FusionGDB Logo

Home

Download

Statistics

Examples

Help

Contact
Center for Computational Systems Medicine
leaf

Fusion Gene Summary

leaf

Fusion Gene ORF analysis

leaf

Fusion Genomic Features

leaf

Fusion Protein Features

leaf

Fusion Gene Sequence

leaf

Fusion Gene PPI analysis

leaf

Related Drugs

leaf

Related Diseases

Fusion gene:PRPS2-RALGAPB (FusionGDB2 ID:69092)

Fusion Gene Summary for PRPS2-RALGAPB

check button Fusion gene summary
Fusion gene informationFusion gene name: PRPS2-RALGAPB
Fusion gene ID: 69092
HgeneTgene
Gene symbol

PRPS2

RALGAPB

Gene ID

5634

57148

Gene namephosphoribosyl pyrophosphate synthetase 2Ral GTPase activating protein non-catalytic subunit beta
SynonymsPRSIIKIAA1219|RalGAPbeta
Cytomap

Xp22.2

20q11.23

Type of geneprotein-codingprotein-coding
Descriptionribose-phosphate pyrophosphokinase 2PPRibP synthetasePRS-IIphosphoribosyl pyrophosphate synthase IIribose-phosphate diphosphokinase 2testicular secretory protein Li 41ral GTPase-activating protein subunit betaRal GTPase activating protein non-catalytic beta subunitRal GTPase activating protein, beta subunit (non-catalytic)
Modification date2020031320200313
UniProtAcc..
Ensembl transtripts involved in fusion geneENST00000380668, ENST00000398491, 
ENST00000489404, 		ENST00000397040, 
ENST00000490114, ENST00000537204, 
ENST00000262879, ENST00000397038, 
ENST00000397042, 
Fusion gene scores* DoF score2 X 4 X 2=163 X 3 X 3=27
# samples 43
** MAII scorelog2(4/16*10)=1.32192809488736
effective Gene in Pan-Cancer Fusion Genes (eGinPCFGs).
DoF>8 and MAII>0		log2(3/27*10)=0.15200309344505
effective Gene in Pan-Cancer Fusion Genes (eGinPCFGs).
DoF>8 and MAII>0
Context

PubMed: PRPS2 [Title/Abstract] AND RALGAPB [Title/Abstract] AND fusion [Title/Abstract]

Most frequent breakpointPRPS2(12817509)-RALGAPB(37198531), # samples:1
Anticipated loss of major functional domain due to fusion event.
* DoF score (Degree of Frequency) = # partners X # break points X # cancer types
** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10)

check button Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez
PartnerGeneGO IDGO termPubMed ID

check buttonFusion gene breakpoints across PRPS2 (5'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.
all structure

check buttonFusion gene breakpoints across RALGAPB (3'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.
all structure

check button Fusion gene information from two resources (ChiTars 5.0 and ChimerDB 4.0)
* All genome coordinats were lifted-over on hg19.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
SourceDiseaseSampleHgeneHchrHbpHstrandTgeneTchrTbpTstrand
ChimerDB4STADTCGA-BR-A4PD-01APRPS2chrX

12817509

+RALGAPBchr20

37198531

+


Top

Fusion Gene ORF analysis for PRPS2-RALGAPB

check button Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
ORFHenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrand
5CDS-intronENST00000380668ENST00000397040PRPS2chrX

12817509

+RALGAPBchr20

37198531

+
5CDS-intronENST00000380668ENST00000490114PRPS2chrX

12817509

+RALGAPBchr20

37198531

+
5CDS-intronENST00000380668ENST00000537204PRPS2chrX

12817509

+RALGAPBchr20

37198531

+
5CDS-intronENST00000398491ENST00000397040PRPS2chrX

12817509

+RALGAPBchr20

37198531

+
5CDS-intronENST00000398491ENST00000490114PRPS2chrX

12817509

+RALGAPBchr20

37198531

+
5CDS-intronENST00000398491ENST00000537204PRPS2chrX

12817509

+RALGAPBchr20

37198531

+
5CDS-intronENST00000489404ENST00000397040PRPS2chrX

12817509

+RALGAPBchr20

37198531

+
5CDS-intronENST00000489404ENST00000490114PRPS2chrX

12817509

+RALGAPBchr20

37198531

+
5CDS-intronENST00000489404ENST00000537204PRPS2chrX

12817509

+RALGAPBchr20

37198531

+
In-frameENST00000380668ENST00000262879PRPS2chrX

12817509

+RALGAPBchr20

37198531

+
In-frameENST00000380668ENST00000397038PRPS2chrX

12817509

+RALGAPBchr20

37198531

+
In-frameENST00000380668ENST00000397042PRPS2chrX

12817509

+RALGAPBchr20

37198531

+
In-frameENST00000398491ENST00000262879PRPS2chrX

12817509

+RALGAPBchr20

37198531

+
In-frameENST00000398491ENST00000397038PRPS2chrX

12817509

+RALGAPBchr20

37198531

+
In-frameENST00000398491ENST00000397042PRPS2chrX

12817509

+RALGAPBchr20

37198531

+
In-frameENST00000489404ENST00000262879PRPS2chrX

12817509

+RALGAPBchr20

37198531

+
In-frameENST00000489404ENST00000397038PRPS2chrX

12817509

+RALGAPBchr20

37198531

+
In-frameENST00000489404ENST00000397042PRPS2chrX

12817509

+RALGAPBchr20

37198531

+

check buttonORFfinder result based on the fusion transcript sequence of in-frame fusion genes.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandSeq length
(transcript)		BP loci
(transcript)		Predicted start
(transcript)		Predicted stop
(transcript)		Seq length
(amino acids)
ENST00000380668PRPS2chrX12817509+ENST00000262879RALGAPBchr2037198531+4857434128964278
ENST00000380668PRPS2chrX12817509+ENST00000397042RALGAPBchr2037198531+4857434128964278
ENST00000380668PRPS2chrX12817509+ENST00000397038RALGAPBchr2037198531+4859434128964278
ENST00000398491PRPS2chrX12817509+ENST00000262879RALGAPBchr2037198531+464622328753241
ENST00000398491PRPS2chrX12817509+ENST00000397042RALGAPBchr2037198531+464622328753241
ENST00000398491PRPS2chrX12817509+ENST00000397038RALGAPBchr2037198531+464822328753241
ENST00000489404PRPS2chrX12817509+ENST00000262879RALGAPBchr2037198531+473931610846278
ENST00000489404PRPS2chrX12817509+ENST00000397042RALGAPBchr2037198531+473931610846278
ENST00000489404PRPS2chrX12817509+ENST00000397038RALGAPBchr2037198531+474131610846278

check buttonDeepORF prediction of the coding potential based on the fusion transcript sequence of in-frame fusion genes. DeepORF is a coding potential classifier based on convolutional neural network by comparing the real Ribo-seq data. If the no-coding score < 0.5 and coding score > 0.5, then the in-frame fusion transcript is predicted as being likely translated.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandNo-coding scoreCoding score
ENST00000380668ENST00000262879PRPS2chrX12817509+RALGAPBchr2037198531+0.0006809770.9993191
ENST00000380668ENST00000397042PRPS2chrX12817509+RALGAPBchr2037198531+0.0006809770.9993191
ENST00000380668ENST00000397038PRPS2chrX12817509+RALGAPBchr2037198531+0.0006803990.9993197
ENST00000398491ENST00000262879PRPS2chrX12817509+RALGAPBchr2037198531+0.0054983180.9945017
ENST00000398491ENST00000397042PRPS2chrX12817509+RALGAPBchr2037198531+0.0054983180.9945017
ENST00000398491ENST00000397038PRPS2chrX12817509+RALGAPBchr2037198531+0.0055698430.9944301
ENST00000489404ENST00000262879PRPS2chrX12817509+RALGAPBchr2037198531+0.0006581430.9993418
ENST00000489404ENST00000397042PRPS2chrX12817509+RALGAPBchr2037198531+0.0006581430.9993418
ENST00000489404ENST00000397038PRPS2chrX12817509+RALGAPBchr2037198531+0.0006578670.99934214

Top

Fusion Genomic Features for PRPS2-RALGAPB


check buttonFusionAI prediction of the potential fusion gene breakpoint based on the pre-mature RNA sequence context (+/- 5kb of individual partner genes, total 20kb length sequence). FusionAI is a fusion gene breakpoint classifier based on convolutional neural network by comparing the fusion positive and negative sequence context of ~ 20K fusion gene data. From here, we can have the relative potentency of the 20K genomic sequence how individual sequnce will be likely used as the gene fusion breakpoints.
HgeneHchrHbpHstrandTgeneTchrTbpTstrand1-pp (fusion gene breakpoint)
PRPS2chrX12817509+RALGAPBchr2037198530+0.0002528080.9997472
PRPS2chrX12817509+RALGAPBchr2037198530+0.0002528080.9997472

check buttonDistribution of 44 human genomic features loci across 20kb length fusion breakpoint regions. We integrated a total of 44 different types of human genomic feature loci information across five big categories including virus integration sites, repeats, structural variants, chromatin states, and gene expression regulation. More details are in help page.
genomic feature

check buttonDistribution of 44 human genomic features loci across 20kb length fusion breakpoint regions that are ovelapped with the top 1% feature importance score regions. More details are in help page.
genomic feature of top 1%

Top

Fusion Protein Features for PRPS2-RALGAPB


check button Four levels of functional features of fusion genes
Go to FGviewer search page for the most frequent breakpoint (https://ccsmweb.uth.edu/FGviewer/chrX:12817509/chr20:37198531)
- FGviewer provides the online visualization of the retention search of the protein functional features across DNA, RNA, protein, and pathological levels.
- How to search
1. Put your fusion gene symbol.
2. Press the tab key until there will be shown the breakpoint information filled.
4. Go down and press 'Search' tab twice.
4. Go down to have the hyperlink of the search result.
5. Click the hyperlink.
6. See the FGviewer result for your fusion gene.
FGviewer

check buttonMain function of each fusion partner protein. (from UniProt)
HgeneTgene
..
FUNCTION: Transcriptional activator which is required for calcium-dependent dendritic growth and branching in cortical neurons. Recruits CREB-binding protein (CREBBP) to nuclear bodies. Component of the CREST-BRG1 complex, a multiprotein complex that regulates promoter activation by orchestrating a calcium-dependent release of a repressor complex and a recruitment of an activator complex. In resting neurons, transcription of the c-FOS promoter is inhibited by BRG1-dependent recruitment of a phospho-RB1-HDAC1 repressor complex. Upon calcium influx, RB1 is dephosphorylated by calcineurin, which leads to release of the repressor complex. At the same time, there is increased recruitment of CREBBP to the promoter by a CREST-dependent mechanism, which leads to transcriptional activation. The CREST-BRG1 complex also binds to the NR2B promoter, and activity-dependent induction of NR2B expression involves a release of HDAC1 and recruitment of CREBBP (By similarity). {ECO:0000250}.FUNCTION: Transcriptional activator which is required for calcium-dependent dendritic growth and branching in cortical neurons. Recruits CREB-binding protein (CREBBP) to nuclear bodies. Component of the CREST-BRG1 complex, a multiprotein complex that regulates promoter activation by orchestrating a calcium-dependent release of a repressor complex and a recruitment of an activator complex. In resting neurons, transcription of the c-FOS promoter is inhibited by BRG1-dependent recruitment of a phospho-RB1-HDAC1 repressor complex. Upon calcium influx, RB1 is dephosphorylated by calcineurin, which leads to release of the repressor complex. At the same time, there is increased recruitment of CREBBP to the promoter by a CREST-dependent mechanism, which leads to transcriptional activation. The CREST-BRG1 complex also binds to the NR2B promoter, and activity-dependent induction of NR2B expression involves a release of HDAC1 and recruitment of CREBBP (By similarity). {ECO:0000250}.

check buttonRetention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at

download page


* Minus value of BPloci means that the break pointn is located before the CDS.
- In-frame and retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
HgenePRPS2chrX:12817509chr20:37198531ENST00000380668+2796_101102319.0Nucleotide bindingATP
TgeneRALGAPBchrX:12817509chr20:37198531ENST0000039703825301149_139210971274.0DomainRap-GAP

- In-frame and not-retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
HgenePRPS2chrX:12817509chr20:37198531ENST00000398491+1796_1010322.0Nucleotide bindingATP
HgenePRPS2chrX:12817509chr20:37198531ENST00000380668+27212_227102319.0RegionBinding of phosphoribosylpyrophosphate
HgenePRPS2chrX:12817509chr20:37198531ENST00000398491+17212_2270322.0RegionBinding of phosphoribosylpyrophosphate
TgeneRALGAPBchrX:12817509chr20:37198531ENST0000026287925301149_139213181495.0DomainRap-GAP
TgeneRALGAPBchrX:12817509chr20:37198531ENST0000039704025301149_139213181495.0DomainRap-GAP


Top

Fusion Gene Sequence for PRPS2-RALGAPB


check button For in-frame fusion transcripts, we provide the fusion transcript sequences and fusion amino acid sequences. To have fusion amino acid sequence, we ran ORFfinder and chose the longest ORF among the all predicted ones.
>69092_69092_1_PRPS2-RALGAPB_PRPS2_chrX_12817509_ENST00000380668_RALGAPB_chr20_37198531_ENST00000262879_length(transcript)=4857nt_BP=434nt
CCTCCCCTTCCCTACATCTAGCCGCCGCGCTTTCCCGCTCCCGCAGCAGCAGCCTCCCGCGTCGCTGTCGCTGTTGCCTCCGCCACCTCC
TCCGCCGCCGCGCGCCCCTCGGAGTTCCGCGCCCCACCATGCCCAACATCGTGCTGTTCAGCGGCAGCTCGCATCAGGACCTGTCCCAGC
GCGTGGCCGACCGCCTGGGCCTGGAGCTGGGCAAGGTGGTCACGAAGAAGTTCAGCAACCAGGAGACCAGCGTGGAGATTGGTGAAAGCG
TGAGAGGGGAAGATGTCTACATCATCCAGAGCGGCTGCGGGGAAATTAACGACAACCTGATGGAACTCCTCATCATGATCAATGCCTGCA
AGATTGCGTCATCATCCAGAGTAACTGCCGTGATCCCGTGTTTCCCATACGCCCGACAAGATAAAAAGGACAAGCTCAGTCCCAGTTCCA
GAATGAGGAAGCTGCCTCAGGGTCGCCCTGTTCCTCCCCTTGGACCTGAGACAAGAGTTTCTGTAGTCTGGGTGGAACGCTATGATGATA
TAGAAAACTTTCCCCTCTCAGAGCTGATGACAGAGATCAGTACTGGTGTGGAAACTACTGCAAATAGTAGCACTTCACTGAGATCTACAA
CTCTTGAAAAAGAAGTTCCTGTCATCTTCATCCACCCTTTAAACACTGGATTATTCCGGATAAAAATTCAAGGAGCCACTGGAAAATTTA
ATATGGTCATCCCTCTTGTGGATGGGATGATTGTCAGCAGGCGAGCTCTTGGCTTTCTGGTGAGGCAGACTGTAATTAACATTTGTAGAA
GAAAGAGACTGGAAAGTGACTCCTACAGTCCCCCCCATGTCCGCCGGAAACAGAAAATCACCGACATTGTCAACAAGTACCGGAACAAGC
AGCTGGAGCCAGAGTTTTATACTTCACTTTTCCAGGAGGTTGGACTCAAGAACTGCAGTTCTTAGACCACTGAATTTCTAAGACTGTTGA
ACTCCAGTTTGGGAACTATAACACAGCAGAACAGTTTGATAGGTGATCACTGTAAAAATAAAAACAAATCACTCCCAAGAGCTTACTGTT
TAATCACCAGAATAGAAGAAACACATTATAACCCATTTGATAGAAGACTTTGGGCTATCTAGTGAAATGGGCTCCCAGACACAATCACAC
TCCTGCTGATAATGATGATATACATTTTAGCCATAAACTTTCTTTTAAAAGTGACAATTTTAGTTAAACATAAGCCTTTTGAGGAGAAAG
GCTTTTATGCATCTCAGTTAAACACGTGCATTGGTAGTATCAACAAATTTGCAATATAGAAGTTGAAGATAGTTTTTTACCTCACTTTTT
AGGAGGTTGTATTCAAAATTAAAATCTCAGAATCTTACAGGACATTTAAAGACTCATGTTGATAGCATGGAGGAGAAGGAAAGAAGTCAC
AGCCTTCTACTCAGTTGTAGGTCTTCTTGTCATCCAGCTGTCACACTGACAAAAAGAAAAGATGATACATGTTTTTTGCTCAGATAAGAA
GCCTGACATTAAAAGATGTCATATTTTTTTCTCCACATTTCAAAAAGTTGTCCTTCTCATCACTGCACAGATCTGTCTGAAAGCCTCAGT
TTCTGAGTGACCCAGGAACAGATCAGAAATGGAGCATGGCCTTGTCCTTTAATGGGGATGCAAATAAAGTTTGTGGGGTTAAAAGTTATA
AGACAGCAGTGATACCCCACTCTCTCCATTATTGTCCAGCGGGGTGACATAATGACAGGTTAAATATTTGTGATTCATTGATTAAATATT
ATTTAAAGAAATGTAAATTCACAATAAGGGTTGAAAATTATTTGGTTTCATCCATTGTCTCTTATTTCAGGACCAAGCAGCAAACTGCAG
TAGTTTGTGAAGGATTCTAATATGGGGTTCAGGAATAGCCTCTCAACGCTACTAATTCAGATCTCTCCCAGAGAACTACTGGATTTCCTC
ATAATTGACAAACATGAGTGACCACCTCTTTGGGTGGCTACTGTTAGAAATGGCTGTTGTCATGTTTTCTGGACTTTGCCAGCCAACAGA
TCCCTGCCAGGTTTTGGAAATACTTCTATTACCTCGCTGCTACTTTTCTGCAGGGATAAAACTTTTGAGGTGGCCAGACCCAGAACATCC
AAGGATTCCTGTTACAGTGCTACAGTATACACTGCTCATTTATCCTATTCTCATGTGCTTTCTTCTTTAGTAAGATTATTTTAAGAAAAT
AAGTGATATTTAAAGTCCAAAGAGGAATGATCACAGTTGTATAAGGGGTGTTTTCCCACTTGAACTCTGATGTCAGTCGACTGTGGGTCA
GAGCTACAACCATCTGTTTGGTTTGATGTTTTGGTGGTTTACTTACGGAGTGGGGATAGTGTGAGACCTAATTCCCTGTGCAAATGTCTC
TTATTCCAGAAATGTGCATTTTGTCATCTATAAGCAAGAAATATGGGCATAGCAGCTCTTGGTTTAAAGTTTGCCATAACCTGTTCATGT
TTGTTTTAAGCTCAGGTAAAGATAACCTCCTCTTTCTATGACTCCAGTTTCCATTCAGGTTATAGTATTATTCAATAGTTGATTTTCTTT
TTAAGCTGGGCAATAAATTGATGTTTCCAGATGGTAACATGGGAGAGGGCATATAGGATAAAGATGAGCAAATTCTACCCTAAAAATGTT
CTAGTAGTTCACAGGAAGAAGATGAGGTTTAATAACTTTCAAGGTAATTCTAGATTGACATTTTGAGGGGAAAATGGGCTCTTGTTCTAG
TTGAAGTGAGCAGAGAAGGCTATAAATTAATATGTAACTTACAGCATTCCAGAGGTTAAAAATAACTGATGCAGATGTACTTCTTCAGTG
TGATTCTTCAGATCAAACTTTTACTTTTGGCATAGTTAATTTCAGAAAAATGTGCTGTATGTGTGTGTGTATGAGGGTTGGTCTTGCTGA
TCCTTCAGTTAGCTCTAAATTCTGGCAACTCCTTGTAATTCCAATGTATTTGATACATGAACAATCATGTTGAATGCATTTGTGATCTGG
GAGACTTCCTCGTCTTCCAGGGAAGGAAGGATGTGCAGCCCCTGAAGGCATGAAACTCCCAGTGTGTACGGAGCCAGTGGAATATGGGAT
ACCCATACCTTACCAGGCGCTGGTTCCTTCTGCTCACAATAACATCTGCCCAAAGAGGGAGTGGGAAGAACGCTTAGCTCTTTCACTAGT
ATGGATTTGAGTTCATGGTCACTATTTTTACCCACCTGCCTTTGTTAAAAATCACTTTGAGTAGAATAGCACTGGAGGAACATATTTAGC
ACCTAATATTAATATTTAGTAGTCCATTGATAAATTTGCCAGCATATGTTCTAGCCTCTGGGGGGAAACCAGGACCACTTTTGTCTGTGG
CTTAAACAGTTCAGTTGCTATATCTGTTGGGTATGCCGGGGGTGGATGAGTGTGGCATTCCGTGAAGAGGAAGGTGGTAAGTAAGGTTTC
CCTTCTACTGCCTTCTTAAGTTGCAGGAGGGAGCTTTTCTCCTCCCCTCTGGTTGGGAGCACTGAGGACAGTGAGGAGGGCTTTTACCTT
GTTAATCCTTTCCTTATTTAGCTAGCTTTCCTTTTTGTCTAGGGCTTCCTCTTGAGACCCTCTTCCATCCATTGGGCCTTTGAAAGGACT
AATCAGACACACACACACACACACACACACACACACACACTCGCATACTCATGCACATTTTCCTTCATTTCCAGATCCTTTATTTCAGAG
CAGCCCATTTTCCTCTGGATTCATTGATGAATACAAGTACCCACACCTTTGGCCAGTAATGTCAGTTACCTGCTGCAGGTTCTGTGTATG
AGGCCTTCATGAACGGTTACCTTCTCCATACACTAGGGAAGCATTTGTCAGACTCTGCAGACTGGGTTCTAGAGAGGCAGAGTCTTTAAG
AGTATTCATTTCTTCTGGAAGGTGGAGCTTTACCCAAAGTGGAAGTTAGCCTTGCTCAAAGATGTGTTTTGTGGTAGGTGGTAAAAATAA
ATAAATAAATAAATAATAAAAAAAGAAACATGTATTGGAGGTAATTTGACACTGCTGCTGGCAGTAGTTCTCTATTCACCATTTTAAAGC
CCATTCAGGTTCTCTCTTCCTGAAAAGAACTGATTGCTGTGTTTACATGAAATGACATTGGAGTCAGATGGTCTGTTTTAAAGATTTCCA
TGACAGCCTCTTTTCCTGAGTTGGAGAGATTGGAGGTGGTCTATCCGTACGATGTGGAATCAAACGGTGGGTTTCTTAGTAGCTAAAGAA
GCCATGTACTTCTAGTGTGTTTCTCAGAATATCAACTCATGTTCTTCAGATGCTTTTCTTTTTTTAATGGTGAGGGAAAAGGTATAATTT
GGGATTCCACAGTGCCTTGCATATAGTAGGCGCCCAGTAAATACTTGTTGAAGCAAACCAAGTTTCCCAAGTCCTCATCTCTTATAGTGA
CCAAGACATCTTTCTCCTCTGAAGGGCTTGGCAGTTGTGGCTAAAAAATAAGCAGTATCATTATTTGCTTGAAATCATATATACAGTTTG
TATGAATTTCAGTATGTTGCCAAGACATGATTTTTTCTTATTGTATTTTCTGTAAATATTTCTGGCACTGAACTGTAAAGTAAAGGCAAA
GTGTAAATATGAAGGCGTGCCCGTGCCCCTTGCCTCCTGTGTTTCATCTTCGTCGGTTAGGGAAGAAGGTCCAGAGGTTTGTTTGTATTT

>69092_69092_1_PRPS2-RALGAPB_PRPS2_chrX_12817509_ENST00000380668_RALGAPB_chr20_37198531_ENST00000262879_length(amino acids)=278AA_BP=102
MPNIVLFSGSSHQDLSQRVADRLGLELGKVVTKKFSNQETSVEIGESVRGEDVYIIQSGCGEINDNLMELLIMINACKIASSSRVTAVIP
CFPYARQDKKDKLSPSSRMRKLPQGRPVPPLGPETRVSVVWVERYDDIENFPLSELMTEISTGVETTANSSTSLRSTTLEKEVPVIFIHP
LNTGLFRIKIQGATGKFNMVIPLVDGMIVSRRALGFLVRQTVINICRRKRLESDSYSPPHVRRKQKITDIVNKYRNKQLEPEFYTSLFQE

--------------------------------------------------------------
>69092_69092_2_PRPS2-RALGAPB_PRPS2_chrX_12817509_ENST00000380668_RALGAPB_chr20_37198531_ENST00000397038_length(transcript)=4859nt_BP=434nt
CCTCCCCTTCCCTACATCTAGCCGCCGCGCTTTCCCGCTCCCGCAGCAGCAGCCTCCCGCGTCGCTGTCGCTGTTGCCTCCGCCACCTCC
TCCGCCGCCGCGCGCCCCTCGGAGTTCCGCGCCCCACCATGCCCAACATCGTGCTGTTCAGCGGCAGCTCGCATCAGGACCTGTCCCAGC
GCGTGGCCGACCGCCTGGGCCTGGAGCTGGGCAAGGTGGTCACGAAGAAGTTCAGCAACCAGGAGACCAGCGTGGAGATTGGTGAAAGCG
TGAGAGGGGAAGATGTCTACATCATCCAGAGCGGCTGCGGGGAAATTAACGACAACCTGATGGAACTCCTCATCATGATCAATGCCTGCA
AGATTGCGTCATCATCCAGAGTAACTGCCGTGATCCCGTGTTTCCCATACGCCCGACAAGATAAAAAGGACAAGCTCAGTCCCAGTTCCA
GAATGAGGAAGCTGCCTCAGGGTCGCCCTGTTCCTCCCCTTGGACCTGAGACAAGAGTTTCTGTAGTCTGGGTGGAACGCTATGATGATA
TAGAAAACTTTCCCCTCTCAGAGCTGATGACAGAGATCAGTACTGGTGTGGAAACTACTGCAAATAGTAGCACTTCACTGAGATCTACAA
CTCTTGAAAAAGAAGTTCCTGTCATCTTCATCCACCCTTTAAACACTGGATTATTCCGGATAAAAATTCAAGGAGCCACTGGAAAATTTA
ATATGGTCATCCCTCTTGTGGATGGGATGATTGTCAGCAGGCGAGCTCTTGGCTTTCTGGTGAGGCAGACTGTAATTAACATTTGTAGAA
GAAAGAGACTGGAAAGTGACTCCTACAGTCCCCCCCATGTCCGCCGGAAACAGAAAATCACCGACATTGTCAACAAGTACCGGAACAAGC
AGCTGGAGCCAGAGTTTTATACTTCACTTTTCCAGGAGGTTGGACTCAAGAACTGCAGTTCTTAGACCACTGAATTTCTAAGACTGTTGA
ACTCCAGTTTGGGAACTATAACACAGCAGAACAGTTTGATAGGTGATCACTGTAAAAATAAAAACAAATCACTCCCAAGAGCTTACTGTT
TAATCACCAGAATAGAAGAAACACATTATAACCCATTTGATAGAAGACTTTGGGCTATCTAGTGAAATGGGCTCCCAGACACAATCACAC
TCCTGCTGATAATGATGATATACATTTTAGCCATAAACTTTCTTTTAAAAGTGACAATTTTAGTTAAACATAAGCCTTTTGAGGAGAAAG
GCTTTTATGCATCTCAGTTAAACACGTGCATTGGTAGTATCAACAAATTTGCAATATAGAAGTTGAAGATAGTTTTTTACCTCACTTTTT
AGGAGGTTGTATTCAAAATTAAAATCTCAGAATCTTACAGGACATTTAAAGACTCATGTTGATAGCATGGAGGAGAAGGAAAGAAGTCAC
AGCCTTCTACTCAGTTGTAGGTCTTCTTGTCATCCAGCTGTCACACTGACAAAAAGAAAAGATGATACATGTTTTTTGCTCAGATAAGAA
GCCTGACATTAAAAGATGTCATATTTTTTTCTCCACATTTCAAAAAGTTGTCCTTCTCATCACTGCACAGATCTGTCTGAAAGCCTCAGT
TTCTGAGTGACCCAGGAACAGATCAGAAATGGAGCATGGCCTTGTCCTTTAATGGGGATGCAAATAAAGTTTGTGGGGTTAAAAGTTATA
AGACAGCAGTGATACCCCACTCTCTCCATTATTGTCCAGCGGGGTGACATAATGACAGGTTAAATATTTGTGATTCATTGATTAAATATT
ATTTAAAGAAATGTAAATTCACAATAAGGGTTGAAAATTATTTGGTTTCATCCATTGTCTCTTATTTCAGGACCAAGCAGCAAACTGCAG
TAGTTTGTGAAGGATTCTAATATGGGGTTCAGGAATAGCCTCTCAACGCTACTAATTCAGATCTCTCCCAGAGAACTACTGGATTTCCTC
ATAATTGACAAACATGAGTGACCACCTCTTTGGGTGGCTACTGTTAGAAATGGCTGTTGTCATGTTTTCTGGACTTTGCCAGCCAACAGA
TCCCTGCCAGGTTTTGGAAATACTTCTATTACCTCGCTGCTACTTTTCTGCAGGGATAAAACTTTTGAGGTGGCCAGACCCAGAACATCC
AAGGATTCCTGTTACAGTGCTACAGTATACACTGCTCATTTATCCTATTCTCATGTGCTTTCTTCTTTAGTAAGATTATTTTAAGAAAAT
AAGTGATATTTAAAGTCCAAAGAGGAATGATCACAGTTGTATAAGGGGTGTTTTCCCACTTGAACTCTGATGTCAGTCGACTGTGGGTCA
GAGCTACAACCATCTGTTTGGTTTGATGTTTTGGTGGTTTACTTACGGAGTGGGGATAGTGTGAGACCTAATTCCCTGTGCAAATGTCTC
TTATTCCAGAAATGTGCATTTTGTCATCTATAAGCAAGAAATATGGGCATAGCAGCTCTTGGTTTAAAGTTTGCCATAACCTGTTCATGT
TTGTTTTAAGCTCAGGTAAAGATAACCTCCTCTTTCTATGACTCCAGTTTCCATTCAGGTTATAGTATTATTCAATAGTTGATTTTCTTT
TTAAGCTGGGCAATAAATTGATGTTTCCAGATGGTAACATGGGAGAGGGCATATAGGATAAAGATGAGCAAATTCTACCCTAAAAATGTT
CTAGTAGTTCACAGGAAGAAGATGAGGTTTAATAACTTTCAAGGTAATTCTAGATTGACATTTTGAGGGGAAAATGGGCTCTTGTTCTAG
TTGAAGTGAGCAGAGAAGGCTATAAATTAATATGTAACTTACAGCATTCCAGAGGTTAAAAATAACTGATGCAGATGTACTTCTTCAGTG
TGATTCTTCAGATCAAACTTTTACTTTTGGCATAGTTAATTTCAGAAAAATGTGCTGTATGTGTGTGTGTATGAGGGTTGGTCTTGCTGA
TCCTTCAGTTAGCTCTAAATTCTGGCAACTCCTTGTAATTCCAATGTATTTGATACATGAACAATCATGTTGAATGCATTTGTGATCTGG
GAGACTTCCTCGTCTTCCAGGGAAGGAAGGATGTGCAGCCCCTGAAGGCATGAAACTCCCAGTGTGTACGGAGCCAGTGGAATATGGGAT
ACCCATACCTTACCAGGCGCTGGTTCCTTCTGCTCACAATAACATCTGCCCAAAGAGGGAGTGGGAAGAACGCTTAGCTCTTTCACTAGT
ATGGATTTGAGTTCATGGTCACTATTTTTACCCACCTGCCTTTGTTAAAAATCACTTTGAGTAGAATAGCACTGGAGGAACATATTTAGC
ACCTAATATTAATATTTAGTAGTCCATTGATAAATTTGCCAGCATATGTTCTAGCCTCTGGGGGGAAACCAGGACCACTTTTGTCTGTGG
CTTAAACAGTTCAGTTGCTATATCTGTTGGGTATGCCGGGGGTGGATGAGTGTGGCATTCCGTGAAGAGGAAGGTGGTAAGTAAGGTTTC
CCTTCTACTGCCTTCTTAAGTTGCAGGAGGGAGCTTTTCTCCTCCCCTCTGGTTGGGAGCACTGAGGACAGTGAGGAGGGCTTTTACCTT
GTTAATCCTTTCCTTATTTAGCTAGCTTTCCTTTTTGTCTAGGGCTTCCTCTTGAGACCCTCTTCCATCCATTGGGCCTTTGAAAGGACT
AATCAGACACACACACACACACACACACACACACACACACTCGCATACTCATGCACATTTTCCTTCATTTCCAGATCCTTTATTTCAGAG
CAGCCCATTTTCCTCTGGATTCATTGATGAATACAAGTACCCACACCTTTGGCCAGTAATGTCAGTTACCTGCTGCAGGTTCTGTGTATG
AGGCCTTCATGAACGGTTACCTTCTCCATACACTAGGGAAGCATTTGTCAGACTCTGCAGACTGGGTTCTAGAGAGGCAGAGTCTTTAAG
AGTATTCATTTCTTCTGGAAGGTGGAGCTTTACCCAAAGTGGAAGTTAGCCTTGCTCAAAGATGTGTTTTGTGGTAGGTGGTAAAAATAA
ATAAATAAATAAATAATAAAAAAAGAAACATGTATTGGAGGTAATTTGACACTGCTGCTGGCAGTAGTTCTCTATTCACCATTTTAAAGC
CCATTCAGGTTCTCTCTTCCTGAAAAGAACTGATTGCTGTGTTTACATGAAATGACATTGGAGTCAGATGGTCTGTTTTAAAGATTTCCA
TGACAGCCTCTTTTCCTGAGTTGGAGAGATTGGAGGTGGTCTATCCGTACGATGTGGAATCAAACGGTGGGTTTCTTAGTAGCTAAAGAA
GCCATGTACTTCTAGTGTGTTTCTCAGAATATCAACTCATGTTCTTCAGATGCTTTTCTTTTTTTAATGGTGAGGGAAAAGGTATAATTT
GGGATTCCACAGTGCCTTGCATATAGTAGGCGCCCAGTAAATACTTGTTGAAGCAAACCAAGTTTCCCAAGTCCTCATCTCTTATAGTGA
CCAAGACATCTTTCTCCTCTGAAGGGCTTGGCAGTTGTGGCTAAAAAATAAGCAGTATCATTATTTGCTTGAAATCATATATACAGTTTG
TATGAATTTCAGTATGTTGCCAAGACATGATTTTTTCTTATTGTATTTTCTGTAAATATTTCTGGCACTGAACTGTAAAGTAAAGGCAAA
GTGTAAATATGAAGGCGTGCCCGTGCCCCTTGCCTCCTGTGTTTCATCTTCGTCGGTTAGGGAAGAAGGTCCAGAGGTTTGTTTGTATTT

>69092_69092_2_PRPS2-RALGAPB_PRPS2_chrX_12817509_ENST00000380668_RALGAPB_chr20_37198531_ENST00000397038_length(amino acids)=278AA_BP=102
MPNIVLFSGSSHQDLSQRVADRLGLELGKVVTKKFSNQETSVEIGESVRGEDVYIIQSGCGEINDNLMELLIMINACKIASSSRVTAVIP
CFPYARQDKKDKLSPSSRMRKLPQGRPVPPLGPETRVSVVWVERYDDIENFPLSELMTEISTGVETTANSSTSLRSTTLEKEVPVIFIHP
LNTGLFRIKIQGATGKFNMVIPLVDGMIVSRRALGFLVRQTVINICRRKRLESDSYSPPHVRRKQKITDIVNKYRNKQLEPEFYTSLFQE

--------------------------------------------------------------
>69092_69092_3_PRPS2-RALGAPB_PRPS2_chrX_12817509_ENST00000380668_RALGAPB_chr20_37198531_ENST00000397042_length(transcript)=4857nt_BP=434nt
CCTCCCCTTCCCTACATCTAGCCGCCGCGCTTTCCCGCTCCCGCAGCAGCAGCCTCCCGCGTCGCTGTCGCTGTTGCCTCCGCCACCTCC
TCCGCCGCCGCGCGCCCCTCGGAGTTCCGCGCCCCACCATGCCCAACATCGTGCTGTTCAGCGGCAGCTCGCATCAGGACCTGTCCCAGC
GCGTGGCCGACCGCCTGGGCCTGGAGCTGGGCAAGGTGGTCACGAAGAAGTTCAGCAACCAGGAGACCAGCGTGGAGATTGGTGAAAGCG
TGAGAGGGGAAGATGTCTACATCATCCAGAGCGGCTGCGGGGAAATTAACGACAACCTGATGGAACTCCTCATCATGATCAATGCCTGCA
AGATTGCGTCATCATCCAGAGTAACTGCCGTGATCCCGTGTTTCCCATACGCCCGACAAGATAAAAAGGACAAGCTCAGTCCCAGTTCCA
GAATGAGGAAGCTGCCTCAGGGTCGCCCTGTTCCTCCCCTTGGACCTGAGACAAGAGTTTCTGTAGTCTGGGTGGAACGCTATGATGATA
TAGAAAACTTTCCCCTCTCAGAGCTGATGACAGAGATCAGTACTGGTGTGGAAACTACTGCAAATAGTAGCACTTCACTGAGATCTACAA
CTCTTGAAAAAGAAGTTCCTGTCATCTTCATCCACCCTTTAAACACTGGATTATTCCGGATAAAAATTCAAGGAGCCACTGGAAAATTTA
ATATGGTCATCCCTCTTGTGGATGGGATGATTGTCAGCAGGCGAGCTCTTGGCTTTCTGGTGAGGCAGACTGTAATTAACATTTGTAGAA
GAAAGAGACTGGAAAGTGACTCCTACAGTCCCCCCCATGTCCGCCGGAAACAGAAAATCACCGACATTGTCAACAAGTACCGGAACAAGC
AGCTGGAGCCAGAGTTTTATACTTCACTTTTCCAGGAGGTTGGACTCAAGAACTGCAGTTCTTAGACCACTGAATTTCTAAGACTGTTGA
ACTCCAGTTTGGGAACTATAACACAGCAGAACAGTTTGATAGGTGATCACTGTAAAAATAAAAACAAATCACTCCCAAGAGCTTACTGTT
TAATCACCAGAATAGAAGAAACACATTATAACCCATTTGATAGAAGACTTTGGGCTATCTAGTGAAATGGGCTCCCAGACACAATCACAC
TCCTGCTGATAATGATGATATACATTTTAGCCATAAACTTTCTTTTAAAAGTGACAATTTTAGTTAAACATAAGCCTTTTGAGGAGAAAG
GCTTTTATGCATCTCAGTTAAACACGTGCATTGGTAGTATCAACAAATTTGCAATATAGAAGTTGAAGATAGTTTTTTACCTCACTTTTT
AGGAGGTTGTATTCAAAATTAAAATCTCAGAATCTTACAGGACATTTAAAGACTCATGTTGATAGCATGGAGGAGAAGGAAAGAAGTCAC
AGCCTTCTACTCAGTTGTAGGTCTTCTTGTCATCCAGCTGTCACACTGACAAAAAGAAAAGATGATACATGTTTTTTGCTCAGATAAGAA
GCCTGACATTAAAAGATGTCATATTTTTTTCTCCACATTTCAAAAAGTTGTCCTTCTCATCACTGCACAGATCTGTCTGAAAGCCTCAGT
TTCTGAGTGACCCAGGAACAGATCAGAAATGGAGCATGGCCTTGTCCTTTAATGGGGATGCAAATAAAGTTTGTGGGGTTAAAAGTTATA
AGACAGCAGTGATACCCCACTCTCTCCATTATTGTCCAGCGGGGTGACATAATGACAGGTTAAATATTTGTGATTCATTGATTAAATATT
ATTTAAAGAAATGTAAATTCACAATAAGGGTTGAAAATTATTTGGTTTCATCCATTGTCTCTTATTTCAGGACCAAGCAGCAAACTGCAG
TAGTTTGTGAAGGATTCTAATATGGGGTTCAGGAATAGCCTCTCAACGCTACTAATTCAGATCTCTCCCAGAGAACTACTGGATTTCCTC
ATAATTGACAAACATGAGTGACCACCTCTTTGGGTGGCTACTGTTAGAAATGGCTGTTGTCATGTTTTCTGGACTTTGCCAGCCAACAGA
TCCCTGCCAGGTTTTGGAAATACTTCTATTACCTCGCTGCTACTTTTCTGCAGGGATAAAACTTTTGAGGTGGCCAGACCCAGAACATCC
AAGGATTCCTGTTACAGTGCTACAGTATACACTGCTCATTTATCCTATTCTCATGTGCTTTCTTCTTTAGTAAGATTATTTTAAGAAAAT
AAGTGATATTTAAAGTCCAAAGAGGAATGATCACAGTTGTATAAGGGGTGTTTTCCCACTTGAACTCTGATGTCAGTCGACTGTGGGTCA
GAGCTACAACCATCTGTTTGGTTTGATGTTTTGGTGGTTTACTTACGGAGTGGGGATAGTGTGAGACCTAATTCCCTGTGCAAATGTCTC
TTATTCCAGAAATGTGCATTTTGTCATCTATAAGCAAGAAATATGGGCATAGCAGCTCTTGGTTTAAAGTTTGCCATAACCTGTTCATGT
TTGTTTTAAGCTCAGGTAAAGATAACCTCCTCTTTCTATGACTCCAGTTTCCATTCAGGTTATAGTATTATTCAATAGTTGATTTTCTTT
TTAAGCTGGGCAATAAATTGATGTTTCCAGATGGTAACATGGGAGAGGGCATATAGGATAAAGATGAGCAAATTCTACCCTAAAAATGTT
CTAGTAGTTCACAGGAAGAAGATGAGGTTTAATAACTTTCAAGGTAATTCTAGATTGACATTTTGAGGGGAAAATGGGCTCTTGTTCTAG
TTGAAGTGAGCAGAGAAGGCTATAAATTAATATGTAACTTACAGCATTCCAGAGGTTAAAAATAACTGATGCAGATGTACTTCTTCAGTG
TGATTCTTCAGATCAAACTTTTACTTTTGGCATAGTTAATTTCAGAAAAATGTGCTGTATGTGTGTGTGTATGAGGGTTGGTCTTGCTGA
TCCTTCAGTTAGCTCTAAATTCTGGCAACTCCTTGTAATTCCAATGTATTTGATACATGAACAATCATGTTGAATGCATTTGTGATCTGG
GAGACTTCCTCGTCTTCCAGGGAAGGAAGGATGTGCAGCCCCTGAAGGCATGAAACTCCCAGTGTGTACGGAGCCAGTGGAATATGGGAT
ACCCATACCTTACCAGGCGCTGGTTCCTTCTGCTCACAATAACATCTGCCCAAAGAGGGAGTGGGAAGAACGCTTAGCTCTTTCACTAGT
ATGGATTTGAGTTCATGGTCACTATTTTTACCCACCTGCCTTTGTTAAAAATCACTTTGAGTAGAATAGCACTGGAGGAACATATTTAGC
ACCTAATATTAATATTTAGTAGTCCATTGATAAATTTGCCAGCATATGTTCTAGCCTCTGGGGGGAAACCAGGACCACTTTTGTCTGTGG
CTTAAACAGTTCAGTTGCTATATCTGTTGGGTATGCCGGGGGTGGATGAGTGTGGCATTCCGTGAAGAGGAAGGTGGTAAGTAAGGTTTC
CCTTCTACTGCCTTCTTAAGTTGCAGGAGGGAGCTTTTCTCCTCCCCTCTGGTTGGGAGCACTGAGGACAGTGAGGAGGGCTTTTACCTT
GTTAATCCTTTCCTTATTTAGCTAGCTTTCCTTTTTGTCTAGGGCTTCCTCTTGAGACCCTCTTCCATCCATTGGGCCTTTGAAAGGACT
AATCAGACACACACACACACACACACACACACACACACACTCGCATACTCATGCACATTTTCCTTCATTTCCAGATCCTTTATTTCAGAG
CAGCCCATTTTCCTCTGGATTCATTGATGAATACAAGTACCCACACCTTTGGCCAGTAATGTCAGTTACCTGCTGCAGGTTCTGTGTATG
AGGCCTTCATGAACGGTTACCTTCTCCATACACTAGGGAAGCATTTGTCAGACTCTGCAGACTGGGTTCTAGAGAGGCAGAGTCTTTAAG
AGTATTCATTTCTTCTGGAAGGTGGAGCTTTACCCAAAGTGGAAGTTAGCCTTGCTCAAAGATGTGTTTTGTGGTAGGTGGTAAAAATAA
ATAAATAAATAAATAATAAAAAAAGAAACATGTATTGGAGGTAATTTGACACTGCTGCTGGCAGTAGTTCTCTATTCACCATTTTAAAGC
CCATTCAGGTTCTCTCTTCCTGAAAAGAACTGATTGCTGTGTTTACATGAAATGACATTGGAGTCAGATGGTCTGTTTTAAAGATTTCCA
TGACAGCCTCTTTTCCTGAGTTGGAGAGATTGGAGGTGGTCTATCCGTACGATGTGGAATCAAACGGTGGGTTTCTTAGTAGCTAAAGAA
GCCATGTACTTCTAGTGTGTTTCTCAGAATATCAACTCATGTTCTTCAGATGCTTTTCTTTTTTTAATGGTGAGGGAAAAGGTATAATTT
GGGATTCCACAGTGCCTTGCATATAGTAGGCGCCCAGTAAATACTTGTTGAAGCAAACCAAGTTTCCCAAGTCCTCATCTCTTATAGTGA
CCAAGACATCTTTCTCCTCTGAAGGGCTTGGCAGTTGTGGCTAAAAAATAAGCAGTATCATTATTTGCTTGAAATCATATATACAGTTTG
TATGAATTTCAGTATGTTGCCAAGACATGATTTTTTCTTATTGTATTTTCTGTAAATATTTCTGGCACTGAACTGTAAAGTAAAGGCAAA
GTGTAAATATGAAGGCGTGCCCGTGCCCCTTGCCTCCTGTGTTTCATCTTCGTCGGTTAGGGAAGAAGGTCCAGAGGTTTGTTTGTATTT

>69092_69092_3_PRPS2-RALGAPB_PRPS2_chrX_12817509_ENST00000380668_RALGAPB_chr20_37198531_ENST00000397042_length(amino acids)=278AA_BP=102
MPNIVLFSGSSHQDLSQRVADRLGLELGKVVTKKFSNQETSVEIGESVRGEDVYIIQSGCGEINDNLMELLIMINACKIASSSRVTAVIP
CFPYARQDKKDKLSPSSRMRKLPQGRPVPPLGPETRVSVVWVERYDDIENFPLSELMTEISTGVETTANSSTSLRSTTLEKEVPVIFIHP
LNTGLFRIKIQGATGKFNMVIPLVDGMIVSRRALGFLVRQTVINICRRKRLESDSYSPPHVRRKQKITDIVNKYRNKQLEPEFYTSLFQE

--------------------------------------------------------------
>69092_69092_4_PRPS2-RALGAPB_PRPS2_chrX_12817509_ENST00000398491_RALGAPB_chr20_37198531_ENST00000262879_length(transcript)=4646nt_BP=223nt
GCTCCCGCAGCAGCAGCCTCCCGCGTCGCTGTCGCTGTTGCCTCCGCCACCTCCTCCGCCGCCGCGCGCCCCTCGGAGTTCCGCGCCCCA
CCATGCCCAACATCGTGCTGTTCAGCGGCAGCTCGCATCAGGACCTGTCCCAGCGCGTGGCCGACCGCCTGGGCCTGGAGCTGGGCAAGG
TGGTCACGAAGAAGTTCAGCAACCAGGAGACCAGGTAGGAGAGCTCAGTCCCAGTTCCAGAATGAGGAAGCTGCCTCAGGGTCGCCCTGT
TCCTCCCCTTGGACCTGAGACAAGAGTTTCTGTAGTCTGGGTGGAACGCTATGATGATATAGAAAACTTTCCCCTCTCAGAGCTGATGAC
AGAGATCAGTACTGGTGTGGAAACTACTGCAAATAGTAGCACTTCACTGAGATCTACAACTCTTGAAAAAGAAGTTCCTGTCATCTTCAT
CCACCCTTTAAACACTGGATTATTCCGGATAAAAATTCAAGGAGCCACTGGAAAATTTAATATGGTCATCCCTCTTGTGGATGGGATGAT
TGTCAGCAGGCGAGCTCTTGGCTTTCTGGTGAGGCAGACTGTAATTAACATTTGTAGAAGAAAGAGACTGGAAAGTGACTCCTACAGTCC
CCCCCATGTCCGCCGGAAACAGAAAATCACCGACATTGTCAACAAGTACCGGAACAAGCAGCTGGAGCCAGAGTTTTATACTTCACTTTT
CCAGGAGGTTGGACTCAAGAACTGCAGTTCTTAGACCACTGAATTTCTAAGACTGTTGAACTCCAGTTTGGGAACTATAACACAGCAGAA
CAGTTTGATAGGTGATCACTGTAAAAATAAAAACAAATCACTCCCAAGAGCTTACTGTTTAATCACCAGAATAGAAGAAACACATTATAA
CCCATTTGATAGAAGACTTTGGGCTATCTAGTGAAATGGGCTCCCAGACACAATCACACTCCTGCTGATAATGATGATATACATTTTAGC
CATAAACTTTCTTTTAAAAGTGACAATTTTAGTTAAACATAAGCCTTTTGAGGAGAAAGGCTTTTATGCATCTCAGTTAAACACGTGCAT
TGGTAGTATCAACAAATTTGCAATATAGAAGTTGAAGATAGTTTTTTACCTCACTTTTTAGGAGGTTGTATTCAAAATTAAAATCTCAGA
ATCTTACAGGACATTTAAAGACTCATGTTGATAGCATGGAGGAGAAGGAAAGAAGTCACAGCCTTCTACTCAGTTGTAGGTCTTCTTGTC
ATCCAGCTGTCACACTGACAAAAAGAAAAGATGATACATGTTTTTTGCTCAGATAAGAAGCCTGACATTAAAAGATGTCATATTTTTTTC
TCCACATTTCAAAAAGTTGTCCTTCTCATCACTGCACAGATCTGTCTGAAAGCCTCAGTTTCTGAGTGACCCAGGAACAGATCAGAAATG
GAGCATGGCCTTGTCCTTTAATGGGGATGCAAATAAAGTTTGTGGGGTTAAAAGTTATAAGACAGCAGTGATACCCCACTCTCTCCATTA
TTGTCCAGCGGGGTGACATAATGACAGGTTAAATATTTGTGATTCATTGATTAAATATTATTTAAAGAAATGTAAATTCACAATAAGGGT
TGAAAATTATTTGGTTTCATCCATTGTCTCTTATTTCAGGACCAAGCAGCAAACTGCAGTAGTTTGTGAAGGATTCTAATATGGGGTTCA
GGAATAGCCTCTCAACGCTACTAATTCAGATCTCTCCCAGAGAACTACTGGATTTCCTCATAATTGACAAACATGAGTGACCACCTCTTT
GGGTGGCTACTGTTAGAAATGGCTGTTGTCATGTTTTCTGGACTTTGCCAGCCAACAGATCCCTGCCAGGTTTTGGAAATACTTCTATTA
CCTCGCTGCTACTTTTCTGCAGGGATAAAACTTTTGAGGTGGCCAGACCCAGAACATCCAAGGATTCCTGTTACAGTGCTACAGTATACA
CTGCTCATTTATCCTATTCTCATGTGCTTTCTTCTTTAGTAAGATTATTTTAAGAAAATAAGTGATATTTAAAGTCCAAAGAGGAATGAT
CACAGTTGTATAAGGGGTGTTTTCCCACTTGAACTCTGATGTCAGTCGACTGTGGGTCAGAGCTACAACCATCTGTTTGGTTTGATGTTT
TGGTGGTTTACTTACGGAGTGGGGATAGTGTGAGACCTAATTCCCTGTGCAAATGTCTCTTATTCCAGAAATGTGCATTTTGTCATCTAT
AAGCAAGAAATATGGGCATAGCAGCTCTTGGTTTAAAGTTTGCCATAACCTGTTCATGTTTGTTTTAAGCTCAGGTAAAGATAACCTCCT
CTTTCTATGACTCCAGTTTCCATTCAGGTTATAGTATTATTCAATAGTTGATTTTCTTTTTAAGCTGGGCAATAAATTGATGTTTCCAGA
TGGTAACATGGGAGAGGGCATATAGGATAAAGATGAGCAAATTCTACCCTAAAAATGTTCTAGTAGTTCACAGGAAGAAGATGAGGTTTA
ATAACTTTCAAGGTAATTCTAGATTGACATTTTGAGGGGAAAATGGGCTCTTGTTCTAGTTGAAGTGAGCAGAGAAGGCTATAAATTAAT
ATGTAACTTACAGCATTCCAGAGGTTAAAAATAACTGATGCAGATGTACTTCTTCAGTGTGATTCTTCAGATCAAACTTTTACTTTTGGC
ATAGTTAATTTCAGAAAAATGTGCTGTATGTGTGTGTGTATGAGGGTTGGTCTTGCTGATCCTTCAGTTAGCTCTAAATTCTGGCAACTC
CTTGTAATTCCAATGTATTTGATACATGAACAATCATGTTGAATGCATTTGTGATCTGGGAGACTTCCTCGTCTTCCAGGGAAGGAAGGA
TGTGCAGCCCCTGAAGGCATGAAACTCCCAGTGTGTACGGAGCCAGTGGAATATGGGATACCCATACCTTACCAGGCGCTGGTTCCTTCT
GCTCACAATAACATCTGCCCAAAGAGGGAGTGGGAAGAACGCTTAGCTCTTTCACTAGTATGGATTTGAGTTCATGGTCACTATTTTTAC
CCACCTGCCTTTGTTAAAAATCACTTTGAGTAGAATAGCACTGGAGGAACATATTTAGCACCTAATATTAATATTTAGTAGTCCATTGAT
AAATTTGCCAGCATATGTTCTAGCCTCTGGGGGGAAACCAGGACCACTTTTGTCTGTGGCTTAAACAGTTCAGTTGCTATATCTGTTGGG
TATGCCGGGGGTGGATGAGTGTGGCATTCCGTGAAGAGGAAGGTGGTAAGTAAGGTTTCCCTTCTACTGCCTTCTTAAGTTGCAGGAGGG
AGCTTTTCTCCTCCCCTCTGGTTGGGAGCACTGAGGACAGTGAGGAGGGCTTTTACCTTGTTAATCCTTTCCTTATTTAGCTAGCTTTCC
TTTTTGTCTAGGGCTTCCTCTTGAGACCCTCTTCCATCCATTGGGCCTTTGAAAGGACTAATCAGACACACACACACACACACACACACA
CACACACACTCGCATACTCATGCACATTTTCCTTCATTTCCAGATCCTTTATTTCAGAGCAGCCCATTTTCCTCTGGATTCATTGATGAA
TACAAGTACCCACACCTTTGGCCAGTAATGTCAGTTACCTGCTGCAGGTTCTGTGTATGAGGCCTTCATGAACGGTTACCTTCTCCATAC
ACTAGGGAAGCATTTGTCAGACTCTGCAGACTGGGTTCTAGAGAGGCAGAGTCTTTAAGAGTATTCATTTCTTCTGGAAGGTGGAGCTTT
ACCCAAAGTGGAAGTTAGCCTTGCTCAAAGATGTGTTTTGTGGTAGGTGGTAAAAATAAATAAATAAATAAATAATAAAAAAAGAAACAT
GTATTGGAGGTAATTTGACACTGCTGCTGGCAGTAGTTCTCTATTCACCATTTTAAAGCCCATTCAGGTTCTCTCTTCCTGAAAAGAACT
GATTGCTGTGTTTACATGAAATGACATTGGAGTCAGATGGTCTGTTTTAAAGATTTCCATGACAGCCTCTTTTCCTGAGTTGGAGAGATT
GGAGGTGGTCTATCCGTACGATGTGGAATCAAACGGTGGGTTTCTTAGTAGCTAAAGAAGCCATGTACTTCTAGTGTGTTTCTCAGAATA
TCAACTCATGTTCTTCAGATGCTTTTCTTTTTTTAATGGTGAGGGAAAAGGTATAATTTGGGATTCCACAGTGCCTTGCATATAGTAGGC
GCCCAGTAAATACTTGTTGAAGCAAACCAAGTTTCCCAAGTCCTCATCTCTTATAGTGACCAAGACATCTTTCTCCTCTGAAGGGCTTGG
CAGTTGTGGCTAAAAAATAAGCAGTATCATTATTTGCTTGAAATCATATATACAGTTTGTATGAATTTCAGTATGTTGCCAAGACATGAT
TTTTTCTTATTGTATTTTCTGTAAATATTTCTGGCACTGAACTGTAAAGTAAAGGCAAAGTGTAAATATGAAGGCGTGCCCGTGCCCCTT
GCCTCCTGTGTTTCATCTTCGTCGGTTAGGGAAGAAGGTCCAGAGGTTTGTTTGTATTTATGCCGATCCTTTGTCCAGAAGAAGCCCATG

>69092_69092_4_PRPS2-RALGAPB_PRPS2_chrX_12817509_ENST00000398491_RALGAPB_chr20_37198531_ENST00000262879_length(amino acids)=241AA_BP=65
MSLLPPPPPPPPRAPRSSAPHHAQHRAVQRQLASGPVPARGRPPGPGAGQGGHEEVQQPGDQVGELSPSSRMRKLPQGRPVPPLGPETRV
SVVWVERYDDIENFPLSELMTEISTGVETTANSSTSLRSTTLEKEVPVIFIHPLNTGLFRIKIQGATGKFNMVIPLVDGMIVSRRALGFL

--------------------------------------------------------------
>69092_69092_5_PRPS2-RALGAPB_PRPS2_chrX_12817509_ENST00000398491_RALGAPB_chr20_37198531_ENST00000397038_length(transcript)=4648nt_BP=223nt
GCTCCCGCAGCAGCAGCCTCCCGCGTCGCTGTCGCTGTTGCCTCCGCCACCTCCTCCGCCGCCGCGCGCCCCTCGGAGTTCCGCGCCCCA
CCATGCCCAACATCGTGCTGTTCAGCGGCAGCTCGCATCAGGACCTGTCCCAGCGCGTGGCCGACCGCCTGGGCCTGGAGCTGGGCAAGG
TGGTCACGAAGAAGTTCAGCAACCAGGAGACCAGGTAGGAGAGCTCAGTCCCAGTTCCAGAATGAGGAAGCTGCCTCAGGGTCGCCCTGT
TCCTCCCCTTGGACCTGAGACAAGAGTTTCTGTAGTCTGGGTGGAACGCTATGATGATATAGAAAACTTTCCCCTCTCAGAGCTGATGAC
AGAGATCAGTACTGGTGTGGAAACTACTGCAAATAGTAGCACTTCACTGAGATCTACAACTCTTGAAAAAGAAGTTCCTGTCATCTTCAT
CCACCCTTTAAACACTGGATTATTCCGGATAAAAATTCAAGGAGCCACTGGAAAATTTAATATGGTCATCCCTCTTGTGGATGGGATGAT
TGTCAGCAGGCGAGCTCTTGGCTTTCTGGTGAGGCAGACTGTAATTAACATTTGTAGAAGAAAGAGACTGGAAAGTGACTCCTACAGTCC
CCCCCATGTCCGCCGGAAACAGAAAATCACCGACATTGTCAACAAGTACCGGAACAAGCAGCTGGAGCCAGAGTTTTATACTTCACTTTT
CCAGGAGGTTGGACTCAAGAACTGCAGTTCTTAGACCACTGAATTTCTAAGACTGTTGAACTCCAGTTTGGGAACTATAACACAGCAGAA
CAGTTTGATAGGTGATCACTGTAAAAATAAAAACAAATCACTCCCAAGAGCTTACTGTTTAATCACCAGAATAGAAGAAACACATTATAA
CCCATTTGATAGAAGACTTTGGGCTATCTAGTGAAATGGGCTCCCAGACACAATCACACTCCTGCTGATAATGATGATATACATTTTAGC
CATAAACTTTCTTTTAAAAGTGACAATTTTAGTTAAACATAAGCCTTTTGAGGAGAAAGGCTTTTATGCATCTCAGTTAAACACGTGCAT
TGGTAGTATCAACAAATTTGCAATATAGAAGTTGAAGATAGTTTTTTACCTCACTTTTTAGGAGGTTGTATTCAAAATTAAAATCTCAGA
ATCTTACAGGACATTTAAAGACTCATGTTGATAGCATGGAGGAGAAGGAAAGAAGTCACAGCCTTCTACTCAGTTGTAGGTCTTCTTGTC
ATCCAGCTGTCACACTGACAAAAAGAAAAGATGATACATGTTTTTTGCTCAGATAAGAAGCCTGACATTAAAAGATGTCATATTTTTTTC
TCCACATTTCAAAAAGTTGTCCTTCTCATCACTGCACAGATCTGTCTGAAAGCCTCAGTTTCTGAGTGACCCAGGAACAGATCAGAAATG
GAGCATGGCCTTGTCCTTTAATGGGGATGCAAATAAAGTTTGTGGGGTTAAAAGTTATAAGACAGCAGTGATACCCCACTCTCTCCATTA
TTGTCCAGCGGGGTGACATAATGACAGGTTAAATATTTGTGATTCATTGATTAAATATTATTTAAAGAAATGTAAATTCACAATAAGGGT
TGAAAATTATTTGGTTTCATCCATTGTCTCTTATTTCAGGACCAAGCAGCAAACTGCAGTAGTTTGTGAAGGATTCTAATATGGGGTTCA
GGAATAGCCTCTCAACGCTACTAATTCAGATCTCTCCCAGAGAACTACTGGATTTCCTCATAATTGACAAACATGAGTGACCACCTCTTT
GGGTGGCTACTGTTAGAAATGGCTGTTGTCATGTTTTCTGGACTTTGCCAGCCAACAGATCCCTGCCAGGTTTTGGAAATACTTCTATTA
CCTCGCTGCTACTTTTCTGCAGGGATAAAACTTTTGAGGTGGCCAGACCCAGAACATCCAAGGATTCCTGTTACAGTGCTACAGTATACA
CTGCTCATTTATCCTATTCTCATGTGCTTTCTTCTTTAGTAAGATTATTTTAAGAAAATAAGTGATATTTAAAGTCCAAAGAGGAATGAT
CACAGTTGTATAAGGGGTGTTTTCCCACTTGAACTCTGATGTCAGTCGACTGTGGGTCAGAGCTACAACCATCTGTTTGGTTTGATGTTT
TGGTGGTTTACTTACGGAGTGGGGATAGTGTGAGACCTAATTCCCTGTGCAAATGTCTCTTATTCCAGAAATGTGCATTTTGTCATCTAT
AAGCAAGAAATATGGGCATAGCAGCTCTTGGTTTAAAGTTTGCCATAACCTGTTCATGTTTGTTTTAAGCTCAGGTAAAGATAACCTCCT
CTTTCTATGACTCCAGTTTCCATTCAGGTTATAGTATTATTCAATAGTTGATTTTCTTTTTAAGCTGGGCAATAAATTGATGTTTCCAGA
TGGTAACATGGGAGAGGGCATATAGGATAAAGATGAGCAAATTCTACCCTAAAAATGTTCTAGTAGTTCACAGGAAGAAGATGAGGTTTA
ATAACTTTCAAGGTAATTCTAGATTGACATTTTGAGGGGAAAATGGGCTCTTGTTCTAGTTGAAGTGAGCAGAGAAGGCTATAAATTAAT
ATGTAACTTACAGCATTCCAGAGGTTAAAAATAACTGATGCAGATGTACTTCTTCAGTGTGATTCTTCAGATCAAACTTTTACTTTTGGC
ATAGTTAATTTCAGAAAAATGTGCTGTATGTGTGTGTGTATGAGGGTTGGTCTTGCTGATCCTTCAGTTAGCTCTAAATTCTGGCAACTC
CTTGTAATTCCAATGTATTTGATACATGAACAATCATGTTGAATGCATTTGTGATCTGGGAGACTTCCTCGTCTTCCAGGGAAGGAAGGA
TGTGCAGCCCCTGAAGGCATGAAACTCCCAGTGTGTACGGAGCCAGTGGAATATGGGATACCCATACCTTACCAGGCGCTGGTTCCTTCT
GCTCACAATAACATCTGCCCAAAGAGGGAGTGGGAAGAACGCTTAGCTCTTTCACTAGTATGGATTTGAGTTCATGGTCACTATTTTTAC
CCACCTGCCTTTGTTAAAAATCACTTTGAGTAGAATAGCACTGGAGGAACATATTTAGCACCTAATATTAATATTTAGTAGTCCATTGAT
AAATTTGCCAGCATATGTTCTAGCCTCTGGGGGGAAACCAGGACCACTTTTGTCTGTGGCTTAAACAGTTCAGTTGCTATATCTGTTGGG
TATGCCGGGGGTGGATGAGTGTGGCATTCCGTGAAGAGGAAGGTGGTAAGTAAGGTTTCCCTTCTACTGCCTTCTTAAGTTGCAGGAGGG
AGCTTTTCTCCTCCCCTCTGGTTGGGAGCACTGAGGACAGTGAGGAGGGCTTTTACCTTGTTAATCCTTTCCTTATTTAGCTAGCTTTCC
TTTTTGTCTAGGGCTTCCTCTTGAGACCCTCTTCCATCCATTGGGCCTTTGAAAGGACTAATCAGACACACACACACACACACACACACA
CACACACACTCGCATACTCATGCACATTTTCCTTCATTTCCAGATCCTTTATTTCAGAGCAGCCCATTTTCCTCTGGATTCATTGATGAA
TACAAGTACCCACACCTTTGGCCAGTAATGTCAGTTACCTGCTGCAGGTTCTGTGTATGAGGCCTTCATGAACGGTTACCTTCTCCATAC
ACTAGGGAAGCATTTGTCAGACTCTGCAGACTGGGTTCTAGAGAGGCAGAGTCTTTAAGAGTATTCATTTCTTCTGGAAGGTGGAGCTTT
ACCCAAAGTGGAAGTTAGCCTTGCTCAAAGATGTGTTTTGTGGTAGGTGGTAAAAATAAATAAATAAATAAATAATAAAAAAAGAAACAT
GTATTGGAGGTAATTTGACACTGCTGCTGGCAGTAGTTCTCTATTCACCATTTTAAAGCCCATTCAGGTTCTCTCTTCCTGAAAAGAACT
GATTGCTGTGTTTACATGAAATGACATTGGAGTCAGATGGTCTGTTTTAAAGATTTCCATGACAGCCTCTTTTCCTGAGTTGGAGAGATT
GGAGGTGGTCTATCCGTACGATGTGGAATCAAACGGTGGGTTTCTTAGTAGCTAAAGAAGCCATGTACTTCTAGTGTGTTTCTCAGAATA
TCAACTCATGTTCTTCAGATGCTTTTCTTTTTTTAATGGTGAGGGAAAAGGTATAATTTGGGATTCCACAGTGCCTTGCATATAGTAGGC
GCCCAGTAAATACTTGTTGAAGCAAACCAAGTTTCCCAAGTCCTCATCTCTTATAGTGACCAAGACATCTTTCTCCTCTGAAGGGCTTGG
CAGTTGTGGCTAAAAAATAAGCAGTATCATTATTTGCTTGAAATCATATATACAGTTTGTATGAATTTCAGTATGTTGCCAAGACATGAT
TTTTTCTTATTGTATTTTCTGTAAATATTTCTGGCACTGAACTGTAAAGTAAAGGCAAAGTGTAAATATGAAGGCGTGCCCGTGCCCCTT
GCCTCCTGTGTTTCATCTTCGTCGGTTAGGGAAGAAGGTCCAGAGGTTTGTTTGTATTTATGCCGATCCTTTGTCCAGAAGAAGCCCATG

>69092_69092_5_PRPS2-RALGAPB_PRPS2_chrX_12817509_ENST00000398491_RALGAPB_chr20_37198531_ENST00000397038_length(amino acids)=241AA_BP=65
MSLLPPPPPPPPRAPRSSAPHHAQHRAVQRQLASGPVPARGRPPGPGAGQGGHEEVQQPGDQVGELSPSSRMRKLPQGRPVPPLGPETRV
SVVWVERYDDIENFPLSELMTEISTGVETTANSSTSLRSTTLEKEVPVIFIHPLNTGLFRIKIQGATGKFNMVIPLVDGMIVSRRALGFL

--------------------------------------------------------------
>69092_69092_6_PRPS2-RALGAPB_PRPS2_chrX_12817509_ENST00000398491_RALGAPB_chr20_37198531_ENST00000397042_length(transcript)=4646nt_BP=223nt
GCTCCCGCAGCAGCAGCCTCCCGCGTCGCTGTCGCTGTTGCCTCCGCCACCTCCTCCGCCGCCGCGCGCCCCTCGGAGTTCCGCGCCCCA
CCATGCCCAACATCGTGCTGTTCAGCGGCAGCTCGCATCAGGACCTGTCCCAGCGCGTGGCCGACCGCCTGGGCCTGGAGCTGGGCAAGG
TGGTCACGAAGAAGTTCAGCAACCAGGAGACCAGGTAGGAGAGCTCAGTCCCAGTTCCAGAATGAGGAAGCTGCCTCAGGGTCGCCCTGT
TCCTCCCCTTGGACCTGAGACAAGAGTTTCTGTAGTCTGGGTGGAACGCTATGATGATATAGAAAACTTTCCCCTCTCAGAGCTGATGAC
AGAGATCAGTACTGGTGTGGAAACTACTGCAAATAGTAGCACTTCACTGAGATCTACAACTCTTGAAAAAGAAGTTCCTGTCATCTTCAT
CCACCCTTTAAACACTGGATTATTCCGGATAAAAATTCAAGGAGCCACTGGAAAATTTAATATGGTCATCCCTCTTGTGGATGGGATGAT
TGTCAGCAGGCGAGCTCTTGGCTTTCTGGTGAGGCAGACTGTAATTAACATTTGTAGAAGAAAGAGACTGGAAAGTGACTCCTACAGTCC
CCCCCATGTCCGCCGGAAACAGAAAATCACCGACATTGTCAACAAGTACCGGAACAAGCAGCTGGAGCCAGAGTTTTATACTTCACTTTT
CCAGGAGGTTGGACTCAAGAACTGCAGTTCTTAGACCACTGAATTTCTAAGACTGTTGAACTCCAGTTTGGGAACTATAACACAGCAGAA
CAGTTTGATAGGTGATCACTGTAAAAATAAAAACAAATCACTCCCAAGAGCTTACTGTTTAATCACCAGAATAGAAGAAACACATTATAA
CCCATTTGATAGAAGACTTTGGGCTATCTAGTGAAATGGGCTCCCAGACACAATCACACTCCTGCTGATAATGATGATATACATTTTAGC
CATAAACTTTCTTTTAAAAGTGACAATTTTAGTTAAACATAAGCCTTTTGAGGAGAAAGGCTTTTATGCATCTCAGTTAAACACGTGCAT
TGGTAGTATCAACAAATTTGCAATATAGAAGTTGAAGATAGTTTTTTACCTCACTTTTTAGGAGGTTGTATTCAAAATTAAAATCTCAGA
ATCTTACAGGACATTTAAAGACTCATGTTGATAGCATGGAGGAGAAGGAAAGAAGTCACAGCCTTCTACTCAGTTGTAGGTCTTCTTGTC
ATCCAGCTGTCACACTGACAAAAAGAAAAGATGATACATGTTTTTTGCTCAGATAAGAAGCCTGACATTAAAAGATGTCATATTTTTTTC
TCCACATTTCAAAAAGTTGTCCTTCTCATCACTGCACAGATCTGTCTGAAAGCCTCAGTTTCTGAGTGACCCAGGAACAGATCAGAAATG
GAGCATGGCCTTGTCCTTTAATGGGGATGCAAATAAAGTTTGTGGGGTTAAAAGTTATAAGACAGCAGTGATACCCCACTCTCTCCATTA
TTGTCCAGCGGGGTGACATAATGACAGGTTAAATATTTGTGATTCATTGATTAAATATTATTTAAAGAAATGTAAATTCACAATAAGGGT
TGAAAATTATTTGGTTTCATCCATTGTCTCTTATTTCAGGACCAAGCAGCAAACTGCAGTAGTTTGTGAAGGATTCTAATATGGGGTTCA
GGAATAGCCTCTCAACGCTACTAATTCAGATCTCTCCCAGAGAACTACTGGATTTCCTCATAATTGACAAACATGAGTGACCACCTCTTT
GGGTGGCTACTGTTAGAAATGGCTGTTGTCATGTTTTCTGGACTTTGCCAGCCAACAGATCCCTGCCAGGTTTTGGAAATACTTCTATTA
CCTCGCTGCTACTTTTCTGCAGGGATAAAACTTTTGAGGTGGCCAGACCCAGAACATCCAAGGATTCCTGTTACAGTGCTACAGTATACA
CTGCTCATTTATCCTATTCTCATGTGCTTTCTTCTTTAGTAAGATTATTTTAAGAAAATAAGTGATATTTAAAGTCCAAAGAGGAATGAT
CACAGTTGTATAAGGGGTGTTTTCCCACTTGAACTCTGATGTCAGTCGACTGTGGGTCAGAGCTACAACCATCTGTTTGGTTTGATGTTT
TGGTGGTTTACTTACGGAGTGGGGATAGTGTGAGACCTAATTCCCTGTGCAAATGTCTCTTATTCCAGAAATGTGCATTTTGTCATCTAT
AAGCAAGAAATATGGGCATAGCAGCTCTTGGTTTAAAGTTTGCCATAACCTGTTCATGTTTGTTTTAAGCTCAGGTAAAGATAACCTCCT
CTTTCTATGACTCCAGTTTCCATTCAGGTTATAGTATTATTCAATAGTTGATTTTCTTTTTAAGCTGGGCAATAAATTGATGTTTCCAGA
TGGTAACATGGGAGAGGGCATATAGGATAAAGATGAGCAAATTCTACCCTAAAAATGTTCTAGTAGTTCACAGGAAGAAGATGAGGTTTA
ATAACTTTCAAGGTAATTCTAGATTGACATTTTGAGGGGAAAATGGGCTCTTGTTCTAGTTGAAGTGAGCAGAGAAGGCTATAAATTAAT
ATGTAACTTACAGCATTCCAGAGGTTAAAAATAACTGATGCAGATGTACTTCTTCAGTGTGATTCTTCAGATCAAACTTTTACTTTTGGC
ATAGTTAATTTCAGAAAAATGTGCTGTATGTGTGTGTGTATGAGGGTTGGTCTTGCTGATCCTTCAGTTAGCTCTAAATTCTGGCAACTC
CTTGTAATTCCAATGTATTTGATACATGAACAATCATGTTGAATGCATTTGTGATCTGGGAGACTTCCTCGTCTTCCAGGGAAGGAAGGA
TGTGCAGCCCCTGAAGGCATGAAACTCCCAGTGTGTACGGAGCCAGTGGAATATGGGATACCCATACCTTACCAGGCGCTGGTTCCTTCT
GCTCACAATAACATCTGCCCAAAGAGGGAGTGGGAAGAACGCTTAGCTCTTTCACTAGTATGGATTTGAGTTCATGGTCACTATTTTTAC
CCACCTGCCTTTGTTAAAAATCACTTTGAGTAGAATAGCACTGGAGGAACATATTTAGCACCTAATATTAATATTTAGTAGTCCATTGAT
AAATTTGCCAGCATATGTTCTAGCCTCTGGGGGGAAACCAGGACCACTTTTGTCTGTGGCTTAAACAGTTCAGTTGCTATATCTGTTGGG
TATGCCGGGGGTGGATGAGTGTGGCATTCCGTGAAGAGGAAGGTGGTAAGTAAGGTTTCCCTTCTACTGCCTTCTTAAGTTGCAGGAGGG
AGCTTTTCTCCTCCCCTCTGGTTGGGAGCACTGAGGACAGTGAGGAGGGCTTTTACCTTGTTAATCCTTTCCTTATTTAGCTAGCTTTCC
TTTTTGTCTAGGGCTTCCTCTTGAGACCCTCTTCCATCCATTGGGCCTTTGAAAGGACTAATCAGACACACACACACACACACACACACA
CACACACACTCGCATACTCATGCACATTTTCCTTCATTTCCAGATCCTTTATTTCAGAGCAGCCCATTTTCCTCTGGATTCATTGATGAA
TACAAGTACCCACACCTTTGGCCAGTAATGTCAGTTACCTGCTGCAGGTTCTGTGTATGAGGCCTTCATGAACGGTTACCTTCTCCATAC
ACTAGGGAAGCATTTGTCAGACTCTGCAGACTGGGTTCTAGAGAGGCAGAGTCTTTAAGAGTATTCATTTCTTCTGGAAGGTGGAGCTTT
ACCCAAAGTGGAAGTTAGCCTTGCTCAAAGATGTGTTTTGTGGTAGGTGGTAAAAATAAATAAATAAATAAATAATAAAAAAAGAAACAT
GTATTGGAGGTAATTTGACACTGCTGCTGGCAGTAGTTCTCTATTCACCATTTTAAAGCCCATTCAGGTTCTCTCTTCCTGAAAAGAACT
GATTGCTGTGTTTACATGAAATGACATTGGAGTCAGATGGTCTGTTTTAAAGATTTCCATGACAGCCTCTTTTCCTGAGTTGGAGAGATT
GGAGGTGGTCTATCCGTACGATGTGGAATCAAACGGTGGGTTTCTTAGTAGCTAAAGAAGCCATGTACTTCTAGTGTGTTTCTCAGAATA
TCAACTCATGTTCTTCAGATGCTTTTCTTTTTTTAATGGTGAGGGAAAAGGTATAATTTGGGATTCCACAGTGCCTTGCATATAGTAGGC
GCCCAGTAAATACTTGTTGAAGCAAACCAAGTTTCCCAAGTCCTCATCTCTTATAGTGACCAAGACATCTTTCTCCTCTGAAGGGCTTGG
CAGTTGTGGCTAAAAAATAAGCAGTATCATTATTTGCTTGAAATCATATATACAGTTTGTATGAATTTCAGTATGTTGCCAAGACATGAT
TTTTTCTTATTGTATTTTCTGTAAATATTTCTGGCACTGAACTGTAAAGTAAAGGCAAAGTGTAAATATGAAGGCGTGCCCGTGCCCCTT
GCCTCCTGTGTTTCATCTTCGTCGGTTAGGGAAGAAGGTCCAGAGGTTTGTTTGTATTTATGCCGATCCTTTGTCCAGAAGAAGCCCATG

>69092_69092_6_PRPS2-RALGAPB_PRPS2_chrX_12817509_ENST00000398491_RALGAPB_chr20_37198531_ENST00000397042_length(amino acids)=241AA_BP=65
MSLLPPPPPPPPRAPRSSAPHHAQHRAVQRQLASGPVPARGRPPGPGAGQGGHEEVQQPGDQVGELSPSSRMRKLPQGRPVPPLGPETRV
SVVWVERYDDIENFPLSELMTEISTGVETTANSSTSLRSTTLEKEVPVIFIHPLNTGLFRIKIQGATGKFNMVIPLVDGMIVSRRALGFL

--------------------------------------------------------------
>69092_69092_7_PRPS2-RALGAPB_PRPS2_chrX_12817509_ENST00000489404_RALGAPB_chr20_37198531_ENST00000262879_length(transcript)=4739nt_BP=316nt
GCGCCCCACCATGCCCAACATCGTGCTGTTCAGCGGCAGCTCGCATCAGGACCTGTCCCAGCGCGTGGCCGACCGCCTGGGCCTGGAGCT
GGGCAAGGTGGTCACGAAGAAGTTCAGCAACCAGGAGACCAGCGTGGAGATTGGTGAAAGCGTGAGAGGGGAAGATGTCTACATCATCCA
GAGCGGCTGCGGGGAAATTAACGACAACCTGATGGAACTCCTCATCATGATCAATGCCTGCAAGATTGCGTCATCATCCAGAGTAACTGC
CGTGATCCCGTGTTTCCCATACGCCCGACAAGATAAAAAGGACAAGCTCAGTCCCAGTTCCAGAATGAGGAAGCTGCCTCAGGGTCGCCC
TGTTCCTCCCCTTGGACCTGAGACAAGAGTTTCTGTAGTCTGGGTGGAACGCTATGATGATATAGAAAACTTTCCCCTCTCAGAGCTGAT
GACAGAGATCAGTACTGGTGTGGAAACTACTGCAAATAGTAGCACTTCACTGAGATCTACAACTCTTGAAAAAGAAGTTCCTGTCATCTT
CATCCACCCTTTAAACACTGGATTATTCCGGATAAAAATTCAAGGAGCCACTGGAAAATTTAATATGGTCATCCCTCTTGTGGATGGGAT
GATTGTCAGCAGGCGAGCTCTTGGCTTTCTGGTGAGGCAGACTGTAATTAACATTTGTAGAAGAAAGAGACTGGAAAGTGACTCCTACAG
TCCCCCCCATGTCCGCCGGAAACAGAAAATCACCGACATTGTCAACAAGTACCGGAACAAGCAGCTGGAGCCAGAGTTTTATACTTCACT
TTTCCAGGAGGTTGGACTCAAGAACTGCAGTTCTTAGACCACTGAATTTCTAAGACTGTTGAACTCCAGTTTGGGAACTATAACACAGCA
GAACAGTTTGATAGGTGATCACTGTAAAAATAAAAACAAATCACTCCCAAGAGCTTACTGTTTAATCACCAGAATAGAAGAAACACATTA
TAACCCATTTGATAGAAGACTTTGGGCTATCTAGTGAAATGGGCTCCCAGACACAATCACACTCCTGCTGATAATGATGATATACATTTT
AGCCATAAACTTTCTTTTAAAAGTGACAATTTTAGTTAAACATAAGCCTTTTGAGGAGAAAGGCTTTTATGCATCTCAGTTAAACACGTG
CATTGGTAGTATCAACAAATTTGCAATATAGAAGTTGAAGATAGTTTTTTACCTCACTTTTTAGGAGGTTGTATTCAAAATTAAAATCTC
AGAATCTTACAGGACATTTAAAGACTCATGTTGATAGCATGGAGGAGAAGGAAAGAAGTCACAGCCTTCTACTCAGTTGTAGGTCTTCTT
GTCATCCAGCTGTCACACTGACAAAAAGAAAAGATGATACATGTTTTTTGCTCAGATAAGAAGCCTGACATTAAAAGATGTCATATTTTT
TTCTCCACATTTCAAAAAGTTGTCCTTCTCATCACTGCACAGATCTGTCTGAAAGCCTCAGTTTCTGAGTGACCCAGGAACAGATCAGAA
ATGGAGCATGGCCTTGTCCTTTAATGGGGATGCAAATAAAGTTTGTGGGGTTAAAAGTTATAAGACAGCAGTGATACCCCACTCTCTCCA
TTATTGTCCAGCGGGGTGACATAATGACAGGTTAAATATTTGTGATTCATTGATTAAATATTATTTAAAGAAATGTAAATTCACAATAAG
GGTTGAAAATTATTTGGTTTCATCCATTGTCTCTTATTTCAGGACCAAGCAGCAAACTGCAGTAGTTTGTGAAGGATTCTAATATGGGGT
TCAGGAATAGCCTCTCAACGCTACTAATTCAGATCTCTCCCAGAGAACTACTGGATTTCCTCATAATTGACAAACATGAGTGACCACCTC
TTTGGGTGGCTACTGTTAGAAATGGCTGTTGTCATGTTTTCTGGACTTTGCCAGCCAACAGATCCCTGCCAGGTTTTGGAAATACTTCTA
TTACCTCGCTGCTACTTTTCTGCAGGGATAAAACTTTTGAGGTGGCCAGACCCAGAACATCCAAGGATTCCTGTTACAGTGCTACAGTAT
ACACTGCTCATTTATCCTATTCTCATGTGCTTTCTTCTTTAGTAAGATTATTTTAAGAAAATAAGTGATATTTAAAGTCCAAAGAGGAAT
GATCACAGTTGTATAAGGGGTGTTTTCCCACTTGAACTCTGATGTCAGTCGACTGTGGGTCAGAGCTACAACCATCTGTTTGGTTTGATG
TTTTGGTGGTTTACTTACGGAGTGGGGATAGTGTGAGACCTAATTCCCTGTGCAAATGTCTCTTATTCCAGAAATGTGCATTTTGTCATC
TATAAGCAAGAAATATGGGCATAGCAGCTCTTGGTTTAAAGTTTGCCATAACCTGTTCATGTTTGTTTTAAGCTCAGGTAAAGATAACCT
CCTCTTTCTATGACTCCAGTTTCCATTCAGGTTATAGTATTATTCAATAGTTGATTTTCTTTTTAAGCTGGGCAATAAATTGATGTTTCC
AGATGGTAACATGGGAGAGGGCATATAGGATAAAGATGAGCAAATTCTACCCTAAAAATGTTCTAGTAGTTCACAGGAAGAAGATGAGGT
TTAATAACTTTCAAGGTAATTCTAGATTGACATTTTGAGGGGAAAATGGGCTCTTGTTCTAGTTGAAGTGAGCAGAGAAGGCTATAAATT
AATATGTAACTTACAGCATTCCAGAGGTTAAAAATAACTGATGCAGATGTACTTCTTCAGTGTGATTCTTCAGATCAAACTTTTACTTTT
GGCATAGTTAATTTCAGAAAAATGTGCTGTATGTGTGTGTGTATGAGGGTTGGTCTTGCTGATCCTTCAGTTAGCTCTAAATTCTGGCAA
CTCCTTGTAATTCCAATGTATTTGATACATGAACAATCATGTTGAATGCATTTGTGATCTGGGAGACTTCCTCGTCTTCCAGGGAAGGAA
GGATGTGCAGCCCCTGAAGGCATGAAACTCCCAGTGTGTACGGAGCCAGTGGAATATGGGATACCCATACCTTACCAGGCGCTGGTTCCT
TCTGCTCACAATAACATCTGCCCAAAGAGGGAGTGGGAAGAACGCTTAGCTCTTTCACTAGTATGGATTTGAGTTCATGGTCACTATTTT
TACCCACCTGCCTTTGTTAAAAATCACTTTGAGTAGAATAGCACTGGAGGAACATATTTAGCACCTAATATTAATATTTAGTAGTCCATT
GATAAATTTGCCAGCATATGTTCTAGCCTCTGGGGGGAAACCAGGACCACTTTTGTCTGTGGCTTAAACAGTTCAGTTGCTATATCTGTT
GGGTATGCCGGGGGTGGATGAGTGTGGCATTCCGTGAAGAGGAAGGTGGTAAGTAAGGTTTCCCTTCTACTGCCTTCTTAAGTTGCAGGA
GGGAGCTTTTCTCCTCCCCTCTGGTTGGGAGCACTGAGGACAGTGAGGAGGGCTTTTACCTTGTTAATCCTTTCCTTATTTAGCTAGCTT
TCCTTTTTGTCTAGGGCTTCCTCTTGAGACCCTCTTCCATCCATTGGGCCTTTGAAAGGACTAATCAGACACACACACACACACACACAC
ACACACACACACTCGCATACTCATGCACATTTTCCTTCATTTCCAGATCCTTTATTTCAGAGCAGCCCATTTTCCTCTGGATTCATTGAT
GAATACAAGTACCCACACCTTTGGCCAGTAATGTCAGTTACCTGCTGCAGGTTCTGTGTATGAGGCCTTCATGAACGGTTACCTTCTCCA
TACACTAGGGAAGCATTTGTCAGACTCTGCAGACTGGGTTCTAGAGAGGCAGAGTCTTTAAGAGTATTCATTTCTTCTGGAAGGTGGAGC
TTTACCCAAAGTGGAAGTTAGCCTTGCTCAAAGATGTGTTTTGTGGTAGGTGGTAAAAATAAATAAATAAATAAATAATAAAAAAAGAAA
CATGTATTGGAGGTAATTTGACACTGCTGCTGGCAGTAGTTCTCTATTCACCATTTTAAAGCCCATTCAGGTTCTCTCTTCCTGAAAAGA
ACTGATTGCTGTGTTTACATGAAATGACATTGGAGTCAGATGGTCTGTTTTAAAGATTTCCATGACAGCCTCTTTTCCTGAGTTGGAGAG
ATTGGAGGTGGTCTATCCGTACGATGTGGAATCAAACGGTGGGTTTCTTAGTAGCTAAAGAAGCCATGTACTTCTAGTGTGTTTCTCAGA
ATATCAACTCATGTTCTTCAGATGCTTTTCTTTTTTTAATGGTGAGGGAAAAGGTATAATTTGGGATTCCACAGTGCCTTGCATATAGTA
GGCGCCCAGTAAATACTTGTTGAAGCAAACCAAGTTTCCCAAGTCCTCATCTCTTATAGTGACCAAGACATCTTTCTCCTCTGAAGGGCT
TGGCAGTTGTGGCTAAAAAATAAGCAGTATCATTATTTGCTTGAAATCATATATACAGTTTGTATGAATTTCAGTATGTTGCCAAGACAT
GATTTTTTCTTATTGTATTTTCTGTAAATATTTCTGGCACTGAACTGTAAAGTAAAGGCAAAGTGTAAATATGAAGGCGTGCCCGTGCCC
CTTGCCTCCTGTGTTTCATCTTCGTCGGTTAGGGAAGAAGGTCCAGAGGTTTGTTTGTATTTATGCCGATCCTTTGTCCAGAAGAAGCCC

>69092_69092_7_PRPS2-RALGAPB_PRPS2_chrX_12817509_ENST00000489404_RALGAPB_chr20_37198531_ENST00000262879_length(amino acids)=278AA_BP=102
MPNIVLFSGSSHQDLSQRVADRLGLELGKVVTKKFSNQETSVEIGESVRGEDVYIIQSGCGEINDNLMELLIMINACKIASSSRVTAVIP
CFPYARQDKKDKLSPSSRMRKLPQGRPVPPLGPETRVSVVWVERYDDIENFPLSELMTEISTGVETTANSSTSLRSTTLEKEVPVIFIHP
LNTGLFRIKIQGATGKFNMVIPLVDGMIVSRRALGFLVRQTVINICRRKRLESDSYSPPHVRRKQKITDIVNKYRNKQLEPEFYTSLFQE

--------------------------------------------------------------
>69092_69092_8_PRPS2-RALGAPB_PRPS2_chrX_12817509_ENST00000489404_RALGAPB_chr20_37198531_ENST00000397038_length(transcript)=4741nt_BP=316nt
GCGCCCCACCATGCCCAACATCGTGCTGTTCAGCGGCAGCTCGCATCAGGACCTGTCCCAGCGCGTGGCCGACCGCCTGGGCCTGGAGCT
GGGCAAGGTGGTCACGAAGAAGTTCAGCAACCAGGAGACCAGCGTGGAGATTGGTGAAAGCGTGAGAGGGGAAGATGTCTACATCATCCA
GAGCGGCTGCGGGGAAATTAACGACAACCTGATGGAACTCCTCATCATGATCAATGCCTGCAAGATTGCGTCATCATCCAGAGTAACTGC
CGTGATCCCGTGTTTCCCATACGCCCGACAAGATAAAAAGGACAAGCTCAGTCCCAGTTCCAGAATGAGGAAGCTGCCTCAGGGTCGCCC
TGTTCCTCCCCTTGGACCTGAGACAAGAGTTTCTGTAGTCTGGGTGGAACGCTATGATGATATAGAAAACTTTCCCCTCTCAGAGCTGAT
GACAGAGATCAGTACTGGTGTGGAAACTACTGCAAATAGTAGCACTTCACTGAGATCTACAACTCTTGAAAAAGAAGTTCCTGTCATCTT
CATCCACCCTTTAAACACTGGATTATTCCGGATAAAAATTCAAGGAGCCACTGGAAAATTTAATATGGTCATCCCTCTTGTGGATGGGAT
GATTGTCAGCAGGCGAGCTCTTGGCTTTCTGGTGAGGCAGACTGTAATTAACATTTGTAGAAGAAAGAGACTGGAAAGTGACTCCTACAG
TCCCCCCCATGTCCGCCGGAAACAGAAAATCACCGACATTGTCAACAAGTACCGGAACAAGCAGCTGGAGCCAGAGTTTTATACTTCACT
TTTCCAGGAGGTTGGACTCAAGAACTGCAGTTCTTAGACCACTGAATTTCTAAGACTGTTGAACTCCAGTTTGGGAACTATAACACAGCA
GAACAGTTTGATAGGTGATCACTGTAAAAATAAAAACAAATCACTCCCAAGAGCTTACTGTTTAATCACCAGAATAGAAGAAACACATTA
TAACCCATTTGATAGAAGACTTTGGGCTATCTAGTGAAATGGGCTCCCAGACACAATCACACTCCTGCTGATAATGATGATATACATTTT
AGCCATAAACTTTCTTTTAAAAGTGACAATTTTAGTTAAACATAAGCCTTTTGAGGAGAAAGGCTTTTATGCATCTCAGTTAAACACGTG
CATTGGTAGTATCAACAAATTTGCAATATAGAAGTTGAAGATAGTTTTTTACCTCACTTTTTAGGAGGTTGTATTCAAAATTAAAATCTC
AGAATCTTACAGGACATTTAAAGACTCATGTTGATAGCATGGAGGAGAAGGAAAGAAGTCACAGCCTTCTACTCAGTTGTAGGTCTTCTT
GTCATCCAGCTGTCACACTGACAAAAAGAAAAGATGATACATGTTTTTTGCTCAGATAAGAAGCCTGACATTAAAAGATGTCATATTTTT
TTCTCCACATTTCAAAAAGTTGTCCTTCTCATCACTGCACAGATCTGTCTGAAAGCCTCAGTTTCTGAGTGACCCAGGAACAGATCAGAA
ATGGAGCATGGCCTTGTCCTTTAATGGGGATGCAAATAAAGTTTGTGGGGTTAAAAGTTATAAGACAGCAGTGATACCCCACTCTCTCCA
TTATTGTCCAGCGGGGTGACATAATGACAGGTTAAATATTTGTGATTCATTGATTAAATATTATTTAAAGAAATGTAAATTCACAATAAG
GGTTGAAAATTATTTGGTTTCATCCATTGTCTCTTATTTCAGGACCAAGCAGCAAACTGCAGTAGTTTGTGAAGGATTCTAATATGGGGT
TCAGGAATAGCCTCTCAACGCTACTAATTCAGATCTCTCCCAGAGAACTACTGGATTTCCTCATAATTGACAAACATGAGTGACCACCTC
TTTGGGTGGCTACTGTTAGAAATGGCTGTTGTCATGTTTTCTGGACTTTGCCAGCCAACAGATCCCTGCCAGGTTTTGGAAATACTTCTA
TTACCTCGCTGCTACTTTTCTGCAGGGATAAAACTTTTGAGGTGGCCAGACCCAGAACATCCAAGGATTCCTGTTACAGTGCTACAGTAT
ACACTGCTCATTTATCCTATTCTCATGTGCTTTCTTCTTTAGTAAGATTATTTTAAGAAAATAAGTGATATTTAAAGTCCAAAGAGGAAT
GATCACAGTTGTATAAGGGGTGTTTTCCCACTTGAACTCTGATGTCAGTCGACTGTGGGTCAGAGCTACAACCATCTGTTTGGTTTGATG
TTTTGGTGGTTTACTTACGGAGTGGGGATAGTGTGAGACCTAATTCCCTGTGCAAATGTCTCTTATTCCAGAAATGTGCATTTTGTCATC
TATAAGCAAGAAATATGGGCATAGCAGCTCTTGGTTTAAAGTTTGCCATAACCTGTTCATGTTTGTTTTAAGCTCAGGTAAAGATAACCT
CCTCTTTCTATGACTCCAGTTTCCATTCAGGTTATAGTATTATTCAATAGTTGATTTTCTTTTTAAGCTGGGCAATAAATTGATGTTTCC
AGATGGTAACATGGGAGAGGGCATATAGGATAAAGATGAGCAAATTCTACCCTAAAAATGTTCTAGTAGTTCACAGGAAGAAGATGAGGT
TTAATAACTTTCAAGGTAATTCTAGATTGACATTTTGAGGGGAAAATGGGCTCTTGTTCTAGTTGAAGTGAGCAGAGAAGGCTATAAATT
AATATGTAACTTACAGCATTCCAGAGGTTAAAAATAACTGATGCAGATGTACTTCTTCAGTGTGATTCTTCAGATCAAACTTTTACTTTT
GGCATAGTTAATTTCAGAAAAATGTGCTGTATGTGTGTGTGTATGAGGGTTGGTCTTGCTGATCCTTCAGTTAGCTCTAAATTCTGGCAA
CTCCTTGTAATTCCAATGTATTTGATACATGAACAATCATGTTGAATGCATTTGTGATCTGGGAGACTTCCTCGTCTTCCAGGGAAGGAA
GGATGTGCAGCCCCTGAAGGCATGAAACTCCCAGTGTGTACGGAGCCAGTGGAATATGGGATACCCATACCTTACCAGGCGCTGGTTCCT
TCTGCTCACAATAACATCTGCCCAAAGAGGGAGTGGGAAGAACGCTTAGCTCTTTCACTAGTATGGATTTGAGTTCATGGTCACTATTTT
TACCCACCTGCCTTTGTTAAAAATCACTTTGAGTAGAATAGCACTGGAGGAACATATTTAGCACCTAATATTAATATTTAGTAGTCCATT
GATAAATTTGCCAGCATATGTTCTAGCCTCTGGGGGGAAACCAGGACCACTTTTGTCTGTGGCTTAAACAGTTCAGTTGCTATATCTGTT
GGGTATGCCGGGGGTGGATGAGTGTGGCATTCCGTGAAGAGGAAGGTGGTAAGTAAGGTTTCCCTTCTACTGCCTTCTTAAGTTGCAGGA
GGGAGCTTTTCTCCTCCCCTCTGGTTGGGAGCACTGAGGACAGTGAGGAGGGCTTTTACCTTGTTAATCCTTTCCTTATTTAGCTAGCTT
TCCTTTTTGTCTAGGGCTTCCTCTTGAGACCCTCTTCCATCCATTGGGCCTTTGAAAGGACTAATCAGACACACACACACACACACACAC
ACACACACACACTCGCATACTCATGCACATTTTCCTTCATTTCCAGATCCTTTATTTCAGAGCAGCCCATTTTCCTCTGGATTCATTGAT
GAATACAAGTACCCACACCTTTGGCCAGTAATGTCAGTTACCTGCTGCAGGTTCTGTGTATGAGGCCTTCATGAACGGTTACCTTCTCCA
TACACTAGGGAAGCATTTGTCAGACTCTGCAGACTGGGTTCTAGAGAGGCAGAGTCTTTAAGAGTATTCATTTCTTCTGGAAGGTGGAGC
TTTACCCAAAGTGGAAGTTAGCCTTGCTCAAAGATGTGTTTTGTGGTAGGTGGTAAAAATAAATAAATAAATAAATAATAAAAAAAGAAA
CATGTATTGGAGGTAATTTGACACTGCTGCTGGCAGTAGTTCTCTATTCACCATTTTAAAGCCCATTCAGGTTCTCTCTTCCTGAAAAGA
ACTGATTGCTGTGTTTACATGAAATGACATTGGAGTCAGATGGTCTGTTTTAAAGATTTCCATGACAGCCTCTTTTCCTGAGTTGGAGAG
ATTGGAGGTGGTCTATCCGTACGATGTGGAATCAAACGGTGGGTTTCTTAGTAGCTAAAGAAGCCATGTACTTCTAGTGTGTTTCTCAGA
ATATCAACTCATGTTCTTCAGATGCTTTTCTTTTTTTAATGGTGAGGGAAAAGGTATAATTTGGGATTCCACAGTGCCTTGCATATAGTA
GGCGCCCAGTAAATACTTGTTGAAGCAAACCAAGTTTCCCAAGTCCTCATCTCTTATAGTGACCAAGACATCTTTCTCCTCTGAAGGGCT
TGGCAGTTGTGGCTAAAAAATAAGCAGTATCATTATTTGCTTGAAATCATATATACAGTTTGTATGAATTTCAGTATGTTGCCAAGACAT
GATTTTTTCTTATTGTATTTTCTGTAAATATTTCTGGCACTGAACTGTAAAGTAAAGGCAAAGTGTAAATATGAAGGCGTGCCCGTGCCC
CTTGCCTCCTGTGTTTCATCTTCGTCGGTTAGGGAAGAAGGTCCAGAGGTTTGTTTGTATTTATGCCGATCCTTTGTCCAGAAGAAGCCC

>69092_69092_8_PRPS2-RALGAPB_PRPS2_chrX_12817509_ENST00000489404_RALGAPB_chr20_37198531_ENST00000397038_length(amino acids)=278AA_BP=102
MPNIVLFSGSSHQDLSQRVADRLGLELGKVVTKKFSNQETSVEIGESVRGEDVYIIQSGCGEINDNLMELLIMINACKIASSSRVTAVIP
CFPYARQDKKDKLSPSSRMRKLPQGRPVPPLGPETRVSVVWVERYDDIENFPLSELMTEISTGVETTANSSTSLRSTTLEKEVPVIFIHP
LNTGLFRIKIQGATGKFNMVIPLVDGMIVSRRALGFLVRQTVINICRRKRLESDSYSPPHVRRKQKITDIVNKYRNKQLEPEFYTSLFQE

--------------------------------------------------------------
>69092_69092_9_PRPS2-RALGAPB_PRPS2_chrX_12817509_ENST00000489404_RALGAPB_chr20_37198531_ENST00000397042_length(transcript)=4739nt_BP=316nt
GCGCCCCACCATGCCCAACATCGTGCTGTTCAGCGGCAGCTCGCATCAGGACCTGTCCCAGCGCGTGGCCGACCGCCTGGGCCTGGAGCT
GGGCAAGGTGGTCACGAAGAAGTTCAGCAACCAGGAGACCAGCGTGGAGATTGGTGAAAGCGTGAGAGGGGAAGATGTCTACATCATCCA
GAGCGGCTGCGGGGAAATTAACGACAACCTGATGGAACTCCTCATCATGATCAATGCCTGCAAGATTGCGTCATCATCCAGAGTAACTGC
CGTGATCCCGTGTTTCCCATACGCCCGACAAGATAAAAAGGACAAGCTCAGTCCCAGTTCCAGAATGAGGAAGCTGCCTCAGGGTCGCCC
TGTTCCTCCCCTTGGACCTGAGACAAGAGTTTCTGTAGTCTGGGTGGAACGCTATGATGATATAGAAAACTTTCCCCTCTCAGAGCTGAT
GACAGAGATCAGTACTGGTGTGGAAACTACTGCAAATAGTAGCACTTCACTGAGATCTACAACTCTTGAAAAAGAAGTTCCTGTCATCTT
CATCCACCCTTTAAACACTGGATTATTCCGGATAAAAATTCAAGGAGCCACTGGAAAATTTAATATGGTCATCCCTCTTGTGGATGGGAT
GATTGTCAGCAGGCGAGCTCTTGGCTTTCTGGTGAGGCAGACTGTAATTAACATTTGTAGAAGAAAGAGACTGGAAAGTGACTCCTACAG
TCCCCCCCATGTCCGCCGGAAACAGAAAATCACCGACATTGTCAACAAGTACCGGAACAAGCAGCTGGAGCCAGAGTTTTATACTTCACT
TTTCCAGGAGGTTGGACTCAAGAACTGCAGTTCTTAGACCACTGAATTTCTAAGACTGTTGAACTCCAGTTTGGGAACTATAACACAGCA
GAACAGTTTGATAGGTGATCACTGTAAAAATAAAAACAAATCACTCCCAAGAGCTTACTGTTTAATCACCAGAATAGAAGAAACACATTA
TAACCCATTTGATAGAAGACTTTGGGCTATCTAGTGAAATGGGCTCCCAGACACAATCACACTCCTGCTGATAATGATGATATACATTTT
AGCCATAAACTTTCTTTTAAAAGTGACAATTTTAGTTAAACATAAGCCTTTTGAGGAGAAAGGCTTTTATGCATCTCAGTTAAACACGTG
CATTGGTAGTATCAACAAATTTGCAATATAGAAGTTGAAGATAGTTTTTTACCTCACTTTTTAGGAGGTTGTATTCAAAATTAAAATCTC
AGAATCTTACAGGACATTTAAAGACTCATGTTGATAGCATGGAGGAGAAGGAAAGAAGTCACAGCCTTCTACTCAGTTGTAGGTCTTCTT
GTCATCCAGCTGTCACACTGACAAAAAGAAAAGATGATACATGTTTTTTGCTCAGATAAGAAGCCTGACATTAAAAGATGTCATATTTTT
TTCTCCACATTTCAAAAAGTTGTCCTTCTCATCACTGCACAGATCTGTCTGAAAGCCTCAGTTTCTGAGTGACCCAGGAACAGATCAGAA
ATGGAGCATGGCCTTGTCCTTTAATGGGGATGCAAATAAAGTTTGTGGGGTTAAAAGTTATAAGACAGCAGTGATACCCCACTCTCTCCA
TTATTGTCCAGCGGGGTGACATAATGACAGGTTAAATATTTGTGATTCATTGATTAAATATTATTTAAAGAAATGTAAATTCACAATAAG
GGTTGAAAATTATTTGGTTTCATCCATTGTCTCTTATTTCAGGACCAAGCAGCAAACTGCAGTAGTTTGTGAAGGATTCTAATATGGGGT
TCAGGAATAGCCTCTCAACGCTACTAATTCAGATCTCTCCCAGAGAACTACTGGATTTCCTCATAATTGACAAACATGAGTGACCACCTC
TTTGGGTGGCTACTGTTAGAAATGGCTGTTGTCATGTTTTCTGGACTTTGCCAGCCAACAGATCCCTGCCAGGTTTTGGAAATACTTCTA
TTACCTCGCTGCTACTTTTCTGCAGGGATAAAACTTTTGAGGTGGCCAGACCCAGAACATCCAAGGATTCCTGTTACAGTGCTACAGTAT
ACACTGCTCATTTATCCTATTCTCATGTGCTTTCTTCTTTAGTAAGATTATTTTAAGAAAATAAGTGATATTTAAAGTCCAAAGAGGAAT
GATCACAGTTGTATAAGGGGTGTTTTCCCACTTGAACTCTGATGTCAGTCGACTGTGGGTCAGAGCTACAACCATCTGTTTGGTTTGATG
TTTTGGTGGTTTACTTACGGAGTGGGGATAGTGTGAGACCTAATTCCCTGTGCAAATGTCTCTTATTCCAGAAATGTGCATTTTGTCATC
TATAAGCAAGAAATATGGGCATAGCAGCTCTTGGTTTAAAGTTTGCCATAACCTGTTCATGTTTGTTTTAAGCTCAGGTAAAGATAACCT
CCTCTTTCTATGACTCCAGTTTCCATTCAGGTTATAGTATTATTCAATAGTTGATTTTCTTTTTAAGCTGGGCAATAAATTGATGTTTCC
AGATGGTAACATGGGAGAGGGCATATAGGATAAAGATGAGCAAATTCTACCCTAAAAATGTTCTAGTAGTTCACAGGAAGAAGATGAGGT
TTAATAACTTTCAAGGTAATTCTAGATTGACATTTTGAGGGGAAAATGGGCTCTTGTTCTAGTTGAAGTGAGCAGAGAAGGCTATAAATT
AATATGTAACTTACAGCATTCCAGAGGTTAAAAATAACTGATGCAGATGTACTTCTTCAGTGTGATTCTTCAGATCAAACTTTTACTTTT
GGCATAGTTAATTTCAGAAAAATGTGCTGTATGTGTGTGTGTATGAGGGTTGGTCTTGCTGATCCTTCAGTTAGCTCTAAATTCTGGCAA
CTCCTTGTAATTCCAATGTATTTGATACATGAACAATCATGTTGAATGCATTTGTGATCTGGGAGACTTCCTCGTCTTCCAGGGAAGGAA
GGATGTGCAGCCCCTGAAGGCATGAAACTCCCAGTGTGTACGGAGCCAGTGGAATATGGGATACCCATACCTTACCAGGCGCTGGTTCCT
TCTGCTCACAATAACATCTGCCCAAAGAGGGAGTGGGAAGAACGCTTAGCTCTTTCACTAGTATGGATTTGAGTTCATGGTCACTATTTT
TACCCACCTGCCTTTGTTAAAAATCACTTTGAGTAGAATAGCACTGGAGGAACATATTTAGCACCTAATATTAATATTTAGTAGTCCATT
GATAAATTTGCCAGCATATGTTCTAGCCTCTGGGGGGAAACCAGGACCACTTTTGTCTGTGGCTTAAACAGTTCAGTTGCTATATCTGTT
GGGTATGCCGGGGGTGGATGAGTGTGGCATTCCGTGAAGAGGAAGGTGGTAAGTAAGGTTTCCCTTCTACTGCCTTCTTAAGTTGCAGGA
GGGAGCTTTTCTCCTCCCCTCTGGTTGGGAGCACTGAGGACAGTGAGGAGGGCTTTTACCTTGTTAATCCTTTCCTTATTTAGCTAGCTT
TCCTTTTTGTCTAGGGCTTCCTCTTGAGACCCTCTTCCATCCATTGGGCCTTTGAAAGGACTAATCAGACACACACACACACACACACAC
ACACACACACACTCGCATACTCATGCACATTTTCCTTCATTTCCAGATCCTTTATTTCAGAGCAGCCCATTTTCCTCTGGATTCATTGAT
GAATACAAGTACCCACACCTTTGGCCAGTAATGTCAGTTACCTGCTGCAGGTTCTGTGTATGAGGCCTTCATGAACGGTTACCTTCTCCA
TACACTAGGGAAGCATTTGTCAGACTCTGCAGACTGGGTTCTAGAGAGGCAGAGTCTTTAAGAGTATTCATTTCTTCTGGAAGGTGGAGC
TTTACCCAAAGTGGAAGTTAGCCTTGCTCAAAGATGTGTTTTGTGGTAGGTGGTAAAAATAAATAAATAAATAAATAATAAAAAAAGAAA
CATGTATTGGAGGTAATTTGACACTGCTGCTGGCAGTAGTTCTCTATTCACCATTTTAAAGCCCATTCAGGTTCTCTCTTCCTGAAAAGA
ACTGATTGCTGTGTTTACATGAAATGACATTGGAGTCAGATGGTCTGTTTTAAAGATTTCCATGACAGCCTCTTTTCCTGAGTTGGAGAG
ATTGGAGGTGGTCTATCCGTACGATGTGGAATCAAACGGTGGGTTTCTTAGTAGCTAAAGAAGCCATGTACTTCTAGTGTGTTTCTCAGA
ATATCAACTCATGTTCTTCAGATGCTTTTCTTTTTTTAATGGTGAGGGAAAAGGTATAATTTGGGATTCCACAGTGCCTTGCATATAGTA
GGCGCCCAGTAAATACTTGTTGAAGCAAACCAAGTTTCCCAAGTCCTCATCTCTTATAGTGACCAAGACATCTTTCTCCTCTGAAGGGCT
TGGCAGTTGTGGCTAAAAAATAAGCAGTATCATTATTTGCTTGAAATCATATATACAGTTTGTATGAATTTCAGTATGTTGCCAAGACAT
GATTTTTTCTTATTGTATTTTCTGTAAATATTTCTGGCACTGAACTGTAAAGTAAAGGCAAAGTGTAAATATGAAGGCGTGCCCGTGCCC
CTTGCCTCCTGTGTTTCATCTTCGTCGGTTAGGGAAGAAGGTCCAGAGGTTTGTTTGTATTTATGCCGATCCTTTGTCCAGAAGAAGCCC

>69092_69092_9_PRPS2-RALGAPB_PRPS2_chrX_12817509_ENST00000489404_RALGAPB_chr20_37198531_ENST00000397042_length(amino acids)=278AA_BP=102
MPNIVLFSGSSHQDLSQRVADRLGLELGKVVTKKFSNQETSVEIGESVRGEDVYIIQSGCGEINDNLMELLIMINACKIASSSRVTAVIP
CFPYARQDKKDKLSPSSRMRKLPQGRPVPPLGPETRVSVVWVERYDDIENFPLSELMTEISTGVETTANSSTSLRSTTLEKEVPVIFIHP
LNTGLFRIKIQGATGKFNMVIPLVDGMIVSRRALGFLVRQTVINICRRKRLESDSYSPPHVRRKQKITDIVNKYRNKQLEPEFYTSLFQE

--------------------------------------------------------------

Top

Fusion Gene PPI Analysis for PRPS2-RALGAPB


check button Go to ChiPPI (Chimeric Protein-Protein interactions) to see the chimeric PPI interaction in

ChiPPI page.


check button Protein-protein interactors with each fusion partner protein in wild-type (BIOGRID-3.4.160)
HgeneHgene's interactorsTgeneTgene's interactors


check button - Retained PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenStill interaction with


check button - Lost PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


check button - Retained PPIs, but lost function due to frame-shift fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


Top

Related Drugs for PRPS2-RALGAPB


check button Drugs targeting genes involved in this fusion gene.
(DrugBank Version 5.1.8 2021-05-08)
PartnerGeneUniProtAccDrugBank IDDrug nameDrug activityDrug typeDrug status

Top

Related Diseases for PRPS2-RALGAPB


check button Diseases associated with fusion partners.
(DisGeNet 4.0)
PartnerGeneDisease IDDisease name# pubmedsSource