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Center for Computational Systems Medicine
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Fusion Gene Summary

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Fusion Gene ORF analysis

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Fusion Genomic Features

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Fusion Protein Features

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Fusion Gene Sequence

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Fusion Gene PPI analysis

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Related Drugs

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Related Diseases

Fusion gene:ASAP1-CLVS1 (FusionGDB2 ID:6953)

Fusion Gene Summary for ASAP1-CLVS1

check button Fusion gene summary
Fusion gene informationFusion gene name: ASAP1-CLVS1
Fusion gene ID: 6953
HgeneTgene
Gene symbol

ASAP1

CLVS1

Gene ID

50807

157807

Gene nameArfGAP with SH3 domain, ankyrin repeat and PH domain 1clavesin 1
SynonymsAMAP1|CENTB4|DDEF1|PAG2|PAP|ZG14PC6orf212L|CRALBPL|RLBP1L1
Cytomap

8q24.21-q24.22

8q12.2-q12.3

Type of geneprotein-codingprotein-coding
Descriptionarf-GAP with SH3 domain, ANK repeat and PH domain-containing protein 1130 kDa phosphatidylinositol 4,5-biphosphate-dependent ARF1 GTPase-activating protein130 kDa phosphatidylinositol 4,5-bisphosphate-dependent ARF1 GTPase-activating proteinADP-ribosylclavesin-1clathrin vesicle-associated Sec14 protein 1retinaldehyde-binding protein 1-like 1
Modification date2020032720200313
UniProtAcc

Q9ULH1

Q8IUQ0

Ensembl transtripts involved in fusion geneENST00000357668, ENST00000518721, 
ENST00000520625, 		ENST00000325897, 
ENST00000518592, ENST00000518858, 
ENST00000519846, 
Fusion gene scores* DoF score25 X 17 X 13=552515 X 16 X 12=2880
# samples 2820
** MAII scorelog2(28/5525*10)=-4.30247573222119
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0		log2(20/2880*10)=-3.84799690655495
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0
Context

PubMed: ASAP1 [Title/Abstract] AND CLVS1 [Title/Abstract] AND fusion [Title/Abstract]

Most frequent breakpointASAP1(131370263)-CLVS1(62366700), # samples:3
Anticipated loss of major functional domain due to fusion event.ASAP1-CLVS1 seems lost the major protein functional domain in Hgene partner, which is a essential gene due to the frame-shifted ORF.
* DoF score (Degree of Frequency) = # partners X # break points X # cancer types
** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10)

check button Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez
PartnerGeneGO IDGO termPubMed ID

check buttonFusion gene breakpoints across ASAP1 (5'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.
all structure

check buttonFusion gene breakpoints across CLVS1 (3'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.
all structure

check button Fusion gene information from two resources (ChiTars 5.0 and ChimerDB 4.0)
* All genome coordinats were lifted-over on hg19.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
SourceDiseaseSampleHgeneHchrHbpHstrandTgeneTchrTbpTstrand
ChimerDB4BRCATCGA-C8-A27A-01AASAP1chr8

131370263

-CLVS1chr8

62366700

+
ChimerDB4BRCATCGA-C8-A27A-01AASAP1chr8

131414131

-CLVS1chr8

62366700

+
ChimerDB4BRCATCGA-C8-A27AASAP1chr8

131370262

-CLVS1chr8

62366699

+
ChimerDB4BRCATCGA-C8-A27AASAP1chr8

131414130

-CLVS1chr8

62366699

+


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Fusion Gene ORF analysis for ASAP1-CLVS1

check button Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
ORFHenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrand
5CDS-5UTRENST00000357668ENST00000325897ASAP1chr8

131370263

-CLVS1chr8

62366700

+
5CDS-5UTRENST00000357668ENST00000325897ASAP1chr8

131414131

-CLVS1chr8

62366700

+
5CDS-5UTRENST00000357668ENST00000325897ASAP1chr8

131370262

-CLVS1chr8

62366699

+
5CDS-5UTRENST00000357668ENST00000325897ASAP1chr8

131414130

-CLVS1chr8

62366699

+
5CDS-5UTRENST00000357668ENST00000518592ASAP1chr8

131370263

-CLVS1chr8

62366700

+
5CDS-5UTRENST00000357668ENST00000518592ASAP1chr8

131414131

-CLVS1chr8

62366700

+
5CDS-5UTRENST00000357668ENST00000518592ASAP1chr8

131370262

-CLVS1chr8

62366699

+
5CDS-5UTRENST00000357668ENST00000518592ASAP1chr8

131414130

-CLVS1chr8

62366699

+
5CDS-5UTRENST00000518721ENST00000325897ASAP1chr8

131370263

-CLVS1chr8

62366700

+
5CDS-5UTRENST00000518721ENST00000325897ASAP1chr8

131414131

-CLVS1chr8

62366700

+
5CDS-5UTRENST00000518721ENST00000325897ASAP1chr8

131370262

-CLVS1chr8

62366699

+
5CDS-5UTRENST00000518721ENST00000325897ASAP1chr8

131414130

-CLVS1chr8

62366699

+
5CDS-5UTRENST00000518721ENST00000518592ASAP1chr8

131370263

-CLVS1chr8

62366700

+
5CDS-5UTRENST00000518721ENST00000518592ASAP1chr8

131414131

-CLVS1chr8

62366700

+
5CDS-5UTRENST00000518721ENST00000518592ASAP1chr8

131370262

-CLVS1chr8

62366699

+
5CDS-5UTRENST00000518721ENST00000518592ASAP1chr8

131414130

-CLVS1chr8

62366699

+
5CDS-intronENST00000357668ENST00000518858ASAP1chr8

131370263

-CLVS1chr8

62366700

+
5CDS-intronENST00000357668ENST00000518858ASAP1chr8

131414131

-CLVS1chr8

62366700

+
5CDS-intronENST00000357668ENST00000518858ASAP1chr8

131370262

-CLVS1chr8

62366699

+
5CDS-intronENST00000357668ENST00000518858ASAP1chr8

131414130

-CLVS1chr8

62366699

+
5CDS-intronENST00000518721ENST00000518858ASAP1chr8

131370263

-CLVS1chr8

62366700

+
5CDS-intronENST00000518721ENST00000518858ASAP1chr8

131414131

-CLVS1chr8

62366700

+
5CDS-intronENST00000518721ENST00000518858ASAP1chr8

131370262

-CLVS1chr8

62366699

+
5CDS-intronENST00000518721ENST00000518858ASAP1chr8

131414130

-CLVS1chr8

62366699

+
5UTR-3CDSENST00000520625ENST00000519846ASAP1chr8

131414131

-CLVS1chr8

62366700

+
5UTR-3CDSENST00000520625ENST00000519846ASAP1chr8

131414130

-CLVS1chr8

62366699

+
5UTR-5UTRENST00000520625ENST00000325897ASAP1chr8

131414131

-CLVS1chr8

62366700

+
5UTR-5UTRENST00000520625ENST00000325897ASAP1chr8

131414130

-CLVS1chr8

62366699

+
5UTR-5UTRENST00000520625ENST00000518592ASAP1chr8

131414131

-CLVS1chr8

62366700

+
5UTR-5UTRENST00000520625ENST00000518592ASAP1chr8

131414130

-CLVS1chr8

62366699

+
5UTR-intronENST00000520625ENST00000518858ASAP1chr8

131414131

-CLVS1chr8

62366700

+
5UTR-intronENST00000520625ENST00000518858ASAP1chr8

131414130

-CLVS1chr8

62366699

+
Frame-shiftENST00000518721ENST00000519846ASAP1chr8

131370263

-CLVS1chr8

62366700

+
Frame-shiftENST00000518721ENST00000519846ASAP1chr8

131370262

-CLVS1chr8

62366699

+
In-frameENST00000357668ENST00000519846ASAP1chr8

131370263

-CLVS1chr8

62366700

+
In-frameENST00000357668ENST00000519846ASAP1chr8

131414131

-CLVS1chr8

62366700

+
In-frameENST00000357668ENST00000519846ASAP1chr8

131370262

-CLVS1chr8

62366699

+
In-frameENST00000357668ENST00000519846ASAP1chr8

131414130

-CLVS1chr8

62366699

+
In-frameENST00000518721ENST00000519846ASAP1chr8

131414131

-CLVS1chr8

62366700

+
In-frameENST00000518721ENST00000519846ASAP1chr8

131414130

-CLVS1chr8

62366699

+
intron-3CDSENST00000520625ENST00000519846ASAP1chr8

131370263

-CLVS1chr8

62366700

+
intron-3CDSENST00000520625ENST00000519846ASAP1chr8

131370262

-CLVS1chr8

62366699

+
intron-5UTRENST00000520625ENST00000325897ASAP1chr8

131370263

-CLVS1chr8

62366700

+
intron-5UTRENST00000520625ENST00000325897ASAP1chr8

131370262

-CLVS1chr8

62366699

+
intron-5UTRENST00000520625ENST00000518592ASAP1chr8

131370263

-CLVS1chr8

62366700

+
intron-5UTRENST00000520625ENST00000518592ASAP1chr8

131370262

-CLVS1chr8

62366699

+
intron-intronENST00000520625ENST00000518858ASAP1chr8

131370263

-CLVS1chr8

62366700

+
intron-intronENST00000520625ENST00000518858ASAP1chr8

131370262

-CLVS1chr8

62366699

+

check buttonORFfinder result based on the fusion transcript sequence of in-frame fusion genes.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandSeq length
(transcript)		BP loci
(transcript)		Predicted start
(transcript)		Predicted stop
(transcript)		Seq length
(amino acids)
ENST00000357668ASAP1chr8131370263-ENST00000519846CLVS1chr862366700+273421428648206
ENST00000357668ASAP1chr8131370262-ENST00000519846CLVS1chr862366699+273421428648206
ENST00000357668ASAP1chr8131414130-ENST00000519846CLVS1chr862366699+26078721521166
ENST00000518721ASAP1chr8131414130-ENST00000519846CLVS1chr862366699+2807287959375194
ENST00000357668ASAP1chr8131414131-ENST00000519846CLVS1chr862366700+26078721521166
ENST00000518721ASAP1chr8131414131-ENST00000519846CLVS1chr862366700+2807287959375194

check buttonDeepORF prediction of the coding potential based on the fusion transcript sequence of in-frame fusion genes. DeepORF is a coding potential classifier based on convolutional neural network by comparing the real Ribo-seq data. If the no-coding score < 0.5 and coding score > 0.5, then the in-frame fusion transcript is predicted as being likely translated.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandNo-coding scoreCoding score
ENST00000357668ENST00000519846ASAP1chr8131370263-CLVS1chr862366700+0.0053107660.9946892
ENST00000357668ENST00000519846ASAP1chr8131370262-CLVS1chr862366699+0.0053107660.9946892
ENST00000357668ENST00000519846ASAP1chr8131414130-CLVS1chr862366699+0.0145959130.9854041
ENST00000518721ENST00000519846ASAP1chr8131414130-CLVS1chr862366699+0.0057867250.9942133
ENST00000357668ENST00000519846ASAP1chr8131414131-CLVS1chr862366700+0.0145959130.9854041
ENST00000518721ENST00000519846ASAP1chr8131414131-CLVS1chr862366700+0.0057867250.9942133

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Fusion Genomic Features for ASAP1-CLVS1


check buttonFusionAI prediction of the potential fusion gene breakpoint based on the pre-mature RNA sequence context (+/- 5kb of individual partner genes, total 20kb length sequence). FusionAI is a fusion gene breakpoint classifier based on convolutional neural network by comparing the fusion positive and negative sequence context of ~ 20K fusion gene data. From here, we can have the relative potentency of the 20K genomic sequence how individual sequnce will be likely used as the gene fusion breakpoints.
HgeneHchrHbpHstrandTgeneTchrTbpTstrand1-pp (fusion gene breakpoint)
ASAP1chr8131414130-CLVS1chr862366699+0.0105231370.9894769
ASAP1chr8131414130-CLVS1chr862366699+0.0105231370.9894769
ASAP1chr8131370262-CLVS1chr862366699+4.31E-050.99995697
ASAP1chr8131370262-CLVS1chr862366699+4.31E-050.99995697
ASAP1chr8131414130-CLVS1chr862366699+0.0105231370.9894769
ASAP1chr8131414130-CLVS1chr862366699+0.0105231370.9894769
ASAP1chr8131370262-CLVS1chr862366699+4.31E-050.99995697
ASAP1chr8131370262-CLVS1chr862366699+4.31E-050.99995697

check buttonDistribution of 44 human genomic features loci across 20kb length fusion breakpoint regions. We integrated a total of 44 different types of human genomic feature loci information across five big categories including virus integration sites, repeats, structural variants, chromatin states, and gene expression regulation. More details are in help page.
genomic feature

check buttonDistribution of 44 human genomic features loci across 20kb length fusion breakpoint regions that are ovelapped with the top 1% feature importance score regions. More details are in help page.
genomic feature of top 1%

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Fusion Protein Features for ASAP1-CLVS1


check button Four levels of functional features of fusion genes
Go to FGviewer search page for the most frequent breakpoint (https://ccsmweb.uth.edu/FGviewer/chr8:131370263/chr8:62366700)
- FGviewer provides the online visualization of the retention search of the protein functional features across DNA, RNA, protein, and pathological levels.
- How to search
1. Put your fusion gene symbol.
2. Press the tab key until there will be shown the breakpoint information filled.
4. Go down and press 'Search' tab twice.
4. Go down to have the hyperlink of the search result.
5. Click the hyperlink.
6. See the FGviewer result for your fusion gene.
FGviewer

check buttonMain function of each fusion partner protein. (from UniProt)
HgeneTgene
ASAP1

Q9ULH1

CLVS1

Q8IUQ0

FUNCTION: Possesses phosphatidylinositol 4,5-bisphosphate-dependent GTPase-activating protein activity for ARF1 (ADP ribosylation factor 1) and ARF5 and a lesser activity towards ARF6. May coordinate membrane trafficking with cell growth or actin cytoskeleton remodeling by binding to both SRC and PIP2. May function as a signal transduction protein involved in the differentiation of fibroblasts into adipocytes and possibly other cell types (By similarity). Plays a role in ciliogenesis. {ECO:0000250, ECO:0000269|PubMed:20393563}.FUNCTION: Required for normal morphology of late endosomes and/or lysosomes in neurons (By similarity). Binds phosphatidylinositol 3,5-bisphosphate (PtdIns(3,5)P2). {ECO:0000250, ECO:0000269|PubMed:19651769}.

check buttonRetention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at

download page


* Minus value of BPloci means that the break pointn is located before the CDS.
- In-frame and retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note

- In-frame and not-retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
HgeneASAP1chr8:131370262chr8:62366699ENST00000357668-229783_993621130.0Compositional biasNote=Pro-rich
HgeneASAP1chr8:131370262chr8:62366699ENST00000518721-330783_993621130.0Compositional biasNote=Pro-rich
HgeneASAP1chr8:131370263chr8:62366700ENST00000357668-229783_993621130.0Compositional biasNote=Pro-rich
HgeneASAP1chr8:131370263chr8:62366700ENST00000518721-330783_993621130.0Compositional biasNote=Pro-rich
HgeneASAP1chr8:131414130chr8:62366699ENST00000357668-129783_993191130.0Compositional biasNote=Pro-rich
HgeneASAP1chr8:131414130chr8:62366699ENST00000518721-230783_993191130.0Compositional biasNote=Pro-rich
HgeneASAP1chr8:131414131chr8:62366700ENST00000357668-129783_993191130.0Compositional biasNote=Pro-rich
HgeneASAP1chr8:131414131chr8:62366700ENST00000518721-230783_993191130.0Compositional biasNote=Pro-rich
HgeneASAP1chr8:131370262chr8:62366699ENST00000357668-2291067_1129621130.0DomainSH3
HgeneASAP1chr8:131370262chr8:62366699ENST00000357668-229324_416621130.0DomainPH
HgeneASAP1chr8:131370262chr8:62366699ENST00000357668-229439_560621130.0DomainArf-GAP
HgeneASAP1chr8:131370262chr8:62366699ENST00000518721-3301067_1129621130.0DomainSH3
HgeneASAP1chr8:131370262chr8:62366699ENST00000518721-330324_416621130.0DomainPH
HgeneASAP1chr8:131370262chr8:62366699ENST00000518721-330439_560621130.0DomainArf-GAP
HgeneASAP1chr8:131370263chr8:62366700ENST00000357668-2291067_1129621130.0DomainSH3
HgeneASAP1chr8:131370263chr8:62366700ENST00000357668-229324_416621130.0DomainPH
HgeneASAP1chr8:131370263chr8:62366700ENST00000357668-229439_560621130.0DomainArf-GAP
HgeneASAP1chr8:131370263chr8:62366700ENST00000518721-3301067_1129621130.0DomainSH3
HgeneASAP1chr8:131370263chr8:62366700ENST00000518721-330324_416621130.0DomainPH
HgeneASAP1chr8:131370263chr8:62366700ENST00000518721-330439_560621130.0DomainArf-GAP
HgeneASAP1chr8:131414130chr8:62366699ENST00000357668-1291067_1129191130.0DomainSH3
HgeneASAP1chr8:131414130chr8:62366699ENST00000357668-129324_416191130.0DomainPH
HgeneASAP1chr8:131414130chr8:62366699ENST00000357668-129439_560191130.0DomainArf-GAP
HgeneASAP1chr8:131414130chr8:62366699ENST00000518721-2301067_1129191130.0DomainSH3
HgeneASAP1chr8:131414130chr8:62366699ENST00000518721-230324_416191130.0DomainPH
HgeneASAP1chr8:131414130chr8:62366699ENST00000518721-230439_560191130.0DomainArf-GAP
HgeneASAP1chr8:131414131chr8:62366700ENST00000357668-1291067_1129191130.0DomainSH3
HgeneASAP1chr8:131414131chr8:62366700ENST00000357668-129324_416191130.0DomainPH
HgeneASAP1chr8:131414131chr8:62366700ENST00000357668-129439_560191130.0DomainArf-GAP
HgeneASAP1chr8:131414131chr8:62366700ENST00000518721-2301067_1129191130.0DomainSH3
HgeneASAP1chr8:131414131chr8:62366700ENST00000518721-230324_416191130.0DomainPH
HgeneASAP1chr8:131414131chr8:62366700ENST00000518721-230439_560191130.0DomainArf-GAP
HgeneASAP1chr8:131370262chr8:62366699ENST00000357668-229600_632621130.0RepeatNote=ANK 1
HgeneASAP1chr8:131370262chr8:62366699ENST00000357668-229636_665621130.0RepeatNote=ANK 2
HgeneASAP1chr8:131370262chr8:62366699ENST00000518721-330600_632621130.0RepeatNote=ANK 1
HgeneASAP1chr8:131370262chr8:62366699ENST00000518721-330636_665621130.0RepeatNote=ANK 2
HgeneASAP1chr8:131370263chr8:62366700ENST00000357668-229600_632621130.0RepeatNote=ANK 1
HgeneASAP1chr8:131370263chr8:62366700ENST00000357668-229636_665621130.0RepeatNote=ANK 2
HgeneASAP1chr8:131370263chr8:62366700ENST00000518721-330600_632621130.0RepeatNote=ANK 1
HgeneASAP1chr8:131370263chr8:62366700ENST00000518721-330636_665621130.0RepeatNote=ANK 2
HgeneASAP1chr8:131414130chr8:62366699ENST00000357668-129600_632191130.0RepeatNote=ANK 1
HgeneASAP1chr8:131414130chr8:62366699ENST00000357668-129636_665191130.0RepeatNote=ANK 2
HgeneASAP1chr8:131414130chr8:62366699ENST00000518721-230600_632191130.0RepeatNote=ANK 1
HgeneASAP1chr8:131414130chr8:62366699ENST00000518721-230636_665191130.0RepeatNote=ANK 2
HgeneASAP1chr8:131414131chr8:62366700ENST00000357668-129600_632191130.0RepeatNote=ANK 1
HgeneASAP1chr8:131414131chr8:62366700ENST00000357668-129636_665191130.0RepeatNote=ANK 2
HgeneASAP1chr8:131414131chr8:62366700ENST00000518721-230600_632191130.0RepeatNote=ANK 1
HgeneASAP1chr8:131414131chr8:62366700ENST00000518721-230636_665191130.0RepeatNote=ANK 2
HgeneASAP1chr8:131370262chr8:62366699ENST00000357668-229454_477621130.0Zinc fingerC4-type
HgeneASAP1chr8:131370262chr8:62366699ENST00000518721-330454_477621130.0Zinc fingerC4-type
HgeneASAP1chr8:131370263chr8:62366700ENST00000357668-229454_477621130.0Zinc fingerC4-type
HgeneASAP1chr8:131370263chr8:62366700ENST00000518721-330454_477621130.0Zinc fingerC4-type
HgeneASAP1chr8:131414130chr8:62366699ENST00000357668-129454_477191130.0Zinc fingerC4-type
HgeneASAP1chr8:131414130chr8:62366699ENST00000518721-230454_477191130.0Zinc fingerC4-type
HgeneASAP1chr8:131414131chr8:62366700ENST00000357668-129454_477191130.0Zinc fingerC4-type
HgeneASAP1chr8:131414131chr8:62366700ENST00000518721-230454_477191130.0Zinc fingerC4-type
TgeneCLVS1chr8:131370262chr8:62366699ENST0000032589726118_279210355.0DomainCRAL-TRIO
TgeneCLVS1chr8:131370262chr8:62366699ENST0000051984637118_279210355.0DomainCRAL-TRIO
TgeneCLVS1chr8:131370263chr8:62366700ENST0000032589726118_279210355.0DomainCRAL-TRIO
TgeneCLVS1chr8:131370263chr8:62366700ENST0000051984637118_279210355.0DomainCRAL-TRIO
TgeneCLVS1chr8:131414130chr8:62366699ENST0000032589726118_279210355.0DomainCRAL-TRIO
TgeneCLVS1chr8:131414130chr8:62366699ENST0000051984637118_279210355.0DomainCRAL-TRIO
TgeneCLVS1chr8:131414131chr8:62366700ENST0000032589726118_279210355.0DomainCRAL-TRIO
TgeneCLVS1chr8:131414131chr8:62366700ENST0000051984637118_279210355.0DomainCRAL-TRIO


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Fusion Gene Sequence for ASAP1-CLVS1


check button For in-frame fusion transcripts, we provide the fusion transcript sequences and fusion amino acid sequences. To have fusion amino acid sequence, we ran ORFfinder and chose the longest ORF among the all predicted ones.
>6953_6953_1_ASAP1-CLVS1_ASAP1_chr8_131370262_ENST00000357668_CLVS1_chr8_62366699_ENST00000519846_length(transcript)=2734nt_BP=214nt
GGTCGTTTTCTGATGTGACGGCTGAGACATGAGATCTTCAGCCTCCAGGCTCTCCAGTTTTTCGTCGAGAGATTCACTATGGAATCGGAT
GCCGGACCAGATCTCTGTCTCGGAGTTCATCGCCGAGACCACCGAGGACTACAACTCGCCCACCACGTCCAGCTTCACCACGCGGCTGCA
CAACTGCAGGAACACCGTCACGCTGCTGGAGGAGGACAGCTTTCCTGCCCGCTTTGGAGGAGTCCACTTTGTCAACCAGCCCTGGTACAT
TCATGCCCTCTACACACTCATCAAGCCATTTCTTAAAGACAAGACCAGGAAACGGATTTTCCTGCATGGAAACAATTTAAACAGCCTTCA
CCAGCTAATACACCCTGAATTTTTGCCCTCTGAATTTGGAGGAACTCTTCCTCCTTATGACATGGGAACTTGGGCCCGGACGTTACTCGG
TCCCGACTACAGCGATGAAAATGACTATACTCACACATCCTATAATGCAATGCACGTGAAGCATACGTCCTCGAATCTGGAGAGAGAATG
CTCACCCAAGCTGATGAAAAGATCTCAGTCTGTGGTAGAAGCTGGGACCCTGAAACATGAGGAGAAGGGAGAGAATGAGAACACCCAGCC
ACTCCTGGCTCTGGACTGAACCCTGAGTCACCCCAATGCTCCTGCACACTGGCCTTCAGTGGTATCAGCCACCCAGGAAGCACATGCACA
ACTGACCCATGCAGACACGTGTGTTCTGCTTGACACAAGGTCCTCCACTCCTGAACCCCTGCAGTGACTGTCACCAGCCATCGGTCTGAG
CAGCCAAAGTTGGACAAAGACTTGAGAGATGCTTTTTTTTTCCCCCAGTGAGGGGACTGGAGGATGATGCAAGGCATTTATGTAAAAAAG
ATTCTCCCTCCTTTCATATTTATTGTAGTAAATTGAAAAAATAAAGACTAAATTTGATGGACACACTGCATTAGGACAAGAATTTTTCTG
AGGTATCACACAGGGACCCTCTCCAGTTTTTGAAAATTAAGTGCATTTCCAAGTAAATGTATCAGAGTTAAACTGTACAGACACCACTGT
CAAGTTTCATGTAGTACAAAGCCCTGAGACAATAGTATCTCCAGTAATTTCCATTCTTACTGAATTATTTCCTTTGACCTCATCACCAGC
ATCGAATTGTTCAGCCTAAGAGCATGTTCTCATAGGTCTGGGTATTTGCAAAGTTTGCTTATTTTGATGATATCCTGCAAAAAATTATTT
TGATGTCACATCTCTTGTCAGGTCACTAGCTGACTGTCATGAGCTGACGTTAAAGGAAGACACATGGACGTGAAATACGATTATTTCATC
TGAGCAATGTGAGTTACCACAGGCAGCTCAAAAGCCCATTAGTGCAGCATGTGTCTGCAGAGGAGATGTCTCATGAAAATCACATGTCAG
TGATTAATGAATCCATTCCAGTTGCCTCAACTGGGTCACTACAGCAAAGAAAAGTGCTATCAAACCATTTACCCTTGCCCCCACAACCCT
CCTGCAACCATTAAAGATGTGGAGAAAGACCATGGTTGTTGCTGAGAGGGTAAATATTCAATCATGGAGCATGACCCATATGGATGGCTA
AATATGCAAGTACTGAAGTAAGAGAAGACTAGAAATGCAGGATGAAATGTCAAAGGTCATTTTATTTACCTAGTCTCCTTAGAAATGGAG
TCCCCAACTACTCATTCAAAAGAAATCAGACATAAAATAAACAGACATCATATATGATATCCTTACTTGTGCCATGTTTTCCAAGACCAG
TGCATATTTTTAGACATCTCTTATTCGCCCAGCCATCTGCATGACATGGGTATTTATTAGTATTACCAGTTGGTGCTCAAAGTCAAACAA
AAATATTTTAGTTAATAATGGGCAGTAAAATATGATTTTACATTATTTTAAATATTTGGGAGAGTTAATTTGTTAGCTAAATAATTCAAG
GGAAAGAGATTATTCAACTGGTCATAATCACCCCTGATAATATTATTACTAATCTTAATTATTTATTACATCATCTCTTTCTCAATGGAT
CTAATGTTTTAATTTTTTCCCCTATTGGTAGAGAACAATAACAGAAGTAATTTTTATATTATACACTTGGAGAAATAAAGTTGAAACAGA
ATTAAAAATATTTCTCAAACAACTGTATCACAATATAAATTAAACTAATTCATTTTTGTGTAGACATACGAAATCACAAAAATAATAACA
CTGAAATAATTCTACCAATGCAGTGATGGAAACACTTTTCTTATGTACCAAGACATAGATAGGTAAGAGAAATAAAGAATTGAAGTGAAT
TAGAAAATCCATTTTATTGCTTGGGTTTAAAATAGTTGTGGGATACAAGTATTTACAATGCTATTGGAGTCAATTATTGACAACACTTTG
CAACAGTAATACCATTTCTAGCTTTTCAATTGGCAATACTTAGAACCTTACTGTAGTGACCTGATTTTAAATACCATATTATATTTACTA
AGTTAAGAGCTAGTTTTTACTCTCTTCCATAATTTCATTACATGAATGTAAGATGATGGCTCAAAAATGACGACTTATAGTTTGAATTTA
TGTGTATGCAATATACATATGAGAACCAAATTCAACAAGTGACATGAATGTTACTACATGAACATTGAATTGTATTGCCCTTGTCAGTTA

>6953_6953_1_ASAP1-CLVS1_ASAP1_chr8_131370262_ENST00000357668_CLVS1_chr8_62366699_ENST00000519846_length(amino acids)=206AA_BP=62
MRSSASRLSSFSSRDSLWNRMPDQISVSEFIAETTEDYNSPTTSSFTTRLHNCRNTVTLLEEDSFPARFGGVHFVNQPWYIHALYTLIKP
FLKDKTRKRIFLHGNNLNSLHQLIHPEFLPSEFGGTLPPYDMGTWARTLLGPDYSDENDYTHTSYNAMHVKHTSSNLERECSPKLMKRSQ

--------------------------------------------------------------
>6953_6953_2_ASAP1-CLVS1_ASAP1_chr8_131370263_ENST00000357668_CLVS1_chr8_62366700_ENST00000519846_length(transcript)=2734nt_BP=214nt
GGTCGTTTTCTGATGTGACGGCTGAGACATGAGATCTTCAGCCTCCAGGCTCTCCAGTTTTTCGTCGAGAGATTCACTATGGAATCGGAT
GCCGGACCAGATCTCTGTCTCGGAGTTCATCGCCGAGACCACCGAGGACTACAACTCGCCCACCACGTCCAGCTTCACCACGCGGCTGCA
CAACTGCAGGAACACCGTCACGCTGCTGGAGGAGGACAGCTTTCCTGCCCGCTTTGGAGGAGTCCACTTTGTCAACCAGCCCTGGTACAT
TCATGCCCTCTACACACTCATCAAGCCATTTCTTAAAGACAAGACCAGGAAACGGATTTTCCTGCATGGAAACAATTTAAACAGCCTTCA
CCAGCTAATACACCCTGAATTTTTGCCCTCTGAATTTGGAGGAACTCTTCCTCCTTATGACATGGGAACTTGGGCCCGGACGTTACTCGG
TCCCGACTACAGCGATGAAAATGACTATACTCACACATCCTATAATGCAATGCACGTGAAGCATACGTCCTCGAATCTGGAGAGAGAATG
CTCACCCAAGCTGATGAAAAGATCTCAGTCTGTGGTAGAAGCTGGGACCCTGAAACATGAGGAGAAGGGAGAGAATGAGAACACCCAGCC
ACTCCTGGCTCTGGACTGAACCCTGAGTCACCCCAATGCTCCTGCACACTGGCCTTCAGTGGTATCAGCCACCCAGGAAGCACATGCACA
ACTGACCCATGCAGACACGTGTGTTCTGCTTGACACAAGGTCCTCCACTCCTGAACCCCTGCAGTGACTGTCACCAGCCATCGGTCTGAG
CAGCCAAAGTTGGACAAAGACTTGAGAGATGCTTTTTTTTTCCCCCAGTGAGGGGACTGGAGGATGATGCAAGGCATTTATGTAAAAAAG
ATTCTCCCTCCTTTCATATTTATTGTAGTAAATTGAAAAAATAAAGACTAAATTTGATGGACACACTGCATTAGGACAAGAATTTTTCTG
AGGTATCACACAGGGACCCTCTCCAGTTTTTGAAAATTAAGTGCATTTCCAAGTAAATGTATCAGAGTTAAACTGTACAGACACCACTGT
CAAGTTTCATGTAGTACAAAGCCCTGAGACAATAGTATCTCCAGTAATTTCCATTCTTACTGAATTATTTCCTTTGACCTCATCACCAGC
ATCGAATTGTTCAGCCTAAGAGCATGTTCTCATAGGTCTGGGTATTTGCAAAGTTTGCTTATTTTGATGATATCCTGCAAAAAATTATTT
TGATGTCACATCTCTTGTCAGGTCACTAGCTGACTGTCATGAGCTGACGTTAAAGGAAGACACATGGACGTGAAATACGATTATTTCATC
TGAGCAATGTGAGTTACCACAGGCAGCTCAAAAGCCCATTAGTGCAGCATGTGTCTGCAGAGGAGATGTCTCATGAAAATCACATGTCAG
TGATTAATGAATCCATTCCAGTTGCCTCAACTGGGTCACTACAGCAAAGAAAAGTGCTATCAAACCATTTACCCTTGCCCCCACAACCCT
CCTGCAACCATTAAAGATGTGGAGAAAGACCATGGTTGTTGCTGAGAGGGTAAATATTCAATCATGGAGCATGACCCATATGGATGGCTA
AATATGCAAGTACTGAAGTAAGAGAAGACTAGAAATGCAGGATGAAATGTCAAAGGTCATTTTATTTACCTAGTCTCCTTAGAAATGGAG
TCCCCAACTACTCATTCAAAAGAAATCAGACATAAAATAAACAGACATCATATATGATATCCTTACTTGTGCCATGTTTTCCAAGACCAG
TGCATATTTTTAGACATCTCTTATTCGCCCAGCCATCTGCATGACATGGGTATTTATTAGTATTACCAGTTGGTGCTCAAAGTCAAACAA
AAATATTTTAGTTAATAATGGGCAGTAAAATATGATTTTACATTATTTTAAATATTTGGGAGAGTTAATTTGTTAGCTAAATAATTCAAG
GGAAAGAGATTATTCAACTGGTCATAATCACCCCTGATAATATTATTACTAATCTTAATTATTTATTACATCATCTCTTTCTCAATGGAT
CTAATGTTTTAATTTTTTCCCCTATTGGTAGAGAACAATAACAGAAGTAATTTTTATATTATACACTTGGAGAAATAAAGTTGAAACAGA
ATTAAAAATATTTCTCAAACAACTGTATCACAATATAAATTAAACTAATTCATTTTTGTGTAGACATACGAAATCACAAAAATAATAACA
CTGAAATAATTCTACCAATGCAGTGATGGAAACACTTTTCTTATGTACCAAGACATAGATAGGTAAGAGAAATAAAGAATTGAAGTGAAT
TAGAAAATCCATTTTATTGCTTGGGTTTAAAATAGTTGTGGGATACAAGTATTTACAATGCTATTGGAGTCAATTATTGACAACACTTTG
CAACAGTAATACCATTTCTAGCTTTTCAATTGGCAATACTTAGAACCTTACTGTAGTGACCTGATTTTAAATACCATATTATATTTACTA
AGTTAAGAGCTAGTTTTTACTCTCTTCCATAATTTCATTACATGAATGTAAGATGATGGCTCAAAAATGACGACTTATAGTTTGAATTTA
TGTGTATGCAATATACATATGAGAACCAAATTCAACAAGTGACATGAATGTTACTACATGAACATTGAATTGTATTGCCCTTGTCAGTTA

>6953_6953_2_ASAP1-CLVS1_ASAP1_chr8_131370263_ENST00000357668_CLVS1_chr8_62366700_ENST00000519846_length(amino acids)=206AA_BP=62
MRSSASRLSSFSSRDSLWNRMPDQISVSEFIAETTEDYNSPTTSSFTTRLHNCRNTVTLLEEDSFPARFGGVHFVNQPWYIHALYTLIKP
FLKDKTRKRIFLHGNNLNSLHQLIHPEFLPSEFGGTLPPYDMGTWARTLLGPDYSDENDYTHTSYNAMHVKHTSSNLERECSPKLMKRSQ

--------------------------------------------------------------
>6953_6953_3_ASAP1-CLVS1_ASAP1_chr8_131414130_ENST00000357668_CLVS1_chr8_62366699_ENST00000519846_length(transcript)=2607nt_BP=87nt
GGTCGTTTTCTGATGTGACGGCTGAGACATGAGATCTTCAGCCTCCAGGCTCTCCAGTTTTTCGTCGAGAGATTCACTATGGAATCGGAC
AGCTTTCCTGCCCGCTTTGGAGGAGTCCACTTTGTCAACCAGCCCTGGTACATTCATGCCCTCTACACACTCATCAAGCCATTTCTTAAA
GACAAGACCAGGAAACGGATTTTCCTGCATGGAAACAATTTAAACAGCCTTCACCAGCTAATACACCCTGAATTTTTGCCCTCTGAATTT
GGAGGAACTCTTCCTCCTTATGACATGGGAACTTGGGCCCGGACGTTACTCGGTCCCGACTACAGCGATGAAAATGACTATACTCACACA
TCCTATAATGCAATGCACGTGAAGCATACGTCCTCGAATCTGGAGAGAGAATGCTCACCCAAGCTGATGAAAAGATCTCAGTCTGTGGTA
GAAGCTGGGACCCTGAAACATGAGGAGAAGGGAGAGAATGAGAACACCCAGCCACTCCTGGCTCTGGACTGAACCCTGAGTCACCCCAAT
GCTCCTGCACACTGGCCTTCAGTGGTATCAGCCACCCAGGAAGCACATGCACAACTGACCCATGCAGACACGTGTGTTCTGCTTGACACA
AGGTCCTCCACTCCTGAACCCCTGCAGTGACTGTCACCAGCCATCGGTCTGAGCAGCCAAAGTTGGACAAAGACTTGAGAGATGCTTTTT
TTTTCCCCCAGTGAGGGGACTGGAGGATGATGCAAGGCATTTATGTAAAAAAGATTCTCCCTCCTTTCATATTTATTGTAGTAAATTGAA
AAAATAAAGACTAAATTTGATGGACACACTGCATTAGGACAAGAATTTTTCTGAGGTATCACACAGGGACCCTCTCCAGTTTTTGAAAAT
TAAGTGCATTTCCAAGTAAATGTATCAGAGTTAAACTGTACAGACACCACTGTCAAGTTTCATGTAGTACAAAGCCCTGAGACAATAGTA
TCTCCAGTAATTTCCATTCTTACTGAATTATTTCCTTTGACCTCATCACCAGCATCGAATTGTTCAGCCTAAGAGCATGTTCTCATAGGT
CTGGGTATTTGCAAAGTTTGCTTATTTTGATGATATCCTGCAAAAAATTATTTTGATGTCACATCTCTTGTCAGGTCACTAGCTGACTGT
CATGAGCTGACGTTAAAGGAAGACACATGGACGTGAAATACGATTATTTCATCTGAGCAATGTGAGTTACCACAGGCAGCTCAAAAGCCC
ATTAGTGCAGCATGTGTCTGCAGAGGAGATGTCTCATGAAAATCACATGTCAGTGATTAATGAATCCATTCCAGTTGCCTCAACTGGGTC
ACTACAGCAAAGAAAAGTGCTATCAAACCATTTACCCTTGCCCCCACAACCCTCCTGCAACCATTAAAGATGTGGAGAAAGACCATGGTT
GTTGCTGAGAGGGTAAATATTCAATCATGGAGCATGACCCATATGGATGGCTAAATATGCAAGTACTGAAGTAAGAGAAGACTAGAAATG
CAGGATGAAATGTCAAAGGTCATTTTATTTACCTAGTCTCCTTAGAAATGGAGTCCCCAACTACTCATTCAAAAGAAATCAGACATAAAA
TAAACAGACATCATATATGATATCCTTACTTGTGCCATGTTTTCCAAGACCAGTGCATATTTTTAGACATCTCTTATTCGCCCAGCCATC
TGCATGACATGGGTATTTATTAGTATTACCAGTTGGTGCTCAAAGTCAAACAAAAATATTTTAGTTAATAATGGGCAGTAAAATATGATT
TTACATTATTTTAAATATTTGGGAGAGTTAATTTGTTAGCTAAATAATTCAAGGGAAAGAGATTATTCAACTGGTCATAATCACCCCTGA
TAATATTATTACTAATCTTAATTATTTATTACATCATCTCTTTCTCAATGGATCTAATGTTTTAATTTTTTCCCCTATTGGTAGAGAACA
ATAACAGAAGTAATTTTTATATTATACACTTGGAGAAATAAAGTTGAAACAGAATTAAAAATATTTCTCAAACAACTGTATCACAATATA
AATTAAACTAATTCATTTTTGTGTAGACATACGAAATCACAAAAATAATAACACTGAAATAATTCTACCAATGCAGTGATGGAAACACTT
TTCTTATGTACCAAGACATAGATAGGTAAGAGAAATAAAGAATTGAAGTGAATTAGAAAATCCATTTTATTGCTTGGGTTTAAAATAGTT
GTGGGATACAAGTATTTACAATGCTATTGGAGTCAATTATTGACAACACTTTGCAACAGTAATACCATTTCTAGCTTTTCAATTGGCAAT
ACTTAGAACCTTACTGTAGTGACCTGATTTTAAATACCATATTATATTTACTAAGTTAAGAGCTAGTTTTTACTCTCTTCCATAATTTCA
TTACATGAATGTAAGATGATGGCTCAAAAATGACGACTTATAGTTTGAATTTATGTGTATGCAATATACATATGAGAACCAAATTCAACA

>6953_6953_3_ASAP1-CLVS1_ASAP1_chr8_131414130_ENST00000357668_CLVS1_chr8_62366699_ENST00000519846_length(amino acids)=166AA_BP=22
MRHEIFSLQALQFFVERFTMESDSFPARFGGVHFVNQPWYIHALYTLIKPFLKDKTRKRIFLHGNNLNSLHQLIHPEFLPSEFGGTLPPY

--------------------------------------------------------------
>6953_6953_4_ASAP1-CLVS1_ASAP1_chr8_131414130_ENST00000518721_CLVS1_chr8_62366699_ENST00000519846_length(transcript)=2807nt_BP=287nt
CCCTTCCTGCGCCGCGCTCGGCTCCCGCGCCTCGCCTGGCCTGGCCGCTGCCGCGGGCGAGCACTGTGCGCTGGGCAGCCCCGGGCCCGC
GCCTCCCGCCCAGCCGGCGCTTCCCGGTCGCAGTTCGCTTTCCCACCCGAGAGCCGCGAGCGCCCGGCCGAACCCGCGATGGAATAATGC
CCAGCGGCCCGCCAGGTCCCGGTCGTTTTCTGATGTGACGGCTGAGACATGAGATCTTCAGCCTCCAGGCTCTCCAGTTTTTCGTCGAGA
GATTCACTATGGAATCGGACAGCTTTCCTGCCCGCTTTGGAGGAGTCCACTTTGTCAACCAGCCCTGGTACATTCATGCCCTCTACACAC
TCATCAAGCCATTTCTTAAAGACAAGACCAGGAAACGGATTTTCCTGCATGGAAACAATTTAAACAGCCTTCACCAGCTAATACACCCTG
AATTTTTGCCCTCTGAATTTGGAGGAACTCTTCCTCCTTATGACATGGGAACTTGGGCCCGGACGTTACTCGGTCCCGACTACAGCGATG
AAAATGACTATACTCACACATCCTATAATGCAATGCACGTGAAGCATACGTCCTCGAATCTGGAGAGAGAATGCTCACCCAAGCTGATGA
AAAGATCTCAGTCTGTGGTAGAAGCTGGGACCCTGAAACATGAGGAGAAGGGAGAGAATGAGAACACCCAGCCACTCCTGGCTCTGGACT
GAACCCTGAGTCACCCCAATGCTCCTGCACACTGGCCTTCAGTGGTATCAGCCACCCAGGAAGCACATGCACAACTGACCCATGCAGACA
CGTGTGTTCTGCTTGACACAAGGTCCTCCACTCCTGAACCCCTGCAGTGACTGTCACCAGCCATCGGTCTGAGCAGCCAAAGTTGGACAA
AGACTTGAGAGATGCTTTTTTTTTCCCCCAGTGAGGGGACTGGAGGATGATGCAAGGCATTTATGTAAAAAAGATTCTCCCTCCTTTCAT
ATTTATTGTAGTAAATTGAAAAAATAAAGACTAAATTTGATGGACACACTGCATTAGGACAAGAATTTTTCTGAGGTATCACACAGGGAC
CCTCTCCAGTTTTTGAAAATTAAGTGCATTTCCAAGTAAATGTATCAGAGTTAAACTGTACAGACACCACTGTCAAGTTTCATGTAGTAC
AAAGCCCTGAGACAATAGTATCTCCAGTAATTTCCATTCTTACTGAATTATTTCCTTTGACCTCATCACCAGCATCGAATTGTTCAGCCT
AAGAGCATGTTCTCATAGGTCTGGGTATTTGCAAAGTTTGCTTATTTTGATGATATCCTGCAAAAAATTATTTTGATGTCACATCTCTTG
TCAGGTCACTAGCTGACTGTCATGAGCTGACGTTAAAGGAAGACACATGGACGTGAAATACGATTATTTCATCTGAGCAATGTGAGTTAC
CACAGGCAGCTCAAAAGCCCATTAGTGCAGCATGTGTCTGCAGAGGAGATGTCTCATGAAAATCACATGTCAGTGATTAATGAATCCATT
CCAGTTGCCTCAACTGGGTCACTACAGCAAAGAAAAGTGCTATCAAACCATTTACCCTTGCCCCCACAACCCTCCTGCAACCATTAAAGA
TGTGGAGAAAGACCATGGTTGTTGCTGAGAGGGTAAATATTCAATCATGGAGCATGACCCATATGGATGGCTAAATATGCAAGTACTGAA
GTAAGAGAAGACTAGAAATGCAGGATGAAATGTCAAAGGTCATTTTATTTACCTAGTCTCCTTAGAAATGGAGTCCCCAACTACTCATTC
AAAAGAAATCAGACATAAAATAAACAGACATCATATATGATATCCTTACTTGTGCCATGTTTTCCAAGACCAGTGCATATTTTTAGACAT
CTCTTATTCGCCCAGCCATCTGCATGACATGGGTATTTATTAGTATTACCAGTTGGTGCTCAAAGTCAAACAAAAATATTTTAGTTAATA
ATGGGCAGTAAAATATGATTTTACATTATTTTAAATATTTGGGAGAGTTAATTTGTTAGCTAAATAATTCAAGGGAAAGAGATTATTCAA
CTGGTCATAATCACCCCTGATAATATTATTACTAATCTTAATTATTTATTACATCATCTCTTTCTCAATGGATCTAATGTTTTAATTTTT
TCCCCTATTGGTAGAGAACAATAACAGAAGTAATTTTTATATTATACACTTGGAGAAATAAAGTTGAAACAGAATTAAAAATATTTCTCA
AACAACTGTATCACAATATAAATTAAACTAATTCATTTTTGTGTAGACATACGAAATCACAAAAATAATAACACTGAAATAATTCTACCA
ATGCAGTGATGGAAACACTTTTCTTATGTACCAAGACATAGATAGGTAAGAGAAATAAAGAATTGAAGTGAATTAGAAAATCCATTTTAT
TGCTTGGGTTTAAAATAGTTGTGGGATACAAGTATTTACAATGCTATTGGAGTCAATTATTGACAACACTTTGCAACAGTAATACCATTT
CTAGCTTTTCAATTGGCAATACTTAGAACCTTACTGTAGTGACCTGATTTTAAATACCATATTATATTTACTAAGTTAAGAGCTAGTTTT
TACTCTCTTCCATAATTTCATTACATGAATGTAAGATGATGGCTCAAAAATGACGACTTATAGTTTGAATTTATGTGTATGCAATATACA
TATGAGAACCAAATTCAACAAGTGACATGAATGTTACTACATGAACATTGAATTGTATTGCCCTTGTCAGTTATTTCCTCTGTTCAATAA

>6953_6953_4_ASAP1-CLVS1_ASAP1_chr8_131414130_ENST00000518721_CLVS1_chr8_62366699_ENST00000519846_length(amino acids)=194AA_BP=
MPCIILQSPHWGKKKASLKSLSNFGCSDRWLVTVTAGVQEWRTLCQAEHTCLHGSVVHVLPGWLIPLKASVQEHWGDSGFSPEPGVAGCS
HSLPSPHVSGSQLLPQTEIFSSAWVSILSPDSRTYASRALHYRMCEYSHFHRCSRDRVTSGPKFPCHKEEEFLQIQRAKIQGVLAGEGCL

--------------------------------------------------------------
>6953_6953_5_ASAP1-CLVS1_ASAP1_chr8_131414131_ENST00000357668_CLVS1_chr8_62366700_ENST00000519846_length(transcript)=2607nt_BP=87nt
GGTCGTTTTCTGATGTGACGGCTGAGACATGAGATCTTCAGCCTCCAGGCTCTCCAGTTTTTCGTCGAGAGATTCACTATGGAATCGGAC
AGCTTTCCTGCCCGCTTTGGAGGAGTCCACTTTGTCAACCAGCCCTGGTACATTCATGCCCTCTACACACTCATCAAGCCATTTCTTAAA
GACAAGACCAGGAAACGGATTTTCCTGCATGGAAACAATTTAAACAGCCTTCACCAGCTAATACACCCTGAATTTTTGCCCTCTGAATTT
GGAGGAACTCTTCCTCCTTATGACATGGGAACTTGGGCCCGGACGTTACTCGGTCCCGACTACAGCGATGAAAATGACTATACTCACACA
TCCTATAATGCAATGCACGTGAAGCATACGTCCTCGAATCTGGAGAGAGAATGCTCACCCAAGCTGATGAAAAGATCTCAGTCTGTGGTA
GAAGCTGGGACCCTGAAACATGAGGAGAAGGGAGAGAATGAGAACACCCAGCCACTCCTGGCTCTGGACTGAACCCTGAGTCACCCCAAT
GCTCCTGCACACTGGCCTTCAGTGGTATCAGCCACCCAGGAAGCACATGCACAACTGACCCATGCAGACACGTGTGTTCTGCTTGACACA
AGGTCCTCCACTCCTGAACCCCTGCAGTGACTGTCACCAGCCATCGGTCTGAGCAGCCAAAGTTGGACAAAGACTTGAGAGATGCTTTTT
TTTTCCCCCAGTGAGGGGACTGGAGGATGATGCAAGGCATTTATGTAAAAAAGATTCTCCCTCCTTTCATATTTATTGTAGTAAATTGAA
AAAATAAAGACTAAATTTGATGGACACACTGCATTAGGACAAGAATTTTTCTGAGGTATCACACAGGGACCCTCTCCAGTTTTTGAAAAT
TAAGTGCATTTCCAAGTAAATGTATCAGAGTTAAACTGTACAGACACCACTGTCAAGTTTCATGTAGTACAAAGCCCTGAGACAATAGTA
TCTCCAGTAATTTCCATTCTTACTGAATTATTTCCTTTGACCTCATCACCAGCATCGAATTGTTCAGCCTAAGAGCATGTTCTCATAGGT
CTGGGTATTTGCAAAGTTTGCTTATTTTGATGATATCCTGCAAAAAATTATTTTGATGTCACATCTCTTGTCAGGTCACTAGCTGACTGT
CATGAGCTGACGTTAAAGGAAGACACATGGACGTGAAATACGATTATTTCATCTGAGCAATGTGAGTTACCACAGGCAGCTCAAAAGCCC
ATTAGTGCAGCATGTGTCTGCAGAGGAGATGTCTCATGAAAATCACATGTCAGTGATTAATGAATCCATTCCAGTTGCCTCAACTGGGTC
ACTACAGCAAAGAAAAGTGCTATCAAACCATTTACCCTTGCCCCCACAACCCTCCTGCAACCATTAAAGATGTGGAGAAAGACCATGGTT
GTTGCTGAGAGGGTAAATATTCAATCATGGAGCATGACCCATATGGATGGCTAAATATGCAAGTACTGAAGTAAGAGAAGACTAGAAATG
CAGGATGAAATGTCAAAGGTCATTTTATTTACCTAGTCTCCTTAGAAATGGAGTCCCCAACTACTCATTCAAAAGAAATCAGACATAAAA
TAAACAGACATCATATATGATATCCTTACTTGTGCCATGTTTTCCAAGACCAGTGCATATTTTTAGACATCTCTTATTCGCCCAGCCATC
TGCATGACATGGGTATTTATTAGTATTACCAGTTGGTGCTCAAAGTCAAACAAAAATATTTTAGTTAATAATGGGCAGTAAAATATGATT
TTACATTATTTTAAATATTTGGGAGAGTTAATTTGTTAGCTAAATAATTCAAGGGAAAGAGATTATTCAACTGGTCATAATCACCCCTGA
TAATATTATTACTAATCTTAATTATTTATTACATCATCTCTTTCTCAATGGATCTAATGTTTTAATTTTTTCCCCTATTGGTAGAGAACA
ATAACAGAAGTAATTTTTATATTATACACTTGGAGAAATAAAGTTGAAACAGAATTAAAAATATTTCTCAAACAACTGTATCACAATATA
AATTAAACTAATTCATTTTTGTGTAGACATACGAAATCACAAAAATAATAACACTGAAATAATTCTACCAATGCAGTGATGGAAACACTT
TTCTTATGTACCAAGACATAGATAGGTAAGAGAAATAAAGAATTGAAGTGAATTAGAAAATCCATTTTATTGCTTGGGTTTAAAATAGTT
GTGGGATACAAGTATTTACAATGCTATTGGAGTCAATTATTGACAACACTTTGCAACAGTAATACCATTTCTAGCTTTTCAATTGGCAAT
ACTTAGAACCTTACTGTAGTGACCTGATTTTAAATACCATATTATATTTACTAAGTTAAGAGCTAGTTTTTACTCTCTTCCATAATTTCA
TTACATGAATGTAAGATGATGGCTCAAAAATGACGACTTATAGTTTGAATTTATGTGTATGCAATATACATATGAGAACCAAATTCAACA

>6953_6953_5_ASAP1-CLVS1_ASAP1_chr8_131414131_ENST00000357668_CLVS1_chr8_62366700_ENST00000519846_length(amino acids)=166AA_BP=22
MRHEIFSLQALQFFVERFTMESDSFPARFGGVHFVNQPWYIHALYTLIKPFLKDKTRKRIFLHGNNLNSLHQLIHPEFLPSEFGGTLPPY

--------------------------------------------------------------
>6953_6953_6_ASAP1-CLVS1_ASAP1_chr8_131414131_ENST00000518721_CLVS1_chr8_62366700_ENST00000519846_length(transcript)=2807nt_BP=287nt
CCCTTCCTGCGCCGCGCTCGGCTCCCGCGCCTCGCCTGGCCTGGCCGCTGCCGCGGGCGAGCACTGTGCGCTGGGCAGCCCCGGGCCCGC
GCCTCCCGCCCAGCCGGCGCTTCCCGGTCGCAGTTCGCTTTCCCACCCGAGAGCCGCGAGCGCCCGGCCGAACCCGCGATGGAATAATGC
CCAGCGGCCCGCCAGGTCCCGGTCGTTTTCTGATGTGACGGCTGAGACATGAGATCTTCAGCCTCCAGGCTCTCCAGTTTTTCGTCGAGA
GATTCACTATGGAATCGGACAGCTTTCCTGCCCGCTTTGGAGGAGTCCACTTTGTCAACCAGCCCTGGTACATTCATGCCCTCTACACAC
TCATCAAGCCATTTCTTAAAGACAAGACCAGGAAACGGATTTTCCTGCATGGAAACAATTTAAACAGCCTTCACCAGCTAATACACCCTG
AATTTTTGCCCTCTGAATTTGGAGGAACTCTTCCTCCTTATGACATGGGAACTTGGGCCCGGACGTTACTCGGTCCCGACTACAGCGATG
AAAATGACTATACTCACACATCCTATAATGCAATGCACGTGAAGCATACGTCCTCGAATCTGGAGAGAGAATGCTCACCCAAGCTGATGA
AAAGATCTCAGTCTGTGGTAGAAGCTGGGACCCTGAAACATGAGGAGAAGGGAGAGAATGAGAACACCCAGCCACTCCTGGCTCTGGACT
GAACCCTGAGTCACCCCAATGCTCCTGCACACTGGCCTTCAGTGGTATCAGCCACCCAGGAAGCACATGCACAACTGACCCATGCAGACA
CGTGTGTTCTGCTTGACACAAGGTCCTCCACTCCTGAACCCCTGCAGTGACTGTCACCAGCCATCGGTCTGAGCAGCCAAAGTTGGACAA
AGACTTGAGAGATGCTTTTTTTTTCCCCCAGTGAGGGGACTGGAGGATGATGCAAGGCATTTATGTAAAAAAGATTCTCCCTCCTTTCAT
ATTTATTGTAGTAAATTGAAAAAATAAAGACTAAATTTGATGGACACACTGCATTAGGACAAGAATTTTTCTGAGGTATCACACAGGGAC
CCTCTCCAGTTTTTGAAAATTAAGTGCATTTCCAAGTAAATGTATCAGAGTTAAACTGTACAGACACCACTGTCAAGTTTCATGTAGTAC
AAAGCCCTGAGACAATAGTATCTCCAGTAATTTCCATTCTTACTGAATTATTTCCTTTGACCTCATCACCAGCATCGAATTGTTCAGCCT
AAGAGCATGTTCTCATAGGTCTGGGTATTTGCAAAGTTTGCTTATTTTGATGATATCCTGCAAAAAATTATTTTGATGTCACATCTCTTG
TCAGGTCACTAGCTGACTGTCATGAGCTGACGTTAAAGGAAGACACATGGACGTGAAATACGATTATTTCATCTGAGCAATGTGAGTTAC
CACAGGCAGCTCAAAAGCCCATTAGTGCAGCATGTGTCTGCAGAGGAGATGTCTCATGAAAATCACATGTCAGTGATTAATGAATCCATT
CCAGTTGCCTCAACTGGGTCACTACAGCAAAGAAAAGTGCTATCAAACCATTTACCCTTGCCCCCACAACCCTCCTGCAACCATTAAAGA
TGTGGAGAAAGACCATGGTTGTTGCTGAGAGGGTAAATATTCAATCATGGAGCATGACCCATATGGATGGCTAAATATGCAAGTACTGAA
GTAAGAGAAGACTAGAAATGCAGGATGAAATGTCAAAGGTCATTTTATTTACCTAGTCTCCTTAGAAATGGAGTCCCCAACTACTCATTC
AAAAGAAATCAGACATAAAATAAACAGACATCATATATGATATCCTTACTTGTGCCATGTTTTCCAAGACCAGTGCATATTTTTAGACAT
CTCTTATTCGCCCAGCCATCTGCATGACATGGGTATTTATTAGTATTACCAGTTGGTGCTCAAAGTCAAACAAAAATATTTTAGTTAATA
ATGGGCAGTAAAATATGATTTTACATTATTTTAAATATTTGGGAGAGTTAATTTGTTAGCTAAATAATTCAAGGGAAAGAGATTATTCAA
CTGGTCATAATCACCCCTGATAATATTATTACTAATCTTAATTATTTATTACATCATCTCTTTCTCAATGGATCTAATGTTTTAATTTTT
TCCCCTATTGGTAGAGAACAATAACAGAAGTAATTTTTATATTATACACTTGGAGAAATAAAGTTGAAACAGAATTAAAAATATTTCTCA
AACAACTGTATCACAATATAAATTAAACTAATTCATTTTTGTGTAGACATACGAAATCACAAAAATAATAACACTGAAATAATTCTACCA
ATGCAGTGATGGAAACACTTTTCTTATGTACCAAGACATAGATAGGTAAGAGAAATAAAGAATTGAAGTGAATTAGAAAATCCATTTTAT
TGCTTGGGTTTAAAATAGTTGTGGGATACAAGTATTTACAATGCTATTGGAGTCAATTATTGACAACACTTTGCAACAGTAATACCATTT
CTAGCTTTTCAATTGGCAATACTTAGAACCTTACTGTAGTGACCTGATTTTAAATACCATATTATATTTACTAAGTTAAGAGCTAGTTTT
TACTCTCTTCCATAATTTCATTACATGAATGTAAGATGATGGCTCAAAAATGACGACTTATAGTTTGAATTTATGTGTATGCAATATACA
TATGAGAACCAAATTCAACAAGTGACATGAATGTTACTACATGAACATTGAATTGTATTGCCCTTGTCAGTTATTTCCTCTGTTCAATAA

>6953_6953_6_ASAP1-CLVS1_ASAP1_chr8_131414131_ENST00000518721_CLVS1_chr8_62366700_ENST00000519846_length(amino acids)=194AA_BP=
MPCIILQSPHWGKKKASLKSLSNFGCSDRWLVTVTAGVQEWRTLCQAEHTCLHGSVVHVLPGWLIPLKASVQEHWGDSGFSPEPGVAGCS
HSLPSPHVSGSQLLPQTEIFSSAWVSILSPDSRTYASRALHYRMCEYSHFHRCSRDRVTSGPKFPCHKEEEFLQIQRAKIQGVLAGEGCL

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Fusion Gene PPI Analysis for ASAP1-CLVS1


check button Go to ChiPPI (Chimeric Protein-Protein interactions) to see the chimeric PPI interaction in

ChiPPI page.


check button Protein-protein interactors with each fusion partner protein in wild-type (BIOGRID-3.4.160)
HgeneHgene's interactorsTgeneTgene's interactors


check button - Retained PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenStill interaction with


check button - Lost PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


check button - Retained PPIs, but lost function due to frame-shift fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


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Related Drugs for ASAP1-CLVS1


check button Drugs targeting genes involved in this fusion gene.
(DrugBank Version 5.1.8 2021-05-08)
PartnerGeneUniProtAccDrugBank IDDrug nameDrug activityDrug typeDrug status

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Related Diseases for ASAP1-CLVS1


check button Diseases associated with fusion partners.
(DisGeNet 4.0)
PartnerGeneDisease IDDisease name# pubmedsSource