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Center for Computational Systems Medicine
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Fusion Gene Summary

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Fusion Gene ORF analysis

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Fusion Genomic Features

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Fusion Protein Features

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Fusion Gene Sequence

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Fusion Gene PPI analysis

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Related Drugs

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Related Diseases

Fusion gene:PRMT7-WWOX (FusionGDB2 ID:68942)

Fusion Gene Summary for PRMT7-WWOX

check button Fusion gene summary
Fusion gene informationFusion gene name: PRMT7-WWOX
Fusion gene ID: 68942
HgeneTgene
Gene symbol

PRMT7

WWOX

Gene ID

54496

51741

Gene nameprotein arginine methyltransferase 7WW domain containing oxidoreductase
SynonymsSBIDDSD16S432E|EIEE28|FOR|FRA16D|HHCMA56|PRO0128|SCAR12|SDR41C1|WOX1
Cytomap

16q22.1

16q23.1-q23.2

Type of geneprotein-codingprotein-coding
Descriptionprotein arginine N-methyltransferase 7[Myelin basic protein]-arginine N-methyltransferase PRMT7histone-arginine N-methyltransferase PRMT7WW domain-containing oxidoreductaseWW domain-containing protein WWOXfragile site FRA16D oxidoreductaseshort chain dehydrogenase/reductase family 41C member 1
Modification date2020032020200313
UniProtAcc..
Ensembl transtripts involved in fusion geneENST00000339507, ENST00000348497, 
ENST00000441236, ENST00000449359, 
ENST00000564441, 		ENST00000355860, 
ENST00000402655, ENST00000406884, 
ENST00000408984, ENST00000539474, 
ENST00000565791, ENST00000569818, 
ENST00000566780, 
Fusion gene scores* DoF score4 X 5 X 4=8030 X 23 X 10=6900
# samples 436
** MAII scorelog2(4/80*10)=-1
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0		log2(36/6900*10)=-4.26052755022322
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0
Context

PubMed: PRMT7 [Title/Abstract] AND WWOX [Title/Abstract] AND fusion [Title/Abstract]

Most frequent breakpointPRMT7(68382334)-WWOX(78420757), # samples:1
PRMT7(68380183)-WWOX(78420757), # samples:1
Anticipated loss of major functional domain due to fusion event.
* DoF score (Degree of Frequency) = # partners X # break points X # cancer types
** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10)

check button Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez
PartnerGeneGO IDGO termPubMed ID
HgenePRMT7

GO:0016571

histone methylation

15494416

HgenePRMT7

GO:0018216

peptidyl-arginine methylation

15044439

TgeneWWOX

GO:0030178

negative regulation of Wnt signaling pathway

19465938

TgeneWWOX

GO:0071560

cellular response to transforming growth factor beta stimulus

19366691


check buttonFusion gene breakpoints across PRMT7 (5'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.
all structure

check buttonFusion gene breakpoints across WWOX (3'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.
all structure

check button Fusion gene information from two resources (ChiTars 5.0 and ChimerDB 4.0)
* All genome coordinats were lifted-over on hg19.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
SourceDiseaseSampleHgeneHchrHbpHstrandTgeneTchrTbpTstrand
ChimerDB4STADTCGA-BR-A4QI-01APRMT7chr16

68380183

+WWOXchr16

78420757

+
ChimerDB4STADTCGA-BR-A4QI-01APRMT7chr16

68382334

+WWOXchr16

78420757

+


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Fusion Gene ORF analysis for PRMT7-WWOX

check button Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
ORFHenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrand
5CDS-intronENST00000339507ENST00000355860PRMT7chr16

68380183

+WWOXchr16

78420757

+
5CDS-intronENST00000339507ENST00000355860PRMT7chr16

68382334

+WWOXchr16

78420757

+
5CDS-intronENST00000339507ENST00000402655PRMT7chr16

68380183

+WWOXchr16

78420757

+
5CDS-intronENST00000339507ENST00000402655PRMT7chr16

68382334

+WWOXchr16

78420757

+
5CDS-intronENST00000339507ENST00000406884PRMT7chr16

68380183

+WWOXchr16

78420757

+
5CDS-intronENST00000339507ENST00000406884PRMT7chr16

68382334

+WWOXchr16

78420757

+
5CDS-intronENST00000339507ENST00000408984PRMT7chr16

68380183

+WWOXchr16

78420757

+
5CDS-intronENST00000339507ENST00000408984PRMT7chr16

68382334

+WWOXchr16

78420757

+
5CDS-intronENST00000339507ENST00000539474PRMT7chr16

68380183

+WWOXchr16

78420757

+
5CDS-intronENST00000339507ENST00000539474PRMT7chr16

68382334

+WWOXchr16

78420757

+
5CDS-intronENST00000339507ENST00000565791PRMT7chr16

68380183

+WWOXchr16

78420757

+
5CDS-intronENST00000339507ENST00000565791PRMT7chr16

68382334

+WWOXchr16

78420757

+
5CDS-intronENST00000339507ENST00000569818PRMT7chr16

68380183

+WWOXchr16

78420757

+
5CDS-intronENST00000339507ENST00000569818PRMT7chr16

68382334

+WWOXchr16

78420757

+
5CDS-intronENST00000348497ENST00000355860PRMT7chr16

68380183

+WWOXchr16

78420757

+
5CDS-intronENST00000348497ENST00000402655PRMT7chr16

68380183

+WWOXchr16

78420757

+
5CDS-intronENST00000348497ENST00000406884PRMT7chr16

68380183

+WWOXchr16

78420757

+
5CDS-intronENST00000348497ENST00000408984PRMT7chr16

68380183

+WWOXchr16

78420757

+
5CDS-intronENST00000348497ENST00000539474PRMT7chr16

68380183

+WWOXchr16

78420757

+
5CDS-intronENST00000348497ENST00000565791PRMT7chr16

68380183

+WWOXchr16

78420757

+
5CDS-intronENST00000348497ENST00000569818PRMT7chr16

68380183

+WWOXchr16

78420757

+
5CDS-intronENST00000441236ENST00000355860PRMT7chr16

68380183

+WWOXchr16

78420757

+
5CDS-intronENST00000441236ENST00000355860PRMT7chr16

68382334

+WWOXchr16

78420757

+
5CDS-intronENST00000441236ENST00000402655PRMT7chr16

68380183

+WWOXchr16

78420757

+
5CDS-intronENST00000441236ENST00000402655PRMT7chr16

68382334

+WWOXchr16

78420757

+
5CDS-intronENST00000441236ENST00000406884PRMT7chr16

68380183

+WWOXchr16

78420757

+
5CDS-intronENST00000441236ENST00000406884PRMT7chr16

68382334

+WWOXchr16

78420757

+
5CDS-intronENST00000441236ENST00000408984PRMT7chr16

68380183

+WWOXchr16

78420757

+
5CDS-intronENST00000441236ENST00000408984PRMT7chr16

68382334

+WWOXchr16

78420757

+
5CDS-intronENST00000441236ENST00000539474PRMT7chr16

68380183

+WWOXchr16

78420757

+
5CDS-intronENST00000441236ENST00000539474PRMT7chr16

68382334

+WWOXchr16

78420757

+
5CDS-intronENST00000441236ENST00000565791PRMT7chr16

68380183

+WWOXchr16

78420757

+
5CDS-intronENST00000441236ENST00000565791PRMT7chr16

68382334

+WWOXchr16

78420757

+
5CDS-intronENST00000441236ENST00000569818PRMT7chr16

68380183

+WWOXchr16

78420757

+
5CDS-intronENST00000441236ENST00000569818PRMT7chr16

68382334

+WWOXchr16

78420757

+
5CDS-intronENST00000449359ENST00000355860PRMT7chr16

68380183

+WWOXchr16

78420757

+
5CDS-intronENST00000449359ENST00000355860PRMT7chr16

68382334

+WWOXchr16

78420757

+
5CDS-intronENST00000449359ENST00000402655PRMT7chr16

68380183

+WWOXchr16

78420757

+
5CDS-intronENST00000449359ENST00000402655PRMT7chr16

68382334

+WWOXchr16

78420757

+
5CDS-intronENST00000449359ENST00000406884PRMT7chr16

68380183

+WWOXchr16

78420757

+
5CDS-intronENST00000449359ENST00000406884PRMT7chr16

68382334

+WWOXchr16

78420757

+
5CDS-intronENST00000449359ENST00000408984PRMT7chr16

68380183

+WWOXchr16

78420757

+
5CDS-intronENST00000449359ENST00000408984PRMT7chr16

68382334

+WWOXchr16

78420757

+
5CDS-intronENST00000449359ENST00000539474PRMT7chr16

68380183

+WWOXchr16

78420757

+
5CDS-intronENST00000449359ENST00000539474PRMT7chr16

68382334

+WWOXchr16

78420757

+
5CDS-intronENST00000449359ENST00000565791PRMT7chr16

68380183

+WWOXchr16

78420757

+
5CDS-intronENST00000449359ENST00000565791PRMT7chr16

68382334

+WWOXchr16

78420757

+
5CDS-intronENST00000449359ENST00000569818PRMT7chr16

68380183

+WWOXchr16

78420757

+
5CDS-intronENST00000449359ENST00000569818PRMT7chr16

68382334

+WWOXchr16

78420757

+
In-frameENST00000339507ENST00000566780PRMT7chr16

68380183

+WWOXchr16

78420757

+
In-frameENST00000339507ENST00000566780PRMT7chr16

68382334

+WWOXchr16

78420757

+
In-frameENST00000348497ENST00000566780PRMT7chr16

68380183

+WWOXchr16

78420757

+
In-frameENST00000441236ENST00000566780PRMT7chr16

68380183

+WWOXchr16

78420757

+
In-frameENST00000441236ENST00000566780PRMT7chr16

68382334

+WWOXchr16

78420757

+
In-frameENST00000449359ENST00000566780PRMT7chr16

68380183

+WWOXchr16

78420757

+
In-frameENST00000449359ENST00000566780PRMT7chr16

68382334

+WWOXchr16

78420757

+
intron-3CDSENST00000348497ENST00000566780PRMT7chr16

68382334

+WWOXchr16

78420757

+
intron-3CDSENST00000564441ENST00000566780PRMT7chr16

68380183

+WWOXchr16

78420757

+
intron-3CDSENST00000564441ENST00000566780PRMT7chr16

68382334

+WWOXchr16

78420757

+
intron-intronENST00000348497ENST00000355860PRMT7chr16

68382334

+WWOXchr16

78420757

+
intron-intronENST00000348497ENST00000402655PRMT7chr16

68382334

+WWOXchr16

78420757

+
intron-intronENST00000348497ENST00000406884PRMT7chr16

68382334

+WWOXchr16

78420757

+
intron-intronENST00000348497ENST00000408984PRMT7chr16

68382334

+WWOXchr16

78420757

+
intron-intronENST00000348497ENST00000539474PRMT7chr16

68382334

+WWOXchr16

78420757

+
intron-intronENST00000348497ENST00000565791PRMT7chr16

68382334

+WWOXchr16

78420757

+
intron-intronENST00000348497ENST00000569818PRMT7chr16

68382334

+WWOXchr16

78420757

+
intron-intronENST00000564441ENST00000355860PRMT7chr16

68380183

+WWOXchr16

78420757

+
intron-intronENST00000564441ENST00000355860PRMT7chr16

68382334

+WWOXchr16

78420757

+
intron-intronENST00000564441ENST00000402655PRMT7chr16

68380183

+WWOXchr16

78420757

+
intron-intronENST00000564441ENST00000402655PRMT7chr16

68382334

+WWOXchr16

78420757

+
intron-intronENST00000564441ENST00000406884PRMT7chr16

68380183

+WWOXchr16

78420757

+
intron-intronENST00000564441ENST00000406884PRMT7chr16

68382334

+WWOXchr16

78420757

+
intron-intronENST00000564441ENST00000408984PRMT7chr16

68380183

+WWOXchr16

78420757

+
intron-intronENST00000564441ENST00000408984PRMT7chr16

68382334

+WWOXchr16

78420757

+
intron-intronENST00000564441ENST00000539474PRMT7chr16

68380183

+WWOXchr16

78420757

+
intron-intronENST00000564441ENST00000539474PRMT7chr16

68382334

+WWOXchr16

78420757

+
intron-intronENST00000564441ENST00000565791PRMT7chr16

68380183

+WWOXchr16

78420757

+
intron-intronENST00000564441ENST00000565791PRMT7chr16

68382334

+WWOXchr16

78420757

+
intron-intronENST00000564441ENST00000569818PRMT7chr16

68380183

+WWOXchr16

78420757

+
intron-intronENST00000564441ENST00000569818PRMT7chr16

68382334

+WWOXchr16

78420757

+

check buttonORFfinder result based on the fusion transcript sequence of in-frame fusion genes.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandSeq length
(transcript)		BP loci
(transcript)		Predicted start
(transcript)		Predicted stop
(transcript)		Seq length
(amino acids)
ENST00000449359PRMT7chr1668382334+ENST00000566780WWOXchr1678420757+29901390612118685
ENST00000441236PRMT7chr1668382334+ENST00000566780WWOXchr1678420757+369520957662823685
ENST00000339507PRMT7chr1668382334+ENST00000566780WWOXchr1678420757+384322437642971735
ENST00000449359PRMT7chr1668380183+ENST00000566780WWOXchr1678420757+27681168611896611
ENST00000441236PRMT7chr1668380183+ENST00000566780WWOXchr1678420757+347318737662601611
ENST00000348497PRMT7chr1668380183+ENST00000566780WWOXchr1678420757+340118017662529587
ENST00000339507PRMT7chr1668380183+ENST00000566780WWOXchr1678420757+362120217642749661

check buttonDeepORF prediction of the coding potential based on the fusion transcript sequence of in-frame fusion genes. DeepORF is a coding potential classifier based on convolutional neural network by comparing the real Ribo-seq data. If the no-coding score < 0.5 and coding score > 0.5, then the in-frame fusion transcript is predicted as being likely translated.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandNo-coding scoreCoding score
ENST00000449359ENST00000566780PRMT7chr1668382334+WWOXchr1678420757+0.0058761440.9941239
ENST00000441236ENST00000566780PRMT7chr1668382334+WWOXchr1678420757+0.0061400510.9938599
ENST00000339507ENST00000566780PRMT7chr1668382334+WWOXchr1678420757+0.0055887490.9944113
ENST00000449359ENST00000566780PRMT7chr1668380183+WWOXchr1678420757+0.0079011630.9920988
ENST00000441236ENST00000566780PRMT7chr1668380183+WWOXchr1678420757+0.008298930.99170107
ENST00000348497ENST00000566780PRMT7chr1668380183+WWOXchr1678420757+0.0079081590.9920919
ENST00000339507ENST00000566780PRMT7chr1668380183+WWOXchr1678420757+0.0076674020.9923326

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Fusion Genomic Features for PRMT7-WWOX


check buttonFusionAI prediction of the potential fusion gene breakpoint based on the pre-mature RNA sequence context (+/- 5kb of individual partner genes, total 20kb length sequence). FusionAI is a fusion gene breakpoint classifier based on convolutional neural network by comparing the fusion positive and negative sequence context of ~ 20K fusion gene data. From here, we can have the relative potentency of the 20K genomic sequence how individual sequnce will be likely used as the gene fusion breakpoints.
HgeneHchrHbpHstrandTgeneTchrTbpTstrand1-pp (fusion gene breakpoint)
PRMT7chr1668382334+WWOXchr1678420756+0.0043118750.99568814
PRMT7chr1668380183+WWOXchr1678420756+5.06E-050.99994946
PRMT7chr1668382334+WWOXchr1678420756+0.0043118750.99568814
PRMT7chr1668380183+WWOXchr1678420756+5.06E-050.99994946

check buttonDistribution of 44 human genomic features loci across 20kb length fusion breakpoint regions. We integrated a total of 44 different types of human genomic feature loci information across five big categories including virus integration sites, repeats, structural variants, chromatin states, and gene expression regulation. More details are in help page.
genomic feature

check buttonDistribution of 44 human genomic features loci across 20kb length fusion breakpoint regions that are ovelapped with the top 1% feature importance score regions. More details are in help page.
genomic feature of top 1%

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Fusion Protein Features for PRMT7-WWOX


check button Four levels of functional features of fusion genes
Go to FGviewer search page for the most frequent breakpoint (https://ccsmweb.uth.edu/FGviewer/chr16:68382334/chr16:78420757)
- FGviewer provides the online visualization of the retention search of the protein functional features across DNA, RNA, protein, and pathological levels.
- How to search
1. Put your fusion gene symbol.
2. Press the tab key until there will be shown the breakpoint information filled.
4. Go down and press 'Search' tab twice.
4. Go down to have the hyperlink of the search result.
5. Click the hyperlink.
6. See the FGviewer result for your fusion gene.
FGviewer

check buttonMain function of each fusion partner protein. (from UniProt)
HgeneTgene
..
FUNCTION: Transcriptional activator which is required for calcium-dependent dendritic growth and branching in cortical neurons. Recruits CREB-binding protein (CREBBP) to nuclear bodies. Component of the CREST-BRG1 complex, a multiprotein complex that regulates promoter activation by orchestrating a calcium-dependent release of a repressor complex and a recruitment of an activator complex. In resting neurons, transcription of the c-FOS promoter is inhibited by BRG1-dependent recruitment of a phospho-RB1-HDAC1 repressor complex. Upon calcium influx, RB1 is dephosphorylated by calcineurin, which leads to release of the repressor complex. At the same time, there is increased recruitment of CREBBP to the promoter by a CREST-dependent mechanism, which leads to transcriptional activation. The CREST-BRG1 complex also binds to the NR2B promoter, and activity-dependent induction of NR2B expression involves a release of HDAC1 and recruitment of CREBBP (By similarity). {ECO:0000250}.FUNCTION: Transcriptional activator which is required for calcium-dependent dendritic growth and branching in cortical neurons. Recruits CREB-binding protein (CREBBP) to nuclear bodies. Component of the CREST-BRG1 complex, a multiprotein complex that regulates promoter activation by orchestrating a calcium-dependent release of a repressor complex and a recruitment of an activator complex. In resting neurons, transcription of the c-FOS promoter is inhibited by BRG1-dependent recruitment of a phospho-RB1-HDAC1 repressor complex. Upon calcium influx, RB1 is dephosphorylated by calcineurin, which leads to release of the repressor complex. At the same time, there is increased recruitment of CREBBP to the promoter by a CREST-dependent mechanism, which leads to transcriptional activation. The CREST-BRG1 complex also binds to the NR2B promoter, and activity-dependent induction of NR2B expression involves a release of HDAC1 and recruitment of CREBBP (By similarity). {ECO:0000250}.

check buttonRetention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at

download page


* Minus value of BPloci means that the break pointn is located before the CDS.
- In-frame and retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
HgenePRMT7chr16:68380183chr16:78420757ENST00000339507+111914_345397693.0DomainSAM-dependent MTase PRMT-type 1
HgenePRMT7chr16:68380183chr16:78420757ENST00000441236+101814_345347643.0DomainSAM-dependent MTase PRMT-type 1
HgenePRMT7chr16:68380183chr16:78420757ENST00000449359+91714_345347643.0DomainSAM-dependent MTase PRMT-type 1
HgenePRMT7chr16:68382334chr16:78420757ENST00000339507+141914_345471693.0DomainSAM-dependent MTase PRMT-type 1
HgenePRMT7chr16:68382334chr16:78420757ENST00000441236+131814_345421643.0DomainSAM-dependent MTase PRMT-type 1
HgenePRMT7chr16:68382334chr16:78420757ENST00000449359+121714_345421643.0DomainSAM-dependent MTase PRMT-type 1
TgeneWWOXchr16:68380183chr16:78420757ENST000003558600616_490190.0DomainWW 1
TgeneWWOXchr16:68380183chr16:78420757ENST000003558600657_900190.0DomainWW 2
TgeneWWOXchr16:68380183chr16:78420757ENST000004026550516_490312.0DomainWW 1
TgeneWWOXchr16:68380183chr16:78420757ENST000004026550557_900312.0DomainWW 2
TgeneWWOXchr16:68380183chr16:78420757ENST000004068840616_490235.0DomainWW 1
TgeneWWOXchr16:68380183chr16:78420757ENST000004068840657_900235.0DomainWW 2
TgeneWWOXchr16:68380183chr16:78420757ENST000005698180116_49037.0DomainWW 1
TgeneWWOXchr16:68380183chr16:78420757ENST000005698180157_90037.0DomainWW 2
TgeneWWOXchr16:68382334chr16:78420757ENST000003558600616_490190.0DomainWW 1
TgeneWWOXchr16:68382334chr16:78420757ENST000003558600657_900190.0DomainWW 2
TgeneWWOXchr16:68382334chr16:78420757ENST000004026550516_490312.0DomainWW 1
TgeneWWOXchr16:68382334chr16:78420757ENST000004026550557_900312.0DomainWW 2
TgeneWWOXchr16:68382334chr16:78420757ENST000004068840616_490235.0DomainWW 1
TgeneWWOXchr16:68382334chr16:78420757ENST000004068840657_900235.0DomainWW 2
TgeneWWOXchr16:68382334chr16:78420757ENST000005698180116_49037.0DomainWW 1
TgeneWWOXchr16:68382334chr16:78420757ENST000005698180157_90037.0DomainWW 2
TgeneWWOXchr16:68380183chr16:78420757ENST000003558600650_550190.0MotifNuclear localization signal
TgeneWWOXchr16:68380183chr16:78420757ENST000004026550550_550312.0MotifNuclear localization signal
TgeneWWOXchr16:68380183chr16:78420757ENST000004068840650_550235.0MotifNuclear localization signal
TgeneWWOXchr16:68380183chr16:78420757ENST000005698180150_55037.0MotifNuclear localization signal
TgeneWWOXchr16:68382334chr16:78420757ENST000003558600650_550190.0MotifNuclear localization signal
TgeneWWOXchr16:68382334chr16:78420757ENST000004026550550_550312.0MotifNuclear localization signal
TgeneWWOXchr16:68382334chr16:78420757ENST000004068840650_550235.0MotifNuclear localization signal
TgeneWWOXchr16:68382334chr16:78420757ENST000005698180150_55037.0MotifNuclear localization signal
TgeneWWOXchr16:68380183chr16:78420757ENST0000035586006131_1370190.0Nucleotide bindingNADP
TgeneWWOXchr16:68380183chr16:78420757ENST0000040265505131_1370312.0Nucleotide bindingNADP
TgeneWWOXchr16:68380183chr16:78420757ENST0000040688406131_1370235.0Nucleotide bindingNADP
TgeneWWOXchr16:68380183chr16:78420757ENST0000056981801131_137037.0Nucleotide bindingNADP
TgeneWWOXchr16:68382334chr16:78420757ENST0000035586006131_1370190.0Nucleotide bindingNADP
TgeneWWOXchr16:68382334chr16:78420757ENST0000040265505131_1370312.0Nucleotide bindingNADP
TgeneWWOXchr16:68382334chr16:78420757ENST0000040688406131_1370235.0Nucleotide bindingNADP
TgeneWWOXchr16:68382334chr16:78420757ENST0000056981801131_137037.0Nucleotide bindingNADP
TgeneWWOXchr16:68380183chr16:78420757ENST0000035586006209_2730190.0RegionMediates targeting to the mitochondria
TgeneWWOXchr16:68380183chr16:78420757ENST0000040265505209_2730312.0RegionMediates targeting to the mitochondria
TgeneWWOXchr16:68380183chr16:78420757ENST0000040688406209_2730235.0RegionMediates targeting to the mitochondria
TgeneWWOXchr16:68380183chr16:78420757ENST00000408984410209_273172311.6666666666667RegionMediates targeting to the mitochondria
TgeneWWOXchr16:68380183chr16:78420757ENST0000056678049209_273172415.0RegionMediates targeting to the mitochondria
TgeneWWOXchr16:68380183chr16:78420757ENST0000056981801209_273037.0RegionMediates targeting to the mitochondria
TgeneWWOXchr16:68382334chr16:78420757ENST0000035586006209_2730190.0RegionMediates targeting to the mitochondria
TgeneWWOXchr16:68382334chr16:78420757ENST0000040265505209_2730312.0RegionMediates targeting to the mitochondria
TgeneWWOXchr16:68382334chr16:78420757ENST0000040688406209_2730235.0RegionMediates targeting to the mitochondria
TgeneWWOXchr16:68382334chr16:78420757ENST00000408984410209_273172311.6666666666667RegionMediates targeting to the mitochondria
TgeneWWOXchr16:68382334chr16:78420757ENST0000056678049209_273172415.0RegionMediates targeting to the mitochondria
TgeneWWOXchr16:68382334chr16:78420757ENST0000056981801209_273037.0RegionMediates targeting to the mitochondria

- In-frame and not-retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
HgenePRMT7chr16:68380183chr16:78420757ENST00000339507+1119358_684397693.0DomainSAM-dependent MTase PRMT-type 2
HgenePRMT7chr16:68380183chr16:78420757ENST00000348497+91414_345323545.0DomainSAM-dependent MTase PRMT-type 1
HgenePRMT7chr16:68380183chr16:78420757ENST00000348497+914358_684323545.0DomainSAM-dependent MTase PRMT-type 2
HgenePRMT7chr16:68380183chr16:78420757ENST00000441236+1018358_684347643.0DomainSAM-dependent MTase PRMT-type 2
HgenePRMT7chr16:68380183chr16:78420757ENST00000449359+917358_684347643.0DomainSAM-dependent MTase PRMT-type 2
HgenePRMT7chr16:68382334chr16:78420757ENST00000339507+1419358_684471693.0DomainSAM-dependent MTase PRMT-type 2
HgenePRMT7chr16:68382334chr16:78420757ENST00000348497+11414_3450545.0DomainSAM-dependent MTase PRMT-type 1
HgenePRMT7chr16:68382334chr16:78420757ENST00000348497+114358_6840545.0DomainSAM-dependent MTase PRMT-type 2
HgenePRMT7chr16:68382334chr16:78420757ENST00000441236+1318358_684421643.0DomainSAM-dependent MTase PRMT-type 2
HgenePRMT7chr16:68382334chr16:78420757ENST00000449359+1217358_684421643.0DomainSAM-dependent MTase PRMT-type 2
TgeneWWOXchr16:68380183chr16:78420757ENST0000040898441016_49172311.6666666666667DomainWW 1
TgeneWWOXchr16:68380183chr16:78420757ENST0000040898441057_90172311.6666666666667DomainWW 2
TgeneWWOXchr16:68380183chr16:78420757ENST000005667804916_49172415.0DomainWW 1
TgeneWWOXchr16:68380183chr16:78420757ENST000005667804957_90172415.0DomainWW 2
TgeneWWOXchr16:68382334chr16:78420757ENST0000040898441016_49172311.6666666666667DomainWW 1
TgeneWWOXchr16:68382334chr16:78420757ENST0000040898441057_90172311.6666666666667DomainWW 2
TgeneWWOXchr16:68382334chr16:78420757ENST000005667804916_49172415.0DomainWW 1
TgeneWWOXchr16:68382334chr16:78420757ENST000005667804957_90172415.0DomainWW 2
TgeneWWOXchr16:68380183chr16:78420757ENST0000040898441050_55172311.6666666666667MotifNuclear localization signal
TgeneWWOXchr16:68380183chr16:78420757ENST000005667804950_55172415.0MotifNuclear localization signal
TgeneWWOXchr16:68382334chr16:78420757ENST0000040898441050_55172311.6666666666667MotifNuclear localization signal
TgeneWWOXchr16:68382334chr16:78420757ENST000005667804950_55172415.0MotifNuclear localization signal
TgeneWWOXchr16:68380183chr16:78420757ENST00000408984410131_137172311.6666666666667Nucleotide bindingNADP
TgeneWWOXchr16:68380183chr16:78420757ENST0000056678049131_137172415.0Nucleotide bindingNADP
TgeneWWOXchr16:68382334chr16:78420757ENST00000408984410131_137172311.6666666666667Nucleotide bindingNADP
TgeneWWOXchr16:68382334chr16:78420757ENST0000056678049131_137172415.0Nucleotide bindingNADP


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Fusion Gene Sequence for PRMT7-WWOX


check button For in-frame fusion transcripts, we provide the fusion transcript sequences and fusion amino acid sequences. To have fusion amino acid sequence, we ran ORFfinder and chose the longest ORF among the all predicted ones.
>68942_68942_1_PRMT7-WWOX_PRMT7_chr16_68380183_ENST00000339507_WWOX_chr16_78420757_ENST00000566780_length(transcript)=3621nt_BP=2021nt
CTTTGGGGTTCTGTGTGCAGCGAGCATGGTGTCCTTGGCACCAGGGTTTCGGCAGAGGAGCCTAGCGTGGGCCTACTTGGACTCCTCCGC
GTGGGGCAGCTCGGGACACCCGGGCCTGCAGGAGAGCGGGGTTCTAGGCTGGCCCCGGCTCTGCAGTGCAGCCGGGTGCCTGCCACTCGC
GGGGCTCTGTCGCAGTACTCGTGCCTGGCGCCTCCCCTCAGCCACAGAGACCGCAGTAGCTCCAACCATCGCACCCCTAACTGGGCCACG
AGTTCTCTGATTGCCAGACCTGTTGTCTTTGCCACTCACTGTTCTGAGTAATTGGAGAGTCGTGTATTCACTACACGCCAACCAGAGTGG
TCCTGTAAAAGCGTAAGCCTAGTGTAGATACGCTTCTGCTTAAAACTCTTGAGTGGCTCCCAGTGCTTTTAGAACAAAATCCAAACGCCT
TTCCGAAGTCGACAAGGCCCAGCTTGATTGAGCAGAAGATGTGATAGGAGATGAGGAGCGGGGGGCTTCTGCAAAAGTGCTTCGGTCGCT
CAGGCTTTTGGCACATTTTGCTTATGCAACCTAGTTCTTTCTACCTTAGGGCCTTTTCTTGGGAAAGTTGGGAGTCTCACTCTGCTGCCT
AGGCTGAGTGCAGTGGTGTGATCGAGGCGCACTGCAGCCTTGACCTCCTGGGCTCAAGCGATCCTCACCTCGGCCTACCGAGTAGCTGGG
ACTACAGGCACGCGCCACTACACTCGGATTTCTGACAGTCAGACTTGTCCACAAGAACTCAACTGGCAAGGCTGCTTTTCTGTGCTAAAA
CTGGGGAGCTAGTGGGCACCATGAAGATCTTCTGCAGTCGGGCCAATCCGACCACGGGGTCTGTGGAGTGGCTGGAGGAGGATGAACACT
ATGATTACCACCAGGAGATTGCAAGGTCATCTTATGCAGATATGCTACATGACAAAGACAGAAATGTAAAATACTACCAAGGTATCCGGG
CTGCCGTGAGCAGGGTGAAGGACAGAGGACAGAAGGCCTTGGTTCTCGACATTGGCACTGGCACGGGACTCTTGTCAATGATGGCGGTCA
CAGCAGGTGCCGACTTCTGCTATGCCATCGAGGTTTTCAAGCCTATGGCTGATGCTGCTGTGAAGATTGTGGAGAAAAATGGCTTTAGTG
ATAAGATTAAGGTTATCAACAAGCATTCCACCGAGGTGACTGTAGGTCCAGAGGGTGACATGCCATGCCGTGCCAACATCCTGGTCACAG
AGTTGTTTGACACAGAGCTGATCGGGGAGGGGGCGCTGCCCTCCTATGAGCACGCACACAGGCATCTCGTGGAGGAAAATTGTGAGGCCG
TGCCCCACAGAGCCACCGTCTATGCACAGCTGGTGGAGTCCGGGAGGATGTGGTCGTGGAACAAGCTATTTCCCATCCACGTGCAGACCA
GCCTCGGAGAGCAGGTCATCGTCCCTCCCGTTGACGTGGAGAGCTGCCCTGGCGCACCCTCTGTCTGTGACATTCAGCTGAACCAGGTGT
CACCAGCCGACTTTACAGTCCTCAGCGATGTGCTGCCCATGTTCAGCATAGACTTCAGCAAGCAAGTCAGTAGCTCAGCAGCCTGCCATA
GCAGGCGGTTTGAACCTCTGACATCTGGCCGAGCTCAGGTGGTTCTCTCGTGGTGGGACATTGAAATGGACCCTGAGGGGAAGATCAAGT
GCACCATGGCCCCCTTCTGGGCACACTCAGACCCAGAGGAGATGCAGTGGCGGGACCACTGGATGCAGTGTGTGTACTTCCTGCCACAAG
AGGAGCCTGTGGTGCAGGGCTCAGCGCTCTATCTGGTAGCCCACCACGATGACTACTGCGTATGGTACAGCCTGCAGAGGACCAGCCCTG
AAAAGAATGAGAGAGTCCGCCAGATGCGCCCCGTGTGTGACTGCCAGGCTCACCTGCTCTGGAACCGGCCTCGGTTTGGAGAGATCAATG
ACCAGGACAGAACTGATCGATACGTCCAGGCTCTGAGGACCCATAAAGCCAAGGTAGAAGCAATGACCCTGGACCTCGCTCTGCTCCGTA
GCGTGCAGCATTTTGCTGAAGCATTCAAGGCCAAGAATGTGCCTCTTCATGTGCTTGTGTGCAACGCAGCAACTTTTGCTCTACCCTGGA
GTCTCACCAAAGATGGCCTGGAGACCACCTTTCAAGTGAATCATCTGGGGCACTTCTACCTTGTCCAGCTCCTCCAGGATGTTTTGTGCC
GCTCAGCTCCTGCCCGTGTCATTGTGGTCTCCTCAGAGTCCCATCGATTTACAGATATTAACGACTCCTTGGGAAAACTGGACTTCAGTC
GCCTCTCTCCAACAAAAAACGACTATTGGGCGATGCTGGCTTATAACAGGTCCAAGCTCTGCAACATCCTCTTCTCCAACGAGCTGCACC
GTCGCCTCTCCCCACGCGGGGTCACGTCGAACGCAGTGCATCCTGGAAATATGATGTACTCCAACATTCATCGCAGCTGGTGGGTGTACA
CACTGCTGTTTACCTTGGCGAGGCCTTTCACCAAGTCCATGCAACAGGGAGCTGCCACCACCGTGTACTGTGCTGCTGTCCCAGAACTGG
AGGGTCTGGGAGGGATGTACTTCAACAACTGCTGCCGCTGCATGCCCTCACCAGAAGCTCAGAGCGAAGAGACGGCCCGGACCCTGTGGG
CGCTCAGCGAGAGGCTGATCCAAGAACGGCTTGGCAGCCAGTCCGGCTAAGTGGAGCTCAGAGCGGATGGGCACACACACCCGCCCTGTG
TGTGTCCCCTCACGCAAGTGCCAGGGCTGGGCCCCTTCCAAATGTCCCTCCAACACAGATCCGCAAGAGTAAAGGAAATAAGAGCAGTCA
CAACAGAGTGAAAAATCTTAAGTACCAATGGGAAGCAGGGAATTCCTGGGGTAAAGTATCACTTTTCTGGGGCTGGGCTAGGCATAGGTC
TCTTTGCTTTCTGGTGGTGGCCTGTTTGAAAGTAAAAACCTGCTTGGTGTGTAGGTTCCGTATCTCCCTGGAGAAGCACCAGCAATTCTC
TTTCTTTTACTGTTATAGAATAGCCTGAGGTCCCCTCGTCCCATCCAGCTACCACCACGGCCACCACTGCAGCCGGGGGCTGGCCTTCTC
CTACTTAGGGAAGAAAAAGCAAGTGTTCACTGCTCCTTGCTGCATTGATCCAGGAGATAATTGTTTCATTCATCCTGACCAAGACTGAGC
CAGCTTAGCAACTGCTGGGGAGACAAATCTCAGAACCTTGTCCCAGCCAGTGAGGATGACAGTGACACCCAGAGGGAGTAGAATACGCAG
AACTACCAGGTGGCAAAGTACTTGTCATAGACTCCTTTGCTAATGCTATGCAAAAAATTCTTTAGAGATTATAACAAATTTTTCAAATCA
TTCCTTAGATACCTTGAAAGGCAGGAAGGGAAGCGTATATACTTAAGAATACACAGGATATTTTGGGGGGCAGAGAATAAAACGTTAGTT
AATCCCTTTGTCTGTCAATCACAGTCTCAGTTCTCTTGCTTTCACATTGTACTTAAACCTCCTGCTGTGCCTCGCATCCTATGCTTAATA

>68942_68942_1_PRMT7-WWOX_PRMT7_chr16_68380183_ENST00000339507_WWOX_chr16_78420757_ENST00000566780_length(amino acids)=661AA_BP=419
MSTRTQLARLLFCAKTGELVGTMKIFCSRANPTTGSVEWLEEDEHYDYHQEIARSSYADMLHDKDRNVKYYQGIRAAVSRVKDRGQKALV
LDIGTGTGLLSMMAVTAGADFCYAIEVFKPMADAAVKIVEKNGFSDKIKVINKHSTEVTVGPEGDMPCRANILVTELFDTELIGEGALPS
YEHAHRHLVEENCEAVPHRATVYAQLVESGRMWSWNKLFPIHVQTSLGEQVIVPPVDVESCPGAPSVCDIQLNQVSPADFTVLSDVLPMF
SIDFSKQVSSSAACHSRRFEPLTSGRAQVVLSWWDIEMDPEGKIKCTMAPFWAHSDPEEMQWRDHWMQCVYFLPQEEPVVQGSALYLVAH
HDDYCVWYSLQRTSPEKNERVRQMRPVCDCQAHLLWNRPRFGEINDQDRTDRYVQALRTHKAKVEAMTLDLALLRSVQHFAEAFKAKNVP
LHVLVCNAATFALPWSLTKDGLETTFQVNHLGHFYLVQLLQDVLCRSAPARVIVVSSESHRFTDINDSLGKLDFSRLSPTKNDYWAMLAY
NRSKLCNILFSNELHRRLSPRGVTSNAVHPGNMMYSNIHRSWWVYTLLFTLARPFTKSMQQGAATTVYCAAVPELEGLGGMYFNNCCRCM

--------------------------------------------------------------
>68942_68942_2_PRMT7-WWOX_PRMT7_chr16_68380183_ENST00000348497_WWOX_chr16_78420757_ENST00000566780_length(transcript)=3401nt_BP=1801nt
CGCTTTGGGGTTCTGTGTGCAGCGAGCATGGTGTCCTTGGCACCAGGGTTTCGGCAGAGGAGCCTAGCGTGGGCCTACTTGGACTCCTCC
GCGTGGGGCAGCTCGGGACACCCGGGCCTGCAGGAGAGCGGGGTTCTAGGCTGGCCCCGGCTCTGCAGTGCAGCCGGGTGCCTGCCACTC
GCGGGGCTCTGTCGCAGTACTCGTGCCTGGCGCCTCCCCTCAGCCACAGAGACCGCAGTAGCTCCAACCATCGCACCCCTAACTGGGCCA
CGAGTTCTCTGATTGCCAGACCTGTTGTCTTTGCCACTCACTGTTCTGAGTAATTGGAGAGTCGTGTATTCACTACACGCCAACCAGAGT
GGTCCTGTAAAAGCGTAAGCCTAGTGTAGATACGCTTCTGCTTAAAACTCTTGAGTGGCTCCCAGTGCTTTTAGAACAAAATCCAAACGC
CTTTCCGAAGTCGACAAGGCCCAGCTTGATTGAGCAGAAGATGTGATAGGAGATGAGGAGCGGGGGGCTTCTGCAAAAGTGCTTCGGTCG
CTCAGGCTTTTGGCACATTTTGCTTATGCAACCTAGTTCTTTCTACCTTAGGGCCTTTTCTTGGGAAAGTTGGGAGTCTCACTCTGCTGC
CTAGGCTGAGTGCAGTGGTGTGATCGAGGCGCACTGCAGCCTTGACCTCCTGGGCTCAAGCGATCCTCACCTCGGCCTACCGAGTAGCTG
GGACTACAGGCACGCGCCACTACACTCGGATTTCTGACAGTCAGACTTGTCCACAAGAACTCAACTGGCAAGGCTGCTTTTCTGTGCTAA
AACTGGGGAGCTAGTGGGCACCATGAAGATCTTCTGCAGTCGGGCCAATCCGACCACGGGGTCTGTGGAGTGGCTGGAGGAGGATGAACA
CTATGATTACCACCAGGAGATTGCAAGGTCATCTTATGCAGATATGCTACATGACAAAGACAGAAATGTAAAATACTACCAAGGTATCCG
GGCTGCCGTGAGCAGGGTGAAGGACAGAGGACAGAAGGCCTTGGTTCTCGACATTGGCACTGGCACGGGACTCTTGTCAATGATGGCGGT
CACAGCAGGTGCCGACTTCTGCTATGCCATCGAGGAAAATTGTGAGGCCGTGCCCCACAGAGCCACCGTCTATGCACAGCTGGTGGAGTC
CGGGAGGATGTGGTCGTGGAACAAGCTATTTCCCATCCACGTGCAGACCAGCCTCGGAGAGCAGGTCATCGTCCCTCCCGTTGACGTGGA
GAGCTGCCCTGGCGCACCCTCTGTCTGTGACATTCAGCTGAACCAGGTGTCACCAGCCGACTTTACAGTCCTCAGCGATGTGCTGCCCAT
GTTCAGCATAGACTTCAGCAAGCAAGTCAGTAGCTCAGCAGCCTGCCATAGCAGGCGGTTTGAACCTCTGACATCTGGCCGAGCTCAGGT
GGTTCTCTCGTGGTGGGACATTGAAATGGACCCTGAGGGGAAGATCAAGTGCACCATGGCCCCCTTCTGGGCACACTCAGACCCAGAGGA
GATGCAGTGGCGGGACCACTGGATGCAGTGTGTGTACTTCCTGCCACAAGAGGAGCCTGTGGTGCAGGGCTCAGCGCTCTATCTGGTAGC
CCACCACGATGACTACTGCGTATGGTACAGCCTGCAGAGGACCAGCCCTGAAAAGAATGAGAGAGTCCGCCAGATGCGCCCCGTGTGTGA
CTGCCAGGCTCACCTGCTCTGGAACCGGCCTCGGTTTGGAGAGATCAATGACCAGGACAGAACTGATCGATACGTCCAGGCTCTGAGGAC
CCATAAAGCCAAGGTAGAAGCAATGACCCTGGACCTCGCTCTGCTCCGTAGCGTGCAGCATTTTGCTGAAGCATTCAAGGCCAAGAATGT
GCCTCTTCATGTGCTTGTGTGCAACGCAGCAACTTTTGCTCTACCCTGGAGTCTCACCAAAGATGGCCTGGAGACCACCTTTCAAGTGAA
TCATCTGGGGCACTTCTACCTTGTCCAGCTCCTCCAGGATGTTTTGTGCCGCTCAGCTCCTGCCCGTGTCATTGTGGTCTCCTCAGAGTC
CCATCGATTTACAGATATTAACGACTCCTTGGGAAAACTGGACTTCAGTCGCCTCTCTCCAACAAAAAACGACTATTGGGCGATGCTGGC
TTATAACAGGTCCAAGCTCTGCAACATCCTCTTCTCCAACGAGCTGCACCGTCGCCTCTCCCCACGCGGGGTCACGTCGAACGCAGTGCA
TCCTGGAAATATGATGTACTCCAACATTCATCGCAGCTGGTGGGTGTACACACTGCTGTTTACCTTGGCGAGGCCTTTCACCAAGTCCAT
GCAACAGGGAGCTGCCACCACCGTGTACTGTGCTGCTGTCCCAGAACTGGAGGGTCTGGGAGGGATGTACTTCAACAACTGCTGCCGCTG
CATGCCCTCACCAGAAGCTCAGAGCGAAGAGACGGCCCGGACCCTGTGGGCGCTCAGCGAGAGGCTGATCCAAGAACGGCTTGGCAGCCA
GTCCGGCTAAGTGGAGCTCAGAGCGGATGGGCACACACACCCGCCCTGTGTGTGTCCCCTCACGCAAGTGCCAGGGCTGGGCCCCTTCCA
AATGTCCCTCCAACACAGATCCGCAAGAGTAAAGGAAATAAGAGCAGTCACAACAGAGTGAAAAATCTTAAGTACCAATGGGAAGCAGGG
AATTCCTGGGGTAAAGTATCACTTTTCTGGGGCTGGGCTAGGCATAGGTCTCTTTGCTTTCTGGTGGTGGCCTGTTTGAAAGTAAAAACC
TGCTTGGTGTGTAGGTTCCGTATCTCCCTGGAGAAGCACCAGCAATTCTCTTTCTTTTACTGTTATAGAATAGCCTGAGGTCCCCTCGTC
CCATCCAGCTACCACCACGGCCACCACTGCAGCCGGGGGCTGGCCTTCTCCTACTTAGGGAAGAAAAAGCAAGTGTTCACTGCTCCTTGC
TGCATTGATCCAGGAGATAATTGTTTCATTCATCCTGACCAAGACTGAGCCAGCTTAGCAACTGCTGGGGAGACAAATCTCAGAACCTTG
TCCCAGCCAGTGAGGATGACAGTGACACCCAGAGGGAGTAGAATACGCAGAACTACCAGGTGGCAAAGTACTTGTCATAGACTCCTTTGC
TAATGCTATGCAAAAAATTCTTTAGAGATTATAACAAATTTTTCAAATCATTCCTTAGATACCTTGAAAGGCAGGAAGGGAAGCGTATAT
ACTTAAGAATACACAGGATATTTTGGGGGGCAGAGAATAAAACGTTAGTTAATCCCTTTGTCTGTCAATCACAGTCTCAGTTCTCTTGCT

>68942_68942_2_PRMT7-WWOX_PRMT7_chr16_68380183_ENST00000348497_WWOX_chr16_78420757_ENST00000566780_length(amino acids)=587AA_BP=345
MSTRTQLARLLFCAKTGELVGTMKIFCSRANPTTGSVEWLEEDEHYDYHQEIARSSYADMLHDKDRNVKYYQGIRAAVSRVKDRGQKALV
LDIGTGTGLLSMMAVTAGADFCYAIEENCEAVPHRATVYAQLVESGRMWSWNKLFPIHVQTSLGEQVIVPPVDVESCPGAPSVCDIQLNQ
VSPADFTVLSDVLPMFSIDFSKQVSSSAACHSRRFEPLTSGRAQVVLSWWDIEMDPEGKIKCTMAPFWAHSDPEEMQWRDHWMQCVYFLP
QEEPVVQGSALYLVAHHDDYCVWYSLQRTSPEKNERVRQMRPVCDCQAHLLWNRPRFGEINDQDRTDRYVQALRTHKAKVEAMTLDLALL
RSVQHFAEAFKAKNVPLHVLVCNAATFALPWSLTKDGLETTFQVNHLGHFYLVQLLQDVLCRSAPARVIVVSSESHRFTDINDSLGKLDF
SRLSPTKNDYWAMLAYNRSKLCNILFSNELHRRLSPRGVTSNAVHPGNMMYSNIHRSWWVYTLLFTLARPFTKSMQQGAATTVYCAAVPE

--------------------------------------------------------------
>68942_68942_3_PRMT7-WWOX_PRMT7_chr16_68380183_ENST00000441236_WWOX_chr16_78420757_ENST00000566780_length(transcript)=3473nt_BP=1873nt
CGCTTTGGGGTTCTGTGTGCAGCGAGCATGGTGTCCTTGGCACCAGGGTTTCGGCAGAGGAGCCTAGCGTGGGCCTACTTGGACTCCTCC
GCGTGGGGCAGCTCGGGACACCCGGGCCTGCAGGAGAGCGGGGTTCTAGGCTGGCCCCGGCTCTGCAGTGCAGCCGGGTGCCTGCCACTC
GCGGGGCTCTGTCGCAGTACTCGTGCCTGGCGCCTCCCCTCAGCCACAGAGACCGCAGTAGCTCCAACCATCGCACCCCTAACTGGGCCA
CGAGTTCTCTGATTGCCAGACCTGTTGTCTTTGCCACTCACTGTTCTGAGTAATTGGAGAGTCGTGTATTCACTACACGCCAACCAGAGT
GGTCCTGTAAAAGCGTAAGCCTAGTGTAGATACGCTTCTGCTTAAAACTCTTGAGTGGCTCCCAGTGCTTTTAGAACAAAATCCAAACGC
CTTTCCGAAGTCGACAAGGCCCAGCTTGATTGAGCAGAAGATGTGATAGGAGATGAGGAGCGGGGGGCTTCTGCAAAAGTGCTTCGGTCG
CTCAGGCTTTTGGCACATTTTGCTTATGCAACCTAGTTCTTTCTACCTTAGGGCCTTTTCTTGGGAAAGTTGGGAGTCTCACTCTGCTGC
CTAGGCTGAGTGCAGTGGTGTGATCGAGGCGCACTGCAGCCTTGACCTCCTGGGCTCAAGCGATCCTCACCTCGGCCTACCGAGTAGCTG
GGACTACAGGCACGCGCCACTACACTCGGATTTCTGACAGTCAGACTTGTCCACAAGAACTCAACTGGCAAGGCTGCTTTTCTGTGCTAA
AACTGGGGAGCTAGTGGGCACCATGAAGATCTTCTGCAGTCGGGCCAATCCGACCACGGGGTCTGTGGAGTGGCTGGAGGAGGATGAACA
CTATGATTACCACCAGGAGATTGCAAGGTCATCTTATGCAGATATGCTACATGACAAAGACAGAGTTTTCAAGCCTATGGCTGATGCTGC
TGTGAAGATTGTGGAGAAAAATGGCTTTAGTGATAAGATTAAGGTTATCAACAAGCATTCCACCGAGGTGACTGTAGGTCCAGAGGGTGA
CATGCCATGCCGTGCCAACATCCTGGTCACAGAGTTGTTTGACACAGAGCTGATCGGGGAGGGGGCGCTGCCCTCCTATGAGCACGCACA
CAGGCATCTCGTGGAGGAAAATTGTGAGGCCGTGCCCCACAGAGCCACCGTCTATGCACAGCTGGTGGAGTCCGGGAGGATGTGGTCGTG
GAACAAGCTATTTCCCATCCACGTGCAGACCAGCCTCGGAGAGCAGGTCATCGTCCCTCCCGTTGACGTGGAGAGCTGCCCTGGCGCACC
CTCTGTCTGTGACATTCAGCTGAACCAGGTGTCACCAGCCGACTTTACAGTCCTCAGCGATGTGCTGCCCATGTTCAGCATAGACTTCAG
CAAGCAAGTCAGTAGCTCAGCAGCCTGCCATAGCAGGCGGTTTGAACCTCTGACATCTGGCCGAGCTCAGGTGGTTCTCTCGTGGTGGGA
CATTGAAATGGACCCTGAGGGGAAGATCAAGTGCACCATGGCCCCCTTCTGGGCACACTCAGACCCAGAGGAGATGCAGTGGCGGGACCA
CTGGATGCAGTGTGTGTACTTCCTGCCACAAGAGGAGCCTGTGGTGCAGGGCTCAGCGCTCTATCTGGTAGCCCACCACGATGACTACTG
CGTATGGTACAGCCTGCAGAGGACCAGCCCTGAAAAGAATGAGAGAGTCCGCCAGATGCGCCCCGTGTGTGACTGCCAGGCTCACCTGCT
CTGGAACCGGCCTCGGTTTGGAGAGATCAATGACCAGGACAGAACTGATCGATACGTCCAGGCTCTGAGGACCCATAAAGCCAAGGTAGA
AGCAATGACCCTGGACCTCGCTCTGCTCCGTAGCGTGCAGCATTTTGCTGAAGCATTCAAGGCCAAGAATGTGCCTCTTCATGTGCTTGT
GTGCAACGCAGCAACTTTTGCTCTACCCTGGAGTCTCACCAAAGATGGCCTGGAGACCACCTTTCAAGTGAATCATCTGGGGCACTTCTA
CCTTGTCCAGCTCCTCCAGGATGTTTTGTGCCGCTCAGCTCCTGCCCGTGTCATTGTGGTCTCCTCAGAGTCCCATCGATTTACAGATAT
TAACGACTCCTTGGGAAAACTGGACTTCAGTCGCCTCTCTCCAACAAAAAACGACTATTGGGCGATGCTGGCTTATAACAGGTCCAAGCT
CTGCAACATCCTCTTCTCCAACGAGCTGCACCGTCGCCTCTCCCCACGCGGGGTCACGTCGAACGCAGTGCATCCTGGAAATATGATGTA
CTCCAACATTCATCGCAGCTGGTGGGTGTACACACTGCTGTTTACCTTGGCGAGGCCTTTCACCAAGTCCATGCAACAGGGAGCTGCCAC
CACCGTGTACTGTGCTGCTGTCCCAGAACTGGAGGGTCTGGGAGGGATGTACTTCAACAACTGCTGCCGCTGCATGCCCTCACCAGAAGC
TCAGAGCGAAGAGACGGCCCGGACCCTGTGGGCGCTCAGCGAGAGGCTGATCCAAGAACGGCTTGGCAGCCAGTCCGGCTAAGTGGAGCT
CAGAGCGGATGGGCACACACACCCGCCCTGTGTGTGTCCCCTCACGCAAGTGCCAGGGCTGGGCCCCTTCCAAATGTCCCTCCAACACAG
ATCCGCAAGAGTAAAGGAAATAAGAGCAGTCACAACAGAGTGAAAAATCTTAAGTACCAATGGGAAGCAGGGAATTCCTGGGGTAAAGTA
TCACTTTTCTGGGGCTGGGCTAGGCATAGGTCTCTTTGCTTTCTGGTGGTGGCCTGTTTGAAAGTAAAAACCTGCTTGGTGTGTAGGTTC
CGTATCTCCCTGGAGAAGCACCAGCAATTCTCTTTCTTTTACTGTTATAGAATAGCCTGAGGTCCCCTCGTCCCATCCAGCTACCACCAC
GGCCACCACTGCAGCCGGGGGCTGGCCTTCTCCTACTTAGGGAAGAAAAAGCAAGTGTTCACTGCTCCTTGCTGCATTGATCCAGGAGAT
AATTGTTTCATTCATCCTGACCAAGACTGAGCCAGCTTAGCAACTGCTGGGGAGACAAATCTCAGAACCTTGTCCCAGCCAGTGAGGATG
ACAGTGACACCCAGAGGGAGTAGAATACGCAGAACTACCAGGTGGCAAAGTACTTGTCATAGACTCCTTTGCTAATGCTATGCAAAAAAT
TCTTTAGAGATTATAACAAATTTTTCAAATCATTCCTTAGATACCTTGAAAGGCAGGAAGGGAAGCGTATATACTTAAGAATACACAGGA
TATTTTGGGGGGCAGAGAATAAAACGTTAGTTAATCCCTTTGTCTGTCAATCACAGTCTCAGTTCTCTTGCTTTCACATTGTACTTAAAC

>68942_68942_3_PRMT7-WWOX_PRMT7_chr16_68380183_ENST00000441236_WWOX_chr16_78420757_ENST00000566780_length(amino acids)=611AA_BP=369
MSTRTQLARLLFCAKTGELVGTMKIFCSRANPTTGSVEWLEEDEHYDYHQEIARSSYADMLHDKDRVFKPMADAAVKIVEKNGFSDKIKV
INKHSTEVTVGPEGDMPCRANILVTELFDTELIGEGALPSYEHAHRHLVEENCEAVPHRATVYAQLVESGRMWSWNKLFPIHVQTSLGEQ
VIVPPVDVESCPGAPSVCDIQLNQVSPADFTVLSDVLPMFSIDFSKQVSSSAACHSRRFEPLTSGRAQVVLSWWDIEMDPEGKIKCTMAP
FWAHSDPEEMQWRDHWMQCVYFLPQEEPVVQGSALYLVAHHDDYCVWYSLQRTSPEKNERVRQMRPVCDCQAHLLWNRPRFGEINDQDRT
DRYVQALRTHKAKVEAMTLDLALLRSVQHFAEAFKAKNVPLHVLVCNAATFALPWSLTKDGLETTFQVNHLGHFYLVQLLQDVLCRSAPA
RVIVVSSESHRFTDINDSLGKLDFSRLSPTKNDYWAMLAYNRSKLCNILFSNELHRRLSPRGVTSNAVHPGNMMYSNIHRSWWVYTLLFT

--------------------------------------------------------------
>68942_68942_4_PRMT7-WWOX_PRMT7_chr16_68380183_ENST00000449359_WWOX_chr16_78420757_ENST00000566780_length(transcript)=2768nt_BP=1168nt
AAAAGTGGTAGCAGCGGAGGCGAGCGGAGGGTTTCCCGCGGCGGATTTCTGACAGTCAGACTTGTCCACAAGAACTCAACTGGCAAGGCT
GCTTTTCTGTGCTAAAACTGGGGAGCTAGTGGGCACCATGAAGATCTTCTGCAGTCGGGCCAATCCGACCACGGGGTCTGTGGAGTGGCT
GGAGGAGGATGAACACTATGATTACCACCAGGAGATTGCAAGGTCATCTTATGCAGATATGCTACATGACAAAGACAGAGTTTTCAAGCC
TATGGCTGATGCTGCTGTGAAGATTGTGGAGAAAAATGGCTTTAGTGATAAGATTAAGGTTATCAACAAGCATTCCACCGAGGTGACTGT
AGGTCCAGAGGGTGACATGCCATGCCGTGCCAACATCCTGGTCACAGAGTTGTTTGACACAGAGCTGATCGGGGAGGGGGCGCTGCCCTC
CTATGAGCACGCACACAGGCATCTCGTGGAGGAAAATTGTGAGGCCGTGCCCCACAGAGCCACCGTCTATGCACAGCTGGTGGAGTCCGG
GAGGATGTGGTCGTGGAACAAGCTATTTCCCATCCACGTGCAGACCAGCCTCGGAGAGCAGGTCATCGTCCCTCCCGTTGACGTGGAGAG
CTGCCCTGGCGCACCCTCTGTCTGTGACATTCAGCTGAACCAGGTGTCACCAGCCGACTTTACAGTCCTCAGCGATGTGCTGCCCATGTT
CAGCATAGACTTCAGCAAGCAAGTCAGTAGCTCAGCAGCCTGCCATAGCAGGCGGTTTGAACCTCTGACATCTGGCCGAGCTCAGGTGGT
TCTCTCGTGGTGGGACATTGAAATGGACCCTGAGGGGAAGATCAAGTGCACCATGGCCCCCTTCTGGGCACACTCAGACCCAGAGGAGAT
GCAGTGGCGGGACCACTGGATGCAGTGTGTGTACTTCCTGCCACAAGAGGAGCCTGTGGTGCAGGGCTCAGCGCTCTATCTGGTAGCCCA
CCACGATGACTACTGCGTATGGTACAGCCTGCAGAGGACCAGCCCTGAAAAGAATGAGAGAGTCCGCCAGATGCGCCCCGTGTGTGACTG
CCAGGCTCACCTGCTCTGGAACCGGCCTCGGTTTGGAGAGATCAATGACCAGGACAGAACTGATCGATACGTCCAGGCTCTGAGGACCCA
TAAAGCCAAGGTAGAAGCAATGACCCTGGACCTCGCTCTGCTCCGTAGCGTGCAGCATTTTGCTGAAGCATTCAAGGCCAAGAATGTGCC
TCTTCATGTGCTTGTGTGCAACGCAGCAACTTTTGCTCTACCCTGGAGTCTCACCAAAGATGGCCTGGAGACCACCTTTCAAGTGAATCA
TCTGGGGCACTTCTACCTTGTCCAGCTCCTCCAGGATGTTTTGTGCCGCTCAGCTCCTGCCCGTGTCATTGTGGTCTCCTCAGAGTCCCA
TCGATTTACAGATATTAACGACTCCTTGGGAAAACTGGACTTCAGTCGCCTCTCTCCAACAAAAAACGACTATTGGGCGATGCTGGCTTA
TAACAGGTCCAAGCTCTGCAACATCCTCTTCTCCAACGAGCTGCACCGTCGCCTCTCCCCACGCGGGGTCACGTCGAACGCAGTGCATCC
TGGAAATATGATGTACTCCAACATTCATCGCAGCTGGTGGGTGTACACACTGCTGTTTACCTTGGCGAGGCCTTTCACCAAGTCCATGCA
ACAGGGAGCTGCCACCACCGTGTACTGTGCTGCTGTCCCAGAACTGGAGGGTCTGGGAGGGATGTACTTCAACAACTGCTGCCGCTGCAT
GCCCTCACCAGAAGCTCAGAGCGAAGAGACGGCCCGGACCCTGTGGGCGCTCAGCGAGAGGCTGATCCAAGAACGGCTTGGCAGCCAGTC
CGGCTAAGTGGAGCTCAGAGCGGATGGGCACACACACCCGCCCTGTGTGTGTCCCCTCACGCAAGTGCCAGGGCTGGGCCCCTTCCAAAT
GTCCCTCCAACACAGATCCGCAAGAGTAAAGGAAATAAGAGCAGTCACAACAGAGTGAAAAATCTTAAGTACCAATGGGAAGCAGGGAAT
TCCTGGGGTAAAGTATCACTTTTCTGGGGCTGGGCTAGGCATAGGTCTCTTTGCTTTCTGGTGGTGGCCTGTTTGAAAGTAAAAACCTGC
TTGGTGTGTAGGTTCCGTATCTCCCTGGAGAAGCACCAGCAATTCTCTTTCTTTTACTGTTATAGAATAGCCTGAGGTCCCCTCGTCCCA
TCCAGCTACCACCACGGCCACCACTGCAGCCGGGGGCTGGCCTTCTCCTACTTAGGGAAGAAAAAGCAAGTGTTCACTGCTCCTTGCTGC
ATTGATCCAGGAGATAATTGTTTCATTCATCCTGACCAAGACTGAGCCAGCTTAGCAACTGCTGGGGAGACAAATCTCAGAACCTTGTCC
CAGCCAGTGAGGATGACAGTGACACCCAGAGGGAGTAGAATACGCAGAACTACCAGGTGGCAAAGTACTTGTCATAGACTCCTTTGCTAA
TGCTATGCAAAAAATTCTTTAGAGATTATAACAAATTTTTCAAATCATTCCTTAGATACCTTGAAAGGCAGGAAGGGAAGCGTATATACT
TAAGAATACACAGGATATTTTGGGGGGCAGAGAATAAAACGTTAGTTAATCCCTTTGTCTGTCAATCACAGTCTCAGTTCTCTTGCTTTC

>68942_68942_4_PRMT7-WWOX_PRMT7_chr16_68380183_ENST00000449359_WWOX_chr16_78420757_ENST00000566780_length(amino acids)=611AA_BP=369
MSTRTQLARLLFCAKTGELVGTMKIFCSRANPTTGSVEWLEEDEHYDYHQEIARSSYADMLHDKDRVFKPMADAAVKIVEKNGFSDKIKV
INKHSTEVTVGPEGDMPCRANILVTELFDTELIGEGALPSYEHAHRHLVEENCEAVPHRATVYAQLVESGRMWSWNKLFPIHVQTSLGEQ
VIVPPVDVESCPGAPSVCDIQLNQVSPADFTVLSDVLPMFSIDFSKQVSSSAACHSRRFEPLTSGRAQVVLSWWDIEMDPEGKIKCTMAP
FWAHSDPEEMQWRDHWMQCVYFLPQEEPVVQGSALYLVAHHDDYCVWYSLQRTSPEKNERVRQMRPVCDCQAHLLWNRPRFGEINDQDRT
DRYVQALRTHKAKVEAMTLDLALLRSVQHFAEAFKAKNVPLHVLVCNAATFALPWSLTKDGLETTFQVNHLGHFYLVQLLQDVLCRSAPA
RVIVVSSESHRFTDINDSLGKLDFSRLSPTKNDYWAMLAYNRSKLCNILFSNELHRRLSPRGVTSNAVHPGNMMYSNIHRSWWVYTLLFT

--------------------------------------------------------------
>68942_68942_5_PRMT7-WWOX_PRMT7_chr16_68382334_ENST00000339507_WWOX_chr16_78420757_ENST00000566780_length(transcript)=3843nt_BP=2243nt
CTTTGGGGTTCTGTGTGCAGCGAGCATGGTGTCCTTGGCACCAGGGTTTCGGCAGAGGAGCCTAGCGTGGGCCTACTTGGACTCCTCCGC
GTGGGGCAGCTCGGGACACCCGGGCCTGCAGGAGAGCGGGGTTCTAGGCTGGCCCCGGCTCTGCAGTGCAGCCGGGTGCCTGCCACTCGC
GGGGCTCTGTCGCAGTACTCGTGCCTGGCGCCTCCCCTCAGCCACAGAGACCGCAGTAGCTCCAACCATCGCACCCCTAACTGGGCCACG
AGTTCTCTGATTGCCAGACCTGTTGTCTTTGCCACTCACTGTTCTGAGTAATTGGAGAGTCGTGTATTCACTACACGCCAACCAGAGTGG
TCCTGTAAAAGCGTAAGCCTAGTGTAGATACGCTTCTGCTTAAAACTCTTGAGTGGCTCCCAGTGCTTTTAGAACAAAATCCAAACGCCT
TTCCGAAGTCGACAAGGCCCAGCTTGATTGAGCAGAAGATGTGATAGGAGATGAGGAGCGGGGGGCTTCTGCAAAAGTGCTTCGGTCGCT
CAGGCTTTTGGCACATTTTGCTTATGCAACCTAGTTCTTTCTACCTTAGGGCCTTTTCTTGGGAAAGTTGGGAGTCTCACTCTGCTGCCT
AGGCTGAGTGCAGTGGTGTGATCGAGGCGCACTGCAGCCTTGACCTCCTGGGCTCAAGCGATCCTCACCTCGGCCTACCGAGTAGCTGGG
ACTACAGGCACGCGCCACTACACTCGGATTTCTGACAGTCAGACTTGTCCACAAGAACTCAACTGGCAAGGCTGCTTTTCTGTGCTAAAA
CTGGGGAGCTAGTGGGCACCATGAAGATCTTCTGCAGTCGGGCCAATCCGACCACGGGGTCTGTGGAGTGGCTGGAGGAGGATGAACACT
ATGATTACCACCAGGAGATTGCAAGGTCATCTTATGCAGATATGCTACATGACAAAGACAGAAATGTAAAATACTACCAAGGTATCCGGG
CTGCCGTGAGCAGGGTGAAGGACAGAGGACAGAAGGCCTTGGTTCTCGACATTGGCACTGGCACGGGACTCTTGTCAATGATGGCGGTCA
CAGCAGGTGCCGACTTCTGCTATGCCATCGAGGTTTTCAAGCCTATGGCTGATGCTGCTGTGAAGATTGTGGAGAAAAATGGCTTTAGTG
ATAAGATTAAGGTTATCAACAAGCATTCCACCGAGGTGACTGTAGGTCCAGAGGGTGACATGCCATGCCGTGCCAACATCCTGGTCACAG
AGTTGTTTGACACAGAGCTGATCGGGGAGGGGGCGCTGCCCTCCTATGAGCACGCACACAGGCATCTCGTGGAGGAAAATTGTGAGGCCG
TGCCCCACAGAGCCACCGTCTATGCACAGCTGGTGGAGTCCGGGAGGATGTGGTCGTGGAACAAGCTATTTCCCATCCACGTGCAGACCA
GCCTCGGAGAGCAGGTCATCGTCCCTCCCGTTGACGTGGAGAGCTGCCCTGGCGCACCCTCTGTCTGTGACATTCAGCTGAACCAGGTGT
CACCAGCCGACTTTACAGTCCTCAGCGATGTGCTGCCCATGTTCAGCATAGACTTCAGCAAGCAAGTCAGTAGCTCAGCAGCCTGCCATA
GCAGGCGGTTTGAACCTCTGACATCTGGCCGAGCTCAGGTGGTTCTCTCGTGGTGGGACATTGAAATGGACCCTGAGGGGAAGATCAAGT
GCACCATGGCCCCCTTCTGGGCACACTCAGACCCAGAGGAGATGCAGTGGCGGGACCACTGGATGCAGTGTGTGTACTTCCTGCCACAAG
AGGAGCCTGTGGTGCAGGGCTCAGCGCTCTATCTGGTAGCCCACCACGATGACTACTGCGTATGGTACAGCCTGCAGAGGACCAGCCCTG
AAAAGAATGAGAGAGTCCGCCAGATGCGCCCCGTGTGTGACTGCCAGGCTCACCTGCTCTGGAACCGGCCTCGGTTTGGAGAGATCAATG
ACCAGGACAGAACTGATCGATACGTCCAGGCTCTGAGGACCGTGCTGAAGCCAGACAGCGTGTGCCTGTGTGTCAGCGATGGCAGCCTGC
TCTCCGTGCTGGCCCATCACCTGGGGGTGGAGCAGGTGTTTACAGTCGAGAGTTCAGCAGCTTCTCACAAACTGTTGAGAAAAATCTTCA
AGGCTAACCACTTGGAAGATAAAATTAACATCATAGAGAAACGGCCGGAATTATTAACAAATGAGGACCTACAGGGCAGAAAGCATAAAG
CCAAGGTAGAAGCAATGACCCTGGACCTCGCTCTGCTCCGTAGCGTGCAGCATTTTGCTGAAGCATTCAAGGCCAAGAATGTGCCTCTTC
ATGTGCTTGTGTGCAACGCAGCAACTTTTGCTCTACCCTGGAGTCTCACCAAAGATGGCCTGGAGACCACCTTTCAAGTGAATCATCTGG
GGCACTTCTACCTTGTCCAGCTCCTCCAGGATGTTTTGTGCCGCTCAGCTCCTGCCCGTGTCATTGTGGTCTCCTCAGAGTCCCATCGAT
TTACAGATATTAACGACTCCTTGGGAAAACTGGACTTCAGTCGCCTCTCTCCAACAAAAAACGACTATTGGGCGATGCTGGCTTATAACA
GGTCCAAGCTCTGCAACATCCTCTTCTCCAACGAGCTGCACCGTCGCCTCTCCCCACGCGGGGTCACGTCGAACGCAGTGCATCCTGGAA
ATATGATGTACTCCAACATTCATCGCAGCTGGTGGGTGTACACACTGCTGTTTACCTTGGCGAGGCCTTTCACCAAGTCCATGCAACAGG
GAGCTGCCACCACCGTGTACTGTGCTGCTGTCCCAGAACTGGAGGGTCTGGGAGGGATGTACTTCAACAACTGCTGCCGCTGCATGCCCT
CACCAGAAGCTCAGAGCGAAGAGACGGCCCGGACCCTGTGGGCGCTCAGCGAGAGGCTGATCCAAGAACGGCTTGGCAGCCAGTCCGGCT
AAGTGGAGCTCAGAGCGGATGGGCACACACACCCGCCCTGTGTGTGTCCCCTCACGCAAGTGCCAGGGCTGGGCCCCTTCCAAATGTCCC
TCCAACACAGATCCGCAAGAGTAAAGGAAATAAGAGCAGTCACAACAGAGTGAAAAATCTTAAGTACCAATGGGAAGCAGGGAATTCCTG
GGGTAAAGTATCACTTTTCTGGGGCTGGGCTAGGCATAGGTCTCTTTGCTTTCTGGTGGTGGCCTGTTTGAAAGTAAAAACCTGCTTGGT
GTGTAGGTTCCGTATCTCCCTGGAGAAGCACCAGCAATTCTCTTTCTTTTACTGTTATAGAATAGCCTGAGGTCCCCTCGTCCCATCCAG
CTACCACCACGGCCACCACTGCAGCCGGGGGCTGGCCTTCTCCTACTTAGGGAAGAAAAAGCAAGTGTTCACTGCTCCTTGCTGCATTGA
TCCAGGAGATAATTGTTTCATTCATCCTGACCAAGACTGAGCCAGCTTAGCAACTGCTGGGGAGACAAATCTCAGAACCTTGTCCCAGCC
AGTGAGGATGACAGTGACACCCAGAGGGAGTAGAATACGCAGAACTACCAGGTGGCAAAGTACTTGTCATAGACTCCTTTGCTAATGCTA
TGCAAAAAATTCTTTAGAGATTATAACAAATTTTTCAAATCATTCCTTAGATACCTTGAAAGGCAGGAAGGGAAGCGTATATACTTAAGA
ATACACAGGATATTTTGGGGGGCAGAGAATAAAACGTTAGTTAATCCCTTTGTCTGTCAATCACAGTCTCAGTTCTCTTGCTTTCACATT

>68942_68942_5_PRMT7-WWOX_PRMT7_chr16_68382334_ENST00000339507_WWOX_chr16_78420757_ENST00000566780_length(amino acids)=735AA_BP=493
MSTRTQLARLLFCAKTGELVGTMKIFCSRANPTTGSVEWLEEDEHYDYHQEIARSSYADMLHDKDRNVKYYQGIRAAVSRVKDRGQKALV
LDIGTGTGLLSMMAVTAGADFCYAIEVFKPMADAAVKIVEKNGFSDKIKVINKHSTEVTVGPEGDMPCRANILVTELFDTELIGEGALPS
YEHAHRHLVEENCEAVPHRATVYAQLVESGRMWSWNKLFPIHVQTSLGEQVIVPPVDVESCPGAPSVCDIQLNQVSPADFTVLSDVLPMF
SIDFSKQVSSSAACHSRRFEPLTSGRAQVVLSWWDIEMDPEGKIKCTMAPFWAHSDPEEMQWRDHWMQCVYFLPQEEPVVQGSALYLVAH
HDDYCVWYSLQRTSPEKNERVRQMRPVCDCQAHLLWNRPRFGEINDQDRTDRYVQALRTVLKPDSVCLCVSDGSLLSVLAHHLGVEQVFT
VESSAASHKLLRKIFKANHLEDKINIIEKRPELLTNEDLQGRKHKAKVEAMTLDLALLRSVQHFAEAFKAKNVPLHVLVCNAATFALPWS
LTKDGLETTFQVNHLGHFYLVQLLQDVLCRSAPARVIVVSSESHRFTDINDSLGKLDFSRLSPTKNDYWAMLAYNRSKLCNILFSNELHR
RLSPRGVTSNAVHPGNMMYSNIHRSWWVYTLLFTLARPFTKSMQQGAATTVYCAAVPELEGLGGMYFNNCCRCMPSPEAQSEETARTLWA

--------------------------------------------------------------
>68942_68942_6_PRMT7-WWOX_PRMT7_chr16_68382334_ENST00000441236_WWOX_chr16_78420757_ENST00000566780_length(transcript)=3695nt_BP=2095nt
CGCTTTGGGGTTCTGTGTGCAGCGAGCATGGTGTCCTTGGCACCAGGGTTTCGGCAGAGGAGCCTAGCGTGGGCCTACTTGGACTCCTCC
GCGTGGGGCAGCTCGGGACACCCGGGCCTGCAGGAGAGCGGGGTTCTAGGCTGGCCCCGGCTCTGCAGTGCAGCCGGGTGCCTGCCACTC
GCGGGGCTCTGTCGCAGTACTCGTGCCTGGCGCCTCCCCTCAGCCACAGAGACCGCAGTAGCTCCAACCATCGCACCCCTAACTGGGCCA
CGAGTTCTCTGATTGCCAGACCTGTTGTCTTTGCCACTCACTGTTCTGAGTAATTGGAGAGTCGTGTATTCACTACACGCCAACCAGAGT
GGTCCTGTAAAAGCGTAAGCCTAGTGTAGATACGCTTCTGCTTAAAACTCTTGAGTGGCTCCCAGTGCTTTTAGAACAAAATCCAAACGC
CTTTCCGAAGTCGACAAGGCCCAGCTTGATTGAGCAGAAGATGTGATAGGAGATGAGGAGCGGGGGGCTTCTGCAAAAGTGCTTCGGTCG
CTCAGGCTTTTGGCACATTTTGCTTATGCAACCTAGTTCTTTCTACCTTAGGGCCTTTTCTTGGGAAAGTTGGGAGTCTCACTCTGCTGC
CTAGGCTGAGTGCAGTGGTGTGATCGAGGCGCACTGCAGCCTTGACCTCCTGGGCTCAAGCGATCCTCACCTCGGCCTACCGAGTAGCTG
GGACTACAGGCACGCGCCACTACACTCGGATTTCTGACAGTCAGACTTGTCCACAAGAACTCAACTGGCAAGGCTGCTTTTCTGTGCTAA
AACTGGGGAGCTAGTGGGCACCATGAAGATCTTCTGCAGTCGGGCCAATCCGACCACGGGGTCTGTGGAGTGGCTGGAGGAGGATGAACA
CTATGATTACCACCAGGAGATTGCAAGGTCATCTTATGCAGATATGCTACATGACAAAGACAGAGTTTTCAAGCCTATGGCTGATGCTGC
TGTGAAGATTGTGGAGAAAAATGGCTTTAGTGATAAGATTAAGGTTATCAACAAGCATTCCACCGAGGTGACTGTAGGTCCAGAGGGTGA
CATGCCATGCCGTGCCAACATCCTGGTCACAGAGTTGTTTGACACAGAGCTGATCGGGGAGGGGGCGCTGCCCTCCTATGAGCACGCACA
CAGGCATCTCGTGGAGGAAAATTGTGAGGCCGTGCCCCACAGAGCCACCGTCTATGCACAGCTGGTGGAGTCCGGGAGGATGTGGTCGTG
GAACAAGCTATTTCCCATCCACGTGCAGACCAGCCTCGGAGAGCAGGTCATCGTCCCTCCCGTTGACGTGGAGAGCTGCCCTGGCGCACC
CTCTGTCTGTGACATTCAGCTGAACCAGGTGTCACCAGCCGACTTTACAGTCCTCAGCGATGTGCTGCCCATGTTCAGCATAGACTTCAG
CAAGCAAGTCAGTAGCTCAGCAGCCTGCCATAGCAGGCGGTTTGAACCTCTGACATCTGGCCGAGCTCAGGTGGTTCTCTCGTGGTGGGA
CATTGAAATGGACCCTGAGGGGAAGATCAAGTGCACCATGGCCCCCTTCTGGGCACACTCAGACCCAGAGGAGATGCAGTGGCGGGACCA
CTGGATGCAGTGTGTGTACTTCCTGCCACAAGAGGAGCCTGTGGTGCAGGGCTCAGCGCTCTATCTGGTAGCCCACCACGATGACTACTG
CGTATGGTACAGCCTGCAGAGGACCAGCCCTGAAAAGAATGAGAGAGTCCGCCAGATGCGCCCCGTGTGTGACTGCCAGGCTCACCTGCT
CTGGAACCGGCCTCGGTTTGGAGAGATCAATGACCAGGACAGAACTGATCGATACGTCCAGGCTCTGAGGACCGTGCTGAAGCCAGACAG
CGTGTGCCTGTGTGTCAGCGATGGCAGCCTGCTCTCCGTGCTGGCCCATCACCTGGGGGTGGAGCAGGTGTTTACAGTCGAGAGTTCAGC
AGCTTCTCACAAACTGTTGAGAAAAATCTTCAAGGCTAACCACTTGGAAGATAAAATTAACATCATAGAGAAACGGCCGGAATTATTAAC
AAATGAGGACCTACAGGGCAGAAAGCATAAAGCCAAGGTAGAAGCAATGACCCTGGACCTCGCTCTGCTCCGTAGCGTGCAGCATTTTGC
TGAAGCATTCAAGGCCAAGAATGTGCCTCTTCATGTGCTTGTGTGCAACGCAGCAACTTTTGCTCTACCCTGGAGTCTCACCAAAGATGG
CCTGGAGACCACCTTTCAAGTGAATCATCTGGGGCACTTCTACCTTGTCCAGCTCCTCCAGGATGTTTTGTGCCGCTCAGCTCCTGCCCG
TGTCATTGTGGTCTCCTCAGAGTCCCATCGATTTACAGATATTAACGACTCCTTGGGAAAACTGGACTTCAGTCGCCTCTCTCCAACAAA
AAACGACTATTGGGCGATGCTGGCTTATAACAGGTCCAAGCTCTGCAACATCCTCTTCTCCAACGAGCTGCACCGTCGCCTCTCCCCACG
CGGGGTCACGTCGAACGCAGTGCATCCTGGAAATATGATGTACTCCAACATTCATCGCAGCTGGTGGGTGTACACACTGCTGTTTACCTT
GGCGAGGCCTTTCACCAAGTCCATGCAACAGGGAGCTGCCACCACCGTGTACTGTGCTGCTGTCCCAGAACTGGAGGGTCTGGGAGGGAT
GTACTTCAACAACTGCTGCCGCTGCATGCCCTCACCAGAAGCTCAGAGCGAAGAGACGGCCCGGACCCTGTGGGCGCTCAGCGAGAGGCT
GATCCAAGAACGGCTTGGCAGCCAGTCCGGCTAAGTGGAGCTCAGAGCGGATGGGCACACACACCCGCCCTGTGTGTGTCCCCTCACGCA
AGTGCCAGGGCTGGGCCCCTTCCAAATGTCCCTCCAACACAGATCCGCAAGAGTAAAGGAAATAAGAGCAGTCACAACAGAGTGAAAAAT
CTTAAGTACCAATGGGAAGCAGGGAATTCCTGGGGTAAAGTATCACTTTTCTGGGGCTGGGCTAGGCATAGGTCTCTTTGCTTTCTGGTG
GTGGCCTGTTTGAAAGTAAAAACCTGCTTGGTGTGTAGGTTCCGTATCTCCCTGGAGAAGCACCAGCAATTCTCTTTCTTTTACTGTTAT
AGAATAGCCTGAGGTCCCCTCGTCCCATCCAGCTACCACCACGGCCACCACTGCAGCCGGGGGCTGGCCTTCTCCTACTTAGGGAAGAAA
AAGCAAGTGTTCACTGCTCCTTGCTGCATTGATCCAGGAGATAATTGTTTCATTCATCCTGACCAAGACTGAGCCAGCTTAGCAACTGCT
GGGGAGACAAATCTCAGAACCTTGTCCCAGCCAGTGAGGATGACAGTGACACCCAGAGGGAGTAGAATACGCAGAACTACCAGGTGGCAA
AGTACTTGTCATAGACTCCTTTGCTAATGCTATGCAAAAAATTCTTTAGAGATTATAACAAATTTTTCAAATCATTCCTTAGATACCTTG
AAAGGCAGGAAGGGAAGCGTATATACTTAAGAATACACAGGATATTTTGGGGGGCAGAGAATAAAACGTTAGTTAATCCCTTTGTCTGTC
AATCACAGTCTCAGTTCTCTTGCTTTCACATTGTACTTAAACCTCCTGCTGTGCCTCGCATCCTATGCTTAATAAAAGAACATGCTTGAA

>68942_68942_6_PRMT7-WWOX_PRMT7_chr16_68382334_ENST00000441236_WWOX_chr16_78420757_ENST00000566780_length(amino acids)=685AA_BP=443
MSTRTQLARLLFCAKTGELVGTMKIFCSRANPTTGSVEWLEEDEHYDYHQEIARSSYADMLHDKDRVFKPMADAAVKIVEKNGFSDKIKV
INKHSTEVTVGPEGDMPCRANILVTELFDTELIGEGALPSYEHAHRHLVEENCEAVPHRATVYAQLVESGRMWSWNKLFPIHVQTSLGEQ
VIVPPVDVESCPGAPSVCDIQLNQVSPADFTVLSDVLPMFSIDFSKQVSSSAACHSRRFEPLTSGRAQVVLSWWDIEMDPEGKIKCTMAP
FWAHSDPEEMQWRDHWMQCVYFLPQEEPVVQGSALYLVAHHDDYCVWYSLQRTSPEKNERVRQMRPVCDCQAHLLWNRPRFGEINDQDRT
DRYVQALRTVLKPDSVCLCVSDGSLLSVLAHHLGVEQVFTVESSAASHKLLRKIFKANHLEDKINIIEKRPELLTNEDLQGRKHKAKVEA
MTLDLALLRSVQHFAEAFKAKNVPLHVLVCNAATFALPWSLTKDGLETTFQVNHLGHFYLVQLLQDVLCRSAPARVIVVSSESHRFTDIN
DSLGKLDFSRLSPTKNDYWAMLAYNRSKLCNILFSNELHRRLSPRGVTSNAVHPGNMMYSNIHRSWWVYTLLFTLARPFTKSMQQGAATT

--------------------------------------------------------------
>68942_68942_7_PRMT7-WWOX_PRMT7_chr16_68382334_ENST00000449359_WWOX_chr16_78420757_ENST00000566780_length(transcript)=2990nt_BP=1390nt
AAAAGTGGTAGCAGCGGAGGCGAGCGGAGGGTTTCCCGCGGCGGATTTCTGACAGTCAGACTTGTCCACAAGAACTCAACTGGCAAGGCT
GCTTTTCTGTGCTAAAACTGGGGAGCTAGTGGGCACCATGAAGATCTTCTGCAGTCGGGCCAATCCGACCACGGGGTCTGTGGAGTGGCT
GGAGGAGGATGAACACTATGATTACCACCAGGAGATTGCAAGGTCATCTTATGCAGATATGCTACATGACAAAGACAGAGTTTTCAAGCC
TATGGCTGATGCTGCTGTGAAGATTGTGGAGAAAAATGGCTTTAGTGATAAGATTAAGGTTATCAACAAGCATTCCACCGAGGTGACTGT
AGGTCCAGAGGGTGACATGCCATGCCGTGCCAACATCCTGGTCACAGAGTTGTTTGACACAGAGCTGATCGGGGAGGGGGCGCTGCCCTC
CTATGAGCACGCACACAGGCATCTCGTGGAGGAAAATTGTGAGGCCGTGCCCCACAGAGCCACCGTCTATGCACAGCTGGTGGAGTCCGG
GAGGATGTGGTCGTGGAACAAGCTATTTCCCATCCACGTGCAGACCAGCCTCGGAGAGCAGGTCATCGTCCCTCCCGTTGACGTGGAGAG
CTGCCCTGGCGCACCCTCTGTCTGTGACATTCAGCTGAACCAGGTGTCACCAGCCGACTTTACAGTCCTCAGCGATGTGCTGCCCATGTT
CAGCATAGACTTCAGCAAGCAAGTCAGTAGCTCAGCAGCCTGCCATAGCAGGCGGTTTGAACCTCTGACATCTGGCCGAGCTCAGGTGGT
TCTCTCGTGGTGGGACATTGAAATGGACCCTGAGGGGAAGATCAAGTGCACCATGGCCCCCTTCTGGGCACACTCAGACCCAGAGGAGAT
GCAGTGGCGGGACCACTGGATGCAGTGTGTGTACTTCCTGCCACAAGAGGAGCCTGTGGTGCAGGGCTCAGCGCTCTATCTGGTAGCCCA
CCACGATGACTACTGCGTATGGTACAGCCTGCAGAGGACCAGCCCTGAAAAGAATGAGAGAGTCCGCCAGATGCGCCCCGTGTGTGACTG
CCAGGCTCACCTGCTCTGGAACCGGCCTCGGTTTGGAGAGATCAATGACCAGGACAGAACTGATCGATACGTCCAGGCTCTGAGGACCGT
GCTGAAGCCAGACAGCGTGTGCCTGTGTGTCAGCGATGGCAGCCTGCTCTCCGTGCTGGCCCATCACCTGGGGGTGGAGCAGGTGTTTAC
AGTCGAGAGTTCAGCAGCTTCTCACAAACTGTTGAGAAAAATCTTCAAGGCTAACCACTTGGAAGATAAAATTAACATCATAGAGAAACG
GCCGGAATTATTAACAAATGAGGACCTACAGGGCAGAAAGCATAAAGCCAAGGTAGAAGCAATGACCCTGGACCTCGCTCTGCTCCGTAG
CGTGCAGCATTTTGCTGAAGCATTCAAGGCCAAGAATGTGCCTCTTCATGTGCTTGTGTGCAACGCAGCAACTTTTGCTCTACCCTGGAG
TCTCACCAAAGATGGCCTGGAGACCACCTTTCAAGTGAATCATCTGGGGCACTTCTACCTTGTCCAGCTCCTCCAGGATGTTTTGTGCCG
CTCAGCTCCTGCCCGTGTCATTGTGGTCTCCTCAGAGTCCCATCGATTTACAGATATTAACGACTCCTTGGGAAAACTGGACTTCAGTCG
CCTCTCTCCAACAAAAAACGACTATTGGGCGATGCTGGCTTATAACAGGTCCAAGCTCTGCAACATCCTCTTCTCCAACGAGCTGCACCG
TCGCCTCTCCCCACGCGGGGTCACGTCGAACGCAGTGCATCCTGGAAATATGATGTACTCCAACATTCATCGCAGCTGGTGGGTGTACAC
ACTGCTGTTTACCTTGGCGAGGCCTTTCACCAAGTCCATGCAACAGGGAGCTGCCACCACCGTGTACTGTGCTGCTGTCCCAGAACTGGA
GGGTCTGGGAGGGATGTACTTCAACAACTGCTGCCGCTGCATGCCCTCACCAGAAGCTCAGAGCGAAGAGACGGCCCGGACCCTGTGGGC
GCTCAGCGAGAGGCTGATCCAAGAACGGCTTGGCAGCCAGTCCGGCTAAGTGGAGCTCAGAGCGGATGGGCACACACACCCGCCCTGTGT
GTGTCCCCTCACGCAAGTGCCAGGGCTGGGCCCCTTCCAAATGTCCCTCCAACACAGATCCGCAAGAGTAAAGGAAATAAGAGCAGTCAC
AACAGAGTGAAAAATCTTAAGTACCAATGGGAAGCAGGGAATTCCTGGGGTAAAGTATCACTTTTCTGGGGCTGGGCTAGGCATAGGTCT
CTTTGCTTTCTGGTGGTGGCCTGTTTGAAAGTAAAAACCTGCTTGGTGTGTAGGTTCCGTATCTCCCTGGAGAAGCACCAGCAATTCTCT
TTCTTTTACTGTTATAGAATAGCCTGAGGTCCCCTCGTCCCATCCAGCTACCACCACGGCCACCACTGCAGCCGGGGGCTGGCCTTCTCC
TACTTAGGGAAGAAAAAGCAAGTGTTCACTGCTCCTTGCTGCATTGATCCAGGAGATAATTGTTTCATTCATCCTGACCAAGACTGAGCC
AGCTTAGCAACTGCTGGGGAGACAAATCTCAGAACCTTGTCCCAGCCAGTGAGGATGACAGTGACACCCAGAGGGAGTAGAATACGCAGA
ACTACCAGGTGGCAAAGTACTTGTCATAGACTCCTTTGCTAATGCTATGCAAAAAATTCTTTAGAGATTATAACAAATTTTTCAAATCAT
TCCTTAGATACCTTGAAAGGCAGGAAGGGAAGCGTATATACTTAAGAATACACAGGATATTTTGGGGGGCAGAGAATAAAACGTTAGTTA
ATCCCTTTGTCTGTCAATCACAGTCTCAGTTCTCTTGCTTTCACATTGTACTTAAACCTCCTGCTGTGCCTCGCATCCTATGCTTAATAA

>68942_68942_7_PRMT7-WWOX_PRMT7_chr16_68382334_ENST00000449359_WWOX_chr16_78420757_ENST00000566780_length(amino acids)=685AA_BP=443
MSTRTQLARLLFCAKTGELVGTMKIFCSRANPTTGSVEWLEEDEHYDYHQEIARSSYADMLHDKDRVFKPMADAAVKIVEKNGFSDKIKV
INKHSTEVTVGPEGDMPCRANILVTELFDTELIGEGALPSYEHAHRHLVEENCEAVPHRATVYAQLVESGRMWSWNKLFPIHVQTSLGEQ
VIVPPVDVESCPGAPSVCDIQLNQVSPADFTVLSDVLPMFSIDFSKQVSSSAACHSRRFEPLTSGRAQVVLSWWDIEMDPEGKIKCTMAP
FWAHSDPEEMQWRDHWMQCVYFLPQEEPVVQGSALYLVAHHDDYCVWYSLQRTSPEKNERVRQMRPVCDCQAHLLWNRPRFGEINDQDRT
DRYVQALRTVLKPDSVCLCVSDGSLLSVLAHHLGVEQVFTVESSAASHKLLRKIFKANHLEDKINIIEKRPELLTNEDLQGRKHKAKVEA
MTLDLALLRSVQHFAEAFKAKNVPLHVLVCNAATFALPWSLTKDGLETTFQVNHLGHFYLVQLLQDVLCRSAPARVIVVSSESHRFTDIN
DSLGKLDFSRLSPTKNDYWAMLAYNRSKLCNILFSNELHRRLSPRGVTSNAVHPGNMMYSNIHRSWWVYTLLFTLARPFTKSMQQGAATT

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Fusion Gene PPI Analysis for PRMT7-WWOX


check button Go to ChiPPI (Chimeric Protein-Protein interactions) to see the chimeric PPI interaction in

ChiPPI page.


check button Protein-protein interactors with each fusion partner protein in wild-type (BIOGRID-3.4.160)
HgeneHgene's interactorsTgeneTgene's interactors


check button - Retained PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenStill interaction with
TgeneWWOXchr16:68380183chr16:78420757ENST0000035586006125_4140190.0MAPT
TgeneWWOXchr16:68380183chr16:78420757ENST0000040265505125_4140312.0MAPT
TgeneWWOXchr16:68380183chr16:78420757ENST0000040688406125_4140235.0MAPT
TgeneWWOXchr16:68380183chr16:78420757ENST0000056981801125_414037.0MAPT
TgeneWWOXchr16:68382334chr16:78420757ENST0000035586006125_4140190.0MAPT
TgeneWWOXchr16:68382334chr16:78420757ENST0000040265505125_4140312.0MAPT
TgeneWWOXchr16:68382334chr16:78420757ENST0000040688406125_4140235.0MAPT
TgeneWWOXchr16:68382334chr16:78420757ENST0000056981801125_414037.0MAPT


check button - Lost PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with
TgeneWWOXchr16:68380183chr16:78420757ENST00000408984410125_414172.0311.6666666666667MAPT
TgeneWWOXchr16:68380183chr16:78420757ENST0000056678049125_414172.0415.0MAPT
TgeneWWOXchr16:68382334chr16:78420757ENST00000408984410125_414172.0311.6666666666667MAPT
TgeneWWOXchr16:68382334chr16:78420757ENST0000056678049125_414172.0415.0MAPT


check button - Retained PPIs, but lost function due to frame-shift fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


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Related Drugs for PRMT7-WWOX


check button Drugs targeting genes involved in this fusion gene.
(DrugBank Version 5.1.8 2021-05-08)
PartnerGeneUniProtAccDrugBank IDDrug nameDrug activityDrug typeDrug status

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Related Diseases for PRMT7-WWOX


check button Diseases associated with fusion partners.
(DisGeNet 4.0)
PartnerGeneDisease IDDisease name# pubmedsSource