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Center for Computational Systems Medicine
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Fusion Gene Summary

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Fusion Gene ORF analysis

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Fusion Genomic Features

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Fusion Protein Features

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Fusion Gene Sequence

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Fusion Gene PPI analysis

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Related Drugs

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Related Diseases

Fusion gene:PTPN12-DYNC1I1 (FusionGDB2 ID:70191)

Fusion Gene Summary for PTPN12-DYNC1I1

check button Fusion gene summary
Fusion gene informationFusion gene name: PTPN12-DYNC1I1
Fusion gene ID: 70191
HgeneTgene
Gene symbol

PTPN12

DYNC1I1

Gene ID

5782

1780

Gene nameprotein tyrosine phosphatase non-receptor type 12dynein cytoplasmic 1 intermediate chain 1
SynonymsPTP-PEST|PTPG1DNCI1|DNCIC1
Cytomap

7q11.23

7q21.3

Type of geneprotein-codingprotein-coding
Descriptiontyrosine-protein phosphatase non-receptor type 12protein-tyrosine phosphatase G1cytoplasmic dynein 1 intermediate chain 1DH IC-1cytoplasmic dynein intermediate chain 1dynein intermediate chain 1, cytosolicdynein, cytoplasmic, intermediate polypeptide 1
Modification date2020032920200313
UniProtAcc.

O14576

Ensembl transtripts involved in fusion geneENST00000248594, ENST00000415482, 
ENST00000435495, 		ENST00000413338, 
ENST00000457059, ENST00000497626, 
ENST00000324972, ENST00000359388, 
ENST00000437599, ENST00000447467, 
ENST00000537881, 
Fusion gene scores* DoF score22 X 21 X 16=739212 X 12 X 6=864
# samples 4413
** MAII scorelog2(44/7392*10)=-4.0703893278914
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0		log2(13/864*10)=-2.73251968913501
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0
Context

PubMed: PTPN12 [Title/Abstract] AND DYNC1I1 [Title/Abstract] AND fusion [Title/Abstract]

Most frequent breakpointPTPN12(77166962)-DYNC1I1(95705369), # samples:3
Anticipated loss of major functional domain due to fusion event.
* DoF score (Degree of Frequency) = # partners X # break points X # cancer types
** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10)

check button Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez
PartnerGeneGO IDGO termPubMed ID
HgenePTPN12

GO:0006470

protein dephosphorylation

27134172

HgenePTPN12

GO:0035335

peptidyl-tyrosine dephosphorylation

27134172


check buttonFusion gene breakpoints across PTPN12 (5'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.
all structure

check buttonFusion gene breakpoints across DYNC1I1 (3'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.
all structure

check button Fusion gene information from two resources (ChiTars 5.0 and ChimerDB 4.0)
* All genome coordinats were lifted-over on hg19.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
SourceDiseaseSampleHgeneHchrHbpHstrandTgeneTchrTbpTstrand
ChimerDB4LGGTCGA-DU-5855-01APTPN12chr7

77166961

+DYNC1I1chr7

95705368

+
ChimerDB4LGGTCGA-DU-5855-01APTPN12chr7

77166962

-DYNC1I1chr7

95705369

+
ChimerDB4LGGTCGA-DU-5855-01APTPN12chr7

77166962

+DYNC1I1chr7

95705369

+
ChimerDB4LGGTCGA-DU-5855PTPN12chr7

77166962

+DYNC1I1chr7

95705368

+
ChimerDB4LGGTCGA-DU-5855PTPN12chr7

77166962

+DYNC1I1chr7

95705369

+


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Fusion Gene ORF analysis for PTPN12-DYNC1I1

check button Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
ORFHenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrand
5CDS-intronENST00000248594ENST00000413338PTPN12chr7

77166961

+DYNC1I1chr7

95705368

+
5CDS-intronENST00000248594ENST00000413338PTPN12chr7

77166962

+DYNC1I1chr7

95705369

+
5CDS-intronENST00000248594ENST00000413338PTPN12chr7

77166962

+DYNC1I1chr7

95705368

+
5CDS-intronENST00000248594ENST00000457059PTPN12chr7

77166961

+DYNC1I1chr7

95705368

+
5CDS-intronENST00000248594ENST00000457059PTPN12chr7

77166962

+DYNC1I1chr7

95705369

+
5CDS-intronENST00000248594ENST00000457059PTPN12chr7

77166962

+DYNC1I1chr7

95705368

+
5CDS-intronENST00000248594ENST00000497626PTPN12chr7

77166961

+DYNC1I1chr7

95705368

+
5CDS-intronENST00000248594ENST00000497626PTPN12chr7

77166962

+DYNC1I1chr7

95705369

+
5CDS-intronENST00000248594ENST00000497626PTPN12chr7

77166962

+DYNC1I1chr7

95705368

+
In-frameENST00000248594ENST00000324972PTPN12chr7

77166961

+DYNC1I1chr7

95705368

+
In-frameENST00000248594ENST00000324972PTPN12chr7

77166962

+DYNC1I1chr7

95705369

+
In-frameENST00000248594ENST00000324972PTPN12chr7

77166962

+DYNC1I1chr7

95705368

+
In-frameENST00000248594ENST00000359388PTPN12chr7

77166961

+DYNC1I1chr7

95705368

+
In-frameENST00000248594ENST00000359388PTPN12chr7

77166962

+DYNC1I1chr7

95705369

+
In-frameENST00000248594ENST00000359388PTPN12chr7

77166962

+DYNC1I1chr7

95705368

+
In-frameENST00000248594ENST00000437599PTPN12chr7

77166961

+DYNC1I1chr7

95705368

+
In-frameENST00000248594ENST00000437599PTPN12chr7

77166962

+DYNC1I1chr7

95705369

+
In-frameENST00000248594ENST00000437599PTPN12chr7

77166962

+DYNC1I1chr7

95705368

+
In-frameENST00000248594ENST00000447467PTPN12chr7

77166961

+DYNC1I1chr7

95705368

+
In-frameENST00000248594ENST00000447467PTPN12chr7

77166962

+DYNC1I1chr7

95705369

+
In-frameENST00000248594ENST00000447467PTPN12chr7

77166962

+DYNC1I1chr7

95705368

+
In-frameENST00000248594ENST00000537881PTPN12chr7

77166961

+DYNC1I1chr7

95705368

+
In-frameENST00000248594ENST00000537881PTPN12chr7

77166962

+DYNC1I1chr7

95705369

+
In-frameENST00000248594ENST00000537881PTPN12chr7

77166962

+DYNC1I1chr7

95705368

+
intron-3CDSENST00000415482ENST00000324972PTPN12chr7

77166961

+DYNC1I1chr7

95705368

+
intron-3CDSENST00000415482ENST00000324972PTPN12chr7

77166962

+DYNC1I1chr7

95705369

+
intron-3CDSENST00000415482ENST00000324972PTPN12chr7

77166962

+DYNC1I1chr7

95705368

+
intron-3CDSENST00000415482ENST00000359388PTPN12chr7

77166961

+DYNC1I1chr7

95705368

+
intron-3CDSENST00000415482ENST00000359388PTPN12chr7

77166962

+DYNC1I1chr7

95705369

+
intron-3CDSENST00000415482ENST00000359388PTPN12chr7

77166962

+DYNC1I1chr7

95705368

+
intron-3CDSENST00000415482ENST00000437599PTPN12chr7

77166961

+DYNC1I1chr7

95705368

+
intron-3CDSENST00000415482ENST00000437599PTPN12chr7

77166962

+DYNC1I1chr7

95705369

+
intron-3CDSENST00000415482ENST00000437599PTPN12chr7

77166962

+DYNC1I1chr7

95705368

+
intron-3CDSENST00000415482ENST00000447467PTPN12chr7

77166961

+DYNC1I1chr7

95705368

+
intron-3CDSENST00000415482ENST00000447467PTPN12chr7

77166962

+DYNC1I1chr7

95705369

+
intron-3CDSENST00000415482ENST00000447467PTPN12chr7

77166962

+DYNC1I1chr7

95705368

+
intron-3CDSENST00000415482ENST00000537881PTPN12chr7

77166961

+DYNC1I1chr7

95705368

+
intron-3CDSENST00000415482ENST00000537881PTPN12chr7

77166962

+DYNC1I1chr7

95705369

+
intron-3CDSENST00000415482ENST00000537881PTPN12chr7

77166962

+DYNC1I1chr7

95705368

+
intron-3CDSENST00000435495ENST00000324972PTPN12chr7

77166961

+DYNC1I1chr7

95705368

+
intron-3CDSENST00000435495ENST00000324972PTPN12chr7

77166962

+DYNC1I1chr7

95705369

+
intron-3CDSENST00000435495ENST00000324972PTPN12chr7

77166962

+DYNC1I1chr7

95705368

+
intron-3CDSENST00000435495ENST00000359388PTPN12chr7

77166961

+DYNC1I1chr7

95705368

+
intron-3CDSENST00000435495ENST00000359388PTPN12chr7

77166962

+DYNC1I1chr7

95705369

+
intron-3CDSENST00000435495ENST00000359388PTPN12chr7

77166962

+DYNC1I1chr7

95705368

+
intron-3CDSENST00000435495ENST00000437599PTPN12chr7

77166961

+DYNC1I1chr7

95705368

+
intron-3CDSENST00000435495ENST00000437599PTPN12chr7

77166962

+DYNC1I1chr7

95705369

+
intron-3CDSENST00000435495ENST00000437599PTPN12chr7

77166962

+DYNC1I1chr7

95705368

+
intron-3CDSENST00000435495ENST00000447467PTPN12chr7

77166961

+DYNC1I1chr7

95705368

+
intron-3CDSENST00000435495ENST00000447467PTPN12chr7

77166962

+DYNC1I1chr7

95705369

+
intron-3CDSENST00000435495ENST00000447467PTPN12chr7

77166962

+DYNC1I1chr7

95705368

+
intron-3CDSENST00000435495ENST00000537881PTPN12chr7

77166961

+DYNC1I1chr7

95705368

+
intron-3CDSENST00000435495ENST00000537881PTPN12chr7

77166962

+DYNC1I1chr7

95705369

+
intron-3CDSENST00000435495ENST00000537881PTPN12chr7

77166962

+DYNC1I1chr7

95705368

+
intron-intronENST00000415482ENST00000413338PTPN12chr7

77166961

+DYNC1I1chr7

95705368

+
intron-intronENST00000415482ENST00000413338PTPN12chr7

77166962

+DYNC1I1chr7

95705369

+
intron-intronENST00000415482ENST00000413338PTPN12chr7

77166962

+DYNC1I1chr7

95705368

+
intron-intronENST00000415482ENST00000457059PTPN12chr7

77166961

+DYNC1I1chr7

95705368

+
intron-intronENST00000415482ENST00000457059PTPN12chr7

77166962

+DYNC1I1chr7

95705369

+
intron-intronENST00000415482ENST00000457059PTPN12chr7

77166962

+DYNC1I1chr7

95705368

+
intron-intronENST00000415482ENST00000497626PTPN12chr7

77166961

+DYNC1I1chr7

95705368

+
intron-intronENST00000415482ENST00000497626PTPN12chr7

77166962

+DYNC1I1chr7

95705369

+
intron-intronENST00000415482ENST00000497626PTPN12chr7

77166962

+DYNC1I1chr7

95705368

+
intron-intronENST00000435495ENST00000413338PTPN12chr7

77166961

+DYNC1I1chr7

95705368

+
intron-intronENST00000435495ENST00000413338PTPN12chr7

77166962

+DYNC1I1chr7

95705369

+
intron-intronENST00000435495ENST00000413338PTPN12chr7

77166962

+DYNC1I1chr7

95705368

+
intron-intronENST00000435495ENST00000457059PTPN12chr7

77166961

+DYNC1I1chr7

95705368

+
intron-intronENST00000435495ENST00000457059PTPN12chr7

77166962

+DYNC1I1chr7

95705369

+
intron-intronENST00000435495ENST00000457059PTPN12chr7

77166962

+DYNC1I1chr7

95705368

+
intron-intronENST00000435495ENST00000497626PTPN12chr7

77166961

+DYNC1I1chr7

95705368

+
intron-intronENST00000435495ENST00000497626PTPN12chr7

77166962

+DYNC1I1chr7

95705369

+
intron-intronENST00000435495ENST00000497626PTPN12chr7

77166962

+DYNC1I1chr7

95705368

+

check buttonORFfinder result based on the fusion transcript sequence of in-frame fusion genes.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandSeq length
(transcript)		BP loci
(transcript)		Predicted start
(transcript)		Predicted stop
(transcript)		Seq length
(amino acids)
ENST00000248594PTPN12chr777166962+ENST00000447467DYNC1I1chr795705369+15803712748248
ENST00000248594PTPN12chr777166962+ENST00000324972DYNC1I1chr795705369+15683712748248
ENST00000248594PTPN12chr777166962+ENST00000537881DYNC1I1chr795705369+9823712730242
ENST00000248594PTPN12chr777166962+ENST00000437599DYNC1I1chr795705369+15803712748248
ENST00000248594PTPN12chr777166962+ENST00000359388DYNC1I1chr795705369+15803712748248
ENST00000248594PTPN12chr777166962+ENST00000447467DYNC1I1chr795705368+15803712748248
ENST00000248594PTPN12chr777166962+ENST00000324972DYNC1I1chr795705368+15683712748248
ENST00000248594PTPN12chr777166962+ENST00000537881DYNC1I1chr795705368+9823712730242
ENST00000248594PTPN12chr777166962+ENST00000437599DYNC1I1chr795705368+15803712748248
ENST00000248594PTPN12chr777166962+ENST00000359388DYNC1I1chr795705368+15803712748248
ENST00000248594PTPN12chr777166961+ENST00000447467DYNC1I1chr795705368+15803712748248
ENST00000248594PTPN12chr777166961+ENST00000324972DYNC1I1chr795705368+15683712748248
ENST00000248594PTPN12chr777166961+ENST00000537881DYNC1I1chr795705368+9823712730242
ENST00000248594PTPN12chr777166961+ENST00000437599DYNC1I1chr795705368+15803712748248
ENST00000248594PTPN12chr777166961+ENST00000359388DYNC1I1chr795705368+15803712748248

check buttonDeepORF prediction of the coding potential based on the fusion transcript sequence of in-frame fusion genes. DeepORF is a coding potential classifier based on convolutional neural network by comparing the real Ribo-seq data. If the no-coding score < 0.5 and coding score > 0.5, then the in-frame fusion transcript is predicted as being likely translated.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandNo-coding scoreCoding score
ENST00000248594ENST00000447467PTPN12chr777166962+DYNC1I1chr795705369+0.089472040.910528
ENST00000248594ENST00000324972PTPN12chr777166962+DYNC1I1chr795705369+0.0906624640.9093376
ENST00000248594ENST00000537881PTPN12chr777166962+DYNC1I1chr795705369+0.0061040450.99389595
ENST00000248594ENST00000437599PTPN12chr777166962+DYNC1I1chr795705369+0.089472040.910528
ENST00000248594ENST00000359388PTPN12chr777166962+DYNC1I1chr795705369+0.089472040.910528
ENST00000248594ENST00000447467PTPN12chr777166962+DYNC1I1chr795705368+0.089472040.910528
ENST00000248594ENST00000324972PTPN12chr777166962+DYNC1I1chr795705368+0.0906624640.9093376
ENST00000248594ENST00000537881PTPN12chr777166962+DYNC1I1chr795705368+0.0061040450.99389595
ENST00000248594ENST00000437599PTPN12chr777166962+DYNC1I1chr795705368+0.089472040.910528
ENST00000248594ENST00000359388PTPN12chr777166962+DYNC1I1chr795705368+0.089472040.910528
ENST00000248594ENST00000447467PTPN12chr777166961+DYNC1I1chr795705368+0.089472040.910528
ENST00000248594ENST00000324972PTPN12chr777166961+DYNC1I1chr795705368+0.0906624640.9093376
ENST00000248594ENST00000537881PTPN12chr777166961+DYNC1I1chr795705368+0.0061040450.99389595
ENST00000248594ENST00000437599PTPN12chr777166961+DYNC1I1chr795705368+0.089472040.910528
ENST00000248594ENST00000359388PTPN12chr777166961+DYNC1I1chr795705368+0.089472040.910528

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Fusion Genomic Features for PTPN12-DYNC1I1


check buttonFusionAI prediction of the potential fusion gene breakpoint based on the pre-mature RNA sequence context (+/- 5kb of individual partner genes, total 20kb length sequence). FusionAI is a fusion gene breakpoint classifier based on convolutional neural network by comparing the fusion positive and negative sequence context of ~ 20K fusion gene data. From here, we can have the relative potentency of the 20K genomic sequence how individual sequnce will be likely used as the gene fusion breakpoints.
HgeneHchrHbpHstrandTgeneTchrTbpTstrand1-pp (fusion gene breakpoint)
PTPN12chr777166962+DYNC1I1chr795705368+6.21E-091
PTPN12chr777166962+DYNC1I1chr795705368+6.21E-091
PTPN12chr777166962+DYNC1I1chr795705368+6.21E-091
PTPN12chr777166962+DYNC1I1chr795705368+6.21E-091

check buttonDistribution of 44 human genomic features loci across 20kb length fusion breakpoint regions. We integrated a total of 44 different types of human genomic feature loci information across five big categories including virus integration sites, repeats, structural variants, chromatin states, and gene expression regulation. More details are in help page.
genomic feature

check buttonDistribution of 44 human genomic features loci across 20kb length fusion breakpoint regions that are ovelapped with the top 1% feature importance score regions. More details are in help page.
genomic feature of top 1%

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Fusion Protein Features for PTPN12-DYNC1I1


check button Four levels of functional features of fusion genes
Go to FGviewer search page for the most frequent breakpoint (https://ccsmweb.uth.edu/FGviewer/chr7:77166962/chr7:95705369)
- FGviewer provides the online visualization of the retention search of the protein functional features across DNA, RNA, protein, and pathological levels.
- How to search
1. Put your fusion gene symbol.
2. Press the tab key until there will be shown the breakpoint information filled.
4. Go down and press 'Search' tab twice.
4. Go down to have the hyperlink of the search result.
5. Click the hyperlink.
6. See the FGviewer result for your fusion gene.
FGviewer

check buttonMain function of each fusion partner protein. (from UniProt)
HgeneTgene
.DYNC1I1

O14576

FUNCTION: Transcriptional activator which is required for calcium-dependent dendritic growth and branching in cortical neurons. Recruits CREB-binding protein (CREBBP) to nuclear bodies. Component of the CREST-BRG1 complex, a multiprotein complex that regulates promoter activation by orchestrating a calcium-dependent release of a repressor complex and a recruitment of an activator complex. In resting neurons, transcription of the c-FOS promoter is inhibited by BRG1-dependent recruitment of a phospho-RB1-HDAC1 repressor complex. Upon calcium influx, RB1 is dephosphorylated by calcineurin, which leads to release of the repressor complex. At the same time, there is increased recruitment of CREBBP to the promoter by a CREST-dependent mechanism, which leads to transcriptional activation. The CREST-BRG1 complex also binds to the NR2B promoter, and activity-dependent induction of NR2B expression involves a release of HDAC1 and recruitment of CREBBP (By similarity). {ECO:0000250}.FUNCTION: Acts as one of several non-catalytic accessory components of the cytoplasmic dynein 1 complex that are thought to be involved in linking dynein to cargos and to adapter proteins that regulate dynein function. Cytoplasmic dynein 1 acts as a motor for the intracellular retrograde motility of vesicles and organelles along microtubules. The intermediate chains mediate the binding of dynein to dynactin via its 150 kDa component (p150-glued) DCTN1. May play a role in mediating the interaction of cytoplasmic dynein with membranous organelles and kinetochores.

check buttonRetention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at

download page


* Minus value of BPloci means that the break pointn is located before the CDS.
- In-frame and retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
TgeneDYNC1I1chr7:77166961chr7:95705368ENST000003249721317530_570520646.0RepeatNote=WD 6
TgeneDYNC1I1chr7:77166961chr7:95705368ENST000003249721317576_615520646.0RepeatNote=WD 7
TgeneDYNC1I1chr7:77166961chr7:95705368ENST000003593881216482_527483609.0RepeatNote=WD 5
TgeneDYNC1I1chr7:77166961chr7:95705368ENST000003593881216530_570483609.0RepeatNote=WD 6
TgeneDYNC1I1chr7:77166961chr7:95705368ENST000003593881216576_615483609.0RepeatNote=WD 7
TgeneDYNC1I1chr7:77166961chr7:95705368ENST000004474671317530_570503629.0RepeatNote=WD 6
TgeneDYNC1I1chr7:77166961chr7:95705368ENST000004474671317576_615503629.0RepeatNote=WD 7
TgeneDYNC1I1chr7:77166961chr7:95705368ENST000004570591317530_570503629.0RepeatNote=WD 6
TgeneDYNC1I1chr7:77166961chr7:95705368ENST000004570591317576_615503629.0RepeatNote=WD 7
TgeneDYNC1I1chr7:77166962chr7:95705368ENST000003249721317530_570520646.0RepeatNote=WD 6
TgeneDYNC1I1chr7:77166962chr7:95705368ENST000003249721317576_615520646.0RepeatNote=WD 7
TgeneDYNC1I1chr7:77166962chr7:95705368ENST000003593881216482_527483609.0RepeatNote=WD 5
TgeneDYNC1I1chr7:77166962chr7:95705368ENST000003593881216530_570483609.0RepeatNote=WD 6
TgeneDYNC1I1chr7:77166962chr7:95705368ENST000003593881216576_615483609.0RepeatNote=WD 7
TgeneDYNC1I1chr7:77166962chr7:95705368ENST000004474671317530_570503629.0RepeatNote=WD 6
TgeneDYNC1I1chr7:77166962chr7:95705368ENST000004474671317576_615503629.0RepeatNote=WD 7
TgeneDYNC1I1chr7:77166962chr7:95705368ENST000004570591317530_570503629.0RepeatNote=WD 6
TgeneDYNC1I1chr7:77166962chr7:95705368ENST000004570591317576_615503629.0RepeatNote=WD 7
TgeneDYNC1I1chr7:77166962chr7:95705369ENST000003249721317530_570520646.0RepeatNote=WD 6
TgeneDYNC1I1chr7:77166962chr7:95705369ENST000003249721317576_615520646.0RepeatNote=WD 7
TgeneDYNC1I1chr7:77166962chr7:95705369ENST000003593881216482_527483609.0RepeatNote=WD 5
TgeneDYNC1I1chr7:77166962chr7:95705369ENST000003593881216530_570483609.0RepeatNote=WD 6
TgeneDYNC1I1chr7:77166962chr7:95705369ENST000003593881216576_615483609.0RepeatNote=WD 7
TgeneDYNC1I1chr7:77166962chr7:95705369ENST000004474671317530_570503629.0RepeatNote=WD 6
TgeneDYNC1I1chr7:77166962chr7:95705369ENST000004474671317576_615503629.0RepeatNote=WD 7
TgeneDYNC1I1chr7:77166962chr7:95705369ENST000004570591317530_570503629.0RepeatNote=WD 6
TgeneDYNC1I1chr7:77166962chr7:95705369ENST000004570591317576_615503629.0RepeatNote=WD 7

- In-frame and not-retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
HgenePTPN12chr7:77166961chr7:95705368ENST00000248594+11828_29333781.0DomainTyrosine-protein phosphatase
HgenePTPN12chr7:77166961chr7:95705368ENST00000435495+11728_2930651.0DomainTyrosine-protein phosphatase
HgenePTPN12chr7:77166962chr7:95705368ENST00000248594+11828_29333781.0DomainTyrosine-protein phosphatase
HgenePTPN12chr7:77166962chr7:95705368ENST00000435495+11728_2930651.0DomainTyrosine-protein phosphatase
HgenePTPN12chr7:77166962chr7:95705369ENST00000248594+11828_29333781.0DomainTyrosine-protein phosphatase
HgenePTPN12chr7:77166962chr7:95705369ENST00000435495+11728_2930651.0DomainTyrosine-protein phosphatase
HgenePTPN12chr7:77166961chr7:95705368ENST00000248594+118231_23733781.0RegionSubstrate binding
HgenePTPN12chr7:77166961chr7:95705368ENST00000248594+11863_6733781.0RegionSubstrate binding
HgenePTPN12chr7:77166961chr7:95705368ENST00000435495+117231_2370651.0RegionSubstrate binding
HgenePTPN12chr7:77166961chr7:95705368ENST00000435495+11763_670651.0RegionSubstrate binding
HgenePTPN12chr7:77166962chr7:95705368ENST00000248594+118231_23733781.0RegionSubstrate binding
HgenePTPN12chr7:77166962chr7:95705368ENST00000248594+11863_6733781.0RegionSubstrate binding
HgenePTPN12chr7:77166962chr7:95705368ENST00000435495+117231_2370651.0RegionSubstrate binding
HgenePTPN12chr7:77166962chr7:95705368ENST00000435495+11763_670651.0RegionSubstrate binding
HgenePTPN12chr7:77166962chr7:95705369ENST00000248594+118231_23733781.0RegionSubstrate binding
HgenePTPN12chr7:77166962chr7:95705369ENST00000248594+11863_6733781.0RegionSubstrate binding
HgenePTPN12chr7:77166962chr7:95705369ENST00000435495+117231_2370651.0RegionSubstrate binding
HgenePTPN12chr7:77166962chr7:95705369ENST00000435495+11763_670651.0RegionSubstrate binding
TgeneDYNC1I1chr7:77166961chr7:95705368ENST000003249721317285_334520646.0RepeatNote=WD 1
TgeneDYNC1I1chr7:77166961chr7:95705368ENST000003249721317338_378520646.0RepeatNote=WD 2
TgeneDYNC1I1chr7:77166961chr7:95705368ENST000003249721317387_428520646.0RepeatNote=WD 3
TgeneDYNC1I1chr7:77166961chr7:95705368ENST000003249721317437_477520646.0RepeatNote=WD 4
TgeneDYNC1I1chr7:77166961chr7:95705368ENST000003249721317482_527520646.0RepeatNote=WD 5
TgeneDYNC1I1chr7:77166961chr7:95705368ENST000003593881216285_334483609.0RepeatNote=WD 1
TgeneDYNC1I1chr7:77166961chr7:95705368ENST000003593881216338_378483609.0RepeatNote=WD 2
TgeneDYNC1I1chr7:77166961chr7:95705368ENST000003593881216387_428483609.0RepeatNote=WD 3
TgeneDYNC1I1chr7:77166961chr7:95705368ENST000003593881216437_477483609.0RepeatNote=WD 4
TgeneDYNC1I1chr7:77166961chr7:95705368ENST000004474671317285_334503629.0RepeatNote=WD 1
TgeneDYNC1I1chr7:77166961chr7:95705368ENST000004474671317338_378503629.0RepeatNote=WD 2
TgeneDYNC1I1chr7:77166961chr7:95705368ENST000004474671317387_428503629.0RepeatNote=WD 3
TgeneDYNC1I1chr7:77166961chr7:95705368ENST000004474671317437_477503629.0RepeatNote=WD 4
TgeneDYNC1I1chr7:77166961chr7:95705368ENST000004474671317482_527503629.0RepeatNote=WD 5
TgeneDYNC1I1chr7:77166961chr7:95705368ENST000004570591317285_334503629.0RepeatNote=WD 1
TgeneDYNC1I1chr7:77166961chr7:95705368ENST000004570591317338_378503629.0RepeatNote=WD 2
TgeneDYNC1I1chr7:77166961chr7:95705368ENST000004570591317387_428503629.0RepeatNote=WD 3
TgeneDYNC1I1chr7:77166961chr7:95705368ENST000004570591317437_477503629.0RepeatNote=WD 4
TgeneDYNC1I1chr7:77166961chr7:95705368ENST000004570591317482_527503629.0RepeatNote=WD 5
TgeneDYNC1I1chr7:77166962chr7:95705368ENST000003249721317285_334520646.0RepeatNote=WD 1
TgeneDYNC1I1chr7:77166962chr7:95705368ENST000003249721317338_378520646.0RepeatNote=WD 2
TgeneDYNC1I1chr7:77166962chr7:95705368ENST000003249721317387_428520646.0RepeatNote=WD 3
TgeneDYNC1I1chr7:77166962chr7:95705368ENST000003249721317437_477520646.0RepeatNote=WD 4
TgeneDYNC1I1chr7:77166962chr7:95705368ENST000003249721317482_527520646.0RepeatNote=WD 5
TgeneDYNC1I1chr7:77166962chr7:95705368ENST000003593881216285_334483609.0RepeatNote=WD 1
TgeneDYNC1I1chr7:77166962chr7:95705368ENST000003593881216338_378483609.0RepeatNote=WD 2
TgeneDYNC1I1chr7:77166962chr7:95705368ENST000003593881216387_428483609.0RepeatNote=WD 3
TgeneDYNC1I1chr7:77166962chr7:95705368ENST000003593881216437_477483609.0RepeatNote=WD 4
TgeneDYNC1I1chr7:77166962chr7:95705368ENST000004474671317285_334503629.0RepeatNote=WD 1
TgeneDYNC1I1chr7:77166962chr7:95705368ENST000004474671317338_378503629.0RepeatNote=WD 2
TgeneDYNC1I1chr7:77166962chr7:95705368ENST000004474671317387_428503629.0RepeatNote=WD 3
TgeneDYNC1I1chr7:77166962chr7:95705368ENST000004474671317437_477503629.0RepeatNote=WD 4
TgeneDYNC1I1chr7:77166962chr7:95705368ENST000004474671317482_527503629.0RepeatNote=WD 5
TgeneDYNC1I1chr7:77166962chr7:95705368ENST000004570591317285_334503629.0RepeatNote=WD 1
TgeneDYNC1I1chr7:77166962chr7:95705368ENST000004570591317338_378503629.0RepeatNote=WD 2
TgeneDYNC1I1chr7:77166962chr7:95705368ENST000004570591317387_428503629.0RepeatNote=WD 3
TgeneDYNC1I1chr7:77166962chr7:95705368ENST000004570591317437_477503629.0RepeatNote=WD 4
TgeneDYNC1I1chr7:77166962chr7:95705368ENST000004570591317482_527503629.0RepeatNote=WD 5
TgeneDYNC1I1chr7:77166962chr7:95705369ENST000003249721317285_334520646.0RepeatNote=WD 1
TgeneDYNC1I1chr7:77166962chr7:95705369ENST000003249721317338_378520646.0RepeatNote=WD 2
TgeneDYNC1I1chr7:77166962chr7:95705369ENST000003249721317387_428520646.0RepeatNote=WD 3
TgeneDYNC1I1chr7:77166962chr7:95705369ENST000003249721317437_477520646.0RepeatNote=WD 4
TgeneDYNC1I1chr7:77166962chr7:95705369ENST000003249721317482_527520646.0RepeatNote=WD 5
TgeneDYNC1I1chr7:77166962chr7:95705369ENST000003593881216285_334483609.0RepeatNote=WD 1
TgeneDYNC1I1chr7:77166962chr7:95705369ENST000003593881216338_378483609.0RepeatNote=WD 2
TgeneDYNC1I1chr7:77166962chr7:95705369ENST000003593881216387_428483609.0RepeatNote=WD 3
TgeneDYNC1I1chr7:77166962chr7:95705369ENST000003593881216437_477483609.0RepeatNote=WD 4
TgeneDYNC1I1chr7:77166962chr7:95705369ENST000004474671317285_334503629.0RepeatNote=WD 1
TgeneDYNC1I1chr7:77166962chr7:95705369ENST000004474671317338_378503629.0RepeatNote=WD 2
TgeneDYNC1I1chr7:77166962chr7:95705369ENST000004474671317387_428503629.0RepeatNote=WD 3
TgeneDYNC1I1chr7:77166962chr7:95705369ENST000004474671317437_477503629.0RepeatNote=WD 4
TgeneDYNC1I1chr7:77166962chr7:95705369ENST000004474671317482_527503629.0RepeatNote=WD 5
TgeneDYNC1I1chr7:77166962chr7:95705369ENST000004570591317285_334503629.0RepeatNote=WD 1
TgeneDYNC1I1chr7:77166962chr7:95705369ENST000004570591317338_378503629.0RepeatNote=WD 2
TgeneDYNC1I1chr7:77166962chr7:95705369ENST000004570591317387_428503629.0RepeatNote=WD 3
TgeneDYNC1I1chr7:77166962chr7:95705369ENST000004570591317437_477503629.0RepeatNote=WD 4
TgeneDYNC1I1chr7:77166962chr7:95705369ENST000004570591317482_527503629.0RepeatNote=WD 5


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Fusion Gene Sequence for PTPN12-DYNC1I1


check button For in-frame fusion transcripts, we provide the fusion transcript sequences and fusion amino acid sequences. To have fusion amino acid sequence, we ran ORFfinder and chose the longest ORF among the all predicted ones.
>70191_70191_1_PTPN12-DYNC1I1_PTPN12_chr7_77166961_ENST00000248594_DYNC1I1_chr7_95705368_ENST00000324972_length(transcript)=1568nt_BP=371nt
AGCTGGGGGTTGGGGTTGGCGCTAGCGCAGCGGCTCGCCTGGTACTGTGGGAGAGCGGCGGCTGCTCCTGGAAGTTGTGGTGTCGGGAGC
CCAGCCGGTGCCGCCGCAGCCGCCGCCTAGGGCGGTGGGGAGGAGGAGGGAGCCGCGGGGCTTGGCGGGGTCGGGAGGGAGGGACGTGCT
GGGGGAACGAGCTGGGGAAGACGGAGCGGGCTCTGTGCCGGGCGGGCGGGCGGCGGGGGGGCCAGCGACCGCAGCCGGGGGGACGCGGGA
GGATGGAGCAAGTGGAGATCCTGAGGAAATTCATCCAGAGGGTCCAGGCCATGAAGAGTCCTGACCACAATGGGGAGGACAACTTCGCCC
GGGACTTCATGCACAACAAGCCGCTCTACTCCTTTGAAGACAATGCAGACTATGTGTACGATGTCATGTGGTCCCCCGTGCATCCTGCGC
TTTTTGCCTGCGTGGACGGGATGGGGCGCTTGGACCTCTGGAACCTCAACAATGACACCGAGGTTCCAACAGCAAGTGTGGCCATTGAGG
GGGCATCCGCCCTAAACCGTGTTCGTTGGGCCCAAGCTGGCAAAGAAGTTGCTGTTGGGGACTCGGAAGGCCGTATTTGGGTCTATGACG
TTGGAGAGCTTGCAGTTCCCCACAATGATGAATGGACCCGATTTGCCAGGACCCTTGTGGAAATTCGTGCTAACAGAGCTGATAGCGAGG
AGGAAGGCACTGTTGAGTTATCTGCCTAGTGGAAATGAGCCACCCCCACTGCAGCCCCCACCTTTGTGTCCTAGAGCTCAGCGTCTGCAG
TCAAGTCTCTTGTATTCGGTGTCCATTCAGTATCAGTATTGCTGTGATATTTTGGGTGCCATATTGTGCCAGCTTTGCTCCAAGTATTCT
AAATGTGTCCCATCATGCTTTCCACTGACCCAAAATTCACCACAGCATTTCTATCTTTATATTTCTGTCTCAAAAATGAAGAGAAGGGGG
TTATGGGTTAAGTTGCTGCCTTTTAACTACTTTGTAGCTGTATTTAATAGCTGGAAACCTCTGGTTAAATTTGTGCTTACATGCACTCCT
GGCATAGTCCTATTAAATCCATATGAAGCCAGATATGATTGGGTGCAGATGTGGTGTTCCTCATATTATGGTACAGGGCCAAAGACTTGA
GACGTGGTGTTTTACATGGTGACTCACATTATGAATGGATTTACTAGAAGAACATTGCTGCTCCTTATTTATTGTAGTGTGCTGCATGGA
ACGTATTTATTTGAAAGCATTAAAATAAATGATCCTAGAGCATGTGCATAATGAGAGGACTGTATTCTCTCTGCTGCTGTTGAGGTTATA
TTAAGTTCCACATAGCAATTACAGTATGCCAGTTCCACTGAAGACATGAAATCTTTAGAGGTTTCTTGCAGTGAACGAAATGAATTTTAA
TGCCTATTATTTCTGGGTACTTTAACAATATTTCAAATATCATTGACCACTAATACTTCTCACTGAAGCTAACACAGTCTGACAAAAGTC

>70191_70191_1_PTPN12-DYNC1I1_PTPN12_chr7_77166961_ENST00000248594_DYNC1I1_chr7_95705368_ENST00000324972_length(amino acids)=248AA_BP=123
LGVGVGASAAARLVLWESGGCSWKLWCREPSRCRRSRRLGRWGGGGSRGAWRGREGGTCWGNELGKTERALCRAGGRRGGQRPQPGGRGR
MEQVEILRKFIQRVQAMKSPDHNGEDNFARDFMHNKPLYSFEDNADYVYDVMWSPVHPALFACVDGMGRLDLWNLNNDTEVPTASVAIEG

--------------------------------------------------------------
>70191_70191_2_PTPN12-DYNC1I1_PTPN12_chr7_77166961_ENST00000248594_DYNC1I1_chr7_95705368_ENST00000359388_length(transcript)=1580nt_BP=371nt
AGCTGGGGGTTGGGGTTGGCGCTAGCGCAGCGGCTCGCCTGGTACTGTGGGAGAGCGGCGGCTGCTCCTGGAAGTTGTGGTGTCGGGAGC
CCAGCCGGTGCCGCCGCAGCCGCCGCCTAGGGCGGTGGGGAGGAGGAGGGAGCCGCGGGGCTTGGCGGGGTCGGGAGGGAGGGACGTGCT
GGGGGAACGAGCTGGGGAAGACGGAGCGGGCTCTGTGCCGGGCGGGCGGGCGGCGGGGGGGCCAGCGACCGCAGCCGGGGGGACGCGGGA
GGATGGAGCAAGTGGAGATCCTGAGGAAATTCATCCAGAGGGTCCAGGCCATGAAGAGTCCTGACCACAATGGGGAGGACAACTTCGCCC
GGGACTTCATGCACAACAAGCCGCTCTACTCCTTTGAAGACAATGCAGACTATGTGTACGATGTCATGTGGTCCCCCGTGCATCCTGCGC
TTTTTGCCTGCGTGGACGGGATGGGGCGCTTGGACCTCTGGAACCTCAACAATGACACCGAGGTTCCAACAGCAAGTGTGGCCATTGAGG
GGGCATCCGCCCTAAACCGTGTTCGTTGGGCCCAAGCTGGCAAAGAAGTTGCTGTTGGGGACTCGGAAGGCCGTATTTGGGTCTATGACG
TTGGAGAGCTTGCAGTTCCCCACAATGATGAATGGACCCGATTTGCCAGGACCCTTGTGGAAATTCGTGCTAACAGAGCTGATAGCGAGG
AGGAAGGCACTGTTGAGTTATCTGCCTAGTGGAAATGAGCCACCCCCACTGCAGCCCCCACCTTTGTGTCCTAGAGCTCAGCGTCTGCAG
TCAAGTCTCTTGTATTCGGTGTCCATTCAGTATCAGTATTGCTGTGATATTTTGGGTGCCATATTGTGCCAGCTTTGCTCCAAGTATTCT
AAATGTGTCCCATCATGCTTTCCACTGACCCAAAATTCACCACAGCATTTCTATCTTTATATTTCTGTCTCAAAAATGAAGAGAAGGGGG
TTATGGGTTAAGTTGCTGCCTTTTAACTACTTTGTAGCTGTATTTAATAGCTGGAAACCTCTGGTTAAATTTGTGCTTACATGCACTCCT
GGCATAGTCCTATTAAATCCATATGAAGCCAGATATGATTGGGTGCAGATGTGGTGTTCCTCATATTATGGTACAGGGCCAAAGACTTGA
GACGTGGTGTTTTACATGGTGACTCACATTATGAATGGATTTACTAGAAGAACATTGCTGCTCCTTATTTATTGTAGTGTGCTGCATGGA
ACGTATTTATTTGAAAGCATTAAAATAAATGATCCTAGAGCATGTGCATAATGAGAGGACTGTATTCTCTCTGCTGCTGTTGAGGTTATA
TTAAGTTCCACATAGCAATTACAGTATGCCAGTTCCACTGAAGACATGAAATCTTTAGAGGTTTCTTGCAGTGAACGAAATGAATTTTAA
TGCCTATTATTTCTGGGTACTTTAACAATATTTCAAATATCATTGACCACTAATACTTCTCACTGAAGCTAACACAGTCTGACAAAAGTC

>70191_70191_2_PTPN12-DYNC1I1_PTPN12_chr7_77166961_ENST00000248594_DYNC1I1_chr7_95705368_ENST00000359388_length(amino acids)=248AA_BP=123
LGVGVGASAAARLVLWESGGCSWKLWCREPSRCRRSRRLGRWGGGGSRGAWRGREGGTCWGNELGKTERALCRAGGRRGGQRPQPGGRGR
MEQVEILRKFIQRVQAMKSPDHNGEDNFARDFMHNKPLYSFEDNADYVYDVMWSPVHPALFACVDGMGRLDLWNLNNDTEVPTASVAIEG

--------------------------------------------------------------
>70191_70191_3_PTPN12-DYNC1I1_PTPN12_chr7_77166961_ENST00000248594_DYNC1I1_chr7_95705368_ENST00000437599_length(transcript)=1580nt_BP=371nt
AGCTGGGGGTTGGGGTTGGCGCTAGCGCAGCGGCTCGCCTGGTACTGTGGGAGAGCGGCGGCTGCTCCTGGAAGTTGTGGTGTCGGGAGC
CCAGCCGGTGCCGCCGCAGCCGCCGCCTAGGGCGGTGGGGAGGAGGAGGGAGCCGCGGGGCTTGGCGGGGTCGGGAGGGAGGGACGTGCT
GGGGGAACGAGCTGGGGAAGACGGAGCGGGCTCTGTGCCGGGCGGGCGGGCGGCGGGGGGGCCAGCGACCGCAGCCGGGGGGACGCGGGA
GGATGGAGCAAGTGGAGATCCTGAGGAAATTCATCCAGAGGGTCCAGGCCATGAAGAGTCCTGACCACAATGGGGAGGACAACTTCGCCC
GGGACTTCATGCACAACAAGCCGCTCTACTCCTTTGAAGACAATGCAGACTATGTGTACGATGTCATGTGGTCCCCCGTGCATCCTGCGC
TTTTTGCCTGCGTGGACGGGATGGGGCGCTTGGACCTCTGGAACCTCAACAATGACACCGAGGTTCCAACAGCAAGTGTGGCCATTGAGG
GGGCATCCGCCCTAAACCGTGTTCGTTGGGCCCAAGCTGGCAAAGAAGTTGCTGTTGGGGACTCGGAAGGCCGTATTTGGGTCTATGACG
TTGGAGAGCTTGCAGTTCCCCACAATGATGAATGGACCCGATTTGCCAGGACCCTTGTGGAAATTCGTGCTAACAGAGCTGATAGCGAGG
AGGAAGGCACTGTTGAGTTATCTGCCTAGTGGAAATGAGCCACCCCCACTGCAGCCCCCACCTTTGTGTCCTAGAGCTCAGCGTCTGCAG
TCAAGTCTCTTGTATTCGGTGTCCATTCAGTATCAGTATTGCTGTGATATTTTGGGTGCCATATTGTGCCAGCTTTGCTCCAAGTATTCT
AAATGTGTCCCATCATGCTTTCCACTGACCCAAAATTCACCACAGCATTTCTATCTTTATATTTCTGTCTCAAAAATGAAGAGAAGGGGG
TTATGGGTTAAGTTGCTGCCTTTTAACTACTTTGTAGCTGTATTTAATAGCTGGAAACCTCTGGTTAAATTTGTGCTTACATGCACTCCT
GGCATAGTCCTATTAAATCCATATGAAGCCAGATATGATTGGGTGCAGATGTGGTGTTCCTCATATTATGGTACAGGGCCAAAGACTTGA
GACGTGGTGTTTTACATGGTGACTCACATTATGAATGGATTTACTAGAAGAACATTGCTGCTCCTTATTTATTGTAGTGTGCTGCATGGA
ACGTATTTATTTGAAAGCATTAAAATAAATGATCCTAGAGCATGTGCATAATGAGAGGACTGTATTCTCTCTGCTGCTGTTGAGGTTATA
TTAAGTTCCACATAGCAATTACAGTATGCCAGTTCCACTGAAGACATGAAATCTTTAGAGGTTTCTTGCAGTGAACGAAATGAATTTTAA
TGCCTATTATTTCTGGGTACTTTAACAATATTTCAAATATCATTGACCACTAATACTTCTCACTGAAGCTAACACAGTCTGACAAAAGTC

>70191_70191_3_PTPN12-DYNC1I1_PTPN12_chr7_77166961_ENST00000248594_DYNC1I1_chr7_95705368_ENST00000437599_length(amino acids)=248AA_BP=123
LGVGVGASAAARLVLWESGGCSWKLWCREPSRCRRSRRLGRWGGGGSRGAWRGREGGTCWGNELGKTERALCRAGGRRGGQRPQPGGRGR
MEQVEILRKFIQRVQAMKSPDHNGEDNFARDFMHNKPLYSFEDNADYVYDVMWSPVHPALFACVDGMGRLDLWNLNNDTEVPTASVAIEG

--------------------------------------------------------------
>70191_70191_4_PTPN12-DYNC1I1_PTPN12_chr7_77166961_ENST00000248594_DYNC1I1_chr7_95705368_ENST00000447467_length(transcript)=1580nt_BP=371nt
AGCTGGGGGTTGGGGTTGGCGCTAGCGCAGCGGCTCGCCTGGTACTGTGGGAGAGCGGCGGCTGCTCCTGGAAGTTGTGGTGTCGGGAGC
CCAGCCGGTGCCGCCGCAGCCGCCGCCTAGGGCGGTGGGGAGGAGGAGGGAGCCGCGGGGCTTGGCGGGGTCGGGAGGGAGGGACGTGCT
GGGGGAACGAGCTGGGGAAGACGGAGCGGGCTCTGTGCCGGGCGGGCGGGCGGCGGGGGGGCCAGCGACCGCAGCCGGGGGGACGCGGGA
GGATGGAGCAAGTGGAGATCCTGAGGAAATTCATCCAGAGGGTCCAGGCCATGAAGAGTCCTGACCACAATGGGGAGGACAACTTCGCCC
GGGACTTCATGCACAACAAGCCGCTCTACTCCTTTGAAGACAATGCAGACTATGTGTACGATGTCATGTGGTCCCCCGTGCATCCTGCGC
TTTTTGCCTGCGTGGACGGGATGGGGCGCTTGGACCTCTGGAACCTCAACAATGACACCGAGGTTCCAACAGCAAGTGTGGCCATTGAGG
GGGCATCCGCCCTAAACCGTGTTCGTTGGGCCCAAGCTGGCAAAGAAGTTGCTGTTGGGGACTCGGAAGGCCGTATTTGGGTCTATGACG
TTGGAGAGCTTGCAGTTCCCCACAATGATGAATGGACCCGATTTGCCAGGACCCTTGTGGAAATTCGTGCTAACAGAGCTGATAGCGAGG
AGGAAGGCACTGTTGAGTTATCTGCCTAGTGGAAATGAGCCACCCCCACTGCAGCCCCCACCTTTGTGTCCTAGAGCTCAGCGTCTGCAG
TCAAGTCTCTTGTATTCGGTGTCCATTCAGTATCAGTATTGCTGTGATATTTTGGGTGCCATATTGTGCCAGCTTTGCTCCAAGTATTCT
AAATGTGTCCCATCATGCTTTCCACTGACCCAAAATTCACCACAGCATTTCTATCTTTATATTTCTGTCTCAAAAATGAAGAGAAGGGGG
TTATGGGTTAAGTTGCTGCCTTTTAACTACTTTGTAGCTGTATTTAATAGCTGGAAACCTCTGGTTAAATTTGTGCTTACATGCACTCCT
GGCATAGTCCTATTAAATCCATATGAAGCCAGATATGATTGGGTGCAGATGTGGTGTTCCTCATATTATGGTACAGGGCCAAAGACTTGA
GACGTGGTGTTTTACATGGTGACTCACATTATGAATGGATTTACTAGAAGAACATTGCTGCTCCTTATTTATTGTAGTGTGCTGCATGGA
ACGTATTTATTTGAAAGCATTAAAATAAATGATCCTAGAGCATGTGCATAATGAGAGGACTGTATTCTCTCTGCTGCTGTTGAGGTTATA
TTAAGTTCCACATAGCAATTACAGTATGCCAGTTCCACTGAAGACATGAAATCTTTAGAGGTTTCTTGCAGTGAACGAAATGAATTTTAA
TGCCTATTATTTCTGGGTACTTTAACAATATTTCAAATATCATTGACCACTAATACTTCTCACTGAAGCTAACACAGTCTGACAAAAGTC

>70191_70191_4_PTPN12-DYNC1I1_PTPN12_chr7_77166961_ENST00000248594_DYNC1I1_chr7_95705368_ENST00000447467_length(amino acids)=248AA_BP=123
LGVGVGASAAARLVLWESGGCSWKLWCREPSRCRRSRRLGRWGGGGSRGAWRGREGGTCWGNELGKTERALCRAGGRRGGQRPQPGGRGR
MEQVEILRKFIQRVQAMKSPDHNGEDNFARDFMHNKPLYSFEDNADYVYDVMWSPVHPALFACVDGMGRLDLWNLNNDTEVPTASVAIEG

--------------------------------------------------------------
>70191_70191_5_PTPN12-DYNC1I1_PTPN12_chr7_77166961_ENST00000248594_DYNC1I1_chr7_95705368_ENST00000537881_length(transcript)=982nt_BP=371nt
AGCTGGGGGTTGGGGTTGGCGCTAGCGCAGCGGCTCGCCTGGTACTGTGGGAGAGCGGCGGCTGCTCCTGGAAGTTGTGGTGTCGGGAGC
CCAGCCGGTGCCGCCGCAGCCGCCGCCTAGGGCGGTGGGGAGGAGGAGGGAGCCGCGGGGCTTGGCGGGGTCGGGAGGGAGGGACGTGCT
GGGGGAACGAGCTGGGGAAGACGGAGCGGGCTCTGTGCCGGGCGGGCGGGCGGCGGGGGGGCCAGCGACCGCAGCCGGGGGGACGCGGGA
GGATGGAGCAAGTGGAGATCCTGAGGAAATTCATCCAGAGGGTCCAGGCCATGAAGAGTCCTGACCACAATGGGGAGGACAACTTCGCCC
GGGACTTCATGCACAACAAGCCGCTCTACTCCTTTGAAGACAATGCAGACTATGTGTACGATGTCATGTGGTCCCCCGTGCATCCTGCGC
TTTTTGCCTGCGTGGACGGGATGGGGCGCTTGGACCTCTGGAACCTCAACAATGACACCGAGGTTCCAACAGCAAGTGTGGCCATTGAGG
GGGCATCCGCCCTAAACCGTGTTCGTTGGGCCCAAGCTGGCAAAGAAGTTGCTGTTGGGGACTCGGAAGGCCGTATTTGGGTCTATGACG
TTGGAGAGGGTCTTGCTATGTTGCCAGGCTGGTCTCAAAATTCCTGGACTCAAGCAATCCTCCTATGTTGGCCTCCCAAAGTGCTGGGAT
TACAGACATGAGCCACTGTGCCCAGCTATGCCTGCTTGTTATATCAGCTACTGAGAGATGAGTACCAAAATCTGGAAGTATAATTGTGGA
TATCTTTTAGTTCTTTCAGTTCTATCAGCTTTTGTTTTCTGTATCCAAAGCTTTGTTATTAGGTGCCTACATATTGAGGATTTCATGTGT

>70191_70191_5_PTPN12-DYNC1I1_PTPN12_chr7_77166961_ENST00000248594_DYNC1I1_chr7_95705368_ENST00000537881_length(amino acids)=242AA_BP=123
LGVGVGASAAARLVLWESGGCSWKLWCREPSRCRRSRRLGRWGGGGSRGAWRGREGGTCWGNELGKTERALCRAGGRRGGQRPQPGGRGR
MEQVEILRKFIQRVQAMKSPDHNGEDNFARDFMHNKPLYSFEDNADYVYDVMWSPVHPALFACVDGMGRLDLWNLNNDTEVPTASVAIEG

--------------------------------------------------------------
>70191_70191_6_PTPN12-DYNC1I1_PTPN12_chr7_77166962_ENST00000248594_DYNC1I1_chr7_95705368_ENST00000324972_length(transcript)=1568nt_BP=371nt
AGCTGGGGGTTGGGGTTGGCGCTAGCGCAGCGGCTCGCCTGGTACTGTGGGAGAGCGGCGGCTGCTCCTGGAAGTTGTGGTGTCGGGAGC
CCAGCCGGTGCCGCCGCAGCCGCCGCCTAGGGCGGTGGGGAGGAGGAGGGAGCCGCGGGGCTTGGCGGGGTCGGGAGGGAGGGACGTGCT
GGGGGAACGAGCTGGGGAAGACGGAGCGGGCTCTGTGCCGGGCGGGCGGGCGGCGGGGGGGCCAGCGACCGCAGCCGGGGGGACGCGGGA
GGATGGAGCAAGTGGAGATCCTGAGGAAATTCATCCAGAGGGTCCAGGCCATGAAGAGTCCTGACCACAATGGGGAGGACAACTTCGCCC
GGGACTTCATGCACAACAAGCCGCTCTACTCCTTTGAAGACAATGCAGACTATGTGTACGATGTCATGTGGTCCCCCGTGCATCCTGCGC
TTTTTGCCTGCGTGGACGGGATGGGGCGCTTGGACCTCTGGAACCTCAACAATGACACCGAGGTTCCAACAGCAAGTGTGGCCATTGAGG
GGGCATCCGCCCTAAACCGTGTTCGTTGGGCCCAAGCTGGCAAAGAAGTTGCTGTTGGGGACTCGGAAGGCCGTATTTGGGTCTATGACG
TTGGAGAGCTTGCAGTTCCCCACAATGATGAATGGACCCGATTTGCCAGGACCCTTGTGGAAATTCGTGCTAACAGAGCTGATAGCGAGG
AGGAAGGCACTGTTGAGTTATCTGCCTAGTGGAAATGAGCCACCCCCACTGCAGCCCCCACCTTTGTGTCCTAGAGCTCAGCGTCTGCAG
TCAAGTCTCTTGTATTCGGTGTCCATTCAGTATCAGTATTGCTGTGATATTTTGGGTGCCATATTGTGCCAGCTTTGCTCCAAGTATTCT
AAATGTGTCCCATCATGCTTTCCACTGACCCAAAATTCACCACAGCATTTCTATCTTTATATTTCTGTCTCAAAAATGAAGAGAAGGGGG
TTATGGGTTAAGTTGCTGCCTTTTAACTACTTTGTAGCTGTATTTAATAGCTGGAAACCTCTGGTTAAATTTGTGCTTACATGCACTCCT
GGCATAGTCCTATTAAATCCATATGAAGCCAGATATGATTGGGTGCAGATGTGGTGTTCCTCATATTATGGTACAGGGCCAAAGACTTGA
GACGTGGTGTTTTACATGGTGACTCACATTATGAATGGATTTACTAGAAGAACATTGCTGCTCCTTATTTATTGTAGTGTGCTGCATGGA
ACGTATTTATTTGAAAGCATTAAAATAAATGATCCTAGAGCATGTGCATAATGAGAGGACTGTATTCTCTCTGCTGCTGTTGAGGTTATA
TTAAGTTCCACATAGCAATTACAGTATGCCAGTTCCACTGAAGACATGAAATCTTTAGAGGTTTCTTGCAGTGAACGAAATGAATTTTAA
TGCCTATTATTTCTGGGTACTTTAACAATATTTCAAATATCATTGACCACTAATACTTCTCACTGAAGCTAACACAGTCTGACAAAAGTC

>70191_70191_6_PTPN12-DYNC1I1_PTPN12_chr7_77166962_ENST00000248594_DYNC1I1_chr7_95705368_ENST00000324972_length(amino acids)=248AA_BP=123
LGVGVGASAAARLVLWESGGCSWKLWCREPSRCRRSRRLGRWGGGGSRGAWRGREGGTCWGNELGKTERALCRAGGRRGGQRPQPGGRGR
MEQVEILRKFIQRVQAMKSPDHNGEDNFARDFMHNKPLYSFEDNADYVYDVMWSPVHPALFACVDGMGRLDLWNLNNDTEVPTASVAIEG

--------------------------------------------------------------
>70191_70191_7_PTPN12-DYNC1I1_PTPN12_chr7_77166962_ENST00000248594_DYNC1I1_chr7_95705368_ENST00000359388_length(transcript)=1580nt_BP=371nt
AGCTGGGGGTTGGGGTTGGCGCTAGCGCAGCGGCTCGCCTGGTACTGTGGGAGAGCGGCGGCTGCTCCTGGAAGTTGTGGTGTCGGGAGC
CCAGCCGGTGCCGCCGCAGCCGCCGCCTAGGGCGGTGGGGAGGAGGAGGGAGCCGCGGGGCTTGGCGGGGTCGGGAGGGAGGGACGTGCT
GGGGGAACGAGCTGGGGAAGACGGAGCGGGCTCTGTGCCGGGCGGGCGGGCGGCGGGGGGGCCAGCGACCGCAGCCGGGGGGACGCGGGA
GGATGGAGCAAGTGGAGATCCTGAGGAAATTCATCCAGAGGGTCCAGGCCATGAAGAGTCCTGACCACAATGGGGAGGACAACTTCGCCC
GGGACTTCATGCACAACAAGCCGCTCTACTCCTTTGAAGACAATGCAGACTATGTGTACGATGTCATGTGGTCCCCCGTGCATCCTGCGC
TTTTTGCCTGCGTGGACGGGATGGGGCGCTTGGACCTCTGGAACCTCAACAATGACACCGAGGTTCCAACAGCAAGTGTGGCCATTGAGG
GGGCATCCGCCCTAAACCGTGTTCGTTGGGCCCAAGCTGGCAAAGAAGTTGCTGTTGGGGACTCGGAAGGCCGTATTTGGGTCTATGACG
TTGGAGAGCTTGCAGTTCCCCACAATGATGAATGGACCCGATTTGCCAGGACCCTTGTGGAAATTCGTGCTAACAGAGCTGATAGCGAGG
AGGAAGGCACTGTTGAGTTATCTGCCTAGTGGAAATGAGCCACCCCCACTGCAGCCCCCACCTTTGTGTCCTAGAGCTCAGCGTCTGCAG
TCAAGTCTCTTGTATTCGGTGTCCATTCAGTATCAGTATTGCTGTGATATTTTGGGTGCCATATTGTGCCAGCTTTGCTCCAAGTATTCT
AAATGTGTCCCATCATGCTTTCCACTGACCCAAAATTCACCACAGCATTTCTATCTTTATATTTCTGTCTCAAAAATGAAGAGAAGGGGG
TTATGGGTTAAGTTGCTGCCTTTTAACTACTTTGTAGCTGTATTTAATAGCTGGAAACCTCTGGTTAAATTTGTGCTTACATGCACTCCT
GGCATAGTCCTATTAAATCCATATGAAGCCAGATATGATTGGGTGCAGATGTGGTGTTCCTCATATTATGGTACAGGGCCAAAGACTTGA
GACGTGGTGTTTTACATGGTGACTCACATTATGAATGGATTTACTAGAAGAACATTGCTGCTCCTTATTTATTGTAGTGTGCTGCATGGA
ACGTATTTATTTGAAAGCATTAAAATAAATGATCCTAGAGCATGTGCATAATGAGAGGACTGTATTCTCTCTGCTGCTGTTGAGGTTATA
TTAAGTTCCACATAGCAATTACAGTATGCCAGTTCCACTGAAGACATGAAATCTTTAGAGGTTTCTTGCAGTGAACGAAATGAATTTTAA
TGCCTATTATTTCTGGGTACTTTAACAATATTTCAAATATCATTGACCACTAATACTTCTCACTGAAGCTAACACAGTCTGACAAAAGTC

>70191_70191_7_PTPN12-DYNC1I1_PTPN12_chr7_77166962_ENST00000248594_DYNC1I1_chr7_95705368_ENST00000359388_length(amino acids)=248AA_BP=123
LGVGVGASAAARLVLWESGGCSWKLWCREPSRCRRSRRLGRWGGGGSRGAWRGREGGTCWGNELGKTERALCRAGGRRGGQRPQPGGRGR
MEQVEILRKFIQRVQAMKSPDHNGEDNFARDFMHNKPLYSFEDNADYVYDVMWSPVHPALFACVDGMGRLDLWNLNNDTEVPTASVAIEG

--------------------------------------------------------------
>70191_70191_8_PTPN12-DYNC1I1_PTPN12_chr7_77166962_ENST00000248594_DYNC1I1_chr7_95705368_ENST00000437599_length(transcript)=1580nt_BP=371nt
AGCTGGGGGTTGGGGTTGGCGCTAGCGCAGCGGCTCGCCTGGTACTGTGGGAGAGCGGCGGCTGCTCCTGGAAGTTGTGGTGTCGGGAGC
CCAGCCGGTGCCGCCGCAGCCGCCGCCTAGGGCGGTGGGGAGGAGGAGGGAGCCGCGGGGCTTGGCGGGGTCGGGAGGGAGGGACGTGCT
GGGGGAACGAGCTGGGGAAGACGGAGCGGGCTCTGTGCCGGGCGGGCGGGCGGCGGGGGGGCCAGCGACCGCAGCCGGGGGGACGCGGGA
GGATGGAGCAAGTGGAGATCCTGAGGAAATTCATCCAGAGGGTCCAGGCCATGAAGAGTCCTGACCACAATGGGGAGGACAACTTCGCCC
GGGACTTCATGCACAACAAGCCGCTCTACTCCTTTGAAGACAATGCAGACTATGTGTACGATGTCATGTGGTCCCCCGTGCATCCTGCGC
TTTTTGCCTGCGTGGACGGGATGGGGCGCTTGGACCTCTGGAACCTCAACAATGACACCGAGGTTCCAACAGCAAGTGTGGCCATTGAGG
GGGCATCCGCCCTAAACCGTGTTCGTTGGGCCCAAGCTGGCAAAGAAGTTGCTGTTGGGGACTCGGAAGGCCGTATTTGGGTCTATGACG
TTGGAGAGCTTGCAGTTCCCCACAATGATGAATGGACCCGATTTGCCAGGACCCTTGTGGAAATTCGTGCTAACAGAGCTGATAGCGAGG
AGGAAGGCACTGTTGAGTTATCTGCCTAGTGGAAATGAGCCACCCCCACTGCAGCCCCCACCTTTGTGTCCTAGAGCTCAGCGTCTGCAG
TCAAGTCTCTTGTATTCGGTGTCCATTCAGTATCAGTATTGCTGTGATATTTTGGGTGCCATATTGTGCCAGCTTTGCTCCAAGTATTCT
AAATGTGTCCCATCATGCTTTCCACTGACCCAAAATTCACCACAGCATTTCTATCTTTATATTTCTGTCTCAAAAATGAAGAGAAGGGGG
TTATGGGTTAAGTTGCTGCCTTTTAACTACTTTGTAGCTGTATTTAATAGCTGGAAACCTCTGGTTAAATTTGTGCTTACATGCACTCCT
GGCATAGTCCTATTAAATCCATATGAAGCCAGATATGATTGGGTGCAGATGTGGTGTTCCTCATATTATGGTACAGGGCCAAAGACTTGA
GACGTGGTGTTTTACATGGTGACTCACATTATGAATGGATTTACTAGAAGAACATTGCTGCTCCTTATTTATTGTAGTGTGCTGCATGGA
ACGTATTTATTTGAAAGCATTAAAATAAATGATCCTAGAGCATGTGCATAATGAGAGGACTGTATTCTCTCTGCTGCTGTTGAGGTTATA
TTAAGTTCCACATAGCAATTACAGTATGCCAGTTCCACTGAAGACATGAAATCTTTAGAGGTTTCTTGCAGTGAACGAAATGAATTTTAA
TGCCTATTATTTCTGGGTACTTTAACAATATTTCAAATATCATTGACCACTAATACTTCTCACTGAAGCTAACACAGTCTGACAAAAGTC

>70191_70191_8_PTPN12-DYNC1I1_PTPN12_chr7_77166962_ENST00000248594_DYNC1I1_chr7_95705368_ENST00000437599_length(amino acids)=248AA_BP=123
LGVGVGASAAARLVLWESGGCSWKLWCREPSRCRRSRRLGRWGGGGSRGAWRGREGGTCWGNELGKTERALCRAGGRRGGQRPQPGGRGR
MEQVEILRKFIQRVQAMKSPDHNGEDNFARDFMHNKPLYSFEDNADYVYDVMWSPVHPALFACVDGMGRLDLWNLNNDTEVPTASVAIEG

--------------------------------------------------------------
>70191_70191_9_PTPN12-DYNC1I1_PTPN12_chr7_77166962_ENST00000248594_DYNC1I1_chr7_95705368_ENST00000447467_length(transcript)=1580nt_BP=371nt
AGCTGGGGGTTGGGGTTGGCGCTAGCGCAGCGGCTCGCCTGGTACTGTGGGAGAGCGGCGGCTGCTCCTGGAAGTTGTGGTGTCGGGAGC
CCAGCCGGTGCCGCCGCAGCCGCCGCCTAGGGCGGTGGGGAGGAGGAGGGAGCCGCGGGGCTTGGCGGGGTCGGGAGGGAGGGACGTGCT
GGGGGAACGAGCTGGGGAAGACGGAGCGGGCTCTGTGCCGGGCGGGCGGGCGGCGGGGGGGCCAGCGACCGCAGCCGGGGGGACGCGGGA
GGATGGAGCAAGTGGAGATCCTGAGGAAATTCATCCAGAGGGTCCAGGCCATGAAGAGTCCTGACCACAATGGGGAGGACAACTTCGCCC
GGGACTTCATGCACAACAAGCCGCTCTACTCCTTTGAAGACAATGCAGACTATGTGTACGATGTCATGTGGTCCCCCGTGCATCCTGCGC
TTTTTGCCTGCGTGGACGGGATGGGGCGCTTGGACCTCTGGAACCTCAACAATGACACCGAGGTTCCAACAGCAAGTGTGGCCATTGAGG
GGGCATCCGCCCTAAACCGTGTTCGTTGGGCCCAAGCTGGCAAAGAAGTTGCTGTTGGGGACTCGGAAGGCCGTATTTGGGTCTATGACG
TTGGAGAGCTTGCAGTTCCCCACAATGATGAATGGACCCGATTTGCCAGGACCCTTGTGGAAATTCGTGCTAACAGAGCTGATAGCGAGG
AGGAAGGCACTGTTGAGTTATCTGCCTAGTGGAAATGAGCCACCCCCACTGCAGCCCCCACCTTTGTGTCCTAGAGCTCAGCGTCTGCAG
TCAAGTCTCTTGTATTCGGTGTCCATTCAGTATCAGTATTGCTGTGATATTTTGGGTGCCATATTGTGCCAGCTTTGCTCCAAGTATTCT
AAATGTGTCCCATCATGCTTTCCACTGACCCAAAATTCACCACAGCATTTCTATCTTTATATTTCTGTCTCAAAAATGAAGAGAAGGGGG
TTATGGGTTAAGTTGCTGCCTTTTAACTACTTTGTAGCTGTATTTAATAGCTGGAAACCTCTGGTTAAATTTGTGCTTACATGCACTCCT
GGCATAGTCCTATTAAATCCATATGAAGCCAGATATGATTGGGTGCAGATGTGGTGTTCCTCATATTATGGTACAGGGCCAAAGACTTGA
GACGTGGTGTTTTACATGGTGACTCACATTATGAATGGATTTACTAGAAGAACATTGCTGCTCCTTATTTATTGTAGTGTGCTGCATGGA
ACGTATTTATTTGAAAGCATTAAAATAAATGATCCTAGAGCATGTGCATAATGAGAGGACTGTATTCTCTCTGCTGCTGTTGAGGTTATA
TTAAGTTCCACATAGCAATTACAGTATGCCAGTTCCACTGAAGACATGAAATCTTTAGAGGTTTCTTGCAGTGAACGAAATGAATTTTAA
TGCCTATTATTTCTGGGTACTTTAACAATATTTCAAATATCATTGACCACTAATACTTCTCACTGAAGCTAACACAGTCTGACAAAAGTC

>70191_70191_9_PTPN12-DYNC1I1_PTPN12_chr7_77166962_ENST00000248594_DYNC1I1_chr7_95705368_ENST00000447467_length(amino acids)=248AA_BP=123
LGVGVGASAAARLVLWESGGCSWKLWCREPSRCRRSRRLGRWGGGGSRGAWRGREGGTCWGNELGKTERALCRAGGRRGGQRPQPGGRGR
MEQVEILRKFIQRVQAMKSPDHNGEDNFARDFMHNKPLYSFEDNADYVYDVMWSPVHPALFACVDGMGRLDLWNLNNDTEVPTASVAIEG

--------------------------------------------------------------
>70191_70191_10_PTPN12-DYNC1I1_PTPN12_chr7_77166962_ENST00000248594_DYNC1I1_chr7_95705368_ENST00000537881_length(transcript)=982nt_BP=371nt
AGCTGGGGGTTGGGGTTGGCGCTAGCGCAGCGGCTCGCCTGGTACTGTGGGAGAGCGGCGGCTGCTCCTGGAAGTTGTGGTGTCGGGAGC
CCAGCCGGTGCCGCCGCAGCCGCCGCCTAGGGCGGTGGGGAGGAGGAGGGAGCCGCGGGGCTTGGCGGGGTCGGGAGGGAGGGACGTGCT
GGGGGAACGAGCTGGGGAAGACGGAGCGGGCTCTGTGCCGGGCGGGCGGGCGGCGGGGGGGCCAGCGACCGCAGCCGGGGGGACGCGGGA
GGATGGAGCAAGTGGAGATCCTGAGGAAATTCATCCAGAGGGTCCAGGCCATGAAGAGTCCTGACCACAATGGGGAGGACAACTTCGCCC
GGGACTTCATGCACAACAAGCCGCTCTACTCCTTTGAAGACAATGCAGACTATGTGTACGATGTCATGTGGTCCCCCGTGCATCCTGCGC
TTTTTGCCTGCGTGGACGGGATGGGGCGCTTGGACCTCTGGAACCTCAACAATGACACCGAGGTTCCAACAGCAAGTGTGGCCATTGAGG
GGGCATCCGCCCTAAACCGTGTTCGTTGGGCCCAAGCTGGCAAAGAAGTTGCTGTTGGGGACTCGGAAGGCCGTATTTGGGTCTATGACG
TTGGAGAGGGTCTTGCTATGTTGCCAGGCTGGTCTCAAAATTCCTGGACTCAAGCAATCCTCCTATGTTGGCCTCCCAAAGTGCTGGGAT
TACAGACATGAGCCACTGTGCCCAGCTATGCCTGCTTGTTATATCAGCTACTGAGAGATGAGTACCAAAATCTGGAAGTATAATTGTGGA
TATCTTTTAGTTCTTTCAGTTCTATCAGCTTTTGTTTTCTGTATCCAAAGCTTTGTTATTAGGTGCCTACATATTGAGGATTTCATGTGT

>70191_70191_10_PTPN12-DYNC1I1_PTPN12_chr7_77166962_ENST00000248594_DYNC1I1_chr7_95705368_ENST00000537881_length(amino acids)=242AA_BP=123
LGVGVGASAAARLVLWESGGCSWKLWCREPSRCRRSRRLGRWGGGGSRGAWRGREGGTCWGNELGKTERALCRAGGRRGGQRPQPGGRGR
MEQVEILRKFIQRVQAMKSPDHNGEDNFARDFMHNKPLYSFEDNADYVYDVMWSPVHPALFACVDGMGRLDLWNLNNDTEVPTASVAIEG

--------------------------------------------------------------
>70191_70191_11_PTPN12-DYNC1I1_PTPN12_chr7_77166962_ENST00000248594_DYNC1I1_chr7_95705369_ENST00000324972_length(transcript)=1568nt_BP=371nt
AGCTGGGGGTTGGGGTTGGCGCTAGCGCAGCGGCTCGCCTGGTACTGTGGGAGAGCGGCGGCTGCTCCTGGAAGTTGTGGTGTCGGGAGC
CCAGCCGGTGCCGCCGCAGCCGCCGCCTAGGGCGGTGGGGAGGAGGAGGGAGCCGCGGGGCTTGGCGGGGTCGGGAGGGAGGGACGTGCT
GGGGGAACGAGCTGGGGAAGACGGAGCGGGCTCTGTGCCGGGCGGGCGGGCGGCGGGGGGGCCAGCGACCGCAGCCGGGGGGACGCGGGA
GGATGGAGCAAGTGGAGATCCTGAGGAAATTCATCCAGAGGGTCCAGGCCATGAAGAGTCCTGACCACAATGGGGAGGACAACTTCGCCC
GGGACTTCATGCACAACAAGCCGCTCTACTCCTTTGAAGACAATGCAGACTATGTGTACGATGTCATGTGGTCCCCCGTGCATCCTGCGC
TTTTTGCCTGCGTGGACGGGATGGGGCGCTTGGACCTCTGGAACCTCAACAATGACACCGAGGTTCCAACAGCAAGTGTGGCCATTGAGG
GGGCATCCGCCCTAAACCGTGTTCGTTGGGCCCAAGCTGGCAAAGAAGTTGCTGTTGGGGACTCGGAAGGCCGTATTTGGGTCTATGACG
TTGGAGAGCTTGCAGTTCCCCACAATGATGAATGGACCCGATTTGCCAGGACCCTTGTGGAAATTCGTGCTAACAGAGCTGATAGCGAGG
AGGAAGGCACTGTTGAGTTATCTGCCTAGTGGAAATGAGCCACCCCCACTGCAGCCCCCACCTTTGTGTCCTAGAGCTCAGCGTCTGCAG
TCAAGTCTCTTGTATTCGGTGTCCATTCAGTATCAGTATTGCTGTGATATTTTGGGTGCCATATTGTGCCAGCTTTGCTCCAAGTATTCT
AAATGTGTCCCATCATGCTTTCCACTGACCCAAAATTCACCACAGCATTTCTATCTTTATATTTCTGTCTCAAAAATGAAGAGAAGGGGG
TTATGGGTTAAGTTGCTGCCTTTTAACTACTTTGTAGCTGTATTTAATAGCTGGAAACCTCTGGTTAAATTTGTGCTTACATGCACTCCT
GGCATAGTCCTATTAAATCCATATGAAGCCAGATATGATTGGGTGCAGATGTGGTGTTCCTCATATTATGGTACAGGGCCAAAGACTTGA
GACGTGGTGTTTTACATGGTGACTCACATTATGAATGGATTTACTAGAAGAACATTGCTGCTCCTTATTTATTGTAGTGTGCTGCATGGA
ACGTATTTATTTGAAAGCATTAAAATAAATGATCCTAGAGCATGTGCATAATGAGAGGACTGTATTCTCTCTGCTGCTGTTGAGGTTATA
TTAAGTTCCACATAGCAATTACAGTATGCCAGTTCCACTGAAGACATGAAATCTTTAGAGGTTTCTTGCAGTGAACGAAATGAATTTTAA
TGCCTATTATTTCTGGGTACTTTAACAATATTTCAAATATCATTGACCACTAATACTTCTCACTGAAGCTAACACAGTCTGACAAAAGTC

>70191_70191_11_PTPN12-DYNC1I1_PTPN12_chr7_77166962_ENST00000248594_DYNC1I1_chr7_95705369_ENST00000324972_length(amino acids)=248AA_BP=123
LGVGVGASAAARLVLWESGGCSWKLWCREPSRCRRSRRLGRWGGGGSRGAWRGREGGTCWGNELGKTERALCRAGGRRGGQRPQPGGRGR
MEQVEILRKFIQRVQAMKSPDHNGEDNFARDFMHNKPLYSFEDNADYVYDVMWSPVHPALFACVDGMGRLDLWNLNNDTEVPTASVAIEG

--------------------------------------------------------------
>70191_70191_12_PTPN12-DYNC1I1_PTPN12_chr7_77166962_ENST00000248594_DYNC1I1_chr7_95705369_ENST00000359388_length(transcript)=1580nt_BP=371nt
AGCTGGGGGTTGGGGTTGGCGCTAGCGCAGCGGCTCGCCTGGTACTGTGGGAGAGCGGCGGCTGCTCCTGGAAGTTGTGGTGTCGGGAGC
CCAGCCGGTGCCGCCGCAGCCGCCGCCTAGGGCGGTGGGGAGGAGGAGGGAGCCGCGGGGCTTGGCGGGGTCGGGAGGGAGGGACGTGCT
GGGGGAACGAGCTGGGGAAGACGGAGCGGGCTCTGTGCCGGGCGGGCGGGCGGCGGGGGGGCCAGCGACCGCAGCCGGGGGGACGCGGGA
GGATGGAGCAAGTGGAGATCCTGAGGAAATTCATCCAGAGGGTCCAGGCCATGAAGAGTCCTGACCACAATGGGGAGGACAACTTCGCCC
GGGACTTCATGCACAACAAGCCGCTCTACTCCTTTGAAGACAATGCAGACTATGTGTACGATGTCATGTGGTCCCCCGTGCATCCTGCGC
TTTTTGCCTGCGTGGACGGGATGGGGCGCTTGGACCTCTGGAACCTCAACAATGACACCGAGGTTCCAACAGCAAGTGTGGCCATTGAGG
GGGCATCCGCCCTAAACCGTGTTCGTTGGGCCCAAGCTGGCAAAGAAGTTGCTGTTGGGGACTCGGAAGGCCGTATTTGGGTCTATGACG
TTGGAGAGCTTGCAGTTCCCCACAATGATGAATGGACCCGATTTGCCAGGACCCTTGTGGAAATTCGTGCTAACAGAGCTGATAGCGAGG
AGGAAGGCACTGTTGAGTTATCTGCCTAGTGGAAATGAGCCACCCCCACTGCAGCCCCCACCTTTGTGTCCTAGAGCTCAGCGTCTGCAG
TCAAGTCTCTTGTATTCGGTGTCCATTCAGTATCAGTATTGCTGTGATATTTTGGGTGCCATATTGTGCCAGCTTTGCTCCAAGTATTCT
AAATGTGTCCCATCATGCTTTCCACTGACCCAAAATTCACCACAGCATTTCTATCTTTATATTTCTGTCTCAAAAATGAAGAGAAGGGGG
TTATGGGTTAAGTTGCTGCCTTTTAACTACTTTGTAGCTGTATTTAATAGCTGGAAACCTCTGGTTAAATTTGTGCTTACATGCACTCCT
GGCATAGTCCTATTAAATCCATATGAAGCCAGATATGATTGGGTGCAGATGTGGTGTTCCTCATATTATGGTACAGGGCCAAAGACTTGA
GACGTGGTGTTTTACATGGTGACTCACATTATGAATGGATTTACTAGAAGAACATTGCTGCTCCTTATTTATTGTAGTGTGCTGCATGGA
ACGTATTTATTTGAAAGCATTAAAATAAATGATCCTAGAGCATGTGCATAATGAGAGGACTGTATTCTCTCTGCTGCTGTTGAGGTTATA
TTAAGTTCCACATAGCAATTACAGTATGCCAGTTCCACTGAAGACATGAAATCTTTAGAGGTTTCTTGCAGTGAACGAAATGAATTTTAA
TGCCTATTATTTCTGGGTACTTTAACAATATTTCAAATATCATTGACCACTAATACTTCTCACTGAAGCTAACACAGTCTGACAAAAGTC

>70191_70191_12_PTPN12-DYNC1I1_PTPN12_chr7_77166962_ENST00000248594_DYNC1I1_chr7_95705369_ENST00000359388_length(amino acids)=248AA_BP=123
LGVGVGASAAARLVLWESGGCSWKLWCREPSRCRRSRRLGRWGGGGSRGAWRGREGGTCWGNELGKTERALCRAGGRRGGQRPQPGGRGR
MEQVEILRKFIQRVQAMKSPDHNGEDNFARDFMHNKPLYSFEDNADYVYDVMWSPVHPALFACVDGMGRLDLWNLNNDTEVPTASVAIEG

--------------------------------------------------------------
>70191_70191_13_PTPN12-DYNC1I1_PTPN12_chr7_77166962_ENST00000248594_DYNC1I1_chr7_95705369_ENST00000437599_length(transcript)=1580nt_BP=371nt
AGCTGGGGGTTGGGGTTGGCGCTAGCGCAGCGGCTCGCCTGGTACTGTGGGAGAGCGGCGGCTGCTCCTGGAAGTTGTGGTGTCGGGAGC
CCAGCCGGTGCCGCCGCAGCCGCCGCCTAGGGCGGTGGGGAGGAGGAGGGAGCCGCGGGGCTTGGCGGGGTCGGGAGGGAGGGACGTGCT
GGGGGAACGAGCTGGGGAAGACGGAGCGGGCTCTGTGCCGGGCGGGCGGGCGGCGGGGGGGCCAGCGACCGCAGCCGGGGGGACGCGGGA
GGATGGAGCAAGTGGAGATCCTGAGGAAATTCATCCAGAGGGTCCAGGCCATGAAGAGTCCTGACCACAATGGGGAGGACAACTTCGCCC
GGGACTTCATGCACAACAAGCCGCTCTACTCCTTTGAAGACAATGCAGACTATGTGTACGATGTCATGTGGTCCCCCGTGCATCCTGCGC
TTTTTGCCTGCGTGGACGGGATGGGGCGCTTGGACCTCTGGAACCTCAACAATGACACCGAGGTTCCAACAGCAAGTGTGGCCATTGAGG
GGGCATCCGCCCTAAACCGTGTTCGTTGGGCCCAAGCTGGCAAAGAAGTTGCTGTTGGGGACTCGGAAGGCCGTATTTGGGTCTATGACG
TTGGAGAGCTTGCAGTTCCCCACAATGATGAATGGACCCGATTTGCCAGGACCCTTGTGGAAATTCGTGCTAACAGAGCTGATAGCGAGG
AGGAAGGCACTGTTGAGTTATCTGCCTAGTGGAAATGAGCCACCCCCACTGCAGCCCCCACCTTTGTGTCCTAGAGCTCAGCGTCTGCAG
TCAAGTCTCTTGTATTCGGTGTCCATTCAGTATCAGTATTGCTGTGATATTTTGGGTGCCATATTGTGCCAGCTTTGCTCCAAGTATTCT
AAATGTGTCCCATCATGCTTTCCACTGACCCAAAATTCACCACAGCATTTCTATCTTTATATTTCTGTCTCAAAAATGAAGAGAAGGGGG
TTATGGGTTAAGTTGCTGCCTTTTAACTACTTTGTAGCTGTATTTAATAGCTGGAAACCTCTGGTTAAATTTGTGCTTACATGCACTCCT
GGCATAGTCCTATTAAATCCATATGAAGCCAGATATGATTGGGTGCAGATGTGGTGTTCCTCATATTATGGTACAGGGCCAAAGACTTGA
GACGTGGTGTTTTACATGGTGACTCACATTATGAATGGATTTACTAGAAGAACATTGCTGCTCCTTATTTATTGTAGTGTGCTGCATGGA
ACGTATTTATTTGAAAGCATTAAAATAAATGATCCTAGAGCATGTGCATAATGAGAGGACTGTATTCTCTCTGCTGCTGTTGAGGTTATA
TTAAGTTCCACATAGCAATTACAGTATGCCAGTTCCACTGAAGACATGAAATCTTTAGAGGTTTCTTGCAGTGAACGAAATGAATTTTAA
TGCCTATTATTTCTGGGTACTTTAACAATATTTCAAATATCATTGACCACTAATACTTCTCACTGAAGCTAACACAGTCTGACAAAAGTC

>70191_70191_13_PTPN12-DYNC1I1_PTPN12_chr7_77166962_ENST00000248594_DYNC1I1_chr7_95705369_ENST00000437599_length(amino acids)=248AA_BP=123
LGVGVGASAAARLVLWESGGCSWKLWCREPSRCRRSRRLGRWGGGGSRGAWRGREGGTCWGNELGKTERALCRAGGRRGGQRPQPGGRGR
MEQVEILRKFIQRVQAMKSPDHNGEDNFARDFMHNKPLYSFEDNADYVYDVMWSPVHPALFACVDGMGRLDLWNLNNDTEVPTASVAIEG

--------------------------------------------------------------
>70191_70191_14_PTPN12-DYNC1I1_PTPN12_chr7_77166962_ENST00000248594_DYNC1I1_chr7_95705369_ENST00000447467_length(transcript)=1580nt_BP=371nt
AGCTGGGGGTTGGGGTTGGCGCTAGCGCAGCGGCTCGCCTGGTACTGTGGGAGAGCGGCGGCTGCTCCTGGAAGTTGTGGTGTCGGGAGC
CCAGCCGGTGCCGCCGCAGCCGCCGCCTAGGGCGGTGGGGAGGAGGAGGGAGCCGCGGGGCTTGGCGGGGTCGGGAGGGAGGGACGTGCT
GGGGGAACGAGCTGGGGAAGACGGAGCGGGCTCTGTGCCGGGCGGGCGGGCGGCGGGGGGGCCAGCGACCGCAGCCGGGGGGACGCGGGA
GGATGGAGCAAGTGGAGATCCTGAGGAAATTCATCCAGAGGGTCCAGGCCATGAAGAGTCCTGACCACAATGGGGAGGACAACTTCGCCC
GGGACTTCATGCACAACAAGCCGCTCTACTCCTTTGAAGACAATGCAGACTATGTGTACGATGTCATGTGGTCCCCCGTGCATCCTGCGC
TTTTTGCCTGCGTGGACGGGATGGGGCGCTTGGACCTCTGGAACCTCAACAATGACACCGAGGTTCCAACAGCAAGTGTGGCCATTGAGG
GGGCATCCGCCCTAAACCGTGTTCGTTGGGCCCAAGCTGGCAAAGAAGTTGCTGTTGGGGACTCGGAAGGCCGTATTTGGGTCTATGACG
TTGGAGAGCTTGCAGTTCCCCACAATGATGAATGGACCCGATTTGCCAGGACCCTTGTGGAAATTCGTGCTAACAGAGCTGATAGCGAGG
AGGAAGGCACTGTTGAGTTATCTGCCTAGTGGAAATGAGCCACCCCCACTGCAGCCCCCACCTTTGTGTCCTAGAGCTCAGCGTCTGCAG
TCAAGTCTCTTGTATTCGGTGTCCATTCAGTATCAGTATTGCTGTGATATTTTGGGTGCCATATTGTGCCAGCTTTGCTCCAAGTATTCT
AAATGTGTCCCATCATGCTTTCCACTGACCCAAAATTCACCACAGCATTTCTATCTTTATATTTCTGTCTCAAAAATGAAGAGAAGGGGG
TTATGGGTTAAGTTGCTGCCTTTTAACTACTTTGTAGCTGTATTTAATAGCTGGAAACCTCTGGTTAAATTTGTGCTTACATGCACTCCT
GGCATAGTCCTATTAAATCCATATGAAGCCAGATATGATTGGGTGCAGATGTGGTGTTCCTCATATTATGGTACAGGGCCAAAGACTTGA
GACGTGGTGTTTTACATGGTGACTCACATTATGAATGGATTTACTAGAAGAACATTGCTGCTCCTTATTTATTGTAGTGTGCTGCATGGA
ACGTATTTATTTGAAAGCATTAAAATAAATGATCCTAGAGCATGTGCATAATGAGAGGACTGTATTCTCTCTGCTGCTGTTGAGGTTATA
TTAAGTTCCACATAGCAATTACAGTATGCCAGTTCCACTGAAGACATGAAATCTTTAGAGGTTTCTTGCAGTGAACGAAATGAATTTTAA
TGCCTATTATTTCTGGGTACTTTAACAATATTTCAAATATCATTGACCACTAATACTTCTCACTGAAGCTAACACAGTCTGACAAAAGTC

>70191_70191_14_PTPN12-DYNC1I1_PTPN12_chr7_77166962_ENST00000248594_DYNC1I1_chr7_95705369_ENST00000447467_length(amino acids)=248AA_BP=123
LGVGVGASAAARLVLWESGGCSWKLWCREPSRCRRSRRLGRWGGGGSRGAWRGREGGTCWGNELGKTERALCRAGGRRGGQRPQPGGRGR
MEQVEILRKFIQRVQAMKSPDHNGEDNFARDFMHNKPLYSFEDNADYVYDVMWSPVHPALFACVDGMGRLDLWNLNNDTEVPTASVAIEG

--------------------------------------------------------------
>70191_70191_15_PTPN12-DYNC1I1_PTPN12_chr7_77166962_ENST00000248594_DYNC1I1_chr7_95705369_ENST00000537881_length(transcript)=982nt_BP=371nt
AGCTGGGGGTTGGGGTTGGCGCTAGCGCAGCGGCTCGCCTGGTACTGTGGGAGAGCGGCGGCTGCTCCTGGAAGTTGTGGTGTCGGGAGC
CCAGCCGGTGCCGCCGCAGCCGCCGCCTAGGGCGGTGGGGAGGAGGAGGGAGCCGCGGGGCTTGGCGGGGTCGGGAGGGAGGGACGTGCT
GGGGGAACGAGCTGGGGAAGACGGAGCGGGCTCTGTGCCGGGCGGGCGGGCGGCGGGGGGGCCAGCGACCGCAGCCGGGGGGACGCGGGA
GGATGGAGCAAGTGGAGATCCTGAGGAAATTCATCCAGAGGGTCCAGGCCATGAAGAGTCCTGACCACAATGGGGAGGACAACTTCGCCC
GGGACTTCATGCACAACAAGCCGCTCTACTCCTTTGAAGACAATGCAGACTATGTGTACGATGTCATGTGGTCCCCCGTGCATCCTGCGC
TTTTTGCCTGCGTGGACGGGATGGGGCGCTTGGACCTCTGGAACCTCAACAATGACACCGAGGTTCCAACAGCAAGTGTGGCCATTGAGG
GGGCATCCGCCCTAAACCGTGTTCGTTGGGCCCAAGCTGGCAAAGAAGTTGCTGTTGGGGACTCGGAAGGCCGTATTTGGGTCTATGACG
TTGGAGAGGGTCTTGCTATGTTGCCAGGCTGGTCTCAAAATTCCTGGACTCAAGCAATCCTCCTATGTTGGCCTCCCAAAGTGCTGGGAT
TACAGACATGAGCCACTGTGCCCAGCTATGCCTGCTTGTTATATCAGCTACTGAGAGATGAGTACCAAAATCTGGAAGTATAATTGTGGA
TATCTTTTAGTTCTTTCAGTTCTATCAGCTTTTGTTTTCTGTATCCAAAGCTTTGTTATTAGGTGCCTACATATTGAGGATTTCATGTGT

>70191_70191_15_PTPN12-DYNC1I1_PTPN12_chr7_77166962_ENST00000248594_DYNC1I1_chr7_95705369_ENST00000537881_length(amino acids)=242AA_BP=123
LGVGVGASAAARLVLWESGGCSWKLWCREPSRCRRSRRLGRWGGGGSRGAWRGREGGTCWGNELGKTERALCRAGGRRGGQRPQPGGRGR
MEQVEILRKFIQRVQAMKSPDHNGEDNFARDFMHNKPLYSFEDNADYVYDVMWSPVHPALFACVDGMGRLDLWNLNNDTEVPTASVAIEG

--------------------------------------------------------------

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Fusion Gene PPI Analysis for PTPN12-DYNC1I1


check button Go to ChiPPI (Chimeric Protein-Protein interactions) to see the chimeric PPI interaction in

ChiPPI page.


check button Protein-protein interactors with each fusion partner protein in wild-type (BIOGRID-3.4.160)
HgeneHgene's interactorsTgeneTgene's interactors


check button - Retained PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenStill interaction with


check button - Lost PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with
HgenePTPN12chr7:77166961chr7:95705368ENST00000248594+118345_43833.0781.0TGFB1I1
HgenePTPN12chr7:77166961chr7:95705368ENST00000435495+117345_4380651.0TGFB1I1
HgenePTPN12chr7:77166962chr7:95705368ENST00000248594+118345_43833.0781.0TGFB1I1
HgenePTPN12chr7:77166962chr7:95705368ENST00000435495+117345_4380651.0TGFB1I1
HgenePTPN12chr7:77166962chr7:95705369ENST00000248594+118345_43833.0781.0TGFB1I1
HgenePTPN12chr7:77166962chr7:95705369ENST00000435495+117345_4380651.0TGFB1I1
TgeneDYNC1I1chr7:77166961chr7:95705368ENST0000032497213172_123520.0646.0DCTN1
TgeneDYNC1I1chr7:77166961chr7:95705368ENST0000035938812162_123483.0609.0DCTN1
TgeneDYNC1I1chr7:77166961chr7:95705368ENST0000044746713172_123503.0629.0DCTN1
TgeneDYNC1I1chr7:77166961chr7:95705368ENST0000045705913172_123503.0629.0DCTN1
TgeneDYNC1I1chr7:77166962chr7:95705368ENST0000032497213172_123520.0646.0DCTN1
TgeneDYNC1I1chr7:77166962chr7:95705368ENST0000035938812162_123483.0609.0DCTN1
TgeneDYNC1I1chr7:77166962chr7:95705368ENST0000044746713172_123503.0629.0DCTN1
TgeneDYNC1I1chr7:77166962chr7:95705368ENST0000045705913172_123503.0629.0DCTN1
TgeneDYNC1I1chr7:77166962chr7:95705369ENST0000032497213172_123520.0646.0DCTN1
TgeneDYNC1I1chr7:77166962chr7:95705369ENST0000035938812162_123483.0609.0DCTN1
TgeneDYNC1I1chr7:77166962chr7:95705369ENST0000044746713172_123503.0629.0DCTN1
TgeneDYNC1I1chr7:77166962chr7:95705369ENST0000045705913172_123503.0629.0DCTN1
TgeneDYNC1I1chr7:77166961chr7:95705368ENST000003249721317147_163520.0646.0DYNLT1
TgeneDYNC1I1chr7:77166961chr7:95705368ENST000003593881216147_163483.0609.0DYNLT1
TgeneDYNC1I1chr7:77166961chr7:95705368ENST000004474671317147_163503.0629.0DYNLT1
TgeneDYNC1I1chr7:77166961chr7:95705368ENST000004570591317147_163503.0629.0DYNLT1
TgeneDYNC1I1chr7:77166962chr7:95705368ENST000003249721317147_163520.0646.0DYNLT1
TgeneDYNC1I1chr7:77166962chr7:95705368ENST000003593881216147_163483.0609.0DYNLT1
TgeneDYNC1I1chr7:77166962chr7:95705368ENST000004474671317147_163503.0629.0DYNLT1
TgeneDYNC1I1chr7:77166962chr7:95705368ENST000004570591317147_163503.0629.0DYNLT1
TgeneDYNC1I1chr7:77166962chr7:95705369ENST000003249721317147_163520.0646.0DYNLT1
TgeneDYNC1I1chr7:77166962chr7:95705369ENST000003593881216147_163483.0609.0DYNLT1
TgeneDYNC1I1chr7:77166962chr7:95705369ENST000004474671317147_163503.0629.0DYNLT1
TgeneDYNC1I1chr7:77166962chr7:95705369ENST000004570591317147_163503.0629.0DYNLT1


check button - Retained PPIs, but lost function due to frame-shift fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


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Related Drugs for PTPN12-DYNC1I1


check button Drugs targeting genes involved in this fusion gene.
(DrugBank Version 5.1.8 2021-05-08)
PartnerGeneUniProtAccDrugBank IDDrug nameDrug activityDrug typeDrug status

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Related Diseases for PTPN12-DYNC1I1


check button Diseases associated with fusion partners.
(DisGeNet 4.0)
PartnerGeneDisease IDDisease name# pubmedsSource