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	Fusion Gene Summary
	Fusion Gene ORF analysis
	Fusion Genomic Features
	Fusion Protein Features
	Fusion Gene Sequence
	Fusion Gene PPI analysis
	Related Drugs
	Related Diseases

Fusion gene:PSAT1-WAC (FusionGDB2 ID:69433)

Fusion Gene Summary for PSAT1-WAC

Fusion gene summary

Fusion gene information	Fusion gene name: PSAT1-WAC
	Fusion gene ID: 69433
		Hgene	Tgene
	Gene symbol	PSAT1	WAC
	Gene ID	29968	51322
	Gene name	phosphoserine aminotransferase 1	WW domain containing adaptor with coiled-coil
	Synonyms	EPIP\|NLS2\|PSA\|PSAT\|PSATD	BM-016\|DESSH\|PRO1741\|Wwp4
	Cytomap	9q21.2	10p12.1\|10p12.1-p11.2
	Type of gene	protein-coding	protein-coding
	Description	phosphoserine aminotransferaseendometrial progesterone-induced proteinphosphohydroxythreonine aminotransferase	WW domain-containing adapter protein with coiled-coil
	Modification date	20200313	20200313
	UniProtAcc	.	.
	Ensembl transtripts involved in fusion gene	ENST00000347159, ENST00000376588,	ENST00000428935, ENST00000532233, ENST00000347934, ENST00000354911, ENST00000375646, ENST00000375664,
Fusion gene scores	* DoF score	8 X 7 X 5=280	13 X 16 X 7=1456
	# samples	9	16
	** MAII score	log2(9/280*10)=-1.63742992061529 possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs). DoF>8 and MAII<0	log2(16/1456*10)=-3.18586654531133 possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs). DoF>8 and MAII<0
Context	PubMed: PSAT1 [Title/Abstract] AND WAC [Title/Abstract] AND fusion [Title/Abstract]
Most frequent breakpoint	PSAT1(80923499)-WAC(28905101), # samples:1
Anticipated loss of major functional domain due to fusion event.

* DoF score (Degree of Frequency) = # partners X # break points X # cancer types
** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10)

Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez

Partner

Gene

GO ID

GO term

PubMed ID

Fusion gene breakpoints across PSAT1 (5'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.

Fusion gene breakpoints across WAC (3'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.

Fusion gene information from two resources (ChiTars 5.0 and ChimerDB 4.0)
* All genome coordinats were lifted-over on hg19.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.

Source	Disease	Sample	Hgene	Hchr	Hbp	Hstrand	Tgene	Tchr	Tbp	Tstrand
ChimerDB4	ESCA	TCGA-LN-A4A2	PSAT1	chr9	80923499	+	WAC	chr10	28905101	+

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Fusion Gene ORF analysis for PSAT1-WAC

Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.

ORF	Henst	Tenst	Hgene	Hchr	Hbp	Hstrand	Tgene	Tchr	Tbp	Tstrand
5CDS-intron	ENST00000347159	ENST00000428935	PSAT1	chr9	80923499	+	WAC	chr10	28905101	+
5CDS-intron	ENST00000347159	ENST00000532233	PSAT1	chr9	80923499	+	WAC	chr10	28905101	+
5CDS-intron	ENST00000376588	ENST00000428935	PSAT1	chr9	80923499	+	WAC	chr10	28905101	+
5CDS-intron	ENST00000376588	ENST00000532233	PSAT1	chr9	80923499	+	WAC	chr10	28905101	+
In-frame	ENST00000347159	ENST00000347934	PSAT1	chr9	80923499	+	WAC	chr10	28905101	+
In-frame	ENST00000347159	ENST00000354911	PSAT1	chr9	80923499	+	WAC	chr10	28905101	+
In-frame	ENST00000347159	ENST00000375646	PSAT1	chr9	80923499	+	WAC	chr10	28905101	+
In-frame	ENST00000347159	ENST00000375664	PSAT1	chr9	80923499	+	WAC	chr10	28905101	+
In-frame	ENST00000376588	ENST00000347934	PSAT1	chr9	80923499	+	WAC	chr10	28905101	+
In-frame	ENST00000376588	ENST00000354911	PSAT1	chr9	80923499	+	WAC	chr10	28905101	+
In-frame	ENST00000376588	ENST00000375646	PSAT1	chr9	80923499	+	WAC	chr10	28905101	+
In-frame	ENST00000376588	ENST00000375664	PSAT1	chr9	80923499	+	WAC	chr10	28905101	+

ORFfinder result based on the fusion transcript sequence of in-frame fusion genes.

Henst	Tenst	Hgene	Hchr	Hbp	Hstrand	Tgene	Tchr	Tbp	Tstrand	Seq length (transcript)	BP loci (transcript)	Predicted start (transcript)	Predicted stop (transcript)	Seq length (amino acids)
ENST00000347159	PSAT1	chr9	80923499	+	ENST00000375664	WAC	chr10	28905101	+	4702	808	41	1195	384
ENST00000347159	PSAT1	chr9	80923499	+	ENST00000375646	WAC	chr10	28905101	+	1566	808	41	1195	384
ENST00000347159	PSAT1	chr9	80923499	+	ENST00000347934	WAC	chr10	28905101	+	2133	808	41	1195	384
ENST00000347159	PSAT1	chr9	80923499	+	ENST00000354911	WAC	chr10	28905101	+	2133	808	41	1195	384
ENST00000376588	PSAT1	chr9	80923499	+	ENST00000375664	WAC	chr10	28905101	+	4702	808	41	1195	384
ENST00000376588	PSAT1	chr9	80923499	+	ENST00000375646	WAC	chr10	28905101	+	1566	808	41	1195	384
ENST00000376588	PSAT1	chr9	80923499	+	ENST00000347934	WAC	chr10	28905101	+	2133	808	41	1195	384
ENST00000376588	PSAT1	chr9	80923499	+	ENST00000354911	WAC	chr10	28905101	+	2133	808	41	1195	384

DeepORF prediction of the coding potential based on the fusion transcript sequence of in-frame fusion genes. DeepORF is a coding potential classifier based on convolutional neural network by comparing the real Ribo-seq data. If the no-coding score < 0.5 and coding score > 0.5, then the in-frame fusion transcript is predicted as being likely translated.

Henst	Tenst	Hgene	Hchr	Hbp	Hstrand	Tgene	Tchr	Tbp	Tstrand	No-coding score	Coding score
ENST00000347159	ENST00000375664	PSAT1	chr9	80923499	+	WAC	chr10	28905101	+	0.000181004	0.999819
ENST00000347159	ENST00000375646	PSAT1	chr9	80923499	+	WAC	chr10	28905101	+	0.000708253	0.9992918
ENST00000347159	ENST00000347934	PSAT1	chr9	80923499	+	WAC	chr10	28905101	+	0.000518163	0.99948186
ENST00000347159	ENST00000354911	PSAT1	chr9	80923499	+	WAC	chr10	28905101	+	0.000518163	0.99948186
ENST00000376588	ENST00000375664	PSAT1	chr9	80923499	+	WAC	chr10	28905101	+	0.000181004	0.999819
ENST00000376588	ENST00000375646	PSAT1	chr9	80923499	+	WAC	chr10	28905101	+	0.000708253	0.9992918
ENST00000376588	ENST00000347934	PSAT1	chr9	80923499	+	WAC	chr10	28905101	+	0.000518163	0.99948186
ENST00000376588	ENST00000354911	PSAT1	chr9	80923499	+	WAC	chr10	28905101	+	0.000518163	0.99948186

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Fusion Genomic Features for PSAT1-WAC

FusionAI prediction of the potential fusion gene breakpoint based on the pre-mature RNA sequence context (+/- 5kb of individual partner genes, total 20kb length sequence). FusionAI is a fusion gene breakpoint classifier based on convolutional neural network by comparing the fusion positive and negative sequence context of ~ 20K fusion gene data. From here, we can have the relative potentency of the 20K genomic sequence how individual sequnce will be likely used as the gene fusion breakpoints.

Hgene	Hchr	Hbp	Hstrand	Tgene	Tchr	Tbp	Tstrand	1-p	p (fusion gene breakpoint)
PSAT1	chr9	80923499	+	WAC	chr10	28905101	+	0.002165702	0.99783427
PSAT1	chr9	80923499	+	WAC	chr10	28905101	+	0.002165702	0.99783427

Distribution of 44 human genomic features loci across 20kb length fusion breakpoint regions. We integrated a total of 44 different types of human genomic feature loci information across five big categories including virus integration sites, repeats, structural variants, chromatin states, and gene expression regulation. More details are in help page.

Distribution of 44 human genomic features loci across 20kb length fusion breakpoint regions that are ovelapped with the top 1% feature importance score regions. More details are in help page.

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Fusion Protein Features for PSAT1-WAC

Four levels of functional features of fusion genes
Go to FGviewer search page for the most frequent breakpoint (https://ccsmweb.uth.edu/FGviewer/chr9:80923499/chr10:28905101)
- FGviewer provides the online visualization of the retention search of the protein functional features across DNA, RNA, protein, and pathological levels.
- How to search
1. Put your fusion gene symbol.
2. Press the tab key until there will be shown the breakpoint information filled.
4. Go down and press 'Search' tab twice.
4. Go down to have the hyperlink of the search result.
5. Click the hyperlink.
6. See the FGviewer result for your fusion gene.

Main function of each fusion partner protein. (from UniProt)

Hgene	Tgene
.	.
FUNCTION: Transcriptional activator which is required for calcium-dependent dendritic growth and branching in cortical neurons. Recruits CREB-binding protein (CREBBP) to nuclear bodies. Component of the CREST-BRG1 complex, a multiprotein complex that regulates promoter activation by orchestrating a calcium-dependent release of a repressor complex and a recruitment of an activator complex. In resting neurons, transcription of the c-FOS promoter is inhibited by BRG1-dependent recruitment of a phospho-RB1-HDAC1 repressor complex. Upon calcium influx, RB1 is dephosphorylated by calcineurin, which leads to release of the repressor complex. At the same time, there is increased recruitment of CREBBP to the promoter by a CREST-dependent mechanism, which leads to transcriptional activation. The CREST-BRG1 complex also binds to the NR2B promoter, and activity-dependent induction of NR2B expression involves a release of HDAC1 and recruitment of CREBBP (By similarity). {ECO:0000250}.	FUNCTION: Transcriptional activator which is required for calcium-dependent dendritic growth and branching in cortical neurons. Recruits CREB-binding protein (CREBBP) to nuclear bodies. Component of the CREST-BRG1 complex, a multiprotein complex that regulates promoter activation by orchestrating a calcium-dependent release of a repressor complex and a recruitment of an activator complex. In resting neurons, transcription of the c-FOS promoter is inhibited by BRG1-dependent recruitment of a phospho-RB1-HDAC1 repressor complex. Upon calcium influx, RB1 is dephosphorylated by calcineurin, which leads to release of the repressor complex. At the same time, there is increased recruitment of CREBBP to the promoter by a CREST-dependent mechanism, which leads to transcriptional activation. The CREST-BRG1 complex also binds to the NR2B promoter, and activity-dependent induction of NR2B expression involves a release of HDAC1 and recruitment of CREBBP (By similarity). {ECO:0000250}.

Retention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at
download page

* Minus value of BPloci means that the break pointn is located before the CDS.

- In-frame and retained protein feature among the 13 regional features.

Partner

Gene

Hbp

Tbp

ENST

Strand

BPexon

TotalExon

Protein feature loci

*BPloci

TotalLen

Protein feature

Protein feature note

Hgene

PSAT1

chr9:80923499

chr10:28905101

ENST00000347159

241_242

246

325.0

Region

Pyridoxal phosphate binding

Hgene

PSAT1

chr9:80923499

chr10:28905101

ENST00000347159

79_80

246

325.0

Region

Pyridoxal phosphate binding

Hgene

PSAT1

chr9:80923499

chr10:28905101

ENST00000376588

241_242

246

371.0

Region

Pyridoxal phosphate binding

Hgene

PSAT1

chr9:80923499

chr10:28905101

ENST00000376588

79_80

246

371.0

Region

Pyridoxal phosphate binding

Tgene

WAC

chr9:80923499

chr10:28905101

ENST00000347934

618_644

415

545.0

Coiled coil

Ontology_term=ECO:0000255

Tgene

WAC

chr9:80923499

chr10:28905101

ENST00000354911

618_644

518

648.0

Coiled coil

Ontology_term=ECO:0000255

Tgene

WAC

chr9:80923499

chr10:28905101

ENST00000375664

618_644

473

603.0

Coiled coil

Ontology_term=ECO:0000255

Tgene

WAC

chr9:80923499

chr10:28905101

ENST00000428935

618_644

437.0

Coiled coil

Ontology_term=ECO:0000255

Tgene

WAC

chr9:80923499

chr10:28905101

ENST00000428935

129_162

437.0

Domain

- In-frame and not-retained protein feature among the 13 regional features.

Partner

Gene

Hbp

Tbp

ENST

Strand

BPexon

TotalExon

Protein feature loci

*BPloci

TotalLen

Protein feature

Protein feature note

Tgene

WAC

chr9:80923499

chr10:28905101

ENST00000347934

129_162

415

545.0

Domain

Tgene

WAC

chr9:80923499

chr10:28905101

ENST00000354911

129_162

518

648.0

Domain

Tgene

WAC

chr9:80923499

chr10:28905101

ENST00000375664

129_162

473

603.0

Domain

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Fusion Gene Sequence for PSAT1-WAC

For in-frame fusion transcripts, we provide the fusion transcript sequences and fusion amino acid sequences. To have fusion amino acid sequence, we ran ORFfinder and chose the longest ORF among the all predicted ones.

>69433_69433_1_PSAT1-WAC_PSAT1_chr9_80923499_ENST00000347159_WAC_chr10_28905101_ENST00000347934_length(transcript)=2133nt_BP=808nt
GGCCAGGAACGCCAGCCGTTCACGCGTTCGGTCCTCCTTGGCTGACTCACCGCCCTGGCCGCCGCACCATGGACGCCCCCAGGCAGGTGG
TCAACTTTGGGCCTGGTCCCGCCAAGCTGCCGCACTCAGTGTTGTTAGAGATACAAAAGGAATTATTAGACTACAAAGGAGTTGGCATTA
GTGTTCTTGAAATGAGTCACAGGTCATCAGATTTTGCCAAGATTATTAACAATACAGAGAATCTTGTGCGGGAATTGCTAGCTGTTCCAG
ACAACTATAAGGTGATTTTTCTGCAAGGAGGTGGGTGCGGCCAGTTCAGTGCTGTCCCCTTAAACCTCATTGGCTTGAAAGCAGGAAGGT
GTGCTGACTATGTGGTGACAGGAGCTTGGTCAGCTAAGGCCGCAGAAGAAGCCAAGAAGTTTGGGACTATAAATATCGTTCACCCTAAAC
TTGGGAGTTATACAAAAATTCCAGATCCAAGCACCTGGAACCTCAACCCAGATGCCTCCTACGTGTATTATTGCGCAAATGAGACGGTGC
ATGGTGTGGAGTTTGACTTTATACCCGATGTCAAGGGAGCAGTACTGGTTTGTGACATGTCCTCAAACTTCCTGTCCAAGCCAGTGGATG
TTTCCAAGTTTGGTGTGATTTTTGCTGGTGCCCAGAAGAATGTTGGCTCTGCTGGGGTCACCGTGGTGATTGTCCGTGATGACCTGCTGG
GGTTTGCCCTCCGAGAGTGCCCCTCGGTCCTGGAATACAAGGTGCAGGCTGGAAACAGCTCCTTGTACAACACGCCTCCATGTTTCAGTA
GCCAGAGAAGTCCATCACCTGGTCCCAATCATACTTCTAATAGTAGTAATGCATCAAATGCAACAGTTGTACCACAGAATTCTTCTGCCC
GATCCACGTGTTCATTAACGCCTGCACTAGCAGCACACTTCAGTGAAAATCTCATAAAACACGTTCAAGGATGGCCTGCAGATCATGCAG
AGAAGCAGGCATCAAGATTACGCGAAGAAGCGCATAACATGGGAACTATTCACATGTCCGAAATTTGTACTGAATTAAAAAATTTAAGAT
CTTTAGTCCGAGTATGTGAAATTCAAGCAACTTTGCGAGAGCAAAGGATACTATTTTTGAGACAACAAATTAAGGAACTTGAAAAGCTAA
AAAATCAGAATTCCTTCATGGTGTGAAGATGTGAATAATTGCACATGGTTTTGAGAACAGGAACTGTAAATCTGTTGCCCAATCTTAACA
TTTTTGAGCTGCATTTAAGTAGACTTTGGACCGTTAAGCTGGGCAAAGGAAATGACAAGGGGACGGGGTCTGTGAGAGTCAATTCAGGGG
AAAGATACAAGATTGATTTGTAAAACCCTTGAAATGTAGATTTCTTGTAGATGTATCCTTCACGTTGTAAATATGTTTTGTAGAGTGAAG
CCATGGGAAGCCATGTGTAACAGAGCTTAGACATCCAAAACTAATCAATGCTGAGGTGGCTAAATACCTAGCCTTTTACATGTAAACCTG
TCTGCAAAATTAGCTTTTTTAAAAAAAAAAAAAAAAAAATTGGGGGGGTTAATTTATCATTCAGAAATCTTGCATTTTCAAAAATTCAGT
GCAAGCGCCAGGCGATTTGTGTCTAAGGATACGATTTTGAACCATATGGGCAGTGTACAAAATATGAAACAACTGTTTCCACACTTGCAC
CTGATCAAGAGCAGTGCTTCTCCATTTGTTTTGCAGAGAAATGTTTTTCATTTCCCGTGTGTTTCCATTTCCTTCTGAAATTCTGATTTT
ATCCATTTTTTTAAGGCTCCTCTTTATCTCCTTTCTTAAGGCACTGTTGCTATGGCACTTTTCTATAACCTTTTCATTCCTGTGTACAGT
AGCTTAAAATTGCAGTGATTGAGCATAACCTACTTGTTTGTATAAATTATTGAAATCCATTTGCACCCTGTTAAGAATGGACTTAAAAGT
ACTGCTGGACAGGCATGTGTGCTCAAAGTACATTGATTGCTCAAATATAAGGAAATGGCCCAATGAACGTGGTTGTGGGAGGGGAAAGAG

>69433_69433_1_PSAT1-WAC_PSAT1_chr9_80923499_ENST00000347159_WAC_chr10_28905101_ENST00000347934_length(amino acids)=384AA_BP=255
MTHRPGRRTMDAPRQVVNFGPGPAKLPHSVLLEIQKELLDYKGVGISVLEMSHRSSDFAKIINNTENLVRELLAVPDNYKVIFLQGGGCG
QFSAVPLNLIGLKAGRCADYVVTGAWSAKAAEEAKKFGTINIVHPKLGSYTKIPDPSTWNLNPDASYVYYCANETVHGVEFDFIPDVKGA
VLVCDMSSNFLSKPVDVSKFGVIFAGAQKNVGSAGVTVVIVRDDLLGFALRECPSVLEYKVQAGNSSLYNTPPCFSSQRSPSPGPNHTSN
SSNASNATVVPQNSSARSTCSLTPALAAHFSENLIKHVQGWPADHAEKQASRLREEAHNMGTIHMSEICTELKNLRSLVRVCEIQATLRE

--------------------------------------------------------------
>69433_69433_2_PSAT1-WAC_PSAT1_chr9_80923499_ENST00000347159_WAC_chr10_28905101_ENST00000354911_length(transcript)=2133nt_BP=808nt
GGCCAGGAACGCCAGCCGTTCACGCGTTCGGTCCTCCTTGGCTGACTCACCGCCCTGGCCGCCGCACCATGGACGCCCCCAGGCAGGTGG
TCAACTTTGGGCCTGGTCCCGCCAAGCTGCCGCACTCAGTGTTGTTAGAGATACAAAAGGAATTATTAGACTACAAAGGAGTTGGCATTA
GTGTTCTTGAAATGAGTCACAGGTCATCAGATTTTGCCAAGATTATTAACAATACAGAGAATCTTGTGCGGGAATTGCTAGCTGTTCCAG
ACAACTATAAGGTGATTTTTCTGCAAGGAGGTGGGTGCGGCCAGTTCAGTGCTGTCCCCTTAAACCTCATTGGCTTGAAAGCAGGAAGGT
GTGCTGACTATGTGGTGACAGGAGCTTGGTCAGCTAAGGCCGCAGAAGAAGCCAAGAAGTTTGGGACTATAAATATCGTTCACCCTAAAC
TTGGGAGTTATACAAAAATTCCAGATCCAAGCACCTGGAACCTCAACCCAGATGCCTCCTACGTGTATTATTGCGCAAATGAGACGGTGC
ATGGTGTGGAGTTTGACTTTATACCCGATGTCAAGGGAGCAGTACTGGTTTGTGACATGTCCTCAAACTTCCTGTCCAAGCCAGTGGATG
TTTCCAAGTTTGGTGTGATTTTTGCTGGTGCCCAGAAGAATGTTGGCTCTGCTGGGGTCACCGTGGTGATTGTCCGTGATGACCTGCTGG
GGTTTGCCCTCCGAGAGTGCCCCTCGGTCCTGGAATACAAGGTGCAGGCTGGAAACAGCTCCTTGTACAACACGCCTCCATGTTTCAGTA
GCCAGAGAAGTCCATCACCTGGTCCCAATCATACTTCTAATAGTAGTAATGCATCAAATGCAACAGTTGTACCACAGAATTCTTCTGCCC
GATCCACGTGTTCATTAACGCCTGCACTAGCAGCACACTTCAGTGAAAATCTCATAAAACACGTTCAAGGATGGCCTGCAGATCATGCAG
AGAAGCAGGCATCAAGATTACGCGAAGAAGCGCATAACATGGGAACTATTCACATGTCCGAAATTTGTACTGAATTAAAAAATTTAAGAT
CTTTAGTCCGAGTATGTGAAATTCAAGCAACTTTGCGAGAGCAAAGGATACTATTTTTGAGACAACAAATTAAGGAACTTGAAAAGCTAA
AAAATCAGAATTCCTTCATGGTGTGAAGATGTGAATAATTGCACATGGTTTTGAGAACAGGAACTGTAAATCTGTTGCCCAATCTTAACA
TTTTTGAGCTGCATTTAAGTAGACTTTGGACCGTTAAGCTGGGCAAAGGAAATGACAAGGGGACGGGGTCTGTGAGAGTCAATTCAGGGG
AAAGATACAAGATTGATTTGTAAAACCCTTGAAATGTAGATTTCTTGTAGATGTATCCTTCACGTTGTAAATATGTTTTGTAGAGTGAAG
CCATGGGAAGCCATGTGTAACAGAGCTTAGACATCCAAAACTAATCAATGCTGAGGTGGCTAAATACCTAGCCTTTTACATGTAAACCTG
TCTGCAAAATTAGCTTTTTTAAAAAAAAAAAAAAAAAAATTGGGGGGGTTAATTTATCATTCAGAAATCTTGCATTTTCAAAAATTCAGT
GCAAGCGCCAGGCGATTTGTGTCTAAGGATACGATTTTGAACCATATGGGCAGTGTACAAAATATGAAACAACTGTTTCCACACTTGCAC
CTGATCAAGAGCAGTGCTTCTCCATTTGTTTTGCAGAGAAATGTTTTTCATTTCCCGTGTGTTTCCATTTCCTTCTGAAATTCTGATTTT
ATCCATTTTTTTAAGGCTCCTCTTTATCTCCTTTCTTAAGGCACTGTTGCTATGGCACTTTTCTATAACCTTTTCATTCCTGTGTACAGT
AGCTTAAAATTGCAGTGATTGAGCATAACCTACTTGTTTGTATAAATTATTGAAATCCATTTGCACCCTGTTAAGAATGGACTTAAAAGT
ACTGCTGGACAGGCATGTGTGCTCAAAGTACATTGATTGCTCAAATATAAGGAAATGGCCCAATGAACGTGGTTGTGGGAGGGGAAAGAG

>69433_69433_2_PSAT1-WAC_PSAT1_chr9_80923499_ENST00000347159_WAC_chr10_28905101_ENST00000354911_length(amino acids)=384AA_BP=255
MTHRPGRRTMDAPRQVVNFGPGPAKLPHSVLLEIQKELLDYKGVGISVLEMSHRSSDFAKIINNTENLVRELLAVPDNYKVIFLQGGGCG
QFSAVPLNLIGLKAGRCADYVVTGAWSAKAAEEAKKFGTINIVHPKLGSYTKIPDPSTWNLNPDASYVYYCANETVHGVEFDFIPDVKGA
VLVCDMSSNFLSKPVDVSKFGVIFAGAQKNVGSAGVTVVIVRDDLLGFALRECPSVLEYKVQAGNSSLYNTPPCFSSQRSPSPGPNHTSN
SSNASNATVVPQNSSARSTCSLTPALAAHFSENLIKHVQGWPADHAEKQASRLREEAHNMGTIHMSEICTELKNLRSLVRVCEIQATLRE

--------------------------------------------------------------
>69433_69433_3_PSAT1-WAC_PSAT1_chr9_80923499_ENST00000347159_WAC_chr10_28905101_ENST00000375646_length(transcript)=1566nt_BP=808nt
GGCCAGGAACGCCAGCCGTTCACGCGTTCGGTCCTCCTTGGCTGACTCACCGCCCTGGCCGCCGCACCATGGACGCCCCCAGGCAGGTGG
TCAACTTTGGGCCTGGTCCCGCCAAGCTGCCGCACTCAGTGTTGTTAGAGATACAAAAGGAATTATTAGACTACAAAGGAGTTGGCATTA
GTGTTCTTGAAATGAGTCACAGGTCATCAGATTTTGCCAAGATTATTAACAATACAGAGAATCTTGTGCGGGAATTGCTAGCTGTTCCAG
ACAACTATAAGGTGATTTTTCTGCAAGGAGGTGGGTGCGGCCAGTTCAGTGCTGTCCCCTTAAACCTCATTGGCTTGAAAGCAGGAAGGT
GTGCTGACTATGTGGTGACAGGAGCTTGGTCAGCTAAGGCCGCAGAAGAAGCCAAGAAGTTTGGGACTATAAATATCGTTCACCCTAAAC
TTGGGAGTTATACAAAAATTCCAGATCCAAGCACCTGGAACCTCAACCCAGATGCCTCCTACGTGTATTATTGCGCAAATGAGACGGTGC
ATGGTGTGGAGTTTGACTTTATACCCGATGTCAAGGGAGCAGTACTGGTTTGTGACATGTCCTCAAACTTCCTGTCCAAGCCAGTGGATG
TTTCCAAGTTTGGTGTGATTTTTGCTGGTGCCCAGAAGAATGTTGGCTCTGCTGGGGTCACCGTGGTGATTGTCCGTGATGACCTGCTGG
GGTTTGCCCTCCGAGAGTGCCCCTCGGTCCTGGAATACAAGGTGCAGGCTGGAAACAGCTCCTTGTACAACACGCCTCCATGTTTCAGTA
GCCAGAGAAGTCCATCACCTGGTCCCAATCATACTTCTAATAGTAGTAATGCATCAAATGCAACAGTTGTACCACAGAATTCTTCTGCCC
GATCCACGTGTTCATTAACGCCTGCACTAGCAGCACACTTCAGTGAAAATCTCATAAAACACGTTCAAGGATGGCCTGCAGATCATGCAG
AGAAGCAGGCATCAAGATTACGCGAAGAAGCGCATAACATGGGAACTATTCACATGTCCGAAATTTGTACTGAATTAAAAAATTTAAGAT
CTTTAGTCCGAGTATGTGAAATTCAAGCAACTTTGCGAGAGCAAAGGATACTATTTTTGAGACAACAAATTAAGGAACTTGAAAAGCTAA
AAAATCAGAATTCCTTCATGGTGTGAAGATGTGAATAATTGCACATGGTTTTGAGAACAGGAACTGTAAATCTGTTGCCCAATCTTAACA
TTTTTGAGCTGCATTTAAGTAGACTTTGGACCGTTAAGCTGGGCAAAGGAAATGACAAGGGGACGGGGTCTGTGAGAGTCAATTCAGGGG
AAAGATACAAGATTGATTTGTAAAACCCTTGAAATGTAGATTTCTTGTAGATGTATCCTTCACGTTGTAAATATGTTTTGTAGAGTGAAG
CCATGGGAAGCCATGTGTAACAGAGCTTAGACATCCAAAACTAATCAATGCTGAGGTGGCTAAATACCTAGCCTTTTACATGTAAACCTG

>69433_69433_3_PSAT1-WAC_PSAT1_chr9_80923499_ENST00000347159_WAC_chr10_28905101_ENST00000375646_length(amino acids)=384AA_BP=255
MTHRPGRRTMDAPRQVVNFGPGPAKLPHSVLLEIQKELLDYKGVGISVLEMSHRSSDFAKIINNTENLVRELLAVPDNYKVIFLQGGGCG
QFSAVPLNLIGLKAGRCADYVVTGAWSAKAAEEAKKFGTINIVHPKLGSYTKIPDPSTWNLNPDASYVYYCANETVHGVEFDFIPDVKGA
VLVCDMSSNFLSKPVDVSKFGVIFAGAQKNVGSAGVTVVIVRDDLLGFALRECPSVLEYKVQAGNSSLYNTPPCFSSQRSPSPGPNHTSN
SSNASNATVVPQNSSARSTCSLTPALAAHFSENLIKHVQGWPADHAEKQASRLREEAHNMGTIHMSEICTELKNLRSLVRVCEIQATLRE

--------------------------------------------------------------
>69433_69433_4_PSAT1-WAC_PSAT1_chr9_80923499_ENST00000347159_WAC_chr10_28905101_ENST00000375664_length(transcript)=4702nt_BP=808nt
GGCCAGGAACGCCAGCCGTTCACGCGTTCGGTCCTCCTTGGCTGACTCACCGCCCTGGCCGCCGCACCATGGACGCCCCCAGGCAGGTGG
TCAACTTTGGGCCTGGTCCCGCCAAGCTGCCGCACTCAGTGTTGTTAGAGATACAAAAGGAATTATTAGACTACAAAGGAGTTGGCATTA
GTGTTCTTGAAATGAGTCACAGGTCATCAGATTTTGCCAAGATTATTAACAATACAGAGAATCTTGTGCGGGAATTGCTAGCTGTTCCAG
ACAACTATAAGGTGATTTTTCTGCAAGGAGGTGGGTGCGGCCAGTTCAGTGCTGTCCCCTTAAACCTCATTGGCTTGAAAGCAGGAAGGT
GTGCTGACTATGTGGTGACAGGAGCTTGGTCAGCTAAGGCCGCAGAAGAAGCCAAGAAGTTTGGGACTATAAATATCGTTCACCCTAAAC
TTGGGAGTTATACAAAAATTCCAGATCCAAGCACCTGGAACCTCAACCCAGATGCCTCCTACGTGTATTATTGCGCAAATGAGACGGTGC
ATGGTGTGGAGTTTGACTTTATACCCGATGTCAAGGGAGCAGTACTGGTTTGTGACATGTCCTCAAACTTCCTGTCCAAGCCAGTGGATG
TTTCCAAGTTTGGTGTGATTTTTGCTGGTGCCCAGAAGAATGTTGGCTCTGCTGGGGTCACCGTGGTGATTGTCCGTGATGACCTGCTGG
GGTTTGCCCTCCGAGAGTGCCCCTCGGTCCTGGAATACAAGGTGCAGGCTGGAAACAGCTCCTTGTACAACACGCCTCCATGTTTCAGTA
GCCAGAGAAGTCCATCACCTGGTCCCAATCATACTTCTAATAGTAGTAATGCATCAAATGCAACAGTTGTACCACAGAATTCTTCTGCCC
GATCCACGTGTTCATTAACGCCTGCACTAGCAGCACACTTCAGTGAAAATCTCATAAAACACGTTCAAGGATGGCCTGCAGATCATGCAG
AGAAGCAGGCATCAAGATTACGCGAAGAAGCGCATAACATGGGAACTATTCACATGTCCGAAATTTGTACTGAATTAAAAAATTTAAGAT
CTTTAGTCCGAGTATGTGAAATTCAAGCAACTTTGCGAGAGCAAAGGATACTATTTTTGAGACAACAAATTAAGGAACTTGAAAAGCTAA
AAAATCAGAATTCCTTCATGGTGTGAAGATGTGAATAATTGCACATGGTTTTGAGAACAGGAACTGTAAATCTGTTGCCCAATCTTAACA
TTTTTGAGCTGCATTTAAGTAGACTTTGGACCGTTAAGCTGGGCAAAGGAAATGACAAGGGGACGGGGTCTGTGAGAGTCAATTCAGGGG
AAAGATACAAGATTGATTTGTAAAACCCTTGAAATGTAGATTTCTTGTAGATGTATCCTTCACGTTGTAAATATGTTTTGTAGAGTGAAG
CCATGGGAAGCCATGTGTAACAGAGCTTAGACATCCAAAACTAATCAATGCTGAGGTGGCTAAATACCTAGCCTTTTACATGTAAACCTG
TCTGCAAAATTAGCTTTTTTAAAAAAAAAAAAAAAAAAATTGGGGGGGTTAATTTATCATTCAGAAATCTTGCATTTTCAAAAATTCAGT
GCAAGCGCCAGGCGATTTGTGTCTAAGGATACGATTTTGAACCATATGGGCAGTGTACAAAATATGAAACAACTGTTTCCACACTTGCAC
CTGATCAAGAGCAGTGCTTCTCCATTTGTTTTGCAGAGAAATGTTTTTCATTTCCCGTGTGTTTCCATTTCCTTCTGAAATTCTGATTTT
ATCCATTTTTTTAAGGCTCCTCTTTATCTCCTTTCTTAAGGCACTGTTGCTATGGCACTTTTCTATAACCTTTTCATTCCTGTGTACAGT
AGCTTAAAATTGCAGTGATTGAGCATAACCTACTTGTTTGTATAAATTATTGAAATCCATTTGCACCCTGTTAAGAATGGACTTAAAAGT
ACTGCTGGACAGGCATGTGTGCTCAAAGTACATTGATTGCTCAAATATAAGGAAATGGCCCAATGAACGTGGTTGTGGGAGGGGAAAGAG
GAAACAGAGCTAGTCAGATGTGAATTGTATCTGTTGTAATAAACATGTTAAAACAAACAAAAATTGTTATTTTTCTTTTCCTTCGGTCAG
TGCACATTAGCATTTGAACTACCTGGGGATTCTTTATCAGAACTGTTCTTGTTGAATATTTATACTTAATTGAAATAATTCCTTAAGGGA
GGTTTTGTTTAAAACGTATTAACAGGAAATTGTGTATGAGATATTTAATGAAATAAGAAATTCAACAAGAATGATTAAGTCACTTCCCAA
GTGGTTGTCATTTGTTAAACCCTGGTTTACCTGTCTTGCTATTATGACATTTCATTTGGAAGGATGTTTGTGTTGTAGCTAACTGTTCAA
GTCTGGTGCTGACTGCTGTTCTTAGCCATCACAAAACGCTAAATTTGTGTAATTGGAGCTTCCTGCTGTTATCTGGAAATAGCAGGAAAG
CGCAGCTTTGTATATTGTTTCCTAAAGTATATTAAAATAAAAAAAGAAACTATTGCTACTATAAAATTACCTTGACTTTTTTTTTCCTTT
GCTGAAATATTAGTCACATAGCCTTAGCTTCACACTGCCAGTAATGTATCAAATCACAAGGGTTTCCGCATGAAAAAAATCTTTTCTTCC
CCCACAAAAAAACCTTTACCATCAAAATCTTGCCATCTGATTTAGAAAGGTGTTTCTTCTTCTTCTTCTTTTTTTTCTTTAAATTGGTTT
AGGGTTTTTTGGTGATTTTTTTTTTTTTTTTTTTTCTGTTGGGGCAGATAAGTGCTTCCAAAACTGGCAGCACCAAGGGCTTATTTTTTA
TGTTAGACATCAATGTCAATGTTACTACATTCTCGGATGCTAACATAAATTTTGAAATTGCTCTTGTGCTTTAAGCATATATTGAAAGTA
TGGAAGTTAAATGTTCAGGCTTTTCAGTAAGCTCAAAAAGTTAACTGTAAGCGATAGTGTTGGTGTTTTCTAAAATACAAAAATGTTCCA
GTGTAATTAAAAGGAATTAAAATCTTGAAGATATTTTCCTGTAATTTAAGGATACTTTTTAAATGTAAGAAAAGACATGTCATTAATTTA
TTGTCATGTTTATACCTCTGTGAGATTGTTAACATCTGCTGAATTTAACTAGTGCATGTAAATGAAACCCCAAAGAGCTGTGTGTTCAGC
TAGAAACCTTACTGTATCTTTCCTGGAAAGAAGTGAGCAATTTGTTGTAATAGGCAAATGTTTCCTGATCAGATGGCAATTTGTGATTTA
GGTAAATTTGAATTTGATTTGCTTATAGTCTACTGGTCTGTGTACCTATGTTTTGTTTTTCAAAAAAGTTTACATCCCTAAATGAATTAG
TCACATATATTTAGGAGAAGATGCCTAATTTGGTATTTCTTAATAGTGAATTTTTTTTTTTCTTGAGACAGAGTTTCACTCTTGTTGCCC
AGGCTGGAGTGCAATGGCACGATCTCGGCTCACCGCAACCTCTGCCTCCTGGGTTCAAGCGATTCTCCTGCCTCGGCGTTCCGAGTAGCT
GGGATTACAGGCATGCACCACCACGCCTGGCTAATTTTGTATTTTTAGTAGAGATGGGGTTTCTCCATGTTGGTCAGGCTGGTCTTGAAC
TGCCAACTTCAGGTGATCTGCCTGCCTTGGCCTCCCAAAGTGCTGGGATTACAGGCGTGAGCCACCGCTCCTGGCCAGTAGTGAATTTTT
AAACACAGAAAATCTAAAATTTTGTGGAAATATTTTAAATATTGCACCTTAATACAAGGTATCCAGCTCCTAACCTTAACTAGGGAATAT
CTATTAAAATAAGCATAATGTTCTGGACTAGAGTATTCCTTATCTAGTTGGTTATGGATTTGAACATGTACCTTGGTTTAGATACTTTGA
AAATAGAAGTACTGAATAGCCTCTAGGGAACTTGAGTGGCCTTTCCCTCCCCCTGCCCCCCCCCCCCCCCCCCCGTTTTAAAAGATCAGT
AGTCTCTATTCAAACTTTTAAAATGTCGTGGTATTGTAACAATATATTTGATGAAAGAAGGTTACAGACTCCCCTGAAGAACCAGCTTTC
CTACGCTTTTTATTTTTCTAACTTGTCTAACCTGATTTTAAAATGACTGCAATTCCAGACTAAAAACATGCTTCAGCCCTGTTTCAAGAC
ATTATGCTTCTTTTAACAGTCCAAATTAGTAGTTTTATTTTTCTTCTAAATCTTTGTTTCACACTTGTAAAATCTTGGGAAGGAGGTTCT
TAAAACTTTGCCAGGAATTGTTACCCATTTCCAAAAACAGTTTATTATGTTCAAAAACCACCATATCTTTGAGGGACTGTTTGAAAGGGG
AGAGGGCAACGCGGGAAATAATTCACTCTGCGCACCGGAACTATTGTAGTTCAGGACTTCCAGCTACTGTATTTAGATGTTGGGTTTGAA
TATACAGATTTCTTTTCAATACCTGTAAATATGGCTATATTCTTGTATTTGTACGGGAGTGTACAAAATGACACTGAAAAGTAATAAATA
TGTTTTGACTATATTGTGCAGTTATTTCAGAACTGTGTTTTGAAAGTCTTAGAATGCATAATTTGCATTTGAGTAAGGAAATTTAAAATA

>69433_69433_4_PSAT1-WAC_PSAT1_chr9_80923499_ENST00000347159_WAC_chr10_28905101_ENST00000375664_length(amino acids)=384AA_BP=255
MTHRPGRRTMDAPRQVVNFGPGPAKLPHSVLLEIQKELLDYKGVGISVLEMSHRSSDFAKIINNTENLVRELLAVPDNYKVIFLQGGGCG
QFSAVPLNLIGLKAGRCADYVVTGAWSAKAAEEAKKFGTINIVHPKLGSYTKIPDPSTWNLNPDASYVYYCANETVHGVEFDFIPDVKGA
VLVCDMSSNFLSKPVDVSKFGVIFAGAQKNVGSAGVTVVIVRDDLLGFALRECPSVLEYKVQAGNSSLYNTPPCFSSQRSPSPGPNHTSN
SSNASNATVVPQNSSARSTCSLTPALAAHFSENLIKHVQGWPADHAEKQASRLREEAHNMGTIHMSEICTELKNLRSLVRVCEIQATLRE

--------------------------------------------------------------
>69433_69433_5_PSAT1-WAC_PSAT1_chr9_80923499_ENST00000376588_WAC_chr10_28905101_ENST00000347934_length(transcript)=2133nt_BP=808nt
GGCCAGGAACGCCAGCCGTTCACGCGTTCGGTCCTCCTTGGCTGACTCACCGCCCTGGCCGCCGCACCATGGACGCCCCCAGGCAGGTGG
TCAACTTTGGGCCTGGTCCCGCCAAGCTGCCGCACTCAGTGTTGTTAGAGATACAAAAGGAATTATTAGACTACAAAGGAGTTGGCATTA
GTGTTCTTGAAATGAGTCACAGGTCATCAGATTTTGCCAAGATTATTAACAATACAGAGAATCTTGTGCGGGAATTGCTAGCTGTTCCAG
ACAACTATAAGGTGATTTTTCTGCAAGGAGGTGGGTGCGGCCAGTTCAGTGCTGTCCCCTTAAACCTCATTGGCTTGAAAGCAGGAAGGT
GTGCTGACTATGTGGTGACAGGAGCTTGGTCAGCTAAGGCCGCAGAAGAAGCCAAGAAGTTTGGGACTATAAATATCGTTCACCCTAAAC
TTGGGAGTTATACAAAAATTCCAGATCCAAGCACCTGGAACCTCAACCCAGATGCCTCCTACGTGTATTATTGCGCAAATGAGACGGTGC
ATGGTGTGGAGTTTGACTTTATACCCGATGTCAAGGGAGCAGTACTGGTTTGTGACATGTCCTCAAACTTCCTGTCCAAGCCAGTGGATG
TTTCCAAGTTTGGTGTGATTTTTGCTGGTGCCCAGAAGAATGTTGGCTCTGCTGGGGTCACCGTGGTGATTGTCCGTGATGACCTGCTGG
GGTTTGCCCTCCGAGAGTGCCCCTCGGTCCTGGAATACAAGGTGCAGGCTGGAAACAGCTCCTTGTACAACACGCCTCCATGTTTCAGTA
GCCAGAGAAGTCCATCACCTGGTCCCAATCATACTTCTAATAGTAGTAATGCATCAAATGCAACAGTTGTACCACAGAATTCTTCTGCCC
GATCCACGTGTTCATTAACGCCTGCACTAGCAGCACACTTCAGTGAAAATCTCATAAAACACGTTCAAGGATGGCCTGCAGATCATGCAG
AGAAGCAGGCATCAAGATTACGCGAAGAAGCGCATAACATGGGAACTATTCACATGTCCGAAATTTGTACTGAATTAAAAAATTTAAGAT
CTTTAGTCCGAGTATGTGAAATTCAAGCAACTTTGCGAGAGCAAAGGATACTATTTTTGAGACAACAAATTAAGGAACTTGAAAAGCTAA
AAAATCAGAATTCCTTCATGGTGTGAAGATGTGAATAATTGCACATGGTTTTGAGAACAGGAACTGTAAATCTGTTGCCCAATCTTAACA
TTTTTGAGCTGCATTTAAGTAGACTTTGGACCGTTAAGCTGGGCAAAGGAAATGACAAGGGGACGGGGTCTGTGAGAGTCAATTCAGGGG
AAAGATACAAGATTGATTTGTAAAACCCTTGAAATGTAGATTTCTTGTAGATGTATCCTTCACGTTGTAAATATGTTTTGTAGAGTGAAG
CCATGGGAAGCCATGTGTAACAGAGCTTAGACATCCAAAACTAATCAATGCTGAGGTGGCTAAATACCTAGCCTTTTACATGTAAACCTG
TCTGCAAAATTAGCTTTTTTAAAAAAAAAAAAAAAAAAATTGGGGGGGTTAATTTATCATTCAGAAATCTTGCATTTTCAAAAATTCAGT
GCAAGCGCCAGGCGATTTGTGTCTAAGGATACGATTTTGAACCATATGGGCAGTGTACAAAATATGAAACAACTGTTTCCACACTTGCAC
CTGATCAAGAGCAGTGCTTCTCCATTTGTTTTGCAGAGAAATGTTTTTCATTTCCCGTGTGTTTCCATTTCCTTCTGAAATTCTGATTTT
ATCCATTTTTTTAAGGCTCCTCTTTATCTCCTTTCTTAAGGCACTGTTGCTATGGCACTTTTCTATAACCTTTTCATTCCTGTGTACAGT
AGCTTAAAATTGCAGTGATTGAGCATAACCTACTTGTTTGTATAAATTATTGAAATCCATTTGCACCCTGTTAAGAATGGACTTAAAAGT
ACTGCTGGACAGGCATGTGTGCTCAAAGTACATTGATTGCTCAAATATAAGGAAATGGCCCAATGAACGTGGTTGTGGGAGGGGAAAGAG

>69433_69433_5_PSAT1-WAC_PSAT1_chr9_80923499_ENST00000376588_WAC_chr10_28905101_ENST00000347934_length(amino acids)=384AA_BP=255
MTHRPGRRTMDAPRQVVNFGPGPAKLPHSVLLEIQKELLDYKGVGISVLEMSHRSSDFAKIINNTENLVRELLAVPDNYKVIFLQGGGCG
QFSAVPLNLIGLKAGRCADYVVTGAWSAKAAEEAKKFGTINIVHPKLGSYTKIPDPSTWNLNPDASYVYYCANETVHGVEFDFIPDVKGA
VLVCDMSSNFLSKPVDVSKFGVIFAGAQKNVGSAGVTVVIVRDDLLGFALRECPSVLEYKVQAGNSSLYNTPPCFSSQRSPSPGPNHTSN
SSNASNATVVPQNSSARSTCSLTPALAAHFSENLIKHVQGWPADHAEKQASRLREEAHNMGTIHMSEICTELKNLRSLVRVCEIQATLRE

--------------------------------------------------------------
>69433_69433_6_PSAT1-WAC_PSAT1_chr9_80923499_ENST00000376588_WAC_chr10_28905101_ENST00000354911_length(transcript)=2133nt_BP=808nt
GGCCAGGAACGCCAGCCGTTCACGCGTTCGGTCCTCCTTGGCTGACTCACCGCCCTGGCCGCCGCACCATGGACGCCCCCAGGCAGGTGG
TCAACTTTGGGCCTGGTCCCGCCAAGCTGCCGCACTCAGTGTTGTTAGAGATACAAAAGGAATTATTAGACTACAAAGGAGTTGGCATTA
GTGTTCTTGAAATGAGTCACAGGTCATCAGATTTTGCCAAGATTATTAACAATACAGAGAATCTTGTGCGGGAATTGCTAGCTGTTCCAG
ACAACTATAAGGTGATTTTTCTGCAAGGAGGTGGGTGCGGCCAGTTCAGTGCTGTCCCCTTAAACCTCATTGGCTTGAAAGCAGGAAGGT
GTGCTGACTATGTGGTGACAGGAGCTTGGTCAGCTAAGGCCGCAGAAGAAGCCAAGAAGTTTGGGACTATAAATATCGTTCACCCTAAAC
TTGGGAGTTATACAAAAATTCCAGATCCAAGCACCTGGAACCTCAACCCAGATGCCTCCTACGTGTATTATTGCGCAAATGAGACGGTGC
ATGGTGTGGAGTTTGACTTTATACCCGATGTCAAGGGAGCAGTACTGGTTTGTGACATGTCCTCAAACTTCCTGTCCAAGCCAGTGGATG
TTTCCAAGTTTGGTGTGATTTTTGCTGGTGCCCAGAAGAATGTTGGCTCTGCTGGGGTCACCGTGGTGATTGTCCGTGATGACCTGCTGG
GGTTTGCCCTCCGAGAGTGCCCCTCGGTCCTGGAATACAAGGTGCAGGCTGGAAACAGCTCCTTGTACAACACGCCTCCATGTTTCAGTA
GCCAGAGAAGTCCATCACCTGGTCCCAATCATACTTCTAATAGTAGTAATGCATCAAATGCAACAGTTGTACCACAGAATTCTTCTGCCC
GATCCACGTGTTCATTAACGCCTGCACTAGCAGCACACTTCAGTGAAAATCTCATAAAACACGTTCAAGGATGGCCTGCAGATCATGCAG
AGAAGCAGGCATCAAGATTACGCGAAGAAGCGCATAACATGGGAACTATTCACATGTCCGAAATTTGTACTGAATTAAAAAATTTAAGAT
CTTTAGTCCGAGTATGTGAAATTCAAGCAACTTTGCGAGAGCAAAGGATACTATTTTTGAGACAACAAATTAAGGAACTTGAAAAGCTAA
AAAATCAGAATTCCTTCATGGTGTGAAGATGTGAATAATTGCACATGGTTTTGAGAACAGGAACTGTAAATCTGTTGCCCAATCTTAACA
TTTTTGAGCTGCATTTAAGTAGACTTTGGACCGTTAAGCTGGGCAAAGGAAATGACAAGGGGACGGGGTCTGTGAGAGTCAATTCAGGGG
AAAGATACAAGATTGATTTGTAAAACCCTTGAAATGTAGATTTCTTGTAGATGTATCCTTCACGTTGTAAATATGTTTTGTAGAGTGAAG
CCATGGGAAGCCATGTGTAACAGAGCTTAGACATCCAAAACTAATCAATGCTGAGGTGGCTAAATACCTAGCCTTTTACATGTAAACCTG
TCTGCAAAATTAGCTTTTTTAAAAAAAAAAAAAAAAAAATTGGGGGGGTTAATTTATCATTCAGAAATCTTGCATTTTCAAAAATTCAGT
GCAAGCGCCAGGCGATTTGTGTCTAAGGATACGATTTTGAACCATATGGGCAGTGTACAAAATATGAAACAACTGTTTCCACACTTGCAC
CTGATCAAGAGCAGTGCTTCTCCATTTGTTTTGCAGAGAAATGTTTTTCATTTCCCGTGTGTTTCCATTTCCTTCTGAAATTCTGATTTT
ATCCATTTTTTTAAGGCTCCTCTTTATCTCCTTTCTTAAGGCACTGTTGCTATGGCACTTTTCTATAACCTTTTCATTCCTGTGTACAGT
AGCTTAAAATTGCAGTGATTGAGCATAACCTACTTGTTTGTATAAATTATTGAAATCCATTTGCACCCTGTTAAGAATGGACTTAAAAGT
ACTGCTGGACAGGCATGTGTGCTCAAAGTACATTGATTGCTCAAATATAAGGAAATGGCCCAATGAACGTGGTTGTGGGAGGGGAAAGAG

>69433_69433_6_PSAT1-WAC_PSAT1_chr9_80923499_ENST00000376588_WAC_chr10_28905101_ENST00000354911_length(amino acids)=384AA_BP=255
MTHRPGRRTMDAPRQVVNFGPGPAKLPHSVLLEIQKELLDYKGVGISVLEMSHRSSDFAKIINNTENLVRELLAVPDNYKVIFLQGGGCG
QFSAVPLNLIGLKAGRCADYVVTGAWSAKAAEEAKKFGTINIVHPKLGSYTKIPDPSTWNLNPDASYVYYCANETVHGVEFDFIPDVKGA
VLVCDMSSNFLSKPVDVSKFGVIFAGAQKNVGSAGVTVVIVRDDLLGFALRECPSVLEYKVQAGNSSLYNTPPCFSSQRSPSPGPNHTSN
SSNASNATVVPQNSSARSTCSLTPALAAHFSENLIKHVQGWPADHAEKQASRLREEAHNMGTIHMSEICTELKNLRSLVRVCEIQATLRE

--------------------------------------------------------------
>69433_69433_7_PSAT1-WAC_PSAT1_chr9_80923499_ENST00000376588_WAC_chr10_28905101_ENST00000375646_length(transcript)=1566nt_BP=808nt
GGCCAGGAACGCCAGCCGTTCACGCGTTCGGTCCTCCTTGGCTGACTCACCGCCCTGGCCGCCGCACCATGGACGCCCCCAGGCAGGTGG
TCAACTTTGGGCCTGGTCCCGCCAAGCTGCCGCACTCAGTGTTGTTAGAGATACAAAAGGAATTATTAGACTACAAAGGAGTTGGCATTA
GTGTTCTTGAAATGAGTCACAGGTCATCAGATTTTGCCAAGATTATTAACAATACAGAGAATCTTGTGCGGGAATTGCTAGCTGTTCCAG
ACAACTATAAGGTGATTTTTCTGCAAGGAGGTGGGTGCGGCCAGTTCAGTGCTGTCCCCTTAAACCTCATTGGCTTGAAAGCAGGAAGGT
GTGCTGACTATGTGGTGACAGGAGCTTGGTCAGCTAAGGCCGCAGAAGAAGCCAAGAAGTTTGGGACTATAAATATCGTTCACCCTAAAC
TTGGGAGTTATACAAAAATTCCAGATCCAAGCACCTGGAACCTCAACCCAGATGCCTCCTACGTGTATTATTGCGCAAATGAGACGGTGC
ATGGTGTGGAGTTTGACTTTATACCCGATGTCAAGGGAGCAGTACTGGTTTGTGACATGTCCTCAAACTTCCTGTCCAAGCCAGTGGATG
TTTCCAAGTTTGGTGTGATTTTTGCTGGTGCCCAGAAGAATGTTGGCTCTGCTGGGGTCACCGTGGTGATTGTCCGTGATGACCTGCTGG
GGTTTGCCCTCCGAGAGTGCCCCTCGGTCCTGGAATACAAGGTGCAGGCTGGAAACAGCTCCTTGTACAACACGCCTCCATGTTTCAGTA
GCCAGAGAAGTCCATCACCTGGTCCCAATCATACTTCTAATAGTAGTAATGCATCAAATGCAACAGTTGTACCACAGAATTCTTCTGCCC
GATCCACGTGTTCATTAACGCCTGCACTAGCAGCACACTTCAGTGAAAATCTCATAAAACACGTTCAAGGATGGCCTGCAGATCATGCAG
AGAAGCAGGCATCAAGATTACGCGAAGAAGCGCATAACATGGGAACTATTCACATGTCCGAAATTTGTACTGAATTAAAAAATTTAAGAT
CTTTAGTCCGAGTATGTGAAATTCAAGCAACTTTGCGAGAGCAAAGGATACTATTTTTGAGACAACAAATTAAGGAACTTGAAAAGCTAA
AAAATCAGAATTCCTTCATGGTGTGAAGATGTGAATAATTGCACATGGTTTTGAGAACAGGAACTGTAAATCTGTTGCCCAATCTTAACA
TTTTTGAGCTGCATTTAAGTAGACTTTGGACCGTTAAGCTGGGCAAAGGAAATGACAAGGGGACGGGGTCTGTGAGAGTCAATTCAGGGG
AAAGATACAAGATTGATTTGTAAAACCCTTGAAATGTAGATTTCTTGTAGATGTATCCTTCACGTTGTAAATATGTTTTGTAGAGTGAAG
CCATGGGAAGCCATGTGTAACAGAGCTTAGACATCCAAAACTAATCAATGCTGAGGTGGCTAAATACCTAGCCTTTTACATGTAAACCTG

>69433_69433_7_PSAT1-WAC_PSAT1_chr9_80923499_ENST00000376588_WAC_chr10_28905101_ENST00000375646_length(amino acids)=384AA_BP=255
MTHRPGRRTMDAPRQVVNFGPGPAKLPHSVLLEIQKELLDYKGVGISVLEMSHRSSDFAKIINNTENLVRELLAVPDNYKVIFLQGGGCG
QFSAVPLNLIGLKAGRCADYVVTGAWSAKAAEEAKKFGTINIVHPKLGSYTKIPDPSTWNLNPDASYVYYCANETVHGVEFDFIPDVKGA
VLVCDMSSNFLSKPVDVSKFGVIFAGAQKNVGSAGVTVVIVRDDLLGFALRECPSVLEYKVQAGNSSLYNTPPCFSSQRSPSPGPNHTSN
SSNASNATVVPQNSSARSTCSLTPALAAHFSENLIKHVQGWPADHAEKQASRLREEAHNMGTIHMSEICTELKNLRSLVRVCEIQATLRE

--------------------------------------------------------------
>69433_69433_8_PSAT1-WAC_PSAT1_chr9_80923499_ENST00000376588_WAC_chr10_28905101_ENST00000375664_length(transcript)=4702nt_BP=808nt
GGCCAGGAACGCCAGCCGTTCACGCGTTCGGTCCTCCTTGGCTGACTCACCGCCCTGGCCGCCGCACCATGGACGCCCCCAGGCAGGTGG
TCAACTTTGGGCCTGGTCCCGCCAAGCTGCCGCACTCAGTGTTGTTAGAGATACAAAAGGAATTATTAGACTACAAAGGAGTTGGCATTA
GTGTTCTTGAAATGAGTCACAGGTCATCAGATTTTGCCAAGATTATTAACAATACAGAGAATCTTGTGCGGGAATTGCTAGCTGTTCCAG
ACAACTATAAGGTGATTTTTCTGCAAGGAGGTGGGTGCGGCCAGTTCAGTGCTGTCCCCTTAAACCTCATTGGCTTGAAAGCAGGAAGGT
GTGCTGACTATGTGGTGACAGGAGCTTGGTCAGCTAAGGCCGCAGAAGAAGCCAAGAAGTTTGGGACTATAAATATCGTTCACCCTAAAC
TTGGGAGTTATACAAAAATTCCAGATCCAAGCACCTGGAACCTCAACCCAGATGCCTCCTACGTGTATTATTGCGCAAATGAGACGGTGC
ATGGTGTGGAGTTTGACTTTATACCCGATGTCAAGGGAGCAGTACTGGTTTGTGACATGTCCTCAAACTTCCTGTCCAAGCCAGTGGATG
TTTCCAAGTTTGGTGTGATTTTTGCTGGTGCCCAGAAGAATGTTGGCTCTGCTGGGGTCACCGTGGTGATTGTCCGTGATGACCTGCTGG
GGTTTGCCCTCCGAGAGTGCCCCTCGGTCCTGGAATACAAGGTGCAGGCTGGAAACAGCTCCTTGTACAACACGCCTCCATGTTTCAGTA
GCCAGAGAAGTCCATCACCTGGTCCCAATCATACTTCTAATAGTAGTAATGCATCAAATGCAACAGTTGTACCACAGAATTCTTCTGCCC
GATCCACGTGTTCATTAACGCCTGCACTAGCAGCACACTTCAGTGAAAATCTCATAAAACACGTTCAAGGATGGCCTGCAGATCATGCAG
AGAAGCAGGCATCAAGATTACGCGAAGAAGCGCATAACATGGGAACTATTCACATGTCCGAAATTTGTACTGAATTAAAAAATTTAAGAT
CTTTAGTCCGAGTATGTGAAATTCAAGCAACTTTGCGAGAGCAAAGGATACTATTTTTGAGACAACAAATTAAGGAACTTGAAAAGCTAA
AAAATCAGAATTCCTTCATGGTGTGAAGATGTGAATAATTGCACATGGTTTTGAGAACAGGAACTGTAAATCTGTTGCCCAATCTTAACA
TTTTTGAGCTGCATTTAAGTAGACTTTGGACCGTTAAGCTGGGCAAAGGAAATGACAAGGGGACGGGGTCTGTGAGAGTCAATTCAGGGG
AAAGATACAAGATTGATTTGTAAAACCCTTGAAATGTAGATTTCTTGTAGATGTATCCTTCACGTTGTAAATATGTTTTGTAGAGTGAAG
CCATGGGAAGCCATGTGTAACAGAGCTTAGACATCCAAAACTAATCAATGCTGAGGTGGCTAAATACCTAGCCTTTTACATGTAAACCTG
TCTGCAAAATTAGCTTTTTTAAAAAAAAAAAAAAAAAAATTGGGGGGGTTAATTTATCATTCAGAAATCTTGCATTTTCAAAAATTCAGT
GCAAGCGCCAGGCGATTTGTGTCTAAGGATACGATTTTGAACCATATGGGCAGTGTACAAAATATGAAACAACTGTTTCCACACTTGCAC
CTGATCAAGAGCAGTGCTTCTCCATTTGTTTTGCAGAGAAATGTTTTTCATTTCCCGTGTGTTTCCATTTCCTTCTGAAATTCTGATTTT
ATCCATTTTTTTAAGGCTCCTCTTTATCTCCTTTCTTAAGGCACTGTTGCTATGGCACTTTTCTATAACCTTTTCATTCCTGTGTACAGT
AGCTTAAAATTGCAGTGATTGAGCATAACCTACTTGTTTGTATAAATTATTGAAATCCATTTGCACCCTGTTAAGAATGGACTTAAAAGT
ACTGCTGGACAGGCATGTGTGCTCAAAGTACATTGATTGCTCAAATATAAGGAAATGGCCCAATGAACGTGGTTGTGGGAGGGGAAAGAG
GAAACAGAGCTAGTCAGATGTGAATTGTATCTGTTGTAATAAACATGTTAAAACAAACAAAAATTGTTATTTTTCTTTTCCTTCGGTCAG
TGCACATTAGCATTTGAACTACCTGGGGATTCTTTATCAGAACTGTTCTTGTTGAATATTTATACTTAATTGAAATAATTCCTTAAGGGA
GGTTTTGTTTAAAACGTATTAACAGGAAATTGTGTATGAGATATTTAATGAAATAAGAAATTCAACAAGAATGATTAAGTCACTTCCCAA
GTGGTTGTCATTTGTTAAACCCTGGTTTACCTGTCTTGCTATTATGACATTTCATTTGGAAGGATGTTTGTGTTGTAGCTAACTGTTCAA
GTCTGGTGCTGACTGCTGTTCTTAGCCATCACAAAACGCTAAATTTGTGTAATTGGAGCTTCCTGCTGTTATCTGGAAATAGCAGGAAAG
CGCAGCTTTGTATATTGTTTCCTAAAGTATATTAAAATAAAAAAAGAAACTATTGCTACTATAAAATTACCTTGACTTTTTTTTTCCTTT
GCTGAAATATTAGTCACATAGCCTTAGCTTCACACTGCCAGTAATGTATCAAATCACAAGGGTTTCCGCATGAAAAAAATCTTTTCTTCC
CCCACAAAAAAACCTTTACCATCAAAATCTTGCCATCTGATTTAGAAAGGTGTTTCTTCTTCTTCTTCTTTTTTTTCTTTAAATTGGTTT
AGGGTTTTTTGGTGATTTTTTTTTTTTTTTTTTTTCTGTTGGGGCAGATAAGTGCTTCCAAAACTGGCAGCACCAAGGGCTTATTTTTTA
TGTTAGACATCAATGTCAATGTTACTACATTCTCGGATGCTAACATAAATTTTGAAATTGCTCTTGTGCTTTAAGCATATATTGAAAGTA
TGGAAGTTAAATGTTCAGGCTTTTCAGTAAGCTCAAAAAGTTAACTGTAAGCGATAGTGTTGGTGTTTTCTAAAATACAAAAATGTTCCA
GTGTAATTAAAAGGAATTAAAATCTTGAAGATATTTTCCTGTAATTTAAGGATACTTTTTAAATGTAAGAAAAGACATGTCATTAATTTA
TTGTCATGTTTATACCTCTGTGAGATTGTTAACATCTGCTGAATTTAACTAGTGCATGTAAATGAAACCCCAAAGAGCTGTGTGTTCAGC
TAGAAACCTTACTGTATCTTTCCTGGAAAGAAGTGAGCAATTTGTTGTAATAGGCAAATGTTTCCTGATCAGATGGCAATTTGTGATTTA
GGTAAATTTGAATTTGATTTGCTTATAGTCTACTGGTCTGTGTACCTATGTTTTGTTTTTCAAAAAAGTTTACATCCCTAAATGAATTAG
TCACATATATTTAGGAGAAGATGCCTAATTTGGTATTTCTTAATAGTGAATTTTTTTTTTTCTTGAGACAGAGTTTCACTCTTGTTGCCC
AGGCTGGAGTGCAATGGCACGATCTCGGCTCACCGCAACCTCTGCCTCCTGGGTTCAAGCGATTCTCCTGCCTCGGCGTTCCGAGTAGCT
GGGATTACAGGCATGCACCACCACGCCTGGCTAATTTTGTATTTTTAGTAGAGATGGGGTTTCTCCATGTTGGTCAGGCTGGTCTTGAAC
TGCCAACTTCAGGTGATCTGCCTGCCTTGGCCTCCCAAAGTGCTGGGATTACAGGCGTGAGCCACCGCTCCTGGCCAGTAGTGAATTTTT
AAACACAGAAAATCTAAAATTTTGTGGAAATATTTTAAATATTGCACCTTAATACAAGGTATCCAGCTCCTAACCTTAACTAGGGAATAT
CTATTAAAATAAGCATAATGTTCTGGACTAGAGTATTCCTTATCTAGTTGGTTATGGATTTGAACATGTACCTTGGTTTAGATACTTTGA
AAATAGAAGTACTGAATAGCCTCTAGGGAACTTGAGTGGCCTTTCCCTCCCCCTGCCCCCCCCCCCCCCCCCCCGTTTTAAAAGATCAGT
AGTCTCTATTCAAACTTTTAAAATGTCGTGGTATTGTAACAATATATTTGATGAAAGAAGGTTACAGACTCCCCTGAAGAACCAGCTTTC
CTACGCTTTTTATTTTTCTAACTTGTCTAACCTGATTTTAAAATGACTGCAATTCCAGACTAAAAACATGCTTCAGCCCTGTTTCAAGAC
ATTATGCTTCTTTTAACAGTCCAAATTAGTAGTTTTATTTTTCTTCTAAATCTTTGTTTCACACTTGTAAAATCTTGGGAAGGAGGTTCT
TAAAACTTTGCCAGGAATTGTTACCCATTTCCAAAAACAGTTTATTATGTTCAAAAACCACCATATCTTTGAGGGACTGTTTGAAAGGGG
AGAGGGCAACGCGGGAAATAATTCACTCTGCGCACCGGAACTATTGTAGTTCAGGACTTCCAGCTACTGTATTTAGATGTTGGGTTTGAA
TATACAGATTTCTTTTCAATACCTGTAAATATGGCTATATTCTTGTATTTGTACGGGAGTGTACAAAATGACACTGAAAAGTAATAAATA
TGTTTTGACTATATTGTGCAGTTATTTCAGAACTGTGTTTTGAAAGTCTTAGAATGCATAATTTGCATTTGAGTAAGGAAATTTAAAATA

>69433_69433_8_PSAT1-WAC_PSAT1_chr9_80923499_ENST00000376588_WAC_chr10_28905101_ENST00000375664_length(amino acids)=384AA_BP=255
MTHRPGRRTMDAPRQVVNFGPGPAKLPHSVLLEIQKELLDYKGVGISVLEMSHRSSDFAKIINNTENLVRELLAVPDNYKVIFLQGGGCG
QFSAVPLNLIGLKAGRCADYVVTGAWSAKAAEEAKKFGTINIVHPKLGSYTKIPDPSTWNLNPDASYVYYCANETVHGVEFDFIPDVKGA
VLVCDMSSNFLSKPVDVSKFGVIFAGAQKNVGSAGVTVVIVRDDLLGFALRECPSVLEYKVQAGNSSLYNTPPCFSSQRSPSPGPNHTSN
SSNASNATVVPQNSSARSTCSLTPALAAHFSENLIKHVQGWPADHAEKQASRLREEAHNMGTIHMSEICTELKNLRSLVRVCEIQATLRE

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Fusion Gene PPI Analysis for PSAT1-WAC

Go to ChiPPI (Chimeric Protein-Protein interactions) to see the chimeric PPI interaction in
ChiPPI page.

Protein-protein interactors with each fusion partner protein in wild-type (BIOGRID-3.4.160)

Hgene

Hgene's interactors

Tgene

Tgene's interactors

- Retained PPIs in in-frame fusion.

Partner

Gene

Hbp

Tbp

ENST

Strand

BPexon

TotalExon

Protein feature loci

*BPloci

TotalLen

Still interaction with

- Lost PPIs in in-frame fusion.

Partner

Gene

Hbp

Tbp

ENST

Strand

BPexon

TotalExon

Protein feature loci

*BPloci

TotalLen

Interaction lost with

- Retained PPIs, but lost function due to frame-shift fusion.

Partner

Gene

Hbp

Tbp

ENST

Strand

BPexon

TotalExon

Protein feature loci

*BPloci

TotalLen

Interaction lost with

Top

Related Drugs for PSAT1-WAC

Drugs targeting genes involved in this fusion gene.
(DrugBank Version 5.1.8 2021-05-08)

Partner

Gene

UniProtAcc

DrugBank ID

Drug name

Drug activity

Drug type

Drug status

Top

Related Diseases for PSAT1-WAC

Diseases associated with fusion partners.
(DisGeNet 4.0)

Partner

Gene

Disease ID

Disease name

# pubmeds

Source