATCCTGAGACA AACCACTGCAGATTGGTGGTGGGGTGAGCGTGCGGGCTGCTGTGGGTACATTCCGGCAAACCATGTGGGGAAGCACGTGGATGAGTACGA CCCCGAGGACACGTGGCAGGATGAAGAGTACTTCGGCAGCTATGGAACTCTGAAACTCCACTTGGAGATGTTGGCAGACCAGCCACGAAC AACTAAATACCACAGTGTCATCCTGCAGAATAAAGAATCCCTGACGGATAAAGTCATCCTGGACGTGGGCTGTGGGACTGGGATCATCAG TCTCTTCTGTGCACACTATGCGCGGCCTAGAGCGATTTCTCACATTGGCAAACTGAGAGATTTTCTTCTGGAACACAGGAAAGATTATAT TAATGCTTATAGCCATACCATGTCTGAATATGGGAGGATGACAGACACAGAACGAGACCAGATAGACCAGGATGCCCAGATATTCATGAG GACCTGTTCAGAAGCAATTCAGCAACTACGAACAGAAGCTCACAAGGAGATACATTCCCAGCAAGTGAAGGAGCACAGGACCGCTGTTTT GGATTTCATTGAAGATTACTTGAAAAGAGTATGTAAACTTTACTCAGAACAGAGAGCCATCCGAGTTAAAAGAGTGGTGGATAAGAAAAG ATTATCTAAGCTGGAACCAGAACCAAATACAAAGACAAGAGAATCCACATCTTCTGAGAAAGTTTCACAGAGTCCTTCAAAAGACTCTGA AGAAAACCCTGCCACTGAAGAACGTCCAGAAAAAATTTTGGCTGAAACACAACCTGAATTGGGAACGTGGGGAGATGGCAAAGGCGAAGA TGAGTTATCCCCAGAAGAAATACAAATGTTTGAACAGGAAAATCAGCGACTAATTGGTGAAATGAACAGCTTGTTTGATGAAGTGAGGCA AATCGAAGGGAGAGTGGTTGAGATTTCCAGACTCCAAGAGATATTCACGGAAAAGGTTTTGCAACAGGAAGCTGAGATTGACAGCATTCA CCAGTTAGTTGTGGGGGCAACTGAAAATATCAAGGAAGGCAACGAAGACATAAGAGAGGTCCCTCACCTATAAAATGCGGCCAATGAGTC ACACCACCGTGTTGCTGAGGACTCAAGTCAATGCACAGTGGCTCAAGTAAAGAAGCCAGGATGTGCCCCAGGTCACAGTGTGGACAGAAA AGAAAGCCAAAAGACACCACTGAAGTACAGCCCTTTTATCAACAGCGTCTTGATCTCAGTCCCACCAGGACGTCGGGAAGCACCTGACAC GCTACAGAACAAACAGCCCATTCAGACCAGCAGCGCGTGCATCAGGAAGGAGGCTCTGCAGGCCAGACAAACTCCCCTCCAGCCTCACCG CCACGCCCCTTCACGCTGTCCTCTCCATCTGCTGCTCGTCATCCCTCAGGGAAACGGACCAAGGGTTCCCCTCTTCCCTCCCACCTCGGC >68925_68925_16_PRMT2-STX18_PRMT2_chr21_48068531_ENST00000451211_STX18_chr4_4473433_ENST00000505286_length(amino acids)=415AA_BP=163 MATSGDCPRSESQGEEPAECSEAGLLQEGVQPEEFVAIADYAATDETQLSFLRGEKILILRQTTADWWWGERAGCCGYIPANHVGKHVDE YDPEDTWQDEEYFGSYGTLKLHLEMLADQPRTTKYHSVILQNKESLTDKVILDVGCGTGIISLFCAHYARPRAISHIGKLRDFLLEHRKD YINAYSHTMSEYGRMTDTERDQIDQDAQIFMRTCSEAIQQLRTEAHKEIHSQQVKEHRTAVLDFIEDYLKRVCKLYSEQRAIRVKRVVDK KRLSKLEPEPNTKTRESTSSEKVSQSPSKDSEENPATEERPEKILAETQPELGTWGDGKGEDELSPEEIQMFEQENQRLIGEMNSLFDEV -------------------------------------------------------------- >68925_68925_17_PRMT2-STX18_PRMT2_chr21_48068531_ENST00000458387_STX18_chr4_4473433_ENST00000306200_length(transcript)=2570nt_BP=664nt GGCCTGCGTGCACTGCGCTTGCGCGGGTTGAGGGCGGTGGCTCAGGCTCCTGGAAAGGACCGTCCACCCCTCCGCGCTGGCGGTGTGGAC GCGGAACTCAGCGGAGAAACGCGATTGAGAAATGGAAAAGAAAATGAAATAAATCAGCAGTTATGAGGCAGAGCCTAAGAGAACTATGGC AACATCAGGTGACTGTCCCAGAAGTGAATCGCAGGGAGAAGAGCCTGCTGAGTGCAGTGAGGCCGGTCTCCTGCAGGAGGGAGTACAGCC AGAGGAGTTTGTGGCCATCGCGGACTACGCTGCCACCGATGAGACCCAGCTCAGTTTTTTGAGAGGAGAAAAAATTCTTATCCTGAGACA AACCACTGCAGATTGGTGGTGGGGTGAGCGTGCGGGCTGCTGTGGGTACATTCCGGCAAACCATGTGGGGAAGCACGTGGATGAGTACGA CCCCGAGGACACGTGGCAGGATGAAGAGTACTTCGGCAGCTATGGAACTCTGAAACTCCACTTGGAGATGTTGGCAGACCAGCCACGAAC AACTAAATACCACAGTGTCATCCTGCAGAATAAAGAATCCCTGACGGATAAAGTCATCCTGGACGTGGGCTGTGGGACTGGGATCATCAG TCTCTTCTGTGCACACTATGCGCGGCCTAGAGCGATTTCTCACATTGGCAAACTGAGAGATTTTCTTCTGGAACACAGGAAAGATTATAT TAATGCTTATAGCCATACCATGTCTGAATATGGGAGGATGACAGACACAGAACGAGACCAGATAGACCAGGATGCCCAGATATTCATGAG GACCTGTTCAGAAGCAATTCAGCAACTACGAACAGAAGCTCACAAGGAGATACATTCCCAGCAAGTGAAGGAGCACAGGACCGCTGTTTT GGATTTCATTGAAGATTACTTGAAAAGAGTATGTAAACTTTACTCAGAACAGAGAGCCATCCGAGTTAAAAGAGTGGTGGATAAGAAAAG ATTATCTAAGCTGGAACCAGAACCAAATACAAAGACAAGAGAATCCACATCTTCTGAGAAAGTTTCACAGAGTCCTTCAAAAGACTCTGA AGAAAACCCTGCCACTGAAGAACGTCCAGAAAAAATTTTGGCTGAAACACAACCTGAATTGGGAACGTGGGGAGATGGCAAAGGCGAAGA TGAGTTATCCCCAGAAGAAATACAAATGTTTGAACAGGAAAATCAGCGACTAATTGGTGAAATGAACAGCTTGTTTGATGAAGTGAGGCA AATCGAAGGGAGAGTGGTTGAGATTTCCAGACTCCAAGAGATATTCACGGAAAAGGTTTTGCAACAGGAAGCTGAGATTGACAGCATTCA CCAGTTAGTTGTGGGGGCAACTGAAAATATCAAGGAAGGCAACGAAGACATAAGAGAGGCCATTAAAAACAACGCTGGCTTCCGCGTGTG GATCCTCTTCTTCCTCGTGATGTGCTCCTTCTCCTTGCTCTTCCTCGACTGGTACGACAGCTAGCCAGGGCCACGGGGGCCCAGCACGAG AGTCCTCATGGGCACTCACAGACTGCGTGCTTTCATGTACTTCCAGTGCTGGAGCATGGTATGACCAGATTTTATCACAGTGCCATTTGA AGGGAAAGGAGTTCAGACAGACAGACGTATTCCCCAAAAAGGGATACCCCAGGCCGATGGTGTTCAGCCATTTAGCAGCTGAAAAAGGAA ACAGTGCACACCAATGGGAGGCAGCCTGCGTAGCCCTCATCAGGCAAGACAGACTGAATGCAGGAGTGGGTGATTAGCTGCTCCTTGAAC TTGAGGCTGCCTTGGCAGCAGGGGCACAGCAGGCCTCAAGAGCCCCTAATTGTCTCAGGGTTCAAAGGAAGACACTGACCTTTCCCATCC CGGTAGCTTCAGGGAAGATCATAGTTAATAACGTCTCTCAACAAATGATTACTTCTTTGTTTCCTTGTGGCTTCTTGTCTGTCTGAGTCA ACGAATACACAGACTTACTGGATTATAGAAGAGAAAATTCACATCTGCCTTGTTAATCTAATAAATATAATTACAGCCCCTTAATGTGTT GTCAATGAGTCTAAGTTGACAAATTCAGTGGCAGCCCAGCCACCTCCTATCAATCAATCAGGGAAGAAATGCAGGGGAGACTGGGGCCCT CAGTGAGGGGCTGCCTGGCATTACTCCTCCAAAGACTGCTGCCCCCAGAACAGGCAGGGGGTGTGGGAGGGCCAGTTTCCCGCCACTGGG TCCAAGGAGCCTTTGTTCAAAGGAAGAAGTGGGCCACGGAAGAACGGGCCTGCTTCTCTCGTGCCTGTGCTTCTGACCTCCAGGAACTGT AAACAGGAACACCTATGTGTAACTGAAGGCATGAGACATCTGTACAGGAAGCATCCCAGCGCCCACATGGGCATGAGACAGTCTGCACTG CGCCTGGTGAAATGCGTGTGTGTACAGACAGTCCACTGGGCAGCACAGGTATCCTCATGTTCTTTATTTGCACAGAGTGAAATGTCAGAA >68925_68925_17_PRMT2-STX18_PRMT2_chr21_48068531_ENST00000458387_STX18_chr4_4473433_ENST00000306200_length(amino acids)=442AA_BP=163 MATSGDCPRSESQGEEPAECSEAGLLQEGVQPEEFVAIADYAATDETQLSFLRGEKILILRQTTADWWWGERAGCCGYIPANHVGKHVDE YDPEDTWQDEEYFGSYGTLKLHLEMLADQPRTTKYHSVILQNKESLTDKVILDVGCGTGIISLFCAHYARPRAISHIGKLRDFLLEHRKD YINAYSHTMSEYGRMTDTERDQIDQDAQIFMRTCSEAIQQLRTEAHKEIHSQQVKEHRTAVLDFIEDYLKRVCKLYSEQRAIRVKRVVDK KRLSKLEPEPNTKTRESTSSEKVSQSPSKDSEENPATEERPEKILAETQPELGTWGDGKGEDELSPEEIQMFEQENQRLIGEMNSLFDEV -------------------------------------------------------------- >68925_68925_18_PRMT2-STX18_PRMT2_chr21_48068531_ENST00000458387_STX18_chr4_4473433_ENST00000505286_length(transcript)=1830nt_BP=664nt GGCCTGCGTGCACTGCGCTTGCGCGGGTTGAGGGCGGTGGCTCAGGCTCCTGGAAAGGACCGTCCACCCCTCCGCGCTGGCGGTGTGGAC GCGGAACTCAGCGGAGAAACGCGATTGAGAAATGGAAAAGAAAATGAAATAAATCAGCAGTTATGAGGCAGAGCCTAAGAGAACTATGGC AACATCAGGTGACTGTCCCAGAAGTGAATCGCAGGGAGAAGAGCCTGCTGAGTGCAGTGAGGCCGGTCTCCTGCAGGAGGGAGTACAGCC AGAGGAGTTTGTGGCCATCGCGGACTACGCTGCCACCGATGAGACCCAGCTCAGTTTTTTGAGAGGAGAAAAAATTCTTATCCTGAGACA AACCACTGCAGATTGGTGGTGGGGTGAGCGTGCGGGCTGCTGTGGGTACATTCCGGCAAACCATGTGGGGAAGCACGTGGATGAGTACGA CCCCGAGGACACGTGGCAGGATGAAGAGTACTTCGGCAGCTATGGAACTCTGAAACTCCACTTGGAGATGTTGGCAGACCAGCCACGAAC AACTAAATACCACAGTGTCATCCTGCAGAATAAAGAATCCCTGACGGATAAAGTCATCCTGGACGTGGGCTGTGGGACTGGGATCATCAG TCTCTTCTGTGCACACTATGCGCGGCCTAGAGCGATTTCTCACATTGGCAAACTGAGAGATTTTCTTCTGGAACACAGGAAAGATTATAT TAATGCTTATAGCCATACCATGTCTGAATATGGGAGGATGACAGACACAGAACGAGACCAGATAGACCAGGATGCCCAGATATTCATGAG GACCTGTTCAGAAGCAATTCAGCAACTACGAACAGAAGCTCACAAGGAGATACATTCCCAGCAAGTGAAGGAGCACAGGACCGCTGTTTT GGATTTCATTGAAGATTACTTGAAAAGAGTATGTAAACTTTACTCAGAACAGAGAGCCATCCGAGTTAAAAGAGTGGTGGATAAGAAAAG ATTATCTAAGCTGGAACCAGAACCAAATACAAAGACAAGAGAATCCACATCTTCTGAGAAAGTTTCACAGAGTCCTTCAAAAGACTCTGA AGAAAACCCTGCCACTGAAGAACGTCCAGAAAAAATTTTGGCTGAAACACAACCTGAATTGGGAACGTGGGGAGATGGCAAAGGCGAAGA TGAGTTATCCCCAGAAGAAATACAAATGTTTGAACAGGAAAATCAGCGACTAATTGGTGAAATGAACAGCTTGTTTGATGAAGTGAGGCA AATCGAAGGGAGAGTGGTTGAGATTTCCAGACTCCAAGAGATATTCACGGAAAAGGTTTTGCAACAGGAAGCTGAGATTGACAGCATTCA CCAGTTAGTTGTGGGGGCAACTGAAAATATCAAGGAAGGCAACGAAGACATAAGAGAGGTCCCTCACCTATAAAATGCGGCCAATGAGTC ACACCACCGTGTTGCTGAGGACTCAAGTCAATGCACAGTGGCTCAAGTAAAGAAGCCAGGATGTGCCCCAGGTCACAGTGTGGACAGAAA AGAAAGCCAAAAGACACCACTGAAGTACAGCCCTTTTATCAACAGCGTCTTGATCTCAGTCCCACCAGGACGTCGGGAAGCACCTGACAC GCTACAGAACAAACAGCCCATTCAGACCAGCAGCGCGTGCATCAGGAAGGAGGCTCTGCAGGCCAGACAAACTCCCCTCCAGCCTCACCG CCACGCCCCTTCACGCTGTCCTCTCCATCTGCTGCTCGTCATCCCTCAGGGAAACGGACCAAGGGTTCCCCTCTTCCCTCCCACCTCGGC >68925_68925_18_PRMT2-STX18_PRMT2_chr21_48068531_ENST00000458387_STX18_chr4_4473433_ENST00000505286_length(amino acids)=415AA_BP=163 MATSGDCPRSESQGEEPAECSEAGLLQEGVQPEEFVAIADYAATDETQLSFLRGEKILILRQTTADWWWGERAGCCGYIPANHVGKHVDE YDPEDTWQDEEYFGSYGTLKLHLEMLADQPRTTKYHSVILQNKESLTDKVILDVGCGTGIISLFCAHYARPRAISHIGKLRDFLLEHRKD YINAYSHTMSEYGRMTDTERDQIDQDAQIFMRTCSEAIQQLRTEAHKEIHSQQVKEHRTAVLDFIEDYLKRVCKLYSEQRAIRVKRVVDK KRLSKLEPEPNTKTRESTSSEKVSQSPSKDSEENPATEERPEKILAETQPELGTWGDGKGEDELSPEEIQMFEQENQRLIGEMNSLFDEV -------------------------------------------------------------- |
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Fusion Gene PPI Analysis for PRMT2-STX18 |
| Go to ChiPPI (Chimeric Protein-Protein interactions) to see the chimeric PPI interaction in |
| Protein-protein interactors with each fusion partner protein in wild-type (BIOGRID-3.4.160) |
| Hgene | Hgene's interactors | Tgene | Tgene's interactors |
| - Retained PPIs in in-frame fusion. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Still interaction with |
| - Lost PPIs in in-frame fusion. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Interaction lost with |
| Hgene | PRMT2 | chr21:48068531 | chr4:4473433 | ENST00000334494 | + | 5 | 7 | 133_275 | 163.0 | 285.0 | ESR1 |
| Hgene | PRMT2 | chr21:48068531 | chr4:4473433 | ENST00000334494 | + | 5 | 7 | 1_277 | 163.0 | 285.0 | ESR1 |
| Hgene | PRMT2 | chr21:48068531 | chr4:4473433 | ENST00000355680 | + | 6 | 12 | 133_275 | 163.0 | 434.0 | ESR1 |
| Hgene | PRMT2 | chr21:48068531 | chr4:4473433 | ENST00000355680 | + | 6 | 12 | 1_277 | 163.0 | 434.0 | ESR1 |
| Hgene | PRMT2 | chr21:48068531 | chr4:4473433 | ENST00000397637 | + | 5 | 11 | 133_275 | 163.0 | 434.0 | ESR1 |
| Hgene | PRMT2 | chr21:48068531 | chr4:4473433 | ENST00000397637 | + | 5 | 11 | 1_277 | 163.0 | 434.0 | ESR1 |
| Hgene | PRMT2 | chr21:48068531 | chr4:4473433 | ENST00000397638 | + | 5 | 11 | 133_275 | 163.0 | 434.0 | ESR1 |
| Hgene | PRMT2 | chr21:48068531 | chr4:4473433 | ENST00000397638 | + | 5 | 11 | 1_277 | 163.0 | 434.0 | ESR1 |
| Hgene | PRMT2 | chr21:48068531 | chr4:4473433 | ENST00000440086 | + | 5 | 9 | 133_275 | 163.0 | 332.0 | ESR1 |
| Hgene | PRMT2 | chr21:48068531 | chr4:4473433 | ENST00000440086 | + | 5 | 9 | 1_277 | 163.0 | 332.0 | ESR1 |
| Hgene | PRMT2 | chr21:48068531 | chr4:4473433 | ENST00000334494 | + | 5 | 7 | 83_207 | 163.0 | 285.0 | RB1 |
| Hgene | PRMT2 | chr21:48068531 | chr4:4473433 | ENST00000355680 | + | 6 | 12 | 83_207 | 163.0 | 434.0 | RB1 |
| Hgene | PRMT2 | chr21:48068531 | chr4:4473433 | ENST00000397637 | + | 5 | 11 | 83_207 | 163.0 | 434.0 | RB1 |
| Hgene | PRMT2 | chr21:48068531 | chr4:4473433 | ENST00000397638 | + | 5 | 11 | 83_207 | 163.0 | 434.0 | RB1 |
| Hgene | PRMT2 | chr21:48068531 | chr4:4473433 | ENST00000440086 | + | 5 | 9 | 83_207 | 163.0 | 332.0 | RB1 |
| - Retained PPIs, but lost function due to frame-shift fusion. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Interaction lost with |
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Related Drugs for PRMT2-STX18 |
| Drugs targeting genes involved in this fusion gene. (DrugBank Version 5.1.8 2021-05-08) |
| Partner | Gene | UniProtAcc | DrugBank ID | Drug name | Drug activity | Drug type | Drug status |
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Related Diseases for PRMT2-STX18 |
| Diseases associated with fusion partners. (DisGeNet 4.0) |
| Partner | Gene | Disease ID | Disease name | # pubmeds | Source |
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