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 | Fusion Gene Summary |
| Fusion Gene ORF analysis |
| Fusion Genomic Features |
| Fusion Protein Features |
| Fusion Gene Sequence |
| Fusion Gene PPI analysis |
| Related Drugs |
| Related Diseases |
Fusion gene:PSMG2-PTPN2 (FusionGDB2 ID:69766) |
Fusion Gene Summary for PSMG2-PTPN2 |
 Fusion gene summary |
| Fusion gene information | Fusion gene name: PSMG2-PTPN2 | Fusion gene ID: 69766 | Hgene | Tgene | Gene symbol | PSMG2 | PTPN2 | Gene ID | 56984 | 5771 |
| Gene name | proteasome assembly chaperone 2 | protein tyrosine phosphatase non-receptor type 2 | |
| Synonyms | CLAST3|HCCA3|HsT1707|MDS003|PAC2|TNFSF5IP1 | PTN2|PTPT|TC-PTP|TCELLPTP|TCPTP | |
| Cytomap | 18p11.21 | 18p11.21 | |
| Type of gene | protein-coding | protein-coding | |
| Description | proteasome assembly chaperone 2CD40 ligand-activated specific transcript 3HDCMC29PHSPC260PAC-2hepatocellular carcinoma susceptibility proteinhepatocellular carcinoma-susceptibility protein 3likely ortholog of mouse CD40 ligand-activated specific tr | tyrosine-protein phosphatase non-receptor type 2T-cell protein tyrosine phosphatase | |
| Modification date | 20200313 | 20200329 | |
| UniProtAcc | . | . | |
| Ensembl transtripts involved in fusion gene | ENST00000317615, ENST00000585331, ENST00000590217, ENST00000589405, | ENST00000589086, ENST00000591497, ENST00000309660, ENST00000327283, ENST00000353319, ENST00000591115, | |
| Fusion gene scores | * DoF score | 4 X 4 X 4=64 | 8 X 9 X 5=360 |
| # samples | 5 | 9 | |
| ** MAII score | log2(5/64*10)=-0.356143810225275 possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs). DoF>8 and MAII<0 | log2(9/360*10)=-2 possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs). DoF>8 and MAII<0 | |
| Context | PubMed: PSMG2 [Title/Abstract] AND PTPN2 [Title/Abstract] AND fusion [Title/Abstract] | ||
| Most frequent breakpoint | PSMG2(12724618)-PTPN2(12825943), # samples:2 | ||
| Anticipated loss of major functional domain due to fusion event. | |||
| * DoF score (Degree of Frequency) = # partners X # break points X # cancer types ** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10) |
| Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez |
| Partner | Gene | GO ID | GO term | PubMed ID |
| Hgene | PSMG2 | GO:0043248 | proteasome assembly | 16251969 |
| Fusion gene breakpoints across PSMG2 (5'-gene) * Click on the image to open the UCSC genome browser with custom track showing this image in a new window. |
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| Fusion gene breakpoints across PTPN2 (3'-gene) * Click on the image to open the UCSC genome browser with custom track showing this image in a new window. |
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| Fusion gene information from two resources (ChiTars 5.0 and ChimerDB 4.0) * All genome coordinats were lifted-over on hg19. * Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser. |
| Source | Disease | Sample | Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand |
| ChimerDB4 | LUSC | TCGA-68-8251-01A | PSMG2 | chr18 | 12724618 | + | PTPN2 | chr18 | 12825943 | - |
| ChimerDB4 | LUSC | TCGA-68-8251 | PSMG2 | chr18 | 12724618 | + | PTPN2 | chr18 | 12825943 | - |
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Fusion Gene ORF analysis for PSMG2-PTPN2 |
| Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure. * Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser. |
| ORF | Henst | Tenst | Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand |
| 5CDS-intron | ENST00000317615 | ENST00000589086 | PSMG2 | chr18 | 12724618 | + | PTPN2 | chr18 | 12825943 | - |
| 5CDS-intron | ENST00000317615 | ENST00000591497 | PSMG2 | chr18 | 12724618 | + | PTPN2 | chr18 | 12825943 | - |
| 5CDS-intron | ENST00000585331 | ENST00000589086 | PSMG2 | chr18 | 12724618 | + | PTPN2 | chr18 | 12825943 | - |
| 5CDS-intron | ENST00000585331 | ENST00000591497 | PSMG2 | chr18 | 12724618 | + | PTPN2 | chr18 | 12825943 | - |
| 5CDS-intron | ENST00000590217 | ENST00000589086 | PSMG2 | chr18 | 12724618 | + | PTPN2 | chr18 | 12825943 | - |
| 5CDS-intron | ENST00000590217 | ENST00000591497 | PSMG2 | chr18 | 12724618 | + | PTPN2 | chr18 | 12825943 | - |
| In-frame | ENST00000317615 | ENST00000309660 | PSMG2 | chr18 | 12724618 | + | PTPN2 | chr18 | 12825943 | - |
| In-frame | ENST00000317615 | ENST00000327283 | PSMG2 | chr18 | 12724618 | + | PTPN2 | chr18 | 12825943 | - |
| In-frame | ENST00000317615 | ENST00000353319 | PSMG2 | chr18 | 12724618 | + | PTPN2 | chr18 | 12825943 | - |
| In-frame | ENST00000317615 | ENST00000591115 | PSMG2 | chr18 | 12724618 | + | PTPN2 | chr18 | 12825943 | - |
| In-frame | ENST00000585331 | ENST00000309660 | PSMG2 | chr18 | 12724618 | + | PTPN2 | chr18 | 12825943 | - |
| In-frame | ENST00000585331 | ENST00000327283 | PSMG2 | chr18 | 12724618 | + | PTPN2 | chr18 | 12825943 | - |
| In-frame | ENST00000585331 | ENST00000353319 | PSMG2 | chr18 | 12724618 | + | PTPN2 | chr18 | 12825943 | - |
| In-frame | ENST00000585331 | ENST00000591115 | PSMG2 | chr18 | 12724618 | + | PTPN2 | chr18 | 12825943 | - |
| In-frame | ENST00000590217 | ENST00000309660 | PSMG2 | chr18 | 12724618 | + | PTPN2 | chr18 | 12825943 | - |
| In-frame | ENST00000590217 | ENST00000327283 | PSMG2 | chr18 | 12724618 | + | PTPN2 | chr18 | 12825943 | - |
| In-frame | ENST00000590217 | ENST00000353319 | PSMG2 | chr18 | 12724618 | + | PTPN2 | chr18 | 12825943 | - |
| In-frame | ENST00000590217 | ENST00000591115 | PSMG2 | chr18 | 12724618 | + | PTPN2 | chr18 | 12825943 | - |
| intron-3CDS | ENST00000589405 | ENST00000309660 | PSMG2 | chr18 | 12724618 | + | PTPN2 | chr18 | 12825943 | - |
| intron-3CDS | ENST00000589405 | ENST00000327283 | PSMG2 | chr18 | 12724618 | + | PTPN2 | chr18 | 12825943 | - |
| intron-3CDS | ENST00000589405 | ENST00000353319 | PSMG2 | chr18 | 12724618 | + | PTPN2 | chr18 | 12825943 | - |
| intron-3CDS | ENST00000589405 | ENST00000591115 | PSMG2 | chr18 | 12724618 | + | PTPN2 | chr18 | 12825943 | - |
| intron-intron | ENST00000589405 | ENST00000589086 | PSMG2 | chr18 | 12724618 | + | PTPN2 | chr18 | 12825943 | - |
| intron-intron | ENST00000589405 | ENST00000591497 | PSMG2 | chr18 | 12724618 | + | PTPN2 | chr18 | 12825943 | - |
| ORFfinder result based on the fusion transcript sequence of in-frame fusion genes. |
| Henst | Tenst | Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand | Seq length (transcript) | BP loci (transcript) | Predicted start (transcript) | Predicted stop (transcript) | Seq length (amino acids) |
| ENST00000585331 | PSMG2 | chr18 | 12724618 | + | ENST00000327283 | PTPN2 | chr18 | 12825943 | - | 1830 | 681 | 3 | 1484 | 493 |
| ENST00000585331 | PSMG2 | chr18 | 12724618 | + | ENST00000591115 | PTPN2 | chr18 | 12825943 | - | 1896 | 681 | 3 | 1553 | 516 |
| ENST00000585331 | PSMG2 | chr18 | 12724618 | + | ENST00000353319 | PTPN2 | chr18 | 12825943 | - | 1723 | 681 | 3 | 1382 | 459 |
| ENST00000585331 | PSMG2 | chr18 | 12724618 | + | ENST00000309660 | PTPN2 | chr18 | 12825943 | - | 3694 | 681 | 3 | 1568 | 521 |
| ENST00000317615 | PSMG2 | chr18 | 12724618 | + | ENST00000327283 | PTPN2 | chr18 | 12825943 | - | 2533 | 1384 | 376 | 2187 | 603 |
| ENST00000317615 | PSMG2 | chr18 | 12724618 | + | ENST00000591115 | PTPN2 | chr18 | 12825943 | - | 2599 | 1384 | 376 | 2256 | 626 |
| ENST00000317615 | PSMG2 | chr18 | 12724618 | + | ENST00000353319 | PTPN2 | chr18 | 12825943 | - | 2426 | 1384 | 376 | 2085 | 569 |
| ENST00000317615 | PSMG2 | chr18 | 12724618 | + | ENST00000309660 | PTPN2 | chr18 | 12825943 | - | 4397 | 1384 | 376 | 2271 | 631 |
| ENST00000590217 | PSMG2 | chr18 | 12724618 | + | ENST00000327283 | PTPN2 | chr18 | 12825943 | - | 2064 | 915 | 813 | 1718 | 301 |
| ENST00000590217 | PSMG2 | chr18 | 12724618 | + | ENST00000591115 | PTPN2 | chr18 | 12825943 | - | 2130 | 915 | 813 | 1787 | 324 |
| ENST00000590217 | PSMG2 | chr18 | 12724618 | + | ENST00000353319 | PTPN2 | chr18 | 12825943 | - | 1957 | 915 | 813 | 1616 | 267 |
| ENST00000590217 | PSMG2 | chr18 | 12724618 | + | ENST00000309660 | PTPN2 | chr18 | 12825943 | - | 3928 | 915 | 813 | 1802 | 329 |
| DeepORF prediction of the coding potential based on the fusion transcript sequence of in-frame fusion genes. DeepORF is a coding potential classifier based on convolutional neural network by comparing the real Ribo-seq data. If the no-coding score < 0.5 and coding score > 0.5, then the in-frame fusion transcript is predicted as being likely translated. |
| Henst | Tenst | Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand | No-coding score | Coding score |
| ENST00000585331 | ENST00000327283 | PSMG2 | chr18 | 12724618 | + | PTPN2 | chr18 | 12825943 | - | 0.000557025 | 0.999443 |
| ENST00000585331 | ENST00000591115 | PSMG2 | chr18 | 12724618 | + | PTPN2 | chr18 | 12825943 | - | 0.000532417 | 0.99946755 |
| ENST00000585331 | ENST00000353319 | PSMG2 | chr18 | 12724618 | + | PTPN2 | chr18 | 12825943 | - | 0.000444929 | 0.99955505 |
| ENST00000585331 | ENST00000309660 | PSMG2 | chr18 | 12724618 | + | PTPN2 | chr18 | 12825943 | - | 0.000305145 | 0.9996948 |
| ENST00000317615 | ENST00000327283 | PSMG2 | chr18 | 12724618 | + | PTPN2 | chr18 | 12825943 | - | 0.000942488 | 0.9990575 |
| ENST00000317615 | ENST00000591115 | PSMG2 | chr18 | 12724618 | + | PTPN2 | chr18 | 12825943 | - | 0.001109841 | 0.9988902 |
| ENST00000317615 | ENST00000353319 | PSMG2 | chr18 | 12724618 | + | PTPN2 | chr18 | 12825943 | - | 0.000924212 | 0.9990758 |
| ENST00000317615 | ENST00000309660 | PSMG2 | chr18 | 12724618 | + | PTPN2 | chr18 | 12825943 | - | 0.000381764 | 0.9996182 |
| ENST00000590217 | ENST00000327283 | PSMG2 | chr18 | 12724618 | + | PTPN2 | chr18 | 12825943 | - | 0.001504628 | 0.99849534 |
| ENST00000590217 | ENST00000591115 | PSMG2 | chr18 | 12724618 | + | PTPN2 | chr18 | 12825943 | - | 0.001006138 | 0.9989938 |
| ENST00000590217 | ENST00000353319 | PSMG2 | chr18 | 12724618 | + | PTPN2 | chr18 | 12825943 | - | 0.001075794 | 0.9989242 |
| ENST00000590217 | ENST00000309660 | PSMG2 | chr18 | 12724618 | + | PTPN2 | chr18 | 12825943 | - | 0.000913564 | 0.9990864 |
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Fusion Genomic Features for PSMG2-PTPN2 |
| FusionAI prediction of the potential fusion gene breakpoint based on the pre-mature RNA sequence context (+/- 5kb of individual partner genes, total 20kb length sequence). FusionAI is a fusion gene breakpoint classifier based on convolutional neural network by comparing the fusion positive and negative sequence context of ~ 20K fusion gene data. From here, we can have the relative potentency of the 20K genomic sequence how individual sequnce will be likely used as the gene fusion breakpoints. |
| Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand | 1-p | p (fusion gene breakpoint) |
| Distribution of 44 human genomic features loci across 20kb length fusion breakpoint regions. We integrated a total of 44 different types of human genomic feature loci information across five big categories including virus integration sites, repeats, structural variants, chromatin states, and gene expression regulation. More details are in help page. |
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| Distribution of 44 human genomic features loci across 20kb length fusion breakpoint regions that are ovelapped with the top 1% feature importance score regions. More details are in help page. |
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Fusion Protein Features for PSMG2-PTPN2 |
| Four levels of functional features of fusion genes Go to FGviewer search page for the most frequent breakpoint (https://ccsmweb.uth.edu/FGviewer/chr18:12724618/chr18:12825943) - FGviewer provides the online visualization of the retention search of the protein functional features across DNA, RNA, protein, and pathological levels. - How to search 1. Put your fusion gene symbol. 2. Press the tab key until there will be shown the breakpoint information filled. 4. Go down and press 'Search' tab twice. 4. Go down to have the hyperlink of the search result. 5. Click the hyperlink. 6. See the FGviewer result for your fusion gene. |
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| Main function of each fusion partner protein. (from UniProt) |
| Hgene | Tgene |
| . | . |
| FUNCTION: Transcriptional activator which is required for calcium-dependent dendritic growth and branching in cortical neurons. Recruits CREB-binding protein (CREBBP) to nuclear bodies. Component of the CREST-BRG1 complex, a multiprotein complex that regulates promoter activation by orchestrating a calcium-dependent release of a repressor complex and a recruitment of an activator complex. In resting neurons, transcription of the c-FOS promoter is inhibited by BRG1-dependent recruitment of a phospho-RB1-HDAC1 repressor complex. Upon calcium influx, RB1 is dephosphorylated by calcineurin, which leads to release of the repressor complex. At the same time, there is increased recruitment of CREBBP to the promoter by a CREST-dependent mechanism, which leads to transcriptional activation. The CREST-BRG1 complex also binds to the NR2B promoter, and activity-dependent induction of NR2B expression involves a release of HDAC1 and recruitment of CREBBP (By similarity). {ECO:0000250}. | FUNCTION: Transcriptional activator which is required for calcium-dependent dendritic growth and branching in cortical neurons. Recruits CREB-binding protein (CREBBP) to nuclear bodies. Component of the CREST-BRG1 complex, a multiprotein complex that regulates promoter activation by orchestrating a calcium-dependent release of a repressor complex and a recruitment of an activator complex. In resting neurons, transcription of the c-FOS promoter is inhibited by BRG1-dependent recruitment of a phospho-RB1-HDAC1 repressor complex. Upon calcium influx, RB1 is dephosphorylated by calcineurin, which leads to release of the repressor complex. At the same time, there is increased recruitment of CREBBP to the promoter by a CREST-dependent mechanism, which leads to transcriptional activation. The CREST-BRG1 complex also binds to the NR2B promoter, and activity-dependent induction of NR2B expression involves a release of HDAC1 and recruitment of CREBBP (By similarity). {ECO:0000250}. |
| Retention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at * Minus value of BPloci means that the break pointn is located before the CDS. |
| - In-frame and retained protein feature among the 13 regional features. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Protein feature | Protein feature note |
| Tgene | PTPN2 | chr18:12724618 | chr18:12825943 | ENST00000309660 | 3 | 9 | 216_222 | 120 | 416.0 | Region | Substrate binding | |
| Tgene | PTPN2 | chr18:12724618 | chr18:12825943 | ENST00000309660 | 3 | 9 | 346_415 | 120 | 416.0 | Region | Note=Endoplasmic reticulum location | |
| Tgene | PTPN2 | chr18:12724618 | chr18:12825943 | ENST00000327283 | 3 | 10 | 216_222 | 120 | 388.0 | Region | Substrate binding | |
| Tgene | PTPN2 | chr18:12724618 | chr18:12825943 | ENST00000327283 | 3 | 10 | 346_415 | 120 | 388.0 | Region | Note=Endoplasmic reticulum location | |
| Tgene | PTPN2 | chr18:12724618 | chr18:12825943 | ENST00000353319 | 3 | 9 | 216_222 | 120 | 354.0 | Region | Substrate binding | |
| Tgene | PTPN2 | chr18:12724618 | chr18:12825943 | ENST00000353319 | 3 | 9 | 346_415 | 120 | 354.0 | Region | Note=Endoplasmic reticulum location |
| - In-frame and not-retained protein feature among the 13 regional features. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Protein feature | Protein feature note |
| Tgene | PTPN2 | chr18:12724618 | chr18:12825943 | ENST00000309660 | 3 | 9 | 5_275 | 120 | 416.0 | Domain | Tyrosine-protein phosphatase | |
| Tgene | PTPN2 | chr18:12724618 | chr18:12825943 | ENST00000327283 | 3 | 10 | 5_275 | 120 | 388.0 | Domain | Tyrosine-protein phosphatase | |
| Tgene | PTPN2 | chr18:12724618 | chr18:12825943 | ENST00000353319 | 3 | 9 | 5_275 | 120 | 354.0 | Domain | Tyrosine-protein phosphatase |
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Fusion Gene Sequence for PSMG2-PTPN2 |
| For in-frame fusion transcripts, we provide the fusion transcript sequences and fusion amino acid sequences. To have fusion amino acid sequence, we ran ORFfinder and chose the longest ORF among the all predicted ones. |
| >69766_69766_1_PSMG2-PTPN2_PSMG2_chr18_12724618_ENST00000317615_PTPN2_chr18_12825943_ENST00000309660_length(transcript)=4397nt_BP=1384nt GGCAGGAGGGAAAGGTTATGGGTCGGCCCGGCGGTCTCTCCCAGCACCCGCGACTCTCACCTTGCTCAGCTGCTGGTGGATGAGCTGCTT CAGCTCGGAGGCTTTCTCCGGAGGCAGCGACATGCTGGCAGCCGGCGTCTCCCCGCCGCTTCTCCCCGCCTCAGATGCCCTAACTGCGCG GCCCCGGCCGGGCCAGGGAGCGTTAGGAGCGACTGGAGCACAAAGCGCCGCAGCCGTTCGCCTAGCGCAGCTCCCGGGGGACGCAACGCC GCGTCAGGCCGGGGGCTGACCTGGAAATGAGGCCCCGGCGGCGGCGGCGCCAACTGTTTTCAAACAGTGGCGGACAAACAGGGCTTGGGG CTGGCCCGCACGCTGCCTGATCGTTTCCGCCCGCCGCTCCACCTCCCCGCGGGCCCCGCACCCCGAGACCTCAGCGCACCCCATCGCCTT GCTTGCCAGGGTCTCCGAAAGCGCTGCTGGCCCCTCTTCGCGGCCACCCGGCGGCCTCTTTCCGCCCTCTGAACCGGCAGTTAGCTGGAC GGGCCTCAAGGGCCCGGCGCCCAGGGACTCAAAGGACCCTCCCGCGCCCCGCGAGGCTCCGGGGTCTCGGGCTTCCGCCTTCTTGCTGCC CTCGTTCTTGCCAGGGCCGCGGTTAGTCCCTGCTGGCCACCCCACTGCGACCATGTTCGTTCCCTGCGGGGAGTCGGCCCCCGACCTTGC CGGCTTCACCCTCCTAATGCCAGCAGTATCTGTTGGAAATGTTGGCCAGCTTGCAATGGATCTGATTATTTCTACACTGAATATGTCTAA GATTGGTTACTTCTATACCGATTGTCTTGTGCCAATGGTTGGAAACAATCCATATGCGACCACAGAAGGAAATTCAACAGAACTTAGCAT AAATGCTGAAGTGTATTCATTGCCTTCAAGAAAGCTGGTGGCTCTACAGTTAAGATCCATTTTTATTAAGTATAAATCAAAGCCATTCTG TGAAAAACTGCTTTCCTGGGTGAAAAGCAGTGGCTGTGCCAGAGTCATTGTTCTTTCAAGCAGTCATTCATATCAGCGTAATGATCTGCA GCTTCGTAGTACTCCCTTCCGGTACCTACTTACACCTTCCATGCAAAAAAGTGTTCAAAATAAAATAAAGAGCCTTAACTGGGAAGAAAT GGAAAAAAGCCGGTGCATTCCTGAAATAGATGATTCCGAGTTTTGTATCCGCATTCCGGGAGGAGGTATCACAAAAACACTCTATGATGA AAGCTGTTCTAAAGAAATCCAAATGGCAGTTCTGCTGAAATTTGTTTCAGAAGGGGACAACATCCCAGATGCATTAGGTCTTGTTGAGTA TCTTAATGAGTGGCTTCAGATACTCAAACCACTTGTTAAATGTGCACAGTACTGGCCAACAGATGACCAAGAGATGCTGTTTAAAGAAAC AGGATTCAGTGTGAAGCTCTTGTCAGAAGATGTGAAGTCGTATTATACAGTACATCTACTACAATTAGAAAATATCAATAGTGGTGAAAC CAGAACAATATCTCACTTTCATTATACTACCTGGCCAGATTTTGGAGTCCCTGAATCACCAGCTTCATTTCTCAATTTCTTGTTTAAAGT GAGAGAATCTGGCTCCTTGAACCCTGACCATGGGCCTGCGGTGATCCACTGTAGTGCAGGCATTGGGCGCTCTGGCACCTTCTCTCTGGT AGACACTTGTCTTGTTTTGATGGAAAAAGGAGATGATATTAACATAAAACAAGTGTTACTGAACATGAGAAAATACCGAATGGGTCTTAT TCAGACCCCAGATCAACTGAGATTCTCATACATGGCTATAATAGAAGGAGCAAAATGTATAAAGGGAGATTCTAGTATACAGAAACGATG GAAAGAACTTTCTAAGGAAGACTTATCTCCTGCCTTTGATCATTCACCAAACAAAATAATGACTGAAAAATACAATGGGAACAGAATAGG TCTAGAAGAAGAAAAACTGACAGGTGACCGATGTACAGGACTTTCCTCTAAAATGCAAGATACAATGGAGGAGAACAGTGAGAGTGCTCT ACGGAAACGTATTCGAGAGGACAGAAAGGCCACCACAGCTCAGAAGGTGCAGCAGATGAAACAGAGGCTAAATGAGAATGAACGAAAAAG AAAAAGGTGGTTATATTGGCAACCTATTCTCACTAAGATGGGGTTTATGTCAGTCATTTTGGTTGGCGCTTTTGTTGGCTGGACACTGTT TTTTCAGCAAAATGCCCTATAAACAATTAATTTTGCCCAGCAAGCTTCTGCACTAGTAACTGACAGTGCTACATTAATCATAGGGGTTTG TCTGCAGCAAACGCCTCATATCCCAAAAACGGTGCAGTAGAATAGACATCAACCAGATAAGTGATATTTACAGTCACAAGCCCAACATCT CAGGACTCTTGACTGCAGGTTCCTCTGAACCCCAAACTGTAAATGGCTGTCTAAAATAAAGACATTCATGTTTGTTAAAAACTGGTAAAT TTTGCAACTGTATTCATACATGTCAAACACAGTATTTCACCTGACCAACATTGAGATATCCTTTATCACAGGATTTGTTTTTGGAGGCTA TCTGGATTTTAACCTGCACTTGATATAAGCAATAAATATTGTGGTTTTATCTACGTTATTGGAAAGAAAATGACATTTAAATAATGTGTG TAATGTATAATGTACTATTGACATGGGCATCAACACTTTTATTCTTAAGCATTTCAGGGTAAATATATTTTATAAGTATCTATTTAATCT TTTGTAGTTAACTGTACTTTTTAAGAGCTCAATTTGAAAAATCTGTTACTAAAAAAATAAATTGTATGTCGATTGAATTGTACTGGATAC ATTTTCCATTTTTCTAAAGAGAAGTTTGATATGAGCAGTTAGAAGTTGGAATAAGCAATTTCTACTATATATTGCATTTCTTTTATGTTT TACAGTTTTCCCCATTTTAAAAAGAAAAGCAAACAAAGAAACAAAAGTTTTTCCTAAAAATATCTTTGAAGGAAAATTCTCCTTACTGGG ATAGTCAGGTAAACAGTTGGTCAAGACTTTGTAAAGAAATTGGTTTCTGTAAATCCCATTATTGATATGTTTATTTTTCATGAAAATTTC AATGTAGTTGGGGTAGATTATGATTTAGGAAGCAAAAGTAAGAAGCAGCATTTTATGATTCATAATTTCAGTTTACTAGACTGAAGTTTT GAAGTAAACACTTTTCAGTTTCTTTCTACTTCAATAAATAGTATGATTATATGCAAACCTTACATTGTCATTTTAACTTAATGAATATTT TTTAAAGCAAACTGTTTAATGAATTTAACTGCTCATTTGAATGCTAGCTTTCCTCAGATTTCAACATTCCATTCAGTGTTTAATTTGTCT TACTTAAACTTGAAATTGTTGTTACAAATTTAATTGCTAGGAGGCATGGATAGCATACATTATTATGGATAGCATACCTTATTTCAGTGG TTTTCAAACTATGCTCATTGGATGTCCAGGTGGGTCAAGAGGTTACTTTCAACCACAGCATCTCTGCCTTGTCTCTTTATATGCCACATA AGATTTCTGCATAAGGCTTAAGTATTTTAAAGGGGGCAGTTATCATTTAAAAACAGTTTGGTCGGGCGCGGTGGCTCATGCCTGTAATCC CAGCACTTTGGGAGGCTGAAGTGGGCAGATCACCTGAGGTCAGGAGTTCAAGACCAGCCTGGCCAACGTGGTGAAACACCATCTCTACTA AAAATGCAAAAATTAGCTGGGCATGGTGGAGGGCACCTGTAATCTCAGCTACTCAGGAGGCTGAGGTAGGAGAATTGCTTGAACCCAGGA GATGGAGGTTGCAGTGAGCTGAGATCACGTCACTGCACTCCAGCCAGGGCGACAGAGCGAGACTCCATCTCAAAAGAAACAAACAAAAAA AACAGTTTGGGCCGGGTGTGGTGGCTCACGCTTGTAATCCCAGCACTTCGGAAGGCCAAGGCGGGCGGATCACGAGGTCAAGAGATGGAG ACTGTCCTGGCCAACATGGTGAAATCCCTTCTTTACTAAAAATACAAAAATTATCTGGGCGTGGTGGTGCATGCCTGTAGTCCCAGCTCC TTGGGAGGCTAAGGCAGGAGAATCACTTGAACCCGGGAGGCAGAGGTTGCAGTGAGCCGAGATTGCACCACTGCACTCCAGCCTGGCAAC AGAGCAAGACTTCGTCTCAAAAAAAAAAAAAAAAAAAGTTTGAAAACCATTGGTATAGATAGATATTTTGAATTGATTTGCATAGTCTCC >69766_69766_1_PSMG2-PTPN2_PSMG2_chr18_12724618_ENST00000317615_PTPN2_chr18_12825943_ENST00000309660_length(amino acids)=631AA_BP=336 MIVSARRSTSPRAPHPETSAHPIALLARVSESAAGPSSRPPGGLFPPSEPAVSWTGLKGPAPRDSKDPPAPREAPGSRASAFLLPSFLPG PRLVPAGHPTATMFVPCGESAPDLAGFTLLMPAVSVGNVGQLAMDLIISTLNMSKIGYFYTDCLVPMVGNNPYATTEGNSTELSINAEVY SLPSRKLVALQLRSIFIKYKSKPFCEKLLSWVKSSGCARVIVLSSSHSYQRNDLQLRSTPFRYLLTPSMQKSVQNKIKSLNWEEMEKSRC IPEIDDSEFCIRIPGGGITKTLYDESCSKEIQMAVLLKFVSEGDNIPDALGLVEYLNEWLQILKPLVKCAQYWPTDDQEMLFKETGFSVK LLSEDVKSYYTVHLLQLENINSGETRTISHFHYTTWPDFGVPESPASFLNFLFKVRESGSLNPDHGPAVIHCSAGIGRSGTFSLVDTCLV LMEKGDDINIKQVLLNMRKYRMGLIQTPDQLRFSYMAIIEGAKCIKGDSSIQKRWKELSKEDLSPAFDHSPNKIMTEKYNGNRIGLEEEK LTGDRCTGLSSKMQDTMEENSESALRKRIREDRKATTAQKVQQMKQRLNENERKRKRWLYWQPILTKMGFMSVILVGAFVGWTLFFQQNA -------------------------------------------------------------- >69766_69766_2_PSMG2-PTPN2_PSMG2_chr18_12724618_ENST00000317615_PTPN2_chr18_12825943_ENST00000327283_length(transcript)=2533nt_BP=1384nt GGCAGGAGGGAAAGGTTATGGGTCGGCCCGGCGGTCTCTCCCAGCACCCGCGACTCTCACCTTGCTCAGCTGCTGGTGGATGAGCTGCTT CAGCTCGGAGGCTTTCTCCGGAGGCAGCGACATGCTGGCAGCCGGCGTCTCCCCGCCGCTTCTCCCCGCCTCAGATGCCCTAACTGCGCG GCCCCGGCCGGGCCAGGGAGCGTTAGGAGCGACTGGAGCACAAAGCGCCGCAGCCGTTCGCCTAGCGCAGCTCCCGGGGGACGCAACGCC GCGTCAGGCCGGGGGCTGACCTGGAAATGAGGCCCCGGCGGCGGCGGCGCCAACTGTTTTCAAACAGTGGCGGACAAACAGGGCTTGGGG CTGGCCCGCACGCTGCCTGATCGTTTCCGCCCGCCGCTCCACCTCCCCGCGGGCCCCGCACCCCGAGACCTCAGCGCACCCCATCGCCTT GCTTGCCAGGGTCTCCGAAAGCGCTGCTGGCCCCTCTTCGCGGCCACCCGGCGGCCTCTTTCCGCCCTCTGAACCGGCAGTTAGCTGGAC GGGCCTCAAGGGCCCGGCGCCCAGGGACTCAAAGGACCCTCCCGCGCCCCGCGAGGCTCCGGGGTCTCGGGCTTCCGCCTTCTTGCTGCC CTCGTTCTTGCCAGGGCCGCGGTTAGTCCCTGCTGGCCACCCCACTGCGACCATGTTCGTTCCCTGCGGGGAGTCGGCCCCCGACCTTGC CGGCTTCACCCTCCTAATGCCAGCAGTATCTGTTGGAAATGTTGGCCAGCTTGCAATGGATCTGATTATTTCTACACTGAATATGTCTAA GATTGGTTACTTCTATACCGATTGTCTTGTGCCAATGGTTGGAAACAATCCATATGCGACCACAGAAGGAAATTCAACAGAACTTAGCAT AAATGCTGAAGTGTATTCATTGCCTTCAAGAAAGCTGGTGGCTCTACAGTTAAGATCCATTTTTATTAAGTATAAATCAAAGCCATTCTG TGAAAAACTGCTTTCCTGGGTGAAAAGCAGTGGCTGTGCCAGAGTCATTGTTCTTTCAAGCAGTCATTCATATCAGCGTAATGATCTGCA GCTTCGTAGTACTCCCTTCCGGTACCTACTTACACCTTCCATGCAAAAAAGTGTTCAAAATAAAATAAAGAGCCTTAACTGGGAAGAAAT GGAAAAAAGCCGGTGCATTCCTGAAATAGATGATTCCGAGTTTTGTATCCGCATTCCGGGAGGAGGTATCACAAAAACACTCTATGATGA AAGCTGTTCTAAAGAAATCCAAATGGCAGTTCTGCTGAAATTTGTTTCAGAAGGGGACAACATCCCAGATGCATTAGGTCTTGTTGAGTA TCTTAATGAGTGGCTTCAGATACTCAAACCACTTGTTAAATGTGCACAGTACTGGCCAACAGATGACCAAGAGATGCTGTTTAAAGAAAC AGGATTCAGTGTGAAGCTCTTGTCAGAAGATGTGAAGTCGTATTATACAGTACATCTACTACAATTAGAAAATATCAATAGTGGTGAAAC CAGAACAATATCTCACTTTCATTATACTACCTGGCCAGATTTTGGAGTCCCTGAATCACCAGCTTCATTTCTCAATTTCTTGTTTAAAGT GAGAGAATCTGGCTCCTTGAACCCTGACCATGGGCCTGCGGTGATCCACTGTAGTGCAGGCATTGGGCGCTCTGGCACCTTCTCTCTGGT AGACACTTGTCTTGTTTTGATGGAAAAAGGAGATGATATTAACATAAAACAAGTGTTACTGAACATGAGAAAATACCGAATGGGTCTTAT TCAGACCCCAGATCAACTGAGATTCTCATACATGGCTATAATAGAAGGAGCAAAATGTATAAAGGGAGATTCTAGTATACAGAAACGATG GAAAGAACTTTCTAAGGAAGACTTATCTCCTGCCTTTGATCATTCACCAAACAAAATAATGACTGAAAAATACAATGGGAACAGAATAGG TCTAGAAGAAGAAAAACTGACAGGTGACCGATGTACAGGACTTTCCTCTAAAATGCAAGATACAATGGAGGAGAACAGTGAGAGTGCTCT ACGGAAACGTATTCGAGAGGACAGAAAGGCCACCACAGCTCAGAAGGTGCAGCAGATGAAACAGAGGCTAAATGAGAATGAACGAAAAAG AAAAAGGCCAAGATTGACAGACACCTAATATTCATGACTTGAGAATATTCTGCAGCTATAAATTTTGAACCATTGATGTGCAAAGCAAGA CCTGAAGCCCACTCCGGAAACTAAAGTGAGGCTCGCTAACCCTCTAGATTGCCTCACAGTTGTTTGTTTACAAAGTAAACTTTACATCCA GGGGATGAAGAGCACCCACCAGCAGAAGACTTTGCAGAACCTTTAATTGGATGTGTTAAGTGTTTTTAATGAGTGTATGAAATGTAGAAA GATGTACAAGAAATAAATTAGGGGAGATTACTTTGTATTGTACTGCCATTCCTACTGTATTTTTATACTTTTTGGCAGCATTAAATATTT >69766_69766_2_PSMG2-PTPN2_PSMG2_chr18_12724618_ENST00000317615_PTPN2_chr18_12825943_ENST00000327283_length(amino acids)=603AA_BP=336 MIVSARRSTSPRAPHPETSAHPIALLARVSESAAGPSSRPPGGLFPPSEPAVSWTGLKGPAPRDSKDPPAPREAPGSRASAFLLPSFLPG PRLVPAGHPTATMFVPCGESAPDLAGFTLLMPAVSVGNVGQLAMDLIISTLNMSKIGYFYTDCLVPMVGNNPYATTEGNSTELSINAEVY SLPSRKLVALQLRSIFIKYKSKPFCEKLLSWVKSSGCARVIVLSSSHSYQRNDLQLRSTPFRYLLTPSMQKSVQNKIKSLNWEEMEKSRC IPEIDDSEFCIRIPGGGITKTLYDESCSKEIQMAVLLKFVSEGDNIPDALGLVEYLNEWLQILKPLVKCAQYWPTDDQEMLFKETGFSVK LLSEDVKSYYTVHLLQLENINSGETRTISHFHYTTWPDFGVPESPASFLNFLFKVRESGSLNPDHGPAVIHCSAGIGRSGTFSLVDTCLV LMEKGDDINIKQVLLNMRKYRMGLIQTPDQLRFSYMAIIEGAKCIKGDSSIQKRWKELSKEDLSPAFDHSPNKIMTEKYNGNRIGLEEEK -------------------------------------------------------------- >69766_69766_3_PSMG2-PTPN2_PSMG2_chr18_12724618_ENST00000317615_PTPN2_chr18_12825943_ENST00000353319_length(transcript)=2426nt_BP=1384nt GGCAGGAGGGAAAGGTTATGGGTCGGCCCGGCGGTCTCTCCCAGCACCCGCGACTCTCACCTTGCTCAGCTGCTGGTGGATGAGCTGCTT CAGCTCGGAGGCTTTCTCCGGAGGCAGCGACATGCTGGCAGCCGGCGTCTCCCCGCCGCTTCTCCCCGCCTCAGATGCCCTAACTGCGCG GCCCCGGCCGGGCCAGGGAGCGTTAGGAGCGACTGGAGCACAAAGCGCCGCAGCCGTTCGCCTAGCGCAGCTCCCGGGGGACGCAACGCC GCGTCAGGCCGGGGGCTGACCTGGAAATGAGGCCCCGGCGGCGGCGGCGCCAACTGTTTTCAAACAGTGGCGGACAAACAGGGCTTGGGG CTGGCCCGCACGCTGCCTGATCGTTTCCGCCCGCCGCTCCACCTCCCCGCGGGCCCCGCACCCCGAGACCTCAGCGCACCCCATCGCCTT GCTTGCCAGGGTCTCCGAAAGCGCTGCTGGCCCCTCTTCGCGGCCACCCGGCGGCCTCTTTCCGCCCTCTGAACCGGCAGTTAGCTGGAC GGGCCTCAAGGGCCCGGCGCCCAGGGACTCAAAGGACCCTCCCGCGCCCCGCGAGGCTCCGGGGTCTCGGGCTTCCGCCTTCTTGCTGCC CTCGTTCTTGCCAGGGCCGCGGTTAGTCCCTGCTGGCCACCCCACTGCGACCATGTTCGTTCCCTGCGGGGAGTCGGCCCCCGACCTTGC CGGCTTCACCCTCCTAATGCCAGCAGTATCTGTTGGAAATGTTGGCCAGCTTGCAATGGATCTGATTATTTCTACACTGAATATGTCTAA GATTGGTTACTTCTATACCGATTGTCTTGTGCCAATGGTTGGAAACAATCCATATGCGACCACAGAAGGAAATTCAACAGAACTTAGCAT AAATGCTGAAGTGTATTCATTGCCTTCAAGAAAGCTGGTGGCTCTACAGTTAAGATCCATTTTTATTAAGTATAAATCAAAGCCATTCTG TGAAAAACTGCTTTCCTGGGTGAAAAGCAGTGGCTGTGCCAGAGTCATTGTTCTTTCAAGCAGTCATTCATATCAGCGTAATGATCTGCA GCTTCGTAGTACTCCCTTCCGGTACCTACTTACACCTTCCATGCAAAAAAGTGTTCAAAATAAAATAAAGAGCCTTAACTGGGAAGAAAT GGAAAAAAGCCGGTGCATTCCTGAAATAGATGATTCCGAGTTTTGTATCCGCATTCCGGGAGGAGGTATCACAAAAACACTCTATGATGA AAGCTGTTCTAAAGAAATCCAAATGGCAGTTCTGCTGAAATTTGTTTCAGAAGGGGACAACATCCCAGATGCATTAGGTCTTGTTGAGTA TCTTAATGAGTGGCTTCAGATACTCAAACCACTTGTTAAATGTGCACAGTACTGGCCAACAGATGACCAAGAGATGCTGTTTAAAGAAAC AGGATTCAGTGTGAAGCTCTTGTCAGAAGATGTGAAGTCGTATTATACAGTACATCTACTACAATTAGAAAATATCAATAGTGGTGAAAC CAGAACAATATCTCACTTTCATTATACTACCTGGCCAGATTTTGGAGTCCCTGAATCACCAGCTTCATTTCTCAATTTCTTGTTTAAAGT GAGAGAATCTGGCTCCTTGAACCCTGACCATGGGCCTGCGGTGATCCACTGTAGTGCAGGCATTGGGCGCTCTGGCACCTTCTCTCTGGT AGACACTTGTCTTGTTTTGATGGAAAAAGGAGATGATATTAACATAAAACAAGTGTTACTGAACATGAGAAAATACCGAATGGGTCTTAT TCAGACCCCAGATCAACTGAGATTCTCATACATGGCTATAATAGAAGGAGCAAAATGTATAAAGGGAGATTCTAGTATACAGAAACGATG GAAAGAACTTTCTAAGGAAGACTTATCTCCTGCCTTTGATCATTCACCAAACAAAATAATGACTGAAAAATACAATGGGAACAGAATAGG TCTAGAAGAAGAAAAACTGACAGGTGACCGATGTACAGGACTTTCCTCTAAAATGCAAGATACAATGGAGGAGAACAGTGAGAGGCCAAG ATTGACAGACACCTAATATTCATGACTTGAGAATATTCTGCAGCTATAAATTTTGAACCATTGATGTGCAAAGCAAGACCTGAAGCCCAC TCCGGAAACTAAAGTGAGGCTCGCTAACCCTCTAGATTGCCTCACAGTTGTTTGTTTACAAAGTAAACTTTACATCCAGGGGATGAAGAG CACCCACCAGCAGAAGACTTTGCAGAACCTTTAATTGGATGTGTTAAGTGTTTTTAATGAGTGTATGAAATGTAGAAAGATGTACAAGAA >69766_69766_3_PSMG2-PTPN2_PSMG2_chr18_12724618_ENST00000317615_PTPN2_chr18_12825943_ENST00000353319_length(amino acids)=569AA_BP=336 MIVSARRSTSPRAPHPETSAHPIALLARVSESAAGPSSRPPGGLFPPSEPAVSWTGLKGPAPRDSKDPPAPREAPGSRASAFLLPSFLPG PRLVPAGHPTATMFVPCGESAPDLAGFTLLMPAVSVGNVGQLAMDLIISTLNMSKIGYFYTDCLVPMVGNNPYATTEGNSTELSINAEVY SLPSRKLVALQLRSIFIKYKSKPFCEKLLSWVKSSGCARVIVLSSSHSYQRNDLQLRSTPFRYLLTPSMQKSVQNKIKSLNWEEMEKSRC IPEIDDSEFCIRIPGGGITKTLYDESCSKEIQMAVLLKFVSEGDNIPDALGLVEYLNEWLQILKPLVKCAQYWPTDDQEMLFKETGFSVK LLSEDVKSYYTVHLLQLENINSGETRTISHFHYTTWPDFGVPESPASFLNFLFKVRESGSLNPDHGPAVIHCSAGIGRSGTFSLVDTCLV LMEKGDDINIKQVLLNMRKYRMGLIQTPDQLRFSYMAIIEGAKCIKGDSSIQKRWKELSKEDLSPAFDHSPNKIMTEKYNGNRIGLEEEK -------------------------------------------------------------- >69766_69766_4_PSMG2-PTPN2_PSMG2_chr18_12724618_ENST00000317615_PTPN2_chr18_12825943_ENST00000591115_length(transcript)=2599nt_BP=1384nt GGCAGGAGGGAAAGGTTATGGGTCGGCCCGGCGGTCTCTCCCAGCACCCGCGACTCTCACCTTGCTCAGCTGCTGGTGGATGAGCTGCTT CAGCTCGGAGGCTTTCTCCGGAGGCAGCGACATGCTGGCAGCCGGCGTCTCCCCGCCGCTTCTCCCCGCCTCAGATGCCCTAACTGCGCG GCCCCGGCCGGGCCAGGGAGCGTTAGGAGCGACTGGAGCACAAAGCGCCGCAGCCGTTCGCCTAGCGCAGCTCCCGGGGGACGCAACGCC GCGTCAGGCCGGGGGCTGACCTGGAAATGAGGCCCCGGCGGCGGCGGCGCCAACTGTTTTCAAACAGTGGCGGACAAACAGGGCTTGGGG CTGGCCCGCACGCTGCCTGATCGTTTCCGCCCGCCGCTCCACCTCCCCGCGGGCCCCGCACCCCGAGACCTCAGCGCACCCCATCGCCTT GCTTGCCAGGGTCTCCGAAAGCGCTGCTGGCCCCTCTTCGCGGCCACCCGGCGGCCTCTTTCCGCCCTCTGAACCGGCAGTTAGCTGGAC GGGCCTCAAGGGCCCGGCGCCCAGGGACTCAAAGGACCCTCCCGCGCCCCGCGAGGCTCCGGGGTCTCGGGCTTCCGCCTTCTTGCTGCC CTCGTTCTTGCCAGGGCCGCGGTTAGTCCCTGCTGGCCACCCCACTGCGACCATGTTCGTTCCCTGCGGGGAGTCGGCCCCCGACCTTGC CGGCTTCACCCTCCTAATGCCAGCAGTATCTGTTGGAAATGTTGGCCAGCTTGCAATGGATCTGATTATTTCTACACTGAATATGTCTAA GATTGGTTACTTCTATACCGATTGTCTTGTGCCAATGGTTGGAAACAATCCATATGCGACCACAGAAGGAAATTCAACAGAACTTAGCAT AAATGCTGAAGTGTATTCATTGCCTTCAAGAAAGCTGGTGGCTCTACAGTTAAGATCCATTTTTATTAAGTATAAATCAAAGCCATTCTG TGAAAAACTGCTTTCCTGGGTGAAAAGCAGTGGCTGTGCCAGAGTCATTGTTCTTTCAAGCAGTCATTCATATCAGCGTAATGATCTGCA GCTTCGTAGTACTCCCTTCCGGTACCTACTTACACCTTCCATGCAAAAAAGTGTTCAAAATAAAATAAAGAGCCTTAACTGGGAAGAAAT GGAAAAAAGCCGGTGCATTCCTGAAATAGATGATTCCGAGTTTTGTATCCGCATTCCGGGAGGAGGTATCACAAAAACACTCTATGATGA AAGCTGTTCTAAAGAAATCCAAATGGCAGTTCTGCTGAAATTTGTTTCAGAAGGGGACAACATCCCAGATGCATTAGGTCTTGTTGAGTA TCTTAATGAGTGGCTTCAGATACTCAAACCACTTGTTAAATGTGCACAGTACTGGCCAACAGATGACCAAGAGATGCTGTTTAAAGAAAC AGGATTCAGTGTGAAGCTCTTGTCAGAAGATGTGAAGTCGTATTATACAGTACATCTACTACAATTAGAAAATATCAATTATATTGAGAA CTTGTGGATCACACTGTATTTGAAATTATTAATGCTGGATGTTAAAAGGTCACTAAAAAGTGGTGAAACCAGAACAATATCTCACTTTCA TTATACTACCTGGCCAGATTTTGGAGTCCCTGAATCACCAGCTTCATTTCTCAATTTCTTGTTTAAAGTGAGAGAATCTGGCTCCTTGAA CCCTGACCATGGGCCTGCGGTGATCCACTGTAGTGCAGGCATTGGGCGCTCTGGCACCTTCTCTCTGGTAGACACTTGTCTTGTTTTGAT GGAAAAAGGAGATGATATTAACATAAAACAAGTGTTACTGAACATGAGAAAATACCGAATGGGTCTTATTCAGACCCCAGATCAACTGAG ATTCTCATACATGGCTATAATAGAAGGAGCAAAATGTATAAAGGGAGATTCTAGTATACAGAAACGATGGAAAGAACTTTCTAAGGAAGA CTTATCTCCTGCCTTTGATCATTCACCAAACAAAATAATGACTGAAAAATACAATGGGAACAGAATAGGTCTAGAAGAAGAAAAACTGAC AGGTGACCGATGTACAGGACTTTCCTCTAAAATGCAAGATACAATGGAGGAGAACAGTGAGAGTGCTCTACGGAAACGTATTCGAGAGGA CAGAAAGGCCACCACAGCTCAGAAGGTGCAGCAGATGAAACAGAGGCTAAATGAGAATGAACGAAAAAGAAAAAGGCCAAGATTGACAGA CACCTAATATTCATGACTTGAGAATATTCTGCAGCTATAAATTTTGAACCATTGATGTGCAAAGCAAGACCTGAAGCCCACTCCGGAAAC TAAAGTGAGGCTCGCTAACCCTCTAGATTGCCTCACAGTTGTTTGTTTACAAAGTAAACTTTACATCCAGGGGATGAAGAGCACCCACCA GCAGAAGACTTTGCAGAACCTTTAATTGGATGTGTTAAGTGTTTTTAATGAGTGTATGAAATGTAGAAAGATGTACAAGAAATAAATTAG >69766_69766_4_PSMG2-PTPN2_PSMG2_chr18_12724618_ENST00000317615_PTPN2_chr18_12825943_ENST00000591115_length(amino acids)=626AA_BP=336 MIVSARRSTSPRAPHPETSAHPIALLARVSESAAGPSSRPPGGLFPPSEPAVSWTGLKGPAPRDSKDPPAPREAPGSRASAFLLPSFLPG PRLVPAGHPTATMFVPCGESAPDLAGFTLLMPAVSVGNVGQLAMDLIISTLNMSKIGYFYTDCLVPMVGNNPYATTEGNSTELSINAEVY SLPSRKLVALQLRSIFIKYKSKPFCEKLLSWVKSSGCARVIVLSSSHSYQRNDLQLRSTPFRYLLTPSMQKSVQNKIKSLNWEEMEKSRC IPEIDDSEFCIRIPGGGITKTLYDESCSKEIQMAVLLKFVSEGDNIPDALGLVEYLNEWLQILKPLVKCAQYWPTDDQEMLFKETGFSVK LLSEDVKSYYTVHLLQLENINYIENLWITLYLKLLMLDVKRSLKSGETRTISHFHYTTWPDFGVPESPASFLNFLFKVRESGSLNPDHGP AVIHCSAGIGRSGTFSLVDTCLVLMEKGDDINIKQVLLNMRKYRMGLIQTPDQLRFSYMAIIEGAKCIKGDSSIQKRWKELSKEDLSPAF -------------------------------------------------------------- >69766_69766_5_PSMG2-PTPN2_PSMG2_chr18_12724618_ENST00000585331_PTPN2_chr18_12825943_ENST00000309660_length(transcript)=3694nt_BP=681nt TGGTTGAATACCTCCCTCTCCACTCCCATCTTCAGGCCAGCAGTATCTGTTGGAAATGTTGGCCAGCTTGCAATGGATCTGATTATTTCT ACACTGAATATGTCTAAGATTGGTTACTTCTATACCGATTGTCTTGTGCCAATGGTTGGAAACAATCCATATGCGACCACAGAAGGAAAT TCAACAGAACTTAGCATAAATGCTGAAGTGTATTCATTGCCTTCAAGAAAGCTGGTGGCTCTACAGTTAAGATCCATTTTTATTAAGTAT AAATCAAAGCCATTCTGTGAAAAACTGCTTTCCTGGGTGAAAAGCAGTGGCTGTGCCAGAGTCATTGTTCTTTCAAGCAGTCATTCATAT CAGCGTAATGATCTGCAGCTTCGTAGTACTCCCTTCCGGTACCTACTTACACCTTCCATGCAAAAAAGTGTTCAAAATAAAATAAAGAGC CTTAACTGGGAAGAAATGGAAAAAAGCCGGTGCATTCCTGAAATAGATGATTCCGAGTTTTGTATCCGCATTCCGGGAGGAGGTATCACA AAAACACTCTATGATGAAAGCTGTTCTAAAGAAATCCAAATGGCAGTTCTGCTGAAATTTGTTTCAGAAGGGGACAACATCCCAGATGCA TTAGGTCTTGTTGAGTATCTTAATGAGTGGCTTCAGATACTCAAACCACTTGTTAAATGTGCACAGTACTGGCCAACAGATGACCAAGAG ATGCTGTTTAAAGAAACAGGATTCAGTGTGAAGCTCTTGTCAGAAGATGTGAAGTCGTATTATACAGTACATCTACTACAATTAGAAAAT ATCAATAGTGGTGAAACCAGAACAATATCTCACTTTCATTATACTACCTGGCCAGATTTTGGAGTCCCTGAATCACCAGCTTCATTTCTC AATTTCTTGTTTAAAGTGAGAGAATCTGGCTCCTTGAACCCTGACCATGGGCCTGCGGTGATCCACTGTAGTGCAGGCATTGGGCGCTCT GGCACCTTCTCTCTGGTAGACACTTGTCTTGTTTTGATGGAAAAAGGAGATGATATTAACATAAAACAAGTGTTACTGAACATGAGAAAA TACCGAATGGGTCTTATTCAGACCCCAGATCAACTGAGATTCTCATACATGGCTATAATAGAAGGAGCAAAATGTATAAAGGGAGATTCT AGTATACAGAAACGATGGAAAGAACTTTCTAAGGAAGACTTATCTCCTGCCTTTGATCATTCACCAAACAAAATAATGACTGAAAAATAC AATGGGAACAGAATAGGTCTAGAAGAAGAAAAACTGACAGGTGACCGATGTACAGGACTTTCCTCTAAAATGCAAGATACAATGGAGGAG AACAGTGAGAGTGCTCTACGGAAACGTATTCGAGAGGACAGAAAGGCCACCACAGCTCAGAAGGTGCAGCAGATGAAACAGAGGCTAAAT GAGAATGAACGAAAAAGAAAAAGGTGGTTATATTGGCAACCTATTCTCACTAAGATGGGGTTTATGTCAGTCATTTTGGTTGGCGCTTTT GTTGGCTGGACACTGTTTTTTCAGCAAAATGCCCTATAAACAATTAATTTTGCCCAGCAAGCTTCTGCACTAGTAACTGACAGTGCTACA TTAATCATAGGGGTTTGTCTGCAGCAAACGCCTCATATCCCAAAAACGGTGCAGTAGAATAGACATCAACCAGATAAGTGATATTTACAG TCACAAGCCCAACATCTCAGGACTCTTGACTGCAGGTTCCTCTGAACCCCAAACTGTAAATGGCTGTCTAAAATAAAGACATTCATGTTT GTTAAAAACTGGTAAATTTTGCAACTGTATTCATACATGTCAAACACAGTATTTCACCTGACCAACATTGAGATATCCTTTATCACAGGA TTTGTTTTTGGAGGCTATCTGGATTTTAACCTGCACTTGATATAAGCAATAAATATTGTGGTTTTATCTACGTTATTGGAAAGAAAATGA CATTTAAATAATGTGTGTAATGTATAATGTACTATTGACATGGGCATCAACACTTTTATTCTTAAGCATTTCAGGGTAAATATATTTTAT AAGTATCTATTTAATCTTTTGTAGTTAACTGTACTTTTTAAGAGCTCAATTTGAAAAATCTGTTACTAAAAAAATAAATTGTATGTCGAT TGAATTGTACTGGATACATTTTCCATTTTTCTAAAGAGAAGTTTGATATGAGCAGTTAGAAGTTGGAATAAGCAATTTCTACTATATATT GCATTTCTTTTATGTTTTACAGTTTTCCCCATTTTAAAAAGAAAAGCAAACAAAGAAACAAAAGTTTTTCCTAAAAATATCTTTGAAGGA AAATTCTCCTTACTGGGATAGTCAGGTAAACAGTTGGTCAAGACTTTGTAAAGAAATTGGTTTCTGTAAATCCCATTATTGATATGTTTA TTTTTCATGAAAATTTCAATGTAGTTGGGGTAGATTATGATTTAGGAAGCAAAAGTAAGAAGCAGCATTTTATGATTCATAATTTCAGTT TACTAGACTGAAGTTTTGAAGTAAACACTTTTCAGTTTCTTTCTACTTCAATAAATAGTATGATTATATGCAAACCTTACATTGTCATTT TAACTTAATGAATATTTTTTAAAGCAAACTGTTTAATGAATTTAACTGCTCATTTGAATGCTAGCTTTCCTCAGATTTCAACATTCCATT CAGTGTTTAATTTGTCTTACTTAAACTTGAAATTGTTGTTACAAATTTAATTGCTAGGAGGCATGGATAGCATACATTATTATGGATAGC ATACCTTATTTCAGTGGTTTTCAAACTATGCTCATTGGATGTCCAGGTGGGTCAAGAGGTTACTTTCAACCACAGCATCTCTGCCTTGTC TCTTTATATGCCACATAAGATTTCTGCATAAGGCTTAAGTATTTTAAAGGGGGCAGTTATCATTTAAAAACAGTTTGGTCGGGCGCGGTG GCTCATGCCTGTAATCCCAGCACTTTGGGAGGCTGAAGTGGGCAGATCACCTGAGGTCAGGAGTTCAAGACCAGCCTGGCCAACGTGGTG AAACACCATCTCTACTAAAAATGCAAAAATTAGCTGGGCATGGTGGAGGGCACCTGTAATCTCAGCTACTCAGGAGGCTGAGGTAGGAGA ATTGCTTGAACCCAGGAGATGGAGGTTGCAGTGAGCTGAGATCACGTCACTGCACTCCAGCCAGGGCGACAGAGCGAGACTCCATCTCAA AAGAAACAAACAAAAAAAACAGTTTGGGCCGGGTGTGGTGGCTCACGCTTGTAATCCCAGCACTTCGGAAGGCCAAGGCGGGCGGATCAC GAGGTCAAGAGATGGAGACTGTCCTGGCCAACATGGTGAAATCCCTTCTTTACTAAAAATACAAAAATTATCTGGGCGTGGTGGTGCATG CCTGTAGTCCCAGCTCCTTGGGAGGCTAAGGCAGGAGAATCACTTGAACCCGGGAGGCAGAGGTTGCAGTGAGCCGAGATTGCACCACTG CACTCCAGCCTGGCAACAGAGCAAGACTTCGTCTCAAAAAAAAAAAAAAAAAAAGTTTGAAAACCATTGGTATAGATAGATATTTTGAAT TGATTTGCATAGTCTCCTTGAATGTGTTAAATTATGTTGAAAGTATGAAAGCAGGATGTAGGTGGTACTACATATTAAATAAGATTTATA >69766_69766_5_PSMG2-PTPN2_PSMG2_chr18_12724618_ENST00000585331_PTPN2_chr18_12825943_ENST00000309660_length(amino acids)=521AA_BP=226 MNTSLSTPIFRPAVSVGNVGQLAMDLIISTLNMSKIGYFYTDCLVPMVGNNPYATTEGNSTELSINAEVYSLPSRKLVALQLRSIFIKYK SKPFCEKLLSWVKSSGCARVIVLSSSHSYQRNDLQLRSTPFRYLLTPSMQKSVQNKIKSLNWEEMEKSRCIPEIDDSEFCIRIPGGGITK TLYDESCSKEIQMAVLLKFVSEGDNIPDALGLVEYLNEWLQILKPLVKCAQYWPTDDQEMLFKETGFSVKLLSEDVKSYYTVHLLQLENI NSGETRTISHFHYTTWPDFGVPESPASFLNFLFKVRESGSLNPDHGPAVIHCSAGIGRSGTFSLVDTCLVLMEKGDDINIKQVLLNMRKY RMGLIQTPDQLRFSYMAIIEGAKCIKGDSSIQKRWKELSKEDLSPAFDHSPNKIMTEKYNGNRIGLEEEKLTGDRCTGLSSKMQDTMEEN -------------------------------------------------------------- >69766_69766_6_PSMG2-PTPN2_PSMG2_chr18_12724618_ENST00000585331_PTPN2_chr18_12825943_ENST00000327283_length(transcript)=1830nt_BP=681nt TGGTTGAATACCTCCCTCTCCACTCCCATCTTCAGGCCAGCAGTATCTGTTGGAAATGTTGGCCAGCTTGCAATGGATCTGATTATTTCT ACACTGAATATGTCTAAGATTGGTTACTTCTATACCGATTGTCTTGTGCCAATGGTTGGAAACAATCCATATGCGACCACAGAAGGAAAT TCAACAGAACTTAGCATAAATGCTGAAGTGTATTCATTGCCTTCAAGAAAGCTGGTGGCTCTACAGTTAAGATCCATTTTTATTAAGTAT AAATCAAAGCCATTCTGTGAAAAACTGCTTTCCTGGGTGAAAAGCAGTGGCTGTGCCAGAGTCATTGTTCTTTCAAGCAGTCATTCATAT CAGCGTAATGATCTGCAGCTTCGTAGTACTCCCTTCCGGTACCTACTTACACCTTCCATGCAAAAAAGTGTTCAAAATAAAATAAAGAGC CTTAACTGGGAAGAAATGGAAAAAAGCCGGTGCATTCCTGAAATAGATGATTCCGAGTTTTGTATCCGCATTCCGGGAGGAGGTATCACA AAAACACTCTATGATGAAAGCTGTTCTAAAGAAATCCAAATGGCAGTTCTGCTGAAATTTGTTTCAGAAGGGGACAACATCCCAGATGCA TTAGGTCTTGTTGAGTATCTTAATGAGTGGCTTCAGATACTCAAACCACTTGTTAAATGTGCACAGTACTGGCCAACAGATGACCAAGAG ATGCTGTTTAAAGAAACAGGATTCAGTGTGAAGCTCTTGTCAGAAGATGTGAAGTCGTATTATACAGTACATCTACTACAATTAGAAAAT ATCAATAGTGGTGAAACCAGAACAATATCTCACTTTCATTATACTACCTGGCCAGATTTTGGAGTCCCTGAATCACCAGCTTCATTTCTC AATTTCTTGTTTAAAGTGAGAGAATCTGGCTCCTTGAACCCTGACCATGGGCCTGCGGTGATCCACTGTAGTGCAGGCATTGGGCGCTCT GGCACCTTCTCTCTGGTAGACACTTGTCTTGTTTTGATGGAAAAAGGAGATGATATTAACATAAAACAAGTGTTACTGAACATGAGAAAA TACCGAATGGGTCTTATTCAGACCCCAGATCAACTGAGATTCTCATACATGGCTATAATAGAAGGAGCAAAATGTATAAAGGGAGATTCT AGTATACAGAAACGATGGAAAGAACTTTCTAAGGAAGACTTATCTCCTGCCTTTGATCATTCACCAAACAAAATAATGACTGAAAAATAC AATGGGAACAGAATAGGTCTAGAAGAAGAAAAACTGACAGGTGACCGATGTACAGGACTTTCCTCTAAAATGCAAGATACAATGGAGGAG AACAGTGAGAGTGCTCTACGGAAACGTATTCGAGAGGACAGAAAGGCCACCACAGCTCAGAAGGTGCAGCAGATGAAACAGAGGCTAAAT GAGAATGAACGAAAAAGAAAAAGGCCAAGATTGACAGACACCTAATATTCATGACTTGAGAATATTCTGCAGCTATAAATTTTGAACCAT TGATGTGCAAAGCAAGACCTGAAGCCCACTCCGGAAACTAAAGTGAGGCTCGCTAACCCTCTAGATTGCCTCACAGTTGTTTGTTTACAA AGTAAACTTTACATCCAGGGGATGAAGAGCACCCACCAGCAGAAGACTTTGCAGAACCTTTAATTGGATGTGTTAAGTGTTTTTAATGAG TGTATGAAATGTAGAAAGATGTACAAGAAATAAATTAGGGGAGATTACTTTGTATTGTACTGCCATTCCTACTGTATTTTTATACTTTTT >69766_69766_6_PSMG2-PTPN2_PSMG2_chr18_12724618_ENST00000585331_PTPN2_chr18_12825943_ENST00000327283_length(amino acids)=493AA_BP=226 MNTSLSTPIFRPAVSVGNVGQLAMDLIISTLNMSKIGYFYTDCLVPMVGNNPYATTEGNSTELSINAEVYSLPSRKLVALQLRSIFIKYK SKPFCEKLLSWVKSSGCARVIVLSSSHSYQRNDLQLRSTPFRYLLTPSMQKSVQNKIKSLNWEEMEKSRCIPEIDDSEFCIRIPGGGITK TLYDESCSKEIQMAVLLKFVSEGDNIPDALGLVEYLNEWLQILKPLVKCAQYWPTDDQEMLFKETGFSVKLLSEDVKSYYTVHLLQLENI NSGETRTISHFHYTTWPDFGVPESPASFLNFLFKVRESGSLNPDHGPAVIHCSAGIGRSGTFSLVDTCLVLMEKGDDINIKQVLLNMRKY RMGLIQTPDQLRFSYMAIIEGAKCIKGDSSIQKRWKELSKEDLSPAFDHSPNKIMTEKYNGNRIGLEEEKLTGDRCTGLSSKMQDTMEEN -------------------------------------------------------------- >69766_69766_7_PSMG2-PTPN2_PSMG2_chr18_12724618_ENST00000585331_PTPN2_chr18_12825943_ENST00000353319_length(transcript)=1723nt_BP=681nt TGGTTGAATACCTCCCTCTCCACTCCCATCTTCAGGCCAGCAGTATCTGTTGGAAATGTTGGCCAGCTTGCAATGGATCTGATTATTTCT ACACTGAATATGTCTAAGATTGGTTACTTCTATACCGATTGTCTTGTGCCAATGGTTGGAAACAATCCATATGCGACCACAGAAGGAAAT TCAACAGAACTTAGCATAAATGCTGAAGTGTATTCATTGCCTTCAAGAAAGCTGGTGGCTCTACAGTTAAGATCCATTTTTATTAAGTAT AAATCAAAGCCATTCTGTGAAAAACTGCTTTCCTGGGTGAAAAGCAGTGGCTGTGCCAGAGTCATTGTTCTTTCAAGCAGTCATTCATAT CAGCGTAATGATCTGCAGCTTCGTAGTACTCCCTTCCGGTACCTACTTACACCTTCCATGCAAAAAAGTGTTCAAAATAAAATAAAGAGC CTTAACTGGGAAGAAATGGAAAAAAGCCGGTGCATTCCTGAAATAGATGATTCCGAGTTTTGTATCCGCATTCCGGGAGGAGGTATCACA AAAACACTCTATGATGAAAGCTGTTCTAAAGAAATCCAAATGGCAGTTCTGCTGAAATTTGTTTCAGAAGGGGACAACATCCCAGATGCA TTAGGTCTTGTTGAGTATCTTAATGAGTGGCTTCAGATACTCAAACCACTTGTTAAATGTGCACAGTACTGGCCAACAGATGACCAAGAG ATGCTGTTTAAAGAAACAGGATTCAGTGTGAAGCTCTTGTCAGAAGATGTGAAGTCGTATTATACAGTACATCTACTACAATTAGAAAAT ATCAATAGTGGTGAAACCAGAACAATATCTCACTTTCATTATACTACCTGGCCAGATTTTGGAGTCCCTGAATCACCAGCTTCATTTCTC AATTTCTTGTTTAAAGTGAGAGAATCTGGCTCCTTGAACCCTGACCATGGGCCTGCGGTGATCCACTGTAGTGCAGGCATTGGGCGCTCT GGCACCTTCTCTCTGGTAGACACTTGTCTTGTTTTGATGGAAAAAGGAGATGATATTAACATAAAACAAGTGTTACTGAACATGAGAAAA TACCGAATGGGTCTTATTCAGACCCCAGATCAACTGAGATTCTCATACATGGCTATAATAGAAGGAGCAAAATGTATAAAGGGAGATTCT AGTATACAGAAACGATGGAAAGAACTTTCTAAGGAAGACTTATCTCCTGCCTTTGATCATTCACCAAACAAAATAATGACTGAAAAATAC AATGGGAACAGAATAGGTCTAGAAGAAGAAAAACTGACAGGTGACCGATGTACAGGACTTTCCTCTAAAATGCAAGATACAATGGAGGAG AACAGTGAGAGGCCAAGATTGACAGACACCTAATATTCATGACTTGAGAATATTCTGCAGCTATAAATTTTGAACCATTGATGTGCAAAG CAAGACCTGAAGCCCACTCCGGAAACTAAAGTGAGGCTCGCTAACCCTCTAGATTGCCTCACAGTTGTTTGTTTACAAAGTAAACTTTAC ATCCAGGGGATGAAGAGCACCCACCAGCAGAAGACTTTGCAGAACCTTTAATTGGATGTGTTAAGTGTTTTTAATGAGTGTATGAAATGT AGAAAGATGTACAAGAAATAAATTAGGGGAGATTACTTTGTATTGTACTGCCATTCCTACTGTATTTTTATACTTTTTGGCAGCATTAAA >69766_69766_7_PSMG2-PTPN2_PSMG2_chr18_12724618_ENST00000585331_PTPN2_chr18_12825943_ENST00000353319_length(amino acids)=459AA_BP=226 MNTSLSTPIFRPAVSVGNVGQLAMDLIISTLNMSKIGYFYTDCLVPMVGNNPYATTEGNSTELSINAEVYSLPSRKLVALQLRSIFIKYK SKPFCEKLLSWVKSSGCARVIVLSSSHSYQRNDLQLRSTPFRYLLTPSMQKSVQNKIKSLNWEEMEKSRCIPEIDDSEFCIRIPGGGITK TLYDESCSKEIQMAVLLKFVSEGDNIPDALGLVEYLNEWLQILKPLVKCAQYWPTDDQEMLFKETGFSVKLLSEDVKSYYTVHLLQLENI NSGETRTISHFHYTTWPDFGVPESPASFLNFLFKVRESGSLNPDHGPAVIHCSAGIGRSGTFSLVDTCLVLMEKGDDINIKQVLLNMRKY RMGLIQTPDQLRFSYMAIIEGAKCIKGDSSIQKRWKELSKEDLSPAFDHSPNKIMTEKYNGNRIGLEEEKLTGDRCTGLSSKMQDTMEEN -------------------------------------------------------------- >69766_69766_8_PSMG2-PTPN2_PSMG2_chr18_12724618_ENST00000585331_PTPN2_chr18_12825943_ENST00000591115_length(transcript)=1896nt_BP=681nt TGGTTGAATACCTCCCTCTCCACTCCCATCTTCAGGCCAGCAGTATCTGTTGGAAATGTTGGCCAGCTTGCAATGGATCTGATTATTTCT ACACTGAATATGTCTAAGATTGGTTACTTCTATACCGATTGTCTTGTGCCAATGGTTGGAAACAATCCATATGCGACCACAGAAGGAAAT TCAACAGAACTTAGCATAAATGCTGAAGTGTATTCATTGCCTTCAAGAAAGCTGGTGGCTCTACAGTTAAGATCCATTTTTATTAAGTAT AAATCAAAGCCATTCTGTGAAAAACTGCTTTCCTGGGTGAAAAGCAGTGGCTGTGCCAGAGTCATTGTTCTTTCAAGCAGTCATTCATAT CAGCGTAATGATCTGCAGCTTCGTAGTACTCCCTTCCGGTACCTACTTACACCTTCCATGCAAAAAAGTGTTCAAAATAAAATAAAGAGC CTTAACTGGGAAGAAATGGAAAAAAGCCGGTGCATTCCTGAAATAGATGATTCCGAGTTTTGTATCCGCATTCCGGGAGGAGGTATCACA AAAACACTCTATGATGAAAGCTGTTCTAAAGAAATCCAAATGGCAGTTCTGCTGAAATTTGTTTCAGAAGGGGACAACATCCCAGATGCA TTAGGTCTTGTTGAGTATCTTAATGAGTGGCTTCAGATACTCAAACCACTTGTTAAATGTGCACAGTACTGGCCAACAGATGACCAAGAG ATGCTGTTTAAAGAAACAGGATTCAGTGTGAAGCTCTTGTCAGAAGATGTGAAGTCGTATTATACAGTACATCTACTACAATTAGAAAAT ATCAATTATATTGAGAACTTGTGGATCACACTGTATTTGAAATTATTAATGCTGGATGTTAAAAGGTCACTAAAAAGTGGTGAAACCAGA ACAATATCTCACTTTCATTATACTACCTGGCCAGATTTTGGAGTCCCTGAATCACCAGCTTCATTTCTCAATTTCTTGTTTAAAGTGAGA GAATCTGGCTCCTTGAACCCTGACCATGGGCCTGCGGTGATCCACTGTAGTGCAGGCATTGGGCGCTCTGGCACCTTCTCTCTGGTAGAC ACTTGTCTTGTTTTGATGGAAAAAGGAGATGATATTAACATAAAACAAGTGTTACTGAACATGAGAAAATACCGAATGGGTCTTATTCAG ACCCCAGATCAACTGAGATTCTCATACATGGCTATAATAGAAGGAGCAAAATGTATAAAGGGAGATTCTAGTATACAGAAACGATGGAAA GAACTTTCTAAGGAAGACTTATCTCCTGCCTTTGATCATTCACCAAACAAAATAATGACTGAAAAATACAATGGGAACAGAATAGGTCTA GAAGAAGAAAAACTGACAGGTGACCGATGTACAGGACTTTCCTCTAAAATGCAAGATACAATGGAGGAGAACAGTGAGAGTGCTCTACGG AAACGTATTCGAGAGGACAGAAAGGCCACCACAGCTCAGAAGGTGCAGCAGATGAAACAGAGGCTAAATGAGAATGAACGAAAAAGAAAA AGGCCAAGATTGACAGACACCTAATATTCATGACTTGAGAATATTCTGCAGCTATAAATTTTGAACCATTGATGTGCAAAGCAAGACCTG AAGCCCACTCCGGAAACTAAAGTGAGGCTCGCTAACCCTCTAGATTGCCTCACAGTTGTTTGTTTACAAAGTAAACTTTACATCCAGGGG ATGAAGAGCACCCACCAGCAGAAGACTTTGCAGAACCTTTAATTGGATGTGTTAAGTGTTTTTAATGAGTGTATGAAATGTAGAAAGATG TACAAGAAATAAATTAGGGGAGATTACTTTGTATTGTACTGCCATTCCTACTGTATTTTTATACTTTTTGGCAGCATTAAATATTTTTGT >69766_69766_8_PSMG2-PTPN2_PSMG2_chr18_12724618_ENST00000585331_PTPN2_chr18_12825943_ENST00000591115_length(amino acids)=516AA_BP=226 MNTSLSTPIFRPAVSVGNVGQLAMDLIISTLNMSKIGYFYTDCLVPMVGNNPYATTEGNSTELSINAEVYSLPSRKLVALQLRSIFIKYK SKPFCEKLLSWVKSSGCARVIVLSSSHSYQRNDLQLRSTPFRYLLTPSMQKSVQNKIKSLNWEEMEKSRCIPEIDDSEFCIRIPGGGITK TLYDESCSKEIQMAVLLKFVSEGDNIPDALGLVEYLNEWLQILKPLVKCAQYWPTDDQEMLFKETGFSVKLLSEDVKSYYTVHLLQLENI NYIENLWITLYLKLLMLDVKRSLKSGETRTISHFHYTTWPDFGVPESPASFLNFLFKVRESGSLNPDHGPAVIHCSAGIGRSGTFSLVDT CLVLMEKGDDINIKQVLLNMRKYRMGLIQTPDQLRFSYMAIIEGAKCIKGDSSIQKRWKELSKEDLSPAFDHSPNKIMTEKYNGNRIGLE -------------------------------------------------------------- >69766_69766_9_PSMG2-PTPN2_PSMG2_chr18_12724618_ENST00000590217_PTPN2_chr18_12825943_ENST00000309660_length(transcript)=3928nt_BP=915nt TCCGGGGTCTCGGGCTTCCGCCTTCTTGCTGCCCTCGTTCTTGCCAGGGCCGCGGTTAGTCCCTGCTGGCCACCCCACTGCGACCATGTT CGTTCCCTGCGGGGAGTCGGCCCCCGACCTTGCCGGCTTCACCCTCCTAATGCCAGCAGTATCTGTTGGAAATGTTGGCCAGCTTGCAAT GGATCTGATTATTTCTACACTGAATATGTCTAAGATTGGTTACTTCTATACCGATTGTCTTGTGCCAATGGTTGGAAACAATCCATATGC GACCACAGAAGGAAATTCAACAGAACTTAGCATAAATGCTGAAGTGTATTCATTGCCTTCAAGAAAGCTGGTGGCTCTACAGTTAAGATC CATTTTTATTAAGTATAAATCAAAGCCATTCTGTGAAAAACTGCTTTCCTGGGTGAAAAGCAGTGGCTGTGCCAGAGTCATTGTTCTTTC AAGCAGTCATTCATATCAGCGTAATGATCTGCAGCTTCGTAGTACTCCCTTCCGGTACCTACTTACACCTTCCATGCAAAAAAGTGTTCA AAATAAAATAAAGAGCCTTAACTGGGAAGAAATGGAAAAAAGCCGGTGCATTCCTGAAATAGATGATTCCGAGTTTTGTATCCGCATTCC GGGAGGAGGTATCACAAAAACACTCTATGATGAAAGGTAAGTTCTATTATAGCTTAAGCCTCTTCTTTGTCTGGTTGTATTCATTAACTC GCACTTTATATACTACCTAAGTAGACCAAGTAAGTGAACGTTTGTATTAAATATAGACATATCTTTACATAAAATTTAGTTTAAGCTGAA CTTTTGAAAATTAGAGGACAGTTAACCAACCTATTATTTACAGTTTTTTCATTAAAGCTGACTTTCCAAAAAGGAAAATCCTTAGTTCTT CATTGTACTTACTATGTTAAATGTGCACAGTACTGGCCAACAGATGACCAAGAGATGCTGTTTAAAGAAACAGGATTCAGTGTGAAGCTC TTGTCAGAAGATGTGAAGTCGTATTATACAGTACATCTACTACAATTAGAAAATATCAATAGTGGTGAAACCAGAACAATATCTCACTTT CATTATACTACCTGGCCAGATTTTGGAGTCCCTGAATCACCAGCTTCATTTCTCAATTTCTTGTTTAAAGTGAGAGAATCTGGCTCCTTG AACCCTGACCATGGGCCTGCGGTGATCCACTGTAGTGCAGGCATTGGGCGCTCTGGCACCTTCTCTCTGGTAGACACTTGTCTTGTTTTG ATGGAAAAAGGAGATGATATTAACATAAAACAAGTGTTACTGAACATGAGAAAATACCGAATGGGTCTTATTCAGACCCCAGATCAACTG AGATTCTCATACATGGCTATAATAGAAGGAGCAAAATGTATAAAGGGAGATTCTAGTATACAGAAACGATGGAAAGAACTTTCTAAGGAA GACTTATCTCCTGCCTTTGATCATTCACCAAACAAAATAATGACTGAAAAATACAATGGGAACAGAATAGGTCTAGAAGAAGAAAAACTG ACAGGTGACCGATGTACAGGACTTTCCTCTAAAATGCAAGATACAATGGAGGAGAACAGTGAGAGTGCTCTACGGAAACGTATTCGAGAG GACAGAAAGGCCACCACAGCTCAGAAGGTGCAGCAGATGAAACAGAGGCTAAATGAGAATGAACGAAAAAGAAAAAGGTGGTTATATTGG CAACCTATTCTCACTAAGATGGGGTTTATGTCAGTCATTTTGGTTGGCGCTTTTGTTGGCTGGACACTGTTTTTTCAGCAAAATGCCCTA TAAACAATTAATTTTGCCCAGCAAGCTTCTGCACTAGTAACTGACAGTGCTACATTAATCATAGGGGTTTGTCTGCAGCAAACGCCTCAT ATCCCAAAAACGGTGCAGTAGAATAGACATCAACCAGATAAGTGATATTTACAGTCACAAGCCCAACATCTCAGGACTCTTGACTGCAGG TTCCTCTGAACCCCAAACTGTAAATGGCTGTCTAAAATAAAGACATTCATGTTTGTTAAAAACTGGTAAATTTTGCAACTGTATTCATAC ATGTCAAACACAGTATTTCACCTGACCAACATTGAGATATCCTTTATCACAGGATTTGTTTTTGGAGGCTATCTGGATTTTAACCTGCAC TTGATATAAGCAATAAATATTGTGGTTTTATCTACGTTATTGGAAAGAAAATGACATTTAAATAATGTGTGTAATGTATAATGTACTATT GACATGGGCATCAACACTTTTATTCTTAAGCATTTCAGGGTAAATATATTTTATAAGTATCTATTTAATCTTTTGTAGTTAACTGTACTT TTTAAGAGCTCAATTTGAAAAATCTGTTACTAAAAAAATAAATTGTATGTCGATTGAATTGTACTGGATACATTTTCCATTTTTCTAAAG AGAAGTTTGATATGAGCAGTTAGAAGTTGGAATAAGCAATTTCTACTATATATTGCATTTCTTTTATGTTTTACAGTTTTCCCCATTTTA AAAAGAAAAGCAAACAAAGAAACAAAAGTTTTTCCTAAAAATATCTTTGAAGGAAAATTCTCCTTACTGGGATAGTCAGGTAAACAGTTG GTCAAGACTTTGTAAAGAAATTGGTTTCTGTAAATCCCATTATTGATATGTTTATTTTTCATGAAAATTTCAATGTAGTTGGGGTAGATT ATGATTTAGGAAGCAAAAGTAAGAAGCAGCATTTTATGATTCATAATTTCAGTTTACTAGACTGAAGTTTTGAAGTAAACACTTTTCAGT TTCTTTCTACTTCAATAAATAGTATGATTATATGCAAACCTTACATTGTCATTTTAACTTAATGAATATTTTTTAAAGCAAACTGTTTAA TGAATTTAACTGCTCATTTGAATGCTAGCTTTCCTCAGATTTCAACATTCCATTCAGTGTTTAATTTGTCTTACTTAAACTTGAAATTGT TGTTACAAATTTAATTGCTAGGAGGCATGGATAGCATACATTATTATGGATAGCATACCTTATTTCAGTGGTTTTCAAACTATGCTCATT GGATGTCCAGGTGGGTCAAGAGGTTACTTTCAACCACAGCATCTCTGCCTTGTCTCTTTATATGCCACATAAGATTTCTGCATAAGGCTT AAGTATTTTAAAGGGGGCAGTTATCATTTAAAAACAGTTTGGTCGGGCGCGGTGGCTCATGCCTGTAATCCCAGCACTTTGGGAGGCTGA AGTGGGCAGATCACCTGAGGTCAGGAGTTCAAGACCAGCCTGGCCAACGTGGTGAAACACCATCTCTACTAAAAATGCAAAAATTAGCTG GGCATGGTGGAGGGCACCTGTAATCTCAGCTACTCAGGAGGCTGAGGTAGGAGAATTGCTTGAACCCAGGAGATGGAGGTTGCAGTGAGC TGAGATCACGTCACTGCACTCCAGCCAGGGCGACAGAGCGAGACTCCATCTCAAAAGAAACAAACAAAAAAAACAGTTTGGGCCGGGTGT GGTGGCTCACGCTTGTAATCCCAGCACTTCGGAAGGCCAAGGCGGGCGGATCACGAGGTCAAGAGATGGAGACTGTCCTGGCCAACATGG TGAAATCCCTTCTTTACTAAAAATACAAAAATTATCTGGGCGTGGTGGTGCATGCCTGTAGTCCCAGCTCCTTGGGAGGCTAAGGCAGGA GAATCACTTGAACCCGGGAGGCAGAGGTTGCAGTGAGCCGAGATTGCACCACTGCACTCCAGCCTGGCAACAGAGCAAGACTTCGTCTCA AAAAAAAAAAAAAAAAAAGTTTGAAAACCATTGGTATAGATAGATATTTTGAATTGATTTGCATAGTCTCCTTGAATGTGTTAAATTATG >69766_69766_9_PSMG2-PTPN2_PSMG2_chr18_12724618_ENST00000590217_PTPN2_chr18_12825943_ENST00000309660_length(amino acids)=329AA_BP=34 MKIRGQLTNLLFTVFSLKLTFQKGKSLVLHCTYYVKCAQYWPTDDQEMLFKETGFSVKLLSEDVKSYYTVHLLQLENINSGETRTISHFH YTTWPDFGVPESPASFLNFLFKVRESGSLNPDHGPAVIHCSAGIGRSGTFSLVDTCLVLMEKGDDINIKQVLLNMRKYRMGLIQTPDQLR FSYMAIIEGAKCIKGDSSIQKRWKELSKEDLSPAFDHSPNKIMTEKYNGNRIGLEEEKLTGDRCTGLSSKMQDTMEENSESALRKRIRED -------------------------------------------------------------- >69766_69766_10_PSMG2-PTPN2_PSMG2_chr18_12724618_ENST00000590217_PTPN2_chr18_12825943_ENST00000327283_length(transcript)=2064nt_BP=915nt TCCGGGGTCTCGGGCTTCCGCCTTCTTGCTGCCCTCGTTCTTGCCAGGGCCGCGGTTAGTCCCTGCTGGCCACCCCACTGCGACCATGTT CGTTCCCTGCGGGGAGTCGGCCCCCGACCTTGCCGGCTTCACCCTCCTAATGCCAGCAGTATCTGTTGGAAATGTTGGCCAGCTTGCAAT GGATCTGATTATTTCTACACTGAATATGTCTAAGATTGGTTACTTCTATACCGATTGTCTTGTGCCAATGGTTGGAAACAATCCATATGC GACCACAGAAGGAAATTCAACAGAACTTAGCATAAATGCTGAAGTGTATTCATTGCCTTCAAGAAAGCTGGTGGCTCTACAGTTAAGATC CATTTTTATTAAGTATAAATCAAAGCCATTCTGTGAAAAACTGCTTTCCTGGGTGAAAAGCAGTGGCTGTGCCAGAGTCATTGTTCTTTC AAGCAGTCATTCATATCAGCGTAATGATCTGCAGCTTCGTAGTACTCCCTTCCGGTACCTACTTACACCTTCCATGCAAAAAAGTGTTCA AAATAAAATAAAGAGCCTTAACTGGGAAGAAATGGAAAAAAGCCGGTGCATTCCTGAAATAGATGATTCCGAGTTTTGTATCCGCATTCC GGGAGGAGGTATCACAAAAACACTCTATGATGAAAGGTAAGTTCTATTATAGCTTAAGCCTCTTCTTTGTCTGGTTGTATTCATTAACTC GCACTTTATATACTACCTAAGTAGACCAAGTAAGTGAACGTTTGTATTAAATATAGACATATCTTTACATAAAATTTAGTTTAAGCTGAA CTTTTGAAAATTAGAGGACAGTTAACCAACCTATTATTTACAGTTTTTTCATTAAAGCTGACTTTCCAAAAAGGAAAATCCTTAGTTCTT CATTGTACTTACTATGTTAAATGTGCACAGTACTGGCCAACAGATGACCAAGAGATGCTGTTTAAAGAAACAGGATTCAGTGTGAAGCTC TTGTCAGAAGATGTGAAGTCGTATTATACAGTACATCTACTACAATTAGAAAATATCAATAGTGGTGAAACCAGAACAATATCTCACTTT CATTATACTACCTGGCCAGATTTTGGAGTCCCTGAATCACCAGCTTCATTTCTCAATTTCTTGTTTAAAGTGAGAGAATCTGGCTCCTTG AACCCTGACCATGGGCCTGCGGTGATCCACTGTAGTGCAGGCATTGGGCGCTCTGGCACCTTCTCTCTGGTAGACACTTGTCTTGTTTTG ATGGAAAAAGGAGATGATATTAACATAAAACAAGTGTTACTGAACATGAGAAAATACCGAATGGGTCTTATTCAGACCCCAGATCAACTG AGATTCTCATACATGGCTATAATAGAAGGAGCAAAATGTATAAAGGGAGATTCTAGTATACAGAAACGATGGAAAGAACTTTCTAAGGAA GACTTATCTCCTGCCTTTGATCATTCACCAAACAAAATAATGACTGAAAAATACAATGGGAACAGAATAGGTCTAGAAGAAGAAAAACTG ACAGGTGACCGATGTACAGGACTTTCCTCTAAAATGCAAGATACAATGGAGGAGAACAGTGAGAGTGCTCTACGGAAACGTATTCGAGAG GACAGAAAGGCCACCACAGCTCAGAAGGTGCAGCAGATGAAACAGAGGCTAAATGAGAATGAACGAAAAAGAAAAAGGCCAAGATTGACA GACACCTAATATTCATGACTTGAGAATATTCTGCAGCTATAAATTTTGAACCATTGATGTGCAAAGCAAGACCTGAAGCCCACTCCGGAA ACTAAAGTGAGGCTCGCTAACCCTCTAGATTGCCTCACAGTTGTTTGTTTACAAAGTAAACTTTACATCCAGGGGATGAAGAGCACCCAC CAGCAGAAGACTTTGCAGAACCTTTAATTGGATGTGTTAAGTGTTTTTAATGAGTGTATGAAATGTAGAAAGATGTACAAGAAATAAATT >69766_69766_10_PSMG2-PTPN2_PSMG2_chr18_12724618_ENST00000590217_PTPN2_chr18_12825943_ENST00000327283_length(amino acids)=301AA_BP=34 MKIRGQLTNLLFTVFSLKLTFQKGKSLVLHCTYYVKCAQYWPTDDQEMLFKETGFSVKLLSEDVKSYYTVHLLQLENINSGETRTISHFH YTTWPDFGVPESPASFLNFLFKVRESGSLNPDHGPAVIHCSAGIGRSGTFSLVDTCLVLMEKGDDINIKQVLLNMRKYRMGLIQTPDQLR FSYMAIIEGAKCIKGDSSIQKRWKELSKEDLSPAFDHSPNKIMTEKYNGNRIGLEEEKLTGDRCTGLSSKMQDTMEENSESALRKRIRED -------------------------------------------------------------- >69766_69766_11_PSMG2-PTPN2_PSMG2_chr18_12724618_ENST00000590217_PTPN2_chr18_12825943_ENST00000353319_length(transcript)=1957nt_BP=915nt TCCGGGGTCTCGGGCTTCCGCCTTCTTGCTGCCCTCGTTCTTGCCAGGGCCGCGGTTAGTCCCTGCTGGCCACCCCACTGCGACCATGTT CGTTCCCTGCGGGGAGTCGGCCCCCGACCTTGCCGGCTTCACCCTCCTAATGCCAGCAGTATCTGTTGGAAATGTTGGCCAGCTTGCAAT GGATCTGATTATTTCTACACTGAATATGTCTAAGATTGGTTACTTCTATACCGATTGTCTTGTGCCAATGGTTGGAAACAATCCATATGC GACCACAGAAGGAAATTCAACAGAACTTAGCATAAATGCTGAAGTGTATTCATTGCCTTCAAGAAAGCTGGTGGCTCTACAGTTAAGATC CATTTTTATTAAGTATAAATCAAAGCCATTCTGTGAAAAACTGCTTTCCTGGGTGAAAAGCAGTGGCTGTGCCAGAGTCATTGTTCTTTC AAGCAGTCATTCATATCAGCGTAATGATCTGCAGCTTCGTAGTACTCCCTTCCGGTACCTACTTACACCTTCCATGCAAAAAAGTGTTCA AAATAAAATAAAGAGCCTTAACTGGGAAGAAATGGAAAAAAGCCGGTGCATTCCTGAAATAGATGATTCCGAGTTTTGTATCCGCATTCC GGGAGGAGGTATCACAAAAACACTCTATGATGAAAGGTAAGTTCTATTATAGCTTAAGCCTCTTCTTTGTCTGGTTGTATTCATTAACTC GCACTTTATATACTACCTAAGTAGACCAAGTAAGTGAACGTTTGTATTAAATATAGACATATCTTTACATAAAATTTAGTTTAAGCTGAA CTTTTGAAAATTAGAGGACAGTTAACCAACCTATTATTTACAGTTTTTTCATTAAAGCTGACTTTCCAAAAAGGAAAATCCTTAGTTCTT CATTGTACTTACTATGTTAAATGTGCACAGTACTGGCCAACAGATGACCAAGAGATGCTGTTTAAAGAAACAGGATTCAGTGTGAAGCTC TTGTCAGAAGATGTGAAGTCGTATTATACAGTACATCTACTACAATTAGAAAATATCAATAGTGGTGAAACCAGAACAATATCTCACTTT CATTATACTACCTGGCCAGATTTTGGAGTCCCTGAATCACCAGCTTCATTTCTCAATTTCTTGTTTAAAGTGAGAGAATCTGGCTCCTTG AACCCTGACCATGGGCCTGCGGTGATCCACTGTAGTGCAGGCATTGGGCGCTCTGGCACCTTCTCTCTGGTAGACACTTGTCTTGTTTTG ATGGAAAAAGGAGATGATATTAACATAAAACAAGTGTTACTGAACATGAGAAAATACCGAATGGGTCTTATTCAGACCCCAGATCAACTG AGATTCTCATACATGGCTATAATAGAAGGAGCAAAATGTATAAAGGGAGATTCTAGTATACAGAAACGATGGAAAGAACTTTCTAAGGAA GACTTATCTCCTGCCTTTGATCATTCACCAAACAAAATAATGACTGAAAAATACAATGGGAACAGAATAGGTCTAGAAGAAGAAAAACTG ACAGGTGACCGATGTACAGGACTTTCCTCTAAAATGCAAGATACAATGGAGGAGAACAGTGAGAGGCCAAGATTGACAGACACCTAATAT TCATGACTTGAGAATATTCTGCAGCTATAAATTTTGAACCATTGATGTGCAAAGCAAGACCTGAAGCCCACTCCGGAAACTAAAGTGAGG CTCGCTAACCCTCTAGATTGCCTCACAGTTGTTTGTTTACAAAGTAAACTTTACATCCAGGGGATGAAGAGCACCCACCAGCAGAAGACT TTGCAGAACCTTTAATTGGATGTGTTAAGTGTTTTTAATGAGTGTATGAAATGTAGAAAGATGTACAAGAAATAAATTAGGGGAGATTAC >69766_69766_11_PSMG2-PTPN2_PSMG2_chr18_12724618_ENST00000590217_PTPN2_chr18_12825943_ENST00000353319_length(amino acids)=267AA_BP=34 MKIRGQLTNLLFTVFSLKLTFQKGKSLVLHCTYYVKCAQYWPTDDQEMLFKETGFSVKLLSEDVKSYYTVHLLQLENINSGETRTISHFH YTTWPDFGVPESPASFLNFLFKVRESGSLNPDHGPAVIHCSAGIGRSGTFSLVDTCLVLMEKGDDINIKQVLLNMRKYRMGLIQTPDQLR -------------------------------------------------------------- >69766_69766_12_PSMG2-PTPN2_PSMG2_chr18_12724618_ENST00000590217_PTPN2_chr18_12825943_ENST00000591115_length(transcript)=2130nt_BP=915nt TCCGGGGTCTCGGGCTTCCGCCTTCTTGCTGCCCTCGTTCTTGCCAGGGCCGCGGTTAGTCCCTGCTGGCCACCCCACTGCGACCATGTT CGTTCCCTGCGGGGAGTCGGCCCCCGACCTTGCCGGCTTCACCCTCCTAATGCCAGCAGTATCTGTTGGAAATGTTGGCCAGCTTGCAAT GGATCTGATTATTTCTACACTGAATATGTCTAAGATTGGTTACTTCTATACCGATTGTCTTGTGCCAATGGTTGGAAACAATCCATATGC GACCACAGAAGGAAATTCAACAGAACTTAGCATAAATGCTGAAGTGTATTCATTGCCTTCAAGAAAGCTGGTGGCTCTACAGTTAAGATC CATTTTTATTAAGTATAAATCAAAGCCATTCTGTGAAAAACTGCTTTCCTGGGTGAAAAGCAGTGGCTGTGCCAGAGTCATTGTTCTTTC AAGCAGTCATTCATATCAGCGTAATGATCTGCAGCTTCGTAGTACTCCCTTCCGGTACCTACTTACACCTTCCATGCAAAAAAGTGTTCA AAATAAAATAAAGAGCCTTAACTGGGAAGAAATGGAAAAAAGCCGGTGCATTCCTGAAATAGATGATTCCGAGTTTTGTATCCGCATTCC GGGAGGAGGTATCACAAAAACACTCTATGATGAAAGGTAAGTTCTATTATAGCTTAAGCCTCTTCTTTGTCTGGTTGTATTCATTAACTC GCACTTTATATACTACCTAAGTAGACCAAGTAAGTGAACGTTTGTATTAAATATAGACATATCTTTACATAAAATTTAGTTTAAGCTGAA CTTTTGAAAATTAGAGGACAGTTAACCAACCTATTATTTACAGTTTTTTCATTAAAGCTGACTTTCCAAAAAGGAAAATCCTTAGTTCTT CATTGTACTTACTATGTTAAATGTGCACAGTACTGGCCAACAGATGACCAAGAGATGCTGTTTAAAGAAACAGGATTCAGTGTGAAGCTC TTGTCAGAAGATGTGAAGTCGTATTATACAGTACATCTACTACAATTAGAAAATATCAATTATATTGAGAACTTGTGGATCACACTGTAT TTGAAATTATTAATGCTGGATGTTAAAAGGTCACTAAAAAGTGGTGAAACCAGAACAATATCTCACTTTCATTATACTACCTGGCCAGAT TTTGGAGTCCCTGAATCACCAGCTTCATTTCTCAATTTCTTGTTTAAAGTGAGAGAATCTGGCTCCTTGAACCCTGACCATGGGCCTGCG GTGATCCACTGTAGTGCAGGCATTGGGCGCTCTGGCACCTTCTCTCTGGTAGACACTTGTCTTGTTTTGATGGAAAAAGGAGATGATATT AACATAAAACAAGTGTTACTGAACATGAGAAAATACCGAATGGGTCTTATTCAGACCCCAGATCAACTGAGATTCTCATACATGGCTATA ATAGAAGGAGCAAAATGTATAAAGGGAGATTCTAGTATACAGAAACGATGGAAAGAACTTTCTAAGGAAGACTTATCTCCTGCCTTTGAT CATTCACCAAACAAAATAATGACTGAAAAATACAATGGGAACAGAATAGGTCTAGAAGAAGAAAAACTGACAGGTGACCGATGTACAGGA CTTTCCTCTAAAATGCAAGATACAATGGAGGAGAACAGTGAGAGTGCTCTACGGAAACGTATTCGAGAGGACAGAAAGGCCACCACAGCT CAGAAGGTGCAGCAGATGAAACAGAGGCTAAATGAGAATGAACGAAAAAGAAAAAGGCCAAGATTGACAGACACCTAATATTCATGACTT GAGAATATTCTGCAGCTATAAATTTTGAACCATTGATGTGCAAAGCAAGACCTGAAGCCCACTCCGGAAACTAAAGTGAGGCTCGCTAAC CCTCTAGATTGCCTCACAGTTGTTTGTTTACAAAGTAAACTTTACATCCAGGGGATGAAGAGCACCCACCAGCAGAAGACTTTGCAGAAC CTTTAATTGGATGTGTTAAGTGTTTTTAATGAGTGTATGAAATGTAGAAAGATGTACAAGAAATAAATTAGGGGAGATTACTTTGTATTG >69766_69766_12_PSMG2-PTPN2_PSMG2_chr18_12724618_ENST00000590217_PTPN2_chr18_12825943_ENST00000591115_length(amino acids)=324AA_BP=34 MKIRGQLTNLLFTVFSLKLTFQKGKSLVLHCTYYVKCAQYWPTDDQEMLFKETGFSVKLLSEDVKSYYTVHLLQLENINYIENLWITLYL KLLMLDVKRSLKSGETRTISHFHYTTWPDFGVPESPASFLNFLFKVRESGSLNPDHGPAVIHCSAGIGRSGTFSLVDTCLVLMEKGDDIN IKQVLLNMRKYRMGLIQTPDQLRFSYMAIIEGAKCIKGDSSIQKRWKELSKEDLSPAFDHSPNKIMTEKYNGNRIGLEEEKLTGDRCTGL -------------------------------------------------------------- |
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Fusion Gene PPI Analysis for PSMG2-PTPN2 |
| Go to ChiPPI (Chimeric Protein-Protein interactions) to see the chimeric PPI interaction in |
| Protein-protein interactors with each fusion partner protein in wild-type (BIOGRID-3.4.160) |
| Hgene | Hgene's interactors | Tgene | Tgene's interactors |
| - Retained PPIs in in-frame fusion. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Still interaction with |
| - Lost PPIs in in-frame fusion. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Interaction lost with |
| - Retained PPIs, but lost function due to frame-shift fusion. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Interaction lost with |
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Related Drugs for PSMG2-PTPN2 |
| Drugs targeting genes involved in this fusion gene. (DrugBank Version 5.1.8 2021-05-08) |
| Partner | Gene | UniProtAcc | DrugBank ID | Drug name | Drug activity | Drug type | Drug status |
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Related Diseases for PSMG2-PTPN2 |
| Diseases associated with fusion partners. (DisGeNet 4.0) |
| Partner | Gene | Disease ID | Disease name | # pubmeds | Source |
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